Guide to the Human Genome
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Search of human proteins with 239744621

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239744621 PREDICTED: hypothetical protein [Homo sapiens]
         (536 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239744621 PREDICTED: hypothetical protein [Homo sapiens]          1107   0.0  
gi|239755810 PREDICTED: hypothetical protein [Homo sapiens]          1033   0.0  
gi|239750310 PREDICTED: hypothetical protein [Homo sapiens]          1033   0.0  
gi|163965366 nascent polypeptide-associated complex alpha subuni...    63   8e-10
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    61   3e-09
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    61   3e-09
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    59   1e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    57   4e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    55   1e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   2e-07
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         55   2e-07
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]    54   3e-07
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]     54   3e-07
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]     54   3e-07
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]    54   3e-07
gi|112421108 capicua homolog [Homo sapiens]                            54   3e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    54   5e-07
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    52   1e-06
gi|33286446 opioid growth factor receptor [Homo sapiens]               51   2e-06
gi|113429443 PREDICTED: transmembrane protein 46-like [Homo sapi...    51   2e-06
gi|239755634 PREDICTED: hypothetical protein [Homo sapiens]            49   2e-05
gi|239749482 PREDICTED: hypothetical protein [Homo sapiens]            49   2e-05
gi|239744429 PREDICTED: hypothetical protein XP_002343157 [Homo ...    49   2e-05
gi|239743620 PREDICTED: hypothetical protein [Homo sapiens]            49   2e-05
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                49   2e-05
gi|153792074 proline rich 12 [Homo sapiens]                            49   2e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        48   2e-05
gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]            48   3e-05
gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo ...    48   3e-05
gi|55750053 atrophin-1 [Homo sapiens]                                  48   3e-05

>gi|239744621 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 536

 Score = 1107 bits (2863), Expect = 0.0
 Identities = 536/536 (100%), Positives = 536/536 (100%)

Query: 1   MLMKLLGEEQLPLVPGDKWTLKKKLDSLSPSHIVRDEMTSPDPDPASVNSSHLKAGLVPQ 60
           MLMKLLGEEQLPLVPGDKWTLKKKLDSLSPSHIVRDEMTSPDPDPASVNSSHLKAGLVPQ
Sbjct: 1   MLMKLLGEEQLPLVPGDKWTLKKKLDSLSPSHIVRDEMTSPDPDPASVNSSHLKAGLVPQ 60

Query: 61  SHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHLPAAALELCRAMLLPGTWFSLNRV 120
           SHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHLPAAALELCRAMLLPGTWFSLNRV
Sbjct: 61  SHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHLPAAALELCRAMLLPGTWFSLNRV 120

Query: 121 KESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGS 180
           KESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGS
Sbjct: 121 KESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGS 180

Query: 181 GTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGG 240
           GTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGG
Sbjct: 181 GTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGG 240

Query: 241 KQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPL 300
           KQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPL
Sbjct: 241 KQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPL 300

Query: 301 RSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSG 360
           RSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSG
Sbjct: 301 RSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSG 360

Query: 361 GGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGL 420
           GGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGL
Sbjct: 361 GGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGL 420

Query: 421 RDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRP 480
           RDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRP
Sbjct: 421 RDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRP 480

Query: 481 RAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLEATGTHAGSGTCQGSRG 536
           RAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLEATGTHAGSGTCQGSRG
Sbjct: 481 RAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLEATGTHAGSGTCQGSRG 536


>gi|239755810 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 499

 Score = 1033 bits (2672), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 38  MTSPDPDPASVNSSHLKAGLVPQSHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHL 97
           MTSPDPDPASVNSSHLKAGLVPQSHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHL
Sbjct: 1   MTSPDPDPASVNSSHLKAGLVPQSHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHL 60

Query: 98  PAAALELCRAMLLPGTWFSLNRVKESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYP 157
           PAAALELCRAMLLPGTWFSLNRVKESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYP
Sbjct: 61  PAAALELCRAMLLPGTWFSLNRVKESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYP 120

Query: 158 RPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNR 217
           RPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNR
Sbjct: 121 RPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNR 180

Query: 218 EAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLT 277
           EAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLT
Sbjct: 181 EAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLT 240

Query: 278 ALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAG 337
           ALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAG
Sbjct: 241 ALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAG 300

Query: 338 EGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPH 397
           EGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPH
Sbjct: 301 EGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPH 360

Query: 398 PQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRP 457
           PQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRP
Sbjct: 361 PQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRP 420

Query: 458 CPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSP 517
           CPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSP
Sbjct: 421 CPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSP 480

Query: 518 HLEATGTHAGSGTCQGSRG 536
           HLEATGTHAGSGTCQGSRG
Sbjct: 481 HLEATGTHAGSGTCQGSRG 499


>gi|239750310 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 499

 Score = 1033 bits (2672), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 38  MTSPDPDPASVNSSHLKAGLVPQSHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHL 97
           MTSPDPDPASVNSSHLKAGLVPQSHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHL
Sbjct: 1   MTSPDPDPASVNSSHLKAGLVPQSHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHL 60

Query: 98  PAAALELCRAMLLPGTWFSLNRVKESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYP 157
           PAAALELCRAMLLPGTWFSLNRVKESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYP
Sbjct: 61  PAAALELCRAMLLPGTWFSLNRVKESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYP 120

Query: 158 RPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNR 217
           RPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNR
Sbjct: 121 RPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNR 180

Query: 218 EAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLT 277
           EAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLT
Sbjct: 181 EAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLT 240

Query: 278 ALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAG 337
           ALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAG
Sbjct: 241 ALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAG 300

Query: 338 EGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPH 397
           EGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPH
Sbjct: 301 EGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPH 360

Query: 398 PQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRP 457
           PQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRP
Sbjct: 361 PQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRP 420

Query: 458 CPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSP 517
           CPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSP
Sbjct: 421 CPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSP 480

Query: 518 HLEATGTHAGSGTCQGSRG 536
           HLEATGTHAGSGTCQGSRG
Sbjct: 481 HLEATGTHAGSGTCQGSRG 499


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 130/549 (23%), Positives = 171/549 (31%), Gaps = 98/549 (17%)

Query: 43   PDPASVNSSHLKAGLVPQSHTPGRLVLAVLLQSLSPEGGLRAAEHRG---TGAWSPHLPA 99
            P P +      K G  P + +P    +       SP+GGL    H+G   T A +P  P 
Sbjct: 1080 PTPPAATPPSPKGG--PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137

Query: 100  AALELCRAMLLPGTWFSLNRVKESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYPRP 159
              L        P T         + T  S +G       G   PP        AA  P P
Sbjct: 1138 GGLATPPPKGAPTT--------PAATPPSPKG-------GLATPPPKGAPTTPAATPPSP 1182

Query: 160  TAGWRRHHSTGQPGAPVL------GGSGTAGNGGQRVSHR--------GICGPSPLQRLG 205
              G       G P  P        GG  T    G   +          G+  PSP    G
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK---G 1239

Query: 206  GSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSK 265
              T  A  P + +      P  G    P ++ P  K   A PP          +P     
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPK- 1298

Query: 266  LGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQAS 325
                G  A S     P P   T P     P  PP +  P   A + P        P+   
Sbjct: 1299 ----GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354

Query: 326  SSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRG-LRAGPRAPDAG 384
            SS GG  T  + EG           +    T    GG A    S  RG     P+     
Sbjct: 1355 SSKGGPTTPSSKEGP----------TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS 1404

Query: 385  SFWDPNPQTLAPHPQASRR-----------PRAGCSLSL-QPPHQRGLRDGCPSAAGRLS 432
                P     AP    +R            P A   +SL + P     + G  + + +  
Sbjct: 1405 PAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD 1464

Query: 433  PALPA---PSPREVTLGSHVPARVSRRPCPPTPAELN---------------PATSSPR- 473
            P LPA   PSP+E      V    S +  P TPA +                PAT S R 
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524

Query: 474  -PLGPLRPRAGGQSSG---------HPDRTVTSPRPIPARPRPR----TSASRPGPSPHL 519
             P+ P       ++            P  TV SP+  PA P P+    T +S+   SP  
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584

Query: 520  EATGTHAGS 528
                T+ G+
Sbjct: 1585 VTPSTYKGA 1593



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 99/406 (24%), Positives = 136/406 (33%), Gaps = 66/406 (16%)

Query: 143  PPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVL---GGSGTAGNGGQRVSHRGICGPS 199
            PP+  P   AA   P P          G P  P +      GT        S +G  GP+
Sbjct: 1305 PPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG--GPT 1361

Query: 200  PLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFS 259
                  G T  A  P ++       P    + GP    P G   T+P   P+   +   +
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSP--KRGPAIPSPKG-DPTSPAVIPLSPKKAPAT 1418

Query: 260  PLFSSKLGIHGDRAGSLTALRPNP-DLVTVPLTAHP---PVHPPLRSGPPLGAGSRPRAL 315
            P+  ++ G      G LT     P  L   P T+ P   P  P  +  P L A + P   
Sbjct: 1419 PV--TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPK 1476

Query: 316  CPAQTPSQASSSGGGRG-TSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGL 374
             P      A+SS   +   + A  G                TL +    +   +      
Sbjct: 1477 EPPAPKQVATSSSPKKAPATPAPMGAP--------------TLPAVIPSSPKEVPATPSS 1522

Query: 375  RAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPA 434
            R  P AP A       P TLAP              +L PP         PS   + +PA
Sbjct: 1523 RRDPIAPTATLLSKKTPATLAPKE------------ALIPPAMT-----VPSP--KKTPA 1563

Query: 435  LPAP-----SPREVTLGSHVPARVSRRPCPPTPAEL--NPATSSPRPLGPLRPRAGGQSS 487
            +P P     +P      S      S     P+P EL   PA +SP P     P       
Sbjct: 1564 IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP------- 1616

Query: 488  GHPDRTVTSPRPIPARPRPRTSASRPGPSP-HLEATGTHAGSGTCQ 532
              P  T  SP   PA P P+ + + P  +P  L+ + T   S TC+
Sbjct: 1617 --PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK 1660



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 75/310 (24%), Positives = 106/310 (34%), Gaps = 50/310 (16%)

Query: 240 GKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPD-----LVTVPLTAHP 294
           G    AP   PV+       PL  +        A     + P+P      L T+ L    
Sbjct: 679 GTVSLAPKNHPVKEGTLTTLPLVPT--------ASENCPVAPSPQNTCAPLATLVLAPEI 730

Query: 295 PVHPPLRSGPPLGAG---------SRPRALCP-AQTPSQASSSGGGRGTSGAGEGHQHLL 344
           P   P  S PP G           S   AL P A +P +  +   G   + + +G     
Sbjct: 731 PKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKG----- 785

Query: 345 ITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQAS--- 401
            T   L++    L       + R    +G  AGP  P        +P   +  P+ S   
Sbjct: 786 -TLTYLADSPSPLGVSVSPQTKRPPTKKG-SAGPDTPIGNLSSPVSPVEASFLPENSLSF 843

Query: 402 --RRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHV----PARVSR 455
              +     + S  PP  +G     PSA   LSP      P+E    S V    P     
Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPT--PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901

Query: 456 RPCPPTPAELNPATSSPR-------PLG-PLRPRAGGQSSGHPDRTVTSPRPIPARPRPR 507
            P P     L+  +SSP+       P G P  P   G  +  P  T  SP+  PA P P+
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP-PAATPPSPKGGPATPSPK 960

Query: 508 TSASRPGPSP 517
            + + P  +P
Sbjct: 961 WAPTPPAATP 970



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 41/156 (26%), Positives = 60/156 (38%), Gaps = 25/156 (16%)

Query: 380  APDAGSFWDPNPQ---TLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGR-LSPAL 435
            AP   +   P+P+      P P+ +  P A       PP  +G     P   G   +PA 
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAAT-----PPSPKGSPAATPLPKGAPTTPAA 1062

Query: 436  PAPSPR----------EVTLGSHVPARVSRRPCPPTP--AELNPATSSPRPLGPLR--PR 481
              PSP+            T  +  P      P  P+P  A + PA + P P G L   P 
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH 1122

Query: 482  AGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSP 517
             G  ++  P  T  SP+   A P P+ + + P  +P
Sbjct: 1123 KGAPTT--PAATPPSPKGGLATPPPKGAPTTPAATP 1156



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 12/136 (8%)

Query: 389  PNPQTL-APHPQ---ASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVT 444
            P P  +  P P+   A+  P+   +LS+     +  R   P+  G   PA P+P     T
Sbjct: 886  PTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR-ATPAPKG--IPASPSPKGAP-T 941

Query: 445  LGSHVPARVSRRPCPPTP--AELNPATSSPRPLG-PLRPRAGGQSSGHPDRTVTSPRPIP 501
              +  P      P  P+P  A   PA + P P G P  P   G  +  P  T  SP+  P
Sbjct: 942  PPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP-PAATPPSPKGGP 1000

Query: 502  ARPRPRTSASRPGPSP 517
            A P P+ + + P  +P
Sbjct: 1001 ATPSPKGAPTPPAVTP 1016


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 116/450 (25%), Positives = 157/450 (34%), Gaps = 72/450 (16%)

Query: 111 PGTWFSLNRVKESITAKSRRGKVLLEGT---GKEVPPRPLPAARAAARYPRPTAGWRRHH 167
           P T+   N  K ++    + G+  L      GK++  + +   R+A    +P        
Sbjct: 12  PPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLK-KTVTNDRSAPILDKPKGAGAGGG 70

Query: 168 STGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNREAHLRRKPRV 227
             G  G    GG G  G GG      G  GP  L    G   +A  P+ R    R     
Sbjct: 71  GGGFGGGGGFGGGGGGGGGGSF----GGGGPPGL----GGLFQAGMPKLRSTANRDNDSG 122

Query: 228 GLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPN----P 283
           G  P      PGG+  +A P  P      F  P    + G    +   +   RP+    P
Sbjct: 123 GSRPPLLP--PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180

Query: 284 DLVTVPLTAHP-PVH--PPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTS-GAGEG 339
           D +  P+ + P P+   P  R  PP+  G  PR   P  TP       G RGT+ G G  
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGG--PRQPSPGPTPPPFP---GNRGTALGGGSI 235

Query: 340 HQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGL--RAGPRAPDAGSFWDPNPQTLAPH 397
            Q  L +    SN             +  +  R L  +  P  P  G+    + + + P 
Sbjct: 236 RQSPLSSSSPFSNR----------PPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP 285

Query: 398 PQASRRP------RAGCSLSLQPPHQRGLRDGCP-----SAAGRLSPALPAPSPREVTLG 446
           P  + +P      R   S    PP     R G P     S+    +P LP    R ++L 
Sbjct: 286 PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQ---RNLSLS 342

Query: 447 SHVPARVS---RRPCPPTPAELNP--ATSSPRPLGPLRPRAGGQSSGHPDRT-------- 493
           S  P   S     P PP P+E  P      P   GPL P      +G   R         
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402

Query: 494 ----VTSPRPIPARPRP--RTSASRPGPSP 517
               V SPR  P  P P  R SA  P P P
Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 86/334 (25%), Positives = 104/334 (31%), Gaps = 91/334 (27%)

Query: 144 PRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQR 203
           PRP+ ++      P P  G  R  S G    P  G  GTA  GG           SPL  
Sbjct: 191 PRPIQSSPHNRGSP-PVPGGPRQPSPGPTPPPFPGNRGTALGGGS-------IRQSPLSS 242

Query: 204 LGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFS 263
               +   P P      L  KP     P P  + P   +E  PPP P    Q    P+ S
Sbjct: 243 SSPFSNRPPLPPTPSRALDDKPPP--PPPPVGNRPSIHREAVPPPPP----QNNKPPVPS 296

Query: 264 SKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQ 323
           +                P P   +    A PP  PP R GPP               P  
Sbjct: 297 T----------------PRPSASS---QAPPPPPPPSRPGPP---------------PLP 322

Query: 324 ASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDA 383
            SSSG         +    L      LS+    L S G             R+GP  P  
Sbjct: 323 PSSSGN--------DETPRLPQRNLSLSSSTPPLPSPG-------------RSGPLPP-- 359

Query: 384 GSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREV 443
                  P +  P P     P     L   PP  R   +G  S A   +P LP+ S    
Sbjct: 360 -------PPSERPPPPVRDPPGRSGPLPPPPPVSR---NGSTSRALPATPQLPSRS---- 405

Query: 444 TLGSHVPARVSRRPCPPTPAELNPATSSPRPLGP 477
             G   P    R P PP      P+  +P P  P
Sbjct: 406 --GVDSPRSGPRPPLPPD----RPSAGAPPPPPP 433



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 57/254 (22%), Positives = 76/254 (29%), Gaps = 31/254 (12%)

Query: 295 PVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTS----GAGEGHQHLLITYRVL 350
           PV PP    PP        AL   + P+   +   GR         G+  +  +   R  
Sbjct: 2   PVPPPPAPPPP-----PTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSA 56

Query: 351 SNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSL 410
             L +   +G G        G G   G      GSF    P  L    QA          
Sbjct: 57  PILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGM-------- 108

Query: 411 SLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATS 470
               P  R   +    + G   P LP             P+   R P P       P   
Sbjct: 109 ----PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEP 164

Query: 471 SPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPR----------PRTSASRPGPSPHLE 520
               + P RP  G +    P    ++PRPI + P           PR  +  P P P   
Sbjct: 165 QRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG 224

Query: 521 ATGTHAGSGTCQGS 534
             GT  G G+ + S
Sbjct: 225 NRGTALGGGSIRQS 238


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 116/450 (25%), Positives = 157/450 (34%), Gaps = 72/450 (16%)

Query: 111 PGTWFSLNRVKESITAKSRRGKVLLEGT---GKEVPPRPLPAARAAARYPRPTAGWRRHH 167
           P T+   N  K ++    + G+  L      GK++  + +   R+A    +P        
Sbjct: 12  PPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLK-KTVTNDRSAPILDKPKGAGAGGG 70

Query: 168 STGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNREAHLRRKPRV 227
             G  G    GG G  G GG      G  GP  L    G   +A  P+ R    R     
Sbjct: 71  GGGFGGGGGFGGGGGGGGGGSF----GGGGPPGL----GGLFQAGMPKLRSTANRDNDSG 122

Query: 228 GLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPN----P 283
           G  P      PGG+  +A P  P      F  P    + G    +   +   RP+    P
Sbjct: 123 GSRPPLLP--PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180

Query: 284 DLVTVPLTAHP-PVH--PPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTS-GAGEG 339
           D +  P+ + P P+   P  R  PP+  G  PR   P  TP       G RGT+ G G  
Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGG--PRQPSPGPTPPPFP---GNRGTALGGGSI 235

Query: 340 HQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGL--RAGPRAPDAGSFWDPNPQTLAPH 397
            Q  L +    SN             +  +  R L  +  P  P  G+    + + + P 
Sbjct: 236 RQSPLSSSSPFSNR----------PPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP 285

Query: 398 PQASRRP------RAGCSLSLQPPHQRGLRDGCP-----SAAGRLSPALPAPSPREVTLG 446
           P  + +P      R   S    PP     R G P     S+    +P LP    R ++L 
Sbjct: 286 PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQ---RNLSLS 342

Query: 447 SHVPARVS---RRPCPPTPAELNP--ATSSPRPLGPLRPRAGGQSSGHPDRT-------- 493
           S  P   S     P PP P+E  P      P   GPL P      +G   R         
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402

Query: 494 ----VTSPRPIPARPRP--RTSASRPGPSP 517
               V SPR  P  P P  R SA  P P P
Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 86/334 (25%), Positives = 104/334 (31%), Gaps = 91/334 (27%)

Query: 144 PRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQR 203
           PRP+ ++      P P  G  R  S G    P  G  GTA  GG           SPL  
Sbjct: 191 PRPIQSSPHNRGSP-PVPGGPRQPSPGPTPPPFPGNRGTALGGGS-------IRQSPLSS 242

Query: 204 LGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFS 263
               +   P P      L  KP     P P  + P   +E  PPP P    Q    P+ S
Sbjct: 243 SSPFSNRPPLPPTPSRALDDKPPP--PPPPVGNRPSIHREAVPPPPP----QNNKPPVPS 296

Query: 264 SKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQ 323
           +                P P   +    A PP  PP R GPP               P  
Sbjct: 297 T----------------PRPSASS---QAPPPPPPPSRPGPP---------------PLP 322

Query: 324 ASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDA 383
            SSSG         +    L      LS+    L S G             R+GP  P  
Sbjct: 323 PSSSGN--------DETPRLPQRNLSLSSSTPPLPSPG-------------RSGPLPP-- 359

Query: 384 GSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREV 443
                  P +  P P     P     L   PP  R   +G  S A   +P LP+ S    
Sbjct: 360 -------PPSERPPPPVRDPPGRSGPLPPPPPVSR---NGSTSRALPATPQLPSRS---- 405

Query: 444 TLGSHVPARVSRRPCPPTPAELNPATSSPRPLGP 477
             G   P    R P PP      P+  +P P  P
Sbjct: 406 --GVDSPRSGPRPPLPPD----RPSAGAPPPPPP 433



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 57/254 (22%), Positives = 76/254 (29%), Gaps = 31/254 (12%)

Query: 295 PVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTS----GAGEGHQHLLITYRVL 350
           PV PP    PP        AL   + P+   +   GR         G+  +  +   R  
Sbjct: 2   PVPPPPAPPPP-----PTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSA 56

Query: 351 SNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSL 410
             L +   +G G        G G   G      GSF    P  L    QA          
Sbjct: 57  PILDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGM-------- 108

Query: 411 SLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATS 470
               P  R   +    + G   P LP             P+   R P P       P   
Sbjct: 109 ----PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEP 164

Query: 471 SPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPR----------PRTSASRPGPSPHLE 520
               + P RP  G +    P    ++PRPI + P           PR  +  P P P   
Sbjct: 165 QRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPG 224

Query: 521 ATGTHAGSGTCQGS 534
             GT  G G+ + S
Sbjct: 225 NRGTALGGGSIRQS 238


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 131/508 (25%), Positives = 159/508 (31%), Gaps = 111/508 (21%)

Query: 40   SPDPDPASVNSSHLKAGLVPQSHTPGRLVLAVL-LQSLSPEGGLRA--AEHRGTGAWSPH 96
            +P P P   +  +      P  H+P      VL L   SP    R       G G+    
Sbjct: 1373 APQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKS 1432

Query: 97   LPAAALELCRAML--LPGTWFSLNRVKESITAKSRRGKVLLEGTGKEVPPRPLPAARAAA 154
            LPA+     R++L  LP T   +             G +LL+  G E PP P P      
Sbjct: 1433 LPASPPAARRSLLHRLPPTAPGV-------------GPLLLQ-LGTE-PPAPHPGVSKPW 1477

Query: 155  RYPRPTAGWR-----RHHSTGQPGAPVLGGSGTAGNGGQRV---SHRGICGPSPLQRLGG 206
            R   P    R     R     QP APV  G G     G  V   S R    PSP      
Sbjct: 1478 RSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRAS 1537

Query: 207  STGEAPR------------------------PRNREAHLRRKPRVGLEPGPHSSLPGGKQ 242
                 P                         P    ++   KP   L PGP   LP    
Sbjct: 1538 EENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPA 1597

Query: 243  ETAP-PPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHP-PVHPPL 300
               P PP P         P  ++        A SLT+       +T   +A P   HPP 
Sbjct: 1598 PATPLPPVP--------PPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPP- 1648

Query: 301  RSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSG 360
              GPP  A   P A  P   P   + SG     S +   H   L T    S L      G
Sbjct: 1649 --GPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHP--LETISSASTLSSLSAEG 1704

Query: 361  GGVASMRISVGRGLRAGPRAPDA----------GSFWDPN----PQTLAPHPQASRRPRA 406
            GG A      G G+ +GP   D           G    P     PQ + P     R    
Sbjct: 1705 GGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGR--AL 1762

Query: 407  GCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPC--PPT--- 461
            G S  L+P    GLRD          P  P  SP     G+     ++ R C  PPT   
Sbjct: 1763 GASGGLRPGPSGGLRD----------PVTPT-SPTVSVTGAGTDGLLALRACSGPPTAGV 1811

Query: 462  ------------PAELNPATSSPRPLGP 477
                        P  L  A+S PR L P
Sbjct: 1812 AGGPVAVEPEVPPVPLPTASSLPRKLLP 1839



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 89/391 (22%), Positives = 121/391 (30%), Gaps = 98/391 (25%)

Query: 140  KEVPPRPL--PAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICG 197
            +++PP P   P     +  P P+       S+G+      GG    G+GG          
Sbjct: 918  EDIPPPPTTSPPEPPYSTPPVPS-------SSGRLTPSPRGGPFNPGSGG---------- 960

Query: 198  PSPLQRLGGSTGEAPRPRNREAHLRRKP--RVGLEPGPHSSLPGGKQETAPPPQPVRTTQ 255
              PL     ++ + P P +     R K     G  P  H   P      APPPQP     
Sbjct: 961  --PLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQP----- 1013

Query: 256  TFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRAL 315
                         H   A                   HPP  P + +G        P  L
Sbjct: 1014 -------------HHHHA-------------------HPPHPPEMETGG--SPDDPPPRL 1039

Query: 316  CPAQTPSQASSSGGGRG-TSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGL 374
                 PS     GGG   T GA     H                +GGG  S +    R  
Sbjct: 1040 ALGPQPSLRGWRGGGPSPTPGAPSPSHHG--------------SAGGGGGSSQGPALRYF 1085

Query: 375  RAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLS---LQPPHQRGLRDGCPSAAGRL 431
            +  PRA  A  +           P  S R R G  +    ++   Q+G   G P A    
Sbjct: 1086 QLPPRAASAAMYV----------PARSGRGRKGPLVKQTKVEGEPQKG--GGLPPAPSPT 1133

Query: 432  SPALPAPSPREVTLGSH----VPARVSRRPCPPTPAELNPATSSP-RPLGPLRPRAGGQS 486
            SPA P P P            +P  + + P   +    +  +S+   P     P  GG  
Sbjct: 1134 SPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGG 1193

Query: 487  SGHPDRTVTSPRPIPARPRP-RTSASRPGPS 516
             G       +  P+P  P P  T AS  GP+
Sbjct: 1194 GGSSPSPAPAMSPVPPSPSPVPTPASPSGPA 1224



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 45/163 (27%), Positives = 55/163 (33%), Gaps = 23/163 (14%)

Query: 389  PNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPA----PSPREVT 444
            P P T  P P  S  P    S  L P  + G  +  P + G L  + PA    PSP +  
Sbjct: 922  PPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFN--PGSGGPLPASSPASFDGPSPPDTR 979

Query: 445  LGSHVPARVSRRPCPPT-----------PAELNPATSSPRPLGPLRPRAGGQSSGHPDRT 493
            +GS   +     P PP                 P      P  P     GG     P R 
Sbjct: 980  VGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRL 1039

Query: 494  VTSPRPIPARPR---PRTSASRPGPSPHLEATGTHAGSGTCQG 533
               P+P     R   P  +   P PS H  A G   G G+ QG
Sbjct: 1040 ALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGG---GGGSSQG 1079



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 91/389 (23%), Positives = 117/389 (30%), Gaps = 70/389 (17%)

Query: 179  GSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRN--------REAHLRRKPRVGLE 230
            GS   G GG   +      P PL  +   TG+A  P +        RE  L+     G  
Sbjct: 1316 GSRAYGGGGGSSAFTSFLPPRPL--VHPLTGKALDPASPLGLALAARERALKESSEGGGA 1373

Query: 231  PGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPL 290
            P P    P  + E  PP     +      P+         D A      R         L
Sbjct: 1374 PQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSL 1433

Query: 291  TAHPPV--HPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYR 348
             A PP      L   PP   G  P  L     P            S A E  + L +  R
Sbjct: 1434 PASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVR 1493

Query: 349  VLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRA-- 406
             L N +             ++ GRG    P + D      P+P+   P    S  PRA  
Sbjct: 1494 FLENCQ---------PRAPVTSGRG----PPSEDGPGVPPPSPRRSVPPSPTS--PRASE 1538

Query: 407  --GCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAE 464
              G  L + PP    +        G      P P P E +     P        P TP  
Sbjct: 1539 ENGLPLLVLPPPAPSV----DVEDGEFLFVEPLPPPLEFSNSFEKPES------PLTPGP 1588

Query: 465  LNPATSSPRPLGPLRPRAGGQSSGHP---DRTVTS-----------------------PR 498
             +P   +P P  PL P      +  P   D T +S                       P 
Sbjct: 1589 PHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPP 1648

Query: 499  PIPARPRPRTSASRPGPSPHLEATGTHAG 527
              PA   P  +A +PGP P     GT +G
Sbjct: 1649 GPPAPAAPAPAAPQPGPDP---PPGTDSG 1674



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 49/162 (30%), Positives = 60/162 (37%), Gaps = 15/162 (9%)

Query: 378  PRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLS--PAL 435
            P     GS  DP P+ LA  PQ S R   G   S  P        G     G  S  PAL
Sbjct: 1024 PEMETGGSPDDPPPR-LALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPAL 1082

Query: 436  P--APSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRT 493
                  PR  +   +VPAR  R           P     +  G   P+ GG     P  T
Sbjct: 1083 RYFQLPPRAASAAMYVPARSGR-------GRKGPLVKQTKVEG--EPQKGGGLPPAPSPT 1133

Query: 494  V-TSPRPIPARPRPRTSASRPGPSPHLEATGTHAGSGTCQGS 534
               SP+P PA   P    S P P+  ++A  T +   + QGS
Sbjct: 1134 SPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGS 1175



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 100/432 (23%), Positives = 136/432 (31%), Gaps = 87/432 (20%)

Query: 142  VPPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGI------ 195
            VPP P P    A+     T  +     T Q GA ++G +   G        R        
Sbjct: 1207 VPPSPSPVPTPASPSGPATLDF-----TSQFGAALVGAARREGGWQNEARRRSTLFLSTD 1261

Query: 196  CGPSPLQRLGGSTGEAPRPRNR------EAHLRRKPRVGLEP----------GPHSSLPG 239
             G       G  TG AP PR R      E     +P + LE           G  S   G
Sbjct: 1262 AGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYG 1321

Query: 240  GKQETAP-----PPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHP 294
            G   ++      PP+P+    T  +   +S LG+    A    AL+ + +    P     
Sbjct: 1322 GGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLA--LAARERALKESSEGGGAPQPPPR 1379

Query: 295  PVHPPLRSGPPLGAGSRPRA-------LCPAQTPSQASSSGGGRGTSGAGEGHQHLLITY 347
            P  P   + PP      P A       L  A  P  A    G R   G+ E         
Sbjct: 1380 PPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPA 1439

Query: 348  RVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAG------SFWDPNPQTLAPHPQ-- 399
               S L R   +  GV  + + +G      P AP  G      S     P+ L  H +  
Sbjct: 1440 ARRSLLHRLPPTAPGVGPLLLQLG----TEPPAPHPGVSKPWRSAAPEEPERLPLHVRFL 1495

Query: 400  ASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCP 459
             + +PRA  +    PP + G             P +P PSPR              R  P
Sbjct: 1496 ENCQPRAPVTSGRGPPSEDG-------------PGVPPPSPR--------------RSVP 1528

Query: 460  PTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIP-------ARPRPRTSASR 512
            P+P     +  +  PL  L P A        +     P P P        +P    +   
Sbjct: 1529 PSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGP 1588

Query: 513  PGPSPHLEATGT 524
            P P P   A  T
Sbjct: 1589 PHPLPDTPAPAT 1600



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 37/119 (31%), Positives = 49/119 (41%), Gaps = 13/119 (10%)

Query: 137  GTGKEVPPRPLPAARAAARYPRPTA-GWRRHHSTGQPGAPVLGGSGTAGNGG---QRVSH 192
            G+  + PPR        A  P+P+  GWR    +  PGAP     G+AG GG   Q  + 
Sbjct: 1030 GSPDDPPPR-------LALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPAL 1082

Query: 193  RGICGPSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAP-PPQP 250
            R    P P          A   R R+  L ++ +V  EP     LP     T+P  PQP
Sbjct: 1083 RYFQLP-PRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQP 1140



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 88/356 (24%), Positives = 112/356 (31%), Gaps = 84/356 (23%)

Query: 59   PQSHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHLPAAALELCRAMLLPGTWFSLN 118
            PQ  TP +L      ++L   GGLR     G     P  P +           G   +L 
Sbjct: 1749 PQLMTPSKL----RGRALGASGGLRPGPSGGLR--DPVTPTSPTVSVTGAGTDGL-LALR 1801

Query: 119  RVKESITAKSRRGKVLLEGTGKEVPPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLG 178
                  TA    G V +E    EVPP PLP    A+  PR    W      G P  P+ G
Sbjct: 1802 ACSGPPTAGVAGGPVAVE---PEVPPVPLP---TASSLPRKLLPW--EEGPGPPPPPLPG 1853

Query: 179  GSGTAGNGGQRVSHRGICG--PSPLQRLGGST---------------------GEAPRPR 215
                            I     S LQ+ GGS+                     G A    
Sbjct: 1854 PLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVP 1913

Query: 216  NREAHLRRK-----PRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHG 270
             R + L+R+      +  L   P SSL    Q    PP P   T T  SP  ++  G   
Sbjct: 1914 ERTSSLQRQRLSDDSQSSLLSKPVSSL---FQNWPKPPLPPLPTGTGVSPTAAAAPGATS 1970

Query: 271  DRAGS------------------LTALRPNPDLV--------------TVPLTAHPPVHP 298
              A S                  L    P+P L+              ++P+    P++P
Sbjct: 1971 PSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYP 2030

Query: 299  PL---RSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLS 351
             L   R  P  GAG       P   P     SG   G  GA  G    L   R+LS
Sbjct: 2031 GLFDIRGSPTGGAGGSADPFAPVFVPPHPGISG---GLGGALSGASRSLSPTRLLS 2083



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 135/574 (23%), Positives = 181/574 (31%), Gaps = 151/574 (26%)

Query: 77   SPEGGLRAAEHRGT---GAWSPHLPAAALELCRAMLLPGTWFSLNRVKESITAKSRRGKV 133
            SP  G  +  H G+   G  S   PA      R   LP    S      + + + R+G +
Sbjct: 1056 SPTPGAPSPSHHGSAGGGGGSSQGPAL-----RYFQLPPRAASAAMYVPARSGRGRKGPL 1110

Query: 134  L----LEGT---GKEVPPRPLPAARAAARYPRPTAGWRRHH------------STGQPGA 174
            +    +EG    G  +PP P P + A+ + P   A     +            ST   G 
Sbjct: 1111 VKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGR 1170

Query: 175  PVLGGS------------GTAGNGGQRVSHRGICG---------PSPLQRLGGST----- 208
               G S            G  G GG   S               P+P    G +T     
Sbjct: 1171 SSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTS 1230

Query: 209  -------GEAPRPRNREAHLRRKPRVGL--EPGPHSSLPGGKQETAPPPQPVRTTQTFFS 259
                   G A R    +   RR+  + L  + G      GG    A P   +R +++   
Sbjct: 1231 QFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDE 1290

Query: 260  PLFSSKLGIHGDRAGSLTAL------------RPNPDLVTVPLTAHPPVHP----PLRSG 303
             +FS++  +  + AGS                       T  L   P VHP     L   
Sbjct: 1291 GMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPA 1350

Query: 304  PPLGAGSRPRALCPAQTPSQASSSGGG------RGTSGAGEG----------HQHLLITY 347
             PLG      AL   +   + SS GGG      R  S   E           H H     
Sbjct: 1351 SPLGL-----ALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVL 1405

Query: 348  RVL-----SNLRRTLCSGGGVASMRISV-------GRGL--RAGPRAPDAGS-FWDPNPQ 392
            R+         RR L    G+ S   S+        R L  R  P AP  G        +
Sbjct: 1406 RLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTE 1465

Query: 393  TLAPHPQASRRPRAGCSLSLQ--PPHQRGLRDGCPSA---AGR-----LSPALPAPSPRE 442
              APHP  S+  R+      +  P H R L +  P A   +GR       P +P PSPR 
Sbjct: 1466 PPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRR 1525

Query: 443  VTLGSHVPARVSRR----------PCP-------------PTPAELNPATSSPRPLGPLR 479
                S    R S            P P             P P  L  + S  +P  PL 
Sbjct: 1526 SVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLT 1585

Query: 480  PRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRP 513
            P   G     PD T     P+P  P P  +A+ P
Sbjct: 1586 P---GPPHPLPD-TPAPATPLPPVPPPAVAAAPP 1615



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 46/158 (29%), Positives = 56/158 (35%), Gaps = 27/158 (17%)

Query: 388 DPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCP--------SAAGRLSPALPAPS 439
           D  P   +P   A RR   G  L++ P   R   D           SA G  S   P P 
Sbjct: 406 DVVPFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGP- 464

Query: 440 PREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSG-HPDRTVTSPR 498
               T GS   ++ S    P T        S+  P G    RA   S G HP+     PR
Sbjct: 465 ----TSGSQGQSQPS---APTTKLSSGTLRSASSPRGA---RARSPSRGRHPEDAKRQPR 514

Query: 499 PIPARPRPRTSASRPGPSPHLEATGTHAGSGTCQGSRG 536
             P+     +   R GP+     TG   G G   GSRG
Sbjct: 515 GRPSS----SGTPREGPAG---GTGGSGGPGGSLGSRG 545


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 110/427 (25%), Positives = 148/427 (34%), Gaps = 74/427 (17%)

Query: 126 AKSRRGKVLLEGTGKEVP-PRPLPAARAA--ARYPRPTAGWRRHHSTGQPGAPVLGGSGT 182
           A +RR +      G EV  PRP P+AR       PR +      HST +P +P      +
Sbjct: 175 AMARRSRA----AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP-SPAARRRPS 229

Query: 183 AGNGGQRVSHRGICGPS-PLQ---RLGGSTGEAPRPRNREAHLRRKPRVGLEP------- 231
           AG G QR + R +   + PL    R G S    PR     +  + K    L P       
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289

Query: 232 -------GPHSSLP-------GGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLT 277
                  GP SS P       G K    PPP    T      P  S  L      A    
Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP-SPPLATPLPLAPPSP 348

Query: 278 ALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAG 337
           +  P+   +  P    P   PP  + PP+ A    + + P Q P   +S       S   
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL- 407

Query: 338 EGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPH 397
                       LS+L+ T   G        S    L   PR   A      +P   A  
Sbjct: 408 -----------ALSSLQATTSLGSPTLQATHSF---LTMSPRQTQASL---TSPSRPAST 450

Query: 398 PQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPAL-PAPSPREVTLGSHVPARVSRR 456
           P  S   +A  SL   PP Q             LSPA+ P  SP  +     + +  S  
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTS-----------LSPAVSPLSSPLTIHPLQALSSLASHS 499

Query: 457 PCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSP--RPIPA-RPRPRTSASRP 513
           P  P  + + P   +   L P        S   P  ++T+P    +P+  P P  +AS P
Sbjct: 500 PQAPLSSLIMPPLETQSSLAP-------PSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552

Query: 514 GPSPHLE 520
             +PHLE
Sbjct: 553 LTTPHLE 559



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 89/340 (26%), Positives = 104/340 (30%), Gaps = 65/340 (19%)

Query: 198  PSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTF 257
            PSP      S    P PR     L   P + + P P +SLP       PP  P       
Sbjct: 739  PSPPASPPMSPSATPPPR--VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796

Query: 258  FSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCP 317
               L S      G    S     P+  L   PL   PP  PP+ + P L     P A   
Sbjct: 797  LQALPSPPASFPGQAPFS-----PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851

Query: 318  AQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAG 377
             Q P +  + G     SG                  R TL                L  G
Sbjct: 852  LQAPRRPPTPGPDTSVSGP-----------------RLTL---------------ALAPG 879

Query: 378  PRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSL--QPPHQRGLRDGCPSAAGRLSPAL 435
            P          P P + +P    S    AG S S    P   RG   G P      SP  
Sbjct: 880  P----------PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG-PEGGAAASP-- 926

Query: 436  PAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVT 495
                P +  L +  PA  SR P PP      P    P P     P  G  S+        
Sbjct: 927  ----PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP-----PATGPGSADGLCTIYE 977

Query: 496  SPRPIPARPRPRTSASRPGPSPHLEATGTHAGSGTCQGSR 535
            +  P  A P P   A  PGPSP        AG+G    SR
Sbjct: 978  TEGPESATPAP--GALDPGPSPGTSGGKAAAGAGAGASSR 1015



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 106/398 (26%), Positives = 127/398 (31%), Gaps = 61/398 (15%)

Query: 148 PAARAAARY-PRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICG---PSPLQR 203
           PAARA     PRP    R           VLG +G  G         GI G   P    R
Sbjct: 17  PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76

Query: 204 LG-------GSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPP-------- 248
            G        S   A RP       R  P     PGP SS       T P P        
Sbjct: 77  AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136

Query: 249 ---QPVRTTQTFFSPLFSS-KLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGP 304
              + V   +   +P  S+   G   D +G  T   P+P +      A   V  P    P
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGP-TPGTPSPAMARRSRAAGTEVGLPR---P 192

Query: 305 PLGAGSRPRALCPAQTPSQASS------SGGGRGTSGAGEGHQHLLITYRVLSNLRRTLC 358
              A  RP    P ++ S AS       S   R    AG G Q             R+L 
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR---------PASRSLS 243

Query: 359 SGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQR 418
           S     S     G   R  PRAP   S   P P+ L    QA R P+      + PP   
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPS--QPKPKGL----QALRPPQ------VTPPR-- 289

Query: 419 GLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPL 478
             +D  P+     S  L  PSP         P   +  P P T    +P  ++P PL P 
Sbjct: 290 --KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP-SPPLATPLPLAPP 346

Query: 479 RPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPS 516
            P A       P    T P   P  P   T   +  PS
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAP--PSMTTPPMQAPPS 382



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 81/326 (24%), Positives = 101/326 (30%), Gaps = 54/326 (16%)

Query: 214 PRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPL---FSSKLGIHG 270
           PR  +A L    R    P     L       A PP      QT  SP     SS L IH 
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP-----LQTSLSPAVSPLSSPLTIHP 488

Query: 271 DRAGSLTALR----PNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASS 326
            +A S  A      P   L+  PL     + PP    PP    + P    P+  P    +
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548

Query: 327 SGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSF 386
           +     T                  +L    C     A   +         P      S 
Sbjct: 549 ASAPLTTP-----------------HLETPPCP----APCPLQAPPSPLTTPPPETPSSI 587

Query: 387 WDPNPQT----LAP----------HPQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLS 432
             P PQ      +P           P A+  P+A   L+L PP Q       P A+  LS
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL-PPLQA---PPSPPASPPLS 643

Query: 433 P-ALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPD 491
           P A P+P          + A  S  P PP  A  +P  S P       P     S   P 
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 703

Query: 492 RTVTSPRPIPARPRPRTSASRPGPSP 517
             V  P   PA P    SA+ P  +P
Sbjct: 704 LQV--PPSPPASPPMSPSATPPPQAP 727


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 94/364 (25%), Positives = 115/364 (31%), Gaps = 85/364 (23%)

Query: 166 HHSTGQPGAPVL--GGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNREAHLRR 223
           HH    P  P +    +G  GN     S  G  G  P     G+ G AP P         
Sbjct: 39  HHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEP--------- 89

Query: 224 KPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNP 283
            P     PG      GG  +   PP P R       PL      +    A     LRP P
Sbjct: 90  PPAGRARPG------GGGPQRPGPPSPRR-------PL------VPAGPAPPAAKLRPPP 130

Query: 284 D-----LVTVPLTAHPPVHP-PLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAG 337
           +        VP  A     P P  +GP   AG  P AL     P      G G G  G G
Sbjct: 131 EGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAG--PAALAARAGPGPGPGPGPGPGP-GPG 187

Query: 338 EGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPH 397
           +                    +G G A         L +   A  A S  +  P  L P 
Sbjct: 188 KP-------------------AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPL 228

Query: 398 PQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRP 457
           P    +P A  ++   PP         P+A     PA PA            PA  +  P
Sbjct: 229 P----KPAAPGTVIQTPPFVGAAAPPAPAAPS--PPAAPA------------PAAPAAAP 270

Query: 458 CPPTPAELNPATSSPRPLGP------LRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSAS 511
            PP PA    A     P GP      + P A  Q+ G       +P P PA   P   + 
Sbjct: 271 PPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAG---AAPAPAPAAGGPAGVSG 327

Query: 512 RPGP 515
           +PGP
Sbjct: 328 QPGP 331



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 109/465 (23%), Positives = 141/465 (30%), Gaps = 94/465 (20%)

Query: 68  VLAVLLQSLSPEGGLRAAEHRGTGAWSPHLPAAALELCRAMLLPGTWFSLNRVKESITAK 127
           V++ L+ SL  +    AA H      +P + AAA       ++ G+         +  A+
Sbjct: 21  VVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAE 80

Query: 128 SR---------RGKVLLEGTGKEVPPRPLPAARAAARYPRPTAGWRRHHSTGQPG--APV 176
                       G+    G G + P  P P        P P A   R    G  G  APV
Sbjct: 81  GAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV 140

Query: 177 LGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGP--- 233
              +  A   G   +  G   P+    L    G  P P          P  G  PGP   
Sbjct: 141 PAAAAVAA--GPEPAPAGPAKPAGPAALAARAGPGPGP---------GPGPGPGPGPGKP 189

Query: 234 -------------------HSSLP------GGKQETAPPPQPVRTTQTFFSPLFSSKLGI 268
                              H++ P       G     P P+P        +P F      
Sbjct: 190 AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249

Query: 269 HGDRAGSLTALRPNPDLVTVPLTAHPPVHP-PLRSGPPLGAGSRPRALCPAQTPSQASSS 327
               A S  A  P P     P  A PP  P P     P G  + P    PA  P  A+ +
Sbjct: 250 PAPAAPSPPA-APAP---AAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQN 305

Query: 328 GGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGS-- 385
           GG  G + A                      + GG A +    G G  A   AP   +  
Sbjct: 306 GGSAGAAPA-------------------PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAES 346

Query: 386 ------FWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPS 439
                    P  QTLA    AS       S+ + P  Q  L    PS A    PA   P+
Sbjct: 347 PKRVVQAAPPAAQTLAASGPAS----TAASMVIGPTMQGAL----PSPAAVPPPAPGTPT 398

Query: 440 PREVTLGSHVPARVSRRPCPPTP---AELNPATSSPR-PLGPLRP 480
                    V   +SR P   T    A L P   +PR P  P  P
Sbjct: 399 GLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 56/227 (24%), Positives = 71/227 (31%), Gaps = 26/227 (11%)

Query: 302 SGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLR-RTLCSG 360
           +GP   A   P A        +A   GGG    G     + L+         + R    G
Sbjct: 73  AGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEG 132

Query: 361 GGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGL 420
              +   +     + AGP    AG      P  LA         RAG      P    G 
Sbjct: 133 SAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAA--------RAGPGPGPGPGPGPGP 184

Query: 421 RDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGP--- 477
             G P+  G    A    +     L SH  A  +       PA L P    P+P  P   
Sbjct: 185 GPGKPAGPG----AAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPL---PKPAAPGTV 237

Query: 478 --LRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLEAT 522
               P  G  +   P     +P P PA P P   A+ P P P   AT
Sbjct: 238 IQTPPFVGAAAPPAP----AAPSP-PAAPAPAAPAAAPPPPPPAPAT 279


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 112/404 (27%), Positives = 135/404 (33%), Gaps = 72/404 (17%)

Query: 148 PAARAAARY-PRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICG---PSPLQR 203
           PAARA     PRP    R           VLG +G  G         GI G   P    R
Sbjct: 17  PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76

Query: 204 LG-------GSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPP-------- 248
            G        S   A RP       R  P     PGP SS       T P P        
Sbjct: 77  AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136

Query: 249 ---QPVRTTQTFFSPLFSS-KLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGP 304
              + V   +   +P  S+   G   D +G  T   P+P +      A   V  P    P
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGP-TPGTPSPAMARRSRAAGTEVGLPR---P 192

Query: 305 PLGAGSRPRALCPAQTPSQASS------SGGGRGTSGAGEGHQHLLITYRVLSNLRRTLC 358
              A  RP    P ++ S AS       S   R    AG G Q             R+L 
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR---------PASRSLS 243

Query: 359 SGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQR 418
           S     S     G   R  PRAP   S   P P+ L    QA R P+      + PP   
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPS--QPKPKGL----QALRPPQ------VTPPR-- 289

Query: 419 GLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPL 478
             +D  P+     S  L  PSP    L S  P  +   P  P  + L    ++P PL P 
Sbjct: 290 --KDAAPALGPLSSSPLATPSP-SAALQSQAPPTL---PATPHSSSLTCQLATPLPLAPP 343

Query: 479 RPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLEAT 522
            P A       P    T P P PA P  + + S    SP L+AT
Sbjct: 344 SPSA-------PPSLQTLPSP-PATPPSQATTSL--GSPTLQAT 377



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 103/404 (25%), Positives = 130/404 (32%), Gaps = 88/404 (21%)

Query: 126 AKSRRGKVLLEGTGKEVP-PRPLPAARAA--ARYPRPTAGWRRHHSTGQPGAPVLGGSGT 182
           A +RR +      G EV  PRP P+AR       PR +      HST +P +P      +
Sbjct: 175 AMARRSRA----AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP-SPAARRRPS 229

Query: 183 AGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQ 242
           AG G QR + R          L  S      P       R  PR    P      P G Q
Sbjct: 230 AGGGLQRPASRS---------LSSSATPLSSPARSGPSARGTPRAPAHPSQPK--PKGLQ 278

Query: 243 ETAPPP--QPVRTTQTFFSPLFSSKLGIHG------DRAGSLTALRPNPDLVTVPLTAHP 294
              PP    P +       PL SS L           +A       P+   +T  L    
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338

Query: 295 PVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLR 354
           P+ PP  S PP     +     PA  PSQA++S G                         
Sbjct: 339 PLAPPSPSAPP---SLQTLPSPPATPPSQATTSLGS------------------------ 371

Query: 355 RTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQP 414
                                  P      SF    P +    P A+  P+A  +L+L P
Sbjct: 372 -----------------------PTLQATHSFLPSPPLS----PLATPPPQAPPALAL-P 403

Query: 415 PHQRGLRDGCPSAAGRLSP-ALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPR 473
           P Q       P A+  LSP A P+P          + A  S  P PP  A  +P  S P 
Sbjct: 404 PLQA---PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460

Query: 474 PLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSP 517
                 P     S   P   V  P   PA P    SA+ P  +P
Sbjct: 461 SPSATPPSQAPPSLAAPPLQV--PPSPPASPPMSPSATPPPQAP 502



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 68/257 (26%), Positives = 80/257 (31%), Gaps = 58/257 (22%)

Query: 281 PNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGH 340
           P+  L   PL   PP  PP+ + P L     P A    Q P +  + G     SG     
Sbjct: 546 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP---- 601

Query: 341 QHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQA 400
                        R TL                L  GP          P P + +P    
Sbjct: 602 -------------RLTL---------------ALAPGP----------PPPPSRSPSSTL 623

Query: 401 SRRPRAGCSLSL--QPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPC 458
           S    AG S S    P   RG   G P      SP      P +  L +  PA  SR P 
Sbjct: 624 SGPDLAGHSSSATSTPEELRGYDSG-PEGGAAASP------PPDAELAACHPAAWSRGPA 676

Query: 459 PPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPH 518
           PP      P    P P     P  G  S+        +  P  A P P   A  PGPSP 
Sbjct: 677 PPLAFRGAPGAPLPWP-----PATGPGSADGLCTIYETEGPESATPAP--GALDPGPSPG 729

Query: 519 LEATGTHAGSGTCQGSR 535
                  AG+G    SR
Sbjct: 730 TSGGKAAAGAGAGASSR 746



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 51/192 (26%), Positives = 68/192 (35%), Gaps = 25/192 (13%)

Query: 354 RRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQ 413
           +R     G  A    +   GL   PR P  GS   P P T    P A R   A  ++  +
Sbjct: 4   KRDKAKAGAAARTPAARAPGLLT-PRPP--GSPRPPPPVT----PAALRVLGAAGAVGRK 56

Query: 414 PPHQRGLRDG---CPSAAGRLSPAL--------PAPSPREVTLGSHVPARVSRRPCPPTP 462
           P  +R    G    P +A R  P          PA  P     G   P   +  P P + 
Sbjct: 57  PLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116

Query: 463 AELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPR--PIPARPRPRTSASRPG-PSPHL 519
                 T+ P PLG    R   + +    +   +P+   + A  R  TS   PG PSP +
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 520 ----EATGTHAG 527
                A GT  G
Sbjct: 177 ARRSRAAGTEVG 188


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 111/420 (26%), Positives = 140/420 (33%), Gaps = 81/420 (19%)

Query: 179 GSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAP-RPRNREAHLRRKPRVGLEPG---PH 234
           G+   G   +R +   +  P P   L G +GE    P  +        + GL PG   P 
Sbjct: 189 GAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPP 248

Query: 235 SSLPGGKQETAPPPQPVRTTQTFFSPLFS-SKLGI----HGD-----RAGSLTALR---- 280
             LP       PPP P+    T  SP F  +K G+    HGD     R GS    R    
Sbjct: 249 PPLPPPPPPPPPPPPPLPGLAT--SPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQR 306

Query: 281 ---PNPDLVTVPL-TAHPPVHPPLRSGPPLGAGSRP-----RALCPAQTPS----QASSS 327
              P+P     P  TAHPP H  + + PP G G RP         PA  P     + S  
Sbjct: 307 HSLPHPYPYPAPAYTAHPPGHRLVPAAPP-GPGPRPPGAESHGCLPATRPPGSDLRESRV 365

Query: 328 GGGRGTSGAGEGHQHLLITYRVL--SNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGS 385
              R  S          + Y       L  T  S    +S    + RG+   P  P A  
Sbjct: 366 QRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGL-RGVEPNPGIPGADH 424

Query: 386 FWDPNPQT-----LAPHPQASRRPRAGC-----SLSL--------QPPHQRGLRDGCPSA 427
           +  P  +      L P   +SR+P  G       LSL         PP  R LR   P  
Sbjct: 425 YQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP-PPP 483

Query: 428 AGRLSPALPAPSP-----REVTLGSHVPARVSRRPCPPTPAELNPATS-----------S 471
           A    PA  A         E+  G+  P R +  P P     L P  S            
Sbjct: 484 AWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTP 543

Query: 472 PRPLGPLRPRAGGQSSGH---PDRTVTSPRP------IPARPRPRTSASRPGPSPHLEAT 522
           P P  P    +   S  H   P   V+ P P      I   PRP + A  P   P +  T
Sbjct: 544 PTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLT 603



 Score = 36.6 bits (83), Expect = 0.059
 Identities = 33/102 (32%), Positives = 40/102 (39%), Gaps = 26/102 (25%)

Query: 411 SLQPPHQRGLRD----GCPSAAGRLSPALPAPSPREVTL-GSHVPARVSRRPCPPTPAEL 465
           ++ PP  R  R+    G  S AG  S   P P PR   L G    A + +   PP PA L
Sbjct: 4   AVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQ---PPLPAPL 60

Query: 466 NPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPR 507
            P+               G SSGHP +    P   P  P PR
Sbjct: 61  PPSH--------------GSSSGHPSK----PYYAPGAPTPR 84



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 64/256 (25%), Positives = 80/256 (31%), Gaps = 89/256 (34%)

Query: 16  GDKWTLKKKLDSLSPSHIVRDEMTSPDPDPASVNSSHLKAGLVPQSHTPGRLVLAVLLQS 75
           GD W  ++K  +       R  +  P P PA   ++H      P  H   RLV A     
Sbjct: 287 GDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAH------PPGH---RLVPA----- 332

Query: 76  LSPEGGLRAAEHRGTGAWSPHLPAAALELCRAMLLPGTWFSLNRVKESITAKSRRGKVLL 135
            +P G              P  P A    C    LP T    + ++ES   +SR    + 
Sbjct: 333 -APPGP------------GPRPPGAESHGC----LPATRPPGSDLRESRVQRSRMDSSVS 375

Query: 136 EGTGKEVPPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQR------ 189
                       PAA  A     P+         G PG      S ++ N G R      
Sbjct: 376 ------------PAATTACVPYAPS------RPPGLPGTTTSSSSSSSSNTGLRGVEPNP 417

Query: 190 --------------VSHRGICGPSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPG-PH 234
                         VSH G  GPS                   AH  RKP +G     PH
Sbjct: 418 GIPGADHYQTPALEVSHHGRLGPS-------------------AHSSRKPFLGAPAATPH 458

Query: 235 SSLPGGKQETAPPPQP 250
            SLP G     PPP P
Sbjct: 459 LSLPPGPSSPPPPPCP 474



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 79/360 (21%), Positives = 113/360 (31%), Gaps = 88/360 (24%)

Query: 143  PPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQ 202
            PP  LP     A++P P+    +      P    L  S  +   GQ+  +RG        
Sbjct: 771  PPPALPPPPPLAKFPPPSQP--QPPPPPPPSPASLLKSLASVLEGQKYCYRGT------- 821

Query: 203  RLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPP-----PQPVRTTQTF 257
              G +    P P          P     PGP S        +A P     PQP  ++ + 
Sbjct: 822  --GAAVSTRPGPL---------PTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQ 870

Query: 258  FS----PLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPV----------------- 296
            FS    P    +        G +T  +P P L   P  +   V                 
Sbjct: 871  FSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGR 930

Query: 297  -----HPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLS 351
                   P+ +  P  +G+  R L PAQ   +A   GG    SG+ +  Q     ++   
Sbjct: 931  SATDPADPVDTAEPADSGTE-RLLPPAQAKEEA---GGVAAVSGSCKRRQK---EHQKEH 983

Query: 352  NLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLS 411
               R  C          SVGR  R G              +  A  P+   R   G +L 
Sbjct: 984  RRHRRACKD--------SVGRRPREG------------RAKAKAKVPKEKSRRVLG-NLD 1022

Query: 412  LQPPHQRGLRDGCPSAAGRLS---------PALPAPSPREVTLGSHVPARVSRRPCPPTP 462
            LQ    +G     P   G            P+ PAPS +     + VP + +R   P  P
Sbjct: 1023 LQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPP 1082


>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 59/213 (27%), Positives = 75/213 (35%), Gaps = 28/213 (13%)

Query: 139 GKEVPPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGP 198
           G++VP  P    R     P P    R  H  G P +  L G+G   N        G+ G 
Sbjct: 483 GQQVPGFPTAPTRVVIARPTPPQA-RPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQ 541

Query: 199 ---SPLQRLGGSTGEAPRPRNREAHLRR-KPRVGLEPGPHSSLPGGKQETAPPPQPVRTT 254
               P+    G+ G AP P    A             GP    PGG  +  P PQP    
Sbjct: 542 LLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGP---APGGPAQPPPTPQP-SMA 597

Query: 255 QTFFSPLFSSKLGIHGDRAG-------SLTALRPN--------PDLVTVPLTAHPPVHPP 299
              FS L  + LG  G  AG       ++T   P          D +    TA PP  PP
Sbjct: 598 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPP 657

Query: 300 LRSGPPLGAGSRPRALCPAQTPSQASSSGGGRG 332
               PP       + + P  +PS  + S GG G
Sbjct: 658 ----PPPPPAPEQQTMPPPGSPSGGAGSPGGLG 686


>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 59/213 (27%), Positives = 75/213 (35%), Gaps = 28/213 (13%)

Query: 139 GKEVPPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGP 198
           G++VP  P    R     P P    R  H  G P +  L G+G   N        G+ G 
Sbjct: 483 GQQVPGFPTAPTRVVIARPTPPQA-RPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQ 541

Query: 199 ---SPLQRLGGSTGEAPRPRNREAHLRR-KPRVGLEPGPHSSLPGGKQETAPPPQPVRTT 254
               P+    G+ G AP P    A             GP    PGG  +  P PQP    
Sbjct: 542 LLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGP---APGGPAQPPPTPQP-SMA 597

Query: 255 QTFFSPLFSSKLGIHGDRAG-------SLTALRPN--------PDLVTVPLTAHPPVHPP 299
              FS L  + LG  G  AG       ++T   P          D +    TA PP  PP
Sbjct: 598 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPP 657

Query: 300 LRSGPPLGAGSRPRALCPAQTPSQASSSGGGRG 332
               PP       + + P  +PS  + S GG G
Sbjct: 658 ----PPPPPAPEQQTMPPPGSPSGGAGSPGGLG 686


>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 59/213 (27%), Positives = 75/213 (35%), Gaps = 28/213 (13%)

Query: 139 GKEVPPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGP 198
           G++VP  P    R     P P    R  H  G P +  L G+G   N        G+ G 
Sbjct: 483 GQQVPGFPTAPTRVVIARPTPPQA-RPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQ 541

Query: 199 ---SPLQRLGGSTGEAPRPRNREAHLRR-KPRVGLEPGPHSSLPGGKQETAPPPQPVRTT 254
               P+    G+ G AP P    A             GP    PGG  +  P PQP    
Sbjct: 542 LLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGP---APGGPAQPPPTPQP-SMA 597

Query: 255 QTFFSPLFSSKLGIHGDRAG-------SLTALRPN--------PDLVTVPLTAHPPVHPP 299
              FS L  + LG  G  AG       ++T   P          D +    TA PP  PP
Sbjct: 598 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPP 657

Query: 300 LRSGPPLGAGSRPRALCPAQTPSQASSSGGGRG 332
               PP       + + P  +PS  + S GG G
Sbjct: 658 ----PPPPPAPEQQTMPPPGSPSGGAGSPGGLG 686


>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
          Length = 1132

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 59/213 (27%), Positives = 75/213 (35%), Gaps = 28/213 (13%)

Query: 139 GKEVPPRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGP 198
           G++VP  P    R     P P    R  H  G P +  L G+G   N        G+ G 
Sbjct: 489 GQQVPGFPTAPTRVVIARPTPPQA-RPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQ 547

Query: 199 ---SPLQRLGGSTGEAPRPRNREAHLRR-KPRVGLEPGPHSSLPGGKQETAPPPQPVRTT 254
               P+    G+ G AP P    A             GP    PGG  +  P PQP    
Sbjct: 548 LLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGP---APGGPAQPPPTPQP-SMA 603

Query: 255 QTFFSPLFSSKLGIHGDRAG-------SLTALRPN--------PDLVTVPLTAHPPVHPP 299
              FS L  + LG  G  AG       ++T   P          D +    TA PP  PP
Sbjct: 604 DLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPP 663

Query: 300 LRSGPPLGAGSRPRALCPAQTPSQASSSGGGRG 332
               PP       + + P  +PS  + S GG G
Sbjct: 664 ----PPPPPAPEQQTMPPPGSPSGGAGSPGGLG 692


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 112/437 (25%), Positives = 153/437 (35%), Gaps = 79/437 (18%)

Query: 144  PRPLPAARAAARY-PRPTAGWRRHHSTGQPGAPVLGG--SGTAGNGGQRVSHRGICGPSP 200
            P P P  +AAA   P PT   R    T  PG    G   + TA   G  +       P P
Sbjct: 842  PAPAPGTKAAAPSGPAPTTSIR---FTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPP 898

Query: 201  LQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSP 260
              +   S  +AP P      L  K  V L   P  S+ GG    A  P P+       SP
Sbjct: 899  KAQ-SVSPVQAPPPGGSAQLLPGKVLVPLA-APSMSVRGGG---AGQPLPL------VSP 947

Query: 261  LFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRP-RALCPAQ 319
             FS  +         +  L P P  V+ P    PP+ P    GP     S+P + L P+ 
Sbjct: 948  PFSVPVQNGAQPPSKIIQLTPVP--VSTPSGLVPPLSPATLPGPT----SQPQKVLLPSS 1001

Query: 320  TPSQASSSGGGR----GTSGAGEGHQHLLITYRVLSNLRRTLCSGG--GVASMRISVGRG 373
            T      S GG     GTS A       + +Y   S++     S G  G A ++  +  G
Sbjct: 1002 TRITYVQSAGGHALPLGTSPASS-QAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAG 1060

Query: 374  LR----------------------AGPRAPDAGSFWD--PNPQTLAPHPQASRRPRA--- 406
                                    A P  P   +F+   P P + AP  Q S+ P +   
Sbjct: 1061 QAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVY 1120

Query: 407  GCSLSLQPPHQRGLRDGCPS-AAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAEL 465
              + S  PP    L  G P+ A    +P  P PS    ++   + A  ++RP P  P ++
Sbjct: 1121 TVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKV 1180

Query: 466  N--------------------PATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPR 505
                                 PA   P   GP+R     +S      T  +P P+P    
Sbjct: 1181 KAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWT 1240

Query: 506  PRTSASRPGPSPHLEAT 522
            P   +S P P P  E T
Sbjct: 1241 PTARSSPPLPPPAEERT 1257



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 66/255 (25%), Positives = 89/255 (34%), Gaps = 55/255 (21%)

Query: 289 PLTAHPP--VHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGG-GRGTSGAGEGHQHLLI 345
           PL   PP    PP+  G   G+     A  PA + + A++S   G GT  A E       
Sbjct: 509 PLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQES------ 562

Query: 346 TYRVLSNLRRTLCSGGGVASMRISVGRGLRAG---PRAPDAGSFWDPNPQT--LAPHPQA 400
                                    G+G  AG   P  P AG    P+  T  L   P  
Sbjct: 563 -------------------------GQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPAT 597

Query: 401 SRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPP 460
            RR R      L+PP    +    PS  G +   L  P  +E   G    ARV     P 
Sbjct: 598 FRRKRPESVGGLEPPGPSVIA-APPSGGGNILQTLVLPPNKEEQEGG--GARV-----PS 649

Query: 461 TPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLE 520
            PA   P+ +   P  PL   A    +       ++P PI ++P P +  +   P+   +
Sbjct: 650 APA---PSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPN---D 703

Query: 521 ATGTHAGSGTCQGSR 535
             G     GT  GSR
Sbjct: 704 TAGARTEMGT--GSR 716



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 88/364 (24%), Positives = 115/364 (31%), Gaps = 83/364 (22%)

Query: 179 GSGT--AGNGGQRVSHRGICGPSPLQRLGGSTGEAPR--PRNREAHLRRKPRV--GLEPG 232
           GSGT  A   GQ  +   +  P P      +  +A R  P +     R++P    GLEP 
Sbjct: 553 GSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEP- 611

Query: 233 PHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTA 292
                PG     APP       QT   P    +    G R  S  A              
Sbjct: 612 -----PGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPA-------------- 652

Query: 293 HPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSN 352
                P L  G P    SRP A          SS+               + I  +    
Sbjct: 653 -----PSLAYGAPAAPLSRPAATMVTNVVRPVSSTP--------------VPIASKPFPT 693

Query: 353 LRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLA---PHPQASRRPRAGCS 409
             R   S    A  R  +G G R    +P   S    + ++ A   P P     P  G +
Sbjct: 694 SGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLG-T 752

Query: 410 LSLQPPHQRGLRDGCPSAAGRLSPALP-----APSPREVTLGSHVPARVSRRPCPPTPAE 464
           +   P     L  G P       PA+      AP     T GS   A             
Sbjct: 753 VGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGG-TTAGSGAGA------------- 798

Query: 465 LNPATSSPRPLGPLRPRAGGQSSG----------HPDRTVTSPRPIPARPRPRTSASRP- 513
                + P PLG L+P A G++ G           P +   +P P PA   P T A+ P 
Sbjct: 799 -GSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPA---PGTKAAAPS 854

Query: 514 GPSP 517
           GP+P
Sbjct: 855 GPAP 858



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 26/100 (26%), Positives = 35/100 (35%), Gaps = 22/100 (22%)

Query: 435  LPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTV 494
            + A +P E   G+  P      P PP          +P P G   P +    SG    T 
Sbjct: 1519 MQAATPTEQPPGAEAP-----LPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSG----TA 1569

Query: 495  TSPRPIPARPRPRTSASRPG-----------PSPHLEATG 523
             +  P+P  P P +   +PG           P P   ATG
Sbjct: 1570 QAAPPLP--PPPESGPGQPGWEGAPQPSPPPPGPSTAATG 1607


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 115/440 (26%), Positives = 149/440 (33%), Gaps = 79/440 (17%)

Query: 126 AKSRRGKVLLEGTGKEVP-PRPLPAARAA--ARYPRPTAGWRRHHSTGQPGAPVLGGSGT 182
           A +RR +      G EV  PRP P+AR       PR +      HST +P +P      +
Sbjct: 166 AMARRSRA----AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP-SPAARRRPS 220

Query: 183 AGNGGQRVSHRGICGPS-PLQ---RLGGSTGEAPRPRNREAHLRRKPRVGLEP------- 231
           AG G QR + R +   + PL    R G S    PR     +  + K    L P       
Sbjct: 221 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 280

Query: 232 -------GPHSSLPGGKQETAPPPQPVR--TTQTFFSPLFS----SKLGIHGDRAGSLTA 278
                  GP SS P      + PP P    + QT  SP  +    +   +      +  +
Sbjct: 281 KDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 340

Query: 279 LRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRA---LCPAQTPSQASSSGGGRGTSG 335
             P+P L   PL   PP  PP  + PPL A   P A   L P  TPS  + +        
Sbjct: 341 FLPSPPLS--PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA----- 393

Query: 336 AGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGR--------GLRAGP-RAPDAGSF 386
                 HLL                   AS  +S            L A P + P +   
Sbjct: 394 -----VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 448

Query: 387 WDPNPQTLAPHPQASRRPRAGCSLSL-QPPHQRGLRDGCPSAAGRLSPALPAPSPREVTL 445
             P   +  P PQA   P A   L L +PP Q       P      SP    P     + 
Sbjct: 449 SPPMSPSATPPPQAP-PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507

Query: 446 GSHVPARVSRRPCPPTPAEL--------NPATSSPRPLGPLRPRAGGQSSGHPDRTVTSP 497
            + +P      P P  P  L            +SP    P RP   G     PD +V+ P
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-----PDTSVSGP 562

Query: 498 RPIPARPRPRTSASRPGPSP 517
           R         T A  PGP P
Sbjct: 563 R--------LTLALAPGPPP 574



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 68/257 (26%), Positives = 80/257 (31%), Gaps = 58/257 (22%)

Query: 281 PNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGH 340
           P+  L   PL   PP  PP+ + P L     P A    Q P +  + G     SG     
Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP---- 562

Query: 341 QHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQA 400
                        R TL                L  GP          P P + +P    
Sbjct: 563 -------------RLTL---------------ALAPGP----------PPPPSRSPSSTL 584

Query: 401 SRRPRAGCSLSL--QPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPC 458
           S    AG S S    P   RG   G P      SP      P +  L +  PA  SR P 
Sbjct: 585 SGPDLAGHSSSATSTPEELRGYDSG-PEGGAAASP------PPDAELAACHPAAWSRGPA 637

Query: 459 PPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPH 518
           PP      P    P P     P  G  S+        +  P  A P P   A  PGPSP 
Sbjct: 638 PPLAFRGAPGAPLPWP-----PATGPGSADGLCTIYETEGPESATPAP--GALDPGPSPG 690

Query: 519 LEATGTHAGSGTCQGSR 535
                  AG+G    SR
Sbjct: 691 TSGGKAAAGAGAGASSR 707



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 74/289 (25%), Positives = 99/289 (34%), Gaps = 64/289 (22%)

Query: 231 PGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPL 290
           PG  +  P G     PP  P        +     K     +RAG +          T+P 
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP--LAERAGGIGG-------ATIPE 72

Query: 291 TAHPPVHPPLRSGPPLGAGSRPRALCPAQ--TPSQASSSGGGRGTSGAGE-GHQHLLITY 347
           +A P   P   S PP  A  R     PA+  +P   SS G   GT+  G  G + L I+ 
Sbjct: 73  SA-PRAGPTRTSRPP--ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS- 128

Query: 348 RVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAG 407
                   T+  G    + + S    L AG R   +G    P P T  P P  +RR RA 
Sbjct: 129 -----AEETVARGKATEAPKRSA---LSAGARRDTSG----PTPGT--PSPAMARRSRAA 174

Query: 408 CSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNP 467
                      G   G P  A    P  P   PR+    +                    
Sbjct: 175 -----------GTEVGLPRPAPSARPRPPTEGPRKSVSSAS-----------------EH 206

Query: 468 ATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPS 516
           +T+ P P    RP AGG       R+++S         P +S +R GPS
Sbjct: 207 STTEPSPAARRRPSAGGGLQRPASRSLSS------SATPLSSPARSGPS 249


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 48/159 (30%), Positives = 62/159 (38%), Gaps = 17/159 (10%)

Query: 370 VGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDG--CPSA 427
           V +G   GP+APD+ +   P PQ  A  P     P +  SL    PHQ  L D    PS 
Sbjct: 739 VAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSL----PHQAPLGDSPHLPSP 794

Query: 428 AGRLSPALPAPSPREVTLGSHVPARVSRRPCPP--TPAELNPATSSPRPLGPLRPRAGGQ 485
                P+ P   P+ V   S  P+     PCPP   P  L         LG   P     
Sbjct: 795 HPTRPPSRPPSRPQSV---SRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPP----- 846

Query: 486 SSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLEATGT 524
            + +P  T   P   P RP+ +       P+PHL  + T
Sbjct: 847 -ASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSST 884



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 118/490 (24%), Positives = 165/490 (33%), Gaps = 105/490 (21%)

Query: 46  ASVNSSHLKAGLVPQSHTPGRLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHLPAAALELC 105
           AS   S   AGLV Q +      +A  L   S  GG  AA    TG  S    A A  L 
Sbjct: 276 ASAGVSPQGAGLVIQKNLSA--AVATTLNGNSVFGGAGAAS-APTGTPSGQPLAVAPGLG 332

Query: 106 RAMLLPGTWFSLNRVKESITAKSRRGKVLLEGTGKEVPPRPL-PAARAAARYPRPTAGWR 164
            + L+P     L+R    I  K      +L     ++ P+P  PA         P A   
Sbjct: 333 SSPLVPAPNVILHRTPTPIQPKPAG---VLPPKLYQLTPKPFAPAGATLTIQGEPGA--- 386

Query: 165 RHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPS---------PLQRLGGSTGEAPRPR 215
                 QP AP       AG  GQ V   G   P+         P    G +  + P   
Sbjct: 387 ---LPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGAL 443

Query: 216 NR--EAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRA 273
           ++    HL  +    + P  H  LPG  Q   P    V+  Q       S+     G + 
Sbjct: 444 SKPMSVHLLNQGSSIVIPAQHM-LPGQNQFLLPGAPAVQLPQQL-----SALPANVGGQI 497

Query: 274 GSLTALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGT 333
            +  A      L+  P+  +  +  PL  GP L   S                       
Sbjct: 498 LAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHS----------------------- 534

Query: 334 SGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGR-GLRAGPRAPDAGSFWDPNPQ 392
              G    H+L                   ++  I VG+  L   P +  AGS   P   
Sbjct: 535 ---GAHSAHIL-------------------SAAPIQVGQPALFQMPVSLAAGSL--PTQS 570

Query: 393 TLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPAR 452
             AP   A+     G +L   PP    + +   +  G + PA PA +      G   P  
Sbjct: 571 QPAPAGPAATTVLQGVTL---PPSAVAMLN---TPDGLVQPATPAAAT-----GEAAPV- 618

Query: 453 VSRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASR 512
           ++ +P P  P    PA S+P PLG  +P+A         +   +P P  A P     A+ 
Sbjct: 619 LTVQPAPQAP----PAVSTPLPLGLQQPQA--------QQPPQAPTPQAAAP---PQATT 663

Query: 513 PGPSPHLEAT 522
           P PSP L ++
Sbjct: 664 PQPSPGLASS 673



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 35/127 (27%), Positives = 47/127 (37%), Gaps = 17/127 (13%)

Query: 390 NPQTLAPHP-QASRRPRAGCSLSLQPPHQRGLRDGCPSA---AGRLSPALPAPSPREVTL 445
           NP   AP P Q   RP++       PP          SA   +   S  LPAP+P +  L
Sbjct: 849 NPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQL 908

Query: 446 GSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPR 505
                    + P PP    L P  ++P P  P              + VT+  P PA P+
Sbjct: 909 QFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPP-----------RTFQMVTT--PFPALPQ 955

Query: 506 PRTSASR 512
           P+    R
Sbjct: 956 PKALLER 962



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 58/235 (24%), Positives = 82/235 (34%), Gaps = 44/235 (18%)

Query: 295  PVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITY-RVLSNL 353
            P H PL S  P GA ++P    P   P++     GG G S +        +T+ R  S+L
Sbjct: 1222 PGHGPLSSSAP-GASTQP----PPHLPTKLVIRHGGAGGSPS--------VTWARASSSL 1268

Query: 354  RRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQ 413
              +  S    +S+             A + G    P P    P P  +   R+   L L+
Sbjct: 1269 SSSSSSSSAASSLD------------ADEDG----PMPSRNRP-PIKTYEARSRIGLKLK 1311

Query: 414  PPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPR 473
               + GL     + A  L P    P P      +  P R    P PP   ++N     P 
Sbjct: 1312 IKQEAGLSKVVHNTA--LDPVHQPPPPPATLKVAEPPPRPP--PPPPPTGQMNGTVDHPP 1367

Query: 474  PLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLEATGTHAGS 528
            P  P R   G  ++ H  R       +P R   R +   PG      A     GS
Sbjct: 1368 PAAPERKPLG--TAPHCPR-------LPLRKTYRENVGGPGAPEGTPAGRARGGS 1413


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 84/301 (27%), Positives = 105/301 (34%), Gaps = 40/301 (13%)

Query: 232 GPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNP----DLVT 287
           GP  S  GG+ +  P P+ V        PL  S+    GD AG     RP P    +   
Sbjct: 331 GPEHSKGGGRVDEGPQPRSVEPQDA--GPLERSQ----GDEAGGHGEDRPEPLSPKESKK 384

Query: 288 VPLTAHPPVHPPLRSGPPLGAGSRPRAL-CPAQTPSQASSSGGGRGTSGAGEGHQHLLIT 346
             L       PP   GP   +     AL       SQ S   G +   G   G       
Sbjct: 385 RKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGE------ 438

Query: 347 YRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLA--PHPQASRRP 404
              +   R+ L  G  VA     V +  +    A D+ +      QTLA    P  S  P
Sbjct: 439 --AVQPCRQPL--GARVAD---KVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHP 491

Query: 405 RAGCS---LSLQPPHQRGLRDGCPSAAGRL---SPALPA-PSPREVTLGSHVPARVSRRP 457
           +AG S   +      + G ++G P +       SPA PA   P E    S  P      P
Sbjct: 492 KAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESP--SETPGPRPAGP 549

Query: 458 CPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASR-PGPS 516
               PAE    T  PRP GP    AG + +  P  T       P R  P  S S  PGP 
Sbjct: 550 AGDEPAESPSETPGPRPAGP----AGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPR 605

Query: 517 P 517
           P
Sbjct: 606 P 606



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 102/405 (25%), Positives = 131/405 (32%), Gaps = 82/405 (20%)

Query: 157 PRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRN 216
           P P  G R+    G PG P    S T G           CGP    + GG   E P+PR+
Sbjct: 301 PHPLEGSRKVEEEGSPGDPDHEAS-TQGR---------TCGPEH-SKGGGRVDEGPQPRS 349

Query: 217 REAHLRRKPRVGLEPGP----HSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDR 272
            E           + GP         GG  E  P P          SP  S K  +   R
Sbjct: 350 VEPQ---------DAGPLERSQGDEAGGHGEDRPEP---------LSPKESKKRKLELSR 391

Query: 273 AGSLTALRPNP------DLVTVPLTAHPPVHPPLRSGPPLGAGSRP-RALCPAQTPSQAS 325
                   P P      + + + L         LR+G     G  P  A+ P + P  A 
Sbjct: 392 REQ-PPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGAR 450

Query: 326 SSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGG----------GVASMRISVGRGLR 375
            +   R      EG      +  V S   +TL   G          G +   +      R
Sbjct: 451 VADKVRKRRKVDEGAGD---SAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGR 507

Query: 376 AGPRAPDAGSFWD-PNPQTLAP-------HPQASRRPR----AGCSLSLQPPHQRGLRDG 423
            GP+    GS  + P P    P        P  +  PR    AG   +  P    G R  
Sbjct: 508 TGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA 567

Query: 424 CPSAAGRL-SPA-LPAPSPREVTLG------SHVPARVSRRPCPPTPAELNPATSSPRPL 475
            P+      SP+  P PSP   T        S  P      P    PAE    T  PRP 
Sbjct: 568 GPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPA 627

Query: 476 GPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLE 520
           GP    AG + +  P  T   P P PA P  R   ++ G +  L+
Sbjct: 628 GP----AGDEPAESPSET---PGPSPAGP-TRDEPAKAGEAAELQ 664


>gi|113429443 PREDICTED: transmembrane protein 46-like [Homo
           sapiens]
          Length = 492

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 108/397 (27%), Positives = 138/397 (34%), Gaps = 95/397 (23%)

Query: 144 PRPLPAARAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRVSHRGI---CGPSP 200
           PR L  +R +  Y  P   W +   TG+P A     +     G +R SH  +   CG + 
Sbjct: 98  PRRLDQSRCS-NYDTPA--WVQ---TGRPPARARDTAAPRDPGRER-SHTAVYAVCGVAA 150

Query: 201 LQRLGG-----STGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQ 255
           L  L G         A  PR R    R    +  +PGP   LP     T  PP       
Sbjct: 151 LLVLAGIGARLGLERAHSPRARRTVTRALTELLKQPGPQEPLP----PTLGPP------- 199

Query: 256 TFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGPP-LGAGSRPRA 314
                    ++G    R     +  P    +     A PP  P +R  PP L A +  R 
Sbjct: 200 --LGGCVQVQMGDGLPRGSPHNSAGPRTPRLA---RASPPGEPFMRVAPPGLAAAAAARD 254

Query: 315 LCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGL 374
             P   P          G  G GE         R+ S  R      G   S R + GRGL
Sbjct: 255 SEPGPVP----------GAGGCGED--------RLGSQPRP---ENGPPGSHRTASGRGL 293

Query: 375 RAGPR----------------APDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQR 418
           R G                  APD     +    + AP P    R + G SL+LQP + +
Sbjct: 294 RRGDSEGGVNRGIGPSRVSLLAPDKKRLNNAPRGSAAPGPPRGPRLQGGGSLTLQPDYAK 353

Query: 419 ---------GLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPAT 469
                       +  P    +  PAL  PSPR+       PAR + RP P  PA L+   
Sbjct: 354 YATFKAAALKAAEAAPRDFCQRFPAL-EPSPRQ------PPAR-APRPSPDLPAPLDACP 405

Query: 470 SSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRP 506
            +P    P  P A G     P    TS R  PARP P
Sbjct: 406 WAPPVYAP--PAAPG-----PYAAWTSSR--PARPAP 433


>gi|239755634 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 449

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 79/295 (26%), Positives = 101/295 (34%), Gaps = 56/295 (18%)

Query: 264 SKLGIHGDRAGSLTALRPNPD---LVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQT 320
           S LG+ GD   +L  L P P     ++V L   P   P   S     AG  P +  PA+ 
Sbjct: 83  SGLGVPGDSESALGLLEPGPPKSLRISVTLGQAPRAGPSAASS--AAAGKTPPSRVPAEP 140

Query: 321 PSQASSS-------------GGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVA--- 364
            S+  +S               GRG +GA  G    L T R      R    G   A   
Sbjct: 141 SSRRGASKRRESWRTDGERLRSGRGCAGAARGPDASLDTRR--EGWPRAAVVGRHEARRL 198

Query: 365 SMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDG- 423
              +SV   L  GP    + S  +   ++ A H ++S R    C    Q P QR L  G 
Sbjct: 199 KPGVSVSSSLSPGPPLQRSSSL-NETLRSAAAHAESSARE---CGKRTQRPEQRFLCRGS 254

Query: 424 --CPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPR 481
             C     RL P  P P                RRP  P PA    A  + R  G   P 
Sbjct: 255 SFCGHRPQRLHPGRPLPP--------------QRRPPGPAPA----AAGATR--GTAAPP 294

Query: 482 AGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLEATGTHAGSGTCQGSRG 536
               S+   D     P P+ AR      +  P  +  L   G  AG G  +   G
Sbjct: 295 GRDPSAWFLDSASACPTPLAAR------SWHPFVANKLCGRGKGAGGGASRPKEG 343



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 26/143 (18%)

Query: 399 QASRRPRAGCSLSLQPPHQRG-----LRDGCPSAAGRLSPALPAPSPREVTLGSHVPARV 453
           +A RRP  G        H RG      RD     +      L  P   E  LG   P   
Sbjct: 51  RAERRPARG-------KHVRGGGVGGCRDSRAGGSHAAPSGLGVPGDSESALGLLEPG-- 101

Query: 454 SRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRP 513
                PP    ++             PRAG  ++       T P  +PA P  R  AS+ 
Sbjct: 102 -----PPKSLRISVTLGQA-------PRAGPSAASSAAAGKTPPSRVPAEPSSRRGASKR 149

Query: 514 GPSPHLEATGTHAGSGTCQGSRG 536
             S   +     +G G    +RG
Sbjct: 150 RESWRTDGERLRSGRGCAGAARG 172


>gi|239749482 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 195

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 48/155 (30%), Positives = 55/155 (35%), Gaps = 13/155 (8%)

Query: 361 GGVASMRISVGRGLRAGPRAPD----AGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPH 416
           GG A  R+ VG G   G   P             P   A HP A R   A   LS     
Sbjct: 16  GGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAA 75

Query: 417 QRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLG 476
           Q   R   P   G    A P P   +      VPA  S  P P  P+   P  S P   G
Sbjct: 76  QPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPS--G 133

Query: 477 PLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSAS 511
           P RP         P   + +PRP  ARP P+ S +
Sbjct: 134 PHRPVL-------PPSALAAPRPPLARPLPQGSVT 161


>gi|239744429 PREDICTED: hypothetical protein XP_002343157 [Homo
           sapiens]
          Length = 449

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 79/295 (26%), Positives = 101/295 (34%), Gaps = 56/295 (18%)

Query: 264 SKLGIHGDRAGSLTALRPNPD---LVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCPAQT 320
           S LG+ GD   +L  L P P     ++V L   P   P   S     AG  P +  PA+ 
Sbjct: 83  SGLGVPGDSESALGLLEPGPPKSLRISVTLGQAPRAGPSAASS--AAAGKTPPSRVPAEP 140

Query: 321 PSQASSS-------------GGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVA--- 364
            S+  +S               GRG +GA  G    L T R      R    G   A   
Sbjct: 141 SSRRGASKRRESWRTDGERLRSGRGCAGAARGPDASLDTRR--EGWPRAAVVGRHEARRL 198

Query: 365 SMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDG- 423
              +SV   L  GP    + S  +   ++ A H ++S R    C    Q P QR L  G 
Sbjct: 199 KPGVSVSSSLSPGPPLQRSSSL-NETLRSAAAHAESSARE---CGKRTQRPEQRFLCRGS 254

Query: 424 --CPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPR 481
             C     RL P  P P                RRP  P PA    A  + R  G   P 
Sbjct: 255 SFCGHRPQRLHPGRPLPP--------------QRRPPGPAPA----AAGATR--GTAAPP 294

Query: 482 AGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLEATGTHAGSGTCQGSRG 536
               S+   D     P P+ AR      +  P  +  L   G  AG G  +   G
Sbjct: 295 GRDPSAWFLDSASACPTPLAAR------SWHPFVANKLCGRGKGAGGGASRPKEG 343



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 26/143 (18%)

Query: 399 QASRRPRAGCSLSLQPPHQRG-----LRDGCPSAAGRLSPALPAPSPREVTLGSHVPARV 453
           +A RRP  G        H RG      RD     +      L  P   E  LG   P   
Sbjct: 51  RAERRPARG-------KHVRGGGVGGCRDSRAGGSHAAPSGLGVPGDSESALGLLEPG-- 101

Query: 454 SRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRP 513
                PP    ++             PRAG  ++       T P  +PA P  R  AS+ 
Sbjct: 102 -----PPKSLRISVTLGQA-------PRAGPSAASSAAAGKTPPSRVPAEPSSRRGASKR 149

Query: 514 GPSPHLEATGTHAGSGTCQGSRG 536
             S   +     +G G    +RG
Sbjct: 150 RESWRTDGERLRSGRGCAGAARG 172


>gi|239743620 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 48/155 (30%), Positives = 55/155 (35%), Gaps = 13/155 (8%)

Query: 361 GGVASMRISVGRGLRAGPRAPD----AGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPH 416
           GG A  R+ VG G   G   P             P   A HP A R   A   LS     
Sbjct: 16  GGGAGRRVRVGVGEPGGFCLPGPALVVAGLDGIRPAPAAAHPPAPRERPAAARLSALAAA 75

Query: 417 QRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLG 476
           Q   R   P   G    A P P   +      VPA  S  P P  P+   P  S P   G
Sbjct: 76  QPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVPAAPSPGPLPARPSSPPPRPSLPS--G 133

Query: 477 PLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSAS 511
           P RP         P   + +PRP  ARP P+ S +
Sbjct: 134 PHRPVL-------PPSALAAPRPPLARPLPQGSVT 161


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 44/148 (29%), Positives = 62/148 (41%), Gaps = 28/148 (18%)

Query: 391 PQTLAPHPQASRRPR--AGCSLSLQPPHQRGLRDGCPSAA---GRLSPALPAPSPREVTL 445
           P+T AP    +RR +  A    ++ PP   G R   P+     G  SP  P   PR + +
Sbjct: 552 PETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRL-V 610

Query: 446 GSHV---------------PARVSRRPCPPTPAELNPATSSPRPLGPLRPR-----AGGQ 485
           GS +               PAR   R  P +P+  +P  +SP P+    P      A   
Sbjct: 611 GSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATA 670

Query: 486 SSGHPDRT--VTSPRPIPARPRPRTSAS 511
             G P+    V +P  IP +PRPR+ AS
Sbjct: 671 EGGAPEAISGVPTPPAIPPQPRPRSLAS 698



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 29/95 (30%), Positives = 36/95 (37%), Gaps = 16/95 (16%)

Query: 425 PSAAGRLSPALPAPSPREV-TLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAG 483
           P+ A   +PA PAP+P     L S      +    PP PA      S P    P+     
Sbjct: 505 PTPATTPAPA-PAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVE---- 559

Query: 484 GQSSGHPDRTVTSPRPIPARPR---PRTSASRPGP 515
                  D    + RP PARP    P+ S SR  P
Sbjct: 560 -------DMARRTKRPAPARPTMPPPQVSGSRSSP 587


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 104/405 (25%), Positives = 139/405 (34%), Gaps = 76/405 (18%)

Query: 156 YPRPTAGWRRHHSTGQPGA-PVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRP 214
           YP P A     HS G P A P L  S + G+      H G  GPS L    G  GEA  P
Sbjct: 514 YPGPAA-----HSQGLPTASPSL--SYSTGHSPALSGHGGGWGPSSL----GGGGEAS-P 561

Query: 215 RNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAG 274
            +    L+  P  G  PG  S    GK  ++     V  +  F +P      G +   AG
Sbjct: 562 SHIIRPLQSPPATGRPPGVGSPGAPGKYLSS-----VLASAPFLAP---PGAGSYAAGAG 613

Query: 275 SLTALRPNPDLVTVPLTAHPPV-----------HPPLRSGPPLGAGSRPRALCPAQTPSQ 323
                    +L+  P    PP            H      PP  +G+    L      + 
Sbjct: 614 GYKGKGDGSELLAGP--GGPPAERTEDEEFLIQHLLQAPSPPRTSGAD--GLVGEDGAAD 669

Query: 324 ASSSGGGRGTSGAGEGHQHLLIT-----YRVLSNLRRTLC-SGGGVASMRISVGRGLRAG 377
           AS   GG G +G   G  + L       Y + S +R +     G  A++ + +GR L+  
Sbjct: 670 ASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGR-LKEK 728

Query: 378 PRAPDAGS-----------FWDPNPQTLAPHPQASRRPRAGCSLSLQP-PHQRGLRDGCP 425
            + P+ G             +    + L    Q S  P    + S QP PH   L  G P
Sbjct: 729 KKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGP 788

Query: 426 SAAGRLSPA-----------LPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRP 474
                L P             P+PSP    +G H+    +R   P  P    P    P P
Sbjct: 789 DLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPP----PPPPPPPP 844

Query: 475 LGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHL 519
             PL+  A  +S G        P     R RP  S   PG    L
Sbjct: 845 PMPLQLEAHLRSHG------LEPAAPSPRLRPEESLDPPGAMQEL 883



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 108/443 (24%), Positives = 146/443 (32%), Gaps = 85/443 (19%)

Query: 149 AARAAARYPRP-TAGWRRHHSTGQPGAPVLGG--SGTAGNGGQRVSH---RGICGPSPL- 201
           AA  A R P P +    +  S G P A    G  SG  G GGQ  S    +G+ GP    
Sbjct: 399 AAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYG 458

Query: 202 QRLGGS-----------TGEAPRP------------RNREAHLRRKPRVGLEPGPHSSLP 238
           Q  GG            +G  P+P            ++      +    G++  P+   P
Sbjct: 459 QGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPG-P 517

Query: 239 GGKQETAPPPQPVRTTQTFFSPLFS--------SKLGIHGDRAGSLTALRPNPDLVTVPL 290
               +  P   P  +  T  SP  S        S LG  G+ + S   +RP   L + P 
Sbjct: 518 AAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPS-HIIRP---LQSPPA 573

Query: 291 TAHPP-VHPPLRSGPPLGA--GSRPRALCPAQTPSQASSSGGGRGTSG-----AGEGH-- 340
           T  PP V  P   G  L +   S P  L P    S A+ +GG +G        AG G   
Sbjct: 574 TGRPPGVGSPGAPGKYLSSVLASAP-FLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPP 632

Query: 341 -----------QHLLITYRVLSNLRRTLCSG--GGVASMRISVGRGLRAGPRAPDAGSFW 387
                      QHLL   +  S  R +   G  G   +   S G G   G   P    + 
Sbjct: 633 AERTEDEEFLIQHLL---QAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYE 689

Query: 388 DPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGL-----RDGCPSAAGRLSPALPAPSPRE 442
                    H Q+  R  A          + GL     +   P   G     L       
Sbjct: 690 LAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHY 749

Query: 443 VTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPA 502
                 + A + + P PP P      ++ P P G L        +G PD  +  P P P 
Sbjct: 750 GAGAKELGAFLQKSPPPPPPTA---QSTQPTPHGLLL------EAGGPDLPLVLPPP-PP 799

Query: 503 RPRPRTSASRPGPSPHLEATGTH 525
           +  P   +  P PSP     G H
Sbjct: 800 QLLPSVLSHAPSPSPSASKVGVH 822



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 41/163 (25%), Positives = 54/163 (33%), Gaps = 25/163 (15%)

Query: 378  PRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSP---- 433
            P  P  G    P      PHP  S     G   +L+     GL  GCPS   RL      
Sbjct: 1315 PSVPARGLQPQPPATPAVPHPPPSGA--FGLGGALEAAESEGLGLGCPSPCKRLDEELKR 1372

Query: 434  ---ALPAPSPREVT-------LGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAG 483
                LP+ S  E         L   + + +S    PP     + +T    PL P     G
Sbjct: 1373 NLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG 1432

Query: 484  ---------GQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSP 517
                       S+G P+  +   +P P  P   T   +P P P
Sbjct: 1433 PPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPP 1475



 Score = 33.9 bits (76), Expect = 0.38
 Identities = 28/115 (24%), Positives = 40/115 (34%), Gaps = 8/115 (6%)

Query: 411  SLQPPHQRGLRDGCPSAAGRLSPALPAPSPREV-------TLGSHVPARVSRRPCPPTPA 463
            +L  P   G +D        L+PA   P P  +       + G+  P  +  +P P  P 
Sbjct: 1404 ALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPP 1463

Query: 464  ELNPATSSPRPLGPLRPRAGGQSS-GHPDRTVTSPRPIPARPRPRTSASRPGPSP 517
               P    P P  P +P          P  +   P P+P  P P   +  P P P
Sbjct: 1464 APTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP 1518



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 78/316 (24%), Positives = 108/316 (34%), Gaps = 55/316 (17%)

Query: 232 GPHSSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLT 291
           GP  + P       PPP P R   T F+ L SS        A +  A + +P L      
Sbjct: 220 GPAQTPPYRPGPPDPPPPP-RHLPTQFNLLASSS-------AAAAAAEQSSPQLYNFSGA 271

Query: 292 AHPPVHPPLRSGPP----LGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLI-- 345
           A  P  PP R+ P     +    RP +  P   P  A +              QH L   
Sbjct: 272 APGPP-PPERALPRQDTVIKHYQRPASAQPPPPPPPAHAL-------------QHYLSCG 317

Query: 346 -TYRVLSNLRRTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRP 404
            +Y  + +     CS  G        G   +AGP    AG+         A  P+A+   
Sbjct: 318 GSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGA------SGRATGPEAAGGG 371

Query: 405 RAGCSLS-----LQPPHQRGLRDGCPSAAG---RLSPALPAPSPREVTLGSHVPARVSRR 456
            AG         +Q P  +  + G  +AAG   R  P     +P+  +LG    A  + +
Sbjct: 372 GAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGK 431

Query: 457 PCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPS 516
                 A    A S  +P G L P+A GQ  G       S  P  +   P+  +  P P 
Sbjct: 432 ASGAGGAG-GQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPP- 489

Query: 517 PHLEATGTHAGSGTCQ 532
                     G  TCQ
Sbjct: 490 ----------GLATCQ 495



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 58/243 (23%), Positives = 77/243 (31%), Gaps = 27/243 (11%)

Query: 282  NPDLVTVPLTAHPPVHPPLRSGPPLGA-GSRPRA----LCPAQTPSQASSSGGG-RGTSG 335
            +P L    LT  PP+ PP    P + A G +P+       P   PS A   GG       
Sbjct: 1295 HPPLYQAGLT--PPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAES 1352

Query: 336  AGEGHQHLLITYRVLSNLRRTLCSGGGVAS-----------MRISVGRGLRAGPRAPDAG 384
             G G        R+   L+R L +    +S           ++ S+   + A    P AG
Sbjct: 1353 EGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAG 1412

Query: 385  --SFWDPNPQTLAPH------PQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALP 436
                  P+   LAP       P     P A  + + +PP         P  A    P  P
Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP 1472

Query: 437  APSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTS 496
             P P         P  V+  P  P P  L P      P  P  P         P     +
Sbjct: 1473 PPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAA 1532

Query: 497  PRP 499
            P P
Sbjct: 1533 PSP 1535


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 119/543 (21%), Positives = 190/543 (34%), Gaps = 71/543 (13%)

Query: 6    LGEEQLPLVPGDKWTLKKKLDSLSPSHIVRDEMTSPDPD--PASVNSSHLKAGLVPQSHT 63
            L   + P +P    T     DS +P+      + SP     P++VN +  +    P  + 
Sbjct: 2242 LASARTPAIP----TAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNL 2297

Query: 64   PG-RLVLAVLLQSLSPEGGLRAAEHRGTGAWSPHLPAAA-------LELCRAMLLPGTWF 115
             G R   A+   SL+  G    A +  + + +P  PA+A             + + G+  
Sbjct: 2298 AGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRT 2357

Query: 116  SLNRVKESITAKSRRGKVLLEGTGKEVPPRPLPA-ARAAARYPRPTAGWRRHHSTGQPGA 174
            +      S+T  S R    L G     P  PL A  R + R   P     R  S   P A
Sbjct: 2358 AAALAPASLT--SARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLD--RARSRTPPSA 2413

Query: 175  PVLGGSGTAGNGGQRVSHRGICGPSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPH 234
            P         +  +  S R    PSP  R+G +  ++  P  ++     +PR    P P 
Sbjct: 2414 P---------SQSRMTSERA---PSPSSRMGQAPSQSLLPPAQD-----QPR---SPVP- 2452

Query: 235  SSLPGGKQETAPPPQPVRTTQTFFSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHP 294
            S+     +       PV  +Q+  S   ++     GD  G L+        V  P   H 
Sbjct: 2453 SAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS--------VPAPGVPHS 2504

Query: 295  PVHPPLRSGPPLGAGSRPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLR 354
             V  P    P      +P AL   Q   +  SS     +S +              S+  
Sbjct: 2505 DVGEP----PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS------------SSSS 2548

Query: 355  RTLCSGGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQP 414
             +  S    +S   S G  L   P  P+      P+P T AP  +A R  R       + 
Sbjct: 2549 SSSSSSSSGSSSSDSEGSSL---PVQPEVALKRVPSP-TPAPK-EAVREGRPPEPTPAKR 2603

Query: 415  PHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRP 474
              +        S++   S +  + S    +  S   +  S     P+PA+  P  + P+P
Sbjct: 2604 KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ-ALPKP 2662

Query: 475  LGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPH-LEATGTHAGSGTCQG 533
              P +P  G + S  P + + S R   +         RP P P   +   + +  G+ +G
Sbjct: 2663 ASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG 2722

Query: 534  SRG 536
             RG
Sbjct: 2723 QRG 2725



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 42/149 (28%), Positives = 62/149 (41%), Gaps = 20/149 (13%)

Query: 378  PRAPDAGSFWDPNPQTLAPHPQASRRPRAGCS--LSLQP---PHQRGLRDGCPSAAGRLS 432
            P+   +GS    + +T+A  P   +R R+G S  L ++P   P +R   D  P +  +  
Sbjct: 1512 PQRERSGSESSVDQKTVARTP-LGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTR 1570

Query: 433  PALP----APSPREVTLGSHVPARVSRRPCPPTPAELNPATSSPRPLGPLRPRAGGQSSG 488
              L     + S  EV   S +  R SR    P   +       PR      PRA   S  
Sbjct: 1571 TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD------KPRAA----PRAQSGSDS 1620

Query: 489  HPDRTVTSPRPIPARPRPRTSASRPGPSP 517
             P+    +PR +P R R  +S+   GPSP
Sbjct: 1621 SPEPKAPAPRALPRRSRSGSSSKGRGPSP 1649



 Score = 37.0 bits (84), Expect = 0.045
 Identities = 85/350 (24%), Positives = 133/350 (38%), Gaps = 56/350 (16%)

Query: 198  PSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQ-ETAPPPQPVRTT-- 254
            PS   R G S G          H       G++  P +   G  + +++P P+ +  T  
Sbjct: 1435 PSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR 1494

Query: 255  ---QTFFSPLFSSK-LGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGS 310
               ++  SP  ++K L    +R+GS +++    D  TV   A  P+    RSG      S
Sbjct: 1495 PRSRSPSSPELNNKCLTPQRERSGSESSV----DQKTV---ARTPLGQRSRSG-----SS 1542

Query: 311  RPRALCPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISV 370
            +   + P+ +P + S S     +S   +      +  R  S     + S   ++  R   
Sbjct: 1543 QELDVKPSASPQERSESD----SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS 1598

Query: 371  GRG--LRAGPRA-PDAGSFWDPNPQTLAPHPQA-SRRPRAGCSLSLQ------------- 413
            G    ++  PRA P A S  D +P+  AP P+A  RR R+G S   +             
Sbjct: 1599 GSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS 1658

Query: 414  ---PPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVP--ARVSRRP-----CPPTPA 463
               PP  R  R G  S+    + +   P  R       +   AR+SRR       P T +
Sbjct: 1659 PEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS 1718

Query: 464  EL------NPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPRPIPARPRPR 507
                    +P+ SSP P    R     +S+  P    TS R     P+PR
Sbjct: 1719 RTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR 1768



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 42/163 (25%), Positives = 69/163 (42%), Gaps = 26/163 (15%)

Query: 380 APDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQP--PHQRGLRDGCPSAAGRLSPAL-- 435
           +P +G   + +     P   +++RP +  + + QP  P++   +D    +A R SP+   
Sbjct: 297 SPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPER 356

Query: 436 -------PAPSP--REVTLGSHVP---ARVSRRPCPPTPAELNPATSSPRPLGPLR-PRA 482
                  PAP+P   E   GS  P     +S+ P  P P+E +P      P  P + P++
Sbjct: 357 SSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP-PSEASPTRDRSPPKSPEKLPQS 415

Query: 483 GGQSSGHPDRTVTSPRPIPARPRPRTSASRPGPSPHLEATGTH 525
               S  P     SP+P        +S   P P+P   A G+H
Sbjct: 416 SSSESSPP-----SPQPTKVSRHASSSPESPKPAP---APGSH 450



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 90/355 (25%), Positives = 109/355 (30%), Gaps = 59/355 (16%)

Query: 198 PSPLQRLGGSTGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTF 257
           PSP +   G    AP P   E H       G  P P ++ P   QE   PP     T+  
Sbjct: 352 PSPERSSTGPEPPAPTPLLAERH-------GGSPQPLATTPLS-QEPVNPPSEASPTRDR 403

Query: 258 FSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAH-----------PPVHPPLRSGPPL 306
             P    KL     ++ S  +  P+P    V   A            P  H  + S P  
Sbjct: 404 SPPKSPEKL----PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTS 459

Query: 307 GAGSRPRAL---CPAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLR----RTLCS 359
              S  RA      + TPS+         T+  G        T R  S  R    R   S
Sbjct: 460 KNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTP-TKRGHSRSRSPQWRRSRS 518

Query: 360 GGGVASMRISVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRG 419
                  R    RG    P+ P     W  +  T       SR  R G S S  P  +  
Sbjct: 519 AQRWGRSRSPQRRGRSRSPQRPG----WSRSRNT--QRRGRSRSARRGRSHSRSPATRGR 572

Query: 420 LRDGCPSAAGRLSPALPAP------SPREVTLGSHVPARVSRRPCPPTPAELNPATSSP- 472
            R   P+  GR     PA       +P      S  PAR  R     TPA     T SP 
Sbjct: 573 SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR-TPARRRSRTRSPV 631

Query: 473 ----RPLGPLR----------PRAGGQSSGHPDRTVTSPRPIPARPRPRTSASRP 513
               R   P R           R G   S  P R   S    PAR   R+ +  P
Sbjct: 632 RRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTP 686



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 35/130 (26%), Positives = 46/130 (35%), Gaps = 15/130 (11%)

Query: 398  PQASRRPRAGCSLSLQPPHQRGLRDGCPSAAGRLSPALPAPSPREVTLGSHVPARVSRRP 457
            P   RR R+  S    P  +R  R   P A  R S +     PR+ +  S  P  + RR 
Sbjct: 2000 PVTRRRSRSRTS----PVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR-SRSPLAIRRRS 2054

Query: 458  CPPTPAELNPATSSPRPLGPLRPRAGGQSSGHPDRTVTSPR----------PIPARPRPR 507
               TP       S  R    +R R+   SS    R+ T P           P+       
Sbjct: 2055 RSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRM 2114

Query: 508  TSASRPGPSP 517
            +  SRP  SP
Sbjct: 2115 SCFSRPSMSP 2124


>gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 255

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 71/256 (27%), Positives = 88/256 (34%), Gaps = 47/256 (18%)

Query: 151 RAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRV--SHRGICGPSPLQRL---- 204
           R + R P+P A      +    G    GG G AG GG  V  +  G C     Q      
Sbjct: 21  RGSQRVPQPPA------ARSPRGPRAGGGGGDAGGGGAPVRRARGGGCWARAYQDARCFG 74

Query: 205 ---GG----STGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTF 257
              GG    S+G    P    A  R   R         S  G +   A P  P R  + F
Sbjct: 75  RGEGGDLQVSSGPGAAP---PAEFRASAR---------SAQGSRDVPAGPGFPPRLPRPF 122

Query: 258 FSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCP 317
            S  FS++  +    A +L A R        P  A P    P   GP  GA  R R    
Sbjct: 123 TSASFSNQTRLRRRSASALPAPR------LCPQRASPGCSSPGVRGPGGGASPRARGGNA 176

Query: 318 AQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAG 377
           A   +   ++GGGR  S    G    L      + L R     G    MR  +G G R  
Sbjct: 177 AAALAARQAAGGGRSRSAFVAGRDAAL----ACAQLPRRPRGAGARRGMRRRLGAGERPA 232

Query: 378 ------PRAPDAGSFW 387
                 PRAP  G+ W
Sbjct: 233 PRPRGPPRAPARGARW 248


>gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo
           sapiens]
          Length = 255

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 71/256 (27%), Positives = 88/256 (34%), Gaps = 47/256 (18%)

Query: 151 RAAARYPRPTAGWRRHHSTGQPGAPVLGGSGTAGNGGQRV--SHRGICGPSPLQRL---- 204
           R + R P+P A      +    G    GG G AG GG  V  +  G C     Q      
Sbjct: 21  RGSQRVPQPPA------ARSPRGPRAGGGGGDAGGGGAPVRRARGGGCWARAYQDARCFG 74

Query: 205 ---GG----STGEAPRPRNREAHLRRKPRVGLEPGPHSSLPGGKQETAPPPQPVRTTQTF 257
              GG    S+G    P    A  R   R         S  G +   A P  P R  + F
Sbjct: 75  RGEGGDLQVSSGPGAAP---PAEFRASAR---------SAQGSRDVPAGPGFPPRLPRPF 122

Query: 258 FSPLFSSKLGIHGDRAGSLTALRPNPDLVTVPLTAHPPVHPPLRSGPPLGAGSRPRALCP 317
            S  FS++  +    A +L A R        P  A P    P   GP  GA  R R    
Sbjct: 123 TSASFSNQTRLRRRSASALPAPR------LCPQRASPGCSSPGVRGPGGGASPRARGGNA 176

Query: 318 AQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRISVGRGLRAG 377
           A   +   ++GGGR  S    G    L      + L R     G    MR  +G G R  
Sbjct: 177 AAALAARQAAGGGRSRSAFVAGRDAAL----ACAQLPRRPRGAGARRGMRRRLGAGERPA 232

Query: 378 ------PRAPDAGSFW 387
                 PRAP  G+ W
Sbjct: 233 PRPRGPPRAPARGARW 248


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 75/322 (23%), Positives = 108/322 (33%), Gaps = 68/322 (21%)

Query: 214 PRNREAHLRRKPRVGLEPGPHSSL--PGGKQETAPPPQPVRTTQTF--------FSPLFS 263
           PR  EA     P V    G H+ +  P  +   APP  P    Q +          P   
Sbjct: 176 PRQPEASFEPHPSV-TPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMG 234

Query: 264 SKLGIHGDRAGSLTALRPNPDLVTVPLTAH-------PPVHPPLRSGPPLGAGSRPRALC 316
            K G      G     + +P   T P++         PP  PP     P+G G+ P A  
Sbjct: 235 PKGGGAASSVGGPNGGKQHPP-PTTPISVSSSGASGAPPTKPPTT---PVGGGNLPSAPP 290

Query: 317 PAQTPSQASSSGGGRGTSGAGEGHQHLLITYRVLSNLRRTLCSGGGVASMRI-------- 368
           PA  P    +                 L     L  L     S  G+ +  +        
Sbjct: 291 PANFPHVTPN-----------------LPPPPALRPLNNASASPPGLGAQPLPGHLPSPH 333

Query: 369 SVGRGLRAGPRAPDAGSFWDPNPQTLAPHPQASRRPRAGCSLSLQPPHQRGLRDGCPSAA 428
           ++G+G+   P  P+ G    P+P +L P   ++  P      S              S++
Sbjct: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSS 393

Query: 429 GRLSP-----ALPA-----PSPREVTLGSHVP----------ARVSRRPCPPTPAELNPA 468
              SP     ALP+     P P  +++ +  P          A  S+ P PP P     A
Sbjct: 394 SSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453

Query: 469 TSSPRPLGPLRPRAGGQSSGHP 490
            S+  P GP  P  G QS+ HP
Sbjct: 454 NSNAHP-GPFPPSTGAQSTAHP 474


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,553,251
Number of Sequences: 37866
Number of extensions: 2210199
Number of successful extensions: 15194
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 144
Number of HSP's successfully gapped in prelim test: 1320
Number of HSP's that attempted gapping in prelim test: 10736
Number of HSP's gapped (non-prelim): 4835
length of query: 536
length of database: 18,247,518
effective HSP length: 107
effective length of query: 429
effective length of database: 14,195,856
effective search space: 6090022224
effective search space used: 6090022224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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