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Search of human proteins with 239742343
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239742343 PREDICTED: hypothetical protein XP_002342497 [Homo
sapiens]
(208 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239748415 PREDICTED: hypothetical protein [Homo sapiens] 427 e-120
gi|239742343 PREDICTED: hypothetical protein XP_002342497 [Homo ... 427 e-120
gi|239753856 PREDICTED: hypothetical protein [Homo sapiens] 426 e-120
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 52 3e-07
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 52 3e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni... 52 5e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 51 6e-07
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote... 49 3e-06
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 49 3e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 49 3e-06
gi|239756307 PREDICTED: similar to ubiquitin-associated protein ... 49 4e-06
gi|239750857 PREDICTED: similar to ubiquitin-associated protein ... 49 4e-06
gi|239745220 PREDICTED: hypothetical protein [Homo sapiens] 49 4e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 48 5e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 48 5e-06
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 47 1e-05
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 47 2e-05
gi|40353727 synaptopodin isoform A [Homo sapiens] 46 3e-05
gi|58331144 proline rich region 18 [Homo sapiens] 46 3e-05
gi|117938768 GNAS complex locus alex [Homo sapiens] 45 3e-05
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 45 3e-05
gi|55741677 SET domain containing 1A [Homo sapiens] 45 6e-05
gi|18959210 WIRE protein [Homo sapiens] 45 6e-05
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 45 6e-05
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 44 7e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 7e-05
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 44 7e-05
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 44 7e-05
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 44 7e-05
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 44 1e-04
>gi|239748415 PREDICTED: hypothetical protein [Homo sapiens]
Length = 208
Score = 427 bits (1099), Expect = e-120
Identities = 208/208 (100%), Positives = 208/208 (100%)
Query: 1 MDELEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRL 60
MDELEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRL
Sbjct: 1 MDELEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRL 60
Query: 61 RQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRR 120
RQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRR
Sbjct: 61 RQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRR 120
Query: 121 QLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLL 180
QLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLL
Sbjct: 121 QLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLL 180
Query: 181 LRRPQLPPHSETFLPVLDSGTALTGRPL 208
LRRPQLPPHSETFLPVLDSGTALTGRPL
Sbjct: 181 LRRPQLPPHSETFLPVLDSGTALTGRPL 208
>gi|239742343 PREDICTED: hypothetical protein XP_002342497 [Homo
sapiens]
Length = 208
Score = 427 bits (1099), Expect = e-120
Identities = 208/208 (100%), Positives = 208/208 (100%)
Query: 1 MDELEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRL 60
MDELEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRL
Sbjct: 1 MDELEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRL 60
Query: 61 RQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRR 120
RQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRR
Sbjct: 61 RQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRR 120
Query: 121 QLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLL 180
QLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLL
Sbjct: 121 QLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLL 180
Query: 181 LRRPQLPPHSETFLPVLDSGTALTGRPL 208
LRRPQLPPHSETFLPVLDSGTALTGRPL
Sbjct: 181 LRRPQLPPHSETFLPVLDSGTALTGRPL 208
>gi|239753856 PREDICTED: hypothetical protein [Homo sapiens]
Length = 208
Score = 426 bits (1094), Expect = e-120
Identities = 207/208 (99%), Positives = 207/208 (99%)
Query: 1 MDELEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRL 60
MDELEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRL
Sbjct: 1 MDELEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRL 60
Query: 61 RQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRR 120
RQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRR
Sbjct: 61 RQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRR 120
Query: 121 QLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLL 180
QL KGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLL
Sbjct: 121 QLPKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLL 180
Query: 181 LRRPQLPPHSETFLPVLDSGTALTGRPL 208
LRRPQLPPHSETFLPVLDSGTALTGRPL
Sbjct: 181 LRRPQLPPHSETFLPVLDSGTALTGRPL 208
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 52.4 bits (124), Expect = 3e-07
Identities = 46/126 (36%), Positives = 62/126 (49%), Gaps = 15/126 (11%)
Query: 76 LRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNA-GPRRQLAK---GVPLRPG 131
LR +R+ PPPP PP+ L++ SG + + P P + A GPRR+ G PG
Sbjct: 779 LRARRKGPPPP--PPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPG 836
Query: 132 AEPPAPASD-PDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLR-RPQLPPH 189
PPAPA D E PG +PP +SG+G+P G T+ R +P PP
Sbjct: 837 --PPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEE-----GNLTIKQRPKPAGPPP 889
Query: 190 SETFLP 195
ET +P
Sbjct: 890 RETPVP 895
Score = 33.9 bits (76), Expect = 0.10
Identities = 57/239 (23%), Positives = 77/239 (32%), Gaps = 57/239 (23%)
Query: 1 MDELEAPTATARGTAS---SRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRR 57
+DE P A G S GP P P GP + + + P G
Sbjct: 807 LDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPE------GTPPS 860
Query: 58 RRLRQRDPPADREGEREVLRGQRESPPPPQ---LPPELLTNPSGS-AIQSSPSRFRRVPA 113
R P EG + + + + PPP+ +PP L N + S ++ P R P
Sbjct: 861 RGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPL 920
Query: 114 DNA-----------GPRRQLAKGVPLR-------PGAEP-------------PAPASDPD 142
A GP L P P EP P+PA P
Sbjct: 921 QTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPP 980
Query: 143 LEPTPPGGLKS-----------PPLPCASGQGVP--GTRRRQNKLGVETLLLRRPQLPP 188
+ P P GL+S PP A+ VP GT + + L P+L P
Sbjct: 981 VPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAP 1039
Score = 31.6 bits (70), Expect = 0.50
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 3/82 (3%)
Query: 87 QLPPELLTNPSGSAIQSSPSRFRRVPA-DNAGPRRQLAKGVPLRPGAEPPAPASDPDLEP 145
+L PEL +G + P R P+ ++ G R + + +P +P P E
Sbjct: 589 ELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQER 648
Query: 146 TPPGGLKSPPLPCAS--GQGVP 165
P G + PP C+S GQG P
Sbjct: 649 NLPEGTERPPKLCSSLPGQGPP 670
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 52.4 bits (124), Expect = 3e-07
Identities = 46/126 (36%), Positives = 62/126 (49%), Gaps = 15/126 (11%)
Query: 76 LRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNA-GPRRQLAK---GVPLRPG 131
LR +R+ PPPP PP+ L++ SG + + P P + A GPRR+ G PG
Sbjct: 861 LRARRKGPPPP--PPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPG 918
Query: 132 AEPPAPASD-PDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLR-RPQLPPH 189
PPAPA D E PG +PP +SG+G+P G T+ R +P PP
Sbjct: 919 --PPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEE-----GNLTIKQRPKPAGPPP 971
Query: 190 SETFLP 195
ET +P
Sbjct: 972 RETPVP 977
Score = 33.9 bits (76), Expect = 0.10
Identities = 57/239 (23%), Positives = 77/239 (32%), Gaps = 57/239 (23%)
Query: 1 MDELEAPTATARGTAS---SRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRR 57
+DE P A G S GP P P GP + + + P G
Sbjct: 889 LDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPE------GTPPS 942
Query: 58 RRLRQRDPPADREGEREVLRGQRESPPPPQ---LPPELLTNPSGS-AIQSSPSRFRRVPA 113
R P EG + + + + PPP+ +PP L N + S ++ P R P
Sbjct: 943 RGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPL 1002
Query: 114 DNA-----------GPRRQLAKGVPLR-------PGAEP-------------PAPASDPD 142
A GP L P P EP P+PA P
Sbjct: 1003 QTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPP 1062
Query: 143 LEPTPPGGLKS-----------PPLPCASGQGVP--GTRRRQNKLGVETLLLRRPQLPP 188
+ P P GL+S PP A+ VP GT + + L P+L P
Sbjct: 1063 VPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAP 1121
Score = 31.6 bits (70), Expect = 0.50
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 3/82 (3%)
Query: 87 QLPPELLTNPSGSAIQSSPSRFRRVPA-DNAGPRRQLAKGVPLRPGAEPPAPASDPDLEP 145
+L PEL +G + P R P+ ++ G R + + +P +P P E
Sbjct: 671 ELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQER 730
Query: 146 TPPGGLKSPPLPCAS--GQGVP 165
P G + PP C+S GQG P
Sbjct: 731 NLPEGTERPPKLCSSLPGQGPP 752
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 51.6 bits (122), Expect = 5e-07
Identities = 48/176 (27%), Positives = 65/176 (36%), Gaps = 42/176 (23%)
Query: 6 APTATARGTASSRGCGPGT-----------APPPSCGRGPETPSRSQSPKLRRVAKVAGQ 54
APT A S +G GP T A PPS GP TPS +P V
Sbjct: 962 APTPPAATPPSPKG-GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT----- 1015
Query: 55 LRRRRLRQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAI-QSSPSR-FRRVP 112
PP+ + + S PP PP +P+ + + + +P+ +P
Sbjct: 1016 ----------PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP 1065
Query: 113 ADNAGPRRQLAKGVPLRPGAEPPAPASDP-------------DLEPTPPGGLKSPP 155
+ GP KG P P A PP+P P P+P GGL +PP
Sbjct: 1066 SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121
Score = 47.0 bits (110), Expect = 1e-05
Identities = 48/184 (26%), Positives = 62/184 (33%), Gaps = 24/184 (13%)
Query: 6 APTATARGTASSRGCG--PGTAPPPSC------GRGPETPSRSQSPKLRRVAKVAGQLRR 57
APT +A S +G P P PS GP TP+ Q+P L + + R
Sbjct: 864 APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARA 923
Query: 58 RRLRQRDP--------PADREGEREVLRGQRESPPPPQLP-PELLTNPSGSAIQSSPSR- 107
+ P P +G +P P P P T PS ++PS
Sbjct: 924 TPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK 983
Query: 108 ------FRRVPADNAGPRRQLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASG 161
P+ GP KG P P PP+P P P P G P S
Sbjct: 984 GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043
Query: 162 QGVP 165
+G P
Sbjct: 1044 KGSP 1047
Score = 46.2 bits (108), Expect = 2e-05
Identities = 59/224 (26%), Positives = 81/224 (36%), Gaps = 39/224 (17%)
Query: 6 APTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDP 65
APT A S +G A PS GP TPS + P A + P
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP-----TPPAATPSHKGGPAMTP 1386
Query: 66 PADREGER-EVLRGQRESPP----PPQLPPELLTNPSGSAIQS---------SPSRFRRV 111
P+ + G +G SP P+ P G+A S +P ++
Sbjct: 1387 PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKA 1446
Query: 112 PADNA---GPRRQLAKGVPLRPGAEPPAP-----------ASDPDLEPTPPGGLKSPPLP 157
PA +A GP +KG P P PP+P +S P P P + +P LP
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506
Query: 158 C---ASGQGVPGT--RRRQNKLGVETLLLRR-PQLPPHSETFLP 195
+S + VP T RR TLL ++ P E +P
Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550
Score = 45.1 bits (105), Expect = 4e-05
Identities = 42/152 (27%), Positives = 52/152 (34%), Gaps = 26/152 (17%)
Query: 22 PGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRGQRE 81
P A PPS GP TPS +P PP+ + G +
Sbjct: 942 PPAATPPSPKGGPATPSPKWAPTPPAAT---------------PPSPKGGP--ATPSPKG 984
Query: 82 SPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNA-GPRRQLA-----KGVPLRPGAEPP 135
+P PP P +P G SP PA P+ A KG P A PP
Sbjct: 985 APTPPAATPP---SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041
Query: 136 APASDPDLEPTPPGGLKSPPLPCASGQGVPGT 167
+P P P P G +P S +G P T
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Score = 45.1 bits (105), Expect = 4e-05
Identities = 53/194 (27%), Positives = 66/194 (34%), Gaps = 38/194 (19%)
Query: 6 APTATARGTASSRGCGPGT-----------APPPSCGRGPETPSRSQSPKLRRVAKVAGQ 54
APT A S +G GP T A PPS GP TPS +P + +
Sbjct: 1056 APTTPAATLPSPKG-GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK 1114
Query: 55 LRRRRLRQRDPPADREGEREVLRGQRESPPP---PQLPPELLTNPSGSAIQSSPSRFRRV 111
+ P +G +PPP P P +P G P
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 112 PADNA-GPRRQLA----KGVPLRPGAEPP-------------APASDPDLEPTPPGGLKS 153
PA P+ LA KG P P A PP AP + P+P GGL +
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
Query: 154 PPLPCASGQGVPGT 167
P S +G P T
Sbjct: 1235 P-----SPKGAPTT 1243
Score = 43.9 bits (102), Expect = 1e-04
Identities = 43/170 (25%), Positives = 53/170 (31%), Gaps = 28/170 (16%)
Query: 6 APTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDP 65
APT A S +G GP T PP +G TP + P L+ P
Sbjct: 1240 APTTPAATPPSPKG-GPATPPP----KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 66 PADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKG 125
P+ + G SPP P T PS +P KG
Sbjct: 1295 PSPKGGPAT-------SPPKGAPTPPAATPPSPKGSPGTPP----------------PKG 1331
Query: 126 VPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLG 175
P P PP+P P L T P P P + P +K G
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG 1381
Score = 37.0 bits (84), Expect = 0.012
Identities = 43/188 (22%), Positives = 73/188 (38%), Gaps = 24/188 (12%)
Query: 4 LEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSP-KLRRVAKVAGQLRRRRLRQ 62
+ APT T S P P PS G + P + +P L V K + + + +
Sbjct: 1696 ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDAS 1755
Query: 63 RDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPS-----RFRRVPADNAG 117
P +G + +P ++L P +++ ++PS P
Sbjct: 1756 HSP----KGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLP 1811
Query: 118 PRRQL---AKGVPLRPGAEPPAPASDPDLEPTPP-----GG------LKSPPLPCASGQG 163
P++Q + G+ L ++P APA + +L P P GG L + P P ++G
Sbjct: 1812 PKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP 1871
Query: 164 VPGTRRRQ 171
VP +Q
Sbjct: 1872 VPTPSAKQ 1879
Score = 30.8 bits (68), Expect = 0.85
Identities = 44/168 (26%), Positives = 60/168 (35%), Gaps = 37/168 (22%)
Query: 6 APTATARGTASSRGCGPGTA--PP----PSCGRGPETPSRSQSPKLRRVAKVAGQLRRRR 59
APTAT + P A PP PS + P P+ ++P + +
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS------ 1581
Query: 60 LRQRDPPADREGEREVLRGQRESPPPPQ--LPPELLTNPSGSAIQSSPSRFRRVPADNAG 117
PPA V + P P+ L P +T+PS + P+ P+ G
Sbjct: 1582 -----PPA-------VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAV--TPPSPEKG 1627
Query: 118 PRRQLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVP 165
P KG P P P P+S D PT P + C G VP
Sbjct: 1628 PATPAPKGTPTSP---PVTPSSLKD-SPTSPAS-----VTCKMGATVP 1666
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 51.2 bits (121), Expect = 6e-07
Identities = 39/139 (28%), Positives = 54/139 (38%), Gaps = 12/139 (8%)
Query: 21 GPGTAPPPSCG---RGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLR 77
G PPP G +GP P + Q P + G + R R PP +G
Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQ------GDNKSRS--SRSPPGKPQGPPPQGG 188
Query: 78 GQRESPPPPQLPPELLTNPSGSAIQSSPSRFR-RVPADNAGPRRQLAKGVPLRPGAEPPA 136
Q + PPPP P+ G+ Q P + + P + Q A+ P +P PP
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ 248
Query: 137 PASDPDLEPTPPGGLKSPP 155
+ P P PPG + PP
Sbjct: 249 GGNQPQGPPPPPGKPQGPP 267
Score = 51.2 bits (121), Expect = 6e-07
Identities = 37/139 (26%), Positives = 53/139 (38%), Gaps = 12/139 (8%)
Query: 21 GPGTAPPPSCG---RGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLR 77
G PPP G +GP P + Q P Q + R PP +G
Sbjct: 199 GKPQGPPPQGGNKPQGPPPPGKPQGPP--------PQGDNKSQSARSPPGKPQGPPPQGG 250
Query: 78 GQRESPPPPQLPPELLTNPSGSAIQSSPSRFR-RVPADNAGPRRQLAKGVPLRPGAEPPA 136
Q + PPPP P+ G+ Q P + + P G + + ++ P +P PP
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ 310
Query: 137 PASDPDLEPTPPGGLKSPP 155
+ P P PPG + PP
Sbjct: 311 GGNQPQGPPPPPGKPQGPP 329
Score = 50.1 bits (118), Expect = 1e-06
Identities = 46/172 (26%), Positives = 64/172 (37%), Gaps = 21/172 (12%)
Query: 21 GPGTAPPPSCG---RGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLR 77
G PPP G +GP P + Q P + +K R PP +G
Sbjct: 261 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSS--------RSPPGKPQGPPPQGG 312
Query: 78 GQRESPPPPQLPPELLTNPSGSAIQSSPSRFR-RVPADNAGPRRQLAKGVPLRPGAEPPA 136
Q + PPPP P+ G+ Q P + + P G + + A+ P +P P
Sbjct: 313 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQ 372
Query: 137 PASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLRRPQLPP 188
++P P P GG +P P A G P R + G RP PP
Sbjct: 373 EGNNPQGPPPPAGG--NPQQPQAPPAGQPQGPPRPPQGG-------RPSRPP 415
Score = 47.4 bits (111), Expect = 9e-06
Identities = 37/139 (26%), Positives = 53/139 (38%), Gaps = 13/139 (9%)
Query: 21 GPGTAPPPSCG---RGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLR 77
G PPP G +GP P + Q P + G R R PP +G
Sbjct: 76 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQ------GDKSRS---PRSPPGKPQGPPPQGG 126
Query: 78 GQRESPPPPQLPPELLTNPSGSAIQSSPSRFR-RVPADNAGPRRQLAKGVPLRPGAEPPA 136
Q + PPPP P+ G+ Q P + + P + + ++ P +P PP
Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ 186
Query: 137 PASDPDLEPTPPGGLKSPP 155
+ P P PPG + PP
Sbjct: 187 GGNQPQGPPPPPGKPQGPP 205
Score = 40.8 bits (94), Expect = 8e-04
Identities = 24/91 (26%), Positives = 35/91 (38%)
Query: 65 PPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAK 124
PP +G Q + PPPP P+ G+ Q P + G + + +
Sbjct: 53 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 112
Query: 125 GVPLRPGAEPPAPASDPDLEPTPPGGLKSPP 155
P +P PP + P P PPG + PP
Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 143
Score = 29.6 bits (65), Expect = 1.9
Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 9/82 (10%)
Query: 79 QRESPP-----PPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAE 133
Q ESP P PP+ P G SP + P G + Q P +P
Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPP---SPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 81
Query: 134 PPAPASDPDLEPTPPGGLKSPP 155
PP + P P PPG + PP
Sbjct: 82 PPQGGNKPQ-GPPPPGKPQGPP 102
>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
1 [Homo sapiens]
Length = 828
Score = 48.9 bits (115), Expect = 3e-06
Identities = 46/154 (29%), Positives = 62/154 (40%), Gaps = 13/154 (8%)
Query: 2 DELEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLR 61
+++ +P AT A S GP P P+ GP P R+ L + +V ++ +
Sbjct: 331 EKVVSPPATPDNPADSPAPGPLGPPGPTGPPGPPGPPRNVLSPLN-LEEVQKKVAEQTFI 389
Query: 62 QRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAG---P 118
+ D ++ GQR +PPPP PP T S S P P +G P
Sbjct: 390 KDDYLETISSPKDFGLGQRATPPPPP-PPTYRTVVSSPGPGSGPG-----PGTTSGASSP 443
Query: 119 RRQLAKGVPLR---PGAEPPAPASDPDLEPTPPG 149
R VP R P PP P S P L P PG
Sbjct: 444 ARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPG 477
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 48.9 bits (115), Expect = 3e-06
Identities = 49/185 (26%), Positives = 63/185 (34%), Gaps = 39/185 (21%)
Query: 21 GPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRGQR 80
G G PPP G P P +GQ PP G + Q+
Sbjct: 466 GKGMMPPPPMGMMPPPPPPP-----------SGQ----------PPPPPSGPLPPWQQQQ 504
Query: 81 ESPPPPQLPPELL-------------TNPSGSAIQSSPSRFRRVPADNAGPRRQLAKG-- 125
+ PPPP P + T + + S P ++ A A P +G
Sbjct: 505 QQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNP 564
Query: 126 --VPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLRR 183
VPL PG +PP P P P PP G +P G G P + TL R+
Sbjct: 565 TMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDG-PSHESEDFPRPLVTLPGRQ 623
Query: 184 PQLPP 188
PQ P
Sbjct: 624 PQQRP 628
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 48.9 bits (115), Expect = 3e-06
Identities = 37/138 (26%), Positives = 51/138 (36%), Gaps = 12/138 (8%)
Query: 21 GPGTAPPPSCG---RGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLR 77
G PPP G +GP P + Q P + G R R PP +G
Sbjct: 55 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQ------GDKSRS---PRSPPGKPQGPPPQGG 105
Query: 78 GQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAP 137
Q + PPPP P+ G+ Q P + G + + + P +P PP
Sbjct: 106 NQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165
Query: 138 ASDPDLEPTPPGGLKSPP 155
+ P P PPG + PP
Sbjct: 166 GNQPQGPPPPPGKPQGPP 183
Score = 48.9 bits (115), Expect = 3e-06
Identities = 37/138 (26%), Positives = 51/138 (36%), Gaps = 12/138 (8%)
Query: 21 GPGTAPPPSCG---RGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLR 77
G PPP G +GP P + Q P + G R R PP +G
Sbjct: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQ------GDKSRS---PRSPPGKPQGPPPQGG 166
Query: 78 GQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAP 137
Q + PPPP P+ G Q P + G + + ++ P +P PP
Sbjct: 167 NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG 226
Query: 138 ASDPDLEPTPPGGLKSPP 155
+ P P PPG + PP
Sbjct: 227 GNQPQGPPPPPGKPQGPP 244
Score = 48.9 bits (115), Expect = 3e-06
Identities = 46/172 (26%), Positives = 63/172 (36%), Gaps = 22/172 (12%)
Query: 21 GPGTAPPPSCGR---GPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLR 77
G PPP G+ GP P + Q P + + Q PP +G
Sbjct: 177 GKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQ---------SPPGKPQGPPPQGG 227
Query: 78 GQRESPPPPQLPPELLTNPSGSAIQSSPSRFR-RVPADNAGPRRQLAKGVPLRPGAEPPA 136
Q + PPPP P+ G+ Q P + + P G + Q A+ P +P P
Sbjct: 228 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQ 287
Query: 137 PASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLRRPQLPP 188
++P P P GG +P P A G P R + G RP PP
Sbjct: 288 EGNNPQGPPPPAGG--NPQQPQAPPAGQPQGPPRPPQGG-------RPSRPP 330
Score = 40.8 bits (94), Expect = 8e-04
Identities = 46/188 (24%), Positives = 67/188 (35%), Gaps = 16/188 (8%)
Query: 7 PTATARGTASSRGCGPGTAPPPSCGRGPETPS-RSQSPKLRRVAKVAGQLRRRRLRQRDP 65
P +G G P PPP +GP +S+SP+ + Q P
Sbjct: 114 PPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 173
Query: 66 PADREGEREVLRGQR--ESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLA 123
P + + +G + + PPPP P S SP + P G + Q
Sbjct: 174 PPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP 233
Query: 124 KGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLRR 183
P +P PP + P P PPG + PP QG ++ ++ G +
Sbjct: 234 PPPPGKPQGPPPQGGNKPQ-GPPPPGKPQGPP-----AQGGSKSQSARSPPG-------K 280
Query: 184 PQLPPHSE 191
PQ PP E
Sbjct: 281 PQGPPQQE 288
Score = 37.0 bits (84), Expect = 0.012
Identities = 20/75 (26%), Positives = 30/75 (40%)
Query: 81 ESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPASD 140
+ PPPP P+ G+ Q P + G + + + P +P PP +
Sbjct: 48 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 107
Query: 141 PDLEPTPPGGLKSPP 155
P P PPG + PP
Sbjct: 108 PQGPPPPPGKPQGPP 122
>gi|239756307 PREDICTED: similar to ubiquitin-associated protein 1
(predicted) [Homo sapiens]
Length = 290
Score = 48.5 bits (114), Expect = 4e-06
Identities = 53/191 (27%), Positives = 68/191 (35%), Gaps = 29/191 (15%)
Query: 20 CG-PGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRG 78
CG PGTA P +P +P + + R P + E E E G
Sbjct: 65 CGDPGTASAPPAWLLLVSPEHGLAPAPTTIRDPEAGHQER------PEEEGEDEAEASSG 118
Query: 79 QRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKG------------- 125
E P P L P +P S R V + AG RR+L++G
Sbjct: 119 SEEEPAPSSLQPGSPASPGPGRRLCSLDVLRGVRLELAGARRRLSEGKLVSRPRALLHGL 178
Query: 126 -----VPLRPG-AEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETL 179
+ L P A+ P AS P P P SPP P +G P R +K V
Sbjct: 179 RGHRALSLCPSPAQSPRSASPPGPAPQHPAAPASPPRPSTAGAIPP---LRSHKPTVAVR 235
Query: 180 LLRRPQLPPHS 190
+L P PP S
Sbjct: 236 ILPAPPRPPIS 246
>gi|239750857 PREDICTED: similar to ubiquitin-associated protein 1
(predicted) [Homo sapiens]
Length = 290
Score = 48.5 bits (114), Expect = 4e-06
Identities = 53/191 (27%), Positives = 68/191 (35%), Gaps = 29/191 (15%)
Query: 20 CG-PGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRG 78
CG PGTA P +P +P + + R P + E E E G
Sbjct: 65 CGDPGTASAPPAWLLLVSPEHGLAPAPTTIRDPEAGHQER------PEEEGEDEAEASSG 118
Query: 79 QRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKG------------- 125
E P P L P +P S R V + AG RR+L++G
Sbjct: 119 SEEEPAPSSLQPGSPASPGPGRRLCSLDVLRGVRLELAGARRRLSEGKLVSRPRALLHGL 178
Query: 126 -----VPLRPG-AEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETL 179
+ L P A+ P AS P P P SPP P +G P R +K V
Sbjct: 179 RGHRALSLCPSPAQSPRSASPPGPAPQHPAAPASPPRPSTAGAIPP---LRSHKPTVAVR 235
Query: 180 LLRRPQLPPHS 190
+L P PP S
Sbjct: 236 ILPAPPRPPIS 246
>gi|239745220 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 48.5 bits (114), Expect = 4e-06
Identities = 53/191 (27%), Positives = 68/191 (35%), Gaps = 29/191 (15%)
Query: 20 CG-PGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRG 78
CG PGTA P +P +P + + R P + E E E G
Sbjct: 65 CGDPGTASAPPAWLLLVSPEHGLAPAPTTIRDPEAGHQER------PEEEGEDEAEASSG 118
Query: 79 QRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKG------------- 125
E P P L P +P S R V + AG RR+L++G
Sbjct: 119 SEEEPAPSSLQPGSPASPGPGRRLCSLDVLRGVRLELAGARRRLSEGKLVSRPRALLHGL 178
Query: 126 -----VPLRPG-AEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETL 179
+ L P A+ P AS P P P SPP P +G P R +K V
Sbjct: 179 RGHRALSLCPSPAQSPRSASPPGPAPQHPAAPASPPRPSTAGAIPP---LRSHKPTVAVR 235
Query: 180 LLRRPQLPPHS 190
+L P PP S
Sbjct: 236 ILPAPPRPPIS 246
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 48.1 bits (113), Expect = 5e-06
Identities = 44/164 (26%), Positives = 62/164 (37%), Gaps = 22/164 (13%)
Query: 4 LEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQS-----------PKLRRVAKVA 52
L P A GT PGT PP+ GP P Q+ PK
Sbjct: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 53 GQLRRRRLRQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVP 112
G+ ++ PP + G + L Q P + P P+ + +Q ++P
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP-----GPTKTPVQQPGP--GKIP 450
Query: 113 ADNAGPRRQLAKGV-PLRPGAEPPAPASDPDLEPTPPGGLKSPP 155
A AGP + A+ P +P ++ P PA P P PG K PP
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPP---PQQPGPAKPPP 491
Score = 34.3 bits (77), Expect = 0.077
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 6/77 (7%)
Query: 82 SPPPPQLPPELLTNP---SGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPA 138
+P P P+L T P + + +SSP + P +A P++ L+K + +PP
Sbjct: 651 APVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK---KPPPLV 707
Query: 139 SDPDLEPTPPGGLKSPP 155
P L +P K PP
Sbjct: 708 KQPTLHGSPSAKAKQPP 724
Score = 34.3 bits (77), Expect = 0.077
Identities = 49/195 (25%), Positives = 70/195 (35%), Gaps = 36/195 (18%)
Query: 21 GPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRGQR 80
G T P P G P+ QSPK + Q RR L L
Sbjct: 874 GSPTPPGPRPTAGQTVPTPQQSPKPQE------QSRRFSLN--------------LGSIT 913
Query: 81 ESPPP-PQLPPELLTNPS---GSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPA 136
++P P P E +T G++I S S A GP Q G P++ + PA
Sbjct: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST-AGQPGPHSQSGPGAPMK---QAPA 969
Query: 137 PASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLRRPQLP----PHSET 192
P+ P + P ++PP P S +P ++ E L + Q P +E
Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKS---IP-VKKETKAPAAEKLEPKAEQAPTVKRTETEK 1025
Query: 193 FLPVLDSGTALTGRP 207
P + +LT P
Sbjct: 1026 KPPPIKDSKSLTAEP 1040
Score = 30.4 bits (67), Expect = 1.1
Identities = 26/103 (25%), Positives = 37/103 (35%), Gaps = 9/103 (8%)
Query: 65 PPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAK 124
PPA G + L Q + PP PP P+ + P PA G + ++
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKP------PAQQTGSEKPSSE 384
Query: 125 GVPLRPGAEPPAPASDPDLEP---TPPGGLKSPPLPCASGQGV 164
+ A+PP P +P PP P P A G+
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL 427
Score = 30.0 bits (66), Expect = 1.5
Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 17/77 (22%)
Query: 81 ESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPASD 140
+ P QLP +PS S++ + P F R + L A+PP P
Sbjct: 2369 QEKPASQLPSG---SPSVSSLPAKPRPFFRSSS--------------LDISAQPPPPPPP 2411
Query: 141 PDLEPTPPGGLKSPPLP 157
P P PP PPLP
Sbjct: 2412 PPPPPPPPPPPPPPPLP 2428
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 48.1 bits (113), Expect = 5e-06
Identities = 44/164 (26%), Positives = 62/164 (37%), Gaps = 22/164 (13%)
Query: 4 LEAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQS-----------PKLRRVAKVA 52
L P A GT PGT PP+ GP P Q+ PK
Sbjct: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 53 GQLRRRRLRQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVP 112
G+ ++ PP + G + L Q P + P P+ + +Q ++P
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP-----GPTKTPVQQPGP--GKIP 450
Query: 113 ADNAGPRRQLAKGV-PLRPGAEPPAPASDPDLEPTPPGGLKSPP 155
A AGP + A+ P +P ++ P PA P P PG K PP
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPP---PQQPGPAKPPP 491
Score = 34.3 bits (77), Expect = 0.077
Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 6/77 (7%)
Query: 82 SPPPPQLPPELLTNP---SGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPA 138
+P P P+L T P + + +SSP + P +A P++ L+K + +PP
Sbjct: 651 APVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK---KPPPLV 707
Query: 139 SDPDLEPTPPGGLKSPP 155
P L +P K PP
Sbjct: 708 KQPTLHGSPSAKAKQPP 724
Score = 34.3 bits (77), Expect = 0.077
Identities = 49/195 (25%), Positives = 70/195 (35%), Gaps = 36/195 (18%)
Query: 21 GPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRGQR 80
G T P P G P+ QSPK + Q RR L L
Sbjct: 874 GSPTPPGPRPTAGQTVPTPQQSPKPQE------QSRRFSLN--------------LGSIT 913
Query: 81 ESPPP-PQLPPELLTNPS---GSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPA 136
++P P P E +T G++I S S A GP Q G P++ + PA
Sbjct: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST-AGQPGPHSQSGPGAPMK---QAPA 969
Query: 137 PASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLRRPQLP----PHSET 192
P+ P + P ++PP P S +P ++ E L + Q P +E
Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKS---IP-VKKETKAPAAEKLEPKAEQAPTVKRTETEK 1025
Query: 193 FLPVLDSGTALTGRP 207
P + +LT P
Sbjct: 1026 KPPPIKDSKSLTAEP 1040
Score = 30.4 bits (67), Expect = 1.1
Identities = 26/103 (25%), Positives = 37/103 (35%), Gaps = 9/103 (8%)
Query: 65 PPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAK 124
PPA G + L Q + PP PP P+ + P PA G + ++
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKP------PAQQTGSEKPSSE 384
Query: 125 GVPLRPGAEPPAPASDPDLEP---TPPGGLKSPPLPCASGQGV 164
+ A+PP P +P PP P P A G+
Sbjct: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL 427
Score = 30.0 bits (66), Expect = 1.5
Identities = 23/77 (29%), Positives = 30/77 (38%), Gaps = 17/77 (22%)
Query: 81 ESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPASD 140
+ P QLP +PS S++ + P F R + L A+PP P
Sbjct: 2369 QEKPASQLPSG---SPSVSSLPAKPRPFFRSSS--------------LDISAQPPPPPPP 2411
Query: 141 PDLEPTPPGGLKSPPLP 157
P P PP PPLP
Sbjct: 2412 PPPPPPPPPPPPPPPLP 2428
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 47.0 bits (110), Expect = 1e-05
Identities = 43/155 (27%), Positives = 58/155 (37%), Gaps = 18/155 (11%)
Query: 21 GPGTAPPPSCGRGPETPSRSQSPKLRRV-------AKVAGQLRRRRLRQRDP-PADREG- 71
G T PP P +P ++Q PK RV A V+ L DP P+DR G
Sbjct: 589 GTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGP 648
Query: 72 -------EREVLRGQRESPPPPQLPPEL--LTNPSGSAIQSSPSRFRRVPADNAGPRRQL 122
+R V+ + P P PP NP+ A+ + V +A P+
Sbjct: 649 QILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPP 708
Query: 123 AKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLP 157
L P E P + D P+PP PP P
Sbjct: 709 TPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPP 743
Score = 35.4 bits (80), Expect = 0.035
Identities = 53/219 (24%), Positives = 70/219 (31%), Gaps = 61/219 (27%)
Query: 14 TASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGER 73
T S G G PP P+ S P L G RR PP E
Sbjct: 539 TGGSEGAGAAPCPP--------NPANSWVPGLS-----PGGSRR-------PPRSPERTL 578
Query: 74 EVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRV---------------------- 111
G P LPP+ L P S ++ P + RV
Sbjct: 579 SPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSS 638
Query: 112 ---PADNAGPR--RQLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPC-ASGQGVP 165
P+D +GP+ L + P + PAP S P +P P +P P A+ VP
Sbjct: 639 DPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSP----NPAAPALAAPAVVP 694
Query: 166 GTRRRQNKLGVETLLLRRPQLPPHSETFLPVLDSGTALT 204
G + PQ PP +T L L ++
Sbjct: 695 GPVSTTD---------ASPQSPPTPQTTLTPLQESPVIS 724
Score = 33.5 bits (75), Expect = 0.13
Identities = 38/151 (25%), Positives = 54/151 (35%), Gaps = 23/151 (15%)
Query: 11 ARGTASSRGCGPGTAPPPSCGRGPETPS------RSQSPKLRRVAKVAGQLRRRRLRQRD 64
+ G S PPP G G +PS S + +R +++G+ R +R
Sbjct: 438 SEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRP 497
Query: 65 PPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAK 124
PP R RG P LPP+ P R ++ P P ++
Sbjct: 498 PPPPRRTHSLHQRGLAVPDGPLGLPPK-------------PER-KQQPQLPRPPTTGGSE 543
Query: 125 GVPLRPGAEPPAPASDPDLEPTPPGGLKSPP 155
G P PA + P L PGG + PP
Sbjct: 544 GAGAAPCPPNPANSWVPGLS---PGGSRRPP 571
Score = 28.1 bits (61), Expect = 5.5
Identities = 27/97 (27%), Positives = 38/97 (39%), Gaps = 8/97 (8%)
Query: 64 DPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPA-DNAGPRRQL 122
+ P+ E E L+ PPPP P E + S + F V + + AGP
Sbjct: 752 EAPSASETAEEPLQDPNWPPPPPPAPEE--QDLSMADFPPPEEAFFSVASPEPAGP---- 805
Query: 123 AKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCA 159
G P + + +S L+ PPG PP P A
Sbjct: 806 -SGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPA 841
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 46.6 bits (109), Expect = 2e-05
Identities = 55/203 (27%), Positives = 73/203 (35%), Gaps = 28/203 (13%)
Query: 4 LEAPTATARGTASSRGCGPGTAPPPSCGR---GPETPSRSQSPKLRRVAKVAGQLRRRRL 60
L AP AT S GP + PPP C R P P+ + P R + L
Sbjct: 450 LGAPAATPH---LSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFF 506
Query: 61 RQRDPPAD-------REG-------EREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPS 106
PP REG V +PP P P +N + + SSP+
Sbjct: 507 GTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPA 566
Query: 107 RFRRVPADNAGPRRQLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCAS-GQGVP 165
P P LA+ + P PP+PA +P P P L PP P +S Q
Sbjct: 567 GPVSFP-----PPPYLARSIDPLP--RPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTS 619
Query: 166 GTRRRQNKLGVETLLLRRPQLPP 188
G+ RR + P++ P
Sbjct: 620 GSFRRPESPRPRVSFPKTPEVGP 642
Score = 38.9 bits (89), Expect = 0.003
Identities = 26/76 (34%), Positives = 32/76 (42%), Gaps = 5/76 (6%)
Query: 81 ESPPPPQLPPELLTNPSGS-AIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPAS 139
E P +PP L+ PSG + R R ++ G L G+PL P PP P
Sbjct: 202 EPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTG----LPPGLPLPPPPLPPPPPP 257
Query: 140 DPDLEPTPPGGLKSPP 155
P P PG SPP
Sbjct: 258 PPPPPPPLPGLATSPP 273
Score = 32.0 bits (71), Expect = 0.38
Identities = 53/196 (27%), Positives = 63/196 (32%), Gaps = 29/196 (14%)
Query: 15 ASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPP-------- 66
A S GC P T PP S R SR Q ++ A PP
Sbjct: 344 AESHGCLPATRPPGSDLR----ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTS 399
Query: 67 -ADREGEREVLRGQRESPPPP-----QLPPELLTNPS--GSAIQSSPSRFRRVPADNAGP 118
+ LRG +P P Q P +++ G + SS F PA A P
Sbjct: 400 SSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPA--ATP 457
Query: 119 RRQLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVET 178
L G P + PP P P PP LK P A G + G E
Sbjct: 458 HLSLPPG----PSSPPPPPCPRLLRPPPPPAWLKGPACRAARED---GEILEELFFGTEG 510
Query: 179 LLLRRPQLPPHSETFL 194
P PH E FL
Sbjct: 511 PPRPAPPPLPHREGFL 526
Score = 31.2 bits (69), Expect = 0.65
Identities = 48/188 (25%), Positives = 58/188 (30%), Gaps = 39/188 (20%)
Query: 24 TAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVL-RGQRES 82
T PPP P+RS+S L +++ L R R PAD E G
Sbjct: 896 TQPPPPLSL---PPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERL 952
Query: 83 PPPPQLPPEL--LTNPSGSA------IQSSPSRFRRVPADNAG--PRRQLAKGVPLRP-- 130
PP Q E + SGS Q R RR D+ G PR AK P
Sbjct: 953 LPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKE 1012
Query: 131 -----------------GAEPPAP------ASDPDLEPTPPGGLKSPPLPCASGQGVPGT 167
G E P + P P PP P VPG
Sbjct: 1013 KSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGK 1072
Query: 168 RRRQNKLG 175
+ R+ G
Sbjct: 1073 KAREEAPG 1080
Score = 29.6 bits (65), Expect = 1.9
Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 20/109 (18%)
Query: 83 PPPPQLP------PELLTNPS-GSAIQSS---PSRFRRVPADNAGPRRQLAKGVPLRPGA 132
PPPP LP P LT P S + P R P + R L P A
Sbjct: 260 PPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPA 319
Query: 133 ---EPPA----PASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKL 174
PP PA+ P P PPG LP PG+ R++++
Sbjct: 320 YTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATR---PPGSDLRESRV 365
Score = 28.9 bits (63), Expect = 3.2
Identities = 48/199 (24%), Positives = 72/199 (36%), Gaps = 27/199 (13%)
Query: 4 LEAPTATARGTASSRGCGPGTAPPPSCGRGPET-----PSRSQSPKLRRVAKVAGQLRRR 58
LE RGT ++ PG P GP + P S +P + + + +
Sbjct: 811 LEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQ 870
Query: 59 RLRQRDPPA-DREGEREVLRG---QRESPPPPQLPP-----ELLTNPSGSAIQSSPSRFR 109
P A +R E + G + PPP LPP E+L S A ++ R
Sbjct: 871 FSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEIS-RACETLVERVG 929
Query: 110 RVPADNAGPRRQLAKGVPLRPGAE---PPAPASDPDLEPTPPGGLKSPPLPCASGQGVPG 166
R D A P + P G E PPA A + GG+ + C Q
Sbjct: 930 RSATDPADP---VDTAEPADSGTERLLPPAQAKE------EAGGVAAVSGSCKRRQKEHQ 980
Query: 167 TRRRQNKLGVETLLLRRPQ 185
R+++ + + RRP+
Sbjct: 981 KEHRRHRRACKDSVGRRPR 999
Score = 27.3 bits (59), Expect = 9.4
Identities = 32/101 (31%), Positives = 38/101 (37%), Gaps = 19/101 (18%)
Query: 79 QRESPPPPQL--PPELLTNPSGSAIQSSP-------SRFRRVPADNAGPR---RQLAKGV 126
+ E PPP L PP L P S Q P S + + + G + R V
Sbjct: 766 EEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAV 825
Query: 127 PLRPGAEPPAPASDPDLEPTPPGGLKS-PPLPCA-SGQGVP 165
RPG P S P PP G + PP A S QG P
Sbjct: 826 STRPGPLPTTQYS-----PGPPSGATALPPTSAAPSAQGSP 861
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 45.8 bits (107), Expect = 3e-05
Identities = 56/205 (27%), Positives = 77/205 (37%), Gaps = 46/205 (22%)
Query: 4 LEAPTATARGTASSRG---CGPGTAPPPSCGR-GPETPSRSQSPKLRRVAKVAGQLRRRR 59
L P+ ++ G +S G P PP G P +PSR+ SP+ ++ + + R
Sbjct: 613 LPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAG 672
Query: 60 LRQRD-----------------PPADREG-----EREVLRGQRESPPPPQLPPELLTNPS 97
+ +D PP+ +G E RG S PPP LPP +PS
Sbjct: 673 IEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPP-LPPPPPMSPS 731
Query: 98 GSAIQSSPSRFRRVPADNAGPRRQ-----LAKGV----------PLRPGAEPPAPASDPD 142
S SP R P A P + LA+ + P GAE P P S P
Sbjct: 732 WSERSVSPLR----PETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPR 787
Query: 143 LEPTPPGGLKSPPLPCASGQGVPGT 167
P PP PP + PG+
Sbjct: 788 APPPPPPPPPPPPRMRSPQPARPGS 812
>gi|58331144 proline rich region 18 [Homo sapiens]
Length = 295
Score = 45.8 bits (107), Expect = 3e-05
Identities = 57/205 (27%), Positives = 75/205 (36%), Gaps = 32/205 (15%)
Query: 7 PTATARGTASSRGCG-PGTAPPPSCGRGPET-PSRSQSPKLRRVAKVAGQLRRRRLRQRD 64
P+AT + + RG G T PP G P+ PSR+++P + AG +
Sbjct: 49 PSATLKRPPARRGPGLDRTQPPAPPGVSPQALPSRARAPATCAPPRPAGS--GHSPARTT 106
Query: 65 PPADREGEREVLRGQRESPPP-PQLPPELLTNPSGSAIQSSPSRF----------RRVPA 113
A G G P P N + A+ R R P+
Sbjct: 107 YAATSAGTGTTAAGTSSGAGPCPDSAARFCLNLTPEAVLVIQKRHLEKQLLARPRRPFPS 166
Query: 114 DNAGPRRQLAKGVPLRP-GAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQN 172
+A PRR LA +P R G PASDPD PT G ++PP PG +
Sbjct: 167 PSAEPRRLLAPCLPARAAGPRRGGPASDPDAPPTAGQGRRAPP---------PGAQLLHG 217
Query: 173 KLGVETLLLRRPQLPPHSETFLPVL 197
L V PQL P P+L
Sbjct: 218 GLQV-------PQLSPRPGALRPML 235
>gi|117938768 GNAS complex locus alex [Homo sapiens]
Length = 626
Score = 45.4 bits (106), Expect = 3e-05
Identities = 43/146 (29%), Positives = 65/146 (44%), Gaps = 20/146 (13%)
Query: 23 GTAPPPSCGRGPET-----PSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLR 77
G+ PS P++ PSRS P++R + QLRR++ R ++P R E+ LR
Sbjct: 255 GSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEPLMPRREEKYPLR 314
Query: 78 GQRESPP--PPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPP 135
G PP P ++P L P +P + +++P G + + L PG P
Sbjct: 315 GTDPLPPGQPQRIP--LPGQPLQPQPILTPGQPQKIP--TPGQHQPI-----LTPGHSQP 365
Query: 136 APASDPDLEPTP---PGGLKSP-PLP 157
P L P P PG +P P+P
Sbjct: 366 IPTPGQPLPPQPIPTPGRPLTPQPIP 391
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 45.4 bits (106), Expect = 3e-05
Identities = 45/147 (30%), Positives = 54/147 (36%), Gaps = 14/147 (9%)
Query: 32 RGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRGQRESPPPPQ---- 87
R +PSRS SP R+ K RRR PP R R +PPP +
Sbjct: 520 RRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRR------RSPSPAPPPRRRRTP 573
Query: 88 LPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPASDPDLEPTP 147
PP PS + SPS R P RR P R A PP P P+P
Sbjct: 574 TPPPRRRTPSPPPRRRSPSPRRYSPPIQ---RRYSPSPPPKRRTASPPPPPK-RRASPSP 629
Query: 148 PGGLKSPPLPCASGQGVPGTRRRQNKL 174
P + P + P T+RR L
Sbjct: 630 PPKRRVSHSPPPKQRSSPVTKRRSPSL 656
Score = 42.0 bits (97), Expect = 4e-04
Identities = 42/155 (27%), Positives = 57/155 (36%), Gaps = 9/155 (5%)
Query: 22 PGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLR-----RRRLRQRDPPADREGEREVL 76
P APPP R P P R ++P + R +RR PP R
Sbjct: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP 620
Query: 77 RGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEP-P 135
+R SP PP P +++ +SSP RR P+ ++ R+ + R P P
Sbjct: 621 PKRRASPSPP--PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQP 678
Query: 136 APASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRR 170
P P P SPP P G RR+
Sbjct: 679 NKRHSPSPRPRAPQTSSSPP-PVRRGASSSPQRRQ 712
Score = 41.2 bits (95), Expect = 6e-04
Identities = 39/129 (30%), Positives = 51/129 (39%), Gaps = 16/129 (12%)
Query: 38 SRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPS 97
SRS SP+ R + RRR +R PP R R S P + + S
Sbjct: 306 SRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRH---------RRSRSPVRRRRRSSASLS 356
Query: 98 GSAIQSSPSRFR----RVPADNAGPRRQLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKS 153
GS+ SS SR R + P + P R+ + L P A PP P TPP +
Sbjct: 357 GSSSSSSSSRSRSPPKKPPKRTSSPPRKTRR---LSPSASPPRRRHRPSPPATPPPKTRH 413
Query: 154 PPLPCASGQ 162
P P S +
Sbjct: 414 SPTPQQSNR 422
Score = 32.7 bits (73), Expect = 0.22
Identities = 34/125 (27%), Positives = 44/125 (35%), Gaps = 8/125 (6%)
Query: 34 PETPSRSQSPKLRRVAKVAGQLRRRRLRQRD---PPADREGEREVLRGQRESPPPPQLPP 90
P + SRS+S R + RRR R R P R R +R +PP PP
Sbjct: 276 PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPP 335
Query: 91 ELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPASDPDLEPTPPGG 150
P +S R RR A +G + P +PP S P +
Sbjct: 336 -----PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSP 390
Query: 151 LKSPP 155
SPP
Sbjct: 391 SASPP 395
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 44.7 bits (104), Expect = 6e-05
Identities = 34/98 (34%), Positives = 40/98 (40%), Gaps = 10/98 (10%)
Query: 68 DREGEREVLRGQRESPPPPQLP---PELLTNPSGSAIQSSP----SRFRRVPADNAGPRR 120
D E E SPPP ++P P + P + SP PA AGP
Sbjct: 1064 DEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTE 1123
Query: 121 QLAKGVPLRPG---AEPPAPASDPDLEPTPPGGLKSPP 155
+ PLRP A PPAPA PD P+ P L PP
Sbjct: 1124 ESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPP 1161
Score = 35.4 bits (80), Expect = 0.035
Identities = 40/144 (27%), Positives = 48/144 (33%), Gaps = 23/144 (15%)
Query: 10 TARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVA-KVAGQLRRRRLRQRDPPA- 67
T S G GP T PP P+ S P R + K GQ + D
Sbjct: 526 TGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEI 585
Query: 68 ---DREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAK 124
DR G + PPPP PP P + S P + P Q A
Sbjct: 586 SDDDRGGSPPPAPTPPQQPPPPPPPPP----PPPPYLASLPLGY---------PPHQPAY 632
Query: 125 GVPLRPGAEPPAPASDPDLEPTPP 148
+P RP PP P+ P PP
Sbjct: 633 LLPPRPDGPPP-----PEYPPPPP 651
Score = 28.5 bits (62), Expect = 4.2
Identities = 35/132 (26%), Positives = 45/132 (34%), Gaps = 31/132 (23%)
Query: 93 LTNPSGSAIQSSPSRFRRVPADNAG---------------PRRQLAKGVPLRPGAE---- 133
L++ S S+ SS S+FR A+ PRR + P P AE
Sbjct: 344 LSSSSSSSSSSSSSQFRSSDANYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAE 403
Query: 134 ----------PPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLRR 183
PP P+ D + PP PP P G G G + V T R
Sbjct: 404 RFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRT--SPR 461
Query: 184 PQLPPHSETFLP 195
P P S + P
Sbjct: 462 PASPARSGSPAP 473
Score = 27.7 bits (60), Expect = 7.2
Identities = 35/129 (27%), Positives = 43/129 (33%), Gaps = 13/129 (10%)
Query: 69 REGEREVLRGQRESP--PPPQLPPELLTNPSGS----AIQSSPSRFRRVPADNAGPRRQL 122
R+ EV G P PPP P+GS A + SP + A +
Sbjct: 524 RDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDM 583
Query: 123 AKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLR 182
R G+ PPAP P PP PP + G P + LL
Sbjct: 584 EISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAY-------LLPP 636
Query: 183 RPQLPPHSE 191
RP PP E
Sbjct: 637 RPDGPPPPE 645
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 44.7 bits (104), Expect = 6e-05
Identities = 50/180 (27%), Positives = 64/180 (35%), Gaps = 36/180 (20%)
Query: 1 MDELEAPTATARGTASSRGCGPGTA--PPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRR 58
M P + T SS G ++ PPP GR P +P +K R +
Sbjct: 151 MQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPP---TPLPMHSSKAPAYNREK 207
Query: 59 RLRQRDPPADREGEREVLRGQRESPP------PPQLPPELLTNPSGSAIQSSPSRFRRVP 112
L PP G+R L RE PP PP P + T PSG ++ P +R+ P
Sbjct: 208 PL----PPTP--GQR--LHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPP 259
Query: 113 ADNAGPRRQLAKGVPLRP---------------GAEPPAP--ASDPDLEPTPPGGLKSPP 155
GP + P P G PP P AS L PP + PP
Sbjct: 260 GVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPP 319
Score = 41.2 bits (95), Expect = 6e-04
Identities = 37/141 (26%), Positives = 49/141 (34%), Gaps = 22/141 (15%)
Query: 22 PGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRGQRE 81
P PP GP +P+ +P+L + R L ++ P +RG
Sbjct: 253 PPYRQPPGVPNGPSSPTNESAPELPQ--------RHNSLHRKTPGP--------VRGLAP 296
Query: 82 SPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRP-----GAEPPA 136
PPP P LL+N + PSR P R P P G+EPP+
Sbjct: 297 -PPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPS 355
Query: 137 PASDPDLEPTPPGGLKSPPLP 157
P P G PP P
Sbjct: 356 RGKPPPPPSRTPAGPPPPPPP 376
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 44.7 bits (104), Expect = 6e-05
Identities = 54/195 (27%), Positives = 67/195 (34%), Gaps = 46/195 (23%)
Query: 2 DELEAPTATARGTASSRGCGPGTAPPPSCGRGP-------ETPSRSQSPKLRR-----VA 49
+EL + T + P AP P+ E P R SPK+ R A
Sbjct: 497 EELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAA 556
Query: 50 KVAGQLRRRRLRQRDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFR 109
V RR + R PA + G R SPP P LPP GS +P
Sbjct: 557 PVEDMARRTK---RPAPARPTMPPPQVSGSRSSPPAPPLPP-------GSGSPGTP---- 602
Query: 110 RVPADNAGPRRQLAKGVPLRPGAEPPAPASDPDLEPTPP-----GGLKSP--PLPCASGQ 162
A PRR + G+ AP P L PTPP +SP P P + G
Sbjct: 603 -----QALPRRLV--------GSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGP 649
Query: 163 GVPGTRRRQNKLGVE 177
P N V+
Sbjct: 650 ASPSPVSLSNPAQVD 664
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 44.3 bits (103), Expect = 7e-05
Identities = 57/214 (26%), Positives = 83/214 (38%), Gaps = 31/214 (14%)
Query: 21 GPGTAPPPSC----GRG-PETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREV 75
GP +AP PS GRG P +P R Q L A + R R ++ D+E
Sbjct: 978 GPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDAC 1037
Query: 76 LRGQ-RESPPPPQLP----------PELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAK 124
L E+P PPQ P P L +P +I+ + + R+ + A ++
Sbjct: 1038 LPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSE 1097
Query: 125 GVPLRPGAE---------PPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLG 175
P P + P PA+ EP P P P + Q TR R N+
Sbjct: 1098 LEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQ---ATRSRTNRSS 1154
Query: 176 VET---LLLRRPQLPPHSETFLPVLDSGTALTGR 206
V+T ++ P+L P + T PV T+ R
Sbjct: 1155 VKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTR 1188
Score = 30.0 bits (66), Expect = 1.5
Identities = 52/227 (22%), Positives = 80/227 (35%), Gaps = 30/227 (13%)
Query: 2 DELEAPTATARGTASSRGCGPGTAPPPSCGRGPETP--SRSQSPKLRRVAKVAGQLRRRR 59
D+ P T+R T S P + PE P + ++ P A + R+ R
Sbjct: 1339 DQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNR 1398
Query: 60 LRQRDP----PADREGEREVLRGQRESPPPPQLPPELLTN-----------PSGSAIQSS 104
+ P P + E Q +P P TN P+ +Q S
Sbjct: 1399 SSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPS 1458
Query: 105 PSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPA--SDPDLEPTPPGGLKSPPLPCASGQ 162
S + V + P Q +G R + P + P+L+ + S P S
Sbjct: 1459 TSTDQPVTPE---PTSQATRGRTDRSSVKTPETVVPTAPELQASA-----STDQPVTSEP 1510
Query: 163 GVPGTRRRQNKLGV---ETLLLRRPQLPPHSETFLPVLDSGTALTGR 206
TR R+N+ V ET++ P+L P + T PV T+ R
Sbjct: 1511 TSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATR 1557
Score = 27.7 bits (60), Expect = 7.2
Identities = 41/205 (20%), Positives = 71/205 (34%), Gaps = 20/205 (9%)
Query: 7 PTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRD-- 64
PTA ++S + P RG + S ++P+ V A +LR R
Sbjct: 1245 PTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPE--PVVPTAPELRPSTSTDRPVT 1302
Query: 65 -PPADREGEREVLRGQRESPPP--PQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQ 121
P R ++P P P ++ + + P+ N +
Sbjct: 1303 PKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKN 1362
Query: 122 LAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLL 181
VP+ P PP+ +++ + P P + + G + R + ETL+
Sbjct: 1363 PESTVPIAPEL-PPSTSTEQPVTPEP------------TSRATRGRKNRSSGKTPETLVP 1409
Query: 182 RRPQLPPHSETFLPVLDSGTALTGR 206
P+L P + T PV T+ R
Sbjct: 1410 TAPKLEPSTSTDQPVTPEPTSQATR 1434
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 44.3 bits (103), Expect = 7e-05
Identities = 50/204 (24%), Positives = 75/204 (36%), Gaps = 28/204 (13%)
Query: 7 PTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQL----RRRRLRQ 62
PT R + SS T P P+ R P Q P R ++ A L R +
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 260
Query: 63 RDPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQL 122
P A + +G + PP PP P+ + SSP P+ +A + Q
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP---LATPSPSAALQSQA 317
Query: 123 AKGVPLRPGAE-------------PPAPASDPDLE--PTPPGGLKSPPLPCASGQGVPGT 167
+P P + PP+P++ P L+ P+PP +PP + G P
Sbjct: 318 PPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA---TPPSQATTSLGSPTL 374
Query: 168 RRRQNKL---GVETLLLRRPQLPP 188
+ + L + L PQ PP
Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPP 398
Score = 37.4 bits (85), Expect = 0.009
Identities = 36/110 (32%), Positives = 45/110 (40%), Gaps = 6/110 (5%)
Query: 82 SPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPASDP 141
+PP P PP L T PS A S + + + PL P A PP P + P
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQAT-TSLGSPTLQATHSFLPSPPLSPLATPP-PQAPP 398
Query: 142 DLEPTPPGGLKSPPLPCASGQGVP-GTRRRQNKLGVETLLLRRPQLPPHS 190
L P L++PP P AS P T Q + LL+ P PP S
Sbjct: 399 ALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 445
Score = 35.0 bits (79), Expect = 0.045
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 23/126 (18%)
Query: 84 PPPQLPPELLTNPSGSAIQSSPSRF-RRVPADNAG--PRRQLAKGVPLRPGA-------E 133
PPPQ PP L T P A+ S P+ F + P + P LA P P
Sbjct: 515 PPPQAPPALATPPL-QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 573
Query: 134 PPAPASDPDLE-------PTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLRRPQL 186
PP+P + P L+ P P + P L A G P R + L P L
Sbjct: 574 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS-----PSSTLSGPDL 628
Query: 187 PPHSET 192
HS +
Sbjct: 629 AGHSSS 634
Score = 30.8 bits (68), Expect = 0.85
Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 8/84 (9%)
Query: 84 PPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPASDPDL 143
PPPQ PP L P +Q + + PA P + L PG P +P++ +
Sbjct: 497 PPPQAPPPLAAPP----LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 552
Query: 144 EP--TPPGGLKSPPLPCASGQGVP 165
P TPP ++PP+ A VP
Sbjct: 553 SPLATPPP--QAPPVLAAPLLQVP 574
Score = 30.4 bits (67), Expect = 1.1
Identities = 33/125 (26%), Positives = 43/125 (34%), Gaps = 19/125 (15%)
Query: 82 SPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEP------- 134
SPPP + P+ + S + + P A P Q+ P P P
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500
Query: 135 -PAPASDPDLE-----PTPPGGLKSPPL-----PCASGQGVPGTRRRQNKLGVETLLLRR 183
P P + P L+ P P L +PPL P AS G L + L
Sbjct: 501 APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG-QAPFSPSASLPMSPLATPP 559
Query: 184 PQLPP 188
PQ PP
Sbjct: 560 PQAPP 564
Score = 29.6 bits (65), Expect = 1.9
Identities = 40/148 (27%), Positives = 53/148 (35%), Gaps = 19/148 (12%)
Query: 5 EAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRD 64
+A A T ++R G T PP G P +P RV AG + R+
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPP----GSPRPPPPVTPAALRVLGAAGAVGRK------ 56
Query: 65 PPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAK 124
P A+R G G + P P P+ SA SS + R PA G R AK
Sbjct: 57 PLAERAG------GIGGATIPESAPR---AGPTRSAGTSSRNPASRPPASGRGERAPPAK 107
Query: 125 GVPLRPGAEPPAPASDPDLEPTPPGGLK 152
P + P + P GL+
Sbjct: 108 NTSPGPVSSPGRASGTTRPGPLGQKGLR 135
Score = 28.5 bits (62), Expect = 4.2
Identities = 45/182 (24%), Positives = 60/182 (32%), Gaps = 39/182 (21%)
Query: 1 MDELEAPTATARGTA-----SSRGCGPGTAPPPSCG---RGP---ETPSRSQSPKLRRVA 49
+ L +P A+ G A +S P PPP P PS SP L+
Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP- 586
Query: 50 KVAGQLRRRRLRQRDPPADREGEREVLRGQRESPPPP-QLPPELLTNPS----GSAIQSS 104
RR P G R L PPPP + P L+ P S+ S+
Sbjct: 587 --------RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 638
Query: 105 PSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGV 164
P R ++GP G +P D +L P P P + +G
Sbjct: 639 PEELRGY---DSGPE-----------GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 684
Query: 165 PG 166
PG
Sbjct: 685 PG 686
Score = 27.7 bits (60), Expect = 7.2
Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 17/89 (19%)
Query: 84 PPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGV-----PLRPGAEPP--- 135
PPPQ P L P A S P+ P P+ A V P P PP
Sbjct: 392 PPPQAP-PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
Query: 136 --APASDPDLEP--TPPG----GLKSPPL 156
+P + P + P TPP L +PPL
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPL 479
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 44.3 bits (103), Expect = 7e-05
Identities = 57/185 (30%), Positives = 69/185 (37%), Gaps = 31/185 (16%)
Query: 22 PGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADRE-------GERE 74
PG P GP S SQ P+L + + R PP DR+ GE
Sbjct: 420 PGPPEFPQHTPGPVPNSFSQPPRLPL---------QDQWRAPPPPQDRDPFFLGVSGEPR 470
Query: 75 V---LRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRV-PADN-AGPRRQLAKGVPLR 129
L ++ SPPPP PP LL N S SP F + PA N G + + P+R
Sbjct: 471 FPSHLFLEQRSPPPPPPPPTLL-NSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVR 529
Query: 130 PGAEPPAPA-----SDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKLGVETLLLRRP 184
P +PP P S P T P P GQ T + N G L P
Sbjct: 530 PALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGP----LHPP 585
Query: 185 QLPPH 189
PPH
Sbjct: 586 LPPPH 590
Score = 27.7 bits (60), Expect = 7.2
Identities = 38/174 (21%), Positives = 65/174 (37%), Gaps = 22/174 (12%)
Query: 25 APPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRGQRESPP 84
+PP G + K++ + VA + P D E L+ + +
Sbjct: 741 SPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQK-- 798
Query: 85 PPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAKGVPLRPGAEPPAPASDPDLE 144
+L E+L Q + +R + + A ++QL PPA + L
Sbjct: 799 --RLREEILKQKELRRQQQAGARKKELLERLAQQQQQLY-------APPPPAEQEEQALS 849
Query: 145 PTPPGGLKSPPLPCASGQGVPGTRRRQ---NKLGVETLLLRRPQLPPHSETFLP 195
P+P G +P LP PG + RQ N+L V+ + + P + F+P
Sbjct: 850 PSPTNG--NPLLP------FPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVP 895
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 44.3 bits (103), Expect = 7e-05
Identities = 42/158 (26%), Positives = 55/158 (34%), Gaps = 42/158 (26%)
Query: 21 GPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVLRGQR 80
G G PPP G P P +GQ PP G + Q+
Sbjct: 466 GKGMMPPPPMGMMPPPPPPP-----------SGQ----------PPPPPSGPLPPWQQQQ 504
Query: 81 ESPPPPQLPPELL-------------TNPSGSAIQSSPSRFRRVPADNAGPRRQLAKG-- 125
+ PPPP P + T + + S P ++ A A P +G
Sbjct: 505 QQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNP 564
Query: 126 --VPLRPGAEPPAPASDPDLEPTPPGG----LKSPPLP 157
VPL PG +PP P P P PP G + +PP P
Sbjct: 565 TMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPP 602
Score = 27.7 bits (60), Expect = 7.2
Identities = 42/188 (22%), Positives = 58/188 (30%), Gaps = 45/188 (23%)
Query: 5 EAPTATARGTASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRD 64
EAP + G+ S GP T P S R P P+ + P + + R
Sbjct: 322 EAPVPASVGSTS----GPATTPLASAPR-PAAPANNPPPP-----SLMSTTQSRPPWMNS 371
Query: 65 PPADREGEREVLRGQRESPP--PPQLP---PELLTNPSGSAIQSSPSRFRRVPADNAGPR 119
P++ + G P P P P L G +Q +P+ P
Sbjct: 372 GPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPN--------GPPPP 423
Query: 120 RQLAKGVPLRPGAEPPAPASDPDLE----------------------PTPPGGLKSPPLP 157
P+ G PP P ++ P PP G+ PP P
Sbjct: 424 WMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPP 483
Query: 158 CASGQGVP 165
SGQ P
Sbjct: 484 PPSGQPPP 491
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 44.3 bits (103), Expect = 7e-05
Identities = 52/184 (28%), Positives = 62/184 (33%), Gaps = 32/184 (17%)
Query: 2 DELEAPTATARGTASSRGCGP---GTAPPPSCGRGPETPSRSQSPKLRRVAKVAGQLRRR 58
+E E ++ +SS G GP G P P C R L R VAG
Sbjct: 670 EEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSR----EGACSCLPLERGDAVAGWGGHP 725
Query: 59 RLRQRDPPADREGEREVLRGQRESP--PPPQLPPELLTNPSGSAIQSSPSRFRRVPADNA 116
L PP D R + P PP PPE L G+A P R
Sbjct: 726 ALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGR--------- 776
Query: 117 GPRRQLAKGVPLRPGAEPPAPAS--DPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKL 174
G P P PP P + DP P PP + SP SG PG + +
Sbjct: 777 --------GPPPAPPPPPPPPRAPADPAASPDPPSAVASP----GSGLSSPGPKPGDSGY 824
Query: 175 GVET 178
ET
Sbjct: 825 ETET 828
Score = 30.0 bits (66), Expect = 1.5
Identities = 43/172 (25%), Positives = 61/172 (35%), Gaps = 28/172 (16%)
Query: 23 GTAPPPSCGRGPETPSRSQSPKLRRVAKVAG---QLRRRRLRQRDPPADREGEREVLRGQ 79
GT P + R PET ++P R+ +G + P + + + +
Sbjct: 1111 GTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNT 1170
Query: 80 RESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPA---DNAGPRRQLAKGVPLRPGAEPPA 136
R PPPP LPP P ++ +P R R A + P + L +PP
Sbjct: 1171 RPQPPPPPLPPPPEAQP--RRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPK 1228
Query: 137 P-ASDPD-----LEPTPPGG-------------LKSPPLPCASGQGVPGTRR 169
P P+ L+ PP G L PPL G PG RR
Sbjct: 1229 PERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPG-PGPRR 1279
Score = 28.9 bits (63), Expect = 3.2
Identities = 33/106 (31%), Positives = 40/106 (37%), Gaps = 28/106 (26%)
Query: 77 RGQRESPPPPQLPPELLTNPSGS----AIQSSPSRFRRVPADNAG--------------- 117
RG +PPPP PP +P+ S + +SP P G
Sbjct: 776 RGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGA 835
Query: 118 -PRRQLAK--GVPLRPGA--EPP---APASDPDLEPTPPGGLKSPP 155
P A+ GVP RP A EPP AP PD P P G + P
Sbjct: 836 FPGGGAAEEEGVP-RPRAPPEPPDPGAPRPPPDPGPLPLPGPREKP 880
Score = 28.9 bits (63), Expect = 3.2
Identities = 13/32 (40%), Positives = 15/32 (46%), Gaps = 4/32 (12%)
Query: 134 PPAPASDPDLEPTPPGGLKSPPLPCASGQGVP 165
PP +DP P PP +PP P G G P
Sbjct: 1405 PPEGDTDPSTPPAPP----TPPHPATPGDGFP 1432
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 43.9 bits (102), Expect = 1e-04
Identities = 60/214 (28%), Positives = 78/214 (36%), Gaps = 49/214 (22%)
Query: 15 ASSRGCGPGTAPPPSCGRGPETPSRSQSPKLRRVAK---------VAGQLRR-----RRL 60
A G P T P + GP S + +PK K V+ + R RR
Sbjct: 487 AGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
Query: 61 RQRDPPADREGE-REVLRGQ-RESPPPPQLPPELLTNPSGSAIQSSP----SRFRRVPAD 114
DPP + E VLR SPP PQ P + + P S+P + R + +
Sbjct: 547 MDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILRE 606
Query: 115 NAGPRRQLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKL 174
L + +P PP PA P P+P PP P S +
Sbjct: 607 PTFRWTSLTRELP------PPPPAPPPPPAPSP------PPAPATSSR------------ 642
Query: 175 GVETLLLRRPQLPPHSETFLPVLDSGTALTGRPL 208
LLLR PQ P SE L + +S LT PL
Sbjct: 643 --RPLLLRAPQFTP-SEAHLKIYES--VLTPPPL 671
Score = 33.9 bits (76), Expect = 0.10
Identities = 32/102 (31%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 64 DPPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFR--RVPADNAGPRRQ 121
DPP D + ++ G E P Q L SGSA +P F R+ N P R+
Sbjct: 1819 DPPLDTD---VLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRR 1875
Query: 122 LAKGVPLRPGAEPPAPAS---------DPDLEPTPPGGLKSP 154
GV P P +P+S DPD P PP + P
Sbjct: 1876 PLGGVSFGPLPSPGSPSSLTHHIPTVGDPDF-PAPPRRSRRP 1916
Score = 32.0 bits (71), Expect = 0.38
Identities = 28/105 (26%), Positives = 35/105 (33%), Gaps = 29/105 (27%)
Query: 61 RQRDPPADREGEREVLRGQRESPPPP------QLPPELLTNPSGSAIQSSPSRFRRVPAD 114
++ + D+EGE + R E P +LPP LT P+ S P
Sbjct: 368 KKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPP-------- 419
Query: 115 NAGPRRQLAKGVPLRPGAEPPAPASDPDLEPTPPGGLKSPPLPCA 159
P PP P P P P L SPP P A
Sbjct: 420 ---------------PSTSPPPPLCPPPPPPVSPPPLPSPPPPPA 449
Score = 30.8 bits (68), Expect = 0.85
Identities = 26/79 (32%), Positives = 28/79 (35%), Gaps = 12/79 (15%)
Query: 80 RESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAK-----------GVPL 128
RE PPPP PP A +S R + A P K G P
Sbjct: 616 RELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPE 675
Query: 129 RPGAEPPAPASDPDLEPTP 147
P EPP PA D EP P
Sbjct: 676 APEPEPP-PADDSPAEPEP 693
Score = 30.4 bits (67), Expect = 1.1
Identities = 35/137 (25%), Positives = 55/137 (40%), Gaps = 26/137 (18%)
Query: 22 PGTAPPPS-----CGRGPETPSRSQSPKLRRVAKVAGQLRRRRLRQRDPPADREGEREVL 76
P PPP GP +P R Q+ +++RV+ +G+ + P D +GE
Sbjct: 2251 PAPPPPPPPLTLVLSSGPASPPR-QAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEA--- 2306
Query: 77 RGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRV--------PA--DNAGPRRQLAKGV 126
S PQ+P L + S ++ R V PA ++ GP ++ + +
Sbjct: 2307 -----SEDTPQVPG--LGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLL 2359
Query: 127 PLRPGAEPPAPASDPDL 143
PL P P PDL
Sbjct: 2360 PLPEDGPPQVPDGPPDL 2376
Score = 29.3 bits (64), Expect = 2.5
Identities = 42/142 (29%), Positives = 53/142 (37%), Gaps = 20/142 (14%)
Query: 65 PPADREGEREVLRGQRESPPPPQLPPELLTNPSGSAIQSSPSRFRRVPADNAGPRRQLAK 124
PP G V+ R +PPPP PP L SG A S P + RV K
Sbjct: 2235 PPGPLLGVLPVVGVVRPAPPPPP-PPLTLVLSSGPA--SPPRQAIRV------------K 2279
Query: 125 GVPLRPGAEPPAPA--SDPDLEPTPPGGLKSPPLPCASGQGVPGTRRRQNKL-GVETLLL 181
V G PPAP P L+ +P +P G R + + GV L L
Sbjct: 2280 RVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGV--LDL 2337
Query: 182 RRPQLPPHSETFLPVLDSGTAL 203
RP P E+ P+ + L
Sbjct: 2338 DRPGEPAGEESPGPLQERSPLL 2359
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.134 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,819,354
Number of Sequences: 37866
Number of extensions: 897401
Number of successful extensions: 10630
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 257
Number of HSP's successfully gapped in prelim test: 1266
Number of HSP's that attempted gapping in prelim test: 6620
Number of HSP's gapped (non-prelim): 4205
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.