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Search of human proteins with 116734855
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116734855 cysteine-rich with EGF-like domains 1 isoform 3
[Homo sapiens]
(420 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116734855 cysteine-rich with EGF-like domains 1 isoform 3 [Ho... 922 0.0
gi|22095397 cysteine-rich with EGF-like domains 1 isoform 2 [Hom... 922 0.0
gi|72534728 cysteine-rich with EGF-like domains 1 isoform 1 [Hom... 788 0.0
gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Ho... 375 e-104
gi|205360956 cysteine-rich with EGF-like domains 2 isoform a [Ho... 352 4e-97
gi|110347437 latent transforming growth factor beta binding prot... 99 7e-21
gi|110347412 latent transforming growth factor beta binding prot... 99 7e-21
gi|110347431 latent transforming growth factor beta binding prot... 99 7e-21
gi|66346695 fibrillin 2 precursor [Homo sapiens] 94 3e-19
gi|61743980 stabilin 2 precursor [Homo sapiens] 88 2e-17
gi|166362728 epidermal growth factor (beta-urogastrone) [Homo sa... 87 2e-17
gi|24430141 fibrillin 1 precursor [Homo sapiens] 87 4e-17
gi|4557733 latent transforming growth factor beta binding protei... 85 1e-16
gi|61743978 stabilin 1 precursor [Homo sapiens] 81 2e-15
gi|56237021 fibrillin 3 precursor [Homo sapiens] 81 2e-15
gi|51873055 fibulin 2 isoform b precursor [Homo sapiens] 80 5e-15
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 79 6e-15
gi|86788132 EGF-containing fibulin-like extracellular matrix pro... 79 1e-14
gi|86788015 EGF-containing fibulin-like extracellular matrix pro... 79 1e-14
gi|9665262 EGF-containing fibulin-like extracellular matrix prot... 79 1e-14
gi|118572606 hemicentin 1 [Homo sapiens] 78 1e-14
gi|19743803 fibulin 5 precursor [Homo sapiens] 76 5e-14
gi|194328809 latent transforming growth factor beta binding prot... 75 1e-13
gi|18497288 latent transforming growth factor beta binding prote... 75 1e-13
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 75 1e-13
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 75 1e-13
gi|34734066 fibulin 1 isoform D [Homo sapiens] 75 1e-13
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 75 1e-13
gi|88758613 CD93 antigen precursor [Homo sapiens] 73 4e-13
gi|56550049 uromodulin precursor [Homo sapiens] 71 2e-12
>gi|116734855 cysteine-rich with EGF-like domains 1 isoform 3 [Homo
sapiens]
Length = 420
Score = 922 bits (2383), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 1 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL 60
MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
Sbjct: 1 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL 60
Query: 61 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW 120
ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
Sbjct: 61 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW 120
Query: 121 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH 180
FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
Sbjct: 121 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH 180
Query: 181 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH 240
CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
Sbjct: 181 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH 240
Query: 241 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG 300
LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
Sbjct: 241 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG 300
Query: 301 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE 360
SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE
Sbjct: 301 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE 360
Query: 361 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR 420
DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
Sbjct: 361 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR 420
>gi|22095397 cysteine-rich with EGF-like domains 1 isoform 2 [Homo
sapiens]
Length = 420
Score = 922 bits (2383), Expect = 0.0
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 1 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL 60
MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
Sbjct: 1 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL 60
Query: 61 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW 120
ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
Sbjct: 61 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW 120
Query: 121 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH 180
FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
Sbjct: 121 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH 180
Query: 181 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH 240
CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
Sbjct: 181 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH 240
Query: 241 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG 300
LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
Sbjct: 241 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG 300
Query: 301 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE 360
SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE
Sbjct: 301 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE 360
Query: 361 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR 420
DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
Sbjct: 361 DELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR 420
>gi|72534728 cysteine-rich with EGF-like domains 1 isoform 1 [Homo
sapiens]
Length = 422
Score = 788 bits (2036), Expect = 0.0
Identities = 350/361 (96%), Positives = 355/361 (98%)
Query: 1 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL 60
MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL
Sbjct: 1 MAPWPPKGLVPAVLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGL 60
Query: 61 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW 120
ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW
Sbjct: 61 ERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWW 120
Query: 121 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH 180
FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH
Sbjct: 121 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGH 180
Query: 181 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH 240
CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH
Sbjct: 181 CDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHH 240
Query: 241 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG 300
LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG
Sbjct: 241 LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVG 300
Query: 301 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTE 360
SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIP + +++T
Sbjct: 301 SKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPGAFPILTDLTP 360
Query: 361 D 361
+
Sbjct: 361 E 361
>gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Homo
sapiens]
Length = 353
Score = 375 bits (963), Expect = e-104
Identities = 157/313 (50%), Positives = 202/313 (64%), Gaps = 2/313 (0%)
Query: 34 PPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETRLVEV 93
PP +P PCH CRGLVD FN+G+ T + NFGGGNTAWEE+ LSKY+ SE RL+E+
Sbjct: 19 PPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEI 78
Query: 94 LEGVCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCL 153
LEG+C SDFEC+++LE EE +E+WW + E PDLF+W C +LK+CC GT+GP CL
Sbjct: 79 LEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCL 138
Query: 154 PCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSA 213
C GG++RPC G G C G+G+R G G C C GY G C C GYF + RN +H +C+A
Sbjct: 139 ACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTA 198
Query: 214 CFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRD 273
C C CSG +C +C+ GW L CVD+DEC E C A QFC N GSY C +
Sbjct: 199 CDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEE 258
Query: 274 CAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECE--TEVCPGENKQCENTEGGYRCI 331
C +C+GC G GPG CK+C GY + +C DVDEC + C +N+ C NT G Y C+
Sbjct: 259 CDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCV 318
Query: 332 CAEGYKQMEGICV 344
C +G+++ E CV
Sbjct: 319 CPDGFEETEDACV 331
>gi|205360956 cysteine-rich with EGF-like domains 2 isoform a [Homo
sapiens]
Length = 402
Score = 352 bits (903), Expect = 4e-97
Identities = 157/362 (43%), Positives = 202/362 (55%), Gaps = 51/362 (14%)
Query: 34 PPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETRLVEV 93
PP +P PCH CRGLVD FN+G+ T + NFGGGNTAWEE+ LSKY+ SE RL+E+
Sbjct: 19 PPAPEAAKKPTPCHRCRGLVDKFNQGMVDTAKKNFGGGNTAWEEKTLSKYESSEIRLLEI 78
Query: 94 LEGVCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCL 153
LEG+C SDFEC+++LE EE +E+WW + E PDLF+W C +LK+CC GT+GP CL
Sbjct: 79 LEGLCESSDFECNQMLEAQEEHLEAWWLQLKSEYPDLFEWFCVKTLKVCCSPGTYGPDCL 138
Query: 154 PCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCS- 212
C GG++RPC G G C G+G+R G G C C GY G C C GYF + RN +H +C+
Sbjct: 139 ACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSLRNETHSICTV 198
Query: 213 ------------------------------------------------ACFGPCARCSGP 224
AC C CSG
Sbjct: 199 RTGLSDSYPPCCLSLGCWRGVGHAWIRGRNTHTQPGYSSRVWIAAFSPACDESCKTCSGL 258
Query: 225 EESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGA 284
+C +C+ GW L CVD+DEC E C A QFC N GSY C +C +C+GC G
Sbjct: 259 TNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGE 318
Query: 285 GPGRCKKCSPGYQQVGSKCLDVDECE--TEVCPGENKQCENTEGGYRCICAEGYKQMEGI 342
GPG CK+C GY + +C DVDEC + C +N+ C NT G Y C+C +G+++ E
Sbjct: 319 GPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVCPDGFEETEDA 378
Query: 343 CV 344
CV
Sbjct: 379 CV 380
Score = 67.8 bits (164), Expect = 2e-11
Identities = 51/173 (29%), Positives = 65/173 (37%), Gaps = 36/173 (20%)
Query: 151 SCLPCPGGTERPCGGYGQCEGEGTRGGSGHC----DCQAGYGGEACGQCGLGYFEAERNA 206
SC C G T R CG +CE G G C +C A C F N
Sbjct: 251 SCKTCSGLTNRDCG---ECE-VGWVLDEGACVDVDECAA-----EPPPCSAAQFCKNANG 301
Query: 207 SHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANC-GADQFCVNT 265
S+ C C C C+G NC +C G+A H +C D+DEC C ++ C NT
Sbjct: 302 SY-TCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNENCYNT 360
Query: 266 EGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGEN 318
GSY C C G+++ C V E E GE+
Sbjct: 361 PGSYVC-------------------VCPDGFEETEDAC--VPPAEAEATEGES 392
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 99.0 bits (245), Expect = 7e-21
Identities = 80/254 (31%), Positives = 104/254 (40%), Gaps = 59/254 (23%)
Query: 125 QEAPDLFQWLCSD---SLKLCCPAG--TFGPSCLPCPGGTE-----RPCGGYGQCEGEGT 174
QE P C + S CPAG + GP PC E PC YG+CE
Sbjct: 649 QEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGA-PCQDVDECARSPPPCT-YGRCENTE- 705
Query: 175 RGGSGHCDCQAGYGGEACG-QCGLGYFEAERNASHLVCSACFGPCARC-SGPEESNCLQC 232
GS C C G+ G +C + + +HL C P C + P C C
Sbjct: 706 --GSFQCVCPMGFQPNTAGSECE----DVDECENHLAC-----PGQECVNSPGSFQCRTC 754
Query: 233 KKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCK-- 290
G LH +C D+DEC + CG C NTEGS+ C CA G PG C
Sbjct: 755 PSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRC-SCAPGYRAPSGR-PGPCADV 812
Query: 291 ------------------------KCSPGYQ--QVGSKCLDVDEC-ETEVCPGENKQCEN 323
C+PGY+ G+ CLDVDEC E ++C ++ C N
Sbjct: 813 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC--QSGICTN 870
Query: 324 TEGGYRCICAEGYK 337
T+G + CIC G++
Sbjct: 871 TDGSFECICPPGHR 884
Score = 88.6 bits (218), Expect = 1e-17
Identities = 76/243 (31%), Positives = 97/243 (39%), Gaps = 66/243 (27%)
Query: 141 LC-CPAG----TFGPSCLPCPGGTERP--CGGYGQCEGEGTRGGSGHCDCQAGYGGEACG 193
LC CPAG G SC T+ P CG G C+ GS C C AG+ G AC
Sbjct: 586 LCVCPAGYQAAPHGASCQDVDECTQSPGLCGR-GACKN---LPGSFRCVCPAGFRGSACE 641
Query: 194 Q-----------CGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLK 242
+ CG G + + H C A F R GP
Sbjct: 642 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGF----RSRGPGAP--------------- 682
Query: 243 CVDIDECGTEGANCGADQFCVNTEGSYEC------------------RDCAK--ACLG-- 280
C D+DEC C + C NTEGS++C +C AC G
Sbjct: 683 CQDVDECARSPPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQE 741
Query: 281 CMGA-GPGRCKKCSPGYQQVGSKCLDVDECETEVCP-GENKQCENTEGGYRCICAEGYKQ 338
C+ + G +C+ C G+ +C DVDEC + P G + C NTEG +RC CA GY+
Sbjct: 742 CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 801
Query: 339 MEG 341
G
Sbjct: 802 PSG 804
Score = 86.3 bits (212), Expect = 5e-17
Identities = 74/249 (29%), Positives = 89/249 (35%), Gaps = 51/249 (20%)
Query: 135 CSDSLKLCCP-------AGTFGPSCLP---CPGGTERPCGGYGQC-EGEGTRGGSGHCDC 183
CS C P G+F SC P P G PC +C EG+ H +C
Sbjct: 771 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFC---FPHGEC 827
Query: 184 QAGYGGEACGQCGLGYFEAERNASHLVCSACF-------GPCARCSGPEESNCLQCKKGW 236
G AC C GY R AS L C G C G E C +
Sbjct: 828 LNTDGSFAC-TCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAG 886
Query: 237 ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC-RDCAKACLG-----------CMGA 284
C+D+DEC G Q C N+ GSY C RDC C
Sbjct: 887 P-DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY 945
Query: 285 GPGRC---------------KKCSPGYQQV-GSKCLDVDECETEVCPGENKQCENTEGGY 328
GP C C PGYQ G C DVDEC G + C+N G +
Sbjct: 946 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSF 1005
Query: 329 RCICAEGYK 337
+C+C +GY+
Sbjct: 1006 QCLCDQGYE 1014
Score = 63.9 bits (154), Expect = 3e-10
Identities = 61/223 (27%), Positives = 80/223 (35%), Gaps = 47/223 (21%)
Query: 134 LCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRG-GSGHCD---------- 182
+C + ++C P C+ P G C + +GTR C
Sbjct: 481 MCQRNPQVCGPG-----RCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR 535
Query: 183 CQAGYGGEACGQCGLGYFEAERNASHLVCSACFG---PC--ARCSGPEESNCLQCKKGW- 236
C+ G C CG G+ R A L C PC RC S C G+
Sbjct: 536 CENSPGSFRC-VCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 594
Query: 237 -ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPG 295
A H C D+DEC CG C N GS+ C C G
Sbjct: 595 AAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRC-------------------VCPAG 634
Query: 296 YQQVGSKCL-DVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
++ GS C DVDEC E P +C+NT G + C C G++
Sbjct: 635 FR--GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFR 675
Score = 49.7 bits (117), Expect = 5e-06
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 267 GSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEV-CPGENKQCENTE 325
G ++C+ C++ LG C G+++V C DVDEC T C ++ +C NT
Sbjct: 253 GVHDCQLCSER-LGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC--QHGECANTR 309
Query: 326 GGYRCICAEGY--KQMEGICVKEQIPESA 352
GGY C+C +G+ C+ + + A
Sbjct: 310 GGYTCVCPDGFLLDSSRSSCISQHVISEA 338
Score = 43.1 bits (100), Expect = 5e-04
Identities = 28/90 (31%), Positives = 32/90 (35%), Gaps = 21/90 (23%)
Query: 245 DIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSK-- 302
D+DEC CVNT Y C CS GY +
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCY-------------------CSNGYYYHTQRLE 1226
Query: 303 CLDVDECETEVCPGENKQCENTEGGYRCIC 332
C+D DEC E E +C NT G Y C C
Sbjct: 1227 CIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/125 (29%), Positives = 50/125 (40%), Gaps = 20/125 (16%)
Query: 164 GGYGQCE-----GEGTRGGSGHCDCQAGY--------GGEACGQCGLGYFEAERNASHLV 210
G YG+ E G GTR D + + GG G Y E E ++
Sbjct: 1414 GPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGIL 1473
Query: 211 CSACFGPCARCSGPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCG--ADQFCVNTE 266
G C R PE C +C G+ L + CVDI+EC A + C+NT+
Sbjct: 1474 DGCTNGRCVRV--PEGFTC-RCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTD 1530
Query: 267 GSYEC 271
GS+ C
Sbjct: 1531 GSFRC 1535
Score = 40.4 bits (93), Expect = 0.003
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Query: 281 CMGAGPGRCKKCSPGYQ--QVGSKCLDVDECETEVCPGE---NKQCENTEGGYRCICAEG 335
C+ G +C GY+ C+D++EC+ N +C NT+G +RCIC G
Sbjct: 1481 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1540
Query: 336 Y 336
+
Sbjct: 1541 F 1541
Score = 39.7 bits (91), Expect = 0.005
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query: 232 CKKGWALH--HLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
C G+ H L+C+D DEC E C + CVNT GSY C
Sbjct: 1214 CSNGYYYHTQRLECIDNDECADEEPACEGGR-CVNTVGSYHC 1254
Score = 37.7 bits (86), Expect = 0.020
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%)
Query: 210 VCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSY 269
+CS G R S P+ C G+ + C D+DEC T G C + C NT G Y
Sbjct: 259 LCSERLGNSERVSAPDGP----CPTGFERVNGSCEDVDECAT-GGRCQHGE-CANTRGGY 312
Query: 270 EC 271
C
Sbjct: 313 TC 314
Score = 33.5 bits (75), Expect = 0.37
Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 5/35 (14%)
Query: 305 DVDECET---EVCPGENKQCENTEGGYRCICAEGY 336
DVDEC+ +VC ++ C NT GY C C+ GY
Sbjct: 1186 DVDECQLFRDQVC--KSGVCVNTAPGYSCYCSNGY 1218
Score = 33.1 bits (74), Expect = 0.48
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 28/123 (22%)
Query: 134 LCSDSL----KLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGG 189
LCS+ L ++ P G PCP G ER G + T G H +C GG
Sbjct: 259 LCSERLGNSERVSAPDG-------PCPTGFERVNGSCEDVDECATGGRCQHGECANTRGG 311
Query: 190 EACGQCGLGY-FEAERNA--SHLVCSACFGPCAR------CSGPEESN-------CLQCK 233
C C G+ ++ R++ S V S GPC R CS P N C +
Sbjct: 312 YTC-VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG 370
Query: 234 KGW 236
K W
Sbjct: 371 KAW 373
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 99.0 bits (245), Expect = 7e-21
Identities = 80/254 (31%), Positives = 104/254 (40%), Gaps = 59/254 (23%)
Query: 125 QEAPDLFQWLCSD---SLKLCCPAG--TFGPSCLPCPGGTE-----RPCGGYGQCEGEGT 174
QE P C + S CPAG + GP PC E PC YG+CE
Sbjct: 679 QEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGA-PCQDVDECARSPPPCT-YGRCENTE- 735
Query: 175 RGGSGHCDCQAGYGGEACG-QCGLGYFEAERNASHLVCSACFGPCARC-SGPEESNCLQC 232
GS C C G+ G +C + + +HL C P C + P C C
Sbjct: 736 --GSFQCVCPMGFQPNTAGSECE----DVDECENHLAC-----PGQECVNSPGSFQCRTC 784
Query: 233 KKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCK-- 290
G LH +C D+DEC + CG C NTEGS+ C CA G PG C
Sbjct: 785 PSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRC-SCAPGYRAPSGR-PGPCADV 842
Query: 291 ------------------------KCSPGYQ--QVGSKCLDVDEC-ETEVCPGENKQCEN 323
C+PGY+ G+ CLDVDEC E ++C ++ C N
Sbjct: 843 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC--QSGICTN 900
Query: 324 TEGGYRCICAEGYK 337
T+G + CIC G++
Sbjct: 901 TDGSFECICPPGHR 914
Score = 88.6 bits (218), Expect = 1e-17
Identities = 76/243 (31%), Positives = 97/243 (39%), Gaps = 66/243 (27%)
Query: 141 LC-CPAG----TFGPSCLPCPGGTERP--CGGYGQCEGEGTRGGSGHCDCQAGYGGEACG 193
LC CPAG G SC T+ P CG G C+ GS C C AG+ G AC
Sbjct: 616 LCVCPAGYQAAPHGASCQDVDECTQSPGLCGR-GACKN---LPGSFRCVCPAGFRGSACE 671
Query: 194 Q-----------CGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLK 242
+ CG G + + H C A F R GP
Sbjct: 672 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGF----RSRGPGAP--------------- 712
Query: 243 CVDIDECGTEGANCGADQFCVNTEGSYEC------------------RDCAK--ACLG-- 280
C D+DEC C + C NTEGS++C +C AC G
Sbjct: 713 CQDVDECARSPPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQE 771
Query: 281 CMGA-GPGRCKKCSPGYQQVGSKCLDVDECETEVCP-GENKQCENTEGGYRCICAEGYKQ 338
C+ + G +C+ C G+ +C DVDEC + P G + C NTEG +RC CA GY+
Sbjct: 772 CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 831
Query: 339 MEG 341
G
Sbjct: 832 PSG 834
Score = 86.3 bits (212), Expect = 5e-17
Identities = 74/249 (29%), Positives = 89/249 (35%), Gaps = 51/249 (20%)
Query: 135 CSDSLKLCCP-------AGTFGPSCLP---CPGGTERPCGGYGQC-EGEGTRGGSGHCDC 183
CS C P G+F SC P P G PC +C EG+ H +C
Sbjct: 801 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFC---FPHGEC 857
Query: 184 QAGYGGEACGQCGLGYFEAERNASHLVCSACF-------GPCARCSGPEESNCLQCKKGW 236
G AC C GY R AS L C G C G E C +
Sbjct: 858 LNTDGSFAC-TCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAG 916
Query: 237 ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC-RDCAKACLG-----------CMGA 284
C+D+DEC G Q C N+ GSY C RDC C
Sbjct: 917 P-DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY 975
Query: 285 GPGRC---------------KKCSPGYQQV-GSKCLDVDECETEVCPGENKQCENTEGGY 328
GP C C PGYQ G C DVDEC G + C+N G +
Sbjct: 976 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSF 1035
Query: 329 RCICAEGYK 337
+C+C +GY+
Sbjct: 1036 QCLCDQGYE 1044
Score = 63.9 bits (154), Expect = 3e-10
Identities = 61/223 (27%), Positives = 80/223 (35%), Gaps = 47/223 (21%)
Query: 134 LCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRG-GSGHCD---------- 182
+C + ++C P C+ P G C + +GTR C
Sbjct: 511 MCQRNPQVCGPG-----RCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR 565
Query: 183 CQAGYGGEACGQCGLGYFEAERNASHLVCSACFG---PC--ARCSGPEESNCLQCKKGW- 236
C+ G C CG G+ R A L C PC RC S C G+
Sbjct: 566 CENSPGSFRC-VCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 624
Query: 237 -ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPG 295
A H C D+DEC CG C N GS+ C C G
Sbjct: 625 AAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRC-------------------VCPAG 664
Query: 296 YQQVGSKCL-DVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
++ GS C DVDEC E P +C+NT G + C C G++
Sbjct: 665 FR--GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFR 705
Score = 49.7 bits (117), Expect = 5e-06
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 267 GSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEV-CPGENKQCENTE 325
G ++C+ C++ LG C G+++V C DVDEC T C ++ +C NT
Sbjct: 283 GVHDCQLCSER-LGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC--QHGECANTR 339
Query: 326 GGYRCICAEGY--KQMEGICVKEQIPESA 352
GGY C+C +G+ C+ + + A
Sbjct: 340 GGYTCVCPDGFLLDSSRSSCISQHVISEA 368
Score = 43.1 bits (100), Expect = 5e-04
Identities = 28/90 (31%), Positives = 32/90 (35%), Gaps = 21/90 (23%)
Query: 245 DIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSK-- 302
D+DEC CVNT Y C CS GY +
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCY-------------------CSNGYYYHTQRLE 1256
Query: 303 CLDVDECETEVCPGENKQCENTEGGYRCIC 332
C+D DEC E E +C NT G Y C C
Sbjct: 1257 CIDNDECADEEPACEGGRCVNTVGSYHCTC 1286
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/125 (29%), Positives = 50/125 (40%), Gaps = 20/125 (16%)
Query: 164 GGYGQCE-----GEGTRGGSGHCDCQAGY--------GGEACGQCGLGYFEAERNASHLV 210
G YG+ E G GTR D + + GG G Y E E ++
Sbjct: 1444 GPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGIL 1503
Query: 211 CSACFGPCARCSGPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCG--ADQFCVNTE 266
G C R PE C +C G+ L + CVDI+EC A + C+NT+
Sbjct: 1504 DGCTNGRCVRV--PEGFTC-RCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTD 1560
Query: 267 GSYEC 271
GS+ C
Sbjct: 1561 GSFRC 1565
Score = 40.4 bits (93), Expect = 0.003
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Query: 281 CMGAGPGRCKKCSPGYQ--QVGSKCLDVDECETEVCPGE---NKQCENTEGGYRCICAEG 335
C+ G +C GY+ C+D++EC+ N +C NT+G +RCIC G
Sbjct: 1511 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1570
Query: 336 Y 336
+
Sbjct: 1571 F 1571
Score = 39.7 bits (91), Expect = 0.005
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query: 232 CKKGWALH--HLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
C G+ H L+C+D DEC E C + CVNT GSY C
Sbjct: 1244 CSNGYYYHTQRLECIDNDECADEEPACEGGR-CVNTVGSYHC 1284
Score = 37.7 bits (86), Expect = 0.020
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%)
Query: 210 VCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSY 269
+CS G R S P+ C G+ + C D+DEC T G C + C NT G Y
Sbjct: 289 LCSERLGNSERVSAPDGP----CPTGFERVNGSCEDVDECAT-GGRCQHGE-CANTRGGY 342
Query: 270 EC 271
C
Sbjct: 343 TC 344
Score = 33.5 bits (75), Expect = 0.37
Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 5/35 (14%)
Query: 305 DVDECET---EVCPGENKQCENTEGGYRCICAEGY 336
DVDEC+ +VC ++ C NT GY C C+ GY
Sbjct: 1216 DVDECQLFRDQVC--KSGVCVNTAPGYSCYCSNGY 1248
Score = 33.1 bits (74), Expect = 0.48
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 28/123 (22%)
Query: 134 LCSDSL----KLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGG 189
LCS+ L ++ P G PCP G ER G + T G H +C GG
Sbjct: 289 LCSERLGNSERVSAPDG-------PCPTGFERVNGSCEDVDECATGGRCQHGECANTRGG 341
Query: 190 EACGQCGLGY-FEAERNA--SHLVCSACFGPCAR------CSGPEESN-------CLQCK 233
C C G+ ++ R++ S V S GPC R CS P N C +
Sbjct: 342 YTC-VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG 400
Query: 234 KGW 236
K W
Sbjct: 401 KAW 403
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 99.0 bits (245), Expect = 7e-21
Identities = 80/254 (31%), Positives = 104/254 (40%), Gaps = 59/254 (23%)
Query: 125 QEAPDLFQWLCSD---SLKLCCPAG--TFGPSCLPCPGGTE-----RPCGGYGQCEGEGT 174
QE P C + S CPAG + GP PC E PC YG+CE
Sbjct: 716 QEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGA-PCQDVDECARSPPPCT-YGRCENTE- 772
Query: 175 RGGSGHCDCQAGYGGEACG-QCGLGYFEAERNASHLVCSACFGPCARC-SGPEESNCLQC 232
GS C C G+ G +C + + +HL C P C + P C C
Sbjct: 773 --GSFQCVCPMGFQPNTAGSECE----DVDECENHLAC-----PGQECVNSPGSFQCRTC 821
Query: 233 KKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCK-- 290
G LH +C D+DEC + CG C NTEGS+ C CA G PG C
Sbjct: 822 PSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRC-SCAPGYRAPSGR-PGPCADV 879
Query: 291 ------------------------KCSPGYQ--QVGSKCLDVDEC-ETEVCPGENKQCEN 323
C+PGY+ G+ CLDVDEC E ++C ++ C N
Sbjct: 880 NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLC--QSGICTN 937
Query: 324 TEGGYRCICAEGYK 337
T+G + CIC G++
Sbjct: 938 TDGSFECICPPGHR 951
Score = 88.6 bits (218), Expect = 1e-17
Identities = 76/243 (31%), Positives = 97/243 (39%), Gaps = 66/243 (27%)
Query: 141 LC-CPAG----TFGPSCLPCPGGTERP--CGGYGQCEGEGTRGGSGHCDCQAGYGGEACG 193
LC CPAG G SC T+ P CG G C+ GS C C AG+ G AC
Sbjct: 653 LCVCPAGYQAAPHGASCQDVDECTQSPGLCGR-GACKN---LPGSFRCVCPAGFRGSACE 708
Query: 194 Q-----------CGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLK 242
+ CG G + + H C A F R GP
Sbjct: 709 EDVDECAQEPPPCGPGRCDNTAGSFHCACPAGF----RSRGPGAP--------------- 749
Query: 243 CVDIDECGTEGANCGADQFCVNTEGSYEC------------------RDCAK--ACLG-- 280
C D+DEC C + C NTEGS++C +C AC G
Sbjct: 750 CQDVDECARSPPPCTYGR-CENTEGSFQCVCPMGFQPNTAGSECEDVDECENHLACPGQE 808
Query: 281 CMGA-GPGRCKKCSPGYQQVGSKCLDVDECETEVCP-GENKQCENTEGGYRCICAEGYKQ 338
C+ + G +C+ C G+ +C DVDEC + P G + C NTEG +RC CA GY+
Sbjct: 809 CVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRA 868
Query: 339 MEG 341
G
Sbjct: 869 PSG 871
Score = 86.3 bits (212), Expect = 5e-17
Identities = 74/249 (29%), Positives = 89/249 (35%), Gaps = 51/249 (20%)
Query: 135 CSDSLKLCCP-------AGTFGPSCLP---CPGGTERPCGGYGQC-EGEGTRGGSGHCDC 183
CS C P G+F SC P P G PC +C EG+ H +C
Sbjct: 838 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFC---FPHGEC 894
Query: 184 QAGYGGEACGQCGLGYFEAERNASHLVCSACF-------GPCARCSGPEESNCLQCKKGW 236
G AC C GY R AS L C G C G E C +
Sbjct: 895 LNTDGSFAC-TCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAG 953
Query: 237 ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC-RDCAKACLG-----------CMGA 284
C+D+DEC G Q C N+ GSY C RDC C
Sbjct: 954 P-DLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY 1012
Query: 285 GPGRC---------------KKCSPGYQQV-GSKCLDVDECETEVCPGENKQCENTEGGY 328
GP C C PGYQ G C DVDEC G + C+N G +
Sbjct: 1013 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSF 1072
Query: 329 RCICAEGYK 337
+C+C +GY+
Sbjct: 1073 QCLCDQGYE 1081
Score = 63.9 bits (154), Expect = 3e-10
Identities = 61/223 (27%), Positives = 80/223 (35%), Gaps = 47/223 (21%)
Query: 134 LCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRG-GSGHCD---------- 182
+C + ++C P C+ P G C + +GTR C
Sbjct: 548 MCQRNPQVCGPG-----RCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR 602
Query: 183 CQAGYGGEACGQCGLGYFEAERNASHLVCSACFG---PC--ARCSGPEESNCLQCKKGW- 236
C+ G C CG G+ R A L C PC RC S C G+
Sbjct: 603 CENSPGSFRC-VCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQ 661
Query: 237 -ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPG 295
A H C D+DEC CG C N GS+ C C G
Sbjct: 662 AAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFRC-------------------VCPAG 701
Query: 296 YQQVGSKCL-DVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
++ GS C DVDEC E P +C+NT G + C C G++
Sbjct: 702 FR--GSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFR 742
Score = 49.7 bits (117), Expect = 5e-06
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 267 GSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEV-CPGENKQCENTE 325
G ++C+ C++ LG C G+++V C DVDEC T C ++ +C NT
Sbjct: 320 GVHDCQLCSER-LGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRC--QHGECANTR 376
Query: 326 GGYRCICAEGY--KQMEGICVKEQIPESA 352
GGY C+C +G+ C+ + + A
Sbjct: 377 GGYTCVCPDGFLLDSSRSSCISQHVISEA 405
Score = 43.1 bits (100), Expect = 5e-04
Identities = 28/90 (31%), Positives = 32/90 (35%), Gaps = 21/90 (23%)
Query: 245 DIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSK-- 302
D+DEC CVNT Y C CS GY +
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCY-------------------CSNGYYYHTQRLE 1293
Query: 303 CLDVDECETEVCPGENKQCENTEGGYRCIC 332
C+D DEC E E +C NT G Y C C
Sbjct: 1294 CIDNDECADEEPACEGGRCVNTVGSYHCTC 1323
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/125 (29%), Positives = 50/125 (40%), Gaps = 20/125 (16%)
Query: 164 GGYGQCE-----GEGTRGGSGHCDCQAGY--------GGEACGQCGLGYFEAERNASHLV 210
G YG+ E G GTR D + + GG G Y E E ++
Sbjct: 1481 GPYGESEAPAPPGPGTRWPYRSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGIL 1540
Query: 211 CSACFGPCARCSGPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCG--ADQFCVNTE 266
G C R PE C +C G+ L + CVDI+EC A + C+NT+
Sbjct: 1541 DGCTNGRCVRV--PEGFTC-RCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTD 1597
Query: 267 GSYEC 271
GS+ C
Sbjct: 1598 GSFRC 1602
Score = 40.4 bits (93), Expect = 0.003
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Query: 281 CMGAGPGRCKKCSPGYQ--QVGSKCLDVDECETEVCPGE---NKQCENTEGGYRCICAEG 335
C+ G +C GY+ C+D++EC+ N +C NT+G +RCIC G
Sbjct: 1548 CVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPG 1607
Query: 336 Y 336
+
Sbjct: 1608 F 1608
Score = 39.7 bits (91), Expect = 0.005
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query: 232 CKKGWALH--HLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
C G+ H L+C+D DEC E C + CVNT GSY C
Sbjct: 1281 CSNGYYYHTQRLECIDNDECADEEPACEGGR-CVNTVGSYHC 1321
Score = 37.7 bits (86), Expect = 0.020
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 6/62 (9%)
Query: 210 VCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSY 269
+CS G R S P+ C G+ + C D+DEC T G C + C NT G Y
Sbjct: 326 LCSERLGNSERVSAPDGP----CPTGFERVNGSCEDVDECAT-GGRCQHGE-CANTRGGY 379
Query: 270 EC 271
C
Sbjct: 380 TC 381
Score = 33.5 bits (75), Expect = 0.37
Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 5/35 (14%)
Query: 305 DVDECET---EVCPGENKQCENTEGGYRCICAEGY 336
DVDEC+ +VC ++ C NT GY C C+ GY
Sbjct: 1253 DVDECQLFRDQVC--KSGVCVNTAPGYSCYCSNGY 1285
Score = 33.1 bits (74), Expect = 0.48
Identities = 37/123 (30%), Positives = 48/123 (39%), Gaps = 28/123 (22%)
Query: 134 LCSDSL----KLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGG 189
LCS+ L ++ P G PCP G ER G + T G H +C GG
Sbjct: 326 LCSERLGNSERVSAPDG-------PCPTGFERVNGSCEDVDECATGGRCQHGECANTRGG 378
Query: 190 EACGQCGLGY-FEAERNA--SHLVCSACFGPCAR------CSGPEESN-------CLQCK 233
C C G+ ++ R++ S V S GPC R CS P N C +
Sbjct: 379 YTC-VCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVG 437
Query: 234 KGW 236
K W
Sbjct: 438 KAW 440
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 93.6 bits (231), Expect = 3e-19
Identities = 59/178 (33%), Positives = 76/178 (42%), Gaps = 42/178 (23%)
Query: 166 YGQCEGEGTRGGSGHCDCQAGY----GGEAC---GQCGLGYFEAERNASHLVCSACFGPC 218
+G+CE GS C CQ GY G C +C +G + +AS L F
Sbjct: 1338 FGECENTK---GSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSF--- 1391
Query: 219 ARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKAC 278
+CS C++GW + +KC+D+DEC C + CVNT GSY C
Sbjct: 1392 -KCS---------CREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRC------- 1434
Query: 279 LGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGY 336
CS G+ G C DVDEC + EN QC N G YRC C G+
Sbjct: 1435 ------------ACSEGFTGDGFTCSDVDECAENINLCENGQCLNVPGAYRCECEMGF 1480
Score = 75.1 bits (183), Expect = 1e-13
Identities = 50/169 (29%), Positives = 69/169 (40%), Gaps = 41/169 (24%)
Query: 177 GSGHCDCQAGY----GGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQC 232
GS C C GY G+ C L + +++ +C G +C
Sbjct: 2511 GSYQCSCPRGYVLQEDGKTCKD--LDECQTKQHNCQFLCVNTLGGFT----------CKC 2558
Query: 233 KKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKC 292
G+ HH C+D +ECG++ + CGA C NT GS+ C +C
Sbjct: 2559 PPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSC-------------------EC 2599
Query: 293 SPGY--QQVGSKCLDVDECE-TEVCPGENKQCENTEGGYRCICAEGYKQ 338
G+ G C DVDEC+ C C+N GGYRC C +GY Q
Sbjct: 2600 QRGFSLDATGLNCEDVDECDGNHRC---QHGCQNILGGYRCGCPQGYIQ 2645
Score = 74.3 bits (181), Expect = 2e-13
Identities = 60/207 (28%), Positives = 83/207 (40%), Gaps = 50/207 (24%)
Query: 166 YGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHL--------VCSACFGP 217
YG+C GS C C +G+ + ERN + + +C + G
Sbjct: 1086 YGKCRNTI---GSFKCRCNSGFALDM----------EERNCTDIDECRISPDLCGS--GI 1130
Query: 218 CARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC------ 271
C G E C + + + C+DIDEC C CVNTEGS++C
Sbjct: 1131 CVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGT-CVNTEGSFQCDCPLGH 1189
Query: 272 ------RDCA---KACLGCMGAGPGRCKK--------CSPGYQQVGSK--CLDVDECETE 312
DC + L G+C C+PGYQ + C D+DEC
Sbjct: 1190 ELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMI- 1248
Query: 313 VCPGENKQCENTEGGYRCICAEGYKQM 339
+ G + QC N+EG Y C C+EGY M
Sbjct: 1249 MNGGCDTQCTNSEGSYECSCSEGYALM 1275
Score = 73.6 bits (179), Expect = 3e-13
Identities = 73/226 (32%), Positives = 94/226 (41%), Gaps = 48/226 (21%)
Query: 132 QWLCSDSLK--LC-CPAGTFGPSCLPCPGGTE---RP--CGGYGQCEGEGTRGGSGHCDC 183
Q+LC ++L C CP G F C E +P CG G C+ GS C+C
Sbjct: 2544 QFLCVNTLGGFTCKCPPG-FTQHHTACIDNNECGSQPSLCGAKGICQNTP---GSFSCEC 2599
Query: 184 QAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHL-- 241
Q G+ +A G E + N C C G C Q G+ H+
Sbjct: 2600 QRGFSLDATGLNCEDVDECDGN------HRCQHGCQNILGGYRCGCPQ---GYIQHYQWN 2650
Query: 242 KCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQ--QV 299
+CVD +EC A CG+ C NT GSY+C C G+ Q
Sbjct: 2651 QCVDENECSNPNA-CGSAS-CYNTLGSYKCA-------------------CPSGFSFDQF 2689
Query: 300 GSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQM-EGICV 344
S C DV+EC + P N C NTEGGY C C GY ++ +G CV
Sbjct: 2690 SSACHDVNECSSSKNPC-NYGCSNTEGGYLCGCPPGYYRVGQGHCV 2734
Score = 70.9 bits (172), Expect = 2e-12
Identities = 97/374 (25%), Positives = 122/374 (32%), Gaps = 120/374 (32%)
Query: 30 QPSPPPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETR 89
QP PPP P PQP P V S G E GG A E S R
Sbjct: 29 QPQPPPPKPPRPQPPPQQ-----VRSATAGSE--------GGFLAPEYREEGAAVASRVR 75
Query: 90 L---VEVLEG--VCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCP 144
+VL G VC S F + W + P Q + C
Sbjct: 76 RRGQQDVLRGPNVCG-SRFHSY--------CCPGW-----KTLPGGNQCIVPICRNSCGD 121
Query: 145 AGTFGPSCLPCPGGT-ERPCGGYG--QCEGEGTRGGS---GHCDCQAGYGGEACGQ---- 194
P+ C G CG QC GG+ HC CQ GY G CGQ
Sbjct: 122 GFCSRPNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADDHCQCQKGYIGTYCGQPVCE 181
Query: 195 ----------------CGLGYF--EAERN-----------------------ASHLVCSA 213
C G+ + ER+ + +C A
Sbjct: 182 NGCQNGGRCIGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCA 241
Query: 214 CFG-----PCARCSGPEESNCLQCKKGWA--LHHLKCVDIDECGTEGANCGADQFCVNTE 266
G PC C + C++G+ + C D+DEC C C+NT
Sbjct: 242 TIGRAWGHPCEMCPAQPQP----CRRGFIPNIRTGACQDVDECQAIPGICQGGN-CINTV 296
Query: 267 GSYECRDCAKACLGCMGAGPGRCKKCSPGYQQ--VGSKCLDVDECETEVCPG--ENKQCE 322
GS+ECR C G++Q KC D+DEC + PG E +C
Sbjct: 297 GSFECR-------------------CPAGHKQSETTQKCEDIDECS--IIPGICETGECS 335
Query: 323 NTEGGYRCICAEGY 336
NT G Y C+C GY
Sbjct: 336 NTVGSYFCVCPRGY 349
Score = 70.5 bits (171), Expect = 3e-12
Identities = 63/223 (28%), Positives = 86/223 (38%), Gaps = 44/223 (19%)
Query: 131 FQWLCSDSLKL--------CCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCD 182
++ LC D L + P GT G P G GG G G G S
Sbjct: 413 YRRLCMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFS---- 468
Query: 183 CQAGYGGEACGQCGLGYFEAER---NASHLVCSACFGPC--ARCSGPEESNCLQCKKGWA 237
G GG G G G N + +C C RC S +C G+
Sbjct: 469 --PGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYK 526
Query: 238 LH-HLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGY 296
+ C+D+DEC + G CVNT GSY C KC G+
Sbjct: 527 QDANGDCIDVDECTSNPCTNGD---CVNTPGSYYC-------------------KCHAGF 564
Query: 297 QQVGSK--CLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
Q+ +K C+D+DEC +N +C NT+G ++CIC G++
Sbjct: 565 QRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFE 607
Score = 70.5 bits (171), Expect = 3e-12
Identities = 55/202 (27%), Positives = 76/202 (37%), Gaps = 43/202 (21%)
Query: 142 CCPAGT-FGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYF 200
CC G +G C CP +P GT+ C AG+ G ++
Sbjct: 1026 CCAVGAAWGTECEECP----KP----------GTKEYETLCPRGAGFANRGDVLTGRPFY 1071
Query: 201 EAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWAL--HHLKCVDIDECGTEGANCGA 258
+ +G C G S +C G+AL C DIDEC CG+
Sbjct: 1072 KDINECKAFPGMCTYGKCRNTIG---SFKCRCNSGFALDMEERNCTDIDECRISPDLCGS 1128
Query: 259 DQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQ---VGSKCLDVDECETEVCP 315
CVNT GS+EC +C GY+ + C+D+DECE
Sbjct: 1129 G-ICVNTPGSFEC-------------------ECFEGYESGFMMMKNCMDIDECERNPLL 1168
Query: 316 GENKQCENTEGGYRCICAEGYK 337
C NTEG ++C C G++
Sbjct: 1169 CRGGTCVNTEGSFQCDCPLGHE 1190
Score = 69.7 bits (169), Expect = 5e-12
Identities = 55/170 (32%), Positives = 69/170 (40%), Gaps = 44/170 (25%)
Query: 177 GSGHCDCQAGY----GGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQC 232
GS CDC G+ E C E + S +C G C G + +C
Sbjct: 1179 GSFQCDCPLGHELSPSREDCVDIN------ECSLSDNLCRN--GKCVNMIGTYQCSC--- 1227
Query: 233 KKGWAL--HHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCK 290
G+ C DIDEC N G D C N+EGSYEC
Sbjct: 1228 NPGYQATPDRQGCTDIDECMI--MNGGCDTQCTNSEGSYEC------------------- 1266
Query: 291 KCSPGYQQV--GSKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGY 336
CS GY + G C D+DECE ++C G QC N G YRC+C +G+
Sbjct: 1267 SCSEGYALMPDGRSCADIDECENNPDICDG--GQCTNIPGEYRCLCYDGF 1314
Score = 67.8 bits (164), Expect = 2e-11
Identities = 57/194 (29%), Positives = 75/194 (38%), Gaps = 36/194 (18%)
Query: 177 GSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSAC-FGPCARCSGPEESNCLQCKKG 235
GS C+C AG+ G C +RN + + C G C G + C K
Sbjct: 1872 GSYRCECAAGFKLSPNGAC------VDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKA 1925
Query: 236 WALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC-----------RDCAKA--CLGCM 282
+ C+D+DEC E CG + C NT GSY C DC C
Sbjct: 1926 -SQDQTMCMDVDEC--ERHPCG-NGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFF 1981
Query: 283 G--AGPGRCKK--------CSPGYQQV--GSKCLDVDECETEVCPGENKQCENTEGGYRC 330
G GRC C+ GY+ G C+D +EC C+N EG +RC
Sbjct: 1982 GQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRC 2041
Query: 331 ICAEGYKQMEGICV 344
IC GY+ C+
Sbjct: 2042 ICPPGYEVKSENCI 2055
Score = 67.4 bits (163), Expect = 2e-11
Identities = 56/199 (28%), Positives = 78/199 (39%), Gaps = 55/199 (27%)
Query: 178 SGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCAR--CSGPEESNCLQCKKG 235
S C+C GY +A G C + + S+ PC C S +C G
Sbjct: 516 SYRCECNMGYKQDANGDC----IDVDECTSN--------PCTNGDCVNTPGSYYCKCHAG 563
Query: 236 WALHHLK--CVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCS 293
+ K C+DIDEC G C + CVNT+GS++C C+
Sbjct: 564 FQRTPTKQACIDIDECIQNGVLCKNGR-CVNTDGSFQCI-------------------CN 603
Query: 294 PGYQQV--GSKCLDVDECET-EVCPGENKQCENTEGGYRCICAEGYK------------- 337
G++ G C+D DEC T +C N C N +G ++CIC G+
Sbjct: 604 AGFELTTDGKNCVDHDECTTTNMCL--NGMCINEDGSFKCICKPGFVLAPNGRYCTDVDE 661
Query: 338 -QMEGICVKEQIPESAGFF 355
Q GIC+ S G F
Sbjct: 662 CQTPGICMNGHCINSEGSF 680
Score = 67.0 bits (162), Expect = 3e-11
Identities = 63/222 (28%), Positives = 83/222 (37%), Gaps = 62/222 (27%)
Query: 152 CLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACG-------QCGLGYFEAER 204
CL PG GQC GS C+C GY + G +C +G
Sbjct: 2175 CLESPGICSN-----GQCINTD---GSFRCECPMGYNLDYTGVRCVDTDECSIG------ 2220
Query: 205 NASHLVCSACF-GPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCV 263
+ C G C G E NC + + + + C DI+EC C C+
Sbjct: 2221 -------NPCGNGTCTNVIGSFECNCNEGFEPGPM--MNCEDINECAQNPLLCAFR--CM 2269
Query: 264 NTEGSYECR------------------DCAKACLGCMGAGPGRCKK--------CSPGYQ 297
NT GSYEC +CA+ C G CK C PG
Sbjct: 2270 NTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGM-MCKNLIGTFMCICPPGMA 2328
Query: 298 QV--GSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
+ G C+D +EC T+ EN +C N G YRC C EG++
Sbjct: 2329 RRPDGEGCVDENECRTKPGICENGRCVNIIGSYRCECNEGFQ 2370
Score = 66.2 bits (160), Expect = 5e-11
Identities = 53/177 (29%), Positives = 70/177 (39%), Gaps = 33/177 (18%)
Query: 211 CSACFGPCAR--CSGPEESNCLQCKKGWALHHLK--CVDIDECGTEGANCGADQFCVNTE 266
C G CA C S +C G++ + L C DIDEC C + C+N+
Sbjct: 1812 CKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSP 1871
Query: 267 GSYECRDCAKACLGCMGA--------------GPGRCKKCSPGYQ----------QVGSK 302
GSY C A L GA G C YQ Q +
Sbjct: 1872 GSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTM 1931
Query: 303 CLDVDECETEVCPGENKQCENTEGGYRCICAEGYK-QMEGICVKEQIPESAGFFSEM 358
C+DVDECE C N C+NT G Y C+C G++ C+ I E + FF ++
Sbjct: 1932 CMDVDECERHPC--GNGTCKNTVGSYNCLCYPGFELTHNNDCL--DIDECSSFFGQV 1984
Score = 64.7 bits (156), Expect = 2e-10
Identities = 53/185 (28%), Positives = 68/185 (36%), Gaps = 45/185 (24%)
Query: 181 CDCQAGYG-GEACGQC--------------GLGYFEAERNASHLVCSACFGPCARCSGPE 225
C C G G G C C G GY R+ +C
Sbjct: 2410 CCCDGGRGWGHQCELCPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTM 2469
Query: 226 ESNCLQCKKGWA--LHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMG 283
S CK G+ + C+D+DEC C + C NTEGSY+C
Sbjct: 2470 GSFRCFCKVGYTTDISGTSCIDLDECSQSPKPC--NYICKNTEGSYQC------------ 2515
Query: 284 AGPGRCKKCSPGY--QQVGSKCLDVDECETEVCPGENKQ--CENTEGGYRCICAEGYKQM 339
C GY Q+ G C D+DEC+T+ N Q C NT GG+ C C G+ Q
Sbjct: 2516 -------SCPRGYVLQEDGKTCKDLDECQTK---QHNCQFLCVNTLGGFTCKCPPGFTQH 2565
Query: 340 EGICV 344
C+
Sbjct: 2566 HTACI 2570
Score = 58.5 bits (140), Expect = 1e-08
Identities = 59/228 (25%), Positives = 77/228 (33%), Gaps = 60/228 (26%)
Query: 146 GTFGPSCLP----CPGGTERPCGGYGQCEGEG--------TRGGSGHCDCQAG------- 186
G+F C P P G R C +C+ G GS CDC G
Sbjct: 637 GSFKCICKPGFVLAPNG--RYCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDG 694
Query: 187 ------------YGGEACGQCGLGYFEAERNASHLVCSACFG---PCARCSGPEESNCLQ 231
YGG G C + A + + +G PC C +
Sbjct: 695 RVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHG 754
Query: 232 -CKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCK 290
C G + + DI+EC + C A+ C N GSY C
Sbjct: 755 LCSSGVGIT-VDGRDINECALDPDIC-ANGICENLRGSYRCN------------------ 794
Query: 291 KCSPGYQQ--VGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGY 336
C+ GY+ G C+D+DEC +N C NT G Y C C GY
Sbjct: 795 -CNSGYEPDASGRNCIDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGY 841
Score = 57.8 bits (138), Expect = 2e-08
Identities = 47/168 (27%), Positives = 62/168 (36%), Gaps = 30/168 (17%)
Query: 177 GSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPC-ARCSGPEESNCLQCKKG 235
G+ C C GY Q G + + C G C +C+ E S C +G
Sbjct: 1221 GTYQCSCNPGYQATPDRQ---GCTDIDE------CMIMNGGCDTQCTNSEGSYECSCSEG 1271
Query: 236 WAL--HHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCS 293
+AL C DIDEC C Q C N G Y C C + M
Sbjct: 1272 YALMPDGRSCADIDECENNPDICDGGQ-CTNIPGEYRCL-CYDGFMASMDM--------- 1320
Query: 294 PGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEG 341
C+DV+EC+ +CENT+G + C C GY +G
Sbjct: 1321 -------KTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKG 1361
Score = 55.1 bits (131), Expect = 1e-07
Identities = 49/179 (27%), Positives = 65/179 (36%), Gaps = 44/179 (24%)
Query: 183 CQAGYGGEACGQCGLGYFEAERNASHLVCSACFG-------PCARCSGPEESNCLQCKKG 235
C Y G C E N + +C + PC C P ++
Sbjct: 1740 CYRSYNGTTCEN------ELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGN 1793
Query: 236 -----WALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCK 290
+ +H K VDIDEC C A+ C+N GS+ C
Sbjct: 1794 IPGFTFDIHTGKAVDIDECKEIPGIC-ANGVCINQIGSFRC------------------- 1833
Query: 291 KCSPG--YQQVGSKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGYK-QMEGICV 344
+C G Y + C D+DEC +C N C N+ G YRC CA G+K G CV
Sbjct: 1834 ECPTGFSYNDLLLVCEDIDECSNGDNLCQ-RNADCINSPGSYRCECAAGFKLSPNGACV 1891
Score = 52.4 bits (124), Expect = 8e-07
Identities = 82/325 (25%), Positives = 112/325 (34%), Gaps = 100/325 (30%)
Query: 142 CC--PAGTFGPSCLPCPGGTERPCGGY--------------------------GQCEGEG 173
CC P FG C PCP G G CE
Sbjct: 729 CCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANGICEN-- 786
Query: 174 TRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCK 233
GS C+C +GY +A G+ + E N L+C G C G S C
Sbjct: 787 -LRGSYRCNCNSGYEPDASGRNCIDIDECLVN--RLLCDN--GLCRNTPG---SYSCTCP 838
Query: 234 KGWALHHLK--CVDIDECGTEGANCGADQFCVNTEGSYECR---------------DCAK 276
G+ C DI+EC + GA C N GS+ C D K
Sbjct: 839 PGYVFRTETETCEDINECESNPCVNGA---CRNNLGSFNCECSPGSKLSSTGLICIDSLK 895
Query: 277 A-----------------------CLGCMGAGPG----RCK---KCSPGYQQV-GSKCLD 305
C +GA G RC+ C G ++ G C D
Sbjct: 896 GTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCED 955
Query: 306 VDECET--EVCPGENKQCENTEGGYRCICAEGYKQMEG---ICVKEQIPESAGFFSEMTE 360
V+ECE VCP N +C N++G + C C EG ++G +C+ ++ + + + E
Sbjct: 956 VNECEVFPGVCP--NGRCVNSKGSFHCECPEGL-TLDGTGRVCLDIRMEQC---YLKWDE 1009
Query: 361 DELVVLQQMFFGIIICALATLAAKG 385
DE + F + C A AA G
Sbjct: 1010 DECIHPVPGKFRMDACCCAVGAAWG 1034
Score = 50.4 bits (119), Expect = 3e-06
Identities = 75/317 (23%), Positives = 100/317 (31%), Gaps = 115/317 (36%)
Query: 138 SLKLCCPAGTFGPS--CLP---CPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEA- 191
S K C G G C+ C GT + C QC GS C C G+ G+
Sbjct: 1390 SFKCSCREGWIGNGIKCIDLDECSNGTHQ-CSINAQCVNTP---GSYRCACSEGFTGDGF 1445
Query: 192 -------CGQ--------------------CGLGYFEAERNASHLVCSAC-------FGP 217
C + C +G+ A + S C FG
Sbjct: 1446 TCSDVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQDIDECSFQNICVFGT 1505
Query: 218 CARCSGPEESNCLQCKKGWALHHL--KCVDIDECGTEGANCGADQFCVNTEGSYECR--- 272
C G +C+ C G+ L C DIDEC + NC + CVNT G YEC
Sbjct: 1506 CNNLPGM--FHCI-CDDGYELDRTGGNCTDIDECA-DPINC-VNGLCVNTPGRYECNCPP 1560
Query: 273 ---------------------------DCAKACLGCMGAGPGRCKKCSPGYQQVGSKCL- 304
D + +C +G G R C + G+ C
Sbjct: 1561 DFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCSLGKAWGNPCET 1620
Query: 305 -----------------------------DVDECET--EVCPGENKQCENTEGGYRCICA 333
D+DEC+ +C G N C NT G ++C C
Sbjct: 1621 CPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGN--CINTFGSFQCECP 1678
Query: 334 EGYKQMEGICVKEQIPE 350
+GY E + E I E
Sbjct: 1679 QGYYLSEDTRICEDIDE 1695
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/225 (26%), Positives = 78/225 (34%), Gaps = 44/225 (19%)
Query: 135 CSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTR---GGSGHCDCQAGYGGEA 191
C+D + P C+ PG E C Q G G+C + G G+
Sbjct: 1530 CTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDG 1589
Query: 192 CGQCGLGYFEAERNASHLVCSACFG-----PCARC---SGPEESNCLQCKKGWALHHLKC 243
C E S C G PC C + E +G+ + +
Sbjct: 1590 SLSCNT---EIGVGVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITI 1646
Query: 244 V--DIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGY--QQV 299
+ DIDEC C C+NT GS++C +C GY +
Sbjct: 1647 ILEDIDECQELPGLCQGGN-CINTFGSFQC-------------------ECPQGYYLSED 1686
Query: 300 GSKCLDVDECETE--VC-PGENKQCENTEGGYRCICAEGYKQMEG 341
C D+DEC VC PG C NT G Y CIC Y Q+ G
Sbjct: 1687 TRICEDIDECFAHPGVCGPGT---CYNTLGNYTCICPPEYMQVNG 1728
Score = 49.7 bits (117), Expect = 5e-06
Identities = 44/148 (29%), Positives = 63/148 (42%), Gaps = 29/148 (19%)
Query: 211 CSACFGPCA--RCSGPEESNCLQCKKGWALHH--LKCVDIDECGTEGANCGADQFCVNTE 266
C G C+ +C + S +C G+ L + ++CVD DEC G CG + C N
Sbjct: 2175 CLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSI-GNPCG-NGTCTNVI 2232
Query: 267 GSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETE--VCPGENKQCENT 324
GS+EC +C + G PG C D++EC +C +C NT
Sbjct: 2233 GSFEC-NCNE------GFEPGPMMNCE-----------DINECAQNPLLCAF---RCMNT 2271
Query: 325 EGGYRCICAEGYKQMEGICVKEQIPESA 352
G Y C C GY E + + + E A
Sbjct: 2272 FGSYECTCPIGYALREDQKMCKDLDECA 2299
Score = 47.0 bits (110), Expect = 3e-05
Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 5/71 (7%)
Query: 271 CRDCAKACLG--CMGAGPGRCKKCSPGYQQ-VGSKCLDVDECETEVCPGENKQCENTEGG 327
C+ A CL C+ +C+ GY+Q C+DVDEC + C N C NT G
Sbjct: 498 CKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCT--NGDCVNTPGS 555
Query: 328 YRCICAEGYKQ 338
Y C C G+++
Sbjct: 556 YYCKCHAGFQR 566
Score = 45.1 bits (105), Expect = 1e-04
Identities = 70/297 (23%), Positives = 96/297 (32%), Gaps = 100/297 (33%)
Query: 131 FQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYG-- 188
+Q +C + K A C+ PCG G C+ GS +C C G+
Sbjct: 1915 YQCICHNGFK----ASQDQTMCMDVDECERHPCGN-GTCKNTV---GSYNCLCYPGFELT 1966
Query: 189 ---------------GEAC--GQC--GLGYFEAERNASHLV------------CSACFGP 217
G+ C G+C +G F+ N + + C A G
Sbjct: 1967 HNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALPGS 2026
Query: 218 CA--RCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC---- 271
C+ C E S C G+ + C+DI+EC E N C NT G ++C
Sbjct: 2027 CSPGTCQNLEGSFRCICPPGYEVKSENCIDINECD-EDPNICLFGSCTNTPGGFQCLCPP 2085
Query: 272 --------RDC---------------------------AKACLGCM-GAGPGRCKKCSPG 295
R C AK C M G G G + P
Sbjct: 2086 GFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPK 2145
Query: 296 YQQVGSKCL----------------DVDECETEVCPGENKQCENTEGGYRCICAEGY 336
+V + L DV+EC N QC NT+G +RC C GY
Sbjct: 2146 DDEVAFQDLCPYGHGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGY 2202
Score = 42.7 bits (99), Expect = 6e-04
Identities = 56/221 (25%), Positives = 70/221 (31%), Gaps = 74/221 (33%)
Query: 177 GSGHCDCQAGYG----GEAC---GQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNC 229
GS C C GY + C +C G + E ++C G C
Sbjct: 2273 GSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRG--MMCKNLIGTFM---------C 2321
Query: 230 LQCKKGWALHH--LKCVDIDECGTEGANCGADQFCVNTEGSYECR--------DCAKACL 279
+ C G A CVD +EC T+ C + CVN GSY C CL
Sbjct: 2322 I-CPPGMARRPDGEGCVDENECRTKPGICENGR-CVNIIGSYRCECNEGFQSSSSGTECL 2379
Query: 280 G------------------------------CMGAGPG---RCKKCS-PGYQQVGSKC-- 303
C G G +C+ C PG Q C
Sbjct: 2380 DNRQGLCFAEVLQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPH 2439
Query: 304 --------LDVDECETEVCPGENKQCENTEGGYRCICAEGY 336
D+DEC+ N QC NT G +RC C GY
Sbjct: 2440 GPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGY 2480
>gi|61743980 stabilin 2 precursor [Homo sapiens]
Length = 2551
Score = 87.8 bits (216), Expect = 2e-17
Identities = 69/220 (31%), Positives = 88/220 (40%), Gaps = 31/220 (14%)
Query: 142 CCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFE 201
CCP G +GP C+ CPGG PC G G C EG G+G C CQ G+GG AC C
Sbjct: 100 CCP-GRWGPDCIECPGGAGSPCNGRGSC-AEGME-GNGTCSCQEGFGGTACETCADDNLF 156
Query: 202 AERNASHLVCSACFGPCARCSGPEESNCLQCKKGWA----------LHHLKCVDIDEC-- 249
+S VC+ G C SG + +C + L C + C
Sbjct: 157 GPSCSS--VCNCVHGVCN--SGLDGDGTCECYSAYTGPKCDKPIPECAALLCPENSRCSP 212
Query: 250 GTEGANCGADQFCVNTEGSYECRDCAKACL--------GCMGAGPGRCK-KCSPGYQQVG 300
TE N + N G + D CL C GP R C GY+ G
Sbjct: 213 STEDENKLECKCLPNYRGDGKYCDPINPCLRKICHPHAHCTYLGPNRHSCTCQEGYRGDG 272
Query: 301 SKCLDVDECETEV--CPGENKQCE-NTEGGYRCICAEGYK 337
CL VD C+ CP ++ C+ + G C C E Y+
Sbjct: 273 QVCLPVDPCQINFGNCPTKSTVCKYDGPGQSHCECKEHYQ 312
Score = 82.8 bits (203), Expect = 5e-16
Identities = 64/210 (30%), Positives = 87/210 (41%), Gaps = 39/210 (18%)
Query: 143 CPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEA 202
C AG FGP C PCPG + C G G C +G G+G C+C G+ G AC C G +
Sbjct: 1336 CCAGFFGPQCQPCPGNAQNVCFGNGICL-DGV-NGTGVCECGEGFSGTACETCTEGKYGI 1393
Query: 203 ERNASHLVCSACFGPCARCSGPEESNCLQCKKGW-ALHHLKCVDIDEC-GT--EGANCGA 258
+ + CS G C + GP C GW +H D C GT ANC
Sbjct: 1394 HCDQA---CSCVHGRCNQ--GPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANC-- 1446
Query: 259 DQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETE--VCPG 316
N++G+ C KC+ G+Q G+ C ++ CE C
Sbjct: 1447 ---LTNSDGTASC-------------------KCAAGFQGNGTICTAINACEISNGGCSA 1484
Query: 317 ENKQCENTEGGYR-CICAEGYKQMEGICVK 345
+ C+ T G R C C GY +C++
Sbjct: 1485 K-ADCKRTTPGRRVCTCKAGYTGDGIVCLE 1513
Score = 80.9 bits (198), Expect = 2e-15
Identities = 72/279 (25%), Positives = 106/279 (37%), Gaps = 74/279 (26%)
Query: 135 CSDSLKL--CCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEAC 192
C+ ++K+ CC G +GP C CPGG PC G GQC + GG+G C C+ G+ G C
Sbjct: 719 CNATVKIPKCCK-GFYGPDCNQCPGGFSNPCSGNGQC--ADSLGGNGTCICEEGFQGSQC 775
Query: 193 GQCGLGYFEAERNASHLVC------------SACF-GPC--------------------- 218
C R +C AC G C
Sbjct: 776 QFCSDPNKYGPRCNKKCLCVHGTCNNRIDSDGACLTGTCRDGSAGRLCDKQTSACGPYVQ 835
Query: 219 -----ARCSGPEESNCLQCKKGWALHHLKCVDIDEC-GTEGANCGADQFCVNT-EGSYEC 271
A C + CK G+ C ++D C G C + C+ T G++ C
Sbjct: 836 FCHIHATCEYSNGTASCICKAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTC 895
Query: 272 ----------RDCAKA--CL-----------GCMGAGPGRCK-KCSPGYQQVGSKCLDVD 307
RDC++ CL C+ GPG+ + +C G++ G C +
Sbjct: 896 VCQQGWTGNGRDCSEINNCLLPSAGGCHDNASCLYVGPGQNECECKKGFRGNGIDCEPIT 955
Query: 308 EC--ETEVCPGENKQCENTEGG-YRCICAEGYKQMEGIC 343
C +T C C++T G + C+C EGY+ +C
Sbjct: 956 SCLEQTGKC-HPLASCQSTSSGVWSCVCQEGYEGDGFLC 993
Score = 77.4 bits (189), Expect = 2e-14
Identities = 64/238 (26%), Positives = 82/238 (34%), Gaps = 48/238 (20%)
Query: 143 CPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEA 202
C G FG C CPGG + PC G C + +G C C G+ G AC C G F
Sbjct: 1950 CCKGYFGRDCQACPGGPDAPCNNRGVCLDQ--YSATGECKCNTGFNGTACEMCWPGRFGP 2007
Query: 203 ERNASHLVCSAC----FGPCARCSGPEESNCLQCKKGW------------------ALHH 240
+ C C G C G S C+ GW H
Sbjct: 2008 D-------CLPCGCSDHGQCD--DGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAH 2058
Query: 241 LKCVDIDECGT------EGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSP 294
C + + C +G C FC G CAK C G C
Sbjct: 2059 ATCKENNTCECNLDYEGDGITCTVVDFCKQDNGG-----CAKVA-RCSQKGTKVSCSCQK 2112
Query: 295 GYQQVGSKCLDVDECETEVCPG--ENKQCENT-EGGYRCICAEGYKQMEGICVKEQIP 349
GY+ G C ++D C + G E+ C+ T G ++C C Y C EQ+P
Sbjct: 2113 GYKGDGHSCTEIDPCADGLNGGCHEHATCKMTGPGKHKCECKSHYVGDGLNCEPEQLP 2170
Score = 38.5 bits (88), Expect = 0.012
Identities = 46/190 (24%), Positives = 62/190 (32%), Gaps = 60/190 (31%)
Query: 128 PDLFQWLCSD----------SLKLCCPAGTFGPSC---LPCPGGTERPCGGYGQCEGEGT 174
PD CSD S + C G GPSC P PC + C+ T
Sbjct: 2007 PDCLPCGCSDHGQCDDGITGSGQCLCETGWTGPSCDTQAVLPAVCTPPCSAHATCKENNT 2066
Query: 175 RGGSGHCDCQAGYGGEA--------CGQCGLGYFEAER---NASHLVCSACFG------- 216
C+C Y G+ C Q G + R + + CS G
Sbjct: 2067 ------CECNLDYEGDGITCTVVDFCKQDNGGCAKVARCSQKGTKVSCSCQKGYKGDGHS 2120
Query: 217 -----PCA-------------RCSGPEESNCLQCKKGWALHHLKC----VDIDECGTEGA 254
PCA + +GP + C +CK + L C + ID C +
Sbjct: 2121 CTEIDPCADGLNGGCHEHATCKMTGPGKHKC-ECKSHYVGDGLNCEPEQLPIDRCLQDNG 2179
Query: 255 NCGADQFCVN 264
C AD CV+
Sbjct: 2180 QCHADAKCVD 2189
Score = 32.7 bits (73), Expect = 0.63
Identities = 32/123 (26%), Positives = 46/123 (37%), Gaps = 27/123 (21%)
Query: 216 GPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCA 275
G C CS S C + AL +CV G+ + C ++C T +C
Sbjct: 675 GTCVSCSLVYWSRCPANSEPTALFTHRCVYSGRFGSLKSGCA--RYCNATVKIPKC---- 728
Query: 276 KACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGY-RCICAE 334
C G C +C G+ + C G N QC ++ GG CIC E
Sbjct: 729 -----CKGFYGPDCNQCPGGF--------------SNPCSG-NGQCADSLGGNGTCICEE 768
Query: 335 GYK 337
G++
Sbjct: 769 GFQ 771
>gi|166362728 epidermal growth factor (beta-urogastrone) [Homo
sapiens]
Length = 1207
Score = 87.4 bits (215), Expect = 2e-17
Identities = 53/127 (41%), Positives = 59/127 (46%), Gaps = 21/127 (16%)
Query: 219 ARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCG-ADQFCVNTEGSYECRDCAKA 277
ARC E QC KG+A C DIDEC C A C+NTEG Y CR
Sbjct: 844 ARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCR----- 898
Query: 278 CLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECET-EVCPGENKQCENTEGGYRCICAEGY 336
CS GYQ G CLD+DEC+ E GEN C NTEGGY C+CA
Sbjct: 899 --------------CSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRL 944
Query: 337 KQMEGIC 343
+ IC
Sbjct: 945 SEPGLIC 951
Score = 56.6 bits (135), Expect = 4e-08
Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 163 CGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCS 222
C Y +C EG C C G+ G+ G ++ + + C ++C
Sbjct: 840 CSMYARCISEGE---DATCQCLKGFAGD-------GKLCSDIDECEMGVPVCPPASSKCI 889
Query: 223 GPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
E +C +G+ + C+DIDEC +CG + C NTEG Y C
Sbjct: 890 NTEGGYVCRCSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTC 938
Score = 38.5 bits (88), Expect = 0.012
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 28/132 (21%)
Query: 210 VCSACFGPCAR--CSGPEESNCLQCKKGWALHHLK--CVDIDECGTEGANCGADQFCVNT 265
+C G C+ C +S+ C +G+AL + C D++EC C C NT
Sbjct: 317 LCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLG--CKNT 374
Query: 266 EGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQV--GSKCLDVDECETEVCPGENKQCEN 323
GSY C C G+ + G +C + C V + C
Sbjct: 375 PGSYYC-------------------TCPVGFVLLPDGKRCHQLVSCPRNVSECSH-DCVL 414
Query: 324 TEGGYRCICAEG 335
T G C C EG
Sbjct: 415 TSEGPLCFCPEG 426
Score = 29.3 bits (64), Expect = 7.0
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 3/47 (6%)
Query: 292 CSPGYQQVGSK--CLDVDECETEVCPGENKQCENTEGGYRCICAEGY 336
C+ GY + C DV+EC G C+NT G Y C C G+
Sbjct: 341 CAEGYALSRDRKYCEDVNECAFWN-HGCTLGCKNTPGSYYCTCPVGF 386
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 86.7 bits (213), Expect = 4e-17
Identities = 75/262 (28%), Positives = 100/262 (38%), Gaps = 68/262 (25%)
Query: 138 SLKLCCPAGTF-GPSCLPCPGGTERPCGGYGQCEGEGTR-GGSGHCDCQAGYGGEACGQC 195
S + CP G F L C E G Q E GS CDC+ GY + GQC
Sbjct: 1788 SFRCECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQC 1847
Query: 196 G--------------------LGYFEA------ERNASHLVC--------SAC-FGPCAR 220
+G F + N +C AC G C
Sbjct: 1848 NDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNGTCRN 1907
Query: 221 CSGPEESNCLQCKKGWAL-HHLKCVDIDECGTEGANCGADQFCVNTEGSYECR------- 272
G NC +C G+ L H+ C+D+DEC + N + C+NT GS++C+
Sbjct: 1908 TIG--SFNC-RCNHGFILSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQCQCNEGYEV 1964
Query: 273 --------DCAKACLGCMGAGPGRCKK--------CSPGYQQVGSKCLDVDEC--ETEVC 314
D + L PG C+ C PGY KC D+DEC E E+C
Sbjct: 1965 APDGRTCVDINECLLEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEIC 2024
Query: 315 PGENKQCENTEGGYRCICAEGY 336
C NTEG ++C+C EG+
Sbjct: 2025 --ALGTCSNTEGSFKCLCPEGF 2044
Score = 81.6 bits (200), Expect = 1e-15
Identities = 56/177 (31%), Positives = 66/177 (37%), Gaps = 42/177 (23%)
Query: 167 GQCEGEGTRGGSGHCDCQAGYGGEA-------CGQCGLGYFEAERNASHLVCSACFGPCA 219
G CE GS C C GY G+ +C +G A H VC+ G
Sbjct: 1294 GTCENTK---GSFICHCDMGYSGKKGKTGCTDINECEIG---AHNCGKHAVCTNTAGSF- 1346
Query: 220 RCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACL 279
+CS C GW +KC D+DEC C C NT GSY C
Sbjct: 1347 KCS---------CSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCL------- 1390
Query: 280 GCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGY 336
C GY G C D+DEC + N QC N GGYRC C G+
Sbjct: 1391 ------------CKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGF 1435
Score = 78.2 bits (191), Expect = 1e-14
Identities = 60/188 (31%), Positives = 82/188 (43%), Gaps = 44/188 (23%)
Query: 177 GSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCA--RCSGPEESNCLQCKK 234
GS C+C G+ + G+C + E E+N PCA C + S QC+
Sbjct: 470 GSCRCECNKGFQLDLRGEC-IDVDECEKN-----------PCAGGECINNQGSYTCQCRA 517
Query: 235 GW--ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC------------RDCA----- 275
G+ L +C DIDEC G C + C+NT+GS+ C ++C
Sbjct: 518 GYQSTLTRTECRDIDECLQNGRICNNGR-CINTDGSFHCVCNAGFHVTRDGKNCEDMDEC 576
Query: 276 ---KACLGCMGAGPGRCKKC--SPGYQQV--GSKCLDVDECETE-VCPGENKQCENTEGG 327
CL M KC PG+Q G C D++ECET +C N +C NT+G
Sbjct: 577 SIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGIC--MNGRCVNTDGS 634
Query: 328 YRCICAEG 335
YRC C G
Sbjct: 635 YRCECFPG 642
Score = 77.4 bits (189), Expect = 2e-14
Identities = 58/193 (30%), Positives = 80/193 (41%), Gaps = 41/193 (21%)
Query: 167 GQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCAR-CSGPE 225
G+C + GS HC C+ GY + G + E C+ PC C E
Sbjct: 2416 GECVNDR---GSYHCICKTGYTPDITGTSCVDLNE---------CNQAPKPCNFICKNTE 2463
Query: 226 ESNCLQCKKGWALHH--LKCVDIDECGTEGANCGADQF-CVNTEGSYECRDCAKACLGCM 282
S C KG+ L C D+DEC T+ NC QF CVNT G + C
Sbjct: 2464 GSYQCSCPKGYILQEDGRSCKDLDECATKQHNC---QFLCVNTIGGFTC----------- 2509
Query: 283 GAGPGRCKKCSPGYQQVGSKCLDVDECETEV--CPGENKQCENTEGGYRCICAEGYKQME 340
KC PG+ Q + C+D +EC +++ C G C+NT G + C C G+ +
Sbjct: 2510 --------KCPPGFTQHHTSCIDNNECTSDINLC-GSKGICQNTPGSFTCECQRGFSLDQ 2560
Query: 341 GICVKEQIPESAG 353
E + E G
Sbjct: 2561 TGSSCEDVDECEG 2573
Score = 73.2 bits (178), Expect = 4e-13
Identities = 53/168 (31%), Positives = 68/168 (40%), Gaps = 32/168 (19%)
Query: 177 GSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGW 236
GS C+C G+ + E E +A HL P RC C G+
Sbjct: 1134 GSYRCECPPGHQLSPNISACIDINECELSA-HLC------PNGRCVNLIGKYQCACNPGY 1186
Query: 237 --ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSP 294
L CVDIDEC N G + FC N+EGSYEC C P
Sbjct: 1187 HSTPDRLFCVDIDECSI--MNGGCETFCTNSEGSYEC-------------------SCQP 1225
Query: 295 GYQQVGSK--CLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQME 340
G+ + + C D+DECE + QC N G YRC+C +G+ E
Sbjct: 1226 GFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASE 1273
Score = 72.0 bits (175), Expect = 9e-13
Identities = 55/187 (29%), Positives = 72/187 (38%), Gaps = 53/187 (28%)
Query: 181 CDCQAGYGGEACGQC--------------GLGY----------FEAERNASHLVCSAC-F 215
C A +G E C +C G G+ F + N ++ S C
Sbjct: 982 CSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIPSLCTH 1041
Query: 216 GPCARCSGPEESNCLQCKKGWAL--HHLKCVDIDECGTEGANCGADQFCVNTEGSYECRD 273
G C G S +C G+AL C DIDEC CG Q CVNT G +EC
Sbjct: 1042 GKCRNTIG---SFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQ-CVNTPGDFEC-- 1095
Query: 274 CAKACLGCMGAGPGRCKKCSPGYQQ---VGSKCLDVDECETEVCPGENKQCENTEGGYRC 330
KC GY+ + C+D+DEC+ + C NTEG YRC
Sbjct: 1096 -----------------KCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSYRC 1138
Query: 331 ICAEGYK 337
C G++
Sbjct: 1139 ECPPGHQ 1145
Score = 68.9 bits (167), Expect = 8e-12
Identities = 58/204 (28%), Positives = 79/204 (38%), Gaps = 53/204 (25%)
Query: 166 YGQCEGEGTRGGSGHCDCQAGY--GGEAC---GQCGLGYFEAERNASHLVCSACF-GPCA 219
+GQC GS C+C GY G C +C +G + C G C
Sbjct: 2139 HGQCINTD---GSYRCECPFGYILAGNECVDTDECSVG-------------NPCGNGTCK 2182
Query: 220 RCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECR------- 272
G E C + + + + C DI+EC C CVNT GSYEC+
Sbjct: 2183 NVIGGFECTCEEGFEPGPM--MTCEDINECAQNPLLCAFR--CVNTYGSYECKCPVGYVL 2238
Query: 273 ------------------DCAKACLGCMGAGPGRCKKCSPGYQQV--GSKCLDVDECETE 312
DC + + C C PGYQ+ G C+D +EC+T+
Sbjct: 2239 REDRRMCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTK 2298
Query: 313 VCPGENKQCENTEGGYRCICAEGY 336
EN +C NT G Y C C +G+
Sbjct: 2299 PGICENGRCLNTRGSYTCECNDGF 2322
Score = 67.8 bits (164), Expect = 2e-11
Identities = 69/255 (27%), Positives = 87/255 (34%), Gaps = 82/255 (32%)
Query: 135 CSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGS---GHCDCQAGYGGEA 191
CS CP+G PSC G+ C GGS HC CQ GY G
Sbjct: 94 CSRPNMCTCPSGQIAPSC-----GSR----SIQHCNIRCMNGGSCSDDHCLCQKGYIGTH 144
Query: 192 CGQ--CGLGYFEAERNASHLVCSACFG-------------PC------ARCSG------- 223
CGQ C G R + C+ +G PC C G
Sbjct: 145 CGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVC 204
Query: 224 ---------------PEESNCLQ---CKKGWA--LHHLKCVDIDECGTEGANCGADQFCV 263
P E Q C++G+ + C D+DEC C C+
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGN-CI 263
Query: 264 NTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQ--QVGSKCLDVDECETEVCPGENKQC 321
NT GS+EC KC G++ +V KC D+DEC T E +C
Sbjct: 264 NTVGSFEC-------------------KCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC 304
Query: 322 ENTEGGYRCICAEGY 336
NT Y C C G+
Sbjct: 305 TNTVSSYFCKCPPGF 319
Score = 67.8 bits (164), Expect = 2e-11
Identities = 58/187 (31%), Positives = 77/187 (41%), Gaps = 39/187 (20%)
Query: 163 CGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCS 222
CG G C+ GS C+CQ G+ + G E E N C C
Sbjct: 2535 CGSKGICQNTP---GSFTCECQRGFSLDQTGSSCEDVDECEGN------HRCQHGCQNII 2585
Query: 223 GPEESNCLQCKKGWALHHL--KCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLG 280
G +C Q G+ H+ +CVD +EC + GA C NT GSY+C
Sbjct: 2586 GGYRCSCPQ---GYLQHYQWNQCVDENECLSAHICGGAS--CHNTLGSYKCM-------- 2632
Query: 281 CMGAGPGRCKKCSPG--YQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQ 338
C G Y+Q C D++EC + P + C NTEGGY C C GY +
Sbjct: 2633 -----------CPAGFQYEQFSGGCQDINECGSAQAPC-SYGCSNTEGGYLCGCPPGYFR 2680
Query: 339 M-EGICV 344
+ +G CV
Sbjct: 2681 IGQGHCV 2687
Score = 64.7 bits (156), Expect = 2e-10
Identities = 55/186 (29%), Positives = 70/186 (37%), Gaps = 33/186 (17%)
Query: 168 QCEGEGTRGGSGHCDCQAGYGGEACGQ-CGLGYFEAERNASHLVCSACFGPC--ARCSGP 224
+C +G RG HC+ G A + C G A C C C
Sbjct: 2362 ECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGECVND 2421
Query: 225 EESNCLQCKKGWA--LHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCM 282
S CK G+ + CVD++EC C C NTEGSY+C
Sbjct: 2422 RGSYHCICKTGYTPDITGTSCVDLNECNQAPKPCNF--ICKNTEGSYQC----------- 2468
Query: 283 GAGPGRCKKCSPGY--QQVGSKCLDVDECETEVCPGENKQ--CENTEGGYRCICAEGYKQ 338
C GY Q+ G C D+DEC T+ N Q C NT GG+ C C G+ Q
Sbjct: 2469 --------SCPKGYILQEDGRSCKDLDECATKQ---HNCQFLCVNTIGGFTCKCPPGFTQ 2517
Query: 339 MEGICV 344
C+
Sbjct: 2518 HHTSCI 2523
Score = 61.6 bits (148), Expect = 1e-09
Identities = 68/250 (27%), Positives = 86/250 (34%), Gaps = 78/250 (31%)
Query: 155 CPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGY----GGEACGQCGLGYFEAERNASHLV 210
C G C GQC GS C C GY G C E + A
Sbjct: 1934 CASGNGNLCRN-GQCINTV---GSFQCQCNEGYEVAPDGRTCVDINECLLEPRKCAP--- 1986
Query: 211 CSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYE 270
G C G C+ C G++L + KC DIDEC E C C NTEGS++
Sbjct: 1987 -----GTCQNLDG--SYRCI-CPPGYSLQNEKCEDIDECVEEPEICALGT-CSNTEGSFK 2037
Query: 271 C------------RDCA---------------------------KACLGCMGAGPGR-CK 290
C R C + C G G G C+
Sbjct: 2038 CLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCE 2097
Query: 291 KC----SPGYQQV-----------GSKCLDVDEC-ETEVCPGENKQCENTEGGYRCICAE 334
C ++Q+ +D+DEC E +VC ++ QC NT+G YRC C
Sbjct: 2098 LCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVC--KHGQCINTDGSYRCECPF 2155
Query: 335 GYKQMEGICV 344
GY CV
Sbjct: 2156 GYILAGNECV 2165
Score = 61.6 bits (148), Expect = 1e-09
Identities = 54/186 (29%), Positives = 72/186 (38%), Gaps = 47/186 (25%)
Query: 177 GSGHCDCQAGYG----GEACGQCGLGYFEAE-----------RNASHLVCSACF------ 215
GS C C G+ G C + Y A+ RN S C
Sbjct: 2034 GSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWG 2093
Query: 216 GPCARC-SGPEESNCLQCKKGWAL---HHLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
PC C + P+E+ C G + VD+DEC E C Q C+NT+GSY C
Sbjct: 2094 DPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDEC-KEPDVCKHGQ-CINTDGSYRC 2151
Query: 272 RDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCI 331
+C GY G++C+D DEC P N C+N GG+ C
Sbjct: 2152 -------------------ECPFGYILAGNECVDTDECSVGN-PCGNGTCKNVIGGFECT 2191
Query: 332 CAEGYK 337
C EG++
Sbjct: 2192 CEEGFE 2197
Score = 60.8 bits (146), Expect = 2e-09
Identities = 37/120 (30%), Positives = 54/120 (45%), Gaps = 25/120 (20%)
Query: 220 RCSGPEESNCLQCKKGWALH-HLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKAC 278
RC S +C KG+ L +C+D+DEC E C + C+N +GSY C+
Sbjct: 464 RCIPTPGSCRCECNKGFQLDLRGECIDVDEC--EKNPCAGGE-CINNQGSYTCQ------ 514
Query: 279 LGCMGAGPGRCKKCSPGYQQV--GSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGY 336
C GYQ ++C D+DEC N +C NT+G + C+C G+
Sbjct: 515 -------------CRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGF 561
Score = 57.8 bits (138), Expect = 2e-08
Identities = 56/223 (25%), Positives = 76/223 (34%), Gaps = 54/223 (24%)
Query: 161 RPCGGYGQCEGEG--------TRGGSGHCDCQAG-------------------YGGEACG 193
R C +CE G GS C+C G YGG G
Sbjct: 609 RYCKDINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRG 668
Query: 194 QCGLGYFEAERNASHLVCSA--CFG-PCARCSGPEESNCLQ-CKKGWALHHLKCVDIDEC 249
QC F A + S FG PC C + C G + DI+EC
Sbjct: 669 QCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGS-DINEC 727
Query: 250 GTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQ--QVGSKCLDVD 307
+ C + C N G+Y+C C+ GY+ G C+D++
Sbjct: 728 ALDPDIC-PNGICENLRGTYKCI-------------------CNSGYEVDSTGKNCVDIN 767
Query: 308 ECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPE 350
EC +N QC NT G + C C +G+ + E I E
Sbjct: 768 ECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDE 810
Score = 56.6 bits (135), Expect = 4e-08
Identities = 60/236 (25%), Positives = 79/236 (33%), Gaps = 65/236 (27%)
Query: 147 TFGPSCLPCPGG-----TERPCGGYGQCEGEGTRG--------GSGHCDCQAGY----GG 189
TFG CP G R C +CE G G G+ C C Y GG
Sbjct: 1625 TFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQVNGG 1684
Query: 190 EAC-----GQCGLGYFEAER--------NASHLVCSACFG-------PCARCSGPEESN- 228
C C Y+ + N + +C + PC +C P
Sbjct: 1685 NNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDEF 1744
Query: 229 ---CLQCKKGWALHHLKC--VDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMG 283
C + G+ + VDIDEC C + C+N GS+ C
Sbjct: 1745 ATLCGSQRPGFVIDIYTGLPVDIDECREIPGVC-ENGVCINMVGSFRC------------ 1791
Query: 284 AGPGRCKKCSPG--YQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
+C G Y C D+DEC+ N +C NT G YRC C GY+
Sbjct: 1792 -------ECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYR 1840
Score = 56.2 bits (134), Expect = 5e-08
Identities = 72/273 (26%), Positives = 98/273 (35%), Gaps = 94/273 (34%)
Query: 142 CCPAGT---FGPSCLPCP--------------------GGTERPCG------GYGQCEGE 172
CC A T FG C PCP G C G CE
Sbjct: 683 CCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICEN- 741
Query: 173 GTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQC 232
G+ C C +GY ++ G+ + E N+ L+C G C G S C
Sbjct: 742 --LRGTYKCICNSGYEVDSTGKNCVDINECVLNS--LLCDN--GQCRNTPG---SFVCTC 792
Query: 233 KKGWALH-HLK-CVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLG-----CMGAG 285
KG+ LK C DIDEC E + C + C N+ GS+ C +++ L C+
Sbjct: 793 PKGFIYKPDLKTCEDIDEC--ESSPC-INGVCKNSPGSFICECSSESTLDPTKTICIETI 849
Query: 286 PGRCKK----------------------------------------CSPGYQQV-GSKCL 304
G C + C GY ++ G++C
Sbjct: 850 KGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE 909
Query: 305 DVDECETEVCPG--ENKQCENTEGGYRCICAEG 335
D+DEC EV PG +N C NT G ++C C G
Sbjct: 910 DIDEC--EVFPGVCKNGLCVNTRGSFKCQCPSG 940
Score = 53.9 bits (128), Expect = 3e-07
Identities = 62/224 (27%), Positives = 88/224 (39%), Gaps = 42/224 (18%)
Query: 135 CSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGE-----GTRGGSGHCDCQ--AGY 187
C+D + P +C+ PG C + TR G+ + D +
Sbjct: 1485 CTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDN 1544
Query: 188 GGEACG-QCGLGYFEAERNASHLVCSACFGPCARCSGPEESNC-LQCK--KGWALHHLKC 243
G AC + G+G +A S + A PC C S + C +G+ + +
Sbjct: 1545 GDTACSNEIGVGVSKASCCCS--LGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITV 1602
Query: 244 V--DIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGY--QQV 299
+ DIDEC C + C+NT GS++CR C GY +
Sbjct: 1603 ILEDIDECQELPGLCQGGK-CINTFGSFQCR-------------------CPTGYYLNED 1642
Query: 300 GSKCLDVDECETE-VC-PGENKQCENTEGGYRCICAEGYKQMEG 341
C DV+ECET +C PG C NT G Y CIC Y Q+ G
Sbjct: 1643 TRVCDDVNECETPGICGPGT---CYNTVGNYTCICPPDYMQVNG 1683
Score = 50.8 bits (120), Expect = 2e-06
Identities = 23/54 (42%), Positives = 33/54 (61%), Gaps = 4/54 (7%)
Query: 286 PGRCK-KCSPGYQ-QVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
PG C+ +C+ G+Q + +C+DVDECE C G +C N +G Y C C GY+
Sbjct: 469 PGSCRCECNKGFQLDLRGECIDVDECEKNPCAGG--ECINNQGSYTCQCRAGYQ 520
Score = 49.3 bits (116), Expect = 7e-06
Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 34/257 (13%)
Query: 135 CSDSLKLCC--PAGTFGPSCLPCPGG-----TERPCGGYGQCEGEGTRGGSGHCDCQAGY 187
C+ + LC T+G CP G R C +CE +C+
Sbjct: 2210 CAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQMECKNLI 2269
Query: 188 GGEACGQCGLGYF---EAERNASHLVCSACFGPC--ARCSGPEESNCLQCKKGWAL--HH 240
G C CG GY + E C G C RC S +C G+ +
Sbjct: 2270 GTYMC-ICGPGYQRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQ 2328
Query: 241 LKCVDIDE--CGTEGAN--CGADQFCVNTEGSYEC-----RDCAKACLGCMGAGPGRCKK 291
+C+D E C TE C N EC R C C G KK
Sbjct: 2329 DECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKK 2388
Query: 292 CSPGYQQVGSKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGY-KQMEGI-CVK-- 345
P + + D+DEC+ +VC N +C N G Y CIC GY + G CV
Sbjct: 2389 LCPHGRGFMTNGADIDECKVIHDVC--RNGECVNDRGSYHCICKTGYTPDITGTSCVDLN 2446
Query: 346 --EQIPESAGFFSEMTE 360
Q P+ F + TE
Sbjct: 2447 ECNQAPKPCNFICKNTE 2463
Score = 40.4 bits (93), Expect = 0.003
Identities = 70/316 (22%), Positives = 95/316 (30%), Gaps = 117/316 (37%)
Query: 145 AGTFGPSCLP--------------CPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGE 190
AG+F SC P C GT C + C+ GS C C+ GY G+
Sbjct: 1343 AGSFKCSCSPGWIGDGIKCTDLDECSNGTHM-CSQHADCKNTM---GSYRCLCKEGYTGD 1398
Query: 191 A--------CGQ----CGLGYFEAERNASHLVCSACFGPCA---------RCSGPEE--- 226
C + CG G C F P A CS P
Sbjct: 1399 GFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDECSLPNICVF 1458
Query: 227 SNC--------LQCKKGWALHHL--KCVDIDECGTEGANCGADQFCVNTEGSYECRDCAK 276
C +C+ G+ L C D++EC + C + CVNT GSY C DC
Sbjct: 1459 GTCHNLPGLFRCECEIGYELDRSGGNCTDVNEC-LDPTTCISGN-CVNTPGSYIC-DCPP 1515
Query: 277 --------------------------------ACLGCMGAGPGRCKKCSPGYQQVGSKCL 304
AC +G G + C + G+ C
Sbjct: 1516 DFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCE 1575
Query: 305 ------------------------------DVDECETEVCPGENKQCENTEGGYRCICAE 334
D+DEC+ + +C NT G ++C C
Sbjct: 1576 MCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGSFQCRCPT 1635
Query: 335 GYKQMEGICVKEQIPE 350
GY E V + + E
Sbjct: 1636 GYYLNEDTRVCDDVNE 1651
Score = 37.7 bits (86), Expect = 0.020
Identities = 49/204 (24%), Positives = 68/204 (33%), Gaps = 66/204 (32%)
Query: 211 CSACFGPC--ARCSGPEESNCLQCKKGWALHH--LKCVDIDECGTEGANCGADQFCVNTE 266
C G C +C S +C G+ L+ C D++EC T G CG C NT
Sbjct: 1610 CQELPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGI-CGPGT-CYNTV 1667
Query: 267 GSYEC------------RDCA---------------KACLG-----------CMGAGPGR 288
G+Y C +C + C G C GR
Sbjct: 1668 GNYTCICPPDYMQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGR 1727
Query: 289 -----CKKCS-PGYQQVGSKC----------------LDVDECETEVCPGENKQCENTEG 326
C++C P + + C +D+DEC EN C N G
Sbjct: 1728 AWNKPCEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVG 1787
Query: 327 GYRCICAEGYKQMEGICVKEQIPE 350
+RC C G+ + + V E I E
Sbjct: 1788 SFRCECPVGFFYNDKLLVCEDIDE 1811
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 85.1 bits (209), Expect = 1e-16
Identities = 84/310 (27%), Positives = 117/310 (37%), Gaps = 82/310 (26%)
Query: 151 SCLPCPG------GTERPCGGYGQCEGEGTRGG--------SGHCDCQAGY--------- 187
SC PG G + C +CE G G S HC+C GY
Sbjct: 910 SCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQ 969
Query: 188 --------------------GGEACGQCGLGYFEAERNASHLVCSACFGP--CA--RCSG 223
G C C GY ++ S + + C P CA +C+
Sbjct: 970 DINECRHPGTCPDGRCVNSPGSYTCLACEEGY--RGQSGSCVDVNECLTPGVCAHGKCTN 1027
Query: 224 PEESNCLQCKKGWAL--HHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAK----- 276
E S C++G+ + C D+DEC + A+C C+NTEGS+ C C
Sbjct: 1028 LEGSFRCSCEQGYEVTSDEKGCQDVDECASR-ASCPTG-LCLNTEGSFACSACENGYWVN 1085
Query: 277 ----ACLG--------------CMG-AGPGRCKKCSPGYQQ--VGSKCLDVDECETEVCP 315
AC C AG CK C GY+ +G C DVDECE
Sbjct: 1086 EDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSS 1145
Query: 316 GENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTEDELVVLQQMFFGIII 375
+C+NT G Y+C+C +G++ G V E + E G E + FF +
Sbjct: 1146 CLGGECKNTVGSYQCLCPQGFQLANG-TVCEDVNECMGEEHCAPHGECLNSHGSFF--CL 1202
Query: 376 CALATLAAKG 385
CA ++A+G
Sbjct: 1203 CAPGFVSAEG 1212
Score = 80.1 bits (196), Expect = 3e-15
Identities = 67/219 (30%), Positives = 88/219 (40%), Gaps = 38/219 (17%)
Query: 135 CSDSLKLC----CPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHC----DCQAG 186
C D C C CL CP G + G CE G HC +C
Sbjct: 1139 CEDPQSSCLGGECKNTVGSYQCL-CPQGFQLANGTV--CEDVNECMGEEHCAPHGECLNS 1195
Query: 187 YGGEACGQCGLGYFEAERNASHLVCSACF--GPCA--RCSGPEES-NCLQCKKGW--ALH 239
+G C C G+ AE S C PC C E S NCL C+ G+ +
Sbjct: 1196 HGSFFC-LCAPGFVSAEGGTSCQDVDECATTDPCVGGHCVNTEGSFNCL-CETGFQPSPE 1253
Query: 240 HLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQV 299
+CVDIDEC G C N+ GSY C LGC PG+
Sbjct: 1254 SGECVDIDECEDYGDPVCGTWKCENSPGSYRC------VLGCQ-----------PGFHMA 1296
Query: 300 -GSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
C+D+DEC + G + C+NT+G +RC+C +G++
Sbjct: 1297 PNGDCIDIDECANDTMCGSHGFCDNTDGSFRCLCDQGFE 1335
Score = 70.9 bits (172), Expect = 2e-12
Identities = 59/210 (28%), Positives = 84/210 (40%), Gaps = 50/210 (23%)
Query: 177 GSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEES-NCLQCKKG 235
GS C C+ GY + + G + + AS C P C E S C C+ G
Sbjct: 1030 GSFRCSCEQGYEVTSDEK---GCQDVDECASRASC-----PTGLCLNTEGSFACSACENG 1081
Query: 236 WALHH--LKCVDIDECGTEGANCGADQFCVNTEGSYECRDC------------------- 274
+ ++ C D+DEC G C + C NT GS+ C+DC
Sbjct: 1082 YWVNEDGTACEDLDECAFPGV-CPSG-VCTNTAGSFSCKDCDGGYRPSPLGDSCEDVDEC 1139
Query: 275 ---AKACLGCMGAGPGRCKK--------CSPGYQQV-GSKCLDVDECETEVCPGENKQCE 322
+CLG G CK C G+Q G+ C DV+EC E + +C
Sbjct: 1140 EDPQSSCLG------GECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECL 1193
Query: 323 NTEGGYRCICAEGYKQMEGICVKEQIPESA 352
N+ G + C+CA G+ EG + + E A
Sbjct: 1194 NSHGSFFCLCAPGFVSAEGGTSCQDVDECA 1223
Score = 70.5 bits (171), Expect = 3e-12
Identities = 68/256 (26%), Positives = 96/256 (37%), Gaps = 70/256 (27%)
Query: 131 FQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGY--- 187
+Q LC +L GT C G E C +G+C GS C C G+
Sbjct: 1158 YQCLCPQGFQLA--NGTVCEDVNECMG--EEHCAPHGECLNSH---GSFFCLCAPGFVSA 1210
Query: 188 -GGEACGQ---------CGLGYFEAERNASHLVCSACFGPCA------------------ 219
GG +C C G+ + + +C F P
Sbjct: 1211 EGGTSCQDVDECATTDPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPV 1270
Query: 220 ----RC-SGPEESNC-LQCKKGWALH-HLKCVDIDECGTEGANCGADQFCVNTEGSYECR 272
+C + P C L C+ G+ + + C+DIDEC + CG+ FC NT+GS+ C
Sbjct: 1271 CGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECAND-TMCGSHGFCDNTDGSFRCL 1329
Query: 273 DCAKACLGCMGAGPGRCKKCSPGYQ--QVGSKCLDVDECETEVCPGENKQCENTEGGYRC 330
C G++ G C+DV+ECE + CEN EG + C
Sbjct: 1330 -------------------CDQGFEISPSGWDCVDVNECELMLAVCGAALCENVEGSFLC 1370
Query: 331 ICA---EGYKQMEGIC 343
+CA E Y EG C
Sbjct: 1371 LCASDLEEYDAQEGHC 1386
Score = 59.7 bits (143), Expect = 5e-09
Identities = 54/202 (26%), Positives = 67/202 (33%), Gaps = 43/202 (21%)
Query: 142 CCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYG-----GEACGQCG 196
C P G G S P G P C G GH C + G E C G
Sbjct: 1386 CRPRGAGGQSMSEAPTGDHAPAPTRMDCYS----GQKGHAPCSSVLGRNTTQAECCCTQG 1441
Query: 197 LGYFEAERNASHLVCSACFGP-CARCSG--PEESNCLQCKKGWALHHLKCVDIDECGTEG 253
+ +A C C A S P + + W D DEC G
Sbjct: 1442 ASWGDA--------CDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFG 1493
Query: 254 ANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGS--KCLDVDECET 311
+ C+NT Y C C+PG+ S KC D DEC+
Sbjct: 1494 PGLCPNGRCLNTVPGYVCL-------------------CNPGFHYDASHKKCEDHDECQD 1534
Query: 312 EVCPGENKQCENTEGGYRCICA 333
C EN +C NTEG + C C+
Sbjct: 1535 LAC--ENGECVNTEGSFHCFCS 1554
Score = 59.3 bits (142), Expect = 6e-09
Identities = 43/128 (33%), Positives = 55/128 (42%), Gaps = 31/128 (24%)
Query: 216 GPCARCSGPEESNCLQCKKGWALHHLK--CVDIDECGTEGANCGADQFCVNTEGSYECRD 273
GP + P+ C+ C G+ LH + C D +EC + C C+N GSY C
Sbjct: 857 GPGTCVNLPDGYRCV-CSPGYQLHPSQAYCTDDNECLRDP--CKGKGRCINRVGSYSC-- 911
Query: 274 CAKACLGCMGAGPGRCKKCSPGYQQVGS----KCLDVDECETE-VCPGENKQCENTEGGY 328
C PGY S +C D++ECE VC G QC NTEG Y
Sbjct: 912 -----------------FCYPGYTLATSGATQECQDINECEQPGVCSG--GQCTNTEGSY 952
Query: 329 RCICAEGY 336
C C +GY
Sbjct: 953 HCECDQGY 960
Score = 43.1 bits (100), Expect = 5e-04
Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 12/119 (10%)
Query: 154 PCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSA 213
P P RP G G+C G + + + CG G + +C+
Sbjct: 539 PLPPAAPRPRGLLGRCYLNTVNGQCANPLLELTTQEDCCGSVGAFW-------GVTLCAP 591
Query: 214 CFGPCARCSGPEESNCLQCKKGWA-LHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
C P S E+ L+C +G+ L+ C DI+EC T G A+ CVNT GSY C
Sbjct: 592 C--PPRPASPVIENGQLECPQGYKRLNLTHCQDINECLTLGLCKDAE--CVNTRGSYLC 646
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/75 (34%), Positives = 33/75 (44%), Gaps = 13/75 (17%)
Query: 275 AKACLGCMGAGPGRCKKCSPGY----------QQVGSKCLDVDECETEVCPGE---NKQC 321
A+ C G GRC + GY C+DV+EC+ P + C
Sbjct: 1734 AEECGILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECDDLNGPAVLCVHGYC 1793
Query: 322 ENTEGGYRCICAEGY 336
ENTEG YRC C+ GY
Sbjct: 1794 ENTEGSYRCHCSPGY 1808
Score = 41.2 bits (95), Expect = 0.002
Identities = 33/116 (28%), Positives = 47/116 (40%), Gaps = 22/116 (18%)
Query: 178 SGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWA 237
+ H + AG+ G +CG + + C RC E C +G+
Sbjct: 1720 ASHPEPPAGFEGLQAEECG-------------ILNGCEN--GRCVRVREGYTCDCFEGFQ 1764
Query: 238 LH--HLKCVDIDECGTEG--ANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRC 289
L H+ CVD++EC A +C NTEGSY C C+ + AGP C
Sbjct: 1765 LDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCH-CSPGYVA--EAGPPHC 1817
Score = 35.8 bits (81), Expect = 0.075
Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 4/47 (8%)
Query: 291 KCSPGYQQVG-SKCLDVDECET-EVCPGENKQCENTEGGYRCICAEG 335
+C GY+++ + C D++EC T +C ++ +C NT G Y C C G
Sbjct: 607 ECPQGYKRLNLTHCQDINECLTLGLC--KDAECVNTRGSYLCTCRPG 651
Score = 31.6 bits (70), Expect = 1.4
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 7/36 (19%)
Query: 306 VDECE---TEVC-PGENKQCENTEGGYRCICAEGYK 337
+D C T VC PG C N GYRC+C+ GY+
Sbjct: 845 IDRCAAGATNVCGPGT---CVNLPDGYRCVCSPGYQ 877
Score = 29.6 bits (65), Expect = 5.4
Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 5/35 (14%)
Query: 305 DVDECET---EVCPGENKQCENTEGGYRCICAEGY 336
D DEC +CP N +C NT GY C+C G+
Sbjct: 1485 DADECVIFGPGLCP--NGRCLNTVPGYVCLCNPGF 1517
Score = 29.3 bits (64), Expect = 7.0
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 4/37 (10%)
Query: 33 PPPQSSPPPQPHPCHTCRGLVDSF----NKGLERTIR 65
P PQS P PQ P T GL + + GL RT+R
Sbjct: 263 PAPQSPPAPQSPPAGTLSGLSQTHPSQQHVGLSRTVR 299
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 80.9 bits (198), Expect = 2e-15
Identities = 65/217 (29%), Positives = 83/217 (38%), Gaps = 36/217 (16%)
Query: 133 WLCSDSLKL--CCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGE 190
+ C+ +++ CCP G FG C PCPGG C G+GQC+ GSG C C G+ G
Sbjct: 1309 YTCAKKIQVPDCCP-GFFGTLCEPCPGGLGGVCSGHGQCQDRFL--GSGECHCHEGFHGT 1365
Query: 191 ACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECG 250
AC C LG + VC G C G + C GW
Sbjct: 1366 ACEVCELGRYGPNCTG---VCDCAHGLCQ--EGLQGDGSCVCNVGW-------------- 1406
Query: 251 TEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDEC- 309
+G C DQ + + +C A AG C C+ GY G C +VD C
Sbjct: 1407 -QGLRC--DQKITSPQCPRKCDPNANCVQD--SAGASTC-ACAAGYSGNGIFCSEVDPCA 1460
Query: 310 --ETEVCPGENKQCENTEGGYR-CICAEGYKQMEGIC 343
P N C G R C C +GY +C
Sbjct: 1461 HGHGGCSPHAN--CTKVAPGQRTCTCQDGYMGDGELC 1495
Score = 80.1 bits (196), Expect = 3e-15
Identities = 61/206 (29%), Positives = 80/206 (38%), Gaps = 33/206 (16%)
Query: 140 KLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQC-GLG 198
K CCP G +G C CPGG E PC G+G C R G+ C CQ + G AC +C
Sbjct: 98 KACCP-GYWGSRCHECPGGAETPCNGHGTCLDGMDRNGT--CVCQENFRGSACQECQDPN 154
Query: 199 YFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGA 258
F + + VCS G C GP C G+ H C E C
Sbjct: 155 RFGPDCQS---VCSCVHGVCNH--GPRGDGSCLCFAGYTGPH--------CDQELPVCQE 201
Query: 259 DQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGEN 318
+ NT+ S E C +C PGY Q GS+C + C C
Sbjct: 202 LRCPQNTQCSAEAPSC----------------RCLPGYTQQGSECRAPNPCWPSPCSLLA 245
Query: 319 KQCENTEGGYRCICAEGYKQMEGICV 344
+ + +G +C C E Y +C+
Sbjct: 246 QCSVSPKGQAQCHCPENYHGDGMVCL 271
Score = 68.2 bits (165), Expect = 1e-11
Identities = 69/235 (29%), Positives = 84/235 (35%), Gaps = 41/235 (17%)
Query: 142 CCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYF- 200
CCP G +G C CPGG PC G C GSG C C++G+ G AC C G F
Sbjct: 1959 CCP-GHYGSECQACPGGPSSPCSDRGVC--MDGMSGSGQCLCRSGFAGTACELCAPGAFG 2015
Query: 201 ---EAERNASHLVCSACFGPCARCSGPEESNCLQCKKGW------ALHHLKCVDIDECGT 251
+A R H C G C C +GW L+ V C
Sbjct: 2016 PHCQACRCTVHGRCDEGLGGSGSCF---------CDEGWTGPRCEVQLELQPVCTPPCAP 2066
Query: 252 EGANCGADQFCVNTEGSYE-----------CRDCAKAC---LGCMGAGPGRCKKCSPGYQ 297
E A C A C + G YE C+D C C G C P Y+
Sbjct: 2067 E-AVCRAGNSCECSLG-YEGDGRVCTVADLCQDGHGGCSEHANCSQVGTMVTCTCLPDYE 2124
Query: 298 QVGSKCLDVDECETEVCPG--ENKQCENTE-GGYRCICAEGYKQMEGICVKEQIP 349
G C + C G E+ C +T RC C GY C++E P
Sbjct: 2125 GDGWSCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESEP 2179
Score = 67.8 bits (164), Expect = 2e-11
Identities = 65/226 (28%), Positives = 84/226 (37%), Gaps = 39/226 (17%)
Query: 143 CPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEA 202
C G FGP C CPGG PC G G C +G + G+G C C Y G AC C
Sbjct: 720 CCKGFFGPDCTQCPGGFSNPCYGKGNC-SDGIQ-GNGACLCFPDYKGIACHICSNPNKHG 777
Query: 203 ERNASHLVCSACFGPCARCSGPEESNCLQ--CKKGWALHHLKCVDIDECGTEG--ANCGA 258
E+ C G C G C Q C G++ + +CG G +C
Sbjct: 778 EQCQED--CGCVHGLCDNRPG-SGGVCQQGTCAPGFSGRFCN-ESMGDCGPTGLAQHCHL 833
Query: 259 DQFCVNTEGSYECRDCAKACLG----CMGAGP------GRCKK---------------CS 293
CV+ EG CR C G C + P G C + C
Sbjct: 834 HARCVSQEGVARCR-CLDGFEGDGFSCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCH 892
Query: 294 PGYQQVGSKCLDVDECETEVCPG--ENKQCENT-EGGYRCICAEGY 336
G+ G C+ +DECE ++ G + C G RC C G+
Sbjct: 893 KGWSGDGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKLGF 938
Score = 39.3 bits (90), Expect = 0.007
Identities = 42/155 (27%), Positives = 54/155 (34%), Gaps = 36/155 (23%)
Query: 154 PCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSA 213
PC C +C G+ HC C G+ G+ G+ + E E +
Sbjct: 864 PCSHPDRGGCSENAECVPGSL--GTHHCTCHKGWSGD--GRVCVAIDECELDMR------ 913
Query: 214 CFGPC---ARCS--GPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGS 268
G C A CS GP +S C CK G+A +C ID C C G
Sbjct: 914 --GGCHTDALCSYVGPGQSRCT-CKLGFAGDGYQCSPIDPCRAGNGGC---------HGL 961
Query: 269 YECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKC 303
CR +G G C C PG+ G C
Sbjct: 962 ATCR--------AVGGGQRVC-TCPPGFGGDGFSC 987
Score = 31.2 bits (69), Expect = 1.8
Identities = 19/53 (35%), Positives = 22/53 (41%), Gaps = 3/53 (5%)
Query: 154 PCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNA 206
PC G C G C G GG C C G+GG+ G + E E NA
Sbjct: 950 PCRAGNGG-CHGLATCRAVG--GGQRVCTCPPGFGGDGFSCYGDIFRELEANA 999
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 80.9 bits (198), Expect = 2e-15
Identities = 69/224 (30%), Positives = 84/224 (37%), Gaps = 60/224 (26%)
Query: 142 CCPAGT-FGPSCLPCP-GGTER-----PCGGYGQCEGEGTRG-----------------G 177
CC G +GP C CP GT P G EG G
Sbjct: 2325 CCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINSLG 2384
Query: 178 SGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCA-RCSGPEESNCLQCKKGW 236
S C CQAGY +A L E CS PC C + S C +G+
Sbjct: 2385 SFRCHCQAGYTPDATATTCLDMDE---------CSQVPKPCTFLCKNTKGSFLCSCPRGY 2435
Query: 237 ALHH--LKCVDIDECGTEGANCGADQF-CVNTEGSYECRDCAKACLGCMGAGPGRCKKCS 293
L C D+DEC + NC QF CVNT G++ CR C
Sbjct: 2436 LLEEDGRTCKDLDECTSRQHNC---QFLCVNTVGAFTCR-------------------CP 2473
Query: 294 PGYQQVGSKCLDVDECETEVCP-GENKQCENTEGGYRCICAEGY 336
PG+ Q C D DEC + P G + C NT G +RC C +G+
Sbjct: 2474 PGFTQHHQACFDNDECSAQPGPCGAHGHCHNTPGSFRCECHQGF 2517
Score = 77.8 bits (190), Expect = 2e-14
Identities = 57/194 (29%), Positives = 72/194 (37%), Gaps = 42/194 (21%)
Query: 166 YGQCEGEGTRGGSGHCDCQAGY----GGEACG---QCGLGYFEAERNASHLVCSACFGPC 218
+G CE GS C CQ GY G C +C +G + +AS C
Sbjct: 1251 HGDCENTK---GSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHAS----------C 1297
Query: 219 ARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKAC 278
G CL GW +C D+DEC ++ C C+N GSY C
Sbjct: 1298 LNIPGSFSCRCLP---GWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCT------ 1348
Query: 279 LGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQ 338
C G+ G C D DEC V +N QC N GGYRC C G+
Sbjct: 1349 -------------CRQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDP 1395
Query: 339 MEGICVKEQIPESA 352
E + + E A
Sbjct: 1396 TEDHRACQDVDECA 1409
Score = 73.9 bits (180), Expect = 2e-13
Identities = 54/183 (29%), Positives = 74/183 (40%), Gaps = 36/183 (19%)
Query: 178 SGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWA 237
S C+C GY + G+C + E + H G C G C +
Sbjct: 430 SYRCECNVGYTQDVRGEC-IDVDECTSSPCH------HGDCVNIPGTYHCRCYPGFQATP 482
Query: 238 LHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC------------------RDCAKA-- 277
CVD+DEC G C + CVNTEGS++C +CA +
Sbjct: 483 TRQ-ACVDVDECIVSGGLCHLGR-CVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTM 540
Query: 278 CLG--CMGAGPGRCKKCSPGYQQV--GSKCLDVDECETE-VCPGENKQCENTEGGYRCIC 332
C+ C+ C PG+ G C+D+DEC+T +C N C NTEG +RC C
Sbjct: 541 CVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGIC--VNGHCTNTEGSFRCQC 598
Query: 333 AEG 335
G
Sbjct: 599 LGG 601
Score = 70.5 bits (171), Expect = 3e-12
Identities = 54/199 (27%), Positives = 81/199 (40%), Gaps = 53/199 (26%)
Query: 177 GSGHCDCQAGYGGEACGQCGLGYFEAERNASHL--------VCSACFGPCARCSGPEESN 228
GS HC C G+ +A ERN + + +C G C G E
Sbjct: 1007 GSFHCACAGGFALDA----------QERNCTDIDECRISPDLCGQ--GTCVNTPGSFECE 1054
Query: 229 CLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECR---------------- 272
C + + C+D+DEC + C C NT+GSY+C+
Sbjct: 1055 CFPGYESGFMLMKNCMDVDECARDPLLCRGGT-CTNTDGSYKCQCPPGHELTAKGTACED 1113
Query: 273 --DCAKA--------CLGCMGAGPGRCKKCSPGYQQVGSK--CLDVDECETEVCPGENKQ 320
+C+ + C+ +GA +C C G+Q + C+D++EC + G +
Sbjct: 1114 IDECSLSDGLCPHGQCVNVIGAF--QCS-CHAGFQSTPDRQGCVDINECRVQN-GGCDVH 1169
Query: 321 CENTEGGYRCICAEGYKQM 339
C NTEG YRC C +GY M
Sbjct: 1170 CINTEGSYRCSCGQGYSLM 1188
Score = 69.7 bits (169), Expect = 5e-12
Identities = 74/259 (28%), Positives = 95/259 (36%), Gaps = 57/259 (22%)
Query: 121 FHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGG-----TERPCGGYGQCE----- 170
F+K +F LC+ C T G C GG ER C +C
Sbjct: 983 FYKDVNECKVFPGLCTHGT---C-RNTVGSFHCACAGGFALDAQERNCTDIDECRISPDL 1038
Query: 171 -GEGT---RGGSGHCDCQAGY--GGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGP 224
G+GT GS C+C GY G C + E R+ L+C C+
Sbjct: 1039 CGQGTCVNTPGSFECECFPGYESGFMLMKNC-MDVDECARDP--LLCRG-----GTCTNT 1090
Query: 225 EESNCLQCKKGWAL--HHLKCVDIDECGTEGANCGADQFCVNTEGSYEC----------- 271
+ S QC G L C DIDEC C Q CVN G+++C
Sbjct: 1091 DGSYKCQCPPGHELTAKGTACEDIDECSLSDGLCPHGQ-CVNVIGAFQCSCHAGFQSTPD 1149
Query: 272 -------RDCAKACLGC-----MGAGPGRCKKCSPGYQQV--GSKCLDVDECETEVCPGE 317
+C GC G RC C GY + G C DVDECE +
Sbjct: 1150 RQGCVDINECRVQNGGCDVHCINTEGSYRCS-CGQGYSLMPDGRACADVDECEENPRVCD 1208
Query: 318 NKQCENTEGGYRCICAEGY 336
C N GG+RC+C +G+
Sbjct: 1209 QGHCTNMPGGHRCLCYDGF 1227
Score = 68.9 bits (167), Expect = 8e-12
Identities = 70/264 (26%), Positives = 91/264 (34%), Gaps = 71/264 (26%)
Query: 138 SLKLCCPAG-TFGPSCLPCP-----GGTERPCGGYGQCEGEGTRGGSGHCDCQAGY---- 187
S + CPAG + L C G E PC C GS C C GY
Sbjct: 1743 SFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP---GSYRCKCTRGYKLSP 1799
Query: 188 GGEACGQ---------CGLGYFEAERNASHLVCSACF----------------------G 216
GG G+ C G + +C F G
Sbjct: 1800 GGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMDIDECDRQPCGNG 1859
Query: 217 PCARCSGPEESNCLQCKKGWAL-HHLKCVDIDECGTEGANCGADQFCVNTEGSYEC---- 271
C G NCL C G+ + H+ CVD DEC T C+NT GS+ C
Sbjct: 1860 TCKNIIG--SYNCL-CFPGFVVTHNGDCVDFDECTTLVGQVCRFGHCLNTAGSFHCLCQD 1916
Query: 272 --------RDCAKA--CLGCMGAG-PGRCKK--------CSPGYQQVGSKCLDVDECETE 312
++C CL G PG C+ C PG+Q C+D+DEC E
Sbjct: 1917 GFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSFRCICPPGFQVQSDHCIDIDECSEE 1976
Query: 313 VCPGENKQCENTEGGYRCICAEGY 336
C N+ G ++C+C G+
Sbjct: 1977 PNLCLFGTCTNSPGSFQCLCPPGF 2000
Score = 65.1 bits (157), Expect = 1e-10
Identities = 43/134 (32%), Positives = 54/134 (40%), Gaps = 27/134 (20%)
Query: 211 CSACFGPCAR--CSGPEESNCLQCKKGWAL--HHLKCVDIDECGTEGANCGADQFCVNTE 266
C G C C S C G+AL C DIDEC CG CVNT
Sbjct: 990 CKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQGT-CVNTP 1048
Query: 267 GSYECRDCAKACLGCMGAGPGRCKKCSPGYQQ---VGSKCLDVDECETEVCPGENKQCEN 323
GS+EC +C PGY+ + C+DVDEC + C N
Sbjct: 1049 GSFEC-------------------ECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTN 1089
Query: 324 TEGGYRCICAEGYK 337
T+G Y+C C G++
Sbjct: 1090 TDGSYKCQCPPGHE 1103
Score = 63.9 bits (154), Expect = 3e-10
Identities = 61/234 (26%), Positives = 82/234 (35%), Gaps = 63/234 (26%)
Query: 125 QEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRG------GS 178
QE FQ LC FG +P P + + G T G GS
Sbjct: 2058 QEGSAAFQELCP-----------FGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGS 2106
Query: 179 GHCDCQAGYGGEACG-------QCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQ 231
C+C GY + G +C +G+ C G C G E C
Sbjct: 2107 FRCECPFGYSLDFTGINCVDTDECSVGH----------PCGQ--GTCTNVIGGFECACAD 2154
Query: 232 CKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKK 291
+ + + C DIDEC C C NTEGSY C
Sbjct: 2155 GFEPGLM--MTCEDIDECSLNPLLCAFR--CHNTEGSYLCT------------------- 2191
Query: 292 CSPGY--QQVGSKCLDVDECET--EVCPGENKQCENTEGGYRCICAEGYKQMEG 341
C GY ++ G+ C DVDEC + C +C+N G + C+C G + + G
Sbjct: 2192 CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPG 2245
Score = 61.2 bits (147), Expect = 2e-09
Identities = 57/204 (27%), Positives = 74/204 (36%), Gaps = 54/204 (26%)
Query: 152 CLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGY----GGEACGQCGLGYFEAERNAS 207
C PG PCG +G C GS C+C G+ G C E +
Sbjct: 2489 CSAQPG----PCGAHGHCHNTP---GSFRCECHQGFTLVSSGHGCEDVN------ECDGP 2535
Query: 208 HLVCSACFGPCA--RCSGPEESNCLQCKKGWALHH--LKCVDIDECGTEGANCGADQFCV 263
H C RCS C +G+ H +CVD +EC CG+ C
Sbjct: 2536 HRCQHGCQNQLGGYRCS---------CPQGFTQHSQWAQCVDENECALSPPTCGSAS-CR 2585
Query: 264 NTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQ--QVGSKCLDVDECETEVCPGENKQC 321
NT G + C C G+ Q C +VDEC P + C
Sbjct: 2586 NTLGGFRC-------------------VCPSGFDFDQALGGCQEVDECAGRRGPC-SYSC 2625
Query: 322 ENTEGGYRCICAEGY-KQMEGICV 344
NT GG+ C C +GY + +G CV
Sbjct: 2626 ANTPGGFLCGCPQGYFRAGQGHCV 2649
Score = 58.5 bits (140), Expect = 1e-08
Identities = 74/278 (26%), Positives = 97/278 (34%), Gaps = 102/278 (36%)
Query: 152 CLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGG----EAC----------GQCGL 197
C+ T PC +G C G+ HC C G+ +AC G C L
Sbjct: 447 CIDVDECTSSPCH-HGDCVNIP---GTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHL 502
Query: 198 GYFEAERNASHLVCSACF------------GPCAR--------CSGPEESNCLQCKKGWA 237
G + VC+A F CA C + S CK G+
Sbjct: 503 GRCVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNEDGSFSCLCKPGFL 562
Query: 238 L----HHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLG------------- 280
L H+ C+DIDEC T G C + C NTEGS+ C+ +G
Sbjct: 563 LAPGGHY--CMDIDECQTPGI-C-VNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRS 618
Query: 281 -CMGA-GPGRCKKCSPG------------------------------YQQVGSKCL---- 304
C GA G C + PG +Q + S L
Sbjct: 619 TCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITT 678
Query: 305 ---DVDEC--ETEVCPGENKQCENTEGGYRCICAEGYK 337
D++EC + EVC N CEN G YRC+C GY+
Sbjct: 679 DGRDINECALDPEVCA--NGVCENLRGSYRCVCNLGYE 714
Score = 57.4 bits (137), Expect = 2e-08
Identities = 73/253 (28%), Positives = 92/253 (36%), Gaps = 67/253 (26%)
Query: 131 FQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGE 190
FQ LCS L + T G C E C G CE GS C C GY
Sbjct: 666 FQALCSSGLGIT----TDGRDINECALDPE-VCAN-GVCEN---LRGSYRCVCNLGYEAG 716
Query: 191 ACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECG 250
A G+ E N+ L+C G C G +C W + C D+DEC
Sbjct: 717 ASGKDCTDVDECALNS--LLCDN--GWCQNSPGSYSCSCPPGFHFWQDTEI-CKDVDECL 771
Query: 251 TEGANCGADQFCVNTEGSYECR---------------DCAKA------------------ 277
+ G C N GSY C+ D K
Sbjct: 772 SSPCVSGV---CRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGA 828
Query: 278 -----CLGCMGAGPG----RCK---KCSPGYQQV-GSKCLDVDECET--EVCPGENKQCE 322
C +GA G RC+ C+ G+ ++ G C DV+ECE+ VCP N +C
Sbjct: 829 SLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCDDVNECESFPGVCP--NGRCV 886
Query: 323 NTEGGYRCICAEG 335
NT G +RC C EG
Sbjct: 887 NTAGSFRCECPEG 899
Score = 55.8 bits (133), Expect = 7e-08
Identities = 63/235 (26%), Positives = 75/235 (31%), Gaps = 48/235 (20%)
Query: 135 CSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQ 194
CS C GT PSC G R G C GT G+ C CQ GY G CGQ
Sbjct: 95 CSQPNLCTCADGTLAPSC-----GVSRGSGCSVSCMNGGTCRGAS-CLCQKGYTGTVCGQ 148
Query: 195 --CGLGYFEAERNASHLVCSACFG-------------PCARCSGPEESNCLQCKKGWALH 239
C G R C+ +G PC GPE C G
Sbjct: 149 PICDRGCHNGGRCIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPE--GCQHQLTG---- 202
Query: 240 HLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQV 299
L C C T G G C C A P C++
Sbjct: 203 -LVCTKALCCATVGRAWGLP-----------CELCP--------AQPHPCRRGFIPNIHT 242
Query: 300 GSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGF 354
G+ C DVDEC+ + C N G + C C G++ + E A F
Sbjct: 243 GA-CQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/148 (31%), Positives = 58/148 (39%), Gaps = 29/148 (19%)
Query: 211 CSACFGPCAR--CSGPEESNCLQCKKGWALHH--LKCVDIDECGTEGANCGADQFCVNTE 266
C+ G C C + S +C G++L + CVD DEC G CG C N
Sbjct: 2088 CAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSV-GHPCGQGT-CTNVI 2145
Query: 267 GSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETE--VCPGENKQCENT 324
G +EC CA G PG C D+DEC +C +C NT
Sbjct: 2146 GGFECA-CAD------GFEPGLMMTCE-----------DIDECSLNPLLCAF---RCHNT 2184
Query: 325 EGGYRCICAEGYKQMEGICVKEQIPESA 352
EG Y C C GY E + + E A
Sbjct: 2185 EGSYLCTCPAGYTLREDGAMCRDVDECA 2212
Score = 52.4 bits (124), Expect = 8e-07
Identities = 59/224 (26%), Positives = 74/224 (33%), Gaps = 60/224 (26%)
Query: 151 SCLPCPGGTERPCGGY----GQCEGEG--------TRGGSGHCDCQAG------------ 186
SCL PG P G Y +C+ G GS C C G
Sbjct: 554 SCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVD 613
Query: 187 -------YGGEACGQCGLGYFEAERNASHLVCSAC---FG-PCARCSGPEESNCLQ-CKK 234
YG G C F S C+ FG PC C + + C
Sbjct: 614 THVRSTCYGAIEKGSCARP-FPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSS 672
Query: 235 GWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSP 294
G + DI+EC + C A+ C N GSY C C+
Sbjct: 673 GLGIT-TDGRDINECALDPEVC-ANGVCENLRGSYRC-------------------VCNL 711
Query: 295 GYQQ--VGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGY 336
GY+ G C DVDEC +N C+N+ G Y C C G+
Sbjct: 712 GYEAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGF 755
Score = 44.7 bits (104), Expect = 2e-04
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 5/70 (7%)
Query: 271 CRDCAKACLG--CMGAGPGRCKKCSPGY-QQVGSKCLDVDECETEVCPGENKQCENTEGG 327
CR CL C+ +C+ GY Q V +C+DVDEC + C + C N G
Sbjct: 412 CRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECIDVDECTSSPC--HHGDCVNIPGT 469
Query: 328 YRCICAEGYK 337
Y C C G++
Sbjct: 470 YHCRCYPGFQ 479
Score = 44.7 bits (104), Expect = 2e-04
Identities = 70/309 (22%), Positives = 95/309 (30%), Gaps = 90/309 (29%)
Query: 120 WFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPC------GGYGQCEGEG 173
W E DL + C C P G CL PG C G+ + +
Sbjct: 1312 WVGDGFECHDLDE--CVSQEHRCSPRG----DCLNVPGSYRCTCRQGFAGDGFFCEDRDE 1365
Query: 174 TRGGSGHCD---CQAGYGGEACGQCGLGYFEAERNASHLVCSAC-------FGPCARCSG 223
CD C GG C +C +G+ E + + C FG C G
Sbjct: 1366 CAENVDLCDNGQCLNAPGGYRC-ECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPG 1424
Query: 224 PEESNCLQCKKGWALHHL--KCVDIDECGTEGANCGADQFCVNTEGSYECR--------- 272
C+ C G+ L C DI+EC + NC + C+NT GSY C
Sbjct: 1425 M--FRCI-CNGGYELDRGGGNCTDINECA-DPVNC-INGVCINTPGSYLCSCPQDFELNP 1479
Query: 273 ---------------------DCAKACLGCMGAGPGRCKKCSPGYQQVGSKCL------- 304
D +C +G G R C + G+ C
Sbjct: 1480 SGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANT 1539
Query: 305 -----------------------DVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEG 341
D+DEC+ + C NT G ++C C GY E
Sbjct: 1540 TEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEH 1599
Query: 342 ICVKEQIPE 350
+ E I E
Sbjct: 1600 TRICEDIDE 1608
Score = 40.8 bits (94), Expect = 0.002
Identities = 45/179 (25%), Positives = 56/179 (31%), Gaps = 60/179 (33%)
Query: 231 QCKKGWAL--HHLKCVDIDECGTEGANCGADQFCVNTEGSYEC------------RDCA- 275
+C G+ L H C DIDEC T CG C NT G+Y C +C
Sbjct: 1589 ECPPGYHLSEHTRICEDIDECSTHSGICGPGT-CYNTLGNYTCVCPAEYLQVNGGNNCMD 1647
Query: 276 ------------------------KACLGCMGAGPG---RCKKC----SPGYQQV----- 299
K C G C+ C SP YQ +
Sbjct: 1648 MRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQA 1707
Query: 300 --------GSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPE 350
K LD+DEC N C N G +RC C G+ + E + E
Sbjct: 1708 PGFLTDIHTGKPLDIDECGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDE 1766
Score = 31.2 bits (69), Expect = 1.8
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 7/56 (12%)
Query: 294 PGYQQVGSKCLD--VDECE--TEVCPGENKQCENTEGGYRCICAEGYKQ-MEGICV 344
PG +G+ L+ +D C T +C N +C T YRC C GY Q + G C+
Sbjct: 395 PGNSNIGTATLNQTIDICRHFTNLCL--NGRCLPTPSSYRCECNVGYTQDVRGECI 448
>gi|51873055 fibulin 2 isoform b precursor [Homo sapiens]
Length = 1184
Score = 79.7 bits (195), Expect = 5e-15
Identities = 64/230 (27%), Positives = 89/230 (38%), Gaps = 54/230 (23%)
Query: 153 LPCPGGTERPCGGYGQCEGE-GTRGGSGHCDCQAGYG----GEAC---GQCGLGYFEAER 204
+P P C G C+ T GGS C C GY G +C +C R
Sbjct: 673 IPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSR 732
Query: 205 NASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVN 264
H V + C + L C+ G+AL +C D+DEC C C N
Sbjct: 733 G-EHCVNTLGSFHCYKA--------LTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQN 783
Query: 265 TEGSYECRDCAKACLGCMGAGPGRC----------KKCSPGYQQV--------------- 299
T+GS+ C+ + G + G C + C PG+ +
Sbjct: 784 TKGSFYCQARQRCMDGFLQDPEGNCVDINECTSLSEPCRPGFSCINTVGSYTCQRNPLIC 843
Query: 300 ---------GSKCLDVDECETEV--CPGENKQCENTEGGYRCICAEGYKQ 338
G+KC+DV+ECET V C GE + C N G YRC C G+++
Sbjct: 844 ARGYHASDDGTKCVDVNECETGVHRC-GEGQVCHNLPGSYRCDCKAGFQR 892
Score = 71.2 bits (173), Expect = 2e-12
Identities = 48/143 (33%), Positives = 66/143 (46%), Gaps = 32/143 (22%)
Query: 226 ESNCLQCKKGWALHH--LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACL---- 279
+ N L C +G+ KCVD++EC T CG Q C N GSY C DC
Sbjct: 837 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRC-DCKAGFQRDAF 895
Query: 280 --GCMG-----AGPGR-----CKK--------CSPGYQQV--GSKCLDVDECETEVCPGE 317
GC+ A PGR C+ C+ G+ G +C DV+ECE + C
Sbjct: 896 GRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC--- 952
Query: 318 NKQCENTEGGYRCICAEGYKQME 340
+++C N G Y+C C +GY+ E
Sbjct: 953 SQECANIYGSYQCYCRQGYQLAE 975
Score = 59.7 bits (143), Expect = 5e-09
Identities = 56/189 (29%), Positives = 71/189 (37%), Gaps = 43/189 (22%)
Query: 155 CPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSAC 214
C G R CG C GS CDC+AG+ +A G+ + E + L C
Sbjct: 862 CETGVHR-CGEGQVCHN---LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC 917
Query: 215 FGPCA--RCSGPEESNCLQCKKGW--ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYE 270
RCS C G+ A +C D++EC E C Q C N GSY+
Sbjct: 918 ENTLGSYRCS---------CASGFLLAADGKRCEDVNEC--EAQRC--SQECANIYGSYQ 964
Query: 271 CRDCAKACLGCMGAGPGRCKKCSPGYQ--QVGSKCLDVDECETEVCPGENKQCENTEGGY 328
C C GYQ + G C D+DEC +C N G Y
Sbjct: 965 C-------------------YCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1005
Query: 329 RCICAE-GY 336
+C C E GY
Sbjct: 1006 QCACPEQGY 1014
Score = 43.1 bits (100), Expect = 5e-04
Identities = 36/148 (24%), Positives = 51/148 (34%), Gaps = 26/148 (17%)
Query: 177 GSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGW 236
GS C C+ GY G E + A L C C G + C +
Sbjct: 961 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGIL----CTFRCLNVPGSYQCACPEQGYTM 1016
Query: 237 ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGY 296
+ C D+DEC NC + C N +GS+ C +C P Y
Sbjct: 1017 TANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRF----------------ECPPNY 1060
Query: 297 QQVGSKCLDVDECETEVCPGENKQCENT 324
QV +CE C + +C+N+
Sbjct: 1061 VQVSK-----TKCERTTC-HDFLECQNS 1082
Score = 29.3 bits (64), Expect = 7.0
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 12/66 (18%)
Query: 305 DVDECETEVCPGENKQ--CENTEGGYRCICAEGYK--------QMEGICVKEQIPESAGF 354
D DEC + PGE Q C NT G Y C C G+ + EG + + P+
Sbjct: 604 DQDECL--LLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
Query: 355 FSEMTE 360
SE ++
Sbjct: 662 KSEFSQ 667
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 79.3 bits (194), Expect = 6e-15
Identities = 67/211 (31%), Positives = 89/211 (42%), Gaps = 46/211 (21%)
Query: 153 LPCPGGTERPCGGYGQCEGE-GTRGGSGHCDCQAGYG----GEAC---GQCGLGYFEAER 204
+P P C G C+ T GGS C C GY G +C +C +G + R
Sbjct: 673 IPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSR 732
Query: 205 NASHLVCSACFGP--CARCSGPEESNCLQCKKGWALH-HLKCVDIDECGTEGANCGADQF 261
C G C ++ + C G+ L+ H KCVDI+EC T+ C +
Sbjct: 733 RQ---FCVNTLGSFYCV-------NHTVLCADGYILNAHRKCVDINECVTDLHTCSRGEH 782
Query: 262 CVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECE--TEVC-PGEN 318
CVNT GS+ C + C PGY +C DVDEC T C PG
Sbjct: 783 CVNTLGSFHCY---------------KALTCEPGYALKDGECEDVDECAMGTHTCQPG-- 825
Query: 319 KQCENTEGGYRC----ICAEGYKQ-MEGICV 344
C+NT+G + C C +G+ Q EG CV
Sbjct: 826 FLCQNTKGSFYCQARQRCMDGFLQDPEGNCV 856
Score = 71.2 bits (173), Expect = 2e-12
Identities = 48/143 (33%), Positives = 66/143 (46%), Gaps = 32/143 (22%)
Query: 226 ESNCLQCKKGWALHH--LKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACL---- 279
+ N L C +G+ KCVD++EC T CG Q C N GSY C DC
Sbjct: 884 QRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRC-DCKAGFQRDAF 942
Query: 280 --GCMG-----AGPGR-----CKK--------CSPGYQQV--GSKCLDVDECETEVCPGE 317
GC+ A PGR C+ C+ G+ G +C DV+ECE + C
Sbjct: 943 GRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRC--- 999
Query: 318 NKQCENTEGGYRCICAEGYKQME 340
+++C N G Y+C C +GY+ E
Sbjct: 1000 SQECANIYGSYQCYCRQGYQLAE 1022
Score = 59.7 bits (143), Expect = 5e-09
Identities = 56/189 (29%), Positives = 71/189 (37%), Gaps = 43/189 (22%)
Query: 155 CPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSAC 214
C G R CG C GS CDC+AG+ +A G+ + E + L C
Sbjct: 909 CETGVHR-CGEGQVCHN---LPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC 964
Query: 215 FGPCA--RCSGPEESNCLQCKKGW--ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYE 270
RCS C G+ A +C D++EC E C Q C N GSY+
Sbjct: 965 ENTLGSYRCS---------CASGFLLAADGKRCEDVNEC--EAQRC--SQECANIYGSYQ 1011
Query: 271 CRDCAKACLGCMGAGPGRCKKCSPGYQ--QVGSKCLDVDECETEVCPGENKQCENTEGGY 328
C C GYQ + G C D+DEC +C N G Y
Sbjct: 1012 C-------------------YCRQGYQLAEDGHTCTDIDECAQGAGILCTFRCLNVPGSY 1052
Query: 329 RCICAE-GY 336
+C C E GY
Sbjct: 1053 QCACPEQGY 1061
Score = 43.1 bits (100), Expect = 5e-04
Identities = 36/148 (24%), Positives = 51/148 (34%), Gaps = 26/148 (17%)
Query: 177 GSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGW 236
GS C C+ GY G E + A L C C G + C +
Sbjct: 1008 GSYQCYCRQGYQLAEDGHTCTDIDECAQGAGIL----CTFRCLNVPGSYQCACPEQGYTM 1063
Query: 237 ALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGY 296
+ C D+DEC NC + C N +GS+ C +C P Y
Sbjct: 1064 TANGRSCKDVDECALGTHNCSEAETCHNIQGSFRCLRF----------------ECPPNY 1107
Query: 297 QQVGSKCLDVDECETEVCPGENKQCENT 324
QV +CE C + +C+N+
Sbjct: 1108 VQVSK-----TKCERTTC-HDFLECQNS 1129
Score = 29.3 bits (64), Expect = 7.0
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 12/66 (18%)
Query: 305 DVDECETEVCPGENKQ--CENTEGGYRCICAEGYK--------QMEGICVKEQIPESAGF 354
D DEC + PGE Q C NT G Y C C G+ + EG + + P+
Sbjct: 604 DQDECL--LLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPAL 661
Query: 355 FSEMTE 360
SE ++
Sbjct: 662 KSEFSQ 667
>gi|86788132 EGF-containing fibulin-like extracellular matrix
protein 1 precursor [Homo sapiens]
Length = 493
Score = 78.6 bits (192), Expect = 1e-14
Identities = 40/112 (35%), Positives = 58/112 (51%), Gaps = 22/112 (19%)
Query: 227 SNCLQCKKGWAL-HHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAG 285
S+ +QC G+ H C DIDEC NC ADQ C+N GS+ C
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFAC-------------- 199
Query: 286 PGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
+C PGYQ+ G +C+D+DEC + P +++C NT G + C C+ G++
Sbjct: 200 -----QCPPGYQKRGEQCVDIDEC--TIPPYCHQRCVNTPGSFYCQCSPGFQ 244
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/177 (29%), Positives = 74/177 (41%), Gaps = 42/177 (23%)
Query: 194 QCGLGYFEAERNASHLV--CSACFGPCAR---CSGPEESNCLQCKKGWALHHLKCVDIDE 248
QC GY ++E N + C+A C C S QC G+ +CVDIDE
Sbjct: 158 QCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDE 217
Query: 249 CGTEGANCGADQFCVNTEGSYECR------------------------DCAKACLGCMGA 284
C T C Q CVNT GS+ C+ CA+ C +G+
Sbjct: 218 C-TIPPYC--HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGS 274
Query: 285 GPGRCKKCSPGYQQVGSK--CLDVDECETE--VCPGENKQCENTEGGYRCICAEGYK 337
+C+ GY+ + C D+DEC T +C QC N G + C+C +GY+
Sbjct: 275 F---ICQCNQGYELSSDRLNCEDIDECRTSSYLC---QYQCVNEPGKFSCMCPQGYQ 325
Score = 62.8 bits (151), Expect = 6e-10
Identities = 58/191 (30%), Positives = 74/191 (38%), Gaps = 32/191 (16%)
Query: 146 GTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERN 205
G+F C P C +C T H C G C QC G+ A N
Sbjct: 195 GSFACQCPPGYQKRGEQCVDIDEC----TIPPYCHQRCVNTPGSFYC-QCSPGFQLAANN 249
Query: 206 ASHLVCSAC--FGPCAR-CSGPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCGADQ 260
+ + + C CA+ C S QC +G+ L L C DIDEC T C
Sbjct: 250 YTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ- 308
Query: 261 FCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSK-CLDVDECETEVCPGENK 319
CVN G + C C GYQ V S+ C D++ECET E++
Sbjct: 309 -CVNEPGKFSCM-------------------CPQGYQVVRSRTCQDINECETTNECREDE 348
Query: 320 QCENTEGGYRC 330
C N GG+RC
Sbjct: 349 MCWNYHGGFRC 359
Score = 38.1 bits (87), Expect = 0.015
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query: 284 AGPGRCKKCSPGYQQVGSK-CLDVDECE--TEVCPGENKQCENTEGGYRCICAEGYKQME 340
+ P +C+ GY+Q C D+DEC T C + + C N G + C C GY++
Sbjct: 151 SNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRAD-QVCINLRGSFACQCPPGYQKRG 209
Query: 341 GICV 344
CV
Sbjct: 210 EQCV 213
Score = 35.4 bits (80), Expect = 0.098
Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 5/45 (11%)
Query: 291 KCSPGYQ--QVGSKCLDVDECE--TEVCPGENKQCENTEGGYRCI 331
+C+ GY+ V +C D+DEC+ + C G K C N GGY C+
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK-CVNHYGGYLCL 71
Score = 32.0 bits (71), Expect = 1.1
Identities = 17/43 (39%), Positives = 18/43 (41%), Gaps = 2/43 (4%)
Query: 231 QCKKG--WALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
QC G W +C DIDEC C CVN G Y C
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>gi|86788015 EGF-containing fibulin-like extracellular matrix
protein 1 precursor [Homo sapiens]
Length = 493
Score = 78.6 bits (192), Expect = 1e-14
Identities = 40/112 (35%), Positives = 58/112 (51%), Gaps = 22/112 (19%)
Query: 227 SNCLQCKKGWAL-HHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAG 285
S+ +QC G+ H C DIDEC NC ADQ C+N GS+ C
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFAC-------------- 199
Query: 286 PGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
+C PGYQ+ G +C+D+DEC + P +++C NT G + C C+ G++
Sbjct: 200 -----QCPPGYQKRGEQCVDIDEC--TIPPYCHQRCVNTPGSFYCQCSPGFQ 244
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/177 (29%), Positives = 74/177 (41%), Gaps = 42/177 (23%)
Query: 194 QCGLGYFEAERNASHLV--CSACFGPCAR---CSGPEESNCLQCKKGWALHHLKCVDIDE 248
QC GY ++E N + C+A C C S QC G+ +CVDIDE
Sbjct: 158 QCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDE 217
Query: 249 CGTEGANCGADQFCVNTEGSYECR------------------------DCAKACLGCMGA 284
C T C Q CVNT GS+ C+ CA+ C +G+
Sbjct: 218 C-TIPPYC--HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGS 274
Query: 285 GPGRCKKCSPGYQQVGSK--CLDVDECETE--VCPGENKQCENTEGGYRCICAEGYK 337
+C+ GY+ + C D+DEC T +C QC N G + C+C +GY+
Sbjct: 275 F---ICQCNQGYELSSDRLNCEDIDECRTSSYLC---QYQCVNEPGKFSCMCPQGYQ 325
Score = 62.8 bits (151), Expect = 6e-10
Identities = 58/191 (30%), Positives = 74/191 (38%), Gaps = 32/191 (16%)
Query: 146 GTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERN 205
G+F C P C +C T H C G C QC G+ A N
Sbjct: 195 GSFACQCPPGYQKRGEQCVDIDEC----TIPPYCHQRCVNTPGSFYC-QCSPGFQLAANN 249
Query: 206 ASHLVCSAC--FGPCAR-CSGPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCGADQ 260
+ + + C CA+ C S QC +G+ L L C DIDEC T C
Sbjct: 250 YTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ- 308
Query: 261 FCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSK-CLDVDECETEVCPGENK 319
CVN G + C C GYQ V S+ C D++ECET E++
Sbjct: 309 -CVNEPGKFSCM-------------------CPQGYQVVRSRTCQDINECETTNECREDE 348
Query: 320 QCENTEGGYRC 330
C N GG+RC
Sbjct: 349 MCWNYHGGFRC 359
Score = 38.1 bits (87), Expect = 0.015
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query: 284 AGPGRCKKCSPGYQQVGSK-CLDVDECE--TEVCPGENKQCENTEGGYRCICAEGYKQME 340
+ P +C+ GY+Q C D+DEC T C + + C N G + C C GY++
Sbjct: 151 SNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRAD-QVCINLRGSFACQCPPGYQKRG 209
Query: 341 GICV 344
CV
Sbjct: 210 EQCV 213
Score = 35.4 bits (80), Expect = 0.098
Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 5/45 (11%)
Query: 291 KCSPGYQ--QVGSKCLDVDECE--TEVCPGENKQCENTEGGYRCI 331
+C+ GY+ V +C D+DEC+ + C G K C N GGY C+
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK-CVNHYGGYLCL 71
Score = 32.0 bits (71), Expect = 1.1
Identities = 17/43 (39%), Positives = 18/43 (41%), Gaps = 2/43 (4%)
Query: 231 QCKKG--WALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
QC G W +C DIDEC C CVN G Y C
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>gi|9665262 EGF-containing fibulin-like extracellular matrix protein
1 precursor [Homo sapiens]
Length = 493
Score = 78.6 bits (192), Expect = 1e-14
Identities = 40/112 (35%), Positives = 58/112 (51%), Gaps = 22/112 (19%)
Query: 227 SNCLQCKKGWAL-HHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAG 285
S+ +QC G+ H C DIDEC NC ADQ C+N GS+ C
Sbjct: 154 SHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFAC-------------- 199
Query: 286 PGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
+C PGYQ+ G +C+D+DEC + P +++C NT G + C C+ G++
Sbjct: 200 -----QCPPGYQKRGEQCVDIDEC--TIPPYCHQRCVNTPGSFYCQCSPGFQ 244
Score = 67.8 bits (164), Expect = 2e-11
Identities = 53/177 (29%), Positives = 74/177 (41%), Gaps = 42/177 (23%)
Query: 194 QCGLGYFEAERNASHLV--CSACFGPCAR---CSGPEESNCLQCKKGWALHHLKCVDIDE 248
QC GY ++E N + C+A C C S QC G+ +CVDIDE
Sbjct: 158 QCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDE 217
Query: 249 CGTEGANCGADQFCVNTEGSYECR------------------------DCAKACLGCMGA 284
C T C Q CVNT GS+ C+ CA+ C +G+
Sbjct: 218 C-TIPPYC--HQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGS 274
Query: 285 GPGRCKKCSPGYQQVGSK--CLDVDECETE--VCPGENKQCENTEGGYRCICAEGYK 337
+C+ GY+ + C D+DEC T +C QC N G + C+C +GY+
Sbjct: 275 F---ICQCNQGYELSSDRLNCEDIDECRTSSYLC---QYQCVNEPGKFSCMCPQGYQ 325
Score = 62.8 bits (151), Expect = 6e-10
Identities = 58/191 (30%), Positives = 74/191 (38%), Gaps = 32/191 (16%)
Query: 146 GTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERN 205
G+F C P C +C T H C G C QC G+ A N
Sbjct: 195 GSFACQCPPGYQKRGEQCVDIDEC----TIPPYCHQRCVNTPGSFYC-QCSPGFQLAANN 249
Query: 206 ASHLVCSAC--FGPCAR-CSGPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCGADQ 260
+ + + C CA+ C S QC +G+ L L C DIDEC T C
Sbjct: 250 YTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQ- 308
Query: 261 FCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSK-CLDVDECETEVCPGENK 319
CVN G + C C GYQ V S+ C D++ECET E++
Sbjct: 309 -CVNEPGKFSCM-------------------CPQGYQVVRSRTCQDINECETTNECREDE 348
Query: 320 QCENTEGGYRC 330
C N GG+RC
Sbjct: 349 MCWNYHGGFRC 359
Score = 38.1 bits (87), Expect = 0.015
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query: 284 AGPGRCKKCSPGYQQVGSK-CLDVDECE--TEVCPGENKQCENTEGGYRCICAEGYKQME 340
+ P +C+ GY+Q C D+DEC T C + + C N G + C C GY++
Sbjct: 151 SNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRAD-QVCINLRGSFACQCPPGYQKRG 209
Query: 341 GICV 344
CV
Sbjct: 210 EQCV 213
Score = 35.4 bits (80), Expect = 0.098
Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 5/45 (11%)
Query: 291 KCSPGYQ--QVGSKCLDVDECE--TEVCPGENKQCENTEGGYRCI 331
+C+ GY+ V +C D+DEC+ + C G K C N GGY C+
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMK-CVNHYGGYLCL 71
Score = 32.0 bits (71), Expect = 1.1
Identities = 17/43 (39%), Positives = 18/43 (41%), Gaps = 2/43 (4%)
Query: 231 QCKKG--WALHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
QC G W +C DIDEC C CVN G Y C
Sbjct: 28 QCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLC 70
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 78.2 bits (191), Expect = 1e-14
Identities = 55/164 (33%), Positives = 68/164 (41%), Gaps = 36/164 (21%)
Query: 213 ACFGPCAR-CSGPEESNCLQCKKGW--ALHHLKCVDIDECGTEGANCGADQFCVNTEGSY 269
A PC+ C + C KG A C DIDEC C A Q C NT GSY
Sbjct: 5112 AAGNPCSHSCHNAMGTYYCSCPKGLTIAADGRTCQDIDECALGRHTCHAGQDCDNTIGSY 5171
Query: 270 EC--------------------------RDCAKACLGCMGAGPGRCKKCSPGYQQVGSKC 303
C C + C +G+ C C PGYQ G KC
Sbjct: 5172 RCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSF--HCG-CEPGYQLKGRKC 5228
Query: 304 LDVDECETEVCPGENKQCENTEGGYRCI--CAEGYKQME-GICV 344
+DV+EC VC ++ C+NT GGY+CI C G + E G C+
Sbjct: 5229 MDVNECRQNVC-RPDQHCKNTRGGYKCIDLCPNGMTKAENGTCI 5271
Score = 77.8 bits (190), Expect = 2e-14
Identities = 54/162 (33%), Positives = 69/162 (42%), Gaps = 25/162 (15%)
Query: 182 DCQAGYGGEACG-QCGLGYFEAERNASHLVCSAC--FGPC-ARCSGPEESNCLQCKKGWA 237
DC G C +CG G+ S + C PC RC S C+ G+
Sbjct: 5163 DCDNTIGSYRCVVRCGSGFRRTSDGLSCQDINECQESSPCHQRCFNAIGSFHCGCEPGYQ 5222
Query: 238 LHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQ 297
L KC+D++EC C DQ C NT G Y+C D P K G
Sbjct: 5223 LKGRKCMDVNECRQNV--CRPDQHCKNTRGGYKCIDLC----------PNGMTKAENG-- 5268
Query: 298 QVGSKCLDVDECE--TEVCPGENKQCENTEGGYRCICAEGYK 337
C+D+DEC+ T C N+ CENT G YRC+C GY+
Sbjct: 5269 ----TCIDIDECKDGTHQCR-YNQICENTRGSYRCVCPRGYR 5305
Score = 71.2 bits (173), Expect = 2e-12
Identities = 53/164 (32%), Positives = 68/164 (41%), Gaps = 35/164 (21%)
Query: 177 GSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEES-NCLQ-CKK 234
GS HC C+ GY + G+ + E +N VC P C C+ C
Sbjct: 5211 GSFHCGCEPGY--QLKGRKCMDVNECRQN----VCR----PDQHCKNTRGGYKCIDLCPN 5260
Query: 235 GWA-LHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCS 293
G + C+DIDEC C +Q C NT GSY C C
Sbjct: 5261 GMTKAENGTCIDIDECKDGTHQCRYNQICENTRGSYRC-------------------VCP 5301
Query: 294 PGY--QQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEG 335
GY Q VG C+D++ECE P + QC NT G ++CIC G
Sbjct: 5302 RGYRSQGVGRPCMDINECEQVPKPCAH-QCSNTPGSFKCICPPG 5344
Score = 66.2 bits (160), Expect = 5e-11
Identities = 45/126 (35%), Positives = 54/126 (42%), Gaps = 30/126 (23%)
Query: 232 CKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKK 291
C +G H CVDIDEC A C NT GSY+C
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDA---CQHECKNTFGSYQC-------------------I 5456
Query: 292 CSPGYQQV--GSKCLDVDEC-ETEVCPGENKQCENTEGGYRCI---CAEGYKQ--MEGIC 343
C PGYQ G C D+DEC E V G N+ C N G Y+CI C Y++ + G C
Sbjct: 5457 CPPGYQLTHNGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGFC 5516
Query: 344 VKEQIP 349
+K P
Sbjct: 5517 LKNCPP 5522
Score = 48.1 bits (113), Expect = 1e-05
Identities = 22/49 (44%), Positives = 29/49 (59%), Gaps = 4/49 (8%)
Query: 290 KKCSPGYQQVGSKCLDVDECE-TEVCPGENKQCENTEGGYRCICAEGYK 337
K C G + C+D+DECE T+ C E C+NT G Y+CIC GY+
Sbjct: 5417 KTCPEGSEASHDTCVDIDECENTDACQHE---CKNTFGSYQCICPPGYQ 5462
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/129 (29%), Positives = 50/129 (38%), Gaps = 39/129 (30%)
Query: 206 ASHLVC---------SACFGPCARCSGPEESNCLQCKKGWALHH--LKCVDIDECGTEGA 254
ASH C AC C G + C+ C G+ L H C DIDEC +
Sbjct: 5425 ASHDTCVDIDECENTDACQHECKNTFGSYQ--CI-CPPGYQLTHNGKTCQDIDECLEQNV 5481
Query: 255 NCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQ--VGSKCLDVDECETE 312
+CG ++ C N GSY+C D C P YQ+ V CL +
Sbjct: 5482 HCGPNRMCFNMRGSYQCID----------------TPCPPNYQRDPVSGFCL-------K 5518
Query: 313 VCPGENKQC 321
CP + +C
Sbjct: 5519 NCPPNDLEC 5527
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 76.3 bits (186), Expect = 5e-14
Identities = 48/161 (29%), Positives = 67/161 (41%), Gaps = 29/161 (18%)
Query: 217 PCARCSGPEESNCLQCKKGWALHHL-KCVDIDECGTEGANCGADQFCVNTEGSYECRDCA 275
P + + P S L C+ G+ + +CVD+DEC T+ C Q C+NTEG Y C
Sbjct: 98 PLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICINTEGGYTC---- 153
Query: 276 KACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEG 335
C+ GY + +CLD+DEC C + C N G Y C C G
Sbjct: 154 ---------------SCTDGYWLLEGQCLDIDECRYGYC---QQLCANVPGSYSCTCNPG 195
Query: 336 YKQMEGICVKEQIPESAGFFSEMTEDELVVLQQMFFGIIIC 376
+ E + + E A TE+ V +G IC
Sbjct: 196 FTLNEDGRSCQDVNECA------TENPCVQTCVNTYGSFIC 230
Score = 68.9 bits (167), Expect = 8e-12
Identities = 49/142 (34%), Positives = 60/142 (42%), Gaps = 28/142 (19%)
Query: 231 QCKKGWALHHL--KCVDIDECGTEGANCGADQFCVNTEGSYEC--------RDCAKACLG 280
QC G+ L +C+DIDEC T C D CVN G Y C R
Sbjct: 26 QCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLCIPRTNPVYRGPYSNPYS 85
Query: 281 CMGAGP----------------GRCKKCSPGYQ-QVGSKCLDVDECETEVCPGENKQ-CE 322
+GP R C GYQ ++C+DVDEC T+ Q C
Sbjct: 86 TPYSGPYPAAAPPLSAPNYPTISRPLICRFGYQMDESNQCVDVDECATDSHQCNPTQICI 145
Query: 323 NTEGGYRCICAEGYKQMEGICV 344
NTEGGY C C +GY +EG C+
Sbjct: 146 NTEGGYTCSCTDGYWLLEGQCL 167
Score = 52.4 bits (124), Expect = 8e-07
Identities = 56/211 (26%), Positives = 77/211 (36%), Gaps = 56/211 (26%)
Query: 152 CLPCPGGTERPC-GGYGQCEGEGTRGGSGHC----DCQAGYGGEACGQ--------CGLG 198
C+ GG C GY EG+ C +C+ GY + C C G
Sbjct: 144 CINTEGGYTCSCTDGYWLLEGQ--------CLDIDECRYGYCQQLCANVPGSYSCTCNPG 195
Query: 199 YFEAERNASHLVCSACF--GPCAR-CSGPEESNCLQCKKGWALHH--LKCVDIDECGTEG 253
+ E S + C PC + C S +C G+ L + C D+DEC
Sbjct: 196 FTLNEDGRSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCSDMDECSFSE 255
Query: 254 ANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSK--CLDVDECE- 310
C + CVN G+Y C C PGY + C D++ECE
Sbjct: 256 FLCQHE--CVNQPGTYFC-------------------SCPPGYILLDDNRSCQDINECEH 294
Query: 311 -TEVCPGENKQCENTEGGYRCI----CAEGY 336
C + C N +GG++CI C E Y
Sbjct: 295 RNHTC-NLQQTCYNLQGGFKCIDPIRCEEPY 324
Score = 42.7 bits (99), Expect = 6e-04
Identities = 48/184 (26%), Positives = 66/184 (35%), Gaps = 40/184 (21%)
Query: 151 SCLPCPGGT----ERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNA 206
SC PG T R C +C E + C YG C +C GY E E +
Sbjct: 189 SCTCNPGFTLNEDGRSCQDVNECATENPCVQT----CVNTYGSFIC-RCDPGY-ELEEDG 242
Query: 207 SHLV----CSACFGPCAR-CSGPEESNCLQCKKGWAL--HHLKCVDIDECGTEGANCGAD 259
H CS C C + C G+ L + C DI+EC C
Sbjct: 243 VHCSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSCQDINECEHRNHTCNLQ 302
Query: 260 QFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENK 319
Q C N +G ++C D P RC++ P + ++C+ CP EN
Sbjct: 303 QTCYNLQGGFKCID------------PIRCEE--PYLRISDNRCM---------CPAENP 339
Query: 320 QCEN 323
C +
Sbjct: 340 GCRD 343
Score = 39.3 bits (90), Expect = 0.007
Identities = 21/51 (41%), Positives = 29/51 (56%), Gaps = 6/51 (11%)
Query: 286 PGRCK-KCSPGYQ--QVGSKCLDVDECET--EVCPGENKQCENTEGGYRCI 331
PG + +C+ G+ + +CLD+DEC T E C G+ C N GGY CI
Sbjct: 20 PGNAQAQCTNGFDLDRQSGQCLDIDECRTIPEACRGD-MMCVNQNGGYLCI 69
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 75.1 bits (183), Expect = 1e-13
Identities = 71/238 (29%), Positives = 87/238 (36%), Gaps = 56/238 (23%)
Query: 143 CPAGTFGPSCLPCPGGTERP----CGGYGQCEGEG---------TRGGSGHCDCQAGY-- 187
C G SC PG P C +CE E GGS +C C GY
Sbjct: 590 CVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRL 649
Query: 188 ----GGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKC 243
GG +C E HL F C G + NC + A C
Sbjct: 650 HVGAGGRSCVDLN------ECAKPHLCGDGGF--CINFPGHYKCNCYPGYRLKASRPPVC 701
Query: 244 VDIDECGTEGANCGADQFCVNTEGSYECRDC--------------AKACLGCMGAGPGRC 289
DIDEC + ++C D C N GS++C C C PG C
Sbjct: 702 EDIDEC-RDPSSC-PDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWC 759
Query: 290 KK--------CSPGYQQV--GSKCLDVDECET-EVCPGENKQCENTEGGYRCICAEGY 336
+ C+ GY G CLDVDECE +VC +N C NT G ++C C GY
Sbjct: 760 ENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVC--DNGICSNTPGSFQCQCLSGY 815
Score = 71.2 bits (173), Expect = 2e-12
Identities = 61/202 (30%), Positives = 78/202 (38%), Gaps = 47/202 (23%)
Query: 152 CLPCPGGTERPCGGYGQCEGEGTRG------------GSGHCDCQAGYGGEACGQCGLGY 199
C+ C G GG + E G GS C C GY G+ L
Sbjct: 727 CIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDV 786
Query: 200 FEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLK--CVDIDECGTEGANCG 257
E E VC G C+ G + CL G+ L + C DIDEC A G
Sbjct: 787 DECEAGD---VCDN--GICSNTPGSFQCQCLS---GYHLSRDRSHCEDIDECDFPAACIG 838
Query: 258 ADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGS-KCLDVDECETE--VC 314
D C+NT GSY C C G++ VG KC D+DEC + +C
Sbjct: 839 GD--CINTNGSYRCL-------------------CPQGHRLVGGRKCQDIDECSQDPSLC 877
Query: 315 PGENKQCENTEGGYRCICAEGY 336
C+N +G Y C+C EG+
Sbjct: 878 LPHGA-CKNLQGSYVCVCDEGF 898
Score = 63.2 bits (152), Expect = 4e-10
Identities = 40/118 (33%), Positives = 55/118 (46%), Gaps = 21/118 (17%)
Query: 223 GPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCGADQ-FCVNTEGSYECRDCAKACL 279
GP + +C C G+ H H CVD++EC E CG + C+NT GSY C C +
Sbjct: 593 GPPDYSC-HCNPGYRSHPQHRYCVDVNEC--EAEPCGPGRGICMNTGGSYNCH-CNRGYR 648
Query: 280 GCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
+GAG G C+D++EC G+ C N G Y+C C GY+
Sbjct: 649 LHVGAG--------------GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYR 692
Score = 55.8 bits (133), Expect = 7e-08
Identities = 35/91 (38%), Positives = 42/91 (46%), Gaps = 24/91 (26%)
Query: 245 DIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGS--K 302
DIDEC G+ + CVNT+ YEC C G+ G+ +
Sbjct: 993 DIDECMLFGSEICKEGKCVNTQPGYECY-------------------CKQGFYYDGNLLE 1033
Query: 303 CLDVDECETEV-CPGENKQCENTEGGYRCIC 332
C+DVDEC E C N CENT GGYRC C
Sbjct: 1034 CVDVDECLDESNC--RNGVCENTRGGYRCAC 1062
Score = 52.4 bits (124), Expect = 8e-07
Identities = 53/207 (25%), Positives = 82/207 (39%), Gaps = 43/207 (20%)
Query: 177 GSGHCDCQAGY-GGEACGQCGLGYFEAERNASHL-VCSACFGPCARCSGPE-------ES 227
GS C+C+ + G + C L AER VC + G C+GP +
Sbjct: 1102 GSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDD 1161
Query: 228 NCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNT--------------------EG 267
C + +GW C G++C Q N+ E
Sbjct: 1162 CCCRQGRGWGAQCRPCPPRGA----GSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEED 1217
Query: 268 SYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSK--CLDVDECETEVCPG---ENKQCE 322
S ECR + C+ G G +C G+Q S+ C+D+DEC G ++++C
Sbjct: 1218 SDECRCVSGRCVPRPG---GAVCECPGGFQLDASRARCVDIDECRELNQRGLLCKSERCV 1274
Query: 323 NTEGGYRCICAEGY--KQMEGICVKEQ 347
NT G +RC+C G+ + G CV ++
Sbjct: 1275 NTSGSFRCVCKAGFARSRPHGACVPQR 1301
Score = 51.6 bits (122), Expect = 1e-06
Identities = 39/117 (33%), Positives = 54/117 (46%), Gaps = 21/117 (17%)
Query: 220 RCSGPEESNCLQCKKGWAL--HHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKA 277
+C + CK+G+ + L+CVD+DEC E +NC + C NT G Y C A
Sbjct: 1009 KCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDE-SNC-RNGVCENTRGGYRC-----A 1061
Query: 278 CLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVC--PGENKQCENTEGGYRCIC 332
C P + + SP + +DVDEC+ PG +C N G YRC C
Sbjct: 1062 CTPPAEYSPAQRQCLSP-------EEMDVDECQDPAACRPG---RCVNLPGSYRCEC 1108
Score = 48.9 bits (115), Expect = 9e-06
Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 281 CMGAGPGRCKKCSPGYQQVGSK--CLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
C+ P C+PGY+ C+DV+ECE E C C NT G Y C C GY+
Sbjct: 590 CVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYR 648
Score = 41.2 bits (95), Expect = 0.002
Identities = 47/142 (33%), Positives = 57/142 (40%), Gaps = 29/142 (20%)
Query: 146 GTFGPSCL----PCPGGTERPCGGYGQCEGEGTRGGSGHCD---CQAGYGGEACGQCGLG 198
G+F +C P P G R C +CE CD C G C QC G
Sbjct: 764 GSFRCTCAQGYAPAPDG--RSCLDVDECEAGDV------CDNGICSNTPGSFQC-QCLSG 814
Query: 199 YFEAERNASHLV----C---SACFG-PCARCSGPEESNCLQCKKGWAL-HHLKCVDIDEC 249
Y R+ SH C +AC G C +G CL C +G L KC DIDEC
Sbjct: 815 Y-HLSRDRSHCEDIDECDFPAACIGGDCINTNG--SYRCL-CPQGHRLVGGRKCQDIDEC 870
Query: 250 GTEGANCGADQFCVNTEGSYEC 271
+ + C C N +GSY C
Sbjct: 871 SQDPSLCLPHGACKNLQGSYVC 892
Score = 39.7 bits (91), Expect = 0.005
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 8/76 (10%)
Query: 267 GSYECRDCAKA-CLGCMGAGPGRCK---KCSPGYQQVGSK-CLDVDECETE-VCPGENKQ 320
G +C C + G GP R + C GY+++ S C D++EC VC +
Sbjct: 312 GQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVC--RHGD 369
Query: 321 CENTEGGYRCICAEGY 336
C N G YRC+C G+
Sbjct: 370 CLNNPGSYRCVCPPGH 385
Score = 30.8 bits (68), Expect = 2.4
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Query: 232 CKKGWA-LHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
C +G+ L+ C DI+EC G D C+N GSY C
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHGD--CLNNPGSYRC 379
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 75.1 bits (183), Expect = 1e-13
Identities = 71/238 (29%), Positives = 87/238 (36%), Gaps = 56/238 (23%)
Query: 143 CPAGTFGPSCLPCPGGTERP----CGGYGQCEGEG---------TRGGSGHCDCQAGY-- 187
C G SC PG P C +CE E GGS +C C GY
Sbjct: 590 CVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYRL 649
Query: 188 ----GGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKC 243
GG +C E HL F C G + NC + A C
Sbjct: 650 HVGAGGRSCVDLN------ECAKPHLCGDGGF--CINFPGHYKCNCYPGYRLKASRPPVC 701
Query: 244 VDIDECGTEGANCGADQFCVNTEGSYECRDC--------------AKACLGCMGAGPGRC 289
DIDEC + ++C D C N GS++C C C PG C
Sbjct: 702 EDIDEC-RDPSSC-PDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSPGWC 759
Query: 290 KK--------CSPGYQQV--GSKCLDVDECET-EVCPGENKQCENTEGGYRCICAEGY 336
+ C+ GY G CLDVDECE +VC +N C NT G ++C C GY
Sbjct: 760 ENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAGDVC--DNGICSNTPGSFQCQCLSGY 815
Score = 71.2 bits (173), Expect = 2e-12
Identities = 61/202 (30%), Positives = 78/202 (38%), Gaps = 47/202 (23%)
Query: 152 CLPCPGGTERPCGGYGQCEGEGTRG------------GSGHCDCQAGYGGEACGQCGLGY 199
C+ C G GG + E G GS C C GY G+ L
Sbjct: 727 CIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLDV 786
Query: 200 FEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLK--CVDIDECGTEGANCG 257
E E VC G C+ G + CL G+ L + C DIDEC A G
Sbjct: 787 DECEAGD---VCDN--GICSNTPGSFQCQCLS---GYHLSRDRSHCEDIDECDFPAACIG 838
Query: 258 ADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGS-KCLDVDECETE--VC 314
D C+NT GSY C C G++ VG KC D+DEC + +C
Sbjct: 839 GD--CINTNGSYRCL-------------------CPQGHRLVGGRKCQDIDECSQDPSLC 877
Query: 315 PGENKQCENTEGGYRCICAEGY 336
C+N +G Y C+C EG+
Sbjct: 878 LPHGA-CKNLQGSYVCVCDEGF 898
Score = 63.2 bits (152), Expect = 4e-10
Identities = 40/118 (33%), Positives = 55/118 (46%), Gaps = 21/118 (17%)
Query: 223 GPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCGADQ-FCVNTEGSYECRDCAKACL 279
GP + +C C G+ H H CVD++EC E CG + C+NT GSY C C +
Sbjct: 593 GPPDYSC-HCNPGYRSHPQHRYCVDVNEC--EAEPCGPGRGICMNTGGSYNCH-CNRGYR 648
Query: 280 GCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
+GAG G C+D++EC G+ C N G Y+C C GY+
Sbjct: 649 LHVGAG--------------GRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYR 692
Score = 55.8 bits (133), Expect = 7e-08
Identities = 35/91 (38%), Positives = 42/91 (46%), Gaps = 24/91 (26%)
Query: 245 DIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGS--K 302
DIDEC G+ + CVNT+ YEC C G+ G+ +
Sbjct: 993 DIDECMLFGSEICKEGKCVNTQPGYECY-------------------CKQGFYYDGNLLE 1033
Query: 303 CLDVDECETEV-CPGENKQCENTEGGYRCIC 332
C+DVDEC E C N CENT GGYRC C
Sbjct: 1034 CVDVDECLDESNC--RNGVCENTRGGYRCAC 1062
Score = 49.3 bits (116), Expect = 7e-06
Identities = 59/213 (27%), Positives = 84/213 (39%), Gaps = 47/213 (22%)
Query: 172 EGTRGGSGHCDCQ--AGYGGEACGQCGLGYFEAERNASHL-VCSACFGPCARCSGPE--- 225
E TRGG C C A Y A QC L E ER VC + G C+GP
Sbjct: 1052 ENTRGGY-RCACTPPAEYS-PAQRQC-LSPEEMERAPERRDVCWSQRGEDGMCAGPLAGP 1108
Query: 226 ----ESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNT---------------- 265
+ C + +GW C G++C Q N+
Sbjct: 1109 ALTFDDCCCRQGRGWGAQCRPCPPRGA----GSHCPTSQSESNSFWDTSPLLLGKPPRDE 1164
Query: 266 ----EGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSK--CLDVDECETEVCPG--- 316
E S ECR + C+ G G +C G+Q S+ C+D+DEC G
Sbjct: 1165 DSSEEDSDECRCVSGRCVPRPG---GAVCECPGGFQLDASRARCVDIDECRELNQRGLLC 1221
Query: 317 ENKQCENTEGGYRCICAEGY--KQMEGICVKEQ 347
++++C NT G +RC+C G+ + G CV ++
Sbjct: 1222 KSERCVNTSGSFRCVCKAGFARSRPHGACVPQR 1254
Score = 48.9 bits (115), Expect = 9e-06
Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 281 CMGAGPGRCKKCSPGYQQVGSK--CLDVDECETEVCPGENKQCENTEGGYRCICAEGYK 337
C+ P C+PGY+ C+DV+ECE E C C NT G Y C C GY+
Sbjct: 590 CVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICMNTGGSYNCHCNRGYR 648
Score = 41.2 bits (95), Expect = 0.002
Identities = 47/142 (33%), Positives = 57/142 (40%), Gaps = 29/142 (20%)
Query: 146 GTFGPSCL----PCPGGTERPCGGYGQCEGEGTRGGSGHCD---CQAGYGGEACGQCGLG 198
G+F +C P P G R C +CE CD C G C QC G
Sbjct: 764 GSFRCTCAQGYAPAPDG--RSCLDVDECEAGDV------CDNGICSNTPGSFQC-QCLSG 814
Query: 199 YFEAERNASHLV----C---SACFG-PCARCSGPEESNCLQCKKGWAL-HHLKCVDIDEC 249
Y R+ SH C +AC G C +G CL C +G L KC DIDEC
Sbjct: 815 Y-HLSRDRSHCEDIDECDFPAACIGGDCINTNG--SYRCL-CPQGHRLVGGRKCQDIDEC 870
Query: 250 GTEGANCGADQFCVNTEGSYEC 271
+ + C C N +GSY C
Sbjct: 871 SQDPSLCLPHGACKNLQGSYVC 892
Score = 39.7 bits (91), Expect = 0.005
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 8/76 (10%)
Query: 267 GSYECRDCAKA-CLGCMGAGPGRCK---KCSPGYQQVGSK-CLDVDECETE-VCPGENKQ 320
G +C C + G GP R + C GY+++ S C D++EC VC +
Sbjct: 312 GQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVC--RHGD 369
Query: 321 CENTEGGYRCICAEGY 336
C N G YRC+C G+
Sbjct: 370 CLNNPGSYRCVCPPGH 385
Score = 37.4 bits (85), Expect = 0.026
Identities = 35/123 (28%), Positives = 52/123 (42%), Gaps = 18/123 (14%)
Query: 220 RCSGPEESNCLQCKKGWAL--HHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKA 277
+C + CK+G+ + L+CVD+DEC E +NC + C NT G Y C A
Sbjct: 1009 KCVNTQPGYECYCKQGFYYDGNLLECVDVDECLDE-SNC-RNGVCENTRGGYRC-----A 1061
Query: 278 CLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYR-----CIC 332
C P + + SP + + DV C ++ GE+ C G C C
Sbjct: 1062 CTPPAEYSPAQRQCLSPEEMERAPERRDV--CWSQ--RGEDGMCAGPLAGPALTFDDCCC 1117
Query: 333 AEG 335
+G
Sbjct: 1118 RQG 1120
Score = 30.8 bits (68), Expect = 2.4
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 3/41 (7%)
Query: 232 CKKGWA-LHHLKCVDIDECGTEGANCGADQFCVNTEGSYEC 271
C +G+ L+ C DI+EC G D C+N GSY C
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHGD--CLNNPGSYRC 379
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 74.7 bits (182), Expect = 1e-13
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 18/111 (16%)
Query: 230 LQCKKGWALHHL-KCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGR 288
LQCK G+ L C+DI+EC + A C C+NTEGSY C+
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQK--------------N 337
Query: 289 CKKCSPGY--QQVGSKCLDVDECETEVCP-GENKQCENTEGGYRCICAEGY 336
C GY + G++C+DVDEC P G+ +C N+ G +RC C GY
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388
Score = 68.2 bits (165), Expect = 1e-11
Identities = 59/220 (26%), Positives = 87/220 (39%), Gaps = 61/220 (27%)
Query: 177 GSGHC----DCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCA---RCSGPEES-- 227
GS C C++G+ +A G C + N C + PC C E S
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNC------IDINE----CLSISAPCPIGHTCINTEGSYT 333
Query: 228 ---NCLQCKKGWALHH--LKCVDIDECGTEGANCGADQFCVNTEGSYEC----------- 271
N C +G+ L+ +CVD+DEC CG CVN+ GS+ C
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 272 ---------------RDCAKACLGCMGAGPGRCKKCSPGYQQV--GSKCLDVDECETEVC 314
R C C +G+ CS G++ G C D++EC + C
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGS---YLCSCSVGFRLSVDGRSCEDINECSSSPC 450
Query: 315 PGENKQCENTEGGYRCICAEGYK--QMEGICVKEQIPESA 352
+++C N G Y+C C GY+ ++G+ E I E A
Sbjct: 451 ---SQECANVYGSYQCYCRRGYQLSDVDGVTC-EDIDECA 486
Score = 61.6 bits (148), Expect = 1e-09
Identities = 57/214 (26%), Positives = 82/214 (38%), Gaps = 54/214 (25%)
Query: 162 PCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARC 221
PCG +C GS C+C+ GY + + + E +R L C C
Sbjct: 366 PCGKGHRCVNSP---GSFRCECKTGYYFDGISRMCVDVNECQRYPGRL----CGHKCENT 418
Query: 222 SGPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCGADQFCVNTEGSYEC-------- 271
G S C G+ L C DI+EC + + Q C N GSY+C
Sbjct: 419 LG---SYLCSCSVGFRLSVDGRSCEDINECSSSPCS----QECANVYGSYQCYCRRGYQL 471
Query: 272 --------------------RDCAKACLGCMGAGPGRCKKCSPGYQQV--GSKCLDVDEC 309
C+ C+ G+ +C S GY+ G C D+DEC
Sbjct: 472 SDVDGVTCEDIDECALPTGGHICSYRCINIPGSF--QCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 310 ETEV--CPGENKQCENTEGGYRCI---CAEGYKQ 338
T + C N+ C N +GG+RC+ C E Y++
Sbjct: 530 VTGIHNC-SINETCFNIQGGFRCLAFECPENYRR 562
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 74.7 bits (182), Expect = 1e-13
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 18/111 (16%)
Query: 230 LQCKKGWALHHL-KCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGR 288
LQCK G+ L C+DI+EC + A C C+NTEGSY C+
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQK--------------N 337
Query: 289 CKKCSPGY--QQVGSKCLDVDECETEVCP-GENKQCENTEGGYRCICAEGY 336
C GY + G++C+DVDEC P G+ +C N+ G +RC C GY
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388
Score = 68.2 bits (165), Expect = 1e-11
Identities = 59/220 (26%), Positives = 87/220 (39%), Gaps = 61/220 (27%)
Query: 177 GSGHC----DCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCA---RCSGPEES-- 227
GS C C++G+ +A G C + N C + PC C E S
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNC------IDINE----CLSISAPCPIGHTCINTEGSYT 333
Query: 228 ---NCLQCKKGWALHH--LKCVDIDECGTEGANCGADQFCVNTEGSYEC----------- 271
N C +G+ L+ +CVD+DEC CG CVN+ GS+ C
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 272 ---------------RDCAKACLGCMGAGPGRCKKCSPGYQQV--GSKCLDVDECETEVC 314
R C C +G+ CS G++ G C D++EC + C
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGS---YLCSCSVGFRLSVDGRSCEDINECSSSPC 450
Query: 315 PGENKQCENTEGGYRCICAEGYK--QMEGICVKEQIPESA 352
+++C N G Y+C C GY+ ++G+ E I E A
Sbjct: 451 ---SQECANVYGSYQCYCRRGYQLSDVDGVTC-EDIDECA 486
Score = 61.6 bits (148), Expect = 1e-09
Identities = 57/214 (26%), Positives = 82/214 (38%), Gaps = 54/214 (25%)
Query: 162 PCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARC 221
PCG +C GS C+C+ GY + + + E +R L C C
Sbjct: 366 PCGKGHRCVNSP---GSFRCECKTGYYFDGISRMCVDVNECQRYPGRL----CGHKCENT 418
Query: 222 SGPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCGADQFCVNTEGSYEC-------- 271
G S C G+ L C DI+EC + + Q C N GSY+C
Sbjct: 419 LG---SYLCSCSVGFRLSVDGRSCEDINECSSSPCS----QECANVYGSYQCYCRRGYQL 471
Query: 272 --------------------RDCAKACLGCMGAGPGRCKKCSPGYQQV--GSKCLDVDEC 309
C+ C+ G+ +C S GY+ G C D+DEC
Sbjct: 472 SDVDGVTCEDIDECALPTGGHICSYRCINIPGSF--QCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 310 ETEV--CPGENKQCENTEGGYRCI---CAEGYKQ 338
T + C N+ C N +GG+RC+ C E Y++
Sbjct: 530 VTGIHNC-SINETCFNIQGGFRCLAFECPENYRR 562
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 74.7 bits (182), Expect = 1e-13
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 18/111 (16%)
Query: 230 LQCKKGWALHHL-KCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGR 288
LQCK G+ L C+DI+EC + A C C+NTEGSY C+
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQK--------------N 337
Query: 289 CKKCSPGY--QQVGSKCLDVDECETEVCP-GENKQCENTEGGYRCICAEGY 336
C GY + G++C+DVDEC P G+ +C N+ G +RC C GY
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388
Score = 68.2 bits (165), Expect = 1e-11
Identities = 59/220 (26%), Positives = 87/220 (39%), Gaps = 61/220 (27%)
Query: 177 GSGHC----DCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCA---RCSGPEES-- 227
GS C C++G+ +A G C + N C + PC C E S
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNC------IDINE----CLSISAPCPIGHTCINTEGSYT 333
Query: 228 ---NCLQCKKGWALHH--LKCVDIDECGTEGANCGADQFCVNTEGSYEC----------- 271
N C +G+ L+ +CVD+DEC CG CVN+ GS+ C
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 272 ---------------RDCAKACLGCMGAGPGRCKKCSPGYQQV--GSKCLDVDECETEVC 314
R C C +G+ CS G++ G C D++EC + C
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGS---YLCSCSVGFRLSVDGRSCEDINECSSSPC 450
Query: 315 PGENKQCENTEGGYRCICAEGYK--QMEGICVKEQIPESA 352
+++C N G Y+C C GY+ ++G+ E I E A
Sbjct: 451 ---SQECANVYGSYQCYCRRGYQLSDVDGVTC-EDIDECA 486
Score = 62.0 bits (149), Expect = 1e-09
Identities = 58/223 (26%), Positives = 85/223 (38%), Gaps = 54/223 (24%)
Query: 162 PCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARC 221
PCG +C GS C+C+ GY + + + E +R L C C
Sbjct: 366 PCGKGHRCVNSP---GSFRCECKTGYYFDGISRMCVDVNECQRYPGRL----CGHKCENT 418
Query: 222 SGPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCGADQFCVNTEGSYEC-------- 271
G S C G+ L C DI+EC + + Q C N GSY+C
Sbjct: 419 LG---SYLCSCSVGFRLSVDGRSCEDINECSSSPCS----QECANVYGSYQCYCRRGYQL 471
Query: 272 --------------------RDCAKACLGCMGAGPGRCKKCSPGYQQV--GSKCLDVDEC 309
C+ C+ G+ +C S GY+ G C D+DEC
Sbjct: 472 SDVDGVTCEDIDECALPTGGHICSYRCINIPGSF--QCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 310 ETEV--CPGENKQCENTEGGYRCI---CAEGYKQMEGICVKEQ 347
T + C N+ C N +GG+RC+ C E Y++ +E+
Sbjct: 530 VTGIHNC-SINETCFNIQGGFRCLAFECPENYRRSAATLQQEK 571
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 74.7 bits (182), Expect = 1e-13
Identities = 41/111 (36%), Positives = 55/111 (49%), Gaps = 18/111 (16%)
Query: 230 LQCKKGWALHHL-KCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGR 288
LQCK G+ L C+DI+EC + A C C+NTEGSY C+
Sbjct: 292 LQCKSGFIQDALGNCIDINECLSISAPCPIGHTCINTEGSYTCQK--------------N 337
Query: 289 CKKCSPGY--QQVGSKCLDVDECETEVCP-GENKQCENTEGGYRCICAEGY 336
C GY + G++C+DVDEC P G+ +C N+ G +RC C GY
Sbjct: 338 VPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGY 388
Score = 68.2 bits (165), Expect = 1e-11
Identities = 59/220 (26%), Positives = 87/220 (39%), Gaps = 61/220 (27%)
Query: 177 GSGHC----DCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCA---RCSGPEES-- 227
GS C C++G+ +A G C + N C + PC C E S
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNC------IDINE----CLSISAPCPIGHTCINTEGSYT 333
Query: 228 ---NCLQCKKGWALHH--LKCVDIDECGTEGANCGADQFCVNTEGSYEC----------- 271
N C +G+ L+ +CVD+DEC CG CVN+ GS+ C
Sbjct: 334 CQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFRCECKTGYYFDGI 393
Query: 272 ---------------RDCAKACLGCMGAGPGRCKKCSPGYQQV--GSKCLDVDECETEVC 314
R C C +G+ CS G++ G C D++EC + C
Sbjct: 394 SRMCVDVNECQRYPGRLCGHKCENTLGS---YLCSCSVGFRLSVDGRSCEDINECSSSPC 450
Query: 315 PGENKQCENTEGGYRCICAEGYK--QMEGICVKEQIPESA 352
+++C N G Y+C C GY+ ++G+ E I E A
Sbjct: 451 ---SQECANVYGSYQCYCRRGYQLSDVDGVTC-EDIDECA 486
Score = 61.6 bits (148), Expect = 1e-09
Identities = 57/214 (26%), Positives = 82/214 (38%), Gaps = 54/214 (25%)
Query: 162 PCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARC 221
PCG +C GS C+C+ GY + + + E +R L C C
Sbjct: 366 PCGKGHRCVNSP---GSFRCECKTGYYFDGISRMCVDVNECQRYPGRL----CGHKCENT 418
Query: 222 SGPEESNCLQCKKGWALH--HLKCVDIDECGTEGANCGADQFCVNTEGSYEC-------- 271
G S C G+ L C DI+EC + + Q C N GSY+C
Sbjct: 419 LG---SYLCSCSVGFRLSVDGRSCEDINECSSSPCS----QECANVYGSYQCYCRRGYQL 471
Query: 272 --------------------RDCAKACLGCMGAGPGRCKKCSPGYQQV--GSKCLDVDEC 309
C+ C+ G+ +C S GY+ G C D+DEC
Sbjct: 472 SDVDGVTCEDIDECALPTGGHICSYRCINIPGSF--QCSCPSSGYRLAPNGRNCQDIDEC 529
Query: 310 ETEV--CPGENKQCENTEGGYRCI---CAEGYKQ 338
T + C N+ C N +GG+RC+ C E Y++
Sbjct: 530 VTGIHNC-SINETCFNIQGGFRCLAFECPENYRR 562
>gi|88758613 CD93 antigen precursor [Homo sapiens]
Length = 652
Score = 73.2 bits (178), Expect = 4e-13
Identities = 70/259 (27%), Positives = 102/259 (39%), Gaps = 59/259 (22%)
Query: 110 ELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQC 169
E ++ +S +F +++APD+F W G+ GP C+ G GG C
Sbjct: 227 EGDKDETQSHYFLCKEKAPDVFDW------------GSSGPLCVSPKYGCNFNNGG---C 271
Query: 170 EGEGTRGGSGH--CDCQAGYGG-EACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEE 226
+ GG G C C+ G+ + C A RN S C G GP
Sbjct: 272 HQDCFEGGDGSFLCGCRPGFRLLDDLVTC------ASRNPCS--SSPCRGGATCVLGPHG 323
Query: 227 SN-CLQCKKGWALH--HLKCVDIDECGTEGANCGADQFCVNTEGSYECR----------- 272
N +C +G+ L L CVD+DEC + + C Q CVNT G + C
Sbjct: 324 KNYTCRCPQGYQLDSSQLDCVDVDEC--QDSPCA--QECVNTPGGFRCECWVGYEPGGPG 379
Query: 273 ---------------DCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGE 317
CA+ C G+ C++ + G++C DVDEC P
Sbjct: 380 EGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLC 439
Query: 318 NKQCENTEGGYRCICAEGY 336
+ C NT+G + C C G+
Sbjct: 440 DSLCFNTQGSFHCGCLPGW 458
>gi|56550049 uromodulin precursor [Homo sapiens]
Length = 640
Score = 71.2 bits (173), Expect = 2e-12
Identities = 46/134 (34%), Positives = 58/134 (43%), Gaps = 30/134 (22%)
Query: 211 CSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGA-NCGADQFCVNTEGSY 269
CS C A C+ E C++G+ L CVD+DEC GA NC A+ CVNT GS+
Sbjct: 32 CSECHSN-ATCTEDEAVTTCTCQEGFTGDGLTCVDLDECAIPGAHNCSANSSCVNTPGSF 90
Query: 270 ECRDCAKACLGCMGAGPGRCKKCSPGYQ-QVGSKCLDVDECETEVCPGEN-----KQCEN 323
C C G++ G C DVDEC PG + C N
Sbjct: 91 SC-------------------VCPEGFRLSPGLGCTDVDECAE---PGLSHCHALATCVN 128
Query: 324 TEGGYRCICAEGYK 337
G Y C+C GY+
Sbjct: 129 VVGSYLCVCPAGYR 142
Score = 44.3 bits (103), Expect = 2e-04
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 8/56 (14%)
Query: 292 CSPGYQQVGSKCLDVDECETEVCPGE-----NKQCENTEGGYRCICAEGYKQMEGI 342
C G+ G C+D+DEC PG N C NT G + C+C EG++ G+
Sbjct: 52 CQEGFTGDGLTCVDLDEC---AIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGL 104
Score = 28.9 bits (63), Expect = 9.1
Identities = 55/243 (22%), Positives = 79/243 (32%), Gaps = 54/243 (22%)
Query: 138 SLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRG---GSGHCDCQAGYGGE---- 190
S CP G L C E G C T GS C C AGY G+
Sbjct: 89 SFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVNVVGSYLCVCPAGYRGDGWHC 148
Query: 191 --ACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEE----------SNCLQCKKGW-- 236
+ G CG G + LVC+ PC +E C +GW
Sbjct: 149 ECSPGSCGPG-LDCVPEGDALVCA---DPCQAHRTLDEYWRSTEYGEGYACDTDLRGWYR 204
Query: 237 ------ALHHLKCVDIDECGT------EGANCGADQFCVNTEGSYECRDCAKACLGCMGA 284
A CV + C T G + +D+ V+ + C + C C+
Sbjct: 205 FVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKA---CAHWSGHC--CLWD 259
Query: 285 GPGRCKKCSPGYQQVG---------SKCLDVDECE--TEVCPGENKQCENTEGGYRCICA 333
+ K C+ GY + C D E E C ++ C++ G + C C
Sbjct: 260 ASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEEC-SIDEDCKSNNGRWHCQCK 318
Query: 334 EGY 336
+ +
Sbjct: 319 QDF 321
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.139 0.478
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,080,676
Number of Sequences: 37866
Number of extensions: 1390539
Number of successful extensions: 15765
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 203
Number of HSP's successfully gapped in prelim test: 482
Number of HSP's that attempted gapping in prelim test: 10920
Number of HSP's gapped (non-prelim): 3442
length of query: 420
length of database: 18,247,518
effective HSP length: 105
effective length of query: 315
effective length of database: 14,271,588
effective search space: 4495550220
effective search space used: 4495550220
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.