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Search of human proteins with 238624147
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238624147 neuroplastin isoform c precursor [Homo sapiens]
(394 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238624147 neuroplastin isoform c precursor [Homo sapiens] 800 0.0
gi|6912646 neuroplastin isoform b precursor [Homo sapiens] 794 0.0
gi|238624149 neuroplastin isoform d precursor [Homo sapiens] 508 e-144
gi|9257240 neuroplastin isoform a precursor [Homo sapiens] 503 e-142
gi|38372919 basigin isoform 1 precursor [Homo sapiens] 293 1e-79
gi|38372925 basigin isoform 2 precursor [Homo sapiens] 170 2e-42
gi|38372923 basigin isoform 4 [Homo sapiens] 155 8e-38
gi|110349719 titin isoform N2-A [Homo sapiens] 89 7e-18
gi|109150416 peroxidasin [Homo sapiens] 87 2e-17
gi|7657359 contactin 5 isoform long [Homo sapiens] 76 6e-14
gi|28373129 contactin 5 isoform short [Homo sapiens] 76 6e-14
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 70 3e-12
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 70 3e-12
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 70 3e-12
gi|118572606 hemicentin 1 [Homo sapiens] 70 3e-12
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 70 4e-12
gi|126517478 peroxidasin homolog-like [Homo sapiens] 67 2e-11
gi|38348215 embigin [Homo sapiens] 67 3e-11
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 65 8e-11
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 65 8e-11
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 65 1e-10
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 65 1e-10
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 65 1e-10
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 64 2e-10
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 64 2e-10
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 64 3e-10
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 64 3e-10
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 63 5e-10
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 63 5e-10
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 60 3e-09
>gi|238624147 neuroplastin isoform c precursor [Homo sapiens]
Length = 394
Score = 800 bits (2065), Expect = 0.0
Identities = 394/394 (100%), Positives = 394/394 (100%)
Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTP 60
MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTP
Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTP 60
Query: 61 EIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASN 120
EIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASN
Sbjct: 61 EIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASN 120
Query: 121 DPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLT 180
DPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLT
Sbjct: 121 DPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLT 180
Query: 181 YSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDI 240
YSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDI
Sbjct: 181 YSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDI 240
Query: 241 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 300
TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL
Sbjct: 241 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 300
Query: 301 NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVY 360
NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVY
Sbjct: 301 NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVY 360
Query: 361 EKRKRPDEVPDAGPMKTNSTNNHKDKNLRQRNTN 394
EKRKRPDEVPDAGPMKTNSTNNHKDKNLRQRNTN
Sbjct: 361 EKRKRPDEVPDAGPMKTNSTNNHKDKNLRQRNTN 394
>gi|6912646 neuroplastin isoform b precursor [Homo sapiens]
Length = 398
Score = 794 bits (2050), Expect = 0.0
Identities = 394/398 (98%), Positives = 394/398 (98%), Gaps = 4/398 (1%)
Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTP 60
MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTP
Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTP 60
Query: 61 EIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASN 120
EIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASN
Sbjct: 61 EIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASN 120
Query: 121 DPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLT 180
DPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLT
Sbjct: 121 DPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLT 180
Query: 181 YSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDI 240
YSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDI
Sbjct: 181 YSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDI 240
Query: 241 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 300
TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL
Sbjct: 241 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTEL 300
Query: 301 NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVY 360
NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVY
Sbjct: 301 NIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVY 360
Query: 361 EKRKRPDEVPD----AGPMKTNSTNNHKDKNLRQRNTN 394
EKRKRPDEVPD AGPMKTNSTNNHKDKNLRQRNTN
Sbjct: 361 EKRKRPDEVPDDDEPAGPMKTNSTNNHKDKNLRQRNTN 398
>gi|238624149 neuroplastin isoform d precursor [Homo sapiens]
Length = 278
Score = 508 bits (1309), Expect = e-144
Identities = 247/248 (99%), Positives = 248/248 (100%)
Query: 147 KPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 206
+PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN
Sbjct: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90
Query: 207 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH
Sbjct: 91 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 150
Query: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS
Sbjct: 151 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210
Query: 327 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDAGPMKTNSTNNHKDK 386
VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDAGPMKTNSTNNHKDK
Sbjct: 211 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDAGPMKTNSTNNHKDK 270
Query: 387 NLRQRNTN 394
NLRQRNTN
Sbjct: 271 NLRQRNTN 278
Score = 66.2 bits (160), Expect = 5e-11
Identities = 76/235 (32%), Positives = 96/235 (40%), Gaps = 52/235 (22%)
Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDA----FELYCDVVG 56
MSGSSLPSALALSLLLVSGSLLPGPGAAQN + + SE + D+ L C++
Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVT--SEEVIIRDSPVLPVTLQCNLTS 58
Query: 57 SPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYEC 116
S + + + Y N E + R+ N Y RI + EDSG Y C
Sbjct: 59 S-SHTLTYSYWTKNGVEL-------SATRKNASNMEY--------RINKPRAEDSGEYHC 102
Query: 117 --RASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTS 174
+ PK N ATI V P I T + + T+ C
Sbjct: 103 VYHFVSAPKAN--------------ATIEVKAAPDI-TGHKRSENKNEGQDATMYCKSVG 147
Query: 175 SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPR-----------AEDSGEYHC 218
H +NG+ + N S + INK ED GEY C
Sbjct: 148 YPHPDWIWRKKENGMPMDIV--NTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200
Score = 30.4 bits (67), Expect = 2.9
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 39 SETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGV 98
SE K G +YC VG P P+ W E + + + + + Y +
Sbjct: 130 SENKNEGQDATMYCKSVGYPHPDWIWRKKENGMP---MDIVNTSGRFFIINKENYTELNI 186
Query: 99 SVLRITRLTLEDSGTYECRASN 120
L+IT ED G YEC A+N
Sbjct: 187 VNLQIT----EDPGEYECNATN 204
>gi|9257240 neuroplastin isoform a precursor [Homo sapiens]
Length = 282
Score = 503 bits (1294), Expect = e-142
Identities = 247/252 (98%), Positives = 248/252 (98%), Gaps = 4/252 (1%)
Query: 147 KPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 206
+PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN
Sbjct: 31 EPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 90
Query: 207 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH
Sbjct: 91 KPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 150
Query: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS
Sbjct: 151 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 210
Query: 327 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPD----AGPMKTNSTNN 382
VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPD AGPMKTNSTNN
Sbjct: 211 VVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPDDDEPAGPMKTNSTNN 270
Query: 383 HKDKNLRQRNTN 394
HKDKNLRQRNTN
Sbjct: 271 HKDKNLRQRNTN 282
Score = 66.2 bits (160), Expect = 5e-11
Identities = 76/235 (32%), Positives = 96/235 (40%), Gaps = 52/235 (22%)
Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDA----FELYCDVVG 56
MSGSSLPSALALSLLLVSGSLLPGPGAAQN + + SE + D+ L C++
Sbjct: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNEPRIVT--SEEVIIRDSPVLPVTLQCNLTS 58
Query: 57 SPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYEC 116
S + + + Y N E + R+ N Y RI + EDSG Y C
Sbjct: 59 S-SHTLTYSYWTKNGVEL-------SATRKNASNMEY--------RINKPRAEDSGEYHC 102
Query: 117 --RASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTS 174
+ PK N ATI V P I T + + T+ C
Sbjct: 103 VYHFVSAPKAN--------------ATIEVKAAPDI-TGHKRSENKNEGQDATMYCKSVG 147
Query: 175 SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPR-----------AEDSGEYHC 218
H +NG+ + N S + INK ED GEY C
Sbjct: 148 YPHPDWIWRKKENGMPMDIV--NTSGRFFIINKENYTELNIVNLQITEDPGEYEC 200
Score = 30.4 bits (67), Expect = 2.9
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 7/82 (8%)
Query: 39 SETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGV 98
SE K G +YC VG P P+ W E + + + + + Y +
Sbjct: 130 SENKNEGQDATMYCKSVGYPHPDWIWRKKENGMP---MDIVNTSGRFFIINKENYTELNI 186
Query: 99 SVLRITRLTLEDSGTYECRASN 120
L+IT ED G YEC A+N
Sbjct: 187 VNLQIT----EDPGEYECNATN 204
>gi|38372919 basigin isoform 1 precursor [Homo sapiens]
Length = 385
Score = 293 bits (751), Expect = 1e-79
Identities = 160/392 (40%), Positives = 234/392 (59%), Gaps = 17/392 (4%)
Query: 11 ALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVN 70
A +L+ +LL GA+ AGFV++P+S+ + G + EL+C+ VGSP PEIQWW+
Sbjct: 3 AALFVLLGFALLGTHGASGAAGFVQAPLSQQRWVGGSVELHCEAVGSPVPEIQWWFEGQG 62
Query: 71 RAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQN 130
++ QLWDGAR RV ++ Y + S + I L ED+GTYECRASNDP RN L +
Sbjct: 63 PNDTCSQLWDGARLDRVHIHATYHQHAASTISIDTLVEEDTGTYECRASNDPDRNHLTRA 122
Query: 131 PSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVE 190
P + W+RAQA + VL+ + T+ E + S +L L C+L S+ +T W K GV
Sbjct: 123 PRVKWVRAQAVVLVLEPGTVFTTVEDL--GSKIL---LTCSLNDSATEVTGHRWLKGGVV 177
Query: 191 LSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKN 250
L E++++ + GEY CV F+ P A I++ P + K SE+ N
Sbjct: 178 LKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPEPMGTANIQLHGPPRVKAVKSSEHIN 233
Query: 251 EGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVNTS-GRFFIINKENYTELNIVNLQIT 308
EG+ A + CKS P DW W K + ++N S RFF+ + + +EL+I NL +
Sbjct: 234 EGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNME 293
Query: 309 EDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDE 368
DPG+Y CN T++ GS + LRVRSHLA LWPFLGI+AE+++LV II +YEKR++P++
Sbjct: 294 ADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPED 353
Query: 369 VPD-----AGPMKTNSTN-NHKDKNLRQRNTN 394
V D + P+K++ + N K KN+RQRN++
Sbjct: 354 VLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 385
>gi|38372925 basigin isoform 2 precursor [Homo sapiens]
Length = 269
Score = 170 bits (430), Expect = 2e-42
Identities = 93/237 (39%), Positives = 139/237 (58%), Gaps = 12/237 (5%)
Query: 166 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSA 225
+ L C+L S+ +T W K GV L E++++ + GEY CV F+
Sbjct: 37 ILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSD--DQWGEYSCV--FLPE 92
Query: 226 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWRKKENGMPMDIVN 284
P A I++ P + K SE+ NEG+ A + CKS P DW W K + ++N
Sbjct: 93 PMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMN 152
Query: 285 TS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPF 343
S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + LRVRSHLA LWPF
Sbjct: 153 GSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSHLAALWPF 212
Query: 344 LGILAEIIILVVIIVVYEKRKRPDEVPD-----AGPMKTNSTN-NHKDKNLRQRNTN 394
LGI+AE+++LV II +YEKR++P++V D + P+K++ + N K KN+RQRN++
Sbjct: 213 LGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKGKNVRQRNSS 269
>gi|38372923 basigin isoform 4 [Homo sapiens]
Length = 205
Score = 155 bits (391), Expect = 8e-38
Identities = 82/189 (43%), Positives = 119/189 (62%), Gaps = 10/189 (5%)
Query: 214 GEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH-PDWIWR 272
GEY CV F+ P A I++ P + K SE+ NEG+ A + CKS P DW W
Sbjct: 19 GEYSCV--FLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWY 76
Query: 273 KKENGMPMDIVNTS-GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 331
K + ++N S RFF+ + + +EL+I NL + DPG+Y CN T++ GS + L
Sbjct: 77 KITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITL 136
Query: 332 RVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVPD-----AGPMKTNSTN-NHKD 385
RVRSHLA LWPFLGI+AE+++LV II +YEKR++P++V D + P+K++ + N K
Sbjct: 137 RVRSHLAALWPFLGIVAEVLVLVTIIFIYEKRRKPEDVLDDDDAGSAPLKSSGQHQNDKG 196
Query: 386 KNLRQRNTN 394
KN+RQRN++
Sbjct: 197 KNVRQRNSS 205
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 89.0 bits (219), Expect = 7e-18
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 44/297 (14%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTV-NTAYGS 95
P+S + G++ + C V G+ I W ++ +++ G V NT +
Sbjct: 6277 PVSIDVIAGESADFECHVTGAQPMRITW-------SKDNKEIRPGGNYTITCVGNTPH-- 6327
Query: 96 NGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEE 155
LRI ++ DSG Y C+A+ND ++ A +SV + P+ V E
Sbjct: 6328 -----LRILKVGKGDSGQYTCQATNDVGKD-----------MCSAQLSVKEPPKFVKKLE 6371
Query: 156 VIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEY-------RINKP 208
+ L+C ++ S W +N EL + K NM + IN+
Sbjct: 6372 ASKVAKQGESIQLECKISGSPEIKVS--WFRNDSELHESWKY--NMSFINSVALLTINEA 6427
Query: 209 RAEDSGEYHCVYHF-VSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHP 267
AEDSG+Y C H V + + VKA P T +G D + C+ G P
Sbjct: 6428 SAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPF 6487
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 324
+ +W K V S +F I +K T L+I+NL+ + D GEY C ATN +GS
Sbjct: 6488 EVVWVKDRKQ-----VRNSKKFKITSKHFDTSLHILNLEAS-DVGEYHCKATNEVGS 6538
Score = 73.9 bits (180), Expect = 2e-13
Identities = 78/310 (25%), Positives = 125/310 (40%), Gaps = 42/310 (13%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F+ P S T G A + C V G+P E W DGA
Sbjct: 3553 FLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQK-------------DGAALSPSPNWRI 3599
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
+ +L ++ LT++D G Y C+ASN + I QA + ++ KP +
Sbjct: 3600 SDAENKHILELSNLTIQDRGVYSCKASN-------KFGADI----CQAELIIIDKPHFIK 3648
Query: 153 SEEVIIRDSPVLPVTLQCNLTSSSH-TLTYSYWTKNGVELSATRKNASNMEYRINK---- 207
E ++ + V L+C + T+T W+K+G +L + E +I
Sbjct: 3649 ELEP-VQSAINKKVHLECQVDEDRKVTVT---WSKDGQKLPPGKDYKICFEDKIATLEIP 3704
Query: 208 -PRAEDSGEYHC-VYHFVSAPKANATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVGY 264
+ +DSG Y C + + +AT+ V+ P + S G+ A ++CK G
Sbjct: 3705 LAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGS 3764
Query: 265 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 324
P W K N + NT R + +N E ++ V + ED G Y C A N +GS
Sbjct: 3765 PVIQVTWFK--NNKELSESNTV-RMYFVNSEAILDITDVKV---EDSGSYSCEAVNDVGS 3818
Query: 325 ASVVTVLRVR 334
S T + ++
Sbjct: 3819 DSCSTEIVIK 3828
Score = 67.4 bits (163), Expect = 2e-11
Identities = 75/313 (23%), Positives = 126/313 (40%), Gaps = 46/313 (14%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTV-NT 91
F P+S G++ C V G+ +I W A+ R++ G + V NT
Sbjct: 7214 FDLKPVSVDLALGESGTFKCHVTGTAPIKITW-------AKDNREIRPGGNYKMTLVENT 7266
Query: 92 AYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV 151
A L + ++ D+G Y C ASN ++ + I L+ RIV
Sbjct: 7267 A-------TLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ--EPPRFIKKLEPSRIV 7317
Query: 152 TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME-----YRIN 206
+E +C + S W K+ E+ + K + ++
Sbjct: 7318 KQDEF---------TRYECKIGGSPEIKVL--WYKDETEIQESSKFRMSFVDSVAVLEMH 7366
Query: 207 KPRAEDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 265
EDSG+Y C H + +++T ++VK P +G D + C+ G P
Sbjct: 7367 NLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTP 7426
Query: 266 --HPDWIWRKKENGMPMDIVNTSGRFFIINKENY-TELNIVNLQITEDPGEYECNATNAI 322
H W K+E SG+ + I EN+ T ++I+N+ D GEY+C ATN +
Sbjct: 7427 PFHVSWYKDKREL--------RSGKKYKIMSENFLTSIHILNVDAA-DIGEYQCKATNDV 7477
Query: 323 GSASVVTVLRVRS 335
GS + V + +++
Sbjct: 7478 GSDTCVGSIALKA 7490
Score = 63.5 bits (153), Expect = 3e-10
Identities = 73/311 (23%), Positives = 119/311 (38%), Gaps = 41/311 (13%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
FVK + + G +L + G+ + W+ + +W +
Sbjct: 7494 FVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIW-----------IS 7542
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
Y N ++ L+ +R+ ++G Y C+ ND + AT+SVL+ IV
Sbjct: 7543 YSEN-IATLQFSRVEPANAGKYTCQIKNDAGMQE-----------CFATLSVLEPATIVE 7590
Query: 153 SEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRA-- 210
E I + + TL+C + + T W K+G EL++ K + +++ +
Sbjct: 7591 KPESI-KVTTGDTCTLECTVAGTPELSTK--WFKDGKELTSDNKYKISFFNKVSGLKIIN 7647
Query: 211 ---EDSGEYHC-VYHFVSAPKANATIEVK---AAPDITGHKRSENKNEGQDATMYCKSVG 263
DSG Y V + V A+++V P T + N G M CK G
Sbjct: 7648 VAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYG 7707
Query: 264 YPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 323
P W + N + +SGR + + T VN+ D G+Y C ATN G
Sbjct: 7708 SPPISVSWFHEGNEI------SSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAG 7761
Query: 324 SASVVTVLRVR 334
S L VR
Sbjct: 7762 SDECSAPLTVR 7772
Score = 60.1 bits (144), Expect = 3e-09
Identities = 70/322 (21%), Positives = 124/322 (38%), Gaps = 51/322 (15%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
FVK GD+ L C + G+P + W+ + + R T
Sbjct: 7963 FVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDT-------------KLRPTTTYKM 8009
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQK--PRI 150
+ N V+ L ++ + DSG Y C+A N S+ + A ++V ++ P
Sbjct: 8010 HFRNNVATLVFNQVDINDSGEYICKAEN-----------SVGEVSASTFLTVQEQKLPPS 8058
Query: 151 VTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME-------- 202
+ + ++++ LPV C + S S ++ S W K+G L K++ N++
Sbjct: 8059 FSRQLRDVQETVGLPVVFDCAI-SGSEPISVS-WYKDGKPL----KDSPNVQTSFLDNTA 8112
Query: 203 -YRINKPRAEDSGEYHCVY-HFVSAPKANATI---EVKAAPDITGHKRSENKNEGQDATM 257
I K +G+Y C + + + ++A + E K P + G+ A
Sbjct: 8113 TLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADF 8172
Query: 258 YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECN 317
C G W K + + G++ I EN L ++ + D G+Y C
Sbjct: 8173 ECHVTGTQPIKVSWAKDSRE-----IRSGGKYQISYLENSAHLTVLKVD-KGDSGQYTCY 8226
Query: 318 ATNAIGSASVVTVLRVRSHLAP 339
A N +G S L ++ L P
Sbjct: 8227 AVNEVGKDSCTAQLNIKERLIP 8248
Score = 58.2 bits (139), Expect = 1e-08
Identities = 74/322 (22%), Positives = 127/322 (39%), Gaps = 59/322 (18%)
Query: 33 FVKSPM--------SETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARK 84
FVK P S+ GDA +L C V G+P +I W+ + R++ + ++
Sbjct: 4294 FVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFAND-------REIKESSKH 4346
Query: 85 RRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRND------LRQNPSITWIRA 138
R V + +VLR+T + +EDSG Y C A N+ + ++++P T +
Sbjct: 4347 RMSFVEST------AVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFT--KE 4398
Query: 139 QATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA 198
I VL++ ++ EV +P +T W K+ L + RK
Sbjct: 4399 FKPIEVLKEYDVMLLAEV--AGTPPFEIT----------------WFKDNTILRSGRKYK 4440
Query: 199 SNME-----YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEG 252
+ ++ +I K A D+GEY C V + V + +A + ++ P S + G
Sbjct: 4441 TFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRG 4500
Query: 253 QDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPG 312
A G W K D + + + N L + +++ D G
Sbjct: 4501 GTAAFQATLKGSLPITVTWLKDS-----DEITEDDNIRMTFENNVASLYLSGIEVKHD-G 4554
Query: 313 EYECNATNAIGSASVVTVLRVR 334
+Y C A N G +L V+
Sbjct: 4555 KYVCQAKNDAGIQRCSALLSVK 4576
Score = 58.2 bits (139), Expect = 1e-08
Identities = 72/302 (23%), Positives = 106/302 (35%), Gaps = 45/302 (14%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
GD+ L C V G+P + W+ + + R Y +N V+ L
Sbjct: 6093 GDSVSLQCQVAGTPEITVSWYKGDT-------------KLRPTPEYRTYFTNNVATLVFN 6139
Query: 105 RLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVL 164
++ + DSG Y C+A N + S T R Q Q P + I + L
Sbjct: 6140 KVNINDSGEYTCKAENS-----IGTASSKTVFRIQER----QLPPSFARQLKDIEQTVGL 6190
Query: 165 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNM-----EYRINKPRAEDSGEYHCV 219
PVTL C L S+ W ++GV L ++ +I + SG+Y C
Sbjct: 6191 PVTLTCRLNGSAPIQV--CWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSC- 6247
Query: 220 YHFVSAPKANATI-------EVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 272
S P A+ E K +P S + G+ A C G W
Sbjct: 6248 --SASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWS 6305
Query: 273 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 332
K + G + I N L I+ + D G+Y C ATN +G L
Sbjct: 6306 KDNKE-----IRPGGNYTITCVGNTPHLRILKVG-KGDSGQYTCQATNDVGKDMCSAQLS 6359
Query: 333 VR 334
V+
Sbjct: 6360 VK 6361
Score = 56.6 bits (135), Expect = 4e-08
Identities = 64/309 (20%), Positives = 123/309 (39%), Gaps = 40/309 (12%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F+ P + + E + G+P +I+W+ +V +L G +
Sbjct: 5332 FLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDV-------ELVSGPK-------CF 5377
Query: 93 YGSNG-VSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV 151
G G S L + + +G Y C +ND + +T + L+ +IV
Sbjct: 5378 IGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVT--EPPKFVKKLEASKIV 5435
Query: 152 TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA-----SNMEYRIN 206
+ + L+C + S W +N EL A+ K S ++N
Sbjct: 5436 KAGD---------SSRLECKIAGSPEIRVV--WFRNEHELPASDKYRMTFIDSVAVIQMN 5484
Query: 207 KPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 265
EDSG++ C + + + + VK P + + + ++ C+ G P
Sbjct: 5485 NLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTP 5544
Query: 266 HPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
+ +W K + + +S ++ I +K +T ++I+N+ T D GEY C A N +GS
Sbjct: 5545 PFEVVWYKDKRQL-----RSSKKYKIASKNFHTSIHILNVD-TSDIGEYHCKAQNEVGSD 5598
Query: 326 SVVTVLRVR 334
+ V ++++
Sbjct: 5599 TCVCTVKLK 5607
Score = 56.2 bits (134), Expect = 5e-08
Identities = 81/314 (25%), Positives = 125/314 (39%), Gaps = 50/314 (15%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVN 90
F K + G +L C V GS IQW+ E++ +E ++ + N
Sbjct: 4677 FTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHD--------N 4728
Query: 91 TAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI 150
TA+ L I++L DSGTY C A+N N + ++V + P
Sbjct: 4729 TAF-------LEISQLEGTDSGTYTCSATNKAGHN-----------QCSGHLTVKEPPYF 4770
Query: 151 V---TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVEL--SATR---KNASNME 202
V S++V +P V L+ L + +T W K+ EL A R K+ ++
Sbjct: 4771 VEKPQSQDV----NPNTRVQLKA-LVGGTAPMTIK-WFKDNKELHSGAARSVWKDDTSTS 4824
Query: 203 YRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPD-ITGHKRSENKNEGQDATMYCK 260
+ +A DSG Y C + + V + AT+ VK P I GQ T C+
Sbjct: 4825 LELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQ 4884
Query: 261 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 320
G P W +G + + G FI + I ++ E+ G Y C A N
Sbjct: 4885 ITGTPKIRVSWYL--DGNEITAIQKHGISFI---DGLATFQISGARV-ENSGTYVCEARN 4938
Query: 321 AIGSASVVTVLRVR 334
G+AS L+V+
Sbjct: 4939 DAGTASCSIELKVK 4952
Score = 54.7 bits (130), Expect = 1e-07
Identities = 73/315 (23%), Positives = 118/315 (37%), Gaps = 44/315 (13%)
Query: 31 AGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVN 90
A V+ P S TGD L C V G+P +W+ DG + +T +
Sbjct: 7586 ATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFK-------------DG---KELTSD 7629
Query: 91 TAYG---SNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQK 147
Y N VS L+I + DSG Y N ++ A +S
Sbjct: 7630 NKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDS---------CTASLQVSDRTV 7680
Query: 148 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNM-----E 202
P T + V ++C + S ++ S W G E+S+ RK + +
Sbjct: 7681 PPSFTRKLKETNGLSGSSVVMECKVYGSP-PISVS-WFHEGNEISSGRKYQTTLTDNTCA 7738
Query: 203 YRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKS 261
+N DSG+Y C+ + + + +A + V+ P + G + T
Sbjct: 7739 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIV 7798
Query: 262 VGYPHPDWIWRKKENGM-PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 320
G P W K + + P D N S +++ EL + ++ T GEY C +N
Sbjct: 7799 KGTPPFSVSWFKGSSELVPGDRCNVS------LEDSVAELELFDVD-TSQSGEYTCIVSN 7851
Query: 321 AIGSASVVTVLRVRS 335
G AS T L +++
Sbjct: 7852 EAGKASCTTHLYIKA 7866
Score = 54.3 bits (129), Expect = 2e-07
Identities = 74/302 (24%), Positives = 119/302 (39%), Gaps = 47/302 (15%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA--YGSNGVSV 100
L G++ L+C + GSP ++ W+ +ES NT Y N ++
Sbjct: 3750 LPGESARLHCKLKGSPVIQVTWFKNNKELSES---------------NTVRMYFVNSEAI 3794
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEV--II 158
L IT + +EDSG+Y C A ND + I + + P + + E I+
Sbjct: 3795 LDITDVKVEDSGSYSCEAVNDVGSDS-----------CSTEIVIKEPPSFIKTLEPADIV 3843
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRK-----NASNMEYRINKPRAEDS 213
R + L LQC + S + S W K+ ++ +++K S + I + D
Sbjct: 3844 RGTNAL---LQCEV-SGTGPFEIS-WFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADV 3898
Query: 214 GEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 272
GEY CV + V AT +K P GQ T+ G W
Sbjct: 3899 GEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWM 3958
Query: 273 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 332
K + +++ G+ + L I ++QI+ G+Y C A N GS + V L
Sbjct: 3959 KGQ-----EVIREDGKIKMSFSNGVAVLIIPDVQISFG-GKYTCLAENEAGSQTSVGELI 4012
Query: 333 VR 334
V+
Sbjct: 4013 VK 4014
Score = 53.9 bits (128), Expect = 2e-07
Identities = 77/317 (24%), Positives = 123/317 (38%), Gaps = 50/317 (15%)
Query: 31 AGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVN 90
A ++ P T TG+ F L C V G+P +W+ + R+L K +T
Sbjct: 6645 ARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWF-------KDGREL-SADSKHHITF- 6695
Query: 91 TAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI 150
N V+ L+I + D G Y N +++ T+SV RI
Sbjct: 6696 ----INKVASLKIPCAEMSDKGLYSFEVKNSVGKSN-------------CTVSVHVSDRI 6738
Query: 151 VTSEEV-IIRDSPVL---PVTLQCNLTSSSHTLTYSYWTKNGVEL-------SATRKNAS 199
V + ++D + V L+C ++ S+ W ++G E+ S+ +N
Sbjct: 6739 VPPSFIRKLKDVNAILGASVVLECRVSGSAPISV--GWFQDGNEIVSGPKCQSSFSENVC 6796
Query: 200 NMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMY 258
+ + +P D+G Y CV + + + +A + V+ P S G T
Sbjct: 6797 TLNLSLLEP--SDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFT 6854
Query: 259 CKSVGYPHPDWIWRKKENGM-PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECN 317
G P W K + P + N S F+ TEL + +Q E G+Y C
Sbjct: 6855 SVIRGTPPFKVKWFKGSRELVPGESCNISLEDFV------TELELFEVQPLES-GDYSCL 6907
Query: 318 ATNAIGSASVVTVLRVR 334
TN GSAS T L V+
Sbjct: 6908 VTNDAGSASCTTHLFVK 6924
Score = 53.5 bits (127), Expect = 3e-07
Identities = 72/319 (22%), Positives = 125/319 (39%), Gaps = 48/319 (15%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F+ P S+ G C++ G P+PEI+W F+ + V+++
Sbjct: 33136 FISQPRSQNINEGQNVLFTCEISGEPSPEIEW----------FKNNLPISISSNVSISR- 33184
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQ--ATISVLQKPRI 150
S V L I ++ DSG Y +A N R Q AT S++ P +
Sbjct: 33185 --SRNVYSLEIRNASVSDSGKYTIKAKN---------------FRGQCSATASLMVLPLV 33227
Query: 151 -VTSEEVIIRDSPVLPV-----TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYR 204
S EV++R S + + +++S ++S ++ + K AS
Sbjct: 33228 EEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQS 33287
Query: 205 INKPR---AEDSGEYHCVYHFVSAPKANATIEVKAA-----PDITGHKRSENKNEGQDAT 256
++ + E S ++ +++ + +KA P I + +EG+ T
Sbjct: 33288 MSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLT 33347
Query: 257 MYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 316
+ C G P P+ W G GRF I N ++ T L I+++Q +D G Y
Sbjct: 33348 VACAFTGEPTPEVTW---SCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ-KQDGGLYTL 33403
Query: 317 NATNAIGSASVVTVLRVRS 335
+ N GS S + +RS
Sbjct: 33404 SLGNEFGSDSATVNIHIRS 33422
Score = 53.1 bits (126), Expect = 4e-07
Identities = 70/310 (22%), Positives = 115/310 (37%), Gaps = 48/310 (15%)
Query: 35 KSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYG 94
K S+ G++ +L C + GSP ++ W+ + ES++ N ++
Sbjct: 6369 KLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWK------------YNMSF- 6415
Query: 95 SNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSE 154
N V++L I + EDSG Y C A N + T + +A QKP V +
Sbjct: 6416 INSVALLTINEASAEDSGDYICEA-----HNGVGDASCSTALTVKAPPVFTQKPSPVGA- 6469
Query: 155 EVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTK------NGVELSATRKNASNMEYRINKP 208
++ S V+ LQC ++ + W K N + T K+ + +N
Sbjct: 6470 ---LKGSDVI---LQCEISGTPPFEV--VWVKDRKQVRNSKKFKITSKHFDTSLHILNL- 6520
Query: 209 RAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHP 267
A D GEYHC + V + + +++ K P + G + G+
Sbjct: 6521 EASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPI 6580
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQI----TEDPGEYECNATNAIG 323
+W K + + NT F NI LQ+ + G+Y C N G
Sbjct: 6581 SVVWLKDRGEVIRESENTRISFID---------NIATLQLGSPEASNSGKYICQIKNDAG 6631
Query: 324 SASVVTVLRV 333
VL V
Sbjct: 6632 MRECSAVLTV 6641
Score = 53.1 bits (126), Expect = 4e-07
Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 16/160 (10%)
Query: 184 WTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATI--E 233
W NGVEL+ + + + S+ I + D G C+ + + + T+ E
Sbjct: 33070 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE 33129
Query: 234 VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIIN 293
+ AP RS+N NEGQ+ C+ G P P+ W K N +P+ I S I
Sbjct: 33130 LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK--NNLPISI---SSNVSISR 33184
Query: 294 KENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
N L I N ++ D G+Y A N G S L V
Sbjct: 33185 SRNVYSLEIRNASVS-DSGKYTIKAKNFRGQCSATASLMV 33223
Score = 52.0 bits (123), Expect = 9e-07
Identities = 78/334 (23%), Positives = 124/334 (37%), Gaps = 62/334 (18%)
Query: 31 AGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVN 90
A FVK + TG L G+P + W E ++S R ++
Sbjct: 6927 ATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQS----------ERCSIT 6976
Query: 91 TAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI 150
S ++L I T+ED Y C N+ ++ +A +SVL+ P
Sbjct: 6977 MTEKS---TILEILESTIEDYAQYSCLIENEAGQDI-----------CEALVSVLEPPYF 7022
Query: 151 VTS---EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYR--- 204
+ E +I + P TLQC + + W K +L + A M+++
Sbjct: 7023 IEPLEHVEAVIGE----PATLQCKVDGTPEIRIS--WYKEHTKLRSAP--AYKMQFKNNV 7074
Query: 205 ----INKPRAEDSGEYHC-VYHFVSAPKANATIEVKAA---PDITGHKRSENKNEGQDAT 256
INK D GEY C + V A ++A + +KA P + ++ G
Sbjct: 7075 ASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVA 7134
Query: 257 MYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDP----G 312
C+ G W K + + D N F N+ LQI + G
Sbjct: 7135 FECRINGSEPLQVSWYK-DGVLLKDDANLQTSFVH---------NVATLQILQTDQSHIG 7184
Query: 313 EYECNATNAIGSASVVTVLRVRSHLAPLWPFLGI 346
+Y C+A+N +G+AS L + H P PF +
Sbjct: 7185 QYNCSASNPLGTASSSAKLILSEHEVP--PFFDL 7216
Score = 52.0 bits (123), Expect = 9e-07
Identities = 71/318 (22%), Positives = 119/318 (37%), Gaps = 49/318 (15%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
FV+ P LTG V G+P + W+ + +L G R N +
Sbjct: 7777 FVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWF-------KGSSELVPGDR-----CNVS 7824
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQAT-ISVLQKPRIV 151
+ V+ L + + SG Y C SN+ + + +I+A A + L I
Sbjct: 7825 L-EDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTH---LYIKAPAKFVKRLNDYSIE 7880
Query: 152 TSEEVIIRDS----PVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRK-NASNME---- 202
+ +I+ + P + VT W KNG+ ++ +++ N + E
Sbjct: 7881 KGKPLILEGTFTGTPPISVT----------------WKKNGINVTPSQRCNITTTEKSAI 7924
Query: 203 YRINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAAPDITGHKRSENKNEGQDATMYCKS 261
I ED+G+Y+C S + +A I + P + G A++ C+
Sbjct: 7925 LEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQL 7984
Query: 262 VGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNA 321
G P W K + + T+ + N N V++ D GEY C A N+
Sbjct: 7985 AGTPEIGVSWYKGDTKLRP---TTTYKMHFRNNVATLVFNQVDIN---DSGEYICKAENS 8038
Query: 322 IGSASVVTVLRVRSHLAP 339
+G S T L V+ P
Sbjct: 8039 VGEVSASTFLTVQEQKLP 8056
Score = 51.6 bits (122), Expect = 1e-06
Identities = 69/310 (22%), Positives = 112/310 (36%), Gaps = 42/310 (13%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F K + + L C + GS + W+ + +++ R R V
Sbjct: 4115 FTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWF-------KDGKEIAASDRYRIAFVE-- 4165
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
G + L I R+ + D+G + CRA+N D + + V + P VT
Sbjct: 4166 ----GTASLEIIRVDMNDAGNFTCRATNSVGSKD-----------SSGALIVQEPPSFVT 4210
Query: 153 SEEVIIRDSPVLPVTLQC-NLTSSSHTLTYSYWTKNGVELSA-----TRKNASNMEYRIN 206
VLP + C T T W K EL + K A +
Sbjct: 4211 KP----GSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELY 4266
Query: 207 KPRAEDSGEYHC-VYHFVSAPKANATIEVK-AAPDITGHKRSENKNEGQDATMYCKSVGY 264
+ DSG Y C V + + +A + VK A + + S+ +G + CK G
Sbjct: 4267 LVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGT 4326
Query: 265 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 324
P W + + S + + E+ L + ++ I ED GEY C A N GS
Sbjct: 4327 PPIKITWFANDRE-----IKESSKHRMSFVESTAVLRLTDVGI-EDSGEYMCEAQNEAGS 4380
Query: 325 ASVVTVLRVR 334
+++ V+
Sbjct: 4381 DHCSSIVIVK 4390
Score = 51.6 bits (122), Expect = 1e-06
Identities = 68/297 (22%), Positives = 115/297 (38%), Gaps = 42/297 (14%)
Query: 46 DAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITR 105
D L C V G+P +++W L DG + + N V+ RI
Sbjct: 5156 DPMTLECVVAGTPELKVKW-------------LKDGKQIVPSRYFSMSFENNVASFRIQS 5202
Query: 106 LTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLP 165
+ +DSG Y + ND + A + VL + + + + + VL
Sbjct: 5203 VMKQDSGQYTFKVENDFGSSS-----------CDAYLRVLDQNIPPSFTKKLTKMDKVLG 5251
Query: 166 VTLQCNLTSSSHTLTYSYWTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYHCVY 220
++ S + W K+G E+S + K + ++ +N ED+ Y C
Sbjct: 5252 SSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKV 5311
Query: 221 HFVSAPKA-NATIEVKAAPDITGHKRSENKNEGQDATMYCKSV--GYPHPDWIWRKKENG 277
V+ A + + VK P + + D+T+ K++ G P W K
Sbjct: 5312 SNVAGDDACSGILTVKEPPSFL--VKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKD--- 5366
Query: 278 MPMDIVNTSGRFFIINKENYTE-LNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
D+ SG I E T LN+ ++ ++ G+Y C+ TN +GS S T+L V
Sbjct: 5367 ---DVELVSGPKCFIGLEGSTSFLNLYSVDASK-TGQYTCHVTNDVGSDSCTTMLLV 5419
Score = 51.6 bits (122), Expect = 1e-06
Identities = 66/311 (21%), Positives = 116/311 (37%), Gaps = 44/311 (14%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVN 90
F K K+ G + + C V GS QW+ E++ + +R + +R V+
Sbjct: 5239 FTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLV---CHERSVS-- 5293
Query: 91 TAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI 150
L + L LED+ Y C+ SN + ++V + P
Sbjct: 5294 ----------LEVNNLELEDTANYTCKVSNVAGDD-----------ACSGILTVKEPPSF 5332
Query: 151 VTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRK-----NASNMEYRI 205
+ R + T++ W K+ VEL + K S +
Sbjct: 5333 LVKPG---RQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNL 5389
Query: 206 NKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVG 263
A +G+Y C V + V + + V P + + S+ G + + CK G
Sbjct: 5390 YSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAG 5449
Query: 264 YPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 323
P +W + E+ +P S ++ + ++ + + NL TED G++ C A N G
Sbjct: 5450 SPEIRVVWFRNEHELP-----ASDKYRMTFIDSVAVIQMNNLS-TEDSGDFICEAQNPAG 5503
Query: 324 SASVVTVLRVR 334
S S T + V+
Sbjct: 5504 STSCSTKVIVK 5514
Score = 51.6 bits (122), Expect = 1e-06
Identities = 67/313 (21%), Positives = 109/313 (34%), Gaps = 39/313 (12%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
FVK P L G + G+P ++ W+ R+L G R
Sbjct: 5895 FVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWF-------RGARELVKGDRCN------I 5941
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
Y + V+ L + + + SG Y C SN+ + + A + L +
Sbjct: 5942 YFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVK--EPAAFLKRLSDHSVEP 5999
Query: 153 SEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRK-NASNME----YRINK 207
+ +I+ + TL ++T W K+G ++ + K N E I
Sbjct: 6000 GKSIILEST--YTGTLPISVT----------WKKDGFNITTSEKCNIVTTEKTCILEILN 6047
Query: 208 PRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
D+G+Y C + + A + P G ++ C+ G P
Sbjct: 6048 STKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPE 6107
Query: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
W K + + R + N N VN+ D GEY C A N+IG+AS
Sbjct: 6108 ITVSWYKGDTKLRP---TPEYRTYFTNNVATLVFNKVNIN---DSGEYTCKAENSIGTAS 6161
Query: 327 VVTVLRVRSHLAP 339
TV R++ P
Sbjct: 6162 SKTVFRIQERQLP 6174
Score = 51.2 bits (121), Expect = 2e-06
Identities = 62/247 (25%), Positives = 104/247 (42%), Gaps = 24/247 (9%)
Query: 96 NGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEE 155
+ V+ L+I + L SG Y C ASN + +T + + KP S +
Sbjct: 6227 DNVATLKILQTDLSHSGQYSCSASNP--LGTASSSARLTAREPKKSPFFDIKP---VSID 6281
Query: 156 VIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVEL----SATRKNASNMEY-RINKPRA 210
VI +S +C++T + W+K+ E+ + T N + RI K
Sbjct: 6282 VIAGES----ADFECHVTGAQPMRIT--WSKDNKEIRPGGNYTITCVGNTPHLRILKVGK 6335
Query: 211 EDSGEYHC-VYHFVSAPKANATIEVKAAPDITGH-KRSENKNEGQDATMYCKSVGYPHPD 268
DSG+Y C + V +A + VK P + S+ +G+ + CK G P
Sbjct: 6336 GDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIK 6395
Query: 269 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 328
W + ++ + + S ++ + + N L +N ED G+Y C A N +G AS
Sbjct: 6396 VSWFRNDSEL-----HESWKYNM-SFINSVALLTINEASAEDSGDYICEAHNGVGDASCS 6449
Query: 329 TVLRVRS 335
T L V++
Sbjct: 6450 TALTVKA 6456
Score = 50.4 bits (119), Expect = 3e-06
Identities = 67/304 (22%), Positives = 109/304 (35%), Gaps = 52/304 (17%)
Query: 33 FVKSPMSETKL-TGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNT 91
F+K P L G + C + G+P + W+ DG + +
Sbjct: 4863 FIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYL-------------DGNEITAIQKHG 4909
Query: 92 AYGSNGVSVLRITRLTLEDSGTYECRASNDPKRN----DLRQNPSITWIRAQATISVLQK 147
+G++ +I+ +E+SGTY C A ND +L+ T+IR + V++
Sbjct: 4910 ISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKY 4969
Query: 148 PRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRK-----NASNME 202
+ EV +P VT W KN E+ +++K S
Sbjct: 4970 SDVELECEV--TGTPPFEVT----------------WLKNNREIRSSKKYTLTDRVSVFN 5011
Query: 203 YRINKPRAEDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNE--GQDATMYC 259
I K D+GEY C+ + +T + +K P K+ EN AT
Sbjct: 5012 LHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFI--KKIENTTTVLKSSATFQS 5069
Query: 260 KSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 319
G P W K + I++ +I ++ L I ++ G Y C A
Sbjct: 5070 TVAGSPPISITWLKDD-----QILDEDDNVYISFVDSVATLQIRSVD-NGHSGRYTCQAK 5123
Query: 320 NAIG 323
N G
Sbjct: 5124 NESG 5127
Score = 48.5 bits (114), Expect = 1e-05
Identities = 78/313 (24%), Positives = 121/313 (38%), Gaps = 45/313 (14%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
FVK + L GDA EL V G + W +R E R+ + R++
Sbjct: 6553 FVKKLSDTSTLIGDAVELRAIVEGFQPISVVWL---KDRGEVIRE----SENTRISF--- 6602
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
+ ++ L++ +SG Y C+ ND + A ++VL+ RI+
Sbjct: 6603 --IDNIATLQLGSPEASNSGKYICQIKNDAGMRE-----------CSAVLTVLEPARIIE 6649
Query: 153 SEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKN---ASNMEYRINKPR 209
E + + P L+C +T + + W K+G ELSA K+ N + P
Sbjct: 6650 KPEPMTVTTG-NPFALECVVTGTPE--LSAKWFKDGRELSADSKHHITFINKVASLKIPC 6706
Query: 210 AEDSGEYHCVYHFV---SAPKANATIEVKAA-----PDITGHKRSENKNEGQDATMYCKS 261
AE S + +Y F S K+N T+ V + P + N G + C+
Sbjct: 6707 AEMSDK--GLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRV 6764
Query: 262 VGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNA 321
G W + N +IV + + EN LN+ L+ D G Y C A N
Sbjct: 6765 SGSAPISVGWFQDGN----EIV-SGPKCQSSFSENVCTLNLSLLE-PSDTGIYTCVAANV 6818
Query: 322 IGSASVVTVLRVR 334
GS VL V+
Sbjct: 6819 AGSDECSAVLTVQ 6831
Score = 47.8 bits (112), Expect = 2e-05
Identities = 65/279 (23%), Positives = 110/279 (39%), Gaps = 34/279 (12%)
Query: 69 VNRAESFRQLW--DGAR-KRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRN 125
+N +E + W DG K + T++ N V+ L+I + G Y C ASN
Sbjct: 7139 INGSEPLQVSWYKDGVLLKDDANLQTSFVHN-VATLQILQTDQSHIGQYNCSASNPL--- 7194
Query: 126 DLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWT 185
A+ +S + P + V + + T +C++T ++ W
Sbjct: 7195 ------GTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKIT--WA 7246
Query: 186 KNGVEL--------SATRKNASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKA 236
K+ E+ + A+ ++ K D+G+Y C + +A + V+
Sbjct: 7247 KDNREIRPGGNYKMTLVENTATLTVLKVGKG---DAGQYTCYASNIAGKDSCSAQLGVQE 7303
Query: 237 APDITGHKRSENKNEGQDATMY-CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 295
P + + T Y CK G P +W K E + S +F + +
Sbjct: 7304 PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETE-----IQESSKFRMSFVD 7358
Query: 296 NYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
+ L + NL + ED G+Y C A NA GSAS T L+V+
Sbjct: 7359 SVAVLEMHNLSV-EDSGDYTCEAHNAAGSASSSTSLKVK 7396
Score = 46.6 bits (109), Expect = 4e-05
Identities = 66/310 (21%), Positives = 117/310 (37%), Gaps = 42/310 (13%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
PM+ T G+ L C V G+P ++W+ +L ++K + + N
Sbjct: 5712 PMTVT--VGETCTLECKVAGTPELSVEWY--------KDGKLLTSSQKHKFSFY-----N 5756
Query: 97 GVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEV 156
+S LRI + +D+GTY + N+ ++ A + V + +
Sbjct: 5757 KISSLRILSVERQDAGTYTFQVQNNVGKSS-----------CTAVVDVSDRAVPPSFTRR 5805
Query: 157 IIRDSPVLPVT--LQCNLTSSSHTLTYSYWTKNGVELSA---TRKNASNMEYRINKPRAE 211
+ VL + L+C + SS + K + A T + + ++N +
Sbjct: 5806 LKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSS 5865
Query: 212 DSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP--HPD 268
D G Y CV + + + A + V+ P G++ T G P +
Sbjct: 5866 DMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVN 5925
Query: 269 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 328
W +E + R I ++ EL + N+ I++ GEY C +N G AS
Sbjct: 5926 WFRGARE-------LVKGDRCNIYFEDTVAELELFNIDISQS-GEYTCVVSNNAGQASCT 5977
Query: 329 TVLRVRSHLA 338
T L V+ A
Sbjct: 5978 TRLFVKEPAA 5987
Score = 43.1 bits (100), Expect = 4e-04
Identities = 65/297 (21%), Positives = 103/297 (34%), Gaps = 39/297 (13%)
Query: 49 ELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTL 108
EL C+V G+P E+ W L + R T V L IT+
Sbjct: 4973 ELECEVTGTPPFEVTW-------------LKNNREIRSSKKYTLTDRVSVFNLHITKCDP 5019
Query: 109 EDSGTYECRASND------PKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
D+G Y+C SN+ R L++ PS + + T +VL+ T + + P
Sbjct: 5020 SDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIK-KIENTTTVLKSS--ATFQSTVAGSPP 5076
Query: 163 VLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHF 222
+ L+ + Y + + L R + R +SG C Y F
Sbjct: 5077 ISITWLKDDQILDEDDNVYISFVDSVATLQI-RSVDNGHSGRYTCQAKNESGVERC-YAF 5134
Query: 223 VSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDI 282
+ + +E + D+T E T+ C G P W K +
Sbjct: 5135 LLVQEPAQIVEKAKSVDVT---------EKDPMTLECVVAGTPELKVKWLKDGKQI---- 5181
Query: 283 VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 339
R+F ++ EN + + +D G+Y N GS+S LRV P
Sbjct: 5182 --VPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIP 5236
Score = 42.4 bits (98), Expect = 7e-04
Identities = 66/317 (20%), Positives = 119/317 (37%), Gaps = 47/317 (14%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F ++P S L G + + G+P +++W+ + R+L G + N +
Sbjct: 6836 FEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWF-------KGSRELVPGE-----SCNIS 6883
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKR----NDLRQNPSITWIRAQATISVLQKP 148
+ V+ L + + +SG Y C +ND L T+++ A SV
Sbjct: 6884 L-EDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGS 6942
Query: 149 RIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYR---- 204
IV E +P + V+ W K+ +S + + + M +
Sbjct: 6943 PIVL--EATYTGTPPISVS----------------WIKDEYLISQSERCSITMTEKSTIL 6984
Query: 205 -INKPRAEDSGEYHCVYHFVSAPK-ANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 262
I + ED +Y C+ + A + V P G+ AT+ CK
Sbjct: 6985 EILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVD 7044
Query: 263 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 322
G P W K+ + ++ + + K N L ++N D GEY C A N++
Sbjct: 7045 GTPEIRISWYKEHTKL-----RSAPAYKMQFKNNVASL-VINKVDHSDVGEYSCKADNSV 7098
Query: 323 GSASVVTVLRVRSHLAP 339
G+ + VL +++ P
Sbjct: 7099 GAVASSAVLVIKARKLP 7115
Score = 42.4 bits (98), Expect = 7e-04
Identities = 61/249 (24%), Positives = 89/249 (35%), Gaps = 37/249 (14%)
Query: 96 NGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEE 155
N VL++ + + D+G Y C+ SND + I +KP +
Sbjct: 8302 NNTLVLQVRKAGMNDAGLYTCKVSND---------AGSALCTSSIVIKEPKKPPVFDQHL 8352
Query: 156 VIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRK-----NASNMEYRINKPRA 210
+ S V L C++ S W K G E+ + + + +
Sbjct: 8353 TPVTVSEGEYVQLSCHVQGSEPIRI--QWLKAGREIKPSDRCSFSFASGTAVLELRDVAK 8410
Query: 211 EDSGEYHCVYHFVS---APKANATIE---------VKAAPD----ITGHKRSENKNEGQD 254
DSG+Y C V+ K+ TI+ KAA D +S E
Sbjct: 8411 ADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTT 8470
Query: 255 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEY 314
AT K G P P+ W K + +N GR FI K + +L I + T D G Y
Sbjct: 8471 ATFIAKVGGDPIPNVKWTKGK----WRQLNQGGRVFIHQKGDEAKLEIRDTTKT-DSGLY 8525
Query: 315 ECNATNAIG 323
C A N G
Sbjct: 8526 RCVAFNEHG 8534
Score = 42.4 bits (98), Expect = 7e-04
Identities = 64/304 (21%), Positives = 113/304 (37%), Gaps = 55/304 (18%)
Query: 65 WYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKR 124
WY V + E+ + K +T +GV++L + +T D GTY C+ ND
Sbjct: 31602 WYFGVRQLEN-------SEKYEITYE-----DGVAILYVKDITKLDDGTYRCKVVNDYGE 31649
Query: 125 NDLRQNPSITWI----------------RAQATISVLQKPRIVTSEEVIIRDSPVLPVTL 168
+ + + R T+ +L++P T + + + +
Sbjct: 31650 DSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLP--LYNKTAYVGENV 31707
Query: 169 QCNLTSSSHTLTYSYWTKNGVELS--------ATRKNASNMEYRINKPRAEDSGEYHCV- 219
+ +T + H + W K+G ++ + + IN +D EY V
Sbjct: 31708 RFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVA 31767
Query: 220 --YHFVSAPKANATIEVKAAPDITGHK-------RSENKNEGQDATMYCKSVGYPHPDWI 270
+ + KA T+ + P + + + EGQ + G P P
Sbjct: 31768 RNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLK 31827
Query: 271 WRKKENGMPMDIVNTSGRFFIINKE-NYTELNIVNLQITEDPGEYECNATNAIGSASVVT 329
W K +G P+ + II++ +Y L+I + + ED G Y ATN GS S
Sbjct: 31828 WEK--DGQPLSL---GPNIEIIHEGLDYYALHIRD-TLPEDTGYYRVTATNTAGSTSCQA 31881
Query: 330 VLRV 333
L+V
Sbjct: 31882 HLQV 31885
Score = 42.0 bits (97), Expect = 0.001
Identities = 78/363 (21%), Positives = 127/363 (34%), Gaps = 85/363 (23%)
Query: 51 YCDVV-GSPTPEIQWWYAEVNRAESFRQ--LWDGARKRRVTVNTAYGSNGVSVLRITRLT 107
+C V+ G P P+I W+ E + F+ L DG L +
Sbjct: 3258 FCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEY---------------TLLLIEAF 3302
Query: 108 LEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVT 167
ED+ Y C A ND + A ++ V P +V+ ++ + P +
Sbjct: 3303 PEDAAVYTCEAKNDY---------GVATTSASLSVEV---PEVVSPDQEMPVYPPAIITP 3350
Query: 168 LQCNLTSSSHTLTYSY----------WTKNGVELSATR-----KNASNMEYRINKPRAED 212
LQ +TS + W ++ +R + + I + ED
Sbjct: 3351 LQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPED 3410
Query: 213 SGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNE-------------------- 251
G Y V + V + A + ++A P+ H+R E + E
Sbjct: 3411 EGTYTFVASNAVGQVSSTANLSLEA-PESILHERIEQEIEMEMKAAPVIKRKIEPLEVAL 3469
Query: 252 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDP 311
G A C+ P+ + W K + S + I + + + L I+ Q+ D
Sbjct: 3470 GHLAKFTCEIQSAPNVRFQWFKAGRE-----IYESDKCSIRSSKYISSLEILRTQVV-DC 3523
Query: 312 GEYECNATNAIGSASVVTVLRVRSHLAP--------LWPFLGILAEIIILV----VIIVV 359
GEY C A+N GS S L V P L F+G A+ I V VI +
Sbjct: 3524 GEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETI 3583
Query: 360 YEK 362
++K
Sbjct: 3584 WQK 3586
Score = 42.0 bits (97), Expect = 0.001
Identities = 42/167 (25%), Positives = 76/167 (45%), Gaps = 31/167 (18%)
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRD 160
LR+ L+D G Y L P I A A ++V++ ++V +++
Sbjct: 8714 LRVKNCQLKDQGNYR-----------LVCGPHI----ASAKLTVIEPAWERHLQDVTLKE 8758
Query: 161 SPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINK-----PRAEDSGE 215
+T Q ++ + S W +NG L ++ + +E++++K RAED G+
Sbjct: 8759 GQTCTMTCQFSVPNVK-----SEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQ 8813
Query: 216 YHCVYHFVSAPKANATIEVKAAPDITGHKRSEN--KNEGQDATMYCK 260
Y C Y + + +A + ++A P I KR +N +E Q AT C+
Sbjct: 8814 YTCKYEDL---ETSAELRIEAEP-IQFTKRIQNIVVSEHQSATFECE 8856
Score = 40.0 bits (92), Expect = 0.004
Identities = 65/343 (18%), Positives = 122/343 (35%), Gaps = 51/343 (14%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F + P L G L C++ G+P E+ W V + R ++K ++T
Sbjct: 6460 FTQKPSPVGALKGSDVILQCEISGTPPFEVVW----VKDRKQVR----NSKKFKIT---- 6507
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
+ + L I L D G Y C+A+N+ + ++ + PR V
Sbjct: 6508 -SKHFDTSLHILNLEASDVGEYHCKATNEVGSD-----------TCSCSVKFKEPPRFV- 6554
Query: 153 SEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA------SNMEYRIN 206
+ + S ++ ++ W K+ E+ +N + ++
Sbjct: 6555 --KKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLG 6612
Query: 207 KPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 265
P A +SG+Y C + + + +A + V I G + C G P
Sbjct: 6613 SPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTP 6672
Query: 266 HPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELN-IVNLQI----TEDPGEYECNATN 320
W K + D +K + T +N + +L+I D G Y N
Sbjct: 6673 ELSAKWFKDGRELSAD-----------SKHHITFINKVASLKIPCAEMSDKGLYSFEVKN 6721
Query: 321 AIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKR 363
++G ++ + V + P F+ L ++ ++ VV E R
Sbjct: 6722 SVGKSNCTVSVHVSDRIVPP-SFIRKLKDVNAILGASVVLECR 6763
Score = 39.7 bits (91), Expect = 0.005
Identities = 35/124 (28%), Positives = 53/124 (42%), Gaps = 28/124 (22%)
Query: 2 SGSSLPSALALSLL--LVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPT 59
+G S P A+S+ L SG + G K T G+A +L C +VG P
Sbjct: 30511 TGLSRPRRTAMSIKTKLTSG---------EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPL 30561
Query: 60 PEIQWWY--AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECR 117
P+I+W+ E+ ++ ++ DG R +TV T ED G Y C
Sbjct: 30562 PDIKWYRFGKELIQSRKYKMSSDG-RTHTLTVMTE--------------EQEDEGVYTCI 30606
Query: 118 ASND 121
A+N+
Sbjct: 30607 ATNE 30610
Score = 39.7 bits (91), Expect = 0.005
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Query: 184 WTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCVY-HFVSAPKANATIEVKAA 237
W + G EL +RK + + R + ED G Y C+ + V + ++ + ++A
Sbjct: 30566 WYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQAT 30625
Query: 238 PDI-TGHKRSENKNEGQDATM--YCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 294
P G+ E +T+ + +G P P W + ++ S I N
Sbjct: 30626 PQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-----LLQNSENITIENT 30680
Query: 295 ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
E+YT L + N+Q G+Y+ +N G+ + + ++
Sbjct: 30681 EHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 30720
Score = 39.3 bits (90), Expect = 0.006
Identities = 69/326 (21%), Positives = 118/326 (36%), Gaps = 51/326 (15%)
Query: 24 GPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGAR 83
GPG F+ P+ + + G + C V G+P P + W + V +R
Sbjct: 1075 GPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY------ 1128
Query: 84 KRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATIS 143
+V+ N G L I+ +D+G Y N K + + S+ +A
Sbjct: 1129 --KVSYNK---QTGECKLVISMTFADDAGEYTIVVRN--KHGETSASASLL---EEADYE 1178
Query: 144 VLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEY 203
+L K S++ ++ + V + + ++ YS + K + A + +
Sbjct: 1179 LLMK-----SQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1233
Query: 204 RINKPRAEDSGEYH-----------CVYHFVSAPKANATI---EVKAAPDITGHKRSEN- 248
+ + ED E+H Y + E K A DI+ + E+
Sbjct: 1234 VVVRTYVEDQ-EFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESG 1292
Query: 249 -----KN----EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTE 299
KN EG T +CK GYP P W K +G + F+ +
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK--DGKRIKHGERYQMDFLQDGRASLR 1350
Query: 300 LNIVNLQITEDPGEYECNATNAIGSA 325
+ +V + ED G Y A+N G+A
Sbjct: 1351 IPVV---LPEDEGIYTAFASNIKGNA 1373
Score = 38.5 bits (88), Expect = 0.011
Identities = 59/285 (20%), Positives = 106/285 (37%), Gaps = 32/285 (11%)
Query: 53 DVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSG 112
+V PT E++W++ V ES + + ++GV L I +DSG
Sbjct: 32396 NVQSKPTAEVKWYHNGVELQESSKIHYTN-------------TSGVLTLEILDCHTDDSG 32442
Query: 113 TYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNL 172
TY +N + + ++ T Q+ EEV P L T +
Sbjct: 32443 TYRAVCTN--YKGEASDYATLDVTGGDYTTYASQR----RDEEVPRSVFPELTRTEAYAV 32496
Query: 173 TS---SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKAN 229
+S +S S + +++ TR++ S+ E+ + + E + + K
Sbjct: 32497 SSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIK 32556
Query: 230 ATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRF 289
T+ + I RS EG+ A C + G P P W +K +++TS R
Sbjct: 32557 TTLAAR----ILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKG-----QVLSTSARH 32607
Query: 290 FIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
+ + + I ++Q D G Y N+ G L ++
Sbjct: 32608 QVTTTKYKSTFEISSVQ-ASDEGNYSVVVENSEGKQEAEFTLTIQ 32651
Score = 38.1 bits (87), Expect = 0.014
Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 15/110 (13%)
Query: 230 ATIEVKAAPD-ITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK----ENGMPMDIVN 284
A +E+ P + ++ EG+ T+ C GYP P W ++ E+ + I
Sbjct: 934 APVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITF 993
Query: 285 TSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
SG ++ +E + ED G + C+A N G+ S L V+
Sbjct: 994 QSGIARLMIREAF----------AEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033
Score = 38.1 bits (87), Expect = 0.014
Identities = 56/245 (22%), Positives = 99/245 (40%), Gaps = 27/245 (11%)
Query: 98 VSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVI 157
VS+L+I +DSG Y ND R+ +A+ + L P T +
Sbjct: 4633 VSILKIISTEKKDSGEYTFEVQNDVGRSS---------CKARINVLDLIIPPSFTKKLKK 4683
Query: 158 IRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRK-------NASNMEYRINKPRA 210
+ + L+C + + SH ++ W K+ E+SA+ K N + +E I++
Sbjct: 4684 MDSIKGSFIDLEC-IVAGSHPISIQ-WFKDDQEISASEKYKFSFHDNTAFLE--ISQLEG 4739
Query: 211 EDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 269
DSG Y C + + + + VK P +S++ N + VG P
Sbjct: 4740 TDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKA-LVGGTAPMT 4798
Query: 270 IWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 329
I K+N +++ + + T L + + T D G Y C +N +G+A+
Sbjct: 4799 IKWFKDN----KELHSGAARSVWKDDTSTSLELFAAKAT-DSGTYICQLSNDVGTATSKA 4853
Query: 330 VLRVR 334
L V+
Sbjct: 4854 TLFVK 4858
Score = 38.1 bits (87), Expect = 0.014
Identities = 45/189 (23%), Positives = 69/189 (36%), Gaps = 32/189 (16%)
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASND---PKRNDLRQNPSITWIRAQAT-ISVLQKP 148
Y ++G L+I LT D G Y C S + K N + I + + IS +K
Sbjct: 32768 YSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKS 32827
Query: 149 RIVTSEEVIIR-----------DSPVLPVTLQCNLTSSSHTLTY-----------SYWTK 186
T+E + R PV+ LQ SS + + WTK
Sbjct: 32828 DQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTK 32887
Query: 187 NGVELSATRK-----NASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDI 240
+G ++ K + I+K DSG Y C V + + ++ + +KA D
Sbjct: 32888 DGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDT 32947
Query: 241 TGHKRSENK 249
K S K
Sbjct: 32948 EAQKVSTQK 32956
Score = 37.4 bits (85), Expect = 0.024
Identities = 67/311 (21%), Positives = 109/311 (35%), Gaps = 52/311 (16%)
Query: 28 AQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGAR-KRR 86
A +GF + L G +C + G P P+I W+ DG R K
Sbjct: 1288 AVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYK-------------DGKRIKHG 1334
Query: 87 VTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQ 146
+ +G + LRI + ED G Y ASN ++ N + + L
Sbjct: 1335 ERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASN------IKGNAICSGKLYVEPAAPLG 1388
Query: 147 KPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN 206
P + + E + R + P +++ S + +S R + + M
Sbjct: 1389 APTYIPTLEPVSRIRSLSP-----------RSVSRSPIRMSPARMSPARMSPARMSPARM 1437
Query: 207 KP--RAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGY 264
P R E++ E + +E P S EGQ A K VG
Sbjct: 1438 SPGRRLEETDE--------------SQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGR 1483
Query: 265 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 324
P P+ W + D + ++ KE+ T+ I+ D GE+ A N G
Sbjct: 1484 PMPETFWFHDGQQIVNDYTHK-----VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGR 1538
Query: 325 ASVVTVLRVRS 335
+S+ +L V +
Sbjct: 1539 SSISVILTVEA 1549
Score = 37.0 bits (84), Expect = 0.031
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 237 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 296
AP I + G+ A + C+ VG P PD W + + R + ++ +
Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL------IQSRKYKMSSDG 30585
Query: 297 YTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 335
T V + ED G Y C ATN +G + L +++
Sbjct: 30586 RTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA 30624
Score = 35.8 bits (81), Expect = 0.069
Identities = 60/302 (19%), Positives = 115/302 (38%), Gaps = 40/302 (13%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
+ G++ + C V G+ ++ W A+ R++ G + + ++ S ++VL+
Sbjct: 8165 VVGESADFECHVTGTQPIKVSW-------AKDSREIRSGGKYQ---ISYLENSAHLTVLK 8214
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
+ + DSG Y C A N+ ++ +I L P + ++
Sbjct: 8215 VDK---GDSGQYTCYAVNEVGKDSCTAQLNIK--------ERLIPPSFTKRLSETVEETE 8263
Query: 163 VLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRK-----NASNMEYRINKPRAEDSGEYH 217
L+ + + S +T + W KN +E+ T + + ++ K D+G Y
Sbjct: 8264 GNSFKLEGRV-AGSQPITVA-WYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYT 8321
Query: 218 C-VYHFVSAPKANATI---EVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRK 273
C V + + ++I E K P H +EG+ + C G W K
Sbjct: 8322 CKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLK 8381
Query: 274 KENGM-PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 332
+ P D + F + EL V D G+Y C A+N GS + + +
Sbjct: 8382 AGREIKPSDRCS----FSFASGTAVLELRDV---AKADSGDYVCKASNVAGSDTTKSKVT 8434
Query: 333 VR 334
++
Sbjct: 8435 IK 8436
Score = 35.4 bits (80), Expect = 0.090
Identities = 48/220 (21%), Positives = 82/220 (37%), Gaps = 56/220 (25%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
T + G++ L C + G P+P + WY E + ES ++T +G++
Sbjct: 953 TVIEGESVTLECHISGYPSPTVT-WYREDYQIESSIDF-------QITF-----QSGIAR 999
Query: 101 LRITRLTLEDSGTYECRASNDPKRND----LRQNPSITWIRAQATIS---VLQKPRIVTS 153
L I EDSG + C A N+ L S + + ++ ++ R V S
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVES 1059
Query: 154 EEVIIRDS-----------PVLP----------------VTLQCNLTSSSHTLTYSYWTK 186
+V++ D+ P P V C + + + YW K
Sbjct: 1060 RDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQV--GGNPKPHVYWKK 1117
Query: 187 NGVELS-------ATRKNASNMEYRINKPRAEDSGEYHCV 219
+GV L+ + K + I+ A+D+GEY V
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIV 1157
Score = 35.4 bits (80), Expect = 0.090
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 226 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 285
PK++ I+ AP R+ N +AT+ CK G+P P W ++ + D +
Sbjct: 30919 PKSDVPIQ---APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKY 30975
Query: 286 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
+ F K Y +L I ++ +D Y+ ATN GS S L V
Sbjct: 30976 RIQEF---KGGYHQLIIASV-TDDDATVYQVRATNQGGSVSGTASLEV 31019
Score = 34.7 bits (78), Expect = 0.15
Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 33/155 (21%)
Query: 184 WTKNGVELSATRKNASNMEYRIN-------KPRAEDSGEYHCVYHFVSAPK-ANATIEVK 235
W +N + + K+ E +I+ KPR D GEY F++ K A A +E+
Sbjct: 12944 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPR--DQGEYR----FIAKDKEARAKLELA 12997
Query: 236 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTS--------- 286
AAP I + + G+ TM YP + W K+ + ++T+
Sbjct: 12998 AAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRIL 13057
Query: 287 -------GRFFII--NKENYTELNIVNLQITEDPG 312
GR+ I+ NK E +NL++ + PG
Sbjct: 13058 EAKKGDKGRYKIVLQNKHGKAE-GFINLKVIDVPG 13091
Score = 33.9 bits (76), Expect = 0.26
Identities = 31/117 (26%), Positives = 46/117 (39%), Gaps = 22/117 (18%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
T GD L V G P PE+ W + D R RV ++T S+ S
Sbjct: 18212 TVKAGDTIRLEAGVRGKPFPEVAW--------TKDKDATDLTRSPRVKIDTRADSSKFS- 18262
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVI 157
+T+ D G Y A+N + A AT++VL KP V + +++
Sbjct: 18263 --LTKAKRSDGGKYVVTATN-----------TAGSFVAYATVNVLDKPGPVRNLKIV 18306
Score = 32.7 bits (73), Expect = 0.58
Identities = 45/204 (22%), Positives = 79/204 (38%), Gaps = 29/204 (14%)
Query: 39 SETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGV 98
S+T G VVG P PE +W+ V S R W + + V
Sbjct: 2086 SQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW------------YWPEDNV 2133
Query: 99 SVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVII 158
L I +T EDS + +A N + + ++A+ I+ Q+ + V ++E
Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAGET---SSHAFLLVQAKQLITFTQELQDVVAKE--- 2187
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRIN-----KPRAEDS 213
+D+ T +C +S W K+G+E+ K + + +++ D+
Sbjct: 2188 KDT---MATFEC---ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDA 2241
Query: 214 GEYHCVYHFVSAPKANATIEVKAA 237
+Y CV K A + V+ A
Sbjct: 2242 EDYSCVLVEDENVKTTAKLIVEGA 2265
Score = 32.7 bits (73), Expect = 0.58
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 19/92 (20%)
Query: 35 KSPMSETKLT------GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVT 88
K P+ + LT G+ +L C V GS IQW A S R + A
Sbjct: 8344 KPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFA------ 8397
Query: 89 VNTAYGSNGVSVLRITRLTLEDSGTYECRASN 120
+G +VL + + DSG Y C+ASN
Sbjct: 8398 -------SGTAVLELRDVAKADSGDYVCKASN 8422
Score = 32.3 bits (72), Expect = 0.76
Identities = 54/283 (19%), Positives = 104/283 (36%), Gaps = 39/283 (13%)
Query: 61 EIQWWYAEVNRAESFRQLW--DGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRA 118
E+ + E++R E+ + W DGA ++ V +L I + L+D Y C
Sbjct: 12389 EMARFECELSR-ENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC-- 12445
Query: 119 SNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHT 178
+ R ++VL++ + T I S + L C ++
Sbjct: 12446 -------------EVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAE 12492
Query: 179 LTYSYWTKNGVELSATRKNASNMEYR-----INKPRAEDSGEYHCVYHFVSAPKANATIE 233
+ W K E+ T + E R I ED+G Y+C + + + + ++
Sbjct: 12493 V---IWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC---RLPSSRTDGKVK 12546
Query: 234 V-KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFII 292
V + A + ++ EG+ A C S+ W++ + + SG + +
Sbjct: 12547 VHELAAEFISKPQNLEILEGEKAEFVC-SISKESFPVQWKRDDKTL------ESGDKYDV 12599
Query: 293 NKENYTELNIVNLQITEDPGEY--ECNATNAIGSASVVTVLRV 333
+ + +V +D G Y A A +V+ LR+
Sbjct: 12600 IADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRI 12642
Score = 31.6 bits (70), Expect = 1.3
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 235 KAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK 294
K PDI + EG+ A C+ GYP P W NG ++ S R F +
Sbjct: 1838 KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYL--NG---QLIRKSKR-FRVRY 1891
Query: 295 ENYTELNIVNLQITEDPGEYECNATNAIG 323
+ L+IV+ + + D GE + A N G
Sbjct: 1892 DGIHYLDIVDCK-SYDTGEVKVTAENPEG 1919
Score = 31.6 bits (70), Expect = 1.3
Identities = 66/346 (19%), Positives = 120/346 (34%), Gaps = 53/346 (15%)
Query: 29 QNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAE--VNRAESFRQLWDGARKRR 86
Q V P L G+ C V G P P++ W+ + +++ FR +DG
Sbjct: 1839 QKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLD 1898
Query: 87 VTVNTAYGSNGVSVL---------RITRLTLEDSGTYEC--RASNDPKRNDLRQNPSITW 135
+ +Y + V V +L ++ + R + +P+ P
Sbjct: 1899 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPG--- 1955
Query: 136 IRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKN-------- 187
+ Q + + +P T + +++ +T + + S L + +
Sbjct: 1956 -KLQFEVQKVDRPVDTTETKEVVKLKRAERITHE-KVPEESEELRSKFKRRTEEGYYEAI 2013
Query: 188 -GVELSATRKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKA---------- 236
VEL + +K+ S E + K + E H K E K
Sbjct: 2014 TAVELKSRKKDESYEEL-LRKTKDE---LLHWTKELTEEEKKALAEEGKITIPTFKPDKI 2069
Query: 237 -------APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRF 289
AP I +S+ +G DA + VG P P+ W K NG+ ++ + +
Sbjct: 2070 ELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK--NGVKIE--RSDRIY 2125
Query: 290 FIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 335
+ ++N EL ++ ED A N G S L V++
Sbjct: 2126 WYWPEDNVCEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQA 2170
Score = 31.6 bits (70), Expect = 1.3
Identities = 22/76 (28%), Positives = 31/76 (40%), Gaps = 7/76 (9%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G+ + DV G P P+I+W E + L ++T S + L I
Sbjct: 15413 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDAL-------QITKEEVSRSEAKTELSIP 15465
Query: 105 RLTLEDSGTYECRASN 120
+ ED GTY ASN
Sbjct: 15466 KAVREDKGTYTVTASN 15481
Score = 31.6 bits (70), Expect = 1.3
Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 13/76 (17%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G EL + G P P W++A ES RVTV T V+ L I
Sbjct: 29753 GRPVELVIPIAGRPPPAASWFFAGSKLRES----------ERVTVET---HTKVAKLTIR 29799
Query: 105 RLTLEDSGTYECRASN 120
T+ D+G Y N
Sbjct: 29800 ETTIRDTGEYTLELKN 29815
Score = 31.6 bits (70), Expect = 1.3
Identities = 63/300 (21%), Positives = 97/300 (32%), Gaps = 65/300 (21%)
Query: 31 AGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVN 90
A + P S T G++ CD G P P + W Q+ + + +VT
Sbjct: 32561 ARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRK--------GQVLSTSARHQVT-T 32611
Query: 91 TAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI 150
T Y S I+ + D G Y N + + ++T +A+ T + P
Sbjct: 32612 TKY----KSTFEISSVQASDEGNYSVVVENSEGKQEAEF--TLTIQKARVTEKAVTSPPR 32665
Query: 151 VTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRA 210
V S E ++ + + SH K S E KP
Sbjct: 32666 VKSPEPRVKSPEAVKSPKRVKSPEPSHP-----------------KAVSPTE---TKPTP 32705
Query: 211 EDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWI 270
+ ++ + V A P IT ++E E T +S +
Sbjct: 32706 TEKVQH---------------LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVT 32750
Query: 271 WRK-----KENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
W K KENG + G + EL I NL D GEY C + G++
Sbjct: 32751 WYKDGKKLKENGHFQFHYSADGTY---------ELKINNL-TESDQGEYVCEISGEGGTS 32800
Score = 31.2 bits (69), Expect = 1.7
Identities = 74/308 (24%), Positives = 116/308 (37%), Gaps = 60/308 (19%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFR-QLWDGARKRRVTVNTAYGSNGVSVLRI 103
G+ F L DV G P P I+W + ES R ++ + K + V A +RI
Sbjct: 23640 GETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDA--------IRI 23691
Query: 104 TRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKP---------RIVTSE 154
D G Y RASN N + VL +P VTSE
Sbjct: 23692 ------DGGQYILRASNVAGSKSFPVN-----------VKVLDRPGPPEGPVQVTGVTSE 23734
Query: 155 EVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSG 214
+ + SP LQ + SH Y + L+ T + + + + +
Sbjct: 23735 KCSLTWSP----PLQDGGSDISH---YVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGN 23787
Query: 215 EYHCVYHFVSAPKANATIEVKAAPDITGH--------KRSENKNEGQDATMYCKSVGYPH 266
EY V+ ++ K +++AP + + K E N +D+ C +
Sbjct: 23788 EY--VFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVC----WNR 23841
Query: 267 PDWIWRKKENGMPMDIVNTSG-RFFIINKENYTELNIVNLQITED-PGEYECNATNA--I 322
PD + G ++ + SG R+ NK T+L + +TED E+ +A NA +
Sbjct: 23842 PDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGV 23901
Query: 323 GSASVVTV 330
G S TV
Sbjct: 23902 GEPSPATV 23909
Score = 31.2 bits (69), Expect = 1.7
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 8/80 (10%)
Query: 252 GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-ED 310
G+D + G P P WRK E + D R+ I N ++ + L I Q+T D
Sbjct: 27286 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-----ARYSIENTDSSSLLTIP--QVTRND 27338
Query: 311 PGEYECNATNAIGSASVVTV 330
G+Y N +G TV
Sbjct: 27339 TGKYILTIENGVGEPKSSTV 27358
Score = 30.8 bits (68), Expect = 2.2
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 176 SHTLTYSYWTKNGVELSATRKNASNMEYRINK-----PRAEDSGEYHCVYHFVSAPKANA 230
SH S W KNGVE+ + K ++ ++++ EDS EY V + +A
Sbjct: 2906 SHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFV---CGNDQVSA 2962
Query: 231 TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFF 290
T+ V P + + E +D + +V Y + W K NG+ + ++ +
Sbjct: 2963 TLTV--TPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLK--NGVE---IKSTDKCQ 3015
Query: 291 IINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 332
+ K+ LNI N+ D +Y A A +A++ R
Sbjct: 3016 MRTKKLTHSLNIRNVHF-GDAADYTFVAGKATSTATLYVEAR 3056
Score = 30.8 bits (68), Expect = 2.2
Identities = 42/179 (23%), Positives = 66/179 (36%), Gaps = 38/179 (21%)
Query: 167 TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYH--------- 217
TL C +T H W + G E+ A ++YRI E G YH
Sbjct: 30946 TLVCKVTG--HPKPIVKWYRQGKEIIA-----DGLKYRIQ----EFKGGYHQLIIASVTD 30994
Query: 218 ---CVYHFVSAPKAN-----ATIEVKAAPDITGHKRSENKN-----EGQDATMYCKSVGY 264
VY + + A++EV+ I K E G+ ++ G
Sbjct: 30995 DDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGK 31054
Query: 265 PHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 323
P P W+K + D+++ +G + +I ++T L N +D G Y A N G
Sbjct: 31055 PDPVITWQKGQ-----DLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFG 31108
Score = 30.8 bits (68), Expect = 2.2
Identities = 27/110 (24%), Positives = 42/110 (38%), Gaps = 8/110 (7%)
Query: 226 PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNT 285
PKA I K P I + + A K+ G P P IW K + T
Sbjct: 32842 PKAPEPISSK--PVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAI------T 32893
Query: 286 SGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRS 335
G + ++++ ++ T D G Y C N+ GS S L +++
Sbjct: 32894 QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA 32943
Score = 30.4 bits (67), Expect = 2.9
Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 6/77 (7%)
Query: 251 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFI-INKENYTELNIVNLQITE 309
EG C+ G P P W+K +G+P+ T R+ + NK+ ++++ +
Sbjct: 1095 EGGSVVFGCQVGGNPKPHVYWKK--SGVPL---TTGYRYKVSYNKQTGECKLVISMTFAD 1149
Query: 310 DPGEYECNATNAIGSAS 326
D GEY N G S
Sbjct: 1150 DAGEYTIVVRNKHGETS 1166
Score = 30.4 bits (67), Expect = 2.9
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 263 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 322
G P P +W K+E + D R I N +EL I+ + +D G Y ATN+
Sbjct: 15130 GRPVPTKVWTKEEGELDKD------RVVIDNVGTKSEL-IIKDALRKDHGRYVITATNSC 15182
Query: 323 GS 324
GS
Sbjct: 15183 GS 15184
Score = 29.6 bits (65), Expect = 4.9
Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 236 AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKE 295
A P+ +S +G + + G P P + + +G + S F I++E
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTP--VVKFYRDGAEIQ----SSLDFQISQE 155
Query: 296 NYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
++ ED G Y NATN++G A+ L V+
Sbjct: 156 GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 29.6 bits (65), Expect = 4.9
Identities = 58/296 (19%), Positives = 101/296 (34%), Gaps = 36/296 (12%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
GD L V G+P + +W+ + R L ++K R++ N V+ L+
Sbjct: 4031 GDPATLEYTVAGTPELKPKWY-------KDGRPLV-ASKKYRISFK-----NNVAQLKFY 4077
Query: 105 RLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVL 164
L DSG Y SN+ + + T +VL + + + V+
Sbjct: 4078 SAELHDSGQYTFEISNEVGSSS-----------CETTFTVLDRDIAPFFTKPLRNVDSVV 4126
Query: 165 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKN-----ASNMEYRINKPRAEDSGEYHC- 218
T + + + W K+G E++A+ + I + D+G + C
Sbjct: 4127 NGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCR 4186
Query: 219 VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 278
+ V + ++ + V+ P S++ G + G W K +
Sbjct: 4187 ATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKEL 4246
Query: 279 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
SG I KE + L T D G Y C +N G L V+
Sbjct: 4247 ------VSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 4296
Score = 29.6 bits (65), Expect = 4.9
Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 16/90 (17%)
Query: 29 QNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFR-QLWDGARKRRV 87
+ A F K+ + D +L C+V P E+ W+ + E+ R ++ RKR +
Sbjct: 12461 EEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRIL 12519
Query: 88 TVNTAYGSNGVSVLRITRLTLEDSGTYECR 117
+ A+ LED+G Y CR
Sbjct: 12520 VIQNAH--------------LEDAGNYNCR 12535
Score = 29.3 bits (64), Expect = 6.5
Identities = 17/71 (23%), Positives = 30/71 (42%), Gaps = 6/71 (8%)
Query: 263 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 322
G P P W + + D + + +N++ + + + D GEY+ +NA
Sbjct: 17536 GVPVPTAKWTTDGSEIKTD------EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 17589
Query: 323 GSASVVTVLRV 333
GS +V L V
Sbjct: 17590 GSKTVAVHLTV 17600
Score = 29.3 bits (64), Expect = 6.5
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 13/76 (17%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G++F++ D+ G P P IQW + + + R+ + + + +SV
Sbjct: 22558 GESFKVDADIYGKPIPTIQWIKGDQELSNT----------ARLEIKSTDFATSLSVKDAV 22607
Query: 105 RLTLEDSGTYECRASN 120
R+ DSG Y +A N
Sbjct: 22608 RV---DSGNYILKAKN 22620
Score = 28.9 bits (63), Expect = 8.4
Identities = 30/124 (24%), Positives = 45/124 (36%), Gaps = 14/124 (11%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGAR-KRRVTVNT 91
FV P+S L G VVG P PE W++ DG + T
Sbjct: 1459 FVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFH-------------DGQQIVNDYTHKV 1505
Query: 92 AYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV 151
+G L I T DSG + A N R+ + ++ + Q ++K + V
Sbjct: 1506 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNV 1565
Query: 152 TSEE 155
+E
Sbjct: 1566 NIKE 1569
Score = 28.9 bits (63), Expect = 8.4
Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 263 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 322
G PHP W+K E+ ++V +S ++K + + + I+ +D G Y A N+
Sbjct: 18924 GKPHPTCKWKKGED----EVVTSS--HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSS 18977
Query: 323 GS 324
G+
Sbjct: 18978 GT 18979
Score = 28.9 bits (63), Expect = 8.4
Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 10/97 (10%)
Query: 238 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 297
PD+ S + GQD + G P P W K +G+P+ + R + + +
Sbjct: 23230 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK--DGLPL---KQTTRINVTDSLDL 23284
Query: 298 TELNIVNLQITEDPGEYECNATNAIG----SASVVTV 330
T L+I +D G+Y N +G S +VT+
Sbjct: 23285 TTLSIKETH-KDDGGQYGITVANVVGQKTASIEIVTL 23320
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 87.4 bits (215), Expect = 2e-17
Identities = 89/314 (28%), Positives = 129/314 (41%), Gaps = 45/314 (14%)
Query: 26 GAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKR 85
G+ FV P + L G++ L C G P P I W R + D
Sbjct: 337 GSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISW-----TRGDRTPLPVDP---- 387
Query: 86 RVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVL 145
RV + + G L I + DSG Y C A+N+ I + A A I V
Sbjct: 388 RVNITPSGG------LYIQNVVQGDSGEYACSATNN-----------IDSVHATAFIIVQ 430
Query: 146 QKPRI-VTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA--SNME 202
P+ VT ++ ++ + V QC + + WTK G +LS R++ S+
Sbjct: 431 ALPQFTVTPQDRVVIEGQT--VDFQCEAKGNPPPVIA--WTKGGSQLSVDRRHLVLSSGT 486
Query: 203 YRINKPRAEDSGEYHC-VYHFVSAPK--ANATIEVKAAPDITGHKRSENKNEGQDATMYC 259
RI+ D G+Y C + + + K A+ T++ + P G + + C
Sbjct: 487 LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPC 546
Query: 260 KSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 319
S G P P W K +G+ V SG+F I + E + +N V D G YEC A
Sbjct: 547 SSQGEPEPAITWNK--DGVQ---VTESGKFHI-SPEGFLTINDVG---PADAGRYECVAR 597
Query: 320 NAIGSASVVTVLRV 333
N IGSASV VL V
Sbjct: 598 NTIGSASVSMVLSV 611
Score = 67.0 bits (162), Expect = 3e-11
Identities = 77/309 (24%), Positives = 126/309 (40%), Gaps = 37/309 (11%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
P +G+ C G+P PEI W R + + K +N +
Sbjct: 252 PQDADVTSGNTVYFTCRAEGNPKPEIIW----------LRNNNELSMKTDSRLNLL--DD 299
Query: 97 GVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEV 156
G +++ T+ T D G Y+C A N Q ++ + + A + + +P+ + EV
Sbjct: 300 GTLMIQNTQET--DQGIYQCMAKNVAGEVKT-QEVTLRYFGSPARPTFVIQPQ---NTEV 353
Query: 157 IIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNG---VELSATRKNASNMEYRINKPRAEDS 213
++ +S VTL+C+ T H WT+ + + + I DS
Sbjct: 354 LVGES----VTLECSATG--HPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDS 407
Query: 214 GEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 272
GEY C + + + A A I V+A P T + EGQ C++ G P P W
Sbjct: 408 GEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWT 467
Query: 273 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 332
K + + +D R ++ ++ V L D G+YEC A N IGS VV L
Sbjct: 468 KGGSQLSVD------RRHLVLSSGTLRISGVALH---DQGQYECQAVNIIGSQKVVAHLT 518
Query: 333 VRSHLAPLW 341
V+ + P++
Sbjct: 519 VQPRVTPVF 527
Score = 38.5 bits (88), Expect = 0.011
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 7/93 (7%)
Query: 238 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 297
P IT + + G C++ G P P+ IW + N + M T R +++
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSM---KTDSRLNLLDDGT- 301
Query: 298 TELNIVNLQITEDPGEYECNATNAIGSASVVTV 330
L I N Q T D G Y+C A N G V
Sbjct: 302 --LMIQNTQET-DQGIYQCMAKNVAGEVKTQEV 331
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 75.9 bits (185), Expect = 6e-14
Identities = 82/306 (26%), Positives = 124/306 (40%), Gaps = 45/306 (14%)
Query: 34 VKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAY 93
V P + T G ++ C +G+P P I W +VN + AR R+
Sbjct: 304 VHFPFTVTAAKGTTVKMECFALGNPVPTITWM--KVNG-----YIPSKARLRK------- 349
Query: 94 GSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS 153
+VL I + L+D+G YECRA N +N R + V P V
Sbjct: 350 ---SQAVLEIPNVQLDDAGIYECRAENSRGKNSFR-----------GQLQVYTYPHWVEK 395
Query: 154 EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELS-ATRKNASNMEYRINKPRAED 212
DS P+ +C T TY W KNGV LS +R N I+ D
Sbjct: 396 LNDTQLDSG-SPLRWECKATGKPRP-TYR-WLKNGVPLSPQSRVEMVNGVLMIHNVNQSD 452
Query: 213 SGEYHCV-YHFVSAPKANATIEVKAAPD---ITGHKRSENKNEGQDATMYCKSVGYPHPD 268
+G Y C+ + A A+A +++ A+ + K++ + Q+ + CK G P P
Sbjct: 453 AGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPT 512
Query: 269 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 328
W+K + V + R I+ + L I+N D G+Y C N GSA ++
Sbjct: 513 ISWKKGDRA-----VRENKRIAILPDGS---LRILNAS-KSDEGKYVCRGENVFGSAEII 563
Query: 329 TVLRVR 334
L V+
Sbjct: 564 ASLSVK 569
Score = 40.8 bits (94), Expect = 0.002
Identities = 78/312 (25%), Positives = 115/312 (36%), Gaps = 60/312 (19%)
Query: 50 LYCDVVGSPTPEIQWWY--AEVNRAESFR-QLWDGARKRRVTVNTAYGSNGVSVLRITRL 106
L C+V G+P P +W E++ +R L DG T SN
Sbjct: 121 LNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDG---------TFIISNPSEA------ 165
Query: 107 TLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPV 166
+DSG Y+C A+N SI A + L T V +R+ V
Sbjct: 166 --KDSGHYQCLATNTVG--------SILSREATLQFAYLGNFSGRTRSAVSVREGQ--GV 213
Query: 167 TLQCNLTSSSHTLTYSYWTKNG-----VELSATRKNASNMEYRINKPRAEDSGEYHCVY- 220
L C+ S + YS W N E S + I+K + D G Y C+
Sbjct: 214 VLMCSPPPHSPEIIYS-WVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVK 272
Query: 221 ------HFVSAPKA----NATIEVKAAPDITGH-KRSENKNEGQDATMYCKSVGYPHPDW 269
+S P N + + P I H + +G M C ++G P P
Sbjct: 273 NTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTI 332
Query: 270 IWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 329
W K +P + R +++ L I N+Q+ +D G YEC A N+ G S
Sbjct: 333 TWMKVNGYIP-----SKARL----RKSQAVLEIPNVQL-DDAGIYECRAENSRGKNSFRG 382
Query: 330 VLRVRSHLAPLW 341
L+V ++ P W
Sbjct: 383 QLQVYTY--PHW 392
Score = 33.9 bits (76), Expect = 0.26
Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 16/111 (14%)
Query: 219 VYHFVSAPKANATIE-----VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRK 273
+YH A K + +++ V+ DI S+ K + C+ G P P + W +
Sbjct: 82 LYHSSDAFKQDESVDYGPVFVQEPDDIIFPTDSDEKK----VALNCEVRGNPVPSYRWLR 137
Query: 274 KENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 324
NG +D+ + R+ +I+ I N +D G Y+C ATN +GS
Sbjct: 138 --NGTEIDL-ESDYRYSLIDGT----FIISNPSEAKDSGHYQCLATNTVGS 181
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 75.9 bits (185), Expect = 6e-14
Identities = 82/306 (26%), Positives = 124/306 (40%), Gaps = 45/306 (14%)
Query: 34 VKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAY 93
V P + T G ++ C +G+P P I W +VN + AR R+
Sbjct: 230 VHFPFTVTAAKGTTVKMECFALGNPVPTITWM--KVNG-----YIPSKARLRK------- 275
Query: 94 GSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS 153
+VL I + L+D+G YECRA N +N R + V P V
Sbjct: 276 ---SQAVLEIPNVQLDDAGIYECRAENSRGKNSFR-----------GQLQVYTYPHWVEK 321
Query: 154 EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELS-ATRKNASNMEYRINKPRAED 212
DS P+ +C T TY W KNGV LS +R N I+ D
Sbjct: 322 LNDTQLDSG-SPLRWECKATGKPRP-TYR-WLKNGVPLSPQSRVEMVNGVLMIHNVNQSD 378
Query: 213 SGEYHCV-YHFVSAPKANATIEVKAAPD---ITGHKRSENKNEGQDATMYCKSVGYPHPD 268
+G Y C+ + A A+A +++ A+ + K++ + Q+ + CK G P P
Sbjct: 379 AGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPT 438
Query: 269 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 328
W+K + V + R I+ + L I+N D G+Y C N GSA ++
Sbjct: 439 ISWKKGDRA-----VRENKRIAILPDGS---LRILNAS-KSDEGKYVCRGENVFGSAEII 489
Query: 329 TVLRVR 334
L V+
Sbjct: 490 ASLSVK 495
Score = 40.8 bits (94), Expect = 0.002
Identities = 78/312 (25%), Positives = 115/312 (36%), Gaps = 60/312 (19%)
Query: 50 LYCDVVGSPTPEIQWWY--AEVNRAESFR-QLWDGARKRRVTVNTAYGSNGVSVLRITRL 106
L C+V G+P P +W E++ +R L DG T SN
Sbjct: 47 LNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDG---------TFIISNPSEA------ 91
Query: 107 TLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPV 166
+DSG Y+C A+N SI A + L T V +R+ V
Sbjct: 92 --KDSGHYQCLATNTVG--------SILSREATLQFAYLGNFSGRTRSAVSVREGQ--GV 139
Query: 167 TLQCNLTSSSHTLTYSYWTKNG-----VELSATRKNASNMEYRINKPRAEDSGEYHCVY- 220
L C+ S + YS W N E S + I+K + D G Y C+
Sbjct: 140 VLMCSPPPHSPEIIYS-WVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVK 198
Query: 221 ------HFVSAPKA----NATIEVKAAPDITGH-KRSENKNEGQDATMYCKSVGYPHPDW 269
+S P N + + P I H + +G M C ++G P P
Sbjct: 199 NTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTI 258
Query: 270 IWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 329
W K +P + R +++ L I N+Q+ +D G YEC A N+ G S
Sbjct: 259 TWMKVNGYIP-----SKARL----RKSQAVLEIPNVQL-DDAGIYECRAENSRGKNSFRG 308
Query: 330 VLRVRSHLAPLW 341
L+V ++ P W
Sbjct: 309 QLQVYTY--PHW 318
Score = 32.3 bits (72), Expect = 0.76
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
Query: 250 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 309
++ + + C+ G P P + W + NG +D+ + R+ +I+ I N +
Sbjct: 40 SDEKKVALNCEVRGNPVPSYRWLR--NGTEIDL-ESDYRYSLIDGT----FIISNPSEAK 92
Query: 310 DPGEYECNATNAIGS 324
D G Y+C ATN +GS
Sbjct: 93 DSGHYQCLATNTVGS 107
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 70.5 bits (171), Expect = 3e-12
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 42/312 (13%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F P + GD L C GSPTP I W + R + +G ++
Sbjct: 2940 FTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVND-------RPVTEGVSEQ------- 2985
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
+G S L+ ++ EDSGTY C A N R +A + + V + P ++
Sbjct: 2986 ---DGGSTLQRAAVSREDSGTYVCWAENRVGRT-----------QAVSFVHVKEAP-VLQ 3030
Query: 153 SEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVEL--SATRKNASNMEYRINKPRA 210
E PV ++Q + + +W K+G+ L S R N I++
Sbjct: 3031 GEAFSYLVEPV-GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTER 3089
Query: 211 EDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 269
+D+G Y C+ + + K + +++AP + G D + C++ G P P
Sbjct: 3090 DDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTI 3149
Query: 270 IWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 329
W + G P+ S R + + N+ T D G Y+C A N +GSA+
Sbjct: 3150 EW--LQAGQPL---RASRRLRTLPDGSLWLENVE----TGDAGTYDCVAHNLLGSATARA 3200
Query: 330 VLRVRSHLAPLW 341
L VR W
Sbjct: 3201 FLVVRGEPQGSW 3212
Score = 64.7 bits (156), Expect = 1e-10
Identities = 84/316 (26%), Positives = 123/316 (38%), Gaps = 52/316 (16%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
P+++ L + L C G P P++ W+ + W G VTV+
Sbjct: 701 PVNKAVLENASVTLECLASGVPPPDVSWF-----KGHQPVSSWMG-----VTVSV----- 745
Query: 97 GVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEV 156
VLRI + L D+G+Y C ASN +LR + V PRI +
Sbjct: 746 DGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYG-----------LRVNVPPRITLPPSL 794
Query: 157 IIRDSPVL---PVTLQCNLTSS-SHTLTYSYWTKNGVELS-----ATRKNASNMEYRINK 207
PVL PV L CN T + S TL W K+G +S + +
Sbjct: 795 ---PGPVLVNTPVRLTCNATGAPSPTL---MWLKDGNPVSPAGTPGLQVFPGGRVLTLAS 848
Query: 208 PRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
RA DSG Y CV V + + ++V P I G + + + + + C+S P
Sbjct: 849 ARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPP 908
Query: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
P W K +G P++ G +K L V+ D G Y C A N G +
Sbjct: 909 PVLSWWK--DGRPLE--PRPGVHLSADK----ALLQVDRADVWDAGHYTCEALNQAGRSE 960
Query: 327 VVTVLRVRSHLAPLWP 342
L V +AP++P
Sbjct: 961 KHYNLNV--WVAPVFP 974
Score = 63.5 bits (153), Expect = 3e-10
Identities = 72/288 (25%), Positives = 114/288 (39%), Gaps = 50/288 (17%)
Query: 50 LYCDVVGSPTPEIQWWYAE--VNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLT 107
L C+ +G P P I+W+ E V+ E Y G +L++T+
Sbjct: 1181 LLCEAMGIPPPAIRWFRGEEPVSPGED-----------------TYLLAGGWMLKMTQTQ 1223
Query: 108 LEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSE-EVIIRDSPVLPV 166
+DSG Y C ASN+ + R+N S + VL P I + E +I+
Sbjct: 1224 EQDSGLYSCLASNE--AGEARRNFS---------VEVLVPPSIENEDLEEVIKVLDGQTA 1272
Query: 167 TLQCNLTSSSHTLTYSYWTKNGVELS---ATRKNASNMEYRINKPRAEDSGEYHCV-YHF 222
L CN+T H W K+G L+ A + + ++ + +G Y C+ +
Sbjct: 1273 HLMCNVT--GHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANA 1330
Query: 223 VSAPKANATIEVKAAPDITGHKRSENKNE-----GQDATMYCKSVGYPHPDWIWRKKENG 277
V + + V AP I G E ++ C+++ +P P+ W K +G
Sbjct: 1331 VGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK--DG 1388
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
P + I L I+N Q ED G+Y C TN +G A
Sbjct: 1389 APFEASRN-----IQLLPGTHGLQILNAQ-KEDAGQYTCVVTNELGEA 1430
Score = 58.9 bits (141), Expect = 8e-09
Identities = 79/298 (26%), Positives = 117/298 (39%), Gaps = 54/298 (18%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE 109
L C G P P + W +++ QL GAR + Y + L I +
Sbjct: 2685 LTCHSTGIPAPTVSW-------SKAGAQL--GAR------GSGYRVSPSGALEIGQALPI 2729
Query: 110 DSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKP---RIVTSEEVIIRDSPVLPV 166
+G Y C A RN ++ QA+ V P R V EEV+
Sbjct: 2730 HAGRYTCSA-----RNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVL--------- 2775
Query: 167 TLQCNLTSSSH-TLTYSYWTKNGVELSA--TRKNASNMEYRINKPRAEDSGEYHCVY-HF 222
L C + T+T W K G+ ++ + + + RI ED+G Y C+ +
Sbjct: 2776 -LPCEASGIPRPTIT---WQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS 2831
Query: 223 VSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDI 282
+ + V+ P I + EG A + CK+ G P P+ W K +G P +
Sbjct: 2832 AGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDK--DGQP--V 2887
Query: 283 VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPL 340
G+F I + EL + NL+ +D G Y C A NA+G A R R HL L
Sbjct: 2888 SGAEGKFTI---QPSGELLVKNLE-GQDAGTYTCTAENAVGRA------RRRVHLTIL 2935
Score = 55.8 bits (133), Expect = 6e-08
Identities = 72/302 (23%), Positives = 114/302 (37%), Gaps = 50/302 (16%)
Query: 49 ELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTL 108
+L C+ G PTP I W+ DGA T Y + G L++ R
Sbjct: 330 QLLCEARGVPTPNITWFK-------------DGALLPTST-KVVY-TRGGRQLQLGRAQS 374
Query: 109 EDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI--VTSEEVIIRDSPVLPV 166
D+G Y C+ASN ++ + V P I +++ PV
Sbjct: 375 SDAGVYTCKASN-----------AVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPV 423
Query: 167 TLQCNLTSSSHTLTYSYWTKNGV---ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFV 223
L+C + H W G+ E + +R R+ P SG Y CV
Sbjct: 424 ALEC--VARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV---A 478
Query: 224 SAPKANA----TIEVKAAPDITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKENG 277
S+P A ++EV+ P + + GQ + C++ G P P W +NG
Sbjct: 479 SSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL--QNG 536
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHL 337
P + +G + T L+I ++++ + G + C ATN G+A + V
Sbjct: 537 RPAE--ELAG---VQVASQGTTLHIDHVEL-DHSGLFACQATNEAGTAGAEVEVSVHGEW 590
Query: 338 AP 339
AP
Sbjct: 591 AP 592
Score = 55.8 bits (133), Expect = 6e-08
Identities = 75/302 (24%), Positives = 116/302 (38%), Gaps = 51/302 (16%)
Query: 39 SETKLT-GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNG 97
+E LT G EL CD G+P P I W DG R+ N S
Sbjct: 2312 TELSLTPGAPMELLCDAQGTPQPNITWHK-------------DGQALTRLENN----SRA 2354
Query: 98 VSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVL--QKPRIVTSEE 155
VLR+ D+G Y C A + + +R QA +++ + PR V
Sbjct: 2355 TRVLRV-----RDAGLYTCLAESPAGAIEKSFR-----VRVQAPPNIVGPRGPRFVVG-- 2402
Query: 156 VIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRA---ED 212
+ P L + + W ++G+ L R + +A D
Sbjct: 2403 -------LAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTAD 2455
Query: 213 SGEYHCVYHFVSAPKANA-TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIW 271
SG+Y C + + A +E+ P I + N + Q A + C++ G P P W
Sbjct: 2456 SGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW 2515
Query: 272 RKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 331
RK + +P+D S RF I+ + + + + +D G Y C A+N+ GS L
Sbjct: 2516 RK--DRVPLD--PRSPRFEILPEGSLR----IQPVLAQDAGHYLCLASNSAGSDRQGRDL 2567
Query: 332 RV 333
RV
Sbjct: 2568 RV 2569
Score = 53.9 bits (128), Expect = 2e-07
Identities = 78/302 (25%), Positives = 119/302 (39%), Gaps = 63/302 (20%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
L G L C+V G P P++ W+ DG R + +GV +L+
Sbjct: 1267 LDGQTAHLMCNVTGHPQPKLTWFK-------------DGRPLARGDAH-HISPDGV-LLQ 1311
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV------TSEEV 156
+ + L +G Y C A+N ++ +SVL P I+ EEV
Sbjct: 1312 VLQANLSSAGHYSCIAAN-----------AVGEKTKHFQLSVLLAPTILGGAEDSADEEV 1360
Query: 157 IIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRK---NASNMEYRINKPRAED 212
+ + P++L C L S +T W K+G A+R +I + ED
Sbjct: 1361 TVTVNN--PISLICEALAFPSPNIT---WMKDGAPFEASRNIQLLPGTHGLQILNAQKED 1415
Query: 213 SGEYHCVY-HFVSAPKANATIEVKAAPDIT--------GHKRSENKNEGQDATMYCKSVG 263
+G+Y CV + + N +EV P I+ G K + K T+ C+S
Sbjct: 1416 AGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTK-VNSTLTLECESWA 1474
Query: 264 YPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE--DPGEYECNATNA 321
P P W K +G P V S R ++ E ++ +Q T+ D G Y C ATN
Sbjct: 1475 VPPPTIRWYK--DGQP---VTPSSRLQVLG-----EGRLLQIQPTQVSDSGRYLCVATNV 1524
Query: 322 IG 323
G
Sbjct: 1525 AG 1526
Score = 52.4 bits (124), Expect = 7e-07
Identities = 63/292 (21%), Positives = 113/292 (38%), Gaps = 44/292 (15%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE 109
LYCD P P++ W +R+ + V+V G VL+I + E
Sbjct: 1579 LYCDTNAIPPPDLTW----------YREDQPLSAGDEVSV-----LQGGRVLQIPLVRAE 1623
Query: 110 DSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPV---LPV 166
++G Y C+ASN+ + W+ + + VL P I+ E ++ + V V
Sbjct: 1624 NAGRYSCKASNEVGED---------WLHYE--LLVLTPPVILGDTEELVEEVTVNASSTV 1672
Query: 167 TLQCNLTSSSHTLTYSYWTKNGVELSATRK---NASNMEYRINKPRAEDSGEYHCV-YHF 222
+LQC + + + W +NG+ S + + +++ D+ Y CV +
Sbjct: 1673 SLQC--PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQ 1730
Query: 223 VSAPKANATIEVKAAPDITGHKRSE-NKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMD 281
+ + T+ V+ P I G + ++ C +P+P+ W K + +
Sbjct: 1731 AGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSL- 1789
Query: 282 IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
F++ + +L L D G Y C A NA G + L V
Sbjct: 1790 ----GEEVFLLPGTHTLQLGRARL---SDSGMYTCEALNAAGRDQKLVQLSV 1834
Score = 50.1 bits (118), Expect = 4e-06
Identities = 74/320 (23%), Positives = 120/320 (37%), Gaps = 58/320 (18%)
Query: 15 LLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAES 74
+LV + P Q+A V+ GD L C+ P P + W+
Sbjct: 1834 VLVPPAFRQAPRGPQDAVLVR--------VGDKAVLSCETDALPEPTVTWYK-------- 1877
Query: 75 FRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSIT 134
DG + V G L I + D G Y C+ SN
Sbjct: 1878 -----DG--QPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSN-------------- 1916
Query: 135 WIRAQA----TISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNG- 188
+ +A T++V P + + P+ L C+++ + T+T W K+
Sbjct: 1917 -VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVT---WLKDRM 1972
Query: 189 -VELSATRKNASNM-EYRINKPRAEDSGEYHCVYHFVSAP-KANATIEVKAAPDI--TGH 243
VE SA S ++++ + +G Y CV A + + + V AP I +G
Sbjct: 1973 PVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGV 2032
Query: 244 KRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIV 303
R + EGQ+ + C++ G P PD W K + + D + RF++ + L +
Sbjct: 2033 AREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQD-MGPHLRFYL----DGGSLVLK 2087
Query: 304 NLQITEDPGEYECNATNAIG 323
L+ D G Y C A N G
Sbjct: 2088 GLR-ASDAGAYTCVAHNPAG 2106
Score = 50.1 bits (118), Expect = 4e-06
Identities = 71/302 (23%), Positives = 114/302 (37%), Gaps = 56/302 (18%)
Query: 45 GDAFELYCDVVGSPTPEIQWWY-AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRI 103
G EL C+ G P P + W E ++S Q G S L++
Sbjct: 2230 GSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQ-------------------GPS-LQL 2269
Query: 104 TRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS-EEVIIRDSP 162
+ DSGTY C A ++ R ++V++ P I S + + +P
Sbjct: 2270 EAVGAGDSGTYSCVAVSEAGE-----------ARRHFQLTVMEPPHIEDSGQPTELSLTP 2318
Query: 163 VLPVTLQCNLTSSSH-TLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYH 221
P+ L C+ + +T W K+G L+ N+ R D+G Y C+
Sbjct: 2319 GAPMELLCDAQGTPQPNIT---WHKDGQALTRLENNSRATRVL----RVRDAGLYTCLAE 2371
Query: 222 F-VSAPKANATIEVKAAPDITGHKRSE---NKNEGQDATMYCKSVGYPHPDWIWRKKENG 277
A + + + V+A P+I G + GQ + C P P W + +G
Sbjct: 2372 SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQ-LVLECSVEAEPAPKITWHR--DG 2428
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHL 337
+ ++ + + +L ++ T D G+Y C A NA GS SV RV H
Sbjct: 2429 I---VLQEDAHTQFPERGRFLQLQALS---TADSGDYSCTARNAAGSTSV--AFRVEIHT 2480
Query: 338 AP 339
P
Sbjct: 2481 VP 2482
Score = 47.4 bits (111), Expect = 2e-05
Identities = 69/312 (22%), Positives = 113/312 (36%), Gaps = 58/312 (18%)
Query: 36 SPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGS 95
SP + T L C+ GSP P + WW DG + AY
Sbjct: 2578 SPSNLTLTAHTPALLPCEASGSPKPLVVWWK-------------DGQKLDFRLQQGAYRL 2624
Query: 96 NGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEE 155
+ L +T +DS +EC SN+ Q T+ V P + ++
Sbjct: 2625 LPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLY---------QVTVHV---PPTIADDQ 2672
Query: 156 VIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAED-- 212
+ + PV L C+ T + T++ W+K G +L A YR++ A +
Sbjct: 2673 TDFTVTMMAPVVLTCHSTGIPAPTVS---WSKAGAQLGARGSG-----YRVSPSGALEIG 2724
Query: 213 ------SGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 265
+G Y C + + + V+A+P + ++ + C++ G P
Sbjct: 2725 QALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIP 2784
Query: 266 HPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 322
P W+K+ + + V G+ I + ED G Y C A N+
Sbjct: 2785 RPTITWQKEGLNVATGVSTQVLPGGQLRIAHAS------------PEDAGNYLCIAKNSA 2832
Query: 323 GSASVVTVLRVR 334
GSA T L V+
Sbjct: 2833 GSAMGKTRLVVQ 2844
Score = 46.2 bits (108), Expect = 5e-05
Identities = 74/307 (24%), Positives = 114/307 (37%), Gaps = 46/307 (14%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
T + + L CDV P PE+ W+ + ++A S + + G
Sbjct: 1757 TAILNSSVSLPCDVHAHPNPEVTWY--KDSQALSLGE-------------EVFLLPGTHT 1801
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRD 160
L++ R L DSG Y C A N R+ + + + Q PR + V++R
Sbjct: 1802 LQLGRARLSDSGMYTCEALNAAGRDQ-----KLVQLSVLVPPAFRQAPR-GPQDAVLVRV 1855
Query: 161 SPVLPVTLQCNLTS-SSHTLTYSYWTKNGVEL---SATRKNASNMEYRINKPRAEDSGEY 216
L C + T+T W K+G L T+ I + + D G Y
Sbjct: 1856 GD--KAVLSCETDALPEPTVT---WYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLY 1910
Query: 217 HCVYHFVSAPKANA-TIEVKAAPDITGHK-RSENKNEGQDATMYCKSVGYPHPDWIWRKK 274
C V+ T+ V+ P K + ++ G + C G P P W K
Sbjct: 1911 SCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLK- 1969
Query: 275 ENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS---VVTVL 331
+ MP V +S ++++ L + LQ + G Y C A N A VV VL
Sbjct: 1970 -DRMP---VESSAVHGVVSRGG--RLQLSRLQPAQ-AGTYTCVAENTQAEARKDFVVAVL 2022
Query: 332 ---RVRS 335
R+RS
Sbjct: 2023 VAPRIRS 2029
Score = 45.8 bits (107), Expect = 7e-05
Identities = 71/315 (22%), Positives = 118/315 (37%), Gaps = 54/315 (17%)
Query: 23 PGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGA 82
P P + AG + + L G EL C G PTP+++W + + + G
Sbjct: 213 PAPPSVLGAGAAQEVLG---LAGADVELQCWTSGVPTPQVEW-------TKDRQPVLPGG 262
Query: 83 RKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATI 142
+V VLRIT + D G Y+C A + P R +R A
Sbjct: 263 PHLQV-------QEDGQVLRITGSHVGDEGRYQCVAFS-PAGQQARD----FQLRVHAPP 310
Query: 143 SVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRK---NAS 199
++ T E ++ D V + + + + T W K+G L + K
Sbjct: 311 TIWGSNE--TGEVAVMEDHLVQLLCEARGVPTPNIT-----WFKDGALLPTSTKVVYTRG 363
Query: 200 NMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDIT---GHKRSENKNEGQDA 255
+ ++ + ++ D+G Y C + V A + ++V P I G G+
Sbjct: 364 GRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPV 423
Query: 256 TMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE-- 313
+ C + G+P P W G+P+ N S T+ +++ L E PGE
Sbjct: 424 ALECVARGHPSPTLSWH--HEGLPVAESNES--------RLETDGSVLRL---ESPGEAS 470
Query: 314 ---YECNATNAIGSA 325
Y C A++ G A
Sbjct: 471 SGLYSCVASSPAGEA 485
Score = 45.8 bits (107), Expect = 7e-05
Identities = 65/312 (20%), Positives = 107/312 (34%), Gaps = 60/312 (19%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
L L C+ G+P+P + W L DG G VL
Sbjct: 799 LVNTPVRLTCNATGAPSPTLMW-------------LKDGNPVSPAGTPGLQVFPGGRVLT 845
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSE---EVIIR 159
+ DSG Y C A + ++ R + V P I+ E V+
Sbjct: 846 LASARASDSGRYSCVAVS-----------AVGEDRQDVVLQVHMPPSILGEELNVSVVAN 894
Query: 160 DSPVLPVTLQCNLTSSSHTLTYSY--WTKNGVELS---ATRKNASNMEYRINKPRAEDSG 214
+S V L+C SH + W K+G L +A ++++ D+G
Sbjct: 895 ES----VALECQ----SHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAG 946
Query: 215 EYHC-VYHFVSAPKANATIEVKAAPDIT-GHKRSENKNEGQDATMYCKSVGYPHPDWIWR 272
Y C + + + + V AP + EG ++ C+ G P P WR
Sbjct: 947 HYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWR 1006
Query: 273 KKENGMP-----MDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASV 327
K +P + V+ GR + + + G Y C +N +G++S
Sbjct: 1007 KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQ-----------EGTYTCECSNVVGNSS- 1054
Query: 328 VTVLRVRSHLAP 339
L++ H+ P
Sbjct: 1055 -QDLQLEVHVPP 1065
Score = 42.0 bits (97), Expect = 0.001
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 11/133 (8%)
Query: 204 RINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAAPDITGHKRSENKNEGQD--ATMYCK 260
RI D G Y CV + +A + + V A P I G + +D + C+
Sbjct: 275 RITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCE 334
Query: 261 SVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATN 320
+ G P P+ W K +P TS + ++ +L + Q + D G Y C A+N
Sbjct: 335 ARGVPTPNITWFKDGALLP-----TSTK--VVYTRGGRQLQLGRAQ-SSDAGVYTCKASN 386
Query: 321 AIGSASVVTVLRV 333
A+G+A T L V
Sbjct: 387 AVGAAEKATRLDV 399
Score = 42.0 bits (97), Expect = 0.001
Identities = 63/292 (21%), Positives = 106/292 (36%), Gaps = 45/292 (15%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
+ ++ L C P P + WW + R L + R V+ S ++L+
Sbjct: 892 VANESVALECQSHAMPPPVLSWW-------KDGRPL-----EPRPGVHL---SADKALLQ 936
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
+ R + D+G Y C A N R++ N ++ W+ A + L++ +T E
Sbjct: 937 VDRADVWDAGHYTCEALNQAGRSEKHYNLNV-WV---APVFPLRESHTLTVREGH----- 987
Query: 163 VLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME-----YRINKPRAEDSGEYH 217
P +L C W K+G L ++ + + + G Y
Sbjct: 988 --PTSLSCECRGVPFPKIS--WRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYT 1043
Query: 218 C-VYHFVSAPKANATIEVKAAPDITGHKRSENK-NEGQD--ATMYCKSVGYPHPDWIWRK 273
C + V + +EV P I G + + + QD AT+ C + G P P W +
Sbjct: 1044 CECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWER 1103
Query: 274 KENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
+G P+ G + +N + V G Y C A N G A
Sbjct: 1104 --DGQPV------GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRA 1147
Score = 41.2 bits (95), Expect = 0.002
Identities = 57/251 (22%), Positives = 91/251 (36%), Gaps = 41/251 (16%)
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS--EEVII 158
L+I ++ L D G Y C A+N + + + + VL P I + ++
Sbjct: 659 LQIEKVDLRDEGIYTCAATNLAGES-----------KREVALKVLVPPNIEPGPVNKAVL 707
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSA---TRKNASNMEYRINKPRAEDSGE 215
++ VTL+C L S S W K +S+ + RI + + D+G
Sbjct: 708 ENA---SVTLEC-LASGVPPPDVS-WFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGS 762
Query: 216 YHCVYHFVSAP-------KANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPD 268
Y CV V+ + N + P + G + C + G P P
Sbjct: 763 YRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNT-----PVRLTCNATGAPSPT 817
Query: 269 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 328
+W K +G P+ T G T + D G Y C A +A+G
Sbjct: 818 LMWLK--DGNPVSPAGTPGLQVFPGGRVLT----LASARASDSGRYSCVAVSAVGEDRQD 871
Query: 329 TVLRVRSHLAP 339
VL+V H+ P
Sbjct: 872 VVLQV--HMPP 880
Score = 40.0 bits (92), Expect = 0.004
Identities = 52/232 (22%), Positives = 84/232 (36%), Gaps = 31/232 (13%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G+ + C V GSP + W L DG +GS LRI+
Sbjct: 2137 GELVTMVCPVRGSPPIHVSW-------------LKDGLPLPLSQRTLLHGSG--HTLRIS 2181
Query: 105 RLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVL 164
++ L D+G + C A++ D Q + + +P ++ V++R S
Sbjct: 2182 KVQLADAGIFTCVAASPAGVADRN-------FTLQVQVPPVLEPVEFQNDVVVVRGS--- 2231
Query: 165 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCV-YHFV 223
V L C + L W K+G L ++ ++ A DSG Y CV
Sbjct: 2232 LVELPCE--ARGVPLPLVSWMKDGEPL-LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEA 2288
Query: 224 SAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRK 273
+ + + V P I +G + G + C + G P P+ W K
Sbjct: 2289 GEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHK 2340
Score = 39.7 bits (91), Expect = 0.005
Identities = 65/319 (20%), Positives = 112/319 (35%), Gaps = 78/319 (24%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGAR-KRRVTVNTAYGSNGVS 99
T + L C+ + P+P I W + DGA + + G++G+
Sbjct: 1361 TVTVNNPISLICEALAFPSPNITW-------------MKDGAPFEASRNIQLLPGTHGLQ 1407
Query: 100 VLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIR 159
+L + ED+G Y C +N+ + + VL P I +
Sbjct: 1408 ILNAQK---EDAGQYTCVVTNELGEAVKNYH-----------VEVLIPPSIS-------K 1446
Query: 160 DSPVLPVTLQCNLTSSSHTLTYSY-----------WTKNGVELSATRKNASNMEYR---I 205
D P+ V ++ T + TLT W K+G ++ + + E R I
Sbjct: 1447 DDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQI 1506
Query: 206 NKPRAEDSGEYHCVYHFVSAPKA---NATIEV----------KAAPDITGHKRSENKN-- 250
+ DSG Y CV V+ N I+V AA +I +
Sbjct: 1507 QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVT 1566
Query: 251 ------EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVN 304
E A +YC + P PD W +++ + + ++ ++ +V
Sbjct: 1567 EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPL-----SAGDEVSVLQGGRVLQIPLVR 1621
Query: 305 LQITEDPGEYECNATNAIG 323
E+ G Y C A+N +G
Sbjct: 1622 ---AENAGRYSCKASNEVG 1637
Score = 37.4 bits (85), Expect = 0.024
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 212 DSGEYHC-VYHFVSAPKANATIEVKAAPDIT--GHKRSENKNEGQDATMYCKSVGYPHPD 268
DSG+Y C + V + A + V P I G K + + GQ T+ C + G+P P+
Sbjct: 68 DSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPE 127
Query: 269 WIWRKKEN--GMPM 280
+W K G+P+
Sbjct: 128 IVWLKDAQLVGVPL 141
Score = 37.0 bits (84), Expect = 0.031
Identities = 71/307 (23%), Positives = 113/307 (36%), Gaps = 53/307 (17%)
Query: 50 LYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLT 107
L C+ P P I+W+ V + + L +G +L+I
Sbjct: 1468 LECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGR-----------------LLQIQPTQ 1510
Query: 108 LEDSGTYECRASN-----DPKRNDLRQNPSITWIRAQ--ATISVLQKPRI----VTSEEV 156
+ DSG Y C A+N D N L Q P + A +L + VT
Sbjct: 1511 VSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYRE 1570
Query: 157 IIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNA---SNMEYRINKPRAED 212
I+ ++P L C+ + LT W + LSA + + +I RAE+
Sbjct: 1571 IVENNPAY---LYCDTNAIPPPDLT---WYREDQPLSAGDEVSVLQGGRVLQIPLVRAEN 1624
Query: 213 SGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRS----ENKNEGQDATMYCKSVGYPHP 267
+G Y C + V + + V P I G N ++ C ++G P P
Sbjct: 1625 AGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVP 1684
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASV 327
W +NG+P + S R ++ +++ + D Y C A N GSA
Sbjct: 1685 TISWL--QNGLPF---SPSPRLQVLEDGQVLQVSTAEVA---DAASYMCVAENQAGSAEK 1736
Query: 328 VTVLRVR 334
+ LRV+
Sbjct: 1737 LFTLRVQ 1743
Score = 36.6 bits (83), Expect = 0.040
Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 15/81 (18%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
T + G EL C GSP P IQW R S G +
Sbjct: 509 TTIVGQPLELPCQASGSPVPTIQW--------------LQNGRPAEELAGVQVASQG-TT 553
Query: 101 LRITRLTLEDSGTYECRASND 121
L I + L+ SG + C+A+N+
Sbjct: 554 LHIDHVELDHSGLFACQATNE 574
Score = 34.7 bits (78), Expect = 0.15
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 17/73 (23%)
Query: 259 CKSVGYPHPDWIWRKKEN-----GMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE 313
C + G P P WRK + G P V G F+ + D G+
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVS------------PADSGD 71
Query: 314 YECNATNAIGSAS 326
YEC ATN +GS S
Sbjct: 72 YECQATNEVGSTS 84
Score = 29.6 bits (65), Expect = 4.9
Identities = 20/75 (26%), Positives = 31/75 (41%), Gaps = 24/75 (32%)
Query: 52 CDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE-- 109
C G+P P++ W ++ + +G GV+VL L L
Sbjct: 24 CGTHGTPKPQVTW-------------------RKGPSSEPLHGQPGVAVLEEGSLFLASV 64
Query: 110 ---DSGTYECRASND 121
DSG YEC+A+N+
Sbjct: 65 SPADSGDYECQATNE 79
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 70.5 bits (171), Expect = 3e-12
Identities = 76/312 (24%), Positives = 122/312 (39%), Gaps = 42/312 (13%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F P + GD L C GSPTP I W + R + +G ++
Sbjct: 4131 FTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVND-------RPVTEGVSEQ------- 4176
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
+G S L+ ++ EDSGTY C A N R +A + + V + P ++
Sbjct: 4177 ---DGGSTLQRAAVSREDSGTYVCWAENRVGRT-----------QAVSFVHVKEAP-VLQ 4221
Query: 153 SEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVEL--SATRKNASNMEYRINKPRA 210
E PV ++Q + + +W K+G+ L S R N I++
Sbjct: 4222 GEAFSYLVEPV-GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTER 4280
Query: 211 EDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 269
+D+G Y C+ + + K + +++AP + G D + C++ G P P
Sbjct: 4281 DDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTI 4340
Query: 270 IWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 329
W + G P+ S R + + N+ T D G Y+C A N +GSA+
Sbjct: 4341 EW--LQAGQPL---RASRRLRTLPDGSLWLENVE----TGDAGTYDCVAHNLLGSATARA 4391
Query: 330 VLRVRSHLAPLW 341
L VR W
Sbjct: 4392 FLVVRGEPQGSW 4403
Score = 64.7 bits (156), Expect = 1e-10
Identities = 84/316 (26%), Positives = 123/316 (38%), Gaps = 52/316 (16%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
P+++ L + L C G P P++ W+ + W G VTV+
Sbjct: 1892 PVNKAVLENASVTLECLASGVPPPDVSWF-----KGHQPVSSWMG-----VTVSV----- 1936
Query: 97 GVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEV 156
VLRI + L D+G+Y C ASN +LR + V PRI +
Sbjct: 1937 DGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYG-----------LRVNVPPRITLPPSL 1985
Query: 157 IIRDSPVL---PVTLQCNLTSS-SHTLTYSYWTKNGVELS-----ATRKNASNMEYRINK 207
PVL PV L CN T + S TL W K+G +S + +
Sbjct: 1986 ---PGPVLVNTPVRLTCNATGAPSPTL---MWLKDGNPVSPAGTPGLQVFPGGRVLTLAS 2039
Query: 208 PRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
RA DSG Y CV V + + ++V P I G + + + + + C+S P
Sbjct: 2040 ARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPP 2099
Query: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
P W K +G P++ G +K L V+ D G Y C A N G +
Sbjct: 2100 PVLSWWK--DGRPLE--PRPGVHLSADK----ALLQVDRADVWDAGHYTCEALNQAGHSE 2151
Query: 327 VVTVLRVRSHLAPLWP 342
L V +AP++P
Sbjct: 2152 KHYNLNV--WVAPVFP 2165
Score = 64.3 bits (155), Expect = 2e-10
Identities = 64/302 (21%), Positives = 114/302 (37%), Gaps = 45/302 (14%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G ++ C G PTP I W + + ++ + L I
Sbjct: 622 GVEVKVSCSASGYPTPHISW----------------SRESQALQEDSRIHVDAQGTLIIQ 665
Query: 105 RLTLEDSGTYECRASNDPKRND------LRQNPSITWIRAQATISVLQKPRIVTSEEVII 158
+ ED+G Y C+A+N+ + PS++ + A ++V + E V++
Sbjct: 666 GVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGE-------EAVLV 718
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHC 218
++ +P W + G+E+ + +S+ + RI + D+G Y C
Sbjct: 719 CEASGVPPPRVI-------------WYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTC 765
Query: 219 -VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 277
+ + A + V AP +T R G+ A + C++ G P P WR+ + G
Sbjct: 766 RAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGD-G 824
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHL 337
P+ + +GR + + L ++ ED Y C A N G L V H
Sbjct: 825 QPLGLRLGAGRGSRSRQPDSGVLFFESV-APEDQAPYVCEARNVFGKVQAEARLIVTGHA 883
Query: 338 AP 339
P
Sbjct: 884 PP 885
Score = 63.5 bits (153), Expect = 3e-10
Identities = 68/294 (23%), Positives = 112/294 (38%), Gaps = 33/294 (11%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
P T G + L C G P P + W + G+R R+
Sbjct: 792 PRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG------ 845
Query: 97 GVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVL-QKPRIVTSEE 155
VL + ED Y C A N + ++A+A + V P + S
Sbjct: 846 ---VLFFESVAPEDQAPYVCEARNVFGK-----------VQAEARLIVTGHAPPQIASSA 891
Query: 156 VIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRA--EDS 213
+R PV+L C + + L +W K+G L +++ + ++ RA E +
Sbjct: 892 PTVRVLEGQPVSLPC-IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHA 950
Query: 214 GEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 272
G Y CV + + + + V+ P I NEG A++ C + G P P W
Sbjct: 951 GRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWT 1010
Query: 273 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
K+ N + + G + ++KE ++ +D G Y C ATN +G +S
Sbjct: 1011 KETNAL-----TSRGPHYNVSKEGTL---LIAQPSAQDAGAYVCTATNTVGFSS 1056
Score = 63.5 bits (153), Expect = 3e-10
Identities = 72/288 (25%), Positives = 114/288 (39%), Gaps = 50/288 (17%)
Query: 50 LYCDVVGSPTPEIQWWYAE--VNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLT 107
L C+ +G P P I+W+ E V+ E Y G +L++T+
Sbjct: 2372 LLCEAMGIPPPAIRWFRGEEPVSPGED-----------------TYLLAGGWMLKMTQTQ 2414
Query: 108 LEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSE-EVIIRDSPVLPV 166
+DSG Y C ASN+ + R+N S + VL P I + E +I+
Sbjct: 2415 EQDSGLYSCLASNE--AGEARRNFS---------VEVLVPPSIENEDLEEVIKVLDGQTA 2463
Query: 167 TLQCNLTSSSHTLTYSYWTKNGVELS---ATRKNASNMEYRINKPRAEDSGEYHCV-YHF 222
L CN+T H W K+G L+ A + + ++ + +G Y C+ +
Sbjct: 2464 HLMCNVT--GHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANA 2521
Query: 223 VSAPKANATIEVKAAPDITGHKRSENKNE-----GQDATMYCKSVGYPHPDWIWRKKENG 277
V + + V AP I G E ++ C+++ +P P+ W K +G
Sbjct: 2522 VGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK--DG 2579
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
P + I L I+N Q ED G+Y C TN +G A
Sbjct: 2580 APFEASRN-----IQLLPGTHGLQILNAQ-KEDAGQYTCVVTNELGEA 2621
Score = 62.8 bits (151), Expect = 5e-10
Identities = 60/241 (24%), Positives = 100/241 (41%), Gaps = 37/241 (15%)
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKP-RIV 151
+ +G S I R + + GTYEC A + RA+A I V P ++V
Sbjct: 473 FQESGNSSWEILRASKAEEGTYECTAVSRAGTG-----------RAKAQIVVTDPPPQLV 521
Query: 152 TSEEVIIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRKNAS---NMEYRINK 207
+ V + SP L C L + + LT W ++ L A+ + ++ I+
Sbjct: 522 PAPNVTV--SPGETAVLSCRVLGEAPYNLT---WVRDWRVLPASTGRVAQLADLSLEISG 576
Query: 208 PRAEDSGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
D G Y CV + +A+ + V+ AP ++ H S++ ++G + + C + GYP
Sbjct: 577 IIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPT 636
Query: 267 PDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 323
P W ++ + D V+ G I+ ED G Y C ATN +G
Sbjct: 637 PHISWSRESQALQEDSRIHVDAQGTL------------IIQGVAPEDAGNYSCQATNEVG 684
Query: 324 S 324
+
Sbjct: 685 T 685
Score = 58.9 bits (141), Expect = 8e-09
Identities = 79/298 (26%), Positives = 117/298 (39%), Gaps = 54/298 (18%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE 109
L C G P P + W +++ QL GAR + Y + L I +
Sbjct: 3876 LTCHSTGIPAPTVSW-------SKAGAQL--GAR------GSGYRVSPSGALEIGQALPI 3920
Query: 110 DSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKP---RIVTSEEVIIRDSPVLPV 166
+G Y C A RN ++ QA+ V P R V EEV+
Sbjct: 3921 HAGRYTCSA-----RNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVL--------- 3966
Query: 167 TLQCNLTSSSH-TLTYSYWTKNGVELSA--TRKNASNMEYRINKPRAEDSGEYHCVY-HF 222
L C + T+T W K G+ ++ + + + RI ED+G Y C+ +
Sbjct: 3967 -LPCEASGIPRPTIT---WQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS 4022
Query: 223 VSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDI 282
+ + V+ P I + EG A + CK+ G P P+ W K +G P +
Sbjct: 4023 AGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDK--DGQP--V 4078
Query: 283 VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPL 340
G+F I + EL + NL+ +D G Y C A NA+G A R R HL L
Sbjct: 4079 SGAEGKFTI---QPSGELLVKNLE-GQDAGTYTCTAENAVGRA------RRRVHLTIL 4126
Score = 58.2 bits (139), Expect = 1e-08
Identities = 77/316 (24%), Positives = 118/316 (37%), Gaps = 64/316 (20%)
Query: 19 GSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQL 78
G+LL +AQ+AG + T VG + E++ VNR + +
Sbjct: 1029 GTLLIAQPSAQDAGAYVCTATNT-------------VGFSSQEMR---LSVNRLALSKYV 1072
Query: 79 WDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRA 138
W+ YG LR+ ++ + DSG YEC ASN R +
Sbjct: 1073 WE-----------EYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGV----- 1116
Query: 139 QATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA 198
Q V PR++ +V++ ++ L N + + W+K+GV L
Sbjct: 1117 QVPPQVQPGPRVL---KVLVGEA------LDLNCVAEGNPEPQLSWSKDGVVLQGRGPQG 1167
Query: 199 SNMEYRINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAAPDITGHKRSE--NKNEGQDA 255
S I R D+G Y C + A + V P + S + G++A
Sbjct: 1168 SVHFAAI---RTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENA 1224
Query: 256 TMYCKSVGYPHPDWIWRKKEN-----GMPMDIVNTSGRFFIINKENYTELNIVNLQITED 310
++ C + G P P WRK + G P V G F+ + D
Sbjct: 1225 SLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVS------------PAD 1272
Query: 311 PGEYECNATNAIGSAS 326
G+YEC ATN +GS S
Sbjct: 1273 SGDYECQATNEVGSTS 1288
Score = 55.8 bits (133), Expect = 6e-08
Identities = 72/302 (23%), Positives = 114/302 (37%), Gaps = 50/302 (16%)
Query: 49 ELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTL 108
+L C+ G PTP I W+ DGA T Y + G L++ R
Sbjct: 1521 QLLCEARGVPTPNITWFK-------------DGALLPTST-KVVY-TRGGRQLQLGRAQS 1565
Query: 109 EDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI--VTSEEVIIRDSPVLPV 166
D+G Y C+ASN ++ + V P I +++ PV
Sbjct: 1566 SDAGVYTCKASN-----------AVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPV 1614
Query: 167 TLQCNLTSSSHTLTYSYWTKNGV---ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFV 223
L+C + H W G+ E + +R R+ P SG Y CV
Sbjct: 1615 ALEC--VARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV---A 1669
Query: 224 SAPKANA----TIEVKAAPDITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKENG 277
S+P A ++EV+ P + + GQ + C++ G P P W +NG
Sbjct: 1670 SSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL--QNG 1727
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHL 337
P + +G + T L+I ++++ + G + C ATN G+A + V
Sbjct: 1728 RPAE--ELAG---VQVASQGTTLHIDHVEL-DHSGLFACQATNEAGTAGAEVEVSVHGEW 1781
Query: 338 AP 339
AP
Sbjct: 1782 AP 1783
Score = 55.8 bits (133), Expect = 6e-08
Identities = 75/302 (24%), Positives = 116/302 (38%), Gaps = 51/302 (16%)
Query: 39 SETKLT-GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNG 97
+E LT G EL CD G+P P I W DG R+ N S
Sbjct: 3503 TELSLTPGAPMELLCDAQGTPQPNITWHK-------------DGQALTRLENN----SRA 3545
Query: 98 VSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVL--QKPRIVTSEE 155
VLR+ D+G Y C A + + +R QA +++ + PR V
Sbjct: 3546 TRVLRV-----RDAGLYTCLAESPAGAIEKSFR-----VRVQAPPNIVGPRGPRFVVG-- 3593
Query: 156 VIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRA---ED 212
+ P L + + W ++G+ L R + +A D
Sbjct: 3594 -------LAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTAD 3646
Query: 213 SGEYHCVYHFVSAPKANA-TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIW 271
SG+Y C + + A +E+ P I + N + Q A + C++ G P P W
Sbjct: 3647 SGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW 3706
Query: 272 RKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 331
RK + +P+D S RF I+ + + + + +D G Y C A+N+ GS L
Sbjct: 3707 RK--DRVPLD--PRSPRFEILPEGSLR----IQPVLAQDAGHYLCLASNSAGSDRQGRDL 3758
Query: 332 RV 333
RV
Sbjct: 3759 RV 3760
Score = 53.9 bits (128), Expect = 2e-07
Identities = 78/302 (25%), Positives = 119/302 (39%), Gaps = 63/302 (20%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
L G L C+V G P P++ W+ DG R + +GV +L+
Sbjct: 2458 LDGQTAHLMCNVTGHPQPKLTWFK-------------DGRPLARGDAH-HISPDGV-LLQ 2502
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV------TSEEV 156
+ + L +G Y C A+N ++ +SVL P I+ EEV
Sbjct: 2503 VLQANLSSAGHYSCIAAN-----------AVGEKTKHFQLSVLLAPTILGGAEDSADEEV 2551
Query: 157 IIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRK---NASNMEYRINKPRAED 212
+ + P++L C L S +T W K+G A+R +I + ED
Sbjct: 2552 TVTVNN--PISLICEALAFPSPNIT---WMKDGAPFEASRNIQLLPGTHGLQILNAQKED 2606
Query: 213 SGEYHCVY-HFVSAPKANATIEVKAAPDIT--------GHKRSENKNEGQDATMYCKSVG 263
+G+Y CV + + N +EV P I+ G K + K T+ C+S
Sbjct: 2607 AGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTK-VNSTLTLECESWA 2665
Query: 264 YPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE--DPGEYECNATNA 321
P P W K +G P V S R ++ E ++ +Q T+ D G Y C ATN
Sbjct: 2666 VPPPTIRWYK--DGQP---VTPSSRLQVLG-----EGRLLQIQPTQVSDSGRYLCVATNV 2715
Query: 322 IG 323
G
Sbjct: 2716 AG 2717
Score = 52.4 bits (124), Expect = 7e-07
Identities = 63/292 (21%), Positives = 113/292 (38%), Gaps = 44/292 (15%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE 109
LYCD P P++ W +R+ + V+V G VL+I + E
Sbjct: 2770 LYCDTNAIPPPDLTW----------YREDQPLSAGDEVSV-----LQGGRVLQIPLVRAE 2814
Query: 110 DSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPV---LPV 166
++G Y C+ASN+ + W+ + + VL P I+ E ++ + V V
Sbjct: 2815 NAGRYSCKASNEVGED---------WLHYE--LLVLTPPVILGDTEELVEEVTVNASSTV 2863
Query: 167 TLQCNLTSSSHTLTYSYWTKNGVELSATRK---NASNMEYRINKPRAEDSGEYHCV-YHF 222
+LQC + + + W +NG+ S + + +++ D+ Y CV +
Sbjct: 2864 SLQC--PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQ 2921
Query: 223 VSAPKANATIEVKAAPDITGHKRSE-NKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMD 281
+ + T+ V+ P I G + ++ C +P+P+ W K + +
Sbjct: 2922 AGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSL- 2980
Query: 282 IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
F++ + +L L D G Y C A NA G + L V
Sbjct: 2981 ----GEEVFLLPGTHTLQLGRARL---SDSGMYTCEALNAAGRDQKLVQLSV 3025
Score = 50.1 bits (118), Expect = 4e-06
Identities = 74/320 (23%), Positives = 120/320 (37%), Gaps = 58/320 (18%)
Query: 15 LLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAES 74
+LV + P Q+A V+ GD L C+ P P + W+
Sbjct: 3025 VLVPPAFRQAPRGPQDAVLVR--------VGDKAVLSCETDALPEPTVTWYK-------- 3068
Query: 75 FRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSIT 134
DG + V G L I + D G Y C+ SN
Sbjct: 3069 -----DG--QPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSN-------------- 3107
Query: 135 WIRAQA----TISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNG- 188
+ +A T++V P + + P+ L C+++ + T+T W K+
Sbjct: 3108 -VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVT---WLKDRM 3163
Query: 189 -VELSATRKNASNM-EYRINKPRAEDSGEYHCVYHFVSAP-KANATIEVKAAPDI--TGH 243
VE SA S ++++ + +G Y CV A + + + V AP I +G
Sbjct: 3164 PVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGV 3223
Query: 244 KRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIV 303
R + EGQ+ + C++ G P PD W K + + D + RF++ + L +
Sbjct: 3224 AREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQD-MGPHLRFYL----DGGSLVLK 3278
Query: 304 NLQITEDPGEYECNATNAIG 323
L+ D G Y C A N G
Sbjct: 3279 GLR-ASDAGAYTCVAHNPAG 3297
Score = 50.1 bits (118), Expect = 4e-06
Identities = 71/302 (23%), Positives = 114/302 (37%), Gaps = 56/302 (18%)
Query: 45 GDAFELYCDVVGSPTPEIQWWY-AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRI 103
G EL C+ G P P + W E ++S Q G S L++
Sbjct: 3421 GSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQ-------------------GPS-LQL 3460
Query: 104 TRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS-EEVIIRDSP 162
+ DSGTY C A ++ R ++V++ P I S + + +P
Sbjct: 3461 EAVGAGDSGTYSCVAVSEAGE-----------ARRHFQLTVMEPPHIEDSGQPTELSLTP 3509
Query: 163 VLPVTLQCNLTSSSH-TLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYH 221
P+ L C+ + +T W K+G L+ N+ R D+G Y C+
Sbjct: 3510 GAPMELLCDAQGTPQPNIT---WHKDGQALTRLENNSRATRVL----RVRDAGLYTCLAE 3562
Query: 222 F-VSAPKANATIEVKAAPDITGHKRSE---NKNEGQDATMYCKSVGYPHPDWIWRKKENG 277
A + + + V+A P+I G + GQ + C P P W + +G
Sbjct: 3563 SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQ-LVLECSVEAEPAPKITWHR--DG 3619
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHL 337
+ ++ + + +L ++ T D G+Y C A NA GS SV RV H
Sbjct: 3620 I---VLQEDAHTQFPERGRFLQLQALS---TADSGDYSCTARNAAGSTSV--AFRVEIHT 3671
Query: 338 AP 339
P
Sbjct: 3672 VP 3673
Score = 49.7 bits (117), Expect = 5e-06
Identities = 75/318 (23%), Positives = 111/318 (34%), Gaps = 67/318 (21%)
Query: 43 LTGDAFELYCDVVGSPTPEIQW-----------------WYAEVNRAESFRQLWDGARKR 85
+ G + L CD G P PEI W W + R L +G
Sbjct: 1313 MAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS-- 1370
Query: 86 RVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVL 145
L R+ DSG Y CRA N + + VL
Sbjct: 1371 ---------------LHFPRIQEGDSGLYSCRAENQAGT-----------AQRDFHLLVL 1404
Query: 146 QKPRIV---TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME 202
P ++ ++EV+ V LQC +S WTK+ + + E
Sbjct: 1405 TPPSVLGAGAAQEVL--GLAGADVELQC--WTSGVPTPQVEWTKDRQPVLPGGPHLQVQE 1460
Query: 203 ----YRINKPRAEDSGEYHCVYHFVSAPKA-NATIEVKAAPDITGHKRSENKNEGQD--A 255
RI D G Y CV + +A + + V A P I G + +D
Sbjct: 1461 DGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLV 1520
Query: 256 TMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYE 315
+ C++ G P P+ W K +P TS + ++ +L + Q + D G Y
Sbjct: 1521 QLLCEARGVPTPNITWFKDGALLP-----TSTK--VVYTRGGRQLQLGRAQ-SSDAGVYT 1572
Query: 316 CNATNAIGSASVVTVLRV 333
C A+NA+G+A T L V
Sbjct: 1573 CKASNAVGAAEKATRLDV 1590
Score = 47.4 bits (111), Expect = 2e-05
Identities = 69/312 (22%), Positives = 113/312 (36%), Gaps = 58/312 (18%)
Query: 36 SPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGS 95
SP + T L C+ GSP P + WW DG + AY
Sbjct: 3769 SPSNLTLTAHTPALLPCEASGSPKPLVVWWK-------------DGQKLDFRLQQGAYRL 3815
Query: 96 NGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEE 155
+ L +T +DS +EC SN+ Q T+ V P + ++
Sbjct: 3816 LPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLY---------QVTVHV---PPTIADDQ 3863
Query: 156 VIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAED-- 212
+ + PV L C+ T + T++ W+K G +L A YR++ A +
Sbjct: 3864 TDFTVTMMAPVVLTCHSTGIPAPTVS---WSKAGAQLGARGSG-----YRVSPSGALEIG 3915
Query: 213 ------SGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 265
+G Y C + + + V+A+P + ++ + C++ G P
Sbjct: 3916 QALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIP 3975
Query: 266 HPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 322
P W+K+ + + V G+ I + ED G Y C A N+
Sbjct: 3976 RPTITWQKEGLNVATGVSTQVLPGGQLRIAHAS------------PEDAGNYLCIAKNSA 4023
Query: 323 GSASVVTVLRVR 334
GSA T L V+
Sbjct: 4024 GSAMGKTRLVVQ 4035
Score = 46.2 bits (108), Expect = 5e-05
Identities = 74/307 (24%), Positives = 114/307 (37%), Gaps = 46/307 (14%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
T + + L CDV P PE+ W+ + ++A S + + G
Sbjct: 2948 TAILNSSVSLPCDVHAHPNPEVTWY--KDSQALSLGE-------------EVFLLPGTHT 2992
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRD 160
L++ R L DSG Y C A N R+ + + + Q PR + V++R
Sbjct: 2993 LQLGRARLSDSGMYTCEALNAAGRDQ-----KLVQLSVLVPPAFRQAPR-GPQDAVLVRV 3046
Query: 161 SPVLPVTLQCNLTS-SSHTLTYSYWTKNGVEL---SATRKNASNMEYRINKPRAEDSGEY 216
L C + T+T W K+G L T+ I + + D G Y
Sbjct: 3047 GD--KAVLSCETDALPEPTVT---WYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLY 3101
Query: 217 HCVYHFVSAPKANA-TIEVKAAPDITGHK-RSENKNEGQDATMYCKSVGYPHPDWIWRKK 274
C V+ T+ V+ P K + ++ G + C G P P W K
Sbjct: 3102 SCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLK- 3160
Query: 275 ENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS---VVTVL 331
+ MP V +S ++++ L + LQ + G Y C A N A VV VL
Sbjct: 3161 -DRMP---VESSAVHGVVSRGG--RLQLSRLQPAQ-AGTYTCVAENTQAEARKDFVVAVL 3213
Query: 332 ---RVRS 335
R+RS
Sbjct: 3214 VAPRIRS 3220
Score = 45.4 bits (106), Expect = 9e-05
Identities = 74/324 (22%), Positives = 122/324 (37%), Gaps = 60/324 (18%)
Query: 14 LLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAE 73
LL+++ + G GAAQ L G EL C G PTP+++W +
Sbjct: 1401 LLVLTPPSVLGAGAAQEV---------LGLAGADVELQCWTSGVPTPQVEW-------TK 1444
Query: 74 SFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSI 133
+ + G +V VLRIT + D G Y+C A + P R
Sbjct: 1445 DRQPVLPGGPHLQV-------QEDGQVLRITGSHVGDEGRYQCVAFS-PAGQQARD---- 1492
Query: 134 TWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSA 193
+R A ++ T E ++ D V + + + + T W K+G L
Sbjct: 1493 FQLRVHAPPTIWGSNE--TGEVAVMEDHLVQLLCEARGVPTPNIT-----WFKDGALLPT 1545
Query: 194 TRK---NASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDIT---GHKRS 246
+ K + ++ + ++ D+G Y C + V A + ++V P I G
Sbjct: 1546 STKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYV 1605
Query: 247 ENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQ 306
G+ + C + G+P P W G+P+ N S T+ +++ L
Sbjct: 1606 VKAVAGRPVALECVARGHPSPTLSWH--HEGLPVAESNES--------RLETDGSVLRL- 1654
Query: 307 ITEDPGE-----YECNATNAIGSA 325
E PGE Y C A++ G A
Sbjct: 1655 --ESPGEASSGLYSCVASSPAGEA 1676
Score = 45.4 bits (106), Expect = 9e-05
Identities = 65/312 (20%), Positives = 107/312 (34%), Gaps = 60/312 (19%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
L L C+ G+P+P + W L DG G VL
Sbjct: 1990 LVNTPVRLTCNATGAPSPTLMW-------------LKDGNPVSPAGTPGLQVFPGGRVLT 2036
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSE---EVIIR 159
+ DSG Y C A + ++ R + V P I+ E V+
Sbjct: 2037 LASARASDSGRYSCVAVS-----------AVGEDRQDVVLQVHMPPSILGEELNVSVVAN 2085
Query: 160 DSPVLPVTLQCNLTSSSHTLTYSY--WTKNGVELS---ATRKNASNMEYRINKPRAEDSG 214
+S V L+C SH + W K+G L +A ++++ D+G
Sbjct: 2086 ES----VALECQ----SHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAG 2137
Query: 215 EYHC-VYHFVSAPKANATIEVKAAPDIT-GHKRSENKNEGQDATMYCKSVGYPHPDWIWR 272
Y C + + + + V AP + EG ++ C+ G P P WR
Sbjct: 2138 HYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWR 2197
Query: 273 KKENGMP-----MDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASV 327
K +P + V+ GR + + + G Y C +N +G++S
Sbjct: 2198 KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQ-----------EGTYTCECSNVVGNSS- 2245
Query: 328 VTVLRVRSHLAP 339
L++ H+ P
Sbjct: 2246 -QDLQLEVHVPP 2256
Score = 42.7 bits (99), Expect = 6e-04
Identities = 70/304 (23%), Positives = 110/304 (36%), Gaps = 61/304 (20%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
L G+A +L C G+P P++ W DG G +
Sbjct: 1132 LVGEALDLNCVAEGNPEPQLSWSK-------------DGV--------VLQGRGPQGSVH 1170
Query: 103 ITRLTLEDSGTYECRASN----DPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVII 158
+ D+G Y C ASN D +LR W A T +L++ V E +
Sbjct: 1171 FAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHW-GADETSGLLER---VAGENASL 1226
Query: 159 ----RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSG 214
R +P VT + +S +G A + S ++ DSG
Sbjct: 1227 PCPARGTPKPQVTWRKGPSSEP---------LHGQPGVAVLEEGSLFLASVSPA---DSG 1274
Query: 215 EYHC-VYHFVSAPKANATIEVKAAPDIT--GHKRSENKNEGQDATMYCKSVGYPHPDWIW 271
+Y C + V + A + V P I G K + + GQ T+ C + G+P P+ +W
Sbjct: 1275 DYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVW 1334
Query: 272 RKKEN--GMPMDIVNTS--------GRFFIINKENYTELNIVNLQITEDPGEYECNATNA 321
K G+P+ G ++++ L+ +Q D G Y C A N
Sbjct: 1335 LKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQ--SLHFPRIQ-EGDSGLYSCRAENQ 1391
Query: 322 IGSA 325
G+A
Sbjct: 1392 AGTA 1395
Score = 41.2 bits (95), Expect = 0.002
Identities = 57/251 (22%), Positives = 91/251 (36%), Gaps = 41/251 (16%)
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS--EEVII 158
L+I ++ L D G Y C A+N + + + + VL P I + ++
Sbjct: 1850 LQIEKVDLRDEGIYTCAATNLAGES-----------KREVALKVLVPPNIEPGPVNKAVL 1898
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSA---TRKNASNMEYRINKPRAEDSGE 215
++ VTL+C L S S W K +S+ + RI + + D+G
Sbjct: 1899 ENA---SVTLEC-LASGVPPPDVS-WFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGS 1953
Query: 216 YHCVYHFVSAP-------KANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPD 268
Y CV V+ + N + P + G + C + G P P
Sbjct: 1954 YRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNT-----PVRLTCNATGAPSPT 2008
Query: 269 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 328
+W K +G P+ T G T + D G Y C A +A+G
Sbjct: 2009 LMWLK--DGNPVSPAGTPGLQVFPGGRVLT----LASARASDSGRYSCVAVSAVGEDRQD 2062
Query: 329 TVLRVRSHLAP 339
VL+V H+ P
Sbjct: 2063 VVLQV--HMPP 2071
Score = 40.0 bits (92), Expect = 0.004
Identities = 62/292 (21%), Positives = 105/292 (35%), Gaps = 45/292 (15%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
+ ++ L C P P + WW + R L + R V+ S ++L+
Sbjct: 2083 VANESVALECQSHAMPPPVLSWW-------KDGRPL-----EPRPGVHL---SADKALLQ 2127
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
+ R + D+G Y C A N ++ N ++ W+ A + L++ +T E
Sbjct: 2128 VDRADVWDAGHYTCEALNQAGHSEKHYNLNV-WV---APVFPLRESHTLTVREGH----- 2178
Query: 163 VLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME-----YRINKPRAEDSGEYH 217
P +L C W K+G L ++ + + + G Y
Sbjct: 2179 --PTSLSCECRGVPFPKIS--WRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYT 2234
Query: 218 C-VYHFVSAPKANATIEVKAAPDITGHKRSENK-NEGQD--ATMYCKSVGYPHPDWIWRK 273
C + V + +EV P I G + + + QD AT+ C + G P P W +
Sbjct: 2235 CECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWER 2294
Query: 274 KENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
+G P+ G + +N + V G Y C A N G A
Sbjct: 2295 --DGQPV------GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRA 2338
Score = 40.0 bits (92), Expect = 0.004
Identities = 52/232 (22%), Positives = 84/232 (36%), Gaps = 31/232 (13%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G+ + C V GSP + W L DG +GS LRI+
Sbjct: 3328 GELVTMVCPVRGSPPIHVSW-------------LKDGLPLPLSQRTLLHGSG--HTLRIS 3372
Query: 105 RLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVL 164
++ L D+G + C A++ D Q + + +P ++ V++R S
Sbjct: 3373 KVQLADAGIFTCVAASPAGVADRN-------FTLQVQVPPVLEPVEFQNDVVVVRGS--- 3422
Query: 165 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCV-YHFV 223
V L C + L W K+G L ++ ++ A DSG Y CV
Sbjct: 3423 LVELPCE--ARGVPLPLVSWMKDGEPL-LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEA 3479
Query: 224 SAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRK 273
+ + + V P I +G + G + C + G P P+ W K
Sbjct: 3480 GEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHK 3531
Score = 39.7 bits (91), Expect = 0.005
Identities = 65/319 (20%), Positives = 112/319 (35%), Gaps = 78/319 (24%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGAR-KRRVTVNTAYGSNGVS 99
T + L C+ + P+P I W + DGA + + G++G+
Sbjct: 2552 TVTVNNPISLICEALAFPSPNITW-------------MKDGAPFEASRNIQLLPGTHGLQ 2598
Query: 100 VLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIR 159
+L + ED+G Y C +N+ + + VL P I +
Sbjct: 2599 ILNAQK---EDAGQYTCVVTNELGEAVKNYH-----------VEVLIPPSIS-------K 2637
Query: 160 DSPVLPVTLQCNLTSSSHTLTYSY-----------WTKNGVELSATRKNASNMEYR---I 205
D P+ V ++ T + TLT W K+G ++ + + E R I
Sbjct: 2638 DDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQI 2697
Query: 206 NKPRAEDSGEYHCVYHFVSAPKA---NATIEV----------KAAPDITGHKRSENKN-- 250
+ DSG Y CV V+ N I+V AA +I +
Sbjct: 2698 QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVT 2757
Query: 251 ------EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVN 304
E A +YC + P PD W +++ + + ++ ++ +V
Sbjct: 2758 EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPL-----SAGDEVSVLQGGRVLQIPLVR 2812
Query: 305 LQITEDPGEYECNATNAIG 323
E+ G Y C A+N +G
Sbjct: 2813 ---AENAGRYSCKASNEVG 2828
Score = 37.0 bits (84), Expect = 0.031
Identities = 71/307 (23%), Positives = 113/307 (36%), Gaps = 53/307 (17%)
Query: 50 LYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLT 107
L C+ P P I+W+ V + + L +G +L+I
Sbjct: 2659 LECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGR-----------------LLQIQPTQ 2701
Query: 108 LEDSGTYECRASN-----DPKRNDLRQNPSITWIRAQ--ATISVLQKPRI----VTSEEV 156
+ DSG Y C A+N D N L Q P + A +L + VT
Sbjct: 2702 VSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYRE 2761
Query: 157 IIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNA---SNMEYRINKPRAED 212
I+ ++P L C+ + LT W + LSA + + +I RAE+
Sbjct: 2762 IVENNPAY---LYCDTNAIPPPDLT---WYREDQPLSAGDEVSVLQGGRVLQIPLVRAEN 2815
Query: 213 SGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRS----ENKNEGQDATMYCKSVGYPHP 267
+G Y C + V + + V P I G N ++ C ++G P P
Sbjct: 2816 AGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVP 2875
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASV 327
W +NG+P + S R ++ +++ + D Y C A N GSA
Sbjct: 2876 TISWL--QNGLPF---SPSPRLQVLEDGQVLQVSTAEVA---DAASYMCVAENQAGSAEK 2927
Query: 328 VTVLRVR 334
+ LRV+
Sbjct: 2928 LFTLRVQ 2934
Score = 36.6 bits (83), Expect = 0.040
Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 15/81 (18%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
T + G EL C GSP P IQW R S G +
Sbjct: 1700 TTIVGQPLELPCQASGSPVPTIQW--------------LQNGRPAEELAGVQVASQG-TT 1744
Query: 101 LRITRLTLEDSGTYECRASND 121
L I + L+ SG + C+A+N+
Sbjct: 1745 LHIDHVELDHSGLFACQATNE 1765
Score = 34.3 bits (77), Expect = 0.20
Identities = 34/134 (25%), Positives = 50/134 (37%), Gaps = 21/134 (15%)
Query: 204 RINKPRAEDSGEYHCVYHFVSAPKANAT----IEVKAAPDITGHKRSENKNEGQDATMYC 259
R+ + + DSG Y C S P +A+ + V+ P + R G+ + C
Sbjct: 1085 RLAQVQVGDSGHYECT---ASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNC 1141
Query: 260 KSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 319
+ G P P W K D V GR + + T D G Y C A+
Sbjct: 1142 VAEGNPEPQLSWSK-------DGVVLQGR----GPQGSVHFAAIR---TSDAGRYRCEAS 1187
Query: 320 NAIGSASVVTVLRV 333
N+ G + LRV
Sbjct: 1188 NSAGVDAWEVELRV 1201
Score = 29.3 bits (64), Expect = 6.5
Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 17/144 (11%)
Query: 196 KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQD 254
+ + N + I + + G Y C +A A I V P + + G+
Sbjct: 474 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGET 533
Query: 255 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----ED 310
A + C+ +G + W + +P ++GR +L ++L+I+ D
Sbjct: 534 AVLSCRVLGEAPYNLTWVRDWRVLPA----STGRV--------AQLADLSLEISGIIPTD 581
Query: 311 PGEYECNATNAIGSASVVTVLRVR 334
G Y+C A+NA G L VR
Sbjct: 582 GGRYQCVASNANGVTRASVWLLVR 605
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 70.1 bits (170), Expect = 3e-12
Identities = 76/312 (24%), Positives = 121/312 (38%), Gaps = 42/312 (13%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F P + GD L C GSPTP I W + R + +G ++
Sbjct: 2849 FTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVND-------RPVTEGVSEQ------- 2894
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
+G S L+ ++ EDSGTY C A N R +A + + V + P ++
Sbjct: 2895 ---DGGSTLQRAAVSREDSGTYVCWAENRVGRT-----------QAVSFVHVKEAP-VLQ 2939
Query: 153 SEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVEL--SATRKNASNMEYRINKPRA 210
E PV ++Q + + +W K+G+ L S R N I +
Sbjct: 2940 GEAFSYLVEPV-GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTER 2998
Query: 211 EDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDW 269
+D+G Y C+ + + K + +++AP + G D + C++ G P P
Sbjct: 2999 DDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTI 3058
Query: 270 IWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 329
W + G P+ S R + + N+ T D G Y+C A N +GSA+
Sbjct: 3059 EW--LQAGQPL---RASRRLRTLPDGSLWLENVE----TGDAGTYDCVAHNLLGSATARA 3109
Query: 330 VLRVRSHLAPLW 341
L VR W
Sbjct: 3110 FLVVRGEPQGSW 3121
Score = 64.7 bits (156), Expect = 1e-10
Identities = 84/316 (26%), Positives = 123/316 (38%), Gaps = 52/316 (16%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
P+++ L + L C G P P++ W+ + W G VTV+
Sbjct: 610 PVNKAVLENASVTLECLASGVPPPDVSWF-----KGHQPVSSWMG-----VTVSV----- 654
Query: 97 GVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEV 156
VLRI + L D+G+Y C ASN +LR + V PRI +
Sbjct: 655 DGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYG-----------LRVNVPPRITLPPSL 703
Query: 157 IIRDSPVL---PVTLQCNLTSS-SHTLTYSYWTKNGVELS-----ATRKNASNMEYRINK 207
PVL PV L CN T + S TL W K+G +S + +
Sbjct: 704 ---PGPVLVNTPVRLTCNATGAPSPTL---MWLKDGNPVSPAGTPGLQVFPGGRVLTLAS 757
Query: 208 PRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
RA DSG Y CV V + + ++V P I G + + + + + C+S P
Sbjct: 758 ARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPP 817
Query: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
P W K +G P++ G +K L V+ D G Y C A N G +
Sbjct: 818 PVLSWWK--DGRPLE--PRPGVHLSADK----ALLQVDRADVWDAGHYTCEALNQAGHSE 869
Query: 327 VVTVLRVRSHLAPLWP 342
L V +AP++P
Sbjct: 870 KHYNLNV--WVAPVFP 883
Score = 63.5 bits (153), Expect = 3e-10
Identities = 72/288 (25%), Positives = 114/288 (39%), Gaps = 50/288 (17%)
Query: 50 LYCDVVGSPTPEIQWWYAE--VNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLT 107
L C+ +G P P I+W+ E V+ E Y G +L++T+
Sbjct: 1090 LLCEAMGIPPPAIRWFRGEEPVSPGED-----------------TYLLAGGWMLKMTQTQ 1132
Query: 108 LEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSE-EVIIRDSPVLPV 166
+DSG Y C ASN+ + R+N S + VL P I + E +I+
Sbjct: 1133 EQDSGLYSCLASNE--AGEARRNFS---------VEVLVPPSIENEDLEEVIKVLDGQTA 1181
Query: 167 TLQCNLTSSSHTLTYSYWTKNGVELS---ATRKNASNMEYRINKPRAEDSGEYHCV-YHF 222
L CN+T H W K+G L+ A + + ++ + +G Y C+ +
Sbjct: 1182 HLMCNVT--GHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANA 1239
Query: 223 VSAPKANATIEVKAAPDITGHKRSENKNE-----GQDATMYCKSVGYPHPDWIWRKKENG 277
V + + V AP I G E ++ C+++ +P P+ W K +G
Sbjct: 1240 VGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMK--DG 1297
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
P + I L I+N Q ED G+Y C TN +G A
Sbjct: 1298 APFEASRN-----IQLLPGTHGLQILNAQ-KEDAGQYTCVVTNELGEA 1339
Score = 58.9 bits (141), Expect = 8e-09
Identities = 79/298 (26%), Positives = 117/298 (39%), Gaps = 54/298 (18%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE 109
L C G P P + W +++ QL GAR + Y + L I +
Sbjct: 2594 LTCHSTGIPAPTVSW-------SKAGAQL--GAR------GSGYRVSPSGALEIGQALPI 2638
Query: 110 DSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKP---RIVTSEEVIIRDSPVLPV 166
+G Y C A RN ++ QA+ V P R V EEV+
Sbjct: 2639 HAGRYTCSA-----RNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVL--------- 2684
Query: 167 TLQCNLTSSSH-TLTYSYWTKNGVELSA--TRKNASNMEYRINKPRAEDSGEYHCVY-HF 222
L C + T+T W K G+ ++ + + + RI ED+G Y C+ +
Sbjct: 2685 -LPCEASGIPRPTIT---WQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNS 2740
Query: 223 VSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDI 282
+ + V+ P I + EG A + CK+ G P P+ W K +G P +
Sbjct: 2741 AGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDK--DGQP--V 2796
Query: 283 VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAPL 340
G+F I + EL + NL+ +D G Y C A NA+G A R R HL L
Sbjct: 2797 SGAEGKFTI---QPSGELLVKNLE-GQDAGTYTCTAENAVGRA------RRRVHLTIL 2844
Score = 55.8 bits (133), Expect = 6e-08
Identities = 72/302 (23%), Positives = 114/302 (37%), Gaps = 50/302 (16%)
Query: 49 ELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTL 108
+L C+ G PTP I W+ DGA T Y + G L++ R
Sbjct: 239 QLLCEARGVPTPNITWFK-------------DGALLPTST-KVVY-TRGGRQLQLGRAQS 283
Query: 109 EDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI--VTSEEVIIRDSPVLPV 166
D+G Y C+ASN ++ + V P I +++ PV
Sbjct: 284 SDAGVYTCKASN-----------AVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPV 332
Query: 167 TLQCNLTSSSHTLTYSYWTKNGV---ELSATRKNASNMEYRINKPRAEDSGEYHCVYHFV 223
L+C + H W G+ E + +R R+ P SG Y CV
Sbjct: 333 ALEC--VARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCV---A 387
Query: 224 SAPKANA----TIEVKAAPDITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKENG 277
S+P A ++EV+ P + + GQ + C++ G P P W +NG
Sbjct: 388 SSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL--QNG 445
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHL 337
P + +G + T L+I ++++ + G + C ATN G+A + V
Sbjct: 446 RPAE--ELAG---VQVASQGTTLHIDHVEL-DHSGLFACQATNEAGTAGAEVEVSVHGEW 499
Query: 338 AP 339
AP
Sbjct: 500 AP 501
Score = 55.8 bits (133), Expect = 6e-08
Identities = 75/302 (24%), Positives = 116/302 (38%), Gaps = 51/302 (16%)
Query: 39 SETKLT-GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNG 97
+E LT G EL CD G+P P I W DG R+ N S
Sbjct: 2221 TELSLTPGAPMELLCDAQGTPQPNITWHK-------------DGQALTRLENN----SRA 2263
Query: 98 VSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVL--QKPRIVTSEE 155
VLR+ D+G Y C A + + +R QA +++ + PR V
Sbjct: 2264 TRVLRV-----RDAGLYTCLAESPAGAIEKSFR-----VRVQAPPNIVGPRGPRFVVG-- 2311
Query: 156 VIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRA---ED 212
+ P L + + W ++G+ L R + +A D
Sbjct: 2312 -------LAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTAD 2364
Query: 213 SGEYHCVYHFVSAPKANA-TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIW 271
SG+Y C + + A +E+ P I + N + Q A + C++ G P P W
Sbjct: 2365 SGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSW 2424
Query: 272 RKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVL 331
RK + +P+D S RF I+ + + + + +D G Y C A+N+ GS L
Sbjct: 2425 RK--DRVPLD--PRSPRFEILPEGSLR----IQPVLAQDAGHYLCLASNSAGSDRQGRDL 2476
Query: 332 RV 333
RV
Sbjct: 2477 RV 2478
Score = 53.9 bits (128), Expect = 2e-07
Identities = 78/302 (25%), Positives = 119/302 (39%), Gaps = 63/302 (20%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
L G L C+V G P P++ W+ DG R + +GV +L+
Sbjct: 1176 LDGQTAHLMCNVTGHPQPKLTWFK-------------DGRPLARGDAH-HISPDGV-LLQ 1220
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV------TSEEV 156
+ + L +G Y C A+N ++ +SVL P I+ EEV
Sbjct: 1221 VLQANLSSAGHYSCIAAN-----------AVGEKTKHFQLSVLLAPTILGGAEDSADEEV 1269
Query: 157 IIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRK---NASNMEYRINKPRAED 212
+ + P++L C L S +T W K+G A+R +I + ED
Sbjct: 1270 TVTVNN--PISLICEALAFPSPNIT---WMKDGAPFEASRNIQLLPGTHGLQILNAQKED 1324
Query: 213 SGEYHCVY-HFVSAPKANATIEVKAAPDIT--------GHKRSENKNEGQDATMYCKSVG 263
+G+Y CV + + N +EV P I+ G K + K T+ C+S
Sbjct: 1325 AGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTK-VNSTLTLECESWA 1383
Query: 264 YPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE--DPGEYECNATNA 321
P P W K +G P V S R ++ E ++ +Q T+ D G Y C ATN
Sbjct: 1384 VPPPTIRWYK--DGQP---VTPSSRLQVLG-----EGRLLQIQPTQVSDSGRYLCVATNV 1433
Query: 322 IG 323
G
Sbjct: 1434 AG 1435
Score = 52.4 bits (124), Expect = 7e-07
Identities = 63/292 (21%), Positives = 113/292 (38%), Gaps = 44/292 (15%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE 109
LYCD P P++ W +R+ + V+V G VL+I + E
Sbjct: 1488 LYCDTNAIPPPDLTW----------YREDQPLSAGDEVSV-----LQGGRVLQIPLVRAE 1532
Query: 110 DSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPV---LPV 166
++G Y C+ASN+ + W+ + + VL P I+ E ++ + V V
Sbjct: 1533 NAGRYSCKASNEVGED---------WLHYE--LLVLTPPVILGDTEELVEEVTVNASSTV 1581
Query: 167 TLQCNLTSSSHTLTYSYWTKNGVELSATRK---NASNMEYRINKPRAEDSGEYHCV-YHF 222
+LQC + + + W +NG+ S + + +++ D+ Y CV +
Sbjct: 1582 SLQC--PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQ 1639
Query: 223 VSAPKANATIEVKAAPDITGHKRSE-NKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMD 281
+ + T+ V+ P I G + ++ C +P+P+ W K + +
Sbjct: 1640 AGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSL- 1698
Query: 282 IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
F++ + +L L D G Y C A NA G + L V
Sbjct: 1699 ----GEEVFLLPGTHTLQLGRARL---SDSGMYTCEALNAAGRDQKLVQLSV 1743
Score = 50.1 bits (118), Expect = 4e-06
Identities = 81/346 (23%), Positives = 124/346 (35%), Gaps = 72/346 (20%)
Query: 15 LLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQW---------- 64
LL +GS++P P ++ + + + G + L CD G P PEI W
Sbjct: 8 LLNTGSVVP-PSIREDG----RKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVP 62
Query: 65 -------WYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECR 117
W + R L +G L R+ DSG Y CR
Sbjct: 63 LGWAGYGWDLGWGQVGGHRLLDEGQS-----------------LHFPRIQEGDSGLYSCR 105
Query: 118 ASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV---TSEEVIIRDSPVLPVTLQCNLTS 174
A N + + VL P ++ ++EV+ V LQC +
Sbjct: 106 AENQAGT-----------AQRDFHLLVLTPPSVLGAGAAQEVL--GLAGADVELQC--WT 150
Query: 175 SSHTLTYSYWTKNGVELSATRKNASNME----YRINKPRAEDSGEYHCVYHFVSAPKA-N 229
S WTK+ + + E RI D G Y CV + +A +
Sbjct: 151 SGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARD 210
Query: 230 ATIEVKAAPDITGHKRSENKNEGQD--ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSG 287
+ V A P I G + +D + C++ G P P+ W K +P TS
Sbjct: 211 FQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLP-----TST 265
Query: 288 RFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
+ ++ +L + Q + D G Y C A+NA+G+A T L V
Sbjct: 266 K--VVYTRGGRQLQLGRAQ-SSDAGVYTCKASNAVGAAEKATRLDV 308
Score = 50.1 bits (118), Expect = 4e-06
Identities = 74/320 (23%), Positives = 120/320 (37%), Gaps = 58/320 (18%)
Query: 15 LLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAES 74
+LV + P Q+A V+ GD L C+ P P + W+
Sbjct: 1743 VLVPPAFRQAPRGPQDAVLVR--------VGDKAVLSCETDALPEPTVTWYK-------- 1786
Query: 75 FRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSIT 134
DG + V G L I + D G Y C+ SN
Sbjct: 1787 -----DG--QPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSN-------------- 1825
Query: 135 WIRAQA----TISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNG- 188
+ +A T++V P + + P+ L C+++ + T+T W K+
Sbjct: 1826 -VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVT---WLKDRM 1881
Query: 189 -VELSATRKNASNM-EYRINKPRAEDSGEYHCVYHFVSAP-KANATIEVKAAPDI--TGH 243
VE SA S ++++ + +G Y CV A + + + V AP I +G
Sbjct: 1882 PVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGV 1941
Query: 244 KRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIV 303
R + EGQ+ + C++ G P PD W K + + D + RF++ + L +
Sbjct: 1942 AREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQD-MGPHLRFYL----DGGSLVLK 1996
Query: 304 NLQITEDPGEYECNATNAIG 323
L+ D G Y C A N G
Sbjct: 1997 GLR-ASDAGAYTCVAHNPAG 2015
Score = 50.1 bits (118), Expect = 4e-06
Identities = 71/302 (23%), Positives = 114/302 (37%), Gaps = 56/302 (18%)
Query: 45 GDAFELYCDVVGSPTPEIQWWY-AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRI 103
G EL C+ G P P + W E ++S Q G S L++
Sbjct: 2139 GSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQ-------------------GPS-LQL 2178
Query: 104 TRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS-EEVIIRDSP 162
+ DSGTY C A ++ R ++V++ P I S + + +P
Sbjct: 2179 EAVGAGDSGTYSCVAVSEAGE-----------ARRHFQLTVMEPPHIEDSGQPTELSLTP 2227
Query: 163 VLPVTLQCNLTSSSH-TLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCVYH 221
P+ L C+ + +T W K+G L+ N+ R D+G Y C+
Sbjct: 2228 GAPMELLCDAQGTPQPNIT---WHKDGQALTRLENNSRATRVL----RVRDAGLYTCLAE 2280
Query: 222 F-VSAPKANATIEVKAAPDITGHKRSE---NKNEGQDATMYCKSVGYPHPDWIWRKKENG 277
A + + + V+A P+I G + GQ + C P P W + +G
Sbjct: 2281 SPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQ-LVLECSVEAEPAPKITWHR--DG 2337
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHL 337
+ ++ + + +L ++ T D G+Y C A NA GS SV RV H
Sbjct: 2338 I---VLQEDAHTQFPERGRFLQLQALS---TADSGDYSCTARNAAGSTSV--AFRVEIHT 2389
Query: 338 AP 339
P
Sbjct: 2390 VP 2391
Score = 47.4 bits (111), Expect = 2e-05
Identities = 69/312 (22%), Positives = 113/312 (36%), Gaps = 58/312 (18%)
Query: 36 SPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGS 95
SP + T L C+ GSP P + WW DG + AY
Sbjct: 2487 SPSNLTLTAHTPALLPCEASGSPKPLVVWWK-------------DGQKLDFRLQQGAYRL 2533
Query: 96 NGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEE 155
+ L +T +DS +EC SN+ Q T+ V P + ++
Sbjct: 2534 LPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLY---------QVTVHV---PPTIADDQ 2581
Query: 156 VIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAED-- 212
+ + PV L C+ T + T++ W+K G +L A YR++ A +
Sbjct: 2582 TDFTVTMMAPVVLTCHSTGIPAPTVS---WSKAGAQLGARGSG-----YRVSPSGALEIG 2633
Query: 213 ------SGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYP 265
+G Y C + + + V+A+P + ++ + C++ G P
Sbjct: 2634 QALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIP 2693
Query: 266 HPDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 322
P W+K+ + + V G+ I + ED G Y C A N+
Sbjct: 2694 RPTITWQKEGLNVATGVSTQVLPGGQLRIAHAS------------PEDAGNYLCIAKNSA 2741
Query: 323 GSASVVTVLRVR 334
GSA T L V+
Sbjct: 2742 GSAMGKTRLVVQ 2753
Score = 46.2 bits (108), Expect = 5e-05
Identities = 74/307 (24%), Positives = 114/307 (37%), Gaps = 46/307 (14%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
T + + L CDV P PE+ W+ + ++A S + + G
Sbjct: 1666 TAILNSSVSLPCDVHAHPNPEVTWY--KDSQALSLGE-------------EVFLLPGTHT 1710
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRD 160
L++ R L DSG Y C A N R+ + + + Q PR + V++R
Sbjct: 1711 LQLGRARLSDSGMYTCEALNAAGRDQ-----KLVQLSVLVPPAFRQAPR-GPQDAVLVRV 1764
Query: 161 SPVLPVTLQCNLTS-SSHTLTYSYWTKNGVEL---SATRKNASNMEYRINKPRAEDSGEY 216
L C + T+T W K+G L T+ I + + D G Y
Sbjct: 1765 GD--KAVLSCETDALPEPTVT---WYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLY 1819
Query: 217 HCVYHFVSAPKANA-TIEVKAAPDITGHK-RSENKNEGQDATMYCKSVGYPHPDWIWRKK 274
C V+ T+ V+ P K + ++ G + C G P P W K
Sbjct: 1820 SCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLK- 1878
Query: 275 ENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS---VVTVL 331
+ MP V +S ++++ L + LQ + G Y C A N A VV VL
Sbjct: 1879 -DRMP---VESSAVHGVVSRGG--RLQLSRLQPAQ-AGTYTCVAENTQAEARKDFVVAVL 1931
Query: 332 ---RVRS 335
R+RS
Sbjct: 1932 VAPRIRS 1938
Score = 45.4 bits (106), Expect = 9e-05
Identities = 74/324 (22%), Positives = 122/324 (37%), Gaps = 60/324 (18%)
Query: 14 LLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAE 73
LL+++ + G GAAQ L G EL C G PTP+++W +
Sbjct: 119 LLVLTPPSVLGAGAAQEV---------LGLAGADVELQCWTSGVPTPQVEW-------TK 162
Query: 74 SFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSI 133
+ + G +V VLRIT + D G Y+C A + P R
Sbjct: 163 DRQPVLPGGPHLQV-------QEDGQVLRITGSHVGDEGRYQCVAFS-PAGQQARD---- 210
Query: 134 TWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSA 193
+R A ++ T E ++ D V + + + + T W K+G L
Sbjct: 211 FQLRVHAPPTIWGSNE--TGEVAVMEDHLVQLLCEARGVPTPNIT-----WFKDGALLPT 263
Query: 194 TRK---NASNMEYRINKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDIT---GHKRS 246
+ K + ++ + ++ D+G Y C + V A + ++V P I G
Sbjct: 264 STKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYV 323
Query: 247 ENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQ 306
G+ + C + G+P P W G+P+ N S T+ +++ L
Sbjct: 324 VKAVAGRPVALECVARGHPSPTLSWH--HEGLPVAESNES--------RLETDGSVLRL- 372
Query: 307 ITEDPGE-----YECNATNAIGSA 325
E PGE Y C A++ G A
Sbjct: 373 --ESPGEASSGLYSCVASSPAGEA 394
Score = 44.7 bits (104), Expect = 1e-04
Identities = 65/312 (20%), Positives = 106/312 (33%), Gaps = 60/312 (19%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
L L C+ G+P+P + W L DG G VL
Sbjct: 708 LVNTPVRLTCNATGAPSPTLMW-------------LKDGNPVSPAGTPGLQVFPGGRVLT 754
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSE---EVIIR 159
+ DSG Y C A + ++ R + V P I+ E V+
Sbjct: 755 LASARASDSGRYSCVAVS-----------AVGEDRQDVVLQVHMPPSILGEELNVSVVAN 803
Query: 160 DSPVLPVTLQCNLTSSSHTLTYSY--WTKNGVELS---ATRKNASNMEYRINKPRAEDSG 214
+S V L+C SH + W K+G L +A ++++ D+G
Sbjct: 804 ES----VALECQ----SHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAG 855
Query: 215 EYHC-VYHFVSAPKANATIEVKAAPDIT-GHKRSENKNEGQDATMYCKSVGYPHPDWIWR 272
Y C + + + + V AP + EG + C+ G P P WR
Sbjct: 856 HYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWR 915
Query: 273 KKENGMP-----MDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASV 327
K +P + V+ GR + + + G Y C +N +G++S
Sbjct: 916 KDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQ-----------EGTYTCECSNVVGNSS- 963
Query: 328 VTVLRVRSHLAP 339
L++ H+ P
Sbjct: 964 -QDLQLEVHVPP 974
Score = 41.2 bits (95), Expect = 0.002
Identities = 57/251 (22%), Positives = 91/251 (36%), Gaps = 41/251 (16%)
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS--EEVII 158
L+I ++ L D G Y C A+N + + + + VL P I + ++
Sbjct: 568 LQIEKVDLRDEGIYTCAATNLAGES-----------KREVALKVLVPPNIEPGPVNKAVL 616
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSA---TRKNASNMEYRINKPRAEDSGE 215
++ VTL+C L S S W K +S+ + RI + + D+G
Sbjct: 617 ENA---SVTLEC-LASGVPPPDVS-WFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGS 671
Query: 216 YHCVYHFVSAP-------KANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPD 268
Y CV V+ + N + P + G + C + G P P
Sbjct: 672 YRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNT-----PVRLTCNATGAPSPT 726
Query: 269 WIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVV 328
+W K +G P+ T G T + D G Y C A +A+G
Sbjct: 727 LMWLK--DGNPVSPAGTPGLQVFPGGRVLT----LASARASDSGRYSCVAVSAVGEDRQD 780
Query: 329 TVLRVRSHLAP 339
VL+V H+ P
Sbjct: 781 VVLQV--HMPP 789
Score = 40.8 bits (94), Expect = 0.002
Identities = 65/319 (20%), Positives = 112/319 (35%), Gaps = 78/319 (24%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGAR-KRRVTVNTAYGSNGVS 99
T + L C+ + P+P I W + DGA + + G++G+
Sbjct: 1270 TVTVNNPISLICEALAFPSPNITW-------------MKDGAPFEASRNIQLLPGTHGLQ 1316
Query: 100 VLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIR 159
+L + ED+G Y C +N+ + + VL P I +
Sbjct: 1317 ILNAQK---EDAGQYTCVVTNELGEAVKNYH-----------VEVLIPPSIS-------K 1355
Query: 160 DSPVLPVTLQCNLTSSSHTLTYSY-----------WTKNGVELSATRKNASNMEYR---I 205
D P+ V ++ T + TLT W K+G ++ + + E R I
Sbjct: 1356 DDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQI 1415
Query: 206 NKPRAEDSGEYHCVYHFVSAPKA---NATIEV----------KAAPDITGHKRSENKN-- 250
+ DSG Y CV V+ N I+V AA +I +
Sbjct: 1416 QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVT 1475
Query: 251 ------EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVN 304
E A +YC + P PD W +++ + + ++ ++ +V
Sbjct: 1476 EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPL-----SAGDEVSVLQGGRVLQIPLVR 1530
Query: 305 LQITEDPGEYECNATNAIG 323
E+ G Y C A+N +G
Sbjct: 1531 ---AENAGRYSCKASNEVG 1546
Score = 40.0 bits (92), Expect = 0.004
Identities = 52/232 (22%), Positives = 84/232 (36%), Gaps = 31/232 (13%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G+ + C V GSP + W L DG +GS LRI+
Sbjct: 2046 GELVTMVCPVRGSPPIHVSW-------------LKDGLPLPLSQRTLLHGSG--HTLRIS 2090
Query: 105 RLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVL 164
++ L D+G + C A++ D Q + + +P ++ V++R S
Sbjct: 2091 KVQLADAGIFTCVAASPAGVADRN-------FTLQVQVPPVLEPVEFQNDVVVVRGS--- 2140
Query: 165 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHCV-YHFV 223
V L C + L W K+G L ++ ++ A DSG Y CV
Sbjct: 2141 LVELPCE--ARGVPLPLVSWMKDGEPL-LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEA 2197
Query: 224 SAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRK 273
+ + + V P I +G + G + C + G P P+ W K
Sbjct: 2198 GEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHK 2249
Score = 39.3 bits (90), Expect = 0.006
Identities = 62/292 (21%), Positives = 104/292 (35%), Gaps = 45/292 (15%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
+ ++ L C P P + WW + R L + R V+ S ++L+
Sbjct: 801 VANESVALECQSHAMPPPVLSWW-------KDGRPL-----EPRPGVHL---SADKALLQ 845
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
+ R + D+G Y C A N ++ N ++ W+ A + L++ +T E
Sbjct: 846 VDRADVWDAGHYTCEALNQAGHSEKHYNLNV-WV---APVFPLRESHTLTVREGH----- 896
Query: 163 VLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME-----YRINKPRAEDSGEYH 217
P L C W K+G L ++ + + + G Y
Sbjct: 897 --PTRLSCECRGVPFPKIS--WRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYT 952
Query: 218 C-VYHFVSAPKANATIEVKAAPDITGHKRSENK-NEGQD--ATMYCKSVGYPHPDWIWRK 273
C + V + +EV P I G + + + QD AT+ C + G P P W +
Sbjct: 953 CECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWER 1012
Query: 274 KENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
+G P+ G + +N + V G Y C A N G A
Sbjct: 1013 --DGQPV------GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRA 1056
Score = 37.0 bits (84), Expect = 0.031
Identities = 71/307 (23%), Positives = 113/307 (36%), Gaps = 53/307 (17%)
Query: 50 LYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLT 107
L C+ P P I+W+ V + + L +G +L+I
Sbjct: 1377 LECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGR-----------------LLQIQPTQ 1419
Query: 108 LEDSGTYECRASN-----DPKRNDLRQNPSITWIRAQ--ATISVLQKPRI----VTSEEV 156
+ DSG Y C A+N D N L Q P + A +L + VT
Sbjct: 1420 VSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYRE 1479
Query: 157 IIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNA---SNMEYRINKPRAED 212
I+ ++P L C+ + LT W + LSA + + +I RAE+
Sbjct: 1480 IVENNPAY---LYCDTNAIPPPDLT---WYREDQPLSAGDEVSVLQGGRVLQIPLVRAEN 1533
Query: 213 SGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRS----ENKNEGQDATMYCKSVGYPHP 267
+G Y C + V + + V P I G N ++ C ++G P P
Sbjct: 1534 AGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVP 1593
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASV 327
W +NG+P + S R ++ +++ + D Y C A N GSA
Sbjct: 1594 TISWL--QNGLPF---SPSPRLQVLEDGQVLQVSTAEVA---DAASYMCVAENQAGSAEK 1645
Query: 328 VTVLRVR 334
+ LRV+
Sbjct: 1646 LFTLRVQ 1652
Score = 36.6 bits (83), Expect = 0.040
Identities = 23/81 (28%), Positives = 31/81 (38%), Gaps = 15/81 (18%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
T + G EL C GSP P IQW R S G +
Sbjct: 418 TTIVGQPLELPCQASGSPVPTIQW--------------LQNGRPAEELAGVQVASQG-TT 462
Query: 101 LRITRLTLEDSGTYECRASND 121
L I + L+ SG + C+A+N+
Sbjct: 463 LHIDHVELDHSGLFACQATNE 483
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 70.1 bits (170), Expect = 3e-12
Identities = 80/297 (26%), Positives = 125/297 (42%), Gaps = 50/297 (16%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGV---SVLRITRL 106
L C+ G+P+P I W +K + VNT+ ++ V L+I+R
Sbjct: 4007 LPCEATGTPSPFITW------------------QKEGINVNTSGRNHAVLPSGGLQISRA 4048
Query: 107 TLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPV 166
ED+GTY C A N ++ I+ + + P + E VI D P+
Sbjct: 4049 VREDAGTYMCVAQNP-------AGTALGKIKLNVQVPPVISPHL--KEYVIAVDK---PI 4096
Query: 167 TLQCNLTS-SSHTLTYSYWTKNG--VELSATRKNASNMEYRINKPRAEDSGEYHCVYHFV 223
TL C +T W K+G + S ++ S+ +I + D+G Y C+ V
Sbjct: 4097 TLSCEADGLPPPDIT---WHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANV 4153
Query: 224 SAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDI 282
+ + +T + V P I + NE A + C + G P P W KK+N + +
Sbjct: 4154 AGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINW-KKDNVL---L 4209
Query: 283 VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHLAP 339
N G++ E Y EL + N+ + ED G Y C A NA G + L V H+ P
Sbjct: 4210 ANLLGKY---TAEPYGELILENV-VLEDSGFYTCVANNAAGEDTHTVSLTV--HVLP 4260
Score = 69.3 bits (168), Expect = 6e-12
Identities = 83/307 (27%), Positives = 119/307 (38%), Gaps = 55/307 (17%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWW-------YAEVNRAESFRQLWDGARKR 85
F++ P + G L C V G P P I+W ++ S QL GA
Sbjct: 795 FIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA--- 851
Query: 86 RVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISV- 144
L I L D GTY C A N + I+++ T++V
Sbjct: 852 ---------------LFILNLWASDKGTYICEAENQFGK-----------IQSETTVTVT 885
Query: 145 -LQKPRIVTSEEV--IIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNA--S 199
L P I S V +I + TL C L + + + W KN L S
Sbjct: 886 GLVAPLIGISPSVANVIEGQQL---TLPCTLLAGN-PIPERRWIKNSAMLLQNPYITVRS 941
Query: 200 NMEYRINKPRAEDSGEYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMY 258
+ I + + +D GEY CV V+ T + V P I ++ + EG T+
Sbjct: 942 DGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLP 1001
Query: 259 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 318
CK+ G P P IW KK ++++TS F + L +V+ E+ GEY C A
Sbjct: 1002 CKASGNPKPSVIWSKKG-----ELISTSSAKFSAGADG--SLYVVS-PGGEESGEYVCTA 1053
Query: 319 TNAIGSA 325
TN G A
Sbjct: 1054 TNTAGYA 1060
Score = 65.9 bits (159), Expect = 6e-11
Identities = 74/307 (24%), Positives = 119/307 (38%), Gaps = 46/307 (14%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKR-RVTVNTAYGS 95
P + L G+ EL C+ G PTP IQW + + + G +R RV+ N
Sbjct: 3253 PSDVSVLLGENVELVCNANGIPTPLIQW-------LKDGKPIASGETERIRVSANG---- 3301
Query: 96 NGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEE 155
S L I D+G Y C A+N D N ++V P I +++
Sbjct: 3302 ---STLNIYGALTSDTGKYTCVATNPAGEEDRIFN-----------LNVYVTPTIRGNKD 3347
Query: 156 VIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVEL---SATRKNASNMEYRINKPRAED 212
+ ++ ++ ++ W KNG+ L S R A+ RI + + D
Sbjct: 3348 EAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSD 3407
Query: 213 SGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKN--EGQDATMYCKSVGYPHPDW 269
Y CV + + ++V A P++ +E +G +M C + G P P
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSM 3467
Query: 270 IWRKKENGMPMD---IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
W + + +D V+T G + K TED G+Y C A+N G S
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE-----------TEDSGKYTCIASNEAGEVS 3516
Query: 327 VVTVLRV 333
+L+V
Sbjct: 3517 KHFILKV 3523
Score = 64.3 bits (155), Expect = 2e-10
Identities = 77/314 (24%), Positives = 122/314 (38%), Gaps = 56/314 (17%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F + P + G+ L C G P P++ W + F +
Sbjct: 4262 FTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSV-------------- 4307
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
NG S L I R++ EDSGTY C A N S+ +++A + V + P
Sbjct: 4308 ---NGHSELVIERVSKEDSGTYVCTAEN-----------SVGFVKAIGFVYVKEPP---- 4349
Query: 153 SEEVIIRDSP---VLPV----TLQCNLTSSSHTLTYSYWTKNGV--ELSATRKNASNMEY 203
V D P + P+ L C + T T W + GV E+S + N
Sbjct: 4350 ---VFKGDYPSNWIEPLGGNAILNCEV-KGDPTPTIQ-WNRKGVDIEISHRIRQLGNGSL 4404
Query: 204 RINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSV 262
I ED+G+Y CV + + + ++ +++ P IT N G + C++
Sbjct: 4405 AIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQAT 4464
Query: 263 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 322
G P P W ++ + + D +N + L I + Q ED E+EC A N +
Sbjct: 4465 GEPQPTITWSRQGHSISWD--------DRVNVLSNNSLYIADAQ-KEDTSEFECVARNLM 4515
Query: 323 GSASVVTVLRVRSH 336
GS V + V+ H
Sbjct: 4516 GSVLVRVPVIVQVH 4529
Score = 63.5 bits (153), Expect = 3e-10
Identities = 73/319 (22%), Positives = 121/319 (37%), Gaps = 38/319 (11%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
P +++ G + C G P P+I W ++ S R Y
Sbjct: 618 PKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHR----------------YRMT 661
Query: 97 GVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEV 156
L I +D+G Y C ASN + +QN ++ +I A + V+Q +V ++
Sbjct: 662 SDGTLFIKNAAPKDAGIYGCLASNSAGTD--KQNSTLRYIEAPK-LMVVQSELLVALGDI 718
Query: 157 IIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEY---RINKPRAEDS 213
+ ++C +S W K +EL + + +I + + D+
Sbjct: 719 TV---------MECK--TSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDA 767
Query: 214 GEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 272
G+Y CV + T++V + P + G + T+ C GYP P WR
Sbjct: 768 GDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWR 827
Query: 273 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 332
+ +N M I + I++ L I+NL D G Y C A N G T +
Sbjct: 828 RLDN---MPIFSRPFSVSSISQLRTGALFILNLW-ASDKGTYICEAENQFGKIQSETTVT 883
Query: 333 VRSHLAPLWPFLGILAEII 351
V +APL +A +I
Sbjct: 884 VTGLVAPLIGISPSVANVI 902
Score = 62.8 bits (151), Expect = 5e-10
Identities = 70/283 (24%), Positives = 117/283 (41%), Gaps = 42/283 (14%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE 109
L C+ G P P + W L DG+ + N +G +L +T +
Sbjct: 2031 LECEARGIPAPSLTW-------------LKDGSPVSSFS-NGLQVLSGGRILALTSAQIS 2076
Query: 110 DSGTYECRASN---DPKRN-DLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLP 165
D+G Y C A N + +R+ DLR + + +SVL I + E++ + + P
Sbjct: 2077 DTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL----ISQAVELLCQSDAIPP 2132
Query: 166 VTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHC-VYHFVS 224
TL H L K G+ +S R +I + +D+G Y C +
Sbjct: 2133 PTL--TWLKDGHPLL----KKPGLSISENRS-----VLKIEDAQVQDTGRYTCEATNVAG 2181
Query: 225 APKANATIEVKAAPDITGHKRSENKN--EGQDATMYCKSVGYPHPDWIWRKKENGMPMDI 282
+ N + + P+I G EG ++ C+S G P P+ IW+KK G P+ +
Sbjct: 2182 KTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKK--GSPV-L 2238
Query: 283 VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
++ GR I++ +++I D Y C A+N G+A
Sbjct: 2239 TDSMGRVRILSGGRQLQISIAE---KSDAALYSCVASNVAGTA 2278
Score = 62.8 bits (151), Expect = 5e-10
Identities = 73/286 (25%), Positives = 112/286 (39%), Gaps = 39/286 (13%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
+ + EL C G P P++ W + DG + G G VLR
Sbjct: 3541 IVNNPLELTCIASGIPAPKMTW-------------MKDGRPLPQTDQVQTLG--GGEVLR 3585
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
I+ +ED+G Y C AS+ +D + + I+ +PR +T ++R+
Sbjct: 3586 ISTAQVEDTGRYTCLASSPAGDDD---KEYLVRVHVPPNIAGTDEPRDIT----VLRNR- 3637
Query: 163 VLPVTLQCNLTSSSHTLTYSYWTKNGVELSAT---RKNASNMEYRINKPRAEDSGEYHCV 219
VTL+C S + W +NG L AT R + +IN D+ Y CV
Sbjct: 3638 --QVTLECK--SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCV 3693
Query: 220 YHFVSAPKANATI-EVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 278
++ I V P+I G +S + + C + G P P WRK
Sbjct: 3694 ASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKD---- 3749
Query: 279 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 324
+ R+ I+ L+I + +T D G Y C ATNA G+
Sbjct: 3750 GAVLAGNHARYSILEN---GFLHIQSAHVT-DTGRYLCMATNAAGT 3791
Score = 62.0 bits (149), Expect = 9e-10
Identities = 71/289 (24%), Positives = 115/289 (39%), Gaps = 54/289 (18%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE 109
L+C+V G+P+P I W+ V ES T+ T N +L++ R T E
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESS------------TIQTV---NNGKILKLFRATPE 1424
Query: 110 DSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS------EEVIIRDSPV 163
D+G Y C+A N + N I VL P I+ + V+ RD
Sbjct: 1425 DAGRYSCKAINIAGTSQKYFN-----------IDVLVPPTIIGTNFPNEVSVVLNRD--- 1470
Query: 164 LPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME----YRINKPRAEDSGEYHCV 219
V L+C + + +W K+G L N ++ + R D G Y C
Sbjct: 1471 --VALECQVKGT--PFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCT 1526
Query: 220 YHFVSAPKA-NATIEVKAAPDITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKEN 276
+ +A + + + P I G + + + + C++ G P P W K +
Sbjct: 1527 VSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYK--D 1584
Query: 277 GMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
G P + +S + I+K Y L+I Q++ D Y C+ N G+A
Sbjct: 1585 GQP---IMSSSQALYIDKGQY--LHIPRAQVS-DSATYTCHVANVAGTA 1627
Score = 62.0 bits (149), Expect = 9e-10
Identities = 75/318 (23%), Positives = 129/318 (40%), Gaps = 52/318 (16%)
Query: 35 KSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYG 94
+SP + + + ++ L C+ G P P I W F+ W + V +
Sbjct: 2391 RSPENISVVEKNSVSLTCEASGIPLPSITW----------FKDGWPVSLSNSVRI----- 2435
Query: 95 SNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV--- 151
+G +LR+ + T+ED+G Y C N R +SVL P IV
Sbjct: 2436 LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEE-----------RKIFGLSVLVPPHIVGEN 2484
Query: 152 TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKN---ASNMEYRINKP 208
T E+V +++ VTL C +T + + W K+G L + + +I
Sbjct: 2485 TLEDVKVKEKQ--SVTLTCEVT--GNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNV 2540
Query: 209 RAEDSGEYHCVYHFVSAPKANA-TIEVKAAPDITGHKRSENKNE-----GQDATMYCKSV 262
+ +G Y C+ + K+ + ++ V +P I G N + ++ C++
Sbjct: 2541 QVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAY 2600
Query: 263 GYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAI 322
YP W K +G P++ S R I T L I+N Q ++ G Y C ATN
Sbjct: 2601 SYPPATITWFK--DGTPLE----SNRNIRILPGGRT-LQILNAQ-EDNAGRYSCVATNEA 2652
Query: 323 GSASVVTVLRVRSHLAPL 340
G ++ V+ ++ P+
Sbjct: 2653 G--EMIKHYEVKVYIPPI 2668
Score = 61.6 bits (148), Expect = 1e-09
Identities = 57/242 (23%), Positives = 97/242 (40%), Gaps = 38/242 (15%)
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRD 160
L I ++TL D G YEC A + RAQ V + P ++ +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTG-----------RAQTFFDVSEPPPVIQVPNNVTV- 531
Query: 161 SPVLPVTLQCNLTSS-SHTLTYSYWTKNGVELS----ATRKNASNMEYRINKPRAEDSGE 215
+P L C + S+ + LT W +N ++ A + +N+ + + D+GE
Sbjct: 532 TPGERAVLTCLIISAVDYNLT---WQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGE 588
Query: 216 YHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKK 274
YHC+ A + + V+ P +T ++++ G + ++ C + GYP P W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAW--- 645
Query: 275 ENGMPMDIVNTSGRFFIINKENYTELNIVNLQI----TEDPGEYECNATNAIGSASVVTV 330
T FI+ Y + L I +D G Y C A+N+ G+ +
Sbjct: 646 ----------TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695
Query: 331 LR 332
LR
Sbjct: 696 LR 697
Score = 60.8 bits (146), Expect = 2e-09
Identities = 76/340 (22%), Positives = 137/340 (40%), Gaps = 56/340 (16%)
Query: 25 PGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARK 84
P + ++AG + ++ET L + +L C G+P P I W+ +L G+
Sbjct: 1918 PPSLEDAGKM---LNETVLVSNPVQLECKAAGNPVPVITWY--------KDNRLLSGSTS 1966
Query: 85 RRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISV 144
N ++ I + D+G Y+C A N +L + ++ S+
Sbjct: 1967 MTFL-------NRGQIIDIESAQISDAGIYKCVAINSAGATELFYS-----LQVHVAPSI 2014
Query: 145 LQKPRIVTSEEVIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNME- 202
+V V++ + PV L+C + +LT W K+G +S+ +
Sbjct: 2015 SGSNNMVA---VVVNN----PVRLECEARGIPAPSLT---WLKDGSPVSSFSNGLQVLSG 2064
Query: 203 ---YRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMY 258
+ + D+G Y CV + + + + V P+I G +++ + Q +
Sbjct: 2065 GRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELL 2124
Query: 259 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 318
C+S P P W K +G P ++ G + EN + L I + Q+ +D G Y C A
Sbjct: 2125 CQSDAIPPPTLTWLK--DGHP--LLKKPG---LSISENRSVLKIEDAQV-QDTGRYTCEA 2176
Query: 319 TNAIGSASVVTVLRVRSHLAPLW--PFLGILAEIIILVVI 356
TN G +++ +W P +G E+ L VI
Sbjct: 2177 TNVAGKTE-------KNYNVNIWVPPNIGGSDELTQLTVI 2209
Score = 60.1 bits (144), Expect = 3e-09
Identities = 71/295 (24%), Positives = 118/295 (40%), Gaps = 54/295 (18%)
Query: 45 GDAFELYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
G + L C+V G P P + W + +A+ L +G +L+
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG-----------------HILQ 2349
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
+ + + D+G Y C A N D + + S+ A S++ R + V+ ++S
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV-----HAPPSIIGNHRSPENISVVEKNS- 2403
Query: 163 VLPVTLQCNLTSSSHTLTYSYWTKNGVELS---ATRKNASNMEYRINKPRAEDSGEYHCV 219
V+L C +S L W K+G +S + R + R+ + ED+G+Y CV
Sbjct: 2404 ---VSLTCE--ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCV 2458
Query: 220 YHFVSAPKANA-TIEVKAAPDITGHKRSEN--KNEGQDATMYCKSVGYPHPDWIWRKKEN 276
+ + + V P I G E+ E Q T+ C+ G P P+ W K +
Sbjct: 2459 VRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK--D 2516
Query: 277 GMPMD-----IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
G P+ + + GRF L I N+Q+ G Y C A++ G S
Sbjct: 2517 GQPLQEDEAHHIISGGRF----------LQITNVQVPH-TGRYTCLASSPAGHKS 2560
Score = 59.3 bits (142), Expect = 6e-09
Identities = 72/302 (23%), Positives = 109/302 (36%), Gaps = 57/302 (18%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
P + T + L C+ G P P I W RK +N N
Sbjct: 3810 PTNMTVIVNVQTTLACEATGIPKPSINW------------------RKNGHLLNVDQNQN 3851
Query: 97 GVSVLR-----ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV 151
+L I +++D+ TYEC +N D ++ +T +Q P +
Sbjct: 3852 SYRLLSSGSLVIISPSVDDTATYECTVTNG--AGDDKRTVDLT----------VQVPPSI 3899
Query: 152 TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVEL---SATRKNASNMEYRINKP 208
E + P + C T+S +WTKNG+ L + S+ I
Sbjct: 3900 ADEPTDFLVTKHAPAVITC--TASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILAT 3957
Query: 209 RAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHP 267
+ +G Y CV + + + T+ V P I + + C++ G P P
Sbjct: 3958 QLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSP 4017
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----EDPGEYECNATNAIG 323
W+K+ VNTSGR N+ L LQI+ ED G Y C A N G
Sbjct: 4018 FITWQKEGIN-----VNTSGR-------NHAVLPSGGLQISRAVREDAGTYMCVAQNPAG 4065
Query: 324 SA 325
+A
Sbjct: 4066 TA 4067
Score = 58.5 bits (140), Expect = 1e-08
Identities = 71/306 (23%), Positives = 124/306 (40%), Gaps = 49/306 (16%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
+ + EL C V GSP P I W ++ + F+ L +G +
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK----------------- 1789
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRD 160
L I + + ++G Y C A+N D ++ +T + TI SE V+++
Sbjct: 1790 LVIAQAQVSNTGLYRCMAAN--TAGDHKKEFEVT-VHVPPTIK-----SSGLSERVVVKY 1841
Query: 161 SPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKN----ASNMEYRINKPRAEDSGEY 216
PV + + + S T W K+ ++ + N +S +I K ED+G Y
Sbjct: 1842 KPVALQCIANGIPNPSIT-----WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 217 HCV-YHFVSAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRK 273
CV + + + + V P + G +E + CK+ G P P W K
Sbjct: 1897 TCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYK 1956
Query: 274 KENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
+++ S +N+ ++I + QI+ D G Y+C A N+ G+ + L+V
Sbjct: 1957 DNR-----LLSGSTSMTFLNRGQI--IDIESAQIS-DAGIYKCVAINSAGATELFYSLQV 2008
Query: 334 RSHLAP 339
H+AP
Sbjct: 2009 --HVAP 2012
Score = 58.5 bits (140), Expect = 1e-08
Identities = 72/303 (23%), Positives = 116/303 (38%), Gaps = 54/303 (17%)
Query: 45 GDAFELYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
G + L C+ P P I W+ + + L DG +L
Sbjct: 3074 GTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG-----------------QMLH 3116
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
I + + D+G Y CRA N R+D + ++V P I E +I ++
Sbjct: 3117 IKKAEVSDTGQYVCRAINVAGRDDKNFH-----------LNVYVPPSIEGPEREVIVETI 3165
Query: 163 VLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYR---------INKPRAEDS 213
PVTL C+ T W KN + +N+ ++E R I + + DS
Sbjct: 3166 SNPVTLTCDATGIPPPTI--AWLKNHKRI----ENSDSLEVRILSGGSKLQIARSQHSDS 3219
Query: 214 GEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNE--GQDATMYCKSVGYPHPDWI 270
G Y C+ + + + ++ P + G + + + G++ + C + G P P
Sbjct: 3220 GNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 271 WRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTV 330
W K +G P+ T I N + LNI +T D G+Y C ATN G +
Sbjct: 3280 WLK--DGKPIASGETER---IRVSANGSTLNIYG-ALTSDTGKYTCVATNPAGEEDRIFN 3333
Query: 331 LRV 333
L V
Sbjct: 3334 LNV 3336
Score = 57.4 bits (137), Expect = 2e-08
Identities = 77/318 (24%), Positives = 123/318 (38%), Gaps = 55/318 (17%)
Query: 36 SPMSETKLTGDAFELYCDVV-GSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYG 94
SP + G L C ++ G+P PE +W + + Q +TV + G
Sbjct: 895 SPSVANVIEGQQLTLPCTLLAGNPIPERRW----IKNSAMLLQ------NPYITVRSD-G 943
Query: 95 SNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSE 154
S L I R+ L+D G Y C ASN N+ + T V+ +
Sbjct: 944 S-----LHIERVQLQDGGEYTCVASNVAGTNN------------KTTSVVVHVLPTIQHG 986
Query: 155 EVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNAS---NMEYRINKPRAE 211
+ I+ +PVTL C +S + W+K G +S + S + + P E
Sbjct: 987 QQILSTIEGIPVTLPCK--ASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGE 1044
Query: 212 DSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNE--------GQDATMYCKSV 262
+SGEY C + K + V P + G +R ++++ G++ T+ C+
Sbjct: 1045 ESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVK 1104
Query: 263 GYPHPDWIWRKKENGM-PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNA 321
P P W K+ + P +T F TE T D G Y C ATN
Sbjct: 1105 SLPPPIITWAKETQLISPFSPRHT---FLPSGSMKITETR------TSDSGMYLCVATNI 1155
Query: 322 IGSASVVTVLRVRSHLAP 339
G +V +++ H+ P
Sbjct: 1156 AG--NVTQAVKLNVHVPP 1171
Score = 55.1 bits (131), Expect = 1e-07
Identities = 72/295 (24%), Positives = 112/295 (37%), Gaps = 52/295 (17%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
+ + LYC+ +P P + W+ S + L G VL+
Sbjct: 2790 IINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLI---------------LPGGRVLQ 2834
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
I R +ED+G Y C A N+ + L Q + VL P I + + +
Sbjct: 2835 IPRAKVEDAGRYTCVAVNEAGEDSL-----------QYDVRVLVPPIIKGANSDLPEEVT 2883
Query: 163 VL---PVTLQCNLTSSSHTLTYSYWTKNGVEL--SATRKNASNME-YRINKPRAEDSGEY 216
VL ++C SS + W K+G L K SN +I + D G Y
Sbjct: 2884 VLVNKSALIEC--LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRY 2941
Query: 217 HCV-YHFVSAPKANATIEVKAAPDITGHKRSENKN--EGQDATMYCKSVGYPHPDWIWRK 273
CV + + K + V P + G K SEN ++ C+ G+P PD W K
Sbjct: 2942 VCVAENTAGSAKKYFNLNVHVPPSVIGPK-SENLTVVVNNFISLTCEVSGFPPPDLSWLK 3000
Query: 274 KENGMPMD---IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
E + ++ ++ GR L I+ +++ D GEY C A N G +
Sbjct: 3001 NEQPIKLNTNTLIVPGGR----------TLQIIRAKVS-DGGEYTCIAINQAGES 3044
Score = 54.3 bits (129), Expect = 2e-07
Identities = 64/301 (21%), Positives = 108/301 (35%), Gaps = 43/301 (14%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
+ G L C G+P P + +W + T + + + L
Sbjct: 993 IEGIPVTLPCKASGNPKPSV---------------IWSKKGELISTSSAKFSAGADGSLY 1037
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
+ E+SG Y C A+N + + + + ++V +PR+ + + +D P
Sbjct: 1038 VVSPGGEESGEYVCTATN-----------TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKP 1086
Query: 163 VL-------PVTLQCNLTS-SSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSG 214
V VTL C + S +T++ T+ S + +I + R DSG
Sbjct: 1087 VEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSG 1146
Query: 215 EYHCVYHFVSAPKANAT-IEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRK 273
Y CV ++ A + V P I + GQ + C + G P P W K
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSK 1206
Query: 274 KENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
+ M +D G + N + ++ D G Y C ATN G+ L V
Sbjct: 1207 GGSTMLVD-----GEHHVSNPDGTLSIDQAT---PSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 334 R 334
+
Sbjct: 1259 Q 1259
Score = 54.3 bits (129), Expect = 2e-07
Identities = 73/315 (23%), Positives = 113/315 (35%), Gaps = 52/315 (16%)
Query: 34 VKSPMSE--TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNT 91
V P SE T + + L C+V G P P++ W E + ++ NT
Sbjct: 2966 VIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNE--------------QPIKLNTNT 3011
Query: 92 AYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV 151
G L+I R + D G Y C A N + + + +++V P I
Sbjct: 3012 LIVPGG-RTLQIIRAKVSDGGEYTCIAINQAGES-----------KKKFSLTVYVPPSIK 3059
Query: 152 TSEE---VIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNG---VELSATRKNASNMEYRI 205
+ ++ V+L+C S++ W KNG E + A I
Sbjct: 3060 DHDSESLSVVNVREGTSVSLECE--SNAVPPPVITWYKNGRMITESTHVEILADGQMLHI 3117
Query: 206 NKPRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSE-NKNEGQDATMYCKSVG 263
K D+G+Y C + N + V P I G +R + T+ C + G
Sbjct: 3118 KKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATG 3177
Query: 264 YPHPDWIWRKK----ENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNAT 319
P P W K EN +++ SG ++L I Q D G Y C A+
Sbjct: 3178 IPPPTIAWLKNHKRIENSDSLEVRILSGG---------SKLQIARSQ-HSDSGNYTCIAS 3227
Query: 320 NAIGSASVVTVLRVR 334
N G A L ++
Sbjct: 3228 NMEGKAQKYYFLSIQ 3242
Score = 52.8 bits (125), Expect = 5e-07
Identities = 67/292 (22%), Positives = 109/292 (37%), Gaps = 50/292 (17%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE 109
L C+ G P P+I W ES RQ RV + + L+I +
Sbjct: 4098 LSCEADGLPPPDITWHKDGRAIVESIRQ--------RVLSSGS--------LQIAFVQPG 4141
Query: 110 DSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSE---EVIIRDSPVLPV 166
D+G Y C A+N + ++V PRI ++E V +LP
Sbjct: 4142 DAGHYTCMAANVAGSSS-----------TSTKLTVHVPPRIRSTEGHYTVNENSQAILPC 4190
Query: 167 TLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYR---INKPRAEDSGEYHCVYHFV 223
T + + W K+ V L+ + Y + EDSG Y CV +
Sbjct: 4191 VADGIPTPAIN------WKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNA 4244
Query: 224 SAPKANA-TIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDI 282
+ + ++ V P T + N+G+ + CK+ G P P W N +P
Sbjct: 4245 AGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHF 4304
Query: 283 VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
+ +G ++EL ++ ED G Y C A N++G + + V+
Sbjct: 4305 DSVNG---------HSEL-VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346
Score = 52.0 bits (123), Expect = 9e-07
Identities = 75/367 (20%), Positives = 143/367 (38%), Gaps = 63/367 (17%)
Query: 40 ETKLTGDAFELYCDVVGSPTPEIQWWY---AEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
+ ++ E C G+P P I+W + R L DG
Sbjct: 1276 QERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG--------------- 1320
Query: 97 GVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEV 156
++L I +T D+G Y C A N+ + + N + P ++ +E
Sbjct: 1321 --TLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKV------------HVPPVIKDKEQ 1366
Query: 157 IIRDSPVLP--VTLQCNLTSSSHTLTYSYWTKNGVEL--SATRKNASNME-YRINKPRAE 211
+ S +L L C + + + W K+ V++ S+T + +N + ++ + E
Sbjct: 1367 VTNVSVLLNQLTNLFCEVEGTPSPII--MWYKDNVQVTESSTIQTVNNGKILKLFRATPE 1424
Query: 212 DSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNE-----GQDATMYCKSVGYP 265
D+G Y C + + I+V P I G + NE +D + C+ G P
Sbjct: 1425 DAGRYSCKAINIAGTSQKYFNIDVLVPPTIIG---TNFPNEVSVVLNRDVALECQVKGTP 1481
Query: 266 HPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
PD W K +G P+ + + + + L++ N + D G Y+C +NA G
Sbjct: 1482 FPDIHWFK--DGKPLFLGDPNVELL----DRGQVLHLKNAR-RNDKGRYQCTVSNAAGKQ 1534
Query: 326 SVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEVP------DAGPMKTNS 379
+ +++ ++ P + +I +L+ ++ E R +P D P+ ++S
Sbjct: 1535 A--KDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS 1592
Query: 380 TNNHKDK 386
+ DK
Sbjct: 1593 QALYIDK 1599
Score = 48.5 bits (114), Expect = 1e-05
Identities = 71/302 (23%), Positives = 115/302 (38%), Gaps = 43/302 (14%)
Query: 41 TKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
T + G+ L C+ G P P + W + + L D + R+ +G
Sbjct: 2207 TVIEGNLISLLCESSGIPPPNLIW------KKKGSPVLTDSMGRVRIL-------SGGRQ 2253
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRD 160
L+I+ D+ Y C ASN N + +IR T S I+ +
Sbjct: 2254 LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV-YIRPTITNSGSHPTEIIVTRG----- 2307
Query: 161 SPVLPVTLQCNLTS-SSHTLTYSYWTKNG---VELSATRKNASNMEYRINKPRAEDSGEY 216
++L+C + T+T W K+G ++ ++ D+G Y
Sbjct: 2308 ---KSISLECEVQGIPPPTVT---WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 217 HCV-YHFVSAPKANATIEVKAAPDITGHKRS-ENKN--EGQDATMYCKSVGYPHPDWIWR 272
CV + + V A P I G+ RS EN + E ++ C++ G P P W
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWF 2421
Query: 273 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT-EDPGEYECNATNAIGSASVVTVL 331
K +G P+ + N+ I++ L +Q T ED G+Y C NA G + L
Sbjct: 2422 K--DGWPVSLSNS---VRILSGGRMLRL----MQTTMEDAGQYTCVVRNAAGEERKIFGL 2472
Query: 332 RV 333
V
Sbjct: 2473 SV 2474
Score = 48.1 bits (113), Expect = 1e-05
Identities = 70/291 (24%), Positives = 105/291 (36%), Gaps = 58/291 (19%)
Query: 50 LYCDVVGSPTPEIQWW--YAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLT 107
L CD G P P I W + + ++S R+ +G S L+I R
Sbjct: 3171 LTCDATGIPPPTIAWLKNHKRIENSDSLEV--------RIL-------SGGSKLQIARSQ 3215
Query: 108 LEDSGTYECRASNDPKRN------DLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDS 161
DSG Y C ASN + ++ PS+ + +SVL
Sbjct: 3216 HSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGEN------------ 3263
Query: 162 PVLPVTLQCNLTSSSHTLTYSYWTKNGV-----ELSATRKNASNMEYRINKPRAEDSGEY 216
V L CN L W K+G E R +A+ I D+G+Y
Sbjct: 3264 ----VELVCNANGIPTPLI--QWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKY 3317
Query: 217 HCVYHFVSAPKANA-TIEVKAAPDITGHKRSENK---NEGQDATMYCKSVGYPHPDWIWR 272
CV + + + V P I G+K K + C++ G P P W
Sbjct: 3318 TCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWL 3377
Query: 273 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 323
K NG+P+ + ++ R + + IV Q++ D Y C A+N G
Sbjct: 3378 K--NGLPLPL-SSHIRLLAAGQ----VIRIVRAQVS-DVAVYTCVASNRAG 3420
Score = 47.8 bits (112), Expect = 2e-05
Identities = 66/288 (22%), Positives = 103/288 (35%), Gaps = 39/288 (13%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G ++ C+ G+P P I W L DG + SN L I
Sbjct: 1185 GQRVDIPCNAQGTPLPVITW------SKGGSTMLVDGEH---------HVSNPDGTLSID 1229
Query: 105 RLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVL 164
+ T D+G Y C A+N + + ++ T+ L+ P T +E +
Sbjct: 1230 QATPSDAGIYTCVATNIAGTD---ETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEF 1286
Query: 165 PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME----YRINKPRAEDSGEYHCV- 219
P + + T+ W NG EL+ S +E I D+GEY CV
Sbjct: 1287 PCPAK---GTPKPTIK---WLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVA 1340
Query: 220 YHFVSAPKANATIEVKAAPDITGHKRSENKNE--GQDATMYCKSVGYPHPDWIWRKKENG 277
+ + ++V P I ++ N + Q ++C+ G P P +W K
Sbjct: 1341 VNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYK---- 1396
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSA 325
D V + I N L + ED G Y C A N G++
Sbjct: 1397 ---DNVQVTESSTIQTVNNGKILKLFR-ATPEDAGRYSCKAINIAGTS 1440
Score = 47.0 bits (110), Expect = 3e-05
Identities = 70/318 (22%), Positives = 107/318 (33%), Gaps = 73/318 (22%)
Query: 43 LTGDAFELYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSV 100
L + + C G+P P+I W + + R L G V
Sbjct: 3355 LVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG-----------------QV 3397
Query: 101 LRITRLTLEDSGTYECRASN---------------DPKRNDLRQNPSITWIRAQATISVL 145
+RI R + D Y C ASN P ++ IT ++ +T
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMAC 3457
Query: 146 QKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRI 205
+RD P+ L +LT S+H M ++
Sbjct: 3458 ITDGTPAPSMAWLRDGQ--PLGLDAHLTVSTH----------------------GMVLQL 3493
Query: 206 NKPRAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNE--GQDATMYCKSV 262
K EDSG+Y C+ + + ++V P I G + E + + C +
Sbjct: 3494 LKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIAS 3553
Query: 263 GYPHPDWIWRKKENGMPM-DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNA 321
G P P W K +P D V T G + L I Q+ ED G Y C A++
Sbjct: 3554 GIPAPKMTWMKDGRPLPQTDQVQTLGGGEV--------LRISTAQV-EDTGRYTCLASSP 3604
Query: 322 IGSASVVTVLRVRSHLAP 339
G ++RV H+ P
Sbjct: 3605 AGDDDKEYLVRV--HVPP 3620
Score = 45.4 bits (106), Expect = 9e-05
Identities = 77/361 (21%), Positives = 131/361 (36%), Gaps = 75/361 (20%)
Query: 32 GFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGAR-KRRVTVN 90
G + +P+++ + + L C G+P+P + W L DG K +
Sbjct: 1643 GNLATPLNKQVVIAHSLTLECKAAGNPSPILTW-------------LKDGVPVKANDNIR 1689
Query: 91 TAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI 150
G + ++ + D G Y C A++ +++ + VL P I
Sbjct: 1690 IEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYE-----------VDVLVPPAI 1735
Query: 151 VTSEEV---IIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGV---ELSATRKNASNMEYR 204
+E I+ + +L L C++T S W K+G E + + +
Sbjct: 1736 EGGDETSYFIVMVNNLL--ELDCHVTGSPPPTI--MWLKDGQLIDERDGFKILLNGRKLV 1791
Query: 205 INKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENKNEG---------QDA 255
I + + ++G Y C+ AN + K ++T H K+ G +
Sbjct: 1792 IAQAQVSNTGLYRCM-------AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPV 1844
Query: 256 TMYCKSVGYPHPDWIWRKKENGMPMDI------VNTSGRFFIINKENYTELNIVNLQITE 309
+ C + G P+P W K + P++ + +SGR I K + E
Sbjct: 1845 ALQCIANGIPNPSITWLKDD--QPVNTAQGNLKIQSSGRVLQIAK-----------TLLE 1891
Query: 310 DPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKRPDEV 369
D G Y C ATNA G L V H P G + +LV V E + + V
Sbjct: 1892 DAGRYTCVATNAAGETQQHIQLHV--HEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPV 1949
Query: 370 P 370
P
Sbjct: 1950 P 1950
Score = 45.1 bits (105), Expect = 1e-04
Identities = 77/307 (25%), Positives = 103/307 (33%), Gaps = 51/307 (16%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
P S L + L C G PTP I W DGA + N
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITW-------------RKDGAVLAGNHARYSILEN 3765
Query: 97 GVSVLRITRLTLEDSGTYECRASN----DPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
G L I + D+G Y C A+N D +R DL + S+ P T
Sbjct: 3766 G--FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDL---------QVHVPPSIAPGP---T 3811
Query: 153 SEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKN-----ASNMEYRINK 207
+ VI+ + TL C T W KNG L+ + S+ I
Sbjct: 3812 NMTVIVN----VQTTLACEATGIPKPSI--NWRKNGHLLNVDQNQNSYRLLSSGSLVIIS 3865
Query: 208 PRAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
P +D+ Y C V + K + V+ P I + A + C + G P
Sbjct: 3866 PSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPF 3925
Query: 267 PDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
P W K NG+ + G + I E+ L G Y C A NA GSA
Sbjct: 3926 PSIHWTK--NGIRL---LPRGDGYRILSSGAIEILATQL---NHAGRYTCVARNAAGSAH 3977
Query: 327 VVTVLRV 333
L V
Sbjct: 3978 RHVTLHV 3984
Score = 38.5 bits (88), Expect = 0.011
Identities = 71/295 (24%), Positives = 108/295 (36%), Gaps = 62/295 (21%)
Query: 50 LYCDVVGSPTPEIQWWY-AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTL 108
L C+V G+P PEI W + + + + G R L+IT + +
Sbjct: 2499 LTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR----------------FLQITNVQV 2542
Query: 109 EDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTL 168
+G Y C AS+ + ++ A + P VT VI+ P +L
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVT---VILNS----PTSL 2595
Query: 169 QCNLTS-SSHTLTYSYWTKNGVELSATRK---NASNMEYRINKPRAEDSGEYHCVYHFVS 224
C S T+T W K+G L + R +I + +++G Y C V+
Sbjct: 2596 VCEAYSYPPATIT---WFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSC----VA 2648
Query: 225 APKANATI---EVKA-------APDITGHKRSENK---NEGQDATMYCKSVGYPHPDWIW 271
+A I EVK D+ G S + T+ C++ P W
Sbjct: 2649 TNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSW 2708
Query: 272 RKKENGMPM---DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 323
K +G P+ D VN + N L I QI+ D G Y C A+N G
Sbjct: 2709 YK--DGQPLKSDDHVNIAA--------NGHTLQIKEAQIS-DTGRYTCVASNIAG 2752
Score = 37.0 bits (84), Expect = 0.031
Identities = 68/315 (21%), Positives = 124/315 (39%), Gaps = 47/315 (14%)
Query: 36 SPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGS 95
+P T + L C+ P I W + + ES R + R+
Sbjct: 2581 NPEDVTVILNSPTSLVCEAYSYPPATITW-FKDGTPLESNRNI-------RILP------ 2626
Query: 96 NGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEE 155
G L+I +++G Y C A+N+ ++ +I L P + + +E
Sbjct: 2627 -GGRTLQILNAQEDNAGRYSCVATNEAGEM-IKHYEVKVYIPPIINKGDLWGPGL-SPKE 2683
Query: 156 VIIRDSPVLPVTLQCNLTS-SSHTLTYSYWTKNGVELSA---TRKNASNMEYRINKPRAE 211
V I+ + L TL+C + S +L+ W K+G L + A+ +I + +
Sbjct: 2684 VKIKVNNTL--TLECEAYAIPSASLS---WYKDGQPLKSDDHVNIAANGHTLQIKEAQIS 2738
Query: 212 DSGEYHCVYHFVSAP-KANATIEVKAAPDIT-----GHKRSENKN-EGQDA------TMY 258
D+G Y CV ++ + + + ++ P G+ +N E +D ++Y
Sbjct: 2739 DTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 259 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 318
C++ P P W K +G P+ +S + I+ ++ + ED G Y C A
Sbjct: 2799 CETNAAPPPTLTWYK--DGHPL---TSSDKVLILPGGRVLQIPRAKV---EDAGRYTCVA 2850
Query: 319 TNAIGSASVVTVLRV 333
N G S+ +RV
Sbjct: 2851 VNEAGEDSLQYDVRV 2865
Score = 31.2 bits (69), Expect = 1.7
Identities = 33/155 (21%), Positives = 59/155 (38%), Gaps = 12/155 (7%)
Query: 184 WTKNGVELSATR--KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDI 240
+ +NGV L + K ++++ I K D G Y C+ +A +V P +
Sbjct: 463 FVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPV 522
Query: 241 TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYT-E 299
+ G+ A + C + + W++ + V + I N + E
Sbjct: 523 IQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRD-----VRLAEPARIRTLANLSLE 577
Query: 300 LNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
L V D GEY C ++ GS++ L V+
Sbjct: 578 LKSVKFN---DAGEYHCMVSSEGGSSAASVFLTVQ 609
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 69.7 bits (169), Expect = 4e-12
Identities = 99/392 (25%), Positives = 148/392 (37%), Gaps = 52/392 (13%)
Query: 18 SGSLLPGPGAAQNAG---FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAES 74
SGS++ AG F+ S T GD L C+V+G P P I W ++
Sbjct: 124 SGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHW-------QKN 176
Query: 75 FRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSIT 134
+ L RV V + L+I+RL D G Y C A +NP+ +
Sbjct: 177 QQDLTPIPGDSRVVVLPS------GALQISRLQPGDIGIYRCSA----------RNPASS 220
Query: 135 WIRAQATISVLQKPRIVTSEEVIIRDSPVLPV-----TLQCNLTSSSHTLTYSYWTKNGV 189
+A + +L P + + R S V+ + L+C + S + W +
Sbjct: 221 RTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCV--SGYPPPSFTWLRGEE 278
Query: 190 ELSATRKNAS---NMEYRINKPRAEDSGEYHCVYHFVSAP-KANATIEVKAAPDITGHKR 245
+ K S I+ +DSG Y CV + + A+A + V P H
Sbjct: 279 VIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPS 338
Query: 246 SENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNL 305
+ E D C G P P W K NG D+V S F I+ N L +V
Sbjct: 339 NLYAYESMDIEFECTVSGKPVPTVNWMK--NG---DVVIPSDYFQIVGGSNLRILGVVK- 392
Query: 306 QITEDPGEYECNATNAIGSASVVTVLRVRSHLAPLWPFLGILAEIIILVVIIVVYEKRKR 365
D G Y+C A N G+A L V P P +L VV ++V + R
Sbjct: 393 ---SDEGFYQCVAENEAGNAQTSAQLIVPK---PAIPSSSVLPSAPRDVVPVLVSSRFVR 446
Query: 366 PDEVPDA---GPMKTNSTNNHKDKNLRQRNTN 394
P A G ++T + ++ + R+R N
Sbjct: 447 LSWRPPAEAKGNIQTFTVFFSREGDNRERALN 478
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 67.4 bits (163), Expect = 2e-11
Identities = 73/293 (24%), Positives = 120/293 (40%), Gaps = 35/293 (11%)
Query: 44 TGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRI 103
+G+ C G+P PEI W ++ S L D R +G ++R
Sbjct: 247 SGNTVYFTCRAEGNPKPEIIW----IHNNHSL-DLEDDTRLNVF-------DDGTLMIRN 294
Query: 104 TRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPV 163
TR + D G Y+C A N Q+ + + A S + +P+ EV+I S
Sbjct: 295 TRES--DQGVYQCMARNSAGEAKT-QSAMLRYSSLPAKPSFVIQPQ---DTEVLIGTS-- 346
Query: 164 LPVTLQCNLTSSSHTLTYSYWTK-NGVELSATRKNASNMEYRINKPRAEDSGEYHC-VYH 221
TL+C T H L WT+ NG+EL +R A++ + D G + C +
Sbjct: 347 --TTLECMATGHPHPLIT--WTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTCHANN 402
Query: 222 FVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMD 281
+A A I V+A P T + + E C++ G P P +W K +P++
Sbjct: 403 SHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVE 462
Query: 282 IVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
G+ +++ ++ D G+YEC A +++G V L V+
Sbjct: 463 -----GQHTVLSSGTLR----IDRAAQHDQGQYECQAVSSLGVKKVSVQLTVK 506
Score = 59.3 bits (142), Expect = 6e-09
Identities = 81/332 (24%), Positives = 127/332 (38%), Gaps = 55/332 (16%)
Query: 1 MSGSSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLTGDAFELYCDVVGSPTP 60
M+ +S A S +L SL P FV P L G + L C G P P
Sbjct: 306 MARNSAGEAKTQSAMLRYSSLPAKPS------FVIQPQDTEVLIGTSTTLECMATGHPHP 359
Query: 61 EIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASN 120
I W N E DG+R V T+ G L + +T D G + C A+N
Sbjct: 360 LITW--TRDNGLE-----LDGSRH----VATSSG------LYLQNITQRDHGRFTCHANN 402
Query: 121 DPKRNDLRQNPSITWIRAQATISVLQKPR--IVTSEEVIIRDSPVLPVTLQCNLTSSSHT 178
S ++A A I V P+ + ++V++ + V + + +
Sbjct: 403 -----------SHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAV-----EWLCEADGNP 446
Query: 179 LTYSYWTKNGVELSATRKNA--SNMEYRINKPRAEDSGEYHCVYHF---VSAPKANATIE 233
WTK G +L ++ S+ RI++ D G+Y C V T++
Sbjct: 447 PPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVK 506
Query: 234 VKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIIN 293
KA T + + G++ + C + G P P W K+ G+ + SG+F + +
Sbjct: 507 PKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKE--GVQ---ITESGKFHVDD 561
Query: 294 KENYTELNIVNLQITEDPGEYECNATNAIGSA 325
+ T + D G YEC A N+ G A
Sbjct: 562 EGTLTIYDAG----FPDQGRYECVARNSFGLA 589
Score = 30.4 bits (67), Expect = 2.9
Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 21/102 (20%)
Query: 237 APDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 296
+P IT + G C++ G P P+ IW + + + E+
Sbjct: 233 SPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDL--------------ED 278
Query: 297 YTELNIVN---LQI----TEDPGEYECNATNAIGSASVVTVL 331
T LN+ + L I D G Y+C A N+ G A + +
Sbjct: 279 DTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAM 320
>gi|38348215 embigin [Homo sapiens]
Length = 327
Score = 67.0 bits (162), Expect = 3e-11
Identities = 65/249 (26%), Positives = 101/249 (40%), Gaps = 29/249 (11%)
Query: 166 VTLQCNLTSSSHTLTYSY-WTKNGVEL------SATRKNASNMEYRINKPRAEDSGEYHC 218
V L C T+S + W K+G +L SAT +YR ++ G Y C
Sbjct: 84 VNLTCQFTTSGDLNAVNVTWKKDGEQLENNYLVSATGSTLYT-QYRFTIINSKQMGSYSC 142
Query: 219 VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 278
+ + +V P++ G + G + CK +W W NG
Sbjct: 143 FFREEKEQRGTFNFKV---PELHGKNKPLISYVGDSTVLTCKCQNCFPLNWTWYSS-NGS 198
Query: 279 PMDIVNTSGRFFIINKENYTELNIVNLQITEDPGE-YECNATNAIGSASVVTVLRVRSHL 337
V ++IN E + Q+ E+ GE Y C A +G + L V S+L
Sbjct: 199 VKVPVGVQMNKYVINGTYANETKLKITQLLEEDGESYWCRALFQLGESEEHIELVVLSYL 258
Query: 338 APLWPFLGILAEIIILVVIIVVYE-----KRKRPDE-----------VPDAGPMKTNSTN 381
PL PFL I+AE+I+LV I++ E K+K DE D+ ++ N
Sbjct: 259 VPLKPFLVIVAEVILLVATILLCEKYTQKKKKHSDEGKEFEQIEQLKSDDSNGIENNVPR 318
Query: 382 NHKDKNLRQ 390
+ K+++L Q
Sbjct: 319 HRKNESLGQ 327
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 65.5 bits (158), Expect = 8e-11
Identities = 76/316 (24%), Positives = 122/316 (38%), Gaps = 38/316 (12%)
Query: 29 QNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVT 88
Q F +P + G+ + CDVV S P I W + R + R +
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKG-------RDVILKKDVRFIV 168
Query: 89 VNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKP 148
++ Y L+I + D GTY C + I + Q ++V P
Sbjct: 169 LSNNY-------LQIRGIKKTDEGTYRCEGR-------ILARGEINFKDIQVIVNV---P 211
Query: 149 RIVTSEEVIIRDSPVL--PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNAS------N 200
+ + + I+ + L VTL C+ T S WTK+G ++ + +
Sbjct: 212 PTIQARQNIVNATANLGQSVTLVCDAEGFPEP-TMS-WTKDGEQIEQEEDDEKYIFSDDS 269
Query: 201 MEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVK--AAPDITGHKRSENKNEGQDATMY 258
+ I K D EY C+ A + +ATI +K A P IT + + T+
Sbjct: 270 SQLTIKKVDKNDEAEYICIAEN-KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLT 328
Query: 259 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 318
C++ G P P WR + + G + + + L + ++Q T D GEY C A
Sbjct: 329 CEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYT-DAGEYICTA 387
Query: 319 TNAIGSASVVTVLRVR 334
+N IG S L V+
Sbjct: 388 SNTIGQDSQSMYLEVQ 403
Score = 52.0 bits (123), Expect = 9e-07
Identities = 70/314 (22%), Positives = 113/314 (35%), Gaps = 60/314 (19%)
Query: 38 MSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNG 97
++ T G + L CD G P P + W E Q D + S+
Sbjct: 221 VNATANLGQSVTLVCDAEGFPEPTMSW----TKDGEQIEQEEDDEKY--------IFSDD 268
Query: 98 VSVLRITRLTLEDSGTYECRASNDPKRNDLR------QNPSITWIRAQATISVLQKPRIV 151
S L I ++ D Y C A N D P IT++ Q + L++ +
Sbjct: 269 SSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAME-LEEQVTL 327
Query: 152 TSEEVIIRDSPVLPVTLQC---NLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKP 208
T E P+ +T + N++S TL ++ +S+ +++Y
Sbjct: 328 TCEA---SGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSL--TLKSIQYT---- 378
Query: 209 RAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHP 267
D+GEY C + + + +EV+ AP + G EG + C+ YP
Sbjct: 379 ---DAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSA 434
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVN------LQITEDP----GEYECN 317
W + +P NY+ + I N L++T D G Y C
Sbjct: 435 TISWFRDGQLLP--------------SSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCT 480
Query: 318 ATNAIGSASVVTVL 331
A N IG S+ +L
Sbjct: 481 AVNRIGQESLEFIL 494
Score = 43.9 bits (102), Expect = 3e-04
Identities = 35/156 (22%), Positives = 61/156 (39%), Gaps = 16/156 (10%)
Query: 170 CNLTSSSHTLTYSYWTKNGVELSATRKNAS-------NMEYRINKPRAEDSGEYHCVYHF 222
C + + S+++ NG +L+ ++ S + I +D+G Y CV
Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTG 100
Query: 223 VSAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 280
++ AT+ VK + + EG+DA + C V P IW+ K
Sbjct: 101 EDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGR---- 156
Query: 281 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 316
D++ FI+ NY ++ + D G Y C
Sbjct: 157 DVILKKDVRFIVLSNNYLQIRGIK---KTDEGTYRC 189
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 65.5 bits (158), Expect = 8e-11
Identities = 76/316 (24%), Positives = 122/316 (38%), Gaps = 38/316 (12%)
Query: 29 QNAGFVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVT 88
Q F +P + G+ + CDVV S P I W + R + R +
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKG-------RDVILKKDVRFIV 168
Query: 89 VNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKP 148
++ Y L+I + D GTY C + I + Q ++V P
Sbjct: 169 LSNNY-------LQIRGIKKTDEGTYRCEGR-------ILARGEINFKDIQVIVNV---P 211
Query: 149 RIVTSEEVIIRDSPVL--PVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNAS------N 200
+ + + I+ + L VTL C+ T S WTK+G ++ + +
Sbjct: 212 PTIQARQNIVNATANLGQSVTLVCDAEGFPEP-TMS-WTKDGEQIEQEEDDEKYIFSDDS 269
Query: 201 MEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVK--AAPDITGHKRSENKNEGQDATMY 258
+ I K D EY C+ A + +ATI +K A P IT + + T+
Sbjct: 270 SQLTIKKVDKNDEAEYICIAEN-KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLT 328
Query: 259 CKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNA 318
C++ G P P WR + + G + + + L + ++Q T D GEY C A
Sbjct: 329 CEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYT-DAGEYICTA 387
Query: 319 TNAIGSASVVTVLRVR 334
+N IG S L V+
Sbjct: 388 SNTIGQDSQSMYLEVQ 403
Score = 52.0 bits (123), Expect = 9e-07
Identities = 70/314 (22%), Positives = 113/314 (35%), Gaps = 60/314 (19%)
Query: 38 MSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNG 97
++ T G + L CD G P P + W E Q D + S+
Sbjct: 221 VNATANLGQSVTLVCDAEGFPEPTMSW----TKDGEQIEQEEDDEKY--------IFSDD 268
Query: 98 VSVLRITRLTLEDSGTYECRASNDPKRNDLR------QNPSITWIRAQATISVLQKPRIV 151
S L I ++ D Y C A N D P IT++ Q + L++ +
Sbjct: 269 SSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAME-LEEQVTL 327
Query: 152 TSEEVIIRDSPVLPVTLQC---NLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKP 208
T E P+ +T + N++S TL ++ +S+ +++Y
Sbjct: 328 TCEA---SGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSL--TLKSIQYT---- 378
Query: 209 RAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHP 267
D+GEY C + + + +EV+ AP + G EG + C+ YP
Sbjct: 379 ---DAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTW-EGNQVNITCEVFAYPSA 434
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVN------LQITEDP----GEYECN 317
W + +P NY+ + I N L++T D G Y C
Sbjct: 435 TISWFRDGQLLP--------------SSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCT 480
Query: 318 ATNAIGSASVVTVL 331
A N IG S+ +L
Sbjct: 481 AVNRIGQESLEFIL 494
Score = 43.9 bits (102), Expect = 3e-04
Identities = 35/156 (22%), Positives = 61/156 (39%), Gaps = 16/156 (10%)
Query: 170 CNLTSSSHTLTYSYWTKNGVELSATRKNAS-------NMEYRINKPRAEDSGEYHCVYHF 222
C + + S+++ NG +L+ ++ S + I +D+G Y CV
Sbjct: 41 CQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTG 100
Query: 223 VSAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPM 280
++ AT+ VK + + EG+DA + C V P IW+ K
Sbjct: 101 EDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGR---- 156
Query: 281 DIVNTSGRFFIINKENYTELNIVNLQITEDPGEYEC 316
D++ FI+ NY ++ + D G Y C
Sbjct: 157 DVILKKDVRFIVLSNNYLQIRGIK---KTDEGTYRC 189
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 65.1 bits (157), Expect = 1e-10
Identities = 80/303 (26%), Positives = 110/303 (36%), Gaps = 54/303 (17%)
Query: 34 VKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAY 93
V+ P + G +L C +G+P P I W A+ ARK R +
Sbjct: 229 VQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPI---------ARKAR-----RH 274
Query: 94 GSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSI----TWIRAQATISVLQKPR 149
SNG+ L I ED+G YEC A N +N R + WI+ I V +
Sbjct: 275 KSNGI--LEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAMEEN 332
Query: 150 IVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVE-LSATRKNASNMEYRINKP 208
+ + R P TY W KNG L+ R I
Sbjct: 333 VFWECKANGRPKP-----------------TYK-WLKNGEPLLTRDRIQIEQGTLNITIV 374
Query: 209 RAEDSGEYHCV---YHFVSAPKANATIEVKAAPDI--TGHKRSENKNEGQDATMYCKSVG 263
D+G Y C+ H V A ++ + PD T KR G + + CK
Sbjct: 375 NLSDAGMYQCLAENKHGVIFSNAELSV-IAVGPDFSRTLLKRVTLVKVGGEVVIECKPKA 433
Query: 264 YPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 323
P P + W+K DI+ + R I N +N+ D G Y C ATN G
Sbjct: 434 SPKPVYTWKKGR-----DILKENERITISEDGNLRIINVTK----SDAGSYTCIATNHFG 484
Query: 324 SAS 326
+AS
Sbjct: 485 TAS 487
Score = 47.4 bits (111), Expect = 2e-05
Identities = 86/327 (26%), Positives = 120/327 (36%), Gaps = 56/327 (17%)
Query: 14 LLLVSGSLLPGPGAAQNAGFVKSPM-SETKLTGDAFELYCDVVGSPTPEIQWWY--AEVN 70
L L S L GP Q V P+ SE K +L C+V G+P P I+W +V+
Sbjct: 15 LCLADDSTLHGPIFIQEPSPVMFPLDSEEKKV----KLNCEVKGNPKPHIRWKLNGTDVD 70
Query: 71 RAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQN 130
FR Y S+L +D+GTY+C A+N
Sbjct: 71 TGMDFR----------------YSVVEGSLLINNPNKTQDAGTYQCTATN--------SF 106
Query: 131 PSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVE 190
+I A+ + L + T V +R + L C S L+Y++
Sbjct: 107 GTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQ--GMVLLCGPPPHSGELSYAWIFNEYPS 164
Query: 191 LSATRKNASNM--EYRINKPRAEDSGEYHCVY------HFVSAPKA-----NATIEVKAA 237
R+ S I K D G Y CV H V P N + +
Sbjct: 165 YQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYE 224
Query: 238 PDI-TGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKEN 296
P I + +G + C ++G P P IWR+ + G P I + R +K N
Sbjct: 225 PKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRAD-GKP--IARKARR----HKSN 277
Query: 297 YTELNIVNLQITEDPGEYECNATNAIG 323
L I N Q ED G YEC A N+ G
Sbjct: 278 GI-LEIPNFQ-QEDAGLYECVAENSRG 302
Score = 33.5 bits (75), Expect = 0.34
Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 7/75 (9%)
Query: 250 NEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITE 309
+E + + C+ G P P W K NG +D R+ ++ L I N T+
Sbjct: 41 SEEKKVKLNCEVKGNPKPHIRW--KLNGTDVD-TGMDFRYSVVEGS----LLINNPNKTQ 93
Query: 310 DPGEYECNATNAIGS 324
D G Y+C ATN+ G+
Sbjct: 94 DAGTYQCTATNSFGT 108
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 64.7 bits (156), Expect = 1e-10
Identities = 79/336 (23%), Positives = 119/336 (35%), Gaps = 72/336 (21%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVN 90
F P S+ + C+V G P PE+ W+ V R E ++++ A
Sbjct: 416 FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA-------- 467
Query: 91 TAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI 150
G L + + DSGTY C ASN + S +W ++V++ +
Sbjct: 468 ------GSHYLCLLKARTRDSGTYSCTASN------AQGQLSCSWTLQVERLAVME---V 512
Query: 151 VTSEEVIIRDSPVL---PVTLQCNLTSSSHTLTYSYWTKNGVELSATRK--NASNMEYRI 205
S +++D V+ LQC++ + + W NG + R A E I
Sbjct: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGT--PVPRITWLLNGQPIQYARSTCEAGVAELHI 570
Query: 206 NKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGH-KRSENKNE------------- 251
ED G Y C+ NA +V + +T H K+S K+E
Sbjct: 571 QDALPEDHGTYTCL-------AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 623
Query: 252 -------------GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYT 298
G TM + G P P+ IW N + S F +
Sbjct: 624 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE-----IQESEDFHFEQRGTQH 678
Query: 299 ELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
L I + ED G Y C A N+ G VL V+
Sbjct: 679 SLCIQEV-FPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
Query: 251 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 310
EG A + GYP P W + NG P + + GRF + T +++ ED
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHR--NGQP---ITSGGRFLLDCGIRGTFSLVIHAVHEED 100
Query: 311 PGEYECNATNAIGSASVVTVLRVRSHLA 338
G+Y C ATN G+ V L V A
Sbjct: 101 RGKYTCEATNGSGARQVTVELTVEGSFA 128
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 5/85 (5%)
Query: 251 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 310
EG A CK GYP P+ +W K + + S F I E+ I++ +D
Sbjct: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQS-----IRESRHFQIDYDEDGNCSLIISDVCGDD 1825
Query: 311 PGEYECNATNAIGSASVVTVLRVRS 335
+Y C A N++G A+ L V +
Sbjct: 1826 DAKYTCKAVNSLGEATCTAELIVET 1850
Score = 34.3 bits (77), Expect = 0.20
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 6/84 (7%)
Query: 251 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 310
EGQ CK G P P W K +P+ S R + K L I + +D
Sbjct: 174 EGQMGRFSCKITGRPQPQVTWLK--GNVPL---QPSARVSVSEKNGMQVLEIHGVN-QDD 227
Query: 311 PGEYECNATNAIGSASVVTVLRVR 334
G Y C N G AS+ L ++
Sbjct: 228 VGVYTCLVVNGSGKASMSAELSIQ 251
Score = 31.6 bits (70), Expect = 1.3
Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 13/82 (15%)
Query: 52 CDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDS 111
C + G P P++ W V S RV+V+ NG+ VL I + +D
Sbjct: 182 CKITGRPQPQVTWLKGNVPLQPS----------ARVSVSE---KNGMQVLEIHGVNQDDV 228
Query: 112 GTYECRASNDPKRNDLRQNPSI 133
G Y C N + + SI
Sbjct: 229 GVYTCLVVNGSGKASMSAELSI 250
Score = 28.9 bits (63), Expect = 8.4
Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 12/76 (15%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G A C + G P PE+ W+ + + ES R ++ Y +G L I+
Sbjct: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRES----------RHFQID--YDEDGNCSLIIS 1819
Query: 105 RLTLEDSGTYECRASN 120
+ +D Y C+A N
Sbjct: 1820 DVCGDDDAKYTCKAVN 1835
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 64.7 bits (156), Expect = 1e-10
Identities = 79/336 (23%), Positives = 119/336 (35%), Gaps = 72/336 (21%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVN 90
F P S+ + C+V G P PE+ W+ V R E ++++ A
Sbjct: 416 FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA-------- 467
Query: 91 TAYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRI 150
G L + + DSGTY C ASN + S +W ++V++ +
Sbjct: 468 ------GSHYLCLLKARTRDSGTYSCTASN------AQGQLSCSWTLQVERLAVME---V 512
Query: 151 VTSEEVIIRDSPVL---PVTLQCNLTSSSHTLTYSYWTKNGVELSATRK--NASNMEYRI 205
S +++D V+ LQC++ + + W NG + R A E I
Sbjct: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGT--PVPRITWLLNGQPIQYARSTCEAGVAELHI 570
Query: 206 NKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGH-KRSENKNE------------- 251
ED G Y C+ NA +V + +T H K+S K+E
Sbjct: 571 QDALPEDHGTYTCL-------AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 623
Query: 252 -------------GQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYT 298
G TM + G P P+ IW N + S F +
Sbjct: 624 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE-----IQESEDFHFEQRGTQH 678
Query: 299 ELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVR 334
L I + ED G Y C A N+ G VL V+
Sbjct: 679 SLCIQEV-FPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
Query: 251 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 310
EG A + GYP P W + NG P + + GRF + T +++ ED
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHR--NGQP---ITSGGRFLLDCGIRGTFSLVIHAVHEED 100
Query: 311 PGEYECNATNAIGSASVVTVLRVRSHLA 338
G+Y C ATN G+ V L V A
Sbjct: 101 RGKYTCEATNGSGARQVTVELTVEGSFA 128
Score = 40.4 bits (93), Expect = 0.003
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 5/85 (5%)
Query: 251 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 310
EG A CK GYP P+ +W K + + S F I E+ I++ +D
Sbjct: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQS-----IRESRHFQIDYDEDGNCSLIISDVCGDD 1876
Query: 311 PGEYECNATNAIGSASVVTVLRVRS 335
+Y C A N++G A+ L V +
Sbjct: 1877 DAKYTCKAVNSLGEATCTAELIVET 1901
Score = 34.3 bits (77), Expect = 0.20
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 6/84 (7%)
Query: 251 EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITED 310
EGQ CK G P P W K +P+ S R + K L I + +D
Sbjct: 174 EGQMGRFSCKITGRPQPQVTWLK--GNVPL---QPSARVSVSEKNGMQVLEIHGVN-QDD 227
Query: 311 PGEYECNATNAIGSASVVTVLRVR 334
G Y C N G AS+ L ++
Sbjct: 228 VGVYTCLVVNGSGKASMSAELSIQ 251
Score = 31.6 bits (70), Expect = 1.3
Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 13/82 (15%)
Query: 52 CDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLEDS 111
C + G P P++ W V S RV+V+ NG+ VL I + +D
Sbjct: 182 CKITGRPQPQVTWLKGNVPLQPS----------ARVSVSE---KNGMQVLEIHGVNQDDV 228
Query: 112 GTYECRASNDPKRNDLRQNPSI 133
G Y C N + + SI
Sbjct: 229 GVYTCLVVNGSGKASMSAELSI 250
Score = 28.9 bits (63), Expect = 8.4
Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 12/76 (15%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G A C + G P PE+ W+ + + ES R ++ Y +G L I+
Sbjct: 1823 GSAARFDCKIEGYPDPEVVWFKDDQSIRES----------RHFQID--YDEDGNCSLIIS 1870
Query: 105 RLTLEDSGTYECRASN 120
+ +D Y C+A N
Sbjct: 1871 DVCGDDDAKYTCKAVN 1886
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 64.3 bits (155), Expect = 2e-10
Identities = 64/302 (21%), Positives = 114/302 (37%), Gaps = 45/302 (14%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G ++ C G PTP I W + + ++ + L I
Sbjct: 505 GVEVKVSCSASGYPTPHISW----------------SRESQALQEDSRIHVDAQGTLIIQ 548
Query: 105 RLTLEDSGTYECRASNDPKRND------LRQNPSITWIRAQATISVLQKPRIVTSEEVII 158
+ ED+G Y C+A+N+ + PS++ + A ++V + E V++
Sbjct: 549 GVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGE-------EAVLV 601
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHC 218
++ +P W + G+E+ + +S+ + RI + D+G Y C
Sbjct: 602 CEASGVPPPRVI-------------WYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTC 648
Query: 219 -VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENG 277
+ + A + V AP +T R G+ A + C++ G P P WR+ + G
Sbjct: 649 RAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGD-G 707
Query: 278 MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHL 337
P+ + +GR + + L ++ ED Y C A N G L V H
Sbjct: 708 QPLGLRLGAGRGSRSRQPDSGVLFFESV-APEDQAPYVCEARNVFGKVQAEARLIVTGHA 766
Query: 338 AP 339
P
Sbjct: 767 PP 768
Score = 63.5 bits (153), Expect = 3e-10
Identities = 68/294 (23%), Positives = 111/294 (37%), Gaps = 33/294 (11%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
P T G + L C G P P + W + G+R R+
Sbjct: 675 PRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQ---------P 725
Query: 97 GVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVL-QKPRIVTSEE 155
VL + ED Y C A N ++A+A + V P + S
Sbjct: 726 DSGVLFFESVAPEDQAPYVCEARN-----------VFGKVQAEARLIVTGHAPPQIASSA 774
Query: 156 VIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRA--EDS 213
+R PV+L C + + L +W K+G L +++ + ++ RA E +
Sbjct: 775 PTVRVLEGQPVSLPC-IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHA 833
Query: 214 GEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 272
G Y CV + + + + V+ P I NEG A++ C + G P P W
Sbjct: 834 GRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWT 893
Query: 273 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSAS 326
K+ N + + G + ++KE ++ +D G Y C ATN +G +S
Sbjct: 894 KETNAL-----TSRGPHYNVSKEGTL---LIAQPSAQDAGAYVCTATNTVGFSS 939
Score = 62.8 bits (151), Expect = 5e-10
Identities = 60/241 (24%), Positives = 100/241 (41%), Gaps = 37/241 (15%)
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKP-RIV 151
+ +G S I R + + GTYEC A + RA+A I V P ++V
Sbjct: 356 FQESGNSSWEILRASKAEEGTYECTAVSRAGTG-----------RAKAQIVVTDPPPQLV 404
Query: 152 TSEEVIIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRKNAS---NMEYRINK 207
+ V + SP L C L + + LT W ++ L A+ + ++ I+
Sbjct: 405 PAPNVTV--SPGETAVLSCRVLGEAPYNLT---WVRDWRVLPASTGRVAQLADLSLEISG 459
Query: 208 PRAEDSGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
D G Y CV + +A+ + V+ AP ++ H S++ ++G + + C + GYP
Sbjct: 460 IIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPT 519
Query: 267 PDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 323
P W ++ + D V+ G I+ ED G Y C ATN +G
Sbjct: 520 PHISWSRESQALQEDSRIHVDAQGTL------------IIQGVAPEDAGNYSCQATNEVG 567
Query: 324 S 324
+
Sbjct: 568 T 568
Score = 52.4 bits (124), Expect = 7e-07
Identities = 75/305 (24%), Positives = 116/305 (38%), Gaps = 52/305 (17%)
Query: 43 LTGDAFELYCDVV-GSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVL 101
L G L C V+ G P PE W L DG R + + + L
Sbjct: 780 LEGQPVSLPCIVLAGRPLPERHW-------------LKDG---RPLPPGSRHSIRADGSL 823
Query: 102 RITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDS 161
+ R E +G Y C A+N + V PRI + I +
Sbjct: 824 HLDRALQEHAGRYSCVATNTAGSQ-----------HRDVELVVQVPPRIHPTATHHITNE 872
Query: 162 PVLPVTLQCNLTS-SSHTLTYSYWTK--NGVELSATRKNASNM-EYRINKPRAEDSGEYH 217
V P +L C + + T+T WTK N + N S I +P A+D+G Y
Sbjct: 873 GV-PASLPCVASGVPAPTIT---WTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYV 928
Query: 218 CVYHFV---SAPKANATIEVKAAPDITGHKRSE-----NKNEGQDATMYCKSVGYPHPDW 269
C S+ + ++ K + G + + G++ T+ C++ G P P
Sbjct: 929 CTATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKGSPPPLV 988
Query: 270 IWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVT 329
W K +P + R+ ++ + L + +Q+ D G YEC A+N GSAS
Sbjct: 989 TWTKDSRPVPP----ITNRYGLLPSGS---LRLAQVQVG-DSGHYECTASNPAGSASHRY 1040
Query: 330 VLRVR 334
VL V+
Sbjct: 1041 VLGVQ 1045
Score = 37.0 bits (84), Expect = 0.031
Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 15/84 (17%)
Query: 37 PMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSN 96
P+ T G+ L C+ GSP P + W + R + + YG
Sbjct: 963 PLQVTAKAGEEVTLDCEAKGSPPPLVTW-------TKDSRPV--------PPITNRYGLL 1007
Query: 97 GVSVLRITRLTLEDSGTYECRASN 120
LR+ ++ + DSG YEC ASN
Sbjct: 1008 PSGSLRLAQVQVGDSGHYECTASN 1031
Score = 29.3 bits (64), Expect = 6.5
Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 17/144 (11%)
Query: 196 KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQD 254
+ + N + I + + G Y C +A A I V P + + G+
Sbjct: 357 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGET 416
Query: 255 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----ED 310
A + C+ +G + W + +P ++GR +L ++L+I+ D
Sbjct: 417 AVLSCRVLGEAPYNLTWVRDWRVLPA----STGRV--------AQLADLSLEISGIIPTD 464
Query: 311 PGEYECNATNAIGSASVVTVLRVR 334
G Y+C A+NA G L VR
Sbjct: 465 GGRYQCVASNANGVTRASVWLLVR 488
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 63.9 bits (154), Expect = 2e-10
Identities = 74/302 (24%), Positives = 119/302 (39%), Gaps = 38/302 (12%)
Query: 39 SETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGV 98
S+ G EL C G P P I+W L DG R + ++ + + +
Sbjct: 294 SQEVWAGHTVELPCTASGYPIPAIRW-------------LKDG---RPLPADSRW-TKRI 336
Query: 99 SVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQAT-ISVLQKPRIVTSEEVI 157
+ L I+ L EDSGTY C +N T+ A+AT I ++ P VT
Sbjct: 337 TGLTISDLRTEDSGTYICEVTN-------------TFGSAEATGILMVIDPLHVTLTPKK 383
Query: 158 IRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVEL---SATRKNASNMEYRINKPRAEDSG 214
++ V L C LT S T ++ + L + + + SN I + SG
Sbjct: 384 LKTGIGSTVILSCALTGSPE-FTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSG 442
Query: 215 EYHC-VYHFVSAPKANATIEVK-AAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWR 272
Y C + A I ++ P I + N G+ ++ C + G P P W
Sbjct: 443 AYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWA 502
Query: 273 KKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 332
+ + D + + ++ + + + +N+ QI D G Y C A N +GSA +
Sbjct: 503 LDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQI-RDGGVYRCTARNLVGSAEYQARIN 561
Query: 333 VR 334
VR
Sbjct: 562 VR 563
Score = 45.8 bits (107), Expect = 7e-05
Identities = 70/286 (24%), Positives = 112/286 (39%), Gaps = 51/286 (17%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVS--VLR 102
G L C + GSP I+W+ V + A G+S L
Sbjct: 389 GSTVILSCALTGSPEFTIRWY----------------RNTELVLPDEAISIRGLSNETLL 432
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS--EEVIIRD 160
IT SG Y+C A+ ++ Q+ +I + PRIV+S E+V+
Sbjct: 433 ITSAQKSHSGAYQCFAT---RKAQTAQDFAIIALEDGT-------PRIVSSFSEKVV--- 479
Query: 161 SPVLPVTLQCNLTSSSH-TLTYSYWTKNGVELSATRKNASNME-------YRINKPRAED 212
+P +L C + T+T++ + V + R N M + P+ D
Sbjct: 480 NPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRD 539
Query: 213 SGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIW 271
G Y C + V + + A I V+ P I R+ G+D + C+ +GYP+ W
Sbjct: 540 GGVYRCTARNLVGSAEYQARINVRGPPSIRA-MRNITAVAGRDTLINCRVIGYPYYSIKW 598
Query: 272 RKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECN 317
K +P + R + EN T L + ++Q D GEY C+
Sbjct: 599 YKDALLLP-----DNHRQVVF--ENGT-LKLTDVQKGMDEGEYLCS 636
Score = 43.5 bits (101), Expect = 3e-04
Identities = 62/311 (19%), Positives = 118/311 (37%), Gaps = 63/311 (20%)
Query: 34 VKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAY 93
+++ + T + G + C V+G P I+W+ + ++ RQ+
Sbjct: 568 IRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQV--------------V 613
Query: 94 GSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTS 153
NG L + + D G Y C + Q +S+ Q +
Sbjct: 614 FENGTLKLTDVQKGM-DEGEYLCS------------------VLIQPQLSISQSVHVAVK 654
Query: 154 EEVIIRDSPVLPVT------LQCNLTSSSHTLTYSYWTKNG-VELSATRKNASNMEY--- 203
+I+ P + + C ++S + + W K+G V +S + + E+
Sbjct: 655 VPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRIT-WRKDGQVIISGSGVTIESKEFMSS 713
Query: 204 -RINKPRAEDSGEYHCVYHFVSAPKANATIE------VKAAPDITGHKRSENKNEGQDAT 256
+I+ + +G Y C+ A A AT+ V+ P +++ G+
Sbjct: 714 LQISSVSLKHNGNYTCI-----ASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGV 768
Query: 257 MYCKSVGYPHPDWIWR-KKENGMPMDI--VNTSGRFFIINKENYTELNIVNLQITEDPGE 313
+ C GYP P +W+ K +G P V +GR I+ + ++ + ED G
Sbjct: 769 LNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSL----LIRHVLEEDIGY 824
Query: 314 YECNATNAIGS 324
Y C A+N +G+
Sbjct: 825 YLCQASNGVGT 835
Score = 43.1 bits (100), Expect = 4e-04
Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 10/107 (9%)
Query: 227 KANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTS 286
+ + T ++ P I S+ G + C + GYP P W K +P D T
Sbjct: 275 RLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWT- 333
Query: 287 GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
+ T L I +L+ TED G Y C TN GSA +L V
Sbjct: 334 --------KRITGLTISDLR-TEDSGTYICEVTNTFGSAEATGILMV 371
Score = 33.1 bits (74), Expect = 0.45
Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 253 QDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPG 312
+D + C SVG P P W K + + R +I+ L V ED G
Sbjct: 1365 KDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHR--LIHTNGTLLLRAVK---AEDSG 1419
Query: 313 EYECNATNAIGSASVVTVLRVR 334
Y C ATN G +++ L V+
Sbjct: 1420 YYTCTATNTGGFDTIIVNLLVQ 1441
Score = 32.3 bits (72), Expect = 0.76
Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
FV P ++ + G A L C V G P P++ W +A+ + + ++ N
Sbjct: 752 FVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN-- 809
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASN 120
S L I + ED G Y C+ASN
Sbjct: 810 ------SSLLIRHVLEEDIGYYLCQASN 831
Score = 31.2 bits (69), Expect = 1.7
Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 12/71 (16%)
Query: 50 LYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRITRLTLE 109
L C+ VG P P ++W + + + DG R +NG +LR + E
Sbjct: 1369 LPCNSVGDPAPAVKW--TKDSEDSAIPVSMDGHR--------LIHTNGTLLLRAVK--AE 1416
Query: 110 DSGTYECRASN 120
DSG Y C A+N
Sbjct: 1417 DSGYYTCTATN 1427
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 63.5 bits (153), Expect = 3e-10
Identities = 81/308 (26%), Positives = 123/308 (39%), Gaps = 35/308 (11%)
Query: 34 VKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAY 93
V+ P G+ L C G PTP I+ WY + R E+ + D R R+ +
Sbjct: 50 VEHPSDVIVSKGEPTTLNCKAEGRPTPTIE-WYKDGERVETDK---DDPRSHRMLL---- 101
Query: 94 GSNGVSVLRIT--RLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV 151
S + LRI R + D G+Y C A RN L + S A +++L+
Sbjct: 102 PSGSLFFLRIVHGRRSKPDEGSYVCVA-----RNYLGEAVS---RNASLEVALLRDDFRQ 153
Query: 152 TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNAS--NMEYRINKPR 209
+V++ P L+C H YW K+ V + + S + I+ R
Sbjct: 154 NPTDVVVAAGE--PAILECQ-PPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTR 210
Query: 210 AEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENK--NEGQDATMYCKSVGYPHP 267
D+G Y CV + + + E+ T +R N+ E + C+ G P P
Sbjct: 211 KSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQP 270
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASV 327
W+K + +P GR+ I K++YT L I T D G Y C A N +G
Sbjct: 271 TVRWKKDDADLP------RGRYDI--KDDYT-LRIKKTMST-DEGTYMCIAENRVGKMEA 320
Query: 328 VTVLRVRS 335
L VR+
Sbjct: 321 SATLTVRA 328
Score = 56.2 bits (134), Expect = 5e-08
Identities = 77/319 (24%), Positives = 117/319 (36%), Gaps = 58/319 (18%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F++ P+++ L +A E C V G P P ++W + + R +
Sbjct: 243 FLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-----------RYDIKDD 291
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPR-IV 151
Y LRI + D GTY C A N + + A AT++V P+ +V
Sbjct: 292 Y------TLRIKKTMSTDEGTYMCIAEN-----------RVGKMEASATLTVRAPPQFVV 334
Query: 152 TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVE--LSATRKNASNM-------- 201
+ I+ VT C + + W K G + L + N
Sbjct: 335 RPRDQIVAQGRT--VTFPCETKGNPQPAVF--WQKEGSQNLLFPNQPQQPNSRCSVSPTG 390
Query: 202 EYRINKPRAEDSGEYHCVYHFVSAP-KANATIEV------KAAPDITGHKRSENKNEGQD 254
+ I + D+G Y C V+ A A +EV + P I ++
Sbjct: 391 DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGT 450
Query: 255 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEY 314
A + CK+ G P P W K+ P GR + L I NL+I+ D G Y
Sbjct: 451 ALLKCKATGDPLPVISWLKEGFTFP-------GRDPRATIQEQGTLQIKNLRIS-DTGTY 502
Query: 315 ECNATNAIGSASVVTVLRV 333
C AT++ G S VL V
Sbjct: 503 TCVATSSSGETSWSAVLDV 521
Score = 55.5 bits (132), Expect = 8e-08
Identities = 69/309 (22%), Positives = 117/309 (37%), Gaps = 43/309 (13%)
Query: 33 FVKSPMSETKLTGDAFELYCDVV-GSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNT 91
F ++P G+ L C G P P I W +V + ++ R+++
Sbjct: 151 FRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDD---------KEERISIRG 201
Query: 92 AYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV 151
L I+ D+G Y C +N D +P A ++V ++P +
Sbjct: 202 GK-------LMISNTRKSDAGMYTCVGTNMVGERD--SDP--------AELTVFERPTFL 244
Query: 152 TS--EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASN-MEYRINKP 208
+V++ + V +C + W K+ +L R + + RI K
Sbjct: 245 RRPINQVVLEEEAV---EFRCQVQGDPQPTVR--WKKDDADLPRGRYDIKDDYTLRIKKT 299
Query: 209 RAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHP 267
+ D G Y C+ + V +A+AT+ V+A P R + +G+ T C++ G P P
Sbjct: 300 MSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQP 359
Query: 268 DWIWRKKENG---MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 324
W+K+ + P + R + +L I N+Q D G Y C A GS
Sbjct: 360 AVFWQKEGSQNLLFPNQPQQPNSRCSV---SPTGDLTITNIQ-RSDAGYYICQALTVAGS 415
Query: 325 ASVVTVLRV 333
L V
Sbjct: 416 ILAKAQLEV 424
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 1/89 (1%)
Query: 238 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 297
P I H ++G+ T+ CK+ G P P W K + D + ++ +
Sbjct: 47 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 106
Query: 298 TELNIVNLQITE-DPGEYECNATNAIGSA 325
L IV+ + ++ D G Y C A N +G A
Sbjct: 107 FFLRIVHGRRSKPDEGSYVCVARNYLGEA 135
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 63.5 bits (153), Expect = 3e-10
Identities = 81/308 (26%), Positives = 123/308 (39%), Gaps = 35/308 (11%)
Query: 34 VKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAY 93
V+ P G+ L C G PTP I+ WY + R E+ + D R R+ +
Sbjct: 34 VEHPSDVIVSKGEPTTLNCKAEGRPTPTIE-WYKDGERVETDK---DDPRSHRMLL---- 85
Query: 94 GSNGVSVLRIT--RLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV 151
S + LRI R + D G+Y C A RN L + S A +++L+
Sbjct: 86 PSGSLFFLRIVHGRRSKPDEGSYVCVA-----RNYLGEAVS---RNASLEVALLRDDFRQ 137
Query: 152 TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNAS--NMEYRINKPR 209
+V++ P L+C H YW K+ V + + S + I+ R
Sbjct: 138 NPTDVVVAAGE--PAILECQ-PPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTR 194
Query: 210 AEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHKRSENK--NEGQDATMYCKSVGYPHP 267
D+G Y CV + + + E+ T +R N+ E + C+ G P P
Sbjct: 195 KSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQP 254
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASV 327
W+K + +P GR+ I K++YT L I T D G Y C A N +G
Sbjct: 255 TVRWKKDDADLP------RGRYDI--KDDYT-LRIKKTMST-DEGTYMCIAENRVGKMEA 304
Query: 328 VTVLRVRS 335
L VR+
Sbjct: 305 SATLTVRA 312
Score = 56.2 bits (134), Expect = 5e-08
Identities = 77/319 (24%), Positives = 117/319 (36%), Gaps = 58/319 (18%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F++ P+++ L +A E C V G P P ++W + + R +
Sbjct: 227 FLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRG-----------RYDIKDD 275
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPR-IV 151
Y LRI + D GTY C A N + + A AT++V P+ +V
Sbjct: 276 Y------TLRIKKTMSTDEGTYMCIAEN-----------RVGKMEASATLTVRAPPQFVV 318
Query: 152 TSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVE--LSATRKNASNM-------- 201
+ I+ VT C + + W K G + L + N
Sbjct: 319 RPRDQIVAQGRT--VTFPCETKGNPQPAVF--WQKEGSQNLLFPNQPQQPNSRCSVSPTG 374
Query: 202 EYRINKPRAEDSGEYHCVYHFVSAP-KANATIEV------KAAPDITGHKRSENKNEGQD 254
+ I + D+G Y C V+ A A +EV + P I ++
Sbjct: 375 DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGT 434
Query: 255 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEY 314
A + CK+ G P P W K+ P GR + L I NL+I+ D G Y
Sbjct: 435 ALLKCKATGDPLPVISWLKEGFTFP-------GRDPRATIQEQGTLQIKNLRIS-DTGTY 486
Query: 315 ECNATNAIGSASVVTVLRV 333
C AT++ G S VL V
Sbjct: 487 TCVATSSSGETSWSAVLDV 505
Score = 55.5 bits (132), Expect = 8e-08
Identities = 69/309 (22%), Positives = 117/309 (37%), Gaps = 43/309 (13%)
Query: 33 FVKSPMSETKLTGDAFELYCDVV-GSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNT 91
F ++P G+ L C G P P I W +V + ++ R+++
Sbjct: 135 FRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDD---------KEERISIRG 185
Query: 92 AYGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV 151
L I+ D+G Y C +N D +P A ++V ++P +
Sbjct: 186 GK-------LMISNTRKSDAGMYTCVGTNMVGERD--SDP--------AELTVFERPTFL 228
Query: 152 TS--EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASN-MEYRINKP 208
+V++ + V +C + W K+ +L R + + RI K
Sbjct: 229 RRPINQVVLEEEAV---EFRCQVQGDPQPTVR--WKKDDADLPRGRYDIKDDYTLRIKKT 283
Query: 209 RAEDSGEYHCVY-HFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHP 267
+ D G Y C+ + V +A+AT+ V+A P R + +G+ T C++ G P P
Sbjct: 284 MSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQP 343
Query: 268 DWIWRKKENG---MPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS 324
W+K+ + P + R + +L I N+Q D G Y C A GS
Sbjct: 344 AVFWQKEGSQNLLFPNQPQQPNSRCSV---SPTGDLTITNIQ-RSDAGYYICQALTVAGS 399
Query: 325 ASVVTVLRV 333
L V
Sbjct: 400 ILAKAQLEV 408
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 1/89 (1%)
Query: 238 PDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENY 297
P I H ++G+ T+ CK+ G P P W K + D + ++ +
Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90
Query: 298 TELNIVNLQITE-DPGEYECNATNAIGSA 325
L IV+ + ++ D G Y C A N +G A
Sbjct: 91 FFLRIVHGRRSKPDEGSYVCVARNYLGEA 119
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 62.8 bits (151), Expect = 5e-10
Identities = 60/241 (24%), Positives = 100/241 (41%), Gaps = 37/241 (15%)
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKP-RIV 151
+ +G S I R + + GTYEC A + RA+A I V P ++V
Sbjct: 472 FQESGNSSWEILRASKAEEGTYECTAVSRAGTG-----------RAKAQIVVTDPPPQLV 520
Query: 152 TSEEVIIRDSPVLPVTLQCN-LTSSSHTLTYSYWTKNGVELSATRKNAS---NMEYRINK 207
+ V + SP L C L + + LT W ++ L A+ + ++ I+
Sbjct: 521 PAPNVTV--SPGETAVLSCRVLGEAPYNLT---WVRDWRVLPASTGRVAQLADLSLEISG 575
Query: 208 PRAEDSGEYHCVYHFVSA-PKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPH 266
D G Y CV + +A+ + V+ AP ++ H S++ ++G + + C + GYP
Sbjct: 576 IIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPT 635
Query: 267 PDWIWRKKENGMPMDI---VNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 323
P W ++ + D V+ G I+ ED G Y C ATN +G
Sbjct: 636 PHISWSRESQALQEDSRIHVDAQGTL------------IIQGVAPEDAGNYSCQATNEVG 683
Query: 324 S 324
+
Sbjct: 684 T 684
Score = 42.0 bits (97), Expect = 0.001
Identities = 53/241 (21%), Positives = 94/241 (39%), Gaps = 38/241 (15%)
Query: 101 LRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIV--TSEEVII 158
L I+ + D G Y+C ASN +T RA + V + P++ TS +
Sbjct: 571 LEISGIIPTDGGRYQCVASNAN---------GVT--RASVWLLVREAPQVSIHTSSQHFS 619
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYR--INKPRAEDSGEY 216
+ V ++ + ++S + + W++ L + + + I ED+G Y
Sbjct: 620 QG-----VEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNY 674
Query: 217 HC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKE 275
C + V + T+ P ++ G++A + C++ G P P IW +
Sbjct: 675 SCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYR-- 732
Query: 276 NGMPMDIV---NTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLR 332
G+ M + ++SG+ I + D G Y C A N +G AS L
Sbjct: 733 GGLEMILAPEGSSSGKLRIPAAQE------------RDAGTYTCRAVNELGDASAEIQLA 780
Query: 333 V 333
V
Sbjct: 781 V 781
Score = 34.7 bits (78), Expect = 0.15
Identities = 34/180 (18%), Positives = 67/180 (37%), Gaps = 42/180 (23%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLRIT 104
G ++ C G PTP I W + + ++ + L I
Sbjct: 621 GVEVKVSCSASGYPTPHISW----------------SRESQALQEDSRIHVDAQGTLIIQ 664
Query: 105 RLTLEDSGTYECRASNDPKRND------LRQNPSITWIRAQATISVLQKPRIVTSEEVII 158
+ ED+G Y C+A+N+ + PS++ + A ++V + E V++
Sbjct: 665 GVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGE-------EAVLV 717
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNMEYRINKPRAEDSGEYHC 218
++ +P W + G+E+ + +S+ + RI + D+G Y C
Sbjct: 718 CEASGVPPPRVI-------------WYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTC 764
Score = 29.3 bits (64), Expect = 6.5
Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 17/144 (11%)
Query: 196 KNASNMEYRINKPRAEDSGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQD 254
+ + N + I + + G Y C +A A I V P + + G+
Sbjct: 473 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGET 532
Query: 255 ATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----ED 310
A + C+ +G + W + +P ++GR +L ++L+I+ D
Sbjct: 533 AVLSCRVLGEAPYNLTWVRDWRVLPA----STGRV--------AQLADLSLEISGIIPTD 580
Query: 311 PGEYECNATNAIGSASVVTVLRVR 334
G Y+C A+NA G L VR
Sbjct: 581 GGRYQCVASNANGVTRASVWLLVR 604
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 62.8 bits (151), Expect = 5e-10
Identities = 67/287 (23%), Positives = 107/287 (37%), Gaps = 36/287 (12%)
Query: 45 GDAFELYCDVVGSPTPEIQWWY--AEVNRAESFRQLWDGARKRRVTVNTAYGSNGVSVLR 102
G+ E+ C V SP P + W Y EV R +N + +L
Sbjct: 129 GEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNR-------------FAMLANNNLQILN 175
Query: 103 ITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSP 162
I + D G Y C + R ++ I + IS+ QK T+E
Sbjct: 176 INK---SDEGIYRCEGRVE-ARGEIDFRDIIVIVNVPPAISMPQKSFNATAER------- 224
Query: 163 VLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRK---NASNMEYRINKPRAEDSGEYHC- 218
+T C + S W +NG + K SN E + D G Y C
Sbjct: 225 GEEMTFSCRASGSPEPAI--SWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCR 282
Query: 219 VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIWRKKENGM 278
+ + A ++V P I K GQ T+ C + G P P+ W++ +G
Sbjct: 283 ATNKAGEDEKQAFLQVFVQPHIIQLKNETTYENGQ-VTLVCDAEGEPIPEITWKRAVDGF 341
Query: 279 PMDIVNTS--GRFFIINKENYTELNIVNLQITEDPGEYECNATNAIG 323
+ S GR + + + L+I +++++ D G Y+C A + IG
Sbjct: 342 TFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLS-DSGRYDCEAASRIG 387
Score = 50.1 bits (118), Expect = 4e-06
Identities = 79/341 (23%), Positives = 141/341 (41%), Gaps = 55/341 (16%)
Query: 4 SSLPSALALSLLLVSGSLLPGPGAAQNAGFVKSPMSETKLT-GDAFELYCDVVGSPTPEI 62
S L S L LL+ SG L V +S+ +L+ G++ C +G P I
Sbjct: 2 SLLLSFYLLGLLVSSGQALLQ---------VTISLSKVELSVGESKFFTCTAIGEPE-SI 51
Query: 63 QWWYAEVNRAESFRQLW---DGARKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRAS 119
W+ + + S +++ +G R R T Y +N +ED+G Y C+A+
Sbjct: 52 DWYNPQGEKIISTQRVVVQKEGVRSRL----TIYNAN-----------IEDAGIYRCQAT 96
Query: 120 NDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDSPVLPVTLQCNLTSS-SHT 178
+ + ++ + I + T + P+ E D+ V+ C ++SS +
Sbjct: 97 D--AKGQTQEATVVLEIYQKLTFREVVSPQEFKQGE----DAEVV-----CRVSSSPAPA 145
Query: 179 LTYSYWTKNGVELSATR-KNASNMEYRINKPRAEDSGEYHCVYHFVSAPKAN---ATIEV 234
+++ Y + +S R +N +I D G Y C + + + + V
Sbjct: 146 VSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIV 205
Query: 235 KAAPDITGHKRSENKN--EGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFII 292
P I+ ++S N G++ T C++ G P P W + NG ++ + ++ +
Sbjct: 206 NVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFR--NGK---LIEENEKYIL- 259
Query: 293 NKENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRV 333
K + TEL + N+ I D G Y C ATN G L+V
Sbjct: 260 -KGSNTELTVRNI-INSDGGPYVCRATNKAGEDEKQAFLQV 298
Score = 44.7 bits (104), Expect = 1e-04
Identities = 65/301 (21%), Positives = 108/301 (35%), Gaps = 63/301 (20%)
Query: 45 GDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAY---GSNGVSVL 101
G+ C GSP P I W+ + + N Y GSN + L
Sbjct: 225 GEEMTFSCRASGSPEPAISWF----------------RNGKLIEENEKYILKGSN--TEL 266
Query: 102 RITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVIIRDS 161
+ + D G Y CRA+N ++ QA + V +P I+ + ++
Sbjct: 267 TVRNIINSDGGPYVCRATNKAGEDE-----------KQAFLQVFVQPHIIQLKNETTYEN 315
Query: 162 PVLPVTLQCNLTS------------SSHTLTYSYWTKNG-VELSATRKNASNMEYRINKP 208
VTL C+ T T + +G +E+ ++S I
Sbjct: 316 G--QVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSS---LHIKDV 370
Query: 209 RAEDSGEYHC-VYHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHP 267
+ DSG Y C + + + ++++ AP ++ EG + C P
Sbjct: 371 KLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPA 430
Query: 268 DWIWRKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQIT----EDPGEYECNATNAIG 323
WR+ + +P NT+ N + Y+ + L+I D G Y C ATN IG
Sbjct: 431 SIHWRRDKLVLPAK--NTT------NLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Query: 324 S 324
+
Sbjct: 483 T 483
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/189 (23%), Positives = 72/189 (38%), Gaps = 31/189 (16%)
Query: 39 SETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTAYGSNGV 98
+ET L CD G P PEI W RA +G + + G +G
Sbjct: 309 NETTYENGQVTLVCDAEGEPIPEITW-----KRAVDGFTFTEGDKSLDGRIEVK-GQHGS 362
Query: 99 SVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVII 158
S L I + L DSG Y+C A++ I + + + P+ + S + I
Sbjct: 363 SSLHIKDVKLSDSGRYDCEAAS-----------RIGGHQKSMYLDIEYAPKFI-SNQTIY 410
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKNASNME---------YRINKPR 209
P+ + C++ S+ +W ++ + L A KN +N++ I
Sbjct: 411 YSWEGNPINISCDVKSNPPASI--HWRRDKLVLPA--KNTTNLKTYSTGRKMILEIAPTS 466
Query: 210 AEDSGEYHC 218
D G Y+C
Sbjct: 467 DNDFGRYNC 475
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 60.5 bits (145), Expect = 3e-09
Identities = 64/286 (22%), Positives = 122/286 (42%), Gaps = 37/286 (12%)
Query: 99 SVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVTSEEVII 158
++L + ++T G Y+C +N S +A+ T++VL T ++ I
Sbjct: 560 TILHLRQVTFGHEGRYQCVITN--------HFGSTYSHKARLTVNVLPS-FTKTPHDITI 610
Query: 159 RDSPVLPVTLQCNLTSSSHTLTYSYWTKNG-VELSATRKNASNME-----YRINKPRAED 212
R + + L+C T H W K+G + A R+ ++ + I + +D
Sbjct: 611 RTTTM--ARLECAATG--HPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDD 666
Query: 213 SGEYHCV-YHFVSAPKANATIEVKAAPDITGHKRSENKNEGQDATMYCKSVGYPHPDWIW 271
+G Y C + + ANAT+ V P + + G+ + CK+ G P P W
Sbjct: 667 AGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITW 726
Query: 272 RKKENGMPMDIVNTSGRFFIINKENYTELNIVNLQITEDPGEYECNATNAIGS------A 325
K + P+ + + +N +L +V + ED G Y C +N +G+
Sbjct: 727 FKGDR--PLSLTERHH----LTPDN--QLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQL 778
Query: 326 SVVTVLRVRSHLAPLWPF-LGILAEIII--LVVIIVVYEKRKRPDE 368
SV+ R + F + +++ I++ LV + ++Y+ RK+ +E
Sbjct: 779 SVLPAAGCRKDGTTVGIFTIAVVSSIVLTSLVWVCIIYQTRKKSEE 824
Score = 52.0 bits (123), Expect = 9e-07
Identities = 55/190 (28%), Positives = 77/190 (40%), Gaps = 31/190 (16%)
Query: 33 FVKSPMSETKLTGDAFELYCDVVGSPTPEIQWWYAEVNRAESFRQLWDGARKRRVTVNTA 92
F K+P T T L C G P P+I W + + F AR+RR+ V
Sbjct: 601 FTKTPHDITIRTTTMARLECAATGHPNPQIAW---QKDGGTDF----PAARERRMHV--- 650
Query: 93 YGSNGVSVLRITRLTLEDSGTYECRASNDPKRNDLRQNPSITWIRAQATISVLQKPRIVT 152
V IT + ++D+G Y C A N S I A AT++VL+ P +V
Sbjct: 651 --MPDDDVFFITDVKIDDAGVYSCTAQN-----------SAGSISANATLTVLETPSLVV 697
Query: 153 S-EEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSATRKN---ASNMEYRINKP 208
E+ ++ S V LQC T + W K LS T ++ N +
Sbjct: 698 PLEDRVV--SVGETVALQCKATGNPPPRI--TWFKGDRPLSLTERHHLTPDNQLLVVQNV 753
Query: 209 RAEDSGEYHC 218
AED+G Y C
Sbjct: 754 VAEDAGRYTC 763
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,474,468
Number of Sequences: 37866
Number of extensions: 694760
Number of successful extensions: 5107
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 251
Number of HSP's that attempted gapping in prelim test: 2021
Number of HSP's gapped (non-prelim): 1908
length of query: 394
length of database: 18,247,518
effective HSP length: 104
effective length of query: 290
effective length of database: 14,309,454
effective search space: 4149741660
effective search space used: 4149741660
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.