Guide to the Human Genome
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Search of human proteins with 239741571

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo
sapiens]
         (179 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169164209 PREDICTED: hypothetical protein [Homo sapiens]           365   e-101
gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo ...   365   e-101
gi|169163999 PREDICTED: hypothetical protein [Homo sapiens]           169   1e-42
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    56   2e-08
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     56   2e-08
gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]            54   7e-08
gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]             54   7e-08
gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo sa...    52   2e-07
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    52   4e-07
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             51   5e-07
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  50   8e-07
gi|56549694 enabled homolog isoform a [Homo sapiens]                   50   1e-06
gi|39930375 enabled homolog isoform b [Homo sapiens]                   50   1e-06
gi|33356148 formin-like 1 [Homo sapiens]                               50   1e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   2e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    49   2e-06
gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo ...    49   3e-06
gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo ...    49   3e-06
gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo ...    49   3e-06
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         48   5e-06
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    47   9e-06
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    47   9e-06
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    47   9e-06
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    47   9e-06
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    47   9e-06
gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]      47   9e-06
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    47   9e-06
gi|210032580 SET domain containing 1B [Homo sapiens]                   47   9e-06
gi|157168329 formin 1 [Homo sapiens]                                   47   1e-05
gi|210031233 PR domain containing 6 [Homo sapiens]                     47   1e-05

>gi|169164209 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 179

 Score =  365 bits (937), Expect = e-101
 Identities = 179/179 (100%), Positives = 179/179 (100%)

Query: 1   MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60
           MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS
Sbjct: 1   MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60

Query: 61  HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA 120
           HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA
Sbjct: 61  HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA 120

Query: 121 AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG 179
           AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG
Sbjct: 121 AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG 179


>gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo
           sapiens]
          Length = 179

 Score =  365 bits (937), Expect = e-101
 Identities = 179/179 (100%), Positives = 179/179 (100%)

Query: 1   MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60
           MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS
Sbjct: 1   MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60

Query: 61  HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA 120
           HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA
Sbjct: 61  HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA 120

Query: 121 AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG 179
           AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG
Sbjct: 121 AGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPPHTG 179


>gi|169163999 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 84

 Score =  169 bits (428), Expect = 1e-42
 Identities = 84/84 (100%), Positives = 84/84 (100%)

Query: 96  MGLGRTQRAARVAVSRALAGTVAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGC 155
           MGLGRTQRAARVAVSRALAGTVAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGC
Sbjct: 1   MGLGRTQRAARVAVSRALAGTVAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGC 60

Query: 156 SLGRVSPDRTPGKGSKGMEPPHTG 179
           SLGRVSPDRTPGKGSKGMEPPHTG
Sbjct: 61  SLGRVSPDRTPGKGSKGMEPPHTG 84


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 11/98 (11%)

Query: 5   SAARAAPSPILP-PPPDLPPTPTRRAPLIGC--PPSPARPAPSASPSPSR-AAGPFLPPS 60
           S     P+ +LP P P  P T  +  P +G   PP+PA P+P A+P+P+  AA P  PP 
Sbjct: 216 SLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP 275

Query: 61  HASTSSRSP-----PPRARRTEPAVPPSCGSGPGAAGA 93
             +T +R P     PP A    P  PP+     G+AGA
Sbjct: 276 APATLARPPGHPAGPPTAAPAVP--PPAAAQNGGSAGA 311



 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 42/118 (35%), Positives = 50/118 (42%), Gaps = 11/118 (9%)

Query: 11  PSPILP--PPPDLPPTPTRRAPLIG----CPPSPARPAPSASPSPSRAAGPFLPPSHAST 64
           PSP  P  P    PP    R P  G    C P PA  A +A P P+  AGP  P   A+ 
Sbjct: 108 PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA-PAGPAKPAGPAAL 166

Query: 65  SSRSPPPRARRTEPAVPPSCG--SGPGAAGALR--MGLGRTQRAARVAVSRALAGTVA 118
           ++R+ P       P   P  G  +GPGAA  L     L  +  AA  AVS    G  A
Sbjct: 167 AARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAA 224



 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 38/101 (37%), Positives = 43/101 (42%), Gaps = 8/101 (7%)

Query: 4   ASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS 63
           A+ A  AP     PPP     P    P    PPSP RP   A P+P   A    PP   S
Sbjct: 76  AAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP--PAAKLRPPPEGS 133

Query: 64  TSSRSPPPRARRT----EPA-VPPSCGSGPGAAGALRMGLG 99
             S +P P A       EPA   P+  +GP AA A R G G
Sbjct: 134 AGSCAPVPAAAAVAAGPEPAPAGPAKPAGP-AALAARAGPG 173



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 41/129 (31%), Positives = 50/129 (38%), Gaps = 17/129 (13%)

Query: 2   AGASAARAAPSPILPP--------PPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAA 53
           A A  A AAPSP   P        PP  PP P   A   G P  P   AP A P P+ A 
Sbjct: 246 AAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP-AVPPPAAA- 303

Query: 54  GPFLPPSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRAL 113
                  +  ++  +P P      PA   S   GPGAA A      + +   RV  +   
Sbjct: 304 ------QNGGSAGAAPAPAPAAGGPA-GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPP 356

Query: 114 AGTVAAAAG 122
           A    AA+G
Sbjct: 357 AAQTLAASG 365



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 48/175 (27%), Positives = 58/175 (33%), Gaps = 59/175 (33%)

Query: 4   ASAARAAPSPILPPPPDLPPT----------PTRRAPLIGCP--------------PSPA 39
           A+ A AAP+   PPPP  P T          P   AP +  P              P+PA
Sbjct: 259 AAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA 318

Query: 40  RPAP---SASPSPSRAAGPFLPPSHASTSSR---SPPPRARR------------------ 75
              P   S  P P  AA    P   A +  R   + PP A+                   
Sbjct: 319 AGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPT 378

Query: 76  ------TEPAVPPSCGSGP-----GAAGALRMGLGRTQRAARVAVSRALAGTVAA 119
                 +  AVPP     P     GAAGA+   L RT  A    +   L  TV A
Sbjct: 379 MQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA 433



 Score = 30.4 bits (67), Expect = 0.85
 Identities = 40/150 (26%), Positives = 50/150 (33%), Gaps = 16/150 (10%)

Query: 22  PPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPPRARR------ 75
           P TP  RA   G   +      S SP+ +  AGP  P   A  ++  PPP  R       
Sbjct: 45  PRTPEVRAAAAG---ALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGG 101

Query: 76  TEPAVPPS-------CGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAAGLGARRA 128
            +   PPS        G  P AA       G     A V  + A+A     A    A+ A
Sbjct: 102 PQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPA 161

Query: 129 RRLHLRGQIGVRRVAGTPEARGRGDGCSLG 158
               L  + G     G     G G G   G
Sbjct: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAG 191


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 58/182 (31%), Positives = 71/182 (39%), Gaps = 28/182 (15%)

Query: 2   AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH 61
           A  +AA AA +P  P P    P   R APL   PP+PA P   A P+  R A    PP+ 
Sbjct: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAP---PPAV 204

Query: 62  ASTSSRSPPPRARRTEP---AVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVA 118
           A+     PPP      P     PP     P   GA+R G      AAR    R +   + 
Sbjct: 205 AAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAG-----GAARPVSLREVVRYLG 259

Query: 119 AAAGLGARRARRLHLRGQIGVRRVAGTPE----ARGRGDGCSLGRVSPDRTPGKGSKGME 174
            + G G R  R           RV G  E    ARGR +   LG ++    P     G  
Sbjct: 260 GSGGAGGRLTR----------GRVQGLLEEEAAARGRLERTRLGALA---LPRGDRPGRA 306

Query: 175 PP 176
           PP
Sbjct: 307 PP 308



 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 34/96 (35%), Positives = 43/96 (44%), Gaps = 11/96 (11%)

Query: 5   SAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPA-RPAPSASPSPSRAAGPFLPPSHAS 63
           +AAR  P P     P  PP   R AP      +P   PAP   P+P  AA P   P  A+
Sbjct: 95  NAARVQP-PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAA 153

Query: 64  TSSRSPP--------PRARRTEP-AVPPSCGSGPGA 90
            ++ +PP        PRA+R  P A PP   + P A
Sbjct: 154 AAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPA 189



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 37/107 (34%), Positives = 45/107 (42%), Gaps = 11/107 (10%)

Query: 25  PTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP--PPRARRTEPAVPP 82
           P RR      PP   R AP+A+ + +    P  PP  A  ++ +P   PRA       PP
Sbjct: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP 160

Query: 83  SCGSGPGAAGALRMGLGRTQRAARVAV-SRALAGTVAAAAGLGARRA 128
           S   GP   G       R QRAA +A    A A   A A   G RRA
Sbjct: 161 S--PGPAQPGP------RAQRAAPLAAPPPAPAAPPAVAPPAGPRRA 199



 Score = 26.9 bits (58), Expect = 9.4
 Identities = 13/35 (37%), Positives = 16/35 (45%), Gaps = 1/35 (2%)

Query: 2   AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPP 36
           A  +    +PSP+ P PP  P  P       GCPP
Sbjct: 417 ASVATGPDSPSPV-PLPPGKPALPGADGTPFGCPP 450


>gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]
          Length = 1516

 Score = 53.9 bits (128), Expect = 7e-08
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 1/91 (1%)

Query: 1   MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60
           +A  +A  + P+P   P    P    R A   G  P  +RP+P  S SP R+ GPF P +
Sbjct: 734 LAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPST 793

Query: 61  HASTS-SRSPPPRARRTEPAVPPSCGSGPGA 90
            +S S S SPPP       ++PP   S P A
Sbjct: 794 DSSASTSCSPPPEQPTATESLPPWSHSCPSA 824


>gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]
          Length = 1516

 Score = 53.9 bits (128), Expect = 7e-08
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 1/91 (1%)

Query: 1   MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60
           +A  +A  + P+P   P    P    R A   G  P  +RP+P  S SP R+ GPF P +
Sbjct: 734 LAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPST 793

Query: 61  HASTS-SRSPPPRARRTEPAVPPSCGSGPGA 90
            +S S S SPPP       ++PP   S P A
Sbjct: 794 DSSASTSCSPPPEQPTATESLPPWSHSCPSA 824


>gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo
           sapiens]
          Length = 402

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 44/133 (33%), Positives = 52/133 (39%), Gaps = 18/133 (13%)

Query: 3   GASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHA 62
           GA +  A P P  PPPP   P P   AP +   P    P P++  +P RAAGP  P    
Sbjct: 14  GAESGDAEPPPQPPPPPPPTPPPGEPAP-VPAAPRYLPPLPASPETPERAAGPSEPLGEV 72

Query: 63  STSSRSPPPRARRTEPAVPP-----SCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTV 117
           +       PR R  +   PP       G    AAG    G  R   AA      A  G  
Sbjct: 73  A-------PRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAA-----AAKGGPG 120

Query: 118 AAAAGLGARRARR 130
            + AG G  R RR
Sbjct: 121 ESEAGAGGERERR 133


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 39/100 (39%), Positives = 44/100 (44%), Gaps = 12/100 (12%)

Query: 8   RAAPSPILPP---PPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSR---AAGPFLPPSH 61
           R AP P  P    PP  PP P    P    PP PAR   +  P PSR   AA P  PPS 
Sbjct: 274 RQAPPPPPPSRGGPPPPPPPPHNSGP----PPPPARGRGAPPPPPSRAPTAAPPPPPPSR 329

Query: 62  ASTSSRSPPPRAR--RTEPAVPPSCGSGPGAAGALRMGLG 99
            S +   PPP        PA+P S  SGP       +G+G
Sbjct: 330 PSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVG 369



 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 28/75 (37%), Positives = 32/75 (42%), Gaps = 8/75 (10%)

Query: 16  PPPP----DLPPTPTRRAPLIGCPPSP-ARPAPSASPSPSRAAGPFLP---PSHASTSSR 67
           PPPP      PP P  RAP    PP P +RP+ +  P P     P  P   PS A +   
Sbjct: 300 PPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPP 359

Query: 68  SPPPRARRTEPAVPP 82
            PPP      P  PP
Sbjct: 360 PPPPSVLGVGPVAPP 374



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 7/83 (8%)

Query: 3   GASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPAR---PAPSASPSPSRAAGPFLPP 59
           GA     + +P   PPP  P  P+   P    PP P R   P P A PS + +  P  PP
Sbjct: 308 GAPPPPPSRAPTAAPPPPPPSRPSVAVP----PPPPNRMYPPPPPALPSSAPSGPPPPPP 363

Query: 60  SHASTSSRSPPPRARRTEPAVPP 82
           S       +PPP      P  PP
Sbjct: 364 SVLGVGPVAPPPPPPPPPPPGPP 386



 Score = 30.8 bits (68), Expect = 0.65
 Identities = 16/43 (37%), Positives = 20/43 (46%), Gaps = 2/43 (4%)

Query: 7   ARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSP 49
           A  + +P  PPPP  PP+     P+   PP P  P P   P P
Sbjct: 349 ALPSSAPSGPPPP--PPSVLGVGPVAPPPPPPPPPPPGPPPPP 389



 Score = 30.8 bits (68), Expect = 0.65
 Identities = 15/40 (37%), Positives = 18/40 (45%), Gaps = 6/40 (15%)

Query: 13  PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRA 52
           P+ PPPP  PP P       G PP P  P+      P+ A
Sbjct: 370 PVAPPPPPPPPPPP------GPPPPPGLPSDGDHQVPTTA 403



 Score = 28.5 bits (62), Expect = 3.2
 Identities = 25/96 (26%), Positives = 34/96 (35%), Gaps = 4/96 (4%)

Query: 5   SAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS- 63
           S+A + P P  PPP  L   P    P    PP P  P P   PS      P    + A+ 
Sbjct: 352 SSAPSGPPP--PPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAAL 409

Query: 64  -TSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGL 98
               R      +  + + P SC         +R G+
Sbjct: 410 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGI 445


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 48/157 (30%), Positives = 67/157 (42%), Gaps = 30/157 (19%)

Query: 1   MAGASAARAAPSP-----ILPPPPDL--PPTPTRRAPLIGCPPSPARPAPSASPSPSRAA 53
           + G +  R+ P P     I PPPP    PP P R  P    PP+  R  P   P P  A 
Sbjct: 331 IVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPG-AG 389

Query: 54  GPFL-------PPSHASTSSRSPPPRARRTEPAVPPSCGSGPGAA-GAL----RMGL--- 98
           GP +       PP  +S +  +PPP      PA+ P+ G  PG   GAL    R G+   
Sbjct: 390 GPPMPPPPPPPPPPPSSGNGPAPPP----LPPALVPAGGLAPGGGRGALLDQIRQGIQLN 445

Query: 99  ---GRTQRAARVAVSRALAGTVAAAAGLGARRARRLH 132
              G  + +A     ++  G V A   +  +R+R +H
Sbjct: 446 KTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIH 482



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 36/116 (31%), Positives = 41/116 (35%), Gaps = 31/116 (26%)

Query: 16  PPPPDLPPTPTRRAPLIG--------CPPSP---ARPAPS--ASPSPSRAAGPFLPPSHA 62
           PPPP        R P++G         PP P   A P P+    P P R   P  PP   
Sbjct: 316 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPAT 375

Query: 63  STSSRSPPPRARRTEPAV---------PPSCGSGPG---------AAGALRMGLGR 100
             S   PPP      P +         PPS G+GP           AG L  G GR
Sbjct: 376 GRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGR 431


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 50.4 bits (119), Expect = 8e-07
 Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 7/93 (7%)

Query: 7    ARAAPSPILPPPPDLPPTPTRRAPLIGCP-----PSPARPAPSASPSPSRAAGPFLPPSH 61
            A   P P+ P PP  P  P     + G P     PSPA P+P+  P  + A  P  PPS 
Sbjct: 1263 AHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPA-PSPARQPPAALAKPPGTPPSL 1321

Query: 62   ASTSSRSPPPRARRTE-PAVPPSCGSGPGAAGA 93
             ++ ++ P P A     PA PP   +   AA A
Sbjct: 1322 GASPAKPPSPGAPALHVPAKPPRAAAAAAAAAA 1354



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 42/130 (32%), Positives = 54/130 (41%), Gaps = 26/130 (20%)

Query: 10   APSPILPPP-PDLP--PTPT-RRAPLIGC-------------PPSPARPAPSASPSPSRA 52
            +P P+L  P P L   PTPT ++ PL G              P SP  P P  +P P +A
Sbjct: 1227 SPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKA 1286

Query: 53   AGPFLPPSHASTSSRSP---PPRARRTEPAVPPSCGSGPG-----AAGALRMGLGRTQRA 104
                   S   + + SP   PP A    P  PPS G+ P       A AL +   +  RA
Sbjct: 1287 VAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVP-AKPPRA 1345

Query: 105  ARVAVSRALA 114
            A  A + A A
Sbjct: 1346 AAAAAAAAAA 1355



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 33/100 (33%), Positives = 41/100 (41%), Gaps = 15/100 (15%)

Query: 5    SAARAAPSPILPPPPDLPPTPTRRAPLIGCPP------SPARPAPSASPSPSRAAGPFLP 58
            ++ +A P  + PPPP   P PT  A L   PP       PA+P  S  P  ++   P L 
Sbjct: 1182 ASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPV-PKLQ 1240

Query: 59   PSHASTSSRSPPP--------RARRTEPAVPPSCGSGPGA 90
             S   TS + P P        RA  T P V P     P A
Sbjct: 1241 GSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTA 1280



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 11/90 (12%)

Query: 1    MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPS-PARPAPSASPSPSRAAGPFLPP 59
            +AG  +  A PSP  P P   PP    + P  G PPS  A PA   SP       P  PP
Sbjct: 1287 VAGLPSGSAGPSPA-PSPARQPPAALAKPP--GTPPSLGASPAKPPSPGAPALHVPAKPP 1343

Query: 60   SHASTSSRSPPPRARRTEPAVPPSCGSGPG 89
              A+ ++      A    P  PP  G+ PG
Sbjct: 1344 RAAAAAA------AAAAAPPAPPE-GASPG 1366



 Score = 34.3 bits (77), Expect = 0.059
 Identities = 34/125 (27%), Positives = 47/125 (37%), Gaps = 27/125 (21%)

Query: 5   SAARAAPSP-ILPP------PPDLPPTPTRRAPLIGCPP------SPARPAPSASPSPSR 51
           + A+  P+P +LPP      P  LP +PT R      P        PA P P+  P P+ 
Sbjct: 800 ATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTA 859

Query: 52  AAGPFLPP------------SHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLG 99
                LPP            +H+     +      R E  VP    +GP A    R+G  
Sbjct: 860 VPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVP--AAAGPYATVQRRVGRS 917

Query: 100 RTQRA 104
            + RA
Sbjct: 918 HSVRA 922



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 23/83 (27%), Positives = 28/83 (33%), Gaps = 15/83 (18%)

Query: 11  PSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPP 70
           P+P  PP    P            PP P +P               LPP    TS  +PP
Sbjct: 733 PAPGTPPREARPGRHGHSIKRASVPPVPGKPR------------QVLPP---GTSHFTPP 777

Query: 71  PRARRTEPAVPPSCGSGPGAAGA 93
               +T P  P + G   G A A
Sbjct: 778 QTPTKTRPGSPQALGGPHGPAPA 800


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 43/145 (29%), Positives = 55/145 (37%), Gaps = 29/145 (20%)

Query: 16  PPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPPRARR 75
           PPPP LPP P + +  +  PP P  P P   PS     GP  PP         PPP   +
Sbjct: 314 PPPPPLPPGPAQAS--VALPPPPGPPPPPPLPS----TGPPPPP--------PPPPLPNQ 359

Query: 76  TEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAAGLGARRARRLHLR- 134
             P  PP       A+G     +           +R L G  AA AG   R+  R+    
Sbjct: 360 VPPPPPPPPAPPLPASGFFLASMSED--------NRPLTGLAAAIAGAKLRKVSRMEDTS 411

Query: 135 -----GQIGVRRVAGTPEARGRGDG 154
                  IGV   +   +  GRG+G
Sbjct: 412 FPSGGNAIGVNSASSKTDT-GRGNG 435



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 15/32 (46%), Positives = 17/32 (53%)

Query: 11  PSPILPPPPDLPPTPTRRAPLIGCPPSPARPA 42
           PS   PPPP  PP P +  P    PP+P  PA
Sbjct: 343 PSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPA 374


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 43/145 (29%), Positives = 55/145 (37%), Gaps = 29/145 (20%)

Query: 16  PPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPPRARR 75
           PPPP LPP P + +  +  PP P  P P   PS     GP  PP         PPP   +
Sbjct: 314 PPPPPLPPGPAQAS--VALPPPPGPPPPPPLPS----TGPPPPP--------PPPPLPNQ 359

Query: 76  TEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAAGLGARRARRLHLR- 134
             P  PP       A+G     +           +R L G  AA AG   R+  R+    
Sbjct: 360 VPPPPPPPPAPPLPASGFFLASMSED--------NRPLTGLAAAIAGAKLRKVSRMEDTS 411

Query: 135 -----GQIGVRRVAGTPEARGRGDG 154
                  IGV   +   +  GRG+G
Sbjct: 412 FPSGGNAIGVNSASSKTDT-GRGNG 435



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 15/32 (46%), Positives = 17/32 (53%)

Query: 11  PSPILPPPPDLPPTPTRRAPLIGCPPSPARPA 42
           PS   PPPP  PP P +  P    PP+P  PA
Sbjct: 343 PSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPA 374


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 38/106 (35%), Positives = 44/106 (41%), Gaps = 12/106 (11%)

Query: 3   GASAARAAPSPILPPPPDLPPT-PTRRAPLIGCP-PSPARPAPSASPSPSRAAGPFLPPS 60
           GA+     P P LP P + PP+ P +  PL G P P PA P P   P P     P  PP 
Sbjct: 539 GAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPP-----PPPPPP 593

Query: 61  HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAAR 106
              T    PPP      P  PP  G  P A G     LG   +A +
Sbjct: 594 PPGTDGPVPPP-----PPPPPPPPGGPPDALGRRDSELGPGVKAKK 634



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 32/91 (35%), Positives = 36/91 (39%), Gaps = 18/91 (19%)

Query: 10  APSPILP---PPPDLPP--------TPTRRAPLIGCPPSPARPAPSASP-SPSRAAGPFL 57
           AP+P +P   P PDL P         P    PL G  PSP    PSA P +P     P  
Sbjct: 516 APTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGL-PSPQEAPPSAPPQAPPLPGSPEP 574

Query: 58  PPSHASTSSRSPPPRARRTEPAVPPSCGSGP 88
           PP+        PPP      P  PP    GP
Sbjct: 575 PPAPPLPGDLPPPP-----PPPPPPPGTDGP 600



 Score = 31.2 bits (69), Expect = 0.50
 Identities = 20/68 (29%), Positives = 22/68 (32%), Gaps = 6/68 (8%)

Query: 11  PSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPP 70
           P P  P P DLPP P         PP P    P   P P     P  PP           
Sbjct: 574 PPPAPPLPGDLPPPPPPP------PPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELG 627

Query: 71  PRARRTEP 78
           P  +  +P
Sbjct: 628 PGVKAKKP 635



 Score = 29.6 bits (65), Expect = 1.4
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 9/62 (14%)

Query: 30  PLIGCPPSPARP--------APSASPSPSRAAGPFLPPSHASTSSRSPPPRARRTEPAVP 81
           P  G  P+P  P        AP+A P+P  AA P  PP     S +  PP A    P +P
Sbjct: 511 PSGGDAPTPGVPTGSPSPDLAPAAEPAPG-AAPPPPPPLPGLPSPQEAPPSAPPQAPPLP 569

Query: 82  PS 83
            S
Sbjct: 570 GS 571


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 32/79 (40%), Positives = 38/79 (48%), Gaps = 7/79 (8%)

Query: 7   ARAAPSP---ILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS 63
           AR  P P     P P  LPP+P    PL   PPSP+ P PS    PS    P  PPS A 
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP-PSLQTLPS---PPATPPSQAP 369

Query: 64  TSSRSPPPRARRTEPAVPP 82
            S  +PP +A  +   +PP
Sbjct: 370 PSMTTPPMQAPPSLQTIPP 388



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 10/85 (11%)

Query: 8   RAAPSPILPPPPDLPPTPTRRAPL----------IGCPPSPARPAPSASPSPSRAAGPFL 57
           +A PSP   PP     TP+ +AP              PPSP   AP + P+    +    
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690

Query: 58  PPSHASTSSRSPPPRARRTEPAVPP 82
           PPS A  S  +PP +   + PA PP
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPP 715



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 58/198 (29%), Positives = 77/198 (38%), Gaps = 30/198 (15%)

Query: 2   AGASA---ARAAPSPILPPPP--DLPPTPTRRAPL--------IGCPPSPARPAPSASPS 48
           AGA+A   A  AP  + P PP    PP P   A L        +G  P   R       +
Sbjct: 10  AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69

Query: 49  PSRAAGPFLPPSHASTSSRSP---PPRARRTEPAVPPSCGSGPG-------AAGALRMG- 97
              +A    P   A TSSR+P   PP + R E A PP+  + PG       A+G  R G 
Sbjct: 70  IPESAPRAGPTRSAGTSSRNPASRPPASGRGERA-PPAKNTSPGPVSSPGRASGTTRPGP 128

Query: 98  LGRTQRAARVAVSRALA---GTVAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDG 154
           LG  Q+  R++    +A    T A      +  ARR       G    A    +R  G  
Sbjct: 129 LG--QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186

Query: 155 CSLGRVSPDRTPGKGSKG 172
             L R +P   P   ++G
Sbjct: 187 VGLPRPAPSARPRPPTEG 204



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 29/91 (31%), Positives = 37/91 (40%), Gaps = 13/91 (14%)

Query: 12  SPILPPPPDLPPTPTRRAPLIGCPPSP-ARP--APSASPSPSR--------AAGPFLPPS 60
           SP+  PPP  PP      P +  PPSP A P  +P A+PSP             PF PP 
Sbjct: 612 SPLATPPPQAPPXLA--LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669

Query: 61  HASTSSRSPPPRARRTEPAVPPSCGSGPGAA 91
                +   PP +    P+  P   + P  A
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 4/77 (5%)

Query: 10  APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASP---SPSRAAGPF-LPPSHASTS 65
           AP P+  PP  L   P      I  PP  A PA ++ P    PS    P   PP  A   
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624

Query: 66  SRSPPPRARRTEPAVPP 82
              PP +A  + PA PP
Sbjct: 625 LALPPLQAPPSPPASPP 641



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 34/94 (36%), Positives = 44/94 (46%), Gaps = 12/94 (12%)

Query: 4   ASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPF-LPPSHA 62
           A A     +P  PPP   PP     +P    P SP+   PS +P PS AA P  +PPS  
Sbjct: 655 ALAVHLLQAPFSPPPS--PPVQAPFSPPASPPVSPSATPPSQAP-PSLAAPPLQVPPSPP 711

Query: 63  STS----SRSPPPRARRTEPA----VPPSCGSGP 88
           ++     S +PPP+A     A    VPPS  + P
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 10/86 (11%)

Query: 4   ASAARAAPSPILPPPPDLPPTPTRRAPLI-GCPPSPARPAPSASPSPSRAAGPFLPPSHA 62
           A+    AP  +  PP  +PP+P    P+     P P  P P A+P       P  P S  
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP--PASPP 746

Query: 63  STSSRSPPPRARRTEPAVPPSCGSGP 88
            + S +PPPR       VPP   + P
Sbjct: 747 MSPSATPPPR-------VPPLLAAPP 765



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 7/75 (9%)

Query: 12  SPILPPP-PDLPPT---PTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSR 67
           +P  PP  P + P+   P++  P +  PP    P+P ASP  S +A    PP  A     
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA---TPPPQAPPPLA 731

Query: 68  SPPPRARRTEPAVPP 82
           +PP +   + PA PP
Sbjct: 732 APPLQVPPSPPASPP 746



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 32/88 (36%), Positives = 37/88 (42%), Gaps = 17/88 (19%)

Query: 12  SPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPP 71
           SP+  PPP  PP     APL+  PPSP      ASP+      P  PP+    +S S P 
Sbjct: 822 SPLATPPPQAPPVLA--APLLQVPPSP-----PASPT---LQAPRRPPTPGPDTSVSGPR 871

Query: 72  RARRTEPAVPP-------SCGSGPGAAG 92
                 P  PP       S  SGP  AG
Sbjct: 872 LTLALAPGPPPPPSRSPSSTLSGPDLAG 899



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 38/121 (31%), Positives = 47/121 (38%), Gaps = 12/121 (9%)

Query: 2   AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH 61
           AGA    + P+P  P P        RR+   G      RPAPSA P P    GP    S 
Sbjct: 158 AGARRDTSGPTPGTPSP-----AMARRSRAAGTEVGLPRPAPSARPRPP-TEGPRKSVSS 211

Query: 62  AST-SSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAA 120
           AS  S+  P P ARR      PS G G     +  +    T  ++      +  GT  A 
Sbjct: 212 ASEHSTTEPSPAARRR-----PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 121 A 121
           A
Sbjct: 267 A 267



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 32/96 (33%), Positives = 41/96 (42%), Gaps = 14/96 (14%)

Query: 3   GASAARAAPSPILPP------PPDLPPTPTRRAPLIGCPPSPARPAPSASPSPS-RAAGP 55
           G   A A PS   P       PP + P     AP +G    P   +P A+PSPS   A P
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG----PLSSSPLATPSPSGTKARP 316

Query: 56  FLPPSHAST---SSRSPPPRARRTEPAVPPSCGSGP 88
             PP +A+T   ++  P P      P  PPS  + P
Sbjct: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 9   AAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPF-LPPSHASTSSR 67
           A P P  PPP   PP     +P    P SP+   P   P P  AA P  +PPS  ++   
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP-PLLAAPPLQVPPSPPASLPM 778

Query: 68  SPPPRARRTEPAVPPSCGSGP 88
           SP     +  P  PP+  + P
Sbjct: 779 SP---LAKPPPQAPPALATPP 796



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 10/73 (13%)

Query: 12  SPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSR-----AAGPFLPPSHASTSS 66
           +P+L  PP  P +PT +A     P  P  P P  S S  R     A GP  PPS + +S+
Sbjct: 837 APLLQVPPSPPASPTLQA-----PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891

Query: 67  RSPPPRARRTEPA 79
            S P  A  +  A
Sbjct: 892 LSGPDLAGHSSSA 904



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 19/94 (20%)

Query: 9   AAPSPILPPPPDLPP--------------TPTRRAPLIGCPPSPARPAPSASP--SPSRA 52
           A P P  PP    PP               P +  P +  PP  A P+P ASP  SP   
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647

Query: 53  AGPFLPPS---HASTSSRSPPPRARRTEPAVPPS 83
             P  P +   H   +  SPPP      P  PP+
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 25/84 (29%), Positives = 30/84 (35%), Gaps = 5/84 (5%)

Query: 10  APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASP----SPSRAAGPF-LPPSHAST 64
           AP  +  PP  L   P    P +  PP     AP  +P     P  A  P   PPS  +T
Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT 578

Query: 65  SSRSPPPRARRTEPAVPPSCGSGP 88
                P       P  PP+  S P
Sbjct: 579 PPPETPSSIATPPPQAPPALASPP 602



 Score = 36.2 bits (82), Expect = 0.015
 Identities = 32/100 (32%), Positives = 42/100 (42%), Gaps = 20/100 (20%)

Query: 9   AAPSPILPP-----PPDLPPTPTRRAPLI-------GCPPSPARPAPSASPSPSRA---A 53
           A P P +PP     P  +PP+P    P+          PP+ A P   A PSP  +    
Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ 810

Query: 54  GPFLPPSHASTSS-RSPPPRARRTEPA----VPPSCGSGP 88
            PF P +    S   +PPP+A     A    VPPS  + P
Sbjct: 811 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850



 Score = 35.4 bits (80), Expect = 0.026
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 9   AAPSPILPPPPDLPPT----PTRRA-PLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS 63
           A P P+ PP P  PP+    P+  A P    PPS   P   A PS        +P S  S
Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397

Query: 64  TSSRSPPPRARRTEPAVPPSCGS 86
            S ++PP     +      S GS
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGS 420



 Score = 35.4 bits (80), Expect = 0.026
 Identities = 26/81 (32%), Positives = 32/81 (39%), Gaps = 10/81 (12%)

Query: 8   RAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSR 67
           +A PSP+  PPP+ P +       I  PP  A   P A  SP     P  P S  +T   
Sbjct: 570 QAPPSPLTTPPPETPSS-------IATPPPQA---PPALASPPLQGLPSPPLSPLATPPP 619

Query: 68  SPPPRARRTEPAVPPSCGSGP 88
             PP         PPS  + P
Sbjct: 620 QAPPXLALPPLQAPPSPPASP 640



 Score = 35.4 bits (80), Expect = 0.026
 Identities = 35/102 (34%), Positives = 40/102 (39%), Gaps = 17/102 (16%)

Query: 12  SPILPPPPDLPPTPTRRAPLIGCPPSPA--------RPAPSASPSPSRAAGPFLPPSHAS 63
           SP+  PPP  PP      PL   P  PA         P+ S   SP     P  PP  A+
Sbjct: 779 SPLAKPPPQAPPA-LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837

Query: 64  TSSRSPP-PRARRT--EPAVPPSCG-----SGPGAAGALRMG 97
              + PP P A  T   P  PP+ G     SGP    AL  G
Sbjct: 838 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 9/81 (11%)

Query: 5   SAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAST 64
           +A+    +P L  PP   P P      +  PPSP    P  +PS      P  PP+ AS 
Sbjct: 548 TASAPLTTPHLETPPCPAPCP------LQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601

Query: 65  SSR---SPPPRARRTEPAVPP 82
             +   SPP     T P   P
Sbjct: 602 PLQGLPSPPLSPLATPPPQAP 622



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 30/95 (31%), Positives = 37/95 (38%), Gaps = 17/95 (17%)

Query: 11  PSPILPPPPDLPPT--PTRRAPLIGCPPS--PARPAP-----------SASPSPSRAAG- 54
           P  + PP  D  P   P   +PL    PS   ARP P           +  PSP  A   
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341

Query: 55  PFLPPSHASTSSRSPPPRARRTEPA-VPPSCGSGP 88
           P  PPS ++  S    P    T P+  PPS  + P
Sbjct: 342 PLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376



 Score = 31.2 bits (69), Expect = 0.50
 Identities = 26/69 (37%), Positives = 28/69 (40%), Gaps = 5/69 (7%)

Query: 6    AARAAPSPILPPPPDLPPTPTRRAPLIGCPPSP--ARPAPSA---SPSPSRAAGPFLPPS 60
            A R AP   LP PP   P        I     P  A PAP A    PSP  + G     +
Sbjct: 949  AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGA 1008

Query: 61   HASTSSRSP 69
             A  SSRSP
Sbjct: 1009 GAGASSRSP 1017



 Score = 30.8 bits (68), Expect = 0.65
 Identities = 33/111 (29%), Positives = 39/111 (35%), Gaps = 39/111 (35%)

Query: 11  PSPILPPPPDLPP---TPTRRAPL-------IGCPPSPARPAPSASPSP---------SR 51
           PSP   PP   PP   TP  +AP        I  P S   P+  A PSP         + 
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417

Query: 52  AAGPFLPPSH--------------------ASTSSRSPPPRARRTEPAVPP 82
              P L  +H                    AST   SPP +A  + PA PP
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 16/88 (18%)

Query: 11  PSPILPPPPDLPPTPTRRAPL-----IGCPPSPA---------RPAPSASPSPSRAAG-- 54
           P  +  P    PP+P   + L     +G P   A         R   ++  SPSR A   
Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP 451

Query: 55  PFLPPSHASTSSRSPPPRARRTEPAVPP 82
           P  PP  A  S  + PP      PAV P
Sbjct: 452 PDSPPLQAPLSLPASPPLQTSLSPAVSP 479



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 33/113 (29%), Positives = 42/113 (37%), Gaps = 23/113 (20%)

Query: 3   GASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSR----------- 51
           G   + + P   L   P  PP P+R        P  A  + SA+ +P             
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921

Query: 52  -AAGPFLPPS------HASTSSRSP-PPRARRTEPAVPPSC--GSGPGAAGAL 94
            AA P  PP       H +  SR P PP A R  P  P      +GPG+A  L
Sbjct: 922 AAASP--PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972



 Score = 28.5 bits (62), Expect = 3.2
 Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 37  SPARPAPSASPSPSRAAGPFLPPSHASTSSRSP---PPRARRTEPAVPPSCGS 86
           SPAR  PSA  +P   A P  P      + R P   PPR +   PA+ P   S
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-KDAAPALGPLSSS 302


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 34/87 (39%), Positives = 38/87 (43%), Gaps = 10/87 (11%)

Query: 12  SPILPPPPDLPPTPTRRAPLIGCPP--SPARPAPSASP-SPSRAAGPFLPPSHAS----- 63
           SP+ PPP +LP +P   A  +  PP  SP  P P  SP SP   A    PP   S     
Sbjct: 552 SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611

Query: 64  --TSSRSPPPRARRTEPAVPPSCGSGP 88
              S  SPPP A R  P    S  S P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPP 638



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 31/84 (36%), Positives = 34/84 (40%), Gaps = 7/84 (8%)

Query: 12  SPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSS----- 66
           SP+ PPP   P +P   +PL     SP  PA     SP   A P  PP   S  S     
Sbjct: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE 560

Query: 67  --RSPPPRARRTEPAVPPSCGSGP 88
              SPPP A R  P    S  S P
Sbjct: 561 LPTSPPPEASRLSPPPEESPMSPP 584



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 32/98 (32%), Positives = 37/98 (37%), Gaps = 23/98 (23%)

Query: 12  SPILPPPPDLPPTPTRRAPLIGCPP--SPARPAPSASP-------------------SPS 50
           SP+ PPP + P +P   A  +  PP  SP  P P  SP                   SP 
Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP 665

Query: 51  RAAGPFLPPSHASTSSRSPPPRARRTEPAVPPSCGSGP 88
               P  PP   S +  SPPP A R  P    S  S P
Sbjct: 666 PEESPLSPPPEESPT--SPPPEASRLSPPPEDSPTSPP 701



 Score = 41.2 bits (95), Expect = 5e-04
 Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 12  SPILPPPPDLPPTPTRRAPLIGCP--PSPARPAPSASP-SPSRAAGPFLP--PSHASTSS 66
           S + PPP +LP +P   A  +  P   SP  P P  SP SP   + PF P   S  S   
Sbjct: 465 SRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE 524

Query: 67  RSPPPRARRTEPAVPP 82
            SPP  A  T  + PP
Sbjct: 525 ESPPSPALETPLSPPP 540



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 32/90 (35%), Positives = 39/90 (43%), Gaps = 9/90 (10%)

Query: 6   AARAAP----SPILPPPPDLPPTPTRRAPLIGCPPSPAR--PAPSASP-SPSRAAGPFLP 58
           A+R +P    SP+ PPP + P +P      +   P  +R  P P  SP SP     P  P
Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682

Query: 59  PSHASTSSRSPPPRARRTEPAVPPSCGSGP 88
           P  A  S  SPPP    T P    S  S P
Sbjct: 683 PPEA--SRLSPPPEDSPTSPPPEDSPASPP 710



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 30/83 (36%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 9   AAPSPILPPPPDLPPTPTRRAPLIGCPPS--PARPAPSASP-SPSRAAGPFLPPSHASTS 65
           A  +P+ PPP   P +P      +  PP   P  P P AS  SP     P  PP     S
Sbjct: 531 ALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP--PEES 588

Query: 66  SRSPPPRARRTEPAVPPSCGSGP 88
             SPPP A R  P    S  S P
Sbjct: 589 PMSPPPEASRLFPPFEESPLSPP 611



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 28/79 (35%), Positives = 34/79 (43%), Gaps = 11/79 (13%)

Query: 12  SPILPPPPDLPPTPT-RRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS------- 63
           SP+ PPP + P +P    +P      SP  P   + PSP+    P  PP  AS       
Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET-PLSPPPEASPLSPPFE 550

Query: 64  TSSRSPPPRARRTEPAVPP 82
            S  SPPP    T P  PP
Sbjct: 551 ESPLSPPPEELPTSP--PP 567



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 28/87 (32%), Positives = 35/87 (40%), Gaps = 10/87 (11%)

Query: 6   AARAAP----SPILPPPPDLPPTPTRRAPLIGCP--PSPARPAPSASPSPSRAAGPFLPP 59
           A+R +P    SP  PPP D P +P     L+  P   SP  P P       R+ GP L P
Sbjct: 686 ASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP 745

Query: 60  ----SHASTSSRSPPPRARRTEPAVPP 82
                H S     P    +  EP + P
Sbjct: 746 RPEEPHLSPRPEEPHLSPQAEEPHLSP 772



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 31/92 (33%), Positives = 36/92 (39%), Gaps = 16/92 (17%)

Query: 9    AAPSPILPPPPDLPPTPTRRAPLIG---------CPPSPARPAPSASPSPSRAAGPFLPP 59
            A P P  PP    PP      P++G          P  P RP+   SPS        LPP
Sbjct: 4279 AGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPP 4338

Query: 60   SHASTSSRSPPPRARRTEPAVPPSCGSGPGAA 91
            +H  T    P P+    EP  PP   S P AA
Sbjct: 4339 THPGT----PKPQGPTLEP--PPGRVS-PAAA 4363



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 5/83 (6%)

Query: 6    AARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPP--SHAS 63
            AA    +PI PPP      P    P+I  PPSP  P   ASP       P   P   H+ 
Sbjct: 974  AAPILETPISPPPEANCTDPEPVPPMI-LPPSPGSPVGPASPILMEPLPPQCSPLLQHSL 1032

Query: 64   TSSRSPPPRARRTEPAVPPSCGS 86
                SPP +   + PA+P S  S
Sbjct: 1033 VPQNSPPSQC--SPPALPLSVPS 1053



 Score = 35.8 bits (81), Expect = 0.020
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 6/77 (7%)

Query: 12   SPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPP 71
            +P+ P    + P    ++P +G  P    PA + +PSP      F P S+  T   + PP
Sbjct: 2329 APLTPRASQVEP----QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSY--TDPYAQPP 2382

Query: 72   RARRTEPAVPPSCGSGP 88
               R +P  P SC + P
Sbjct: 2383 LTPRPQPPPPESCCALP 2399



 Score = 35.4 bits (80), Expect = 0.026
 Identities = 29/86 (33%), Positives = 35/86 (40%), Gaps = 15/86 (17%)

Query: 12  SPILPPPPDLPPTPTRRAPLIGCPP--SPARPAPS---ASPSPSRA-------AGPFLP- 58
           SP+ PPP + P +P   A  +  PP  SP  P P    ASP P  +         P LP 
Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728

Query: 59  PSHASTSSRSPPPR--ARRTEPAVPP 82
           P       RS  P    R  EP + P
Sbjct: 729 PEEPQLCPRSEGPHLSPRPEEPHLSP 754



 Score = 35.0 bits (79), Expect = 0.034
 Identities = 49/185 (26%), Positives = 64/185 (34%), Gaps = 20/185 (10%)

Query: 10   APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLP-PSHASTSSRS 68
            A  P+ P P   PP      P    P  P    P++  S S +  P  P P  A     S
Sbjct: 2379 AQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPS 2438

Query: 69   P-PPRARRTEP-AVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAAGLGAR 126
            P  PR +  +P + PPS          L     R Q       + +LA T   A G  A 
Sbjct: 2439 PVTPRFQSPDPYSRPPSRPQSRDPFAPLHKP-PRPQPPEVAFKAGSLAHTSLGAGGFPA- 2496

Query: 127  RARRLHLRGQIGVRRVAGTPE--ARGRGDGCSLGRVSPDR------------TPGKGSKG 172
             A      G++  +  +G P    R  G G  +G  SP R             P     G
Sbjct: 2497 -ALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG 2555

Query: 173  MEPPH 177
            + PPH
Sbjct: 2556 LPPPH 2560



 Score = 33.5 bits (75), Expect = 0.100
 Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 12/75 (16%)

Query: 13  PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS-HAS----TSSR 67
           P+LPPP + P +P    P    P SP   A   SP P       LP + H S     S  
Sbjct: 439 PLLPPPEESPLSP----PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL 494

Query: 68  SPPPRARRTEPAVPP 82
           SPPP      P  PP
Sbjct: 495 SPPP---EESPLSPP 506



 Score = 33.5 bits (75), Expect = 0.100
 Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 14/73 (19%)

Query: 9    AAPSPILPPPPDLPPTPTRRA----PLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAST 64
            +AP P  P PP  P  P+  +    PL+  P  P    P  SP P            +S 
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLA----------SSP 4956

Query: 65   SSRSPPPRARRTE 77
             S  P PRAR  E
Sbjct: 4957 ESARPKPRARPPE 4969



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 33/113 (29%), Positives = 43/113 (38%), Gaps = 31/113 (27%)

Query: 13   PILPPPPDLPPTPTRRAPLIG--CPPSPARPAPSASPSPSRAAGPFLPP----------- 59
            P+ P P +LP +P+    L     PP P    P  SP  + AA P L P           
Sbjct: 907  PLSPLPEELPLSPSGEPSLSPQLMPPDPL--PPPLSPIITAAAPPALSPLGELEYPFGAK 964

Query: 60   ----------SHASTSSRSPPPRARRTEP------AVPPSCGSGPGAAGALRM 96
                      +    +  SPPP A  T+P       +PPS GS  G A  + M
Sbjct: 965  GDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILM 1017



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 25/89 (28%), Positives = 33/89 (37%), Gaps = 3/89 (3%)

Query: 4    ASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS 63
            A  + +A   + PP   +P   +     +  PP      PS  P     A P L P   +
Sbjct: 2133 AGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYP-LEPRFPT 2191

Query: 64   TSSRSPPPRARRTEPAVPPSCG--SGPGA 90
                 PP  +    PA PP  G  S PGA
Sbjct: 2192 APPTYPPYPSPTGAPAQPPMLGASSRPGA 2220



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 30/118 (25%), Positives = 42/118 (35%), Gaps = 20/118 (16%)

Query: 2    AGASAARAAPSPI-LPPPPDLPPTPTRRAPLIGCPPSPARPA-----PSASPSPSRAAGP 55
            AG+     +P  + L  PP +P     + P    P  P  P      P+  P PS    P
Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206

Query: 56   FLPPSHASTSS---------RSPPPRARRTEPAVP-----PSCGSGPGAAGALRMGLG 99
              PP   ++S           + PP   R +P+ P     P C S    A     G+G
Sbjct: 2207 AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG 2264



 Score = 28.5 bits (62), Expect = 3.2
 Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 12/86 (13%)

Query: 32   IGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP-----------PPRARRTEPAV 80
            +G  P P  P    +P  + + GP L P H +    SP           P     TE  +
Sbjct: 4277 LGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQL 4336

Query: 81   PPSCGSGPGAAG-ALRMGLGRTQRAA 105
            PP+    P   G  L    GR   AA
Sbjct: 4337 PPTHPGTPKPQGPTLEPPPGRVSPAA 4362



 Score = 27.7 bits (60), Expect = 5.5
 Identities = 28/105 (26%), Positives = 37/105 (35%), Gaps = 20/105 (19%)

Query: 2    AGASAARAAPSPILPPPPDLP----------PTPTRRAPLI-------GCPPSPARP--A 42
            A  +     P  ILPP P  P          P P + +PL+         PPS   P   
Sbjct: 988  ANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL 1047

Query: 43   PSASPSPSRAAGPFLPPSHASTSSRSPPPRARRTE-PAVPPSCGS 86
            P + PSP    G  +  S  +        +    E PA+ PS  S
Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATS 1092


>gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo
           sapiens]
          Length = 355

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 59/171 (34%), Positives = 66/171 (38%), Gaps = 17/171 (9%)

Query: 10  APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP 69
           A SP LP P D  P     AP        + P   A    SRA G     + A +SSR P
Sbjct: 97  ASSPRLPLPADSEPDAYTSAP------RGSGPTYCAGAGNSRAGGGLTKYNSAHSSSRVP 150

Query: 70  PPRARRTEPAVPPSCGSGPG-AAGALRMGLGRTQRAARVAVSRALAGTVAAAAG---LGA 125
            PR          SCG GPG  + A R GLG   R+AR    R    T     G    GA
Sbjct: 151 RPRLPSQRRGA--SCGLGPGPESRAARQGLG--GRSARARTRRGPHRTRRPEPGPHHTGA 206

Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPP 176
           R+A    L G  G  R AGT  A  RG    L   S          G+ PP
Sbjct: 207 RQAG--PLPGTRGRTRAAGTGSA-ARGPARHLRGGSVAAAAAARCLGLSPP 254



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 22/167 (13%)

Query: 21  LPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH---------ASTSSRSPPP 71
           L PTP+     + C PSP   A S    P + + PFLP S          +S  SR P P
Sbjct: 21  LHPTPSEA---LSCWPSPPGEAYSLPELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSP 77

Query: 72  RARRTEPAVPPSCGSGPGAAGALRMGLGRTQR------AARVAVSRALAGTVAAAAGLGA 125
               T P   P    G   A + R+ L           A R +     AG   + AG G 
Sbjct: 78  AHPWTTPQPGPPHQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGL 137

Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKG 172
            +    H   ++   R+   P  R RG  C LG     R   +G  G
Sbjct: 138 TKYNSAHSSSRVPRPRL---PSQR-RGASCGLGPGPESRAARQGLGG 180


>gi|239748667 PREDICTED: hypothetical protein XP_002346761 [Homo
           sapiens]
          Length = 355

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 59/171 (34%), Positives = 66/171 (38%), Gaps = 17/171 (9%)

Query: 10  APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP 69
           A SP LP P D  P     AP        + P   A    SRA G     + A +SSR P
Sbjct: 97  ASSPRLPLPADSEPDAYTSAP------RGSGPTYCAGAGNSRAGGGLTKYNSAHSSSRVP 150

Query: 70  PPRARRTEPAVPPSCGSGPG-AAGALRMGLGRTQRAARVAVSRALAGTVAAAAG---LGA 125
            PR          SCG GPG  + A R GLG   R+AR    R    T     G    GA
Sbjct: 151 RPRLPSQRRGA--SCGLGPGPESRAARQGLG--GRSARARTRRGPHRTRRPEPGPHHTGA 206

Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPP 176
           R+A    L G  G  R AGT  A  RG    L   S          G+ PP
Sbjct: 207 RQAG--PLPGTRGRTRAAGTGSA-ARGPARHLRGGSVAAAAAARCLGLSPP 254



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 22/167 (13%)

Query: 21  LPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH---------ASTSSRSPPP 71
           L PTP+     + C PSP   A S    P + + PFLP S          +S  SR P P
Sbjct: 21  LHPTPSEA---LSCWPSPPGEAYSLPELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSP 77

Query: 72  RARRTEPAVPPSCGSGPGAAGALRMGLGRTQR------AARVAVSRALAGTVAAAAGLGA 125
               T P   P    G   A + R+ L           A R +     AG   + AG G 
Sbjct: 78  AHPWTTPQPGPPHQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGL 137

Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKG 172
            +    H   ++   R+   P  R RG  C LG     R   +G  G
Sbjct: 138 TKYNSAHSSSRVPRPRL---PSQR-RGASCGLGPGPESRAARQGLGG 180


>gi|239742692 PREDICTED: hypothetical protein XP_002342583 [Homo
           sapiens]
          Length = 355

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 59/171 (34%), Positives = 66/171 (38%), Gaps = 17/171 (9%)

Query: 10  APSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP 69
           A SP LP P D  P     AP        + P   A    SRA G     + A +SSR P
Sbjct: 97  ASSPRLPLPADSEPDAYTSAP------RGSGPTYCAGAGNSRAGGGLTKYNSAHSSSRVP 150

Query: 70  PPRARRTEPAVPPSCGSGPG-AAGALRMGLGRTQRAARVAVSRALAGTVAAAAG---LGA 125
            PR          SCG GPG  + A R GLG   R+AR    R    T     G    GA
Sbjct: 151 RPRLPSQRRGA--SCGLGPGPESRAARQGLG--GRSARARTRRGPHRTRRPEPGPHHTGA 206

Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEPP 176
           R+A    L G  G  R AGT  A  RG    L   S          G+ PP
Sbjct: 207 RQAG--PLPGTRGRTRAAGTGSA-ARGPARHLRGGSVAAAAAARCLGLSPP 254



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 47/167 (28%), Positives = 61/167 (36%), Gaps = 22/167 (13%)

Query: 21  LPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH---------ASTSSRSPPP 71
           L PTP+     + C PSP   A S    P + + PFLP S          +S  SR P P
Sbjct: 21  LHPTPSEA---LSCWPSPPGEAYSLPELPFKKSKPFLPQSKQKADTETIGSSGGSRGPSP 77

Query: 72  RARRTEPAVPPSCGSGPGAAGALRMGLGRTQR------AARVAVSRALAGTVAAAAGLGA 125
               T P   P    G   A + R+ L           A R +     AG   + AG G 
Sbjct: 78  AHPWTTPQPGPPHQPGFNPASSPRLPLPADSEPDAYTSAPRGSGPTYCAGAGNSRAGGGL 137

Query: 126 RRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKG 172
            +    H   ++   R+   P  R RG  C LG     R   +G  G
Sbjct: 138 TKYNSAHSSSRVPRPRL---PSQR-RGASCGLGPGPESRAARQGLGG 180


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 30/75 (40%), Positives = 36/75 (48%), Gaps = 6/75 (8%)

Query: 13  PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPS-RAAGPFLPPSHASTSSRSPP- 70
           P  PPPP +PP P    P    PP+P  P P  + +P+     P LPP+HA      PP 
Sbjct: 479 PPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHA-VPPHPPPG 537

Query: 71  ---PRARRTEPAVPP 82
              P A    PAVPP
Sbjct: 538 LGLPPASYPPPAVPP 552



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 8/73 (10%)

Query: 11  PSPILPPP-PDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSP 69
           P P +PPP P  PP P    P    PP P R  P+ +  P    G  LPP     +S  P
Sbjct: 495 PPPAIPPPTPGYPPPPPTYNP--NFPPPPPRLPPTHAVPPHPPPGLGLPP-----ASYPP 547

Query: 70  PPRARRTEPAVPP 82
           P      +P VPP
Sbjct: 548 PAVPPGGQPPVPP 560



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 10/94 (10%)

Query: 16  PPPPDLPPTPTRRAPLIGCPPSPARPAP-SASPSPSRAAGPF---------LPPSHASTS 65
           PPPP +P   T   PL    P P R  P +A+   +   GP          +PP      
Sbjct: 350 PPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAP 409

Query: 66  SRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLG 99
              PPP   R  P  P S  +G     +   G G
Sbjct: 410 VHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEG 443



 Score = 26.9 bits (58), Expect = 9.4
 Identities = 21/92 (22%), Positives = 30/92 (32%), Gaps = 24/92 (26%)

Query: 15  LPPPPDLPPTPT-----RRAPLIGCPPS-------------------PARPAPSASPSPS 50
           L  PP L PTP      +  P     PS                   P +P+P  S    
Sbjct: 273 LQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQ 332

Query: 51  RAAGPFLPPSHASTSSRSPPPRARRTEPAVPP 82
                 + P   + ++  PPP+  + E   PP
Sbjct: 333 VKRAVVVSPKEENKAAEPPPPKIPKIETTHPP 364


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 17/110 (15%)

Query: 2   AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSP--------------ARPAPSASP 47
           A A+A+   P P  PP     P   R +P  G P +P              +RP  ++ P
Sbjct: 766 APAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPLSASQP 825

Query: 48  S-PSRAAGPFLP--PSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGAL 94
           S P  A GP     P+ +ST    P P AR   P+      + PGAAG L
Sbjct: 826 SLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGAAGGL 875



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 40/142 (28%), Positives = 60/142 (42%), Gaps = 23/142 (16%)

Query: 3   GASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARP--APSASPSPSRAAGPFLPPS 60
           G + A A+P P   PPP  PP         G P SP  P  +P      +  AGP LP  
Sbjct: 764 GPAPAAASPGP---PPPASPP---------GAPASPRAPRTSPYGGLPAAPLAGPALPAR 811

Query: 61  HASTSSRSPPPRARRTEPAVP-----PSCGSGPGAAGALRMGLGRTQRAARVAVSRALAG 115
             S +SR        ++P++P     P+  + P ++   R+G     RAA  +  R  + 
Sbjct: 812 RLSRASRP----LSASQPSLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSA 867

Query: 116 TVAAAAGLGARRARRLHLRGQI 137
           +  AA GL  + + R  L   +
Sbjct: 868 SPGAAGGLDPQDSARSRLSSNL 889



 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 34/102 (33%), Positives = 38/102 (37%), Gaps = 20/102 (19%)

Query: 7   ARAAPSPILPPPP----DLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLP---- 58
           A  AP P  PPPP      PP P   AP  G  P+P +  P A   P  AA    P    
Sbjct: 16  ATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGRL 75

Query: 59  ------------PSHASTSSRSPPPRARRTEPAVPPSCGSGP 88
                       P  AST+  SP     R EP   P+   GP
Sbjct: 76  RSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGP 117



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 3/92 (3%)

Query: 9   AAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRS 68
           A P+P  PPPP  PP P ++ P    PP+P  P P  +P         LPP  A      
Sbjct: 16  ATPAPGPPPPP--PPAPPQQQPPPPPPPAPP-PGPGPAPPQHPPRAEALPPEAADEGGPR 72

Query: 69  PPPRARRTEPAVPPSCGSGPGAAGALRMGLGR 100
              R+R +    P + G+   A G+     GR
Sbjct: 73  GRLRSRDSSCGRPGTPGAASTAKGSPNGECGR 104



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 31/95 (32%), Positives = 35/95 (36%), Gaps = 22/95 (23%)

Query: 2  AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPF-LPPS 60
          A     R   SP   P P  PP P         PP+P +  P   P P+   GP   PP 
Sbjct: 3  ARGGGGRPGESPGATPAPGPPPPP---------PPAPPQQQPPPPPPPAPPPGPGPAPPQ 53

Query: 61 HASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALR 95
          H        PPRA     A+PP      G  G LR
Sbjct: 54 H--------PPRAE----ALPPEAADEGGPRGRLR 76



 Score = 34.7 bits (78), Expect = 0.045
 Identities = 42/166 (25%), Positives = 60/166 (36%), Gaps = 23/166 (13%)

Query: 17  PPPDLPPTPT------RRAPLIGCPPSPARP--APSASPSPSRAAGPFLPPSHASTSSRS 68
           PPP  PP  T      ++A  +   P  ARP   P A  SP     P   P+ A+ S   
Sbjct: 715 PPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGP 774

Query: 69  PPP----------RARRTEP--AVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGT 116
           PPP          RA RT P   +P +  +GP           R   A++ ++     G 
Sbjct: 775 PPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPLSASQPSLPHGAPGP 834

Query: 117 VAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSP 162
            A+     +   R   L      R  A +P+ R      + G + P
Sbjct: 835 AASTRPASSSTPR---LGPTPAARAAAPSPDRRDSASPGAAGGLDP 877


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 53/179 (29%), Positives = 73/179 (40%), Gaps = 17/179 (9%)

Query: 4   ASAARAAPSPILPPPPDLPPTPTRR---APL----IGCPPSPARPAPSASPSPSRAAGPF 56
           A A+   P P+L P P   P P      AP+    +   P+PA PAP+ +P+P  A  P 
Sbjct: 132 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAPVAAPAPA 190

Query: 57  LPPSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGT 116
             P+ A   + +P P A   E A     G+  G  G   +     Q  + ++  R  AGT
Sbjct: 191 PAPAPAPAPAPAPAPDAAPQESA---EQGANQGQRGQEPLA---DQLHSGIS-GRPAAGT 243

Query: 117 VAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEP 175
            AA+A   A +     L      +R    PE +  GD       SP   PG GS    P
Sbjct: 244 AAASANGAAIKKLSGPLISDFFAKRKRSAPE-KSSGD-VPAPCPSPSAAPGVGSVEQTP 300


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 53/179 (29%), Positives = 73/179 (40%), Gaps = 17/179 (9%)

Query: 4   ASAARAAPSPILPPPPDLPPTPTRR---APL----IGCPPSPARPAPSASPSPSRAAGPF 56
           A A+   P P+L P P   P P      AP+    +   P+PA PAP+ +P+P  A  P 
Sbjct: 132 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAPVAAPAPA 190

Query: 57  LPPSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGT 116
             P+ A   + +P P A   E A     G+  G  G   +     Q  + ++  R  AGT
Sbjct: 191 PAPAPAPAPAPAPAPDAAPQESA---EQGANQGQRGQEPLA---DQLHSGIS-GRPAAGT 243

Query: 117 VAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEP 175
            AA+A   A +     L      +R    PE +  GD       SP   PG GS    P
Sbjct: 244 AAASANGAAIKKLSGPLISDFFAKRKRSAPE-KSSGD-VPAPCPSPSAAPGVGSVEQTP 300


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 53/179 (29%), Positives = 73/179 (40%), Gaps = 17/179 (9%)

Query: 4   ASAARAAPSPILPPPPDLPPTPTRR---APL----IGCPPSPARPAPSASPSPSRAAGPF 56
           A A+   P P+L P P   P P      AP+    +   P+PA PAP+ +P+P  A  P 
Sbjct: 143 APASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPA-PAPAPAPAPVAAPAPA 201

Query: 57  LPPSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGT 116
             P+ A   + +P P A   E A     G+  G  G   +     Q  + ++  R  AGT
Sbjct: 202 PAPAPAPAPAPAPAPDAAPQESA---EQGANQGQRGQEPLA---DQLHSGIS-GRPAAGT 254

Query: 117 VAAAAGLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSPDRTPGKGSKGMEP 175
            AA+A   A +     L      +R    PE +  GD       SP   PG GS    P
Sbjct: 255 AAASANGAAIKKLSGPLISDFFAKRKRSAPE-KSSGD-VPAPCPSPSAAPGVGSVEQTP 311


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 10/81 (12%)

Query: 11  PSPILPPPPD-LPPTPTRRAPLIGC---PPSPARPAPSASPSPSRAAGPFLPPSHASTSS 66
           P   + PPPD +PP P   A + G    PP P  PAP+ +P P  A  P       + + 
Sbjct: 572 PPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPP------PAVAK 625

Query: 67  RSPPPRARRTEPAVPPSCGSG 87
           R P P  R+  P  P   G G
Sbjct: 626 RPPVPPKRQENPGHPGGAGGG 646



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 35/105 (33%), Positives = 40/105 (38%), Gaps = 20/105 (19%)

Query: 3   GASAARAAPSPILPPPP-----DLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFL 57
           G     A P   LPPPP     D P  P      +  PP    P P   PS +  AG  L
Sbjct: 542 GGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPP---PSYAGIAGSEL 598

Query: 58  P----------PSHASTSSRSPPPRARRTEPAVPPSCGSGPGAAG 92
           P          P+    S+R PP  A+R  P VPP     PG  G
Sbjct: 599 PPPPPPPPAPAPAPVPDSARPPPAVAKR--PPVPPKRQENPGHPG 641


>gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]
          Length = 1159

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 40/126 (31%), Positives = 48/126 (38%), Gaps = 28/126 (22%)

Query: 23  PTPTRRAPLIGCPPSPARP----------------APSASPSPSRAAG-------PFLPP 59
           P PT RAP  G PP P  P                A   SP P R          P  PP
Sbjct: 13  PGPTARAPSPGAPPPPRSPRSRPLLLLLLLLGACGAAGRSPEPGRLGPHAQLTRVPRSPP 72

Query: 60  SHASTSSRSPPPRARRTEPAVP---PSCGSGPGAAGALRMGLGRTQRAARVA--VSRALA 114
           +  +        +AR TEP  P   P    GPG  GA   G  R +RAA +A   SRA  
Sbjct: 73  AGRAEPGGGEDRQARGTEPGAPGPSPGPAPGPGEDGAPAAGYRRWERAAPLAGVASRAQV 132

Query: 115 GTVAAA 120
             ++ +
Sbjct: 133 SLISTS 138


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
           [Homo sapiens]
          Length = 1336

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 43/128 (33%), Positives = 51/128 (39%), Gaps = 33/128 (25%)

Query: 1   MAGASAARAAPSPILPPPPDL-PPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPP 59
           M    +A AAP P  PPPP                 PSPA PAP  +P P+    PF+P 
Sbjct: 893 MYSCCSAEAAPPPAKPPPPPQP-------------LPSPAYPAPRPAPGPA----PFVPR 935

Query: 60  SHASTSSRSPPPRARRTEPAVPPSCGS---------GPGAAGALRMGLGRTQRAARVAVS 110
             AS        R RRT+ A PP             GP     L +GLG  + A R A  
Sbjct: 936 ERASVD------RWRRTKGAGPPGGAGLADGFHRYYGPIEPQGLGLGLGEARAAPRGAAG 989

Query: 111 RALAGTVA 118
           R L+   A
Sbjct: 990 RPLSPPAA 997



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 37/109 (33%), Positives = 44/109 (40%), Gaps = 23/109 (21%)

Query: 3    GASAARAAPS-----PILPP---PPDLPPTP---------TRRAPLIGCPPSPARPAPSA 45
            G   ARAAP      P+ PP   PP  PP               P    P  P+ PAP A
Sbjct: 976  GLGEARAAPRGAAGRPLSPPAAQPPQKPPPSYFAIVRDKEPAEPPAGAFPGFPSPPAPPA 1035

Query: 46   SPSPSRAAGPFLPPSHASTSSRSPPPRAR--RTEPAVPPSCGSGPGAAG 92
            + +   A GP  P    +    SPP  AR  R++P   P  G G G AG
Sbjct: 1036 AAAT--AVGP--PLCRLAFEDESPPAPARWPRSDPESQPLLGPGAGGAG 1080



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 45/137 (32%), Positives = 56/137 (40%), Gaps = 34/137 (24%)

Query: 16   PPPPDLPPTPTRRAPLIGCPPS-PARPAPS----ASPSP-----SRAAGPF-LPPSHAST 64
            PPP    P P RRA   GCP S P RP  S    A+ +P      RAAG + LPP     
Sbjct: 1211 PPPWAAGPLPRRRARC-GCPRSHPHRPRASHRTPAAAAPHHHRHRRAAGGWDLPP----- 1264

Query: 65   SSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAAGLG 124
                P P +R  E        S P AA A R+  G ++ A R   +      +  A    
Sbjct: 1265 ----PAPTSRSLE-----DLSSCPRAAPARRL-TGPSRHARRCPHAAHWGPPLPTA---- 1310

Query: 125  ARRARRLHLRGQIGVRR 141
               + R H  G +G RR
Sbjct: 1311 ---SHRRHRGGDLGTRR 1324


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 33/83 (39%), Positives = 38/83 (45%), Gaps = 15/83 (18%)

Query: 5   SAARAAPSPI-----LPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPP 59
           +AA AAPS +     LPPPP  PP P    P    PP P  P P   P P     P  PP
Sbjct: 666 AAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPP---PPQPGFPMPPPLPPPP----PPPPP 718

Query: 60  SHASTSSRSPPPRARRTEPAVPP 82
           +H + +   PP  A    P VPP
Sbjct: 719 AHPAVTVPPPPLPA---PPGVPP 738



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 20/47 (42%), Positives = 22/47 (46%), Gaps = 6/47 (12%)

Query: 13  PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPP 59
           P+ PP P  PP P    P +  PP P  PAP   P P     P LPP
Sbjct: 704 PMPPPLPPPPPPPPPAHPAVTVPPPPL-PAPPGVPPP-----PILPP 744



 Score = 33.9 bits (76), Expect = 0.077
 Identities = 26/74 (35%), Positives = 29/74 (39%), Gaps = 18/74 (24%)

Query: 13   PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPPR 72
            P++ P P  PP P         PP P RP PS  P P          + AS  S  P P 
Sbjct: 1271 PMMLPLPLQPPLP---------PPRPPRP-PSPPPEPE--------TTDASHPSVPPEPL 1312

Query: 73   ARRTEPAVPPSCGS 86
            A    P  P  CGS
Sbjct: 1313 AEDHPPHTPGLCGS 1326



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 25/81 (30%), Positives = 36/81 (44%), Gaps = 8/81 (9%)

Query: 1    MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60
            ++G S+  +  SP +P  P   P P+      G P +P R   S +P+ S  +GP L P 
Sbjct: 1346 LSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDF-SFTPTFSEPSGPLLLPV 1404

Query: 61   HASTSSRSPPPRARRTEPAVP 81
                    P P  RR E + P
Sbjct: 1405 -------CPLPTGRRDERSGP 1418



 Score = 32.3 bits (72), Expect = 0.22
 Identities = 24/82 (29%), Positives = 30/82 (36%), Gaps = 6/82 (7%)

Query: 11  PSP-ILPPPPDLPPTPTRRAPLIGCPPSPARP--APSASPSPSRAAGPFLPPSHASTSSR 67
           P P ++ P       P+  AP +  PP P  P   P   P P +   P  PP        
Sbjct: 657 PKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPP---LPPPP 713

Query: 68  SPPPRARRTEPAVPPSCGSGPG 89
            PPP A       PP   + PG
Sbjct: 714 PPPPPAHPAVTVPPPPLPAPPG 735



 Score = 31.6 bits (70), Expect = 0.38
 Identities = 25/96 (26%), Positives = 38/96 (39%), Gaps = 13/96 (13%)

Query: 16   PPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPP---- 71
            P PP + P P +  P +  P  P  P+P   P  + A+ P +PP   +       P    
Sbjct: 1268 PEPPMMLPLPLQ--PPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCG 1325

Query: 72   -----RARRTEPAVPPSCGSGPGAAGALRMGLGRTQ 102
                 ++  T PA P   G  P + G+  + L   Q
Sbjct: 1326 SLAKSQSTETVPATPG--GEPPLSGGSSGLSLSSPQ 1359



 Score = 30.8 bits (68), Expect = 0.65
 Identities = 28/91 (30%), Positives = 31/91 (34%), Gaps = 7/91 (7%)

Query: 11   PSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPP 70
            P P+  P P   P   R       P  P  PAP AS  P     P  P        RSPP
Sbjct: 1432 PLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRP-------RRSPP 1484

Query: 71   PRARRTEPAVPPSCGSGPGAAGALRMGLGRT 101
                   P V P  G+  G    L  G  +T
Sbjct: 1485 SMLSLDGPLVRPPAGAALGRELLLLPGQPQT 1515



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 15/88 (17%)

Query: 5    SAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGP--------- 55
            +A   AP P LPP P  PP P    P +     P +   +  PS +   GP         
Sbjct: 1533 NAGIPAPPPPLPPQPPPPPPP----PPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEE 1588

Query: 56   FLPPSHASTSSRSPPPRARRTEPAVPPS 83
            ++  + +    R PP   +R E  VPP+
Sbjct: 1589 YMELAKSRGPWRRPP--KKRHEDLVPPA 1614



 Score = 28.5 bits (62), Expect = 3.2
 Identities = 20/56 (35%), Positives = 22/56 (39%), Gaps = 3/56 (5%)

Query: 12  SPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSR 67
           +P  PPPPD         P  G  P P   +P      S  AGP  P  H S  SR
Sbjct: 450 TPPGPPPPDTNSMELGGRPTFGWSPEPC-DSPGTPTLESSPAGPEKP--HDSLDSR 502



 Score = 27.3 bits (59), Expect = 7.2
 Identities = 18/64 (28%), Positives = 21/64 (32%), Gaps = 9/64 (14%)

Query: 16  PPPPDLPPTPTRRAPLIGCPPSPARP---------APSASPSPSRAAGPFLPPSHASTSS 66
           P PP LPP         G PP P  P          P+   SP     P  P   +S + 
Sbjct: 432 PAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAG 491

Query: 67  RSPP 70
              P
Sbjct: 492 PEKP 495



 Score = 27.3 bits (59), Expect = 7.2
 Identities = 15/33 (45%), Positives = 16/33 (48%), Gaps = 1/33 (3%)

Query: 4   ASAARAAPSPILPPPPDLPPTPTRRAPLIGCPP 36
           A  A   P P LP PP +PP P    PL   PP
Sbjct: 719 AHPAVTVPPPPLPAPPGVPPPPI-LPPLPPFPP 750


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 33/96 (34%), Positives = 34/96 (35%), Gaps = 9/96 (9%)

Query: 11  PSPILPPPPDLP-------PTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHAS 63
           P   +PPPP LP       P P       G P  P  P P   P PS A  P  PP    
Sbjct: 648 PPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPP--PPPPPP 705

Query: 64  TSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLG 99
               SP P      P  PP  G  P     L  GLG
Sbjct: 706 PLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLG 741



 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 30/87 (34%), Positives = 34/87 (39%), Gaps = 14/87 (16%)

Query: 13  PILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSHASTSSRSPPPR 72
           P LPPPP  PP P       G PP P  P    SP+P    GP  PP+        PPP 
Sbjct: 678 PPLPPPPP-PPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGP--PPAPPPPGLAPPPPP 734

Query: 73  AR-----------RTEPAVPPSCGSGP 88
                          +PA+ PSC   P
Sbjct: 735 GLFFGLGSSSSQCPRKPAIEPSCPMKP 761


>gi|210031233 PR domain containing 6 [Homo sapiens]
          Length = 595

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 47/161 (29%), Positives = 61/161 (37%), Gaps = 34/161 (21%)

Query: 2   AGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPSH 61
           +GA+   +AP P+ PPPP  PP P R  P    PP   RP P                  
Sbjct: 38  SGAAGLLSAPQPLQPPPP--PPPPERAEP----PPDSLRPRP------------------ 73

Query: 62  ASTSSRSPPPRARRTEPAVPPSCGSGPGAAGALRMGLGRTQRAARVAVSRALAGTVAAAA 121
           AS SS S  P +  T  +   SC +   AA A   GL      +++ V   LA    AA 
Sbjct: 74  ASLSSASSTPASSSTSASSASSCAA--AAAAAALAGLSALP-VSQLPVFAPLAAAAVAAE 130

Query: 122 GLGARRARRLHLRGQIGVRRVAGTPEARGRGDGCSLGRVSP 162
            L  +          +G     G  +  G G G   GR +P
Sbjct: 131 PLPPKEL-------CLGATSGPGPVKCGGGGGGGGEGRGAP 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,709,082
Number of Sequences: 37866
Number of extensions: 781949
Number of successful extensions: 22602
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1046
Number of HSP's successfully gapped in prelim test: 1804
Number of HSP's that attempted gapping in prelim test: 7409
Number of HSP's gapped (non-prelim): 10499
length of query: 179
length of database: 18,247,518
effective HSP length: 96
effective length of query: 83
effective length of database: 14,612,382
effective search space: 1212827706
effective search space used: 1212827706
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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