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Search of human proteins with 239741684
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
(1524 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 2956 0.0
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 2268 0.0
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 1831 0.0
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 1541 0.0
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 1490 0.0
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 921 0.0
gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 863 0.0
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 613 e-175
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 561 e-159
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 528 e-149
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 528 e-149
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 528 e-149
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 380 e-105
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 371 e-102
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 317 6e-86
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 249 1e-65
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 249 1e-65
gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 235 2e-61
gi|169217530 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 224 5e-58
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 215 2e-55
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 215 2e-55
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 215 2e-55
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 213 1e-54
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 209 2e-53
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 209 2e-53
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 209 2e-53
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 199 2e-50
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 199 2e-50
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 199 2e-50
gi|239754871 PREDICTED: similar to Coiled-coil domain-containing... 124 9e-28
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 2956 bits (7664), Expect = 0.0
Identities = 1524/1524 (100%), Positives = 1524/1524 (100%)
Query: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ
Sbjct: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
Query: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY
Sbjct: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
Query: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV
Sbjct: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
Query: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL
Sbjct: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
Query: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS
Sbjct: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
Query: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGG 360
QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGG
Sbjct: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGG 360
Query: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN
Sbjct: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
Query: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS
Sbjct: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
Query: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
DEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQK
Sbjct: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
Query: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEK 600
PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEK
Sbjct: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEK 600
Query: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA
Sbjct: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
Query: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDK 720
RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDK
Sbjct: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDK 720
Query: 721 EDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQP 780
EDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQP
Sbjct: 721 EDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQP 780
Query: 781 AWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQS 840
AWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQS
Sbjct: 781 AWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQS 840
Query: 841 AQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTST 900
AQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTST
Sbjct: 841 AQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTST 900
Query: 901 PAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKN 960
PAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKN
Sbjct: 901 PAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKN 960
Query: 961 VILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRI 1020
VILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRI
Sbjct: 961 VILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRI 1020
Query: 1021 SEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEA 1080
SEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEA
Sbjct: 1021 SEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEA 1080
Query: 1081 DVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQ 1140
DVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQ
Sbjct: 1081 DVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQ 1140
Query: 1141 NLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQR 1200
NLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQR
Sbjct: 1141 NLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQR 1200
Query: 1201 ESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILS 1260
ESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILS
Sbjct: 1201 ESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILS 1260
Query: 1261 LQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTME 1320
LQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTME
Sbjct: 1261 LQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTME 1320
Query: 1321 KCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRL 1380
KCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRL
Sbjct: 1321 KCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRL 1380
Query: 1381 LLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSR 1440
LLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSR
Sbjct: 1381 LLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSR 1440
Query: 1441 HCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKK 1500
HCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKK
Sbjct: 1441 HCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKK 1500
Query: 1501 QDDQIERLEKILQHSSLMLQVFES 1524
QDDQIERLEKILQHSSLMLQVFES
Sbjct: 1501 QDDQIERLEKILQHSSLMLQVFES 1524
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 2268 bits (5876), Expect = 0.0
Identities = 1228/1532 (80%), Positives = 1286/1532 (83%), Gaps = 110/1532 (7%)
Query: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
MVQILKNAASVFSETTSLEVSSQKQPALKDTSDK+DSVSNTATEIKDEQKSGTVLPAVEQ
Sbjct: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQ 60
Query: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
CLNRSLYRPDAVAQPVTE+EF+LESEIISKLYIPKRKIISPRSI+DVLPPVEEAVDRCLY
Sbjct: 61 CLNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLY 120
Query: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
LLDRFAQ VTKDKFALESENISEPYFTNRRTISQQSAE LDAACGIDKTENG +FEDQNV
Sbjct: 121 LLDRFAQAVTKDKFALESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNV 180
Query: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
DKEGKALPATGQKANVSP E+PPL T
Sbjct: 181 DKEGKALPATGQKANVSP----------------------------------EQPPLFTH 206
Query: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
T+K++D S + DS ++S ++ +E+ P+S
Sbjct: 207 TVKDSDHISTRFLGSMDS-----LTSSEESSERP------------------PLSTLTLK 243
Query: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGG 360
+ P+ KA KDS
Sbjct: 244 EADPSSKAAMRRKDSPP------------------------------------------- 260
Query: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
G VSSQKQPA KATSD DS NIATEIK+G GTVSSQKQPA KAT+DE+DSVSN
Sbjct: 261 --PGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 318
Query: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
IATEIK+G++SGTVS QKQ A K +K S+ NIAT I G KSGTVSSQK P ATS
Sbjct: 319 IATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATS 378
Query: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
D+ S L+IA E KDG + TVSS+K+PALKAT+DE+DS SNI KDGE S VSSQK
Sbjct: 379 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 438
Query: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEK 600
P LK T+DEEDSVL IA E KDGEKS TVSS+K P LKA++ E+DSV IA KDGEK
Sbjct: 439 QPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK 498
Query: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
+ VSSRKKP+L+ATSDEKDSFSNITREKKDGEISR VSSQKPPALK TSDEEDSVL IA
Sbjct: 499 SGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIA 558
Query: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDK 720
RE KDGEKSRTVSSE+PPGLKAT DEKDS+LNIARGKK GEKTR VSS KQPALKA DK
Sbjct: 559 REEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDK 618
Query: 721 EDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQP 780
E+SVPNMATE KDEQISGTVS QKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ
Sbjct: 619 ENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQL 678
Query: 781 AWKATSVKKDSVSNIATEIKDGQIRGT------GILEYTFNVM--FDQIEEKFTSLNKSA 832
AWKATSVKKDSVSNIATEIKDGQIRGT L+ T + I + KS
Sbjct: 679 AWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSG 738
Query: 833 GVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATK 892
VSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATK
Sbjct: 739 TVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATK 798
Query: 893 MKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGD 952
MKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGD
Sbjct: 799 MKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGD 858
Query: 953 SLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNK 1012
SLCCNCKNVILLIDQHEMKCKDCVHLLKIK TFCL KRL +LKDNHCEQLRVKIRKLKNK
Sbjct: 859 SLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNK 918
Query: 1013 ASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRIT 1072
ASVLQKR+SEKEEIKSQLKHE LELEKELCSLRFAIQQEKKKRRNVEE+HQKVREKLRIT
Sbjct: 919 ASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRIT 978
Query: 1073 EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRL 1132
EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRL
Sbjct: 979 EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRL 1038
Query: 1133 EKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTL 1192
EKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRN ETLA+TIACYSGQLAALTDENTTL
Sbjct: 1039 EKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTL 1098
Query: 1193 RSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENL 1252
RSKLEKQRES QRLETEMQSY CRLNAA CDHDQSHSSKRDQELAFQGTVDKC HLQENL
Sbjct: 1099 RSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENL 1158
Query: 1253 NSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMY 1312
NSHVLILSLQLSKAESK RVL+TELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMY
Sbjct: 1159 NSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMY 1218
Query: 1313 KSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQ 1372
KSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARV+NLQ
Sbjct: 1219 KSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQ 1278
Query: 1373 AECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATK 1432
AECRKHRLLLEEDNKMLVNELNHSKEK+CQYEKEKAEREVAVRQLQQK+DDVLNK SATK
Sbjct: 1279 AECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATK 1338
Query: 1433 ALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHV 1492
ALLDASSRHC YLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGD QKLEVE+V
Sbjct: 1339 ALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENV 1398
Query: 1493 MMRKIIKKQDDQIERLEKILQHSSLMLQVFES 1524
MMRKIIKKQD+QIER EKILQHSSLMLQVFES
Sbjct: 1399 MMRKIIKKQDEQIERFEKILQHSSLMLQVFES 1430
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 1831 bits (4743), Expect = 0.0
Identities = 968/1099 (88%), Positives = 1000/1099 (90%), Gaps = 8/1099 (0%)
Query: 434 VSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIAREN 493
+S QKQ A KAT+D+KDSVSNIATEIK+G SGTVSSQK PA ATSDE+ SV +IA E
Sbjct: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
Query: 494 KDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDS 553
K+G++S TVS +K+ A K +K S NI G S VSSQK P K SD+ DS
Sbjct: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
Query: 554 VLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLE 613
L A E KDG + TVSS+K LKA++ E+ SV NIA KDGEK+ VSS+KKP+L+
Sbjct: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
Query: 614 ATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVS 673
ATSDEKDSFSNITREKKDGEISR VSSQKPPALK TS +EDSVL IARE KDGEKSRTVS
Sbjct: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262
Query: 674 SEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKD 733
E+PPGLKAT DEKDS+LNIARGKKDGEKTR VSS KQP+LKA DKEDSVPNMATE KD
Sbjct: 263 FEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKD 322
Query: 734 EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 793
EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS
Sbjct: 323 EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 382
Query: 794 NIATEIKDGQIRGT------GILEYTFNVM--FDQIEEKFTSLNKSAGVSPQKQSAQKVI 845
NIATEIKDGQIRGT L+ T + I + KS VSPQKQSAQKVI
Sbjct: 383 NIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI 442
Query: 846 FKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQD 905
FKKKVSLLNIATRITGG KSGTEYPENL TLKATIENK+SVLNTATKMK+VQTSTPAEQD
Sbjct: 443 FKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQD 502
Query: 906 LEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLI 965
LEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLI
Sbjct: 503 LEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLI 562
Query: 966 DQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEE 1025
DQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEE
Sbjct: 563 DQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEE 622
Query: 1026 IKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKP 1085
IKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEE+HQKVREKLRITEEQYRIEADVTKP
Sbjct: 623 IKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKP 682
Query: 1086 IKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKK 1145
IKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKK
Sbjct: 683 IKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKK 742
Query: 1146 YLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQR 1205
YLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQR
Sbjct: 743 YLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQR 802
Query: 1206 LETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSK 1265
LETEMQSY CRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSK
Sbjct: 803 LETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSK 862
Query: 1266 AESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK 1325
AESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK
Sbjct: 863 AESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK 922
Query: 1326 QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEED 1385
QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEED
Sbjct: 923 QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEED 982
Query: 1386 NKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYL 1445
NKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYL
Sbjct: 983 NKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYL 1042
Query: 1446 ENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQI 1505
ENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQI
Sbjct: 1043 ENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQI 1102
Query: 1506 ERLEKILQHSSLMLQVFES 1524
ERLEKILQHSSLMLQVFES
Sbjct: 1103 ERLEKILQHSSLMLQVFES 1121
Score = 631 bits (1627), Expect = e-180
Identities = 481/1201 (40%), Positives = 639/1201 (53%), Gaps = 154/1201 (12%)
Query: 263 KVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 322
++S QKQ AEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE
Sbjct: 22 ELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 81
Query: 323 IKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTD 382
IK+GQQSGTVSPQKQSA KVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASK SDKTD
Sbjct: 82 IKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTD 141
Query: 383 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 442
SALN ATEIKDGLQCGTVSSQKQ ALKATTDEE SVSNIATEIKDGEKSGTVSSQK+PAL
Sbjct: 142 SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPAL 201
Query: 443 KATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTV 502
KAT+DEKDS SNI E KDGE S TVSSQKPPAL ATS +E SVL+IARE KDGEKSRTV
Sbjct: 202 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTV 261
Query: 503 SSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENK 562
S + P LKAT DEKDS NI RGKKDGE +R+VSS K P+LK TSD+EDSV +A E K
Sbjct: 262 SFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETK 321
Query: 563 DGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSF 622
D + S TVS +K P LKA+S +KDSV NI KDG+++ VSS+K+P+ +ATS +KDS
Sbjct: 322 DEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 381
Query: 623 SNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKA 682
SNI E KDG+I VSSQ+ PALK T DE+DSV IARE KDGEKS TVS +K K
Sbjct: 382 SNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKV 441
Query: 683 TSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSC 742
+K S+LNIA G K+ T LKA + +DSV N AT+ K+ Q S
Sbjct: 442 IFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQ 501
Query: 743 QKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDG 802
+ A + + + N QP K +D + +I +
Sbjct: 502 DLEMASEGEQKRLEEYEN-----------------NQPQVKNQIHSRDDLDDIIQSSQTV 544
Query: 803 QIRGTGILEYTFNV--MFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRIT 860
G + NV + DQ E K V K ++K+ + L +
Sbjct: 545 SEDGDSLCCNCKNVILLIDQHEMKCKDC-----VHLLKIKNTFCLWKRLIKLKD------ 593
Query: 861 GGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEM---------ASE 911
+ E L ++NK SVL K+ S + LE+ A +
Sbjct: 594 -------NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQ 646
Query: 912 GEQKRLEEYENNQPQVKNQIHSRDD-----------LDDIIQSSQTVSEDGDSLCCNCKN 960
E+K+ E +V+ ++ ++ + ++S++ + G N N
Sbjct: 647 QEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGG----NNSN 702
Query: 961 VILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIK--LKDNHCEQLRVK-IRKLKNKASVLQ 1017
+ D+ E D +H ++ RL K +K+ + E+ +K +K K LQ
Sbjct: 703 QVSETDEKE----DLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQ 758
Query: 1018 KRISEKEEIKSQ----LKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITE 1073
K + E ++ ++ L E +LR ++++++ R+ +E Q R +L
Sbjct: 759 KALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAA- 817
Query: 1074 EQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLE 1133
R + D + K + EL G T +K L EN I L+L
Sbjct: 818 ---RCDHDQSHSSK-----RDQELAFQG--------TVDKCRHLQENLNSHVLILSLQLS 861
Query: 1134 KDTIKNQNLEKKYLKDFEIVKRK---HEDLQKALKRNGETLAKTIACYSGQLAALTDENT 1190
K K++ L+ + E +K K E +Q LK+ + Y
Sbjct: 862 KAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGY-------N 914
Query: 1191 TLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQE 1250
T+ +EKQ C+L + Q + Q +D R+ +
Sbjct: 915 TMEKCIEKQER------------FCQL--------------KKQNMLLQQQLDDARNKAD 948
Query: 1251 NLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEK 1310
N +L + ++ +++ + L+ E ++ L+ E L + + K+ E
Sbjct: 949 NQEKAILNIQ---ARCDARVQNLQAE-------CRKHRLLLEEDNKMLVNELNHSKEKEC 998
Query: 1311 MYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQN 1370
Y+ EK ER +++ LQQ+ DD NK + KA+L+ +R ++N
Sbjct: 999 QYEK---------EKAEREVAVRQ----LQQKRDDVLNKG-SATKALLDASSRHCTYLEN 1044
Query: 1371 LQAECRKH----RLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLN 1426
+ RK R +E L + +KE E +K + E V +R++ +K+DD +
Sbjct: 1045 GMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVE-HVMMRKIIKKQDDQIE 1103
Query: 1427 K 1427
+
Sbjct: 1104 R 1104
Score = 387 bits (995), Expect = e-107
Identities = 246/475 (51%), Positives = 290/475 (61%), Gaps = 34/475 (7%)
Query: 229 EESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATE 288
E S ++ T + D S A K+ P G VSSQKQPAEKATSD+KDSVSNIATE
Sbjct: 22 ELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 81
Query: 289 IKEGPISGTVS----------------------------------SQKQPAEKATSDEKD 314
IKEG SGTVS SQKQPA K SD+ D
Sbjct: 82 IKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTD 141
Query: 315 SVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPAS 374
S N ATEIK G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQK+PA
Sbjct: 142 SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPAL 201
Query: 375 KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
KATSD+ DS NI E KDG TVSSQK PALKAT+ +EDSV NIA E KDGEKS TV
Sbjct: 202 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTV 261
Query: 435 SSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENK 494
S ++ P LKAT DEKDS+ NIA KDGEK+ VSS K P+L ATSD+E SV ++A E K
Sbjct: 262 SFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETK 321
Query: 495 DGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSV 554
D + S TVS +K+PALKATSD+KDS SNI KDG+ S VSSQK P K TS ++DSV
Sbjct: 322 DEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 381
Query: 555 LGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEA 614
IA E KDG+ TVSS++ P LK + EKDSV NIAR KDGEK+ VS +K+ + +
Sbjct: 382 SNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKV 441
Query: 615 TSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKS 669
+K S NI G S + LK T + +DSVL A + K+ + S
Sbjct: 442 IFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTS 496
Score = 360 bits (924), Expect = 6e-99
Identities = 230/470 (48%), Positives = 283/470 (60%), Gaps = 3/470 (0%)
Query: 179 NVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLS 238
N+ E K P +G VS ++ P T ++D +S + S S ++
Sbjct: 43 NIATEIKEGPISG---TVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQ 99
Query: 239 TLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTV 298
+ K+ A R G VSSQKQPA K SD DS N ATEIK+G GTV
Sbjct: 100 KVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTV 159
Query: 299 SSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIM 358
SSQKQ A KAT+DE+ SVSNIATEIK G++SGTVS QK+ A K +K S NI
Sbjct: 160 SSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKK 219
Query: 359 GGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSV 418
G S TVSSQK PA KATS K DS LNIA E KDG + TVS ++ P LKAT DE+DS+
Sbjct: 220 DGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSL 279
Query: 419 SNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTA 478
NIA KDGEK+ VSS KQP+LKAT+D++DSV N+ATE KD + SGTVS QK PAL A
Sbjct: 280 LNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKA 339
Query: 479 TSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSS 538
TSD++ SV +I E KDG++S TVSS+K+PA KATS +KDS SNI KDG+I VSS
Sbjct: 340 TSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSS 399
Query: 539 QKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDG 598
Q+ P LK T DE+DSV IARE KDGEKS TVS +K K +K S+LNIA G
Sbjct: 400 QRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGG 459
Query: 599 EKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKG 648
K+ +L+AT + KDS N + K+ + S A +G
Sbjct: 460 GKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEG 509
Score = 352 bits (904), Expect = 1e-96
Identities = 340/1092 (31%), Positives = 509/1092 (46%), Gaps = 96/1092 (8%)
Query: 170 ENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRD---HISTRFLGGMDSLT 226
E E +V + Q VSP++ K + +I+TR +GG S T
Sbjct: 65 EKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGT 124
Query: 227 SSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIA 286
S S++ P S + D + A KD G VSSQKQ A KAT+D++ SVSNIA
Sbjct: 125 VS---SQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIA 181
Query: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKK 346
TEIK+G SGTVSSQK+PA KATSDEKDS SNI E K G+ S TVS QK A K K
Sbjct: 182 TEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVK 241
Query: 347 KVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQP 406
+ S+LNIA G KS TVS ++ P KAT D+ DS LNIA KDG + VSS KQP
Sbjct: 242 EDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQP 301
Query: 407 ALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSG 466
+LKAT+D+EDSV N+ATE KD + SGTVS QKQPALKAT+D+KDSVSNI TEIKDG++SG
Sbjct: 302 SLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSG 361
Query: 467 TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRG 526
TVSSQK PA ATS ++ SV +IA E KDG+ TVSS+++PALK T DEKDS SNI R
Sbjct: 362 TVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIARE 421
Query: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKD 586
KDGE S VS QK K ++ S+L IA G KS T E LKA+ KD
Sbjct: 422 IKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKD 481
Query: 587 SVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646
SVLN A K+ + + + + E + + N + K+ SR +
Sbjct: 482 SVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSS 541
Query: 647 KGTSDEEDS---------VLGIARENKDGEKSRTVSSEKPPGL-KATSDEKDSVLNIARG 696
+ S++ DS +L E K + + + L K KD+ R
Sbjct: 542 QTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLR- 600
Query: 697 KKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKD 756
K R + + K I +KE+ + E + + C + A++ K+
Sbjct: 601 ----VKIRKLKNKASVLQKRISEKEEIKSQLKHEILELE---KELCSLRFAIQQEKKKRR 653
Query: 757 SVSNIPTEIKDGQQ--------SGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTG 808
+V + ++++ + V+ +PA K+ V+ + N + ++ + +
Sbjct: 654 NVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKED- 712
Query: 809 ILEYTFNVMFDQIE----EKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWK 864
L + +M D+I EK T N++ +K I K+K L A + G
Sbjct: 713 -LLHENRLMQDEIARLRLEKDTIKNQNL---EKKYLKDFEIVKRKHEDLQKALKRNG--- 765
Query: 865 SGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQ 924
TL TI + L T +T LE E Q+ E ++ +
Sbjct: 766 ---------ETLAKTIACYSGQLAALT-----DENTTLRSKLEKQRESRQRLETEMQSYR 811
Query: 925 PQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCC-----NCKNVILLIDQHEMKCKDCVHLL 979
++ N D + Q ++ G C N + +L++ K + +L
Sbjct: 812 CRL-NAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL 870
Query: 980 KIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEK 1039
K + + +K K E ++ ++++ +++ K I + + + +E ++
Sbjct: 871 KTELHYT--GEALKEKALVFEHVQSELKQKQSQ----MKDIEKMYKSGYNTMEKCIEKQE 924
Query: 1040 ELCSLR---FAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVE 1096
C L+ +QQ+ RN + +K I Q R +A V K +
Sbjct: 925 RFCQLKKQNMLLQQQLDDARNKADNQEKA-----ILNIQARCDARVQNLQAECRKHRLLL 979
Query: 1097 LKTGGNNSNQVSETDEKEDLLHENRLMQDEIA--RLRLEKDTIKNQNLEKKYLKD----- 1149
+ N+++ + EKE +E + E+A +L+ ++D + N+ K L D
Sbjct: 980 EEDNKMLVNELNHSKEKE-CQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRH 1038
Query: 1150 -------FEIVKRKHEDLQKALKRNGETLAKTIAC---YSGQLAALTDENTTLRSKLEKQ 1199
+ ++K + ++ + + L TI C G L E+ +R ++KQ
Sbjct: 1039 CTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQ 1098
Query: 1200 RESRQRLETEMQ 1211
+ +RLE +Q
Sbjct: 1099 DDQIERLEKILQ 1110
Score = 266 bits (681), Expect = 9e-71
Identities = 203/518 (39%), Positives = 265/518 (51%), Gaps = 31/518 (5%)
Query: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
VSSQKQPA K TSD+ DSVSN ATEIK+ Q+SGTV P + + ++ T
Sbjct: 57 VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 116
Query: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVD--RCLYLLDRFAQPV--TKDKFA 135
+S +S P K S ++ L E D +C + + Q + T D+
Sbjct: 117 MGGGKSGTVSSQKQPASKTASDKT-DSALNTATEIKDGLQCGTVSSQKQQALKATTDEEG 175
Query: 136 LESENISEPYFTNRR--TISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQK 193
S NI+ + T+S Q L A ++ + F + +K+ + T
Sbjct: 176 SVS-NIATEIKDGEKSGTVSSQKKPALKAT-----SDEKDSFSNITREKKDGEISRT--- 226
Query: 194 ANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAM 253
VS ++PP T D + D S S E+PP T E D A
Sbjct: 227 --VSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIAR 284
Query: 254 RRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEK 313
+KD +VSS KQP+ KATSD +DSV N+ATE K+ ISGTVS QKQPA KATSD+K
Sbjct: 285 GKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKK 344
Query: 314 DSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPA 373
DSVSNI TEIK GQQSGTVS QKQ AWK KK S+ NIAT I G GTVSSQ++PA
Sbjct: 345 DSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPA 404
Query: 374 SKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGT 433
K T D+ DS NIA EIKDG + GTVS QKQ A K ++ S+ NIAT I G KSGT
Sbjct: 405 LKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGT 464
Query: 434 VSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIAREN 493
+ LKAT + KDSV N AT++K+ + T+T E+ ++ E
Sbjct: 465 EYPENLRTLKATIENKDSVLNTATKMKEVQ-------------TSTPAEQDLEMASEGEQ 511
Query: 494 KDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGE 531
K E+ + K + + D D + +DG+
Sbjct: 512 KRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGD 549
Score = 228 bits (582), Expect = 3e-59
Identities = 170/414 (41%), Positives = 213/414 (51%), Gaps = 31/414 (7%)
Query: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQC 61
V +L A + S VSSQKQPA K SDK DS NTATEIKD + GTV +Q
Sbjct: 107 VSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQA 166
Query: 62 LNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPV-EEAVDRCLY 120
L + +V+ TE + +S +S P K S KD + E D
Sbjct: 167 LKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDE--KDSFSNITREKKD---- 220
Query: 121 LLDRFAQPVTKDK-FALESENISEPYFTN----------RRTISQQSAENLDAACGIDKT 169
++ V+ K AL++ ++ E N RT+S + L A +
Sbjct: 221 --GEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKAT----RD 274
Query: 170 ENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSE 229
E ++ K+G+ + VS + P T D + D S
Sbjct: 275 EKDSLLNIARGKKDGE------KTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGT 328
Query: 230 ESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEI 289
S ++ P T + D S KD G VSSQKQPA KATS KDSVSNIATEI
Sbjct: 329 VSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEI 388
Query: 290 KEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVS 349
K+G I GTVSSQ++PA K T DEKDSVSNIA EIK G++SGTVSPQKQSA KVIFKKKVS
Sbjct: 389 KDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVS 448
Query: 350 LLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQ 403
LLNIATRI GGGKSGT + KAT + DS LN AT++K+ +Q T + Q
Sbjct: 449 LLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKE-VQTSTPAEQ 501
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 1541 bits (3991), Expect = 0.0
Identities = 802/862 (93%), Positives = 815/862 (94%), Gaps = 8/862 (0%)
Query: 671 TVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATE 730
+VSSEKP GLKATSDEKDSVLNIARGKK GEKTR VSS KQPALKA DKE+SVPNMATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 731 KKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 790
KDEQISGTVS QKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 791 SVSNIATEIKDGQIRGT------GILEYTFNVM--FDQIEEKFTSLNKSAGVSPQKQSAQ 842
SVSNIATEIKDGQIRGT L+ T + I + KS VSPQKQSAQ
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 843 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 902
KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
Query: 903 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 962
EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 306
Query: 963 LLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISE 1022
LLIDQHEMKCKDCVHLLKIK TFCL KRL +LKDNHCEQLRVKIRKLKNKASVLQKR+SE
Sbjct: 307 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE 366
Query: 1023 KEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADV 1082
KEEIKSQLKHE LELEKELCSLRFAIQQEKKKRRNVEE+HQKVREKLRITEEQYRIEADV
Sbjct: 367 KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 426
Query: 1083 TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL 1142
TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL
Sbjct: 427 TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL 486
Query: 1143 EKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRES 1202
EKKYLKDFEIVKRKHEDLQKALKRN ETLA+TIACYSGQLAALTDENTTLRSKLEKQRES
Sbjct: 487 EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRES 546
Query: 1203 RQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQ 1262
QRLETEMQSY CRLNAA CDHDQSHSSKRDQELAFQGTVDKC HLQENLNSHVLILSLQ
Sbjct: 547 GQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQ 606
Query: 1263 LSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 1322
LSKAESK RVL+TELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC
Sbjct: 607 LSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 666
Query: 1323 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLL 1382
IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARV+NLQAECRKHRLLL
Sbjct: 667 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 726
Query: 1383 EEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC 1442
EEDNKMLVNEL HSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC
Sbjct: 727 EEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC 786
Query: 1443 TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQD 1502
TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGD QKLEVE+VMMRKIIKKQD
Sbjct: 787 TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQD 846
Query: 1503 DQIERLEKILQHSSLMLQVFES 1524
+QIER EKILQHSSLMLQVFES
Sbjct: 847 EQIERFEKILQHSSLMLQVFES 868
Score = 248 bits (634), Expect = 2e-65
Identities = 258/900 (28%), Positives = 412/900 (45%), Gaps = 102/900 (11%)
Query: 365 TVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 424
+VSS+K KATSD+ DS LNIA K G + VSS KQPALKAT+D+E+SV N+ATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 425 IKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEG 484
KD + SGTVSSQKQPALKAT+D+KDSVSNI TEIKDG++SGTVSSQK PA ATS ++
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 485 SVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 544
SV +IA E KDG+ TVSS+++PALKAT DEKDS SNI R KDGE S VS QK
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 545 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRV 604
K ++ S+L IA G KS T E P LKA+ K+SVLN A KD + +
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
Query: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDS--------- 655
+ + E + + N + K+ SR + + S++ DS
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 306
Query: 656 VLGIARENKDGEKSRTVSSEKPPGL-KATSDEKDSVLNIARGKKDGEKTRTVSSPKQPAL 714
+L E K + + +K L K ++ KD+ R K R + +
Sbjct: 307 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLR-----VKIRKLKNKASVLQ 361
Query: 715 KAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQ---- 770
K + +KE+ + E + + C + A++ K+ +V + ++++ +
Sbjct: 362 KRLSEKEEIKSQLKHETLELE---KELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEE 418
Query: 771 ----SGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIE---- 822
V+ +PA K+ V+ + N + ++ + + L + +M D+I
Sbjct: 419 QYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKED--LLHENRLMQDEIARLRL 476
Query: 823 EKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIEN 882
EK T N++ +K I K+K L A + N TL TI
Sbjct: 477 EKDTIKNQNL---EKKYLKDFEIVKRKHEDLQKALK------------RNEETLAETIAC 521
Query: 883 KNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQ 942
+ L T +T LE E Q+ E ++ + ++ + D +
Sbjct: 522 YSGQLAALT-----DENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKR 576
Query: 943 SSQTVSEDGDSLCC----NCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNH 998
+ + CC N + +L++ + L K ++ F R+++ + ++
Sbjct: 577 DQELAFQGTVDKCCHLQENLNSHVLILS---------LQLSKAESKF----RVLETELHY 623
Query: 999 C-EQLRVKIRKLKNKASVLQKRISEKEEIKSQLK------HEILELEKELCSLR---FAI 1048
E L+ K ++ S L+++ S+ ++I+ K + +E ++ C L+ +
Sbjct: 624 TGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLL 683
Query: 1049 QQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVS 1108
QQ+ RN + +K I Q R +A V K + + N+++
Sbjct: 684 QQQLDDARNKADNQEKA-----ILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELT 738
Query: 1109 ETDEKEDLLHENRLMQDEIA--RLRLEKDTIKNQNLEKKYLKD------------FEIVK 1154
+ EKE +E + E+A +L+ ++D + N+ K L D + +
Sbjct: 739 HSKEKE-CQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSR 797
Query: 1155 RKHEDLQKALKRNGETLAKTIAC---YSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 1211
+K + ++ + + L TI C G L EN +R ++KQ E +R E +Q
Sbjct: 798 KKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQ 857
Score = 246 bits (627), Expect = 2e-64
Identities = 255/887 (28%), Positives = 397/887 (44%), Gaps = 104/887 (11%)
Query: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
VSS+K KATSD+KDSV NIA K G + VSS KQPA KATSD+++SV N+ATE
Sbjct: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
Query: 324 KKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDS 383
K Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQPA KATS K DS
Sbjct: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
Query: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
NIATEIKDG GTVSSQ+QPALKAT DE+DSVSNIA EIKDGEKSGTVS QKQ A K
Sbjct: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187
Query: 444 ATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVS 503
+K S+ NIAT I G KSGT + P L AT + + SVL+ A + KD + S
Sbjct: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 247
Query: 504 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDS--------VL 555
+ A + + + N K+ SR + + S++ DS +L
Sbjct: 248 QDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVIL 307
Query: 556 GIARENKDGE--------KSRTVSSEKPPGLKASSAE-----------KDSVLNIARGKK 596
I + + K ++ LK + E K SVL K+
Sbjct: 308 LIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ----KR 363
Query: 597 DGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 656
EK + S K +LE + I +EKK ++ + L+ T ++
Sbjct: 364 LSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIE 423
Query: 657 LGIARENKDGEKSRTV---SSEKPPGLKATSDEKDSVLN--------IARGK--KDGEKT 703
+ + K KS V + + +DEK+ +L+ IAR + KD K
Sbjct: 424 ADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKN 483
Query: 704 RTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSD---------- 753
+ + + + K + + A ++ +E ++ T++C T +
Sbjct: 484 QNLEKKYLKDFEIVKRKHEDL-QKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEK 542
Query: 754 KKDSVSNIPTEIK-----------DGQQSGTVSSQKQPAWKATSVK--------KDSVSN 794
+++S + TE++ D QS + ++ A++ T K V
Sbjct: 543 QRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLI 602
Query: 795 IATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLN 854
++ ++ + + +LE + + ++EK QKQS K I K S N
Sbjct: 603 LSLQLSKAESK-FRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYN 661
Query: 855 IATRITGGWKSGTEYPENLPTLKATIEN-KNSVLNTATKMKDVQTSTPAEQDLEMASEGE 913
+ + + + L+ +++ +N N + ++Q A + + +E
Sbjct: 662 TMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVE-NLQAECR 720
Query: 914 QKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCK 973
+ RL E+N+ V HS++ + Q E + + + Q + K
Sbjct: 721 KHRLLLEEDNKMLVNELTHSKE------KECQYEKEKAER--------EVAVRQLQQKRD 766
Query: 974 DCVHLLKIKNTFCLWKRLIKLKDNHCEQL-------RVKIRKLKNKASVLQKRISEKEEI 1026
D + N K L+ HC L R K+ +++++ +Q +++
Sbjct: 767 D------VLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRC 820
Query: 1027 KSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITE 1073
+++ + +LE E +R I+++ ++ E++ Q L++ E
Sbjct: 821 TKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVFE 867
Score = 235 bits (600), Expect = 2e-61
Identities = 142/241 (58%), Positives = 162/241 (67%)
Query: 293 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLN 352
P +VSS+K KATSDEKDSV NIA K G+++ VS KQ A K K+ S+ N
Sbjct: 3 PFYFSVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPN 62
Query: 353 IATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 412
+AT SGTVSSQKQPA KATSDK DS NI TEIKDG Q GTVSSQKQPA KAT+
Sbjct: 63 MATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATS 122
Query: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQK 472
++DSVSNIATEIKDG+ GTVSSQ+QPALKAT DEKDSVSNIA EIKDGEKSGTVS QK
Sbjct: 123 VKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 182
Query: 473 PPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEI 532
A ++ S+L+IA G KS T P LKAT + K+S N KD +
Sbjct: 183 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 242
Query: 533 S 533
S
Sbjct: 243 S 243
Score = 71.2 bits (173), Expect = 7e-12
Identities = 51/138 (36%), Positives = 64/138 (46%)
Query: 192 QKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKA 251
Q VS ++ P + T +D +S D SS+R P T E D S
Sbjct: 106 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNI 165
Query: 252 AMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSD 311
A KD G VS QKQ A+K K S+ NIAT I G SGT + P KAT +
Sbjct: 166 AREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIE 225
Query: 312 EKDSVSNIATEIKKGQQS 329
K+SV N AT++K Q S
Sbjct: 226 NKNSVLNTATKMKDVQTS 243
Score = 61.6 bits (148), Expect = 6e-09
Identities = 82/306 (26%), Positives = 117/306 (38%), Gaps = 76/306 (24%)
Query: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
VSS KQPALK TSDK++SV N ATE KDEQ SGTV + L + + D+V+ TE
Sbjct: 42 VSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEI 101
Query: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139
+ +S +S P K A V KD + +
Sbjct: 102 KDGQQSGTVSSQKQPAWK----------------------------ATSVKKDSVSNIAT 133
Query: 140 NISEPYFTNRRTISQQSAENLDAACGIDKTENGNMF-EDQNVDKEGKALPATGQKANVSP 198
I + R T+S Q L A G +K N+ E ++ +K G P QK +
Sbjct: 134 EIKDGQI--RGTVSSQRQPALKAT-GDEKDSVSNIAREIKDGEKSGTVSP---QKQSA-- 185
Query: 199 EQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDS 258
Q +F V +I+TR GG S T E+
Sbjct: 186 -QKVIFKKKV-SLLNIATRITGGWKSGTEYPEN--------------------------- 216
Query: 259 PPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 318
P KAT ++K+SV N AT++K+ S + A + + N
Sbjct: 217 ----------LPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYEN 266
Query: 319 IATEIK 324
++K
Sbjct: 267 NQPQVK 272
Score = 61.2 bits (147), Expect = 7e-09
Identities = 36/71 (50%), Positives = 42/71 (59%)
Query: 8 AASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLY 67
A E S VSSQKQPALK TSDK DSVSN TEIKD Q+SGTV + +
Sbjct: 64 ATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV 123
Query: 68 RPDAVAQPVTE 78
+ D+V+ TE
Sbjct: 124 KKDSVSNIATE 134
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 1490 bits (3857), Expect = 0.0
Identities = 810/938 (86%), Positives = 829/938 (88%), Gaps = 49/938 (5%)
Query: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ
Sbjct: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
Query: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY
Sbjct: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
Query: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV
Sbjct: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
Query: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL
Sbjct: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
Query: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS
Sbjct: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
Query: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGG 360
QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSA KVIFKKKVSLLNIATRIMGG
Sbjct: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGG 360
Query: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN
Sbjct: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
Query: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS
Sbjct: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
Query: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
DEEGSVLSIARENKDGEKSRTVSSRKKPA KATSDEKDSFSNITRGKKDGEISRKVSSQK
Sbjct: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
Query: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEK 600
PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASS EKDSVLNIARGKK GEK
Sbjct: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEK 600
Query: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA
Sbjct: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
Query: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDK 720
RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSS K P LKA D+
Sbjct: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDE 720
Query: 721 EDSVPNMATEKKDEQISGTVSCQ----------------------------------KQP 746
EDSV ++A E KD + S TVS + K+P
Sbjct: 721 EDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKP 780
Query: 747 ALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRG 806
ALKATSD+KDSV I E KDG++S TVSSQKQPA KA K+DSV N+ATE KD QI G
Sbjct: 781 ALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISG 840
Query: 807 T------GILEYTFNV--MFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATR 858
T L+ T + I + +S VSPQKQSAQKVIFKKKVSLLNIATR
Sbjct: 841 TVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSPQKQSAQKVIFKKKVSLLNIATR 900
Query: 859 ITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDV 896
ITGGWKSGT ++ IE+ + T K DV
Sbjct: 901 ITGGWKSGT-------VIRQAIEHDECLCYTGIKPSDV 931
Score = 317 bits (812), Expect = 6e-86
Identities = 247/655 (37%), Positives = 328/655 (50%), Gaps = 48/655 (7%)
Query: 348 VSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPA 407
V +L A + S VSSQKQPA K TSDK DS N ATEIKD + GTV +
Sbjct: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQC 61
Query: 408 LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEK------------------ 449
L + D+V+ TE + +S +S P K +
Sbjct: 62 LNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYL 121
Query: 450 -DSVSNIATEIKDGEKSG-----------TVSSQKPPALTAT----SDEEGSVLSIAREN 493
D + T+ K +S T+S Q L A E G++ +
Sbjct: 122 LDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVD 181
Query: 494 KDGE------KSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGT 547
K+G+ + VS + P T ++D S G D S + SS++PP T
Sbjct: 182 KEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLT 241
Query: 548 SDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSR 607
E D A KD VSS+K P KA+S +KDSV NIA K+G + VSS+
Sbjct: 242 LKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQ 301
Query: 608 KKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGE 667
K+P+ +ATSDEKDS SNI E K G+ S VS QK A K ++ S+L IA G
Sbjct: 302 KQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGG 361
Query: 668 KSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNM 727
KS TVSS+K P KATSD+ DS LNIA KDG + TVSS KQPALKA D+EDSV N+
Sbjct: 362 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 421
Query: 728 ATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV 787
ATE KD + SGTVS QKQPALKAT+D+KDSVSNI TEIKDG++SGTVSSQK PA ATS
Sbjct: 422 ATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSD 481
Query: 788 KKDSVSNIATEIKDGQ-IRGTGILEYTFNVMFDQIEEKFTSLNK-------SAGVSPQKQ 839
++ SV +IA E KDG+ R + + ++ F+++ + S VS QK
Sbjct: 482 EEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKP 541
Query: 840 SAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 899
K ++ S+L IA G KS T E P LKA+ + K+SVLN A K + +
Sbjct: 542 PTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKT 601
Query: 900 TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 954
+ + E + + N + K+ SR + + S++ DS+
Sbjct: 602 KRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 656
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 921 bits (2381), Expect = 0.0
Identities = 516/638 (80%), Positives = 522/638 (81%), Gaps = 94/638 (14%)
Query: 298 VSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI 357
+S QKQPAEKATSDEKDSVSNIATEIK+GQQSGTVSPQKQSA KVIFKKKVSLLNIATRI
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 358 MGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 417
MGGGKSGTVSSQKQPASK SDKTDSALN ATEIKDGLQCGTVSSQKQ ALKATTDEE S
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 418 VSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALT 477
VSNIATEIKDGEKSGTVSSQK+PALKAT+DEKDS SNI E KDGE S TVSSQKPPAL
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 478 ATSDEEGSVLSIARENKDGEKSRTVS---------------------------------- 503
ATS +E SVL+IARE KDGEKSRTVS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 504 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 563
SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 564 GEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFS 623
GEKSRTVSSEKPPGLKASS EKDSVLNIARGKK GEKTKRVSSRKKPSLEATSDEKDSFS
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 624 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 683
NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
Query: 684 SDEKDSVLNIARGKKDGEKT----------------------------------RTVSSP 709
SDEKDSVLNIARGKKDGEKT RTVSS
Sbjct: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
Query: 710 KQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQ 769
KQPALKAICDKEDSVPNMATEKKDEQISGTVS QKQPALKATSDKKDSVSNIPTEIKDGQ
Sbjct: 572 KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 631
Query: 770 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLN 829
QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGT
Sbjct: 632 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGT---------------------- 669
Query: 830 KSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGT 867
VSPQKQSAQKVIFKKKVSLLNIATRITGG KSGT
Sbjct: 670 ----VSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGT 703
Score = 631 bits (1628), Expect = e-180
Identities = 363/574 (63%), Positives = 420/574 (73%), Gaps = 12/574 (2%)
Query: 366 VSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEI 425
+S QKQPA KATSD+ DS NIATEIK+G Q GTVS QKQ A K ++ S+ NIAT I
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 426 KDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGS 485
G KSGTVSSQKQPA K +D+ DS N ATEIKDG + GTVSSQK AL AT+DEEGS
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 486 VLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLK 545
V +IA E KDGEKS TVSS+KKPALKATSDEKDSFSNITR KKDGEISR VSSQKPP LK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 546 GTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVS 605
TS +EDSVL IARE KDGEKSRTVS ++PPGLKA+ EKDS+LNIARGKK+GEKT+RVS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 606 SRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKD 665
SRKKP+L+ATSDEKDSFSNITR KKDGEISRKVSSQKPP LKGTSDEEDSVLGIARENKD
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 666 GEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVP 725
GEKSRTVSSEKPPGLKA+SDEKDSVLNIARGKK GEKT+ VSS K+P+L+A D++DS
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 726 NMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKAT 785
N+ EKKD +IS VS QK PALK TSD++DSV I E KDG++S TVSS+K P KAT
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
Query: 786 SVKKDSVSNIATEIKDGQIRGT----------GILEYTFNVMFDQIEEKFTSLNKSAGVS 835
S +KDSV NIA KDG+ T + +V++ E+K KS VS
Sbjct: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKK--DGEKSRTVS 569
Query: 836 PQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKD 895
QKQ A K I K+ S+ N+AT SGT + P LKAT + K+SV N T++KD
Sbjct: 570 SQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKD 629
Query: 896 VQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKN 929
Q S + A + + + N ++K+
Sbjct: 630 GQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKD 663
Score = 462 bits (1189), Expect = e-129
Identities = 307/607 (50%), Positives = 355/607 (58%), Gaps = 74/607 (12%)
Query: 170 ENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRD---HISTRFLGGMDSLT 226
E E +V + Q VSP++ K + +I+TR +GG S T
Sbjct: 100 EKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGT 159
Query: 227 SSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIA 286
S S++ P S + D + A KD G VSSQKQ A KAT+D++ SVSNIA
Sbjct: 160 VS---SQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIA 216
Query: 287 TEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKK 346
TEIK+G SGTVSSQK+PA KATSDEKDS SNI E K G+ S TVS QK A K K
Sbjct: 217 TEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVK 276
Query: 347 ----------------------------------KVSLLNIATRIMGGGKSGTVSSQKQP 372
K SLLNIA G K+ VSS+K+P
Sbjct: 277 EDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKKP 336
Query: 373 ASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSG 432
A KATSD+ DS NI KDG VSSQK P LK T+DEEDSV IA E KDGEKS
Sbjct: 337 ALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSR 396
Query: 433 TVSSQKQPALKATTDEKDSV----------------------------------SNIATE 458
TVSS+K P LKA++DEKDSV SNI E
Sbjct: 397 TVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 456
Query: 459 IKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKD 518
KDGE S VSSQKPPAL TSDEE SVL IARENKDGEKSRTVSS K P LKATSDEKD
Sbjct: 457 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 516
Query: 519 SFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 578
S NI RGKKDGE +R VSS+K P LK TSDE+DSVL IARE KDGEKSRTVSS+K P L
Sbjct: 517 SVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPAL 576
Query: 579 KASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKV 638
KA ++DSV N+A KKD + + VSS+K+P+L+ATSD+KDS SNI E KDG+ S V
Sbjct: 577 KAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTV 636
Query: 639 SSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKK 698
SSQK PA K TS ++DSV IA E KDG+ TVS +K K +K S+LNIA
Sbjct: 637 SSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRIT 696
Query: 699 DGEKTRT 705
G K+ T
Sbjct: 697 GGGKSGT 703
Score = 436 bits (1121), Expect = e-122
Identities = 300/677 (44%), Positives = 378/677 (55%), Gaps = 46/677 (6%)
Query: 1 MVQILKNAASVFSETT------SLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTV 54
++ +L++ VFS +S QKQPA K TSD+ DSVSN ATEIK+ Q+SGTV
Sbjct: 67 VILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTV 126
Query: 55 LPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEA 114
P + + ++ T +S +S P K S ++
Sbjct: 127 SPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKT----------- 175
Query: 115 VDRCLYLLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNM 174
D T+ K L+ T+S Q + L A E G++
Sbjct: 176 --------DSALNTATEIKDGLQC-----------GTVSSQKQQALKAT----TDEEGSV 212
Query: 175 FEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSER 234
K+G+ + VS ++ P T ++D S D S SS++
Sbjct: 213 SNIATEIKDGE------KSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 266
Query: 235 PPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPI 294
PP T + D A +KD VS + P KAT D+KDS+ NIA K G
Sbjct: 267 PPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEK 326
Query: 295 SGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIA 354
+ VSS+K+PA KATSDEKDS SNI K G+ S VS QK K ++ S+L IA
Sbjct: 327 TRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 386
Query: 355 TRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDE 414
G KS TVSS+K P KA+SD+ DS LNIA K G + VSS+K+P+L+AT+DE
Sbjct: 387 RENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDE 446
Query: 415 EDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPP 474
+DS SNI E KDGE S VSSQK PALK T+DE+DSV IA E KDGEKS TVSS+KPP
Sbjct: 447 KDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 506
Query: 475 ALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISR 534
L ATSDE+ SVL+IAR KDGEK+RTVSSRKKPALKATSDEKDS I R KKDGE SR
Sbjct: 507 GLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSR 566
Query: 535 KVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARG 594
VSSQK P LK D+EDSV +A E KD + S TVSS+K P LKA+S +KDSV NI
Sbjct: 567 TVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTE 626
Query: 595 KKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEED 654
KDG+++ VSS+K+P+ +ATS +KDS SNI E KDG+I VS QK A K ++
Sbjct: 627 IKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKV 686
Query: 655 SVLGIARENKDGEKSRT 671
S+L IA G KS T
Sbjct: 687 SLLNIATRITGGGKSGT 703
Score = 374 bits (961), Expect = e-103
Identities = 252/543 (46%), Positives = 313/543 (57%), Gaps = 63/543 (11%)
Query: 468 VSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGK 527
+S QK PA ATSDE+ SV +IA E K+G++S TVS +K+ A K +K S NI
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 528 KDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDS 587
G S VSSQK P K SD+ DS L A E KDG + TVSS+K LKA++ E+ S
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 588 VLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALK 647
V NIA KDGEK+ VSS+KKP+L+ATSDEKDSFSNITREKKDGEISR VSSQKPPALK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 648 GTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVS 707
TS +EDSVL IARE KDGEKSRTVS ++PPGLKAT DEKDS+LNIARGKK+GEKTR VS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 708 SPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKD 767
S K+PALKA D++DS N+ KKD +IS VS QK P LK TSD++DSV I E KD
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 768 GQQSGTVSSQKQPAWKATSVKKDSV----------------------------------S 793
G++S TVSS+K P KA+S +KDSV S
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 794 NIATEIKDGQIRGT----------GILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQK 843
NI E KDG+I G + +V+ E K KS VS +K K
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENK--DGEKSRTVSSEKPPGLK 509
Query: 844 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 903
+K S+LNIA G K+ T P LKAT + K+SVL A + KD + S
Sbjct: 510 ATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVS 569
Query: 904 QDLE---------------MASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVS 948
+ MA+E + +++ ++Q Q + + D D + + T
Sbjct: 570 SQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQ--PALKATSDKKDSVSNIPTEI 627
Query: 949 EDG 951
+DG
Sbjct: 628 KDG 630
Score = 272 bits (695), Expect = 2e-72
Identities = 200/498 (40%), Positives = 259/498 (52%), Gaps = 39/498 (7%)
Query: 468 VSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDS-------- 519
+ ++ P L A S + ++ + K + R L T EKD
Sbjct: 15 ILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHN 74
Query: 520 ---FSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 576
FS GK + + +S QK P K TSDE+DSV IA E K+G++S TVS +K
Sbjct: 75 IDVFSRDVYGKLAEDYA--MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQS 132
Query: 577 GLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISR 636
K +K S+LNIA G K+ VSS+K+P+ + SD+ DS N E KDG
Sbjct: 133 AQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCG 192
Query: 637 KVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARG 696
VSSQK ALK T+DEE SV IA E KDGEKS TVSS+K P LKATSDEKDS NI R
Sbjct: 193 TVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITRE 252
Query: 697 KKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKD 756
KKDGE +RTVSS K PALKA KEDSV N+A EKKD + S TVS + P LKAT D+KD
Sbjct: 253 KKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKD 312
Query: 757 SVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNV 816
S+ NI K+G+++ VSS+K+PA KATS +KDS SNI KDG+I
Sbjct: 313 SLLNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEI------------ 360
Query: 817 MFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTL 876
S VS QK K ++ S+L IA G KS T E P L
Sbjct: 361 --------------SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 406
Query: 877 KATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDD 936
KA+ + K+SVLN A K + + + + E + + N + K+ SR
Sbjct: 407 KASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKV 466
Query: 937 LDDIIQSSQTVSEDGDSL 954
+ + S++ DS+
Sbjct: 467 SSQKPPALKGTSDEEDSV 484
>gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 475
Score = 863 bits (2231), Expect = 0.0
Identities = 436/443 (98%), Positives = 442/443 (99%)
Query: 974 DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 1033
DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE
Sbjct: 24 DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 83
Query: 1034 ILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSA 1093
ILELEKELCSLRFAIQQEKKKRRNVEE+HQKVREKLRITEEQYRIEADVTKPIKPALKSA
Sbjct: 84 ILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA 143
Query: 1094 EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIV 1153
EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRL+ DTIKNQNLEKKYLKDFEIV
Sbjct: 144 EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLDTDTIKNQNLEKKYLKDFEIV 203
Query: 1154 KRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY 1213
KRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY
Sbjct: 204 KRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY 263
Query: 1214 HCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL 1273
HCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL
Sbjct: 264 HCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL 323
Query: 1274 KTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK 1333
KTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK
Sbjct: 324 KTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK 383
Query: 1334 KQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNEL 1393
KQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNEL
Sbjct: 384 KQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNEL 443
Query: 1394 NHSKEKECQYEKEKAEREVAVRQ 1416
NHSKEKECQYEKEKAEREV++++
Sbjct: 444 NHSKEKECQYEKEKAEREVSIKK 466
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 613 bits (1581), Expect = e-175
Identities = 329/384 (85%), Positives = 347/384 (90%)
Query: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI
Sbjct: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
Query: 324 KKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDS 383
K+GQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI GGGKSGTVSSQKQPASKATSDKTDS
Sbjct: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
Query: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK
Sbjct: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
Query: 444 ATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVS 503
ATTDE+DSV NIATEIKDGEKS TVSSQK PAL AT+DEE SV IA E KDGEKS TVS
Sbjct: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
Query: 504 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 563
SRKKPALKATSDEKDSFSNITR KKDGEISR V+S+KP LK TSDEEDSVL IAR +D
Sbjct: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKED 307
Query: 564 GEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFS 623
GEK+R VSS K P LKA+S EKDS NI R KKDGE ++ VSS+K P+L+ATSDE+DS
Sbjct: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL 367
Query: 624 NITREKKDGEISRKVSSQKPPALK 647
+I RE+KDGE SR VSS++PP LK
Sbjct: 368 SIAREEKDGEKSRTVSSEQPPGLK 391
Score = 527 bits (1357), Expect = e-149
Identities = 292/389 (75%), Positives = 319/389 (82%)
Query: 293 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLN 352
P +VSSQKQPAEKATSD+KDSVSNIATEIK+G SGTVS QKQ A K +K S+ N
Sbjct: 3 PFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 62
Query: 353 IATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 412
IAT I G +SGTVS QKQ A K K S LNIAT I G + GTVSSQKQPA KAT+
Sbjct: 63 IATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATS 122
Query: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQK 472
D+ DS NIATEIKDG + GTVSSQKQPALKATTDE+DSVSNIATEIKDGEKSGTVSSQK
Sbjct: 123 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 182
Query: 473 PPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEI 532
PAL AT+DEE SVL+IA E KDGEKS TVSS+K+PALKAT+DE+DS S I KDGE
Sbjct: 183 QPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK 242
Query: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIA 592
S VSS+K P LK TSDE+DS I RE KDGE SRTV+SEKP GLKA+S E+DSVLNIA
Sbjct: 243 SGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIA 302
Query: 593 RGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDE 652
RGK+DGEKT+RVSSRKKP+L+ATSDEKDSFSNITREKKDGE SR VSSQKPPALK TSDE
Sbjct: 303 RGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDE 362
Query: 653 EDSVLGIARENKDGEKSRTVSSEKPPGLK 681
EDSVL IARE KDGEKSRTVSSE+PPGLK
Sbjct: 363 EDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
Score = 468 bits (1205), Expect = e-131
Identities = 263/385 (68%), Positives = 299/385 (77%)
Query: 365 TVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 424
+VSSQKQPA KATSD DS NIATEIK+G GTVSSQKQPA KAT+DE+DSVSNIATE
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 425 IKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEG 484
IK+G++SGTVS QKQ A K +K S+ NIAT I G KSGTVSSQK PA ATSD+
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 485 SVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL 544
S L+IA E KDG + TVSS+K+PALKAT+DE+DS SNI KDGE S VSSQK P L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 545 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRV 604
K T+DEEDSVL IA E KDGEKS TVSS+K P LKA++ E+DSV IA KDGEK+ V
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 605 SSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENK 664
SSRKKP+L+ATSDEKDSFSNITREKKDGEISR V+S+KP LK TSDEEDSVL IAR +
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 665 DGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSV 724
DGEK+R VSS K P LKATSDEKDS NI R KKDGE +RTVSS K PALKA D+EDSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 725 PNMATEKKDEQISGTVSCQKQPALK 749
++A E+KD + S TVS ++ P LK
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391
Score = 454 bits (1167), Expect = e-127
Identities = 260/383 (67%), Positives = 281/383 (73%), Gaps = 34/383 (8%)
Query: 231 SSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIK 290
SS++ P T + D S A K+ P G VSSQKQPAEKATSD+KDSVSNIATEIK
Sbjct: 9 SSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 68
Query: 291 EGPISGTVS----------------------------------SQKQPAEKATSDEKDSV 316
EG SGTVS SQKQPA KATSD+ DS
Sbjct: 69 EGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSA 128
Query: 317 SNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKA 376
NIATEIK G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQKQPA KA
Sbjct: 129 LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKA 188
Query: 377 TSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSS 436
T+D+ DS LNIATEIKDG + TVSSQKQPALKATTDEEDSVS IATEIKDGEKSGTVSS
Sbjct: 189 TTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSS 248
Query: 437 QKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDG 496
+K+PALKAT+DEKDS SNI E KDGE S TV+S+KP L ATSDEE SVL+IAR +DG
Sbjct: 249 RKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDG 308
Query: 497 EKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLG 556
EK+R VSSRKKPALKATSDEKDSFSNITR KKDGE SR VSSQKPP LK TSDEEDSVL
Sbjct: 309 EKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLS 368
Query: 557 IARENKDGEKSRTVSSEKPPGLK 579
IARE KDGEKSRTVSSE+PPGLK
Sbjct: 369 IAREEKDGEKSRTVSSEQPPGLK 391
Score = 398 bits (1023), Expect = e-110
Identities = 233/385 (60%), Positives = 274/385 (71%), Gaps = 34/385 (8%)
Query: 433 TVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARE 492
+VSSQKQPA KAT+D+KDSVSNIATEIK+G SGTVSSQK PA ATSDE+ SV +IA E
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 493 NKDGE----------------------------------KSRTVSSRKKPALKATSDEKD 518
K+G+ KS TVSS+K+PA KATSD+ D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 519 SFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGL 578
S NI KDG VSSQK P LK T+DEEDSV IA E KDGEKS TVSS+K P L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 579 KASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKV 638
KA++ E+DSVLNIA KDGEK++ VSS+K+P+L+AT+DE+DS S I E KDGE S V
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 639 SSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKK 698
SS+K PALK TSDE+DS I RE KDGE SRTV+SEKP GLKATSDE+DSVLNIARGK+
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 699 DGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSV 758
DGEKTR VSS K+PALKA D++DS N+ EKKD + S TVS QK PALKATSD++DSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 759 SNIPTEIKDGQQSGTVSSQKQPAWK 783
+I E KDG++S TVSS++ P K
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391
Score = 344 bits (883), Expect = 3e-94
Identities = 210/371 (56%), Positives = 250/371 (67%), Gaps = 34/371 (9%)
Query: 467 TVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNIT-- 524
+VSSQK PA ATSD++ SV +IA E K+G S TVSS+K+PA KATSDEKDS SNI
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 525 --RGKKDGEISRK------------------------------VSSQKPPTLKGTSDEED 552
G++ G +S + VSSQK P K TSD+ D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 553 SVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSL 612
S L IA E KDG + TVSS+K P LKA++ E+DSV NIA KDGEK+ VSS+K+P+L
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 613 EATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTV 672
+AT+DE+DS NI E KDGE S VSSQK PALK T+DEEDSV IA E KDGEKS TV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 673 SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKK 732
SS K P LKATSDEKDS NI R KKDGE +RTV+S K LKA D+EDSV N+A K+
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 733 DEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 792
D + + VS +K+PALKATSD+KDS SNI E KDG+ S TVSSQK PA KATS ++DSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 793 SNIATEIKDGQ 803
+IA E KDG+
Sbjct: 367 LSIAREEKDGE 377
Score = 298 bits (763), Expect = 3e-80
Identities = 192/373 (51%), Positives = 237/373 (63%), Gaps = 10/373 (2%)
Query: 536 VSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGK 595
VSSQK P K TSD++DSV IA E K+G S TVSS+K P KA+S EKDSV NIA
Sbjct: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
Query: 596 KDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDS 655
K+G+++ VS +K+ + + +K S NI G S VSSQK PA K TSD+ DS
Sbjct: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
Query: 656 VLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALK 715
L IA E KDG + TVSS+K P LKAT+DE+DSV NIA KDGEK+ TVSS KQPALK
Sbjct: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
Query: 716 AICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVS 775
A D+EDSV N+ATE KD + S TVS QKQPALKAT+D++DSVS I TEIKDG++SGTVS
Sbjct: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
Query: 776 SQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAG-- 833
S+K+PA KATS +KDS SNI E KDG+I T E + EE + LN + G
Sbjct: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEED-SVLNIARGKE 306
Query: 834 -------VSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSV 886
VS +K+ A K +K S NI G S T + P LKAT + ++SV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 887 LNTATKMKDVQTS 899
L+ A + KD + S
Sbjct: 367 LSIAREEKDGEKS 379
Score = 263 bits (671), Expect = 1e-69
Identities = 176/386 (45%), Positives = 226/386 (58%), Gaps = 26/386 (6%)
Query: 569 TVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITRE 628
+VSS+K P KA+S +KDSV NIA K+G + VSS+K+P+ +ATSDEKDS SNI E
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 629 KKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKD 688
K+G+ S VS QK A K ++ S+L IA G KS TVSS+K P KATSD+ D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 689 SVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPAL 748
S LNIA KDG + TVSS KQPALKA D+EDSV N+ATE KD + SGTVS QKQPAL
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 749 KATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTG 808
KAT+D++DSV NI TEIKDG++S TVSSQKQPA KAT+ ++DSVS IATEIKDG+ GT
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGT- 245
Query: 809 ILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTE 868
VS +K+ A K +K S NI G S T
Sbjct: 246 -------------------------VSSRKKPALKATSDEKDSFSNITREKKDGEISRTV 280
Query: 869 YPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVK 928
E LKAT + ++SVLN A +D + + + A + + + N + K
Sbjct: 281 TSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKK 340
Query: 929 NQIHSRDDLDDIIQSSQTVSEDGDSL 954
+ SR + + S++ DS+
Sbjct: 341 DGETSRTVSSQKPPALKATSDEEDSV 366
Score = 237 bits (604), Expect = 7e-62
Identities = 177/424 (41%), Positives = 227/424 (53%), Gaps = 40/424 (9%)
Query: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
VSSQKQPA K TSD DSVSN ATEIK+ SGTV + + D+V+ TE
Sbjct: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
Query: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139
+ +S +S K+I + + L A +T +S
Sbjct: 68 KEGQQSGTVSPQKQSAWKVIFKKKVS----------------LLNIATRITGGG---KSG 108
Query: 140 NISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPE 199
+S + ++ S+ +++ D+A I TE K+G Q VS +
Sbjct: 109 TVS----SQKQPASKATSDKTDSALNI-ATEI----------KDGL------QCGTVSSQ 147
Query: 200 QPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSP 259
+ P T + D +S D S SS++ P T E D A KD
Sbjct: 148 KQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGE 207
Query: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
VSSQKQPA KAT+D++DSVS IATEIK+G SGTVSS+K+PA KATSDEKDS SNI
Sbjct: 208 KSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNI 267
Query: 320 ATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSD 379
E K G+ S TV+ +K + K ++ S+LNIA G K+ VSS+K+PA KATSD
Sbjct: 268 TREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSD 327
Query: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
+ DS NI E KDG TVSSQK PALKAT+DEEDSV +IA E KDGEKS TVSS++
Sbjct: 328 EKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQP 387
Query: 440 PALK 443
P LK
Sbjct: 388 PGLK 391
Score = 137 bits (345), Expect = 8e-32
Identities = 116/342 (33%), Positives = 156/342 (45%), Gaps = 40/342 (11%)
Query: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQC 61
V +L A + S VSSQKQPA K TSDK DS N ATEIKD + GTV +
Sbjct: 92 VSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPA 151
Query: 62 LNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYL 121
L + D+V+ TE + +S +S P K +
Sbjct: 152 LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE------------------ 193
Query: 122 LDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVD 181
D T+ K +SE T+S Q L A D+ ++ ++ + D
Sbjct: 194 -DSVLNIATEIKDGEKSE-----------TVSSQKQPALKATT--DEEDSVSIIATEIKD 239
Query: 182 KEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLT 241
E + VS + P T ++D S D S +SE+P T
Sbjct: 240 GE--------KSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKAT 291
Query: 242 LKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQ 301
E D A ++D +VSS+K+PA KATSD+KDS SNI E K+G S TVSSQ
Sbjct: 292 SDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQ 351
Query: 302 KQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVI 343
K PA KATSDE+DSV +IA E K G++S TVS ++ KV+
Sbjct: 352 KPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVM 393
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 561 bits (1445), Expect = e-159
Identities = 353/887 (39%), Positives = 518/887 (58%), Gaps = 107/887 (12%)
Query: 701 EKTRTVSSP--------KQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATS 752
E TR V P + LK + +DSVPN A KD Q S + A +
Sbjct: 475 EDTRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQ 534
Query: 753 DKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEY 812
+++ S +N P ++++ ++ + + A ++ + AT+ + G+++
Sbjct: 535 EREGSENNQP-QVEEERKKHRNNEMEVSA---------NIHDGATDDAEDDDDDDGLIQK 584
Query: 813 TFNVMFD--QIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYP 870
+ D Q K S+G + Q + + +K+ S ++ + + G
Sbjct: 585 RKSGETDHQQFPRKENKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFG--------- 635
Query: 871 ENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQ 930
K S+L D +S L E E + ++ N + +VKNQ
Sbjct: 636 ------------KASLLTGGLLQVDDDSS------LSEIDEDEGRPTKKTSNEKNKVKNQ 677
Query: 931 IHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKR 990
I S DD+DD+ QSS+T SED + + KN +LLI+Q M+CKD V LLKI++ +R
Sbjct: 678 IQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCER 737
Query: 991 LIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQ 1050
L++LK NHCE L VKI+K+++K +VLQ+ +SE +EIKSQL+H+ +E E+ELCSLRF++ Q
Sbjct: 738 LLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQ 797
Query: 1051 EKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET 1110
E++KRRN + +++K+RE+LR EEQYR E +V + ++ +L++ E+EL+T +N NQV +
Sbjct: 798 EEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQE 857
Query: 1111 -----------------------------------------------DEKEDLLHENRLM 1123
+E++DL H+N ++
Sbjct: 858 RNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSML 917
Query: 1124 QDEIARLRLEKDTIKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQ 1181
Q+EIA LRLE DTIKNQN EKK +D +IVK K+EDLQK +K+N ETL +TI+ Y+G+
Sbjct: 918 QEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGR 977
Query: 1182 LAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGT 1241
L+ LT EN L SKLE +++S++RLE E++SYH RL AA D DQS +SKR+ ELAFQ
Sbjct: 978 LSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRA 1037
Query: 1242 VDKCRHLQENLNSHVL-------ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHV 1294
D+C LQ+ +N V ILS QL K ESK L+ E H+T +AL+EK L E V
Sbjct: 1038 RDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERV 1097
Query: 1295 QSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKA 1350
Q +L Q Q QMK++E+ Y++ + K I KQ ER QL+ +NMLL+QQLDDA NKA
Sbjct: 1098 QKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKA 1157
Query: 1351 DNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAER 1410
DN+EK ++NIQ + A VQ LQAE K LLLEE NK L++E NH KE++ QYE EKAER
Sbjct: 1158 DNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAER 1217
Query: 1411 EVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQL 1470
EV VRQLQQ+ D L K S ++A L+ +SR+ LE+ QD +KKL Q+R+Q QE QD+
Sbjct: 1218 EVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRH 1277
Query: 1471 TATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSL 1517
T +RC ++M+ QKLE ++ ++ +KKQ D+IE L+K L +++L
Sbjct: 1278 TEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANL 1324
Score = 104 bits (260), Expect = 6e-22
Identities = 164/728 (22%), Positives = 299/728 (41%), Gaps = 120/728 (16%)
Query: 857 TRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKR 916
TR G + E PE LK TIE K+SV N A MKDVQTS AE DLE+ASE EQ+R
Sbjct: 477 TRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQER 536
Query: 917 LEEYENNQPQVKNQ--------------IHSR--------DDLDDIIQSSQTVSEDGDSL 954
E ENNQPQV+ + IH DD D +IQ ++ D
Sbjct: 537 -EGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQF 595
Query: 955 -------------CCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHC-- 999
K V ++ + K+ V+ L L+++ D+
Sbjct: 596 PRKENKEYASSGPALQMKEV-KSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLS 654
Query: 1000 ---EQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSL------RFAIQQ 1050
E +K N+ + ++ +I +++ + E E C L F +
Sbjct: 655 EIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSS--ETASEDCELPHSSYKNFMLLI 712
Query: 1051 EKKKRRNVEEVHQ-KVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSE 1109
E+ + V K+++ E ++ + + + +K E ++ ++SE
Sbjct: 713 EQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNV---LQRELSE 769
Query: 1110 TDE-KEDLLHENRLMQDEIARLR--LEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKA--- 1163
T E K L H+ + E+ LR L ++ K +N + Y K E ++RK E +K
Sbjct: 770 TKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEV 829
Query: 1164 ---LKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY-----HC 1215
L+ + +TL + L + E + +L +++ +R + + ++
Sbjct: 830 KQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEI 889
Query: 1216 RLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKT 1275
+ + + + SHS + +++L+ H L + +L L++ +++++
Sbjct: 890 EMAQKKMNSENSHSHEEEKDLS---------HKNSMLQEEIAMLRLEIDTIKNQNQE--- 937
Query: 1276 ELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE-RFCQLKK 1334
KEK FE +LK + + +D++K K T+ + I + R L
Sbjct: 938 ---------KEKKC-FE----DLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTA 983
Query: 1335 QNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNL-QAECRKHRLLLEEDNKMLVNEL 1393
+N +L +L++ + + E + + +R A + + Q+E K L EL
Sbjct: 984 ENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKREL-----------EL 1032
Query: 1394 NHSKEK-ECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDS 1452
+ + EC ++K +V+ L+ + + + T++ L++ LE +
Sbjct: 1033 AFQRARDECSRLQDKMNFDVS--NLKDNNEILSQQLFKTESKLNS-------LEIEFHHT 1083
Query: 1453 RKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKIL 1512
R L + + +Q L+ T KEME QK + E V + K I KQ+ ERL ++
Sbjct: 1084 RDALREKTLGLERVQKDLSQTQCQMKEME---QKYQNEQVKVNKYIGKQESVEERLSQLQ 1140
Query: 1513 QHSSLMLQ 1520
+ L+ Q
Sbjct: 1141 SENMLLRQ 1148
Score = 85.5 bits (210), Expect = 4e-16
Identities = 260/1385 (18%), Positives = 527/1385 (38%), Gaps = 192/1385 (13%)
Query: 137 ESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEG----KALPATGQ 192
+++N+ +P T SQQS +NL+A G +T N +FED++ D + ++LP T
Sbjct: 269 DTKNVPKPSLAKLMTASQQSRKNLEATYGTVRTGNRTLFEDRDSDSQDEVVVESLPTTSI 328
Query: 193 KANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAA 252
K F+H + + S +S P L +KE +P+
Sbjct: 329 KVQ-------CFSHPTYQSPDLLPK---------PSHKSLANPGL----MKE-EPTKPGI 367
Query: 253 MRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDE 312
++++ G + P E+ +D+ V +
Sbjct: 368 AKKEN----GIDIIESAPLEQTNNDNLTYVDEV--------------------------H 397
Query: 313 KDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQP 372
K++ S++ + + GQ+ SP + F +K ++ G + + Q +
Sbjct: 398 KNNRSDMMSALGLGQEEDIESPWDSESISENFPQK--YVDPLAGAADGKEKNIGNEQAED 455
Query: 373 ASKATSDKTDSALNIATEIKDGLQCG-TVSSQKQPA----LKATTDEEDSVSNIATEIKD 427
S + S +++D G V+ + P LK T + +DSV N A +KD
Sbjct: 456 VFYIPSCMSGSRNFKMAKLEDTRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKD 515
Query: 428 GEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGT----VSSQKPPALTATSDEE 483
+ S + A + + + S +N ++ +K VS+ T ++++
Sbjct: 516 VQTSKAAEHDLEVASEEEQEREGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDD 575
Query: 484 GSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQ---- 539
+ ++ K GE RK+ A+S + +K+ S++ +
Sbjct: 576 DDDDGLIQKRKSGETDHQQFPRKENKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFG 635
Query: 540 KPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGE 599
K L G G+ + + D S E P K +S EK+ V N + D +
Sbjct: 636 KASLLTG---------GLLQVDDDSSLSEIDEDEGRP-TKKTSNEKNKVKNQIQSMDDVD 685
Query: 600 KTKRVSSRKKPSLEATSDEKDSF----SNITREKKDGEISRKV-----SSQKPPALKGTS 650
+ S E +F + E KD K+ S ++ LK
Sbjct: 686 DLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNH 745
Query: 651 DEEDSVLGIARENKDGEKSRTVSSEK--PPGLKATSDEKDSVLNIARG--KKDGEKTRTV 706
E +V E+K R +S K L+ E + L R ++ EK R
Sbjct: 746 CELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNA 805
Query: 707 SSPKQPALKAICDKEDSVPNMATEKKDEQIS--------GTVSCQKQPALKATSDKKDSV 758
+ + + + KE+ K+ ++S TV ++ +D + +
Sbjct: 806 DTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQL 865
Query: 759 SNIPTE--IKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGT------GIL 810
S ++DG + +S QK+ + ++ S+ E KD + + +L
Sbjct: 866 SREQNARMLQDGILTNHLSKQKEIEMAQKKMNSEN-SHSHEEEKDLSHKNSMLQEEIAML 924
Query: 811 EYTFNVMFDQIEEKFTSLNKSAGVSPQK-QSAQKVIFKKKVSLLNIATRITGGWKSGT-- 867
+ + +Q +EK + + +K + QK I + + +L ++ G T
Sbjct: 925 RLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAE 984
Query: 868 ---------EYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMA---SEGEQK 915
++ L+A +E+ +S L A + D S ++++LE+A + E
Sbjct: 985 NAMLNSKLENEKQSKERLEAEVESYHSRL--AAAIHDRDQSETSKRELELAFQRARDECS 1042
Query: 916 RLEEYEN--------NQPQVKNQI---------------HSRDDLDDIIQSSQTVSEDGD 952
RL++ N N + Q+ H+RD L + + V +D
Sbjct: 1043 RLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLS 1102
Query: 953 SLCCNCKNVILLIDQHEMKCKDCV--------HLLKIKNTFCLWKRLIKLKDNHCEQLRV 1004
C K + ++K + L ++++ L ++ + N +
Sbjct: 1103 QTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEK 1162
Query: 1005 KIRKLKNK-ASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQ 1063
+ ++++ +++QK +E E+ L+ EL E L+ Q + ++ E V +
Sbjct: 1163 TVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVR 1222
Query: 1064 KVREKLRIT-EEQYRIEA--DVTKPIKPALKSAEVELKTG-GNNSNQVSET-DEKEDLLH 1118
+++++L T ++Q EA +VT + L+ +LK G NQ+ E D + +
Sbjct: 1223 QLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVR 1282
Query: 1119 ENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACY 1178
MQD + +LEKD K + KK + K E+LQK L A
Sbjct: 1283 CAEKMQDH--KQKLEKDNAKLKVTVKKQMD-------KIEELQKNLLN-----ANLSEDE 1328
Query: 1179 SGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY-------HCRLNAARCDHDQSHSSK 1231
QL L + +L L+++ + LE E+ + +LN H
Sbjct: 1329 KEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDL 1388
Query: 1232 RDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVF 1291
+ + ++K +H ++L + + + ++K+++L+ EL + + +++K
Sbjct: 1389 KTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEEL-LSMKTVQKKCEKL 1447
Query: 1292 EHVQSELKQKQSQMKD------IEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDD 1345
+ + +L+Q+ ++ +E Y + +QE +LK+ N+ LQ Q
Sbjct: 1448 QKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQAAS 1507
Query: 1346 ARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEK 1405
N +E +++++ + R+++L++E K + E+ NK + + +E + K
Sbjct: 1508 QENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLYLEELKVRK 1567
Query: 1406 EKAER 1410
+ +
Sbjct: 1568 SLSSK 1572
Score = 58.9 bits (141), Expect = 4e-08
Identities = 103/555 (18%), Positives = 218/555 (39%), Gaps = 69/555 (12%)
Query: 1015 VLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQ------EKKKRRNVEEVHQKVREK 1068
++QKR S + + + + E KE S A+Q EK+KR + E V+ V K
Sbjct: 581 LIQKRKSGETDHQQFPRKE----NKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGK 636
Query: 1069 --------LRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHEN 1120
L++ ++ E D + +P K++ + K NQ+ D+ +DL +
Sbjct: 637 ASLLTGGLLQVDDDSSLSEIDEDEG-RPTKKTSNEKNKV----KNQIQSMDDVDDLTQSS 691
Query: 1121 RLMQDEIARLRLEKDTIKNQNLEKKYL----KDFEIVKRKHEDLQKALKRNGETLAKTIA 1176
++ L + KN L + L KD + K +D + +R E
Sbjct: 692 ETASEDC---ELPHSSYKNFMLLIEQLGMECKD-SVSLLKIQDAALSCERLLELKKNHCE 747
Query: 1177 CYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQEL 1236
+ ++ + D+ L+ +L + +E + +LE + + L + R +Q +R+ +
Sbjct: 748 LLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADT 807
Query: 1237 AFQGTVDKCRHLQENLNSHVLI---LSLQLSKAESKSRVLKTELHYTGEALKEKALVFEH 1293
++ ++ R +E V + L L L E + R +K+ L+ + +
Sbjct: 808 LYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSR 867
Query: 1294 VQSE-------LKQKQSQMKDIE----KMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQ 1342
Q+ L S+ K+IE KM ++ E+ + + L+++ +L+ +
Sbjct: 868 EQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLE 927
Query: 1343 LDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEE--------------DNKM 1388
+D +N+ +EK + ++LQ +++ L + +N M
Sbjct: 928 IDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAM 987
Query: 1389 LVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENG 1448
L ++L + K+ + + E E + RD + + C+ L++
Sbjct: 988 LNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDK 1047
Query: 1449 MQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERL 1508
M + ++ + + QL T E LE+E R ++++ +ER+
Sbjct: 1048 MNFD---VSNLKDNNEILSQQLFKT-------ESKLNSLEIEFHHTRDALREKTLGLERV 1097
Query: 1509 EKILQHSSLMLQVFE 1523
+K L + ++ E
Sbjct: 1098 QKDLSQTQCQMKEME 1112
Score = 35.4 bits (80), Expect = 0.42
Identities = 95/490 (19%), Positives = 198/490 (40%), Gaps = 95/490 (19%)
Query: 691 LNIARGKKDGEKTRTVSSPKQPALKAICDK---EDSVPNMATEKKDEQISGTVSCQKQPA 747
L+ A K D ++ ++ Q AI K E ++ E++++++ + K+
Sbjct: 1150 LDDAHNKADNKEKTVINIQDQ--FHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQ 1207
Query: 748 LKATSDKKDS---VSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKD--G 802
+ ++K + V + E+ D + ++S + + + TS + ++ + ++K G
Sbjct: 1208 YQYENEKAEREVVVRQLQQELADTLKKQSMS---EASLEVTSRYRINLEDETQDLKKKLG 1264
Query: 803 QIRGTGILEYTFNVMFDQIEEKFTSLNKSAG-VSPQKQSAQKVIFKKKVSLLNIATRITG 861
QIR + +++ T + A + KQ +K K KV++ +I
Sbjct: 1265 QIRN----------QLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIE- 1313
Query: 862 GWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGE-------- 913
E +NL + + K + K+ +++ S D EM E
Sbjct: 1314 ------ELQKNLLNANLSEDEKEQL----KKLMELKQSLECNLDQEMKKNVELEREITGF 1363
Query: 914 -------QKRLEEYENNQPQVKNQIH-SRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLI 965
+K+L EYEN + + S+ ++D I + +D L
Sbjct: 1364 KNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDD-------------LT 1410
Query: 966 DQHEMKCKDCVHLLKIKNTFCLWKRLIKLK--DNHCEQLRVKIRKLKNKASVLQKRISE- 1022
+ E C+HL KN L + L+ +K CE+L+ +KL+ + L+ I
Sbjct: 1411 AELETAGSKCLHL-DTKNQI-LQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERN 1468
Query: 1023 ----------KEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQ------KVR 1066
K+EI+ + + EI E KE + +Q + + N+E+ + K +
Sbjct: 1469 MVELGQVKQYKQEIEERARQEIAEKLKE---VNLFLQAQAASQENLEQFRENNFASMKSQ 1525
Query: 1067 EKLRITEEQYRI------EADVTKPIKPALKSAEV-ELKTGGNNSNQVSETDEKEDLLHE 1119
+LRI + + + + D K K + ELK + S+++++T+E+ ++
Sbjct: 1526 MELRIKDLESELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNT 1585
Query: 1120 NRLMQDEIAR 1129
L++ + +R
Sbjct: 1586 KLLVEKQQSR 1595
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 528 bits (1361), Expect = e-149
Identities = 299/559 (53%), Positives = 387/559 (69%), Gaps = 12/559 (2%)
Query: 912 GEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEM 970
GE RL + N + +VK+QI+ DDL+DI SS+ SED + + +N +LLI Q M
Sbjct: 351 GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGM 410
Query: 971 KCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQL 1030
+CKD V L K KN R I+ + +CE+L+VK +K+KN SVLQK +SE ++ KSQ
Sbjct: 411 ECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQS 470
Query: 1031 KHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPAL 1090
+H+ L+ +K+LC+LRF +QQ++++R EE+++K E+L+I EEQYR + +V K K L
Sbjct: 471 EHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTL 530
Query: 1091 KSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDTIKNQN--LEKKYL 1147
KS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DTIK+QN E KY
Sbjct: 531 KSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYF 590
Query: 1148 KDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLE 1207
KD EI+K +EDL+K LKRN ETL KTI YS +L L DENT L S+L+K+++S RLE
Sbjct: 591 KDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLE 650
Query: 1208 TEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAE 1267
TEM+SY CRL AA CDHDQ SSKRD +LAFQ TV++ HLQE+ NSH+ ILS QLSKAE
Sbjct: 651 TEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAE 710
Query: 1268 SKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE 1327
S S L+TELHY EALKEK L EH+Q L + Q +++DIE MY++ +EK + KQ+
Sbjct: 711 STSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQ 770
Query: 1328 R----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLE 1383
QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ V+ LQAECRK LE
Sbjct: 771 SVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRK----LE 826
Query: 1384 EDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT 1443
E+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK +A+L+ SS
Sbjct: 827 ENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRI 886
Query: 1444 YLENGMQDSRKKLDQMRSQ 1462
LE+ Q +KKL QMRSQ
Sbjct: 887 NLEDEAQSLKKKLGQMRSQ 905
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 528 bits (1361), Expect = e-149
Identities = 299/559 (53%), Positives = 387/559 (69%), Gaps = 12/559 (2%)
Query: 912 GEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEM 970
GE RL + N + +VK+QI+ DDL+DI SS+ SED + + +N +LLI Q M
Sbjct: 351 GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIKQSGM 410
Query: 971 KCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQL 1030
+CKD V L K KN R I+ + +CE+L+VK +K+KN SVLQK +SE ++ KSQ
Sbjct: 411 ECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQS 470
Query: 1031 KHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPAL 1090
+H+ L+ +K+LC+LRF +QQ++++R EE+++K E+L+I EEQYR + +V K K L
Sbjct: 471 EHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTL 530
Query: 1091 KSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDTIKNQN--LEKKYL 1147
KS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DTIK+QN E KY
Sbjct: 531 KSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYF 590
Query: 1148 KDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLE 1207
KD EI+K +EDL+K LKRN ETL KTI YS +L L DENT L S+L+K+++S RLE
Sbjct: 591 KDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLE 650
Query: 1208 TEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAE 1267
TEM+SY CRL AA CDHDQ SSKRD +LAFQ TV++ HLQE+ NSH+ ILS QLSKAE
Sbjct: 651 TEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAE 710
Query: 1268 SKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE 1327
S S L+TELHY EALKEK L EH+Q L + Q +++DIE MY++ +EK + KQ+
Sbjct: 711 STSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQ 770
Query: 1328 R----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLE 1383
QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ V+ LQAECRK LE
Sbjct: 771 SVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRK----LE 826
Query: 1384 EDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT 1443
E+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK +A+L+ SS
Sbjct: 827 ENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRI 886
Query: 1444 YLENGMQDSRKKLDQMRSQ 1462
LE+ Q +KKL QMRSQ
Sbjct: 887 NLEDEAQSLKKKLGQMRSQ 905
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 528 bits (1359), Expect = e-149
Identities = 298/559 (53%), Positives = 387/559 (69%), Gaps = 12/559 (2%)
Query: 912 GEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEM 970
GE RL + N + +VK+QI+ DDL+DI SS+ SED + + +N +LLI+Q M
Sbjct: 351 GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSDDENFMLLIEQSGM 410
Query: 971 KCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQL 1030
+CKD V L K KN R I+ + +CE+L+VK +K+KN SVLQK +SE ++ KSQ
Sbjct: 411 ECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQS 470
Query: 1031 KHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPAL 1090
+H+ L+ +K+LC+LRF +QQ++++R EE+++K E+L+I EEQYR + +V K K L
Sbjct: 471 EHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTL 530
Query: 1091 KSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDTIKNQN--LEKKYL 1147
KS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DTIK+QN E KY
Sbjct: 531 KSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYF 590
Query: 1148 KDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLE 1207
KD EI+K +EDL+K LKRN E L KTI YS +L L DENT L S+L+K+++S RLE
Sbjct: 591 KDIEIIKENNEDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLE 650
Query: 1208 TEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAE 1267
TEM+SY CRL AA CDHDQ SSKRD +LAFQ TV++ HLQE+ NSH+ ILS QLSKAE
Sbjct: 651 TEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNSHIQILSQQLSKAE 710
Query: 1268 SKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE 1327
S S L+TELHY EALKEK L EH+Q L + Q +++DIE MY++ +EK + KQ+
Sbjct: 711 STSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQ 770
Query: 1328 R----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLE 1383
QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ V+ LQAECRK LE
Sbjct: 771 SVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRK----LE 826
Query: 1384 EDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT 1443
E+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK +A+L+ SS
Sbjct: 827 ENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLLLEAMLEISSERRI 886
Query: 1444 YLENGMQDSRKKLDQMRSQ 1462
LE+ Q +KKL QMRSQ
Sbjct: 887 NLEDEAQSLKKKLGQMRSQ 905
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 380 bits (975), Expect = e-105
Identities = 382/1290 (29%), Positives = 581/1290 (45%), Gaps = 168/1290 (13%)
Query: 156 SAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHIS 215
+AE+ CG M + + K + G A E PL T + +
Sbjct: 184 TAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLV 243
Query: 216 TRFLGGMDSLTSSEESS--ERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEK 273
+ T E + ER P + +L E P A++ S + Q EK
Sbjct: 244 EK--------TPDEAAPLVERTPDTAESLVEKTPDEAASLVEG-------TSDKIQCLEK 288
Query: 274 ATSDD-KDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTV 332
ATS + S EI S K+ +EK T K IA E K+ +
Sbjct: 289 ATSGKFEQSAEETPREI--------TSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIM 340
Query: 333 SPQKQSAWKVIFKKKVSLLNIA-----TRIMGGGKSGTVSSQKQPASKATSDKTDSALNI 387
SP K+++ K + K IA T + G + S++ + K S I
Sbjct: 341 SPAKETSEKFTWAAKGRPRKIAWEKKETPVKTGCVARVTSNKTKVLEKGRSKM------I 394
Query: 388 ATEIKDGLQCGTVSSQKQPA-LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATT 446
A K+ + + Q+ P+ K DEE S D S++ Q + +
Sbjct: 395 ACPTKESSTKASANDQRFPSESKQEEDEEYSC--------DSRSLFESSAKIQVCIPESI 446
Query: 447 DEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRK 506
+K V I E+++ K KP A + + SV NK E + R
Sbjct: 447 YQK--VMEINREVEEPPK-------KPSAFKPAIEMQNSV-----PNKAFELKNEQTLRA 492
Query: 507 KPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL-KGTSDEE-DSVLGIARE--NK 562
P S +KD N D E + SQK L K T +E D + G E NK
Sbjct: 493 DPMFPPESKQKDYEEN----SWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNK 548
Query: 563 DGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSF 622
DG LKA+ K S+ A KD + K K + E ++ + S
Sbjct: 549 DGL------------LKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSV 596
Query: 623 SNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKA 682
N E K+ + R D +L + KD E++ S L
Sbjct: 597 PNKALELKNEQTLRA----------------DEILPSESKQKDYEEN----SWDTESLCE 636
Query: 683 TSDEKDSVLNIARGKKDGEKT--RTVSSP-KQPALKAICDKEDSVPNMATEKKDEQISGT 739
T +KD L A +K+ +K + SP K LKA C + S+P A E D Q
Sbjct: 637 TVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKA 696
Query: 740 VSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGT----VSSQKQPAWKATSVKKDSVSNI 795
+K A + + + SV N E+K+ Q S KQ ++ +S +S+
Sbjct: 697 EPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCET 756
Query: 796 ATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNI 855
++ + + + T D+I K SP K + KVS+
Sbjct: 757 VSQ------KDVCLPKATHQKEIDKINGKLEE-------SPDNDGFLKAPCRMKVSIPTK 803
Query: 856 ATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQK 915
A + E PE + IE + SV N A ++K+ QT D SE +QK
Sbjct: 804 ALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQT---LRADQMFPSESKQK 860
Query: 916 RLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDC 975
++EE + ++ + +D +C +D+ K +D
Sbjct: 861 KVEENSWDSESLRETVSQKD------------------VCVPKATHQKEMDKISGKLEDS 902
Query: 976 VHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEIL 1035
L KI +T +R +L+ +HCEQ K+ ++K K VL+K++SE +EIKSQL+++ +
Sbjct: 903 TSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKV 962
Query: 1036 ELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEV 1095
+ E+ELCS+R + QE++KRRN + +++K+RE+L EEQ+R E +V + ++ AL+ ++
Sbjct: 963 KWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDI 1022
Query: 1096 ELKTGGNNSNQVSETDEKED-LLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEI 1152
ELK+ +N NQVS T E E+ LLHEN +++ EIA L+LE T+K+Q EK KY +D +I
Sbjct: 1023 ELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKI 1082
Query: 1153 VKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQS 1212
+K K+ +LQ LK E+L K + YSGQL L ENT L SKL K+++ ++ LE E++S
Sbjct: 1083 LKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAEIES 1141
Query: 1213 YHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------ILSLQLSK 1265
+H RL +A DHDQ +S++ QE AF D C LQ +N V +L LS+
Sbjct: 1142 HHPRLASAVQDHDQIVTSRKSQEPAFHIAGDAC--LQRKMNVDVSSTIYNNEVLHQPLSE 1199
Query: 1266 AESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK 1325
A+ KS+ LK L+Y G+AL+E LV EH Q + ++ Q QMK+ E MY++ + + K E+
Sbjct: 1200 AQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQ 1259
Query: 1326 QE----RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLL 1381
QE + QL+ +NM LQQQL A KADN+ K ++I L+ + + H L
Sbjct: 1260 QESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF--------LERKMQHH--L 1309
Query: 1382 LEEDNKMLVNELNHSKEKECQYEKEKAERE 1411
L+E N+ + N NH K + QYEKEKAE E
Sbjct: 1310 LKEKNEEIFNYNNHLKNRIYQYEKEKAETE 1339
Score = 70.5 bits (171), Expect = 1e-11
Identities = 227/1092 (20%), Positives = 408/1092 (37%), Gaps = 142/1092 (13%)
Query: 492 ENKDGEKSRTVSS-RKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDE 550
E E R ++S K+ + K T K I KK+ +S K + K T
Sbjct: 295 EQSAEETPREITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAA 354
Query: 551 EDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKP 610
+ IA E K+ +T + K EK IA K+ + ++ P
Sbjct: 355 KGRPRKIAWEKKE-TPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFP 413
Query: 611 SLEATSDEKDSFSNITRE-----------------KKDGEISRKVSS--QKPPALKGTSD 651
S E+ +E + +S +R +K EI+R+V +KP A K +
Sbjct: 414 S-ESKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIE 472
Query: 652 EEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQ 711
++SV A E K+ + R P S +KD N S +
Sbjct: 473 MQNSVPNKAFELKNEQTLRA-----DPMFPPESKQKDYEEN--------------SWDSE 513
Query: 712 PALKAICDKEDSVPNMATEKKDEQISGTV--SCQKQPALKATSDKKDSVSNIPTEIKDGQ 769
+ + K+ +P +K+ ++I+G + S K LKAT K S+ E+KD Q
Sbjct: 514 SLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQ 573
Query: 770 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLN 829
K A++ + + SV N A E+K+ Q + + + D E + + +
Sbjct: 574 TFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEENSWDTES 633
Query: 830 KSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNT 889
VS + K +K++ +N G G+ + L LKA K S+
Sbjct: 634 LCETVSQKDVCLPKAAHQKEIDKIN-------GKLEGSPVKDGL--LKANCGMKVSIPTK 684
Query: 890 ATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSS----- 944
A ++ D+QT + A E + + N ++KN+ R D+I+ S
Sbjct: 685 ALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLR--ADEILPSESKQKD 742
Query: 945 -QTVSEDGDSLC--CNCKNVILL-------IDQHEMKCKDCVHLLKIKNTFCLWKRLIKL 994
+ S D +SLC + K+V L ID+ K ++ C K I
Sbjct: 743 YEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPT 802
Query: 995 KDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKK 1054
K ++ + K S + I E++ + ++ LEL+ E + + K
Sbjct: 803 KALELMDMQTFKAEPPEKPSAFEPAI----EMQKSVPNKALELKNEQTLRADQMFPSESK 858
Query: 1055 RRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE 1114
++ VEE + E LR T Q DV P K + K G + S +
Sbjct: 859 QKKVEE-NSWDSESLRETVSQ----KDVCVPKATHQKEMD---KISGKLEDSTS-LSKIL 909
Query: 1115 DLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKT 1174
D +H + E+ + E+ T K + ++KK+ ++K+K + K +K E
Sbjct: 910 DTVHSCERAR-ELQKDHCEQRTGKMEQMKKKFC----VLKKKLSEA-KEIKSQLEN---- 959
Query: 1175 IACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQ 1234
Q E ++R L ++ E R+ + + L H + K+
Sbjct: 960 ------QKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQL 1013
Query: 1235 ELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHV 1294
E A + + + ++ NLN Q+S L LH KE A++
Sbjct: 1014 EQALRIQDIELKSVESNLN--------QVSHTHENENYL---LHENCMLKKEIAML---- 1058
Query: 1295 QSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQE 1354
+ E+ + Q ++ E Y +++ + + +LK++++ + + K E
Sbjct: 1059 KLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAE 1118
Query: 1355 KAILNIQARCDARVQNLQAECRKHRLLLE---EDNKMLVNELN------HSKEKECQYEK 1405
+L + + + L+AE H L +D+ +V H C K
Sbjct: 1119 NTMLTSKLKEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDACLQRK 1178
Query: 1406 EKAEREVAVRQ---LQQKRDDVLNKGSATKALL----DASSRHCTYLENGMQDSRKKLDQ 1458
+ + L Q + K + K L DA + E+ +D R+ Q
Sbjct: 1179 MNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQ 1238
Query: 1459 MRSQFQEIQDQLTATIRCTKEMEGDTQK---LEVEHVMMRKII----KKQDDQ------I 1505
M+ Q++ + T++ E QK L+ +++ +++ + KK D++ I
Sbjct: 1239 MKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDI 1298
Query: 1506 ERLEKILQHSSL 1517
LE+ +QH L
Sbjct: 1299 HFLERKMQHHLL 1310
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 371 bits (953), Expect = e-102
Identities = 331/1189 (27%), Positives = 559/1189 (47%), Gaps = 167/1189 (14%)
Query: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATT-DEKDSVSNIATEIKDGEKSGTVSSQ 471
D + S+ + E K+ + ++ P T D + +K +K +VS
Sbjct: 111 DRKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVDDKCPSVSPS 170
Query: 472 KPPALTATSDEEGSVLSIARENKDG-----EKSRTVSSRKKPALKATSDEKDSFSNITRG 526
P +AT E G + RE D + T+ + L + K++
Sbjct: 171 MPENQSATK-ELGQMNLTEREKMDTGVVLLSGNDTLHDLCQSQLPENKESKEA------- 222
Query: 527 KKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKA-SSAEK 585
++D E++ S ++ LKG +++ + +++ E ++ E P +K
Sbjct: 223 EQDSELT---SEEEQERLKGCENKQPQ-----KTSQEPEMAKDCDREDIPIYPVLPHVQK 274
Query: 586 DSVLNIARGKKDGEKTKRVSSRK----------KPSLEATSDEKDSFSNITREKKDGEIS 635
+ I +GK + + ++ + K + A +E+ N TR +I
Sbjct: 275 SEEMWIEQGKLEWKNQLKLVINELKQRFGEIYEKYKIPACPEEEPLLDNSTRGTDVKDIP 334
Query: 636 RKVSSQKPPALKGTSDEEDSVLGIAR--ENKDGEKSRTVSSEKPPGLKATSDEKDSVLNI 693
+++ P G +E+ S + ++ E +K ++ + P S ++ V
Sbjct: 335 FNLTNNIP----GCEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQS 390
Query: 694 ARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSD 753
+ E + +P + I + + N A+ KK + P +
Sbjct: 391 SSKFHLHENKLDCDNDNKPGIGHIFSTDKNFHNDASTKK----------ARNPEVVMVEM 440
Query: 754 KKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEI-KDGQIRGTGILEY 812
K+D ++ Q S + S+ +K+ K +++S++ + + ++ L+
Sbjct: 441 KEDQEFDLQMTKNMNQNSDSGSTNN---YKSLKPKLENLSSLPPDSDRTSEVYLHEELQQ 497
Query: 813 T---FNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEY 869
F + +EE+F +L K + K + ++ + +T ++G GT
Sbjct: 498 DMQKFKNEVNTLEEEFLALKK------EDVQLHKDVEEEMEKHRSNSTELSGTLTDGT-- 549
Query: 870 PENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKR-LEEYENNQPQVK 928
T+ N + LN Q + GE R ++ N + +VK
Sbjct: 550 ---------TVGNDDDGLN---------------QQIPRKENGEHDRPADKTSNEKNEVK 585
Query: 929 NQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLW 988
NQI+ D D ++ S+ SED + +N +LLI+Q M+ KD L +I++TFCL
Sbjct: 586 NQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCLC 645
Query: 989 KRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAI 1048
+ L+KLK+NHC+QL VK+++++N SVLQ +SE ++ K QL+ + +E EKEL LR A+
Sbjct: 646 EHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLAL 705
Query: 1049 QQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNN----- 1103
+QE +++RN + ++ K E+LRI EE+ + + +K L+ EL+T NN
Sbjct: 706 KQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVV 765
Query: 1104 --------------------------------------SNQVSETDEKE-DLLHENRLMQ 1124
++++S +KE DL HE+ ++Q
Sbjct: 766 QERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQ 825
Query: 1125 DEIARLRLEKDTIKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQL 1182
+EIA LRLE DTIKNQN EKKY +D E VK K+++LQK +K N ETL +TI YSGQL
Sbjct: 826 EEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQL 885
Query: 1183 AALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGT- 1241
LT EN L S+LE +++++RLE EM+SY CRL AA D DQS ++ RD +L FQ T
Sbjct: 886 NNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTA-RDLKLDFQRTR 944
Query: 1242 ------VDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQ 1295
DK + L + ILS +LS AESK L+ +LH T +AL ++L+ E VQ
Sbjct: 945 QEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQ 1004
Query: 1296 SELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKAD 1351
+L Q Q Q K+ E+MY+ + ++K I KQ ER QL+ +NMLL+QQLDDA KA+
Sbjct: 1005 RDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKAN 1064
Query: 1352 NQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAERE 1411
+QEK IQ + + +NLQAE K L L+E NK L++E NH KE+ Q EKEKA R+
Sbjct: 1065 SQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRK 1124
Query: 1412 VAVRQLQQ----------KRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRS 1461
+ + + Q+ ++VL T + A + C L+ + ++++ ++S
Sbjct: 1125 IDLTEAQETVPSRCLHLDAENEVLQL-QQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKS 1183
Query: 1462 QFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEK 1510
+ + + + KL +E ++I +K ++ I L+K
Sbjct: 1184 YMER---------NMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQK 1223
Score = 62.4 bits (150), Expect = 3e-09
Identities = 100/527 (18%), Positives = 216/527 (40%), Gaps = 72/527 (13%)
Query: 1018 KRISEKEEIKSQLKHEI--------LELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKL 1069
K +EK E+K+Q+ E E+ E C L ++ + + K L
Sbjct: 576 KTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASL 635
Query: 1070 RITEEQYRIEADVTKPIKPALKSAEVELKTGGNN----SNQVSETDEKEDLLHENRLMQD 1125
++ + + + K V+LK N N++SET + + L ++ +
Sbjct: 636 PRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWE 695
Query: 1126 EIA---RLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKA------LKRNGETLAKTIA 1176
+ RL L+++ + +N + Y KD E ++ K E+ K LK N L K +
Sbjct: 696 KELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELR 755
Query: 1177 CYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAAR--CDHDQSHSSKRDQ 1234
L + E + +L +++++R + + S L AR + + SH ++++
Sbjct: 756 TVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEK 815
Query: 1235 ELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHV 1294
+L + + L + +L L++ +++++ + + EA+KEK +++
Sbjct: 816 DLFHEDCM---------LQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKN---DNL 863
Query: 1295 QSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQE 1354
Q +K + + + Y N L +N +L +L++ + NQE
Sbjct: 864 QKIIKLNEETLTETILQYSGQLNN-------------LTAENKILNSELENGKQ---NQE 907
Query: 1355 KAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQ-YEKEKAEREVA 1413
+ + +++ CR + + D +L ++ Q + + + +V
Sbjct: 908 RLEIEMESY----------RCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVD 957
Query: 1414 VRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTAT 1473
+ LQ K + + K S ++ +++ L+ + ++R L + + +Q L+ T
Sbjct: 958 MSGLQAKNEILSEKLSNAESKINS-------LQIQLHNTRDALGRESLILERVQRDLSQT 1010
Query: 1474 IRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQ 1520
KE E Q ++E ++K I KQ+ ERL ++ + L+ Q
Sbjct: 1011 QCQKKETE---QMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQ 1054
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 317 bits (812), Expect = 6e-86
Identities = 286/903 (31%), Positives = 438/903 (48%), Gaps = 110/903 (12%)
Query: 573 EKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDG 632
EKP K + + +V N A K+ E+T R + + DE++S+ D
Sbjct: 527 EKPSAFKPAVEMQKTVPNKAFELKN-EQTLRAAQMFPSESKQKDDEENSW--------DS 577
Query: 633 EISRKVSSQKPPAL-KGTSDEE-DSVLGIAREN--KDGEKSRTVSSEKPPGLKATSDEKD 688
E + SQK L K T +E D++ G E+ KDG LK T K
Sbjct: 578 ESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGL------------LKPTCGRKV 625
Query: 689 SVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPAL 748
S+ N A KD E + S K LK C ++ S+PN A E KD + S L
Sbjct: 626 SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLL 685
Query: 749 KATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTG 808
K T +K S+ N E+KD + + + + + S +KD N D +
Sbjct: 686 KPTCGRKVSLPNKALELKDRE-----TFKAAQMFPSESKQKDDEENSW----DFESFLET 736
Query: 809 ILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTE 868
+L+ + +++F +L+ SP K K K+SL N A + E
Sbjct: 737 LLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAE 796
Query: 869 YPENLPTL-----KATIENKNSV-----LNTATKMKDVQTST-PAEQDLEMASEGEQKRL 917
++ + K T EN S N TK +T T E+D+ + Q +
Sbjct: 797 DVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQT 856
Query: 918 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVS----------------------------- 948
+ ++ K S D +II S T +
Sbjct: 857 NKMPTSELGRKEDTKSTSD-SEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSH 915
Query: 949 -EDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIR 1007
E + + N L + D L KI + +R +LK ++CEQ+ K+
Sbjct: 916 FEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKME 975
Query: 1008 KLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVRE 1067
+ KNK VLQK +SE +EIKSQL+++ + E+ELCS+R + QE++KRRNV+ + +K+R
Sbjct: 976 QTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIR- 1034
Query: 1068 KLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDE 1126
EEQ R + +V + ++ L+ ++ELK+ +N NQVS T E E DL HEN +++ E
Sbjct: 1035 ----PEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLKKE 1090
Query: 1127 IARLRLEKDTIKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAA 1184
IA L+LE T+K+Q+ E KY +D +I++ K+ +LQ LK +T+ K + Y QL
Sbjct: 1091 IAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKV 1150
Query: 1185 LTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDK 1244
LT ENT L SKL K+++ ++ LETE++S+H RL +A DHDQS +S+++QELAF D
Sbjct: 1151 LTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGD- 1208
Query: 1245 CRHLQENLNSHVL-------ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSE 1297
LQ +N V +L L +A+ KS+ K L+Y G+ L+E ALV EH Q +
Sbjct: 1209 -APLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQRD 1267
Query: 1298 LKQKQSQMKDIEKMYKSGYNTMEKCIEKQE----RFCQLKKQNMLLQQQLDDARNKADNQ 1353
+ Q QMK E MY++ + ++K E+QE + QL+ +N L+QQL A K N+
Sbjct: 1268 RCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKV-NK 1326
Query: 1354 EKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVA 1413
K +NIQ + + ++H L E N+ + N NH KE+ QYEKEKAEREV+
Sbjct: 1327 SKVTINIQFP--------EMKMQRH---LNEKNEEVFNYGNHLKERIDQYEKEKAEREVS 1375
Query: 1414 VRQ 1416
+++
Sbjct: 1376 IKK 1378
Score = 56.2 bits (134), Expect = 2e-07
Identities = 220/1060 (20%), Positives = 390/1060 (36%), Gaps = 235/1060 (22%)
Query: 282 VSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKK------GQQSGTVSPQ 335
V I E++E P +K A K + + +V N A E+K Q + S Q
Sbjct: 515 VMEINREVEELP-------EKPSAFKPAVEMQKTVPNKAFELKNEQTLRAAQMFPSESKQ 567
Query: 336 K---QSAW------KVIFKKKVSLLNIATRIMGGGKSGTV--SSQKQPASKATSDKTDSA 384
K +++W + + +K V L + SG + S K K T + S
Sbjct: 568 KDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSL 627
Query: 385 LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKA 444
N A E+KD S K LK T + S+ N A E+KD E S LK
Sbjct: 628 PNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKP 687
Query: 445 TTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSS 504
T K S+ N A E+KD E ++Q P+ + D+E EN
Sbjct: 688 TCGRKVSLPNKALELKDRET--FKAAQMFPSESKQKDDE--------EN----------- 726
Query: 505 RKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDG 564
S + +SF T + D + + ++ TL G +E
Sbjct: 727 ---------SWDFESFLE-TLLQNDVCLPKATHQKEFDTLSGKLEE-------------- 762
Query: 565 EKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSN 624
S +K LK + K S+ N A KD E K E S + +FS
Sbjct: 763 ------SPDKDGLLKPTCGMKISLPNKALELKDRETFK---------AEDVSSVESTFSL 807
Query: 625 ITREKKDGEISRKVS-----SQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSE--KP 677
+ + S KV + K A K + +++ +GI + ++ +SE +
Sbjct: 808 FGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRK 867
Query: 678 PGLKATSD---------EKDSVLNIARGKKDGEKT--RTVSSPKQPA-LKAICDKEDSVP 725
K+TSD + L A +K+ + T + SP++P+ + + ++SVP
Sbjct: 868 EDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQNSVP 927
Query: 726 NMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKAT 785
N E K++Q L+A S + + + G++
Sbjct: 928 NKGLEWKNKQ-----------TLRADSTTLSKILDALPSCERGRE--------------- 961
Query: 786 SVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSA---Q 842
+KKD+ I ++ +Q + KF L K + + +S Q
Sbjct: 962 -LKKDNCEQITAKM-------------------EQTKNKFCVLQKELSEAKEIKSQLENQ 1001
Query: 843 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 902
K +++++ + R+T E N+ LK I + + ++
Sbjct: 1002 KAKWEQEL----CSVRLT--LNQEEEKRRNVDILKEKIRPE----------EQLRKKLEV 1045
Query: 903 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 962
+Q LE + L+ +N QV H+ + +D+ + + ++ + V
Sbjct: 1046 KQQLEQTLRIQDIELKSVTSNLNQVS---HTHESENDLFHENCMLKKE---IAMLKLEVA 1099
Query: 963 LLIDQHEMKCK---DCVHLLKIKNTFCLWKRLIKLK--DNHCEQLRVKIRKLKNKASVLQ 1017
L QH++K + + +L+ KN +K K Q R +++ L + ++L
Sbjct: 1100 TLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLT 1159
Query: 1018 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYR 1077
++ EK++ K L+ EI L S Q R+N E + Q
Sbjct: 1160 SKLKEKQD-KEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGD----APLQGI 1214
Query: 1078 IEADVTKPI------KPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLR 1131
+ DV+ I L A+ + K+ N N D L EN L+ + R R
Sbjct: 1215 MNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAG------DDLRENALVSEHAQRDR 1268
Query: 1132 LEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTT 1191
E + + E Y + + V KH + Q++L++ +L L +N
Sbjct: 1269 CETQ-CQMKKAEHMYQNEQDNVD-KHTEQQESLEQ--------------KLFQLESKNRW 1312
Query: 1192 LRSKL--EKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQ 1249
LR +L ++ ++ ++ +Q ++ Q H +++++E+ G HL+
Sbjct: 1313 LRQQLVYAHKKVNKSKVTINIQFPEMKM--------QRHLNEKNEEVFNYG-----NHLK 1359
Query: 1250 ENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKAL 1289
E ++ Q K +++ V + Y LKE L
Sbjct: 1360 ERID--------QYEKEKAEREVSIKKYKYFSNFLKESGL 1391
Score = 48.9 bits (115), Expect = 4e-05
Identities = 178/872 (20%), Positives = 329/872 (37%), Gaps = 126/872 (14%)
Query: 229 EESS--ERPPLSTLTLKEADPSSKAAMRRKDSPPPGKV--SSQKQPAEKATSDDKDSVSN 284
EE+S P T++ K+ KA +++ GK+ S K K T K S+ N
Sbjct: 571 EENSWDSESPCETVSQKDVY-LPKATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSLPN 629
Query: 285 IATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIF 344
A E+K+ S K K T K S+ N A E+K + SP K
Sbjct: 630 KALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKPTC 689
Query: 345 KKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQK 404
+KVSL N A + + ++Q P+ D +++ + + ++ LQ
Sbjct: 690 GRKVSLPNKALELK--DRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQNDVCLP-- 745
Query: 405 QPALKATTDEE-DSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGE 463
KAT +E D++S E S K LK T K S+ N A E+KD E
Sbjct: 746 ----KATHQKEFDTLSGKLEE----------SPDKDGLLKPTCGMKISLPNKALELKDRE 791
Query: 464 KSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNI 523
T ++ ++ +T G + ++ E+ +++++ T ++ I
Sbjct: 792 ---TFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQQERDIGII 848
Query: 524 TRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSA 583
R +D + K PT S LG + K S +S S
Sbjct: 849 ERAPQD-------QTNKMPT---------SELGRKEDTKSTSDSEIIS--------VSDT 884
Query: 584 EKDSVLNIARGKKDGEKT--KRVSSRKKPS-LEATSDEKDSFSNITREKKDGEISR---- 636
+ L A +K+ + T K S +KPS E ++ ++S N E K+ + R
Sbjct: 885 QNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADST 944
Query: 637 ---KVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNI 693
K+ P +G ++D+ I + + + V K S+ K+ +
Sbjct: 945 TLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQ------KELSEAKEIKSQL 998
Query: 694 ARGKKDGEK-----TRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPAL 748
K E+ T++ ++ KE P KK E V Q + L
Sbjct: 999 ENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIRPEEQLRKKLE-----VKQQLEQTL 1053
Query: 749 KATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTG 808
+ + SV++ ++ +S + + + K ++ + E+
Sbjct: 1054 RIQDIELKSVTSNLNQVSHTHES------ENDLFHENCMLKKEIAMLKLEV--------A 1099
Query: 809 ILEYTFNVMFDQIEEKFTSL-NKSAGVSPQKQSAQKVIFKKKVSL---LNIATRITGGWK 864
L++ V ++ E L K+A + + QK + K+ L + T
Sbjct: 1100 TLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLT 1159
Query: 865 SGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQ 924
S + ++ L+ IE+ + L +A + D ++ Q+L S G+ L+ N
Sbjct: 1160 SKLKEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGDAP-LQGIMN-- 1216
Query: 925 PQVKNQIHSRDDLDDIIQSSQTVSED--------GDSLCCNCKNVILLIDQHEMKCKDCV 976
V N I++ + L + +Q S+ GD L N L+ +H + + C
Sbjct: 1217 VDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENA-----LVSEHAQRDR-CE 1270
Query: 977 HLLKIKNTFCLWKRLIKLKDNHCEQ---LRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 1033
++K +++ D H EQ L K+ +L++K L++++ H+
Sbjct: 1271 TQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQL--------VYAHK 1322
Query: 1034 ILELEKELCSLRFAIQQEKKKRRNVEEVHQKV 1065
+ K +++F E K +R++ E +++V
Sbjct: 1323 KVNKSKVTINIQF---PEMKMQRHLNEKNEEV 1351
Score = 37.7 bits (86), Expect = 0.086
Identities = 148/714 (20%), Positives = 262/714 (36%), Gaps = 101/714 (14%)
Query: 18 LEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVT 77
+E +K A K + +V N A E+K+EQ L A + + S + D
Sbjct: 522 VEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ----TLRAAQMFPSESKQKDD------E 571
Query: 78 ENEFSLES--EIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFA 135
EN + ES E +S+ + K + + +EE+ + D +P K +
Sbjct: 572 ENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESP-----VKDGLLKPTCGRKVS 626
Query: 136 LESENISEPYFTNRRTISQQSAEN---LDAACGID--------KTENGNMFEDQNVDKEG 184
L ++ + +R T +S + L CG + ++ + ++ D +G
Sbjct: 627 LPNKALE---LKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETLKAESPDNDG 683
Query: 185 KALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL-TLK 243
P G+K ++ P +KDR+ + +S +E + S L TL
Sbjct: 684 LLKPTCGRKVSL-----PNKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLL 738
Query: 244 EADPS-SKAAMRRKDSPPPGKV--SSQKQPAEKATSDDKDSVSNIATEIKE--------- 291
+ D KA +++ GK+ S K K T K S+ N A E+K+
Sbjct: 739 QNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDV 798
Query: 292 GPISGTVSSQKQP-AEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSL 350
+ T S +P E + S + + N+ T K + TV+ Q++ +I +
Sbjct: 799 SSVESTFSLFGKPTTENSQSTKVEEDFNLTT---KEGATKTVTGQQERDIGIIERAPQDQ 855
Query: 351 LNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIAT---EIKDGLQCGTVSSQKQPA 407
N G K T S+ + + L AT EIK S +K
Sbjct: 856 TNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSH 915
Query: 408 LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTD-------EKDSVSNIATEIK 460
+ T+ ++SV N E K+ + S+ L A +KD+ I +++
Sbjct: 916 FEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKME 975
Query: 461 DGE-KSGTVSSQKPPALTATSDEEGSVLSIARE--------NKDGEKSRTV-----SSRK 506
+ K + + A S E +E N++ EK R V R
Sbjct: 976 QTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIRP 1035
Query: 507 KPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEK 566
+ L+ + K R +D E+ S+ L S +S + EN +K
Sbjct: 1036 EEQLRKKLEVKQQLEQTLR-IQDIELKSVTSN-----LNQVSHTHESENDLFHENCMLKK 1089
Query: 567 SRTVSSEKPPGLKASS--------------AEKDSVLNIARGKKDGEKTKRVSSRKKPSL 612
+ + LK EK++ L + K TKR +S+ + L
Sbjct: 1090 EIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKR-ASQYREQL 1148
Query: 613 EATSDEKDSFSNITREKKDGEI-SRKVSSQKPPALKGTSDEEDSVLGIARENKD 665
+ + E ++ +EK+D EI ++ S P D + SV +R+N++
Sbjct: 1149 KVLTAENTMLTSKLKEKQDKEILETEIESHHPRLASALQDHDQSV--TSRKNQE 1200
Score = 32.0 bits (71), Expect = 4.7
Identities = 28/170 (16%), Positives = 74/170 (43%), Gaps = 17/170 (10%)
Query: 1353 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1412
+ K L + +++ + C + R L +++ + + ++ +K K C +KE +E +
Sbjct: 934 KNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKE 993
Query: 1413 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1472
QL+ ++ + + + L N ++ R+ +D ++ + + ++QL
Sbjct: 994 IKSQLENQKAKWEQELCSVRLTL-----------NQEEEKRRNVDILKEKIRP-EEQLRK 1041
Query: 1473 TIRCTKEMEGDTQKLEVEHVMMRKIIK--KQDDQIERLEKILQHSSLMLQ 1520
+ +++E Q L ++ + ++ + Q E L H + ML+
Sbjct: 1042 KLEVKQQLE---QTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLK 1088
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 249 bits (637), Expect = 1e-65
Identities = 187/574 (32%), Positives = 293/574 (51%), Gaps = 95/574 (16%)
Query: 858 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 917
RI G G P P+LK + E ++ + A + K+VQT AEQ L +ASE EQ+R
Sbjct: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
Query: 918 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 977
E E QPQV I+ + T +
Sbjct: 376 ERSEKKQPQV-------------IEGNNTYKSEK-------------------------- 396
Query: 978 LLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI--- 1034
I+L +N C + S R++++ +I +
Sbjct: 397 --------------IQLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
Query: 1035 LELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 1094
L+ E + C+L+ QE +++ NV +H+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
Query: 1095 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 1151
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
Query: 1152 IVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 1211
I K + L+K +K N E + KT Y +L L ENT L S+L K++ES+++LE E++
Sbjct: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
Query: 1212 SYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKA 1266
SY RL AA H ++ ++R+ +LA + T D ++ + L+ QLSK
Sbjct: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
Query: 1267 ESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 1325
+ K LK + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
Query: 1326 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLL 1382
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
Query: 1383 EEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQ 1416
EE NK L+NE +H KE QYE++KAE V++++
Sbjct: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 249 bits (637), Expect = 1e-65
Identities = 187/574 (32%), Positives = 293/574 (51%), Gaps = 95/574 (16%)
Query: 858 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 917
RI G G P P+LK + E ++ + A + K+VQT AEQ L +ASE EQ+R
Sbjct: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
Query: 918 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 977
E E QPQV I+ + T +
Sbjct: 376 ERSEKKQPQV-------------IEGNNTYKSEK-------------------------- 396
Query: 978 LLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI--- 1034
I+L +N C + S R++++ +I +
Sbjct: 397 --------------IQLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
Query: 1035 LELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 1094
L+ E + C+L+ QE +++ NV +H+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
Query: 1095 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 1151
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
Query: 1152 IVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 1211
I K + L+K +K N E + KT Y +L L ENT L S+L K++ES+++LE E++
Sbjct: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
Query: 1212 SYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKA 1266
SY RL AA H ++ ++R+ +LA + T D ++ + L+ QLSK
Sbjct: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
Query: 1267 ESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 1325
+ K LK + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
Query: 1326 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLL 1382
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
Query: 1383 EEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQ 1416
EE NK L+NE +H KE QYE++KAE V++++
Sbjct: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 753
Score = 235 bits (600), Expect = 2e-61
Identities = 120/120 (100%), Positives = 120/120 (100%)
Query: 20 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 79
VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN
Sbjct: 622 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 681
Query: 80 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 139
EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE
Sbjct: 682 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 741
Score = 115 bits (289), Expect = 2e-25
Identities = 66/115 (57%), Positives = 78/115 (67%)
Query: 400 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEI 459
VSSQKQPALKAT+ +EDS+SNIATEIKDG+KSGTVSSQKQPALK T+D+ DSVSN ATEI
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 460 KDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATS 514
KD +KSGTV L + +V EN+ +S +S P K S
Sbjct: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 108 bits (271), Expect = 3e-23
Identities = 62/107 (57%), Positives = 74/107 (69%)
Query: 363 SGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIA 422
S VSSQKQPA KATS K DS NIATEIKDG + GTVSSQKQPALK T+D++DSVSN A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 423 TEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVS 469
TEIKD +KSGTV + L + D+V+ TE + +S +S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIIS 691
Score = 101 bits (252), Expect = 5e-21
Identities = 55/71 (77%), Positives = 58/71 (81%)
Query: 737 SGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIA 796
S VS QKQPALKATS K+DS+SNI TEIKDGQ+SGTVSSQKQPA K TS K DSVSN A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 797 TEIKDGQIRGT 807
TEIKD Q GT
Sbjct: 645 TEIKDEQKSGT 655
Score = 99.8 bits (247), Expect = 2e-20
Identities = 56/93 (60%), Positives = 64/93 (68%)
Query: 706 VSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEI 765
VSS KQPALKA KEDS+ N+ATE KD Q SGTVS QKQPALK TSDK DSVSN TEI
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 766 KDGQQSGTVSSQKQPAWKATSVKKDSVSNIATE 798
KD Q+SGTV + + + D+V+ TE
Sbjct: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 680
Score = 99.8 bits (247), Expect = 2e-20
Identities = 54/71 (76%), Positives = 59/71 (83%)
Query: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
VSSQKQPA KATS +DS+SNIATEIK+G SGTVSSQKQPA K TSD+ DSVSN ATEI
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 324 KKGQQSGTVSP 334
K Q+SGTV P
Sbjct: 648 KDEQKSGTVLP 658
Score = 94.4 bits (233), Expect = 8e-19
Identities = 50/72 (69%), Positives = 59/72 (81%)
Query: 431 SGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIA 490
S VSSQKQPALKAT+ ++DS+SNIATEIKDG+KSGTVSSQK PAL TSD++ SV + A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 491 RENKDGEKSRTV 502
E KD +KS TV
Sbjct: 645 TEIKDEQKSGTV 656
Score = 94.0 bits (232), Expect = 1e-18
Identities = 60/143 (41%), Positives = 84/143 (58%), Gaps = 2/143 (1%)
Query: 669 SRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMA 728
S VSS+K P LKATS ++DS+ NIA KDG+K+ TVSS KQPALK DK+DSV N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 729 TEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVK 788
TE KDEQ SGTV + L + + D+V+ TE + +S +S P K S +
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704
Query: 789 KDSVSNIATEIKDGQIRGTGILE 811
S+ ++ +++ R +L+
Sbjct: 705 --SIKDVLPPVEEAVDRCLYLLD 725
Score = 85.1 bits (209), Expect = 5e-16
Identities = 54/120 (45%), Positives = 67/120 (55%)
Query: 635 SRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIA 694
S VSSQK PALK TS +EDS+ IA E KDG+KS TVSS+K P LK TSD+ DSV N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 695 RGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPALKATSDK 754
KD +K+ TV + L + D+V TE + S +S P K S +
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704
Score = 83.6 bits (205), Expect = 1e-15
Identities = 54/115 (46%), Positives = 64/115 (55%)
Query: 329 SGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATSDKTDSALNIA 388
S VS QKQ A K K+ S+ NIAT I G KSGTVSSQKQPA K TSDK DS N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 389 TEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
TEIKD + GTV + L + D+V+ TE + +S +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 82.4 bits (202), Expect = 3e-15
Identities = 53/115 (46%), Positives = 65/115 (56%)
Query: 295 SGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIA 354
S VSSQKQPA KATS ++DS+SNIATEIK GQ+SGTVS QKQ A K K S+ N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 355 TRIMGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALK 409
T I KSGTV + + + D+ TE + L+ +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 77.8 bits (190), Expect = 7e-14
Identities = 47/90 (52%), Positives = 56/90 (62%)
Query: 499 SRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 558
S VSS+K+PALKATS ++DS SNI KDG+ S VSSQK P LK TSD++DSV A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 559 RENKDGEKSRTVSSEKPPGLKASSAEKDSV 588
E KD +KS TV L S D+V
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAV 674
Score = 77.4 bits (189), Expect = 1e-13
Identities = 42/69 (60%), Positives = 52/69 (75%)
Query: 604 VSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIAREN 663
VSS+K+P+L+ATS ++DS SNI E KDG+ S VSSQK PALK TSD++DSV A E
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 664 KDGEKSRTV 672
KD +KS TV
Sbjct: 648 KDEQKSGTV 656
Score = 77.0 bits (188), Expect = 1e-13
Identities = 52/118 (44%), Positives = 65/118 (55%)
Query: 465 SGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNIT 524
S VSSQK PAL ATS +E S+ +IA E KDG+KS TVSS+K+PALK TSD+ DS SN
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 525 RGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASS 582
KD + S V L + D+V EN+ +S +S P K S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 73.2 bits (178), Expect = 2e-12
Identities = 47/118 (39%), Positives = 65/118 (55%)
Query: 567 SRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNIT 626
S VSS+K P LKA+S ++DS+ NIA KDG+K+ VSS+K+P+L+ TSD+ DS SN
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 627 REKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATS 684
E KD + S V L + D+V EN+ +S +S P K S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 71.6 bits (174), Expect = 5e-12
Identities = 47/115 (40%), Positives = 61/115 (53%)
Query: 533 SRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIA 592
S VSSQK P LK TS +EDS+ IA E KDG+KS TVSS+K P LK +S + DSV N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 593 RGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALK 647
KD +K+ V + L + D+ + E + S +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 67.0 bits (162), Expect = 1e-10
Identities = 50/122 (40%), Positives = 58/122 (47%), Gaps = 26/122 (21%)
Query: 771 SGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNK 830
S VSSQKQPA KATS K+DS+SNIATEIKDGQ GT
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGT----------------------- 621
Query: 831 SAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTA 890
VS QKQ A K K S+ N AT I KSGT P L ++ ++V
Sbjct: 622 ---VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPV 678
Query: 891 TK 892
T+
Sbjct: 679 TE 680
Score = 65.5 bits (158), Expect = 4e-10
Identities = 45/124 (36%), Positives = 61/124 (49%)
Query: 225 LTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSN 284
+ S+ SS++ P T + D S A KD G VSSQKQPA K TSD DSVSN
Sbjct: 583 INSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSN 642
Query: 285 IATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIF 344
ATEIK+ SGTV + + D+V+ TE + +S +S K+I
Sbjct: 643 TATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Query: 345 KKKV 348
+ +
Sbjct: 703 PRSI 706
Score = 61.2 bits (147), Expect = 7e-09
Identities = 58/170 (34%), Positives = 78/170 (45%), Gaps = 12/170 (7%)
Query: 742 CQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV-----SNIA 796
C+ QP L A S +K + + K + + T +KD V NI
Sbjct: 484 CEYQPLLFAVSRRKVKMVEFLLKKKANVNAIDYLGRSALIHAVTLGEKDIVILLLQHNID 543
Query: 797 TEIKDG--QIRGTGILEYTFNVMFDQIEE----KFTSLN-KSAGVSPQKQSAQKVIFKKK 849
+D +I G +E V+FD I E ++ L S VS QKQ A K K+
Sbjct: 544 VLSRDAFRKIAGDYAIEAKNRVIFDLIYEYKRKRYEDLPINSNPVSSQKQPALKATSGKE 603
Query: 850 VSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS 899
S+ NIAT I G KSGT + P LK T + +SV NTAT++KD Q S
Sbjct: 604 DSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDEQKS 653
Score = 32.0 bits (71), Expect = 4.7
Identities = 16/57 (28%), Positives = 29/57 (50%)
Query: 874 PTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQ 930
P LKAT ++S+ N AT++KD Q S + A + + + N ++K++
Sbjct: 594 PALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDE 650
>gi|169217530 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 121
Score = 224 bits (571), Expect = 5e-58
Identities = 114/116 (98%), Positives = 116/116 (100%)
Query: 1409 EREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD 1468
E++VAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD
Sbjct: 6 EKKVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD 65
Query: 1469 QLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES 1524
QLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES
Sbjct: 66 QLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES 121
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sapiens]
Length = 823
Score = 215 bits (548), Expect = 2e-55
Identities = 144/435 (33%), Positives = 245/435 (56%), Gaps = 29/435 (6%)
Query: 997 NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI---LELEKELCSLRFAIQQEKK 1053
N E++++ + +S R++++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 1054 KRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ-VSETDE 1112
++ NV +++K RE+L E+QY+ E + K ++P ++S E++ KT N N+ +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEE 506
Query: 1113 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNGET 1170
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K N E
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 1171 LAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSS 1230
+ +T Y +L L ENT L ++L K++ES++RLE +++SY RL AA H +S +
Sbjct: 567 ITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 1231 KRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALK 1285
+R+ +LA + T D ++ + L+ QLS+ + K LK + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 1286 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 1341
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 1342 QLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKEC 1401
QLDD K D++E + NIQ E K L+LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 1402 QYEKEKAEREVAVRQ 1416
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sapiens]
Length = 823
Score = 215 bits (548), Expect = 2e-55
Identities = 144/435 (33%), Positives = 245/435 (56%), Gaps = 29/435 (6%)
Query: 997 NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI---LELEKELCSLRFAIQQEKK 1053
N E++++ + +S R++++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 1054 KRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ-VSETDE 1112
++ NV +++K RE+L E+QY+ E + K ++P ++S E++ KT N N+ +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEE 506
Query: 1113 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNGET 1170
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K N E
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 1171 LAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSS 1230
+ +T Y +L L ENT L ++L K++ES++RLE +++SY RL AA H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 1231 KRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALK 1285
+R+ +LA + T D ++ + L+ QLS+ + K LK + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 1286 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 1341
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 1342 QLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKEC 1401
QLDD K D++E + NIQ E K L+LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 1402 QYEKEKAEREVAVRQ 1416
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 215 bits (548), Expect = 2e-55
Identities = 144/435 (33%), Positives = 245/435 (56%), Gaps = 29/435 (6%)
Query: 997 NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI---LELEKELCSLRFAIQQEKK 1053
N E++++ + +S R++++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 1054 KRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSN-QVSETDE 1112
++ NV +++K RE+L E+QY+ E + K ++P ++S E++ KT N N +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEE 506
Query: 1113 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNGET 1170
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K N E
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 1171 LAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSS 1230
+ +T Y +L L ENT L ++L K++ES++RLE +++SY RL AA H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 1231 KRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALK 1285
+R+ +LA + T D ++ + + L+ QLS+ + K LK + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 1286 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 1341
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 1342 QLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKEC 1401
QLDD K D++E + NIQ E K L+LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 1402 QYEKEKAEREVAVRQ 1416
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 213 bits (541), Expect = 1e-54
Identities = 143/435 (32%), Positives = 242/435 (55%), Gaps = 29/435 (6%)
Query: 997 NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEI---LELEKELCSLRFAIQQEKK 1053
N E++++ + +S R++++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 1054 KRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSN-QVSETDE 1112
++ NV +++K RE+L E+QY+ E + K ++P ++S E++ KT N N +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEE 506
Query: 1113 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNGET 1170
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K N E
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 1171 LAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSS 1230
+ +T Y +L L ENT L ++L K++ES++RLE +++SY RL AA H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 1231 KRDQELAFQGTVDKCRHLQ-----ENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALK 1285
+R+ +LA + T D ++ + L+ QLS+ + K LK + T ++L+
Sbjct: 627 ERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 1286 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 1341
+K+L E VQ+ L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 1342 QLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKEC 1401
QLDD K D++E + NIQ E K +LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDFVLEEKSKKLMNECDHLKESLF 797
Query: 1402 QYEKEKAEREVAVRQ 1416
QYE+EK E V++++
Sbjct: 798 QYEREKTEVVVSIKE 812
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 209 bits (531), Expect = 2e-53
Identities = 159/490 (32%), Positives = 268/490 (54%), Gaps = 46/490 (9%)
Query: 1047 AIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ 1106
A++ E K+R K R+KL+ +E + E + +K A + + L+ N Q
Sbjct: 372 AMKPENLKKR-------KKRKKLKKRKEGAKAEHN----LKVASEEKQERLERSENKQPQ 420
Query: 1107 VSET-DEKEDLLHENRLMQDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKA 1163
S++ +K+D + N +++ +IA L+ E IKN +L EKKY+++ + + + + +K+
Sbjct: 421 DSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKS 480
Query: 1164 LKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCD 1223
++ N E + K +A YS QL L EN L SKLEK++ +++RLE E++S H L A +
Sbjct: 481 VRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINE 540
Query: 1224 HDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------ILSLQLSKAESKSRVLKTE 1276
+++ ++D EL D RH E + S++ +L+ Q+ KA K LK +
Sbjct: 541 YNEI-LERKDLELVLWRADDVSRH--ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGK 597
Query: 1277 LHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQL 1332
L T +AL+EK L E VQ +LKQ Q ++K++++M+ +G + I KQ ER Q
Sbjct: 598 LRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQR 657
Query: 1333 KKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNE 1392
+ +N+LL++QL+DAR + DN+E ++NI C ++N + + LLEE NK L+NE
Sbjct: 658 ELENLLLERQLEDARKEGDNKE-IVINIHRDC---LENGKED------LLEERNKELMNE 707
Query: 1393 LNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDS 1452
N+ KEK QYEKEKAEREV VR+ Q++ D L K S +++ L+ +S HC + S
Sbjct: 708 YNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTS-HCHINLDETWTS 766
Query: 1453 RKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKIL 1512
+KKL Q+ Q +E ++ + ++ RK ++ +++ +K L
Sbjct: 767 KKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQI-------RKKNRELEEEATGYKKCL 819
Query: 1513 QHSSLMLQVF 1522
+ + ML F
Sbjct: 820 EMTINMLNAF 829
Score = 58.2 bits (139), Expect = 6e-08
Identities = 128/645 (19%), Positives = 265/645 (41%), Gaps = 107/645 (16%)
Query: 892 KMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 951
K+K + AE +L++ASE +Q+RLE EN QP Q SQ+ +
Sbjct: 386 KLKKRKEGAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKK 429
Query: 952 DSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKN 1011
D + N +LK ++ L + L +K++ + + I+++K+
Sbjct: 430 DEMFGN-------------------FMLK-RDIAMLKEELYAIKNDSLRKEKKYIQEIKS 469
Query: 1012 KASV---LQKRISEKEEI----KSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQK 1064
+ +K + EE+ +Q ++ +L+ E L +++EK + +E +
Sbjct: 470 ITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVES 529
Query: 1065 VREKLRITEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENR 1121
+ L +Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R
Sbjct: 530 LHSNLATAINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKAR 588
Query: 1122 LMQDEI-ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNGETL-AKTIACY 1178
+ + + +LR +D ++ + L + ++ D + + + +++ K + NGE +++I
Sbjct: 589 VKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEM-KQMHPNGEAKESQSIGKQ 647
Query: 1179 SGQLAALTD---ENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQE 1235
+ + EN L +LE R+ E + + L + + +R++E
Sbjct: 648 NSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGK----EDLLEERNKE 703
Query: 1236 LAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQ 1295
L +++ +L+E L LQ K +++ V+ E E L + F +
Sbjct: 704 L-----MNEYNYLKEKL--------LQYEKEKAEREVIVREFQ---EELVDHLKKFSMSE 747
Query: 1296 SELKQKQSQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADN 1352
S L+ ++++ + S + I EK E F ++ + LL D R K N
Sbjct: 748 SPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--N 805
Query: 1353 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1412
+E L+ E ++ LE ML N ++ + ++
Sbjct: 806 RE----------------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDI 849
Query: 1413 AVRQLQQKRDDVLNKGSATKA-----LLDASSRHCTYLENG-MQDSRKKLDQMRSQFQEI 1466
++L+QK DD++ + A + D H L G +Q+ +KL++ + +E
Sbjct: 850 LFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE- 908
Query: 1467 QDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKI 1511
+ ME D +L ++ ++ IE+LE+I
Sbjct: 909 -----KVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 948
Score = 35.0 bits (79), Expect = 0.55
Identities = 50/202 (24%), Positives = 91/202 (45%), Gaps = 26/202 (12%)
Query: 934 RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKC----KDCVHLLKIKNTFCLWK 989
+ DD++ + VS S C N ++ Q + + C L K K L +
Sbjct: 855 KQKFDDLMAEKEAVS----SKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKM--LEE 908
Query: 990 RLIKLKDNHCEQLRVKIRKLKNKASVLQKR----ISEKEEIKSQLKHEILELEKELCSL- 1044
+++ LK H E+ V++ K++ S L +R I + EEI Q + E EK+L L
Sbjct: 909 KVLNLK-THMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQ---AEYEKQLEQLN 964
Query: 1045 RFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNS 1104
+ KKK +++V K K++ E DVT ++ ++ V LK + S
Sbjct: 965 KDNTASLKKKELTLKDVECKF-SKMKTAYE------DVTTELEEYKEAFAVALKANSSMS 1017
Query: 1105 NQVSETDEKEDLLHENRLMQDE 1126
+++++D+K ++ M+ E
Sbjct: 1018 EKITKSDKKIAVISTKLFMEKE 1039
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 209 bits (531), Expect = 2e-53
Identities = 159/490 (32%), Positives = 268/490 (54%), Gaps = 46/490 (9%)
Query: 1047 AIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ 1106
A++ E K+R K R+KL+ +E + E + +K A + + L+ N Q
Sbjct: 401 AMKPENLKKR-------KKRKKLKKRKEGAKAEHN----LKVASEEKQERLERSENKQPQ 449
Query: 1107 VSET-DEKEDLLHENRLMQDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKA 1163
S++ +K+D + N +++ +IA L+ E IKN +L EKKY+++ + + + + +K+
Sbjct: 450 DSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKS 509
Query: 1164 LKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCD 1223
++ N E + K +A YS QL L EN L SKLEK++ +++RLE E++S H L A +
Sbjct: 510 VRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINE 569
Query: 1224 HDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------ILSLQLSKAESKSRVLKTE 1276
+++ ++D EL D RH E + S++ +L+ Q+ KA K LK +
Sbjct: 570 YNEI-LERKDLELVLWRADDVSRH--ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGK 626
Query: 1277 LHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQL 1332
L T +AL+EK L E VQ +LKQ Q ++K++++M+ +G + I KQ ER Q
Sbjct: 627 LRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQR 686
Query: 1333 KKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNE 1392
+ +N+LL++QL+DAR + DN+E ++NI C ++N + + LLEE NK L+NE
Sbjct: 687 ELENLLLERQLEDARKEGDNKE-IVINIHRDC---LENGKED------LLEERNKELMNE 736
Query: 1393 LNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDS 1452
N+ KEK QYEKEKAEREV VR+ Q++ D L K S +++ L+ +S HC + S
Sbjct: 737 YNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTS-HCHINLDETWTS 795
Query: 1453 RKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKIL 1512
+KKL Q+ Q +E ++ + ++ RK ++ +++ +K L
Sbjct: 796 KKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQI-------RKKNRELEEEATGYKKCL 848
Query: 1513 QHSSLMLQVF 1522
+ + ML F
Sbjct: 849 EMTINMLNAF 858
Score = 58.2 bits (139), Expect = 6e-08
Identities = 128/645 (19%), Positives = 265/645 (41%), Gaps = 107/645 (16%)
Query: 892 KMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 951
K+K + AE +L++ASE +Q+RLE EN QP Q SQ+ +
Sbjct: 415 KLKKRKEGAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKK 458
Query: 952 DSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKN 1011
D + N +LK ++ L + L +K++ + + I+++K+
Sbjct: 459 DEMFGN-------------------FMLK-RDIAMLKEELYAIKNDSLRKEKKYIQEIKS 498
Query: 1012 KASV---LQKRISEKEEI----KSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQK 1064
+ +K + EE+ +Q ++ +L+ E L +++EK + +E +
Sbjct: 499 ITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVES 558
Query: 1065 VREKLRITEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENR 1121
+ L +Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R
Sbjct: 559 LHSNLATAINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKAR 617
Query: 1122 LMQDEI-ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNGETL-AKTIACY 1178
+ + + +LR +D ++ + L + ++ D + + + +++ K + NGE +++I
Sbjct: 618 VKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEM-KQMHPNGEAKESQSIGKQ 676
Query: 1179 SGQLAALTD---ENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQE 1235
+ + EN L +LE R+ E + + L + + +R++E
Sbjct: 677 NSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGK----EDLLEERNKE 732
Query: 1236 LAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQ 1295
L +++ +L+E L LQ K +++ V+ E E L + F +
Sbjct: 733 L-----MNEYNYLKEKL--------LQYEKEKAEREVIVREFQ---EELVDHLKKFSMSE 776
Query: 1296 SELKQKQSQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADN 1352
S L+ ++++ + S + I EK E F ++ + LL D R K N
Sbjct: 777 SPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--N 834
Query: 1353 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1412
+E L+ E ++ LE ML N ++ + ++
Sbjct: 835 RE----------------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDI 878
Query: 1413 AVRQLQQKRDDVLNKGSATKA-----LLDASSRHCTYLENG-MQDSRKKLDQMRSQFQEI 1466
++L+QK DD++ + A + D H L G +Q+ +KL++ + +E
Sbjct: 879 LFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE- 937
Query: 1467 QDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKI 1511
+ ME D +L ++ ++ IE+LE+I
Sbjct: 938 -----KVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 977
Score = 35.0 bits (79), Expect = 0.55
Identities = 50/202 (24%), Positives = 91/202 (45%), Gaps = 26/202 (12%)
Query: 934 RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKC----KDCVHLLKIKNTFCLWK 989
+ DD++ + VS S C N ++ Q + + C L K K L +
Sbjct: 884 KQKFDDLMAEKEAVS----SKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKM--LEE 937
Query: 990 RLIKLKDNHCEQLRVKIRKLKNKASVLQKR----ISEKEEIKSQLKHEILELEKELCSL- 1044
+++ LK H E+ V++ K++ S L +R I + EEI Q + E EK+L L
Sbjct: 938 KVLNLK-THMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQ---AEYEKQLEQLN 993
Query: 1045 RFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNS 1104
+ KKK +++V K K++ E DVT ++ ++ V LK + S
Sbjct: 994 KDNTASLKKKELTLKDVECKF-SKMKTAYE------DVTTELEEYKEAFAVALKANSSMS 1046
Query: 1105 NQVSETDEKEDLLHENRLMQDE 1126
+++++D+K ++ M+ E
Sbjct: 1047 EKITKSDKKIAVISTKLFMEKE 1068
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 209 bits (531), Expect = 2e-53
Identities = 159/490 (32%), Positives = 268/490 (54%), Gaps = 46/490 (9%)
Query: 1047 AIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ 1106
A++ E K+R K R+KL+ +E + E + +K A + + L+ N Q
Sbjct: 401 AMKPENLKKR-------KKRKKLKKRKEGAKAEHN----LKVASEEKQERLERSENKQPQ 449
Query: 1107 VSET-DEKEDLLHENRLMQDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKA 1163
S++ +K+D + N +++ +IA L+ E IKN +L EKKY+++ + + + + +K+
Sbjct: 450 DSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKS 509
Query: 1164 LKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCD 1223
++ N E + K +A YS QL L EN L SKLEK++ +++RLE E++S H L A +
Sbjct: 510 VRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINE 569
Query: 1224 HDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------ILSLQLSKAESKSRVLKTE 1276
+++ ++D EL D RH E + S++ +L+ Q+ KA K LK +
Sbjct: 570 YNEI-LERKDLELVLWRADDVSRH--ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGK 626
Query: 1277 LHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQL 1332
L T +AL+EK L E VQ +LKQ Q ++K++++M+ +G + I KQ ER Q
Sbjct: 627 LRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQR 686
Query: 1333 KKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNE 1392
+ +N+LL++QL+DAR + DN+E ++NI C ++N + + LLEE NK L+NE
Sbjct: 687 ELENLLLERQLEDARKEGDNKE-IVINIHRDC---LENGKED------LLEERNKELMNE 736
Query: 1393 LNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDS 1452
N+ KEK QYEKEKAEREV VR+ Q++ D L K S +++ L+ +S HC + S
Sbjct: 737 YNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTS-HCHINLDETWTS 795
Query: 1453 RKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKIL 1512
+KKL Q+ Q +E ++ + ++ RK ++ +++ +K L
Sbjct: 796 KKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQI-------RKKNRELEEEATGYKKCL 848
Query: 1513 QHSSLMLQVF 1522
+ + ML F
Sbjct: 849 EMTINMLNAF 858
Score = 58.2 bits (139), Expect = 6e-08
Identities = 128/645 (19%), Positives = 265/645 (41%), Gaps = 107/645 (16%)
Query: 892 KMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 951
K+K + AE +L++ASE +Q+RLE EN QP Q SQ+ +
Sbjct: 415 KLKKRKEGAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKK 458
Query: 952 DSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKN 1011
D + N +LK ++ L + L +K++ + + I+++K+
Sbjct: 459 DEMFGN-------------------FMLK-RDIAMLKEELYAIKNDSLRKEKKYIQEIKS 498
Query: 1012 KASV---LQKRISEKEEI----KSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQK 1064
+ +K + EE+ +Q ++ +L+ E L +++EK + +E +
Sbjct: 499 ITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVES 558
Query: 1065 VREKLRITEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENR 1121
+ L +Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R
Sbjct: 559 LHSNLATAINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKAR 617
Query: 1122 LMQDEI-ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNGETL-AKTIACY 1178
+ + + +LR +D ++ + L + ++ D + + + +++ K + NGE +++I
Sbjct: 618 VKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEM-KQMHPNGEAKESQSIGKQ 676
Query: 1179 SGQLAALTD---ENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQE 1235
+ + EN L +LE R+ E + + L + + +R++E
Sbjct: 677 NSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGK----EDLLEERNKE 732
Query: 1236 LAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQ 1295
L +++ +L+E L LQ K +++ V+ E E L + F +
Sbjct: 733 L-----MNEYNYLKEKL--------LQYEKEKAEREVIVREFQ---EELVDHLKKFSMSE 776
Query: 1296 SELKQKQSQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADN 1352
S L+ ++++ + S + I EK E F ++ + LL D R K N
Sbjct: 777 SPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--N 834
Query: 1353 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1412
+E L+ E ++ LE ML N ++ + ++
Sbjct: 835 RE----------------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDI 878
Query: 1413 AVRQLQQKRDDVLNKGSATKA-----LLDASSRHCTYLENG-MQDSRKKLDQMRSQFQEI 1466
++L+QK DD++ + A + D H L G +Q+ +KL++ + +E
Sbjct: 879 LFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE- 937
Query: 1467 QDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKI 1511
+ ME D +L ++ ++ IE+LE+I
Sbjct: 938 -----KVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 977
Score = 35.0 bits (79), Expect = 0.55
Identities = 50/202 (24%), Positives = 91/202 (45%), Gaps = 26/202 (12%)
Query: 934 RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKC----KDCVHLLKIKNTFCLWK 989
+ DD++ + VS S C N ++ Q + + C L K K L +
Sbjct: 884 KQKFDDLMAEKEAVS----SKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKM--LEE 937
Query: 990 RLIKLKDNHCEQLRVKIRKLKNKASVLQKR----ISEKEEIKSQLKHEILELEKELCSL- 1044
+++ LK H E+ V++ K++ S L +R I + EEI Q + E EK+L L
Sbjct: 938 KVLNLK-THMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQ---AEYEKQLEQLN 993
Query: 1045 RFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNS 1104
+ KKK +++V K K++ E DVT ++ ++ V LK + S
Sbjct: 994 KDNTASLKKKELTLKDVECKF-SKMKTAYE------DVTTELEEYKEAFAVALKANSSMS 1046
Query: 1105 NQVSETDEKEDLLHENRLMQDE 1126
+++++D+K ++ M+ E
Sbjct: 1047 EKITKSDKKIAVISTKLFMEKE 1068
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 199 bits (506), Expect = 2e-50
Identities = 159/530 (30%), Positives = 277/530 (52%), Gaps = 37/530 (6%)
Query: 1011 NKASVLQKRISEKEEIKSQ----LKHEILELEKELCSLRFAIQQEKKK--RRNVEEVHQK 1064
N +S++ + + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 318 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 377
Query: 1065 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 1123
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 378 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 437
Query: 1124 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQ 1181
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ N + + KT+A YS Q
Sbjct: 438 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 497
Query: 1182 LAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGT 1241
L L EN L S+LEK++ +++RLE E++S H L A ++++ ++D EL
Sbjct: 498 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 556
Query: 1242 VDKCRHLQENLNSHVL-----ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQS 1296
D RH + N L +L+ Q+ KA K LK +L T +AL+EK L VQ
Sbjct: 557 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 616
Query: 1297 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 1352
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 617 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 676
Query: 1353 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1412
+E ++NI C ++N + + LLEE NK L+ E N+ KEK Q EKEKAEREV
Sbjct: 677 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 726
Query: 1413 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1472
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 727 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785
Query: 1473 TIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVF 1522
+ ++ RK ++ +++ +K L+ + ML F
Sbjct: 786 LFELISLLNYTADQI-------RKKNRELEEEATGYKKCLEMTINMLNAF 828
Score = 55.8 bits (133), Expect = 3e-07
Identities = 148/679 (21%), Positives = 256/679 (37%), Gaps = 143/679 (21%)
Query: 881 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDL--- 937
+N+ + +K + AE +L++ASE +Q+RL+ EN QPQ + D
Sbjct: 374 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYG 433
Query: 938 ------DDIIQSSQTVSEDGDSLCCNCKNV--ILLIDQHEMKCKDCVHLLKIKNTFCLWK 989
D + + + DSL K + I I + + V L + T + +
Sbjct: 434 NFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVAR 493
Query: 990 RLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLK------HEILE---LEKE 1040
+L D E R+ K K + ++ +E E + S L +EI+E LE
Sbjct: 494 YSQQLNDLKAENARLNSELEKEKHN-KERLEAEVESLHSSLATAINEYNEIVERKDLELV 552
Query: 1041 LCSLRFAIQQEK----------KKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPAL 1090
L + EK K E+VH K R K + + R D + AL
Sbjct: 553 LWRADDVSRHEKMGSNISQLTDKNELLTEQVH-KARVKFNTLKGKLRETRDALREKTLAL 611
Query: 1091 KSAEVELKTG-----------GNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKN 1139
S +++L+ N + S++ K++ L E R+ Q E+ L LE+
Sbjct: 612 GSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSL-EERIRQQELENLLLERQL--- 667
Query: 1140 QNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKL--- 1196
+K + EIV H D L+ E L + + L E L+ KL
Sbjct: 668 -EDARKEGDNKEIVINIHRD---CLENGKEDLLEE------RNKELMKEYNYLKEKLLQC 717
Query: 1197 EKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHV 1256
EK++ R+ + E Q DH ++ S E +GT +L E S
Sbjct: 718 EKEKAEREVIVREFQE-------ELVDHLKTFSI---SESPLEGTSHCHINLNETWTSKK 767
Query: 1257 LILSLQLSKAESKSRVLK-----TELHYTGEALKEKALVFEH------------------ 1293
+ +++ E K + L+YT + +++K E
Sbjct: 768 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 827
Query: 1294 -------VQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFC-QLKKQNMLLQQQLDD 1345
+L Q +M + K K +N + E C L K N +L Q+L
Sbjct: 828 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQEL-- 885
Query: 1346 ARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSK---EKEC- 1401
++N+Q +C K LE+D KML E+ + K EK+
Sbjct: 886 --------------------LSMRNVQEKCEK----LEKDKKMLEEEVLNLKTHMEKDMV 921
Query: 1402 ------QYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT----YLENGMQD 1451
+Y+ E ER AV+++++ + L K + + L+ ++ T E ++D
Sbjct: 922 ELGKLQEYKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKD 979
Query: 1452 SRKKLDQMRSQFQEIQDQL 1470
K +M++ ++E+ +L
Sbjct: 980 VECKFSKMKTAYEEVTTEL 998
Score = 37.7 bits (86), Expect = 0.086
Identities = 142/712 (19%), Positives = 273/712 (38%), Gaps = 123/712 (17%)
Query: 716 AICDKEDSVPNMATEKKDEQISGTV-------SCQKQPALKATSDKKDSVSNIPTEIKDG 768
A+C S+ E K++ + + + K LK ++ + N+ ++
Sbjct: 347 ALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEK 406
Query: 769 QQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEE-KFTS 827
Q+ S KQP + KK KD G +L+ ++ +++ K S
Sbjct: 407 QERLQRSENKQPQDSQSYGKK----------KDAMY-GNFMLKKDIAMLKEELYAIKNDS 455
Query: 828 LNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVL 887
L K + +S ++ + S+ IT K+ Y + L LKA NS L
Sbjct: 456 LRKEKKYIQEIKSITEINANFEKSVRLNEKMIT---KTVARYSQQLNDLKAENARLNSEL 512
Query: 888 NTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTV 947
K+ E ++E + EY N+I R DL+ ++ + V
Sbjct: 513 E-----KEKHNKERLEAEVESLHSSLATAINEY--------NEIVERKDLELVLWRADDV 559
Query: 948 SEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK-NTF---------CLWKRLIKLKDN 997
S N+ L D++E+ + VH ++K NT L ++ + L
Sbjct: 560 SRHEKM----GSNISQLTDKNELLTEQ-VHKARVKFNTLKGKLRETRDALREKTLALGSV 614
Query: 998 HCE--QLRVKIRKLKN--------------KASVLQKRISEKEEIKSQLKHEILELEKEL 1041
+ Q + +I+++K K + L++RI ++E L+ ++ + KE
Sbjct: 615 QLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEG 674
Query: 1042 CSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYR----IEADVTKPIKPALKSAEVEL 1097
+ I + N +E + R K + E Y ++ + K + + E
Sbjct: 675 DNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEE 734
Query: 1098 KTGGNNSNQVSETD-EKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRK 1156
+ +SE+ E H N L + ++ +L + I+ + +++ K FE++
Sbjct: 735 LVDHLKTFSISESPLEGTSHCHIN-LNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLL 793
Query: 1157 HEDLQKALKRNGET------LAKTIACYSGQLAALTDENTTLRSKLE------------- 1197
+ + K+N E K + L A +E+ + L
Sbjct: 794 NYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKL 853
Query: 1198 KQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQE------- 1250
KQ+ + E E S C +N A+ D++ H + L+ + +KC L++
Sbjct: 854 KQKFNDLVAEKEAVSSEC-VNLAK-DNEVLHQ----ELLSMRNVQEKCEKLEKDKKMLEE 907
Query: 1251 ---NLNSH-----VLILSLQLSKAESKSRVLKT-----ELHYTGEALKEKAL--VFEHVQ 1295
NL +H V + LQ K+E R ++ E+H +A EK L + +
Sbjct: 908 EVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNT 967
Query: 1296 SELKQKQSQMKDIEKMY---KSGYNTMEKCIEK-QERFCQLKKQNMLLQQQL 1343
+ LK+K+ +KD+E + K+ Y + +E+ +E F K N + ++L
Sbjct: 968 ASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKL 1019
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 199 bits (506), Expect = 2e-50
Identities = 159/530 (30%), Positives = 277/530 (52%), Gaps = 37/530 (6%)
Query: 1011 NKASVLQKRISEKEEIKSQ----LKHEILELEKELCSLRFAIQQEKKK--RRNVEEVHQK 1064
N +S++ + + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 211 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 270
Query: 1065 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 1123
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 271 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 330
Query: 1124 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQ 1181
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ N + + KT+A YS Q
Sbjct: 331 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 390
Query: 1182 LAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGT 1241
L L EN L S+LEK++ +++RLE E++S H L A ++++ ++D EL
Sbjct: 391 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 449
Query: 1242 VDKCRHLQENLNSHVL-----ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQS 1296
D RH + N L +L+ Q+ KA K LK +L T +AL+EK L VQ
Sbjct: 450 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 509
Query: 1297 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 1352
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 510 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 569
Query: 1353 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1412
+E ++NI C ++N + + LLEE NK L+ E N+ KEK Q EKEKAEREV
Sbjct: 570 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 619
Query: 1413 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1472
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 620 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 678
Query: 1473 TIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVF 1522
+ ++ RK ++ +++ +K L+ + ML F
Sbjct: 679 LFELISLLNYTADQI-------RKKNRELEEEATGYKKCLEMTINMLNAF 721
Score = 55.8 bits (133), Expect = 3e-07
Identities = 148/679 (21%), Positives = 256/679 (37%), Gaps = 143/679 (21%)
Query: 881 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDL--- 937
+N+ + +K + AE +L++ASE +Q+RL+ EN QPQ + D
Sbjct: 267 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYG 326
Query: 938 ------DDIIQSSQTVSEDGDSLCCNCKNV--ILLIDQHEMKCKDCVHLLKIKNTFCLWK 989
D + + + DSL K + I I + + V L + T + +
Sbjct: 327 NFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVAR 386
Query: 990 RLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLK------HEILE---LEKE 1040
+L D E R+ K K + ++ +E E + S L +EI+E LE
Sbjct: 387 YSQQLNDLKAENARLNSELEKEKHN-KERLEAEVESLHSSLATAINEYNEIVERKDLELV 445
Query: 1041 LCSLRFAIQQEK----------KKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPAL 1090
L + EK K E+VH K R K + + R D + AL
Sbjct: 446 LWRADDVSRHEKMGSNISQLTDKNELLTEQVH-KARVKFNTLKGKLRETRDALREKTLAL 504
Query: 1091 KSAEVELKTG-----------GNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKN 1139
S +++L+ N + S++ K++ L E R+ Q E+ L LE+
Sbjct: 505 GSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSL-EERIRQQELENLLLERQL--- 560
Query: 1140 QNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKL--- 1196
+K + EIV H D L+ E L + + L E L+ KL
Sbjct: 561 -EDARKEGDNKEIVINIHRD---CLENGKEDLLEE------RNKELMKEYNYLKEKLLQC 610
Query: 1197 EKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHV 1256
EK++ R+ + E Q DH ++ S E +GT +L E S
Sbjct: 611 EKEKAEREVIVREFQE-------ELVDHLKTFSI---SESPLEGTSHCHINLNETWTSKK 660
Query: 1257 LILSLQLSKAESKSRVLK-----TELHYTGEALKEKALVFEH------------------ 1293
+ +++ E K + L+YT + +++K E
Sbjct: 661 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 720
Query: 1294 -------VQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFC-QLKKQNMLLQQQLDD 1345
+L Q +M + K K +N + E C L K N +L Q+L
Sbjct: 721 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQEL-- 778
Query: 1346 ARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSK---EKEC- 1401
++N+Q +C K LE+D KML E+ + K EK+
Sbjct: 779 --------------------LSMRNVQEKCEK----LEKDKKMLEEEVLNLKTHMEKDMV 814
Query: 1402 ------QYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT----YLENGMQD 1451
+Y+ E ER AV+++++ + L K + + L+ ++ T E ++D
Sbjct: 815 ELGKLQEYKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKD 872
Query: 1452 SRKKLDQMRSQFQEIQDQL 1470
K +M++ ++E+ +L
Sbjct: 873 VECKFSKMKTAYEEVTTEL 891
Score = 37.7 bits (86), Expect = 0.086
Identities = 142/712 (19%), Positives = 273/712 (38%), Gaps = 123/712 (17%)
Query: 716 AICDKEDSVPNMATEKKDEQISGTV-------SCQKQPALKATSDKKDSVSNIPTEIKDG 768
A+C S+ E K++ + + + K LK ++ + N+ ++
Sbjct: 240 ALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEK 299
Query: 769 QQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEE-KFTS 827
Q+ S KQP + KK KD G +L+ ++ +++ K S
Sbjct: 300 QERLQRSENKQPQDSQSYGKK----------KDAMY-GNFMLKKDIAMLKEELYAIKNDS 348
Query: 828 LNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVL 887
L K + +S ++ + S+ IT K+ Y + L LKA NS L
Sbjct: 349 LRKEKKYIQEIKSITEINANFEKSVRLNEKMIT---KTVARYSQQLNDLKAENARLNSEL 405
Query: 888 NTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTV 947
K+ E ++E + EY N+I R DL+ ++ + V
Sbjct: 406 E-----KEKHNKERLEAEVESLHSSLATAINEY--------NEIVERKDLELVLWRADDV 452
Query: 948 SEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK-NTF---------CLWKRLIKLKDN 997
S N+ L D++E+ + VH ++K NT L ++ + L
Sbjct: 453 SRHEKM----GSNISQLTDKNELLTEQ-VHKARVKFNTLKGKLRETRDALREKTLALGSV 507
Query: 998 HCE--QLRVKIRKLKN--------------KASVLQKRISEKEEIKSQLKHEILELEKEL 1041
+ Q + +I+++K K + L++RI ++E L+ ++ + KE
Sbjct: 508 QLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEG 567
Query: 1042 CSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYR----IEADVTKPIKPALKSAEVEL 1097
+ I + N +E + R K + E Y ++ + K + + E
Sbjct: 568 DNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEE 627
Query: 1098 KTGGNNSNQVSETD-EKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRK 1156
+ +SE+ E H N L + ++ +L + I+ + +++ K FE++
Sbjct: 628 LVDHLKTFSISESPLEGTSHCHIN-LNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLL 686
Query: 1157 HEDLQKALKRNGET------LAKTIACYSGQLAALTDENTTLRSKLE------------- 1197
+ + K+N E K + L A +E+ + L
Sbjct: 687 NYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKL 746
Query: 1198 KQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQE------- 1250
KQ+ + E E S C +N A+ D++ H + L+ + +KC L++
Sbjct: 747 KQKFNDLVAEKEAVSSEC-VNLAK-DNEVLHQ----ELLSMRNVQEKCEKLEKDKKMLEE 800
Query: 1251 ---NLNSH-----VLILSLQLSKAESKSRVLKT-----ELHYTGEALKEKAL--VFEHVQ 1295
NL +H V + LQ K+E R ++ E+H +A EK L + +
Sbjct: 801 EVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNT 860
Query: 1296 SELKQKQSQMKDIEKMY---KSGYNTMEKCIEK-QERFCQLKKQNMLLQQQL 1343
+ LK+K+ +KD+E + K+ Y + +E+ +E F K N + ++L
Sbjct: 861 ASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKL 912
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 199 bits (506), Expect = 2e-50
Identities = 159/530 (30%), Positives = 277/530 (52%), Gaps = 37/530 (6%)
Query: 1011 NKASVLQKRISEKEEIKSQ----LKHEILELEKELCSLRFAIQQEKKK--RRNVEEVHQK 1064
N +S++ + + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 318 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 377
Query: 1065 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 1123
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 378 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 437
Query: 1124 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQ 1181
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ N + + KT+A YS Q
Sbjct: 438 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 497
Query: 1182 LAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGT 1241
L L EN L S+LEK++ +++RLE E++S H L A ++++ ++D EL
Sbjct: 498 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 556
Query: 1242 VDKCRHLQENLNSHVL-----ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQS 1296
D RH + N L +L+ Q+ KA K LK +L T +AL+EK L VQ
Sbjct: 557 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 616
Query: 1297 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 1352
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 617 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 676
Query: 1353 QEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREV 1412
+E ++NI C ++N + + LLEE NK L+ E N+ KEK Q EKEKAEREV
Sbjct: 677 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 726
Query: 1413 AVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1472
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 727 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785
Query: 1473 TIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVF 1522
+ ++ RK ++ +++ +K L+ + ML F
Sbjct: 786 LFELISLLNYTADQI-------RKKNRELEEEATGYKKCLEMTINMLNAF 828
Score = 55.8 bits (133), Expect = 3e-07
Identities = 148/679 (21%), Positives = 256/679 (37%), Gaps = 143/679 (21%)
Query: 881 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDL--- 937
+N+ + +K + AE +L++ASE +Q+RL+ EN QPQ + D
Sbjct: 374 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYG 433
Query: 938 ------DDIIQSSQTVSEDGDSLCCNCKNV--ILLIDQHEMKCKDCVHLLKIKNTFCLWK 989
D + + + DSL K + I I + + V L + T + +
Sbjct: 434 NFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVAR 493
Query: 990 RLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLK------HEILE---LEKE 1040
+L D E R+ K K + ++ +E E + S L +EI+E LE
Sbjct: 494 YSQQLNDLKAENARLNSELEKEKHN-KERLEAEVESLHSSLATAINEYNEIVERKDLELV 552
Query: 1041 LCSLRFAIQQEK----------KKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPAL 1090
L + EK K E+VH K R K + + R D + AL
Sbjct: 553 LWRADDVSRHEKMGSNISQLTDKNELLTEQVH-KARVKFNTLKGKLRETRDALREKTLAL 611
Query: 1091 KSAEVELKTG-----------GNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKN 1139
S +++L+ N + S++ K++ L E R+ Q E+ L LE+
Sbjct: 612 GSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSL-EERIRQQELENLLLERQL--- 667
Query: 1140 QNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKL--- 1196
+K + EIV H D L+ E L + + L E L+ KL
Sbjct: 668 -EDARKEGDNKEIVINIHRD---CLENGKEDLLEE------RNKELMKEYNYLKEKLLQC 717
Query: 1197 EKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHV 1256
EK++ R+ + E Q DH ++ S E +GT +L E S
Sbjct: 718 EKEKAEREVIVREFQE-------ELVDHLKTFSI---SESPLEGTSHCHINLNETWTSKK 767
Query: 1257 LILSLQLSKAESKSRVLK-----TELHYTGEALKEKALVFEH------------------ 1293
+ +++ E K + L+YT + +++K E
Sbjct: 768 KLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNA 827
Query: 1294 -------VQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFC-QLKKQNMLLQQQLDD 1345
+L Q +M + K K +N + E C L K N +L Q+L
Sbjct: 828 FANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQEL-- 885
Query: 1346 ARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSK---EKEC- 1401
++N+Q +C K LE+D KML E+ + K EK+
Sbjct: 886 --------------------LSMRNVQEKCEK----LEKDKKMLEEEVLNLKTHMEKDMV 921
Query: 1402 ------QYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT----YLENGMQD 1451
+Y+ E ER AV+++++ + L K + + L+ ++ T E ++D
Sbjct: 922 ELGKLQEYKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKD 979
Query: 1452 SRKKLDQMRSQFQEIQDQL 1470
K +M++ ++E+ +L
Sbjct: 980 VECKFSKMKTAYEEVTTEL 998
Score = 37.7 bits (86), Expect = 0.086
Identities = 142/712 (19%), Positives = 273/712 (38%), Gaps = 123/712 (17%)
Query: 716 AICDKEDSVPNMATEKKDEQISGTV-------SCQKQPALKATSDKKDSVSNIPTEIKDG 768
A+C S+ E K++ + + + K LK ++ + N+ ++
Sbjct: 347 ALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEK 406
Query: 769 QQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEE-KFTS 827
Q+ S KQP + KK KD G +L+ ++ +++ K S
Sbjct: 407 QERLQRSENKQPQDSQSYGKK----------KDAMY-GNFMLKKDIAMLKEELYAIKNDS 455
Query: 828 LNKSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVL 887
L K + +S ++ + S+ IT K+ Y + L LKA NS L
Sbjct: 456 LRKEKKYIQEIKSITEINANFEKSVRLNEKMIT---KTVARYSQQLNDLKAENARLNSEL 512
Query: 888 NTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTV 947
K+ E ++E + EY N+I R DL+ ++ + V
Sbjct: 513 E-----KEKHNKERLEAEVESLHSSLATAINEY--------NEIVERKDLELVLWRADDV 559
Query: 948 SEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK-NTF---------CLWKRLIKLKDN 997
S N+ L D++E+ + VH ++K NT L ++ + L
Sbjct: 560 SRHEKM----GSNISQLTDKNELLTEQ-VHKARVKFNTLKGKLRETRDALREKTLALGSV 614
Query: 998 HCE--QLRVKIRKLKN--------------KASVLQKRISEKEEIKSQLKHEILELEKEL 1041
+ Q + +I+++K K + L++RI ++E L+ ++ + KE
Sbjct: 615 QLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEG 674
Query: 1042 CSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYR----IEADVTKPIKPALKSAEVEL 1097
+ I + N +E + R K + E Y ++ + K + + E
Sbjct: 675 DNKEIVINIHRDCLENGKEDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEE 734
Query: 1098 KTGGNNSNQVSETD-EKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRK 1156
+ +SE+ E H N L + ++ +L + I+ + +++ K FE++
Sbjct: 735 LVDHLKTFSISESPLEGTSHCHIN-LNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLL 793
Query: 1157 HEDLQKALKRNGET------LAKTIACYSGQLAALTDENTTLRSKLE------------- 1197
+ + K+N E K + L A +E+ + L
Sbjct: 794 NYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKL 853
Query: 1198 KQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQE------- 1250
KQ+ + E E S C +N A+ D++ H + L+ + +KC L++
Sbjct: 854 KQKFNDLVAEKEAVSSEC-VNLAK-DNEVLHQ----ELLSMRNVQEKCEKLEKDKKMLEE 907
Query: 1251 ---NLNSH-----VLILSLQLSKAESKSRVLKT-----ELHYTGEALKEKAL--VFEHVQ 1295
NL +H V + LQ K+E R ++ E+H +A EK L + +
Sbjct: 908 EVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKDNT 967
Query: 1296 SELKQKQSQMKDIEKMY---KSGYNTMEKCIEK-QERFCQLKKQNMLLQQQL 1343
+ LK+K+ +KD+E + K+ Y + +E+ +E F K N + ++L
Sbjct: 968 ASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKANNSMSKKL 1019
>gi|239754871 PREDICTED: similar to Coiled-coil domain-containing
protein 144C [Homo sapiens]
Length = 264
Score = 124 bits (310), Expect = 9e-28
Identities = 70/174 (40%), Positives = 113/174 (64%), Gaps = 14/174 (8%)
Query: 1045 RFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNS 1104
R ++QE++KR++ + +++K E+L+ EE+Y + ++ + +K LK+ +EL+T N
Sbjct: 91 RLTLKQEEEKRKDADMLYKKGSEELKRKEEEYGKDVEINQQLKRTLKTRAMELRTVRKNL 150
Query: 1105 NQ-----------VSETDEKED-LLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDF 1150
+Q +S + +KE LLHEN ++Q+EIA LRLE DTIK+QN EKKY +D
Sbjct: 151 DQTFGNLHSLRFEISLSHKKEKGLLHENSMLQEEIAMLRLELDTIKHQNEIKEKKYFEDI 210
Query: 1151 EIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQ 1204
E VK +H++L KA+ N E LAKT+ Y+GQL+ LT EN L S+L+ + +++
Sbjct: 211 ESVKEEHDNLLKAITLNEEALAKTVFQYNGQLSILTTENKMLSSELKNVKHNKE 264
Score = 32.3 bits (72), Expect = 3.6
Identities = 29/127 (22%), Positives = 57/127 (44%), Gaps = 23/127 (18%)
Query: 1292 EHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKAD 1351
E+ + LKQ++ + KD + +YK G +++ K+E + +++ + QQL +
Sbjct: 88 EYHRLTLKQEEEKRKDADMLYKKGSEELKR---KEEEY----GKDVEINQQL---KRTLK 137
Query: 1352 NQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAERE 1411
+ + ++ D NL H L E L+H KEK +E + E
Sbjct: 138 TRAMELRTVRKNLDQTFGNL------HSLRFE-------ISLSHKKEKGLLHENSMLQEE 184
Query: 1412 VAVRQLQ 1418
+A+ +L+
Sbjct: 185 IAMLRLE 191
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.123 0.326
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,008,780
Number of Sequences: 37866
Number of extensions: 2554619
Number of successful extensions: 21407
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 260
Number of HSP's successfully gapped in prelim test: 1242
Number of HSP's that attempted gapping in prelim test: 11546
Number of HSP's gapped (non-prelim): 6580
length of query: 1524
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1409
effective length of database: 13,892,928
effective search space: 19575135552
effective search space used: 19575135552
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.