Search of human proteins with 239582741

Search of human proteins with 239582741

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239582741 FERM and PDZ domain containing 1 [Homo sapiens]
         (1578 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239582741 FERM and PDZ domain containing 1 [Homo sapiens]         3159   0.0  
gi|211971072 FERM and PDZ domain containing 4 [Homo sapiens]          457   e-128
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa...   347   5e-95
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa...   347   5e-95
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s...   201   6e-51
gi|27886590 PTK2B protein tyrosine kinase 2 beta isoform a [Homo...    68   6e-11
gi|27886588 PTK2B protein tyrosine kinase 2 beta isoform b [Homo...    68   6e-11
gi|27886586 PTK2B protein tyrosine kinase 2 beta isoform a [Homo...    68   6e-11
gi|27886584 PTK2B protein tyrosine kinase 2 beta isoform a [Homo...    68   6e-11
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    47   1e-04
gi|122937249 glutamate receptor interacting protein 2 [Homo sapi...    46   2e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        44   0.002
gi|55953110 retinoblastoma protein-binding zinc finger protein i...    44   0.002
gi|20336260 retinoblastoma protein-binding zinc finger protein i...    44   0.002
gi|20336258 retinoblastoma protein-binding zinc finger protein i...    44   0.002
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int...    43   0.003
gi|32479521 dishevelled 1 [Homo sapiens]                               43   0.003
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]         43   0.003
gi|4759306 lin-7 homolog A [Homo sapiens]                              42   0.005
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]                42   0.006
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]           41   0.008
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]           41   0.008
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    41   0.010
gi|21071018 epidermal growth factor receptor pathway substrate 8...    41   0.010
gi|239756829 PREDICTED: zinc finger protein 385C [Homo sapiens]        40   0.018
gi|239751322 PREDICTED: zinc finger protein 385C [Homo sapiens]        40   0.018
gi|239745821 PREDICTED: zinc finger protein 385C [Homo sapiens]        40   0.018
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    40   0.018
gi|11545920 lin-7 homolog B [Homo sapiens]                             40   0.018
gi|193083191 synaptopodin 2 isoform c [Homo sapiens]                   40   0.023

>gi|239582741 FERM and PDZ domain containing 1 [Homo sapiens]
          Length = 1578

 Score = 3159 bits (8191), Expect = 0.0
 Identities = 1578/1578 (100%), Positives = 1578/1578 (100%)

Query: 1    MEELETSLFQTRKAHRIEQMVARWLRRSRDSSARAKVAAADGPARNPTQTLIPVRHTVKI 60
            MEELETSLFQTRKAHRIEQMVARWLRRSRDSSARAKVAAADGPARNPTQTLIPVRHTVKI
Sbjct: 1    MEELETSLFQTRKAHRIEQMVARWLRRSRDSSARAKVAAADGPARNPTQTLIPVRHTVKI 60

Query: 61   DKDTLLQDYGFHISESLPLTVVAVTAGGSAHGKLFPGDQILQMNNEPAEDLSWERAVDIL 120
            DKDTLLQDYGFHISESLPLTVVAVTAGGSAHGKLFPGDQILQMNNEPAEDLSWERAVDIL
Sbjct: 61   DKDTLLQDYGFHISESLPLTVVAVTAGGSAHGKLFPGDQILQMNNEPAEDLSWERAVDIL 120

Query: 121  REAEDSLSITVVRCTSGVPKSSFLTEEKRARLKTNPVKVHFAEEVLISGHSQGNSLLCMP 180
            REAEDSLSITVVRCTSGVPKSSFLTEEKRARLKTNPVKVHFAEEVLISGHSQGNSLLCMP
Sbjct: 121  REAEDSLSITVVRCTSGVPKSSFLTEEKRARLKTNPVKVHFAEEVLISGHSQGNSLLCMP 180

Query: 181  NVLKLYLENGQTKAFKFEANTTVKDIILTVKEKLSIRSIEYFALALEEQYSISRLHLLHE 240
            NVLKLYLENGQTKAFKFEANTTVKDIILTVKEKLSIRSIEYFALALEEQYSISRLHLLHE
Sbjct: 181  NVLKLYLENGQTKAFKFEANTTVKDIILTVKEKLSIRSIEYFALALEEQYSISRLHLLHE 240

Query: 241  EELIQQVVEREESHDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEM 300
            EELIQQVVEREESHDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEM
Sbjct: 241  EELIQQVVEREESHDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEM 300

Query: 301  KCSSALRLAALHIQERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISF 360
            KCSSALRLAALHIQERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISF
Sbjct: 301  KCSSALRLAALHIQERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISF 360

Query: 361  HMKRNQNLLEPRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGA 420
            HMKRNQNLLEPRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGA
Sbjct: 361  HMKRNQNLLEPRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGA 420

Query: 421  KYGISQVINSKLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESNSAKD 480
            KYGISQVINSKLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESNSAKD
Sbjct: 421  KYGISQVINSKLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESNSAKD 480

Query: 481  LACLIAGYYRLLVDPVTSIFLWPGNKQQAHRVSAEEGYESRACSDSEESSEVDCVLEPLS 540
            LACLIAGYYRLLVDPVTSIFLWPGNKQQAHRVSAEEGYESRACSDSEESSEVDCVLEPLS
Sbjct: 481  LACLIAGYYRLLVDPVTSIFLWPGNKQQAHRVSAEEGYESRACSDSEESSEVDCVLEPLS 540

Query: 541  DRRLVKLAPCRSLIKEEQPPGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGY 600
            DRRLVKLAPCRSLIKEEQPPGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGY
Sbjct: 541  DRRLVKLAPCRSLIKEEQPPGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGY 600

Query: 601  RTSGSSESMDALEEDDLDTCSSSRSTFFHFGSPGLAESIDSDSQEERSGIETSGFLCLLD 660
            RTSGSSESMDALEEDDLDTCSSSRSTFFHFGSPGLAESIDSDSQEERSGIETSGFLCLLD
Sbjct: 601  RTSGSSESMDALEEDDLDTCSSSRSTFFHFGSPGLAESIDSDSQEERSGIETSGFLCLLD 660

Query: 661  LAQRANPQCQKTEFSESAALETFGWAPELSTVRLDPRLYEGSHADYYSLCSSVSPASYLS 720
            LAQRANPQCQKTEFSESAALETFGWAPELSTVRLDPRLYEGSHADYYSLCSSVSPASYLS
Sbjct: 661  LAQRANPQCQKTEFSESAALETFGWAPELSTVRLDPRLYEGSHADYYSLCSSVSPASYLS 720

Query: 721  DSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSSDEEYYDAADKLTP 780
            DSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSSDEEYYDAADKLTP
Sbjct: 721  DSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSSDEEYYDAADKLTP 780

Query: 781  PGPPSGPRDVSTAEPSATSLQNKASTSSPENSLPCGPDGRQPSRRGGVKKYAKTLRKRRS 840
            PGPPSGPRDVSTAEPSATSLQNKASTSSPENSLPCGPDGRQPSRRGGVKKYAKTLRKRRS
Sbjct: 781  PGPPSGPRDVSTAEPSATSLQNKASTSSPENSLPCGPDGRQPSRRGGVKKYAKTLRKRRS 840

Query: 841  FLQTDYTSQVSFPLVPSASLESVDDVCYYDREPYLALGAPSPTVSSLQDMQGEPGLLETK 900
            FLQTDYTSQVSFPLVPSASLESVDDVCYYDREPYLALGAPSPTVSSLQDMQGEPGLLETK
Sbjct: 841  FLQTDYTSQVSFPLVPSASLESVDDVCYYDREPYLALGAPSPTVSSLQDMQGEPGLLETK 900

Query: 901  ALGLLAPLRETKSTNPASRVMEMEPETMETKSVIDSRVSSISAIRFRIDPNNKENSGVVP 960
            ALGLLAPLRETKSTNPASRVMEMEPETMETKSVIDSRVSSISAIRFRIDPNNKENSGVVP
Sbjct: 901  ALGLLAPLRETKSTNPASRVMEMEPETMETKSVIDSRVSSISAIRFRIDPNNKENSGVVP 960

Query: 961  AASSSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDP 1020
            AASSSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDP
Sbjct: 961  AASSSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDP 1020

Query: 1021 NPDRACLASNPGLNNVSQGDTLELQLEPHVQLEMGLESFCTNHIQETAPKYTEPLLSPRD 1080
            NPDRACLASNPGLNNVSQGDTLELQLEPHVQLEMGLESFCTNHIQETAPKYTEPLLSPRD
Sbjct: 1021 NPDRACLASNPGLNNVSQGDTLELQLEPHVQLEMGLESFCTNHIQETAPKYTEPLLSPRD 1080

Query: 1081 EPRSDECGINPGEKIASIPTKEEPQGQLSLERDREVTNKNGTNVFQEESRKDSGDSPGDV 1140
            EPRSDECGINPGEKIASIPTKEEPQGQLSLERDREVTNKNGTNVFQEESRKDSGDSPGDV
Sbjct: 1081 EPRSDECGINPGEKIASIPTKEEPQGQLSLERDREVTNKNGTNVFQEESRKDSGDSPGDV 1140

Query: 1141 SNNVSQTLDISSPAGKIVTSLSLDAPVTGTEQIPPHPPRDPQGQSREPPGQGCQAQEQKL 1200
            SNNVSQTLDISSPAGKIVTSLSLDAPVTGTEQIPPHPPRDPQGQSREPPGQGCQAQEQKL
Sbjct: 1141 SNNVSQTLDISSPAGKIVTSLSLDAPVTGTEQIPPHPPRDPQGQSREPPGQGCQAQEQKL 1200

Query: 1201 FVELDLDPDFFLGKQTVSPAVPPEGIKAEAPNHVTGQDIAPRDSPEWVCFNPEPSLPEPL 1260
            FVELDLDPDFFLGKQTVSPAVPPEGIKAEAPNHVTGQDIAPRDSPEWVCFNPEPSLPEPL
Sbjct: 1201 FVELDLDPDFFLGKQTVSPAVPPEGIKAEAPNHVTGQDIAPRDSPEWVCFNPEPSLPEPL 1260

Query: 1261 PCPQEDPHLETSNHCLLSEGKSDSSSICLSAEKSFLCFAPESHPEVSASLRVATSLGFAG 1320
            PCPQEDPHLETSNHCLLSEGKSDSSSICLSAEKSFLCFAPESHPEVSASLRVATSLGFAG
Sbjct: 1261 PCPQEDPHLETSNHCLLSEGKSDSSSICLSAEKSFLCFAPESHPEVSASLRVATSLGFAG 1320

Query: 1321 MNEMVAPRIGMDQCSCQFSYATCFRGPQPETEEEDRDLEAHPMAPLTSPPSAGSPVVLPW 1380
            MNEMVAPRIGMDQCSCQFSYATCFRGPQPETEEEDRDLEAHPMAPLTSPPSAGSPVVLPW
Sbjct: 1321 MNEMVAPRIGMDQCSCQFSYATCFRGPQPETEEEDRDLEAHPMAPLTSPPSAGSPVVLPW 1380

Query: 1381 RPARAHSCTTAPLSRKSHIWPEYCSRALRQLKATPASTPEGFIQLMESLLELQDILETSW 1440
            RPARAHSCTTAPLSRKSHIWPEYCSRALRQLKATPASTPEGFIQLMESLLELQDILETSW
Sbjct: 1381 RPARAHSCTTAPLSRKSHIWPEYCSRALRQLKATPASTPEGFIQLMESLLELQDILETSW 1440

Query: 1441 GVGNKHPPEKCTWHFTESRSRLCMGSQKLLSSCRHVIRMDQSPEEMQGAVRDTFQHLVQL 1500
            GVGNKHPPEKCTWHFTESRSRLCMGSQKLLSSCRHVIRMDQSPEEMQGAVRDTFQHLVQL
Sbjct: 1441 GVGNKHPPEKCTWHFTESRSRLCMGSQKLLSSCRHVIRMDQSPEEMQGAVRDTFQHLVQL 1500

Query: 1501 AGLCFQFTDCSRCSARHREAAGNLRDVVYTYHQFIEAAKSTCERGYHDLSVKLLARQCTA 1560
            AGLCFQFTDCSRCSARHREAAGNLRDVVYTYHQFIEAAKSTCERGYHDLSVKLLARQCTA
Sbjct: 1501 AGLCFQFTDCSRCSARHREAAGNLRDVVYTYHQFIEAAKSTCERGYHDLSVKLLARQCTA 1560

Query: 1561 LTAAVFCLTQKFRASTAL 1578
            LTAAVFCLTQKFRASTAL
Sbjct: 1561 LTAAVFCLTQKFRASTAL 1578


>gi|211971072 FERM and PDZ domain containing 4 [Homo sapiens]
          Length = 1322

 Score =  457 bits (1176), Expect = e-128
 Identities = 238/482 (49%), Positives = 343/482 (71%), Gaps = 10/482 (2%)

Query: 41  DGPARNPTQTLIPVRHTVKIDKDTLLQDYGFHISESLPLTVVAVTAGGSAHGKLFPGDQI 100
           D P     Q + P    V++ +D +L  +GF      P+ V +VT GG + GKL PGDQI
Sbjct: 62  DDPRLESCQIIPPAPRKVEMRRDPVL-GFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQI 120

Query: 101 LQMNNEPAEDLSWERAVDILREAEDSLSITVVRCTSGVPKSSFLTEEKRARLKTNPVKVH 160
           + +N+EP      ER +D++R  ++S+ +TV++     PKS+F++  K+ARLK+NPVKV 
Sbjct: 121 VMINDEPVSAAPRERVIDLVRSCKESILLTVIQPYPS-PKSAFISAAKKARLKSNPVKVR 179

Query: 161 FAEEVLISGHS----QGNSLLCMPNVLKLYLENGQTKAFKFEANTTVKDIILTVKEKLSI 216
           F+EEV+I+G      + NSLL MPNVLK+YLENGQTK+F+F+ +T++KD+ILT++EKLSI
Sbjct: 180 FSEEVIINGQVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSI 239

Query: 217 RSIEYFALALEEQY--SISRLHLLHEEELIQQVVEREESHDYRCLFRVCFVPKDPLDLLK 274
           + IE+F+L LE++   + ++L LLHE+E + QV +R  SH  RCLFR+ FVPKDP+DLL+
Sbjct: 240 KGIEHFSLMLEQRTEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLR 299

Query: 275 EDPVAFEYLYLQSCSDVLQERFAVEMKCSSALRLAALHIQERIYACAQPQKISLKYIEKD 334
            DPVAFEYLY+QSC+DV+QERF  E+K   ALRLAAL +        Q QKISLKYIEK+
Sbjct: 300 RDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQTQKISLKYIEKE 359

Query: 335 WGIENFISPTLLRNMKGKDIKKAISFHMKRNQNLLEPRQKQLISAAQLRLNYLQILGELK 394
           WG+E F+   +L++MK K+IKKA+S  +K NQNL+ P +K  +SA Q +++YL+ L +L+
Sbjct: 360 WGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPGKK--LSALQAKVHYLKFLSDLR 417

Query: 395 TYGGRIFNATLMLQDRESYIALLVGAKYGISQVINSKLNIMSTLAEFANISRVELTEESE 454
            YGGR+F ATL+  ++ S + LLVG +YGIS VIN+K N+++ LA+F++++R+E+  E E
Sbjct: 418 LYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVALLADFSHVNRIEMFSEEE 477

Query: 455 KVSVVKVYLQDVKVLTLLLESNSAKDLACLIAGYYRLLVDPVTSIFLWPGNKQQAHRVSA 514
            +  V++++ DVK +TLL+ES+ A +LACL AGYYRLLVD   SIF     K  A + + 
Sbjct: 478 SLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNTATQETG 537

Query: 515 EE 516
            E
Sbjct: 538 PE 539



 Score = 31.6 bits (70), Expect = 6.3
 Identities = 14/15 (93%), Positives = 14/15 (93%)

Query: 921  MEMEPETMETKSVID 935
            MEMEPETMETKSV D
Sbjct: 995  MEMEPETMETKSVTD 1009


>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
           sapiens]
          Length = 1810

 Score =  347 bits (890), Expect = 5e-95
 Identities = 191/446 (42%), Positives = 293/446 (65%), Gaps = 14/446 (3%)

Query: 69  YGFHISESLPLTVVAVTAGGSAHGKLFPGDQILQMNNEPAEDLSWERAVDILREAEDSLS 128
           +GF      P+ V +V  GG +  KL  GDQI+ +N E   +   ER ++++R A++ + 
Sbjct: 65  FGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAKEFIV 124

Query: 129 ITVVRCTSGVPKSSFLTEEKRARLKTNPVKVHFAEEVLISGHS----QGNSLLCMPNVLK 184
           +TV+  T   PKS+F++  K+A+L++NPVKV F+E+V +        +  +LL +PNVLK
Sbjct: 125 LTVLH-THQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPNVLK 183

Query: 185 LYLENGQTKAFKFEANTTVKDIILTVKEKLSIRSIEYFALALE----EQYSISRLHLLHE 240
           ++LENGQ K+F F+  TTVKD++LT++++LS+R IE+FAL LE    EQ    +  LL +
Sbjct: 184 VFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNH--KFLLLQD 241

Query: 241 EELIQQVVEREESHDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEM 300
           ++ +  VV+R   H  +CLFR+ F PKDP++LL+ DP AFEYLY+QS +DV++ERF ++ 
Sbjct: 242 KQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDP 301

Query: 301 KCSSALRLAALHIQERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISF 360
           K    L LAALHI   + A    QKISLK +EK+WG+E F+ P+LL+ +K K+++K++S 
Sbjct: 302 KPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQ 361

Query: 361 HMKRNQNLLEPRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGA 420
            +K +Q    P      SA Q +L YL+IL EL T+ G +FN T+ L +++S   LLVG 
Sbjct: 362 QLKAHQT--HPSCGTKGSAIQAKLQYLRILNELPTFTGVLFN-TVGLDEKQSATTLLVGP 418

Query: 421 KYGISQVINSKLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESNSAKD 480
           ++GIS VI+ K N+ + L+EF+ IS+++L  E++ V+ V+  + D K L LL+E   A +
Sbjct: 419 RHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATN 478

Query: 481 LACLIAGYYRLLVDPVTSIFLWPGNK 506
            ACLIAGY RLL+D    +F  P ++
Sbjct: 479 FACLIAGYCRLLLDSRKMVFSRPASQ 504



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 34/137 (24%), Positives = 58/137 (42%)

Query: 1408 LRQLKATPASTPEGFIQLMESLLELQDILETSWGVGNKHPPEKCTWHFTESRSRLCMGSQ 1467
            +  L+A     P+GF+       EL  +L           P+      +E +  L +  +
Sbjct: 1610 INALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFK 1669

Query: 1468 KLLSSCRHVIRMDQSPEEMQGAVRDTFQHLVQLAGLCFQFTDCSRCSARHREAAGNLRDV 1527
            +L +SCR V  +D+SP  M  A+  +FQ L  L     +     R  A+ +E    + +V
Sbjct: 1670 ELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEV 1729

Query: 1528 VYTYHQFIEAAKSTCER 1544
            V  Y   + AA+ +  R
Sbjct: 1730 VRNYTFLLRAAEESTAR 1746


>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
           sapiens]
          Length = 1810

 Score =  347 bits (890), Expect = 5e-95
 Identities = 191/446 (42%), Positives = 293/446 (65%), Gaps = 14/446 (3%)

Query: 69  YGFHISESLPLTVVAVTAGGSAHGKLFPGDQILQMNNEPAEDLSWERAVDILREAEDSLS 128
           +GF      P+ V +V  GG +  KL  GDQI+ +N E   +   ER ++++R A++ + 
Sbjct: 65  FGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAKEFIV 124

Query: 129 ITVVRCTSGVPKSSFLTEEKRARLKTNPVKVHFAEEVLISGHS----QGNSLLCMPNVLK 184
           +TV+  T   PKS+F++  K+A+L++NPVKV F+E+V +        +  +LL +PNVLK
Sbjct: 125 LTVLH-THQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPNVLK 183

Query: 185 LYLENGQTKAFKFEANTTVKDIILTVKEKLSIRSIEYFALALE----EQYSISRLHLLHE 240
           ++LENGQ K+F F+  TTVKD++LT++++LS+R IE+FAL LE    EQ    +  LL +
Sbjct: 184 VFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNH--KFLLLQD 241

Query: 241 EELIQQVVEREESHDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEM 300
           ++ +  VV+R   H  +CLFR+ F PKDP++LL+ DP AFEYLY+QS +DV++ERF ++ 
Sbjct: 242 KQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDP 301

Query: 301 KCSSALRLAALHIQERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISF 360
           K    L LAALHI   + A    QKISLK +EK+WG+E F+ P+LL+ +K K+++K++S 
Sbjct: 302 KPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQ 361

Query: 361 HMKRNQNLLEPRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGA 420
            +K +Q    P      SA Q +L YL+IL EL T+ G +FN T+ L +++S   LLVG 
Sbjct: 362 QLKAHQT--HPSCGTKGSAIQAKLQYLRILNELPTFTGVLFN-TVGLDEKQSATTLLVGP 418

Query: 421 KYGISQVINSKLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESNSAKD 480
           ++GIS VI+ K N+ + L+EF+ IS+++L  E++ V+ V+  + D K L LL+E   A +
Sbjct: 419 RHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATN 478

Query: 481 LACLIAGYYRLLVDPVTSIFLWPGNK 506
            ACLIAGY RLL+D    +F  P ++
Sbjct: 479 FACLIAGYCRLLLDSRKMVFSRPASQ 504



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 34/137 (24%), Positives = 58/137 (42%)

Query: 1408 LRQLKATPASTPEGFIQLMESLLELQDILETSWGVGNKHPPEKCTWHFTESRSRLCMGSQ 1467
            +  L+A     P+GF+       EL  +L           P+      +E +  L +  +
Sbjct: 1610 INALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFK 1669

Query: 1468 KLLSSCRHVIRMDQSPEEMQGAVRDTFQHLVQLAGLCFQFTDCSRCSARHREAAGNLRDV 1527
            +L +SCR V  +D+SP  M  A+  +FQ L  L     +     R  A+ +E    + +V
Sbjct: 1670 ELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEV 1729

Query: 1528 VYTYHQFIEAAKSTCER 1544
            V  Y   + AA+ +  R
Sbjct: 1730 VRNYTFLLRAAEESTAR 1746


>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
           sapiens]
          Length = 1662

 Score =  201 bits (510), Expect = 6e-51
 Identities = 140/446 (31%), Positives = 222/446 (49%), Gaps = 68/446 (15%)

Query: 69  YGFHISESLPLTVVAVTAGGSAHGKLFPGDQILQMNNEPAEDLSWERAVDILREAEDSLS 128
           +GF      P+ V +V  GG +  KL  GDQI+ +N E   +   ER ++++R A++ + 
Sbjct: 32  FGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAKEFIV 91

Query: 129 ITVVRCTSGVPKSSFLTEEKRARLKTNPVKVHFAEEVLISGHS----QGNSLLCMPNVLK 184
           +TV+  T   PKS+F++  K+A+L++NPVKV F+E+V +        +  +LL +PNVLK
Sbjct: 92  LTVLH-THQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPNVLK 150

Query: 185 LYLENGQTKAFKFEANTTVKDIILTVKEKLSIRSIEYFALALE----EQYSISRLHLLHE 240
           ++LENGQ K+F F+  TTVKD++LT++++LS+R IE+FAL LE    EQ    +  LL +
Sbjct: 151 VFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQN--HKFLLLQD 208

Query: 241 EELIQQVVEREESHDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEM 300
           ++ +  VV+R   H  +CLFR+ F PKDP++LL+ DP AFEYLY+Q             +
Sbjct: 209 KQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQXXXXXXXXIKEKNL 268

Query: 301 KCSSALRLAALHIQERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISF 360
           + S + +L A              +  L+Y+     +  F    +L N  G D K++ + 
Sbjct: 269 RKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTG--VLFNTVGLDEKQSAT- 325

Query: 361 HMKRNQNLLEPRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGA 420
                  LL   +  +     L+ N   +L E                            
Sbjct: 326 ------TLLVGPRHGISHVIDLKTNLTTVLSEF--------------------------- 352

Query: 421 KYGISQVINSKLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESNSAKD 480
                    SK++ +    E   ++RVE +            + D K L LL+E   A +
Sbjct: 353 ---------SKISKIQLFRENQGVARVETS------------IMDAKPLVLLMEWPEATN 391

Query: 481 LACLIAGYYRLLVDPVTSIFLWPGNK 506
            ACLIAGY RLL+D    +F  P ++
Sbjct: 392 FACLIAGYCRLLLDSRKMVFSRPASQ 417



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 34/137 (24%), Positives = 58/137 (42%)

Query: 1408 LRQLKATPASTPEGFIQLMESLLELQDILETSWGVGNKHPPEKCTWHFTESRSRLCMGSQ 1467
            +  L+A     P+GF+       EL  +L           P+      +E +  L +  +
Sbjct: 1462 INALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEARAPKPYVSQISEYKLELALKFK 1521

Query: 1468 KLLSSCRHVIRMDQSPEEMQGAVRDTFQHLVQLAGLCFQFTDCSRCSARHREAAGNLRDV 1527
            +L +SCR V  +D+SP  M  A+  +FQ L  L     +     R  A+ +E    + +V
Sbjct: 1522 ELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEV 1581

Query: 1528 VYTYHQFIEAAKSTCER 1544
            V  Y   + AA+ +  R
Sbjct: 1582 VRNYTFLLRAAEESTAR 1598


>gi|27886590 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
           sapiens]
          Length = 1009

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 78/345 (22%), Positives = 157/345 (45%), Gaps = 32/345 (9%)

Query: 198 EANTTVKDIILTVKEKLSIRSIEYFALALEEQYSISRLHLLHEEELIQQVVEREE----S 253
           E    +  I+L+ +   +IR  E + L L+   S   +H LH +  + +V ++ E     
Sbjct: 66  EIREIITSILLSGRIGPNIRLAECYGLRLKHMKS-DEIHWLHPQMTVGEVQDKYECLHVE 124

Query: 254 HDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEMKCSSALRLAALHI 313
            ++R   ++ ++P+D ++ LKED     Y Y Q  +D +Q R+A ++    AL+L  L +
Sbjct: 125 AEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQ-RYASKVSEGMALQLGCLEL 183

Query: 314 Q---ERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISFHMKRNQNLLE 370
           +   + +   A  +K + + +EK+ G++ F    +  N+K K  +K I    ++  +L  
Sbjct: 184 RRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYASL-- 241

Query: 371 PRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGAKYGISQVINS 430
            R+++ +      + +   L          +   L +Q     + L++G K GI Q+ + 
Sbjct: 242 -REEECV------MKFFNTLAGFANIDQETYRCEL-IQGWNITVDLVIGPK-GIRQLTSQ 292

Query: 431 KLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESN--SAKDLACLIAGY 488
                + LAEF  I  +      E  +V+++ ++       +  S+   A+++A LI GY
Sbjct: 293 DAK-PTCLAEFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGY 351

Query: 489 YRLLVDPVTSIFLWP---GNKQQA------HRVSAEEGYESRACS 524
            RL  +   S+ + P   G K+ +        + A   + S +CS
Sbjct: 352 CRLQGEHQGSLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCS 396


>gi|27886588 PTK2B protein tyrosine kinase 2 beta isoform b [Homo
           sapiens]
          Length = 967

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 78/345 (22%), Positives = 157/345 (45%), Gaps = 32/345 (9%)

Query: 198 EANTTVKDIILTVKEKLSIRSIEYFALALEEQYSISRLHLLHEEELIQQVVEREE----S 253
           E    +  I+L+ +   +IR  E + L L+   S   +H LH +  + +V ++ E     
Sbjct: 66  EIREIITSILLSGRIGPNIRLAECYGLRLKHMKS-DEIHWLHPQMTVGEVQDKYECLHVE 124

Query: 254 HDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEMKCSSALRLAALHI 313
            ++R   ++ ++P+D ++ LKED     Y Y Q  +D +Q R+A ++    AL+L  L +
Sbjct: 125 AEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQ-RYASKVSEGMALQLGCLEL 183

Query: 314 Q---ERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISFHMKRNQNLLE 370
           +   + +   A  +K + + +EK+ G++ F    +  N+K K  +K I    ++  +L  
Sbjct: 184 RRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYASL-- 241

Query: 371 PRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGAKYGISQVINS 430
            R+++ +      + +   L          +   L +Q     + L++G K GI Q+ + 
Sbjct: 242 -REEECV------MKFFNTLAGFANIDQETYRCEL-IQGWNITVDLVIGPK-GIRQLTSQ 292

Query: 431 KLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESN--SAKDLACLIAGY 488
                + LAEF  I  +      E  +V+++ ++       +  S+   A+++A LI GY
Sbjct: 293 DAK-PTCLAEFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGY 351

Query: 489 YRLLVDPVTSIFLWP---GNKQQA------HRVSAEEGYESRACS 524
            RL  +   S+ + P   G K+ +        + A   + S +CS
Sbjct: 352 CRLQGEHQGSLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCS 396


>gi|27886586 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
           sapiens]
          Length = 1009

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 78/345 (22%), Positives = 157/345 (45%), Gaps = 32/345 (9%)

Query: 198 EANTTVKDIILTVKEKLSIRSIEYFALALEEQYSISRLHLLHEEELIQQVVEREE----S 253
           E    +  I+L+ +   +IR  E + L L+   S   +H LH +  + +V ++ E     
Sbjct: 66  EIREIITSILLSGRIGPNIRLAECYGLRLKHMKS-DEIHWLHPQMTVGEVQDKYECLHVE 124

Query: 254 HDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEMKCSSALRLAALHI 313
            ++R   ++ ++P+D ++ LKED     Y Y Q  +D +Q R+A ++    AL+L  L +
Sbjct: 125 AEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQ-RYASKVSEGMALQLGCLEL 183

Query: 314 Q---ERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISFHMKRNQNLLE 370
           +   + +   A  +K + + +EK+ G++ F    +  N+K K  +K I    ++  +L  
Sbjct: 184 RRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYASL-- 241

Query: 371 PRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGAKYGISQVINS 430
            R+++ +      + +   L          +   L +Q     + L++G K GI Q+ + 
Sbjct: 242 -REEECV------MKFFNTLAGFANIDQETYRCEL-IQGWNITVDLVIGPK-GIRQLTSQ 292

Query: 431 KLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESN--SAKDLACLIAGY 488
                + LAEF  I  +      E  +V+++ ++       +  S+   A+++A LI GY
Sbjct: 293 DAK-PTCLAEFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGY 351

Query: 489 YRLLVDPVTSIFLWP---GNKQQA------HRVSAEEGYESRACS 524
            RL  +   S+ + P   G K+ +        + A   + S +CS
Sbjct: 352 CRLQGEHQGSLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCS 396


>gi|27886584 PTK2B protein tyrosine kinase 2 beta isoform a [Homo
           sapiens]
          Length = 1009

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 78/345 (22%), Positives = 157/345 (45%), Gaps = 32/345 (9%)

Query: 198 EANTTVKDIILTVKEKLSIRSIEYFALALEEQYSISRLHLLHEEELIQQVVEREE----S 253
           E    +  I+L+ +   +IR  E + L L+   S   +H LH +  + +V ++ E     
Sbjct: 66  EIREIITSILLSGRIGPNIRLAECYGLRLKHMKS-DEIHWLHPQMTVGEVQDKYECLHVE 124

Query: 254 HDYRCLFRVCFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEMKCSSALRLAALHI 313
            ++R   ++ ++P+D ++ LKED     Y Y Q  +D +Q R+A ++    AL+L  L +
Sbjct: 125 AEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQ-RYASKVSEGMALQLGCLEL 183

Query: 314 Q---ERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISFHMKRNQNLLE 370
           +   + +   A  +K + + +EK+ G++ F    +  N+K K  +K I    ++  +L  
Sbjct: 184 RRFFKDMPHNALDKKSNFELLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYASL-- 241

Query: 371 PRQKQLISAAQLRLNYLQILGELKTYGGRIFNATLMLQDRESYIALLVGAKYGISQVINS 430
            R+++ +      + +   L          +   L +Q     + L++G K GI Q+ + 
Sbjct: 242 -REEECV------MKFFNTLAGFANIDQETYRCEL-IQGWNITVDLVIGPK-GIRQLTSQ 292

Query: 431 KLNIMSTLAEFANISRVELTEESEKVSVVKVYLQDVKVLTLLLESN--SAKDLACLIAGY 488
                + LAEF  I  +      E  +V+++ ++       +  S+   A+++A LI GY
Sbjct: 293 DAK-PTCLAEFKQIRSIRCLPLEEGQAVLQLGIEGAPQALSIKTSSLAEAENMADLIDGY 351

Query: 489 YRLLVDPVTSIFLWP---GNKQQA------HRVSAEEGYESRACS 524
            RL  +   S+ + P   G K+ +        + A   + S +CS
Sbjct: 352 CRLQGEHQGSLIIHPRKDGEKRNSLPQIPMLNLEARRSHLSESCS 396


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 57/243 (23%), Positives = 102/243 (41%), Gaps = 8/243 (3%)

Query: 574 STCGASSTTDSAESEASDSANTESR-GYRTSGSSESMDALEEDDLDTCSSSRSTFFHFGS 632
           S   +SS +DS++S++SDS++++S     +S SS+S D+ +  D    S S+S      S
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD----SS 627

Query: 633 PGLAESIDSDSQEERSGIETSGFLCLLDLAQRANPQCQKTEFSESAALETFGWAPEL-ST 691
              ++S DSDS+ + S   +S      D +  +N          S + ++   +    S+
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687

Query: 692 VRLDPRLYEGSHADYYSLCSSVSPASYLSDSSESTASRQGGAPPAWGQQGWTEAQPSSML 751
              D      S     S  SS S +S  SDSS S +S    +  +        +  S   
Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747

Query: 752 EPLALHPPLAFEDGSSDEEYYDAADK--LTPPGPPSGPRDVSTAEPSATSLQNKASTSSP 809
           +           D S+  +  D++D    +     S   D S +  S+ S  +  S++S 
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807

Query: 810 ENS 812
           ++S
Sbjct: 808 DSS 810



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 52/236 (22%), Positives = 98/236 (41%), Gaps = 20/236 (8%)

Query: 578 ASSTTDSAESEASDSANTESRGYRTSGSSESMDAL-EEDDLDTCSSSRSTFFHFGSPGLA 636
           +S ++DS  S++SDS+N+ S    +S SS+S D+    D  D+  SS S+     S    
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763

Query: 637 ESIDSDSQEERSGIETSGFLCLLDLAQRANPQCQKTEFSESAALETFGWAPELSTVRLDP 696
            S  SDS +     ++S        +  +N     ++ S+S+       + + S+   D 
Sbjct: 764 SSDSSDSSDSSDSSDSSN-------SSDSNDSSNSSDSSDSSNSSDSSNSSD-SSDSSDS 815

Query: 697 RLYEGSHADYYSLCSSVSPASYLSDSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLAL 756
              + S++   S  S  S +S  SDSS+S+ S  G    +  +   + +  SS       
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS------- 868

Query: 757 HPPLAFEDGSSDEEYYDAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTSSPENS 812
                  D S+  +  D++D              ++++  ++   N + +S   NS
Sbjct: 869 ----DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 55/231 (23%), Positives = 101/231 (43%), Gaps = 27/231 (11%)

Query: 582 TDSAESEASDSANTESRGYRTSGSSESMDALEEDDLDTCSSSRSTFFHFGSPGLAESIDS 641
           +DS++S++SDS+N          SS+S D+ + D  D+ SSS S      S   ++S DS
Sbjct: 547 SDSSDSDSSDSSN----------SSDSSDSSDSDSSDSNSSSDSDSSDSDS---SDSSDS 593

Query: 642 DSQEERSGIETSGFLCLLDLAQRANPQCQKTEFSESAALETFGWAPELSTVRLDPRLYEG 701
           DS +  +  ++S      D +  ++    K++ S+S +  +   +   S+        + 
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN 653

Query: 702 SHADYYSLCSSVSPASYLSDSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHPPLA 761
           S +   S  S+ S +S  SDSS+S++S              +++  SS     +     +
Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSS--------------SDSSNSSDSSDSSDSSNSS 699

Query: 762 FEDGSSDEEYYDAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTSSPENS 812
               SSD    D++D        S   D S +  S+ S  +  S+ S ++S
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSS 750



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 69/306 (22%), Positives = 120/306 (39%), Gaps = 31/306 (10%)

Query: 519 ESRACSDSEESSEVDCVLEPLSDRRLVKLAPCRSLIKEEQPPGNSPTPEVARRGPSTCGA 578
           +S   SDS +SS+     +  SD    +     S  K +    NS           +  +
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS 662

Query: 579 SSTTDSAESE-------ASDSANT--ESRGYRTSGSSESMDALEEDDLDTCSSSRSTFFH 629
           S+++DS++S        +SDS+N+   S    +S SSES D+ +  D D+  SS S+   
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS--- 719

Query: 630 FGSPGLAESIDSDSQEERSGIETSGFLCLLDLAQRAN--PQCQKTEFSESAALETFGWAP 687
                 + S DSDS       ++S      D +  +N       ++ S S+       + 
Sbjct: 720 -----NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774

Query: 688 ELSTVRLDPRLYEGSHADYYSLCSSVSPASYLSDSSESTASRQGGAPPAWGQQGWTEAQP 747
           + S         + S++   S  S+ S +S  SDSS+S+ S    +  +      +++  
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834

Query: 748 SSMLEPLALHPPLAFEDGSSDEEYYDAADK-LTPPGPPSGPRDVSTAEPSATSLQNKAST 806
           SS              D S   +  D +D   +     S   D S +  S+ S  +  S+
Sbjct: 835 SS-----------NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSS 883

Query: 807 SSPENS 812
            S E+S
Sbjct: 884 DSNESS 889



 Score = 38.5 bits (88), Expect = 0.052
 Identities = 60/294 (20%), Positives = 117/294 (39%), Gaps = 15/294 (5%)

Query: 519  ESRACSDSEESSEVDCVLEPLSDRRLVKLAPCRSLIKEEQPPGNSPTPEVARRGPSTCGA 578
            +S   SDS + S+ D      S+R     +   S   +     +S     +    ++  +
Sbjct: 840  DSSDSSDSSDGSDSDS-----SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDS 894

Query: 579  SSTTDSAESEASDSANTESRGYRTSGSSESMDALEEDDLDTCSSSRSTFFHFGSPGLAES 638
            S +++S++S++SDS+N+ S    +S SS+S ++    D    S S ++     S   + S
Sbjct: 895  SDSSNSSDSDSSDSSNS-SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953

Query: 639  IDSDSQEERSGIETSGFLCLLDLAQRANPQCQKTEFSESAALETFGWAPELSTVRLDPRL 698
             DS +  + S    S      D +  +N     ++ S+S+       + + S        
Sbjct: 954  SDSSNSSDSSNSSDSSDSNSSDSSDSSN----SSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009

Query: 699  YEGSHADYYSLCSSVSPASYLSDSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHP 758
             + S +   S  S+ S +S  SDSS+S+ S              +++  SS     +   
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS-----DSSDSSDSSDSSNSSDSSDSS 1064

Query: 759  PLAFEDGSSDEEYYDAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTSSPENS 812
              +    SSD      + + +     S   D S +  S+ S  +  S+ S ++S
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 37/151 (24%), Positives = 68/151 (45%), Gaps = 8/151 (5%)

Query: 578  ASSTTDSAESEASDSANTESRGYRTSGSSESMDALE-EDDLDTCSSSRSTFFHFGSPGLA 636
            +S+++DS++S  S  ++  S    +S SSES D+ +  D  D+  SS S+     S    
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179

Query: 637  ESIDSDSQEERSGIETSGFLCLLDLAQRANPQCQKTEFSESAALETFGWAPELSTVRLDP 696
             S  SDS +     ++S        +  ++     ++ S+S+       + + S      
Sbjct: 1180 SSDSSDSSDSSDSSDSSD-------SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232

Query: 697  RLYEGSHADYYSLCSSVSPASYLSDSSESTA 727
               + S +   S  S+ S +S  SDSS+ST+
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263



 Score = 35.8 bits (81), Expect = 0.34
 Identities = 54/249 (21%), Positives = 99/249 (39%), Gaps = 26/249 (10%)

Query: 578  ASSTTDSAESEASDSANTESRGYRTSGSSESMDALEEDDLDTCSSSRSTFFHFGSPGLAE 637
            +S+++DS++S  S  ++  S    +S SSES D+   D  ++  SS S+     S     
Sbjct: 1054 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS--SDSSNSSDSSDSSDSSDSSDSSDS 1111

Query: 638  SIDSDSQEERSGIETSGFLCLLDLAQRANPQCQKTEFSESAALETFGWAPELSTVRLDPR 697
            S  SDS +  +  ++S      D +  +N     ++ SES+       + + S       
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSN-SSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170

Query: 698  LYEGSHADYYSLCSSVSPASYLSDSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALH 757
              + S +   S  S  S +S  SDSS+S+ S              +++  SS        
Sbjct: 1171 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS--------SDSSDSS-------- 1214

Query: 758  PPLAFEDGSSDEEYYDAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTSSPENSLPCGP 817
                  D S   +  D++D  +     S   D S +  S+ S  +  S+ S +++     
Sbjct: 1215 ------DSSDSSDSSDSSDS-SDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267

Query: 818  DGRQPSRRG 826
            +    S+ G
Sbjct: 1268 ESDSQSKSG 1276



 Score = 32.3 bits (72), Expect = 3.7
 Identities = 44/241 (18%), Positives = 88/241 (36%), Gaps = 2/241 (0%)

Query: 926  ETMETKSVIDSRVSSISAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSGPDTAQAR 985
            ++ ++ +  +S  SS S+     D ++  NS    + SS++S    S+  S   D++ + 
Sbjct: 691  DSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSS 750

Query: 986  PSQILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDPNPDRACLASNPGLNNVSQGDTLELQ 1045
             S     S D    +    + +  DSS S +S D N       S+   N+    ++ +  
Sbjct: 751  NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS 810

Query: 1046 LEPHVQLEMGLESFCTNHIQETAPKYTEPLLSPRDEPR--SDECGINPGEKIASIPTKEE 1103
                        S  +++  +++        S   +    SD    N  +   S  + + 
Sbjct: 811  DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDS 870

Query: 1104 PQGQLSLERDREVTNKNGTNVFQEESRKDSGDSPGDVSNNVSQTLDISSPAGKIVTSLSL 1163
                 S +      +   +N        +S DS    S+N S + D S+ +    +S S 
Sbjct: 871  SDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSS 930

Query: 1164 D 1164
            D
Sbjct: 931  D 931



 Score = 32.3 bits (72), Expect = 3.7
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 2/89 (2%)

Query: 562  NSPTPEVARRGPSTCGASSTTDSAESEASDSANT--ESRGYRTSGSSESMDALEEDDLDT 619
            +S + + +    S+  + S+  S  S++SDS+N+   S    +S SS+S D+ +  D   
Sbjct: 1147 SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1206

Query: 620  CSSSRSTFFHFGSPGLAESIDSDSQEERS 648
             S S  +     S   ++S DS    E S
Sbjct: 1207 SSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235


>gi|122937249 glutamate receptor interacting protein 2 [Homo sapiens]
          Length = 1141

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 30/82 (36%), Positives = 43/82 (52%), Gaps = 4/82 (4%)

Query: 56   HTVKIDKDTLLQDYGFHISESL---PLTVVAVTAGGSAH-GKLFPGDQILQMNNEPAEDL 111
            H V + KD +  D+GF +S+ L    + V  V   G AH G L P D++LQ+N+    D 
Sbjct: 1038 HKVTLHKDPMRHDFGFSVSDGLLEKGVYVHTVRPDGPAHRGGLQPFDRVLQVNHVRTRDF 1097

Query: 112  SWERAVDILREAEDSLSITVVR 133
                AV +L EA D L + + R
Sbjct: 1098 DCCLAVPLLAEAGDVLELIISR 1119



 Score = 37.7 bits (86), Expect = 0.089
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 2/56 (3%)

Query: 78  PLTVVAVTAGGSAH--GKLFPGDQILQMNNEPAEDLSWERAVDILREAEDSLSITV 131
           PL +  +  G  AH  G L PGD++L ++N   ++   E AV ILR+ ED + + +
Sbjct: 680 PLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCPMEDAVQILRQCEDLVKLKI 735


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 132/651 (20%), Positives = 219/651 (33%), Gaps = 82/651 (12%)

Query: 560  PGNSPTPEVARRGPSTCGASSTTDS----AESEASDSANTESRGYRTSGSSESMDALEED 615
            P ++ TP ++R   ++  +  +TD+    A +  S S+   +  + +SGS+++  AL   
Sbjct: 3650 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDT--ALSPG 3707

Query: 616  DLDTCS-SSRSTFFHFGSPGLAESIDSDSQEERSGI---------ETSGFLCLLDLAQRA 665
                 S    ST FH  SPG   +         SGI          T      L  A   
Sbjct: 3708 STTALSFGQESTTFH-SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 3766

Query: 666  NP--QCQKTEF-SESAALETFGWAP--------ELSTVRLDPRLYEGSHADYYSLCSSVS 714
            +P  Q + T F +  A+  T    P        E +T    P     +H    S  S  S
Sbjct: 3767 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 3826

Query: 715  PASYL----SDSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSSDEE 770
              S +     D+S +T S         G+   +   P S    +   P      G S+  
Sbjct: 3827 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS--TEITTLPGSTTTPGLSEAS 3884

Query: 771  --YYDAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTSSPENSLPCGPDGRQPSRRGGV 828
              +Y +    T    P+    +   E S TS     ST S  +           +   G+
Sbjct: 3885 TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP--------ASTTTPGL 3936

Query: 829  KKYAKTLRKRRSFLQTDYTSQVSFPLVPSASLESVDDVCYYDR--EPYLALGAPSPTVSS 886
             + + T+           T    FP   + S+   +   ++ R    +  L     T S 
Sbjct: 3937 SEESTTVYSS----SPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSG 3992

Query: 887  LQD----MQGEPGLLETKALGLL--APLRETKSTNPA---SRVMEMEPETMETKSVIDSR 937
            L +      G P   +T     L  A L E  +T P+   S   ++ P    T  ++   
Sbjct: 3993 LTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGES 4052

Query: 938  VSSISAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSGPDTAQARPSQILPLSQDLD 997
              S      R+ P++ E +        S +TP  S   ++   + ++  + + P +    
Sbjct: 4053 TPS------RLSPSSTETT----TLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 4102

Query: 998  GIAPKEPTIEHGDSSFSLSSGDPNPDRACLASNPGLNNVSQGDTLELQLEPHVQLEMGLE 1057
            G++ +  T      S   ++   +   + L+  P  ++ SQG T E  L P       L 
Sbjct: 4103 GVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGST-EATLSPGSTTASSLG 4161

Query: 1058 SFCTNHIQETAPKYTEPLLSPRDEPRSDECGINPGEKIASIPTKEEPQGQLSLERDREVT 1117
               T     ++P  TE  L P D        I  G   AS PT        SL       
Sbjct: 4162 QQSTTF--HSSPGDTETTLLPDDT-------ITSGLVEASTPTHSSTG---SLHTTLTPA 4209

Query: 1118 NKNGTNVFQEESRKDSGDSPGDVSNNVSQTLDISSPAGKIVTSLSLDAPVT 1168
            +   T + +E +   S  S  D + +   T  +         S     P T
Sbjct: 4210 SSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTT 4260



 Score = 40.0 bits (92), Expect = 0.018
 Identities = 122/581 (20%), Positives = 198/581 (34%), Gaps = 75/581 (12%)

Query: 560  PGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGYRTS-GSSESMDALEEDDLD 618
            P ++ TP ++R   ++  +  +TD+    AS + +  S+   TS  SS S D        
Sbjct: 1010 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGST 1069

Query: 619  TCSS--SRSTFFHFGSPGLAESIDSDSQEERSGI---------ETSGFLCLLDLAQRANP 667
            T  S    ST FH  +PG   +         SGI          T      L  A   +P
Sbjct: 1070 TALSFGQESTTFH-SNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 1128

Query: 668  --QCQKTEF-SESAALETFGWAP--------ELSTVRLDPRLYEGSHADYYSLCSSVSPA 716
              Q + T F +  A+  T    P        E +T    P     +H    S  S  S  
Sbjct: 1129 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 1188

Query: 717  SYL----SDSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSSDEE-- 770
            S +     D+S +T S         G+   +   P S    +   P      G S+    
Sbjct: 1189 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS--TEITTLPGSTTTPGLSEASTT 1246

Query: 771  YYDAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTSSPENSLPCGPDGRQPSRRGGVKK 830
            +Y +    T    P+    +   E S TS     ST S  +           +   G+ +
Sbjct: 1247 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP--------ASTTTPGLSE 1298

Query: 831  YAKTLRKRRSFLQTDYTSQVSFPLVPSASLESVDDVCYYDR--EPYLALGAPSPTVSSLQ 888
             + T+           T    FP   + S+   +   ++ R    +  L     T S L 
Sbjct: 1299 ESTTVYSS----SRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLT 1354

Query: 889  D----MQGEPGLLETKALGLL--APLRETKSTNPA---SRVMEMEPETMETKSVIDSRVS 939
            +      G P   +T     L  A L E  +T P+   S   ++ P    T  ++     
Sbjct: 1355 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTP 1414

Query: 940  SISAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGI 999
            S      R+ P++ E +        S +TP  S   ++   + ++  + + P +    G+
Sbjct: 1415 S------RLSPSSTETT----TLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 1464

Query: 1000 APKEPTIEHGDSSFSLSSGDPNPDRACLASNPGLNNVSQGDTLELQLEPHVQLEMGLESF 1059
            + +  T      S   ++   +   + L+  P  ++ SQG T E  L P       L   
Sbjct: 1465 SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGST-EATLSPGSTTASSLGQQ 1523

Query: 1060 CTNHIQETAPKYTEPLLSPRDEPRSDECGINPGEKIASIPT 1100
             T     ++P  TE  L P D        I  G   AS PT
Sbjct: 1524 STTF--HSSPGDTETTLLPDDT-------ITSGLVEASTPT 1555



 Score = 37.7 bits (86), Expect = 0.089
 Identities = 111/553 (20%), Positives = 188/553 (33%), Gaps = 56/553 (10%)

Query: 560  PGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGYRTSGSSE-SMDALEEDDLD 618
            P ++ TP ++R   ++  +  +TD+    AS + +  S+   TS SS  S D        
Sbjct: 2093 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGST 2152

Query: 619  TCSS--SRSTFFHFGSPGLAESIDSDSQEERSGI---------ETSGFLCLLDLAQRANP 667
            T  S    ST FH  SPG   +         SGI          T      L  A   +P
Sbjct: 2153 TALSFGQESTTFH-SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 2211

Query: 668  --QCQKTEF-SESAALETFGWAP--------ELSTVRLDPRLYEGSHADYYSLCSSVSPA 716
              Q + T F +  A+  T    P        E +T    P     +H    S  S  S  
Sbjct: 2212 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 2271

Query: 717  SYL----SDSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSSDEE-- 770
            S +     D+S +T S         G+   +   P S    +   P      G S+    
Sbjct: 2272 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS--TEITTLPGSTTTPGLSEASTT 2329

Query: 771  YYDAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTSSPENSLPCGPDGRQPSRRGGVKK 830
            +Y +    T    P+    +   E S TS     ST S  +           +   G+ +
Sbjct: 2330 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP--------ASTTTPGLSE 2381

Query: 831  YAKTLRKRRSFLQTDYTSQVSFPLVPSASLESVDDVCYYDR--EPYLALGAPSPTVSSL- 887
             + T+           T    FP  P+ S+   +   ++ R    +  L     T S L 
Sbjct: 2382 ESTTVYSS----SPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLT 2437

Query: 888  QDMQGEPGLLETKALGLLAPLRETKSTNPASRVMEMEPETMETKSVIDSRVSSI--SAIR 945
            ++    PG   +   GL A L        ++        T  T S   S  S +   +  
Sbjct: 2438 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTP 2497

Query: 946  FRIDPNNKENSGVVPAASSSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGIAPKEPT 1005
             R+ P++ E +        S +TP  S   ++   + ++  + + P +    G++ +  T
Sbjct: 2498 SRLSPSSTETT----TLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST 2553

Query: 1006 IEHGDSSFSLSSGDPNPDRACLASNPGLNNVSQGDTLELQLEPHVQLEMGLESFCTNHIQ 1065
                  S   ++   +     L+ +   ++ S G T    L          +   T+H  
Sbjct: 2554 SHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH-- 2611

Query: 1066 ETAPKYTEPLLSP 1078
             ++P  T+  LSP
Sbjct: 2612 -SSPGSTDTALSP 2623



 Score = 37.0 bits (84), Expect = 0.15
 Identities = 136/660 (20%), Positives = 221/660 (33%), Gaps = 92/660 (13%)

Query: 551  RSLIKEEQPPGNSPTPEVAR-----RGPSTCGA------------SSTTDSAESEASDSA 593
            +S I    P  +  TP  A      RG ST                STT    SEAS + 
Sbjct: 2745 KSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 2804

Query: 594  NTESRGYRTSGSSESMDALEEDDLDTCSSSRSTFFH-------FGSPGLAESIDSDSQEE 646
             +  R   T+ S  SM +L   +  T S S+    H         +PGL+E   +     
Sbjct: 2805 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2864

Query: 647  RSGIETSGFLCLLDLAQRANPQCQKTEFSESAALETFGWAPELSTVRL--DPRLYEGSHA 704
                ET+ F      + R       T  S  A+  T  +  + +T  L  +   + GS A
Sbjct: 2865 PGSTETTVFPRSTTTSVRGEE--PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 2922

Query: 705  DYYSLCSSVSPASYLSDSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHPPLAFED 764
               +   +    + L + S +  S  G           T +       P  L P      
Sbjct: 2923 STQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSP------ 2976

Query: 765  GSSDEEYYDAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTSSPENSLPCGPDGRQPSR 824
                     + +  T PG P+ P   S +E S T      S  SP+ +L         + 
Sbjct: 2977 --------SSTETTTLPGSPTTP---SLSEKSTTFY---TSPRSPDATL-----SPATTT 3017

Query: 825  RGGVKKYAKTLRKRRSFLQTDYTSQVSFPLVPSASLESVDDVCYYDREPYLALGAPSPTV 884
              GV + + T     S  Q   T   +FP   + S  S        +EP  +  +   T 
Sbjct: 3018 SSGVSEESST-----SHSQPGSTHTTAFPDSTTTSGLS--------QEPTASHSSQGSTE 3064

Query: 885  SSLQDMQGEPGLLETKALGLLAPLRETKSTNPASRVMEMEPETMETKSVIDSRV---SSI 941
            ++L      PG     +LG  +    T  ++P      + P+   T  ++++     SS 
Sbjct: 3065 ATL-----SPGSTTASSLGQQS---TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSST 3116

Query: 942  SAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGIAP 1001
             ++   + P +  ++G+   +++  S P  S+   S P T  A     + +S        
Sbjct: 3117 GSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP----VEVSTTYHSRPS 3172

Query: 1002 KEPTIEHGDSSFSLSSGDPNPDRACLASNPGLNNV----SQGDTLELQLEPHVQ-LEMGL 1056
              PT     SS +L   +   +   + S+PG        ++  T  L  EP    +  G 
Sbjct: 3173 STPTTHFSASSTTLGRSE---ESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGS 3229

Query: 1057 ESFCTNHIQETAPKYTEPLLSPRDEPRSDECGINPGEKIASIPTKEEPQGQLSLERDREV 1116
                      T    +E   +    PRS +  ++P    +S    EE     S       
Sbjct: 3230 TETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS-GVSEESTTSHSRPGSTHT 3288

Query: 1117 TNKNGTNVFQEESRKD--SGDSPGDVSNNVSQTLDISSPAGKIVTSLSLDAPVTGTEQIP 1174
            T   G+      S++   S  SPG     +S     +S  G   T+       T T  +P
Sbjct: 3289 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLP 3348



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 138/675 (20%), Positives = 215/675 (31%), Gaps = 87/675 (12%)

Query: 548  APCRSLIKEEQPPGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGY-RTSGSS 606
            AP        + PG++PT        +T G S  +    S    S  T S  +  TSG  
Sbjct: 1156 APVEESTTYHRSPGSTPTTHFP-ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 1214

Query: 607  ESMDAL---EEDDLDTCSSSRSTFFHFGSPGLAESIDSDSQEERSGIETSGFLCLLDLAQ 663
            ES  +       ++ T   S +T      PGL+E+  +     RS               
Sbjct: 1215 ESTTSRISPGSTEITTLPGSTTT------PGLSEASTTFYSSPRS--------------- 1253

Query: 664  RANPQCQKTEFSESAALETFGWAPELSTVRLDPRLYEGSHADYYSLCSSVSPASYLSDSS 723
                    T     A++ + G   E +T R  P    GS     S  S+ +P   LS+ S
Sbjct: 1254 -------PTTTLSPASMTSLGVGEESTTSRSQP----GSTHSTVSPASTTTPG--LSEES 1300

Query: 724  ESTASRQGGA------PPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSS-----DEEYY 772
             +  S   G+      P +       E   +    P + H  L  ED ++     +   +
Sbjct: 1301 TTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAF 1360

Query: 773  DAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTS---SPENSLPCGPDGRQ-PSRRGGV 828
              +   T  G P+        E S T   +  ST    SP  S   G  G   PSR    
Sbjct: 1361 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPS 1420

Query: 829  KKYAKTL--RKRRSFLQTDYTSQVSFPLVPSASLESV--------DDVCYYDREPYLALG 878
                 TL        L    T+  + P  P A+L           ++      +P     
Sbjct: 1421 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 1480

Query: 879  APSPTVSSLQDMQGEPGLLETKALGLLAPLRETKST----NPASRVMEMEPETMETKSVI 934
               P  ++  D+  EP    +      A L    +T       S      P   ET  + 
Sbjct: 1481 TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1540

Query: 935  DSRVSS--ISAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSGPDTAQARPS----- 987
            D  ++S  + A           ++ + PA+S+SA     S    S P ++   PS     
Sbjct: 1541 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTT 1600

Query: 988  -QILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDPNPDRACLASNPGLNNV----SQGDTL 1042
               + +S          PT     SS +L   +   +   + S+PG        ++  T 
Sbjct: 1601 AAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE---ESTTVHSSPGATGTALFPTRSATS 1657

Query: 1043 ELQLEPHVQ-LEMGLESFCTNHIQETAPKYTEPLLSPRDEPRSDECGINPGEKIASIPTK 1101
             L  EP    +  G           T    +E   +    PRS +  ++P    +S    
Sbjct: 1658 VLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS-GVS 1716

Query: 1102 EEPQGQLSLERDREVTNKNGTNVFQEESRKD--SGDSPGDVSNNVSQTLDISSPAGKIVT 1159
            EE     S       T   G+      S++   S  SPG     +S     +S  G   T
Sbjct: 1717 EESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPEST 1776

Query: 1160 SLSLDAPVTGTEQIP 1174
            +       T T  +P
Sbjct: 1777 TFHSSPGSTETTLLP 1791



 Score = 35.0 bits (79), Expect = 0.57
 Identities = 107/501 (21%), Positives = 173/501 (34%), Gaps = 85/501 (16%)

Query: 548  APCRSLIKEEQPPGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGY-RTSGSS 606
            AP        + PG++PT        +T G S  +    S    S  T S  +  TSG  
Sbjct: 3796 APVEESTTYHRSPGSTPTTHFP-ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 3854

Query: 607  ESMDAL---EEDDLDTCSSSRSTFFHFGSPGLAESIDSDSQEERSGIETSGFLCLLDLAQ 663
            ES  +       ++ T   S +T      PGL+E+  +     RS               
Sbjct: 3855 ESTTSRISPGSTEITTLPGSTTT------PGLSEASTTFYSSPRS--------------- 3893

Query: 664  RANPQCQKTEFSESAALETFGWAPELSTVRLDPRLYEGSHADYYSLCSSVSPASYLSDSS 723
                    T     A++ + G   E +T R  P    GS     S  S+ +P   LS+ S
Sbjct: 3894 -------PTTTLSPASMTSLGVGEESTTSRSQP----GSTHSTVSPASTTTPG--LSEES 3940

Query: 724  ESTASRQGGA------PPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSSDEEYYDAADK 777
             +  S   G+      P +       E   +    P + H  L  ED ++     ++   
Sbjct: 3941 TTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEEST-- 3998

Query: 778  LTPPGPPSGPRDVSTAEPS--ATSLQNKASTSSPENSLPCGPDGRQPSRRGGVKKYAKTL 835
                  P  P    T  P+   T+   + ST+ P +S   G     P+R        ++ 
Sbjct: 3999 ----AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTK-LSPARSTTSGLVGEST 4053

Query: 836  RKRRSFLQTDYTSQVSFPLVPSASLESVDDVCYY--DREPYLALGAPSPTVSSLQD---- 889
              R S   T+ T+    P  PS S +S     +Y   R P   L   + T S + +    
Sbjct: 4054 PSRLSPSSTETTTLPGSPTTPSLSEKS---TTFYTSPRSPDATLSPATTTSSGVSEESST 4110

Query: 890  MQGEPGLLETKAL---GLLAPLRETKSTNPASRVMEMEPETMETKSVIDSRVSSI--SAI 944
               +PG   T A       + L +  +T+ +S     +  T  T S   +  SS+   + 
Sbjct: 4111 SHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSS-----QGSTEATLSPGSTTASSLGQQST 4165

Query: 945  RFRIDPNNKENS----GVVPAASSSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGIA 1000
             F   P + E +      + +    ASTP  S+ GS          + + P S    G+ 
Sbjct: 4166 TFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS--------LHTTLTPASSTSTGLQ 4217

Query: 1001 PKEPTIEHGDSSFSLSSGDPN 1021
             +  T +   SS   +   P+
Sbjct: 4218 EESTTFQSWPSSSDTTPSPPS 4238



 Score = 32.3 bits (72), Expect = 3.7
 Identities = 116/532 (21%), Positives = 182/532 (34%), Gaps = 103/532 (19%)

Query: 548  APCRSLIKEEQPPGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGY-RTSGSS 606
            AP        + PG++PT        +T G S  +    S    S  T S  +  TSG  
Sbjct: 2239 APVEESTTYHRSPGSTPTTHFP-ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 2297

Query: 607  ESMDAL---EEDDLDTCSSSRSTFFHFGSPGLAESIDSDSQEERSGIETSGFLCLLDLAQ 663
            ES  +       ++ T   S +T      PGL+E+  +     RS               
Sbjct: 2298 ESTTSRISPGSTEITTLPGSTTT------PGLSEASTTFYSSPRS--------------- 2336

Query: 664  RANPQCQKTEFSESAALETFGWAPELSTVRLDPRLYEGSHADYYSLCSSVSPASYLSDSS 723
                    T     A++ + G   E +T R  P    GS     S  S+ +P   LS+ S
Sbjct: 2337 -------PTTTLSPASMTSLGVGEESTTSRSQP----GSTHSTVSPASTTTPG--LSEES 2383

Query: 724  ESTASRQGGA--------PPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSSDEEYYDAA 775
             +  S   G+         P    +G  E   +    P + H  L  ED ++     ++ 
Sbjct: 2384 TTVYSSSPGSTETTVFPRTPTTSVRG--EEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 2441

Query: 776  DKLTPPGPPSGPRDVSTAEPS--ATSLQNKASTSSPENSLPCGPDGRQPSRRGGVKKYAK 833
                    P  P    T  P+   T+   + ST+ P +S   G     P+R        +
Sbjct: 2442 ------AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTT-LSPARSTTSGLVGE 2494

Query: 834  TLRKRRSFLQTDYTSQVSFPLVPSASLESVDDVCYY--DREPYLALGAPSPTVSSLQD-- 889
            +   R S   T+ T+    P  PS S +S     +Y   R P   L   + T S + +  
Sbjct: 2495 STPSRLSPSSTETTTLPGSPTTPSLSEKS---TTFYTSPRSPDATLSPATTTSSGVSEES 2551

Query: 890  --MQGEPGLLETKAL------GLLAPLRETKSTNPASRVMEMEPETMETKSVIDSRVSSI 941
                 +PG   T A         L+    T  ++P S    + P +  T        +S 
Sbjct: 2552 STSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 2611

Query: 942  SAIRFRIDPNNKENS---GVVPAAS-SSASTPHCSNPGSSGPDTAQARPSQILPLSQDLD 997
            S+      P + + +   G   A S    ST   S+PGS+         + + P S    
Sbjct: 2612 SS------PGSTDTALSPGSTTALSFGQESTTFHSSPGST--------HTTLFPDSTTSS 2657

Query: 998  GIAPKEPTIEHGDSSFSLSSGDPNPDRACLAS-NPGLNNVSQGDTLELQLEP 1048
            GI      +         S+G P    +  +S +PGL    QG++   Q  P
Sbjct: 2658 GIVEASTRVHS-------STGSPRTTLSPASSTSPGL----QGESTTFQTHP 2698


>gi|55953110 retinoblastoma protein-binding zinc finger protein
            isoform c [Homo sapiens]
          Length = 1481

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 50/222 (22%)

Query: 878  GAPSPTVSSLQDMQGEPGLLETKAL--GLLAPLRETKSTNPASRVMEMEPETMETKSVID 935
            G P+PTV S  D+      L+T +L  G L PL     T+P+S      P      +V  
Sbjct: 731  GFPAPTVESTPDVCPSSPALQTPSLSSGQLPPL--LIPTDPSS-----PPPCPPVLTVAT 783

Query: 936  SRVSSISAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSG---------PDTAQARP 986
                 +  +              +PA SSSAS   C +P S+            T    P
Sbjct: 784  PPPPLLPTV-------------PLPAPSSSASPHPCPSPLSNATAQSPLPILSPTVSPSP 830

Query: 987  SQILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDPNPDRACLASNPGLNN----VSQGDTL 1042
            S I P+   +   +P  PT+    SS S SS   +   +   S P L+     VS GD L
Sbjct: 831  SPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNL 890

Query: 1043 ELQLEPHVQLEMGLESFCTNHIQETAPKYTEPLLSPRDEPRS 1084
            E  L         + SF    ++          L PR+EP+S
Sbjct: 891  EASLP--------MISFKQEELENEG-------LKPREEPQS 917


>gi|20336260 retinoblastoma protein-binding zinc finger protein
            isoform b [Homo sapiens]
          Length = 1682

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 50/222 (22%)

Query: 878  GAPSPTVSSLQDMQGEPGLLETKAL--GLLAPLRETKSTNPASRVMEMEPETMETKSVID 935
            G P+PTV S  D+      L+T +L  G L PL     T+P+S      P      +V  
Sbjct: 932  GFPAPTVESTPDVCPSSPALQTPSLSSGQLPPL--LIPTDPSS-----PPPCPPVLTVAT 984

Query: 936  SRVSSISAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSG---------PDTAQARP 986
                 +  +              +PA SSSAS   C +P S+            T    P
Sbjct: 985  PPPPLLPTV-------------PLPAPSSSASPHPCPSPLSNATAQSPLPILSPTVSPSP 1031

Query: 987  SQILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDPNPDRACLASNPGLNN----VSQGDTL 1042
            S I P+   +   +P  PT+    SS S SS   +   +   S P L+     VS GD L
Sbjct: 1032 SPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNL 1091

Query: 1043 ELQLEPHVQLEMGLESFCTNHIQETAPKYTEPLLSPRDEPRS 1084
            E  L         + SF    ++          L PR+EP+S
Sbjct: 1092 EASLP--------MISFKQEELENEG-------LKPREEPQS 1118


>gi|20336258 retinoblastoma protein-binding zinc finger protein
            isoform a [Homo sapiens]
          Length = 1718

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 60/222 (27%), Positives = 84/222 (37%), Gaps = 50/222 (22%)

Query: 878  GAPSPTVSSLQDMQGEPGLLETKAL--GLLAPLRETKSTNPASRVMEMEPETMETKSVID 935
            G P+PTV S  D+      L+T +L  G L PL     T+P+S      P      +V  
Sbjct: 932  GFPAPTVESTPDVCPSSPALQTPSLSSGQLPPL--LIPTDPSS-----PPPCPPVLTVAT 984

Query: 936  SRVSSISAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSG---------PDTAQARP 986
                 +  +              +PA SSSAS   C +P S+            T    P
Sbjct: 985  PPPPLLPTV-------------PLPAPSSSASPHPCPSPLSNATAQSPLPILSPTVSPSP 1031

Query: 987  SQILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDPNPDRACLASNPGLNN----VSQGDTL 1042
            S I P+   +   +P  PT+    SS S SS   +   +   S P L+     VS GD L
Sbjct: 1032 SPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSAISSVVSSGDNL 1091

Query: 1043 ELQLEPHVQLEMGLESFCTNHIQETAPKYTEPLLSPRDEPRS 1084
            E  L         + SF    ++          L PR+EP+S
Sbjct: 1092 EASLP--------MISFKQEELENEG-------LKPREEPQS 1118


>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
           interacting protein [Homo sapiens]
          Length = 1211

 Score = 42.7 bits (99), Expect = 0.003
 Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 1/56 (1%)

Query: 67  QDYGFHISESLPLTVVAVTAGGSAH-GKLFPGDQILQMNNEPAEDLSWERAVDILR 121
           +D+GF +  S P  V+ V  G SAH G L PGDQIL++       LS ER V + R
Sbjct: 15  EDFGFRLGGSGPCFVLEVAKGSSAHAGGLRPGDQILEVEGLAVGGLSRERLVRLAR 70


>gi|32479521 dishevelled 1 [Homo sapiens]
          Length = 670

 Score = 42.7 bits (99), Expect = 0.003
 Identities = 24/66 (36%), Positives = 40/66 (60%), Gaps = 5/66 (7%)

Query: 83  AVTAGGS--AHGKLFPGDQILQMNNEPAEDLSWERAVDILREAEDS---LSITVVRCTSG 137
           ++  GG+  A G++ PGD +LQ+N+   E++S + AV +LRE       +S+TV +C   
Sbjct: 282 SIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDP 341

Query: 138 VPKSSF 143
            P+S F
Sbjct: 342 TPRSYF 347


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score = 42.7 bits (99), Expect = 0.003
 Identities = 30/83 (36%), Positives = 38/83 (45%)

Query: 560 PGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGYRTSGSSESMDALEEDDLDT 619
           P    +P   R   S   AS    SA S AS SA++ S    +SGSS S D  E+D LD 
Sbjct: 349 PAAGRSPADHRGYASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDL 408

Query: 620 CSSSRSTFFHFGSPGLAESIDSD 642
             SS       GS   + ++D D
Sbjct: 409 NPSSNFESMSLGSFSSSSALDRD 431


>gi|4759306 lin-7 homolog A [Homo sapiens]
          Length = 233

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 36/110 (32%), Positives = 57/110 (51%), Gaps = 14/110 (12%)

Query: 70  GFHI----SESLPLTVVAVTAGGSA--HGKLFPGDQILQMNNEPAEDLSWERAVDILREA 123
           GF++     ++ P+ +  +  GG A  HG L  GDQ+L +N    E    E+AV++L+ A
Sbjct: 119 GFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAA 178

Query: 124 EDSLSITVVRCTSGVPKSSFLTEEKRARL-KTNPVKVHFAEEVLISGHSQ 172
           +DS+ + VVR T   PK   + EE  AR  K    +    +++LI    Q
Sbjct: 179 KDSVKL-VVRYT---PK---VLEEMEARFEKLRTARRRQQQQLLIQQQQQ 221


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score = 41.6 bits (96), Expect = 0.006
 Identities = 81/355 (22%), Positives = 120/355 (33%), Gaps = 60/355 (16%)

Query: 882  PTVSSLQDMQGEPGLLETKALGLLAPLRETKSTNPASRVMEMEPETMETKSVIDSRVSSI 941
            PT+S      G+P + E     +L    E  ST+         P T+ +K +  S   + 
Sbjct: 82   PTISEASSASGQPTISEGPGTSVLPTPSEGLSTSG--------PPTI-SKGLCTSVTLAA 132

Query: 942  SAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGIAP 1001
            S  R         N+   P +S   ST        S P TA   PS  LP +        
Sbjct: 133  SEGR---------NTSRPPTSSEEPST--------SVPPTASEVPSTSLPPTPGEGTSTS 175

Query: 1002 KEPTIEHGDSSFSLSSGDPNPDRACLAS---NPGLN---NVSQGDTLELQLEPHVQLEMG 1055
              PT   G S+  + + D  P  + L +    PG +     ++G +  +Q  P       
Sbjct: 176  VPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPSTS 235

Query: 1056 LESFCTNHIQETAPKYTEPLLSPRDEPRSDECGINPGEKIASIPTKEEPQGQ-LSLERDR 1114
            +    T  +    P         RDE  S      PGE  ++        GQ +SL   R
Sbjct: 236  VPPTATEGLSTPVPP-------TRDEGPSTSVPATPGEGPSTSVLPAASDGQSISLVPTR 288

Query: 1115 EVTNKNGTNVFQEESRKDSGDSPGDVSNNVSQTLDISSPAGKIVTSLSLDAPVTGTEQ-- 1172
                K  +      + +    S    +   S T    +P G + TS+    P T TE+  
Sbjct: 289  ---GKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSV----PPTATEELS 341

Query: 1173 --IPPHPPRDPQGQSREPPGQGCQAQEQKLFVELDLDPDFFLGKQTVSPAVPPEG 1225
              +PP P   P       PG+G         +   + P    G  T  P  P EG
Sbjct: 342  TSVPPTPGEGPSTSVLPIPGEG---------LSTSVPPTASDGSDTSVPPTPGEG 387


>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
          Length = 904

 Score = 41.2 bits (95), Expect = 0.008
 Identities = 24/67 (35%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 72  HISESLPLTVVAVTAGGSAH--GKLFPGDQILQMNNEPAEDLSWERAVDILREAEDSLSI 129
           HI     + V  +  GG+AH  GKL  GD++L +NN   E+++ E AV  L+   D + +
Sbjct: 341 HIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYL 400

Query: 130 TVVRCTS 136
            V + TS
Sbjct: 401 KVAKPTS 407



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 2/64 (3%)

Query: 72  HISESLPLTVVAVTAGGSA--HGKLFPGDQILQMNNEPAEDLSWERAVDILREAEDSLSI 129
           HI +   + +  +  GG+A   G+L   D IL++N     D++  +AV+ L+EA   + +
Sbjct: 246 HIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRL 305

Query: 130 TVVR 133
            V R
Sbjct: 306 YVKR 309


>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
          Length = 926

 Score = 41.2 bits (95), Expect = 0.008
 Identities = 24/67 (35%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 72  HISESLPLTVVAVTAGGSAH--GKLFPGDQILQMNNEPAEDLSWERAVDILREAEDSLSI 129
           HI     + V  +  GG+AH  GKL  GD++L +NN   E+++ E AV  L+   D + +
Sbjct: 341 HIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFVYL 400

Query: 130 TVVRCTS 136
            V + TS
Sbjct: 401 KVAKPTS 407



 Score = 33.9 bits (76), Expect = 1.3
 Identities = 19/64 (29%), Positives = 34/64 (53%), Gaps = 2/64 (3%)

Query: 72  HISESLPLTVVAVTAGGSA--HGKLFPGDQILQMNNEPAEDLSWERAVDILREAEDSLSI 129
           HI +   + +  +  GG+A   G+L   D IL++N     D++  +AV+ L+EA   + +
Sbjct: 246 HIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEALKEAGSIVRL 305

Query: 130 TVVR 133
            V R
Sbjct: 306 YVKR 309


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 673

 Score = 40.8 bits (94), Expect = 0.010
 Identities = 126/608 (20%), Positives = 196/608 (32%), Gaps = 64/608 (10%)

Query: 847  TSQVSFPLVPS-ASLESVDDVCYYDREPYLALGAPSPTVSSLQDMQGEPGLLETKALGLL 905
            TS  S  + PS ASL  +       R P +A     P  +S         L+   +   L
Sbjct: 62   TSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASL 121

Query: 906  --APLRETKSTNPASRVMEMEPETMETKSVIDSRVSSISAIRFRIDPNNKENSGVVPAAS 963
              +P R + +T P+   + M P T    ++  SR S       R  P  + +  + P+ +
Sbjct: 122  TRSPSRASLTTTPSRASLSMTPSTAAALTM-PSRASLT-----RTPP--RASLTMTPSTA 173

Query: 964  SSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDPNPD 1023
            S   TP  ++P           PS+  P          K  +      + S +S    P 
Sbjct: 174  SLTRTPPRASP--------TGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPP 225

Query: 1024 RACLASNPGLNNVSQ--GDTLELQLEPHVQLEMGLESFCTNHIQETAPKYTEP----LLS 1077
            RA    +P   ++S      L ++  P       L       +  TA     P      S
Sbjct: 226  RASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTAS 285

Query: 1078 PRDEPRSDECGINPGE-KIASIPTKEEPQGQLSLERDREVTNKNGT----------NVFQ 1126
            P   P      + P    +  +  +  P G LS      +T  + T          ++ +
Sbjct: 286  PTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRT---SLTKMDSTASISRTPPRASITR 342

Query: 1127 EESRKDSGDSPGDVS--NNVSQTLDISSPAGKIVTSLSLDAPVTGTEQIPPHPPR-DPQG 1183
              SR      P   S     S+     SP+   +T LS  A  TGT      PPR  P G
Sbjct: 343  TPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGT------PPRASPTG 396

Query: 1184 Q------SREPPGQ---GCQAQEQKLFVELDLDPDFFLGKQTVS---PAVPPEGIKAEAP 1231
                   +R+PP     G  ++     ++    P     + + +   P   P G  + A 
Sbjct: 397  TPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRAS 456

Query: 1232 NHVTGQDIAPRDSPEWVCFNPEPSLPEPLPCPQEDPHLETSNHCLLSEGKSDSSSICLSA 1291
               T    +P  SP        PS   P   P       T +   L++ +S +S     +
Sbjct: 457  PTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPS 516

Query: 1292 EKSFLCFAPESHPEVSASLRVATSLGFAGMNEMVAPRIGMDQCSCQFSYATCFRGPQPET 1351
              S       + P  S S  +A              R  + +   + S  T  R     T
Sbjct: 517  RASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRT 576

Query: 1352 EEEDRDLEAHPMAPLTSPPSAGSPVVLPWRPARAHSCTTAPLSRKSHIWPEYCSRALRQL 1411
                      P A  T  PS  SP  +P         +TA ++R     P   S      
Sbjct: 577  PSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRT----PPRASPTETPP 632

Query: 1412 KATPASTP 1419
            +A+P  TP
Sbjct: 633  RASPTGTP 640



 Score = 32.3 bits (72), Expect = 3.7
 Identities = 95/462 (20%), Positives = 150/462 (32%), Gaps = 73/462 (15%)

Query: 732  GAPPAWGQQGWTEAQPSSMLEPLAL---HPPLAFEDGSSDEEYYDAADKLTP-PGPPSGP 787
            G PP     G       SM+   AL    PP A   G          D        PS P
Sbjct: 222  GTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRP 281

Query: 788  RDVS-TAEPSATSLQNKASTSSPENSLP-CGPDGRQPSRRGGVKKYAKTLRKRRSFLQTD 845
               S T  PS  SL    ST+S    LP   P G               +  R S  + D
Sbjct: 282  STASPTGTPSRASLSMTPSTASLMRMLPRASPTG---------------MLSRTSLTKMD 326

Query: 846  YTSQVSFPLVPSASLESVDDVCYYDREPYLALGAPSPTVSSLQDMQGEPGL--LETKALG 903
             T+ +S    P AS+           +P  A    +P+ +S         L  L + A  
Sbjct: 327  STASIS-RTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASP 385

Query: 904  LLAPLRETKSTNPASRVMEMEPETMETKSVIDSRVSSISAIRFRIDPNNKENSGVVPAAS 963
               P R + +  P++  +  +P       ++    +SI+ +     P         P AS
Sbjct: 386  TGTPPRASPTGTPSTASLTRKPPRASPTGMLSR--TSITKMDSTASPTRTP-----PRAS 438

Query: 964  SSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDPNPD 1023
             + + P  S  G+         PS+  P            P+      S S +S   +P 
Sbjct: 439  PTGTPPRASPTGT---------PSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPS 489

Query: 1024 RACLASNPGLNNVSQGDTLELQLEPHVQLEMGLESFCTNHIQETAPKYTEPLLSPRDEPR 1083
            RA L   P   +++               +M   +  T      +P +T    SP   P 
Sbjct: 490  RASLTRTPSRASLT---------------KMESTASITRTPSRASPTWTPSTASPTGSPS 534

Query: 1084 SDECGINPGEKIASIPTKEEPQGQLSLERDR-EVTNKNGTNVFQEES-----RKDSGDSP 1137
            +    +  G    +  T+   +  L+    R  +T  +  ++ +  S     R     SP
Sbjct: 535  T---ALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASP 591

Query: 1138 GDVSNNVSQTLDISSPAGKIVTSLSLDAPVTGTEQIPPHPPR 1179
              + +  S T     P+  ++T +   A +T T      PPR
Sbjct: 592  TGMPSRTSPT---GMPSSALLTKMDSTASITRT------PPR 624


>gi|21071018 epidermal growth factor receptor pathway substrate
           8-like protein 3 isoform a [Homo sapiens]
          Length = 594

 Score = 40.8 bits (94), Expect = 0.010
 Identities = 45/168 (26%), Positives = 69/168 (41%), Gaps = 17/168 (10%)

Query: 654 GFLCLLDLAQRANPQCQKTEFSES--AALETFGWAPELSTVRLDPRL-------YEGSHA 704
           G+L LLD+  +      + +  ++   AL T  +   LS    +P L       ++    
Sbjct: 75  GWLQLLDIETKEELDSYRLDSIQAMNVALNTCSYNSILSITVQEPGLPGTSTLLFQCQEV 134

Query: 705 DYYSLCSSVSPASYLSDSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHPPLAFED 764
               L +S+  A  L +  E +  R GG  P  GQ  W   +  +M  PL +      E 
Sbjct: 135 GAERLKTSLQKA--LEEELEQSRPRLGGLQP--GQDRW---RGPAMERPLPMEQARYLEP 187

Query: 765 GSSDEEYYDAA-DKLTPPGPPSGPRDVSTAEPSATSLQNKASTSSPEN 811
           G   E+ +    +   PP P   PR  S  EPSA +L     +SSPE+
Sbjct: 188 GIPPEQPHQRTLEHSLPPSPRPLPRHTSAREPSAFTLPPPRRSSSPED 235


>gi|239756829 PREDICTED: zinc finger protein 385C [Homo sapiens]
          Length = 1082

 Score = 40.0 bits (92), Expect = 0.018
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 4/84 (4%)

Query: 739 QQGWTEAQPSSMLEPLALHPPLAFEDGSSDEEYYDAADKLTPPGPPSGPRDVSTAEPSAT 798
           Q+  T+AQ  +++ P+   P LA       +    AA  L PP  P    D +  EP+ +
Sbjct: 775 QRPHTQAQDGAVVSPI---PTLASGAPGEPQSKVPAAPPLGPPLQPPPTPDPTCREPAHS 831

Query: 799 SLQNKASTSSPENSLPCGPD-GRQ 821
            L + AS+SS  +  PC P+ GR+
Sbjct: 832 ELLDAASSSSSSSCPPCSPEPGRE 855


>gi|239751322 PREDICTED: zinc finger protein 385C [Homo sapiens]
          Length = 1082

 Score = 40.0 bits (92), Expect = 0.018
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 4/84 (4%)

Query: 739 QQGWTEAQPSSMLEPLALHPPLAFEDGSSDEEYYDAADKLTPPGPPSGPRDVSTAEPSAT 798
           Q+  T+AQ  +++ P+   P LA       +    AA  L PP  P    D +  EP+ +
Sbjct: 775 QRPHTQAQDGAVVSPI---PTLASGAPGEPQSKVPAAPPLGPPLQPPPTPDPTCREPAHS 831

Query: 799 SLQNKASTSSPENSLPCGPD-GRQ 821
            L + AS+SS  +  PC P+ GR+
Sbjct: 832 ELLDAASSSSSSSCPPCSPEPGRE 855


>gi|239745821 PREDICTED: zinc finger protein 385C [Homo sapiens]
          Length = 1082

 Score = 40.0 bits (92), Expect = 0.018
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 4/84 (4%)

Query: 739 QQGWTEAQPSSMLEPLALHPPLAFEDGSSDEEYYDAADKLTPPGPPSGPRDVSTAEPSAT 798
           Q+  T+AQ  +++ P+   P LA       +    AA  L PP  P    D +  EP+ +
Sbjct: 775 QRPHTQAQDGAVVSPI---PTLASGAPGEPQSKVPAAPPLGPPLQPPPTPDPTCREPAHS 831

Query: 799 SLQNKASTSSPENSLPCGPD-GRQ 821
            L + AS+SS  +  PC P+ GR+
Sbjct: 832 ELLDAASSSSSSSCPPCSPEPGRE 855


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 40.0 bits (92), Expect = 0.018
 Identities = 122/581 (20%), Positives = 198/581 (34%), Gaps = 75/581 (12%)

Query: 560  PGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGYRTS-GSSESMDALEEDDLD 618
            P ++ TP ++R   ++  +  +TD+    AS + +  S+   TS  SS S D        
Sbjct: 497  PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGST 556

Query: 619  TCSS--SRSTFFHFGSPGLAESIDSDSQEERSGI---------ETSGFLCLLDLAQRANP 667
            T  S    ST FH  +PG   +         SGI          T      L  A   +P
Sbjct: 557  TALSFGQESTTFH-SNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 615

Query: 668  --QCQKTEF-SESAALETFGWAP--------ELSTVRLDPRLYEGSHADYYSLCSSVSPA 716
              Q + T F +  A+  T    P        E +T    P     +H    S  S  S  
Sbjct: 616  GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 675

Query: 717  SYL----SDSSESTASRQGGAPPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSSDEE-- 770
            S +     D+S +T S         G+   +   P S    +   P      G S+    
Sbjct: 676  STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS--TEITTLPGSTTTPGLSEASTT 733

Query: 771  YYDAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTSSPENSLPCGPDGRQPSRRGGVKK 830
            +Y +    T    P+    +   E S TS     ST S  +           +   G+ +
Sbjct: 734  FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSP--------ASTTTPGLSE 785

Query: 831  YAKTLRKRRSFLQTDYTSQVSFPLVPSASLESVDDVCYYDR--EPYLALGAPSPTVSSLQ 888
             + T+           T    FP   + S+   +   ++ R    +  L     T S L 
Sbjct: 786  ESTTVYSS----SRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLT 841

Query: 889  D----MQGEPGLLETKALGLL--APLRETKSTNPA---SRVMEMEPETMETKSVIDSRVS 939
            +      G P   +T     L  A L E  +T P+   S   ++ P    T  ++     
Sbjct: 842  EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTP 901

Query: 940  SISAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSGPDTAQARPSQILPLSQDLDGI 999
            S      R+ P++ E +        S +TP  S   ++   + ++  + + P +    G+
Sbjct: 902  S------RLSPSSTETT----TLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 951

Query: 1000 APKEPTIEHGDSSFSLSSGDPNPDRACLASNPGLNNVSQGDTLELQLEPHVQLEMGLESF 1059
            + +  T      S   ++   +   + L+  P  ++ SQG T E  L P       L   
Sbjct: 952  SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGST-EATLSPGSTTASSLGQQ 1010

Query: 1060 CTNHIQETAPKYTEPLLSPRDEPRSDECGINPGEKIASIPT 1100
             T     ++P  TE  L P D        I  G   AS PT
Sbjct: 1011 STTF--HSSPGDTETTLLPDDT-------ITSGLVEASTPT 1042



 Score = 36.2 bits (82), Expect = 0.26
 Identities = 138/675 (20%), Positives = 215/675 (31%), Gaps = 87/675 (12%)

Query: 548  APCRSLIKEEQPPGNSPTPEVARRGPSTCGASSTTDSAESEASDSANTESRGY-RTSGSS 606
            AP        + PG++PT        +T G S  +    S    S  T S  +  TSG  
Sbjct: 643  APVEESTTYHRSPGSTPTTHFP-ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 701

Query: 607  ESMDAL---EEDDLDTCSSSRSTFFHFGSPGLAESIDSDSQEERSGIETSGFLCLLDLAQ 663
            ES  +       ++ T   S +T      PGL+E+  +     RS               
Sbjct: 702  ESTTSRISPGSTEITTLPGSTTT------PGLSEASTTFYSSPRS--------------- 740

Query: 664  RANPQCQKTEFSESAALETFGWAPELSTVRLDPRLYEGSHADYYSLCSSVSPASYLSDSS 723
                    T     A++ + G   E +T R  P    GS     S  S+ +P   LS+ S
Sbjct: 741  -------PTTTLSPASMTSLGVGEESTTSRSQP----GSTHSTVSPASTTTPG--LSEES 787

Query: 724  ESTASRQGGA------PPAWGQQGWTEAQPSSMLEPLALHPPLAFEDGSS-----DEEYY 772
             +  S   G+      P +       E   +    P + H  L  ED ++     +   +
Sbjct: 788  TTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAF 847

Query: 773  DAADKLTPPGPPSGPRDVSTAEPSATSLQNKASTS---SPENSLPCGPDGRQ-PSRRGGV 828
              +   T  G P+        E S T   +  ST    SP  S   G  G   PSR    
Sbjct: 848  PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPS 907

Query: 829  KKYAKTL--RKRRSFLQTDYTSQVSFPLVPSASLESV--------DDVCYYDREPYLALG 878
                 TL        L    T+  + P  P A+L           ++      +P     
Sbjct: 908  STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 967

Query: 879  APSPTVSSLQDMQGEPGLLETKALGLLAPLRETKST----NPASRVMEMEPETMETKSVI 934
               P  ++  D+  EP    +      A L    +T       S      P   ET  + 
Sbjct: 968  TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1027

Query: 935  DSRVSS--ISAIRFRIDPNNKENSGVVPAASSSASTPHCSNPGSSGPDTAQARPS----- 987
            D  ++S  + A           ++ + PA+S+SA     S    S P ++   PS     
Sbjct: 1028 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTT 1087

Query: 988  -QILPLSQDLDGIAPKEPTIEHGDSSFSLSSGDPNPDRACLASNPGLNNV----SQGDTL 1042
               + +S          PT     SS +L   +   +   + S+PG        ++  T 
Sbjct: 1088 AAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE---ESTTVHSSPGATGTALFPTRSATS 1144

Query: 1043 ELQLEPHVQ-LEMGLESFCTNHIQETAPKYTEPLLSPRDEPRSDECGINPGEKIASIPTK 1101
             L  EP    +  G           T    +E   +    PRS +  ++P    +S    
Sbjct: 1145 VLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS-GVS 1203

Query: 1102 EEPQGQLSLERDREVTNKNGTNVFQEESRKD--SGDSPGDVSNNVSQTLDISSPAGKIVT 1159
            EE     S       T   G+      S++   S  SPG     +S     +S  G   T
Sbjct: 1204 EESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPEST 1263

Query: 1160 SLSLDAPVTGTEQIP 1174
            +       T T  +P
Sbjct: 1264 TFHSSPGSTETTLLP 1278


>gi|11545920 lin-7 homolog B [Homo sapiens]
          Length = 207

 Score = 40.0 bits (92), Expect = 0.018
 Identities = 32/90 (35%), Positives = 47/90 (52%), Gaps = 13/90 (14%)

Query: 70  GFHI----SESLPLTVVAVTAGGSA--HGKLFPGDQILQMNNEPAEDLSWERAVDILREA 123
           GF+I     ++ P+ +  V  GG A  HG L  GDQ+L +N    E    E+AV++L+ A
Sbjct: 104 GFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAA 163

Query: 124 EDSLSITVVRCTSGVPKSSFLTEEKRARLK 153
           + S+ + VVR T  V       EE  AR +
Sbjct: 164 QGSVKL-VVRYTPRV------LEEMEARFE 186


>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
          Length = 1109

 Score = 39.7 bits (91), Expect = 0.023
 Identities = 21/86 (24%), Positives = 41/86 (47%), Gaps = 5/86 (5%)

Query: 69  YGFHIS----ESLPLTVVAVTAGGSAHGK-LFPGDQILQMNNEPAEDLSWERAVDILREA 123
           +GF +     +  PL V  +     A G  L  GD+++ +N  P  DL++   + ++   
Sbjct: 17  WGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESI 76

Query: 124 EDSLSITVVRCTSGVPKSSFLTEEKR 149
            DSL + + R +SG+ ++     E +
Sbjct: 77  TDSLQMLIKRPSSGISEALISENENK 102


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,807,954
Number of Sequences: 37866
Number of extensions: 3481090
Number of successful extensions: 13971
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 250
Number of HSP's that attempted gapping in prelim test: 12800
Number of HSP's gapped (non-prelim): 1410
length of query: 1578
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1462
effective length of database: 13,855,062
effective search space: 20256100644
effective search space used: 20256100644
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.