Guide to the Human Genome
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Search of human proteins with 239742533

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239742533 PREDICTED: hypothetical protein LOC100129791 [Homo
sapiens]
         (338 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239748549 PREDICTED: hypothetical protein LOC100129791 [Homo ...   669   0.0  
gi|239742533 PREDICTED: hypothetical protein LOC100129791 [Homo ...   669   0.0  
gi|239754018 PREDICTED: hypothetical protein LOC100129791 [Homo ...   662   0.0  
gi|157694505 LINE-1 type transposase domain containing 1 [Homo s...   165   6e-41
gi|239751946 PREDICTED: hypothetical protein XP_002348046 [Homo ...   136   3e-32
gi|239746429 PREDICTED: hypothetical protein XP_002344210 [Homo ...   136   3e-32
gi|239757430 PREDICTED: similar to lactation elevated 1 (predict...   135   4e-32
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]                     52   6e-07
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]                     52   6e-07
gi|122937514 unc-13 homolog C [Homo sapiens]                           52   1e-06
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    50   2e-06
gi|149363685 hypothetical protein LOC23379 [Homo sapiens]              50   4e-06
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    49   6e-06
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    49   6e-06
gi|154354990 ankyrin repeat domain 26 [Homo sapiens]                   48   1e-05
gi|38044112 restin isoform b [Homo sapiens]                            47   2e-05
gi|4506751 restin isoform a [Homo sapiens]                             47   2e-05
gi|45439327 periplakin [Homo sapiens]                                  47   2e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     46   4e-05
gi|71061468 centromere protein E [Homo sapiens]                        46   5e-05
gi|214010216 SMC6 protein [Homo sapiens]                               46   5e-05
gi|13375848 SMC6 protein [Homo sapiens]                                46   5e-05
gi|31982906 cingulin-like 1 [Homo sapiens]                             45   7e-05
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       45   9e-05
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       45   9e-05
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        45   9e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    45   9e-05
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    45   9e-05
gi|45446749 kinesin family member 5A [Homo sapiens]                    45   1e-04
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi...    45   1e-04

>gi|239748549 PREDICTED: hypothetical protein LOC100129791 [Homo
           sapiens]
          Length = 338

 Score =  669 bits (1726), Expect = 0.0
 Identities = 338/338 (100%), Positives = 338/338 (100%)

Query: 1   MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60
           MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ
Sbjct: 1   MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60

Query: 61  TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA 120
           TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA
Sbjct: 61  TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA 120

Query: 121 MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
           MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD
Sbjct: 121 MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180

Query: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
           IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV
Sbjct: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240

Query: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300
           TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK
Sbjct: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300

Query: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
           QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM
Sbjct: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338


>gi|239742533 PREDICTED: hypothetical protein LOC100129791 [Homo
           sapiens]
          Length = 338

 Score =  669 bits (1726), Expect = 0.0
 Identities = 338/338 (100%), Positives = 338/338 (100%)

Query: 1   MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60
           MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ
Sbjct: 1   MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60

Query: 61  TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA 120
           TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA
Sbjct: 61  TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA 120

Query: 121 MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
           MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD
Sbjct: 121 MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180

Query: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
           IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV
Sbjct: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240

Query: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300
           TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK
Sbjct: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300

Query: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
           QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM
Sbjct: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338


>gi|239754018 PREDICTED: hypothetical protein LOC100129791 [Homo
           sapiens]
          Length = 338

 Score =  662 bits (1709), Expect = 0.0
 Identities = 335/338 (99%), Positives = 336/338 (99%)

Query: 1   MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60
           MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ
Sbjct: 1   MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQ 60

Query: 61  TKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSA 120
           TKGK+VENFEKNLEECITRITNTEKCLKELMELKTKAREL EECRSLRSRCDQLEERVSA
Sbjct: 61  TKGKEVENFEKNLEECITRITNTEKCLKELMELKTKARELCEECRSLRSRCDQLEERVSA 120

Query: 121 MEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
           MEDEMNEMKQEGK REKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD
Sbjct: 121 MEDEMNEMKQEGKFREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180

Query: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
           IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV
Sbjct: 181 IIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240

Query: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300
           TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK
Sbjct: 241 TLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDK 300

Query: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
           QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM
Sbjct: 301 QMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338


>gi|157694505 LINE-1 type transposase domain containing 1 [Homo
           sapiens]
          Length = 865

 Score =  165 bits (417), Expect = 6e-41
 Identities = 94/254 (37%), Positives = 149/254 (58%), Gaps = 7/254 (2%)

Query: 67  ENFEKNLEECITRITNTEKCLKELMELKTK---ARELREECRSLRSRCDQLEERVSAMED 123
           E  E+NL   +  I +  +  +E+  LK+      E+      L SR D LEER+ ++ED
Sbjct: 611 EETEENLRSSV--INSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLED 668

Query: 124 EMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQ 183
           ++ E  ++     K+I   E+  ++I +  +  N+RLIG+PE  E    + E+ +++II 
Sbjct: 669 QIEEFSKDTMQMTKQIISKERQ-RDIEERSRSCNIRLIGIPEK-ESYENRAEDIIKEIID 726

Query: 184 ENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLK 243
           ENF  L + ++++I    R+  +   +R TPRHI+V+F     KEK++RA+RE+  +T +
Sbjct: 727 ENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQ 786

Query: 244 GKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQML 303
           G  IRLTADLS +TL AR +W  +F +L EK F PRI Y AK++F   G+ K F+  +  
Sbjct: 787 GTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEF 846

Query: 304 RDFVTTRPALQELL 317
           RD+V   P L+ELL
Sbjct: 847 RDYVLHMPTLRELL 860



 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 42/102 (41%), Positives = 69/102 (67%)

Query: 220 RFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPR 279
           +F K++ KE++L+A+RE+  +  +G  + L ADLS+ TL   ++W  +FNIL+E +F+P+
Sbjct: 216 KFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPK 275

Query: 280 ISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEAL 321
                KL+F  +GEIK F D Q LR F + + +++ELLK+ L
Sbjct: 276 FLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVL 317


>gi|239751946 PREDICTED: hypothetical protein XP_002348046 [Homo
           sapiens]
          Length = 132

 Score =  136 bits (342), Expect = 3e-32
 Identities = 70/132 (53%), Positives = 94/132 (71%), Gaps = 3/132 (2%)

Query: 1   MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRR---SNYSELRE 57
           M K Q +K  NSK Q+AS PPK+ +SSPA EQ W  N+FDEL E GFRR   +N S+L+E
Sbjct: 1   MRKNQCKKAENSKNQNASSPPKDHNSSPAREQDWTGNEFDELTEVGFRRWVITNSSKLKE 60

Query: 58  DIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEER 117
            + T+ K+V+N EK L++ +T I + EK + +LMELK  ARELRE   S+ SR DQ EER
Sbjct: 61  HVLTQCKEVKNLEKRLDKLLTGINSLEKNINDLMELKNTARELREAYTSINSRIDQAEER 120

Query: 118 VSAMEDEMNEMK 129
           +S +ED++NE+K
Sbjct: 121 ISEIEDQLNEIK 132


>gi|239746429 PREDICTED: hypothetical protein XP_002344210 [Homo
           sapiens]
          Length = 132

 Score =  136 bits (342), Expect = 3e-32
 Identities = 70/132 (53%), Positives = 94/132 (71%), Gaps = 3/132 (2%)

Query: 1   MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRR---SNYSELRE 57
           M K Q +K  NSK Q+AS PPK+ +SSPA EQ W  N+FDEL E GFRR   +N S+L+E
Sbjct: 1   MRKNQCKKAENSKNQNASSPPKDHNSSPAREQDWTGNEFDELTEVGFRRWVITNSSKLKE 60

Query: 58  DIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEER 117
            + T+ K+V+N EK L++ +T I + EK + +LMELK  ARELRE   S+ SR DQ EER
Sbjct: 61  HVLTQCKEVKNLEKRLDKLLTGINSLEKNINDLMELKNTARELREAYTSINSRIDQAEER 120

Query: 118 VSAMEDEMNEMK 129
           +S +ED++NE+K
Sbjct: 121 ISEIEDQLNEIK 132


>gi|239757430 PREDICTED: similar to lactation elevated 1 (predicted)
           [Homo sapiens]
          Length = 132

 Score =  135 bits (341), Expect = 4e-32
 Identities = 70/132 (53%), Positives = 94/132 (71%), Gaps = 3/132 (2%)

Query: 1   MGKKQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRR---SNYSELRE 57
           M K Q +K  NSK Q+AS PPK+ +SSPA EQ W  N+FDEL E GFRR   +N S+L+E
Sbjct: 1   MRKNQCKKAENSKNQNASSPPKDHNSSPAREQDWTGNEFDELTEIGFRRWVITNSSKLKE 60

Query: 58  DIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEER 117
            + T+ K+V+N EK L++ +T I + EK + +LMELK  ARELRE   S+ SR DQ EER
Sbjct: 61  HVLTQCKEVKNLEKRLDKLLTGINSLEKNINDLMELKNTARELREAYTSINSRIDQAEER 120

Query: 118 VSAMEDEMNEMK 129
           +S +ED++NE+K
Sbjct: 121 ISEIEDQLNEIK 132


>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
          Length = 1173

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 55/241 (22%), Positives = 111/241 (46%), Gaps = 33/241 (13%)

Query: 22  KECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRIT 81
           +E S+ P +E   ++  FDE+  A         LR+  QT+G+KV+ ++  L        
Sbjct: 20  QEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVKEYQMEL-------- 71

Query: 82  NTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKR 141
                 K L + K KA E+R++  S  ++    +E V + E+E++ +K     R K I+ 
Sbjct: 72  ------KYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKN----RLKEIEH 121

Query: 142 NEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQ 201
           N   + ++ + +K  + R     +  E++ ++LE  ++ + Q          + Q+ ++ 
Sbjct: 122 NLSKIMKLDNEIKALDSR----KKQMEKDNSELEEKMEKVFQ--------GTDEQLNDLY 169

Query: 202 RMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAA-REKGRVTLKGKPIRLTADLSAETLQA 260
              QR  + R   R ++    ++E   K  R   +EK  + ++   ++L AD   E ++A
Sbjct: 170 HNHQR--TVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRA 227

Query: 261 R 261
           R
Sbjct: 228 R 228



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 48/238 (20%), Positives = 98/238 (41%), Gaps = 32/238 (13%)

Query: 58   DIQTKGKKVENFEKNLEECIT---------RITNTEKCLKELMELKTKARELREECRSLR 108
            DI+ K K +  + K++E  I          + T   K + +L E +    ++ E+ R +R
Sbjct: 807  DIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMRLMR 866

Query: 109  SRCD-----------------QLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWD 151
               D                 + EE     E+    +K+ G+++  ++K   Q L+E  D
Sbjct: 867  QDIDTQKIQERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQMKSEHQKLEENID 926

Query: 152  YVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRR 211
             +KR +   +G  +  EE     +  L++    +     R+  I ++  + +++      
Sbjct: 927  NIKRNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYY 986

Query: 212  ATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGK-----PIRLTADLSAETLQARREW 264
             T    I++F  ++M E++ +  R+  R T +G+      IR  AD +      RR +
Sbjct: 987  KTLDQAIMKFHSMKM-EEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNY 1043



 Score = 28.9 bits (63), Expect = 6.8
 Identities = 31/172 (18%), Positives = 67/172 (38%), Gaps = 11/172 (6%)

Query: 49  RSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKEL-------MELKTKARELR 101
           R+    +  DIQ     +E  E  L   +    + + CL ++       MELK   R++ 
Sbjct: 612 RNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIA 671

Query: 102 EECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLI 161
           ++   L+     L+  V  +  E  E + +      +I+ N + +Q+  + ++       
Sbjct: 672 QQAAKLQG--IDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTN 729

Query: 162 GVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRAT 213
            +     +  T L+   Q  ++E    L+ +     +EI+   ++ S    T
Sbjct: 730 ELKSEKLQISTNLQRRQQ--LEEQTVELSTEVQSLYREIKDAKEQVSPLETT 779


>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
          Length = 1312

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 55/241 (22%), Positives = 111/241 (46%), Gaps = 33/241 (13%)

Query: 22  KECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRIT 81
           +E S+ P +E   ++  FDE+  A         LR+  QT+G+KV+ ++  L        
Sbjct: 159 QEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVKEYQMEL-------- 210

Query: 82  NTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKR 141
                 K L + K KA E+R++  S  ++    +E V + E+E++ +K     R K I+ 
Sbjct: 211 ------KYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKN----RLKEIEH 260

Query: 142 NEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQ 201
           N   + ++ + +K  + R     +  E++ ++LE  ++ + Q          + Q+ ++ 
Sbjct: 261 NLSKIMKLDNEIKALDSR----KKQMEKDNSELEEKMEKVFQ--------GTDEQLNDLY 308

Query: 202 RMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAA-REKGRVTLKGKPIRLTADLSAETLQA 260
              QR  + R   R ++    ++E   K  R   +EK  + ++   ++L AD   E ++A
Sbjct: 309 HNHQR--TVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRA 366

Query: 261 R 261
           R
Sbjct: 367 R 367



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 48/238 (20%), Positives = 98/238 (41%), Gaps = 32/238 (13%)

Query: 58   DIQTKGKKVENFEKNLEECIT---------RITNTEKCLKELMELKTKARELREECRSLR 108
            DI+ K K +  + K++E  I          + T   K + +L E +    ++ E+ R +R
Sbjct: 946  DIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINEDMRLMR 1005

Query: 109  SRCD-----------------QLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWD 151
               D                 + EE     E+    +K+ G+++  ++K   Q L+E  D
Sbjct: 1006 QDIDTQKIQERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQMKSEHQKLEENID 1065

Query: 152  YVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRR 211
             +KR +   +G  +  EE     +  L++    +     R+  I ++  + +++      
Sbjct: 1066 NIKRNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKDLDIYY 1125

Query: 212  ATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGK-----PIRLTADLSAETLQARREW 264
             T    I++F  ++M E++ +  R+  R T +G+      IR  AD +      RR +
Sbjct: 1126 KTLDQAIMKFHSMKM-EEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRRNY 1182



 Score = 28.9 bits (63), Expect = 6.8
 Identities = 31/172 (18%), Positives = 67/172 (38%), Gaps = 11/172 (6%)

Query: 49  RSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKEL-------MELKTKARELR 101
           R+    +  DIQ     +E  E  L   +    + + CL ++       MELK   R++ 
Sbjct: 751 RNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIA 810

Query: 102 EECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLI 161
           ++   L+     L+  V  +  E  E + +      +I+ N + +Q+  + ++       
Sbjct: 811 QQAAKLQG--IDLDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTN 868

Query: 162 GVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRAT 213
            +     +  T L+   Q  ++E    L+ +     +EI+   ++ S    T
Sbjct: 869 ELKSEKLQISTNLQRRQQ--LEEQTVELSTEVQSLYREIKDAKEQVSPLETT 918


>gi|122937514 unc-13 homolog C [Homo sapiens]
          Length = 2214

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 43/186 (23%), Positives = 89/186 (47%), Gaps = 22/186 (11%)

Query: 85  KCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQ 144
           K L+ + +++T+  ELR    +L+   D++   V  ++ E+ +++  G V+ +R  R   
Sbjct: 248 KELQGISQIETELSELRGHVNALKHSIDEISSSVEVVQSEIEQLRT-GFVQSRRETR--- 303

Query: 145 SLQEIWDYVK-------RPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQI 197
              +I DY+K       + +LR + V E   E    +E+ +  I+ +          I+I
Sbjct: 304 ---DIHDYIKHLGHMGSKASLRFLNVTE---ERFEYVESVVYQILIDKMGFSDAPNAIKI 357

Query: 198 QEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAET 257
           +  QR+  +     A PR I+V F   + ++ +L+ + +     LKG  I ++ D+    
Sbjct: 358 EFAQRIGHQRDCPNAKPRPILVYFETPQQRDSVLKKSYK-----LKGTGIGISTDILTHD 412

Query: 258 LQARRE 263
           ++ R+E
Sbjct: 413 IRERKE 418


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 57/267 (21%), Positives = 115/267 (43%), Gaps = 29/267 (10%)

Query: 23   ECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENF---EKNLEECITR 79
            ECS S   EQ  +E +   L+       N  E +E +Q   K  ++    E  L+E IT+
Sbjct: 1136 ECSHSAKLEQDILEKESIILK----LERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQ 1191

Query: 80   ITNTEKCLKELMELKTKARE--------LREECRSLRSRCDQLEERVSAMEDEMNEMKQE 131
            +TN  + +K L++LK +  E        L+EE  +  +R   L+  +   E++  ++K++
Sbjct: 1192 LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEK 1251

Query: 132  GKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLAR 191
                +K+IK+ ++ +  + D  K   +++  + +   +   +L     D+ Q     L  
Sbjct: 1252 LTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL-----DMKQRTIQQLKE 1306

Query: 192  QANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPI-RLT 250
            Q N Q  E        + +    +  I+   ++ ++E+      +   +  K + + RL 
Sbjct: 1307 QLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLA 1366

Query: 251  ADLSAETLQARREWRPIFNILKEKNFQ 277
             +L         +W+   N L+ KN Q
Sbjct: 1367 TEL--------EKWKEKCNDLETKNNQ 1385


>gi|149363685 hypothetical protein LOC23379 [Homo sapiens]
          Length = 2266

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 33/159 (20%), Positives = 70/159 (44%), Gaps = 24/159 (15%)

Query: 50  SNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARE---------- 99
           + Y +  +++Q   ++  N    +EE + +I+  +KC +EL  LK +  E          
Sbjct: 52  TEYQKKCDELQFARRENSNLHHQVEEMLQKISPLQKCQEELGSLKAELEEKKSSLKLYQD 111

Query: 100 -------LREEC-------RSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQS 145
                  ++EEC       + L ++  +L+E       +  +++ E K+ EK  K+ ++ 
Sbjct: 112 THQEYARVKEECLKSDAQKKKLEAKVKKLQEAAVKQTQDFKQLRNEKKILEKEFKKTQER 171

Query: 146 LQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQE 184
           L E         LR IG   S +  G+  +  ++ +++E
Sbjct: 172 LDEFSKQKNEKELRHIGTQISSDSYGSIDKRKVKLLLKE 210


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 55/281 (19%), Positives = 124/281 (44%), Gaps = 27/281 (9%)

Query: 52   YSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRC 111
            Y+E + +++    + ++  K++    T     EK  KE++ LK+   EL+++   L+ +C
Sbjct: 762  YTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKC 821

Query: 112  DQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENG 171
             + +E++ A+  E   +K+    +   +K +E+    + D + + N  L+ V +  E+  
Sbjct: 822  GEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDIN 881

Query: 172  TKLE--NTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEK 229
             +        +I++ N  N   Q   +   +     + SS   + R       KV+    
Sbjct: 882  QEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMR-------KVQDSNA 934

Query: 230  MLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFI 289
             + A   KG+  +    + L A++ A+    ++E   I   +K       + YA  +SF 
Sbjct: 935  EILANYRKGQEEI----VTLHAEIKAQ----KKELDTIQECIK-------VKYAPIVSF- 978

Query: 290  SEGEIKYFIDKQMLRDFVTTRPALQELLKEAL--NMERNNR 328
             E E K+   ++ L+D ++ +     + +E +  N + N++
Sbjct: 979  EECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDK 1019



 Score = 35.4 bits (80), Expect = 0.073
 Identities = 56/288 (19%), Positives = 124/288 (43%), Gaps = 47/288 (16%)

Query: 50   SNYSELREDIQTKGKKVENFEKNLE---ECI----TRITNTEKCLKELMELKTKARELRE 102
            +NY + +E+I T   +++  +K L+   ECI      I + E+C     E K KA E   
Sbjct: 938  ANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEEC-----ERKFKATE--- 989

Query: 103  ECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPN-LRLI 161
              + L+ +  +  ++ S  E+E+ + KQE    +K I   ++ L++    +++ + +   
Sbjct: 990  --KELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERA 1047

Query: 162  GVPESDEENG---------TKLENTLQDIIQEN---------FPNLARQANIQIQEIQRM 203
               ++DE N          T+++N  + +++EN           NL ++ ++ +++++ +
Sbjct: 1048 LSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEAL 1107

Query: 204  SQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLS---AETLQA 260
             +  +          +   K E+K       +E+  VT   + +    + S   AE LQ 
Sbjct: 1108 KKSLNG--------TIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQI 1159

Query: 261  RREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVT 308
            +  +     I+K    +       K+  +S+ + +    KQ L+   T
Sbjct: 1160 KEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLET 1207



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 34/181 (18%), Positives = 81/181 (44%), Gaps = 18/181 (9%)

Query: 83  TEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRI--- 139
           TE+   +L +LK K      E   LR++  Q E  V   + +  ++ +E K  +K +   
Sbjct: 526 TEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMC 585

Query: 140 ----KRNEQSLQEIWDYVKRPNLRL-IGVPESDEENGTKLENTLQDIIQENFPNLA---R 191
               ++  + + E+    K  + +L + +P    EN   ++++L + + E    L    R
Sbjct: 586 EMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFEN---MKSSLSNEVNEKAKKLVEMER 642

Query: 192 QANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGR----VTLKGKPI 247
           +    + EI+++ +   + +A     +      ++K ++ + + E G+    +TLK + +
Sbjct: 643 EHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTL 702

Query: 248 R 248
           +
Sbjct: 703 Q 703



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 12/92 (13%)

Query: 54  ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
           EL    QT   + E  +K LE      T  E   ++ ++L+ +      EC++L   C++
Sbjct: 414 ELSLPSQTSYSENEILKKELE---AMRTFCESAKQDRLKLQNELAHKVAECKALALECER 470

Query: 114 L----EERVSAMEDEMNEMKQ-----EGKVRE 136
           +    +E++  +ED + ++++     EGKV++
Sbjct: 471 VKEDSDEQIKQLEDALKDVQKRMYESEGKVKQ 502


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 55/281 (19%), Positives = 124/281 (44%), Gaps = 27/281 (9%)

Query: 52   YSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRC 111
            Y+E + +++    + ++  K++    T     EK  KE++ LK+   EL+++   L+ +C
Sbjct: 775  YTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKC 834

Query: 112  DQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENG 171
             + +E++ A+  E   +K+    +   +K +E+    + D + + N  L+ V +  E+  
Sbjct: 835  GEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDIN 894

Query: 172  TKLE--NTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEK 229
             +        +I++ N  N   Q   +   +     + SS   + R       KV+    
Sbjct: 895  QEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMR-------KVQDSNA 947

Query: 230  MLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFI 289
             + A   KG+  +    + L A++ A+    ++E   I   +K       + YA  +SF 
Sbjct: 948  EILANYRKGQEEI----VTLHAEIKAQ----KKELDTIQECIK-------VKYAPIVSF- 991

Query: 290  SEGEIKYFIDKQMLRDFVTTRPALQELLKEAL--NMERNNR 328
             E E K+   ++ L+D ++ +     + +E +  N + N++
Sbjct: 992  EECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDK 1032



 Score = 35.4 bits (80), Expect = 0.073
 Identities = 56/288 (19%), Positives = 124/288 (43%), Gaps = 47/288 (16%)

Query: 50   SNYSELREDIQTKGKKVENFEKNLE---ECI----TRITNTEKCLKELMELKTKARELRE 102
            +NY + +E+I T   +++  +K L+   ECI      I + E+C     E K KA E   
Sbjct: 951  ANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEEC-----ERKFKATE--- 1002

Query: 103  ECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPN-LRLI 161
              + L+ +  +  ++ S  E+E+ + KQE    +K I   ++ L++    +++ + +   
Sbjct: 1003 --KELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERA 1060

Query: 162  GVPESDEENG---------TKLENTLQDIIQEN---------FPNLARQANIQIQEIQRM 203
               ++DE N          T+++N  + +++EN           NL ++ ++ +++++ +
Sbjct: 1061 LSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEAL 1120

Query: 204  SQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLS---AETLQA 260
             +  +          +   K E+K       +E+  VT   + +    + S   AE LQ 
Sbjct: 1121 KKSLNG--------TIENLKEELKSMQRCYEKEQQTVTKLHQLLENQKNSSVPLAEHLQI 1172

Query: 261  RREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVT 308
            +  +     I+K    +       K+  +S+ + +    KQ L+   T
Sbjct: 1173 KEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLET 1220



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 34/181 (18%), Positives = 81/181 (44%), Gaps = 18/181 (9%)

Query: 83  TEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRI--- 139
           TE+   +L +LK K      E   LR++  Q E  V   + +  ++ +E K  +K +   
Sbjct: 539 TEELKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMC 598

Query: 140 ----KRNEQSLQEIWDYVKRPNLRL-IGVPESDEENGTKLENTLQDIIQENFPNLA---R 191
               ++  + + E+    K  + +L + +P    EN   ++++L + + E    L    R
Sbjct: 599 EMEREKKGRKVTEMEGQAKELSAKLALSIPAEKFEN---MKSSLSNEVNEKAKKLVEMER 655

Query: 192 QANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGR----VTLKGKPI 247
           +    + EI+++ +   + +A     +      ++K ++ + + E G+    +TLK + +
Sbjct: 656 EHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTL 715

Query: 248 R 248
           +
Sbjct: 716 Q 716



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 22/92 (23%), Positives = 46/92 (50%), Gaps = 12/92 (13%)

Query: 54  ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
           EL    QT   + E  +K LE      T  E   ++ ++L+ +      EC++L   C++
Sbjct: 427 ELSLPSQTSYSENEILKKELE---AMRTFCESAKQDRLKLQNELAHKVAECKALALECER 483

Query: 114 L----EERVSAMEDEMNEMKQ-----EGKVRE 136
           +    +E++  +ED + ++++     EGKV++
Sbjct: 484 VKEDSDEQIKQLEDALKDVQKRMYESEGKVKQ 515


>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
          Length = 1710

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 53/251 (21%), Positives = 111/251 (44%), Gaps = 28/251 (11%)

Query: 30   TEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLE----ECITRITNTEK 85
            T +   E +  E    G  +++  E+   I     K+++    LE    +C+   T  + 
Sbjct: 1370 TRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQI 1429

Query: 86   CLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEM-NEMKQEGKVREKRIKRNEQ 144
              +EL+ +KT    ++++C  L+    +LE+ V  +   +   M + G+V++ + +  E+
Sbjct: 1430 LQEELLSMKT----VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEER 1485

Query: 145  SLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMS 204
            + QEI + +K  NL L     S E         L+   + NF ++  Q  ++I++++   
Sbjct: 1486 ARQEIAEKLKEVNLFLQAQAASQE--------NLEQFRENNFASMKSQMELRIKDLESEL 1537

Query: 205  QRYSSRRATPRHIIVRFTKVEM-KEKMLRAAREKGRVTLKGKPIRLT---ADLSAETLQA 260
             +  + +         F K E+ K K L     K R +L  K  +     A+++ + L  
Sbjct: 1538 SKIKTSQED-------FNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVE 1590

Query: 261  RREWRPIFNIL 271
            +++ R +F  L
Sbjct: 1591 KQQSRSLFTTL 1601



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 39/182 (21%), Positives = 77/182 (42%), Gaps = 13/182 (7%)

Query: 55   LREDIQTKGKKVENFEK---NLEECITRITNT--EKCLKELMELKTKARELREECRSLRS 109
            LR+ +     K +N EK   N+++    I      +  K+ + L+ + +EL  EC  L+ 
Sbjct: 1146 LRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKE 1205

Query: 110  RCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEE 169
            R  Q E   +  E  + +++QE     K+   +E SL    +   R  + L    +  ++
Sbjct: 1206 RQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASL----EVTSRYRINLEDETQDLKK 1261

Query: 170  NGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEK 229
               ++ N LQ+  Q+      R A       Q++ +  +  + T +    +  K+E  +K
Sbjct: 1262 KLGQIRNQLQE-AQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKK---QMDKIEELQK 1317

Query: 230  ML 231
             L
Sbjct: 1318 NL 1319



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 28/146 (19%), Positives = 59/146 (40%), Gaps = 8/146 (5%)

Query: 36   ENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKT 95
            E  +    E   R     +L++++    KK    E +LE       N E    E  +LK 
Sbjct: 1205 ERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLED---ETQDLKK 1261

Query: 96   KARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKR 155
            K  ++R + +  + R  +       M+D   +++++    +  +K+    ++E+     +
Sbjct: 1262 KLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEEL-----Q 1316

Query: 156  PNLRLIGVPESDEENGTKLENTLQDI 181
             NL    + E ++E   KL    Q +
Sbjct: 1317 KNLLNANLSEDEKEQLKKLMELKQSL 1342



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 31/158 (19%), Positives = 68/158 (43%), Gaps = 22/158 (13%)

Query: 41  ELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELME-LKTKARE 99
           ELR      +   + R D Q +  + +N     +  +T   + +K ++   + + ++   
Sbjct: 843 ELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSH 902

Query: 100 LREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKR------------------IKR 141
             EE + L  +   L+E ++ +  E++ +K + + +EK+                  IK+
Sbjct: 903 SHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQ 962

Query: 142 NEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQ 179
           NE++L +    + + N RL  +   +    +KLEN  Q
Sbjct: 963 NEETLTQT---ISQYNGRLSVLTAENAMLNSKLENEKQ 997


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 51/288 (17%), Positives = 125/288 (43%), Gaps = 22/288 (7%)

Query: 35  MENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELK 94
           ME+  ++L+EA  +      L+     + K ++NF   L+    ++ + +   K   E K
Sbjct: 682 MEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGK 741

Query: 95  TKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVK 154
           ++ ++LR++  +   +   LE   +A   + + + +E + RE ++   +++L E+    +
Sbjct: 742 SEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKE 801

Query: 155 RPNLRLIGVPE---SDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRR 211
                L  + E      E    ++ ++Q+ + +       Q N+   +++++ +  +   
Sbjct: 802 TLEKELQILKEKFAEASEEAVSVQRSMQETVNK-LHQKEEQFNMLSSDLEKLRENLADME 860

Query: 212 ATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNIL 271
           A       +F + + +E+ L  A+EK    +  + ++++ D S++  +   E R     L
Sbjct: 861 A-------KFREKDEREEQLIKAKEKLENDI-AEIMKMSGDNSSQLTKMNDELR-----L 907

Query: 272 KEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKE 319
           KE++ +       +L      E   F+ K +    V    + QE  K+
Sbjct: 908 KERDVE-----ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKK 950



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)

Query: 35   MENDFDELREAGFRR-SNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMEL 93
            ++N+ D L+E   +     ++ +E +  + +K+E F K +E          + L  L E 
Sbjct: 1073 LQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEE 1132

Query: 94   KTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQE 148
              K  E     R   +   +LEE  S + +++ EMK+      K     + SLQ+
Sbjct: 1133 NVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQK 1187


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 51/288 (17%), Positives = 125/288 (43%), Gaps = 22/288 (7%)

Query: 35  MENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELK 94
           ME+  ++L+EA  +      L+     + K ++NF   L+    ++ + +   K   E K
Sbjct: 717 MEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGK 776

Query: 95  TKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVK 154
           ++ ++LR++  +   +   LE   +A   + + + +E + RE ++   +++L E+    +
Sbjct: 777 SEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKE 836

Query: 155 RPNLRLIGVPE---SDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRR 211
                L  + E      E    ++ ++Q+ + +       Q N+   +++++ +  +   
Sbjct: 837 TLEKELQILKEKFAEASEEAVSVQRSMQETVNK-LHQKEEQFNMLSSDLEKLRENLADME 895

Query: 212 ATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNIL 271
           A       +F + + +E+ L  A+EK    +  + ++++ D S++  +   E R     L
Sbjct: 896 A-------KFREKDEREEQLIKAKEKLENDI-AEIMKMSGDNSSQLTKMNDELR-----L 942

Query: 272 KEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKE 319
           KE++ +       +L      E   F+ K +    V    + QE  K+
Sbjct: 943 KERDVE-----ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKK 985



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 1/115 (0%)

Query: 35   MENDFDELREAGFRR-SNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMEL 93
            ++N+ D L+E   +     ++ +E +  + +K+E F K +E          + L  L E 
Sbjct: 1108 LQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEE 1167

Query: 94   KTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQE 148
              K  E     R   +   +LEE  S + +++ EMK+      K     + SLQ+
Sbjct: 1168 NVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQK 1222



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 41/184 (22%), Positives = 76/184 (41%), Gaps = 25/184 (13%)

Query: 31  EQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRI-TNTEKCLKE 89
           EQ   E D  E  E     S+  E+ +++       +     LE  + ++ T  E   +E
Sbjct: 365 EQLLAERDL-ERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADRE 423

Query: 90  LMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEI 149
            +EL     +L EE R +    + L+ RV        +++ + K+   RIK  EQSL  +
Sbjct: 424 KVEL---LNQLEEEKRKV----EDLQFRVEEESITKGDLETQTKLEHARIKELEQSL--L 474

Query: 150 WDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQE--NFPNLARQANIQIQEIQRMSQRY 207
           ++  K   L+             +LE+T    + E      L +   +++QE+  + +R 
Sbjct: 475 FEKTKADKLQ------------RELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRL 522

Query: 208 SSRR 211
            S +
Sbjct: 523 ESNK 526


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 63/299 (21%), Positives = 127/299 (42%), Gaps = 24/299 (8%)

Query: 26   SSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEK 85
            + P  +   +  +  + +E    +   + LR  +  + KK  + E+       +I   E+
Sbjct: 1282 TKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEE 1341

Query: 86   CLKELMELKTKARELR-EECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKR------ 138
             L  + E   +   +R EE   LR+      E +     ++++++ E +  ++R      
Sbjct: 1342 ELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELER 1401

Query: 139  ----IKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQ-- 192
                ++R  Q+ +E    V+R   RL  + + + E   K+ +T + ++Q++ P  AR+  
Sbjct: 1402 QLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQD-PQQAREHA 1460

Query: 193  -ANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAR---EKGRVTLKGKPIR 248
               +Q++E Q   Q       T R  +    K E+KEK++ +     EKG    + +  R
Sbjct: 1461 LLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQ--R 1518

Query: 249  LTADLSAETLQARR---EWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLR 304
            L + L  E+   R    E   +   L E  F    S + +L F+ E   K  +++Q L+
Sbjct: 1519 LKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKS-SKELDFLREENHKLQLERQNLQ 1576



 Score = 35.0 bits (79), Expect = 0.096
 Identities = 29/137 (21%), Positives = 63/137 (45%), Gaps = 12/137 (8%)

Query: 78  TRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNE---MKQEGKV 134
           TR+ +T +  + L++L   A+E  +    L     Q  E ++  E+ +N+   + +  +V
Sbjct: 588 TRVEDTNRKYEHLLQLLDLAQEKVDVANRLEKSLQQSWELLATHENHLNQDDTVPESSRV 647

Query: 135 REKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQAN 194
            + + +       E+     +    L+G  E + +   +  +TL    QE+ P+L RQ  
Sbjct: 648 LDSKGQELAAMACEL-----QAQKSLLGEVEQNLQAAKQCSSTLASRFQEHCPDLERQE- 701

Query: 195 IQIQEIQRMSQRYSSRR 211
               E+ ++ QR+++ R
Sbjct: 702 ---AEVHKLGQRFNNLR 715



 Score = 35.0 bits (79), Expect = 0.096
 Identities = 64/308 (20%), Positives = 126/308 (40%), Gaps = 47/308 (15%)

Query: 35   MENDFDELREAGFRRSNYSELRED----IQTKGKKVENFEKNLEECIT--RITNTEKCLK 88
            +E ++ +L+E   R+    E +E+    +Q K K++E      E  IT   +   EK   
Sbjct: 1066 LEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAA 1125

Query: 89   ELMELKTKARELREECRSLRS---RCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQS 145
               E+    R+  +E    R+      +L  ++ A+E+E  ++  + KVRE  ++ + ++
Sbjct: 1126 TEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVRE-IVRPDPKA 1184

Query: 146  LQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQ 205
              E+       NLRL  V +  +  G   E  L+    E      R   ++++E+ +   
Sbjct: 1185 ESEV------ANLRLELVEQERKYRGA--EEQLRSYQSELEALRRRGPQVEVKEVTKEVI 1236

Query: 206  RYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWR 265
            +Y              T  EM++++ R   E    T      RL      E  Q ++E +
Sbjct: 1237 KYK-------------TDPEMEKELQRLREEIVDKT------RLIERCDLEIYQLKKEIQ 1277

Query: 266  PIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEALNMER 325
             +      K+ +P++     +  I    +++  D Q   +  + R  L E  K+ +++ER
Sbjct: 1278 AL------KDTKPQVQTKEVVQEI----LQFQEDPQTKEEVASLRAKLSEEQKKQVDLER 1327

Query: 326  NNRYQPLQ 333
                Q  Q
Sbjct: 1328 ERASQEEQ 1335


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 42/220 (19%), Positives = 100/220 (45%), Gaps = 25/220 (11%)

Query: 40   DELREAGFRRSNYSELR----EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKT 95
            D++++  F+    S+ +    E +     K   ++K  +   T+  NT K L+  +ELK+
Sbjct: 1412 DQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKS 1471

Query: 96   K-ARELREECRSLRSRCDQLEERVSA----MEDEMNEMKQEGKVREKRIKRNEQSLQEIW 150
            K A E  E+   L+   DQ  +R       MED+ ++M+++    E  +K     + E+ 
Sbjct: 1472 KEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELE 1531

Query: 151  DYVKRPNLRLIGVPESDEENGTKLENTLQDIIQ--ENFPNLARQANIQIQE--------- 199
            D++ +  + +  + E  +    + +   ++++Q  ++F  L  + + +++E         
Sbjct: 1532 DHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLE 1591

Query: 200  --IQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREK 237
              +  M     +++    H+ +    V+ KE+ L+A  ++
Sbjct: 1592 NQVYSMKAELETKKKELEHVNL---SVKSKEEELKALEDR 1628



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 48/242 (19%), Positives = 101/242 (41%), Gaps = 34/242 (14%)

Query: 90  LMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEI 149
           L E + K R+L++E  + R+R  +LE   S++E  + E K + K     ++  +      
Sbjct: 548 LTESENKLRDLQQEAETYRTRILELE---SSLEKSLQENKNQSKDLAVHLEAEK------ 598

Query: 150 WDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSS 209
                + N  +  + E  +     L++    +  E    L +Q   ++++++   ++   
Sbjct: 599 ----NKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKE 654

Query: 210 RRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFN 269
                + II +    EM EK L       ++ +K   +   +   +E L+AR +     +
Sbjct: 655 TLLKDKEIIFQAHIEEMNEKTLE------KLDVKQTELESLSSELSEVLKARHKLEEELS 708

Query: 270 ILKEKNFQPRISYAAKL------------SFISEGEIKYFIDKQMLRDFVTTRPALQELL 317
           +LK++  + +    AK+            S I E E+     ++ L+D +     L+ LL
Sbjct: 709 VLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN---QLELLL 765

Query: 318 KE 319
           KE
Sbjct: 766 KE 767



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 61/273 (22%), Positives = 111/273 (40%), Gaps = 31/273 (11%)

Query: 57   EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEE 116
            +  Q  G++ +N  K  EE I  + N    +K   EL+TK +EL     S++S+    EE
Sbjct: 1567 QHFQELGEEKDNRVKEAEEKILTLENQVYSMKA--ELETKKKELEHVNLSVKSK----EE 1620

Query: 117  RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLEN 176
             + A+ED + E +   K+ E + ++ EQ +  I         +L+   E  EE   K   
Sbjct: 1621 ELKALEDRL-ESESAAKLAELK-RKAEQKIAAI-------KKQLLSQMEEKEEQYKKGTE 1671

Query: 177  TLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAARE 236
            +    +        R+ +I  ++++ +    S     PR         E +E   +   +
Sbjct: 1672 SHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQ 1731

Query: 237  KGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAAKLSFISEGEIKY 296
            K   T + K   L  +L+ +    +R  +     +   +F+ R  Y  +L  +   E K 
Sbjct: 1732 K---TYEEKISVLQRNLTEKEKLLQRVGQEKEETV-SSHFEMRCQYQERLIKLEHAEAKQ 1787

Query: 297  FIDKQMLRDFVTTRPALQELLKEALNMERNNRY 329
              D+ M+         LQE L+     E+N +Y
Sbjct: 1788 HEDQSMIGH-------LQEELE-----EKNKKY 1808



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 41/201 (20%), Positives = 92/201 (45%), Gaps = 31/201 (15%)

Query: 88   KELMELKTKARELREECRSLRSR----CDQLEERVSAMEDEMNEMKQEGKVREKRIKRNE 143
            ++L++L+T+   L ++   + ++    C +L+     ++D M +++++    E+++K   
Sbjct: 826  QKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK--- 882

Query: 144  QSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRM 203
             SL +++              ES  E+G K +   + I+ E    + +    Q +EI+ +
Sbjct: 883  -SLTQVY--------------ESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEIL 927

Query: 204  SQRYSSRRATPRHIIVRF-TKVEMKEKMLRAAREKGR---VTLKGKPIRLTADLSAETLQ 259
            +Q+ S++  +   +   + TK + +EK +   ++K +    TLK K +   A L  E   
Sbjct: 928  TQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELEN 987

Query: 260  ARREWRPIFNILKEKNFQPRI 280
               E        KEK F  ++
Sbjct: 988  TALELSQ-----KEKQFNAKM 1003



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 32/145 (22%), Positives = 70/145 (48%), Gaps = 16/145 (11%)

Query: 36  ENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKT 95
           + + ++LRE         E  ++   K K++  F+ ++EE        EK L++L   +T
Sbjct: 639 QTEMEKLREK-------CEQEKETLLKDKEII-FQAHIEEM------NEKTLEKLDVKQT 684

Query: 96  KARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKR 155
           +   L  E   +     +LEE +S ++D+ ++MKQE + +    K + Q  Q++   +K 
Sbjct: 685 ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQ--QQVDSIIKE 742

Query: 156 PNLRLIGVPESDEENGTKLENTLQD 180
             + +    ++ ++   +LE  L++
Sbjct: 743 HEVSIQRTEKALKDQINQLELLLKE 767



 Score = 32.0 bits (71), Expect = 0.81
 Identities = 50/258 (19%), Positives = 110/258 (42%), Gaps = 18/258 (6%)

Query: 71  KNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQ 130
           K LE    R+   E  LK   E     +  +E+C  L S  + L+E++     E+ ++K 
Sbjct: 279 KTLETLQQRVKRQENLLKRCKET---IQSHKEQCTLLTSEKEALQEQLDERLQELEKIKD 335

Query: 131 EGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLA 190
                + ++    +  + + + +++    +I   E+  +    LE   ++I Q    +  
Sbjct: 336 LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIA--ETKRQMHETLEMKEEEIAQ--LRSRI 391

Query: 191 RQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLT 250
           +Q   Q +E++   Q+  S RA    +    +  +  E+  R  + K  +  + K I  T
Sbjct: 392 KQMTTQGEELR--EQKEKSERAAFEELEKALSTAQKTEEARR--KLKAEMDEQIKTIEKT 447

Query: 251 ADLSAETLQAR--REWRPIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVT 308
           ++    +LQ    R  + + +++K+ + +      AKL  + E E+    ++++ +   T
Sbjct: 448 SEEERISLQQELSRVKQEVVDVMKKSSEE----QIAKLQKLHEKELAR-KEQELTKKLQT 502

Query: 309 TRPALQELLKEALNMERN 326
                QE +K AL   ++
Sbjct: 503 REREFQEQMKVALEKSQS 520



 Score = 29.3 bits (64), Expect = 5.2
 Identities = 22/115 (19%), Positives = 51/115 (44%), Gaps = 5/115 (4%)

Query: 31   EQSWMENDFDELREAGFRR-SNYSELREDIQTKGKKVENFEKNLEECITRITNTE----K 85
            E+  M  +   L+E G ++ +  +EL+E ++ K   V +  ++  +    +   E    K
Sbjct: 1086 EKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNK 1145

Query: 86   CLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIK 140
             LKE   L+ +  EL+      + +  +L  ++   ++E   +K   +   K ++
Sbjct: 1146 SLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1200


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 48/237 (20%), Positives = 107/237 (45%), Gaps = 7/237 (2%)

Query: 92   ELKTKARE---LREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQE 148
            E+K+ A+E   L+     L+S  DQL+E +  +  +  E ++E KV    +K  E+++ E
Sbjct: 1436 EMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINE 1495

Query: 149  IWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYS 208
            +   +      +  + +  E    KL+N +Q+I ++      +Q +   +++  + Q   
Sbjct: 1496 LRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKE 1555

Query: 209  SRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKP--IRLTADLSAETLQARREWRP 266
             R+A    +    +K+      L+ ++E+ ++ +K K    R+   L  E  Q +   + 
Sbjct: 1556 HRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKE 1615

Query: 267  IFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEALNM 323
            I  + K K  Q +     K++ ++E + K    + +   F T +  L+ +  E + +
Sbjct: 1616 I--VAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRL 1670



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 47/240 (19%), Positives = 104/240 (43%), Gaps = 29/240 (12%)

Query: 22   KECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRIT 81
            + C      E+   E    +L+E   +  N  E   ++Q K  ++EN +  L+     + 
Sbjct: 1117 RTCDRLAEVEEKLKEKS-QQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1175

Query: 82   NTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEM------------- 128
            + E    E +EL  K  E  EE +S+      L+E   + E E + +             
Sbjct: 1176 HMET---ERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQ 1232

Query: 129  -KQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDI--IQEN 185
             K+E K+    +K +++++ E+   V     ++I   +  E++ TKL+  +  +   QE 
Sbjct: 1233 TKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDL-EKSHTKLQEEIPVLHEEQEL 1291

Query: 186  FPNLARQANIQ--IQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLK 243
             PN+   +  Q  + E++ ++++ +++ +T         ++EM+   L    ++ +  +K
Sbjct: 1292 LPNVKEVSETQETMNELELLTEQSTTKDST------TLARIEMERLRLNEKFQESQEEIK 1345



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 34/216 (15%), Positives = 101/216 (46%), Gaps = 21/216 (9%)

Query: 40   DELREAGFRRSNYSELREDIQTKGKKVENFEKNLEEC-----------ITRITNTEKCLK 88
            ++++E          L++D+    KKV   E+  ++            I  +   +K  +
Sbjct: 1820 EKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHE 1879

Query: 89   ELMELKTKARE---LREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQS 145
             L E+K+  +E   LR    +L+   DQL+E +   +    E++QE K      K ++++
Sbjct: 1880 NLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKET 1939

Query: 146  LQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANI-----QIQEI 200
            + ++ + +    +++  + +  +++  +L+  +Q++ ++    L  + ++     +I E+
Sbjct: 1940 VDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEM 1999

Query: 201  QRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAARE 236
            +++ +++ ++  + +   VR    ++ +K+  +  E
Sbjct: 2000 EQLKKQFEAQNLSMQS--VRMDNFQLTKKLHESLEE 2033



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 59/277 (21%), Positives = 123/277 (44%), Gaps = 23/277 (8%)

Query: 55   LREDIQTKGKKVENFE-KNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
            L+E  +T+   +EN E +N+   +T+I +    L+E+  +  +  +LR    +L+   DQ
Sbjct: 1649 LKEQFETQKLNLENIETENIR--LTQILHEN--LEEMRSVTKERDDLRSVEETLKVERDQ 1704

Query: 114  LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTK 173
            L+E +        E ++E K+    +K +++++ ++   V      +  + +  E +   
Sbjct: 1705 LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA 1764

Query: 174  LENTLQDI-IQENFPNLARQANIQIQEIQR--------MSQRYSSRRATPRHIIVRFTKV 224
            L+   QD+ IQE      R A++ ++E Q         +S++        + +     K+
Sbjct: 1765 LK--AQDLKIQEEL----RIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKL 1818

Query: 225  EMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIFNILKEKNFQPRISYAA 284
            + K + L+ A E   +TLK K +  T    +E  Q +++ +     L +   +  ++ A 
Sbjct: 1819 QEKIQELK-ANEHQLITLK-KDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIE-NLNLAQ 1875

Query: 285  KLSFISEGEIKYFIDKQMLRDFVTTRPALQELLKEAL 321
            KL    E       ++  LR    T    ++ LKE+L
Sbjct: 1876 KLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESL 1912



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 65/353 (18%), Positives = 150/353 (42%), Gaps = 28/353 (7%)

Query: 4    KQSRKTGNSKKQSASPPPKECSSSPATEQSW--MENDFDELREAGFRRSNYSELREDIQT 61
            K+ ++T +  ++S S    +  ++   E+S   ++ +   L E      N  E+ E  +T
Sbjct: 1245 KEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQET 1304

Query: 62   KGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAM 121
              +     E++  +  T +   E    E + L  K +E +EE +SL    D L+    A+
Sbjct: 1305 MNELELLTEQSTTKDSTTLARIEM---ERLRLNEKFQESQEEIKSLTKERDNLKTIKEAL 1361

Query: 122  EDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPN--LRLIGVPESDEENGTKLENT-- 177
            E + +++K+  +    +I+ ++   ++  +  ++ N   +++   E  +   + L     
Sbjct: 1362 EVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEI 1421

Query: 178  ----LQDIIQENFPNLARQANIQ--IQEIQRMSQRYSSR-RATPRHIIVRFTKVEMKEKM 230
                L   +QE+   +   A  +  +Q +Q + Q  S + +   + I+ +  + E + K+
Sbjct: 1422 EMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKV 1481

Query: 231  LRAAREKGRVTLKGKPIRLT-ADLSAETLQARREW--RPIFNILKEKNFQPRISYAAKLS 287
                 ++   T+    + L+  +    T+Q + E     + N ++E   +       ++S
Sbjct: 1482 AHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQIS 1541

Query: 288  FISE--GEIKYFIDKQMLRDFVTTRPALQELLKEALNMERNNRYQPLQNHAKM 338
             + E   E+K F + +  +D      ALQ +  E+  +E  NR Q  Q   ++
Sbjct: 1542 EVQEKVNELKQFKEHRKAKD-----SALQSI--ESKMLELTNRLQESQEEIQI 1587



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 9/113 (7%)

Query: 40  DELREAGFRRSNYSELRE---DIQTKGKKVEN----FEKNLEECITRITNTEKCLKELME 92
           D  RE+ F RS   EL+E   ++ T  K++EN    ++  LE       + EK L+    
Sbjct: 636 DAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFN 695

Query: 93  LKTKARELREECRSLRSRCD-QLEERVSAMEDEMN-EMKQEGKVREKRIKRNE 143
             TK   L +        C+ +LE +++ ++ E+N E+++   +RE+ I  +E
Sbjct: 696 EITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSE 748



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 25/152 (16%), Positives = 68/152 (44%), Gaps = 6/152 (3%)

Query: 56  REDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLE 115
           ++D+ T     ++ ++  +   T   + E+  K ++E   +   + +E  +L     + +
Sbjct: 802 KDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLE---ENERMNQEIVNLSKEAQKFD 858

Query: 116 ERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLE 175
             + A++ E++   QE + + + ++     ++++ + ++  +  L  V         KL+
Sbjct: 859 SSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQ 918

Query: 176 NTLQDI---IQENFPNLARQANIQIQEIQRMS 204
            TL+++    QE       Q ++QI+  Q  S
Sbjct: 919 QTLEEVKTLTQEKDDLKQLQESLQIERDQLKS 950



 Score = 28.9 bits (63), Expect = 6.8
 Identities = 19/110 (17%), Positives = 59/110 (53%), Gaps = 5/110 (4%)

Query: 35   MENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELK 94
            ++N   E+ E    + N  ++ E +Q K  +++ F+++ +   + + + E    +++EL 
Sbjct: 1521 LQNKIQEIYEKE-EQFNIKQISE-VQEKVNELKQFKEHRKAKDSALQSIES---KMLELT 1575

Query: 95   TKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQ 144
             + +E +EE + +    ++++    A++ E +++K+  K    ++K +++
Sbjct: 1576 NRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQE 1625


>gi|214010216 SMC6 protein [Homo sapiens]
          Length = 1091

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 46/238 (19%), Positives = 102/238 (42%), Gaps = 26/238 (10%)

Query: 26  SSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEK 85
           SS  T   ++  D D         S  S+L  +++ K  ++ N +++L      I + E+
Sbjct: 651 SSENTRPKFLSRDVD---------SEISDLENEVENKTAQILNLQQHLSALEKDIKHNEE 701

Query: 86  CLKELM----ELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKR 141
            LK       ELK K R+   E R L +  +     ++ +EDE  E K + K+ E+ +++
Sbjct: 702 LLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQ 761

Query: 142 NEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQ 201
            +++++         +L+ + +   ++ +  K +      + +   +    A+ ++   +
Sbjct: 762 QKENME---------HLKSLKIEAENKYDAIKFKINQLSELADPLKDELNLADSEVDNQK 812

Query: 202 RMSQRYSSRRATPRHII-VRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETL 258
           R  + Y  ++      +  +  +++MKEK L     + R      P R+  + SA  L
Sbjct: 813 RGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQIC---PERIEVEKSASIL 867


>gi|13375848 SMC6 protein [Homo sapiens]
          Length = 1091

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 46/238 (19%), Positives = 102/238 (42%), Gaps = 26/238 (10%)

Query: 26  SSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEK 85
           SS  T   ++  D D         S  S+L  +++ K  ++ N +++L      I + E+
Sbjct: 651 SSENTRPKFLSRDVD---------SEISDLENEVENKTAQILNLQQHLSALEKDIKHNEE 701

Query: 86  CLKELM----ELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKR 141
            LK       ELK K R+   E R L +  +     ++ +EDE  E K + K+ E+ +++
Sbjct: 702 LLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQ 761

Query: 142 NEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQ 201
            +++++         +L+ + +   ++ +  K +      + +   +    A+ ++   +
Sbjct: 762 QKENME---------HLKSLKIEAENKYDAIKFKINQLSELADPLKDELNLADSEVDNQK 812

Query: 202 RMSQRYSSRRATPRHII-VRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETL 258
           R  + Y  ++      +  +  +++MKEK L     + R      P R+  + SA  L
Sbjct: 813 RGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQIC---PERIEVEKSASIL 867


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 64/301 (21%), Positives = 128/301 (42%), Gaps = 38/301 (12%)

Query: 31   EQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKEL 90
            E S  + + D+L+E         +   ++Q   + VE   KN+E   +R +NT +  +  
Sbjct: 770  EVSSHDQEMDKLKE---------QYDAELQALRESVEEATKNVEVLASR-SNTSEQDQAG 819

Query: 91   MELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMK-QEGKVRE--KRIKRNEQSLQ 147
             E++ K   L+EE   L+ R ++LE RV+ ++ ++ ++K  E K +E  K+ +   + L+
Sbjct: 820  TEMRVKL--LQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLE 877

Query: 148  EIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQE--NFPNLARQANIQIQEIQRMSQ 205
            E   + ++     +    + E      +  L    QE        ++ + Q ++++R+  
Sbjct: 878  EALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN 937

Query: 206  RYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWR 265
               + R      I +  K EM + ++ A+R           + L   L     + RRE  
Sbjct: 938  EMENERWHLGKTIEKLQK-EMAD-IVEASRT--------STLELQNQLDEYKEKNRRELA 987

Query: 266  PIFNILKEKNFQPRISYAAKLSFISEGEIKYFIDKQMLRDF-------VTTRPALQELLK 318
             +   LKEK  +   S    +    E  +     ++ LRD+       +T R  L++ LK
Sbjct: 988  EMQRQLKEKTLEAEKSRLTAMKMQDEMRLM----EEELRDYQRAQDEALTKRQLLEQTLK 1043

Query: 319  E 319
            +
Sbjct: 1044 D 1044



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 45/211 (21%), Positives = 93/211 (44%), Gaps = 24/211 (11%)

Query: 31  EQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFE----KNLEECITRITNTEKC 86
           E+  M  + +ELR      S ++E  E+  T  +++E  E    KNLEE        E+ 
Sbjct: 643 ERERMRANLEELR------SQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696

Query: 87  LKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSL 146
             E+ +L+ +  E+ +E  S +   D+      A+ +E+ + KQ+  +++  I + EQ  
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDR---EKGALIEELLQAKQD--LQDLLIAKEEQE- 750

Query: 147 QEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQR 206
               D +++    L  +  + +E  +  +  + D ++E +    +     ++E  +  + 
Sbjct: 751 ----DLLRKRERELTALKGALKEEVSSHDQEM-DKLKEQYDAELQALRESVEEATKNVEV 805

Query: 207 YSSRRATPRHIIVRFTKVEMKEKMLRAAREK 237
            +SR  T           EM+ K+L+   EK
Sbjct: 806 LASRSNTSEQ---DQAGTEMRVKLLQEENEK 833



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 8/94 (8%)

Query: 66   VENFEKNLEECITRITNTEKCLKELM----ELKTKAREL----REECRSLRSRCDQLEER 117
            V   E  + E   R+ + E+    L      L+ K +EL     +E  SL  + DQL  R
Sbjct: 1148 VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLR 1207

Query: 118  VSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWD 151
            + AM+ ++ E ++E    E   K+ ++ L+E  D
Sbjct: 1208 LKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMD 1241


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 41/222 (18%), Positives = 102/222 (45%), Gaps = 30/222 (13%)

Query: 30  TEQSWMENDFDELREAGFRRSNYS----ELREDIQTKGKKVENFEKNLEECITRITNTEK 85
           TE S +  +  +L+     + +++    EL++ I  K  K+++ E+ LE  + ++ N EK
Sbjct: 770 TENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEK 829

Query: 86  CLKEL-MELKTKAREL------REECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKR 138
            +++L  E+K    E+      + +  S+ S+  +L+  +   E++MN MK   + +EK 
Sbjct: 830 TVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKD 889

Query: 139 IKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQ 198
           +    + LQ++                  +E    L+  +Q++ Q N    +  +  +  
Sbjct: 890 LANTGKWLQDL------------------QEENESLKAHVQEVAQHNLKEASSASQFEEL 931

Query: 199 EIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
           EI  + ++ +  +     +  R + +  K ++L+  +++ ++
Sbjct: 932 EIV-LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKL 972



 Score = 35.4 bits (80), Expect = 0.073
 Identities = 44/185 (23%), Positives = 87/185 (47%), Gaps = 22/185 (11%)

Query: 54  ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
           EL + I  K K+++  E +L     R+T+ E+ LK++  +      L+ E + L++    
Sbjct: 604 ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL---LKAEVQKLQA---- 656

Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQ-EIWDYVKRPNLRLIGVPESDEENGT 172
           L    +A   E+ +M+Q   V++ +I+  E+ LQ EI +  K    +++    +D+    
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISN--KMEEFKIL----NDQNKAL 710

Query: 173 KLE-NTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHII-VRFTKVEMKEKM 230
           K E   LQ ++ E  PN        ++++++  Q    +  T   ++     +V  KE+ 
Sbjct: 711 KSEVQKLQTLVSEQ-PN-----KDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEE 764

Query: 231 LRAAR 235
           L A R
Sbjct: 765 LNAIR 769



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 18/93 (19%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 57   EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEE 116
            E ++++ K +EN  +  E     +   EK   E     T+ REL++    L+ + D    
Sbjct: 1190 ERLRSENKDIENLRREREHLEMEL---EKAEMERSTYVTEVRELKDLLTELQKKLDDSYS 1246

Query: 117  RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEI 149
                  +E+N +K +      +++  +   Q++
Sbjct: 1247 EAVRQNEELNLLKAQLNETLTKLRTEQNERQKV 1279


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 41/222 (18%), Positives = 102/222 (45%), Gaps = 30/222 (13%)

Query: 30  TEQSWMENDFDELREAGFRRSNYS----ELREDIQTKGKKVENFEKNLEECITRITNTEK 85
           TE S +  +  +L+     + +++    EL++ I  K  K+++ E+ LE  + ++ N EK
Sbjct: 770 TENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEK 829

Query: 86  CLKEL-MELKTKAREL------REECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKR 138
            +++L  E+K    E+      + +  S+ S+  +L+  +   E++MN MK   + +EK 
Sbjct: 830 TVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKD 889

Query: 139 IKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQ 198
           +    + LQ++                  +E    L+  +Q++ Q N    +  +  +  
Sbjct: 890 LANTGKWLQDL------------------QEENESLKAHVQEVAQHNLKEASSASQFEEL 931

Query: 199 EIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
           EI  + ++ +  +     +  R + +  K ++L+  +++ ++
Sbjct: 932 EIV-LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKL 972



 Score = 35.4 bits (80), Expect = 0.073
 Identities = 44/185 (23%), Positives = 87/185 (47%), Gaps = 22/185 (11%)

Query: 54  ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
           EL + I  K K+++  E +L     R+T+ E+ LK++  +      L+ E + L++    
Sbjct: 604 ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL---LKAEVQKLQA---- 656

Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQ-EIWDYVKRPNLRLIGVPESDEENGT 172
           L    +A   E+ +M+Q   V++ +I+  E+ LQ EI +  K    +++    +D+    
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISN--KMEEFKIL----NDQNKAL 710

Query: 173 KLE-NTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHII-VRFTKVEMKEKM 230
           K E   LQ ++ E  PN        ++++++  Q    +  T   ++     +V  KE+ 
Sbjct: 711 KSEVQKLQTLVSEQ-PN-----KDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEE 764

Query: 231 LRAAR 235
           L A R
Sbjct: 765 LNAIR 769


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 41/222 (18%), Positives = 102/222 (45%), Gaps = 30/222 (13%)

Query: 30  TEQSWMENDFDELREAGFRRSNYS----ELREDIQTKGKKVENFEKNLEECITRITNTEK 85
           TE S +  +  +L+     + +++    EL++ I  K  K+++ E+ LE  + ++ N EK
Sbjct: 770 TENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEK 829

Query: 86  CLKEL-MELKTKAREL------REECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKR 138
            +++L  E+K    E+      + +  S+ S+  +L+  +   E++MN MK   + +EK 
Sbjct: 830 TVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKD 889

Query: 139 IKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQ 198
           +    + LQ++                  +E    L+  +Q++ Q N    +  +  +  
Sbjct: 890 LANTGKWLQDL------------------QEENESLKAHVQEVAQHNLKEASSASQFEEL 931

Query: 199 EIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGRV 240
           EI  + ++ +  +     +  R + +  K ++L+  +++ ++
Sbjct: 932 EIV-LKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKL 972



 Score = 35.4 bits (80), Expect = 0.073
 Identities = 44/185 (23%), Positives = 87/185 (47%), Gaps = 22/185 (11%)

Query: 54  ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
           EL + I  K K+++  E +L     R+T+ E+ LK++  +      L+ E + L++    
Sbjct: 604 ELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL---LKAEVQKLQA---- 656

Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQ-EIWDYVKRPNLRLIGVPESDEENGT 172
           L    +A   E+ +M+Q   V++ +I+  E+ LQ EI +  K    +++    +D+    
Sbjct: 657 LANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISN--KMEEFKIL----NDQNKAL 710

Query: 173 KLE-NTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHII-VRFTKVEMKEKM 230
           K E   LQ ++ E  PN        ++++++  Q    +  T   ++     +V  KE+ 
Sbjct: 711 KSEVQKLQTLVSEQ-PN-----KDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEE 764

Query: 231 LRAAR 235
           L A R
Sbjct: 765 LNAIR 769



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 18/93 (19%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 57   EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEE 116
            E ++++ K +EN  +  E     +   EK   E     T+ REL++    L+ + D    
Sbjct: 1190 ERLRSENKDIENLRREREHLEMEL---EKAEMERSTYVTEVRELKDLLTELQKKLDDSYS 1246

Query: 117  RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEI 149
                  +E+N +K +      +++  +   Q++
Sbjct: 1247 EAVRQNEELNLLKAQLNETLTKLRTEQNERQKV 1279


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 39/203 (19%), Positives = 91/203 (44%), Gaps = 15/203 (7%)

Query: 32  QSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKE-- 89
           +  M++  ++LRE         E  E +Q + +K++  E+ ++E   +    EK LK+  
Sbjct: 440 EEMMQDQEEKLREV---EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496

Query: 90  -LMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQE 148
            + E + K     E+      +  + EE++   E++M E +     +E++++  E  LQE
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556

Query: 149 IWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYS 208
           + + + +   +   +  +  E+G++   TL  I+         Q  ++ QE Q + Q+  
Sbjct: 557 LEERLGKLGQKAELLGGAGRESGSQRLPTLTPIL---------QVELKSQEAQSLQQQQD 607

Query: 209 SRRATPRHIIVRFTKVEMKEKML 231
             R   +  +  + ++   ++ L
Sbjct: 608 HYRGHLQQYVAAYQQLASGKEAL 630



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 49/220 (22%), Positives = 102/220 (46%), Gaps = 21/220 (9%)

Query: 54  ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
           ++RE  + + +K+   EK + E   +I   E+   E+   + K REL E  +    +  +
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEE---EMWRQEEKIRELEEMMQDQEEKLRE 452

Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPE---SDEEN 170
           +EE++   E++M E       +E++I+R E+ +QE  +   R   +L+   E     EE 
Sbjct: 453 VEEKMQEEEEKMQE-------QEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEK 504

Query: 171 GTKLENTL---QDIIQENFPNLARQ-ANIQIQEIQ--RMSQRYSSRRATPRHIIVRFTKV 224
             + E  +   ++ +QE    + RQ   ++ QE++  +  ++   +    + +  R  K+
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL 564

Query: 225 EMKEKML-RAAREKGRVTLKGKPIRLTADLSAETLQARRE 263
             K ++L  A RE G   L      L  +L ++  Q+ ++
Sbjct: 565 GQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 35/185 (18%), Positives = 88/185 (47%), Gaps = 8/185 (4%)

Query: 57  EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEE 116
           E +  + +K++  E+ + E   +I   E+   ++   + K  E  E+ R    +  + EE
Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEE---KMWRQEEKMHEQEEKIREQEDKMWRQEE 353

Query: 117 RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLEN 176
           ++   E+++ E +++   +E++I+  ++ +QE  + + R   ++    E  +E   + E 
Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413

Query: 177 TLQ---DIIQENFPNLARQANIQIQEIQRMSQRYSSR-RATPRHIIVRFTKVEMKEKMLR 232
            ++   + I+E    + RQ   +I+E++ M Q    + R     +     K++ +E+ ++
Sbjct: 414 KMREQDEKIREQEEEMWRQEE-KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472

Query: 233 AAREK 237
              EK
Sbjct: 473 RQEEK 477



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 47/227 (20%), Positives = 94/227 (41%), Gaps = 12/227 (5%)

Query: 20  PPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITR 79
           P  E   +  T++   E + +   +     S  SE++ +++   +K+E  +  L +   +
Sbjct: 202 PSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQ 261

Query: 80  ITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEM-----KQEGKV 134
           +   ++  KEL  +  K +   EE         Q EE++   E+++ E      +QE K+
Sbjct: 262 V-EADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKI 320

Query: 135 REKRIK--RNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQ 192
           RE+  K  R E+ + E  + ++    ++    E   E   K+    + + ++      + 
Sbjct: 321 REQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD 380

Query: 193 ANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGR 239
             IQ QE +   Q    R    +    R  K+  +EK +R   EK R
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEK----RQEKMWRQEKKMREQDEKIR 423



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 40/193 (20%), Positives = 86/193 (44%), Gaps = 21/193 (10%)

Query: 54  ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
           E  E +  + +K+   E+ + E   ++   E+ ++E  E   K RE  E+      +  +
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE---KIREQEEKMWRQEEKIRE 378

Query: 114 LEERVSAMEDEMNEMKQEGKVRE-------------KRIKRNEQSLQEIWDYVKRPNLRL 160
            +E++   E+EM   +QE K+RE             K+++  ++ ++E  + + R   ++
Sbjct: 379 QDEKIQEQEEEM--WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436

Query: 161 IGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVR 220
             + E  ++   KL    + + +E      ++  IQ QE +   Q   + R     ++ +
Sbjct: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR--QEKLLKQ 494

Query: 221 FTKV-EMKEKMLR 232
             K+ E +EKM R
Sbjct: 495 EEKIWEQEEKMWR 507


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 39/203 (19%), Positives = 91/203 (44%), Gaps = 15/203 (7%)

Query: 32  QSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKE-- 89
           +  M++  ++LRE         E  E +Q + +K++  E+ ++E   +    EK LK+  
Sbjct: 440 EEMMQDQEEKLREV---EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEE 496

Query: 90  -LMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQE 148
            + E + K     E+      +  + EE++   E++M E +     +E++++  E  LQE
Sbjct: 497 KIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQE 556

Query: 149 IWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYS 208
           + + + +   +   +  +  E+G++   TL  I+         Q  ++ QE Q + Q+  
Sbjct: 557 LEERLGKLGQKAELLGGAGRESGSQRLPTLTPIL---------QVELKSQEAQSLQQQQD 607

Query: 209 SRRATPRHIIVRFTKVEMKEKML 231
             R   +  +  + ++   ++ L
Sbjct: 608 HYRGHLQQYVAAYQQLASGKEAL 630



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 49/220 (22%), Positives = 102/220 (46%), Gaps = 21/220 (9%)

Query: 54  ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
           ++RE  + + +K+   EK + E   +I   E+   E+   + K REL E  +    +  +
Sbjct: 396 KIREQEEKRQEKMWRQEKKMREQDEKIREQEE---EMWRQEEKIRELEEMMQDQEEKLRE 452

Query: 114 LEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPE---SDEEN 170
           +EE++   E++M E       +E++I+R E+ +QE  +   R   +L+   E     EE 
Sbjct: 453 VEEKMQEEEEKMQE-------QEEKIQRQEEKIQEQEEKTWRQE-KLLKQEEKIWEQEEK 504

Query: 171 GTKLENTL---QDIIQENFPNLARQ-ANIQIQEIQ--RMSQRYSSRRATPRHIIVRFTKV 224
             + E  +   ++ +QE    + RQ   ++ QE++  +  ++   +    + +  R  K+
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKL 564

Query: 225 EMKEKML-RAAREKGRVTLKGKPIRLTADLSAETLQARRE 263
             K ++L  A RE G   L      L  +L ++  Q+ ++
Sbjct: 565 GQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 35/185 (18%), Positives = 88/185 (47%), Gaps = 8/185 (4%)

Query: 57  EDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEE 116
           E +  + +K++  E+ + E   +I   E+   ++   + K  E  E+ R    +  + EE
Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEE---KMWRQEEKMHEQEEKIREQEDKMWRQEE 353

Query: 117 RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLEN 176
           ++   E+++ E +++   +E++I+  ++ +QE  + + R   ++    E  +E   + E 
Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413

Query: 177 TLQ---DIIQENFPNLARQANIQIQEIQRMSQRYSSR-RATPRHIIVRFTKVEMKEKMLR 232
            ++   + I+E    + RQ   +I+E++ M Q    + R     +     K++ +E+ ++
Sbjct: 414 KMREQDEKIREQEEEMWRQEE-KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472

Query: 233 AAREK 237
              EK
Sbjct: 473 RQEEK 477



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 40/193 (20%), Positives = 86/193 (44%), Gaps = 21/193 (10%)

Query: 54  ELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQ 113
           E  E +  + +K+   E+ + E   ++   E+ ++E  E   K RE  E+      +  +
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE---KIREQEEKMWRQEEKIRE 378

Query: 114 LEERVSAMEDEMNEMKQEGKVRE-------------KRIKRNEQSLQEIWDYVKRPNLRL 160
            +E++   E+EM   +QE K+RE             K+++  ++ ++E  + + R   ++
Sbjct: 379 QDEKIQEQEEEM--WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436

Query: 161 IGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVR 220
             + E  ++   KL    + + +E      ++  IQ QE +   Q   + R     ++ +
Sbjct: 437 RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR--QEKLLKQ 494

Query: 221 FTKV-EMKEKMLR 232
             K+ E +EKM R
Sbjct: 495 EEKIWEQEEKMWR 507



 Score = 36.2 bits (82), Expect = 0.043
 Identities = 45/217 (20%), Positives = 91/217 (41%), Gaps = 12/217 (5%)

Query: 30  TEQSWMENDFDELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKE 89
           T++   E + +   +     S  SE++ +++   +K+E  +  L +   ++   ++  KE
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQV-EADRLGKE 270

Query: 90  LMELKTKARELREECRSLRSRCDQLEERVSAMEDEMNEM-----KQEGKVREKRIK--RN 142
           L  +  K +   EE         Q EE++   E+++ E      +QE K+RE+  K  R 
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330

Query: 143 EQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQR 202
           E+ + E  + ++    ++    E   E   K+    + + ++      +   IQ QE + 
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390

Query: 203 MSQRYSSRRATPRHIIVRFTKVEMKEKMLRAAREKGR 239
             Q    R    +    R  K+  +EK +R   EK R
Sbjct: 391 WRQEEKIREQEEK----RQEKMWRQEKKMREQDEKIR 423


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 62/285 (21%), Positives = 119/285 (41%), Gaps = 32/285 (11%)

Query: 53  SELREDIQTKGKKVENFEKNLEECITRITNTEK----CLKELMELKTKARELREECRSLR 108
           S+++ ++++  K+    E    EC  ++  T +    C   + + + K R L E  +S+ 
Sbjct: 592 SKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVE 651

Query: 109 SRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDE 168
            +   LEE   ++ DE+ +++ +  V E  +K  E   Q+  +  K   L++    ES  
Sbjct: 652 LKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQM----ESHR 707

Query: 169 ENGTKLENTLQDIIQENFPNL--ARQANIQIQ-EIQRMSQRYSSRRATPRHIIVRFTKVE 225
           E   +    L+D I E    +   +  N ++Q E++++   Y   ++       + TK++
Sbjct: 708 EAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHE---KSTKLQ 764

Query: 226 MKEKMLRAAREKGRVTLKGKPIRLTADLSAETLQARREWRPIF------NILKEKNFQPR 279
            +   L    E+ +  LKG       +  A  LQ     R +F       + K    +P 
Sbjct: 765 -ELTFLYERHEQSKQDLKG-----LEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPE 818

Query: 280 -----ISYAAKLSFISEG-EIKYFIDKQMLRDFVTTRPALQELLK 318
                 S   K+SF+    E    + KQ++RD    R  L +L K
Sbjct: 819 DSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEK 863



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 13/96 (13%)

Query: 59  IQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERV 118
           I ++ +K+   E NLE+    +T   K      +L     +LR E   L  R     ERV
Sbjct: 823 IHSQKQKISFLENNLEQ----LTKVHK------QLVRDNADLRCELPKLEKRLRATAERV 872

Query: 119 SAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVK 154
            A+E  + E K EG +++KR  R +Q +  I + V+
Sbjct: 873 KALEGALKEAK-EGAMKDKR--RYQQEVDRIKEAVR 905


>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
          Length = 1478

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 40/200 (20%), Positives = 86/200 (43%), Gaps = 12/200 (6%)

Query: 59   IQTKGKKVENFEKNLEECITRITNTEK--CLKELMELKTKARELREECRSLRSRCDQLEE 116
            +Q +  + E   ++L+E   +  NT K     E+M+ +++ +   EEC+SLR + ++   
Sbjct: 978  LQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGR 1037

Query: 117  RVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLEN 176
            ++ A E+ + ++K       +++      L E    + R +     + E  E    +LE 
Sbjct: 1038 QLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKEGAALREDLERTQKELEK 1097

Query: 177  TLQDIIQENFPNLARQANIQIQEIQRMSQRYSSRRATPRHIIVRFTKVEMKEKMLRAARE 236
                 IQE +  L ++   + +  Q+M         T ++         ++E+++   R+
Sbjct: 1098 ATTK-IQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKY---------LEERLIELLRD 1147

Query: 237  KGRVTLKGKPIRLTADLSAE 256
            K  +  K   +     LSAE
Sbjct: 1148 KDALWQKSDALEFQQKLSAE 1167



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 32/177 (18%), Positives = 75/177 (42%), Gaps = 10/177 (5%)

Query: 4   KQSRKTGNSKKQSASPPPKECSSSPATEQSWMENDFDELREAGFRRSNYSELREDIQTKG 63
           +Q   T +  K    P P + +         M+   ++L+     R+   E+      + 
Sbjct: 376 QQKADTASDTKGRQEPIPSDAAQE-------MQELGEKLQALERERTKVEEVNRQ---QS 425

Query: 64  KKVENFEKNLEECITRITNTEKCLKELMELKTKARELREECRSLRSRCDQLEERVSAMED 123
            ++E   K L+       + E+ +KE+  L+ +     +E   L  R  +L    S+ E+
Sbjct: 426 AQLEQLVKELQLKEDARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEE 485

Query: 124 EMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRLIGVPESDEENGTKLENTLQD 180
           E+ E+++E K +++  +  EQ ++ +   ++    +L  V +   +   + +  +QD
Sbjct: 486 ELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQD 542



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 34/173 (19%), Positives = 76/173 (43%), Gaps = 4/173 (2%)

Query: 41  ELREAGFRRSNYSELREDIQTKGKKVENFEKNLEECITRITNTEKCLKELMELKTKAREL 100
           EL  AG +      +   +Q    K E  ++ L+E     T  ++  +E  EL+   REL
Sbjct: 563 ELPVAGEKNEALVPVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQE-EELRQANREL 621

Query: 101 REECRSLRSRCDQLEERVSAMEDEMNEMKQEGKVREKRIKRNEQSLQEIWDYVKRPNLRL 160
            +E +++  R   LE ++ A++ +   ++Q     +  +   E     I     +    L
Sbjct: 622 EKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASL 681

Query: 161 IGVPESDEENGTKLENTLQDIIQENFPNLARQANIQIQEIQRMSQ-RYSSRRA 212
           + V ++ E    K +   ++ I ++     +Q   ++++ Q++++ R+   RA
Sbjct: 682 LAVRKAKE--AMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRA 732


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,420,089
Number of Sequences: 37866
Number of extensions: 549074
Number of successful extensions: 5701
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 257
Number of HSP's successfully gapped in prelim test: 608
Number of HSP's that attempted gapping in prelim test: 3317
Number of HSP's gapped (non-prelim): 2336
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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