BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo sapiens] (179 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|169164209 PREDICTED: hypothetical protein [Homo sapiens] 365 e-101 gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo ... 365 e-101 gi|169163999 PREDICTED: hypothetical protein [Homo sapiens] 169 1e-42 gi|110832843 TBP-associated factor 4 [Homo sapiens] 56 2e-08 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 56 2e-08 gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens] 54 7e-08 gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens] 54 7e-08 gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo sa... 52 2e-07 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 52 4e-07 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 51 5e-07 gi|18079216 CASK interacting protein 1 [Homo sapiens] 50 8e-07 gi|56549694 enabled homolog isoform a [Homo sapiens] 50 1e-06 gi|39930375 enabled homolog isoform b [Homo sapiens] 50 1e-06 gi|33356148 formin-like 1 [Homo sapiens] 50 1e-06 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 49 2e-06 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 49 2e-06 gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo ... 49 3e-06 gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo ... 49 3e-06 gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo ... 49 3e-06 gi|150417989 cyclin K isoform 1 [Homo sapiens] 48 5e-06 gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 47 9e-06 gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 47 9e-06 gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 47 9e-06 gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 47 9e-06 gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 47 9e-06 gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] 47 9e-06 gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 47 9e-06 gi|210032580 SET domain containing 1B [Homo sapiens] 47 9e-06 gi|157168329 formin 1 [Homo sapiens] 47 1e-05 gi|210031233 PR domain containing 6 [Homo sapiens] 47 1e-05 >gi|169164209 PREDICTED: hypothetical protein [Homo sapiens] Length = 179 Score = 365 bits (937), Expect = e-101 Identities = 179/179 (100%), Positives = 179/179 (100%) Query: 1 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS Sbjct: 1 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60 Query: 61 HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA 120 HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA Sbjct: 61 HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA 120 Query: 121 AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG 179 AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG Sbjct: 121 AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG 179 >gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo sapiens] Length = 179 Score = 365 bits (937), Expect = e-101 Identities = 179/179 (100%), Positives = 179/179 (100%) Query: 1 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS Sbjct: 1 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60 Query: 61 HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA 120 HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA Sbjct: 61 HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA 120 Query: 121 AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG 179 AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG Sbjct: 121 AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG 179 >gi|169163999 PREDICTED: hypothetical protein [Homo sapiens] Length = 84 Score = 169 bits (428), Expect = 1e-42 Identities = 84/84 (100%), Positives = 84/84 (100%) Query: 96 MGLGRTQRAARVAVSRALAGTVAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGC 155 MGLGRTQRAARVAVSRALAGTVAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGC Sbjct: 1 MGLGRTQRAARVAVSRALAGTVAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGC 60 Query: 156 SLGRVSPDRTPGKGSKGMEPPHTG 179 SLGRVSPDRTPGKGSKGMEPPHTG Sbjct: 61 SLGRVSPDRTPGKGSKGMEPPHTG 84 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 55.8 bits (133), Expect = 2e-08 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 11/98 (11%) Query: 5 SAARAAPSPILP-PPPDLPPTPTRRAPLIGC--PPSPARPAPSASPSPSR-AAGPFLPPS 60 S P+ +LP P P P T + P +G PP+PA P+P A+P+P+ AA P PP Sbjct: 216 SLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP 275 Query: 61 HASTSSRSP-----PPRARRTEPAVPPSCGSGPGAAGA 93 +T +R P PP A P PP+ G+AGA Sbjct: 276 APATLARPPGHPAGPPTAAPAVP--PPAAAQNGGSAGA 311 Score = 45.1 bits (105), Expect = 3e-05 Identities = 42/118 (35%), Positives = 50/118 (42%), Gaps = 11/118 (9%) Query: 11 PSPILP--PPPDLPPTPTRRAPLIG----CPPSPARPAPSASPSPSRAAGPFLPPSHAST 64 PSP P P PP R P G C P PA A +A P P+ AGP P A+ Sbjct: 108 PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA-PAGPAKPAGPAAL 166 Query: 65 SSRSPPPRARRTEPAVPPSCG--SGPGAAGALR--MGLGRTQRAARVAVSRALAGTVA 118 ++R+ P P P G +GPGAA L L + AA AVS G A Sbjct: 167 AARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAA 224 Score = 44.7 bits (104), Expect = 4e-05 Identities = 38/101 (37%), Positives = 43/101 (42%), Gaps = 8/101 (7%) Query: 4 ASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS 63 A+ A AP PPP P P PPSP RP A P+P A PP S Sbjct: 76 AAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP--PAAKLRPPPEGS 133 Query: 64 TSSRSPPPRARRT----EPA-VPPSCGSGPGAAGALRMGLG 99 S +P P A EPA P+ +GP AA A R G G Sbjct: 134 AGSCAPVPAAAAVAAGPEPAPAGPAKPAGP-AALAARAGPG 173 Score = 40.8 bits (94), Expect = 6e-04 Identities = 41/129 (31%), Positives = 50/129 (38%), Gaps = 17/129 (13%) Query: 2 AGASAARAAPSPILPP--------PPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAA 53 A A A AAPSP P PP PP P A G P P AP A P P+ A Sbjct: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP-AVPPPAAA- 303 Query: 54 GPFLPPSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRAL 113 + ++ +P P PA S GPGAA A + + RV + Sbjct: 304 ------QNGGSAGAAPAPAPAAGGPA-GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPP 356 Query: 114 AGTVAAAAG 122 A AA+G Sbjct: 357 AAQTLAASG 365 Score = 40.4 bits (93), Expect = 8e-04 Identities = 48/175 (27%), Positives = 58/175 (33%), Gaps = 59/175 (33%) Query: 4 ASAARAAPSPILPPPPDLPPT----------PTRRAPLIGCP--------------PSPA 39 A+ A AAP+ PPPP P T P AP + P P+PA Sbjct: 259 AAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA 318 Query: 40 RPAP---SASPSPSRAAGPFLPPSHASTSSR---SPPPRARR------------------ 75 P S P P AA P A + R + PP A+ Sbjct: 319 AGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPT 378 Query: 76 ------TEPAVPPSCGSGP-----GAAGALRMGLGRTQRAARVAVSRALAGTVAA 119 + AVPP P GAAGA+ L RT A + L TV A Sbjct: 379 MQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA 433 Score = 30.4 bits (67), Expect = 0.85 Identities = 40/150 (26%), Positives = 50/150 (33%), Gaps = 16/150 (10%) Query: 22 PPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPPRARR------ 75 P TP RA G + S SP+ + AGP P A ++ PPP R Sbjct: 45 PRTPEVRAAAAG---ALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGG 101 Query: 76 TEPAVPPS-------CGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAAGLGARRA 128 + PPS G P AA G A V + A+A A A+ A Sbjct: 102 PQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPA 161 Query: 129 RRLHLRGQIGVRRVAGTPEARGRGDGCSLG 158 L + G G G G G G Sbjct: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAG 191 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 55.8 bits (133), Expect = 2e-08 Identities = 58/182 (31%), Positives = 71/182 (39%), Gaps = 28/182 (15%) Query: 2 AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH 61 A +AA AA +P P P P R APL PP+PA P A P+ R A PP+ Sbjct: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAP---PPAV 204 Query: 62 ASTSSRSPPPRARRTEP---AVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVA 118 A+ PPP P PP P GA+R G AAR R + + Sbjct: 205 AAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAG-----GAARPVSLREVVRYLG 259 Query: 119 AAAGLGARRARRLHLRGQIGVRRVAGTPE----ARGRGDGCSLGRVSPDRTPGKGSKGME 174 + G G R R RV G E ARGR + LG ++ P G Sbjct: 260 GSGGAGGRLTR----------GRVQGLLEEEAAARGRLERTRLGALA---LPRGDRPGRA 306 Query: 175 PP 176 PP Sbjct: 307 PP 308 Score = 47.0 bits (110), Expect = 9e-06 Identities = 34/96 (35%), Positives = 43/96 (44%), Gaps = 11/96 (11%) Query: 5 SAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPA-RPAPSASPSPSRAAGPFLPPSHAS 63 +AAR P P P PP R AP +P PAP P+P AA P P A+ Sbjct: 95 NAARVQP-PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAA 153 Query: 64 TSSRSPP--------PRARRTEP-AVPPSCGSGPGA 90 ++ +PP PRA+R P A PP + P A Sbjct: 154 AAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPA 189 Score = 41.6 bits (96), Expect = 4e-04 Identities = 37/107 (34%), Positives = 45/107 (42%), Gaps = 11/107 (10%) Query: 25 PTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP--PPRARRTEPAVPP 82 P RR PP R AP+A+ + + P PP A ++ +P PRA PP Sbjct: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP 160 Query: 83 SCGSGPGAAGALRMGLGRTQRAARVAV-SRALAGTVAAAAGLGARRA 128 S GP G R QRAA +A A A A A G RRA Sbjct: 161 S--PGPAQPGP------RAQRAAPLAAPPPAPAAPPAVAPPAGPRRA 199 Score = 26.9 bits (58), Expect = 9.4 Identities = 13/35 (37%), Positives = 16/35 (45%), Gaps = 1/35 (2%) Query: 2 AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPP 36 A + +PSP+ P PP P P GCPP Sbjct: 417 ASVATGPDSPSPV-PLPPGKPALPGADGTPFGCPP 450 >gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens] Length = 1516 Score = 53.9 bits (128), Expect = 7e-08 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 1/91 (1%) Query: 1 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60 +A +A + P+P P P R A G P +RP+P S SP R+ GPF P + Sbjct: 734 LAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPST 793 Query: 61 HASTS-SRSPPPRARRTEPAVPPSCGSGPGA 90 +S S S SPPP ++PP S P A Sbjct: 794 DSSASTSCSPPPEQPTATESLPPWSHSCPSA 824 >gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens] Length = 1516 Score = 53.9 bits (128), Expect = 7e-08 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 1/91 (1%) Query: 1 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60 +A +A + P+P P P R A G P +RP+P S SP R+ GPF P + Sbjct: 734 LAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPST 793 Query: 61 HASTS-SRSPPPRARRTEPAVPPSCGSGPGA 90 +S S S SPPP ++PP S P A Sbjct: 794 DSSASTSCSPPPEQPTATESLPPWSHSCPSA 824 >gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo sapiens] Length = 402 Score = 52.4 bits (124), Expect = 2e-07 Identities = 44/133 (33%), Positives = 52/133 (39%), Gaps = 18/133 (13%) Query: 3 GASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHA 62 GA + A P P PPPP P P AP + P P P++ +P RAAGP P Sbjct: 14 GAESGDAEPPPQPPPPPPPTPPPGEPAP-VPAAPRYLPPLPASPETPERAAGPSEPLGEV 72 Query: 63 STSSRSPPPRARRTEPAVPP-----SCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTV 117 + PR R + PP G AAG G R AA A G Sbjct: 73 A-------PRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAA-----AAKGGPG 120 Query: 118 AAAAGLGARRARR 130 + AG G R RR Sbjct: 121 ESEAGAGGERERR 133 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 51.6 bits (122), Expect = 4e-07 Identities = 39/100 (39%), Positives = 44/100 (44%), Gaps = 12/100 (12%) Query: 8 RAAPSPILPP---PPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSR---AAGPFLPPSH 61 R AP P P PP PP P P PP PAR + P PSR AA P PPS Sbjct: 274 RQAPPPPPPSRGGPPPPPPPPHNSGP----PPPPARGRGAPPPPPSRAPTAAPPPPPPSR 329 Query: 62 ASTSSRSPPPRAR--RTEPAVPPSCGSGPGAAGALRMGLG 99 S + PPP PA+P S SGP +G+G Sbjct: 330 PSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVG 369 Score = 45.1 bits (105), Expect = 3e-05 Identities = 28/75 (37%), Positives = 32/75 (42%), Gaps = 8/75 (10%) Query: 16 PPPP----DLPPTPTRRAPLIGCPPSP-ARPAPSASPSPSRAAGPFLP---PSHASTSSR 67 PPPP PP P RAP PP P +RP+ + P P P P PS A + Sbjct: 300 PPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPP 359 Query: 68 SPPPRARRTEPAVPP 82 PPP P PP Sbjct: 360 PPPPSVLGVGPVAPP 374 Score = 42.0 bits (97), Expect = 3e-04 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 7/83 (8%) Query: 3 GASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPAR---PAPSASPSPSRAAGPFLPP 59 GA + +P PPP P P+ P PP P R P P A PS + + P PP Sbjct: 308 GAPPPPPSRAPTAAPPPPPPSRPSVAVP----PPPPNRMYPPPPPALPSSAPSGPPPPPP 363 Query: 60 SHASTSSRSPPPRARRTEPAVPP 82 S +PPP P PP Sbjct: 364 SVLGVGPVAPPPPPPPPPPPGPP 386 Score = 30.8 bits (68), Expect = 0.65 Identities = 16/43 (37%), Positives = 20/43 (46%), Gaps = 2/43 (4%) Query: 7 ARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSP 49 A + +P PPPP PP+ P+ PP P P P P P Sbjct: 349 ALPSSAPSGPPPP--PPSVLGVGPVAPPPPPPPPPPPGPPPPP 389 Score = 30.8 bits (68), Expect = 0.65 Identities = 15/40 (37%), Positives = 18/40 (45%), Gaps = 6/40 (15%) Query: 13 PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRA 52 P+ PPPP PP P G PP P P+ P+ A Sbjct: 370 PVAPPPPPPPPPPP------GPPPPPGLPSDGDHQVPTTA 403 Score = 28.5 bits (62), Expect = 3.2 Identities = 25/96 (26%), Positives = 34/96 (35%), Gaps = 4/96 (4%) Query: 5 SAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS- 63 S+A + P P PPP L P P PP P P P PS P + A+ Sbjct: 352 SSAPSGPPP--PPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAAL 409 Query: 64 -TSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGL 98 R + + + P SC +R G+ Sbjct: 410 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGI 445 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 51.2 bits (121), Expect = 5e-07 Identities = 48/157 (30%), Positives = 67/157 (42%), Gaps = 30/157 (19%) Query: 1 MAGASAARAAPSP-----ILPPPPDL--PPTPTRRAPLIGCPPSPARPAPSASPSPSRAA 53 + G + R+ P P I PPPP PP P R P PP+ R P P P A Sbjct: 331 IVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPG-AG 389 Query: 54 GPFL-------PPSHASTSSRSPPPRARRTEPAVPPSCGSGPGAA-GAL----RMGL--- 98 GP + PP +S + +PPP PA+ P+ G PG GAL R G+ Sbjct: 390 GPPMPPPPPPPPPPPSSGNGPAPPP----LPPALVPAGGLAPGGGRGALLDQIRQGIQLN 445 Query: 99 ---GRTQRAARVAVSRALAGTVAAAAGLGARRARRLH 132 G + +A ++ G V A + +R+R +H Sbjct: 446 KTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIH 482 Score = 39.7 bits (91), Expect = 0.001 Identities = 36/116 (31%), Positives = 41/116 (35%), Gaps = 31/116 (26%) Query: 16 PPPPDLPPTPTRRAPLIG--------CPPSP---ARPAPS--ASPSPSRAAGPFLPPSHA 62 PPPP R P++G PP P A P P+ P P R P PP Sbjct: 316 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPAT 375 Query: 63 STSSRSPPPRARRTEPAV---------PPSCGSGPG---------AAGALRMGLGR 100 S PPP P + PPS G+GP AG L G GR Sbjct: 376 GRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGR 431 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 50.4 bits (119), Expect = 8e-07 Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 7/93 (7%) Query: 7 ARAAPSPILPPPPDLPPTPTRRAPLIGCP-----PSPARPAPSASPSPSRAAGPFLPPSH 61 A P P+ P PP P P + G P PSPA P+P+ P + A P PPS Sbjct: 1263 AHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPA-PSPARQPPAALAKPPGTPPSL 1321 Query: 62 ASTSSRSPPPRARRTE-PAVPPSCGSGPGAAGA 93 ++ ++ P P A PA PP + AA A Sbjct: 1322 GASPAKPPSPGAPALHVPAKPPRAAAAAAAAAA 1354 Score = 43.5 bits (101), Expect = 1e-04 Identities = 42/130 (32%), Positives = 54/130 (41%), Gaps = 26/130 (20%) Query: 10 APSPILPPP-PDLP--PTPT-RRAPLIGC-------------PPSPARPAPSASPSPSRA 52 +P P+L P P L PTPT ++ PL G P SP P P +P P +A Sbjct: 1227 SPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKA 1286 Query: 53 AGPFLPPSHASTSSRSP---PPRARRTEPAVPPSCGSGPG-----AAGALRMGLGRTQRA 104 S + + SP PP A P PPS G+ P A AL + + RA Sbjct: 1287 VAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVP-AKPPRA 1345 Query: 105 ARVAVSRALA 114 A A + A A Sbjct: 1346 AAAAAAAAAA 1355 Score = 40.0 bits (92), Expect = 0.001 Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 15/100 (15%) Query: 5 SAARAAPSPILPPPPDLPPTPTRRAPLIGCPP------SPARPAPSASPSPSRAAGPFLP 58 ++ +A P + PPPP P PT A L PP PA+P S P ++ P L Sbjct: 1182 ASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPV-PKLQ 1240 Query: 59 PSHASTSSRSPPP--------RARRTEPAVPPSCGSGPGA 90 S TS + P P RA T P V P P A Sbjct: 1241 GSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTA 1280 Score = 38.1 bits (87), Expect = 0.004 Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 11/90 (12%) Query: 1 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPS-PARPAPSASPSPSRAAGPFLPP 59 +AG + A PSP P P PP + P G PPS A PA SP P PP Sbjct: 1287 VAGLPSGSAGPSPA-PSPARQPPAALAKPP--GTPPSLGASPAKPPSPGAPALHVPAKPP 1343 Query: 60 SHASTSSRSPPPRARRTEPAVPPSCGSGPG 89 A+ ++ A P PP G+ PG Sbjct: 1344 RAAAAAA------AAAAAPPAPPE-GASPG 1366 Score = 34.3 bits (77), Expect = 0.059 Identities = 34/125 (27%), Positives = 47/125 (37%), Gaps = 27/125 (21%) Query: 5 SAARAAPSP-ILPP------PPDLPPTPTRRAPLIGCPP------SPARPAPSASPSPSR 51 + A+ P+P +LPP P LP +PT R P PA P P+ P P+ Sbjct: 800 ATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTA 859 Query: 52 AAGPFLPP------------SHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLG 99 LPP +H+ + R E VP +GP A R+G Sbjct: 860 VPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVP--AAAGPYATVQRRVGRS 917 Query: 100 RTQRA 104 + RA Sbjct: 918 HSVRA 922 Score = 28.9 bits (63), Expect = 2.5 Identities = 23/83 (27%), Positives = 28/83 (33%), Gaps = 15/83 (18%) Query: 11 PSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPP 70 P+P PP P PP P +P LPP TS +PP Sbjct: 733 PAPGTPPREARPGRHGHSIKRASVPPVPGKPR------------QVLPP---GTSHFTPP 777 Query: 71 PRARRTEPAVPPSCGSGPGAAGA 93 +T P P + G G A A Sbjct: 778 QTPTKTRPGSPQALGGPHGPAPA 800 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 50.1 bits (118), Expect = 1e-06 Identities = 43/145 (29%), Positives = 55/145 (37%), Gaps = 29/145 (20%) Query: 16 PPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPPRARR 75 PPPP LPP P + + + PP P P P PS GP PP PPP + Sbjct: 314 PPPPPLPPGPAQAS--VALPPPPGPPPPPPLPS----TGPPPPP--------PPPPLPNQ 359 Query: 76 TEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAAGLGARRARRLHLR- 134 P PP A+G + +R L G AA AG R+ R+ Sbjct: 360 VPPPPPPPPAPPLPASGFFLASMSED--------NRPLTGLAAAIAGAKLRKVSRMEDTS 411 Query: 135 -----GQIGVRRVAGTPEARGRGDG 154 IGV + + GRG+G Sbjct: 412 FPSGGNAIGVNSASSKTDT-GRGNG 435 Score = 31.6 bits (70), Expect = 0.38 Identities = 15/32 (46%), Positives = 17/32 (53%) Query: 11 PSPILPPPPDLPPTPTRRAPLIGCPPSPARPA 42 PS PPPP PP P + P PP+P PA Sbjct: 343 PSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPA 374 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 50.1 bits (118), Expect = 1e-06 Identities = 43/145 (29%), Positives = 55/145 (37%), Gaps = 29/145 (20%) Query: 16 PPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPPRARR 75 PPPP LPP P + + + PP P P P PS GP PP PPP + Sbjct: 314 PPPPPLPPGPAQAS--VALPPPPGPPPPPPLPS----TGPPPPP--------PPPPLPNQ 359 Query: 76 TEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAAGLGARRARRLHLR- 134 P PP A+G + +R L G AA AG R+ R+ Sbjct: 360 VPPPPPPPPAPPLPASGFFLASMSED--------NRPLTGLAAAIAGAKLRKVSRMEDTS 411 Query: 135 -----GQIGVRRVAGTPEARGRGDG 154 IGV + + GRG+G Sbjct: 412 FPSGGNAIGVNSASSKTDT-GRGNG 435 Score = 31.6 bits (70), Expect = 0.38 Identities = 15/32 (46%), Positives = 17/32 (53%) Query: 11 PSPILPPPPDLPPTPTRRAPLIGCPPSPARPA 42 PS PPPP PP P + P PP+P PA Sbjct: 343 PSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPA 374 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 50.1 bits (118), Expect = 1e-06 Identities = 38/106 (35%), Positives = 44/106 (41%), Gaps = 12/106 (11%) Query: 3 GASAARAAPSPILPPPPDLPPT-PTRRAPLIGCP-PSPARPAPSASPSPSRAAGPFLPPS 60 GA+ P P LP P + PP+ P + PL G P P PA P P P P P PP Sbjct: 539 GAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPP-----PPPPPP 593 Query: 61 HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAAR 106 T PPP P PP G P A G LG +A + Sbjct: 594 PPGTDGPVPPP-----PPPPPPPPGGPPDALGRRDSELGPGVKAKK 634 Score = 37.4 bits (85), Expect = 0.007 Identities = 32/91 (35%), Positives = 36/91 (39%), Gaps = 18/91 (19%) Query: 10 APSPILP---PPPDLPP--------TPTRRAPLIGCPPSPARPAPSASP-SPSRAAGPFL 57 AP+P +P P PDL P P PL G PSP PSA P +P P Sbjct: 516 APTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGL-PSPQEAPPSAPPQAPPLPGSPEP 574 Query: 58 PPSHASTSSRSPPPRARRTEPAVPPSCGSGP 88 PP+ PPP P PP GP Sbjct: 575 PPAPPLPGDLPPPP-----PPPPPPPGTDGP 600 Score = 31.2 bits (69), Expect = 0.50 Identities = 20/68 (29%), Positives = 22/68 (32%), Gaps = 6/68 (8%) Query: 11 PSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPP 70 P P P P DLPP P PP P P P P P PP Sbjct: 574 PPPAPPLPGDLPPPPPPP------PPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELG 627 Query: 71 PRARRTEP 78 P + +P Sbjct: 628 PGVKAKKP 635 Score = 29.6 bits (65), Expect = 1.4 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 9/62 (14%) Query: 30 PLIGCPPSPARP--------APSASPSPSRAAGPFLPPSHASTSSRSPPPRARRTEPAVP 81 P G P+P P AP+A P+P AA P PP S + PP A P +P Sbjct: 511 PSGGDAPTPGVPTGSPSPDLAPAAEPAPG-AAPPPPPPLPGLPSPQEAPPSAPPQAPPLP 569 Query: 82 PS 83 S Sbjct: 570 GS 571 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 49.3 bits (116), Expect = 2e-06 Identities = 32/79 (40%), Positives = 38/79 (48%), Gaps = 7/79 (8%) Query: 7 ARAAPSP---ILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS 63 AR P P P P LPP+P PL PPSP+ P PS PS P PPS A Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP-PSLQTLPS---PPATPPSQAP 369 Query: 64 TSSRSPPPRARRTEPAVPP 82 S +PP +A + +PP Sbjct: 370 PSMTTPPMQAPPSLQTIPP 388 Score = 42.4 bits (98), Expect = 2e-04 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 10/85 (11%) Query: 8 RAAPSPILPPPPDLPPTPTRRAPL----------IGCPPSPARPAPSASPSPSRAAGPFL 57 +A PSP PP TP+ +AP PPSP AP + P+ + Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690 Query: 58 PPSHASTSSRSPPPRARRTEPAVPP 82 PPS A S +PP + + PA PP Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPP 715 Score = 40.8 bits (94), Expect = 6e-04 Identities = 58/198 (29%), Positives = 77/198 (38%), Gaps = 30/198 (15%) Query: 2 AGASA---ARAAPSPILPPPP--DLPPTPTRRAPL--------IGCPPSPARPAPSASPS 48 AGA+A A AP + P PP PP P A L +G P R + Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69 Query: 49 PSRAAGPFLPPSHASTSSRSP---PPRARRTEPAVPPSCGSGPG-------AAGALRMG- 97 +A P A TSSR+P PP + R E A PP+ + PG A+G R G Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERA-PPAKNTSPGPVSSPGRASGTTRPGP 128 Query: 98 LGRTQRAARVAVSRALA---GTVAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDG 154 LG Q+ R++ +A T A + ARR G A +R G Sbjct: 129 LG--QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186 Query: 155 CSLGRVSPDRTPGKGSKG 172 L R +P P ++G Sbjct: 187 VGLPRPAPSARPRPPTEG 204 Score = 40.8 bits (94), Expect = 6e-04 Identities = 29/91 (31%), Positives = 37/91 (40%), Gaps = 13/91 (14%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCPPSP-ARP--APSASPSPSR--------AAGPFLPPS 60 SP+ PPP PP P + PPSP A P +P A+PSP PF PP Sbjct: 612 SPLATPPPQAPPXLA--LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669 Query: 61 HASTSSRSPPPRARRTEPAVPPSCGSGPGAA 91 + PP + P+ P + P A Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700 Score = 40.0 bits (92), Expect = 0.001 Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 4/77 (5%) Query: 10 APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASP---SPSRAAGPF-LPPSHASTS 65 AP P+ PP L P I PP A PA ++ P PS P PP A Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624 Query: 66 SRSPPPRARRTEPAVPP 82 PP +A + PA PP Sbjct: 625 LALPPLQAPPSPPASPP 641 Score = 40.0 bits (92), Expect = 0.001 Identities = 34/94 (36%), Positives = 44/94 (46%), Gaps = 12/94 (12%) Query: 4 ASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPF-LPPSHA 62 A A +P PPP PP +P P SP+ PS +P PS AA P +PPS Sbjct: 655 ALAVHLLQAPFSPPPS--PPVQAPFSPPASPPVSPSATPPSQAP-PSLAAPPLQVPPSPP 711 Query: 63 STS----SRSPPPRARRTEPA----VPPSCGSGP 88 ++ S +PPP+A A VPPS + P Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745 Score = 40.0 bits (92), Expect = 0.001 Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 10/86 (11%) Query: 4 ASAARAAPSPILPPPPDLPPTPTRRAPLI-GCPPSPARPAPSASPSPSRAAGPFLPPSHA 62 A+ AP + PP +PP+P P+ P P P P A+P P P S Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP--PASPP 746 Query: 63 STSSRSPPPRARRTEPAVPPSCGSGP 88 + S +PPPR VPP + P Sbjct: 747 MSPSATPPPR-------VPPLLAAPP 765 Score = 39.7 bits (91), Expect = 0.001 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 7/75 (9%) Query: 12 SPILPPP-PDLPPT---PTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSR 67 +P PP P + P+ P++ P + PP P+P ASP S +A PP A Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA---TPPPQAPPPLA 731 Query: 68 SPPPRARRTEPAVPP 82 +PP + + PA PP Sbjct: 732 APPLQVPPSPPASPP 746 Score = 39.7 bits (91), Expect = 0.001 Identities = 32/88 (36%), Positives = 37/88 (42%), Gaps = 17/88 (19%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPP 71 SP+ PPP PP APL+ PPSP ASP+ P PP+ +S S P Sbjct: 822 SPLATPPPQAPPVLA--APLLQVPPSP-----PASPT---LQAPRRPPTPGPDTSVSGPR 871 Query: 72 RARRTEPAVPP-------SCGSGPGAAG 92 P PP S SGP AG Sbjct: 872 LTLALAPGPPPPPSRSPSSTLSGPDLAG 899 Score = 38.9 bits (89), Expect = 0.002 Identities = 38/121 (31%), Positives = 47/121 (38%), Gaps = 12/121 (9%) Query: 2 AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH 61 AGA + P+P P P RR+ G RPAPSA P P GP S Sbjct: 158 AGARRDTSGPTPGTPSP-----AMARRSRAAGTEVGLPRPAPSARPRPP-TEGPRKSVSS 211 Query: 62 AST-SSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA 120 AS S+ P P ARR PS G G + + T ++ + GT A Sbjct: 212 ASEHSTTEPSPAARRR-----PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266 Query: 121 A 121 A Sbjct: 267 A 267 Score = 38.5 bits (88), Expect = 0.003 Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 14/96 (14%) Query: 3 GASAARAAPSPILPP------PPDLPPTPTRRAPLIGCPPSPARPAPSASPSPS-RAAGP 55 G A A PS P PP + P AP +G P +P A+PSPS A P Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG----PLSSSPLATPSPSGTKARP 316 Query: 56 FLPPSHAST---SSRSPPPRARRTEPAVPPSCGSGP 88 PP +A+T ++ P P P PPS + P Sbjct: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352 Score = 38.5 bits (88), Expect = 0.003 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 5/81 (6%) Query: 9 AAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPF-LPPSHASTSSR 67 A P P PPP PP +P P SP+ P P P AA P +PPS ++ Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP-PLLAAPPLQVPPSPPASLPM 778 Query: 68 SPPPRARRTEPAVPPSCGSGP 88 SP + P PP+ + P Sbjct: 779 SP---LAKPPPQAPPALATPP 796 Score = 37.7 bits (86), Expect = 0.005 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 10/73 (13%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSR-----AAGPFLPPSHASTSS 66 +P+L PP P +PT +A P P P P S S R A GP PPS + +S+ Sbjct: 837 APLLQVPPSPPASPTLQA-----PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891 Query: 67 RSPPPRARRTEPA 79 S P A + A Sbjct: 892 LSGPDLAGHSSSA 904 Score = 37.4 bits (85), Expect = 0.007 Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 19/94 (20%) Query: 9 AAPSPILPPPPDLPP--------------TPTRRAPLIGCPPSPARPAPSASP--SPSRA 52 A P P PP PP P + P + PP A P+P ASP SP Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647 Query: 53 AGPFLPPS---HASTSSRSPPPRARRTEPAVPPS 83 P P + H + SPPP P PP+ Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681 Score = 37.0 bits (84), Expect = 0.009 Identities = 25/84 (29%), Positives = 30/84 (35%), Gaps = 5/84 (5%) Query: 10 APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASP----SPSRAAGPF-LPPSHAST 64 AP + PP L P P + PP AP +P P A P PPS +T Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT 578 Query: 65 SSRSPPPRARRTEPAVPPSCGSGP 88 P P PP+ S P Sbjct: 579 PPPETPSSIATPPPQAPPALASPP 602 Score = 36.2 bits (82), Expect = 0.015 Identities = 32/100 (32%), Positives = 42/100 (42%), Gaps = 20/100 (20%) Query: 9 AAPSPILPP-----PPDLPPTPTRRAPLI-------GCPPSPARPAPSASPSPSRA---A 53 A P P +PP P +PP+P P+ PP+ A P A PSP + Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ 810 Query: 54 GPFLPPSHASTSS-RSPPPRARRTEPA----VPPSCGSGP 88 PF P + S +PPP+A A VPPS + P Sbjct: 811 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850 Score = 35.4 bits (80), Expect = 0.026 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%) Query: 9 AAPSPILPPPPDLPPT----PTRRA-PLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS 63 A P P+ PP P PP+ P+ A P PPS P A PS +P S S Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397 Query: 64 TSSRSPPPRARRTEPAVPPSCGS 86 S ++PP + S GS Sbjct: 398 PSLQAPPSPLALSSLQATTSLGS 420 Score = 35.4 bits (80), Expect = 0.026 Identities = 26/81 (32%), Positives = 32/81 (39%), Gaps = 10/81 (12%) Query: 8 RAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSR 67 +A PSP+ PPP+ P + I PP A P A SP P P S +T Sbjct: 570 QAPPSPLTTPPPETPSS-------IATPPPQA---PPALASPPLQGLPSPPLSPLATPPP 619 Query: 68 SPPPRARRTEPAVPPSCGSGP 88 PP PPS + P Sbjct: 620 QAPPXLALPPLQAPPSPPASP 640 Score = 35.4 bits (80), Expect = 0.026 Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 17/102 (16%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCPPSPA--------RPAPSASPSPSRAAGPFLPPSHAS 63 SP+ PPP PP PL P PA P+ S SP P PP A+ Sbjct: 779 SPLAKPPPQAPPA-LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837 Query: 64 TSSRSPP-PRARRT--EPAVPPSCG-----SGPGAAGALRMG 97 + PP P A T P PP+ G SGP AL G Sbjct: 838 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879 Score = 32.7 bits (73), Expect = 0.17 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 9/81 (11%) Query: 5 SAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAST 64 +A+ +P L PP P P + PPSP P +PS P PP+ AS Sbjct: 548 TASAPLTTPHLETPPCPAPCP------LQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601 Query: 65 SSR---SPPPRARRTEPAVPP 82 + SPP T P P Sbjct: 602 PLQGLPSPPLSPLATPPPQAP 622 Score = 31.6 bits (70), Expect = 0.38 Identities = 30/95 (31%), Positives = 37/95 (38%), Gaps = 17/95 (17%) Query: 11 PSPILPPPPDLPPT--PTRRAPLIGCPPS--PARPAP-----------SASPSPSRAAG- 54 P + PP D P P +PL PS ARP P + PSP A Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341 Query: 55 PFLPPSHASTSSRSPPPRARRTEPA-VPPSCGSGP 88 P PPS ++ S P T P+ PPS + P Sbjct: 342 PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376 Score = 31.2 bits (69), Expect = 0.50 Identities = 26/69 (37%), Positives = 28/69 (40%), Gaps = 5/69 (7%) Query: 6 AARAAPSPILPPPPDLPPTPTRRAPLIGCPPSP--ARPAPSA---SPSPSRAAGPFLPPS 60 A R AP LP PP P I P A PAP A PSP + G + Sbjct: 949 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 1008 Query: 61 HASTSSRSP 69 A SSRSP Sbjct: 1009 GAGASSRSP 1017 Score = 30.8 bits (68), Expect = 0.65 Identities = 33/111 (29%), Positives = 39/111 (35%), Gaps = 39/111 (35%) Query: 11 PSPILPPPPDLPP---TPTRRAPL-------IGCPPSPARPAPSASPSP---------SR 51 PSP PP PP TP +AP I P S P+ A PSP + Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417 Query: 52 AAGPFLPPSH--------------------ASTSSRSPPPRARRTEPAVPP 82 P L +H AST SPP +A + PA PP Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468 Score = 29.3 bits (64), Expect = 1.9 Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 16/88 (18%) Query: 11 PSPILPPPPDLPPTPTRRAPL-----IGCPPSPA---------RPAPSASPSPSRAAG-- 54 P + P PP+P + L +G P A R ++ SPSR A Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP 451 Query: 55 PFLPPSHASTSSRSPPPRARRTEPAVPP 82 P PP A S + PP PAV P Sbjct: 452 PDSPPLQAPLSLPASPPLQTSLSPAVSP 479 Score = 29.3 bits (64), Expect = 1.9 Identities = 33/113 (29%), Positives = 42/113 (37%), Gaps = 23/113 (20%) Query: 3 GASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSR----------- 51 G + + P L P PP P+R P A + SA+ +P Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921 Query: 52 -AAGPFLPPS------HASTSSRSP-PPRARRTEPAVPPSC--GSGPGAAGAL 94 AA P PP H + SR P PP A R P P +GPG+A L Sbjct: 922 AAASP--PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972 Score = 28.5 bits (62), Expect = 3.2 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 4/53 (7%) Query: 37 SPARPAPSASPSPSRAAGPFLPPSHASTSSRSP---PPRARRTEPAVPPSCGS 86 SPAR PSA +P A P P + R P PPR + PA+ P S Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-KDAAPALGPLSSS 302 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 49.3 bits (116), Expect = 2e-06 Identities = 34/87 (39%), Positives = 38/87 (43%), Gaps = 10/87 (11%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCPP--SPARPAPSASP-SPSRAAGPFLPPSHAS----- 63 SP+ PPP +LP +P A + PP SP P P SP SP A PP S Sbjct: 552 SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611 Query: 64 --TSSRSPPPRARRTEPAVPPSCGSGP 88 S SPPP A R P S S P Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPP 638 Score = 46.6 bits (109), Expect = 1e-05 Identities = 31/84 (36%), Positives = 34/84 (40%), Gaps = 7/84 (8%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSS----- 66 SP+ PPP P +P +PL SP PA SP A P PP S S Sbjct: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE 560 Query: 67 --RSPPPRARRTEPAVPPSCGSGP 88 SPPP A R P S S P Sbjct: 561 LPTSPPPEASRLSPPPEESPMSPP 584 Score = 42.7 bits (99), Expect = 2e-04 Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 23/98 (23%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCPP--SPARPAPSASP-------------------SPS 50 SP+ PPP + P +P A + PP SP P P SP SP Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP 665 Query: 51 RAAGPFLPPSHASTSSRSPPPRARRTEPAVPPSCGSGP 88 P PP S + SPPP A R P S S P Sbjct: 666 PEESPLSPPPEESPT--SPPPEASRLSPPPEDSPTSPP 701 Score = 41.2 bits (95), Expect = 5e-04 Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 5/76 (6%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCP--PSPARPAPSASP-SPSRAAGPFLP--PSHASTSS 66 S + PPP +LP +P A + P SP P P SP SP + PF P S S Sbjct: 465 SRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE 524 Query: 67 RSPPPRARRTEPAVPP 82 SPP A T + PP Sbjct: 525 ESPPSPALETPLSPPP 540 Score = 40.4 bits (93), Expect = 8e-04 Identities = 32/90 (35%), Positives = 39/90 (43%), Gaps = 9/90 (10%) Query: 6 AARAAP----SPILPPPPDLPPTPTRRAPLIGCPPSPAR--PAPSASP-SPSRAAGPFLP 58 A+R +P SP+ PPP + P +P + P +R P P SP SP P P Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682 Query: 59 PSHASTSSRSPPPRARRTEPAVPPSCGSGP 88 P A S SPPP T P S S P Sbjct: 683 PPEA--SRLSPPPEDSPTSPPPEDSPASPP 710 Score = 40.0 bits (92), Expect = 0.001 Identities = 30/83 (36%), Positives = 34/83 (40%), Gaps = 5/83 (6%) Query: 9 AAPSPILPPPPDLPPTPTRRAPLIGCPPS--PARPAPSASP-SPSRAAGPFLPPSHASTS 65 A +P+ PPP P +P + PP P P P AS SP P PP S Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP--PEES 588 Query: 66 SRSPPPRARRTEPAVPPSCGSGP 88 SPPP A R P S S P Sbjct: 589 PMSPPPEASRLFPPFEESPLSPP 611 Score = 38.9 bits (89), Expect = 0.002 Identities = 28/79 (35%), Positives = 34/79 (43%), Gaps = 11/79 (13%) Query: 12 SPILPPPPDLPPTPT-RRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS------- 63 SP+ PPP + P +P +P SP P + PSP+ P PP AS Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET-PLSPPPEASPLSPPFE 550 Query: 64 TSSRSPPPRARRTEPAVPP 82 S SPPP T P PP Sbjct: 551 ESPLSPPPEELPTSP--PP 567 Score = 37.7 bits (86), Expect = 0.005 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 10/87 (11%) Query: 6 AARAAP----SPILPPPPDLPPTPTRRAPLIGCP--PSPARPAPSASPSPSRAAGPFLPP 59 A+R +P SP PPP D P +P L+ P SP P P R+ GP L P Sbjct: 686 ASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP 745 Query: 60 ----SHASTSSRSPPPRARRTEPAVPP 82 H S P + EP + P Sbjct: 746 RPEEPHLSPRPEEPHLSPQAEEPHLSP 772 Score = 37.7 bits (86), Expect = 0.005 Identities = 31/92 (33%), Positives = 36/92 (39%), Gaps = 16/92 (17%) Query: 9 AAPSPILPPPPDLPPTPTRRAPLIG---------CPPSPARPAPSASPSPSRAAGPFLPP 59 A P P PP PP P++G P P RP+ SPS LPP Sbjct: 4279 AGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPP 4338 Query: 60 SHASTSSRSPPPRARRTEPAVPPSCGSGPGAA 91 +H T P P+ EP PP S P AA Sbjct: 4339 THPGT----PKPQGPTLEP--PPGRVS-PAAA 4363 Score = 37.0 bits (84), Expect = 0.009 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 6 AARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPP--SHAS 63 AA +PI PPP P P+I PPSP P ASP P P H+ Sbjct: 974 AAPILETPISPPPEANCTDPEPVPPMI-LPPSPGSPVGPASPILMEPLPPQCSPLLQHSL 1032 Query: 64 TSSRSPPPRARRTEPAVPPSCGS 86 SPP + + PA+P S S Sbjct: 1033 VPQNSPPSQC--SPPALPLSVPS 1053 Score = 35.8 bits (81), Expect = 0.020 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 6/77 (7%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPP 71 +P+ P + P ++P +G P PA + +PSP F P S+ T + PP Sbjct: 2329 APLTPRASQVEP----QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSY--TDPYAQPP 2382 Query: 72 RARRTEPAVPPSCGSGP 88 R +P P SC + P Sbjct: 2383 LTPRPQPPPPESCCALP 2399 Score = 35.4 bits (80), Expect = 0.026 Identities = 29/86 (33%), Positives = 35/86 (40%), Gaps = 15/86 (17%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCPP--SPARPAPS---ASPSPSRA-------AGPFLP- 58 SP+ PPP + P +P A + PP SP P P ASP P + P LP Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728 Query: 59 PSHASTSSRSPPPR--ARRTEPAVPP 82 P RS P R EP + P Sbjct: 729 PEEPQLCPRSEGPHLSPRPEEPHLSP 754 Score = 35.0 bits (79), Expect = 0.034 Identities = 49/185 (26%), Positives = 64/185 (34%), Gaps = 20/185 (10%) Query: 10 APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLP-PSHASTSSRS 68 A P+ P P PP P P P P++ S S + P P P A S Sbjct: 2379 AQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPS 2438 Query: 69 P-PPRARRTEP-AVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAAGLGAR 126 P PR + +P + PPS L R Q + +LA T A G A Sbjct: 2439 PVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP-PRPQPPEVAFKAGSLAHTSLGAGGFPA- 2496 Query: 127 RARRLHLRGQIGVRRVAGTPE--ARGRGDGCSLGRVSPDR------------TPGKGSKG 172 A G++ + +G P R G G +G SP R P G Sbjct: 2497 -ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG 2555 Query: 173 MEPPH 177 + PPH Sbjct: 2556 LPPPH 2560 Score = 33.5 bits (75), Expect = 0.100 Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 12/75 (16%) Query: 13 PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS-HAS----TSSR 67 P+LPPP + P +P P P SP A SP P LP + H S S Sbjct: 439 PLLPPPEESPLSP----PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL 494 Query: 68 SPPPRARRTEPAVPP 82 SPPP P PP Sbjct: 495 SPPP---EESPLSPP 506 Score = 33.5 bits (75), Expect = 0.100 Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 14/73 (19%) Query: 9 AAPSPILPPPPDLPPTPTRRA----PLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAST 64 +AP P P PP P P+ + PL+ P P P SP P +S Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLA----------SSP 4956 Query: 65 SSRSPPPRARRTE 77 S P PRAR E Sbjct: 4957 ESARPKPRARPPE 4969 Score = 32.7 bits (73), Expect = 0.17 Identities = 33/113 (29%), Positives = 43/113 (38%), Gaps = 31/113 (27%) Query: 13 PILPPPPDLPPTPTRRAPLIG--CPPSPARPAPSASPSPSRAAGPFLPP----------- 59 P+ P P +LP +P+ L PP P P SP + AA P L P Sbjct: 907 PLSPLPEELPLSPSGEPSLSPQLMPPDPL--PPPLSPIITAAAPPALSPLGELEYPFGAK 964 Query: 60 ----------SHASTSSRSPPPRARRTEP------AVPPSCGSGPGAAGALRM 96 + + SPPP A T+P +PPS GS G A + M Sbjct: 965 GDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILM 1017 Score = 29.3 bits (64), Expect = 1.9 Identities = 25/89 (28%), Positives = 33/89 (37%), Gaps = 3/89 (3%) Query: 4 ASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS 63 A + +A + PP +P + + PP PS P A P L P + Sbjct: 2133 AGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYP-LEPRFPT 2191 Query: 64 TSSRSPPPRARRTEPAVPPSCG--SGPGA 90 PP + PA PP G S PGA Sbjct: 2192 APPTYPPYPSPTGAPAQPPMLGASSRPGA 2220 Score = 29.3 bits (64), Expect = 1.9 Identities = 30/118 (25%), Positives = 42/118 (35%), Gaps = 20/118 (16%) Query: 2 AGASAARAAPSPI-LPPPPDLPPTPTRRAPLIGCPPSPARPA-----PSASPSPSRAAGP 55 AG+ +P + L PP +P + P P P P P+ P PS P Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206 Query: 56 FLPPSHASTSS---------RSPPPRARRTEPAVP-----PSCGSGPGAAGALRMGLG 99 PP ++S + PP R +P+ P P C S A G+G Sbjct: 2207 AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG 2264 Score = 28.5 bits (62), Expect = 3.2 Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 12/86 (13%) Query: 32 IGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP-----------PPRARRTEPAV 80 +G P P P +P + + GP L P H + SP P TE + Sbjct: 4277 LGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQL 4336 Query: 81 PPSCGSGPGAAG-ALRMGLGRTQRAA 105 PP+ P G L GR AA Sbjct: 4337 PPTHPGTPKPQGPTLEPPPGRVSPAA 4362 Score = 27.7 bits (60), Expect = 5.5 Identities = 28/105 (26%), Positives = 37/105 (35%), Gaps = 20/105 (19%) Query: 2 AGASAARAAPSPILPPPPDLP----------PTPTRRAPLI-------GCPPSPARP--A 42 A + P ILPP P P P P + +PL+ PPS P Sbjct: 988 ANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL 1047 Query: 43 PSASPSPSRAAGPFLPPSHASTSSRSPPPRARRTE-PAVPPSCGS 86 P + PSP G + S + + E PA+ PS S Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATS 1092 >gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo sapiens] Length = 355 Score = 48.5 bits (114), Expect = 3e-06 Identities = 59/171 (34%), Positives = 66/171 (38%), Gaps = 17/171 (9%) Query: 10 APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP 69 A SP LP P D P AP + P A SRA G + A +SSR P Sbjct: 97 ASSPRLPLPADSEPDAYTSAP------RGSGPTYCAGAGNSRAGGGLTKYNSAHSSSRVP 150 Query: 70 PPRARRTEPAVPPSCGSGPG-AAGALRMGLGRTQRAARVAVSRALAGTVAAAAG---LGA 125 PR SCG GPG + A R GLG R+AR R T G GA Sbjct: 151 RPRLPSQRRGA--SCGLGPGPESRAARQGLG--GRSARARTRRGPHRTRRPEPGPHHTGA 206 Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPP 176 R+A L G G R AGT A RG L S G+ PP Sbjct: 207 RQAG--PLPGTRGRTRAAGTGSA-ARGPARHLRGGSVAAAAAARCLGLSPP 254 Score = 38.9 bits (89), Expect = 0.002 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 22/167 (13%) Query: 21 LPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH---------ASTSSRSPPP 71 L PTP+ + C PSP A S P + + PFLP S +S SR P P Sbjct: 21 LHPTPSEA---LSCWPSPPGEAYSLPELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSP 77 Query: 72 RARRTEPAVPPSCGSGPGAAGALRMGLGRTQR------AARVAVSRALAGTVAAAAGLGA 125 T P P G A + R+ L A R + AG + AG G Sbjct: 78 AHPWTTPQPGPPHQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGL 137 Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKG 172 + H ++ R+ P R RG C LG R +G G Sbjct: 138 TKYNSAHSSSRVPRPRL---PSQR-RGASCGLGPGPESRAARQGLGG 180 >gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo sapiens] Length = 355 Score = 48.5 bits (114), Expect = 3e-06 Identities = 59/171 (34%), Positives = 66/171 (38%), Gaps = 17/171 (9%) Query: 10 APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP 69 A SP LP P D P AP + P A SRA G + A +SSR P Sbjct: 97 ASSPRLPLPADSEPDAYTSAP------RGSGPTYCAGAGNSRAGGGLTKYNSAHSSSRVP 150 Query: 70 PPRARRTEPAVPPSCGSGPG-AAGALRMGLGRTQRAARVAVSRALAGTVAAAAG---LGA 125 PR SCG GPG + A R GLG R+AR R T G GA Sbjct: 151 RPRLPSQRRGA--SCGLGPGPESRAARQGLG--GRSARARTRRGPHRTRRPEPGPHHTGA 206 Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPP 176 R+A L G G R AGT A RG L S G+ PP Sbjct: 207 RQAG--PLPGTRGRTRAAGTGSA-ARGPARHLRGGSVAAAAAARCLGLSPP 254 Score = 38.9 bits (89), Expect = 0.002 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 22/167 (13%) Query: 21 LPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH---------ASTSSRSPPP 71 L PTP+ + C PSP A S P + + PFLP S +S SR P P Sbjct: 21 LHPTPSEA---LSCWPSPPGEAYSLPELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSP 77 Query: 72 RARRTEPAVPPSCGSGPGAAGALRMGLGRTQR------AARVAVSRALAGTVAAAAGLGA 125 T P P G A + R+ L A R + AG + AG G Sbjct: 78 AHPWTTPQPGPPHQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGL 137 Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKG 172 + H ++ R+ P R RG C LG R +G G Sbjct: 138 TKYNSAHSSSRVPRPRL---PSQR-RGASCGLGPGPESRAARQGLGG 180 >gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo sapiens] Length = 355 Score = 48.5 bits (114), Expect = 3e-06 Identities = 59/171 (34%), Positives = 66/171 (38%), Gaps = 17/171 (9%) Query: 10 APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP 69 A SP LP P D P AP + P A SRA G + A +SSR P Sbjct: 97 ASSPRLPLPADSEPDAYTSAP------RGSGPTYCAGAGNSRAGGGLTKYNSAHSSSRVP 150 Query: 70 PPRARRTEPAVPPSCGSGPG-AAGALRMGLGRTQRAARVAVSRALAGTVAAAAG---LGA 125 PR SCG GPG + A R GLG R+AR R T G GA Sbjct: 151 RPRLPSQRRGA--SCGLGPGPESRAARQGLG--GRSARARTRRGPHRTRRPEPGPHHTGA 206 Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPP 176 R+A L G G R AGT A RG L S G+ PP Sbjct: 207 RQAG--PLPGTRGRTRAAGTGSA-ARGPARHLRGGSVAAAAAARCLGLSPP 254 Score = 38.9 bits (89), Expect = 0.002 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 22/167 (13%) Query: 21 LPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH---------ASTSSRSPPP 71 L PTP+ + C PSP A S P + + PFLP S +S SR P P Sbjct: 21 LHPTPSEA---LSCWPSPPGEAYSLPELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSP 77 Query: 72 RARRTEPAVPPSCGSGPGAAGALRMGLGRTQR------AARVAVSRALAGTVAAAAGLGA 125 T P P G A + R+ L A R + AG + AG G Sbjct: 78 AHPWTTPQPGPPHQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGL 137 Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKG 172 + H ++ R+ P R RG C LG R +G G Sbjct: 138 TKYNSAHSSSRVPRPRL---PSQR-RGASCGLGPGPESRAARQGLGG 180 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 47.8 bits (112), Expect = 5e-06 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 6/75 (8%) Query: 13 PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPS-RAAGPFLPPSHASTSSRSPP- 70 P PPPP +PP P P PP+P P P + +P+ P LPP+HA PP Sbjct: 479 PPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHA-VPPHPPPG 537 Query: 71 ---PRARRTEPAVPP 82 P A PAVPP Sbjct: 538 LGLPPASYPPPAVPP 552 Score = 40.4 bits (93), Expect = 8e-04 Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 8/73 (10%) Query: 11 PSPILPPP-PDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP 69 P P +PPP P PP P P PP P R P+ + P G LPP +S P Sbjct: 495 PPPAIPPPTPGYPPPPPTYNP--NFPPPPPRLPPTHAVPPHPPPGLGLPP-----ASYPP 547 Query: 70 PPRARRTEPAVPP 82 P +P VPP Sbjct: 548 PAVPPGGQPPVPP 560 Score = 39.7 bits (91), Expect = 0.001 Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 10/94 (10%) Query: 16 PPPPDLPPTPTRRAPLIGCPPSPARPAP-SASPSPSRAAGPF---------LPPSHASTS 65 PPPP +P T PL P P R P +A+ + GP +PP Sbjct: 350 PPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP 409 Query: 66 SRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLG 99 PPP R P P S +G + G G Sbjct: 410 VHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEG 443 Score = 26.9 bits (58), Expect = 9.4 Identities = 21/92 (22%), Positives = 30/92 (32%), Gaps = 24/92 (26%) Query: 15 LPPPPDLPPTPT-----RRAPLIGCPPS-------------------PARPAPSASPSPS 50 L PP L PTP + P PS P +P+P S Sbjct: 273 LQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQ 332 Query: 51 RAAGPFLPPSHASTSSRSPPPRARRTEPAVPP 82 + P + ++ PPP+ + E PP Sbjct: 333 VKRAVVVSPKEENKAAEPPPPKIPKIETTHPP 364 >gi|156071470 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 [Homo sapiens] Length = 889 Score = 47.0 bits (110), Expect = 9e-06 Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 17/110 (15%) Query: 2 AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSP--------------ARPAPSASP 47 A A+A+ P P PP P R +P G P +P +RP ++ P Sbjct: 766 APAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPLSASQP 825 Query: 48 S-PSRAAGPFLP--PSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGAL 94 S P A GP P+ +ST P P AR P+ + PGAAG L Sbjct: 826 SLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAAGGL 875 Score = 46.2 bits (108), Expect = 1e-05 Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 23/142 (16%) Query: 3 GASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARP--APSASPSPSRAAGPFLPPS 60 G + A A+P P PPP PP G P SP P +P + AGP LP Sbjct: 764 GPAPAAASPGP---PPPASPP---------GAPASPRAPRTSPYGGLPAAPLAGPALPAR 811 Query: 61 HASTSSRSPPPRARRTEPAVP-----PSCGSGPGAAGALRMGLGRTQRAARVAVSRALAG 115 S +SR ++P++P P+ + P ++ R+G RAA + R + Sbjct: 812 RLSRASRP----LSASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSA 867 Query: 116 TVAAAAGLGARRARRLHLRGQI 137 + AA GL + + R L + Sbjct: 868 SPGAAGGLDPQDSARSRLSSNL 889 Score = 43.1 bits (100), Expect = 1e-04 Identities = 34/102 (33%), Positives = 38/102 (37%), Gaps = 20/102 (19%) Query: 7 ARAAPSPILPPPP----DLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLP---- 58 A AP P PPPP PP P AP G P+P + P A P AA P Sbjct: 16 ATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGRL 75 Query: 59 ------------PSHASTSSRSPPPRARRTEPAVPPSCGSGP 88 P AST+ SP R EP P+ GP Sbjct: 76 RSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGP 117 Score = 41.6 bits (96), Expect = 4e-04 Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 3/92 (3%) Query: 9 AAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRS 68 A P+P PPPP PP P ++ P PP+P P P +P LPP A Sbjct: 16 ATPAPGPPPPP--PPAPPQQQPPPPPPPAPP-PGPGPAPPQHPPRAEALPPEAADEGGPR 72 Query: 69 PPPRARRTEPAVPPSCGSGPGAAGALRMGLGR 100 R+R + P + G+ A G+ GR Sbjct: 73 GRLRSRDSSCGRPGTPGAASTAKGSPNGECGR 104 Score = 40.8 bits (94), Expect = 6e-04 Identities = 31/95 (32%), Positives = 35/95 (36%), Gaps = 22/95 (23%) Query: 2 AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPF-LPPS 60 A R SP P P PP P PP+P + P P P+ GP PP Sbjct: 3 ARGGGGRPGESPGATPAPGPPPPP---------PPAPPQQQPPPPPPPAPPPGPGPAPPQ 53 Query: 61 HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALR 95 H PPRA A+PP G G LR Sbjct: 54 H--------PPRAE----ALPPEAADEGGPRGRLR 76 Score = 34.7 bits (78), Expect = 0.045 Identities = 42/166 (25%), Positives = 60/166 (36%), Gaps = 23/166 (13%) Query: 17 PPPDLPPTPT------RRAPLIGCPPSPARP--APSASPSPSRAAGPFLPPSHASTSSRS 68 PPP PP T ++A + P ARP P A SP P P+ A+ S Sbjct: 715 PPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGP 774 Query: 69 PPP----------RARRTEP--AVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGT 116 PPP RA RT P +P + +GP R A++ ++ G Sbjct: 775 PPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPGP 834 Query: 117 VAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSP 162 A+ + R L R A +P+ R + G + P Sbjct: 835 AASTRPASSSTPR---LGPTPAARAAAPSPDRRDSASPGAAGGLDP 877 >gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 47.0 bits (110), Expect = 9e-06 Identities = 53/179 (29%), Positives = 73/179 (40%), Gaps = 17/179 (9%) Query: 4 ASAARAAPSPILPPPPDLPPTPTRR---APL----IGCPPSPARPAPSASPSPSRAAGPF 56 A A+ P P+L P P P P AP+ + P+PA PAP+ +P+P A P Sbjct: 132 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAPVAAPAPA 190 Query: 57 LPPSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGT 116 P+ A + +P P A E A G+ G G + Q + ++ R AGT Sbjct: 191 PAPAPAPAPAPAPAPDAAPQESA---EQGANQGQRGQEPLA---DQLHSGIS-GRPAAGT 243 Query: 117 VAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEP 175 AA+A A + L +R PE + GD SP PG GS P Sbjct: 244 AAASANGAAIKKLSGPLISDFFAKRKRSAPE-KSSGD-VPAPCPSPSAAPGVGSVEQTP 300 >gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 47.0 bits (110), Expect = 9e-06 Identities = 53/179 (29%), Positives = 73/179 (40%), Gaps = 17/179 (9%) Query: 4 ASAARAAPSPILPPPPDLPPTPTRR---APL----IGCPPSPARPAPSASPSPSRAAGPF 56 A A+ P P+L P P P P AP+ + P+PA PAP+ +P+P A P Sbjct: 132 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAPVAAPAPA 190 Query: 57 LPPSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGT 116 P+ A + +P P A E A G+ G G + Q + ++ R AGT Sbjct: 191 PAPAPAPAPAPAPAPDAAPQESA---EQGANQGQRGQEPLA---DQLHSGIS-GRPAAGT 243 Query: 117 VAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEP 175 AA+A A + L +R PE + GD SP PG GS P Sbjct: 244 AAASANGAAIKKLSGPLISDFFAKRKRSAPE-KSSGD-VPAPCPSPSAAPGVGSVEQTP 300 >gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo sapiens] Length = 316 Score = 47.0 bits (110), Expect = 9e-06 Identities = 53/179 (29%), Positives = 73/179 (40%), Gaps = 17/179 (9%) Query: 4 ASAARAAPSPILPPPPDLPPTPTRR---APL----IGCPPSPARPAPSASPSPSRAAGPF 56 A A+ P P+L P P P P AP+ + P+PA PAP+ +P+P A P Sbjct: 143 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAPVAAPAPA 201 Query: 57 LPPSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGT 116 P+ A + +P P A E A G+ G G + Q + ++ R AGT Sbjct: 202 PAPAPAPAPAPAPAPDAAPQESA---EQGANQGQRGQEPLA---DQLHSGIS-GRPAAGT 254 Query: 117 VAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEP 175 AA+A A + L +R PE + GD SP PG GS P Sbjct: 255 AAASANGAAIKKLSGPLISDFFAKRKRSAPE-KSSGD-VPAPCPSPSAAPGVGSVEQTP 311 >gi|56118221 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein [Homo sapiens] Length = 666 Score = 47.0 bits (110), Expect = 9e-06 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 10/81 (12%) Query: 11 PSPILPPPPD-LPPTPTRRAPLIGC---PPSPARPAPSASPSPSRAAGPFLPPSHASTSS 66 P + PPPD +PP P A + G PP P PAP+ +P P A P + + Sbjct: 572 PPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPP------PAVAK 625 Query: 67 RSPPPRARRTEPAVPPSCGSG 87 R P P R+ P P G G Sbjct: 626 RPPVPPKRQENPGHPGGAGGG 646 Score = 41.6 bits (96), Expect = 4e-04 Identities = 35/105 (33%), Positives = 40/105 (38%), Gaps = 20/105 (19%) Query: 3 GASAARAAPSPILPPPP-----DLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFL 57 G A P LPPPP D P P + PP P P PS + AG L Sbjct: 542 GGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPP---PSYAGIAGSEL 598 Query: 58 P----------PSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAG 92 P P+ S+R PP A+R P VPP PG G Sbjct: 599 PPPPPPPPAPAPAPVPDSARPPPAVAKR--PPVPPKRQENPGHPG 641 >gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] Length = 1159 Score = 47.0 bits (110), Expect = 9e-06 Identities = 40/126 (31%), Positives = 48/126 (38%), Gaps = 28/126 (22%) Query: 23 PTPTRRAPLIGCPPSPARP----------------APSASPSPSRAAG-------PFLPP 59 P PT RAP G PP P P A SP P R P PP Sbjct: 13 PGPTARAPSPGAPPPPRSPRSRPLLLLLLLLGACGAAGRSPEPGRLGPHAQLTRVPRSPP 72 Query: 60 SHASTSSRSPPPRARRTEPAVP---PSCGSGPGAAGALRMGLGRTQRAARVA--VSRALA 114 + + +AR TEP P P GPG GA G R +RAA +A SRA Sbjct: 73 AGRAEPGGGEDRQARGTEPGAPGPSPGPAPGPGEDGAPAAGYRRWERAAPLAGVASRAQV 132 Query: 115 GTVAAA 120 ++ + Sbjct: 133 SLISTS 138 >gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo sapiens] Length = 1336 Score = 47.0 bits (110), Expect = 9e-06 Identities = 43/128 (33%), Positives = 51/128 (39%), Gaps = 33/128 (25%) Query: 1 MAGASAARAAPSPILPPPPDL-PPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPP 59 M +A AAP P PPPP PSPA PAP +P P+ PF+P Sbjct: 893 MYSCCSAEAAPPPAKPPPPPQP-------------LPSPAYPAPRPAPGPA----PFVPR 935 Query: 60 SHASTSSRSPPPRARRTEPAVPPSCGS---------GPGAAGALRMGLGRTQRAARVAVS 110 AS R RRT+ A PP GP L +GLG + A R A Sbjct: 936 ERASVD------RWRRTKGAGPPGGAGLADGFHRYYGPIEPQGLGLGLGEARAAPRGAAG 989 Query: 111 RALAGTVA 118 R L+ A Sbjct: 990 RPLSPPAA 997 Score = 40.4 bits (93), Expect = 8e-04 Identities = 37/109 (33%), Positives = 44/109 (40%), Gaps = 23/109 (21%) Query: 3 GASAARAAPS-----PILPP---PPDLPPTP---------TRRAPLIGCPPSPARPAPSA 45 G ARAAP P+ PP PP PP P P P+ PAP A Sbjct: 976 GLGEARAAPRGAAGRPLSPPAAQPPQKPPPSYFAIVRDKEPAEPPAGAFPGFPSPPAPPA 1035 Query: 46 SPSPSRAAGPFLPPSHASTSSRSPPPRAR--RTEPAVPPSCGSGPGAAG 92 + + A GP P + SPP AR R++P P G G G AG Sbjct: 1036 AAAT--AVGP--PLCRLAFEDESPPAPARWPRSDPESQPLLGPGAGGAG 1080 Score = 31.6 bits (70), Expect = 0.38 Identities = 45/137 (32%), Positives = 56/137 (40%), Gaps = 34/137 (24%) Query: 16 PPPPDLPPTPTRRAPLIGCPPS-PARPAPS----ASPSP-----SRAAGPF-LPPSHAST 64 PPP P P RRA GCP S P RP S A+ +P RAAG + LPP Sbjct: 1211 PPPWAAGPLPRRRARC-GCPRSHPHRPRASHRTPAAAAPHHHRHRRAAGGWDLPP----- 1264 Query: 65 SSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAAGLG 124 P P +R E S P AA A R+ G ++ A R + + A Sbjct: 1265 ----PAPTSRSLE-----DLSSCPRAAPARRL-TGPSRHARRCPHAAHWGPPLPTA---- 1310 Query: 125 ARRARRLHLRGQIGVRR 141 + R H G +G RR Sbjct: 1311 ---SHRRHRGGDLGTRR 1324 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 47.0 bits (110), Expect = 9e-06 Identities = 33/83 (39%), Positives = 38/83 (45%), Gaps = 15/83 (18%) Query: 5 SAARAAPSPI-----LPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPP 59 +AA AAPS + LPPPP PP P P PP P P P P P P PP Sbjct: 666 AAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPP---PPQPGFPMPPPLPPPP----PPPPP 718 Query: 60 SHASTSSRSPPPRARRTEPAVPP 82 +H + + PP A P VPP Sbjct: 719 AHPAVTVPPPPLPA---PPGVPP 738 Score = 36.6 bits (83), Expect = 0.012 Identities = 20/47 (42%), Positives = 22/47 (46%), Gaps = 6/47 (12%) Query: 13 PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPP 59 P+ PP P PP P P + PP P PAP P P P LPP Sbjct: 704 PMPPPLPPPPPPPPPAHPAVTVPPPPL-PAPPGVPPP-----PILPP 744 Score = 33.9 bits (76), Expect = 0.077 Identities = 26/74 (35%), Positives = 29/74 (39%), Gaps = 18/74 (24%) Query: 13 PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPPR 72 P++ P P PP P PP P RP PS P P + AS S P P Sbjct: 1271 PMMLPLPLQPPLP---------PPRPPRP-PSPPPEPE--------TTDASHPSVPPEPL 1312 Query: 73 ARRTEPAVPPSCGS 86 A P P CGS Sbjct: 1313 AEDHPPHTPGLCGS 1326 Score = 32.7 bits (73), Expect = 0.17 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 8/81 (9%) Query: 1 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60 ++G S+ + SP +P P P P+ G P +P R S +P+ S +GP L P Sbjct: 1346 LSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDF-SFTPTFSEPSGPLLLPV 1404 Query: 61 HASTSSRSPPPRARRTEPAVP 81 P P RR E + P Sbjct: 1405 -------CPLPTGRRDERSGP 1418 Score = 32.3 bits (72), Expect = 0.22 Identities = 24/82 (29%), Positives = 30/82 (36%), Gaps = 6/82 (7%) Query: 11 PSP-ILPPPPDLPPTPTRRAPLIGCPPSPARP--APSASPSPSRAAGPFLPPSHASTSSR 67 P P ++ P P+ AP + PP P P P P P + P PP Sbjct: 657 PKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPP---LPPPP 713 Query: 68 SPPPRARRTEPAVPPSCGSGPG 89 PPP A PP + PG Sbjct: 714 PPPPPAHPAVTVPPPPLPAPPG 735 Score = 31.6 bits (70), Expect = 0.38 Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 13/96 (13%) Query: 16 PPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPP---- 71 P PP + P P + P + P P P+P P + A+ P +PP + P Sbjct: 1268 PEPPMMLPLPLQ--PPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCG 1325 Query: 72 -----RARRTEPAVPPSCGSGPGAAGALRMGLGRTQ 102 ++ T PA P G P + G+ + L Q Sbjct: 1326 SLAKSQSTETVPATPG--GEPPLSGGSSGLSLSSPQ 1359 Score = 30.8 bits (68), Expect = 0.65 Identities = 28/91 (30%), Positives = 31/91 (34%), Gaps = 7/91 (7%) Query: 11 PSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPP 70 P P+ P P P R P P PAP AS P P P RSPP Sbjct: 1432 PLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRP-------RRSPP 1484 Query: 71 PRARRTEPAVPPSCGSGPGAAGALRMGLGRT 101 P V P G+ G L G +T Sbjct: 1485 SMLSLDGPLVRPPAGAALGRELLLLPGQPQT 1515 Score = 29.3 bits (64), Expect = 1.9 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 15/88 (17%) Query: 5 SAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGP--------- 55 +A AP P LPP P PP P P + P + + PS + GP Sbjct: 1533 NAGIPAPPPPLPPQPPPPPPP----PPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEE 1588 Query: 56 FLPPSHASTSSRSPPPRARRTEPAVPPS 83 ++ + + R PP +R E VPP+ Sbjct: 1589 YMELAKSRGPWRRPP--KKRHEDLVPPA 1614 Score = 28.5 bits (62), Expect = 3.2 Identities = 20/56 (35%), Positives = 22/56 (39%), Gaps = 3/56 (5%) Query: 12 SPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSR 67 +P PPPPD P G P P +P S AGP P H S SR Sbjct: 450 TPPGPPPPDTNSMELGGRPTFGWSPEPC-DSPGTPTLESSPAGPEKP--HDSLDSR 502 Score = 27.3 bits (59), Expect = 7.2 Identities = 18/64 (28%), Positives = 21/64 (32%), Gaps = 9/64 (14%) Query: 16 PPPPDLPPTPTRRAPLIGCPPSPARP---------APSASPSPSRAAGPFLPPSHASTSS 66 P PP LPP G PP P P P+ SP P P +S + Sbjct: 432 PAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAG 491 Query: 67 RSPP 70 P Sbjct: 492 PEKP 495 Score = 27.3 bits (59), Expect = 7.2 Identities = 15/33 (45%), Positives = 16/33 (48%), Gaps = 1/33 (3%) Query: 4 ASAARAAPSPILPPPPDLPPTPTRRAPLIGCPP 36 A A P P LP PP +PP P PL PP Sbjct: 719 AHPAVTVPPPPLPAPPGVPPPPI-LPPLPPFPP 750 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 46.6 bits (109), Expect = 1e-05 Identities = 33/96 (34%), Positives = 34/96 (35%), Gaps = 9/96 (9%) Query: 11 PSPILPPPPDLP-------PTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS 63 P +PPPP LP P P G P P P P P PS A P PP Sbjct: 648 PPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPP--PPPPPP 705 Query: 64 TSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLG 99 SP P P PP G P L GLG Sbjct: 706 PLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLG 741 Score = 44.7 bits (104), Expect = 4e-05 Identities = 30/87 (34%), Positives = 34/87 (39%), Gaps = 14/87 (16%) Query: 13 PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPPR 72 P LPPPP PP P G PP P P SP+P GP PP+ PPP Sbjct: 678 PPLPPPPP-PPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGP--PPAPPPPGLAPPPPP 734 Query: 73 AR-----------RTEPAVPPSCGSGP 88 +PA+ PSC P Sbjct: 735 GLFFGLGSSSSQCPRKPAIEPSCPMKP 761 >gi|210031233 PR domain containing 6 [Homo sapiens] Length = 595 Score = 46.6 bits (109), Expect = 1e-05 Identities = 47/161 (29%), Positives = 61/161 (37%), Gaps = 34/161 (21%) Query: 2 AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH 61 +GA+ +AP P+ PPPP PP P R P PP RP P Sbjct: 38 SGAAGLLSAPQPLQPPPP--PPPPERAEP----PPDSLRPRP------------------ 73 Query: 62 ASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAA 121 AS SS S P + T + SC + AA A GL +++ V LA AA Sbjct: 74 ASLSSASSTPASSSTSASSASSCAA--AAAAAALAGLSALP-VSQLPVFAPLAAAAVAAE 130 Query: 122 GLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSP 162 L + +G G + G G G GR +P Sbjct: 131 PLPPKEL-------CLGATSGPGPVKCGGGGGGGGEGRGAP 164 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.132 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,709,082 Number of Sequences: 37866 Number of extensions: 781949 Number of successful extensions: 22602 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1046 Number of HSP's successfully gapped in prelim test: 1804 Number of HSP's that attempted gapping in prelim test: 7409 Number of HSP's gapped (non-prelim): 10499 length of query: 179 length of database: 18,247,518 effective HSP length: 96 effective length of query: 83 effective length of database: 14,612,382 effective search space: 1212827706 effective search space used: 1212827706 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.