BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] (1220 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] 2476 0.0 gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] 2476 0.0 gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens] 2438 0.0 gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] 2385 0.0 gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens] 1801 0.0 gi|14149696 SEC31 homolog B [Homo sapiens] 1062 0.0 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 72 4e-12 gi|171543895 ataxin 2 [Homo sapiens] 70 9e-12 gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 70 2e-11 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 66 2e-10 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 65 3e-10 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 65 3e-10 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 65 3e-10 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 9e-10 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 63 2e-09 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 62 3e-09 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 62 3e-09 gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 62 4e-09 gi|58331266 WD repeat domain 59 [Homo sapiens] 61 6e-09 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 60 1e-08 gi|50345997 E1A binding protein p300 [Homo sapiens] 60 1e-08 gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 59 3e-08 gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 59 3e-08 gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 59 3e-08 gi|54860079 nadrin isoform 1 [Homo sapiens] 59 3e-08 gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 59 3e-08 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 4e-08 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 59 4e-08 gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 59 4e-08 gi|163965366 nascent polypeptide-associated complex alpha subuni... 59 4e-08 >gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] Length = 1220 Score = 2476 bits (6417), Expect = 0.0 Identities = 1220/1220 (100%), Positives = 1220/1220 (100%) Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 Query: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV Sbjct: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240 Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP Sbjct: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300 Query: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG Sbjct: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360 Query: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ Sbjct: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420 Query: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN Sbjct: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480 Query: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL Sbjct: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540 Query: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII Sbjct: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600 Query: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA Sbjct: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660 Query: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL Sbjct: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720 Query: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM Sbjct: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780 Query: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP Sbjct: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840 Query: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 900 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA Sbjct: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 900 Query: 901 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 960 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA Sbjct: 901 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 960 Query: 961 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 1020 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI Sbjct: 961 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 1020 Query: 1021 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1080 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS Sbjct: 1021 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1080 Query: 1081 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1140 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK Sbjct: 1081 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1140 Query: 1141 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1200 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE Sbjct: 1141 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1200 Query: 1201 TSAFMPVLKVVLTQANKLGV 1220 TSAFMPVLKVVLTQANKLGV Sbjct: 1201 TSAFMPVLKVVLTQANKLGV 1220 >gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] Length = 1220 Score = 2476 bits (6417), Expect = 0.0 Identities = 1220/1220 (100%), Positives = 1220/1220 (100%) Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 Query: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV Sbjct: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240 Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP Sbjct: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300 Query: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG Sbjct: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360 Query: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ Sbjct: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420 Query: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN Sbjct: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480 Query: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL Sbjct: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540 Query: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII Sbjct: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600 Query: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA Sbjct: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660 Query: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL Sbjct: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720 Query: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM Sbjct: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780 Query: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP Sbjct: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840 Query: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 900 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA Sbjct: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 900 Query: 901 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 960 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA Sbjct: 901 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 960 Query: 961 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 1020 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI Sbjct: 961 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 1020 Query: 1021 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1080 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS Sbjct: 1021 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1080 Query: 1081 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1140 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK Sbjct: 1081 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1140 Query: 1141 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1200 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE Sbjct: 1141 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1200 Query: 1201 TSAFMPVLKVVLTQANKLGV 1220 TSAFMPVLKVVLTQANKLGV Sbjct: 1201 TSAFMPVLKVVLTQANKLGV 1220 >gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens] Length = 1205 Score = 2438 bits (6318), Expect = 0.0 Identities = 1205/1220 (98%), Positives = 1205/1220 (98%), Gaps = 15/1220 (1%) Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 Query: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV Sbjct: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240 Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP Sbjct: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300 Query: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG Sbjct: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360 Query: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ Sbjct: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420 Query: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN Sbjct: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480 Query: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL Sbjct: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540 Query: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII Sbjct: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600 Query: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA Sbjct: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660 Query: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL Sbjct: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720 Query: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM Sbjct: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780 Query: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP Sbjct: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840 Query: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 900 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA Sbjct: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 900 Query: 901 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 960 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA Sbjct: 901 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 960 Query: 961 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 1020 PPSSSAYALPPGT TGPQNGWNDPPALNRVPKKKKMPENFMPPVPI Sbjct: 961 PPSSSAYALPPGT---------------TGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 1005 Query: 1021 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1080 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS Sbjct: 1006 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1065 Query: 1081 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1140 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK Sbjct: 1066 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1125 Query: 1141 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1200 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE Sbjct: 1126 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1185 Query: 1201 TSAFMPVLKVVLTQANKLGV 1220 TSAFMPVLKVVLTQANKLGV Sbjct: 1186 TSAFMPVLKVVLTQANKLGV 1205 >gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] Length = 1181 Score = 2385 bits (6180), Expect = 0.0 Identities = 1181/1220 (96%), Positives = 1181/1220 (96%), Gaps = 39/1220 (3%) Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 Query: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV Sbjct: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240 Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP Sbjct: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300 Query: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG Sbjct: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360 Query: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ Sbjct: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420 Query: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN Sbjct: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480 Query: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540 FEDDSRGKYLELLGYRKEDLGKK Sbjct: 481 FEDDSRGKYLELLGYRKEDLGKK------------------------------------- 503 Query: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600 HIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII Sbjct: 504 --HIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 561 Query: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA Sbjct: 562 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 621 Query: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL Sbjct: 622 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 681 Query: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM Sbjct: 682 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 741 Query: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP Sbjct: 742 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 801 Query: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 900 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA Sbjct: 802 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA 861 Query: 901 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 960 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA Sbjct: 862 PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGA 921 Query: 961 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 1020 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI Sbjct: 922 PPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI 981 Query: 1021 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1080 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS Sbjct: 982 TSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1041 Query: 1081 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1140 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK Sbjct: 1042 KPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTK 1101 Query: 1141 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1200 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE Sbjct: 1102 RKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSE 1161 Query: 1201 TSAFMPVLKVVLTQANKLGV 1220 TSAFMPVLKVVLTQANKLGV Sbjct: 1162 TSAFMPVLKVVLTQANKLGV 1181 >gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens] Length = 1106 Score = 1801 bits (4665), Expect = 0.0 Identities = 957/1222 (78%), Positives = 983/1222 (80%), Gaps = 118/1222 (9%) Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC Sbjct: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK Sbjct: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV Sbjct: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 Query: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV Sbjct: 181 QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPV 240 Query: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP Sbjct: 241 IQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELP 300 Query: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG Sbjct: 301 TNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG 360 Query: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ Sbjct: 361 TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQ 420 Query: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN Sbjct: 421 QQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVN 480 Query: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL Sbjct: 481 FEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL 540 Query: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII Sbjct: 541 GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAII 600 Query: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA Sbjct: 601 LAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYA 660 Query: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL Sbjct: 661 KPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL 720 Query: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM Sbjct: 721 IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIM 780 Query: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP Sbjct: 781 QLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPP 840 Query: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYR-PQQPV 899 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQ Q P A+ R P++ Sbjct: 841 PGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQRPQNGWNDP-----PALNRVPKKKK 895 Query: 900 APPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTS-SPATSFPPPPSSGASFQHGGP 958 P N P P S + G Q Q Q S+P S +SFP P G HG Sbjct: 896 MP--ENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHG-- 951 Query: 959 GAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPV 1018 P G TG MP +F P Sbjct: 952 --------VQQPLGQTG----------------------------------MPPSFSKPN 969 Query: 1019 PITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPS 1078 +P G P Q S P ++ P HL Sbjct: 970 IEGAP-----GAPIGNTFQHVQSLPTKKITKKPIPDEHL--------------------- 1003 Query: 1079 FSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQ 1138 K E + Q S T TK+ + D L+ ++ L ++ LS P Sbjct: 1004 ILKTTFE--------DLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLS----PT 1051 Query: 1139 TKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNF 1198 L + ++ +E + + GL + T N+S Sbjct: 1052 ITSGLHNIARSIE-----------TRNYSEGLTMHTHIVSTSNFS--------------- 1085 Query: 1199 SETSAFMPVLKVVLTQANKLGV 1220 ETSAFMPVLKVVLTQANKLGV Sbjct: 1086 -ETSAFMPVLKVVLTQANKLGV 1106 >gi|14149696 SEC31 homolog B [Homo sapiens] Length = 1179 Score = 1062 bits (2746), Expect = 0.0 Identities = 590/1257 (46%), Positives = 783/1257 (62%), Gaps = 119/1257 (9%) Query: 1 MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSC 60 MKLKE++R A+QAWSPA +P+YLATGTSAQQLD++FSTN +LEIFE+D DPSLD+K Sbjct: 1 MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHR 60 Query: 61 ATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDK 120 S+ R+HKL+WG + + SGV++ GG+NG +ILY+ + I++ KE VIAQ K Sbjct: 61 GVLSALSRFHKLVWGSFGSGLL-ESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQK 119 Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQ-PPEDISCIAWNRQ 179 HTG VRALD+N FQ NL+ASGA++SEI+IWDLNN PMT G+K+Q PPEDI ++WNRQ Sbjct: 120 HTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQ 179 Query: 180 VQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLP 239 QHIL+SA PSG+A VWDLRKNEPIIKVSDHSNRMHCSGLAWHPD+ATQ+VL SEDDRLP Sbjct: 180 AQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLP 239 Query: 240 VIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYEL 299 VIQ+WDLRFASSPL+VLE+H+RGIL+++WS AD ELLL+ KD++ILC N + EV+Y+L Sbjct: 240 VIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKL 299 Query: 300 PTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPF 359 PT + WCFD+QWCPR+P+V SAASF+G IS+YS+MG S + +Q DK+SSSF Sbjct: 300 PTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSK---- 355 Query: 360 GTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAE 419 GQPLPPLQ+P+Q AQ ++ PLKKPPKWIRRP G SF+FGGKLVTF P+H Sbjct: 356 --GQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAH--LV 411 Query: 420 QQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKV 479 Q VFISQV TE EFL RS +LQ+A+ S +NYCQ K + + EK +W FLKV Sbjct: 412 PQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKV 471 Query: 480 NFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQL 539 E DSR K+L+LLGY K++L KK+A L G + + SD +++ ++ Sbjct: 472 TLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQAS- 530 Query: 540 LGEHIKEEKEES-----EFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNR 594 +H +E S E +P + + I ++ DIDGL++QALL G AV+LCL + R Sbjct: 531 --KHTTKEASASSAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEER 588 Query: 595 MADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALA 654 ADAIILA AGG +LL +TQ++Y AK ++KI+ L+ VV KNWK++V +C LKNWREALA Sbjct: 589 FADAIILAQAGGTDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALA 648 Query: 655 AVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHP 714 +LTY+ ++F LCD+LGTR+E EG L ++A LCY+C+G+VE+LV CW K P Sbjct: 649 LLLTYSGTEKFPELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSP 708 Query: 715 LSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNT 774 ++LQDL+EKV++L ++++ + + G +++QYANLLAAQGS+A A++FLP + Sbjct: 709 MALQDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDC 768 Query: 775 NQPNIMQLRDRLCRAQGEPVAGHESPKIPYEK---------QQLPKGRPGPVAGHH---- 821 QP + QLRDRL AQG V G +SP P+ + ++ R G H Sbjct: 769 AQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTP 828 Query: 822 -QMPRVQTQQYYPH----GENPPPPGFIMHGNVN------PNAAGQLPTSPGHMHTQVPP 870 PRV T Q P +P P N++ P A LP SPG P Sbjct: 829 SPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQP 888 Query: 871 Y---------PQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTG 921 P P + P P GS + + P S + P TP + Sbjct: 889 QLLGGQRVQVPNPVGFPGTWPLP----GSPLPMACPGIMRPGSTSLPETPRLFPLLPLRP 944 Query: 922 QSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAAS 981 H T +P SFP P + G PGAP SS LP TTG L Sbjct: 945 LGPGRMVSH-----TPAPPASFPVP------YLPGDPGAPCSS---VLP--TTGIL---- 984 Query: 982 ELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPS 1041 + GPQ+ W + PA ++ K+PE FMPP PIT+P+M+ + Q + PS Sbjct: 985 ----TPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQGIL----PS 1036 Query: 1042 APVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQS 1101 P P+SS S P PG P G +Q Sbjct: 1037 QP-PVSSVSHAP----------------------------------PGVP-GELSLQLQH 1060 Query: 1102 LPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQT 1161 LP +K+ +K +P EH LK++FE L+QRC SATD +TKRKL++A++RLE+LY+KL E T Sbjct: 1061 LPPEKMERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGT 1120 Query: 1162 LSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKL 1218 LSP + +GLH +AR ++ ++ +GL +H + S+FSE S+FMP+LK VL A+KL Sbjct: 1121 LSPHVVAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKL 1177 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 71.6 bits (174), Expect = 4e-12 Identities = 75/284 (26%), Positives = 101/284 (35%), Gaps = 58/284 (20%) Query: 834 HGENPPPPGFIMHGNVNPNAAGQ--------LPTSPGHMHTQVPPYPQPQPYQPA--QPY 883 H PPPG ++ N P G +P P H Q PP QP P QP QP Sbjct: 29 HDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP 88 Query: 884 PFGTGGSAMYRPQQPVAPPTSNAYP-------NTPYISSASSYTGQSQLYAAQHQASSPT 936 P ++ QQP PP ++ P P + SA + + + P Sbjct: 89 PH----PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPG 144 Query: 937 SSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWN 996 S P + PPP+ ++ P PPSS PP G P + +P GP G Sbjct: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVP-----GPGPGPK 199 Query: 997 DPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQ-P 1055 P PK KMP G P +P LS+ P+ P Sbjct: 200 QGPGPGG-PKGGKMP-----------------GGP-------KPGGGPGLSTPGGHPKPP 234 Query: 1056 HLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHV 1099 H GG+P G Q PP + + PG P G + + + Sbjct: 235 HRGGGEPRGGRQH------HPPYHQQHHQGPPPGGPGGRSEEKI 272 Score = 38.9 bits (89), Expect = 0.030 Identities = 50/229 (21%), Positives = 64/229 (27%), Gaps = 55/229 (24%) Query: 793 PVAGHESPKIPY-------EKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPG--- 842 P G PK P ++QQ P +P P P Q PH + PPP Sbjct: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQ---PHQQQQPPPPPQD 105 Query: 843 ----FIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQP 898 + G G P + PP P P P P P Sbjct: 106 SSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP 165 Query: 899 VAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGP 958 P S+ P TP P PPPP + GP Sbjct: 166 PPTPPSSGVPTTP---------------------------PQAGGPPPPPAAVP----GP 194 Query: 959 GAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKK 1007 G P PG G P ++P + G G + P + P + Sbjct: 195 GPGPKQG-----PGPGG--PKGGKMPGGPKPGGGPGLSTPGGHPKPPHR 236 >gi|171543895 ataxin 2 [Homo sapiens] Length = 1313 Score = 70.5 bits (171), Expect = 9e-12 Identities = 76/307 (24%), Positives = 117/307 (38%), Gaps = 44/307 (14%) Query: 789 AQGEPVAG----HESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENP------ 838 A G P+A + + + Y QQ P P+ H +P Q+Q +PH +P Sbjct: 1022 AAGPPIAATPPAYSTQYVAYSPQQFPNQ---PLVQH--VPHYQSQ--HPHVYSPVIQGNA 1074 Query: 839 ---PPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRP 895 PP G V+ +A H P P + P+ + TG A Sbjct: 1075 RMMAPPTHAQPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLA---- 1130 Query: 896 QQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSP----------ATSFPP 945 Q A P + +P+TP+ +++ TGQ Q +QH S P SP A Sbjct: 1131 -QQYAHPNATLHPHTPHPQPSATPTGQQQ---SQHGGSHPAPSPVQHHQHQAAQALHLAS 1186 Query: 946 PPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPAS-QRTGPQNGWNDPPALNRV 1004 P A + G PPS + + + PAA + + + Q + +PP + V Sbjct: 1187 PQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHV 1246 Query: 1005 P----KKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGG 1060 P + +P + P+ P G PQ+ L Q P+P+S+ + FP P Sbjct: 1247 PQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQA-ALAQSALQPIPVSTTAHFPYMTHPSV 1305 Query: 1061 QPFHGVQ 1067 Q H Q Sbjct: 1306 QAHHQQQ 1312 Score = 34.3 bits (77), Expect = 0.74 Identities = 43/208 (20%), Positives = 65/208 (31%), Gaps = 11/208 (5%) Query: 833 PHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAM 892 P + PP + N P A PT P P P P P P T M Sbjct: 557 PSPSSRPPSRYQSGPNSLPPRAAT-PTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRM 615 Query: 893 YRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGAS 952 P P + +P +S+ + + + S + P P + +S Sbjct: 616 SSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSS 675 Query: 953 FQHGGPGAPPSSSAYALP-PGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMP 1011 G P P + P + G P+ L PQ G A+ +P P Sbjct: 676 VVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVL-----ASPQAGIIPTEAV-AMPIPAASP 729 Query: 1012 ENFMPPVPITSPIMNPLGDPQSQMLQQQ 1039 P P ++ + P + + LQ Q Sbjct: 730 ---TPASPASNRAVTPSSEAKDSRLQDQ 754 Score = 32.7 bits (73), Expect = 2.2 Identities = 46/200 (23%), Positives = 65/200 (32%), Gaps = 33/200 (16%) Query: 860 SPGHMHTQVPPYPQPQPYQPAQPYP------FGTGGSA--MYRPQQPVAPPTSNAYPNTP 911 +PG + PP P P P Q P FG+ G+ +RP P P Sbjct: 46 APGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPGSRRLLGLGG--PPRP 103 Query: 912 YISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPP 971 ++ AA +AS P + PP SG S PG P + P Sbjct: 104 FVVLLLPLASPGAPPAAPTRAS-----PLGARASPPRSGVSLARPAPGCPRPACEPVYGP 158 Query: 972 GTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDP 1031 T P + Q+ Q ++ + P P + + P G Sbjct: 159 LTMSLKPQQQQQQQQQQQQQQ---------------QQQQQQQQQPPPAAANVRKPGG-- 201 Query: 1032 QSQMLQQQPSAPVPLSSQSS 1051 S +L +AP P SS S Sbjct: 202 -SGLLASPAAAPSPSSSSVS 220 >gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] Length = 2063 Score = 69.7 bits (169), Expect = 2e-11 Identities = 79/309 (25%), Positives = 107/309 (34%), Gaps = 62/309 (20%) Query: 806 KQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMH 865 +QQ P+G Q+P P G PPP G + N + PG M Sbjct: 295 QQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQ 354 Query: 866 TQVPPYPQ----PQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTG 921 Q+ P P P PYPFG+ QQ S A+ N P +S+ +T Sbjct: 355 QQLQARPSLATVQTPSHPPPPYPFGS--------QQ-----ASQAHTNFPQMSNPGQFTA 401 Query: 922 --QSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPA 979 L + +P P + P SS +SFQ G P + P+ + Sbjct: 402 PQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVN-------------- 447 Query: 980 ASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGD-----PQSQ 1034 Q+ GP R P+ +P+ F PV +SP NP+ P Sbjct: 448 ----QTQQQMGP-----------RPPQNNPLPQGFQQPV--SSPGRNPMVQQGNVPPNFM 490 Query: 1035 MLQQQPSAPVPLS---SQSSFPQPHLPGGQPFHGVQQPLGQTGMPPS--FSKPNIEGAPG 1089 ++QQQP P S P+ PG G P G PS + P GAP Sbjct: 491 VMQQQPPNQGPQSLHPGLGGMPKRLPPGFSA--GQANPNFMQGQVPSTTATTPGNSGAPQ 548 Query: 1090 APIGNTFQH 1098 QH Sbjct: 549 LQANQNVQH 557 Score = 48.1 bits (113), Expect = 5e-05 Identities = 84/378 (22%), Positives = 135/378 (35%), Gaps = 52/378 (13%) Query: 762 SIAAALAFLPDNTNQPNI--------MQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGR 813 S+AA + DN N+ Q R + + V E + E Q G+ Sbjct: 1404 SVAAVGGVVEDNKESLNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQ 1463 Query: 814 PGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQV-PPYP 872 P + +++P V+ + P + N A PG +V PP Sbjct: 1464 P---SDPNKLPSVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVV 1520 Query: 873 QPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNT---PYISSASSYTGQSQLYAAQ 929 + + A P S+ P + P SN ++ P +S SS S Sbjct: 1521 SGEDLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPS----IP 1576 Query: 930 HQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPP-------GTTGTLPAA-- 980 S P SS + S P PP+ F P ++++ ALP T T+P A Sbjct: 1577 PVMSRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPNAGS 1636 Query: 981 ----SELPASQRTGPQNGWNDPPALNR---VPKKKKMPENFMPPVPITS---------PI 1024 SE ++ ++ + + P +N + K + +P P+T+ + Sbjct: 1637 KVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPAAPLTTNSGLMPPSVAV 1696 Query: 1025 MNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNI 1084 + PL PQ+ SAPVP ++ SS P P++ G+P L P P Sbjct: 1697 VGPLHIPQNIKFS---SAPVPPNALSSSPAPNIQTGRPL-----VLSSRATPVQLPSPPC 1748 Query: 1085 EGAPGAPIGNTFQHVQSL 1102 +P P Q V+ L Sbjct: 1749 TSSPVVPSHPPVQQVKEL 1766 Score = 46.6 bits (109), Expect = 1e-04 Identities = 58/232 (25%), Positives = 85/232 (36%), Gaps = 41/232 (17%) Query: 800 PKIPYEK---QQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPG-------------- 842 P P E+ QQ+P VA Q P+ Q Q P + PPPP Sbjct: 974 PSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQM 1033 Query: 843 -FIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQP-AQPYPFGTGGS--AMYRPQQP 898 ++ +P + +LP S +P P P +Q P GS M Q P Sbjct: 1034 MMMLMMQQDPKSV-RLPVSQN-------VHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGP 1085 Query: 899 VAPPTSNAYPNTPY-ISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGG 957 + P S P +++ + +Y Q +P+SSP P + S Sbjct: 1086 ASVPPSPDKQRMPMPVNTPLGSNSRKMVY--QESPQNPSSSPLAEMASLPEASGSEAPSV 1143 Query: 958 PGAPPSSSAYALPPGT----TGTLPAASELPASQRTGPQNGWNDPPALNRVP 1005 PG P + ++ + P TG P S L A+Q PQ P +N +P Sbjct: 1144 PGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQ-----PPVNSLP 1190 Score = 38.5 bits (88), Expect = 0.039 Identities = 74/298 (24%), Positives = 93/298 (31%), Gaps = 65/298 (21%) Query: 810 PKGRPGPVAGHHQMPRVQTQQYYPHG----ENPPPPGFIMHGNVNPNAAGQLPTSPGHMH 865 PK + P + + T P G + PP PG G N+ +LP Sbjct: 914 PKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPG--EQGINLDNSGPKLP----EFS 967 Query: 866 TQVPPYP-QPQPYQPAQPYPFGTGGSAMYRPQ--QPVAPPTSNAYPNTPYISSASSYTGQ 922 + P YP QP +P Q P PQ Q VAPP P P Sbjct: 968 NRPPGYPSQPVEQRPLQQMP----------PQLMQHVAPP-----PQPP----------- 1001 Query: 923 SQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASE 982 Q P PPPPS S Q + P + Sbjct: 1002 --------QQQPQPQLPQQQQPPPPSQPQSQQQ------QQQQQQMMMMLMMQQDPKSVR 1047 Query: 983 LPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQP-S 1041 LP SQ P G LN P ++MP VP+ + P P S Q+ P Sbjct: 1048 LPVSQNVHPPRG-----PLN--PDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMP 1100 Query: 1042 APVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHV 1099 PL S S + + P + PL + P S PG P N HV Sbjct: 1101 VNTPLGSNS---RKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGP-NNMPSHV 1154 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 66.2 bits (160), Expect = 2e-10 Identities = 99/366 (27%), Positives = 118/366 (32%), Gaps = 52/366 (14%) Query: 788 RAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG 847 + QG P G P+ P P+G P P G+ P+ P G PPP G Sbjct: 56 KPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNK--PQGPPPPGKPQG--PPPQGDKSRS 110 Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAY 907 +P Q P G Q PP P P +P P P G +PQ P P Sbjct: 111 PRSPPGKPQGPPPQGGNQPQGPP---PPPGKPQGPPPQGGN-----KPQGPPPPGKPQGP 162 Query: 908 PNTPYISSASSYT--GQSQLYAAQ--HQASSPTSSPATSFPPPPSSGASFQH----GGPG 959 P S SS + G+ Q Q +Q P P PPP G Q G P Sbjct: 163 PPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 222 Query: 960 APP------SSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPEN 1013 PP S SA + P G P P P PP P+ P Sbjct: 223 GPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 282 Query: 1014 FMPPVP--------ITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQ----------P 1055 P P SP P G P Q Q P P Q PQ P Sbjct: 283 PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 342 Query: 1056 HLPGGQPFHG------VQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITK 1109 P G P G + P G+ PP N +G P P G Q Q+ P + Sbjct: 343 GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP-PPAGGNPQQPQAPPAGQPQG 401 Query: 1110 KPIPDE 1115 P P + Sbjct: 402 PPRPPQ 407 Score = 57.8 bits (138), Expect = 6e-08 Identities = 73/265 (27%), Positives = 88/265 (33%), Gaps = 31/265 (11%) Query: 838 PPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQ 897 PP G G +P Q P G Q PP P +P P P G P + Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNKPQGPPPPGK 97 Query: 898 PVAPPTSNAYPNTPYISSASSYTGQSQLYAAQ--HQASSPTSSPATSFPPPPSSGASFQH 955 P PP P S S G+ Q Q +Q P P PPP G Q Sbjct: 98 PQGPP-----PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ- 151 Query: 956 GGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMP---- 1011 G PP PP ++ P + P G N P P K + P Sbjct: 152 ---GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 208 Query: 1012 --ENFMPPVPITSPIMNPLGDPQSQMLQQ---QPSAPVPLSS---QSSFPQPHLPGGQPF 1063 + PP P P GD +SQ + +P P P Q P P P G P Sbjct: 209 GNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 268 Query: 1064 HGVQQPLGQTGMPPSFSKPNIEGAP 1088 G +P G PP KP +G P Sbjct: 269 QGGNKPQG----PPPPGKP--QGPP 287 Score = 46.2 bits (108), Expect = 2e-04 Identities = 49/184 (26%), Positives = 62/184 (33%), Gaps = 9/184 (4%) Query: 788 RAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG 847 + QG P G P+ P P+G P P G+ P+ P G PP G Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNK--PQGPPPPGKPQGP-PPQGGSKSRS 296 Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAY 907 + +P Q P G Q PP P +P P P G P +P PP Sbjct: 297 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNKPQGPPPPGKPQGPPPQGGS 354 Query: 908 PNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAY 967 + S G Q Q P PA P P + + Q GP PP Sbjct: 355 KSRSARSPPGKPQGPPQQEGNNPQGPPP---PAGGNPQQPQAPPAGQPQGPPRPPQGGRP 411 Query: 968 ALPP 971 + PP Sbjct: 412 SRPP 415 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 65.5 bits (158), Expect = 3e-10 Identities = 100/354 (28%), Positives = 141/354 (39%), Gaps = 58/354 (16%) Query: 790 QGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQY-YPHGENPPPPGFIMHGN 848 QG P A ++P P Q P P P Q P + Q+ PH PPP H Sbjct: 222 QGSPTAS-QAPNQP----QAPTA-PVPHTHIQQAPALHPQRPPSPH----PPPHPSPHPP 271 Query: 849 VNP--NAAGQLPTSPGH----MHTQVPPYPQ-----PQPYQPAQPYPFGTGGSAMYRPQQ 897 + P +AGQ P++P H +H Q PP P P P P PFG A + Q Sbjct: 272 LQPLTGSAGQ-PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS-QGQA 329 Query: 898 PVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGG 957 P+ + AYP+T AS QSQ + Q P PPP++ Sbjct: 330 PLGTSPAAAYPHTSLQLPASQSALQSQ-QPPREQPLPPAPLAMPHIKPPPTTPIP----- 383 Query: 958 PGAPPSSSAYALPPGTTGTLPAA--SELPASQRTGPQNGWND--PPALNRVPKKKKMPEN 1013 P+ A+ PP +G P + + LP P + + PP+ + P + MP++ Sbjct: 384 --QLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHP-PPLQLMPQS 440 Query: 1014 FMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQ------PHLPGGQPFHGVQ 1067 P+ S P G QSQ L P++ P PQ P +PGG P + Sbjct: 441 ----QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP--PIT 494 Query: 1068 QP-LGQTGMPP----SFSKPNIEGAPGAPIGNTFQHVQS--LPTKKITKKPIPD 1114 P T PP + ++P GA A G + S LPT +I ++ + D Sbjct: 495 PPTCPSTSTPPAGPGTSAQPPCSGA--AASGGSIAGGSSCPLPTVQIKEEALDD 546 Score = 55.5 bits (132), Expect = 3e-07 Identities = 74/297 (24%), Positives = 102/297 (34%), Gaps = 43/297 (14%) Query: 840 PPGFIMHGNVNPNAAGQLPT-SPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQP 898 P G + P QLPT P T VPP P T A +PQ P Sbjct: 190 PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP------------TASQAPNQPQAP 237 Query: 899 VAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHG-G 957 AP P + + + + H P + A P PS HG G Sbjct: 238 TAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ-PSAPSHAQPPLHGQG 296 Query: 958 PGAPPSSSAYAL-----PPGTTGTLPAASELPASQRTGPQNGWND-----PPALNRVPKK 1007 P P S A L PP G P AS+ A T P + P + + + + Sbjct: 297 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356 Query: 1008 KKMPENFMPPVPITSPIMNP--------LGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPG 1059 + E +PP P+ P + P L PQ+ S P P S ++ P P P Sbjct: 357 QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP--PA 414 Query: 1060 GQPFHGVQQPLGQTGMPPSF-----SKPNIEGAPGAPIGNTFQHVQSLPTKKITKKP 1111 +P + + PP S+P + +P P G T Q+LP + P Sbjct: 415 LKPLSSLSTHHPPSAHPPPLQLMPQSQP-LPSSPAQPPGLT--QSQNLPPPPASHPP 468 Score = 52.0 bits (123), Expect = 3e-06 Identities = 64/246 (26%), Positives = 84/246 (34%), Gaps = 43/246 (17%) Query: 903 TSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPP 962 TS + P+ S S + Q Q+ QA P T P PSS P P Sbjct: 157 TSPSIPSPQDNESDSDSSAQQQML----QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 212 Query: 963 SSSAYALPPGTTGTLPAASELP-ASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPIT 1021 + SA A+PP + T A P A P PAL+ ++ P PP P Sbjct: 213 TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH----PQRPPSPHPPPHPSP 268 Query: 1022 SPIMNPL----GDP---------------------QSQMLQQQPSAPVPLSSQSSFPQPH 1056 P + PL G P Q+ L Q P P P Q Sbjct: 269 HPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 328 Query: 1057 LPGG------QPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKK 1110 P G P +Q P Q+ + S P + P AP+ H++ PT I + Sbjct: 329 APLGTSPAAAYPHTSLQLPASQSAL-QSQQPPREQPLPPAPL--AMPHIKPPPTTPIPQL 385 Query: 1111 PIPDEH 1116 P P H Sbjct: 386 PAPQAH 391 Score = 49.7 bits (117), Expect = 2e-05 Identities = 64/244 (26%), Positives = 95/244 (38%), Gaps = 42/244 (17%) Query: 789 AQGEPVAGHESPKIPYEKQQLPK-GRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG 847 + +P + P P+ Q P PGP P+ +Q P G +P Sbjct: 286 SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA-SQGQAPLGTSPAA------- 337 Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQP-AQPYPFGTGGSAMYRPQQPVAP-PTSN 905 P+ + QLP S + +Q PP QP P P A P+ P P+ P Sbjct: 338 -AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH-------IKPPPTTPIPQLPAPQ 389 Query: 906 AYPNTPYISSASSYTGQSQL---YAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPP 962 A+ + P++S S ++ + L A + +S T P ++ PPP P + P Sbjct: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL-------MPQSQP 442 Query: 963 SSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRV-PKKKKMPENFMP--PVP 1019 S+ A PPG T SQ P + P L++V P+ F+P P P Sbjct: 443 LPSSPAQPPGLT----------QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP 492 Query: 1020 ITSP 1023 IT P Sbjct: 493 ITPP 496 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 65.5 bits (158), Expect = 3e-10 Identities = 100/354 (28%), Positives = 141/354 (39%), Gaps = 58/354 (16%) Query: 790 QGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQY-YPHGENPPPPGFIMHGN 848 QG P A ++P P Q P P P Q P + Q+ PH PPP H Sbjct: 776 QGSPTAS-QAPNQP----QAPTA-PVPHTHIQQAPALHPQRPPSPH----PPPHPSPHPP 825 Query: 849 VNP--NAAGQLPTSPGH----MHTQVPPYPQ-----PQPYQPAQPYPFGTGGSAMYRPQQ 897 + P +AGQ P++P H +H Q PP P P P P PFG A + Q Sbjct: 826 LQPLTGSAGQ-PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS-QGQA 883 Query: 898 PVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGG 957 P+ + AYP+T AS QSQ + Q P PPP++ Sbjct: 884 PLGTSPAAAYPHTSLQLPASQSALQSQ-QPPREQPLPPAPLAMPHIKPPPTTPIP----- 937 Query: 958 PGAPPSSSAYALPPGTTGTLPAA--SELPASQRTGPQNGWND--PPALNRVPKKKKMPEN 1013 P+ A+ PP +G P + + LP P + + PP+ + P + MP++ Sbjct: 938 --QLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHP-PPLQLMPQS 994 Query: 1014 FMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQ------PHLPGGQPFHGVQ 1067 P+ S P G QSQ L P++ P PQ P +PGG P + Sbjct: 995 ----QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP--PIT 1048 Query: 1068 QP-LGQTGMPP----SFSKPNIEGAPGAPIGNTFQHVQS--LPTKKITKKPIPD 1114 P T PP + ++P GA A G + S LPT +I ++ + D Sbjct: 1049 PPTCPSTSTPPAGPGTSAQPPCSGA--AASGGSIAGGSSCPLPTVQIKEEALDD 1100 Score = 55.5 bits (132), Expect = 3e-07 Identities = 74/297 (24%), Positives = 102/297 (34%), Gaps = 43/297 (14%) Query: 840 PPGFIMHGNVNPNAAGQLPT-SPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQP 898 P G + P QLPT P T VPP P T A +PQ P Sbjct: 744 PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP------------TASQAPNQPQAP 791 Query: 899 VAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHG-G 957 AP P + + + + H P + A P PS HG G Sbjct: 792 TAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ-PSAPSHAQPPLHGQG 850 Query: 958 PGAPPSSSAYAL-----PPGTTGTLPAASELPASQRTGPQNGWND-----PPALNRVPKK 1007 P P S A L PP G P AS+ A T P + P + + + + Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 910 Query: 1008 KKMPENFMPPVPITSPIMNP--------LGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPG 1059 + E +PP P+ P + P L PQ+ S P P S ++ P P P Sbjct: 911 QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP--PA 968 Query: 1060 GQPFHGVQQPLGQTGMPPSF-----SKPNIEGAPGAPIGNTFQHVQSLPTKKITKKP 1111 +P + + PP S+P + +P P G T Q+LP + P Sbjct: 969 LKPLSSLSTHHPPSAHPPPLQLMPQSQP-LPSSPAQPPGLT--QSQNLPPPPASHPP 1022 Score = 52.0 bits (123), Expect = 3e-06 Identities = 64/246 (26%), Positives = 84/246 (34%), Gaps = 43/246 (17%) Query: 903 TSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPP 962 TS + P+ S S + Q Q+ QA P T P PSS P P Sbjct: 711 TSPSIPSPQDNESDSDSSAQQQML----QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 766 Query: 963 SSSAYALPPGTTGTLPAASELP-ASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPIT 1021 + SA A+PP + T A P A P PAL+ ++ P PP P Sbjct: 767 TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH----PQRPPSPHPPPHPSP 822 Query: 1022 SPIMNPL----GDP---------------------QSQMLQQQPSAPVPLSSQSSFPQPH 1056 P + PL G P Q+ L Q P P P Q Sbjct: 823 HPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 882 Query: 1057 LPGG------QPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKK 1110 P G P +Q P Q+ + S P + P AP+ H++ PT I + Sbjct: 883 APLGTSPAAAYPHTSLQLPASQSAL-QSQQPPREQPLPPAPL--AMPHIKPPPTTPIPQL 939 Query: 1111 PIPDEH 1116 P P H Sbjct: 940 PAPQAH 945 Score = 49.7 bits (117), Expect = 2e-05 Identities = 64/244 (26%), Positives = 95/244 (38%), Gaps = 42/244 (17%) Query: 789 AQGEPVAGHESPKIPYEKQQLPK-GRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG 847 + +P + P P+ Q P PGP P+ +Q P G +P Sbjct: 840 SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA-SQGQAPLGTSPAA------- 891 Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQP-AQPYPFGTGGSAMYRPQQPVAP-PTSN 905 P+ + QLP S + +Q PP QP P P A P+ P P+ P Sbjct: 892 -AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH-------IKPPPTTPIPQLPAPQ 943 Query: 906 AYPNTPYISSASSYTGQSQL---YAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPP 962 A+ + P++S S ++ + L A + +S T P ++ PPP P + P Sbjct: 944 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL-------MPQSQP 996 Query: 963 SSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRV-PKKKKMPENFMP--PVP 1019 S+ A PPG T SQ P + P L++V P+ F+P P P Sbjct: 997 LPSSPAQPPGLT----------QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP 1046 Query: 1020 ITSP 1023 IT P Sbjct: 1047 ITPP 1050 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 65.5 bits (158), Expect = 3e-10 Identities = 100/354 (28%), Positives = 141/354 (39%), Gaps = 58/354 (16%) Query: 790 QGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQY-YPHGENPPPPGFIMHGN 848 QG P A ++P P Q P P P Q P + Q+ PH PPP H Sbjct: 776 QGSPTAS-QAPNQP----QAPTA-PVPHTHIQQAPALHPQRPPSPH----PPPHPSPHPP 825 Query: 849 VNP--NAAGQLPTSPGH----MHTQVPPYPQ-----PQPYQPAQPYPFGTGGSAMYRPQQ 897 + P +AGQ P++P H +H Q PP P P P P PFG A + Q Sbjct: 826 LQPLTGSAGQ-PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQAS-QGQA 883 Query: 898 PVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGG 957 P+ + AYP+T AS QSQ + Q P PPP++ Sbjct: 884 PLGTSPAAAYPHTSLQLPASQSALQSQ-QPPREQPLPPAPLAMPHIKPPPTTPIP----- 937 Query: 958 PGAPPSSSAYALPPGTTGTLPAA--SELPASQRTGPQNGWND--PPALNRVPKKKKMPEN 1013 P+ A+ PP +G P + + LP P + + PP+ + P + MP++ Sbjct: 938 --QLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHP-PPLQLMPQS 994 Query: 1014 FMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQ------PHLPGGQPFHGVQ 1067 P+ S P G QSQ L P++ P PQ P +PGG P + Sbjct: 995 ----QPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP--PIT 1048 Query: 1068 QP-LGQTGMPP----SFSKPNIEGAPGAPIGNTFQHVQS--LPTKKITKKPIPD 1114 P T PP + ++P GA A G + S LPT +I ++ + D Sbjct: 1049 PPTCPSTSTPPAGPGTSAQPPCSGA--AASGGSIAGGSSCPLPTVQIKEEALDD 1100 Score = 55.5 bits (132), Expect = 3e-07 Identities = 74/297 (24%), Positives = 102/297 (34%), Gaps = 43/297 (14%) Query: 840 PPGFIMHGNVNPNAAGQLPT-SPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQP 898 P G + P QLPT P T VPP P T A +PQ P Sbjct: 744 PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSP------------TASQAPNQPQAP 791 Query: 899 VAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHG-G 957 AP P + + + + H P + A P PS HG G Sbjct: 792 TAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQ-PSAPSHAQPPLHGQG 850 Query: 958 PGAPPSSSAYAL-----PPGTTGTLPAASELPASQRTGPQNGWND-----PPALNRVPKK 1007 P P S A L PP G P AS+ A T P + P + + + + Sbjct: 851 PPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 910 Query: 1008 KKMPENFMPPVPITSPIMNP--------LGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPG 1059 + E +PP P+ P + P L PQ+ S P P S ++ P P P Sbjct: 911 QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP--PA 968 Query: 1060 GQPFHGVQQPLGQTGMPPSF-----SKPNIEGAPGAPIGNTFQHVQSLPTKKITKKP 1111 +P + + PP S+P + +P P G T Q+LP + P Sbjct: 969 LKPLSSLSTHHPPSAHPPPLQLMPQSQP-LPSSPAQPPGLT--QSQNLPPPPASHPP 1022 Score = 52.0 bits (123), Expect = 3e-06 Identities = 64/246 (26%), Positives = 84/246 (34%), Gaps = 43/246 (17%) Query: 903 TSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPP 962 TS + P+ S S + Q Q+ QA P T P PSS P P Sbjct: 711 TSPSIPSPQDNESDSDSSAQQQML----QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 766 Query: 963 SSSAYALPPGTTGTLPAASELP-ASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPIT 1021 + SA A+PP + T A P A P PAL+ ++ P PP P Sbjct: 767 TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH----PQRPPSPHPPPHPSP 822 Query: 1022 SPIMNPL----GDP---------------------QSQMLQQQPSAPVPLSSQSSFPQPH 1056 P + PL G P Q+ L Q P P P Q Sbjct: 823 HPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQ 882 Query: 1057 LPGG------QPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKK 1110 P G P +Q P Q+ + S P + P AP+ H++ PT I + Sbjct: 883 APLGTSPAAAYPHTSLQLPASQSAL-QSQQPPREQPLPPAPL--AMPHIKPPPTTPIPQL 939 Query: 1111 PIPDEH 1116 P P H Sbjct: 940 PAPQAH 945 Score = 49.7 bits (117), Expect = 2e-05 Identities = 64/244 (26%), Positives = 95/244 (38%), Gaps = 42/244 (17%) Query: 789 AQGEPVAGHESPKIPYEKQQLPK-GRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG 847 + +P + P P+ Q P PGP P+ +Q P G +P Sbjct: 840 SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA-SQGQAPLGTSPAA------- 891 Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQP-AQPYPFGTGGSAMYRPQQPVAP-PTSN 905 P+ + QLP S + +Q PP QP P P A P+ P P+ P Sbjct: 892 -AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH-------IKPPPTTPIPQLPAPQ 943 Query: 906 AYPNTPYISSASSYTGQSQL---YAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPP 962 A+ + P++S S ++ + L A + +S T P ++ PPP P + P Sbjct: 944 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQL-------MPQSQP 996 Query: 963 SSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRV-PKKKKMPENFMP--PVP 1019 S+ A PPG T SQ P + P L++V P+ F+P P P Sbjct: 997 LPSSPAQPPGLT----------QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP 1046 Query: 1020 ITSP 1023 IT P Sbjct: 1047 ITPP 1050 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 63.9 bits (154), Expect = 9e-10 Identities = 80/293 (27%), Positives = 106/293 (36%), Gaps = 52/293 (17%) Query: 810 PKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAG--QLPTSPGHMHTQ 867 P RP P + PR H P P P+A G Q P S + Sbjct: 185 PSARPRPPT---EGPRKSVSSASEHSTTEPSPA----ARRRPSAGGGLQRPASRSLSSSA 237 Query: 868 VP--------PYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSY 919 P P + P PA P G RP Q V PP +A P +SS Sbjct: 238 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ-VTPPRKDAAPALGPLSS---- 292 Query: 920 TGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQ--HGGPGAPPSSSAYALPPGTTGTL 977 SP ++P+ S PP PS+ S Q P PPS + +L G+ Sbjct: 293 --------------SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL--GSPTLQ 336 Query: 978 PAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQ 1037 S LP+ P + PP + P +P PP P SP ++PL P Sbjct: 337 ATHSFLPSP----PLSPLATPPP--QAPPALALPPLQAPPSPPASPPLSPLATPS----P 386 Query: 1038 QQPSAPVPLSSQSSF-PQPHLPGGQPFH-GVQQPLGQTGMPPSFSKPNIEGAP 1088 Q P+A Q+ F P P P PF P+ + PPS + P++ P Sbjct: 387 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 439 Score = 55.5 bits (132), Expect = 3e-07 Identities = 80/318 (25%), Positives = 110/318 (34%), Gaps = 77/318 (24%) Query: 851 PNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQP-------------------YPFGTGGSA 891 P+A G P +P H P P+P+ Q +P P T + Sbjct: 248 PSARGT-PRAPAH-----PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301 Query: 892 MYRPQQPVAPPTSNAYPNTPYI--SSASSYTGQSQLYAAQHQASSPTSSPATSFPP---- 945 P P APP+ P+ P S A++ G L A SP SP + PP Sbjct: 302 A--PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359 Query: 946 ---------PPSSGAS-----FQHGGPGAPPSSSAYALP----PGTTGTLPAASELPASQ 987 PPS AS P AP + + + L P + + A PAS Sbjct: 360 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419 Query: 988 RTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMN-----------PLGDPQSQML 1036 P PP+ + P P +PP P SP M+ PL P Q+ Sbjct: 420 PVSPSA---TPPS--QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 474 Query: 1037 QQQPSAPVPLSSQ--SSFPQP--HLPGGQPFH-GVQQPLGQTGMPPS-----FSKPNIEG 1086 + P AP L++ + P P PG PF P+ PP + P ++ Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534 Query: 1087 APGAPIGNTFQHVQSLPT 1104 P P T Q + PT Sbjct: 535 PPSPPASPTLQAPRRPPT 552 Score = 45.1 bits (105), Expect = 4e-04 Identities = 57/222 (25%), Positives = 74/222 (33%), Gaps = 34/222 (15%) Query: 800 PKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGN--VNPNAA--G 855 P P P P P A + + + P P F + V+P+A Sbjct: 370 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429 Query: 856 QLPTSPGHMHTQVPPYPQPQPYQ-------PAQPYPFGTGGSAMYRPQQPVAPPTSNAYP 908 Q P S QVPP P P P P P + +P P APP P Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP-PQAPPALATPP 488 Query: 909 NTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPP---------PPSSGASFQHGGPG 959 S +S+ GQ+ + SP ++P PP PPS AS P Sbjct: 489 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548 Query: 960 APPSSS----------AYALPPGTTGTLPAASELPASQRTGP 991 PP+ AL PG P S P+S +GP Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGP 587 Score = 33.1 bits (74), Expect = 1.7 Identities = 60/233 (25%), Positives = 70/233 (30%), Gaps = 46/233 (19%) Query: 800 PKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPT 859 P + Q+P P P A P P PP + P A L T Sbjct: 433 PSLAAPPLQVP---PSPPASPPMSPSATPPPQAPPPLAAPP---LQLAKPPPQAPPALAT 486 Query: 860 SPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYP--NTPYISSAS 917 P + P P P Q PF S P P+A P A P P + Sbjct: 487 PP------LQALPSPPASFPGQA-PFSPSASL---PMSPLATPPPQAPPVLAAPLLQVPP 536 Query: 918 SYTGQSQLYAAQHQASSPTSSPATSF-------------PPPPSSGASFQHGGPG-APPS 963 S L A + PT P TS PPPPS S GP A S Sbjct: 537 SPPASPTLQAPRRP---PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 593 Query: 964 SSAYALPP-----------GTTGTLPAASELPASQRTGPQNGWNDPPALNRVP 1005 SSA + P G + P +EL A G P A P Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 646 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 62.8 bits (151), Expect = 2e-09 Identities = 87/308 (28%), Positives = 110/308 (35%), Gaps = 52/308 (16%) Query: 810 PKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAG--QLPTSPGHMHTQ 867 P RP P + PR H P P P+A G Q P S + Sbjct: 194 PSARPRPPT---EGPRKSVSSASEHSTTEPSPA----ARRRPSAGGGLQRPASRSLSSSA 246 Query: 868 VP--------PYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYP------NTPYI 913 P P + P PA P G RP Q V PP +A P ++P Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ-VTPPRKDAAPALGPLSSSPLA 305 Query: 914 SSASSYTGQSQ----LYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYAL 969 + + S QSQ L A H +SS T AT P P S P APPS Sbjct: 306 TPSPSAALQSQAPPTLPATPH-SSSLTCQLATPLPLAPPS--------PSAPPSLQTLPS 356 Query: 970 PPGTTGTLPAAS-ELPASQRT------GPQNGWNDPPALNRVPKKKKMPENFMPPVPITS 1022 PP T + S P Q T P + PP + P +P PP P S Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP--QAPPALALPPLQAPPSPPAS 414 Query: 1023 PIMNPLGDPQSQMLQQQPSAPVPLSSQSSF-PQPHLPGGQPFH-GVQQPLGQTGMPPSFS 1080 P ++PL P Q P+A Q+ F P P P PF P+ + PPS + Sbjct: 415 PPLSPLATPS----PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 470 Query: 1081 KPNIEGAP 1088 P++ P Sbjct: 471 PPSLAAPP 478 Score = 57.8 bits (138), Expect = 6e-08 Identities = 76/298 (25%), Positives = 104/298 (34%), Gaps = 64/298 (21%) Query: 858 PTSPGHMHTQVPPYPQPQPY------QPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTP 911 P+ + +Q PP P+ Q A P P P P APP+ P+ P Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA--------PPSPSAPPSLQTLPSPP 358 Query: 912 YI--SSASSYTGQSQLYAAQHQASSPTSSPATSFPP-------------PPSSGAS---- 952 S A++ G L A SP SP + PP PPS AS Sbjct: 359 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 418 Query: 953 -FQHGGPGAPPSSSAYALP----PGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKK 1007 P AP + + + L P + + A PAS P PP+ + P Sbjct: 419 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA---TPPS--QAPPS 473 Query: 1008 KKMPENFMPPVPITSPIMN-----------PLGDPQSQMLQQQPSAPVPLSSQ--SSFPQ 1054 P +PP P SP M+ PL P Q+ + P AP L++ + P Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPS 533 Query: 1055 P--HLPGGQPFH-GVQQPLGQTGMPPS-----FSKPNIEGAPGAPIGNTFQHVQSLPT 1104 P PG PF P+ PP + P ++ P P T Q + PT Sbjct: 534 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 591 Score = 45.1 bits (105), Expect = 4e-04 Identities = 57/222 (25%), Positives = 74/222 (33%), Gaps = 34/222 (15%) Query: 800 PKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGN--VNPNAA--G 855 P P P P P A + + + P P F + V+P+A Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 468 Query: 856 QLPTSPGHMHTQVPPYPQPQPYQ-------PAQPYPFGTGGSAMYRPQQPVAPPTSNAYP 908 Q P S QVPP P P P P P + +P P APP P Sbjct: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP-PQAPPALATPP 527 Query: 909 NTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPP---------PPSSGASFQHGGPG 959 S +S+ GQ+ + SP ++P PP PPS AS P Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 587 Query: 960 APPSSS----------AYALPPGTTGTLPAASELPASQRTGP 991 PP+ AL PG P S P+S +GP Sbjct: 588 RPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGP 626 Score = 33.1 bits (74), Expect = 1.7 Identities = 60/233 (25%), Positives = 70/233 (30%), Gaps = 46/233 (19%) Query: 800 PKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPT 859 P + Q+P P P A P P PP + P A L T Sbjct: 472 PSLAAPPLQVP---PSPPASPPMSPSATPPPQAPPPLAAPP---LQLAKPPPQAPPALAT 525 Query: 860 SPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYP--NTPYISSAS 917 P + P P P Q PF S P P+A P A P P + Sbjct: 526 PP------LQALPSPPASFPGQA-PFSPSASL---PMSPLATPPPQAPPVLAAPLLQVPP 575 Query: 918 SYTGQSQLYAAQHQASSPTSSPATSF-------------PPPPSSGASFQHGGPG-APPS 963 S L A + PT P TS PPPPS S GP A S Sbjct: 576 SPPASPTLQAPRRP---PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 632 Query: 964 SSAYALPP-----------GTTGTLPAASELPASQRTGPQNGWNDPPALNRVP 1005 SSA + P G + P +EL A G P A P Sbjct: 633 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 685 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 62.0 bits (149), Expect = 3e-09 Identities = 83/336 (24%), Positives = 108/336 (32%), Gaps = 62/336 (18%) Query: 798 ESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQL 857 E+ P K++ GR HH ++Q Q P + PPPP Q Sbjct: 718 ETEMAPKSKKKGHPGREQKKHHHHHHQQMQ-QAPAPVPQQPPPP------------PQQP 764 Query: 858 PTSPGHMHTQVPPYPQPQPYQPAQ--------PYPFGTGGSAMYRPQ------------- 896 P P Q PP P P P P Q P PF + PQ Sbjct: 765 PPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFT 824 Query: 897 -------QPVAPPTSNAYP--NTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPP 947 QP PP P +TP + + L+ A Q S S+ A + PP P Sbjct: 825 QPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKP 884 Query: 948 SSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKK 1007 + P P+ + L P P L + P + +K Sbjct: 885 ARP-------PAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQK 937 Query: 1008 KKMPENFMPPVPITSPIMNPLGDPQ----SQMLQQQPSAPVPLSSQSSFPQPHLPGGQPF 1063 + P +P V + S PL P Q LQQQP P P Q Q H P +P Sbjct: 938 VQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPV 997 Query: 1064 H--------GVQQPLGQTGMPPSFSKPNIEGAPGAP 1091 H +QQP G P P + P P Sbjct: 998 HLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP 1033 Score = 47.4 bits (111), Expect = 8e-05 Identities = 76/301 (25%), Positives = 102/301 (33%), Gaps = 57/301 (18%) Query: 788 RAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG 847 + Q +P P P +QQL + P P Q P Q Q P + P F H Sbjct: 949 KVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHI 1008 Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPY---------------PFGTG---- 888 P GQ P P PP QP P QPA+P P+ TG Sbjct: 1009 QQPPPPQGQQPPHP-------PPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLRE 1061 Query: 889 ---GSAMYRPQQP-------VAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSP--T 936 ++ PQ +PP N P + +AS Q + + + SP Sbjct: 1062 APSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIR 1121 Query: 937 SSP-ATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGW 995 S P + S P P P P S A P P P R QN Sbjct: 1122 SEPFSPSLRPEP----------PKHPESIKAPVHLPQRPEMKPVDVGRPVI-RPPEQNA- 1169 Query: 996 NDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAP--VPLSSQSSFP 1053 PP K+K+ P+ P P + +G + ++Q+ P+ P SS SF Sbjct: 1170 -PPPGAPDKDKQKQEPKT--PVAPKKDLKIKNMGS-WASLVQKHPTTPSSTAKSSSDSFE 1225 Query: 1054 Q 1054 Q Sbjct: 1226 Q 1226 Score = 31.2 bits (69), Expect = 6.3 Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 31/148 (20%) Query: 824 PRVQTQQYYPHGENPPPPGFIMHG--NVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQ 881 P+ QT Q NPPP H V P+ Q P T VPP QP Q Sbjct: 206 PQTQTPQ-----PNPPPVQATPHPFPAVTPDLIVQTPVM-----TVVPP----QPLQTPP 251 Query: 882 PYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTS---- 937 P P +PQ P AP + P I++ + + ++PT+ Sbjct: 252 PVP--------PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI 303 Query: 938 SPATSFPPPPSS---GASFQHGGPGAPP 962 S PP P + G + P PP Sbjct: 304 HEPPSLPPEPKTTKLGQRRESSRPVKPP 331 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 62.0 bits (149), Expect = 3e-09 Identities = 88/314 (28%), Positives = 106/314 (33%), Gaps = 33/314 (10%) Query: 790 QGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNV 849 QG G P+ P P+G P P G+ P+ P G PPP G Sbjct: 37 QGPSPQGGNKPQGPPPPPGKPQGPP-PQGGNK--PQGPPPPGKPQG--PPPQGDKSRSPR 91 Query: 850 NPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPN 909 +P Q P G Q PP P +P P P G P +P PP P Sbjct: 92 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNRPQGPPPPGKPQGPP-----PQ 144 Query: 910 TPYISSASSYTGQSQLYAAQ--HQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAY 967 S S G+ Q Q +Q P P PPP G Q G PP Sbjct: 145 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQ----GPPPPGKPQ 200 Query: 968 ALPPGTTGTLPAASELPASQRTG-PQNGWNDPPALNRVPKKKKMP-----ENFMPPVPIT 1021 PP G +S+ P + G P G N P P K + P P P Sbjct: 201 GPPP--QGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 258 Query: 1022 SPIMNPL-GDPQSQMLQQQPSAPV-PLSSQSSFPQ--PHLPGGQPFHGVQQPLGQTGMPP 1077 P P G +SQ + P P P + + PQ P GG P P GQ PP Sbjct: 259 KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPP 318 Query: 1078 SFSKPNIEGAPGAP 1091 +P G P P Sbjct: 319 ---RPPQGGRPSRP 329 Score = 54.3 bits (129), Expect = 7e-07 Identities = 76/272 (27%), Positives = 89/272 (32%), Gaps = 35/272 (12%) Query: 850 NPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPN 909 +P+ P P P P P P +P P P GG+ P P P P Sbjct: 28 SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPP--QGGNKPQGPPPPGKP--QGPPPQ 83 Query: 910 TPYISSASSYTGQSQLYAAQ--HQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAY 967 S S G+ Q Q +Q P P PPP G Q G PP Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQ----GPPPPGKPQ 139 Query: 968 ALPP-GTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKK--------KMPENFMPPV 1018 PP G P + P + P G N P P K K P+ PP Sbjct: 140 GPPPQGDKSRSPRSP--PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPG 197 Query: 1019 PITSPIMNPLGDP--QSQMLQQQPSAPVPLSS---QSSFPQPHLPGGQPFHGVQQPLGQT 1073 P P GD SQ +P P P Q P P P G P G +P G Sbjct: 198 KPQGP--PPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG-- 253 Query: 1074 GMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTK 1105 PP KP P A G+ Q +S P K Sbjct: 254 --PPPPGKPQ---GPPAQGGSKSQSARSPPGK 280 Score = 50.1 bits (118), Expect = 1e-05 Identities = 50/184 (27%), Positives = 63/184 (34%), Gaps = 10/184 (5%) Query: 788 RAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG 847 + QG P G P+ P P+G P P G + P+ P G PPP G Sbjct: 157 KPQGPPPQGGNQPQGPPPPPGKPQGPP-PQGG--KKPQGPPPPGKPQG--PPPQGDKSRS 211 Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAY 907 + +P Q P G Q PP P +P P P G P +P PP Sbjct: 212 SQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNKPQGPPPPGKPQGPPAQGGS 269 Query: 908 PNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAY 967 + S G Q Q P PA P P + + Q GP PP Sbjct: 270 KSQSARSPPGKPQGPPQQEGNNPQGPPP---PAGGNPQQPQAPPAGQPQGPPRPPQGGRP 326 Query: 968 ALPP 971 + PP Sbjct: 327 SRPP 330 >gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] Length = 1970 Score = 61.6 bits (148), Expect = 4e-09 Identities = 73/288 (25%), Positives = 106/288 (36%), Gaps = 23/288 (7%) Query: 850 NPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQP-----YPFGTGGSAMYRPQQPVAPPTS 904 +P + PTSP + T P Y P P P + S Y P P PTS Sbjct: 1679 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1738 Query: 905 NAY-PNTP-YISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPS-SGASFQHGGPGAP 961 +Y P +P Y ++ +YT S Y+ + SPTS T P S + S+ P Sbjct: 1739 PSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYS 1798 Query: 962 PSSSAYA------LPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFM 1015 P+S +Y+ P T T + S P+S P + P + + P + Sbjct: 1799 PTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPT-S 1857 Query: 1016 PPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGM 1075 P TSP +P S S S P P P P T Sbjct: 1858 PKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYS 1917 Query: 1076 P--PSFSKPNIEGAPGAPIGNTFQ-----HVQSLPTKKITKKPI-PDE 1115 P P +S + +P +P G+T+ + + PT +T I PD+ Sbjct: 1918 PTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDD 1965 Score = 60.5 bits (145), Expect = 1e-08 Identities = 65/225 (28%), Positives = 84/225 (37%), Gaps = 32/225 (14%) Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAY 907 N +P + PTSP + T P Y P P Y P P PTS +Y Sbjct: 1747 NYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSP---------NYSPTSPSYSPTSPSY 1797 Query: 908 -PNTP-YISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSS 965 P +P Y S+ YT QS Y SSP+ SP S S+ P P+S Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYT----PSSPSYSP---------SSPSYSPTSPKYTPTSP 1844 Query: 966 AYA-LPPGTTGTLPAASEL-PASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI--- 1020 +Y+ P T T P S P T P+ P PK + P P+ Sbjct: 1845 SYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTP 1904 Query: 1021 TSPIMNPLGDPQSQML-QQQPSAPV--PLSSQSSFPQPHLPGGQP 1062 TSP +P S + P++P P S + S P PG P Sbjct: 1905 TSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSP 1949 Score = 53.1 bits (126), Expect = 2e-06 Identities = 54/199 (27%), Positives = 74/199 (37%), Gaps = 29/199 (14%) Query: 848 NVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQP-----YPFGTGGSAMYRPQQPVAPP 902 N P + PTSP + T P Y P+ P P T S Y P P P Sbjct: 1775 NYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSP 1834 Query: 903 TSNAY-PNTP-YISSASSYTGQSQLY----------AAQHQASSPTSSPATSFPPPPSSG 950 TS Y P +P Y S+ YT S Y + ++ +SPT SP T P + Sbjct: 1835 TSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTT--PKYSPTS 1892 Query: 951 ASFQHGGPGAPPSSSAYA-LPPGTTGTLPAASEL-PASQRTGPQNGWNDPPALNRVPKKK 1008 ++ P P+S Y+ P + T P S P T P+ P + P Sbjct: 1893 PTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTS- 1951 Query: 1009 KMPENFMPPVPITSPIMNP 1027 P +TSP ++P Sbjct: 1952 -------PTYSLTSPAISP 1963 Score = 38.5 bits (88), Expect = 0.039 Identities = 64/273 (23%), Positives = 89/273 (32%), Gaps = 28/273 (10%) Query: 834 HGENPPPPGF---IMHGNVNPNAAGQLPTSPG--------HMHTQVPPYPQPQP---YQP 879 HGE+ P G IM G + P G + T +P P + Sbjct: 1445 HGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFG 1504 Query: 880 AQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSP 939 + P P G G S P A P A+ + G S A+ SP SP Sbjct: 1505 SAPSPMG-GISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSP 1563 Query: 940 ATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPP 999 A S P G PG+P SS Y PG + + PA + P P Sbjct: 1564 AWSPTP----------GSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSP 1613 Query: 1000 ALNRV-PKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLP 1058 + + P ++ P P SP +P P S + P S S P Sbjct: 1614 SYSPTSPSYSPTSPSYSPTSPNYSP-TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1672 Query: 1059 GGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAP 1091 P + P + PS+S + +P +P Sbjct: 1673 PTSPSYSPTSP-SYSPTSPSYSPTSPSYSPTSP 1704 >gi|58331266 WD repeat domain 59 [Homo sapiens] Length = 974 Score = 61.2 bits (147), Expect = 6e-09 Identities = 38/137 (27%), Positives = 69/137 (50%), Gaps = 10/137 (7%) Query: 121 HTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV 180 HT + LD +F+ +L+ + + ++ IYIWD+ + P S + WN++ Sbjct: 104 HTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKD---TRKPTVALSAVAGASQVKWNKKN 160 Query: 181 QHILASASPSGRATVWDLRKNEPIIK-VSDHSNRMHCSGLAWHPDVATQMVLASEDDRLP 239 + LA+ S G +WD RK ++ ++ H +++H GL WHPD + +S+D+ Sbjct: 161 ANCLAT-SHDGDVRIWDKRKPSTAVEYLAAHLSKIH--GLDWHPDSEHILATSSQDNS-- 215 Query: 240 VIQMWDLRFASSPLRVL 256 ++ WD R L +L Sbjct: 216 -VKFWDYRQPRKYLNIL 231 Score = 30.8 bits (68), Expect = 8.2 Identities = 29/154 (18%), Positives = 59/154 (38%), Gaps = 11/154 (7%) Query: 133 FQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGR 192 F AS ++Y W + T T+ D+ W +L ++S Sbjct: 73 FAHYFAASSNQRVDLYKWKDGSGEVGTTLQGHTRVISDLD---WAVFEPDLLVTSSVDTY 129 Query: 193 ATVWDLRKN-EPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASS 251 +WD++ +P + +S + S + W+ A + + + D +++WD R S+ Sbjct: 130 IYIWDIKDTRKPTVALSAVAG---ASQVKWNKKNANCLATSHDGD----VRIWDKRKPST 182 Query: 252 PLRVLENHARGILAIAWSMADPELLLSCGKDAKI 285 + L H I + W +L + +D + Sbjct: 183 AVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSV 216 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 60.5 bits (145), Expect = 1e-08 Identities = 93/374 (24%), Positives = 130/374 (34%), Gaps = 86/374 (22%) Query: 802 IPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHG----------NVNP 851 +P E+ Q P GP H +P P ++P P + G +P Sbjct: 700 LPQERSQQPLSAEGP---HLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASP 756 Query: 852 NAAGQLPTS-----PGHMHTQVPPYPQP---QPYQPAQPYPFGTGGSAMYRPQQPVAPPT 903 A Q+P + PG + P+ P P+ P+ P+P RPQ PP+ Sbjct: 757 APAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS-PHPTRPPSRPPSRPQSVSRPPS 815 Query: 904 SNAYPNTPYISSASSYTGQSQLYAAQHQAS--SPTSSPATSFPPPPSSGASFQH------ 955 P + + G ++ Q+Q P S+PA + P PP Q Sbjct: 816 EPPLHPCPPPQAPPTLPG---IFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGP 872 Query: 956 --GGPGAPPS--SSAYALPPGTTGTLPAAS------ELPASQRTGPQNGWNDPPALNRVP 1005 P PPS SSA A T+ LPA + + P SQ GP PP L+ VP Sbjct: 873 LPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQ--GPHKSPTPPPTLHLVP 930 Query: 1006 KKKKMPENFMPPVP-----ITSP----------------------IMNPLGD----PQSQ 1034 + P PP P +T+P + N G PQ+ Sbjct: 931 EPAAPP----PPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTS 986 Query: 1035 ML---QQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAP 1091 P+A V +S Q+ P P P P+ TG+PP N A P Sbjct: 987 TSLGPLTSPAASVLVSGQAPSGTPTAPSHAP---APAPMAATGLPPLLPAENKAFASNLP 1043 Query: 1092 IGNTFQHVQSLPTK 1105 N + S P K Sbjct: 1044 TLNVAKAASSGPGK 1057 Score = 42.0 bits (97), Expect = 0.004 Identities = 56/217 (25%), Positives = 81/217 (37%), Gaps = 49/217 (22%) Query: 912 YISSASSY----TGQSQLYAAQHQASSPTSSPATSFPPPPSSGASF--QHGGPGAPPS-- 963 Y+SS+ S S+ + +S+P S PPP +HGG G PS Sbjct: 1201 YVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVT 1260 Query: 964 -SSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPP-----ALNRVPKKKKM------- 1010 + A + ++ + AAS L A + GP N PP A +R+ K K+ Sbjct: 1261 WARASSSLSSSSSSSSAASSLDADE-DGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLS 1319 Query: 1011 ---------PENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQ 1061 P + PP P T + P +P P P + Q + H P Sbjct: 1320 KVVHNTALDPVHQPPPPPATLKVAEP---------PPRPPPPPPPTGQMNGTVDHPPPAA 1370 Query: 1062 PFHGVQQPLGQTGMPPSFS-----KPNIEGAPGAPIG 1093 P ++PLG P + N+ G PGAP G Sbjct: 1371 P---ERKPLGTAPHCPRLPLRKTYRENV-GGPGAPEG 1403 Score = 41.6 bits (96), Expect = 0.005 Identities = 70/305 (22%), Positives = 96/305 (31%), Gaps = 58/305 (19%) Query: 790 QGEPVAGHESPKIPYEKQQLPKGRPGP--VAGHHQMPRVQTQQYYPH-----GENPP-PP 841 QGEP A + PK P + G+ G V P +Q + G PP PP Sbjct: 381 QGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPP 440 Query: 842 GFIMHGN----VNPNAAGQLPTS---PGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYR 894 G + +N ++ +P PG +P P Q Q P GG + Sbjct: 441 GALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAA 500 Query: 895 PQQ------------------------PVAPPTSNAYPNTPYISSASSYTGQSQLYAAQH 930 PV P S A+ + +S+A GQ L+ Q Sbjct: 501 AAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAH-SAHILSAAPIQVGQPALF--QM 557 Query: 931 QASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTG 990 S S T P P+ GP A LPP L L Sbjct: 558 PVSLAAGSLPTQSQPAPA--------GPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPA 609 Query: 991 PQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQS 1050 G P P PP +++P+ L PQ+Q Q P+ Q+ Sbjct: 610 AATG-------EAAPVLTVQPAPQAPPA-VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQA 661 Query: 1051 SFPQP 1055 + PQP Sbjct: 662 TTPQP 666 Score = 35.0 bits (79), Expect = 0.44 Identities = 63/257 (24%), Positives = 85/257 (33%), Gaps = 57/257 (22%) Query: 879 PAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTP----YISSASSYTGQSQ---------- 924 P Q P G +A Q PP++ A NTP ++ ++ TG++ Sbjct: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQ 626 Query: 925 ----------LYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTT 974 L Q QA P +P PP + G + P PP T Sbjct: 627 APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSAT 686 Query: 975 GTLPAASE-----LPASQRTGPQNGWNDPPALNRVPKK--KKMPENFMPPVPITSPIMNP 1027 T + LP + P + + P L+ VP P P P T P+ Sbjct: 687 PTAILTQDSLQMFLPQERSQQPLSA--EGPHLS-VPASVIVSAPPPAQDPAPAT-PVAKG 742 Query: 1028 LG-DPQSQMLQQQPS------APVPL-----SSQSSFP-------QPHLPGGQPFHGVQQ 1068 G PQ+ Q P+ A PL SS S P PHLP P + Sbjct: 743 AGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHP---TRP 799 Query: 1069 PLGQTGMPPSFSKPNIE 1085 P P S S+P E Sbjct: 800 PSRPPSRPQSVSRPPSE 816 >gi|50345997 E1A binding protein p300 [Homo sapiens] Length = 2414 Score = 60.1 bits (144), Expect = 1e-08 Identities = 76/298 (25%), Positives = 108/298 (36%), Gaps = 65/298 (21%) Query: 793 PVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQ----QYYPHGENPPPPGFIMHGN 848 P+ ++P + + Q G P G+ PR+Q Q+ P + P + + Sbjct: 724 PIVPRQTPPLQHHGQLAQPGALNPPMGYG--PRMQQPSNQGQFLPQTQFPSQGMNVTNIP 781 Query: 849 VNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYP 908 + P++ GQ P S M + P P P G+ GS ++ PQ P Sbjct: 782 LAPSS-GQAPVSQAQMSSSSCPVNSPI-------MPPGSQGSHIHCPQLP---------- 823 Query: 909 NTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYA 968 A HQ S SP S P P PPS A Sbjct: 824 -----------------QPALHQNSP---SPVPSRTPTPHH----------TPPSIGAQQ 853 Query: 969 LPPGTTGTLPAASELPASQRTGPQN-GWNDPPALNRVPKKKKMPENFMPPVPITSPIMNP 1027 PP TT +PA P + GPQ+ + PP P ++P+ P +P P Sbjct: 854 -PPATT--IPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQP 910 Query: 1028 LGDPQSQMLQQQPSAPVPLSSQSSF-PQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNI 1084 P+S QQ +A VP + PQP P QP ++ GQ PPS S + Sbjct: 911 QQQPRS---QQSTAASVPTPTAPLLPPQPATPLSQPAVSIE---GQVSNPPSTSSTEV 962 Score = 43.5 bits (101), Expect = 0.001 Identities = 72/281 (25%), Positives = 102/281 (36%), Gaps = 67/281 (23%) Query: 848 NVNPNAAGQLPTS--PGHMHTQVPPY-----PQPQPYQ-----PAQPYPFGTGGSA---- 891 N+ PNAAG +P S PG Q P P P P P Q P T S Sbjct: 656 NMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQF 715 Query: 892 --MYRPQQPVAPPTSNAYPNTPYISSASS------YTGQSQLYAAQHQASSPTSSPA--- 940 M Q P+ P + + ++ + Y + Q + Q Q T P+ Sbjct: 716 GQMSMAQPPIVPRQTPPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGM 775 Query: 941 --TSFPPPPSSG----ASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNG 994 T+ P PSSG + Q P +S +PPG+ G+ +LP Sbjct: 776 NVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPI--MPPGSQGSHIHCPQLPQ--------- 824 Query: 995 WNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQ 1054 PAL+ +N PVP +P P P S QQ P+ +P + Sbjct: 825 ----PALH---------QNSPSPVPSRTP--TPHHTPPSIGAQQPPATTIPAPVPT---P 866 Query: 1055 PHLPGGQPFHGVQQPLGQTGMPPSFS-----KPNIEGAPGA 1090 P +P G + P QT PP+ +P++ AP A Sbjct: 867 PAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSA 907 Score = 39.7 bits (91), Expect = 0.018 Identities = 80/358 (22%), Positives = 111/358 (31%), Gaps = 58/358 (16%) Query: 781 QLRDRLCRAQ--GEPVAGHESPKIPYEKQQLPKGRPG---------PVAGHHQMPRVQTQ 829 QL+ RL +AQ +A + + ++Q LP P P P Q Q Sbjct: 1817 QLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQ 1876 Query: 830 QYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQP------------- 876 P+ P P G V+ A T P T PP P P P Sbjct: 1877 PTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAA 1936 Query: 877 ---YQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNT----PYISSASSYTGQSQLYAAQ 929 Q A F P P+AP N P T ++ TG Q Sbjct: 1937 ETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQ-QPPW 1995 Query: 930 HQASSPTSSPATSFPPPPSSGASFQHGGP---GAPPSSSAYALPPGTTGTL--PAASELP 984 Q P S P P+ + QHG P P + P GT+ A L Sbjct: 1996 SQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLL 2055 Query: 985 ASQRTGPQNGWNDPPALN------------------RVPKKKKMPENFMPPVPITSPIMN 1026 + R+ P + L+ + P P +P P + Sbjct: 2056 RTLRS-PSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQ 2114 Query: 1027 PLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNI 1084 P P Q + P+ Q+ + LP QP +Q P+G GM P + N+ Sbjct: 2115 PPTMPGQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMG--GMSPQAQQMNM 2170 >gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sapiens] Length = 390 Score = 58.9 bits (141), Expect = 3e-08 Identities = 52/221 (23%), Positives = 95/221 (42%), Gaps = 20/221 (9%) Query: 77 YKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQN--DKHTGPVRALDVNIFQ 134 Y + ++SG L++ ++ I L+D S + K VV A+ HT V + ++ Sbjct: 146 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGK-VVDAKTIFTGHTAVVEDVSWHLLH 204 Query: 135 TNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRAT 194 +L S A++ ++ IWD + T + +++C+++N + ILA+ S Sbjct: 205 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVA 264 Query: 195 VWDLRKNEPIIKVSDHSNRMHCSGL---AWHPDVATQMVLASEDDRLPVIQMWDLRFASS 251 +WDLR +K+ HS H + W P T + + D RL V + + S Sbjct: 265 LWDLRN----LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQS 320 Query: 252 P----------LRVLENHARGILAIAWSMADPELLLSCGKD 282 P L + H I +W+ +P ++ S +D Sbjct: 321 PEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSED 361 Score = 52.8 bits (125), Expect = 2e-06 Identities = 56/249 (22%), Positives = 98/249 (39%), Gaps = 45/249 (18%) Query: 140 SGANESEIYIWDLNNFATPM---TPGAKT------QPPEDISCIAWNRQVQHILASASPS 190 S +++ I +WD++ A P AKT ED+S W+ + + S + Sbjct: 160 SASDDHTICLWDIS--AVPKEGKVVDAKTIFTGHTAVVEDVS---WHLLHESLFGSVADD 214 Query: 191 GRATVWDLRKN---EPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLR 247 + +WD R N +P V H+ ++C L+++P + S D + +WDLR Sbjct: 215 QKLMIWDTRSNNTSKPSHSVDAHTAEVNC--LSFNPYSEFILATGSADK---TVALWDLR 269 Query: 248 FASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILC--------------SNPNTG 293 L E+H I + WS + +L S G D ++ + Sbjct: 270 NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPP 329 Query: 294 EVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF 353 E+L+ +T D W P P V+ + S D + V+ + + + Sbjct: 330 ELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM---------AENIYNDEDPE 380 Query: 354 GNLDPFGTG 362 G++DP G G Sbjct: 381 GSVDPEGQG 389 >gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sapiens] Length = 424 Score = 58.9 bits (141), Expect = 3e-08 Identities = 52/221 (23%), Positives = 95/221 (42%), Gaps = 20/221 (9%) Query: 77 YKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQN--DKHTGPVRALDVNIFQ 134 Y + ++SG L++ ++ I L+D S + K VV A+ HT V + ++ Sbjct: 180 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGK-VVDAKTIFTGHTAVVEDVSWHLLH 238 Query: 135 TNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRAT 194 +L S A++ ++ IWD + T + +++C+++N + ILA+ S Sbjct: 239 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVA 298 Query: 195 VWDLRKNEPIIKVSDHSNRMHCSGL---AWHPDVATQMVLASEDDRLPVIQMWDLRFASS 251 +WDLR +K+ HS H + W P T + + D RL V + + S Sbjct: 299 LWDLRN----LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQS 354 Query: 252 P----------LRVLENHARGILAIAWSMADPELLLSCGKD 282 P L + H I +W+ +P ++ S +D Sbjct: 355 PEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSED 395 Score = 52.8 bits (125), Expect = 2e-06 Identities = 56/249 (22%), Positives = 98/249 (39%), Gaps = 45/249 (18%) Query: 140 SGANESEIYIWDLNNFATPM---TPGAKT------QPPEDISCIAWNRQVQHILASASPS 190 S +++ I +WD++ A P AKT ED+S W+ + + S + Sbjct: 194 SASDDHTICLWDIS--AVPKEGKVVDAKTIFTGHTAVVEDVS---WHLLHESLFGSVADD 248 Query: 191 GRATVWDLRKN---EPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLR 247 + +WD R N +P V H+ ++C L+++P + S D + +WDLR Sbjct: 249 QKLMIWDTRSNNTSKPSHSVDAHTAEVNC--LSFNPYSEFILATGSADK---TVALWDLR 303 Query: 248 FASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILC--------------SNPNTG 293 L E+H I + WS + +L S G D ++ + Sbjct: 304 NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPP 363 Query: 294 EVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF 353 E+L+ +T D W P P V+ + S D + V+ + + + Sbjct: 364 ELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM---------AENIYNDEDPE 414 Query: 354 GNLDPFGTG 362 G++DP G G Sbjct: 415 GSVDPEGQG 423 >gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapiens] Length = 425 Score = 58.9 bits (141), Expect = 3e-08 Identities = 52/221 (23%), Positives = 95/221 (42%), Gaps = 20/221 (9%) Query: 77 YKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQN--DKHTGPVRALDVNIFQ 134 Y + ++SG L++ ++ I L+D S + K VV A+ HT V + ++ Sbjct: 181 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGK-VVDAKTIFTGHTAVVEDVSWHLLH 239 Query: 135 TNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRAT 194 +L S A++ ++ IWD + T + +++C+++N + ILA+ S Sbjct: 240 ESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVA 299 Query: 195 VWDLRKNEPIIKVSDHSNRMHCSGL---AWHPDVATQMVLASEDDRLPVIQMWDLRFASS 251 +WDLR +K+ HS H + W P T + + D RL V + + S Sbjct: 300 LWDLRN----LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQS 355 Query: 252 P----------LRVLENHARGILAIAWSMADPELLLSCGKD 282 P L + H I +W+ +P ++ S +D Sbjct: 356 PEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSED 396 Score = 52.8 bits (125), Expect = 2e-06 Identities = 56/249 (22%), Positives = 98/249 (39%), Gaps = 45/249 (18%) Query: 140 SGANESEIYIWDLNNFATPM---TPGAKT------QPPEDISCIAWNRQVQHILASASPS 190 S +++ I +WD++ A P AKT ED+S W+ + + S + Sbjct: 195 SASDDHTICLWDIS--AVPKEGKVVDAKTIFTGHTAVVEDVS---WHLLHESLFGSVADD 249 Query: 191 GRATVWDLRKN---EPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLR 247 + +WD R N +P V H+ ++C L+++P + S D + +WDLR Sbjct: 250 QKLMIWDTRSNNTSKPSHSVDAHTAEVNC--LSFNPYSEFILATGSADK---TVALWDLR 304 Query: 248 FASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILC--------------SNPNTG 293 L E+H I + WS + +L S G D ++ + Sbjct: 305 NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPP 364 Query: 294 EVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF 353 E+L+ +T D W P P V+ + S D + V+ + + + Sbjct: 365 ELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM---------AENIYNDEDPE 415 Query: 354 GNLDPFGTG 362 G++DP G G Sbjct: 416 GSVDPEGQG 424 >gi|54860079 nadrin isoform 1 [Homo sapiens] Length = 881 Score = 58.9 bits (141), Expect = 3e-08 Identities = 79/318 (24%), Positives = 109/318 (34%), Gaps = 72/318 (22%) Query: 793 PVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNP- 851 P G SP P K + P P + Q+ Q Q G + G P Sbjct: 569 PSPGDGSP--PKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMG-------QPH 619 Query: 852 NAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGG-----SAMYRPQQPVAPPTSNA 906 NAAG P H + P P P +P P P GG ++ + P PPT + Sbjct: 620 NAAGPSP----HTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSP 675 Query: 907 YPNTPYISSASSY-TGQSQLYAAQHQAS--SPTSSPATSFPPPPSSGASFQHGGPGAPPS 963 P T + + SQL A + +S SP +P P PP+ H P + Sbjct: 676 SPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGP 735 Query: 964 SSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSP 1023 + ALP ++G P + PP T P Sbjct: 736 PNPMALP--------------------SEHGLEQP--------------SHTPPQTPTPP 761 Query: 1024 IMNPLGDPQSQMLQQQPSAPVPLSSQSSFP---QPH---LPGGQPFHGVQQPLGQTGMPP 1077 PLG +Q PS P P + P QPH LP +P V +P + +PP Sbjct: 762 STPPLG-------KQNPSLPAPQTLAGGNPETAQPHAGTLPRPRP---VPKPRNRPSVPP 811 Query: 1078 SFSKPNIEGAPGAPIGNT 1095 P + A + + NT Sbjct: 812 PPQPPGVHSAGDSSLTNT 829 Score = 54.7 bits (130), Expect = 5e-07 Identities = 55/179 (30%), Positives = 71/179 (39%), Gaps = 24/179 (13%) Query: 938 SPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWND 997 SPA P PP+ G++ GP PP SS G GT+P+++ + GP G Sbjct: 520 SPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSG-GGTVPSSAGI---LEQGPSPGDGS 575 Query: 998 PPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQML--QQQPSAPVPLSSQSSFPQP 1055 PP K K P + P P G SQ+ Q QP A S Q S QP Sbjct: 576 PP-------KPKDPVSAAVPAP---------GRNNSQIASGQNQPQAAAG-SHQLSMGQP 618 Query: 1056 HLPGGQPFHGVQQPLGQTG-MPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIP 1113 H G H +++ + + PP P G T QH SL K T+ P P Sbjct: 619 HNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSP 677 >gi|7662236 TSC22 domain family, member 2 [Homo sapiens] Length = 780 Score = 58.9 bits (141), Expect = 3e-08 Identities = 74/297 (24%), Positives = 103/297 (34%), Gaps = 39/297 (13%) Query: 827 QTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFG 886 Q Q + PPPP G ++ LP PG P P QP+QP G Sbjct: 265 QPQSFSVGQPQPPPPPV---GGAVAQSSAPLPPFPG---AATGPQPMMAAAQPSQPQGAG 318 Query: 887 TGGSAMYRPQQPVAPPTSNAYPNT-PYISSASSYTGQSQLYAAQHQASSPTSSPATSFPP 945 GG + +A P + P P + + ++ Q Y P P P Sbjct: 319 PGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYP------QPQIPPGHLLPV 372 Query: 946 PPSSGASF--QHGG---PGAP--PSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDP 998 PS + + QH P +P PSS+ A P T TLP + AS G + Sbjct: 373 QPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQ 432 Query: 999 PALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQM--LQQQPSAPVPLSSQSSFPQPH 1056 P+ P+ + P P G P + + + Q P S P P Sbjct: 433 PSEAMAPRTGPAQGGQVAP-------CQPTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQ 485 Query: 1057 LPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIP 1113 + G P V P G + P PN+ A AP V S+ T +T +P Sbjct: 486 MGGSGPLSAV--PGGPHAVVPGV--PNVPAAVPAP------SVPSVSTTSVTMPNVP 532 Score = 33.5 bits (75), Expect = 1.3 Identities = 59/218 (27%), Positives = 81/218 (37%), Gaps = 27/218 (12%) Query: 747 AAKMSQYANLLAAQGSIAAAL-AFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYE 805 AA + A L G A+++ A L ++QP+ + R AQG VA P + Sbjct: 402 AASPATAATLPVGTGQNASSVGAQLMGASSQPS-EAMAPRTGPAQGGQVA-------PCQ 453 Query: 806 KQQLPKGRPGPV---------AGHHQ-MPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAG 855 +P G V AG Q +P Q P P P ++ G N AA Sbjct: 454 PTGVPPATVGGVVQPCLGPAGAGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAV 513 Query: 856 QLPTSPGHMHTQVP----PYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTP 911 P+ P T V P P Q Q + P S + P+AP T +A + P Sbjct: 514 PAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSLP 573 Query: 912 YISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSS 949 S S + Q+Q Q + S P P PP S Sbjct: 574 Q-SDLSQFQTQTQPLVGQVDDTRRKSEP---LPQPPLS 607 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 58.5 bits (140), Expect = 4e-08 Identities = 71/298 (23%), Positives = 99/298 (33%), Gaps = 53/298 (17%) Query: 810 PKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAG--QLPTSPGHMHTQ 867 P RP P + PR H P P P+A G Q P S + Sbjct: 194 PSARPRPPT---EGPRKSVSSASEHSTTEPSPA----ARRRPSAGGGLQRPASRSLSSSA 246 Query: 868 VP--------PYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSY 919 P P + P PA P G RP Q V PP +A P +SS+ Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ-VTPPRKDAAPALGPLSSSPLA 305 Query: 920 TGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPA 979 T SP+ + A PPP ++ P +PP ++ L P + P+ Sbjct: 306 T------------PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353 Query: 980 ASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNP-LGDPQSQMLQQ 1038 LP+ T P PP++ P + +PP+ + + +P L P S + Sbjct: 354 LQTLPSPPATPPSQA---PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410 Query: 1039 QPSAPVPLSS-----------------QSSFPQPHLPGGQPFHG--VQQPLGQTGMPP 1077 A L S Q+S P P P +Q PL PP Sbjct: 411 SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468 Score = 56.6 bits (135), Expect = 1e-07 Identities = 85/313 (27%), Positives = 108/313 (34%), Gaps = 49/313 (15%) Query: 833 PHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHT---QVPP---------YPQPQPYQPA 880 PH E PP P P +P + T Q PP P P A Sbjct: 556 PHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA 615 Query: 881 QPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPA 940 P P A+ Q P +PP S P +P + + ++ Q S P S P Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASP--PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 673 Query: 941 TS-FPPPPSSGASFQHGGPG-APPSSSAYAL-----PPGTTGTLPAAS---ELPASQRTG 990 + F PP S S P APPS +A L PP + P+A+ + P Sbjct: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733 Query: 991 PQNGWNDPPAL----------NRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQM----- 1035 P PPA RVP P +PP P S M+PL P Q Sbjct: 734 PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793 Query: 1036 ---LQQQPSAPVPLSSQSSF-PQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAP 1091 LQ PS P Q+ F P L P + P Q PP + P ++ P P Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASL----PMSPLATPPPQA--PPVLAAPLLQVPPSPP 847 Query: 1092 IGNTFQHVQSLPT 1104 T Q + PT Sbjct: 848 ASPTLQAPRRPPT 860 Score = 47.4 bits (111), Expect = 8e-05 Identities = 57/202 (28%), Positives = 76/202 (37%), Gaps = 31/202 (15%) Query: 896 QQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSP----ATSFP---PPPS 948 Q P A T+ N P ++ T + L H + P +P A P PPP Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPL-TTPHLETPPCPAPCPLQAPPSPLTTPPPE 582 Query: 949 SGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKK 1008 + +S P APP A A PP L P S P PP + P Sbjct: 583 TPSSIATPPPQAPP---ALASPP-----LQGLPSPPLSPLATP------PP---QAPPXL 625 Query: 1009 KMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSF-PQPHLPGGQPFH-GV 1066 +P PP P SP ++PL P Q P+A Q+ F P P P PF Sbjct: 626 ALPPLQAPPSPPASPPLSPLATPS----PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681 Query: 1067 QQPLGQTGMPPSFSKPNIEGAP 1088 P+ + PPS + P++ P Sbjct: 682 SPPVSPSATPPSQAPPSLAAPP 703 Score = 43.5 bits (101), Expect = 0.001 Identities = 48/173 (27%), Positives = 61/173 (35%), Gaps = 24/173 (13%) Query: 839 PPPGFIMHGNVNPNAAGQLPTSPGHMHT-QVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQ 897 PPP V P+ P SP +VPP P Q P S + +P Sbjct: 727 PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP- 785 Query: 898 PVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPP---------PPS 948 P APP P S +S+ GQ+ + SP ++P PP PPS Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845 Query: 949 SGASFQHGGPGAPPSSS----------AYALPPGTTGTLPAASELPASQRTGP 991 AS P PP+ AL PG P S P+S +GP Sbjct: 846 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGP 895 Score = 36.6 bits (83), Expect = 0.15 Identities = 52/190 (27%), Positives = 60/190 (31%), Gaps = 36/190 (18%) Query: 849 VNPNAAGQLPTSP-GHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQ-----QPVAPP 902 V P+ LP SP Q PP P Q P G A + P P+A P Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827 Query: 903 TSNAYP--NTPYISSASSYTGQSQLYAAQHQASSPTSSPATSF-------------PPPP 947 A P P + S L A + PT P TS PPPP Sbjct: 828 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRP---PTPGPDTSVSGPRLTLALAPGPPPPP 884 Query: 948 SSGASFQHGGPG-APPSSSAYALPP-----------GTTGTLPAASELPASQRTGPQNGW 995 S S GP A SSSA + P G + P +EL A G Sbjct: 885 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 944 Query: 996 NDPPALNRVP 1005 P A P Sbjct: 945 APPLAFRGAP 954 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 58.5 bits (140), Expect = 4e-08 Identities = 91/356 (25%), Positives = 138/356 (38%), Gaps = 47/356 (13%) Query: 790 QGEPVAGHESPKIPYEKQQLP-KGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGN 848 QG+P GH + P E L + +P AG P+++ PPP Sbjct: 393 QGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPE----ESP 448 Query: 849 VNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRP--QQPVAPPTSNA 906 ++P + PTSP +++ P P+ P A P P S RP + P++PP + Sbjct: 449 LSPPPE-ESPTSPPPEASRLSPPPEELP---ASPLPEALHLS---RPLEESPLSPPPEES 501 Query: 907 YPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGAS--FQHGGPGAPPSS 964 + P SS S +S L + SP S PPP +S S F+ PP Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLS-PPPEASPLSPPFEESPLSPPPEE 560 Query: 965 SAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRV-------PKKKKMPENFMPP 1017 + PP + P E P S ++ + PP +R+ P E+ + P Sbjct: 561 LPTSPPPEASRLSPPPEESPMSP-PPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP 619 Query: 1018 VPITSPIMNPLGD-PQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPL------ 1070 P S + P D P S ++ P +P P S+ S P P + P + PL Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS-PLPVVSRLSP-PPEESPLSPPPEE 677 Query: 1071 GQTGMPPSFSK-----------PNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDE 1115 T PP S+ P E +P +P + SLP ++ P+P+E Sbjct: 678 SPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE--DSLMSLPLEESPLLPLPEE 731 Score = 52.4 bits (124), Expect = 3e-06 Identities = 87/343 (25%), Positives = 117/343 (34%), Gaps = 68/343 (19%) Query: 764 AAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESP-----KIPYE-KQQLPKGRPGPV 817 AA F+ T + D + V G +SP K+P + Q+P P + Sbjct: 2120 AAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGL 2179 Query: 818 AGHHQM-PRVQTQQ--YYPH----GENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPP 870 A + + PR T Y P+ G PP M G + AGQ PG HT P Sbjct: 2180 APAYPLEPRFPTAPPTYPPYPSPTGAPAQPP---MLGASSRPGAGQ----PGEFHTTPPG 2232 Query: 871 YPQPQPYQP-------------------------------AQPYPFGTGGSAM-YRPQQP 898 P+ QP P P PFG A+ + ++ Sbjct: 2233 TPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEEL 2292 Query: 899 VAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGP 958 A S PN ++ S SS T L +P S P S G + P Sbjct: 2293 GASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLR---P 2349 Query: 959 GAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENF--MP 1016 PP + A A P+ P R G P L P+ PE+ +P Sbjct: 2350 QEPPPAQALA---------PSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP-PESCCALP 2399 Query: 1017 PVPITS-PIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLP 1058 P + S P PQSQ Q P P PLS+++ P P P Sbjct: 2400 PRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTP 2442 Score = 50.8 bits (120), Expect = 8e-06 Identities = 69/251 (27%), Positives = 92/251 (36%), Gaps = 44/251 (17%) Query: 858 PTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPN------TP 911 P SPG + ++PP P Q PFG + P+ P APPT YP+ P Sbjct: 2153 PDSPGELFLKLPPQV---PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQP 2209 Query: 912 YISSASSYTGQSQ--------LYAAQHQASSP--------TSSPATSFPPPPSSGASFQH 955 + ASS G Q +HQ S+P S + P P G Sbjct: 2210 PMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG----- 2264 Query: 956 GGPGAPPSSSAYALPPGTTGTLPAASELPASQRT-GPQN-GWNDPPA--LNRVPKKKKMP 1011 GG + P S EL AS + GP N G+ D P+ + + K P Sbjct: 2265 GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTP 2324 Query: 1012 ENFMPPV-PITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPH----LPGGQPFHGV 1066 + F P+ P S + +PQS L +P P P + + P H PG Sbjct: 2325 DVFKAPLTPRASQV-----EPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYA 2379 Query: 1067 QQPLGQTGMPP 1077 Q PL PP Sbjct: 2380 QPPLTPRPQPP 2390 Score = 40.4 bits (93), Expect = 0.010 Identities = 67/263 (25%), Positives = 91/263 (34%), Gaps = 47/263 (17%) Query: 840 PPGFIMHGNVNPNAAGQLPTSPGHMHTQVP-----PYPQPQPYQPAQPYPFGTG-----G 889 PP F V G +P M P P +P QP P P G G Sbjct: 2515 PPNF-----VRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPG 2569 Query: 890 SAMYRPQQP-VAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPP- 947 + +PQ T N +P+ + +S TG+S SP P+ PP P Sbjct: 2570 PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESY-------GLSPLRPPSVLPPPAPD 2622 Query: 948 ------SSGASFQHGGPGAPPSSSAYALPPGT-TGTLPAASELPASQRTGPQNGWNDPPA 1000 S GAS Q G +P PGT G+ A +ELP +Q G Sbjct: 2623 GSLPYLSHGAS-QRSGITSPVEKRE---DPGTGMGSSLATAELPGTQDPGMSG------- 2671 Query: 1001 LNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQP----H 1056 L++ +K+ + + I I + + A P S + P Sbjct: 2672 LSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQ 2731 Query: 1057 LPGGQ-PFHGVQQPLGQTGMPPS 1078 L GQ PF G Q G+PPS Sbjct: 2732 LSRGQTPFAGTQDKSSLVGLPPS 2754 Score = 39.7 bits (91), Expect = 0.018 Identities = 63/269 (23%), Positives = 91/269 (33%), Gaps = 42/269 (15%) Query: 837 NPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQP------AQPYPFGTGGS 890 +PPP +M + + LP P P+ P+P +P +P+ Sbjct: 708 SPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEE 767 Query: 891 AMYRPQQPVAPPTSNAYPNTPYISSASS---YTGQSQLYAAQHQASSPTSSPATS----F 943 PQ P A P P++S + + Q + Q P SP Sbjct: 768 PHLSPQPE--EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS 825 Query: 944 PPPPSSGASFQHGGP---------------GAPPSSSAYALPPGTTGTLPAASELPASQR 988 P P S S Q P PP S PP G PA ELP Sbjct: 826 PQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP 885 Query: 989 TGPQNGWNDPPALNRVPKKKKMPENFMPPV-PITSPI-MNPLGDPQ-SQMLQQQPSAPVP 1045 G P+L+ + + + E PP+ P+ + ++P G+P S L P P Sbjct: 886 PG-------EPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPP 938 Query: 1046 LSSQSSFPQPHLPGGQPFHGVQQPLGQTG 1074 LS + P P P ++ P G G Sbjct: 939 LSPIITAAAP--PALSPLGELEYPFGAKG 965 Score = 35.0 bits (79), Expect = 0.44 Identities = 37/152 (24%), Positives = 52/152 (34%), Gaps = 20/152 (13%) Query: 957 GPGAPPSSSAYALPPGTTG-----------TLPAASELPASQRTGPQNGWNDPPALNRVP 1005 GPG P + PG G T+ A A++ GP P A+ P Sbjct: 3998 GPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE--GPSTHQGGPLAIGTTP 4055 Query: 1006 KKKKM-PENFMPPVPITSPIM--NPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQP 1062 + P P + S ++ P PQ LQ QP +P Q H GG Sbjct: 4056 ESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG-- 4113 Query: 1063 FHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGN 1094 G LG + S P++ P +G+ Sbjct: 4114 --GSHGQLGSGSSSEASSVPHLLAQPSVSLGD 4143 Score = 32.7 bits (73), Expect = 2.2 Identities = 43/159 (27%), Positives = 53/159 (33%), Gaps = 26/159 (16%) Query: 922 QSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAAS 981 Q QL A Q S PP +Q G P G G P Sbjct: 4219 QQQLQALLMQRQLQQSQAVRQTPP-------YQEPGTQTSPLQ-------GLLGCQPQLG 4264 Query: 982 ELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPI-TSPIMNPLGDPQSQMLQQQP 1040 P Q TGP L P+ + P PP + T P++ P+ Q+P Sbjct: 4265 GFPGPQ-TGPLQ------ELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEP 4317 Query: 1041 SAPVPLSSQSSF--PQPHLPGGQPFHGVQQPLGQTGMPP 1077 P L S SS + LP P G +P G T PP Sbjct: 4318 KRPSQLPSPSSQLPTEAQLPPTHP--GTPKPQGPTLEPP 4354 Score = 31.6 bits (70), Expect = 4.8 Identities = 52/233 (22%), Positives = 73/233 (31%), Gaps = 29/233 (12%) Query: 822 QMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQ----VPPYPQPQPY 877 Q P ++ G PP PG ++ G +PT G + Q + PQ + Sbjct: 4156 QQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPT-VGQLRAQLQGVLAKNPQLRHL 4214 Query: 878 QPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQ-LYAAQHQASSPT 936 P Q M R Q S A TP + T Q L Q Sbjct: 4215 SPQQQQQL--QALLMQRQLQ-----QSQAVRQTPPYQEPGTQTSPLQGLLGCQ------- 4260 Query: 937 SSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWN 996 P P P +G + G P PPG T P L T P + Sbjct: 4261 --PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPV---LGPVHPTPPPSSPQ 4315 Query: 997 DPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQ 1049 +P +++P P + +P P PQ L+ P P ++Q Sbjct: 4316 EPKRPSQLPS----PSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQ 4364 >gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo sapiens] Length = 421 Score = 58.5 bits (140), Expect = 4e-08 Identities = 51/202 (25%), Positives = 96/202 (47%), Gaps = 18/202 (8%) Query: 143 NESEIYIWDLNNFATPMTPGAKTQPPEDISC--IAWNR----QVQHILASASPSGRATVW 196 N+ +I D + + G+ P + C I W+R Q Q +LA+ +GR +W Sbjct: 97 NKPREHIIDCGDIVWSLAFGSSV-PEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIW 155 Query: 197 DLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVL 256 D+ + ++ + DH+ + L + PD + +V AS D L ++WDL+ + ++VL Sbjct: 156 DVYTGKLLLNLVDHTEVVR--DLTFAPDGSLILVSASRDKTL---RVWDLKDDGNMMKVL 210 Query: 257 ENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNP 316 H + + A+S D +L S G + N + ++ +L + D+ C +P Sbjct: 211 RGHQNWVYSCAFS-PDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHH---DVVACDFSP 266 Query: 317 --AVLSAASFDGRISVYSIMGG 336 A+L+ AS+D R+ ++ G Sbjct: 267 DGALLATASYDTRVYIWDPHNG 288 Score = 44.3 bits (103), Expect = 7e-04 Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 12/163 (7%) Query: 137 LVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVW 196 L+A+G N I IWD+ + T+ D++ + IL SAS VW Sbjct: 142 LLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLT---FAPDGSLILVSASRDKTLRVW 198 Query: 197 DLRKNEPIIKV-SDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV 255 DL+ + ++KV H N ++ A+ PD + + + + +W++ + +R Sbjct: 199 DLKDDGNMMKVLRGHQNWVY--SCAFSPDSSMLCSVGAS----KAVFLWNMD-KYTMIRK 251 Query: 256 LENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYE 298 LE H ++A +S D LL + D ++ +P+ G++L E Sbjct: 252 LEGHHHDVVACDFS-PDGALLATASYDTRVYIWDPHNGDILME 293 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 58.5 bits (140), Expect = 4e-08 Identities = 88/338 (26%), Positives = 115/338 (34%), Gaps = 34/338 (10%) Query: 793 PVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPN 852 P G +P P P P G P + P P P G + +P Sbjct: 1159 PKGGLATPP-PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL--ATPSPK 1215 Query: 853 AAGQLP--TSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNT 910 A P T P P P+ P PA P GG A P+ PP + P+ Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP-PSL 1274 Query: 911 PYISSASSYTGQSQ--LYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYA 968 + + G + P +SP P PP++ G PG PP A Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334 Query: 969 LP------PGTTGTLPAASELPASQRTGPQNGWN-DPPALNRVPKKKKMPENFMPPVPIT 1021 P P T TLPA + T P + PPA P K P PP P Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA--ATPSHKGGPA-MTPPSPKR 1391 Query: 1022 SP-IMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFS 1080 P I +P GDP S A +PLS + + P P + G P PP+ + Sbjct: 1392 GPAIPSPKGDPTS-------PAVIPLSPKKA---PATPVTR--EGAATPSKGDLTPPAVT 1439 Query: 1081 KPNIEGAP--GAPIGN-TFQHVQSLPTKKITKKPIPDE 1115 +++ AP AP G + PT P P E Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477 Score = 56.2 bits (134), Expect = 2e-07 Identities = 82/324 (25%), Positives = 104/324 (32%), Gaps = 44/324 (13%) Query: 790 QGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNV 849 +G P +P P PK P P + P+ G P P ++ Sbjct: 862 KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK--------EGPATPAPKQAPALSM 913 Query: 850 NPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGG----SAMYRPQQPVA-PPTS 904 ++ + +P P P+ P PA P GG S + P P A PP+ Sbjct: 914 TSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP 973 Query: 905 NAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPAT----SFPPPPSSGASFQHGGPGA 960 P TP A + + SP PAT P PP+ G P A Sbjct: 974 KGGPATPSPKGAPTPPAAT--------PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025 Query: 961 PP-----SSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKK--KMPEN 1013 P S+ A PP G+ PAA+ LP T P P P K P Sbjct: 1026 TPFPKGASTPPAATPPSPKGS-PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084 Query: 1014 FMPPVPITSPIM-NPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGG--QPFHGVQQPL 1070 PP P P +P G P P A P S + P G P P Sbjct: 1085 ATPPSPKGGPATPSPKGAP-------MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137 Query: 1071 GQTGMPPSFSKPNIEGA-PGAPIG 1093 G PP P A P +P G Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKG 1161 Score = 53.5 bits (127), Expect = 1e-06 Identities = 73/290 (25%), Positives = 94/290 (32%), Gaps = 35/290 (12%) Query: 810 PKGRPGPVAGHHQMPRVQTQQYYPHGENPPP---PGFIMHGNVNPNAAGQLPTSPGHMHT 866 PKG P P A P+ P PP P G P+ G PT P Sbjct: 936 PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGA-PTPPA---- 990 Query: 867 QVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLY 926 PP P+ P A P P G P P P + +P A++ Sbjct: 991 ATPPSPKGGP---ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047 Query: 927 AAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPAS 986 AA ++PA + P P GGP A PS PP T P S Sbjct: 1048 AATPLPKGAPTTPAATLPSP--------KGGP-ATPSLKGAPTPPAATPPSPKGGPATPS 1098 Query: 987 QRTGPQNGWNDPPALNRVPKKKKM---PENFMPPVPITSPIMNPLGDPQSQMLQQQPSAP 1043 + P PPA K + P P P +P +P G + + P+ P Sbjct: 1099 PKGAPM-----PPAATPPSPKGGLATPPHKGAPTTPAATP-PSPKGGLATPPPKGAPTTP 1152 Query: 1044 --VPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAP 1091 P S + P P G P P G + P+ +GAP P Sbjct: 1153 AATPPSPKGGLATPP-PKGAPTTPAATPPSPKG---GLATPSPKGAPTTP 1198 Score = 53.5 bits (127), Expect = 1e-06 Identities = 78/324 (24%), Positives = 108/324 (33%), Gaps = 54/324 (16%) Query: 810 PKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVP 869 PKG P P A P+ P G PP P P+S G T Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT--- 1362 Query: 870 PYPQPQPYQPAQPYPFGTGGSAMYRPQ--------QPVAPPTSNAY-PNTPYISSASSYT 920 P + P PA P GG AM P P PTS A P +P + A+ T Sbjct: 1363 PSSKEGPTPPAAT-PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVT 1421 Query: 921 GQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALP---------- 970 + ++ + P +P + P +S GGP P S LP Sbjct: 1422 REGAATPSKGDLTPPAVTPVSLKKAPATSAPK---GGPATPSSKGDPTLPAVTPPSPKEP 1478 Query: 971 --------------------PGTTGTLPAASELPASQRTGPQ--NGWNDPPALNRVPKKK 1008 P TLPA +P+S + P + DP A K Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAV--IPSSPKEVPATPSSRRDPIAPTATLLSK 1536 Query: 1009 KMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAP-VPLSSQSSFPQPHLPGGQPFHGVQ 1067 K P P + P M ++ + AP P S ++S P P + G Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP--STYKGAP 1594 Query: 1068 QPLGQTGMPPSFSKPNIEGAPGAP 1091 P + +PP+ + P+ + AP P Sbjct: 1595 SP-KELLIPPAVTSPSPKEAPTPP 1617 Score = 52.8 bits (125), Expect = 2e-06 Identities = 86/324 (26%), Positives = 110/324 (33%), Gaps = 49/324 (15%) Query: 789 AQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGN 848 A P A SPK LPKG P A P+ P P + G Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK----------GGPATPS--LKGA 1079 Query: 849 VNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYP 908 P AA T P P P+ P PA P GG A P AP T A P Sbjct: 1080 PTPPAA----TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT--PPHKGAPTTPAATP 1133 Query: 909 NTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYA 968 +P A+ A A++P S PPP + P +P A Sbjct: 1134 PSPKGGLATP----PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189 Query: 969 LPPGTTGTLPAASELPASQRTG-----PQNGWNDPPALNRVPK---KKKMPENFMPPVPI 1020 P G T PAA+ P S + G P+ P A PK P+ P P Sbjct: 1190 SPKGAP-TTPAAT--PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG-APTTPA 1245 Query: 1021 TSPIMNPLGDPQSQMLQQQPSAP--VPLSSQSSFPQPHLPGGQPFHGVQQPLGQTG---- 1074 +P +P G P + + P+ P P S + P G P V P G Sbjct: 1246 ATP-PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA-PNPAVVTPPSPKGGPAT 1303 Query: 1075 -------MPPSFSKPNIEGAPGAP 1091 PP+ + P+ +G+PG P Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTP 1327 Score = 46.6 bits (109), Expect = 1e-04 Identities = 61/232 (26%), Positives = 82/232 (35%), Gaps = 25/232 (10%) Query: 877 YQPAQPYPFGTGGSAMYRPQQPVAPPTS--NAYPNTPYISSASSYTGQSQLYAAQHQASS 934 Y P P G S Q PPT +A P+TP + +S + + ++ S Sbjct: 789 YLADSPSPLGVSVSP-----QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF 843 Query: 935 PTS--SPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGT-----LPAASELPAS- 986 S SPAT+ P P S P S LPP T T LP E PA+ Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903 Query: 987 ---QRTGPQNGWNDPPALNRVPKKKKMPENFMP---PVPITSPIMNPLGDPQSQMLQQQP 1040 Q + P P K +P + P P P + +P G P + + P Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963 Query: 1041 SAPVPL-SSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAP 1091 + P S P P G P P G P + P+ +GAP P Sbjct: 964 TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP---ATPSPKGAPTPP 1012 Score = 44.3 bits (103), Expect = 7e-04 Identities = 65/295 (22%), Positives = 102/295 (34%), Gaps = 39/295 (13%) Query: 800 PKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPT 859 P +P PK P P Q+ + + P P P G V P++ ++P Sbjct: 1465 PTLPAVTPPSPKEPPAP----KQVATSSSPKKAP--ATPAPMGAPTLPAVIPSSPKEVPA 1518 Query: 860 SPGHMHTQVPPY-------------PQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNA 906 +P + P P+ PA P A+ P++ A P+S Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKE 1578 Query: 907 YPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSA 966 + P ++ S+Y G + + SP P PP+ GP P Sbjct: 1579 ASSPPAVTP-STYKGAPSPKELLIPPAVTSPSPK-EAPTPPAVTPPSPEKGPATPAPKGT 1636 Query: 967 YALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKK---KMPENFMPPVPITSP 1023 PP T +L + PAS + G P A +P KK + E + P P ++P Sbjct: 1637 PTSPPVTPSSLKDSPTSPASVTC--KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP 1694 Query: 1024 IMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHL-PGGQPFHGVQQPLGQTGMPP 1077 I+ P+ P + +SS P + P +G + PL P Sbjct: 1695 IIT------------APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP 1737 Score = 35.0 bits (79), Expect = 0.44 Identities = 43/179 (24%), Positives = 64/179 (35%), Gaps = 30/179 (16%) Query: 874 PQPYQPAQPYPFGT--GGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQ 931 P P P Q T G A + P+ P+APP S A +TP ++ A + Sbjct: 1735 PAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKA--STPLTAA-----------AFEKV 1781 Query: 932 ASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGP 991 P S+ ++ P PP S P PP PG P+ PA Sbjct: 1782 LPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA------ 1835 Query: 992 QNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQS 1050 ++ L +P PE VP S ++N + + PSA P++ + Sbjct: 1836 ----DEDELLPLIP-----PEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNN 1885 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.131 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 54,634,602 Number of Sequences: 37866 Number of extensions: 3191316 Number of successful extensions: 20964 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 134 Number of HSP's successfully gapped in prelim test: 1506 Number of HSP's that attempted gapping in prelim test: 11912 Number of HSP's gapped (non-prelim): 6328 length of query: 1220 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1106 effective length of database: 13,930,794 effective search space: 15407458164 effective search space used: 15407458164 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.