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Search of human proteins with 116268091
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116268091 PHD finger protein 23 [Homo sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116268091 PHD finger protein 23 [Homo sapiens] 833 0.0
gi|167466270 PHD finger protein 13 [Homo sapiens] 129 5e-30
gi|18034775 PHD finger protein 20 [Homo sapiens] 56 7e-08
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 55 1e-07
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 54 3e-07
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 53 4e-07
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 52 1e-06
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 51 2e-06
gi|169213924 PREDICTED: leucine rich repeat containing 68 [Homo ... 50 3e-06
gi|169214345 PREDICTED: leucine rich repeat containing 68 [Homo ... 50 3e-06
gi|169213302 PREDICTED: leucine rich repeat containing 68 [Homo ... 50 3e-06
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 50 4e-06
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 50 5e-06
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 50 5e-06
gi|151101459 SAPS domain family, member 1 [Homo sapiens] 50 5e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 48 1e-05
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 48 1e-05
gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 48 1e-05
gi|166795262 AE binding protein 2 isoform a [Homo sapiens] 48 1e-05
gi|145301567 hypothetical protein LOC56006 [Homo sapiens] 47 2e-05
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 47 2e-05
gi|145199237 transcription elongation factor B polypeptide 3 bin... 47 2e-05
gi|13376339 plasticity-related protein 2 [Homo sapiens] 47 4e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni... 47 4e-05
gi|38788260 bromodomain PHD finger transcription factor isoform ... 46 5e-05
gi|38788274 bromodomain PHD finger transcription factor isoform ... 46 5e-05
gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens] 46 5e-05
gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens] 46 5e-05
gi|31581524 cordon-bleu homolog [Homo sapiens] 46 7e-05
gi|215599585 integrator complex subunit 12 [Homo sapiens] 45 9e-05
>gi|116268091 PHD finger protein 23 [Homo sapiens]
Length = 403
Score = 833 bits (2151), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MLEAMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPAS 60
MLEAMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPAS
Sbjct: 1 MLEAMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPAS 60
Query: 61 GSSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQ 120
GSSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQ
Sbjct: 61 GSSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQ 120
Query: 121 APDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRK 180
APDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRK
Sbjct: 121 APDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRK 180
Query: 181 KDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQA 240
KDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQA
Sbjct: 181 KDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQA 240
Query: 241 PPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSES 300
PPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSES
Sbjct: 241 PPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSES 300
Query: 301 KEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCRKPFAGRPMIECSLCG 360
KEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCRKPFAGRPMIECSLCG
Sbjct: 301 KEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCRKPFAGRPMIECSLCG 360
Query: 361 TWIHLSCAKIKKTNVPDFFYCQKCKELRPEARRLGGPPKSGEP 403
TWIHLSCAKIKKTNVPDFFYCQKCKELRPEARRLGGPPKSGEP
Sbjct: 361 TWIHLSCAKIKKTNVPDFFYCQKCKELRPEARRLGGPPKSGEP 403
>gi|167466270 PHD finger protein 13 [Homo sapiens]
Length = 300
Score = 129 bits (324), Expect = 5e-30
Identities = 81/216 (37%), Positives = 111/216 (51%), Gaps = 46/216 (21%)
Query: 198 VLRRPRPTPG--DGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEE 255
+L+R +P+ D +K ++KK KKRK + D+D+ +E
Sbjct: 97 LLQRAKPSNFLLDRKKTDKLKKKKKRKRR-------------------DSDAPGKEGYRG 137
Query: 256 EEEEEEMATVVGGEAPVPVLPTPPEAPRPP--------------ATVHPEGVPPADSESK 301
+ E A P L P+AP P ATV P+ V +E K
Sbjct: 138 GLLKLEAADPYVETPTSPTLQDIPQAPSDPCSGWDSDTPSSGSCATVSPDQVKEIKTEGK 197
Query: 302 EV----GSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCRKPFAGRPMIECS 357
G +D D++ + DEDIMV+S DDSWDL+TC+C KPFAGRPMIEC+
Sbjct: 198 RTIVRQGKQVVFRDEDSTGN-------DEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECN 250
Query: 358 LCGTWIHLSCAKIKKTNVPDFFYCQKCKELRPEARR 393
C TWIHLSCAKI+K+NVP+ F CQKC++ + + RR
Sbjct: 251 ECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRR 286
Score = 74.7 bits (182), Expect = 1e-13
Identities = 58/149 (38%), Positives = 71/149 (47%), Gaps = 22/149 (14%)
Query: 20 ETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGSSSPLRGESAA-DSDGWD 78
E P KRRRT+EDFNKFC+FVLAYAGYIP KEE P S SP + DSDGWD
Sbjct: 14 EYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEE--LPLRSSPSPANSTAGTIDSDGWD 71
Query: 79 SAPSDLRTIQTFVKKAKSSKRRAAQAGPT--QPGPPRSTFSRLQAPDSATLLEKMKLKDS 136
+ SD+ + S R + PT Q P + + D +K K +DS
Sbjct: 72 AGFSDIASSVPL----PVSDRCFSHLQPTLLQRAKPSNFLLDRKKTDKLKKKKKRKRRDS 127
Query: 137 -----------LFDLDG--PKVASPLSPT 152
L L+ P V +P SPT
Sbjct: 128 DAPGKEGYRGGLLKLEAADPYVETPTSPT 156
>gi|18034775 PHD finger protein 20 [Homo sapiens]
Length = 1012
Score = 55.8 bits (133), Expect = 7e-08
Identities = 52/210 (24%), Positives = 85/210 (40%), Gaps = 41/210 (19%)
Query: 204 PTPGDGEKRS--------RIKKSKKRKLKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEE 255
PT D EK R+K KK+K KK + P+ P S+ E + +E
Sbjct: 520 PTTKDKEKNKEKKFKEFVRVKPKKKKKKKKKTK---------PECPCSE---EISDTSQE 567
Query: 256 EEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSESKEVGSTET------- 308
+ A G + P + P+ P + H V + ++ S+E+
Sbjct: 568 PSPPKAFAVTRCGSSHKPGVHMSPQLHGPESGHHKGKVKALEEDNLSESSSESFLWSDDE 627
Query: 309 -SQDGDASSSEGEMRVMDEDIMVESGDDSWD--LITCYCRKPFAGRPMIECSLCGTWIHL 365
QD D +++ DE++ GDD +D ++ C C MI+C C W H
Sbjct: 628 YGQDVDVTTNP------DEEL---DGDDRYDFEVVRCICEVQEENDFMIQCEECQCWQHG 678
Query: 366 SCAKIKKTNVPDFFYCQKCKELRPEARRLG 395
C + + NVP+ + C C++ P +R G
Sbjct: 679 VCMGLLEENVPEKYTCYVCQD--PPGQRPG 706
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 55.1 bits (131), Expect = 1e-07
Identities = 54/228 (23%), Positives = 80/228 (35%), Gaps = 52/228 (22%)
Query: 210 EKRSRIKKSKKRKLKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGE 269
EK+ K+ KK+K K+ E+ ++ + + E+ E+E+E+ + E++
Sbjct: 700 EKKKDKKEKKKKKEKEKEKKEK-------EREKEKREREKREKEKEKHKHEKIKVEPVAL 752
Query: 270 APVPVLP----------------------------------TPPEAPRP---PATVHPEG 292
AP PV+P TPP AP P P V P
Sbjct: 753 APSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSQNRPKTPPPAPAPAPGPMLVSPAP 812
Query: 293 VPPADSESKEVGSTETSQDGDASSSEGE----MRVMDEDIMVESGDDSWD---LITCYCR 345
VP G G A+S V+ E + D W I C
Sbjct: 813 VPLPLLAQAAAGPALLPSPGPAASGASAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCN 872
Query: 346 KPFAGRPMIECSLCGTWIHLSCAKIKKTNVPDF-FYCQKCKELRPEAR 392
KP G PMI C C W H C I + ++C KC + + +
Sbjct: 873 KPDDGSPMIGCDDCDDWYHWPCVGIMTAPPEEMQWFCPKCANKKKDKK 920
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 53.9 bits (128), Expect = 3e-07
Identities = 83/332 (25%), Positives = 120/332 (36%), Gaps = 59/332 (17%)
Query: 48 IPPSKEES----DWPASGSSSPLR----GESAADSDGWDSAPSDLRTIQTFVKKAKSSKR 99
+P ++EE +W + L+ G + S D P +LR + + +R
Sbjct: 530 VPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPE-----EGEER 584
Query: 100 RAAQAGPTQPGPPRSTFSRLQAPDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSR 159
R A PT PR + A + L L L DG + TS+
Sbjct: 585 RRLGAEPTVR--PRGRSMQALAEEDLQHLPPQPLPPQLSQGDGR-----------SETSQ 631
Query: 160 PPAALTPVPLSQGDLSHPPRKKDRKNRKLGP-----GAGAGFGVLRRPRPTP-----GDG 209
PP TP S L PR + R++ GP F V PR P D
Sbjct: 632 PP---TPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLSLPYQDF 688
Query: 210 EKRSRIKKSKKRKLKKAER---------GDRLP-PPGPPQAPPSDTDSEEEEEEEEEEEE 259
++ + + R L + R ++P P PQA + + EEEE+EEEEEE+
Sbjct: 689 KRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEED 748
Query: 260 EEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSESKEVG--STETSQDG----- 312
EE E E A E + P S E ST+ SQ+G
Sbjct: 749 EEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTL 808
Query: 313 ---DASSSEGEMRVMDEDIMVESGDDSWDLIT 341
D S G + D D+ E G + L++
Sbjct: 809 LADDQKESRGRASMADGDLEPEEGSKTLVLVS 840
Score = 36.2 bits (82), Expect = 0.054
Identities = 55/258 (21%), Positives = 81/258 (31%), Gaps = 48/258 (18%)
Query: 66 LRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQAPDSA 125
LR S A S + T+ + + A A P + G +T SR+ P
Sbjct: 1103 LRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATRSRIPRP--- 1159
Query: 126 TLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDRKN 185
L P + P S +H + P AL S+ L PP
Sbjct: 1160 ------------IGLRMPMPVAAQQPASRSHGAAP--ALDTAITSRLQLQTPP------- 1198
Query: 186 RKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQAPPSDT 245
G+ RP+ PG G R A+ G R P P P+ P S +
Sbjct: 1199 -------GSATAADLRPKQPPGRGLGPGR-----------AQAGARPPAPRSPRLPASTS 1240
Query: 246 DSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSESK---- 301
+ + + P +P P P PA P+G P K
Sbjct: 1241 AARNASASPRSQSLSRRESPSPSHQARPGVPPPRGVP--PARAQPDGTPSPGGSKKGPRG 1298
Query: 302 EVGSTETSQDGDASSSEG 319
++ + + G A +EG
Sbjct: 1299 KLQAQRATTKGRAGGAEG 1316
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 53.1 bits (126), Expect = 4e-07
Identities = 35/107 (32%), Positives = 50/107 (46%), Gaps = 6/107 (5%)
Query: 233 PPPGPPQAPPSDTDSEEEEEEEEEEE-EEEMATVVGGEAPVPVLPTPPEAPRPPATVHPE 291
P P P S T+ EEEEEEEEEEE EEE EAP P+ P P+P + +
Sbjct: 300 PKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSP-----PQPASPAEED 354
Query: 292 GVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWD 338
+PP D +++ +E ++ M+E I + S+D
Sbjct: 355 KMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFD 401
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 52.0 bits (123), Expect = 1e-06
Identities = 56/221 (25%), Positives = 86/221 (38%), Gaps = 33/221 (14%)
Query: 120 QAPDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHT-----SRPPAALTPVPLSQGDL 174
+APD TL + + S + + S ++ T S P A + V D
Sbjct: 897 EAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDS 956
Query: 175 SHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKL--------KKA 226
P + + K +K G +R +G K ++ KSK ++
Sbjct: 957 KEPIERPEEKPKKEG--------FIRS-----SEGPKPEKVYKSKSETRWGPRPSSNRRE 1003
Query: 227 ERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPV------LPTPPE 280
E DR P P D +EE E+ +E+E E+ V P LP PP
Sbjct: 1004 EVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPP 1063
Query: 281 APRPPATVHPEGV-PPADSESKEVGSTETSQDGDASSSEGE 320
P+PPA + P+ V PP E+++ STET+ S + E
Sbjct: 1064 PPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTE 1104
Score = 34.7 bits (78), Expect = 0.16
Identities = 63/308 (20%), Positives = 102/308 (33%), Gaps = 49/308 (15%)
Query: 50 PSKEESDWPASGSSSPLRGESAADSDGWDSAP-SDLRTIQTFVKKAKSSKRRAAQAGPTQ 108
P+ + PAS + +P+ ++A AP S ++ V + S+ + + P
Sbjct: 1778 PASTSAPVPAS-TLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPAS 1836
Query: 109 PGPPRSTFSRLQAPDSATLLEKMK-------LKDSLFDLDGPKVASPLSPTSLTHTSRPP 161
P + + P S T+L L + P +SP +P T
Sbjct: 1837 APAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPAS 1896
Query: 162 AALTPVPLSQGDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKR 221
A VPL+ S P A A V P + +++ K +
Sbjct: 1897 APTASVPLAPASASAP--------------APAPTPVSAPNPAPPAPAQTQAQTHKPVQN 1942
Query: 222 KLKKAERGDRLPPPG---PPQAPPSDTDSEEEEEEEEEEEEEEMATVV---GGEAPVPVL 275
L+ + + PPP P P+ TD + + + T AP VL
Sbjct: 1943 PLQTTSQSSKQPPPSIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVL 2002
Query: 276 P---------TPPEAPRPPATVHP----------EGVPPADSESKEVGSTETSQDGDASS 316
+PP+ P A P EG E+G T+T Q G +S
Sbjct: 2003 NDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEIG-TDTIQFGAPAS 2061
Query: 317 SEGEMRVM 324
+ E V+
Sbjct: 2062 NGNENEVV 2069
Score = 28.9 bits (63), Expect = 8.6
Identities = 20/90 (22%), Positives = 37/90 (41%), Gaps = 3/90 (3%)
Query: 178 PRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGP 237
P+++ +K + GP L P K I K + K +K + ++ P G
Sbjct: 2083 PKEQRQKQPRAGPIKAQKLPDLS---PVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQ 2139
Query: 238 PQAPPSDTDSEEEEEEEEEEEEEEMATVVG 267
+ P+ S + +E + EM+T +G
Sbjct: 2140 EKPSPATVRSTDPVTTKETKAVSEMSTEIG 2169
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 51.2 bits (121), Expect = 2e-06
Identities = 74/292 (25%), Positives = 102/292 (34%), Gaps = 50/292 (17%)
Query: 49 PPSKEESDWPASGSSSPLRGESAADS--DGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGP 106
PP KE + + P G A G P R +T + P
Sbjct: 880 PPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPP 939
Query: 107 TQPGPPRSTFSRLQAPDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTP 166
+PG P ++ P T +E++ K + PK P P +T TP
Sbjct: 940 EEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKP-DPLKITKGKLGGPKETP 998
Query: 167 VPLSQGDLSHPPR-KKDRKNRKLGPGAGAGFG---VLRRPRPTPGDGEKRSRIKKSKKRK 222
G+LS PR ++D ++GP + G G R R G R R +S++ +
Sbjct: 999 ---PNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFR 1055
Query: 223 LKKAERGD--RLPPPGPPQAPP-------SDTDSEEEEEEEEEEEEEEMATVVGGE---- 269
+ RGD R G P PP S+T SE E EE + + + G E
Sbjct: 1056 SYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHES 1115
Query: 270 --------AP---------VPVLPTPPEAPRPPATVH----------PEGVP 294
AP VP+ P PP AP PA P GVP
Sbjct: 1116 DLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVP 1167
Score = 42.0 bits (97), Expect = 0.001
Identities = 94/388 (24%), Positives = 130/388 (33%), Gaps = 93/388 (23%)
Query: 13 PPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEE-SDWPASGSSSPLR---- 67
PPP + P PP K + G +PPSKE + G SP+
Sbjct: 1177 PPPQVCPGWSPPAKSLAPKKP----------PTGPLPPSKEPLKEKLIPGPLSPVARGGS 1226
Query: 68 --GESAADSDG-------------WDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQ-PGP 111
G + DG D P R Q A+ S+ + + P PGP
Sbjct: 1227 NGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGP 1286
Query: 112 PRSTFSRLQAPDSATLLEKMK-LKDSLFDLDGPKVASPLSPTSLTHTSR------PPAAL 164
+ + AP K L + D + + + T R PP L
Sbjct: 1287 EEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLL 1346
Query: 165 TP-------------VP----LSQGDLSHPPRKKD--------------RKNRKLGPGAG 193
TP VP +S+GDLS R KD R+NR+ GPG
Sbjct: 1347 TPKAVGTPGGGGGGAVPGISAMSRGDLSQ--RAKDLSKRSFSSQRPGMERQNRRPGPGGK 1404
Query: 194 AGF--------GVLRRPRPTPGDGEKRS-RIKKSKKRKLKKAERGDRLPPPGP------- 237
AG G R PG G+KRS K++ R ++ G LPPP P
Sbjct: 1405 AGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFR 1464
Query: 238 -PQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPE--APRPPATVHPEGVP 294
Q S+ ++ + + + G P LP P+ +PRPP P+ V
Sbjct: 1465 LDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVN 1524
Query: 295 ---PADSESKEVGSTETSQDGDASSSEG 319
+D +E G G S G
Sbjct: 1525 SGLSSDPHFEEPGPMVRGVGGTPRDSAG 1552
Score = 41.6 bits (96), Expect = 0.001
Identities = 69/337 (20%), Positives = 108/337 (32%), Gaps = 76/337 (22%)
Query: 3 EAMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGS 62
E P E PP KP PP + + PP D+P G
Sbjct: 394 ETSRPPETEPGPPAPKPPLPPPHRGPA---------------GNWGPPG----DYPDRGG 434
Query: 63 SSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQAP 122
P + + D D + + ++ K S + A R+Q
Sbjct: 435 P-PCKPPAPEDED------------EAWRQRRKQSSSEISLAVERARRRREEEERRMQEE 481
Query: 123 DSATLLEKMKLKDSLFDLDGPKV-ASPLSPTSLTHTSRPPAALT---PVPLSQGDLSHPP 178
A EK+K D F ++ A P +P + T PP A+ P P + S P
Sbjct: 482 RRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPT 541
Query: 179 RKKDRKNRKLGPGAGAGF--GVLRRPRPTPGDGEKRSRIKKSKKRK--------LKKAER 228
+ + + P A + GV P G G S S + + E
Sbjct: 542 PETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEP 601
Query: 229 GDRLPPP---------------GPPQAPPSD---------------TDSEEEEEEEEEEE 258
+ +PPP GP + PPS ++E+ +++++
Sbjct: 602 PEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQ 661
Query: 259 EEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPP 295
+ G P PV P+PP+ A P+ PP
Sbjct: 662 HQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPP 698
Score = 37.4 bits (85), Expect = 0.024
Identities = 48/198 (24%), Positives = 59/198 (29%), Gaps = 39/198 (19%)
Query: 141 DGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDRKNRKLGPGAGAGFGVLR 200
+ P P T+ TSRPP P + L P R G G +
Sbjct: 379 NSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCK 438
Query: 201 RPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEE 260
P P D R R K+S ER R EEEE +EE
Sbjct: 439 PPAPEDEDEAWRQRRKQSSSEISLAVERARR----------------RREEEERRMQEER 482
Query: 261 EMATV----------------VGGEAPVPVLPTPPEAPRPPATV-----HPEGVPPADSE 299
A + E P P P P PP V P PPA +
Sbjct: 483 RAACAEKLKRLDEKFGAPDKRLKAEPAAP--PAAPSTPAPPPAVPKELPAPPAPPPASAP 540
Query: 300 SKEVGSTETSQDGDASSS 317
+ E E +Q A S+
Sbjct: 541 TPETEPEEPAQAPPAQST 558
Score = 35.0 bits (79), Expect = 0.12
Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 31/145 (21%)
Query: 160 PPAALTPVPLSQ--GDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRI-K 216
PP PVP + GD P R+ P G G+ ++ P +++ ++ K
Sbjct: 606 PPPTTPPVPKVEPKGDGIGPTRQP--------PSQGLGYPKYQKSLPPRFQRQQQEQLLK 657
Query: 217 KSKKRKLKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLP 276
+ ++ + ++ ++G P P PP P T + V +AP P
Sbjct: 658 QQQQHQWQQHQQGSAPPTPVPPSPPQPVT----------------LGAVPAPQAP----P 697
Query: 277 TPPEAPRPPATVHPEGVPPADSESK 301
PP+A P A P +PP + + +
Sbjct: 698 PPPKALYPGALGRPPPMPPMNFDPR 722
Score = 30.8 bits (68), Expect = 2.3
Identities = 55/228 (24%), Positives = 82/228 (35%), Gaps = 34/228 (14%)
Query: 130 KMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDRKNR-KL 188
+M DS DL G S +S + S P L +G PP++ +
Sbjct: 1645 EMSQSDSGVDLSGD---SQVSSGPCSQRSSPDGGL------KGAAEGPPKRPGGSSPLNA 1695
Query: 189 GPGAGA-GFGVLRRPRPTPGDGEKRSRIKKSK-------KRKLKKAERGDRLPP------ 234
P G G RRP P P DG+++ ++ + ++ +RG P
Sbjct: 1696 VPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHR 1755
Query: 235 PGPP-QAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEG- 292
PGPP Q SD DS+ + + E+ T EA +PV P A+ P+
Sbjct: 1756 PGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEA-IPVSRDWELLPSAAASAEPQSK 1814
Query: 293 -------VPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESG 333
VP S + + SSS+ MD + SG
Sbjct: 1815 NLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSG 1862
Score = 29.6 bits (65), Expect = 5.1
Identities = 26/99 (26%), Positives = 31/99 (31%), Gaps = 4/99 (4%)
Query: 229 GDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPR----P 284
G+ PP + S + E T G AP P LP P P P
Sbjct: 366 GEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGP 425
Query: 285 PATVHPEGVPPADSESKEVGSTETSQDGDASSSEGEMRV 323
P G PP + E Q SSSE + V
Sbjct: 426 PGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAV 464
>gi|169213924 PREDICTED: leucine rich repeat containing 68 [Homo
sapiens]
Length = 625
Score = 50.4 bits (119), Expect = 3e-06
Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 9/117 (7%)
Query: 227 ERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATV----VGGEAPVPVLPTPPEAP 282
+ G P P P SD+D EEEEEEE E +E + G P P P P
Sbjct: 506 QNGAPSPAPSPDSDSDSDSDGEEEEEEEGERDETPSGAIDTRDTGSSEPQPPPEPPRSGP 565
Query: 283 RPPATVHPE---GVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDS 336
P + PE +PP EV + + S S+ E + E++++E+ +S
Sbjct: 566 PLPNGLKPEFALALPPEPPPGPEVKGGSCGLEHELSCSKNEKEL--EELLLEASQES 620
>gi|169214345 PREDICTED: leucine rich repeat containing 68 [Homo
sapiens]
Length = 625
Score = 50.4 bits (119), Expect = 3e-06
Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 9/117 (7%)
Query: 227 ERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATV----VGGEAPVPVLPTPPEAP 282
+ G P P P SD+D EEEEEEE E +E + G P P P P
Sbjct: 506 QNGAPSPAPSPDSDSDSDSDGEEEEEEEGERDETPSGAIDTRDTGSSEPQPPPEPPRSGP 565
Query: 283 RPPATVHPE---GVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDS 336
P + PE +PP EV + + S S+ E + E++++E+ +S
Sbjct: 566 PLPNGLKPEFALALPPEPPPGPEVKGGSCGLEHELSCSKNEKEL--EELLLEASQES 620
>gi|169213302 PREDICTED: leucine rich repeat containing 68 [Homo
sapiens]
Length = 625
Score = 50.4 bits (119), Expect = 3e-06
Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 9/117 (7%)
Query: 227 ERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATV----VGGEAPVPVLPTPPEAP 282
+ G P P P SD+D EEEEEEE E +E + G P P P P
Sbjct: 506 QNGAPSPAPSPDSDSDSDSDGEEEEEEEGERDETPSGAIDTRDTGSSEPQPPPEPPRSGP 565
Query: 283 RPPATVHPE---GVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDS 336
P + PE +PP EV + + S S+ E + E++++E+ +S
Sbjct: 566 PLPNGLKPEFALALPPEPPPGPEVKGGSCGLEHELSCSKNEKEL--EELLLEASQES 620
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 50.1 bits (118), Expect = 4e-06
Identities = 83/359 (23%), Positives = 128/359 (35%), Gaps = 63/359 (17%)
Query: 8 PSPEDPPPTLKPETQPPEKRRRTIEDFNKFC-----SFVLAYAGYIPPSKEESDWPASGS 62
PS PPP P K ++ + K+C + V G +P + + S P SG+
Sbjct: 787 PSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTT-QYSPGPPSGA 845
Query: 63 SSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAA-------QAGPTQPGPPRST 115
++ L SAA S PS + Q ++ R A PTQP PP S
Sbjct: 846 TA-LPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSL 904
Query: 116 FSRLQAPDSATLLEKMKLKDSLFDLDGPKVASPLSPT-------SLTHTSRPPAALTP-- 166
+S L E + ++L + G P P S T PPA
Sbjct: 905 PPARS--ESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEA 962
Query: 167 --VPLSQGDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLK 224
V G ++ +++R+ G RRPR G + ++++ K K R++
Sbjct: 963 GGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVG--RRPRE--GRAKAKAKVPKEKSRRVL 1018
Query: 225 KAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRP 284
+ D + EE + E+ ++ +A P P PP AP P
Sbjct: 1019 ------------------GNLDLQSEEIQGREKSRPDLGGA--SKAKPPTAPAPPSAPAP 1058
Query: 285 PATVHPEGVPPADSESKEVGSTETSQDGDASSSEGEMRVMDED---------IMVESGD 334
A P P A K+ G + + ++R + E I VESGD
Sbjct: 1059 SAQPTP---PSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELKIRLIKVESGD 1114
Score = 30.0 bits (66), Expect = 3.9
Identities = 69/319 (21%), Positives = 96/319 (30%), Gaps = 45/319 (14%)
Query: 23 PPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGSSSPLRGESAADSDGWDSAPS 82
PPE++ + + + AY + P + P P ES S
Sbjct: 299 PPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGS 358
Query: 83 DLRTIQTFVKKAKSSKRRAAQ------AGPTQPGPPRSTFSRLQAPDSATLLEKMKLKDS 136
DLR + + SS AA A PG P +T S + S T L ++
Sbjct: 359 DLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPG 418
Query: 137 LFDLD---------------GPKVASPL-----SPTSLTHTSRPPAALTPVPLSQGDLSH 176
+ D GP S +P + H S PP +P P L
Sbjct: 419 IPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLR 478
Query: 177 PPRKKDRKNRKLGPGAGAG-----------FGVLRRPRPTPGDGEKRSRIKKSKKRKLKK 225
PP GP A FG PRP P R +
Sbjct: 479 PPPPPAWLK---GPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSV 535
Query: 226 AERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMAT---VVGGEAPVPVLPTPPEAP 282
+ D PP PP S ++S + P+P P+P + P
Sbjct: 536 GTQ-DSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNP 594
Query: 283 R-PPATVHPEGVPPADSES 300
+ PP +PPA S
Sbjct: 595 QDPPLVPLTLALPPAPPSS 613
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 49.7 bits (117), Expect = 5e-06
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 7/103 (6%)
Query: 283 RPPATVHPEGVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITC 342
RPP T P PP+ SK T+ + D +SS + E G D+ C
Sbjct: 69 RPPPTP-PASPPPSVLISKNEVGIFTTPNFDETSSATTISTS------EDGSYGTDVTRC 121
Query: 343 YCRKPFAGRPMIECSLCGTWIHLSCAKIKKTNVPDFFYCQKCK 385
C MI C C W H+ C I + ++PD + C++C+
Sbjct: 122 ICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQ 164
Score = 35.8 bits (81), Expect = 0.071
Identities = 40/178 (22%), Positives = 58/178 (32%), Gaps = 30/178 (16%)
Query: 3 EAMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGS 62
E M +P PE+P PT E P+ + T + PP + P S
Sbjct: 1320 ELMEDPDPENPEPTTTNECPSPDTSQNTCKS---------------PPKMSKPGSPGSVI 1364
Query: 63 SSPLRGESAADSD-GWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQA 121
+ G+ D WDS S +A++ + Q S+
Sbjct: 1365 PAQAHGKIFTKPDPQWDSTVS--------ASEAENGVHLKTELQQKQLSNNNQALSKNHP 1416
Query: 122 PDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTP-VPLSQGDLSHPP 178
P + +L L P V + L H PP + TP P+ G LS P
Sbjct: 1417 PQTHVRNSSEQLSQKL-----PSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKP 1469
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 49.7 bits (117), Expect = 5e-06
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 7/103 (6%)
Query: 283 RPPATVHPEGVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITC 342
RPP T P PP+ SK T+ + D +SS + E G D+ C
Sbjct: 69 RPPPTP-PASPPPSVLISKNEVGIFTTPNFDETSSATTISTS------EDGSYGTDVTRC 121
Query: 343 YCRKPFAGRPMIECSLCGTWIHLSCAKIKKTNVPDFFYCQKCK 385
C MI C C W H+ C I + ++PD + C++C+
Sbjct: 122 ICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQ 164
Score = 35.8 bits (81), Expect = 0.071
Identities = 40/178 (22%), Positives = 58/178 (32%), Gaps = 30/178 (16%)
Query: 3 EAMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGS 62
E M +P PE+P PT E P+ + T + PP + P S
Sbjct: 1320 ELMEDPDPENPEPTTTNECPSPDTSQNTCKS---------------PPKMSKPGSPGSVI 1364
Query: 63 SSPLRGESAADSD-GWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQA 121
+ G+ D WDS S +A++ + Q S+
Sbjct: 1365 PAQAHGKIFTKPDPQWDSTVS--------ASEAENGVHLKTELQQKQLSNNNQALSKNHP 1416
Query: 122 PDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTP-VPLSQGDLSHPP 178
P + +L L P V + L H PP + TP P+ G LS P
Sbjct: 1417 PQTHVRNSSEQLSQKL-----PSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKP 1469
>gi|151101459 SAPS domain family, member 1 [Homo sapiens]
Length = 881
Score = 49.7 bits (117), Expect = 5e-06
Identities = 33/87 (37%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 228 RGDRL-PPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTP-PEAPRPP 285
RG RL PPG +D++ EEEE+EEEEE+EE + G A P+P P+ P P
Sbjct: 652 RGARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPS 711
Query: 286 ATVHPEGVPPADSESKEVGSTETSQDG 312
T + VP S V E G
Sbjct: 712 WTATFDPVPTDAPTSPRVSGEEELHTG 738
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 48.1 bits (113), Expect = 1e-05
Identities = 63/321 (19%), Positives = 111/321 (34%), Gaps = 61/321 (19%)
Query: 9 SPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGSSSPLRG 68
S ++PP KP+ P + +T PP PA + G
Sbjct: 175 SEDEPPKNQKPKITPVTVKAQT----------------KAPPK------PARAAPKIANG 212
Query: 69 ESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQAPDSATLL 128
++A+ S S+ S + S+ A A P + P + ++ + T
Sbjct: 213 KAASSSSSSSSSSS-----------SDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPT 261
Query: 129 EKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDRKNRKL 188
K + + + P+ ++S PP + P S G + PP+K K + +
Sbjct: 262 RKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLG--TQPPKKAVEKQQPV 319
Query: 189 GPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQAPPSDTDSE 248
+ E S ++ KK K PP +A S +DS
Sbjct: 320 ESSEDSS-------------DESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSS 366
Query: 249 EEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSESKEVGSTE- 307
+ + E++E + P T + +P T V PA + + VG +
Sbjct: 367 DSDSSEDDEAPSK-----------PAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQK 415
Query: 308 -TSQDGDASSSEGEMRVMDED 327
++ D+SSSE E +E+
Sbjct: 416 LLTRKADSSSSEEESSSSEEE 436
Score = 45.4 bits (106), Expect = 9e-05
Identities = 60/273 (21%), Positives = 95/273 (34%), Gaps = 34/273 (12%)
Query: 48 IPPSKEESDWPASGSSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPT 107
+P + + P +++P R S+++ D KK +K + P
Sbjct: 243 VPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQ--------KKPMKNKPGPYSSVPP 294
Query: 108 QPGPPRSTFSRLQAPDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPV 167
PP Q P A +EK + +S D +S S +S +PP T
Sbjct: 295 PSAPPPKKSLGTQPPKKA--VEKQQPVESSED------SSDESDSSSEEEKKPP---TKA 343
Query: 168 PLSQGDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAE 227
+S+ PP KK ++ + + +P ++ + K K
Sbjct: 344 VVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPA 403
Query: 228 RGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPAT 287
+ P G + DS EEE EEE+ +V T P+A A
Sbjct: 404 AAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVA--------TTKPKATAKAAL 455
Query: 288 VHPEGVPPADSESKEVGSTETSQDGDASSSEGE 320
P P GS ++S D D+SSSE E
Sbjct: 456 SLPAKQAPQ-------GSRDSSSDSDSSSSEEE 481
Score = 37.0 bits (84), Expect = 0.032
Identities = 62/302 (20%), Positives = 114/302 (37%), Gaps = 34/302 (11%)
Query: 8 PSPEDPPPTLKPETQPPEK---RRRTIEDFNKFC--SFVLAYAGYIPPSKEESDWPASGS 62
P P PPP TQPP+K +++ +E S + PP+K A+
Sbjct: 293 PPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVS-KATTK 351
Query: 63 SSPLR--GESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQ 120
P + ES++DS DS+ D + K A ++K + + T P + +
Sbjct: 352 PPPAKKAAESSSDSSDSDSSEDD----EAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPK 407
Query: 121 APDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRK 180
P +K+ + + D S + T + A P ++ LS P ++
Sbjct: 408 QPVGGG--QKLLTRKA----DSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQ 461
Query: 181 KDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQA 240
+ +R + + + + E+ K + K+K +K G P +
Sbjct: 462 APQGSRDSSSDSDS----------SSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKK 511
Query: 241 PPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSES 300
+++ + ++ EEEEE++ G +P P P+A A G +SE
Sbjct: 512 GKAESSNSSSSDDSSEEEEEKLK---GKGSP---RPQAPKANGTSALTAQNGKAAKNSEE 565
Query: 301 KE 302
+E
Sbjct: 566 EE 567
Score = 34.7 bits (78), Expect = 0.16
Identities = 31/147 (21%), Positives = 54/147 (36%), Gaps = 7/147 (4%)
Query: 173 DLSHPPRKK---DRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERG 229
++ PP KK K L PG A D + KK +K K +
Sbjct: 96 EVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAK 155
Query: 230 DRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVH 289
PP ++ SD+DS E+E + ++ + V + P P A P +
Sbjct: 156 AAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAP----PKPARAAPKIAN 211
Query: 290 PEGVPPADSESKEVGSTETSQDGDASS 316
+ + S S S ++ ++ A++
Sbjct: 212 GKAASSSSSSSSSSSSDDSEEEKAAAT 238
Score = 30.0 bits (66), Expect = 3.9
Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 16/103 (15%)
Query: 223 LKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAP 282
LK A+ +R P A + + + E+ EEEEE+ +A VP
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRV----- 112
Query: 283 RPPATVHPEGVPP--ADSESKEVGSTETSQDGDASSSEGEMRV 323
G+PP A +++ E S+E S D D + + V
Sbjct: 113 ---------GLPPGKAAAKASESSSSEESSDDDDEEDQKKQPV 146
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 48.1 bits (113), Expect = 1e-05
Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 11/105 (10%)
Query: 234 PPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGV 293
PP P + + EEEEEEE EEEEEE + V GE P P P + +
Sbjct: 305 PPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASP-----------AEEDKM 353
Query: 294 PPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWD 338
PP D +++ +E ++ M+E I + S+D
Sbjct: 354 PPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFD 398
>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
Length = 517
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/128 (32%), Positives = 50/128 (39%), Gaps = 15/128 (11%)
Query: 223 LKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVV------------GGEA 270
L++ R LPP P A + EEEEEEEEEEEE A V GG
Sbjct: 11 LEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGG 70
Query: 271 PVPVLPTPPEAPRPPATVHPEGVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMV 330
V E P+ PE A + E E +D +SS GE E ++
Sbjct: 71 GGGVGGGEAETMSEPS---PESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVG 127
Query: 331 ESGDDSWD 338
SG S D
Sbjct: 128 SSGGSSSD 135
>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
Length = 503
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/128 (32%), Positives = 50/128 (39%), Gaps = 15/128 (11%)
Query: 223 LKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVV------------GGEA 270
L++ R LPP P A + EEEEEEEEEEEE A V GG
Sbjct: 11 LEELSRLSPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGG 70
Query: 271 PVPVLPTPPEAPRPPATVHPEGVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMV 330
V E P+ PE A + E E +D +SS GE E ++
Sbjct: 71 GGGVGGGEAETMSEPS---PESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVG 127
Query: 331 ESGDDSWD 338
SG S D
Sbjct: 128 SSGGSSSD 135
>gi|145301567 hypothetical protein LOC56006 [Homo sapiens]
Length = 520
Score = 47.4 bits (111), Expect = 2e-05
Identities = 35/119 (29%), Positives = 51/119 (42%), Gaps = 15/119 (12%)
Query: 182 DRKNRKLGPGAG-----AGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKK---------AE 227
+R+ R PG+G +G G R P + E+R +++ ++K AE
Sbjct: 15 ERRRRWKEPGSGGPQNLSGPGGRERDYIAPWERERRDASEETSTSVMQKTPIILSKPPAE 74
Query: 228 RGDRLPPPGPPQAPPSDTDSEEE-EEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPP 285
R + PPP P APP+ E+ + EE + V G P P PP AP PP
Sbjct: 75 RSKQPPPPTAPAAPPAPAPLEKPIVLMKPREEGKGPVAVTGASTPEGTAPPPPAAPAPP 133
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 47.4 bits (111), Expect = 2e-05
Identities = 87/334 (26%), Positives = 129/334 (38%), Gaps = 60/334 (17%)
Query: 7 EPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGSSSPL 66
EP E L +TQ R R + + + F L G P S D PA S+ L
Sbjct: 1589 EPPREALTGELLLQTQQRRHRLRGLRNLSAFSERTL---GLGPLSFTLEDEPAL--STAL 1643
Query: 67 RGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQAPDSAT 126
+ +++G + P + V+K S A G T+ GP + F D
Sbjct: 1644 GSQLGEEAEGEEFCPCE-----ACVRKKVSPMSPKATMGATR-GPIKEAF------DLQQ 1691
Query: 127 LLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDRKNR 186
+L++ + + + DG A+ ++P THT P + V ++G L
Sbjct: 1692 ILQRKRGEHT----DGE--AAEVAPGK-THTD--PTSTRTVQGAEGGL------------ 1730
Query: 187 KLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQAPPSDTD 246
GPG G GV DGE R+ + K KL +AE GD + + S+T
Sbjct: 1731 --GPGLSQGPGV-----DEGEDGEGSQRLNRDKDPKLGEAE-GDAMAQEREGKTHNSETS 1782
Query: 247 SEEEEEEEEEEEE--EEMATVVG----------GEAPVPVLPTPPEAPRPPATVHPEGVP 294
+ E E E+E E E G GEA P ++ PE
Sbjct: 1783 AGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEG 1842
Query: 295 PADSESKEVGSTETSQDGDASSSEGEMRVMDEDI 328
A ES+ V + E +GDA +EGE + ED+
Sbjct: 1843 EAQPESEGVEAPEA--EGDAQEAEGEAQPESEDV 1874
Score = 37.0 bits (84), Expect = 0.032
Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 6/104 (5%)
Query: 229 GDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEA-PVPVLPTPPEA-----P 282
G+ P +AP ++ D++E E E + E E+ A GEA P PEA P
Sbjct: 1842 GEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQP 1901
Query: 283 RPPATVHPEGVPPADSESKEVGSTETSQDGDASSSEGEMRVMDE 326
PE A E++ V + ET + + S E + +E
Sbjct: 1902 ESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE 1945
Score = 33.5 bits (75), Expect = 0.35
Identities = 30/111 (27%), Positives = 45/111 (40%), Gaps = 11/111 (9%)
Query: 229 GDRLPPPGPPQAPPSDTDSEEEEEEEEEEE---------EEEMATVVGGEAPVPVLPTPP 279
G+ P +AP ++ + +E EEE + E E E A V GE P
Sbjct: 1991 GEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP 2050
Query: 280 EAPRPPATVHPEGVPPADSESKEV--GSTETSQDGDASSSEGEMRVMDEDI 328
E+ A E A+ E +E + S+D DA +EGE + E +
Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGV 2101
Score = 33.1 bits (74), Expect = 0.46
Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 9/106 (8%)
Query: 229 GDRLPPPGPPQAPPSDTDSEEEEE--EEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPA 286
G+ P +AP ++ +++ E E E E E E G EAP PE A
Sbjct: 1865 GEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEA 1924
Query: 287 TVHPEGVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVES 332
+ EG +SE E +Q+ + ++ E E + E ++ES
Sbjct: 1925 -LETEGEDEPESEGAE------AQEAEEAAQEAEGQTQPESEVIES 1963
Score = 32.3 bits (72), Expect = 0.78
Identities = 32/135 (23%), Positives = 53/135 (39%), Gaps = 11/135 (8%)
Query: 205 TPGDGEKRSR-IKKSKKRKLKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMA 263
T GD + S ++ + + + G+ G D D++E E E + E E A
Sbjct: 2044 TEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEA 2103
Query: 264 TVVGGEAPVPVLPTPPEAPRPPATVHP--EGVPPADSESKEVGSTETSQDG-DASSSEGE 320
GEA EAP P EG+ ++E G + +G +A +EGE
Sbjct: 2104 PEAEGEAQ---KAEGIEAPETEGEAQPESEGIEAPEAE----GEAQPESEGVEAQDAEGE 2156
Query: 321 MRVMDEDIMVESGDD 335
+ E I + ++
Sbjct: 2157 AQPESEGIEAQEAEE 2171
Score = 32.0 bits (71), Expect = 1.0
Identities = 27/114 (23%), Positives = 46/114 (40%), Gaps = 6/114 (5%)
Query: 225 KAERGDRLPPPGPPQAPPSDTDSEEEEEEE--EEEEEEEMATVVGGEAPVPVLPTPPEAP 282
+A ++ P +T+ E+E E E E +E EE A G+ +
Sbjct: 1907 EAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEA 1966
Query: 283 RPPATVHPEGVPP----ADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVES 332
A E V +++ E + S+D +A +EGEM+ +E+ ES
Sbjct: 1967 EEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPES 2020
Score = 30.8 bits (68), Expect = 2.3
Identities = 34/106 (32%), Positives = 49/106 (46%), Gaps = 14/106 (13%)
Query: 229 GDRLPPPGPPQAPPSDTDSEEEEE--EEEEEEEEEMATVVGGEAPVPVLPTPP-----EA 281
G+ P +A ++ +++ E E E +E EEE + G EAP P EA
Sbjct: 2139 GEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEA 2198
Query: 282 PRPPATVHP--EGV--PPADSESK-EVGSTETSQ-DGDAS-SSEGE 320
P P EGV P A+ E++ E ET + +G+A SEGE
Sbjct: 2199 PEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGE 2244
Score = 28.9 bits (63), Expect = 8.6
Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 11/81 (13%)
Query: 239 QAPPSDTDSEEEEE--EEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPA 296
+AP ++ +++ E E E E E E + G EAP PE PEGV
Sbjct: 2181 EAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPE---------PEGVETP 2231
Query: 297 DSESKEVGSTETSQDGDASSS 317
++E + +E G+ S
Sbjct: 2232 EAEGEAQPESEGETQGEKKGS 2252
>gi|145199237 transcription elongation factor B polypeptide 3
binding protein 1 [Homo sapiens]
Length = 1221
Score = 47.4 bits (111), Expect = 2e-05
Identities = 74/326 (22%), Positives = 114/326 (34%), Gaps = 56/326 (17%)
Query: 49 PPSKEESDWPASGSSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAG--P 106
PPSKE + A G E+A D D P K A ++ +++Q G P
Sbjct: 321 PPSKEGLE--AEGGGLRETKETAVQCDVGDLQPPP-------AKPASPAQVQSSQDGGCP 371
Query: 107 TQPGPPRSTFSRLQAP---DSATLLEKMK-------LKDSLFDLDGPKVASPLSPTSLTH 156
+ P + AP D A +K K ++ D GP+ +SP
Sbjct: 372 KEGKPKKKKTGAPPAPSCKDGAQGKDKTKDKGRGRPVEKPRADKKGPQASSPRRKAERPE 431
Query: 157 -TSRPPAALTPVPLS-QGDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSR 214
T + P++ TPV S +G P R+ + P AG G PRP K ++
Sbjct: 432 GTKKKPSSATPVATSGKGRPDRPARRPSPTSGDSRPAAGRG-----PPRPLQLPDRKSTK 486
Query: 215 IK---------------------KSKKRKLKKA-----ERGDRLPPPGPPQAPPSDTDSE 248
K KKR L A E D PG P PS S
Sbjct: 487 APSGKLVERKARSLDEGASQDAPKLKKRALSHADLFGDESEDEAAGPGVPSVWPSALPSL 546
Query: 249 EEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSESKEVGSTET 308
+ + + + G P + +PP +P P ++ + + + E
Sbjct: 547 SSDSDSDSDSSLGFPEAQG--PPKRLKASPPPSPAPSSSSSSSSSTSSAGADVDYSALEK 604
Query: 309 SQDGDASSSEGEMRVMDEDIMVESGD 334
D D+ E +R+ +E V++ D
Sbjct: 605 EVDFDSDPMEECLRIFNESTSVKTED 630
Score = 30.0 bits (66), Expect = 3.9
Identities = 42/178 (23%), Positives = 64/178 (35%), Gaps = 23/178 (12%)
Query: 151 PTSLTHTSRPPAALTPVPLSQGD---------LSHPPRKKDRKNRKLGPGAGAGFGVLRR 201
PT L + P + + L +G L + P+ + R P + V
Sbjct: 167 PTPLAAPAEPGSKYSLASLDRGQGRGGGGGGALEYVPKAVSQPRRHSRPVPSGKYVVDNS 226
Query: 202 PRPTPGDGEKRSRIK-------KSKKRKLKKAERGDRLPPPGPPQAPPSDTDSEEEEEEE 254
PT + + S S+ + K RG R P P AP D +
Sbjct: 227 RPPTDLEYDPLSNYSARHLSRASSRDERAAKRPRGSRGSEPYTP-APKKLCDPFGSCDAR 285
Query: 255 EEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADS--ESKEVGSTETSQ 310
+ E+E ATV G E P + P+A P + G PP+ E++ G ET +
Sbjct: 286 FSDSEDEAATVPGNE---PTTASTPKARADP-EIKATGQPPSKEGLEAEGGGLRETKE 339
>gi|13376339 plasticity-related protein 2 [Homo sapiens]
Length = 746
Score = 46.6 bits (109), Expect = 4e-05
Identities = 37/102 (36%), Positives = 45/102 (44%), Gaps = 17/102 (16%)
Query: 206 PGDGEKRSRIKKSKKRKLKKAERGDRLPP---PGPPQAPPSDTDSEEEEEEEEEEEEEEM 262
P D + ++ K+K + RG LP PG +AP EEEEEE+EEEEEEE
Sbjct: 426 PLDASRSKQLISEWKQKSLEG-RGLGLPDDASPGHLRAPAEPMAEEEEEEEDEEEEEEEE 484
Query: 263 ATVVGGEAPVPVLPT-------------PPEAPRPPATVHPE 291
G AP + PT PP A PP PE
Sbjct: 485 EEEDEGPAPPSLYPTVQARPGLGPRVILPPRAGPPPLVHIPE 526
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 46.6 bits (109), Expect = 4e-05
Identities = 73/314 (23%), Positives = 107/314 (34%), Gaps = 47/314 (14%)
Query: 13 PPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGSSSPLRGESAA 72
P P+L P PP ++ + + P + + P S + S
Sbjct: 735 PSPSLPPAGTPPGTKK---------VDGISHTSALAPVASSPKECPTEDSGASATASSKG 785
Query: 73 DSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQAPDSATLLEKMK 132
+PS L V + +KR + G P P S +P A+ L +
Sbjct: 786 TLTYLADSPSPLG-----VSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840
Query: 133 LKDSLFDLDGPKVASPLSPTSLTHTSRP-PAALTPVPLSQGDLSHPPRKKDRKN------ 185
L F A+ SPT + P P+A+TP LS ++ PP++ +
Sbjct: 841 LS---FQGSKDSPATTHSPTPPSPKGAPTPSAVTP--LSPKGVTLPPKETPTPSVVNLPF 895
Query: 186 RKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKK------AERGDRLPPPGPPQ 239
K GP A P+ P S KK++ K + +G PP P
Sbjct: 896 PKEGPATPA-------PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP 948
Query: 240 AP------PSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEG- 292
+P PS + + AT AP P TPP PAT P+G
Sbjct: 949 SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008
Query: 293 -VPPADSESKEVGS 305
PPA + GS
Sbjct: 1009 PTPPAVTPPSPKGS 1022
Score = 39.3 bits (90), Expect = 0.006
Identities = 77/332 (23%), Positives = 100/332 (30%), Gaps = 72/332 (21%)
Query: 4 AMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESD--WPASG 61
A+ PSP+ P P T P K T + G PP+ S PA
Sbjct: 1337 AVTPPSPKGTPTL--PATTPSSKGGPTTPSSKE---------GPTPPAATPSHKGGPAMT 1385
Query: 62 SSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQA 121
SP RG + G ++P+ I KKA ++ + G P T
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPA---VIPLSPKKAPATP--VTREGAATPSKGDLT------ 1434
Query: 122 PDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKK 181
P + T + K + GP S +L + P P P S P
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP---- 1490
Query: 182 DRKNRKLGPGAGAGFGVLRRPRPTPGD--------GEKRSRIKK-----SKKRKLKKAER 228
K P A G P P +R I SKK A +
Sbjct: 1491 -----KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPK 1545
Query: 229 GDRLPP----PGPPQAPPSDTDSEEEEEEEEEEEEEEMA----TVVGG------------ 268
+PP P P + P T E +E A T G
Sbjct: 1546 EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAV 1605
Query: 269 ------EAPVPVLPTPPEAPRPPATVHPEGVP 294
EAP P TPP + PAT P+G P
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
Score = 38.5 bits (88), Expect = 0.011
Identities = 73/317 (23%), Positives = 102/317 (32%), Gaps = 65/317 (20%)
Query: 5 MAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPS-KEESDWPASGSS 63
+A PSP+ P T P PP + G PS K PA+
Sbjct: 1186 LATPSPKGAPTT--PAATPPSPK-----------------GGLATPSPKGAPTTPAATPP 1226
Query: 64 SPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQAPD 123
SP G + G + P+ + + + GP P PP+ P
Sbjct: 1227 SPKGGLATPSPKGAPTTPA--------------ATPPSPKGGPATP-PPKGA----PTPP 1267
Query: 124 SATLLEKMKLKDSLFD-----LDGPKVASPLSPTSLTHTSRPPAALTPV----PLSQGDL 174
+AT LK L P V +P SP TS P A TP P +G
Sbjct: 1268 AAT---PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324
Query: 175 SHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKK--SKKRKLKKAERGDRL 232
PP K + P + G L P+ G K+ + + G +
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384
Query: 233 PPPGPPQAP-----------PSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEA 281
PP P + P P+ ++ E AT G+ P + TP
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV-TPVSL 1443
Query: 282 PRPPATVHPEGVPPADS 298
+ PAT P+G P S
Sbjct: 1444 KKAPATSAPKGGPATPS 1460
Score = 37.0 bits (84), Expect = 0.032
Identities = 60/262 (22%), Positives = 83/262 (31%), Gaps = 33/262 (12%)
Query: 50 PSKEESDWPASGSSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKR-RAAQAGPTQ 108
PS +P G ++P ++ A L + KKA+++ + A P+
Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPA-----------LSMTSSSPKKARATPAPKGIPASPSP 936
Query: 109 PGPPRSTFSRLQAPDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVP 168
G P + +P K + P A+P SP T P A TP
Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAPT------PPAATPPSPKGGPATPSPKGAPTPPA 990
Query: 169 LSQGDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAER 228
+ PP K GP + G P TP K S +
Sbjct: 991 AT------PPSPKG------GPATPSPKGAPTPPAVTP-PSPKGSPAATPFPKGASTPPA 1037
Query: 229 GDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATV 288
P G P A P + + AT AP P TPP PAT
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097
Query: 289 HPEG--VPPADSESKEVGSTET 308
P+G +PPA + G T
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLAT 1119
Score = 35.4 bits (80), Expect = 0.092
Identities = 67/307 (21%), Positives = 89/307 (28%), Gaps = 66/307 (21%)
Query: 4 AMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGSS 63
A PSP+ P T P+ P + PP K PA+
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT---------PPHKGAPTTPAATPP 1134
Query: 64 SPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQAPD 123
SP G + G + P+ A + A P G P + + +P
Sbjct: 1135 SPKGGLATPPPKGAPTTPA-----------ATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183
Query: 124 SATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDR 183
K + P L+ S PAA P P +G L+ P K
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP--KGGLATPSPK--- 1238
Query: 184 KNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQAPPS 243
G P TP + G PPP PP+
Sbjct: 1239 -------------GAPTTPAATP-----------------PSPKGGPATPPPKGAPTPPA 1268
Query: 244 DTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEG--VPPADSESK 301
T + +AT AP P + TPP PAT P+G PPA +
Sbjct: 1269 ATPPSLKGG---------LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319
Query: 302 EVGSTET 308
GS T
Sbjct: 1320 PKGSPGT 1326
Score = 33.5 bits (75), Expect = 0.35
Identities = 68/331 (20%), Positives = 108/331 (32%), Gaps = 35/331 (10%)
Query: 4 AMAEPSPEDPPPTLKPETQP--PEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASG 61
A+ PSPE P T P+ P P +++D + V G P + PA
Sbjct: 1618 AVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG-LPAKK 1676
Query: 62 SSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSR--L 119
+ L+ A AP I +K +K+ +A + P P P S+ L
Sbjct: 1677 GPTALKEVLVAP------APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPL 1730
Query: 120 QAPDSATLLEKMKLKDSLFDLDGPKVA-SPLSPTSLTHTSRPPAALTPVPLSQGDLSHPP 178
A LL K DS G + SP P + PP + PL+
Sbjct: 1731 STVAPAPLLPVQK--DSSKTAKGKDASHSPKGPLA------PPESKASTPLTAAAFEKVL 1782
Query: 179 RKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPP 238
K + + P + P PT K++ + G L P P
Sbjct: 1783 PKPESASVSAAPSPPVSLPLAPSPVPT-----------LPPKQQFLPSSPGLVLESPSKP 1831
Query: 239 QAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPV---LPTPPEAPRPPATVHPEGVPP 295
AP + + E +V+ P P +P P + + P T + +G
Sbjct: 1832 LAPADEDELLPLIPPEPISGGVPFQSVLVN-MPTPKSAGIPVPTPSAKQPVTKNNKGSGT 1890
Query: 296 ADSESKEVGSTETSQDGDASSSEGEMRVMDE 326
+ V E A++ + ++ E
Sbjct: 1891 ESDSDESVPELEEQDSTQATTQQAQLAAAAE 1921
Score = 29.3 bits (64), Expect = 6.6
Identities = 43/183 (23%), Positives = 70/183 (38%), Gaps = 17/183 (9%)
Query: 145 VASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKD-RKNRKLGPGAGAGFGVLRRPR 203
V +P P S+ S PPA P +SH + K P +G +
Sbjct: 725 VLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSK 784
Query: 204 PT---PGDGEKRSRIKKSKKRKLKKAERGDRLP--PPGPPQAPPSDTDSE--EEEEEEEE 256
T D + S + K ++G P P G +P S ++ E +
Sbjct: 785 GTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQ 844
Query: 257 EEEEEMATVVGGEAPVPVLPTPPEAPRPPAT--VHPEGV--PPADSESKEVGSTETSQDG 312
++ AT +P P P+P AP P A + P+GV PP ++ + V + ++G
Sbjct: 845 GSKDSPATT---HSPTP--PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG 899
Query: 313 DAS 315
A+
Sbjct: 900 PAT 902
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 46.2 bits (108), Expect = 5e-05
Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 19/159 (11%)
Query: 244 DTDSEEEEEEEEEEE---EEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSES 300
D D + E +EE + + ++E + +A P PP P PPA P PP
Sbjct: 2617 DKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAV 2676
Query: 301 KEVGSTET-----------SQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCRKPF- 348
+ G T ++ SSS+ + + M E+ D+ + C C+ P+
Sbjct: 2677 QHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDT--KLYCICKTPYD 2734
Query: 349 AGRPMIECSLCGTWIHLSCAKI--KKTNVPDFFYCQKCK 385
+ I C C W H C I + + D + C +C+
Sbjct: 2735 ESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQ 2773
Score = 29.3 bits (64), Expect = 6.6
Identities = 36/120 (30%), Positives = 42/120 (35%), Gaps = 60/120 (50%)
Query: 202 PRPTPGD-GEKRSRIKKSKKRKLKKAE------------RG---DRLPPPGPPQAPPS-- 243
P PT G G RSR + S + + A+ RG R PP PP APPS
Sbjct: 29 PPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTS 88
Query: 244 ---------------------------------------DTDSEEEEEEEE---EEEEEE 261
D +SEEEEEEE+ EEEEEE
Sbjct: 89 APGRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEE 148
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 46.2 bits (108), Expect = 5e-05
Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 19/159 (11%)
Query: 244 DTDSEEEEEEEEEEE---EEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSES 300
D D + E +EE + + ++E + +A P PP P PPA P PP
Sbjct: 2634 DKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAV 2693
Query: 301 KEVGSTET-----------SQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCRKPF- 348
+ G T ++ SSS+ + + M E+ D+ + C C+ P+
Sbjct: 2694 QHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDT--KLYCICKTPYD 2751
Query: 349 AGRPMIECSLCGTWIHLSCAKI--KKTNVPDFFYCQKCK 385
+ I C C W H C I + + D + C +C+
Sbjct: 2752 ESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQ 2790
Score = 29.3 bits (64), Expect = 6.6
Identities = 36/120 (30%), Positives = 42/120 (35%), Gaps = 60/120 (50%)
Query: 202 PRPTPGD-GEKRSRIKKSKKRKLKKAE------------RG---DRLPPPGPPQAPPS-- 243
P PT G G RSR + S + + A+ RG R PP PP APPS
Sbjct: 29 PPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPPPPAPPSTS 88
Query: 244 ---------------------------------------DTDSEEEEEEEE---EEEEEE 261
D +SEEEEEEE+ EEEEEE
Sbjct: 89 APGRGGRGGGGGRTGGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEE 148
>gi|192807286 zinc finger and BTB domain containing 4 [Homo sapiens]
Length = 1013
Score = 46.2 bits (108), Expect = 5e-05
Identities = 70/277 (25%), Positives = 105/277 (37%), Gaps = 77/277 (27%)
Query: 4 AMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGSS 63
AM P PPP PE PP V+ +A P S GSS
Sbjct: 450 AMPASPPPGPPPA--PEPGPPPS--------------VITFAHPAP-----SVIVHGGSS 488
Query: 64 SPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGP----PRSTFSRL 119
S G A + G +A ++ T+ + K+R P +P P + S
Sbjct: 489 SGGGGSGTASTGGSQAA-----SVITYTAPPRPPKKREYPPPPPEPAATPTSPATAVSPA 543
Query: 120 QA--PDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHP 177
A P AT E+ K ++ P + +LT+T++P + G P
Sbjct: 544 TAAGPAMATTTEEAKGRN------------PRAGRTLTYTAKPVGGI-------GGGGGP 584
Query: 178 PRKKDRKNRKLGPGAGAGFGVLRRPRP----TPGDGEKRSRIKKSKKRKLKKAE-RGDRL 232
P GAG G L+ P P T GE+ ++ + L+ E G+ +
Sbjct: 585 PT-----------GAGRGPSQLQAPPPLCQITVRIGEEAIVKRRISETDLRPGELSGEEM 633
Query: 233 PPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGE 269
+++ +EEEE+EEEEEE+E + GGE
Sbjct: 634 ----------EESEEDEEEEDEEEEEEDEEESKAGGE 660
>gi|192807284 zinc finger and BTB domain containing 4 [Homo sapiens]
Length = 1013
Score = 46.2 bits (108), Expect = 5e-05
Identities = 70/277 (25%), Positives = 105/277 (37%), Gaps = 77/277 (27%)
Query: 4 AMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGSS 63
AM P PPP PE PP V+ +A P S GSS
Sbjct: 450 AMPASPPPGPPPA--PEPGPPPS--------------VITFAHPAP-----SVIVHGGSS 488
Query: 64 SPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGP----PRSTFSRL 119
S G A + G +A ++ T+ + K+R P +P P + S
Sbjct: 489 SGGGGSGTASTGGSQAA-----SVITYTAPPRPPKKREYPPPPPEPAATPTSPATAVSPA 543
Query: 120 QA--PDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHP 177
A P AT E+ K ++ P + +LT+T++P + G P
Sbjct: 544 TAAGPAMATTTEEAKGRN------------PRAGRTLTYTAKPVGGI-------GGGGGP 584
Query: 178 PRKKDRKNRKLGPGAGAGFGVLRRPRP----TPGDGEKRSRIKKSKKRKLKKAE-RGDRL 232
P GAG G L+ P P T GE+ ++ + L+ E G+ +
Sbjct: 585 PT-----------GAGRGPSQLQAPPPLCQITVRIGEEAIVKRRISETDLRPGELSGEEM 633
Query: 233 PPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGE 269
+++ +EEEE+EEEEEE+E + GGE
Sbjct: 634 ----------EESEEDEEEEDEEEEEEDEEESKAGGE 660
>gi|31581524 cordon-bleu homolog [Homo sapiens]
Length = 1261
Score = 45.8 bits (107), Expect = 7e-05
Identities = 43/171 (25%), Positives = 68/171 (39%), Gaps = 31/171 (18%)
Query: 169 LSQGDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAER 228
LS G +S K + K R+ P G+G P + ++ + L+K +R
Sbjct: 283 LSLGSISGVSVKSEMKKRRAPPPPGSG---------PPVQDKASEKVSLGSQIDLQKKKR 333
Query: 229 GDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATV 288
R P P PPQ PP E++EE + M ++ G +
Sbjct: 334 --RAPAPPPPQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSG---------------SHC 376
Query: 289 HPEGVPPADSESKE---VGSTETSQDGDASSSEGEMRVMDEDIMVESGDDS 336
P+G P SE++E VGS S+ D + G M + + ++S DS
Sbjct: 377 SPDGAPQVLSEAEETVSVGSCFASE--DTTEDSGVMSSPSDIVSLDSQQDS 425
>gi|215599585 integrator complex subunit 12 [Homo sapiens]
Length = 462
Score = 45.4 bits (106), Expect = 9e-05
Identities = 58/247 (23%), Positives = 93/247 (37%), Gaps = 30/247 (12%)
Query: 164 LTPVPLSQGDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKL 223
L P+ L H K + K G+ RP+ D E +I +K +
Sbjct: 9 LDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPSQKDVEP-PKISSTKNISI 67
Query: 224 KKAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPR 283
K+ + P G T+ ++E E+ ++ + G + P PE
Sbjct: 68 KQEPKISSSLPSGNNNGKVLTTEKVKKEAEKRPADKMKSDITEGVDIPKKPRLEKPETQS 127
Query: 284 PPATVHP-EGVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITC 342
P TV + +P AD S E ETS D D + G V+ +MV SG+
Sbjct: 128 SPITVQSSKDLPMADLSSFE----ETSAD-DFAMEMGLACVVCRQMMVASGNQ------- 175
Query: 343 YCRKPFAGRPMIECSLCGTWIHLSCAK----IKKTNVPDF-FYCQKC-KELRPEARRLGG 396
++EC C H C K K+ N P +YC +C ++++ A++
Sbjct: 176 ----------LVECQECHNLYHRDCHKPQVTDKEANDPRLVWYCARCTRQMKRMAQKTQK 225
Query: 397 PPKSGEP 403
PP+ P
Sbjct: 226 PPQKPAP 232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.130 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,031,574
Number of Sequences: 37866
Number of extensions: 1620509
Number of successful extensions: 33706
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 697
Number of HSP's successfully gapped in prelim test: 1105
Number of HSP's that attempted gapping in prelim test: 15970
Number of HSP's gapped (non-prelim): 10549
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.