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Search of human proteins with 239741673
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
(1430 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 2765 0.0
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 2471 0.0
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 1915 0.0
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 1659 0.0
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 1253 0.0
gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 828 0.0
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 668 0.0
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 642 0.0
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 575 e-164
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 548 e-155
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 548 e-155
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 545 e-155
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 383 e-106
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 382 e-105
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 328 3e-89
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 252 2e-66
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 252 2e-66
gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 226 2e-58
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 224 4e-58
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 224 4e-58
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 224 4e-58
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 222 2e-57
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 213 8e-55
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 213 8e-55
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 213 8e-55
gi|169217530 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 209 1e-53
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 203 1e-51
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 203 1e-51
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 203 1e-51
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 129 2e-29
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 2765 bits (7168), Expect = 0.0
Identities = 1430/1430 (100%), Positives = 1430/1430 (100%)
Query: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQ 60
MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQ
Sbjct: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQ 60
Query: 61 CLNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLY 120
CLNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLY
Sbjct: 61 CLNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLY 120
Query: 121 LLDRFAQAVTKDKFALESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNV 180
LLDRFAQAVTKDKFALESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNV
Sbjct: 121 LLDRFAQAVTKDKFALESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNV 180
Query: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTL 240
DKEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTL
Sbjct: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTL 240
Query: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS
Sbjct: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
Query: 301 QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGG 360
QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGG
Sbjct: 301 QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGG 360
Query: 361 GKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
GKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN
Sbjct: 361 GKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
Query: 421 IATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATT 480
IATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATT
Sbjct: 421 IATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATT 480
Query: 481 DEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 540
DEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK
Sbjct: 481 DEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 540
Query: 541 PPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEK 600
PPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEK
Sbjct: 541 PPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEK 600
Query: 601 TRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIP 660
TRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIP
Sbjct: 601 TRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIP 660
Query: 661 TEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDE 720
TEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDE
Sbjct: 661 TEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDE 720
Query: 721 KDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLP 780
KDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLP
Sbjct: 721 KDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLP 780
Query: 781 TLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSR 840
TLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSR
Sbjct: 781 TLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSR 840
Query: 841 DDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTEL 900
DDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTEL
Sbjct: 841 DDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTEL 900
Query: 901 KDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKK 960
KDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKK
Sbjct: 901 KDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKK 960
Query: 961 RRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE 1020
RRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE
Sbjct: 961 RRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE 1020
Query: 1021 DLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAET 1080
DLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAET
Sbjct: 1021 DLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAET 1080
Query: 1081 IACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQ 1140
IACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQ
Sbjct: 1081 IACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQ 1140
Query: 1141 ELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHV 1200
ELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHV
Sbjct: 1141 ELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHV 1200
Query: 1201 QSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQE 1260
QSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQE
Sbjct: 1201 QSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQE 1260
Query: 1261 KAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAV 1320
KAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAV
Sbjct: 1261 KAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAV 1320
Query: 1321 RQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATI 1380
RQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATI
Sbjct: 1321 RQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATI 1380
Query: 1381 RCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVFES 1430
RCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVFES
Sbjct: 1381 RCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVFES 1430
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 2471 bits (6404), Expect = 0.0
Identities = 1316/1524 (86%), Positives = 1355/1524 (88%), Gaps = 94/1524 (6%)
Query: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQ 60
MVQILKNAASVFSETTSLEVSSQKQPALKDTSDK+DSVSNTATEIKDEQKSGTVLPAVEQ
Sbjct: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
Query: 61 CLNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLY 120
CLNRSLYRPDAVAQPVTE+EF+LESEIISKLYIPKRKIISPRSI+DVLPPVEEAVDRCLY
Sbjct: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
Query: 121 LLDRFAQAVTKDKFALESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNV 180
LLDRFAQ VTKDKFALESENISEPYFTNRRTISQQSAE LDAACGIDKTENG +FEDQNV
Sbjct: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
Query: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTL 240
DKEGKALPATGQKANVSPEQPPLFTHTVKD DHISTRFLG MDSLTSSEESSERPPLSTL
Sbjct: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
Query: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS
Sbjct: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
Query: 301 QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGG 360
QKQPAEKATSDEKDSVSNIATEIK+GQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI GG
Sbjct: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGG 360
Query: 361 GKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
GKSGTVSSQKQP SKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN
Sbjct: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
Query: 421 IATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATT 480
IATEIKDGEKSGTVSSQKQPALKATTDE+DSV NIATEIKDGEKS TVSSQK PAL AT+
Sbjct: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
Query: 481 DEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEI-------- 532
DEE SV IA E KDGEKS TVSSRKKPALKATSDEKDSFSNITR KKDGEI
Sbjct: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
Query: 533 --------------------------SRTVSSQKPPALKATSDEEDSVLSIAREEKDGEK 566
SRTVSS+KPP LKA+S E+DSVL+IAR +KDGEK
Sbjct: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEK 600
Query: 567 ----------------------------------SRTVSSEQPPGLKATRDEKDSLLNIA 592
SR VSS++PP LK T DE+DS+L IA
Sbjct: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
Query: 593 RGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDK 652
R K GEK+R VSS K P LKATSD+++SV N+A KD + + TVSS KQPALKA DK
Sbjct: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDK 720
Query: 653 KDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQP 712
+DSV N+ TE KD Q SGTVS QKQ A KATS KKDSVSNI TEIKDGQ GTVSSQ+QP
Sbjct: 721 EDSVPNMATEKKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQP 780
Query: 713 ALKATGDEKDSVSNIAREIKDGEKSGT--------------------------VSPQKQS 746
A KAT +KDSVSNIA EIKDG+ GT VSPQKQS
Sbjct: 781 AWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQS 840
Query: 747 AQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTST 806
AQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTST
Sbjct: 841 AQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTST 900
Query: 807 PAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKN 866
PAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKN
Sbjct: 901 PAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKN 960
Query: 867 VILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRL 926
VILLIDQHEMKCKDCVHLLKIK TFCL KRL +LKDNHCEQLRVKIRKLKNKASVLQKR+
Sbjct: 961 VILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRI 1020
Query: 927 SEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEA 986
SEKEEIKSQLKHE LELEKELCSLRFAIQQEKKKRRNVEE+HQKVREKLRITEEQYRIEA
Sbjct: 1021 SEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEA 1080
Query: 987 DVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQ 1046
DVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQ
Sbjct: 1081 DVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQ 1140
Query: 1047 NLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQR 1106
NLEKKYLKDFEIVKRKHEDLQKALKRN ETLA+TIACYSGQLAALTDENTTLRSKLEKQR
Sbjct: 1141 NLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQR 1200
Query: 1107 ESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILS 1166
ES QRLETEMQSY CRLNAA CDHDQSHSSKRDQELAFQGTVDKC HLQENLNSHVLILS
Sbjct: 1201 ESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILS 1260
Query: 1167 LQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTME 1226
LQLSKAESK RVL+TELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTME
Sbjct: 1261 LQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTME 1320
Query: 1227 KCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRL 1286
KCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARV+NLQAECRKHRL
Sbjct: 1321 KCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRL 1380
Query: 1287 LLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDASSR 1346
LLEEDNKMLVNELNHSKEK+CQYEKEKAEREVAVRQLQQK+DDVLNK SATKALLDASSR
Sbjct: 1381 LLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSR 1440
Query: 1347 HCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKK 1406
HC YLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGD QKLEVE+VMMRKIIKK
Sbjct: 1441 HCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKK 1500
Query: 1407 QDEQIERFEKILQHSSLMLQVFES 1430
QD+QIER EKILQHSSLMLQVFES
Sbjct: 1501 QDDQIERLEKILQHSSLMLQVFES 1524
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 1915 bits (4962), Expect = 0.0
Identities = 1004/1099 (91%), Positives = 1032/1099 (93%)
Query: 332 VSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEI 391
+SPQKQ A K K S+ NIAT I G SGTVSSQKQP KATSD+ DS NIATEI
Sbjct: 23 LSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
Query: 392 KDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDS 451
K+G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQKQPA K +D+ DS
Sbjct: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
Query: 452 VLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALK 511
LN ATEIKDG + TVSSQKQ ALKATTDEE SVS IATEIKDGEKSGTVSS+KKPALK
Sbjct: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
Query: 512 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVS 571
ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATS +EDSVL+IARE+KDGEKSRTVS
Sbjct: 203 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVS 262
Query: 572 SEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKD 631
EQPPGLKATRDEKDSLLNIARGKK GEKTRRVSSHKQP+LKATSDKE+SVPNMATETKD
Sbjct: 263 FEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETKD 322
Query: 632 EQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVS 691
EQISGTVS QKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ AWKATSVKKDSVS
Sbjct: 323 EQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVS 382
Query: 692 NIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI 751
NIATEIKDGQIRGTVSSQR+PALK TGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI
Sbjct: 383 NIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI 442
Query: 752 FKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQD 811
FKKKVSLLNIATRITGG KSGTEYPENL TLKATIENK+SVLNTATKMK+VQTSTPAEQD
Sbjct: 443 FKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQD 502
Query: 812 LEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLI 871
LEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLI
Sbjct: 503 LEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLI 562
Query: 872 DQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEE 931
DQHEMKCKDCVHLLKIK TFCL KRL +LKDNHCEQLRVKIRKLKNKASVLQKR+SEKEE
Sbjct: 563 DQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEE 622
Query: 932 IKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKP 991
IKSQLKHE LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKP
Sbjct: 623 IKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKP 682
Query: 992 IKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKK 1051
IKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKK
Sbjct: 683 IKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKK 742
Query: 1052 YLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQR 1111
YLKDFEIVKRKHEDLQKALKRN ETLA+TIACYSGQLAALTDENTTLRSKLEKQRES QR
Sbjct: 743 YLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQR 802
Query: 1112 LETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQLSK 1171
LETEMQSYRCRLNAA CDHDQSHSSKRDQELAFQGTVDKC HLQENLNSHVLILSLQLSK
Sbjct: 803 LETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSK 862
Query: 1172 AESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK 1231
AESK RVL+TELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK
Sbjct: 863 AESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK 922
Query: 1232 QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEED 1291
QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARV+NLQAECRKHRLLLEED
Sbjct: 923 QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEED 982
Query: 1292 NKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDASSRHCIYL 1351
NKMLVNELNHSKEK+CQYEKEKAEREVAVRQLQQK+DDVLNK SATKALLDASSRHC YL
Sbjct: 983 NKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYL 1042
Query: 1352 ENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQI 1411
ENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGD QKLEVE+VMMRKIIKKQD+QI
Sbjct: 1043 ENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQI 1102
Query: 1412 ERFEKILQHSSLMLQVFES 1430
ER EKILQHSSLMLQVFES
Sbjct: 1103 ERLEKILQHSSLMLQVFES 1121
Score = 462 bits (1189), Expect = e-129
Identities = 402/1180 (34%), Positives = 570/1180 (48%), Gaps = 172/1180 (14%)
Query: 229 EESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATE 288
E S ++ T + D S A K+ P G VSSQKQPAEKATSD+KDSVSNIATE
Sbjct: 22 ELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 81
Query: 289 IKEGPISGTVS----------------------------------SQKQPAEKATSDEKD 314
IKEG SGTVS SQKQPA K SD+ D
Sbjct: 82 IKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTD 141
Query: 315 SVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPS 374
S N ATEIK+G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQK+P
Sbjct: 142 SALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPAL 201
Query: 375 KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
KATSD+ DS NI E KDG TVSSQK PALKAT+ +EDSV NIA E KDGEKS TV
Sbjct: 202 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTV 261
Query: 435 SSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIK 494
S ++ P LKAT DE+DS+LNIA KDGEK+ VSS KQP+LKAT+D+EDSV +ATE K
Sbjct: 262 SFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATETK 321
Query: 495 DGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSV 554
D + SGTVS +K+PALKATSD+KDS SNI E KDG+ S TVSSQK PA KATS ++DSV
Sbjct: 322 DEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSV 381
Query: 555 LSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKA 614
+IA E KDG+ TVSS++ P LK T DEKDS+ NIAR K GEK+ VS KQ A K
Sbjct: 382 SNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKV 441
Query: 615 TSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSS 674
K+ S+ N+AT SGT + LKAT + KDSV N T++K+ Q S
Sbjct: 442 IFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQ 501
Query: 675 QKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDG 734
++A + + + N ++K+ + + D D + + +DG
Sbjct: 502 DLEMASEGEQKRLEEYENNQPQVKN-------------QIHSRDDLDDIIQSSQTVSEDG 548
Query: 735 EK-----SGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPEN----LPTLKAT 785
+ + Q K K V LL I WK + +N L
Sbjct: 549 DSLCCNCKNVILLIDQHEMKC--KDCVHLLKIKNTFC-LWKRLIKLKDNHCEQLRVKIRK 605
Query: 786 IENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDD 845
++NK SVL QKR+ E E + Q+K++I
Sbjct: 606 LKNKASVL--------------------------QKRISEKEEIKSQLKHEI-------- 631
Query: 846 IIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHL-LKIKKTFCLCKRLTELKDNH 904
E LC ++ I Q + K ++ L K+++ + + ++ +
Sbjct: 632 --------LELEKELC----SLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 679
Query: 905 CEQLRVKIRKLKNKASV---LQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKR 961
+ ++ ++ + + ++SE +E K L HE ++ E+ LR ++++ K
Sbjct: 680 TKPIKPALKSAEVELKTGGNNSNQVSETDE-KEDLLHENRLMQDEIARLR--LEKDTIKN 736
Query: 962 RNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSE-TDEKE 1020
+N+E+ + K E ++ R D+ K +K ++ E KT S Q++ TDE
Sbjct: 737 QNLEKKYLKDFEIVK------RKHEDLQKALK---RNGETLAKTIACYSGQLAALTDENT 787
Query: 1021 DLLHENRLMQDEIARLRLEKDTIKNQNLE---KKYLKDFEIVKRKHEDLQKALKRNEETL 1077
L R +LEK Q LE + Y + H+ + + E
Sbjct: 788 TL------------RSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAF 835
Query: 1078 AETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQ--SYRCRLNAALCDHDQS-- 1133
T+ L L +L K + L+TE+ + A + +H QS
Sbjct: 836 QGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSEL 895
Query: 1134 ---HSSKRDQELAFQ---GTVDKCCHLQE---NLNSHVLILSLQLSKAESKFRVLETELH 1184
S +D E ++ T++KC QE L ++L QL A +K E +
Sbjct: 896 KQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 955
Query: 1185 YTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQN-- 1242
+ +++Q+E ++ + +++ KM + N +E+ CQ +K+
Sbjct: 956 NIQARCDARV---QNLQAECRKHRLLLEEDNKMLVNELN------HSKEKECQYEKEKAE 1006
Query: 1243 -----MLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKH----RLLLEEDNK 1293
LQQ+ DD NK + KA+L+ +R +EN + RK R +E
Sbjct: 1007 REVAVRQLQQKRDDVLNKG-SATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD 1065
Query: 1294 MLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNK 1333
L + +KE + +K + E V +R++ +KQDD + +
Sbjct: 1066 QLTATIRCTKEMEGDTQKLEVE-HVMMRKIIKKQDDQIER 1104
Score = 377 bits (969), Expect = e-104
Identities = 357/1075 (33%), Positives = 508/1075 (47%), Gaps = 156/1075 (14%)
Query: 170 ENGTLFEDQNVDKEGKALPATGQKANVSPE----QPPLFTHTVKDSDHISTRFLGSMDSL 225
E T E +V + Q VSP+ Q +F V + I+TR +G S
Sbjct: 65 EKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLN-IATRIMGGGKSG 123
Query: 226 TSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNI 285
T S S++ P S + D + A KD G VSSQKQ A KAT+D++ SVSNI
Sbjct: 124 TVS---SQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNI 180
Query: 286 ATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFK 345
ATEIK+G SGTVSSQK+PA KATSDEKDS SNI E K+G+ S TVS QK A K
Sbjct: 181 ATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSV 240
Query: 346 KKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQ 405
K+ S+LNIA G KS TVS ++ P KAT D+ DS LNIA KDG + VSS KQ
Sbjct: 241 KEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQ 300
Query: 406 PALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKS 465
P+LKAT+D+EDSV N+ATE KD + SGTVS QKQPALKAT+D++DSV NI TEIKDG++S
Sbjct: 301 PSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQS 360
Query: 466 ETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITR 525
TVSSQKQPA KAT+ ++DSVS IATEIKDG+ GTVSS+++PALK T DEKDS SNI R
Sbjct: 361 GTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAR 420
Query: 526 EKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEK 585
E KDGE S TVS QK A K ++ S+L+IA G KS T E LKAT + K
Sbjct: 421 EIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENK 480
Query: 586 DSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQ-- 643
DS+LN A K Q + A D E MA+E + +++ ++Q Q
Sbjct: 481 DSVLNTATKMK----------EVQTSTPAEQDLE-----MASEGEQKRLEEYENNQPQVK 525
Query: 644 PALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVK-KDSVSNI--------- 693
+ + D D + + T +DG L +K KD V +
Sbjct: 526 NQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLW 585
Query: 694 --ATEIKDG---QIRGTVSSQRQPA---LKATGDEKDSVSNIAREIKDGEKS-----GTV 740
++KD Q+R + + A K ++++ S + EI + EK +
Sbjct: 586 KRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAI 645
Query: 741 SPQKQSA-------QKVIFKKKVS--LLNIATRITGGWKSGTEYPENLPTLKATIENKNS 791
+K+ QKV K +++ I +T K + E LK N N
Sbjct: 646 QQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQ 703
Query: 792 VLNTATK---------MKDVQTSTPAEQDLEMASEGEQKRLEEYE--------------- 827
V T K M+D E+D E+K L+++E
Sbjct: 704 VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKR 763
Query: 828 NNQPQVK------NQIHSRDD--------LDDIIQSSQTVSEDGDSLCCNCKNVILLIDQ 873
N + K Q+ + D L+ +S Q + + S C DQ
Sbjct: 764 NGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQ 823
Query: 874 HEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ-------KRL 926
+D L + T C+ L E ++H L +++ K ++K+ VL+ + L
Sbjct: 824 SHSSKRD--QELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEAL 881
Query: 927 SEK----EEIKSQLK--------------------HETLELEKELCSLR---FAIQQEKK 959
EK E ++S+LK + +E ++ C L+ +QQ+
Sbjct: 882 KEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLD 941
Query: 960 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEK 1019
RN + +K I Q R +A V K + + N+++ + EK
Sbjct: 942 DARNKADNQEKA-----ILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEK 996
Query: 1020 EDLLHENRLMQDEIA--RLRLEKDTIKNQNLEKKYLKD------------FEIVKRKHED 1065
E +E + E+A +L+ ++D + N+ K L D + ++K +
Sbjct: 997 E-CQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQ 1055
Query: 1066 LQKALKRNEETLAETIAC---YSGQLAALTDENTTLRSKLEKQRESGQRLETEMQ 1117
++ + ++ L TI C G L E+ +R ++KQ + +RLE +Q
Sbjct: 1056 MRSQFQEIQDQLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQ 1110
Score = 238 bits (606), Expect = 4e-62
Identities = 286/1066 (26%), Positives = 451/1066 (42%), Gaps = 140/1066 (13%)
Query: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQC 61
V +L A + S VSSQKQPA K SDK DS NTATEIKD + GTV +Q
Sbjct: 107 VSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQA 166
Query: 62 LNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYL 121
L + +V+ TE + +S +S P K S + E D
Sbjct: 167 LKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEK-DSFSNITREKKD----- 220
Query: 122 LDRFAQAVTKDK-FALESENISEPYFTN----------RRTISQQSAEKLDAACGIDKTE 170
++ V+ K AL++ ++ E N RT+S + L A + E
Sbjct: 221 -GEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKAT----RDE 275
Query: 171 NGTLFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEE 230
+L K+G+ + VS + P T D + + D S
Sbjct: 276 KDSLLNIARGKKDGE------KTRRVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTV 329
Query: 231 SSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIK 290
S ++ P T + D S KD G VSSQKQPA KATS KDSVSNIATEIK
Sbjct: 330 SCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIK 389
Query: 291 EGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSL 350
+G I GTVSSQ++PA K T DEKDSVSNIA EIK+G++SGTVSPQKQSA KVIFKKKVSL
Sbjct: 390 DGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSL 449
Query: 351 LNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKD---------GLQCGTVS 401
LNIATRITGGGKSGT + KAT + DS LN AT++K+ L+ +
Sbjct: 450 LNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEG 509
Query: 402 SQK--------QPALK----ATTDEEDSVSNIATEIKDGEK-----SGTVSSQKQPALKA 444
QK QP +K + D +D + + T +DG+ + Q +K
Sbjct: 510 EQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKC 569
Query: 445 TTDEEDSV--LNIAT---------EIKDGE------KSETVSSQKQPALKATTDEEDSVS 487
+D V L I ++KD K + ++ K +++E+ S
Sbjct: 570 ----KDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKS 625
Query: 488 IIATEIKDGEKS-----GTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPP 542
+ EI + EK + KK + + ++ I V+ P
Sbjct: 626 QLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKP 685
Query: 543 ALKA------TSDEEDSVLSIAREEKD-GEKSRTVSSEQPPGLKATRDEKDSLLNIARGK 595
ALK+ T + +S E++D ++R + E + R EKD++ N K
Sbjct: 686 ALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDE----IARLRLEKDTIKNQNLEK 741
Query: 596 KY---GEKTRRVSSHKQPALKATSDKE------NSVPNMATETKDEQISGTVSSQKQPAL 646
KY E +R Q ALK + S A ++ + + Q++
Sbjct: 742 KYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQ 801
Query: 647 KATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVK-KDSVSNIATEIKDGQIRGT 705
+ ++ + + D QS + ++LA++ T K + N+ + + ++ +
Sbjct: 802 RLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLS 861
Query: 706 VSSQRQPALKA----TGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNI 761
+ + LK TG+ + + ++ K QKQS K I K S N
Sbjct: 862 KAESKSRVLKTELHYTGEALKEKALVFEHVQSELK------QKQSQMKDIEKMYKSGYNT 915
Query: 762 ATRITGGWKSGTEYPENLPTLKATIEN-KNSVLNTATKMKDVQTSTPAEQDLEMASEGEQ 820
+ + + + L+ +++ +N N + ++Q A + +E +
Sbjct: 916 MEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQ-NLQAECRK 974
Query: 821 KRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKD 880
RL E+N+ V HS++ + Q E + + + Q + K D
Sbjct: 975 HRLLLEEDNKMLVNELNHSKE------KECQYEKEKAER--------EVAVRQLQQKRDD 1020
Query: 881 CVHLLKIKKTFCLCKRLTELKDNHCEQL-------RVKIRKLKNKASVLQKRLSEKEEIK 933
++ K T K L + HC L R K+ +++++ +Q +L+
Sbjct: 1021 VLN--KGSAT----KALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCT 1074
Query: 934 SQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITE 979
+++ +T +LE E +R I+++ + +E++ Q L++ E
Sbjct: 1075 KEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFE 1120
Score = 125 bits (314), Expect = 3e-28
Identities = 186/830 (22%), Positives = 332/830 (40%), Gaps = 150/830 (18%)
Query: 701 QIRGTVSSQRQPALKATGDEK----------------------------------DSVSN 726
++R +S Q+Q A KAT D+K DSVSN
Sbjct: 18 RLRIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 77
Query: 727 IAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATI 786
IA EIK+G++SGTVSPQKQSAQKVIFKKKVSLLNIATRI GG KSGT + P K
Sbjct: 78 IATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTAS 137
Query: 787 ENKNSVLNTATKMKD-VQTSTPAEQDLEMA-----SEG-------EQKRLEEYENNQPQV 833
+ +S LNTAT++KD +Q T + Q + EG E K E+ Q
Sbjct: 138 DKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQK 197
Query: 834 KNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKK---- 889
K + + D D + +DG+ + +K +++ + KK
Sbjct: 198 KPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEK 257
Query: 890 ----TFCLCKRLTELKDNHCEQLRV--------KIRKLKNKASVLQKRLSEKEEIKSQLK 937
+F L +D L + K R++ + K S+KE+ +
Sbjct: 258 SRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMA 317
Query: 938 HETLELE---KELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKP 994
ET + + C + A++ K+ +V + ++++ + V+ +P
Sbjct: 318 TETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQ--------SGTVSSQKQP 369
Query: 995 ALKSAEVELKTGGNNSNQVSE-------TDEKEDLLHENRLMQDEIARLRLE-KDTIKNQ 1046
A K+ V+ + N + ++ + + ++ L +D ++ + E KD K+
Sbjct: 370 AWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSG 429
Query: 1047 NLEKKYLKDFEIVKRKHEDLQKALKR-------------NEETLAETIACYSGQLAALT- 1092
+ + +++ +K L R N TL TI L T
Sbjct: 430 TVSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATK 489
Query: 1093 ----DENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTV 1148
+T LE E Q+ E ++ + ++ + D + + +
Sbjct: 490 MKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGD 549
Query: 1149 DKCCHLQENLNSHVLILS---------LQLSKAESKF----RVLETELHYTGEALKEKAL 1195
CC N + +L++ + L K ++ F R+++ + ++ E L+ K
Sbjct: 550 SLCC----NCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHC-EQLRVKIR 604
Query: 1196 VFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNK 1255
++ S L+++ S+ ++I+ K + +E ++ C L+ +QQ+ RN
Sbjct: 605 KLKNKASVLQKRISEKEEIKSQLK------HEILELEKELCSLR---FAIQQEKKKRRNV 655
Query: 1256 ADNQEKA-----ILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKK-CQY 1309
+ +K I Q R +A V K + + N+++ + EK+ +
Sbjct: 656 EELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLH 715
Query: 1310 EKEKAEREVAVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQF 1369
E + E+A +L+ ++D + N+ K L D + ++K + ++
Sbjct: 716 ENRLMQDEIA--RLRLEKDTIKNQNLEKKYLKD------------FEIVKRKHEDLQKAL 761
Query: 1370 QEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQ 1419
+ + L TI C G L EN +R ++KQ E +R E +Q
Sbjct: 762 KRNGETLAKTIAC---YSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 808
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 1659 bits (4296), Expect = 0.0
Identities = 850/862 (98%), Positives = 856/862 (99%)
Query: 569 TVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATE 628
+VSSE+P GLKAT DEKDS+LNIARGKK+GEKTRRVSSHKQPALKATSDKENSVPNMATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 629 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKD 688
TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ AWKATSVKKD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 689 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 748
SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 749 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 808
KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
Query: 809 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 868
EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 306
Query: 869 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE 928
LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE
Sbjct: 307 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE 366
Query: 929 KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 988
KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV
Sbjct: 367 KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 426
Query: 989 TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL 1048
TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL
Sbjct: 427 TKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNL 486
Query: 1049 EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRES 1108
EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRES
Sbjct: 487 EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRES 546
Query: 1109 GQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQ 1168
GQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQ
Sbjct: 547 GQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQ 606
Query: 1169 LSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 1228
LSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC
Sbjct: 607 LSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKC 666
Query: 1229 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 1288
IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL
Sbjct: 667 IEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 726
Query: 1289 EEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDASSRHC 1348
EEDNKMLVNEL HSKEK+CQYEKEKAEREVAVRQLQQK+DDVLNK SATKALLDASSRHC
Sbjct: 727 EEDNKMLVNELTHSKEKECQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHC 786
Query: 1349 IYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQD 1408
YLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQD
Sbjct: 787 TYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQD 846
Query: 1409 EQIERFEKILQHSSLMLQVFES 1430
EQIERFEKILQHSSLMLQVFES
Sbjct: 847 EQIERFEKILQHSSLMLQVFES 868
Score = 266 bits (680), Expect = 1e-70
Identities = 279/951 (29%), Positives = 422/951 (44%), Gaps = 141/951 (14%)
Query: 399 TVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATE 458
+VSS+K LKAT+DE+DSV NIA K GEK+ VSS KQPALKAT+D+E+SV N+ATE
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 459 IKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKD 518
KD + S TVSSQKQPALKAT+D++DSVS I TEIKDG++SGTVSS+K+PA KATS +KD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 519 SFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGL 578
S SNI E KDG+I TVSSQ+ PALKAT DE+DSV +IARE KDGEKS TVS ++
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 579 KATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTV 638
K +K SLLNIA G K+ P LKAT + +NSV N AT+ KD Q S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPA 246
Query: 639 SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIK 698
+ A + + + N ++K+ S +D + +I
Sbjct: 247 EQDLEMASEGEQKRLEEYENNQPQVKNQIHS-----------------RDDLDDII---- 285
Query: 699 DGQIRGTVSSQRQPALKATGDEK-DSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVS 757
Q + GD + N+ I E K + KK
Sbjct: 286 ----------QSSQTVSEDGDSLCCNCKNVILLIDQHEMK-----CKDCVHLLKIKKTFC 330
Query: 758 LLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEM--- 814
L T + + E L ++NK SVL K+ S + LE+
Sbjct: 331 LCKRLTELK------DNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKE 384
Query: 815 ------ASEGEQKRLEEYENNQPQVKNQIHSRDD-----------LDDIIQSSQTVSEDG 857
A + E+K+ E +V+ ++ ++ + ++S++ + G
Sbjct: 385 LCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTG 444
Query: 858 DSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTE--LKDNHCEQLRVK-IRK 914
N N + D+ E D +H ++ + RL + +K+ + E+ +K
Sbjct: 445 G----NNSNQVSETDEKE----DLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEI 496
Query: 915 LKNKASVLQKRLSEKEEIKSQ----LKHETLELEKELCSLRFAIQQEKKKRRNVEELHQK 970
+K K LQK L EE ++ + L E +LR ++++++ + +E Q
Sbjct: 497 VKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQS 556
Query: 971 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQ 1030
R R+ A + + + EL G T +K L EN
Sbjct: 557 YR---------CRLNAALCDHDQSHSSKRDQELAFQG--------TVDKCCHLQENLNSH 599
Query: 1031 DEIARLRLEKDTIKNQNLEKKYLKDFEIVKRK---HEDLQKALKRNEETLAETIACYSGQ 1087
I L+L K K + LE + E +K K E +Q LK+ + + + Y
Sbjct: 600 VLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSG 659
Query: 1088 LAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 1147
T+ +EKQ Q + M + D + + +QE A
Sbjct: 660 Y-------NTMEKCIEKQERFCQLKKQNMLLQQ--------QLDDARNKADNQEKAILNI 704
Query: 1148 VDKCCHLQENLNS----HVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSE 1203
+C ENL + H L+L E ++L EL ++ E KE E + E
Sbjct: 705 QARCDARVENLQAECRKHRLLL-------EEDNKMLVNELTHSKE--KECQYEKEKAERE 755
Query: 1204 LKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAI 1263
+ +Q Q K + + K + + ++ R C L+ + D+R K D
Sbjct: 756 VAVRQLQQKRDDVLNKG--SATKALLDASSRHC------TYLENGMQDSRKKLDQMRSQF 807
Query: 1264 LNIQARCDARV---ENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEK 1311
IQ + A + + ++ + +K LE +N M+ + E+ ++EK
Sbjct: 808 QEIQDQLTATIRCTKEMEGDAQK----LEVENVMMRKIIKKQDEQIERFEK 854
Score = 266 bits (679), Expect = 1e-70
Identities = 276/921 (29%), Positives = 419/921 (45%), Gaps = 138/921 (14%)
Query: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
VSS+K KATSD+KDSV NIA K G + VSS KQPA KATSD+++SV N+ATE
Sbjct: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
Query: 324 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDS 383
K+ Q SGTVS QKQ A K KK S+ NI T I G +SGTVSSQKQP KATS K DS
Sbjct: 68 KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDS 127
Query: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
NIATEIKDG GTVSSQ+QPALKAT DE+DSVSNIA EIKDGEKSGTVS QKQ A K
Sbjct: 128 VSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQK 187
Query: 444 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 503
++ S+LNIAT I G KS T + P LKAT + ++SV AT++KD + S
Sbjct: 188 VIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAE 247
Query: 504 SRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKD 563
+ A + + + N + K+ SR D+ D ++
Sbjct: 248 QDLEMASEGEQKRLEEYENNQPQVKNQIHSR--------------DDLDDII-------- 285
Query: 564 GEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVP 623
+ S+TVS + G + K+ +L I + + + + K K +
Sbjct: 286 -QSSQTVSED---GDSLCCNCKNVILLIDQHEMKCKDCVHLLKIK---------KTFCLC 332
Query: 624 NMATETKD---EQISGTVSSQKQPA---LKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ 677
TE KD EQ+ + K A K S+K+ EIK + T+ +K+
Sbjct: 333 KRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKE--------EIKSQLKHETLELEKE 384
Query: 678 L-----AWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIK 732
L A + K+ +V + ++++ ++R T R A T K ++ + E+K
Sbjct: 385 LCSLRFAIQQEKKKRRNVEELHQKVRE-KLRITEEQYRIEA-DVTKPIKPALKSAEVELK 442
Query: 733 DGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSV 792
G + + + ++ + ++ IA L K TI+N+N
Sbjct: 443 TGGNNSNQVSETDEKEDLLHENRLMQDEIA---------------RLRLEKDTIKNQNL- 486
Query: 793 LNTATKMKDVQTSTPAEQDLEMASEGEQKRLEE----YENNQPQVKNQIHS-RDDLDDII 847
+KD + +DL+ A + ++ L E Y + ++ + R L+
Sbjct: 487 --EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQR 544
Query: 848 QSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQ 907
+S Q + + S C + DQ +D L + T C L E ++H
Sbjct: 545 ESGQRLETEMQSYRCRLNAALCDHDQSHSSKRD--QELAFQGTVDKCCHLQENLNSHVLI 602
Query: 908 LRVKIRKLKNKASVLQ-------KRLSEK----EEIKSQLK------------------- 937
L +++ K ++K VL+ + L EK E ++S+LK
Sbjct: 603 LSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNT 662
Query: 938 -HETLELEKELCSLR---FAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIK 993
+ +E ++ C L+ +QQ+ RN + +K I Q R +A V
Sbjct: 663 MEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKA-----ILNIQARCDARVENLQA 717
Query: 994 PALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIA--RLRLEKDTIKNQNLEKK 1051
K + + N+++ + EKE +E + E+A +L+ ++D + N+ K
Sbjct: 718 ECRKHRLLLEEDNKMLVNELTHSKEKE-CQYEKEKAEREVAVRQLQQKRDDVLNKGSATK 776
Query: 1052 YLKD------------FEIVKRKHEDLQKALKRNEETLAETIAC---YSGQLAALTDENT 1096
L D + ++K + ++ + ++ L TI C G L EN
Sbjct: 777 ALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENV 836
Query: 1097 TLRSKLEKQRESGQRLETEMQ 1117
+R ++KQ E +R E +Q
Sbjct: 837 MMRKIIKKQDEQIERFEKILQ 857
Score = 205 bits (521), Expect = 3e-52
Identities = 230/863 (26%), Positives = 369/863 (42%), Gaps = 105/863 (12%)
Query: 191 GQKAN-VSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSS 249
G+K VS + P T + + + D S SS++ P T + D S
Sbjct: 36 GEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVS 95
Query: 250 KAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKAT 309
KD G VSSQKQPA KATS KDSVSNIATEIK+G I GTVSSQ+QPA KAT
Sbjct: 96 NIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKAT 155
Query: 310 SDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQ 369
DEKDSVSNIA EIK+G++SGTVSPQKQSA KVIFKKKVSLLNIATRITGG KSGT +
Sbjct: 156 GDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPE 215
Query: 370 KQPPSKATSDKTDSALNIATEIKD---------GLQCGTVSSQK--------QPALK--- 409
P KAT + +S LN AT++KD L+ + QK QP +K
Sbjct: 216 NLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQI 275
Query: 410 -ATTDEEDSVSNIATEIKDGEK-----SGTVSSQKQPALKA-------TTDEEDSVLNIA 456
+ D +D + + T +DG+ + Q +K + +
Sbjct: 276 HSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRL 335
Query: 457 TEIKDGE------KSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKS-----GTVSSR 505
TE+KD K + ++ K +++E+ S + E + EK +
Sbjct: 336 TELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQE 395
Query: 506 KKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKA------TSDEEDSVLSIAR 559
KK + + ++ I V+ PALK+ T + +S
Sbjct: 396 KKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETD 455
Query: 560 EEKD-GEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDK 618
E++D ++R + E + R EKD++ N KKY + V + KA
Sbjct: 456 EKEDLLHENRLMQDE----IARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRN 511
Query: 619 ENSVPN---------MATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQS 669
E ++ A ++ + + Q++ + ++ + + + D QS
Sbjct: 512 EETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQS 571
Query: 670 GTVSSQKQLAWKATSVKKDSVS---NIATEIKDGQIRGTVSSQR--QPALKATGDEKDSV 724
+ ++LA++ T K + N I Q+ S R + L TG+
Sbjct: 572 HSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEK 631
Query: 725 SNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKA 784
+ + ++ K QKQS K I K S N + + + + L+
Sbjct: 632 ALVFEHVQSELK------QKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQ 685
Query: 785 TIEN-KNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDL 843
+++ +N N + ++Q A + + +E + RL E+N+ V HS++
Sbjct: 686 QLDDARNKADNQEKAILNIQARCDARVE-NLQAECRKHRLLLEEDNKMLVNELTHSKE-- 742
Query: 844 DDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDN 903
+ Q E + + + Q + K D ++ K T K L +
Sbjct: 743 ----KECQYEKEKAER--------EVAVRQLQQKRDDVLN--KGSAT----KALLDASSR 784
Query: 904 HCEQL-------RVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQ 956
HC L R K+ +++++ +Q +L+ +++ + +LE E +R I++
Sbjct: 785 HCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKK 844
Query: 957 EKKKRRNVEELHQKVREKLRITE 979
+ ++ E++ Q L++ E
Sbjct: 845 QDEQIERFEKILQHSSLMLQVFE 867
Score = 196 bits (499), Expect = 1e-49
Identities = 229/909 (25%), Positives = 393/909 (43%), Gaps = 99/909 (10%)
Query: 195 NVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMR 254
+VS E+P T + D + G + SS + P T + + A
Sbjct: 7 SVSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATE 66
Query: 255 RKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKD 314
KD G VSSQKQPA KATSD KDSVSNI TEIK+G SGTVSSQKQPA KATS +KD
Sbjct: 67 TKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKD 126
Query: 315 SVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPS 374
SVSNIATEIK+GQ GTVS Q+Q A K +K S+ NIA I G KSGTVS QKQ
Sbjct: 127 SVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQ 186
Query: 375 KATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTV 434
K K S LNIAT I G + GT + P LKAT + ++SV N AT++KD + S
Sbjct: 187 KVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTS--- 243
Query: 435 SSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIK 494
T E+D + E K E+ E Q + + + D +D + T +
Sbjct: 244 ----------TPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSE 293
Query: 495 DGEKSGTVSSRKKPALKATSDE---KDSFSNITREKKDGEISRTVSSQKP---PALKATS 548
DG+ + K L E KD ++ + KK + + ++ K L+
Sbjct: 294 DGD--SLCCNCKNVILLIDQHEMKCKDCV-HLLKIKKTFCLCKRLTELKDNHCEQLRVKI 350
Query: 549 DEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHK 608
+ + S+ +++ EK S + L+ ++ I + KK +
Sbjct: 351 RKLKNKASVL-QKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKV 409
Query: 609 QPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQ 668
+ L+ T ++ +I V+ +PALK+ + + N ++ + +
Sbjct: 410 REKLRITEEQ-------------YRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDE 456
Query: 669 SGTVSSQKQLAWKATS---VKKDSVSNIATE---IKDGQIRGTVSSQRQPALKATGDE-K 721
+ + +L + ++KD++ N E +KD +I Q ALK +
Sbjct: 457 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLA 516
Query: 722 DSVSNIAREIKDGEKSGT-----VSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYP 776
++++ + ++ T + Q++S Q++ + + + + +S +
Sbjct: 517 ETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKR 576
Query: 777 ENLPTLKATI-------ENKNS-VLNTATKMKDVQTS-TPAEQDLEMASEGEQKRLEEYE 827
+ + T+ EN NS VL + ++ ++ E +L E +++ +E
Sbjct: 577 DQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFE 636
Query: 828 NNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKI 887
+ Q ++K + D++ + +S E KC ++
Sbjct: 637 HVQSELKQKQSQMKDIEKMYKSGYNTME---------------------KC------IEK 669
Query: 888 KKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEK-EEIKSQLKHETLELEKE 946
++ FC K+ L + R K + +Q R + E ++++ + L LE++
Sbjct: 670 QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEED 729
Query: 947 LCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIE-----ADVTKPIKPALKSAEV 1001
L + K+K E+ +K ++ + + Q + + TK + A
Sbjct: 730 NKMLVNELTHSKEKECQYEK--EKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCT 787
Query: 1002 ELKTGGNNSNQVSETDEKEDLLHENRLMQDEI-ARLRLEKDTIKN-QNLEKKYLKDFEIV 1059
L+ G +S + + D+ E +QD++ A +R K+ + Q LE + + +I+
Sbjct: 788 YLENGMQDSRK--KLDQMRSQFQE---IQDQLTATIRCTKEMEGDAQKLEVENVMMRKII 842
Query: 1060 KRKHEDLQK 1068
K++ E +++
Sbjct: 843 KKQDEQIER 851
Score = 61.6 bits (148), Expect = 5e-09
Identities = 36/71 (50%), Positives = 42/71 (59%)
Query: 8 AASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLY 67
A E S VSSQKQPALK TSDK DSVSN TEIKD Q+SGTV + +
Sbjct: 64 ATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV 123
Query: 68 RPDAVAQPVTE 78
+ D+V+ TE
Sbjct: 124 KKDSVSNIATE 134
Score = 59.3 bits (142), Expect = 3e-08
Identities = 38/96 (39%), Positives = 54/96 (56%), Gaps = 2/96 (2%)
Query: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTED 79
VSS KQPALK TSDK +SV N ATE KDEQ SGTV + L + + D+V+ TE
Sbjct: 42 VSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEI 101
Query: 80 EFALESEIISKLYIPKRKIISPR--SIEDVLPPVEE 113
+ +S +S P K S + S+ ++ +++
Sbjct: 102 KDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKD 137
Score = 54.3 bits (129), Expect = 8e-07
Identities = 27/37 (72%), Positives = 30/37 (81%)
Query: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLP 56
VSSQ+QPALK T D+ DSVSN A EIKD +KSGTV P
Sbjct: 144 VSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSP 180
Score = 52.8 bits (125), Expect = 2e-06
Identities = 35/85 (41%), Positives = 46/85 (54%)
Query: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTED 79
VSSQKQPA K TS K DSVSN ATEIKD Q GTV + L + D+V+ E
Sbjct: 110 VSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREI 169
Query: 80 EFALESEIISKLYIPKRKIISPRSI 104
+ +S +S +K+I + +
Sbjct: 170 KDGEKSGTVSPQKQSAQKVIFKKKV 194
Score = 46.2 bits (108), Expect = 2e-04
Identities = 64/305 (20%), Positives = 110/305 (36%), Gaps = 40/305 (13%)
Query: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTED 79
VSS+K LK TSD+ DSV N A K +K+ V + L + + ++V TE
Sbjct: 8 VSSEKPSGLKATSDEKDSVLNIARGKKHGEKTRRVSSHKQPALKATSDKENSVPNMATET 67
Query: 80 EFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYLLDRFAQAVTKDKFALESE 139
+ S +S P K S + D + T+ K +S
Sbjct: 68 KDEQISGTVSSQKQPALKATSDKK-------------------DSVSNIPTEIKDGQQSG 108
Query: 140 NISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNVDKEGKALPATGQKANVSPE 199
+S + ++ + ++ K D+ I T +D + + VS +
Sbjct: 109 TVS----SQKQPAWKATSVKKDSVSNI-----ATEIKDGQI------------RGTVSSQ 147
Query: 200 QPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSP 259
+ P T + D +S D S S ++ + K+ A R
Sbjct: 148 RQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGW 207
Query: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
G + P KAT ++K+SV N AT++K+ S + A + + N
Sbjct: 208 KSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENN 267
Query: 320 ATEIK 324
++K
Sbjct: 268 QPQVK 272
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 1253 bits (3242), Expect = 0.0
Identities = 684/872 (78%), Positives = 735/872 (84%), Gaps = 17/872 (1%)
Query: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQ 60
MVQILKNAASVFSETTSLEVSSQKQPALKDTSDK+DSVSNTATEIKDEQKSGTVLPAVEQ
Sbjct: 1 MVQILKNAASVFSETTSLEVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQ 60
Query: 61 CLNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLY 120
CLNRSLYRPDAVAQPVTE+EF+LESEIISKLYIPKRKIISPRSI+DVLPPVEEAVDRCLY
Sbjct: 61 CLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLY 120
Query: 121 LLDRFAQAVTKDKFALESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNV 180
LLDRFAQ VTKDKFALESENISEPYFTNRRTISQQSAE LDAACGIDKTENG +FEDQNV
Sbjct: 121 LLDRFAQPVTKDKFALESENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNV 180
Query: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTL 240
DKEGKALPATGQKANVSPEQPPLFTHTVKD DHISTRFLG MDSLTSSEESSERPPLSTL
Sbjct: 181 DKEGKALPATGQKANVSPEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTL 240
Query: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS
Sbjct: 241 TLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSS 300
Query: 301 QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGG 360
QKQPAEKATSDEKDSVSNIATEIK+GQQSGTVSPQKQSA KVIFKKKVSLLNIATRI GG
Sbjct: 301 QKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGG 360
Query: 361 GKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
GKSGTVSSQKQP SKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN
Sbjct: 361 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 420
Query: 421 IATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATT 480
IATEIKDGEKSGTVSSQKQPALKATTDE+DSV NIATEIKDGEKS TVSSQK PAL AT+
Sbjct: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
Query: 481 DEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 540
DEE SV IA E KDGEKS TVSSRKKPA KATSDEKDSFSNITR KKDGEISR VSSQK
Sbjct: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQK 540
Query: 541 PPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEK 600
PP LK TSDEEDSVL IARE KDGEKSRTVSSE+PPGLKA+ DEKDS+LNIARGKKYGEK
Sbjct: 541 PPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEK 600
Query: 601 TRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIP 660
T+RVSS K+P+L+ATSD+++S N+ E KD +IS VSSQK PALK TSD++DSV I
Sbjct: 601 TKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIA 660
Query: 661 TEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDE 720
E KDG++S TVSS+K KATS +KDSV NIA KDG+ TVSSQ+ P LKAT DE
Sbjct: 661 RENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPPTLKATSDE 720
Query: 721 KDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLP 780
+DSV +IARE KDGEKS TVS +K S K +K S+LNIA G K+ P
Sbjct: 721 EDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKYGEKTKRVSSRKKP 780
Query: 781 TLKATIENKNSVLNTATKMKDVQTSTPAEQDLE---------------MASEGEQKRLEE 825
LKAT + K+SVL A + KD + S + MA+E + +++
Sbjct: 781 ALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISG 840
Query: 826 YENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 857
++Q Q + + D D + + T +DG
Sbjct: 841 TVSSQKQ--PALKATSDKKDSVSNIPTEIKDG 870
Score = 369 bits (947), Expect = e-101
Identities = 270/638 (42%), Positives = 346/638 (54%), Gaps = 40/638 (6%)
Query: 263 KVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 322
+VSSQKQPA K TSD DSVSN ATEIK+ SGTV + + D+V+ TE
Sbjct: 19 EVSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 78
Query: 323 IKEGQQSGTVSPQKQSAWKVIFKKKVS---------------LLNIATRITGGGKSGTVS 367
+ +S +S K+I + + LL+ + K S
Sbjct: 79 NEFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALES 138
Query: 368 SQKQPP--------SKATSDKTDSALNI-ATEI----------KDGL------QCGTVSS 402
P S+ +++ D+A I TE K+G Q VS
Sbjct: 139 ENISEPYFTNRRTISQQSAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSP 198
Query: 403 QKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDG 462
++ P T + D +S D S SS++ P T E D A KD
Sbjct: 199 EQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDS 258
Query: 463 EKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSN 522
VSSQKQPA KAT+D++DSVS IATEIK+G SGTVSS+K+PA KATSDEKDS SN
Sbjct: 259 PPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 318
Query: 523 ITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATR 582
I E K G+ S TVS QK A K ++ S+L+IA G KS TVSS++ P KAT
Sbjct: 319 IATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKATS 378
Query: 583 DEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQK 642
D+ DS LNIA K G + VSS KQPALKAT+D+E+SV N+ATE KD + SGTVSSQK
Sbjct: 379 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 438
Query: 643 QPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQI 702
QPALKAT+D+KDSVSNI TEIKDG++SGTVSSQK A ATS ++ SV +IA E KDG+
Sbjct: 439 QPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEK 498
Query: 703 RGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIA 762
TVSS+++PA KAT DEKDS SNI R KDGE S VS QK K ++ S+L IA
Sbjct: 499 SRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 558
Query: 763 TRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKR 822
G KS T E P LKA+ + K+SVLN A K + + + + E
Sbjct: 559 RENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDE 618
Query: 823 LEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 860
+ + N + K+ SR + + S++ DS+
Sbjct: 619 KDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 656
Score = 59.3 bits (142), Expect = 3e-08
Identities = 32/43 (74%), Positives = 33/43 (76%)
Query: 14 ETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLP 56
E S VSSQKQPALK TSDK DSVSN TEIKD Q+SGTV P
Sbjct: 836 EQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSP 878
Score = 58.9 bits (141), Expect = 3e-08
Identities = 37/88 (42%), Positives = 49/88 (55%)
Query: 17 SLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPV 76
S VSSQKQPALK DK DSV N ATE KDEQ SGTV + L + + D+V+
Sbjct: 805 SRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIP 864
Query: 77 TEDEFALESEIISKLYIPKRKIISPRSI 104
TE + +S +S +K+I + +
Sbjct: 865 TEIKDGQQSGTVSPQKQSAQKVIFKKKV 892
>gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 475
Score = 828 bits (2140), Expect = 0.0
Identities = 421/443 (95%), Positives = 432/443 (97%)
Query: 880 DCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE 939
DCVHLLKIK TFCL KRL +LKDNHCEQLRVKIRKLKNKASVLQKR+SEKEEIKSQLKHE
Sbjct: 24 DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 83
Query: 940 TLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA 999
LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA
Sbjct: 84 ILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA 143
Query: 1000 EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIV 1059
EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRL+ DTIKNQNLEKKYLKDFEIV
Sbjct: 144 EVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLDTDTIKNQNLEKKYLKDFEIV 203
Query: 1060 KRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSY 1119
KRKHEDLQKALKRN ETLA+TIACYSGQLAALTDENTTLRSKLEKQRES QRLETEMQSY
Sbjct: 204 KRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSY 263
Query: 1120 RCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVL 1179
CRLNAA CDHDQSHSSKRDQELAFQGTVDKC HLQENLNSHVLILSLQLSKAESK RVL
Sbjct: 264 HCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVL 323
Query: 1180 ETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK 1239
+TELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK
Sbjct: 324 KTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLK 383
Query: 1240 KQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNEL 1299
KQNMLLQQQLDDARNKADNQEKAILNIQARCDARV+NLQAECRKHRLLLEEDNKMLVNEL
Sbjct: 384 KQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLEEDNKMLVNEL 443
Query: 1300 NHSKEKKCQYEKEKAEREVAVRQ 1322
NHSKEK+CQYEKEKAEREV++++
Sbjct: 444 NHSKEKECQYEKEKAEREVSIKK 466
Score = 36.6 bits (83), Expect = 0.18
Identities = 45/213 (21%), Positives = 89/213 (41%), Gaps = 14/213 (6%)
Query: 1214 IEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDAR 1273
I K+ ++ EK+E QLK + + L+++L R ++K N++
Sbjct: 56 IRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKV 115
Query: 1274 VENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQ-------YEKEKAEREVAVRQLQQK 1326
E L+ ++R+ E D + S E + + E E+E + + +
Sbjct: 116 REKLRITEEQYRI--EADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLM 173
Query: 1327 QDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEM 1386
QD++ R T + + + YL++ + ++K + ++ + + L TI C
Sbjct: 174 QDEIARLRLDTDTIKNQNLEKK-YLKD-FEIVKRKHEDLQKALKRNGETLAKTIAC---Y 228
Query: 1387 EGDAQKLEVENVMMRKIIKKQDEQIERFEKILQ 1419
G L EN +R ++KQ E +R E +Q
Sbjct: 229 SGQLAALTDENTTLRSKLEKQRESRQRLETEMQ 261
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 668 bits (1723), Expect = 0.0
Identities = 383/572 (66%), Positives = 426/572 (74%), Gaps = 34/572 (5%)
Query: 298 VSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRI 357
+S QKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSA KVIFKKKVSLLNIATRI
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 358 TGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDS 417
GGGKSGTVSSQKQP SK SDKTDSALN ATEIKDGLQCGTVSSQKQ ALKATTDEE S
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 418 VSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALK 477
VSNIATEIKDGEKSGTVSSQK+PALKAT+DE+DS NI E KDGE S TVSSQK PALK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 478 ATTDEEDSVSIIATEIKDGEKSGTVS---------------------------------- 503
AT+ +EDSV IA E KDGEKS TVS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 504 SRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKD 563
SRKKPALKATSDEKDSFSNITR KKDGEISR VSSQKPP LK TSDEEDSVL IARE KD
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 564 GEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVP 623
GEKSRTVSSE+PPGLKA+ DEKDS+LNIARGKKYGEKT+RVSS K+P+L+ATSD+++S
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 624 NMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKAT 683
N+ E KD +IS VSSQK PALK TSD++DSV I E KDG++S TVSS+K KAT
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
Query: 684 SVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQ 743
S +KDSV NIA KDG+ TVSS+++PALKAT DEKDSV IARE KDGEKS TVS Q
Sbjct: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
Query: 744 KQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQ 803
KQ A K I K+ S+ N+AT SGT + P LKAT + K+SV N T++KD Q
Sbjct: 572 KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 631
Query: 804 TSTPAEQDLEMASEGEQKRLEEYENNQPQVKN 835
S + A + + + N ++K+
Sbjct: 632 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKD 663
Score = 625 bits (1613), Expect = e-179
Identities = 378/608 (62%), Positives = 421/608 (69%), Gaps = 42/608 (6%)
Query: 170 ENGTLFEDQNVDKEGKALPATGQKANVSPE----QPPLFTHTVKDSDHISTRFLGSMDSL 225
E T E +V + Q VSP+ Q +F V + I+TR +G S
Sbjct: 100 EKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLN-IATRIMGGGKSG 158
Query: 226 TSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNI 285
T S S++ P S + D + A KD G VSSQKQ A KAT+D++ SVSNI
Sbjct: 159 TVS---SQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNI 215
Query: 286 ATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFK 345
ATEIK+G SGTVSSQK+PA KATSDEKDS SNI E K+G+ S TVS QK A K
Sbjct: 216 ATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSV 275
Query: 346 KKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQ 405
K+ S+LNIA G KS TVS + P KAT D+ DS LNIA K+G + VSS+K+
Sbjct: 276 KEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVSSRKK 335
Query: 406 PALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKS 465
PALKAT+DE+DS SNI KDGE S VSSQK P LK T+DEEDSVL IA E KDGEKS
Sbjct: 336 PALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKS 395
Query: 466 ETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITR 525
TVSS+K P LKA++DE+DSV IA K GEK+ VSSRKKP+L+ATSDEKDSFSNITR
Sbjct: 396 RTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITR 455
Query: 526 EKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEK 585
EKKDGEISR VSSQKPPALK TSDEEDSVL IARE KDGEKSRTVSSE+PPGLKAT DEK
Sbjct: 456 EKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEK 515
Query: 586 DSLLNIARGKKYGEKTRRVSSHKQPALKATS----------------------------- 616
DS+LNIARGKK GEKTR VSS K+PALKATS
Sbjct: 516 DSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPA 575
Query: 617 -----DKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGT 671
DKE+SVPNMATE KDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGT
Sbjct: 576 LKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGT 635
Query: 672 VSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREI 731
VSSQKQ AWKATSVKKDSVSNIATEIKDGQIRGTVS Q+Q A K +K S+ NIA I
Sbjct: 636 VSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATRI 695
Query: 732 KDGEKSGT 739
G KSGT
Sbjct: 696 TGGGKSGT 703
Score = 486 bits (1251), Expect = e-137
Identities = 295/541 (54%), Positives = 358/541 (66%), Gaps = 17/541 (3%)
Query: 332 VSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEI 391
+SPQKQ A K +K S+ NIAT I G +SGTVS QKQ K K S LNIAT I
Sbjct: 92 MSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRI 151
Query: 392 KDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDS 451
G + GTVSSQKQPA K +D+ DS N ATEIKDG + GTVSSQKQ ALKATTDEE S
Sbjct: 152 MGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTVSSQKQQALKATTDEEGS 211
Query: 452 VLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALK 511
V NIATEIKDGEKS TVSSQK+PALKAT+DE+DS S I E KDGE S TVSS+K PALK
Sbjct: 212 VSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 271
Query: 512 ATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVS 571
ATS ++DS NI REKKDGE SRTVS +PP LKAT DE+DS+L+IAR +K+GEK+R VS
Sbjct: 272 ATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEKTRRVS 331
Query: 572 SEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKD 631
S + P LKAT DEKDS NI RGKK GE +R+VSS K P LK TSD+E+SV +A E KD
Sbjct: 332 SRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKD 391
Query: 632 EQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVS 691
+ S TVSS+K P LKA+SD+KDSV NI K G+++ VSS+K+ + +ATS +KDS S
Sbjct: 392 GEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFS 451
Query: 692 NIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVI 751
NI E KDG+I VSSQ+ PALK T DE+DSV IARE KDGEKS TVS +K K
Sbjct: 452 NITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKAT 511
Query: 752 FKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQD 811
+K S+LNIA G K+ T P LKAT + K+SVL A + KD + S
Sbjct: 512 SDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ 571
Query: 812 LE---------------MASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSED 856
+ MA+E + +++ ++Q Q + + D D + + T +D
Sbjct: 572 KQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQ--PALKATSDKKDSVSNIPTEIKD 629
Query: 857 G 857
G
Sbjct: 630 G 630
Score = 459 bits (1180), Expect = e-128
Identities = 309/677 (45%), Positives = 386/677 (57%), Gaps = 46/677 (6%)
Query: 1 MVQILKNAASVFSETT------SLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTV 54
++ +L++ VFS +S QKQPA K TSD+ DSVSN ATEIK+ Q+SGTV
Sbjct: 67 VILLLQHNIDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTV 126
Query: 55 LPAVEQCLNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEA 114
P + + ++ T +S +S P K S ++
Sbjct: 127 SPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKT----------- 175
Query: 115 VDRCLYLLDRFAQAVTKDKFALESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTL 174
D T+ K L+ T+S Q + L A + + +
Sbjct: 176 --------DSALNTATEIKDGLQC-----------GTVSSQKQQALKATTDEEGSVSNIA 216
Query: 175 FEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSER 234
E ++ +K G VS ++ P T + D S D S SS++
Sbjct: 217 TEIKDGEKSG----------TVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQK 266
Query: 235 PPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPI 294
PP T + D A +KD VS + P KAT D+KDS+ NIA K G
Sbjct: 267 PPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKNGEK 326
Query: 295 SGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIA 354
+ VSS+K+PA KATSDEKDS SNI K+G+ S VS QK K ++ S+L IA
Sbjct: 327 TRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIA 386
Query: 355 TRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDE 414
G KS TVSS+K P KA+SD+ DS LNIA K G + VSS+K+P+L+AT+DE
Sbjct: 387 RENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDE 446
Query: 415 EDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQP 474
+DS SNI E KDGE S VSSQK PALK T+DEEDSVL IA E KDGEKS TVSS+K P
Sbjct: 447 KDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPP 506
Query: 475 ALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISR 534
LKAT+DE+DSV IA KDGEK+ TVSSRKKPALKATSDEKDS I REKKDGE SR
Sbjct: 507 GLKATSDEKDSVLNIARGKKDGEKTRTVSSRKKPALKATSDEKDSVLYIAREKKDGEKSR 566
Query: 535 TVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARG 594
TVSSQK PALKA D+EDSV ++A E+KD + S TVSS++ P LKAT D+KDS+ NI
Sbjct: 567 TVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTE 626
Query: 595 KKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKD 654
K G+++ VSS KQPA KATS K++SV N+ATE KD QI GTVS QKQ A K KK
Sbjct: 627 IKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKV 686
Query: 655 SVSNIPTEIKDGQQSGT 671
S+ NI T I G +SGT
Sbjct: 687 SLLNIATRITGGGKSGT 703
Score = 287 bits (734), Expect = 6e-77
Identities = 201/470 (42%), Positives = 268/470 (57%), Gaps = 9/470 (1%)
Query: 400 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVL-----N 454
+ ++ QP L A + + + + K + + L T E+D V+ N
Sbjct: 15 ILNEYQPLLLAVSRRKVKMVEFLLKKKANVNAIDYLGRSALILAVTLGEKDIVILLLQHN 74
Query: 455 IATEIKD--GEKSE--TVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPAL 510
I +D G+ +E +S QKQPA KAT+DE+DSVS IATEIK+G++SGTVS +K+ A
Sbjct: 75 IDVFSRDVYGKLAEDYAMSPQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAQ 134
Query: 511 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTV 570
K +K S NI G S TVSSQK PA K SD+ DS L+ A E KDG + TV
Sbjct: 135 KVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSALNTATEIKDGLQCGTV 194
Query: 571 SSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETK 630
SS++ LKAT DE+ S+ NIA K GEK+ VSS K+PALKATSD+++S N+ E K
Sbjct: 195 SSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKK 254
Query: 631 DEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSV 690
D +IS TVSSQK PALKATS K+DSV NI E KDG++S TVS + KAT +KDS+
Sbjct: 255 DGEISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSL 314
Query: 691 SNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKV 750
NIA K+G+ VSS+++PALKAT DEKDS SNI R KDGE S VS QK K
Sbjct: 315 LNIARGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKG 374
Query: 751 IFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQ 810
++ S+L IA G KS T E P LKA+ + K+SVLN A K + +
Sbjct: 375 TSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSS 434
Query: 811 DLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 860
+ + E + + N + K+ SR + + S++ DS+
Sbjct: 435 RKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEEDSV 484
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 642 bits (1656), Expect = 0.0
Identities = 343/384 (89%), Positives = 358/384 (93%)
Query: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI
Sbjct: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
Query: 324 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDS 383
KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQP SKATSDKTDS
Sbjct: 68 KEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDS 127
Query: 384 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK
Sbjct: 128 ALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 187
Query: 444 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 503
ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS
Sbjct: 188 ATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVS 247
Query: 504 SRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKD 563
SRKKPALKATSDEKDSFSNITREKKDGEISRTV+S+KP LKATSDEEDSVL+IAR ++D
Sbjct: 248 SRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKED 307
Query: 564 GEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVP 623
GEK+R VSS + P LKAT DEKDS NI R KK GE +R VSS K PALKATSD+E+SV
Sbjct: 308 GEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVL 367
Query: 624 NMATETKDEQISGTVSSQKQPALK 647
++A E KD + S TVSS++ P LK
Sbjct: 368 SIAREEKDGEKSRTVSSEQPPGLK 391
Score = 486 bits (1251), Expect = e-137
Identities = 274/384 (71%), Positives = 309/384 (80%)
Query: 293 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLN 352
P +VSSQKQPAEKATSD+KDSVSNIATEIKEG SGTVS QKQ A K +K S+ N
Sbjct: 3 PFCFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSN 62
Query: 353 IATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATT 412
IAT I G +SGTVS QKQ K K S LNIAT I G + GTVSSQKQPA KAT+
Sbjct: 63 IATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATS 122
Query: 413 DEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQK 472
D+ DS NIATEIKDG + GTVSSQKQPALKATTDEEDSV NIATEIKDGEKS TVSSQK
Sbjct: 123 DKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQK 182
Query: 473 QPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEI 532
QPALKATTDEEDSV IATEIKDGEKS TVSS+K+PALKAT+DE+DS S I E KDGE
Sbjct: 183 QPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEK 242
Query: 533 SRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIA 592
S TVSS+K PALKATSDE+DS +I RE+KDGE SRTV+SE+P GLKAT DE+DS+LNIA
Sbjct: 243 SGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIA 302
Query: 593 RGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDK 652
RGK+ GEKTRRVSS K+PALKATSD+++S N+ E KD + S TVSSQK PALKATSD+
Sbjct: 303 RGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDE 362
Query: 653 KDSVSNIPTEIKDGQQSGTVSSQK 676
+DSV +I E KDG++S TVSS++
Sbjct: 363 EDSVLSIAREEKDGEKSRTVSSEQ 386
Score = 439 bits (1129), Expect = e-123
Identities = 250/387 (64%), Positives = 298/387 (77%)
Query: 365 TVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATE 424
+VSSQKQP KATSD DS NIATEIK+G GTVSSQKQPA KAT+DE+DSVSNIATE
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 425 IKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEED 484
IK+G++SGTVS QKQ A K ++ S+LNIAT I G KS TVSSQKQPA KAT+D+ D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 485 SVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPAL 544
S IATEIKDG + GTVSS+K+PALKAT+DE+DS SNI E KDGE S TVSSQK PAL
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 545 KATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRV 604
KAT+DEEDSVL+IA E KDGEKS TVSS++ P LKAT DE+DS+ IA K GEK+ V
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 605 SSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIK 664
SS K+PALKATSD+++S N+ E KD +IS TV+S+K LKATSD++DSV NI +
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 665 DGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSV 724
DG+++ VSS+K+ A KATS +KDS SNI E KDG+ TVSSQ+ PALKAT DE+DSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 725 SNIAREIKDGEKSGTVSPQKQSAQKVI 751
+IARE KDGEKS TVS ++ KV+
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLKVM 393
Score = 438 bits (1126), Expect = e-122
Identities = 255/385 (66%), Positives = 289/385 (75%)
Query: 331 TVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATE 390
+VS QKQ A K K S+ NIAT I G SGTVSSQKQP KATSD+ DS NIATE
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 391 IKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEED 450
IK+G Q GTVS QKQ A K ++ S+ NIAT I G KSGTVSSQKQPA KAT+D+ D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 451 SVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPAL 510
S LNIATEIKDG + TVSSQKQPALKATTDEEDSVS IATEIKDGEKSGTVSS+K+PAL
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 511 KATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTV 570
KAT+DE+DS NI E KDGE S TVSSQK PALKAT+DEEDSV IA E KDGEKS TV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 571 SSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETK 630
SS + P LKAT DEKDS NI R KK GE +R V+S K LKATSD+E+SV N+A +
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 631 DEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSV 690
D + + VSS+K+PALKATSD+KDS SNI E KDG+ S TVSSQK A KATS ++DSV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 691 SNIATEIKDGQIRGTVSSQRQPALK 715
+IA E KDG+ TVSS++ P LK
Sbjct: 367 LSIAREEKDGEKSRTVSSEQPPGLK 391
Score = 415 bits (1066), Expect = e-115
Identities = 243/387 (62%), Positives = 288/387 (74%)
Query: 397 CGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIA 456
C +VSSQKQPA KAT+D++DSVSNIATEIK+G SGTVSSQKQPA KAT+DE+DSV NIA
Sbjct: 5 CFSVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIA 64
Query: 457 TEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDE 516
TEIK+G++S TVS QKQ A K ++ S+ IAT I G KSGTVSS+K+PA KATSD+
Sbjct: 65 TEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDK 124
Query: 517 KDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPP 576
DS NI E KDG TVSSQK PALKAT+DEEDSV +IA E KDGEKS TVSS++ P
Sbjct: 125 TDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQP 184
Query: 577 GLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISG 636
LKAT DE+DS+LNIA K GEK+ VSS KQPALKAT+D+E+SV +ATE KD + SG
Sbjct: 185 ALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSG 244
Query: 637 TVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATE 696
TVSS+K+PALKATSD+KDS SNI E KDG+ S TV+S+K KATS ++DSV NIA
Sbjct: 245 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARG 304
Query: 697 IKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKV 756
+DG+ VSS+++PALKAT DEKDS SNI RE KDGE S TVS QK A K ++
Sbjct: 305 KEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEED 364
Query: 757 SLLNIATRITGGWKSGTEYPENLPTLK 783
S+L+IA G KS T E P LK
Sbjct: 365 SVLSIAREEKDGEKSRTVSSEQPPGLK 391
Score = 371 bits (952), Expect = e-102
Identities = 219/373 (58%), Positives = 270/373 (72%)
Query: 433 TVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATE 492
+VSSQKQPA KAT+D++DSV NIATEIK+G S TVSSQKQPA KAT+DE+DSVS IATE
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 493 IKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEED 552
IK+G++SGTVS +K+ A K +K S NI G S TVSSQK PA KATSD+ D
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 553 SVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPAL 612
S L+IA E KDG + TVSS++ P LKAT DE+DS+ NIA K GEK+ VSS KQPAL
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 613 KATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTV 672
KAT+D+E+SV N+ATE KD + S TVSSQKQPALKAT+D++DSVS I TEIKDG++SGTV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 673 SSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIK 732
SS+K+ A KATS +KDS SNI E KDG+I TV+S++ LKAT DE+DSV NIAR +
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 733 DGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSV 792
DGEK+ VS +K+ A K +K S NI G S T + P LKAT + ++SV
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Query: 793 LNTATKMKDVQTS 805
L+ A + KD + S
Sbjct: 367 LSIAREEKDGEKS 379
Score = 308 bits (789), Expect = 2e-83
Identities = 191/360 (53%), Positives = 238/360 (66%)
Query: 501 TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIARE 560
+VSS+K+PA KATSD+KDS SNI E K+G IS TVSSQK PA KATSDE+DSV +IA E
Sbjct: 7 SVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 66
Query: 561 EKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKEN 620
K+G++S TVS ++ K +K SLLNIA G K+ VSS KQPA KATSDK +
Sbjct: 67 IKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPASKATSDKTD 126
Query: 621 SVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAW 680
S N+ATE KD GTVSSQKQPALKAT+D++DSVSNI TEIKDG++SGTVSSQKQ A
Sbjct: 127 SALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPAL 186
Query: 681 KATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTV 740
KAT+ ++DSV NIATEIKDG+ TVSSQ+QPALKAT DE+DSVS IA EIKDGEKSGTV
Sbjct: 187 KATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTV 246
Query: 741 SPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMK 800
S +K+ A K +K S NI G S T E LKAT + ++SVLN A +
Sbjct: 247 SSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKE 306
Query: 801 DVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSL 860
D + + + A + + + N + K+ SR + + S++ DS+
Sbjct: 307 DGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSV 366
Score = 262 bits (669), Expect = 2e-69
Identities = 157/287 (54%), Positives = 188/287 (65%)
Query: 191 GQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSK 250
G+ VS ++ P T +D D L SS++ P T E D S
Sbjct: 105 GKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN 164
Query: 251 AAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATS 310
A KD G VSSQKQPA KAT+D++DSV NIATEIK+G S TVSSQKQPA KAT+
Sbjct: 165 IATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATT 224
Query: 311 DEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQK 370
DE+DSVS IATEIK+G++SGTVS +K+ A K +K S NI G S TV+S+K
Sbjct: 225 DEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEK 284
Query: 371 QPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEK 430
KATSD+ DS LNIA +DG + VSS+K+PALKAT+DE+DS SNI E KDGE
Sbjct: 285 PAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGET 344
Query: 431 SGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALK 477
S TVSSQK PALKAT+DEEDSVL+IA E KDGEKS TVSS++ P LK
Sbjct: 345 SRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK 391
Score = 240 bits (612), Expect = 8e-63
Identities = 175/424 (41%), Positives = 226/424 (53%), Gaps = 40/424 (9%)
Query: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTED 79
VSSQKQPA K TSD DSVSN ATEIK+ SGTV + + D+V+ TE
Sbjct: 8 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 67
Query: 80 EFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYLLDRFAQAVTKDKFALESE 139
+ +S +S K+I + + T+ +S
Sbjct: 68 KEGQQSGTVSPQKQSAWKVIFKKKVS-------------------LLNIATRITGGGKSG 108
Query: 140 NISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNVDKEGKALPATGQKANVSPE 199
+S + ++ S+ +++K D+A I TE K+G Q VS +
Sbjct: 109 TVS----SQKQPASKATSDKTDSALNI-ATE----------IKDGL------QCGTVSSQ 147
Query: 200 QPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSP 259
+ P T + D +S D S SS++ P T E D A KD
Sbjct: 148 KQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGE 207
Query: 260 PPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNI 319
VSSQKQPA KAT+D++DSVS IATEIK+G SGTVSS+K+PA KATSDEKDS SNI
Sbjct: 208 KSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNI 267
Query: 320 ATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSD 379
E K+G+ S TV+ +K + K ++ S+LNIA G K+ VSS+K+P KATSD
Sbjct: 268 TREKKDGEISRTVTSEKPAGLKATSDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSD 327
Query: 380 KTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQ 439
+ DS NI E KDG TVSSQK PALKAT+DEEDSV +IA E KDGEKS TVSS++
Sbjct: 328 EKDSFSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQP 387
Query: 440 PALK 443
P LK
Sbjct: 388 PGLK 391
Score = 140 bits (353), Expect = 9e-33
Identities = 116/342 (33%), Positives = 155/342 (45%), Gaps = 40/342 (11%)
Query: 2 VQILKNAASVFSETTSLEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQC 61
V +L A + S VSSQKQPA K TSDK DS N ATEIKD + GTV +
Sbjct: 92 VSLLNIATRITGGGKSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPA 151
Query: 62 LNRSLYRPDAVAQPVTEDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYL 121
L + D+V+ TE + +S +S P K +
Sbjct: 152 LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE------------------ 193
Query: 122 LDRFAQAVTKDKFALESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNVD 181
D T+ K +SE T+S Q L A + + + E ++ +
Sbjct: 194 -DSVLNIATEIKDGEKSE-----------TVSSQKQPALKATTDEEDSVSIIATEIKDGE 241
Query: 182 KEGKALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLT 241
K G VS + P T + D S D S +SE+P T
Sbjct: 242 KSG----------TVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVTSEKPAGLKAT 291
Query: 242 LKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQ 301
E D A ++D +VSS+K+PA KATSD+KDS SNI E K+G S TVSSQ
Sbjct: 292 SDEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDSFSNITREKKDGETSRTVSSQ 351
Query: 302 KQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVI 343
K PA KATSDE+DSV +IA E K+G++S TVS ++ KV+
Sbjct: 352 KPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKVM 393
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 575 bits (1483), Expect = e-164
Identities = 350/849 (41%), Positives = 507/849 (59%), Gaps = 77/849 (9%)
Query: 639 SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSN---IAT 695
S ++ LK T + KDSV N +KD Q S ++A + ++ S +N +
Sbjct: 489 SPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSENNQPQVEE 548
Query: 696 EIKDGQIRGT-VSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKK 754
E K + VS+ ++ D + ++ K GE P+K++ +
Sbjct: 549 ERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKENKEYASSGP 608
Query: 755 KVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEM 814
+ + + + + E + ++ + + K S+L D +S L
Sbjct: 609 ALQMKEVKS-------TEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSS------LSE 655
Query: 815 ASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQH 874
E E + ++ N + +VKNQI S DD+DD+ QSS+T SED + + KN +LLI+Q
Sbjct: 656 IDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQL 715
Query: 875 EMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKS 934
M+CKD V LLKI+ C+RL ELK NHCE L VKI+K+++K +VLQ+ LSE +EIKS
Sbjct: 716 GMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKS 775
Query: 935 QLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKP 994
QL+H+ +E E+ELCSLRF++ QE++KRRN + L++K+RE+LR EEQYR E +V + ++
Sbjct: 776 QLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLEL 835
Query: 995 ALKSAEVELKTGGNNSNQVSET-------------------------------------- 1016
+L++ E+EL+T +N NQV +
Sbjct: 836 SLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKK 895
Query: 1017 ---------DEKEDLLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDFEIVKRKHED 1065
+E++DL H+N ++Q+EIA LRLE DTIKNQN EKK +D +IVK K+ED
Sbjct: 896 MNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNED 955
Query: 1066 LQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNA 1125
LQK +K+NEETL +TI+ Y+G+L+ LT EN L SKLE +++S +RLE E++SY RL A
Sbjct: 956 LQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAA 1015
Query: 1126 ALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVL-------ILSLQLSKAESKFRV 1178
A+ D DQS +SKR+ ELAFQ D+C LQ+ +N V ILS QL K ESK
Sbjct: 1016 AIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNS 1075
Query: 1179 LETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ER 1234
LE E H+T +AL+EK L E VQ +L Q Q QMK++E+ Y++ + K I KQ ER
Sbjct: 1076 LEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEER 1135
Query: 1235 FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKM 1294
QL+ +NMLL+QQLDDA NKADN+EK ++NIQ + A V+ LQAE K LLLEE NK
Sbjct: 1136 LSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKE 1195
Query: 1295 LVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENG 1354
L++E NH KE++ QYE EKAEREV VRQLQQ+ D L K+S ++A L+ +SR+ I LE+
Sbjct: 1196 LISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDE 1255
Query: 1355 MQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERF 1414
QD +KKL Q+R+Q QE QD+ T +RC ++M+ QKLE +N ++ +KKQ ++IE
Sbjct: 1256 TQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEEL 1315
Query: 1415 EKILQHSSL 1423
+K L +++L
Sbjct: 1316 QKNLLNANL 1324
Score = 105 bits (262), Expect = 3e-22
Identities = 172/726 (23%), Positives = 302/726 (41%), Gaps = 116/726 (15%)
Query: 763 TRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKR 822
TR G + E PE LK TIE K+SV N A MKDVQTS AE DLE+ASE EQ+R
Sbjct: 477 TRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQER 536
Query: 823 LEEYENNQPQVKNQ--------------IH--------SRDDLDDIIQSSQTVSEDGDSL 860
E ENNQPQV+ + IH DD D +IQ ++ D
Sbjct: 537 -EGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQF 595
Query: 861 -------------CCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQ 907
K V ++ + K+ V+ K L L ++ D+
Sbjct: 596 PRKENKEYASSGPALQMKEV-KSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDS--- 651
Query: 908 LRVKIRKL-KNKASVLQKRLSEKEEIKSQLKH--------ETLELEKELCSLRFAIQQEK 958
+ ++ +++ +K +EK ++K+Q++ ++ E E C L + K
Sbjct: 652 ---SLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHS--SYK 706
Query: 959 KKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNN--------- 1009
+E+L + ++ + + + Q +A ++ LK EL T
Sbjct: 707 NFMLLIEQLGMECKDSVSLLKIQ---DAALSCERLLELKKNHCELLTVKIKKMEDKVNVL 763
Query: 1010 SNQVSETDE-KEDLLHENRLMQDEIARLR--LEKDTIKNQNLEKKYLKDFEIVKRKHEDL 1066
++SET E K L H+ + E+ LR L ++ K +N + Y K E ++RK E
Sbjct: 764 QRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQY 823
Query: 1067 QKALKRNEETLAETIACYSGQLAALTDENTTLRSKLE---KQRESGQRLETEMQSYRCRL 1123
+K ++ ++ L L E T++S L ++R QR + Q+ R
Sbjct: 824 RKEVEVKQQ--------LELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQ 875
Query: 1124 NAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETEL 1183
+ L +H S +++ E+A + + H E LS + S + + +L E+
Sbjct: 876 DGILTNH---LSKQKEIEMAQKKMNSENSHSHEEEKD----LSHKNSMLQEEIAMLRLEI 928
Query: 1184 HYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE-RFCQLKKQN 1242
+EK + +LK + + +D++K K T+ + I + R L +N
Sbjct: 929 DTIKNQNQEKE---KKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAEN 985
Query: 1243 MLLQQQLDDARNKADNQEKAILNIQARCDARVENL-QAECRKHRLLLEEDNKMLVNELNH 1301
+L +L++ + + E + + +R A + + Q+E K L EL
Sbjct: 986 AMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKREL-----------ELAF 1034
Query: 1302 SKEK-KCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRK 1360
+ + +C ++K +V+ L+ + + + T++ L++ LE +R
Sbjct: 1035 QRARDECSRLQDKMNFDVS--NLKDNNEILSQQLFKTESKLNS-------LEIEFHHTRD 1085
Query: 1361 KLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQH 1420
L + + +Q L+ T KEME QK + E V + K I KQ+ ER ++
Sbjct: 1086 ALREKTLGLERVQKDLSQTQCQMKEME---QKYQNEQVKVNKYIGKQESVEERLSQLQSE 1142
Query: 1421 SSLMLQ 1426
+ L+ Q
Sbjct: 1143 NMLLRQ 1148
Score = 103 bits (257), Expect = 1e-21
Identities = 258/1354 (19%), Positives = 512/1354 (37%), Gaps = 213/1354 (15%)
Query: 137 ESENISEPYFTNRRTISQQSAEKLDAACGIDKTENGTLFEDQNVDKEG----KALPATGQ 192
+++N+ +P T SQQS + L+A G +T N TLFED++ D + ++LP T
Sbjct: 269 DTKNVPKPSLAKLMTASQQSRKNLEATYGTVRTGNRTLFEDRDSDSQDEVVVESLPTTSI 328
Query: 193 KANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAA 252
K F+H S + + S +S P L +KE +P+
Sbjct: 329 KVQ-------CFSHPTYQSPDLLPK---------PSHKSLANPGL----MKE-EPTKPGI 367
Query: 253 MRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDE 312
++++ G + P E+ +D+ V +
Sbjct: 368 AKKEN----GIDIIESAPLEQTNNDNLTYVDEV--------------------------H 397
Query: 313 KDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKK-VSLLNIATRITGGGKSGTVSSQKQ 371
K++ S++ + + GQ+ SP + F +K V L A GK + +++
Sbjct: 398 KNNRSDMMSALGLGQEEDIESPWDSESISENFPQKYVDPLAGA----ADGKEKNIGNEQA 453
Query: 372 P-----PSKATSDKTDSALNIATEIKDGLQCGTVSS-QKQPALKATTDEEDSVSNIATEI 425
PS + + + G+ + S ++ LK T + +DSV N A +
Sbjct: 454 EDVFYIPSCMSGSRNFKMAKLEDTRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGM 513
Query: 426 KDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDS 485
KD + S + L+ ++EE ++ E SE Q + K + E
Sbjct: 514 KDVQ----TSKAAEHDLEVASEEE----------QEREGSENNQPQVEEERKKHRNNEME 559
Query: 486 VSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALK 545
VS I DG +++ D + +++K GE +K
Sbjct: 560 VS---ANIHDGATD-------------DAEDDDDDDGLIQKRKSGETDHQQFPRKENKEY 603
Query: 546 ATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVS 605
A+S + + EK EK + S P LL + E +
Sbjct: 604 ASSGPALQMKEVKSTEK--EKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSE----ID 657
Query: 606 SHKQPALKATSDKENSVPNMATETKD----EQISGTVSSQKQPALKATSDKKDSVSNIPT 661
+ K TS+++N V N D Q S T S + + + + +
Sbjct: 658 EDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGM 717
Query: 662 EIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEK 721
E KD + + +KK+ + +IK + + V Q L T + K
Sbjct: 718 ECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNV---LQRELSETKEIK 774
Query: 722 DSVSN----IAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPE 777
+ + RE+ S +K+ +++K L R ++ E +
Sbjct: 775 SQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLR---RKEEQYRKEVEVKQ 831
Query: 778 ----NLPTLKATIENKNSVLNTATKMK-DVQTSTPAEQDLEMASEG----EQKRLEEYEN 828
+L TL+ + S LN + + D Q EQ+ M +G + +E E
Sbjct: 832 QLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEM 891
Query: 829 NQPQVKNQ-IHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLK- 886
Q ++ ++ HS ++ D+ + + E+ L + + E KC + + ++K
Sbjct: 892 AQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKE 951
Query: 887 ----IKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLE 942
++KT K+ E Q ++ L + ++L +L +++ K +L+ E
Sbjct: 952 KNEDLQKTI---KQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 1008
Query: 943 LEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVE 1002
L + Q + +R +E Q+ R++ +++ + K L ++
Sbjct: 1009 YHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEIL--SQQL 1066
Query: 1003 LKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRK 1062
KT ++ E D L E L + + + L + + + +E+KY + ++ K
Sbjct: 1067 FKTESKLNSLEIEFHHTRDALREKTLGLERVQK-DLSQTQCQMKEMEQKYQNE-QVKVNK 1124
Query: 1063 HEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCR 1122
+ Q++++ +L+ L EN LR +L+ E + + + +
Sbjct: 1125 YIGKQESVEE--------------RLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQ 1170
Query: 1123 LNAALCDHDQSHSSKRDQELAFQG--TVDKCCHLQ--------ENLNSHVLILSLQLSKA 1172
+ A+ Q+ S K+ L + + +C HL+ E V++ LQ A
Sbjct: 1171 FH-AIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELA 1229
Query: 1173 ES--KFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIE 1230
++ K + E L E + E +LK+K Q+++ + + + +C E
Sbjct: 1230 DTLKKQSMSEASL----EVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAE 1285
Query: 1231 K-QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVE-------------N 1276
K Q+ +L+K N L+ + +K + +K +LN D + + N
Sbjct: 1286 KMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECN 1345
Query: 1277 LQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEK-----------EKAEREVAVRQLQQ 1325
L E +K+ + LE + N L +++K +YE + E ++ + +L+
Sbjct: 1346 LDQEMKKN-VELEREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKH 1404
Query: 1326 KQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKE 1385
K DD+ A L+ + C++L+ Q +++L M+ T +C K
Sbjct: 1405 KIDDL-------TAELETAGSKCLHLDTKNQILQEELLSMK----------TVQKKCEK- 1446
Query: 1386 MEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQ 1419
++ + +KLE E + +R I++ ++ + ++ Q
Sbjct: 1447 LQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQ 1480
Score = 69.3 bits (168), Expect = 2e-11
Identities = 249/1258 (19%), Positives = 465/1258 (36%), Gaps = 224/1258 (17%)
Query: 293 PISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTV-------------------- 332
P++ S ++ K T + KDSV N A +K+ Q S
Sbjct: 483 PVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSENN 542
Query: 333 SPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPP--SKATSDKTDSALNIATE 390
PQ + K K + + + ++ I G K S +TD E
Sbjct: 543 QPQVEEERK---KHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKE 599
Query: 391 IKDGLQCGTVSSQKQPALKATTDE----EDSVSNIA-----------TEIKDGEKSGTVS 435
K+ G K+ +K+T E ++SV++ ++ D +
Sbjct: 600 NKEYASSGPALQMKE--VKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEID 657
Query: 436 SQKQPALKATTDEEDSVLNIATEIKD----GEKSETVSSQKQPALKATTDEEDSVSIIAT 491
+ K T++E++ V N + D + SET S + + + + +
Sbjct: 658 EDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGM 717
Query: 492 EIKDGE-----KSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKA 546
E KD + +S + LK E + E K + R +S K +
Sbjct: 718 ECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSETK----EI 773
Query: 547 TSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSS 606
S E + RE S E+ R D+L +K E+ RR
Sbjct: 774 KSQLEHQKVEWERELCSLRFSLNQEEEK-------RRNADTLY-----EKIREQLRRKEE 821
Query: 607 HKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTE--IK 664
+ ++ E S+ + E + TV S ++ +D + +S ++
Sbjct: 822 QYRKEVEVKQQLELSLQTLEMELR------TVKSNLNQVVQERNDAQRQLSREQNARMLQ 875
Query: 665 DGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSV 724
DG + +S QK++ + ++ S+ E KD + ++ + L+ D +
Sbjct: 876 DGILTNHLSKQKEIEMAQKKMNSEN-SHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKN- 933
Query: 725 SNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGT----------- 773
N +E K E V + + QK I + + +L ++ G T
Sbjct: 934 QNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLE 993
Query: 774 EYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMA---SEGEQKRLEEYEN-- 828
++ L+A +E+ +S L A + D S ++++LE+A + E RL++ N
Sbjct: 994 NEKQSKERLEAEVESYHSRL--AAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFD 1051
Query: 829 ------NQPQVKNQI---------------HSRDDLDDIIQSSQTVSEDGDSLCCNCKNV 867
N + Q+ H+RD L + + V +D C K +
Sbjct: 1052 VSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEM 1111
Query: 868 ILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKA-------- 919
++K I K + +RL++L+ + LR ++ NKA
Sbjct: 1112 EQKYQNEQVKVNK-----YIGKQESVEERLSQLQSENM-LLRQQLDDAHNKADNKEKTVI 1165
Query: 920 -------SVLQKRLSEKEEIKSQLKHETLELEKELCSLR---FAIQQEKKKRR-NVEELH 968
+++QK +E E+ L+ EL E L+ + + EK +R V +L
Sbjct: 1166 NIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQ 1225
Query: 969 QKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTG-GNNSNQVSET-DEKEDLLHEN 1026
Q++ + L+ + +VT + L+ +LK G NQ+ E D + +
Sbjct: 1226 QELADTLK-KQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCA 1284
Query: 1027 RLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSG 1086
MQD + +LEKD K + KK + K E+LQK L + E
Sbjct: 1285 EKMQDH--KQKLEKDNAKLKVTVKKQMD-------KIEELQKNLLNANLSEDE-----KE 1330
Query: 1087 QLAALTDENTTLRSKLEKQRESGQRLETEMQSY-------RCRLNAALCDHDQSHSSKRD 1139
QL L + +L L+++ + LE E+ + R +LN H +
Sbjct: 1331 QLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDLKT 1390
Query: 1140 QELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEH 1199
+ ++K H ++L + +L A SK L+T+ + L+E+ L +
Sbjct: 1391 SQFEMDIQINKLKHKIDDLTA-------ELETAGSKCLHLDTK----NQILQEELLSMKT 1439
Query: 1200 VQSELKQKQSQMKDIEKMYKSGYNTMEKCI----------------EKQERFCQLKKQNM 1243
VQ + ++ Q K +E+ + + +E+ + +QE +LK+ N+
Sbjct: 1440 VQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNL 1499
Query: 1244 LLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNK--------ML 1295
LQ Q N +E +++++ + R+++L++E K + E+ NK +
Sbjct: 1500 FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKYKQLY 1559
Query: 1296 VNELNHSKEKKCQYEKEKAE-REVAVRQLQQKQDD-VLNKRSATKALLDASSRHCIYLEN 1353
+ EL K + K EV + L +KQ L T+ +++ C+ N
Sbjct: 1560 LEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQSRSLFTTLTTRPVMEPP---CVGNLN 1616
Query: 1354 GMQDSRKKL-----------------DQMRSQFQEIQDQLTATIRCTKEMEGDAQKLE 1394
D +KL + M + ++Q +L I T+E++ A +LE
Sbjct: 1617 NSLDLNRKLIPRENLVISTSNPRASNNSMENYLSKMQQELEKNI--TRELKEAAAELE 1672
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 548 bits (1411), Expect = e-155
Identities = 329/692 (47%), Positives = 440/692 (63%), Gaps = 37/692 (5%)
Query: 689 SVSNIATEIKDGQIRGTVS----SQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 744
+ + A K IRG +S ++R+ +L+ + E+D E + E + PQ
Sbjct: 239 TAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298
Query: 745 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 804
+ K KK + ++ + Y +++ L I+N+ K
Sbjct: 299 EEKMKKCRNKK---MEVSRNVHAD--DSDNYNDDVDELIHKIKNR----------KPDNH 343
Query: 805 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 863
+P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + +
Sbjct: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397
Query: 864 CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ 923
+N +LLI Q M+CKD V L K K C R E + +CE+L+VK +K+KN SVLQ
Sbjct: 398 DENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457
Query: 924 KRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 983
K LSE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR
Sbjct: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517
Query: 984 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 1042
+ +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT
Sbjct: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577
Query: 1043 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRS 1100
IK+QN E KY KD EI+K +EDL+K LKRNEETL +TI YS +L L DENT L S
Sbjct: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637
Query: 1101 KLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNS 1160
+L+K+++S RLETEM+SYRCRL AALCDHDQ SSKRD +LAFQ TV++ CHLQE+ NS
Sbjct: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697
Query: 1161 HVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 1220
H+ ILS QLSKAES LETELHY EALKEK L EH+Q L + Q +++DIE MY++
Sbjct: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757
Query: 1221 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVEN 1276
+EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ VE
Sbjct: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817
Query: 1277 LQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSA 1336
LQAECRK LEE+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK+
Sbjct: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873
Query: 1337 TKALLDASSRHCIYLENGMQDSRKKLDQMRSQ 1368
+A+L+ SS I LE+ Q +KKL QMRSQ
Sbjct: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 548 bits (1411), Expect = e-155
Identities = 329/692 (47%), Positives = 440/692 (63%), Gaps = 37/692 (5%)
Query: 689 SVSNIATEIKDGQIRGTVS----SQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 744
+ + A K IRG +S ++R+ +L+ + E+D E + E + PQ
Sbjct: 239 TAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298
Query: 745 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 804
+ K KK + ++ + Y +++ L I+N+ K
Sbjct: 299 EEKMKKCRNKK---MEVSRNVHAD--DSDNYNDDVDELIHKIKNR----------KPDNH 343
Query: 805 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 863
+P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + +
Sbjct: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397
Query: 864 CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ 923
+N +LLI Q M+CKD V L K K C R E + +CE+L+VK +K+KN SVLQ
Sbjct: 398 DENFMLLIKQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457
Query: 924 KRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 983
K LSE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR
Sbjct: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517
Query: 984 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 1042
+ +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT
Sbjct: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577
Query: 1043 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRS 1100
IK+QN E KY KD EI+K +EDL+K LKRNEETL +TI YS +L L DENT L S
Sbjct: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNS 637
Query: 1101 KLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNS 1160
+L+K+++S RLETEM+SYRCRL AALCDHDQ SSKRD +LAFQ TV++ CHLQE+ NS
Sbjct: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697
Query: 1161 HVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 1220
H+ ILS QLSKAES LETELHY EALKEK L EH+Q L + Q +++DIE MY++
Sbjct: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757
Query: 1221 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVEN 1276
+EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ VE
Sbjct: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817
Query: 1277 LQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSA 1336
LQAECRK LEE+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK+
Sbjct: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873
Query: 1337 TKALLDASSRHCIYLENGMQDSRKKLDQMRSQ 1368
+A+L+ SS I LE+ Q +KKL QMRSQ
Sbjct: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 545 bits (1405), Expect = e-155
Identities = 328/692 (47%), Positives = 439/692 (63%), Gaps = 37/692 (5%)
Query: 689 SVSNIATEIKDGQIRGTVS----SQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQK 744
+ + A K IRG +S ++R +L+ + E+D E + E + PQ
Sbjct: 239 TAEDYAVASKFQAIRGMISEYKANKRCKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQV 298
Query: 745 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQT 804
+ K KK + ++ + Y +++ L I+N+ K
Sbjct: 299 EEKMKKCRNKK---MEVSRNVHAD--DSDNYNDDVDELIHKIKNR----------KPDNH 343
Query: 805 STPAEQDLEMASEGEQKRL-EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 863
+P +++ GE RL + N + +VK+QI+ DDL+DI SS+ SED + +
Sbjct: 344 QSPGKEN------GEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYSD 397
Query: 864 CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQ 923
+N +LLI+Q M+CKD V L K K C R E + +CE+L+VK +K+KN SVLQ
Sbjct: 398 DENFMLLIEQSGMECKDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQ 457
Query: 924 KRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 983
K LSE ++ KSQ +H+ L+ +K+LC+LRF +QQ++++R EEL++K E+L+I EEQYR
Sbjct: 458 KVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYR 517
Query: 984 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDT 1042
+ +V K K LKS EVELKT +NSNQ T E+E DL EN LM+DEIARLRLE DT
Sbjct: 518 TQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDT 577
Query: 1043 IKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRS 1100
IK+QN E KY KD EI+K +EDL+K LKRNEE L +TI YS +L L DENT L S
Sbjct: 578 IKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNS 637
Query: 1101 KLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNS 1160
+L+K+++S RLETEM+SYRCRL AALCDHDQ SSKRD +LAFQ TV++ CHLQE+ NS
Sbjct: 638 ELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWCHLQEDTNS 697
Query: 1161 HVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKS 1220
H+ ILS QLSKAES LETELHY EALKEK L EH+Q L + Q +++DIE MY++
Sbjct: 698 HIQILSQQLSKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQN 757
Query: 1221 GYNTMEKCIEKQER----FCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVEN 1276
+EK + KQ+ QL+ QN+L QQQ +DAR KADNQEK I+NIQ +C+ VE
Sbjct: 758 DQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEK 817
Query: 1277 LQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSA 1336
LQAECRK LEE+NK L+ E KE++CQYEKEK EREV RQLQ++ DD LNK+
Sbjct: 818 LQAECRK----LEENNKGLMKECTLLKERQCQYEKEKEEREVVRRQLQREVDDALNKQLL 873
Query: 1337 TKALLDASSRHCIYLENGMQDSRKKLDQMRSQ 1368
+A+L+ SS I LE+ Q +KKL QMRSQ
Sbjct: 874 LEAMLEISSERRINLEDEAQSLKKKLGQMRSQ 905
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 383 bits (983), Expect = e-106
Identities = 359/1226 (29%), Positives = 568/1226 (46%), Gaps = 134/1226 (10%)
Query: 156 SAEKLDAACGIDKTENGTLFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDSDHIS 215
+AE CG + + + K + G A E PL T ++ +
Sbjct: 184 TAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLV 243
Query: 216 TRFLGSMDSLT-----SSEESSERPPLSTLTLKEADPSSKAAMRRKDS---------PPP 261
+ L ++E E+ P +L E + + S P
Sbjct: 244 EKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPR 303
Query: 262 GKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIAT 321
S K+ +EK T K IA E KE +S K+ +EK T K IA
Sbjct: 304 EITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAW 363
Query: 322 EIKEGQ-QSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSG------TVSSQKQPPS 374
E KE ++G V+ + KV+ K + ++ T+ + S + S Q++
Sbjct: 364 EKKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEE 423
Query: 375 KATSDKT--DSALNIATEIKDGLQCGTVS--------SQKQPALKATTDEEDSVSNIATE 424
+ ++ +S+ I I + + + +K A K + ++SV N A E
Sbjct: 424 YSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQNSVPNKAFE 483
Query: 425 IKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEED 484
+K+ E++ P K EE+S D E SQK L T +++
Sbjct: 484 LKN-EQTLRADPMFPPESKQKDYEENSW--------DSESLCETVSQKDVCLPKATHQKE 534
Query: 485 SVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPAL 544
+ I ++++ S K LKAT K S E KD + + KP A
Sbjct: 535 -IDKINGKLEE-------SPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAF 586
Query: 545 KATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRV 604
+ ++ + SV + A E K+ + R + L + ++ K Y E +
Sbjct: 587 EPATEMQKSVPNKALELKNEQTLRA---------------DEILPSESKQKDYEENSWDT 631
Query: 605 SSHKQPALKATSDKENSVPNMATETKDEQISGTV--SSQKQPALKATSDKKDSVSNIPTE 662
S + S K+ +P A + + ++I+G + S K LKA K S+ E
Sbjct: 632 ES----LCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALE 687
Query: 663 IKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQ------IRGTVSSQRQ----- 711
+ D Q +K A++ + SV N A E+K+ Q I + S Q+
Sbjct: 688 LMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESS 747
Query: 712 ---PALKATGDEKDSVSNIAREIKDGEK-SGTV--SPQKQSAQKVIFKKKVSLLNIATRI 765
+L T +KD A K+ +K +G + SP K + KVS+ A +
Sbjct: 748 WDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALEL 807
Query: 766 TGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEE 825
E PE + IE + SV N A ++K+ QT D SE +QK++EE
Sbjct: 808 MDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQT---LRADQMFPSESKQKKVEE 864
Query: 826 YENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLL 885
+ ++ + +D +C +D+ K +D L
Sbjct: 865 NSWDSESLRETVSQKD------------------VCVPKATHQKEMDKISGKLEDSTSLS 906
Query: 886 KIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEK 945
KI T C+R EL+ +HCEQ K+ ++K K VL+K+LSE +EIKSQL+++ ++ E+
Sbjct: 907 KILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQ 966
Query: 946 ELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKT 1005
ELCS+R + QE++KRRN + L++K+RE+L EEQ+R E +V + ++ AL+ ++ELK+
Sbjct: 967 ELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKS 1026
Query: 1006 GGNNSNQVSETDEKED-LLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRK 1062
+N NQVS T E E+ LLHEN +++ EIA L+LE T+K+Q EK KY +D +I+K K
Sbjct: 1027 VESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEK 1086
Query: 1063 HEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCR 1122
+ +LQ LK EE+L + + YSGQL L ENT L SKL K+++ + LE E++S+ R
Sbjct: 1087 NAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAEIESHHPR 1145
Query: 1123 LNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVL-------ILSLQLSKAESK 1175
L +A+ DHDQ +S++ QE AF D C LQ +N V +L LS+A+ K
Sbjct: 1146 LASAVQDHDQIVTSRKSQEPAFHIAGDAC--LQRKMNVDVSSTIYNNEVLHQPLSEAQRK 1203
Query: 1176 FRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE-- 1233
+ L+ L+Y G+AL+E LV EH Q + ++ Q QMK+ E MY++ + + K E+QE
Sbjct: 1204 SKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESL 1263
Query: 1234 --RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEED 1291
+ QL+ +NM LQQQL A KADN+ K ++I L+ + + H LL+E
Sbjct: 1264 DQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF--------LERKMQHH--LLKEK 1313
Query: 1292 NKMLVNELNHSKEKKCQYEKEKAERE 1317
N+ + N NH K + QYEKEKAE E
Sbjct: 1314 NEEIFNYNNHLKNRIYQYEKEKAETE 1339
Score = 76.3 bits (186), Expect = 2e-13
Identities = 218/1134 (19%), Positives = 427/1134 (37%), Gaps = 158/1134 (13%)
Query: 370 KQPPSKATS--DKT-DSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIK 426
++ P A S +KT D A ++ D +QC +K + K E++ I + K
Sbjct: 255 ERTPDTAESLVEKTPDEAASLVEGTSDKIQC----LEKATSGKFEQSAEETPREITSPAK 310
Query: 427 DGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSV 486
+ + T ++ +P A +ED+ I + K+ + T +++ +P A +E V
Sbjct: 311 ETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKETPV 370
Query: 487 SIIA--------TEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSS 538
T++ + +S ++ K + S F + +++++D E S S
Sbjct: 371 KTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRS 430
Query: 539 QKPPALKATSDEEDS----VLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARG 594
+ K +S V+ I RE ++ K +P K + ++S+ N A
Sbjct: 431 LFESSAKIQVCIPESIYQKVMEINREVEEPPK-------KPSAFKPAIEMQNSVPNKAFE 483
Query: 595 KKYGEKTRRVSSHKQPALKATSDKENS----------------VPNMATETKDEQISGTV 638
K E+T R P K +ENS +P + + ++I+G +
Sbjct: 484 LK-NEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKL 542
Query: 639 --SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATE 696
S K LKAT K S+ E+KD Q K A++ + + SV N A E
Sbjct: 543 EESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALE 602
Query: 697 IKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEK-SGTVSPQKQSAQKVIFKKK 755
+K+ Q + + L + +KD N D E TVS + K +K+
Sbjct: 603 LKNEQ-----TLRADEILPSESKQKDYEENSW----DTESLCETVSQKDVCLPKAAHQKE 653
Query: 756 VSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMA 815
+ +N G G+ + L LKA K S+ A ++ D+QT + A
Sbjct: 654 IDKIN-------GKLEGSPVKDGL--LKANCGMKVSIPTKALELMDMQTFKAEPPEKPSA 704
Query: 816 SEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHE 875
E + + N ++KN+ R D I S++ +D + + +++ + Q +
Sbjct: 705 FEPAIEMQKSVPNKALELKNEQTLRADE---ILPSESKQKDYEESSWDSESLCETVSQKD 761
Query: 876 MKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLS--EKEEIK 933
+ H +I K + +L E DN L+ R K S+ K L + + K
Sbjct: 762 VCLPKATHQKEIDK---INGKLEESPDND-GFLKAPCRM---KVSIPTKALELMDMQTFK 814
Query: 934 SQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIK 993
++ + E + E+ + V K + + + AD P +
Sbjct: 815 AEPPEKPSAFEPAI------------------EMQKSVPNKALELKNEQTLRADQMFPSE 856
Query: 994 PALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARL--RLEKDTIKNQNLEKK 1051
K E +S + ET ++D+ Q E+ ++ +LE T ++ L
Sbjct: 857 SKQKKVE----ENSWDSESLRETVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKIL--- 909
Query: 1052 YLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQR 1111
D + +R E + +G++ + + L+ KL + +E +
Sbjct: 910 -------------DTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQ 956
Query: 1112 LETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQ------GTVD----KCCHLQENLNSH 1161
LE + + L + +Q +R+ ++ + G ++ K +++ L
Sbjct: 957 LENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQA 1016
Query: 1162 VLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHV---QSELKQKQSQMKDIEKMY 1218
+ I ++L ES + L E ++ + + + E+ + Q ++ E Y
Sbjct: 1017 LRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKY 1076
Query: 1219 KSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQ 1278
+++ + + +LK++++ + + K E +L + + E L+
Sbjct: 1077 FEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKLKEKQDKEILE 1136
Query: 1279 AECRKHRLLLE---EDNKMLVNELN------HSKEKKCQYEKEKAEREVAVRQ---LQQK 1326
AE H L +D+ +V H C K + + L Q
Sbjct: 1137 AEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDACLQRKMNVDVSSTIYNNEVLHQP 1196
Query: 1327 QDDVLNKRSATKALL----DASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRC 1382
+ K + K L DA + + E+ +D R+ QM+ Q++ +
Sbjct: 1197 LSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKH 1256
Query: 1383 TKEMEGDAQK---LEVENVMMRKII----KKQDEQ------IERFEKILQHSSL 1423
T++ E QK L+ +N+ +++ + KK D + I E+ +QH L
Sbjct: 1257 TEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHFLERKMQHHLL 1310
Score = 54.3 bits (129), Expect = 8e-07
Identities = 177/930 (19%), Positives = 350/930 (37%), Gaps = 118/930 (12%)
Query: 531 EISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLN 590
++S+ + P A + +E + L+ + E P ++ T D +SL+
Sbjct: 207 KLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPDEAAPLVERTPDTAESLVE 266
Query: 591 IARGKKYGEKTRRVSSHKQPALKATSDK-----ENSVPNMATETKDEQISGTVSSQKQPA 645
+ S Q KATS K E + + + K+ T ++ +P
Sbjct: 267 KTPDEA-ASLVEGTSDKIQCLEKATSGKFEQSAEETPREITSPAKETSEKFTWPAKGRPR 325
Query: 646 LKATSDKKDSVSNIPTEIKDGQQSGTVSSQ---KQLAW--KATSVKKDSVSNIATE---- 696
A K+D+ I + K+ + T +++ +++AW K T VK V+ + +
Sbjct: 326 KIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKETPVKTGCVARVTSNKTKV 385
Query: 697 IKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKV 756
++ G+ + ++ + KA+ +++ S +E +D E S +S+ K+
Sbjct: 386 LEKGRSKMIACPTKESSTKASANDQRFPSESKQE-EDEEYSCDSRSLFESSAKIQVCIPE 444
Query: 757 SLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMAS 816
S+ I + E P+ K IE +NSV N A ++K+ QT D
Sbjct: 445 SIYQKVMEIN---REVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQT---LRADPMFPP 498
Query: 817 EGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEM 876
E +QK +YE N ++ + D + + E ID+
Sbjct: 499 ESKQK---DYEENSWDSESLCETVSQKDVCLPKATHQKE---------------IDKING 540
Query: 877 KCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQL 936
K ++ + + K C K K + ++ + K S + E++ +
Sbjct: 541 KLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPAT----EMQKSV 596
Query: 937 KHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPAL 996
++ LEL+ E I + K+++ EE + E L T Q DV P A
Sbjct: 597 PNKALELKNEQTLRADEILPSESKQKDYEE-NSWDTESLCETVSQ----KDVCLP--KAA 649
Query: 997 KSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLE---KDTIKNQNLEKKYL 1053
E++ G + V K+ LL N M+ I LE T K + EK
Sbjct: 650 HQKEIDKINGKLEGSPV-----KDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSA 704
Query: 1054 KDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESG---- 1109
+ I +K + +NE+TL DE SK + ES
Sbjct: 705 FEPAIEMQKSVPNKALELKNEQTLR-------------ADEILPSESKQKDYEESSWDSE 751
Query: 1110 QRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVL-ILSLQ 1168
ET Q C A + K ++ G + C ++ ++ + L ++ +Q
Sbjct: 752 SLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQ 811
Query: 1169 LSKAE--SKFRVLETELHYTGEALKEKALVFEHVQS----ELKQKQSQMKDIEKMYKSGY 1222
KAE K E + +++ KAL ++ Q+ ++ +S+ K +E+
Sbjct: 812 TFKAEPPEKPSAFEPAIEMQ-KSVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSE 870
Query: 1223 NTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECR 1282
+ E +K C K + Q+++D K ++ +++ + C
Sbjct: 871 SLRETVSQKD--VCVPKATH---QKEMDKISGKLEDSTSL---------SKILDTVHSCE 916
Query: 1283 KHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLD 1342
+ R L ++ + ++ K+K C +K+ +E + QL+ ++ + + + L
Sbjct: 917 RARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTL- 975
Query: 1343 ASSRHCIYLENGMQDSRKKLD----QMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENV 1398
N ++ R+ D ++R + I++Q + +++E Q L ++++
Sbjct: 976 ----------NQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLE---QALRIQDI 1022
Query: 1399 MMRKIIK--KQDEQIERFEKILQHSSLMLQ 1426
++ + Q E L H + ML+
Sbjct: 1023 ELKSVESNLNQVSHTHENENYLLHENCMLK 1052
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 382 bits (981), Expect = e-105
Identities = 253/667 (37%), Positives = 374/667 (56%), Gaps = 63/667 (9%)
Query: 810 QDLEMASEGEQKR-LEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVI 868
Q + GE R ++ N + +VKNQI+ D D ++ S+ SED + +N +
Sbjct: 560 QQIPRKENGEHDRPADKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFM 619
Query: 869 LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSE 928
LLI+Q M+ KD L +I+ TFCLC+ L +LK+NHC+QL VK+++++N SVLQ LSE
Sbjct: 620 LLIEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSE 679
Query: 929 KEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADV 988
++ K QL+ + +E EKEL LR A++QE +++RN + L+ K E+LRI EE+ +
Sbjct: 680 TKKTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVET 739
Query: 989 TKPIKPALKSAEVELKTGGNN--------------------------------------- 1009
+ +K L+ EL+T NN
Sbjct: 740 KQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMA 799
Query: 1010 ----SNQVSETDEKE-DLLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDFEIVKRK 1062
++++S +KE DL HE+ ++Q+EIA LRLE DTIKNQN EKKY +D E VK K
Sbjct: 800 RKKMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEK 859
Query: 1063 HEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCR 1122
+++LQK +K NEETL ETI YSGQL LT EN L S+LE +++ +RLE EM+SYRCR
Sbjct: 860 NDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCR 919
Query: 1123 LNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQE-------NLNSHVLILSLQLSKAESK 1175
L AA+ D DQS ++ RD +L FQ T + L + L + ILS +LS AESK
Sbjct: 920 LAAAVRDCDQSQTA-RDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESK 978
Query: 1176 FRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ--- 1232
L+ +LH T +AL ++L+ E VQ +L Q Q Q K+ E+MY+ + ++K I KQ
Sbjct: 979 INSLQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESV 1038
Query: 1233 -ERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEED 1291
ER QL+ +NMLL+QQLDDA KA++QEK IQ + + +NLQAE K L L+E
Sbjct: 1039 EERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEK 1098
Query: 1292 NKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDASSRHCIYL 1351
NK L++E NH KE+ Q EKEKA R++ + + Q+ A +L + ++
Sbjct: 1099 NKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQL--QQTLFS 1156
Query: 1352 ENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQ--KLEVENVMMRKIIKKQDE 1409
+Q + L + + Q ++ L + + G A+ KL +E ++I +K +E
Sbjct: 1157 MKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEEKLNE 1216
Query: 1410 QIERFEK 1416
I +K
Sbjct: 1217 AILTLQK 1223
Score = 76.3 bits (186), Expect = 2e-13
Identities = 165/839 (19%), Positives = 325/839 (38%), Gaps = 149/839 (17%)
Query: 686 KKDSVSNIATEIKDGQIRGTVSSQRQPALKATG-DEKDSVSNIAREIKDGEKSGTVSPQK 744
+K S+ + E K+ Q ++ P T D ++ +K +K +VSP
Sbjct: 112 RKKSIQQLVPEYKEKQTPESLPQNNNPDWHPTNLTLSDETCQRSKNLKVDDKCPSVSPSM 171
Query: 745 QSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTA-TKMKDVQ 803
Q K++ +N+ R E + T + +++ + +++ + +
Sbjct: 172 PENQSAT--KELGQMNLTER------------EKMDTGVVLLSGNDTLHDLCQSQLPENK 217
Query: 804 TSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQ---IHSRDDLDDI--------IQSSQT 852
S AEQD E+ SE EQ+RL+ EN QPQ +Q + D +DI +Q S+
Sbjct: 218 ESKEAEQDSELTSEEEQERLKGCENKQPQKTSQEPEMAKDCDREDIPIYPVLPHVQKSEE 277
Query: 853 VSEDGDSLCCNCKNVI-LLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVK 911
+ + L KN + L+I++ + + + KI C L DN VK
Sbjct: 278 MWIEQGKL--EWKNQLKLVINELKQRFGEIYEKYKIP----ACPEEEPLLDNSTRGTDVK 331
Query: 912 IRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKE--------------------LC--S 949
++ + EI + ET +KE +C S
Sbjct: 332 DIPFNLTNNIPGCEEEDASEISVSVVFETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSS 391
Query: 950 LRFAIQQEK---------------------------KKRRNVEELHQKVRE----KLRIT 978
+F + + K KK RN E + +++E L++T
Sbjct: 392 SKFHLHENKLDCDNDNKPGIGHIFSTDKNFHNDASTKKARNPEVVMVEMKEDQEFDLQMT 451
Query: 979 EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRL 1038
+ + + +LK L + +S++ SE E+L + + ++E+ L
Sbjct: 452 KNMNQNSDSGSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQDMQKFKNEVNTLEE 511
Query: 1039 EKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALK---------------RNEETLAETIAC 1083
E +K ++++ KD E KH L N++ +
Sbjct: 512 EFLALKKEDVQLH--KDVEEEMEKHRSNSTELSGTLTDGTTVGNDDDGLNQQIPRKENGE 569
Query: 1084 YSGQLAALTDENTTLRSKLEKQRESGQRLE-TEMQSYRCRLNAALCDH-----DQSHSSK 1137
+ ++E +++++ + + +E +E+ S C L+ ++ ++ +Q
Sbjct: 570 HDRPADKTSNEKNEVKNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEY 629
Query: 1138 RDQEL--AFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEA---LKE 1192
+D Q T C HL + N+H L+++L + E+ VL+ EL T + L+
Sbjct: 630 KDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLEL 689
Query: 1193 KALVFE----HVQSELKQKQSQMKDIEKMYKSGYNTM----EKCIEKQERFCQLKKQNML 1244
+ + +E ++ LKQ+ + ++ + +Y + E+C + E QLK
Sbjct: 690 QKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRR 749
Query: 1245 LQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKE 1304
L ++L RN D L +Q R DA + +L E+D ++L +++ SK+
Sbjct: 750 LVKELRTVRNNLD------LVVQERNDA----------QKQLSEEQDARILQDQILTSKQ 793
Query: 1305 KKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQ 1364
K+ + ++K E++ R QK+ D+ ++ + + ++N + KK +
Sbjct: 794 KELEMARKKMNSEISHR--HQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFE 851
Query: 1365 MRSQFQEIQDQLTATIRCTKE--------MEGDAQKLEVENVMMRKIIKKQDEQIERFE 1415
+E D L I+ +E G L EN ++ ++ + ER E
Sbjct: 852 DIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLE 910
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 328 bits (840), Expect = 3e-89
Identities = 346/1214 (28%), Positives = 552/1214 (45%), Gaps = 122/1214 (10%)
Query: 156 SAEKLDAACGIDKTENGTLFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDSDHIS 215
+AE+ AACG++ L + + K + G E PL T ++ +
Sbjct: 240 TAERYAAACGVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLL 299
Query: 216 TRFLGSMDSLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKAT 275
+ L S++ L T + + S++ R+ P K+ +EK +
Sbjct: 300 EKTPDEAARLVEGT-SAKIQCLGKATSGKFEQSTEETPRKILRPT-------KETSEKFS 351
Query: 276 SDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQ 335
K+ I E KE +S K + K V +++G + P
Sbjct: 352 WPAKERSRKITWEEKE-------TSVKTECVAGVTPNKTEV------LEKGTSNMIACPT 398
Query: 336 KQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEI--KD 393
K+++ K VS + + G + T+ + + K + N+AT+I K
Sbjct: 399 KETSTKASTNVDVSSVEPIFSLFG---TRTIENSQ-------CTKVEEDFNLATKIISKS 448
Query: 394 GLQCGTV--SSQKQPALKATTD--EEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEE 449
Q T + Q +K E+ + + +D E S S + + K
Sbjct: 449 AAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREEDEEYSWDSGSLFESSAKTQVCIP 508
Query: 450 DSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPA 509
+S+ EI + +K A K + + +V A E+K+ + + R
Sbjct: 509 ESMYQKVMEIN---REVEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ-----TLRAAQM 560
Query: 510 LKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREE---KDGEK 566
+ S +KD N + E TVS + KAT +E LS EE KDG
Sbjct: 561 FPSESKQKDDEENSWDSESPCE---TVSQKDVYLPKATHQKEFDTLSGKLEESPVKDGL- 616
Query: 567 SRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMA 626
LK T K SL N A K E + S K LK T ++ S+PN A
Sbjct: 617 -----------LKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKA 665
Query: 627 TETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKD------GQQSGTVSSQK---Q 677
E KD + S LK T +K S+ N E+KD Q + S QK +
Sbjct: 666 LELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDEE 725
Query: 678 LAWKATSVKKDSVSNI-----ATEIKD-GQIRGTV--SSQRQPALKATGDEKDSVSNIAR 729
+W S + + N AT K+ + G + S + LK T K S+ N A
Sbjct: 726 NSWDFESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKAL 785
Query: 730 EIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENK 789
E+KD E + +F K + + +T++ + T+ T+ E
Sbjct: 786 ELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGAT-KTVTGQQERD 844
Query: 790 NSVLNTATKMKDVQTSTPA---EQDLEMASEGEQKRLEEYENNQ--PQVKNQIHSRDDLD 844
++ A + + + T ++D + S+ E + + +N + P+ Q +
Sbjct: 845 IGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNG 904
Query: 845 DIIQSSQTVS--EDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKD 902
I +S + S E + + N L + D L KI C+R ELK
Sbjct: 905 KIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKK 964
Query: 903 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRR 962
++CEQ+ K+ + KNK VLQK LSE +EIKSQL+++ + E+ELCS+R + QE++KRR
Sbjct: 965 DNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRR 1024
Query: 963 NVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE-D 1021
NV+ L +K+R EEQ R + +V + ++ L+ ++ELK+ +N NQVS T E E D
Sbjct: 1025 NVDILKEKIR-----PEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESEND 1079
Query: 1022 LLHENRLMQDEIARLRLEKDTIKNQN--LEKKYLKDFEIVKRKHEDLQKALKRNEETLAE 1079
L HEN +++ EIA L+LE T+K+Q+ E KY +D +I++ K+ +LQ LK ++T+ +
Sbjct: 1080 LFHENCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTK 1139
Query: 1080 TIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRD 1139
+ Y QL LT ENT L SKL K+++ + LETE++S+ RL +AL DHDQS +S+++
Sbjct: 1140 RASQYREQLKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKN 1198
Query: 1140 QELAFQGTVDKCCHLQENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGEALKE 1192
QELAF D LQ +N V +L L +A+ K + + L+Y G+ L+E
Sbjct: 1199 QELAFHSAGD--APLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRE 1256
Query: 1193 KALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE----RFCQLKKQNMLLQQQ 1248
ALV EH Q + + Q QMK E MY++ + ++K E+QE + QL+ +N L+QQ
Sbjct: 1257 NALVSEHAQRDRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQ 1316
Query: 1249 LDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQ 1308
L A K N+ K +NIQ + + ++H L E N+ + N NH KE+ Q
Sbjct: 1317 LVYAHKKV-NKSKVTINIQFP--------EMKMQRH---LNEKNEEVFNYGNHLKERIDQ 1364
Query: 1309 YEKEKAEREVAVRQ 1322
YEKEKAEREV++++
Sbjct: 1365 YEKEKAEREVSIKK 1378
Score = 33.9 bits (76), Expect = 1.2
Identities = 98/439 (22%), Positives = 168/439 (38%), Gaps = 54/439 (12%)
Query: 18 LEVSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVT 77
+E +K A K + +V N A E+K+EQ L A + + S + D +
Sbjct: 522 VEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ----TLRAAQMFPSESKQKDD--EENSW 575
Query: 78 EDEFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYLLDRFAQAVTKDKFALE 137
+ E E+ +Y+P K + + + +EE+ + L + V+ ALE
Sbjct: 576 DSESPCETVSQKDVYLP--KATHQKEFDTLSGKLEESPVKDGLLKPTCGRKVSLPNKALE 633
Query: 138 SENISEPYFTNRRTISQQSAEK---LDAACG---------IDKTENGTLFEDQNVDKEGK 185
+R T +S +K L CG ++ + TL + ++ D +G
Sbjct: 634 --------LKDRETFKAESPDKDGLLKPTCGRKVSLPNKALELKDRETL-KAESPDNDGL 684
Query: 186 ALPATGQKANVSPEQPPLFTHTVKDSDHISTRFLGSMDSLTSSEESSERPPLSTL-TLKE 244
P G+K ++ P +KD + + +S +E + S L TL +
Sbjct: 685 LKPTCGRKVSL-----PNKALELKDRETFKAAQMFPSESKQKDDEENSWDFESFLETLLQ 739
Query: 245 ADPS-SKAAMRRKDSPPPGKV--SSQKQPAEKATSDDKDSVSNIATEIKE---------G 292
D KA +++ GK+ S K K T K S+ N A E+K+
Sbjct: 740 NDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVS 799
Query: 293 PISGTVSSQKQP-AEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLL 351
+ T S +P E + S + + N+ T KEG + TV+ Q++ +I +
Sbjct: 800 SVESTFSLFGKPTTENSQSTKVEEDFNLTT--KEG-ATKTVTGQQERDIGIIERAPQDQT 856
Query: 352 NIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIAT---EIKDGLQCGTVSSQKQPAL 408
N G K T S+ + + L AT EIK S +K
Sbjct: 857 NKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIKTTNGKIEESPEKPSHF 916
Query: 409 KATTDEEDSVSNIATEIKD 427
+ T+ ++SV N E K+
Sbjct: 917 EPATEMQNSVPNKGLEWKN 935
Score = 32.7 bits (73), Expect = 2.6
Identities = 28/170 (16%), Positives = 75/170 (44%), Gaps = 17/170 (10%)
Query: 1259 QEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREV 1318
+ K L + +++ + C + R L +++ + + ++ +K K C +KE +E +
Sbjct: 934 KNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKE 993
Query: 1319 AVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1378
QL+ ++ + + + L N ++ R+ +D ++ + + ++QL
Sbjct: 994 IKSQLENQKAKWEQELCSVRLTL-----------NQEEEKRRNVDILKEKIRP-EEQLRK 1041
Query: 1379 TIRCTKEMEGDAQKLEVENVMMRKIIK--KQDEQIERFEKILQHSSLMLQ 1426
+ +++E Q L ++++ ++ + Q E L H + ML+
Sbjct: 1042 KLEVKQQLE---QTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLK 1088
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 252 bits (644), Expect = 2e-66
Identities = 190/574 (33%), Positives = 296/574 (51%), Gaps = 95/574 (16%)
Query: 764 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 823
RI G G P P+LK + E ++ + A + K+VQT AEQ L +ASE EQ+R
Sbjct: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
Query: 824 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 883
E E QPQ +I+ + T +
Sbjct: 376 ERSEKKQPQ-------------VIEGNNTYKSE--------------------------- 395
Query: 884 LLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---T 940
KI +L +N C + S RL+++ +I +
Sbjct: 396 --KI-----------QLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
Query: 941 LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 1000
L+ E + C+L+ QE +++ NV LH+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
Query: 1001 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 1057
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
Query: 1058 IVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQ 1117
I K + L+K +K NEE + +T Y +L L ENT L S+L K++ES ++LE E++
Sbjct: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
Query: 1118 SYRCRLNAALCDHDQSHSSKRDQELAFQGTVD-----KCCHLQENLNSHVLILSLQLSKA 1172
SY+ RL AA+ H ++ ++R+ +LA + T D K + L+ QLSK
Sbjct: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
Query: 1173 ESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 1231
+ KF L+ + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
Query: 1232 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 1288
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
Query: 1289 EEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQ 1322
EE NK L+NE +H KE QYE++KAE V++++
Sbjct: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 252 bits (644), Expect = 2e-66
Identities = 190/574 (33%), Positives = 296/574 (51%), Gaps = 95/574 (16%)
Query: 764 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 823
RI G G P P+LK + E ++ + A + K+VQT AEQ L +ASE EQ+R
Sbjct: 319 RIVNGKGEGP--PAKHPSLKPSTEMEDPAVKGAVQXKNVQTLR-AEQALPVASEEEQQRR 375
Query: 824 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 883
E E QPQ +I+ + T +
Sbjct: 376 ERSEKKQPQ-------------VIEGNNTYKSE--------------------------- 395
Query: 884 LLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---T 940
KI +L +N C + S RL+++ +I +
Sbjct: 396 --KI-----------QLSENICH----------STFSAAADRLTQQRKIGKTYPQQFPKK 432
Query: 941 LELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAE 1000
L+ E + C+L+ QE +++ NV LH+K RE+L E+QY+ E + K ++P ++S E
Sbjct: 433 LKEEHDRCTLK----QENEEKTNVNMLHKKNREELERKEKQYKKEVEA-KQLEPTVQSLE 487
Query: 1001 VELKTGGNNSNQ-VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFE 1057
++ KT N NQ +E +DL+ EN +++ +IA LR E T+KN NLEK KYLKD +
Sbjct: 488 MKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIK 547
Query: 1058 IVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQ 1117
I K + L+K +K NEE + +T Y +L L ENT L S+L K++ES ++LE E++
Sbjct: 548 IAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIE 607
Query: 1118 SYRCRLNAALCDHDQSHSSKRDQELAFQGTVD-----KCCHLQENLNSHVLILSLQLSKA 1172
SY+ RL AA+ H ++ ++R+ +LA + T D K + L+ QLSK
Sbjct: 608 SYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKM 667
Query: 1173 ESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK- 1231
+ KF L+ + T + L++K+L E VQ++L Q Q Q+K++++MY+S + K K
Sbjct: 668 QIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGKW 727
Query: 1232 ---QERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLL 1288
+ER CQL+++N L+QQL D K D++E ++NIQ E RK L+L
Sbjct: 728 NCVEERICQLQRENPWLEQQLVDVHQKEDHKE-IVINIQRGF--------IESRKKDLML 778
Query: 1289 EEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQ 1322
EE NK L+NE +H KE QYE++KAE V++++
Sbjct: 779 EEKNKKLMNEYDHLKESLFQYERQKAETVVSIKE 812
>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 753
Score = 226 bits (575), Expect = 2e-58
Identities = 115/120 (95%), Positives = 119/120 (99%)
Query: 20 VSSQKQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTED 79
VSSQKQPALKDTSDK+DSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE+
Sbjct: 622 VSSQKQPALKDTSDKDDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEN 681
Query: 80 EFALESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCLYLLDRFAQAVTKDKFALESE 139
EF+LESEIISKLYIPKRKIISPRSI+DVLPPVEEAVDRCLYLLDRFAQ VTKDKFALESE
Sbjct: 682 EFSLESEIISKLYIPKRKIISPRSIKDVLPPVEEAVDRCLYLLDRFAQPVTKDKFALESE 741
Score = 113 bits (283), Expect = 1e-24
Identities = 65/115 (56%), Positives = 80/115 (69%)
Query: 400 VSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEI 459
VSSQKQPALKAT+ +EDS+SNIATEIKDG+KSGTVSSQKQPALK T+D++DSV N ATEI
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 460 KDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATS 514
KD +KS TV + L + D+V+ TE + +S +S P K S
Sbjct: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 109 bits (273), Expect = 2e-23
Identities = 64/115 (55%), Positives = 75/115 (65%)
Query: 363 SGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIA 422
S VSSQKQP KATS K DS NIATEIKDG + GTVSSQKQPALK T+D++DSVSN A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 423 TEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALK 477
TEIKD +KSGTV + L + D+V TE + +SE +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 107 bits (268), Expect = 6e-23
Identities = 63/118 (53%), Positives = 77/118 (65%)
Query: 431 SGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIA 490
S VSSQKQPALKAT+ +EDS+ NIATEIKDG+KS TVSSQKQPALK T+D++DSVS A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 491 TEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATS 548
TEIKD +KSGTV + L + D+ + E + S +S P K S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Score = 104 bits (260), Expect = 5e-22
Identities = 64/122 (52%), Positives = 78/122 (63%)
Query: 635 SGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIA 694
S VSSQKQPALKATS K+DS+SNI TEIKDGQ+SGTVSSQKQ A K TS K DSVSN A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 695 TEIKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKK 754
TEIKD Q GTV + L + D+V+ E + +S +S +K+I +
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704
Query: 755 KV 756
+
Sbjct: 705 SI 706
Score = 104 bits (260), Expect = 5e-22
Identities = 58/93 (62%), Positives = 67/93 (72%)
Query: 604 VSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEI 663
VSS KQPALKATS KE+S+ N+ATE KD Q SGTVSSQKQPALK TSDK DSVSN TEI
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 664 KDGQQSGTVSSQKQLAWKATSVKKDSVSNIATE 696
KD Q+SGTV + + + D+V+ TE
Sbjct: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 680
Score = 100 bits (250), Expect = 8e-21
Identities = 54/71 (76%), Positives = 60/71 (84%)
Query: 264 VSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 323
VSSQKQPA KATS +DS+SNIATEIK+G SGTVSSQKQPA K TSD+ DSVSN ATEI
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 324 KEGQQSGTVSP 334
K+ Q+SGTV P
Sbjct: 648 KDEQKSGTVLP 658
Score = 97.1 bits (240), Expect = 1e-19
Identities = 62/126 (49%), Positives = 76/126 (60%), Gaps = 2/126 (1%)
Query: 465 SETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNIT 524
S VSSQKQPALKAT+ +EDS+S IATEIKDG+KSGTVSS+K+PALK TSD+ DS SN
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 525 REKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLK--ATR 582
E KD + S TV L + D+V E + +S +S P K + R
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIISPR 704
Query: 583 DEKDSL 588
KD L
Sbjct: 705 SIKDVL 710
Score = 86.7 bits (213), Expect = 1e-16
Identities = 51/107 (47%), Positives = 68/107 (63%)
Query: 567 SRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMA 626
S VSS++ P LKAT ++DS+ NIA K G+K+ VSS KQPALK TSDK++SV N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 627 TETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVS 673
TE KDEQ SGTV + L + + D+V+ TE + +S +S
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIIS 691
Score = 82.4 bits (202), Expect = 3e-15
Identities = 53/115 (46%), Positives = 66/115 (57%)
Query: 295 SGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIFKKKVSLLNIA 354
S VSSQKQPA KATS ++DS+SNIATEIK+GQ+SGTVS QKQ A K K S+ N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 355 TRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALK 409
T I KSGTV + + + D+ TE + L+ +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 81.6 bits (200), Expect = 5e-15
Identities = 53/115 (46%), Positives = 63/115 (54%)
Query: 329 SGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIA 388
S VS QKQ A K K+ S+ NIAT I G KSGTVSSQKQP K TSDK DS N A
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 389 TEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK 443
TEIKD + GTV + L + D+V+ TE + +S +S P K
Sbjct: 645 TEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRK 699
Score = 80.5 bits (197), Expect = 1e-14
Identities = 47/93 (50%), Positives = 58/93 (62%)
Query: 706 VSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRI 765
VSSQ+QPALKAT ++DS+SNIA EIKDG+KSGTVS QKQ A K K S+ N AT I
Sbjct: 588 VSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEI 647
Query: 766 TGGWKSGTEYPENLPTLKATIENKNSVLNTATK 798
KSGT P L ++ ++V T+
Sbjct: 648 KDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTE 680
Score = 65.5 bits (158), Expect = 4e-10
Identities = 45/124 (36%), Positives = 61/124 (49%)
Query: 225 LTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSN 284
+ S+ SS++ P T + D S A KD G VSSQKQPA K TSD DSVSN
Sbjct: 583 INSNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSN 642
Query: 285 IATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVIF 344
ATEIK+ SGTV + + D+V+ TE + +S +S K+I
Sbjct: 643 TATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTENEFSLESEIISKLYIPKRKIIS 702
Query: 345 KKKV 348
+ +
Sbjct: 703 PRSI 706
Score = 57.4 bits (137), Expect = 1e-07
Identities = 34/69 (49%), Positives = 41/69 (59%)
Query: 737 SGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTA 796
S VS QKQ A K K+ S+ NIAT I G KSGT + P LK T + +SV NTA
Sbjct: 585 SNPVSSQKQPALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTA 644
Query: 797 TKMKDVQTS 805
T++KD Q S
Sbjct: 645 TEIKDEQKS 653
Score = 32.0 bits (71), Expect = 4.4
Identities = 16/57 (28%), Positives = 29/57 (50%)
Query: 780 PTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQ 836
P LKAT ++S+ N AT++KD Q S + A + + + N ++K++
Sbjct: 594 PALKATSGKEDSISNIATEIKDGQKSGTVSSQKQPALKDTSDKDDSVSNTATEIKDE 650
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sapiens]
Length = 823
Score = 224 bits (572), Expect = 4e-58
Identities = 148/435 (34%), Positives = 248/435 (57%), Gaps = 29/435 (6%)
Query: 903 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---TLELEKELCSLRFAIQQEKK 959
N E++++ + +S RL+++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 960 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ-VSETDE 1018
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N+ +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEE 506
Query: 1019 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNEET 1076
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K NEE
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 1077 LAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSS 1136
+ ET Y +L L ENT L ++L K++ES +RLE +++SY+ RL AA+ H +S +
Sbjct: 567 ITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 1137 KRDQELAFQGTVDKCCHLQ-----ENLNSHVLILSLQLSKAESKFRVLETELHYTGEALK 1191
+R+ +LA + T D ++ + L+ QLS+ + KF L+ + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 1192 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 1247
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 1248 QLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKC 1307
QLDD K D++E + NIQ E K L+LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 1308 QYEKEKAEREVAVRQ 1322
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sapiens]
Length = 823
Score = 224 bits (572), Expect = 4e-58
Identities = 148/435 (34%), Positives = 248/435 (57%), Gaps = 29/435 (6%)
Query: 903 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---TLELEKELCSLRFAIQQEKK 959
N E++++ + +S RL+++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 960 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ-VSETDE 1018
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N+ +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEE 506
Query: 1019 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNEET 1076
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K NEE
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 1077 LAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSS 1136
+ ET Y +L L ENT L ++L K++ES +RLE +++SY+ RL AA+ H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 1137 KRDQELAFQGTVDKCCHLQ-----ENLNSHVLILSLQLSKAESKFRVLETELHYTGEALK 1191
+R+ +LA + T D ++ + L+ QLS+ + KF L+ + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 1192 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 1247
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 1248 QLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKC 1307
QLDD K D++E + NIQ E K L+LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 1308 QYEKEKAEREVAVRQ 1322
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 224 bits (572), Expect = 4e-58
Identities = 148/435 (34%), Positives = 248/435 (57%), Gaps = 29/435 (6%)
Query: 903 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---TLELEKELCSLRFAIQQEKK 959
N E++++ + +S RL+++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 960 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSN-QVSETDE 1018
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEE 506
Query: 1019 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNEET 1076
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K NEE
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 1077 LAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSS 1136
+ ET Y +L L ENT L ++L K++ES +RLE +++SY+ RL AA+ H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 1137 KRDQELAFQGTVDKCCHLQ-----ENLNSHVLILSLQLSKAESKFRVLETELHYTGEALK 1191
+R+ +LA + T D ++ + + L+ QLS+ + KF L+ + T ++L+
Sbjct: 627 ERNLKLALERTRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 1192 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 1247
+K+L E VQ++L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 1248 QLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKC 1307
QLDD K D++E + NIQ E K L+LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLF 797
Query: 1308 QYEKEKAEREVAVRQ 1322
QYE+EK E V++++
Sbjct: 798 QYEREKTEGVVSIKE 812
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 222 bits (565), Expect = 2e-57
Identities = 147/435 (33%), Positives = 245/435 (56%), Gaps = 29/435 (6%)
Query: 903 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHE---TLELEKELCSLRFAIQQEKK 959
N E++++ + +S RL+++ +I + L+ E + C+L+ QE +
Sbjct: 392 NKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLK----QENE 447
Query: 960 KRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSN-QVSETDE 1018
++ NV L++K RE+L E+QY+ E + K ++P ++S E++ KT N N +E
Sbjct: 448 EKTNVNMLYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNWDFHNHEE 506
Query: 1019 KEDLLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNEET 1076
+ L+ EN +++ +IA LR E T+KN NLEK KYLKD +IVK + L+K +K NEE
Sbjct: 507 MKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEM 566
Query: 1077 LAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSS 1136
+ ET Y +L L ENT L ++L K++ES +RLE +++SY+ RL AA+ H +S +
Sbjct: 567 ITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKT 626
Query: 1137 KRDQELAFQGTVDKCCHLQ-----ENLNSHVLILSLQLSKAESKFRVLETELHYTGEALK 1191
+R+ +LA + T D ++ + L+ QLS+ + KF L+ + T ++L+
Sbjct: 627 ERNLKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLR 686
Query: 1192 EKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQ 1247
+K+L E VQ+ L Q Q Q +++++MY++ + K +ER C L+++N L Q
Sbjct: 687 KKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQ 746
Query: 1248 QLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKC 1307
QLDD K D++E + NIQ E K +LEE +K L+NE +H KE
Sbjct: 747 QLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDFVLEEKSKKLMNECDHLKESLF 797
Query: 1308 QYEKEKAEREVAVRQ 1322
QYE+EK E V++++
Sbjct: 798 QYEREKTEVVVSIKE 812
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 213 bits (543), Expect = 8e-55
Identities = 166/524 (31%), Positives = 285/524 (54%), Gaps = 55/524 (10%)
Query: 920 SVLQKRLSEKEE-IKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRIT 978
S+ Q+ L K + +K+ L+++ E A++ E K+R K R+KL+
Sbjct: 346 SIQQQILEHKNKMLKNHLRNDNQETA--------AMKPENLKKR-------KKRKKLKKR 390
Query: 979 EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLMQDEIARLR 1037
+E + E + +K A + + L+ N Q S++ +K+D + N +++ +IA L+
Sbjct: 391 KEGAKAEHN----LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLK 446
Query: 1038 LEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDEN 1095
E IKN +L EKKY+++ + + + + +K+++ NEE + + +A YS QL L EN
Sbjct: 447 EELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAEN 506
Query: 1096 TTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQ 1155
L SKLEK++ + +RLE E++S L A+ ++++ ++D EL D H
Sbjct: 507 ARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEI-LERKDLELVLWRADDVSRH-- 563
Query: 1156 ENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQ 1208
E + S++ +L+ Q+ KA KF L+ +L T +AL+EK L E VQ +LKQ Q
Sbjct: 564 ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQ 623
Query: 1209 SQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 1264
++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN+E ++
Sbjct: 624 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKE-IVI 682
Query: 1265 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQ 1324
NI C +EN + + LLEE NK L+NE N+ KEK QYEKEKAEREV VR+ Q
Sbjct: 683 NIHRDC---LENGKED------LLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQ 733
Query: 1325 QKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTK 1384
++ D L K S +++ L+ +S HC + S+KKL Q+ Q +E ++
Sbjct: 734 EELVDHLKKFSMSESPLEGTS-HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELIS 792
Query: 1385 EMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 1428
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 793 LLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 829
Score = 67.0 bits (162), Expect = 1e-10
Identities = 131/639 (20%), Positives = 266/639 (41%), Gaps = 95/639 (14%)
Query: 798 KMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 857
K+K + AE +L++ASE +Q+RLE EN QP Q SQ+ +
Sbjct: 386 KLKKRKEGAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKK 429
Query: 858 DSLCCN--CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKL 915
D + N K I ++ + K+ L K KK K +TE+ N + +R+ +
Sbjct: 430 DEMFGNFMLKRDIAMLKEELYAIKN-DSLRKEKKYIQEIKSITEINANFEKSVRLNEEMI 488
Query: 916 KNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKL 975
K + ++L++ LK E L +L ++EK + +E + + L
Sbjct: 489 TKKVAQYSQQLND-------LKAENARLNSKL-------EKEKHNKERLEAEVESLHSNL 534
Query: 976 RITEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENRLMQDE 1032
+Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R+ +
Sbjct: 535 ATAINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNT 593
Query: 1033 I-ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAA 1090
+ +LR +D ++ + L + ++ D + + + +++++ E +++I +
Sbjct: 594 LKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEER 653
Query: 1091 LTD---ENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 1147
+ EN L +LE R+ G E + +R L + + +R++EL
Sbjct: 654 IRQRELENLLLERQLEDARKEGDNKEIVINIHR----DCLENGKEDLLEERNKEL----- 704
Query: 1148 VDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQK 1207
+++ +L+E L L + KAE + V E + E L + F +S L+
Sbjct: 705 MNEYNYLKEKL------LQYEKEKAEREVIVREFQ-----EELVDHLKKFSMSESPLEGT 753
Query: 1208 QSQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 1264
++++ + S + I EK E F ++ + LL D R K N+E
Sbjct: 754 SHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--NRE---- 807
Query: 1265 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQ 1324
L+ E ++ LE ML N ++ + ++ ++L+
Sbjct: 808 ------------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLK 855
Query: 1325 QKQDDVLNKRSA--TKALLDASSRHCIYLE----NGMQDSRKKLDQMRSQFQEIQDQLTA 1378
QK DD++ ++ A +K + A ++ E +Q+ +KL++ + +E
Sbjct: 856 QKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE------K 909
Query: 1379 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKI 1417
+ ME D +L ++ ++ + IE+ E+I
Sbjct: 910 VLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 948
Score = 35.0 bits (79), Expect = 0.52
Identities = 39/202 (19%), Positives = 89/202 (44%), Gaps = 26/202 (12%)
Query: 840 RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTE 899
+ DD++ + VS S C N L +E+ ++ + + K+++ C++L +
Sbjct: 855 KQKFDDLMAEKEAVS----SKCVN------LAKDNEVLHQELLSMGKVQEK---CEKLEK 901
Query: 900 LKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKK 959
K + L K+ LK L + +E KS+L ++ ++L + Q E +
Sbjct: 902 DK----KMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYE 957
Query: 960 KRR---NVEELHQKVREKLRITEEQYRIEA------DVTKPIKPALKSAEVELKTGGNNS 1010
K+ N + +++L + + + + DVT ++ ++ V LK + S
Sbjct: 958 KQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMS 1017
Query: 1011 NQVSETDEKEDLLHENRLMQDE 1032
+++++D+K ++ M+ E
Sbjct: 1018 EKITKSDKKIAVISTKLFMEKE 1039
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 213 bits (543), Expect = 8e-55
Identities = 166/524 (31%), Positives = 285/524 (54%), Gaps = 55/524 (10%)
Query: 920 SVLQKRLSEKEE-IKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRIT 978
S+ Q+ L K + +K+ L+++ E A++ E K+R K R+KL+
Sbjct: 375 SIQQQILEHKNKMLKNHLRNDNQETA--------AMKPENLKKR-------KKRKKLKKR 419
Query: 979 EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLMQDEIARLR 1037
+E + E + +K A + + L+ N Q S++ +K+D + N +++ +IA L+
Sbjct: 420 KEGAKAEHN----LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLK 475
Query: 1038 LEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDEN 1095
E IKN +L EKKY+++ + + + + +K+++ NEE + + +A YS QL L EN
Sbjct: 476 EELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAEN 535
Query: 1096 TTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQ 1155
L SKLEK++ + +RLE E++S L A+ ++++ ++D EL D H
Sbjct: 536 ARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEI-LERKDLELVLWRADDVSRH-- 592
Query: 1156 ENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQ 1208
E + S++ +L+ Q+ KA KF L+ +L T +AL+EK L E VQ +LKQ Q
Sbjct: 593 ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQ 652
Query: 1209 SQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 1264
++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN+E ++
Sbjct: 653 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKE-IVI 711
Query: 1265 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQ 1324
NI C +EN + + LLEE NK L+NE N+ KEK QYEKEKAEREV VR+ Q
Sbjct: 712 NIHRDC---LENGKED------LLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQ 762
Query: 1325 QKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTK 1384
++ D L K S +++ L+ +S HC + S+KKL Q+ Q +E ++
Sbjct: 763 EELVDHLKKFSMSESPLEGTS-HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELIS 821
Query: 1385 EMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 1428
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 822 LLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 858
Score = 67.0 bits (162), Expect = 1e-10
Identities = 131/639 (20%), Positives = 266/639 (41%), Gaps = 95/639 (14%)
Query: 798 KMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 857
K+K + AE +L++ASE +Q+RLE EN QP Q SQ+ +
Sbjct: 415 KLKKRKEGAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKK 458
Query: 858 DSLCCN--CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKL 915
D + N K I ++ + K+ L K KK K +TE+ N + +R+ +
Sbjct: 459 DEMFGNFMLKRDIAMLKEELYAIKN-DSLRKEKKYIQEIKSITEINANFEKSVRLNEEMI 517
Query: 916 KNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKL 975
K + ++L++ LK E L +L ++EK + +E + + L
Sbjct: 518 TKKVAQYSQQLND-------LKAENARLNSKL-------EKEKHNKERLEAEVESLHSNL 563
Query: 976 RITEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENRLMQDE 1032
+Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R+ +
Sbjct: 564 ATAINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNT 622
Query: 1033 I-ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAA 1090
+ +LR +D ++ + L + ++ D + + + +++++ E +++I +
Sbjct: 623 LKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEER 682
Query: 1091 LTD---ENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 1147
+ EN L +LE R+ G E + +R L + + +R++EL
Sbjct: 683 IRQRELENLLLERQLEDARKEGDNKEIVINIHR----DCLENGKEDLLEERNKEL----- 733
Query: 1148 VDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQK 1207
+++ +L+E L L + KAE + V E + E L + F +S L+
Sbjct: 734 MNEYNYLKEKL------LQYEKEKAEREVIVREFQ-----EELVDHLKKFSMSESPLEGT 782
Query: 1208 QSQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 1264
++++ + S + I EK E F ++ + LL D R K N+E
Sbjct: 783 SHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--NRE---- 836
Query: 1265 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQ 1324
L+ E ++ LE ML N ++ + ++ ++L+
Sbjct: 837 ------------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLK 884
Query: 1325 QKQDDVLNKRSA--TKALLDASSRHCIYLE----NGMQDSRKKLDQMRSQFQEIQDQLTA 1378
QK DD++ ++ A +K + A ++ E +Q+ +KL++ + +E
Sbjct: 885 QKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE------K 938
Query: 1379 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKI 1417
+ ME D +L ++ ++ + IE+ E+I
Sbjct: 939 VLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 977
Score = 35.0 bits (79), Expect = 0.52
Identities = 39/202 (19%), Positives = 89/202 (44%), Gaps = 26/202 (12%)
Query: 840 RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTE 899
+ DD++ + VS S C N L +E+ ++ + + K+++ C++L +
Sbjct: 884 KQKFDDLMAEKEAVS----SKCVN------LAKDNEVLHQELLSMGKVQEK---CEKLEK 930
Query: 900 LKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKK 959
K + L K+ LK L + +E KS+L ++ ++L + Q E +
Sbjct: 931 DK----KMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYE 986
Query: 960 KRR---NVEELHQKVREKLRITEEQYRIEA------DVTKPIKPALKSAEVELKTGGNNS 1010
K+ N + +++L + + + + DVT ++ ++ V LK + S
Sbjct: 987 KQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMS 1046
Query: 1011 NQVSETDEKEDLLHENRLMQDE 1032
+++++D+K ++ M+ E
Sbjct: 1047 EKITKSDKKIAVISTKLFMEKE 1068
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 213 bits (543), Expect = 8e-55
Identities = 166/524 (31%), Positives = 285/524 (54%), Gaps = 55/524 (10%)
Query: 920 SVLQKRLSEKEE-IKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRIT 978
S+ Q+ L K + +K+ L+++ E A++ E K+R K R+KL+
Sbjct: 375 SIQQQILEHKNKMLKNHLRNDNQETA--------AMKPENLKKR-------KKRKKLKKR 419
Query: 979 EEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLMQDEIARLR 1037
+E + E + +K A + + L+ N Q S++ +K+D + N +++ +IA L+
Sbjct: 420 KEGAKAEHN----LKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLK 475
Query: 1038 LEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDEN 1095
E IKN +L EKKY+++ + + + + +K+++ NEE + + +A YS QL L EN
Sbjct: 476 EELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAEN 535
Query: 1096 TTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQ 1155
L SKLEK++ + +RLE E++S L A+ ++++ ++D EL D H
Sbjct: 536 ARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEI-LERKDLELVLWRADDVSRH-- 592
Query: 1156 ENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQ 1208
E + S++ +L+ Q+ KA KF L+ +L T +AL+EK L E VQ +LKQ Q
Sbjct: 593 ETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQ 652
Query: 1209 SQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 1264
++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN+E ++
Sbjct: 653 HRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKE-IVI 711
Query: 1265 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQ 1324
NI C +EN + + LLEE NK L+NE N+ KEK QYEKEKAEREV VR+ Q
Sbjct: 712 NIHRDC---LENGKED------LLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQ 762
Query: 1325 QKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTK 1384
++ D L K S +++ L+ +S HC + S+KKL Q+ Q +E ++
Sbjct: 763 EELVDHLKKFSMSESPLEGTS-HCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELIS 821
Query: 1385 EMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 1428
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 822 LLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 858
Score = 67.0 bits (162), Expect = 1e-10
Identities = 131/639 (20%), Positives = 266/639 (41%), Gaps = 95/639 (14%)
Query: 798 KMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDG 857
K+K + AE +L++ASE +Q+RLE EN QP Q SQ+ +
Sbjct: 415 KLKKRKEGAKAEHNLKVASEEKQERLERSENKQP----------------QDSQSYGKKK 458
Query: 858 DSLCCN--CKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKL 915
D + N K I ++ + K+ L K KK K +TE+ N + +R+ +
Sbjct: 459 DEMFGNFMLKRDIAMLKEELYAIKN-DSLRKEKKYIQEIKSITEINANFEKSVRLNEEMI 517
Query: 916 KNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKL 975
K + ++L++ LK E L +L ++EK + +E + + L
Sbjct: 518 TKKVAQYSQQLND-------LKAENARLNSKL-------EKEKHNKERLEAEVESLHSNL 563
Query: 976 RITEEQYRIEADVTKPIKPALKSAE--VELKTGGNNSNQVSETDE-KEDLLHENRLMQDE 1032
+Y E K ++ L A+ +T G+N +Q+++ +E + +H+ R+ +
Sbjct: 564 ATAINEYN-EILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNT 622
Query: 1033 I-ARLRLEKDTIKNQNLEKKYLK-DFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAA 1090
+ +LR +D ++ + L + ++ D + + + +++++ E +++I +
Sbjct: 623 LKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEER 682
Query: 1091 LTD---ENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 1147
+ EN L +LE R+ G E + +R L + + +R++EL
Sbjct: 683 IRQRELENLLLERQLEDARKEGDNKEIVINIHR----DCLENGKEDLLEERNKEL----- 733
Query: 1148 VDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQK 1207
+++ +L+E L L + KAE + V E + E L + F +S L+
Sbjct: 734 MNEYNYLKEKL------LQYEKEKAEREVIVREFQ-----EELVDHLKKFSMSESPLEGT 782
Query: 1208 QSQMKDIEKMYKSGYNTMEKCI---EKQERFCQLKKQNMLLQQQLDDARNKADNQEKAIL 1264
++++ + S + I EK E F ++ + LL D R K N+E
Sbjct: 783 SHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKK--NRE---- 836
Query: 1265 NIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQ 1324
L+ E ++ LE ML N ++ + ++ ++L+
Sbjct: 837 ------------LEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLK 884
Query: 1325 QKQDDVLNKRSA--TKALLDASSRHCIYLE----NGMQDSRKKLDQMRSQFQEIQDQLTA 1378
QK DD++ ++ A +K + A ++ E +Q+ +KL++ + +E
Sbjct: 885 QKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEE------K 938
Query: 1379 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKI 1417
+ ME D +L ++ ++ + IE+ E+I
Sbjct: 939 VLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEI 977
Score = 35.0 bits (79), Expect = 0.52
Identities = 39/202 (19%), Positives = 89/202 (44%), Gaps = 26/202 (12%)
Query: 840 RDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTE 899
+ DD++ + VS S C N L +E+ ++ + + K+++ C++L +
Sbjct: 884 KQKFDDLMAEKEAVS----SKCVN------LAKDNEVLHQELLSMGKVQEK---CEKLEK 930
Query: 900 LKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKK 959
K + L K+ LK L + +E KS+L ++ ++L + Q E +
Sbjct: 931 DK----KMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYE 986
Query: 960 KRR---NVEELHQKVREKLRITEEQYRIEA------DVTKPIKPALKSAEVELKTGGNNS 1010
K+ N + +++L + + + + DVT ++ ++ V LK + S
Sbjct: 987 KQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMS 1046
Query: 1011 NQVSETDEKEDLLHENRLMQDE 1032
+++++D+K ++ M+ E
Sbjct: 1047 EKITKSDKKIAVISTKLFMEKE 1068
>gi|169217530 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 121
Score = 209 bits (533), Expect = 1e-53
Identities = 107/116 (92%), Positives = 112/116 (96%)
Query: 1315 EREVAVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQD 1374
E++VAVRQLQQK+DDVLNK SATKALLDASSRHC YLENGMQDSRKKLDQMRSQFQEIQD
Sbjct: 6 EKKVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQD 65
Query: 1375 QLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVFES 1430
QLTATIRCTKEMEGD QKLEVE+VMMRKIIKKQD+QIER EKILQHSSLMLQVFES
Sbjct: 66 QLTATIRCTKEMEGDTQKLEVEHVMMRKIIKKQDDQIERLEKILQHSSLMLQVFES 121
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 203 bits (516), Expect = 1e-51
Identities = 160/530 (30%), Positives = 279/530 (52%), Gaps = 37/530 (6%)
Query: 917 NKASVLQKRLSEKEEIKSQ----LKHETLELEKELCSLRFAIQQEKKK--RRNVEELHQK 970
N +S++ L + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 318 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 377
Query: 971 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 1029
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 378 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 437
Query: 1030 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQ 1087
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ NE+ + +T+A YS Q
Sbjct: 438 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 497
Query: 1088 LAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 1147
L L EN L S+LEK++ + +RLE E++S L A+ ++++ ++D EL
Sbjct: 498 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 556
Query: 1148 VDKCCHLQENLNSHVL-----ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQS 1202
D H + N L +L+ Q+ KA KF L+ +L T +AL+EK L VQ
Sbjct: 557 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 616
Query: 1203 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 1258
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 617 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 676
Query: 1259 QEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREV 1318
+E ++NI C +EN + + LLEE NK L+ E N+ KEK Q EKEKAEREV
Sbjct: 677 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 726
Query: 1319 AVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1378
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 727 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785
Query: 1379 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 1428
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 786 LFELISLLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 828
Score = 63.9 bits (154), Expect = 1e-09
Identities = 152/724 (20%), Positives = 275/724 (37%), Gaps = 181/724 (25%)
Query: 787 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 846
+N+ + +K + AE +L++ASE +Q+RL+ EN QP
Sbjct: 374 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQP--------------- 418
Query: 847 IQSSQTVSEDGDSLCCNC---KNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDN 903
Q SQ+ + D++ N K++ +L + E+ L K KK K +TE+ N
Sbjct: 419 -QDSQSYGKKKDAMYGNFMLKKDIAML--KEELYAIKNDSLRKEKKYIQEIKSITEINAN 475
Query: 904 HCEQLRVKIRKLKNKASVLQKRL----SEKEEIKSQL---KHETLELEKELCSLRFA--- 953
+ +R+ + + + ++L +E + S+L KH LE E+ SL +
Sbjct: 476 FEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLAT 535
Query: 954 -----------------------IQQEKKKRRNVEELHQK-----------------VRE 973
+ + +K N+ +L K ++
Sbjct: 536 AINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKG 595
Query: 974 KLRITEEQYRIEADVTKPIKPALKSAEVELK----TGGNNSNQVSETDEKEDLLHENRLM 1029
KLR T + R + ++ L+ A+ +K N + S++ K++ L E R+
Sbjct: 596 KLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSL-EERIR 654
Query: 1030 QDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLA 1089
Q E+ L LE+ +K + EIV H D L+ +E L E +
Sbjct: 655 QQELENLLLERQL----EDARKEGDNKEIVINIHRD---CLENGKEDLLEE------RNK 701
Query: 1090 ALTDENTTLRSKL---EKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQG 1146
L E L+ KL EK++ + + E Q L DH ++ S E +G
Sbjct: 702 ELMKEYNYLKEKLLQCEKEKAEREVIVREFQE-------ELVDHLKTFSI---SESPLEG 751
Query: 1147 TVDKCCHLQENLNSHVLILSLQLSKAES-----KFRVLETELHYTGEALKEKALVFEH-- 1199
T +L E S + +++ E K L + L+YT + +++K E
Sbjct: 752 TSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEA 811
Query: 1200 -----------------------VQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFC 1236
+L Q +M + K K +N + E C
Sbjct: 812 TGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSEC 871
Query: 1237 -QLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKML 1295
L K N +L Q+L R N+Q +C K LE+D KML
Sbjct: 872 VNLAKDNEVLHQELLSMR----------------------NVQEKCEK----LEKDKKML 905
Query: 1296 VNELNHSKE----------KKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDA-- 1343
E+ + K K +Y+ E ER AV+++++ ++ L K++ + L+
Sbjct: 906 EEEVLNLKTHMEKDMVELGKLQEYKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLN 963
Query: 1344 --SSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMR 1401
++ E ++D K +M++ ++E+ +L + E A ++ N M +
Sbjct: 964 KDNTASLKKKELTLKDVECKFSKMKTAYEEVTTEL------EEFKEAFAGAVKANNSMSK 1017
Query: 1402 KIIK 1405
K++K
Sbjct: 1018 KLMK 1021
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 203 bits (516), Expect = 1e-51
Identities = 160/530 (30%), Positives = 279/530 (52%), Gaps = 37/530 (6%)
Query: 917 NKASVLQKRLSEKEEIKSQ----LKHETLELEKELCSLRFAIQQEKKK--RRNVEELHQK 970
N +S++ L + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 211 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 270
Query: 971 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 1029
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 271 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 330
Query: 1030 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQ 1087
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ NE+ + +T+A YS Q
Sbjct: 331 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 390
Query: 1088 LAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 1147
L L EN L S+LEK++ + +RLE E++S L A+ ++++ ++D EL
Sbjct: 391 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 449
Query: 1148 VDKCCHLQENLNSHVL-----ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQS 1202
D H + N L +L+ Q+ KA KF L+ +L T +AL+EK L VQ
Sbjct: 450 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 509
Query: 1203 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 1258
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 510 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 569
Query: 1259 QEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREV 1318
+E ++NI C +EN + + LLEE NK L+ E N+ KEK Q EKEKAEREV
Sbjct: 570 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 619
Query: 1319 AVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1378
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 620 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 678
Query: 1379 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 1428
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 679 LFELISLLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 721
Score = 63.9 bits (154), Expect = 1e-09
Identities = 152/724 (20%), Positives = 275/724 (37%), Gaps = 181/724 (25%)
Query: 787 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 846
+N+ + +K + AE +L++ASE +Q+RL+ EN QP
Sbjct: 267 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQP--------------- 311
Query: 847 IQSSQTVSEDGDSLCCNC---KNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDN 903
Q SQ+ + D++ N K++ +L + E+ L K KK K +TE+ N
Sbjct: 312 -QDSQSYGKKKDAMYGNFMLKKDIAML--KEELYAIKNDSLRKEKKYIQEIKSITEINAN 368
Query: 904 HCEQLRVKIRKLKNKASVLQKRL----SEKEEIKSQL---KHETLELEKELCSLRFA--- 953
+ +R+ + + + ++L +E + S+L KH LE E+ SL +
Sbjct: 369 FEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLAT 428
Query: 954 -----------------------IQQEKKKRRNVEELHQK-----------------VRE 973
+ + +K N+ +L K ++
Sbjct: 429 AINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKG 488
Query: 974 KLRITEEQYRIEADVTKPIKPALKSAEVELK----TGGNNSNQVSETDEKEDLLHENRLM 1029
KLR T + R + ++ L+ A+ +K N + S++ K++ L E R+
Sbjct: 489 KLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSL-EERIR 547
Query: 1030 QDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLA 1089
Q E+ L LE+ +K + EIV H D L+ +E L E +
Sbjct: 548 QQELENLLLERQL----EDARKEGDNKEIVINIHRD---CLENGKEDLLEE------RNK 594
Query: 1090 ALTDENTTLRSKL---EKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQG 1146
L E L+ KL EK++ + + E Q L DH ++ S E +G
Sbjct: 595 ELMKEYNYLKEKLLQCEKEKAEREVIVREFQE-------ELVDHLKTFSI---SESPLEG 644
Query: 1147 TVDKCCHLQENLNSHVLILSLQLSKAES-----KFRVLETELHYTGEALKEKALVFEH-- 1199
T +L E S + +++ E K L + L+YT + +++K E
Sbjct: 645 TSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEA 704
Query: 1200 -----------------------VQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFC 1236
+L Q +M + K K +N + E C
Sbjct: 705 TGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSEC 764
Query: 1237 -QLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKML 1295
L K N +L Q+L R N+Q +C K LE+D KML
Sbjct: 765 VNLAKDNEVLHQELLSMR----------------------NVQEKCEK----LEKDKKML 798
Query: 1296 VNELNHSKE----------KKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDA-- 1343
E+ + K K +Y+ E ER AV+++++ ++ L K++ + L+
Sbjct: 799 EEEVLNLKTHMEKDMVELGKLQEYKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLN 856
Query: 1344 --SSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMR 1401
++ E ++D K +M++ ++E+ +L + E A ++ N M +
Sbjct: 857 KDNTASLKKKELTLKDVECKFSKMKTAYEEVTTEL------EEFKEAFAGAVKANNSMSK 910
Query: 1402 KIIK 1405
K++K
Sbjct: 911 KLMK 914
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 203 bits (516), Expect = 1e-51
Identities = 160/530 (30%), Positives = 279/530 (52%), Gaps = 37/530 (6%)
Query: 917 NKASVLQKRLSEKEEIKSQ----LKHETLELEKELCSLRFAIQQEKKK--RRNVEELHQK 970
N +S++ L + I SQ E L +L S+R I + K K + ++ +Q+
Sbjct: 318 NLSSIVTLLLQQNIRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQE 377
Query: 971 VREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSET-DEKEDLLHENRLM 1029
++ + A +K A + + L+ N Q S++ +K+D ++ N ++
Sbjct: 378 TAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFML 437
Query: 1030 QDEIARLRLEKDTIKNQNL--EKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQ 1087
+ +IA L+ E IKN +L EKKY+++ + + + + +K+++ NE+ + +T+A YS Q
Sbjct: 438 KKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ 497
Query: 1088 LAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGT 1147
L L EN L S+LEK++ + +RLE E++S L A+ ++++ ++D EL
Sbjct: 498 LNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEI-VERKDLELVLWRA 556
Query: 1148 VDKCCHLQENLNSHVL-----ILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHVQS 1202
D H + N L +L+ Q+ KA KF L+ +L T +AL+EK L VQ
Sbjct: 557 DDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL 616
Query: 1203 ELKQKQSQMKDIEKMYKSGYNTMEKCIEKQ----ERFCQLKKQNMLLQQQLDDARNKADN 1258
+L+Q Q ++K++++M+ +G + I KQ ER Q + +N+LL++QL+DAR + DN
Sbjct: 617 DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDN 676
Query: 1259 QEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREV 1318
+E ++NI C +EN + + LLEE NK L+ E N+ KEK Q EKEKAEREV
Sbjct: 677 KE-IVINIHRDC---LENGKED------LLEERNKELMKEYNYLKEKLLQCEKEKAEREV 726
Query: 1319 AVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTA 1378
VR+ Q++ D L S +++ L+ +S HC N S+KKL Q+ Q +E ++
Sbjct: 727 IVREFQEELVDHLKTFSISESPLEGTS-HCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785
Query: 1379 TIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQVF 1428
+ A ++ +N ++ +E+ ++K L+ + ML F
Sbjct: 786 LFELISLLNYTADQIRKKN-------RELEEEATGYKKCLEMTINMLNAF 828
Score = 63.9 bits (154), Expect = 1e-09
Identities = 152/724 (20%), Positives = 275/724 (37%), Gaps = 181/724 (25%)
Query: 787 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 846
+N+ + +K + AE +L++ASE +Q+RL+ EN QP
Sbjct: 374 DNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQP--------------- 418
Query: 847 IQSSQTVSEDGDSLCCNC---KNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKDN 903
Q SQ+ + D++ N K++ +L + E+ L K KK K +TE+ N
Sbjct: 419 -QDSQSYGKKKDAMYGNFMLKKDIAML--KEELYAIKNDSLRKEKKYIQEIKSITEINAN 475
Query: 904 HCEQLRVKIRKLKNKASVLQKRL----SEKEEIKSQL---KHETLELEKELCSLRFA--- 953
+ +R+ + + + ++L +E + S+L KH LE E+ SL +
Sbjct: 476 FEKSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLAT 535
Query: 954 -----------------------IQQEKKKRRNVEELHQK-----------------VRE 973
+ + +K N+ +L K ++
Sbjct: 536 AINEYNEIVERKDLELVLWRADDVSRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKG 595
Query: 974 KLRITEEQYRIEADVTKPIKPALKSAEVELK----TGGNNSNQVSETDEKEDLLHENRLM 1029
KLR T + R + ++ L+ A+ +K N + S++ K++ L E R+
Sbjct: 596 KLRETRDALREKTLALGSVQLDLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSL-EERIR 654
Query: 1030 QDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLA 1089
Q E+ L LE+ +K + EIV H D L+ +E L E +
Sbjct: 655 QQELENLLLERQL----EDARKEGDNKEIVINIHRD---CLENGKEDLLEE------RNK 701
Query: 1090 ALTDENTTLRSKL---EKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQG 1146
L E L+ KL EK++ + + E Q L DH ++ S E +G
Sbjct: 702 ELMKEYNYLKEKLLQCEKEKAEREVIVREFQE-------ELVDHLKTFSI---SESPLEG 751
Query: 1147 TVDKCCHLQENLNSHVLILSLQLSKAES-----KFRVLETELHYTGEALKEKALVFEH-- 1199
T +L E S + +++ E K L + L+YT + +++K E
Sbjct: 752 TSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRKLFELISLLNYTADQIRKKNRELEEEA 811
Query: 1200 -----------------------VQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFC 1236
+L Q +M + K K +N + E C
Sbjct: 812 TGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSEC 871
Query: 1237 -QLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKML 1295
L K N +L Q+L R N+Q +C K LE+D KML
Sbjct: 872 VNLAKDNEVLHQELLSMR----------------------NVQEKCEK----LEKDKKML 905
Query: 1296 VNELNHSKE----------KKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLDA-- 1343
E+ + K K +Y+ E ER AV+++++ ++ L K++ + L+
Sbjct: 906 EEEVLNLKTHMEKDMVELGKLQEYKSELDER--AVQEIEKLEEIHLQKQAEYEKQLEQLN 963
Query: 1344 --SSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMMR 1401
++ E ++D K +M++ ++E+ +L + E A ++ N M +
Sbjct: 964 KDNTASLKKKELTLKDVECKFSKMKTAYEEVTTEL------EEFKEAFAGAVKANNSMSK 1017
Query: 1402 KIIK 1405
K++K
Sbjct: 1018 KLMK 1021
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 129 bits (325), Expect = 2e-29
Identities = 114/413 (27%), Positives = 203/413 (49%), Gaps = 41/413 (9%)
Query: 1018 EKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNEETL 1077
E ED + + + + LR E+ E++ + E + + ++ K + L
Sbjct: 129 EVEDPAVKGAVQRKNVQTLRAEQTLPVALEEEQERCERSEKKQSQVKEGNNTNKSEKIQL 188
Query: 1078 AETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSK 1137
+E + C+S AA +L KQR+ G+ T Q + +L +HD+ +
Sbjct: 189 SENV-CHSTSSAAA--------DRLTKQRKVGK---TYPQQFPKKLKK---EHDREELER 233
Query: 1138 RDQELAFQGTVDKCCHLQENLNSHVLILSLQLSKAESKFRVLETELHYTGEALKEKALVF 1197
++++ ++ V+ + L V L ++L + + L Y+ ++K + F
Sbjct: 234 KEKQ--YKKEVEA-----KQLEPTVQSLDMKLKTTRNTPNQINQSLRYS----QKKVIGF 282
Query: 1198 EHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK----QERFCQLKKQNMLLQQQLDDAR 1253
+ ++L Q Q Q+K++++MY++ + K +ER CQL+ +N ++QQLDD
Sbjct: 283 RNSPNDLSQTQQQIKEMKEMYENAEAKVNNSTGKWSCVEERICQLQHENPCIEQQLDDVH 342
Query: 1254 NKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELNHSKEKKCQYEKEK 1313
K D++E + NIQ E K L+LEE NK L+NE +H KE QYE+EK
Sbjct: 343 QKEDHKE-IVTNIQRGF--------IESGKKDLMLEEKNKKLMNECDHLKESLFQYEREK 393
Query: 1314 AEREVAVRQLQQKQDDVLNKRSATKALLDASSRHCIYLENGMQDSRKKLDQMRSQFQEIQ 1373
AER V VRQLQQ+ D L K + ++ L+ S + I L+ Q +KKL Q+ SQF +
Sbjct: 394 AERVVVVRQLQQEAADSLKKLTMLESPLEGISHYHINLDE-TQVPKKKLFQVESQFDDFM 452
Query: 1374 DQLTATIRCTKEMEGDAQKLEVENVMMRKIIKKQDEQIERFEKILQHSSLMLQ 1426
+ A + + Q + E + M+K ++++ E++E +K+L+ L L+
Sbjct: 453 AEKEAVSSKCVNLAKEIQVFQQELLSMKK-VQQECEKLEEDKKMLEEEILNLK 504
Score = 46.2 bits (108), Expect = 2e-04
Identities = 106/495 (21%), Positives = 202/495 (40%), Gaps = 70/495 (14%)
Query: 764 RITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRL 823
RI G G P P+LK + E ++ + A + K+VQT AEQ L +A E EQ+R
Sbjct: 108 RIVNGKGKGP--PAKHPSLKPSTEVEDPAVKGAVQRKNVQTLR-AEQTLPVALEEEQERC 164
Query: 824 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 883
E E Q QVK + + + IQ S+ V S + L Q
Sbjct: 165 ERSEKKQSQVKE--GNNTNKSEKIQLSENVCHSTSSAAAD-----RLTKQR--------- 208
Query: 884 LLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKS-QLKHETLE 942
K+ KT+ +Q K++K ++ + +K K+E+++ QL+
Sbjct: 209 --KVGKTY-------------PQQFPKKLKKEHDREELERKEKQYKKEVEAKQLEPTVQS 253
Query: 943 LEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVE 1002
L+ +L + R Q + R QK R + K +K ++AE +
Sbjct: 254 LDMKLKTTRNTPNQINQSLR----YSQKKVIGFRNSPNDLSQTQQQIKEMKEMYENAEAK 309
Query: 1003 LKTGGNNSNQVSETDEKE-DLLHENRLMQDEIARLRLEKDTIK-NQNLEKKYL----KDF 1056
+ N++ + S +E+ L HEN ++ ++ + ++D + N+++ ++ KD
Sbjct: 310 V---NNSTGKWSCVEERICQLQHENPCIEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDL 366
Query: 1057 EIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEM 1116
+ E+ K L + L E++ Y + A E + +L+++ + T +
Sbjct: 367 ML-----EEKNKKLMNECDHLKESLFQYEREKA----ERVVVVRQLQQEAADSLKKLTML 417
Query: 1117 QSYRCRLNAALCDHDQSHSSKR---------DQELAFQGTV-DKCCHLQENLNSHVLILS 1166
+S ++ + D++ K+ D +A + V KC +L + + L
Sbjct: 418 ESPLEGISHYHINLDETQVPKKKLFQVESQFDDFMAEKEAVSSKCVNLAKEIQVFQQEL- 476
Query: 1167 LQLSKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTME 1226
L + K + + LE + E + E+ EL + Q ++++ +E
Sbjct: 477 LSMKKVQQECEKLEEDKKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLE 536
Query: 1227 KCIEKQERFCQLKKQ 1241
+ I QE+ + KKQ
Sbjct: 537 E-IHLQEQ-AEHKKQ 549
Score = 45.4 bits (106), Expect = 4e-04
Identities = 102/506 (20%), Positives = 185/506 (36%), Gaps = 74/506 (14%)
Query: 472 KQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGE 531
K P+LK +T+ ED A + K+ + + R + L +E+ + EKK +
Sbjct: 120 KHPSLKPSTEVEDPAVKGAVQRKNVQ-----TLRAEQTLPVALEEEQERCERS-EKKQSQ 173
Query: 532 ISRTVSSQKPPALKATSDEEDSVLSIAREE--KDGEKSRTVSSEQPPGLKATRDEKDSLL 589
+ ++ K ++ + + S S A + K + +T + P LK D ++
Sbjct: 174 VKEGNNTNKSEKIQLSENVCHSTSSAAADRLTKQRKVGKTYPQQFPKKLKKEHDREELER 233
Query: 590 NIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKAT 649
+ KK E + +P +++ K + N +Q +L+ +
Sbjct: 234 KEKQYKKEVE-----AKQLEPTVQSLDMKLKTTRN-------------TPNQINQSLRYS 275
Query: 650 SDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSV---SNIATEIKDGQIRGTV 706
K N P ++ QQ + K++ A + +S S + I Q
Sbjct: 276 QKKVIGFRNSPNDLSQTQQQ--IKEMKEMYENAEAKVNNSTGKWSCVEERICQLQHENPC 333
Query: 707 SSQRQPALKATGDEKDSVSNIARE-IKDGEKSGTVSPQKQSAQKVIFKKKVSLLNIATRI 765
Q+ + D K+ V+NI R I+ G+K ++ +K L+N +
Sbjct: 334 IEQQLDDVHQKEDHKEIVTNIQRGFIESGKKD-----------LMLEEKNKKLMNECDHL 382
Query: 766 TGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEE 825
+S +Y E V+ ++ S LE EG
Sbjct: 383 K---ESLFQYER---------EKAERVVVVRQLQQEAADSLKKLTMLESPLEGISHYHIN 430
Query: 826 YENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLL 885
+ Q K DD + + VS S C N I + Q LL
Sbjct: 431 LDETQVPKKKLFQVESQFDDFMAEKEAVS----SKCVNLAKEIQVFQQE---------LL 477
Query: 886 KIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEK 945
+KK C++L E K + L +I LK LS+ +E KS+L ++ +
Sbjct: 478 SMKKVQQECEKLEEDK----KMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVE 533
Query: 946 ELCSLRFAIQQEKKKRRNVEELHQKV 971
+L + Q E KK+ +E+L++ +
Sbjct: 534 KLEEIHLQEQAEHKKQ--LEQLNKDI 557
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.123 0.323
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,224,350
Number of Sequences: 37866
Number of extensions: 2296592
Number of successful extensions: 20581
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 279
Number of HSP's successfully gapped in prelim test: 1274
Number of HSP's that attempted gapping in prelim test: 10811
Number of HSP's gapped (non-prelim): 6492
length of query: 1430
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1315
effective length of database: 13,892,928
effective search space: 18269200320
effective search space used: 18269200320
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.