BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|237820622 pleckstrin homology domain containing, family N member 1 isoform a [Homo sapiens] (611 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|237820622 pleckstrin homology domain containing, family N mem... 1251 0.0 gi|237820624 pleckstrin homology domain containing, family N mem... 1129 0.0 gi|166064038 PAK-interacting exchange factor beta isoform a [Hom... 68 3e-11 gi|166064036 PAK-interacting exchange factor beta isoform d [Hom... 68 3e-11 gi|166064034 PAK-interacting exchange factor beta isoform c [Hom... 68 3e-11 gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 68 3e-11 gi|4505573 PAK-interacting exchange factor beta isoform a [Homo ... 68 3e-11 gi|169168458 PREDICTED: hypothetical protein [Homo sapiens] 49 1e-05 gi|42821110 hypothetical protein LOC340602 [Homo sapiens] 47 4e-05 gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 47 4e-05 gi|28559039 mediator complex subunit 1 [Homo sapiens] 45 1e-04 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 44 4e-04 gi|157311635 FAM83H [Homo sapiens] 43 7e-04 gi|163965366 nascent polypeptide-associated complex alpha subuni... 43 0.001 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 42 0.001 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 42 0.002 gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 41 0.003 gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 41 0.003 gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 41 0.003 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 40 0.005 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 40 0.005 gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c... 40 0.008 gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca... 40 0.008 gi|150170729 microtubule associated serine/threonine kinase 3 [H... 40 0.008 gi|33636717 hypothetical protein LOC80256 [Homo sapiens] 40 0.008 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 39 0.011 gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 39 0.011 gi|38176151 Lunapark [Homo sapiens] 39 0.011 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 39 0.011 gi|153266778 arg tyrosine kinase isoform c [Homo sapiens] 39 0.014 >gi|237820622 pleckstrin homology domain containing, family N member 1 isoform a [Homo sapiens] Length = 611 Score = 1251 bits (3237), Expect = 0.0 Identities = 611/611 (100%), Positives = 611/611 (100%) Query: 1 MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60 MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG Sbjct: 1 MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60 Query: 61 TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120 TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF Sbjct: 61 TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120 Query: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR Sbjct: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180 Query: 181 WLYHLEKQTALLGGPRRCHSAPPQRRLTRLRTASGHEPGGSAVCASRVKLQHLPAQEQWD 240 WLYHLEKQTALLGGPRRCHSAPPQRRLTRLRTASGHEPGGSAVCASRVKLQHLPAQEQWD Sbjct: 181 WLYHLEKQTALLGGPRRCHSAPPQRRLTRLRTASGHEPGGSAVCASRVKLQHLPAQEQWD 240 Query: 241 RLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIEGPLINTIRVVCA 300 RLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIEGPLINTIRVVCA Sbjct: 241 RLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIEGPLINTIRVVCA 300 Query: 301 SYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPS 360 SYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPS Sbjct: 301 SYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPS 360 Query: 361 TRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRG 420 TRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRG Sbjct: 361 TRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRG 420 Query: 421 PVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFL 480 PVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFL Sbjct: 421 PVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFL 480 Query: 481 SAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKD 540 SAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKD Sbjct: 481 SAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKD 540 Query: 541 GGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSSHQKCPQLGG 600 GGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSSHQKCPQLGG Sbjct: 541 GGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSSHQKCPQLGG 600 Query: 601 PEASGGLVQWI 611 PEASGGLVQWI Sbjct: 601 PEASGGLVQWI 611 >gi|237820624 pleckstrin homology domain containing, family N member 1 isoform b [Homo sapiens] Length = 576 Score = 1129 bits (2920), Expect = 0.0 Identities = 564/623 (90%), Positives = 564/623 (90%), Gaps = 59/623 (9%) Query: 1 MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60 MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG Sbjct: 1 MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60 Query: 61 TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120 TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF Sbjct: 61 TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120 Query: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR Sbjct: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180 Query: 181 WLYHLEKQTALLGGPRRCHSAPP------------QRRLTRLRTASGHEPGGSAVCASRV 228 WLYHLEKQTALLGGPRRCHSAPP QRRLTRLRTASGHEPGGSAVCASRV Sbjct: 181 WLYHLEKQTALLGGPRRCHSAPPQGSCGDELPWTLQRRLTRLRTASGHEPGGSAVCASRV 240 Query: 229 KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE 288 KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE Sbjct: 241 KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE 300 Query: 289 GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ 348 GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ Sbjct: 301 GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ 360 Query: 349 TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSR 408 TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTP Sbjct: 361 TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTP------------------------ 396 Query: 409 SPGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR 468 LHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR Sbjct: 397 -----------------------LHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR 433 Query: 469 RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS 528 RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS Sbjct: 434 RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS 493 Query: 529 RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETL 588 RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETL Sbjct: 494 RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETL 553 Query: 589 SSSHQKCPQLGGPEASGGLVQWI 611 SSSHQKCPQLGGPEASGGLVQWI Sbjct: 554 SSSHQKCPQLGGPEASGGLVQWI 576 >gi|166064038 PAK-interacting exchange factor beta isoform a [Homo sapiens] Length = 646 Score = 67.8 bits (164), Expect = 3e-11 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%) Query: 69 QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128 +R+ LE L+ + ++ LG V + ++V ++ S++ ++ YL LFP L + Sbjct: 275 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 334 Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184 G +QG LP T +++ LE S H AF+I+G + +LV C ++ +L W+ H Sbjct: 335 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 394 Query: 185 LEKQTAL--LGGPR-RCHSAP 202 L+KQT + +G P + HS P Sbjct: 395 LQKQTKVTSVGNPTIKPHSVP 415 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%) Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276 G+ S+V +Q ++E+ +R L+L+P L + S + G ++G+LP + I LE Sbjct: 300 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 359 Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVT 316 + E +F I G +I I V C + +D W+ L+ T Sbjct: 360 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT 399 >gi|166064036 PAK-interacting exchange factor beta isoform d [Homo sapiens] Length = 753 Score = 67.8 bits (164), Expect = 3e-11 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%) Query: 69 QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128 +R+ LE L+ + ++ LG V + ++V ++ S++ ++ YL LFP L + Sbjct: 403 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 462 Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184 G +QG LP T +++ LE S H AF+I+G + +LV C ++ +L W+ H Sbjct: 463 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 522 Query: 185 LEKQTAL--LGGPR-RCHSAP 202 L+KQT + +G P + HS P Sbjct: 523 LQKQTKVTSVGNPTIKPHSVP 543 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%) Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276 G+ S+V +Q ++E+ +R L+L+P L + S + G ++G+LP + I LE Sbjct: 428 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 487 Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVT 316 + E +F I G +I I V C + +D W+ L+ T Sbjct: 488 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT 527 >gi|166064034 PAK-interacting exchange factor beta isoform c [Homo sapiens] Length = 803 Score = 67.8 bits (164), Expect = 3e-11 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%) Query: 69 QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128 +R+ LE L+ + ++ LG V + ++V ++ S++ ++ YL LFP L + Sbjct: 453 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 512 Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184 G +QG LP T +++ LE S H AF+I+G + +LV C ++ +L W+ H Sbjct: 513 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 572 Query: 185 LEKQTAL--LGGPR-RCHSAP 202 L+KQT + +G P + HS P Sbjct: 573 LQKQTKVTSVGNPTIKPHSVP 593 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%) Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276 G+ S+V +Q ++E+ +R L+L+P L + S + G ++G+LP + I LE Sbjct: 478 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 537 Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVT 316 + E +F I G +I I V C + +D W+ L+ T Sbjct: 538 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT 577 >gi|22027528 PAK-interacting exchange factor beta isoform b [Homo sapiens] Length = 782 Score = 67.8 bits (164), Expect = 3e-11 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%) Query: 69 QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128 +R+ LE L+ + ++ LG V + ++V ++ S++ ++ YL LFP L + Sbjct: 432 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 491 Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184 G +QG LP T +++ LE S H AF+I+G + +LV C ++ +L W+ H Sbjct: 492 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 551 Query: 185 LEKQTAL--LGGPR-RCHSAP 202 L+KQT + +G P + HS P Sbjct: 552 LQKQTKVTSVGNPTIKPHSVP 572 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%) Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276 G+ S+V +Q ++E+ +R L+L+P L + S + G ++G+LP + I LE Sbjct: 457 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 516 Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVT 316 + E +F I G +I I V C + +D W+ L+ T Sbjct: 517 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT 556 >gi|4505573 PAK-interacting exchange factor beta isoform a [Homo sapiens] Length = 646 Score = 67.8 bits (164), Expect = 3e-11 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%) Query: 69 QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128 +R+ LE L+ + ++ LG V + ++V ++ S++ ++ YL LFP L + Sbjct: 275 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 334 Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184 G +QG LP T +++ LE S H AF+I+G + +LV C ++ +L W+ H Sbjct: 335 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 394 Query: 185 LEKQTAL--LGGPR-RCHSAP 202 L+KQT + +G P + HS P Sbjct: 395 LQKQTKVTSVGNPTIKPHSVP 415 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%) Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276 G+ S+V +Q ++E+ +R L+L+P L + S + G ++G+LP + I LE Sbjct: 300 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 359 Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVT 316 + E +F I G +I I V C + +D W+ L+ T Sbjct: 360 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT 399 >gi|169168458 PREDICTED: hypothetical protein [Homo sapiens] Length = 353 Score = 48.9 bits (115), Expect = 1e-05 Identities = 55/205 (26%), Positives = 77/205 (37%), Gaps = 27/205 (13%) Query: 427 LDLTQLHRLSLESSPDAPDHTSETSHSPLYADP---YTPPATSHRRVTDVRGLEEFLSAM 483 L+ +++ LE + H P P Y P + R RG S Sbjct: 102 LENLEVYTFLLEKRLKKLSREGSSHHLPRQVRPGPVYKPAPARNHRPRGGRGKASPTSFH 161 Query: 484 QSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQR---HRGSAKD 540 S R P +PL S+P SVP + S S P LS A + + HR A Sbjct: 162 VSPRAPP--APLASMPSSVPKTSIESLGS----PSSLSSSQASEPLCPLKHPSHRPPAST 215 Query: 541 GGPQPPDAPQ----LVSSAREGSPEPWLPL------TDGRSPRRSRDPGYDHLWDETLSS 590 P P + + L S + PEP PL GRSP R R+PG+ W +++ + Sbjct: 216 LSPNPTSSTESLGYLSSLSSSQPPEPLRPLKHPSHKPHGRSPPRRRNPGWVS-WSDSMQA 274 Query: 591 SHQK----CPQLGGPEASGGLVQWI 611 + CP PE S W+ Sbjct: 275 DSETDAIICPMCKAPERSCPHTWWV 299 >gi|42821110 hypothetical protein LOC340602 [Homo sapiens] Length = 503 Score = 47.4 bits (111), Expect = 4e-05 Identities = 83/293 (28%), Positives = 107/293 (36%), Gaps = 51/293 (17%) Query: 358 PPSTRT-SHSLPESSV---PSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSR----S 409 PP R LP SS PS+ CS T QA ++ +E R + SR + Sbjct: 162 PPGRRLFPEPLPPSSPGFRPSSYPCSGASTSSQATQPGPALLSHASEARPATRSRITLVA 221 Query: 410 PGSKARAEGRGPVT--------------PLHLDLTQLHRLSLESSPDAPDHTSETSHSPL 455 + RA G GPV HLD RLS ES+P + P Sbjct: 222 SALRRRASGPGPVIRGCTAQPGPAFPHRATHLDPA---RLSPESAPGPARRGRASVPGPA 278 Query: 456 Y--ADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDP--RSCS 511 D PA R V SA SAR S+P P++ V SD RS S Sbjct: 279 RRGCDSAPGPARRGRDSAPVSAPRGRDSAPGSARRGRDSAPGPALRVRTARSDAGHRSTS 338 Query: 512 SGPAGPYLLSKKGALQSRAAQRH--RGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDG 569 + P G L S+ +S R GSA + + +L +R GSP+P +P Sbjct: 339 TTP-GTGLRSRSTQQRSALLSRRSLSGSADENPSCGTGSERLAFQSRSGSPDPEVP--SR 395 Query: 570 RSP-------RRSRDPG--------YDHLWDETLSSSHQKCPQLGGPEASGGL 607 SP R+ P WDE+ SSS+ P S GL Sbjct: 396 ASPPVWHAVRMRASSPSPPGRFFLPIPQQWDESSSSSY--ASNSSSPSRSPGL 446 >gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo sapiens] Length = 776 Score = 47.4 bits (111), Expect = 4e-05 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 7/136 (5%) Query: 69 QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128 +R+ LE LS + ++NLG V+ ++V +++ ++ + YL LF L + Sbjct: 423 KRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLS 482 Query: 129 HGSE--GLTFQGLLPLTELSVCPLEG--SREHAFQITGPLPAPLLVLCPSRAELDRWLYH 184 G +QG +P+ V L+ + F+ITG ++V C + + WL Sbjct: 483 ASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQ 542 Query: 185 LEKQTALLGGPRRCHS 200 L + L+ GP C S Sbjct: 543 LNR---LIRGPASCSS 555 Score = 46.2 bits (108), Expect = 9e-05 Identities = 49/200 (24%), Positives = 84/200 (42%), Gaps = 22/200 (11%) Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276 G+ + S+V +Q+ +E+ +R L+L+ L + S + G ++G++P+ + L+ Sbjct: 448 GNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLD 507 Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVM 336 E E +F I G + I V C + +D+ WL L + P + S Sbjct: 508 EIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIR----GPASCSSLSKTSSSS 563 Query: 337 GSGRGSLSSGGQ-----------TSWDSGCLAP-PSTRTSHSLPESSVPSTVGCSSQHTP 384 S S SS GQ W CL P P R S +L S + S +P Sbjct: 564 CSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSP 623 Query: 385 DQANSDRASIGRRRTELRRS 404 + + + +R+TE + S Sbjct: 624 ---KTMKKFLHKRKTERKPS 640 >gi|28559039 mediator complex subunit 1 [Homo sapiens] Length = 1581 Score = 45.4 bits (106), Expect = 1e-04 Identities = 59/238 (24%), Positives = 91/238 (38%), Gaps = 24/238 (10%) Query: 331 PGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSD 390 P S + GS+SS G S S + S+ ++ +SS + G SS S Sbjct: 1077 PSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSS--KSEGSSSSKLSSSMYSS 1134 Query: 391 RASIGRRRTELRRSGSSRSPGS---------------KARAEGRGPVTPLHLDLTQLHRL 435 + S G +++ S S PGS K + +G+ P L L + Sbjct: 1135 QGSSGSSQSK-NSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGK----PSSLMNPSLSKP 1189 Query: 436 SLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPL 495 ++ S P S+ SP+ P TPP++ + +S S+ G SS L Sbjct: 1190 NISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGL 1249 Query: 496 PSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVS 553 S S+ P S +S A S G+ S + +H GS+K P P L + Sbjct: 1250 GS-SGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQH-GSSKGKSPSRNKKPSLTA 1305 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 43.9 bits (102), Expect = 4e-04 Identities = 59/234 (25%), Positives = 83/234 (35%), Gaps = 59/234 (25%) Query: 410 PGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYA---DPYTPPATS 466 P + +R GR P+TP R E++ P+ TS + +P A P P + Sbjct: 462 PATCSRKRGRPPLTP-------SQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVA 514 Query: 467 HRRVTDVRGLEEFLSAMQSARGP------------------------------TPSSPLP 496 + T ++ + +F+ + SAR T S P+P Sbjct: 515 PKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVP 574 Query: 497 SVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAR 556 P VP+ P + P+ P L +K R S P PP AP + Sbjct: 575 QEPAPVPS--PPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAP- 631 Query: 557 EGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSSHQKC-------PQLGGPEA 603 SP P P T R P R P + T S +H K P LG PEA Sbjct: 632 --SPPP-APATSSRRPLLLRAPQF------TPSEAHLKIYESVLTPPPLGAPEA 676 Score = 30.4 bits (67), Expect = 5.0 Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 10/135 (7%) Query: 410 PGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTP--PATSH 467 P + AR G + LT+L R + +P AP + +P + P PA Sbjct: 174 PKTPARKRGEEGTERMVQALTELLRRA--QAPQAPRSRACEPSTPRRSRGRPPGRPAGPC 231 Query: 468 RRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQ 527 RR + + A + P P P P VPV + C GP ++G Sbjct: 232 RRKQ-----QAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWK-CKEGPGPGPGTPRRGGQS 285 Query: 528 SRAAQRHRGSAKDGG 542 SR + RG + GG Sbjct: 286 SRGGRGGRGRGRGGG 300 >gi|157311635 FAM83H [Homo sapiens] Length = 1179 Score = 43.1 bits (100), Expect = 7e-04 Identities = 59/208 (28%), Positives = 89/208 (42%), Gaps = 45/208 (21%) Query: 401 LRRSGSSRSPGSKARAEG-----RGPVTPLHLDLTQLHRLSLESSPDAPDHT-SETSHSP 454 L RSGS R P A+ +G +PL L+ + H++ S +P E SP Sbjct: 823 LGRSGSDRLPSRFLSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSP 882 Query: 455 LYADPYTPPATSHRRVTDVRGLEEFLSAMQSA----RG----PTP---SSPLPSVP---- 499 P S RR + G E + SA RG P P SSP+P VP Sbjct: 883 T-------PGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPVPERRSSPVPPVPERRG 935 Query: 500 ---VSVPASDPRS--CSSGPAGPYLLSKKGALQSRAAQRHRGSAK---DGG-PQP----- 545 +++ P++ GP+GP + +KG+L+ R +G + +GG P P Sbjct: 936 SLTLTISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQ 995 Query: 546 PDAPQLVSSAREGSPEPWLPLTDGRSPR 573 P++P+ +S + S E T+ R PR Sbjct: 996 PESPRRLSLGQGDSTE---AATEERGPR 1020 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 42.7 bits (99), Expect = 0.001 Identities = 62/261 (23%), Positives = 97/261 (37%), Gaps = 20/261 (7%) Query: 319 EGAPPLPGAE--SFPGSQVMGSGRGSLSSGGQTSWD-SGCLAPPSTRTSHSLPESSVPST 375 +GAP P A S G S +G+ ++ T G LA PS + + + P ++ PS Sbjct: 1169 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228 Query: 376 VGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRL 435 G + +P A + A+ T G +P K P P + L Sbjct: 1229 KGGLATPSPKGAPTTPAA-----TPPSPKGGPATPPPKG-----APTPPAATPPSLKGGL 1278 Query: 436 SLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARG-PTPSSP 494 + AP+ T SP +PP + + +G PTP + Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAV 1338 Query: 495 LPSVP---VSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQL 551 P P ++PA+ P S GP P SK+G A H+G P P P + Sbjct: 1339 TPPSPKGTPTLPATTP-SSKGGPTTP--SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395 Query: 552 VSSAREGSPEPWLPLTDGRSP 572 S + + +PL+ ++P Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAP 1416 Score = 37.0 bits (84), Expect = 0.053 Identities = 57/237 (24%), Positives = 84/237 (35%), Gaps = 35/237 (14%) Query: 318 REGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVG 377 +EG P P + P + S S T G A PS + + + P ++ PS G Sbjct: 897 KEG-PATPAPKQAPALSMTSS---SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952 Query: 378 CSSQHTPDQANSDRASI-----GRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQL 432 + +P A + A+ G T + G+ P + + GP TP Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGPATPSPK-GAPTPPAATPPSPKGGPATP-------- 1003 Query: 433 HRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPS 492 S + +P P T + A P+ A++ T S +G + Sbjct: 1004 ---SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP-----------PSPKGSPAA 1049 Query: 493 SPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAP 549 +PLP + PA+ S GPA P S KGA AA P P AP Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPATP---SLKGAPTPPAATPPSPKGGPATPSPKGAP 1103 Score = 35.4 bits (80), Expect = 0.15 Identities = 61/249 (24%), Positives = 80/249 (32%), Gaps = 64/249 (25%) Query: 358 PPSTRTSHSLPESSVPSTVGCSSQHTP--DQANSDRASIGRRRTELRRS----GSSRSPG 411 PP T+ + +S + V S + P D S AS T L S G S SP Sbjct: 745 PPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804 Query: 412 SKARAEGRG-------------PVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYAD 458 +K +G PV+P+ + LS + S D+P T+HSP Sbjct: 805 TKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP----ATTHSPTPPS 860 Query: 459 PYTPPATSHRRVTDVRG---------------------------------LEEFLSAMQS 485 P P S +G L S+ + Sbjct: 861 PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920 Query: 486 ARGPT-----PSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKD 540 AR P+SP P + PA+ P S GPA P S K A AA Sbjct: 921 ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP---SPKWAPTPPAATPPSPKGGP 977 Query: 541 GGPQPPDAP 549 P P AP Sbjct: 978 ATPSPKGAP 986 Score = 32.7 bits (73), Expect = 1.0 Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 57/281 (20%) Query: 319 EGAPPLPGA--ESFPGSQVMGSGRGSLSSGGQTSWDSG-CLAPPSTRTSHSLPESSVPST 375 +G P LP S G S G S G + PPS + ++P T Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403 Query: 376 VGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRL 435 +P +A + T + R G A +G +TP + L + Sbjct: 1404 SPAVIPLSPKKAPA---------TPVTREG--------AATPSKGDLTPPAVTPVSLKKA 1446 Query: 436 SLESSPDAPDHTSETSHSPLYA-----DPYTPPATSHRRVTDVRGLEEFLSAMQSARGPT 490 S+P T + P P PPA A S+ Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ-------------VATSSSPKKA 1493 Query: 491 PSSPLPSVPVSVPASDPRSCSSGPAGP-----------YLLSK--------KGALQSRAA 531 P++P P ++PA P S PA P LLSK K AL A Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553 Query: 532 QRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSP 572 P P +AP SS SP P T +P Sbjct: 1554 TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP 1594 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 42.4 bits (98), Expect = 0.001 Identities = 60/222 (27%), Positives = 81/222 (36%), Gaps = 23/222 (10%) Query: 357 APPSTRTSHSLPESSVPSTVGCSSQHTPDQANS-DRASIGRRRTELRRSGSSRSPGSKAR 415 AP + +S LP SS+P S DQ +S ++ S + L ++G S PG+ Sbjct: 1323 APEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPA 1382 Query: 416 --AEGRGPVTPLHLDLTQ----------LHRLSLESSPDAPDH-TSETSHSPLYADPYTP 462 A PVT L D S P P TSE S A+ + Sbjct: 1383 PLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEA 1442 Query: 463 PATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPA----GPY 518 P V GL A ++A S+P +P P P S + PA P Sbjct: 1443 PLAVQPLVV---GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL 1499 Query: 519 LLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSP 560 L + GA+ +Q S G PP P + S EG P Sbjct: 1500 LPAAVGAVSLATSQ--LPSPPLGPTVPPQPPSALESDGEGPP 1539 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 41.6 bits (96), Expect = 0.002 Identities = 55/236 (23%), Positives = 81/236 (34%), Gaps = 34/236 (14%) Query: 389 SDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTS 448 S+ +S R R + + RS + + R P R S+ AP S Sbjct: 200 SESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPK--S 257 Query: 449 ETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPS---VPVSVPA- 504 +H AD + TS R + + R P+P+S P S P Sbjct: 258 RRAHRSTSADSASSSDTSRSRSRSAAAKTH--TTALAGRSPSPASGRRGEGDAPFSEPGT 315 Query: 505 ------SDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDG-GPQPPDAPQLVSSARE 557 S P + + P+ PY K + A + + GP+PP L++ Sbjct: 316 TSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHG 375 Query: 558 GSPEP--WLPLT-------DGRSPRRSRDPGYDHLWDETLSSSHQKCPQLGGPEAS 604 GSP+P PL+ SP R R P S +K PQ E+S Sbjct: 376 GSPQPLATTPLSQEPVNPPSEASPTRDRSP----------PKSPEKLPQSSSSESS 421 Score = 38.5 bits (88), Expect = 0.018 Identities = 70/269 (26%), Positives = 96/269 (35%), Gaps = 46/269 (17%) Query: 323 PLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQH 382 P PG P S V G S+G Q L P R S S SS S+ SS Sbjct: 2497 PAPGV---PHSDV---GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS 2550 Query: 383 TPDQANSDRASIG-------RRRTELRRSGSSRSPGSKARAEGRGP-VTPLHLDLTQLHR 434 + ++ +S + L+R S +A EGR P TP + R Sbjct: 2551 SSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTP----AKRKRR 2606 Query: 435 LSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSS- 493 S SS + +S +S S + + ++S S+ S+ P+P+ Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------SSSSSSSSPSPAKP 2654 Query: 494 -----PLPSVPVSVPASDPRSCSSGPAGPY-LLSKKGALQSRAAQRHRGSAKDGGPQPPD 547 P P+ P P + RS S P P L +L +R R S PQP Sbjct: 2655 GPQALPKPASPKKPPPGERRSRS--PRKPIDSLRDSRSLSYSPVERRRPS-----PQPSP 2707 Query: 548 APQLVSSAREGSPEPWLPLTDGRSPRRSR 576 Q SS+ GS D RSP R Sbjct: 2708 RDQQSSSSERGSRRG--QRGDSRSPSHKR 2734 Score = 37.7 bits (86), Expect = 0.031 Identities = 58/226 (25%), Positives = 80/226 (35%), Gaps = 23/226 (10%) Query: 359 PSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRS--PGSKARA 416 P+ R+ S S P+ G S TP + R+ RT RRSG SRS P + R+ Sbjct: 640 PARRSGRS--RSRTPARRGRSRSRTPARRGRSRS-----RTPARRSGRSRSRTPARRGRS 692 Query: 417 EGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGL 476 R P + + R S P + S ++ TS RR Sbjct: 693 RSRTPRRGRSRSRSLVRR--GRSHSRTPQRRGRSGSS---SERKNKSRTSQRRSRSNSSP 747 Query: 477 EEFLSAMQSARGPTPSSPLP------SVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA 530 E S + S R + SSP S+ S+ S P P S+ G+ Q +A Sbjct: 748 EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP-RRSRSGSSQPKA 806 Query: 531 AQR--HRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRR 574 R R S P P + S S P + G PR+ Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852 Score = 37.7 bits (86), Expect = 0.031 Identities = 70/274 (25%), Positives = 93/274 (33%), Gaps = 50/274 (18%) Query: 342 SLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASI-----GR 396 S S G +S + L+P + + S+ S V + TP + S AS G Sbjct: 1375 STRSSGHSSSE---LSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL 1431 Query: 397 RRTELRRSGSSRSPG---------------------------SKARAEGRGPVTPLHLDL 429 RT RRS S SPG S+ R+E P L Sbjct: 1432 PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ 1491 Query: 430 TQLHRLSLESSPDAPDH----TSETSHSPLYADPYT---PPATSHRRVTDVRGLEEFLSA 482 T R SSP+ + E S S D T P R + L+ SA Sbjct: 1492 TPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSA 1551 Query: 483 MQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGG 542 R + SSP P S P + K L R ++ GS+ + Sbjct: 1552 SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPE----VDSKSRLSPRRSR--SGSSPEVK 1605 Query: 543 PQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSR 576 +P AP+ S + SPEP P PRRSR Sbjct: 1606 DKPRAAPR-AQSGSDSSPEPKAP-APRALPRRSR 1637 Score = 36.6 bits (83), Expect = 0.069 Identities = 60/239 (25%), Positives = 84/239 (35%), Gaps = 30/239 (12%) Query: 357 APPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARA 416 AP S R S S S+ D + S S + +G S SP S R Sbjct: 254 APKSRRAHRSTSADSASSS---------DTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304 Query: 417 EGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGL 476 EG P + TQ S E++ P E T P+ S R + Sbjct: 305 EGDAPFSEPGTTSTQ-RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP 363 Query: 477 EEFLSAMQSARGPTP----SSPLPSVPVSVPA-SDPRSCSSGPAGPYLLSKKGALQS--- 528 + G +P ++PL PV+ P+ + P S P P L + + +S Sbjct: 364 PAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPP 423 Query: 529 ----RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRS-PRRSRDPGYDH 582 RH S+ + P+P AP S RE S P + RS R RD + H Sbjct: 424 SPQPTKVSRHASSSPE-SPKPAPAP---GSHREISSS---PTSKNRSHGRAKRDKSHSH 475 Score = 36.2 bits (82), Expect = 0.091 Identities = 63/268 (23%), Positives = 92/268 (34%), Gaps = 15/268 (5%) Query: 318 REGAPPLPGAESFPGSQV-MGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTV 376 ++G P P S GS + G G+ S + G P T + S P Sbjct: 1428 KDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK 1487 Query: 377 GCSSQHTPDQANSDRASIGRR--RTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHR 434 P + + + + RSGS S K A TPL Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR-----TPLGQRSRSGSS 1542 Query: 435 LSLESSPDA-PDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSS 493 L+ P A P SE+ SP P R ++ S + R + SS Sbjct: 1543 QELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS-KSRLSPRRSRSGSS 1601 Query: 494 P-LPSVPVSVPASDPRSCSSG-PAGPYLLSKKGALQSRAAQRHRGSAKDGGPQP---PDA 548 P + P + P + S SS P P + +S ++ + RG + +G P+ Sbjct: 1602 PEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH 1661 Query: 549 PQLVSSAREGSPEPWLPLTDGRSPRRSR 576 P +AR GS P T R+P R R Sbjct: 1662 PPKSRTARRGSRSSPEPKTKSRTPPRRR 1689 Score = 35.8 bits (81), Expect = 0.12 Identities = 59/222 (26%), Positives = 85/222 (38%), Gaps = 26/222 (11%) Query: 338 SGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVP--------STVGCSSQH---TPDQ 386 S R S S D AP + S S PE P S G SS+ +P+ Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651 Query: 387 ANSDRASIG---RRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRLS--LESSP 441 ++S +S + RT R S SS P +K+R R + +LT+ RLS S+ Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711 Query: 442 DAPDHTSET----SHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPS 497 +P+ S T SP + P PA R R + S RG +PS Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSP--EPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK--- 1766 Query: 498 VPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAK 539 P + S RS + G+ QS + +R R ++ Sbjct: 1767 -PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807 Score = 35.4 bits (80), Expect = 0.15 Identities = 53/210 (25%), Positives = 74/210 (35%), Gaps = 27/210 (12%) Query: 377 GCSSQHTPDQANSDRASIGRR---RTELRRSGSSRSPGSK----ARAEGRGPVTPLHLDL 429 G S TP + +S R+ RT RRS S+ SP K + R +P Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770 Query: 430 TQLH-RLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARG 488 ++L R SL S P S+T + P A S T R S + Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSR---TPPRRSRSSSSPPPKQKS 827 Query: 489 PTPS-------SPLPSVP---------VSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQ 532 TPS SP P V ++ P ++ +S + + S L+SR Sbjct: 828 KTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPS 887 Query: 533 RHRGSAKDGGPQPPDAPQLVSSAREGSPEP 562 RH S P S +R SP+P Sbjct: 888 RHSCSGSSPPRVKSSTPPRQSPSRSSSPQP 917 Score = 33.1 bits (74), Expect = 0.77 Identities = 58/230 (25%), Positives = 72/230 (31%), Gaps = 47/230 (20%) Query: 345 SGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRS 404 SG DS P S S PE +Q D + +A R RS Sbjct: 1579 SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS 1638 Query: 405 GSSRSPGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSH-SPLYADPYTPP 463 GSS ++GRGP + S ESSP+ P + S +P T Sbjct: 1639 GSS--------SKGRGP--------SPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS 1682 Query: 464 ATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKK 523 T RR + E A S R RS SS P Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRS-------------------RSASSSPE-------- 1715 Query: 524 GALQSRAAQRHRGSAKDGGPQPPDAPQLVSSARE-GSPEPWLPLTDGRSP 572 +SR RHR S P+P + + R SP GRSP Sbjct: 1716 --TRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSP 1763 Score = 32.7 bits (73), Expect = 1.0 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 5/77 (6%) Query: 370 SSVPSTVGCSSQHTPDQANSDRASI-----GRRRTELRRSGSSRSPGSKARAEGRGPVTP 424 S P+T G S TP + R+ R RT RR SR+P + R+ R P Sbjct: 564 SRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARR 623 Query: 425 LHLDLTQLHRLSLESSP 441 + + R S SP Sbjct: 624 RSRTRSPVRRRSRSRSP 640 Score = 32.3 bits (72), Expect = 1.3 Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 3/89 (3%) Query: 318 REGAPPLP---GAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPS 374 REG PP P + S S S SS +S S + S+ +S S SS PS Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650 Query: 375 TVGCSSQHTPDQANSDRASIGRRRTELRR 403 Q P A+ + G RR+ R Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPR 2679 Score = 32.0 bits (71), Expect = 1.7 Identities = 66/284 (23%), Positives = 93/284 (32%), Gaps = 34/284 (11%) Query: 318 REGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVG 377 R PP S P M S R S S L PP+ P S VPS Sbjct: 2406 RSRTPP-----SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPA----QDQPRSPVPSAFS 2456 Query: 378 ----CSSQHTPDQANSDRASIGRRRTELRRSG------SSRSPGSKARAEGRGPVT---- 423 C T A S S G T +G S +PG G P + Sbjct: 2457 DQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQ 2516 Query: 424 -PLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSA 482 P L Q + SS + +S +S S + + ++S ++ + A Sbjct: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEV-A 2575 Query: 483 MQSARGPTPSSPLPSV-----PVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGS 537 ++ PTP+ P +V P PA R SS + S + S ++ S Sbjct: 2576 LKRVPSPTPA-PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2634 Query: 538 AKDGGPQPPDAPQLVSSAREGS---PEPWLPLTDGRSPRRSRDP 578 + + S A+ G P+P P RRSR P Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP 2678 >gi|48255900 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform a [Homo sapiens] Length = 1590 Score = 41.2 bits (95), Expect = 0.003 Identities = 57/217 (26%), Positives = 73/217 (33%), Gaps = 46/217 (21%) Query: 320 GAPPLPGAESFPGSQ---VMGSGRGSLSSGGQTSWDSG-CLAPPSTRTSHSLPE--SSVP 373 GA P PG PG ++G G S G G PPS SH +P S+ Sbjct: 8 GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSV--SHPMPTMGSTDF 65 Query: 374 STVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLH 433 G H P D+ + E GS + G + G GP Sbjct: 66 PQEGMHQMHKPIDGIHDKGIV-----EDIHCGSMKGTGMRPPHPGMGP------------ 108 Query: 434 RLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSS 493 P +P HS Y P+ P G E +S+ S GPTP Sbjct: 109 -------PQSP----MDQHSQGYMSPHPSPL----------GAPEHVSSPMSGGGPTPPQ 147 Query: 494 PLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA 530 PS P ++ DP++ S GP S Q RA Sbjct: 148 MPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRA 184 >gi|48255898 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 isoform b [Homo sapiens] Length = 1572 Score = 41.2 bits (95), Expect = 0.003 Identities = 57/217 (26%), Positives = 73/217 (33%), Gaps = 46/217 (21%) Query: 320 GAPPLPGAESFPGSQ---VMGSGRGSLSSGGQTSWDSG-CLAPPSTRTSHSLPE--SSVP 373 GA P PG PG ++G G S G G PPS SH +P S+ Sbjct: 8 GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSV--SHPMPTMGSTDF 65 Query: 374 STVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLH 433 G H P D+ + E GS + G + G GP Sbjct: 66 PQEGMHQMHKPIDGIHDKGIV-----EDIHCGSMKGTGMRPPHPGMGP------------ 108 Query: 434 RLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSS 493 P +P HS Y P+ P G E +S+ S GPTP Sbjct: 109 -------PQSP----MDQHSQGYMSPHPSPL----------GAPEHVSSPMSGGGPTPPQ 147 Query: 494 PLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA 530 PS P ++ DP++ S GP S Q RA Sbjct: 148 MPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRA 184 >gi|148806908 fibronectin type III domain containing 1 [Homo sapiens] Length = 1894 Score = 41.2 bits (95), Expect = 0.003 Identities = 88/335 (26%), Positives = 120/335 (35%), Gaps = 69/335 (20%) Query: 314 AVTHREGAPPLPGAESFPGSQVMGSGR-GSLSSGGQTSWDSGCLAPPSTRTSHSLPESSV 372 A HR+ P+P G+ G+ SL+S Q S T P++ Sbjct: 917 ASLHRK--EPIPENPKSTGADTHPQGKYSSLASKAQDVQQS-----TDADTEGHSPKAQP 969 Query: 373 PSTVGCSSQHTPDQANSDR-ASIGRRRTELRR---------SGSSRSPGSKARAEGRGPV 422 ST +S P A S + S+ RR T R + S PG ++R GR P Sbjct: 970 GSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGRSPS 1029 Query: 423 TPLHLDLTQLHRLSLESSPDAPDHTSE-TSHSPLYADPYTP------PATSHRRVTDVRG 475 P L LTQ R P TS+ SHS +DPYT P + D +G Sbjct: 1030 QP-RLSLTQAGR---------PRPTSQGRSHSS--SDPYTASSRGMLPTALQNQDEDAQG 1077 Query: 476 LEEFLSA---MQSARGPTPSSPLPSVPVSVP-------------ASDPRSCSSGPAGPYL 519 + S Q R P ++ S+P D RS A P Sbjct: 1078 SYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDHRSQRGHAASPAR 1137 Query: 520 LSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPG 579 S+ G QSRA R A G +PP L S +++ + D G Sbjct: 1138 PSRPGGPQSRA--RVPSRAAPGKSEPPSKRPLSSKSQQ---------SVSAEDDEEEDAG 1186 Query: 580 -YDHLWDETLSSSHQKCPQ----LGGPEASGGLVQ 609 + ++ LSSS K P GG +A G L + Sbjct: 1187 FFKGGKEDLLSSSVPKWPSSSTPRGGKDADGSLAK 1221 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 40.4 bits (93), Expect = 0.005 Identities = 66/279 (23%), Positives = 92/279 (32%), Gaps = 53/279 (18%) Query: 312 LRAVTHREGAPPLPGAES----------FPGSQVMGSGRGSLSSGGQTSWDSGCLAPP-- 359 +++ H G+PP+PG FPG++ G GS+ +S PP Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253 Query: 360 --STRTSHSLPESSVPSTVGCSSQHT------PDQANSDRASIGRRRTELRRSGSSRSPG 411 +R P P S H P Q N R + ++ P Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313 Query: 412 SKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVT 471 S+ P + + + +L + +L S P S PL PP S R Sbjct: 314 SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPL------PPPPSERPPP 367 Query: 472 DVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSG-PAGPYLLSKKGALQSRA 530 VR P S PLP P P S S S PA P L S+ G R+ Sbjct: 368 PVRD------------PPGRSGPLPPPP---PVSRNGSTSRALPATPQLPSRSGVDSPRS 412 Query: 531 AQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDG 569 GP+PP P S+ P P + +G Sbjct: 413 -----------GPRPPLPPDRPSAGAPPPPPPSTSIRNG 440 Score = 30.4 bits (67), Expect = 5.0 Identities = 75/286 (26%), Positives = 98/286 (34%), Gaps = 43/286 (15%) Query: 312 LRAVTHREG-----APPL--PGAESF---PGSQVMGSGRGSLSSGGQTSWD---SGCLAP 358 LR+ +R+ PPL PG S P S G GR + S G S P Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170 Query: 359 PSTRTSHSLPES---SVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKAR 415 P S P+S VPST Q +P S G R+ + PG++ Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPR-PIQSSPHNRGSPPVPGGPRQPSPGPTPPP-FPGNRGT 228 Query: 416 AEGRGPV--TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDV 473 A G G + +PL +R L P P + P PP +R Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPL---PPTPSRALDDKPPP------PPPPVGNRPSIHR 279 Query: 474 RGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS-RAAQ 532 + Q+ + P PS+P PS P P GP P S G ++ R Q Sbjct: 280 EAVPP--PPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRLPQ 336 Query: 533 RHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 578 R+ + P L S R G P P R P RDP Sbjct: 337 RNLSLSS-------STPPLPSPGRSG---PLPPPPSERPPPPVRDP 372 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 40.4 bits (93), Expect = 0.005 Identities = 66/279 (23%), Positives = 92/279 (32%), Gaps = 53/279 (18%) Query: 312 LRAVTHREGAPPLPGAES----------FPGSQVMGSGRGSLSSGGQTSWDSGCLAPP-- 359 +++ H G+PP+PG FPG++ G GS+ +S PP Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253 Query: 360 --STRTSHSLPESSVPSTVGCSSQHT------PDQANSDRASIGRRRTELRRSGSSRSPG 411 +R P P S H P Q N R + ++ P Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313 Query: 412 SKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVT 471 S+ P + + + +L + +L S P S PL PP S R Sbjct: 314 SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPL------PPPPSERPPP 367 Query: 472 DVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSG-PAGPYLLSKKGALQSRA 530 VR P S PLP P P S S S PA P L S+ G R+ Sbjct: 368 PVRD------------PPGRSGPLPPPP---PVSRNGSTSRALPATPQLPSRSGVDSPRS 412 Query: 531 AQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDG 569 GP+PP P S+ P P + +G Sbjct: 413 -----------GPRPPLPPDRPSAGAPPPPPPSTSIRNG 440 Score = 30.4 bits (67), Expect = 5.0 Identities = 75/286 (26%), Positives = 98/286 (34%), Gaps = 43/286 (15%) Query: 312 LRAVTHREG-----APPL--PGAESF---PGSQVMGSGRGSLSSGGQTSWD---SGCLAP 358 LR+ +R+ PPL PG S P S G GR + S G S P Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170 Query: 359 PSTRTSHSLPES---SVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKAR 415 P S P+S VPST Q +P S G R+ + PG++ Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPR-PIQSSPHNRGSPPVPGGPRQPSPGPTPPP-FPGNRGT 228 Query: 416 AEGRGPV--TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDV 473 A G G + +PL +R L P P + P PP +R Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPL---PPTPSRALDDKPPP------PPPPVGNRPSIHR 279 Query: 474 RGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS-RAAQ 532 + Q+ + P PS+P PS P P GP P S G ++ R Q Sbjct: 280 EAVPP--PPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRLPQ 336 Query: 533 RHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 578 R+ + P L S R G P P R P RDP Sbjct: 337 RNLSLSS-------STPPLPSPGRSG---PLPPPPSERPPPPVRDP 372 >gi|209862845 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 isoform 1 [Homo sapiens] Length = 964 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/78 (39%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Query: 487 RGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA-AQRHRGSAKDGGPQP 545 RGP S L S P PAS PR S P G S G S + A RGS + G +P Sbjct: 304 RGPEDSWLLLSAPGPTPAS-PRPAS--PCGKRRYSSSGTPSSASPALSRRGSLGEEGSEP 360 Query: 546 PDAPQLVSSAREGSPEPW 563 P P L + GSP P+ Sbjct: 361 PPPPPLPLARDPGSPGPF 378 >gi|27886563 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 isoform 2 [Homo sapiens] Length = 902 Score = 39.7 bits (91), Expect = 0.008 Identities = 31/78 (39%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Query: 487 RGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA-AQRHRGSAKDGGPQP 545 RGP S L S P PAS PR S P G S G S + A RGS + G +P Sbjct: 241 RGPEDSWLLLSAPGPTPAS-PRPAS--PCGKRRYSSSGTPSSASPALSRRGSLGEEGSEP 297 Query: 546 PDAPQLVSSAREGSPEPW 563 P P L + GSP P+ Sbjct: 298 PPPPPLPLARDPGSPGPF 315 >gi|150170729 microtubule associated serine/threonine kinase 3 [Homo sapiens] Length = 1309 Score = 39.7 bits (91), Expect = 0.008 Identities = 42/138 (30%), Positives = 54/138 (39%), Gaps = 34/138 (24%) Query: 475 GLEEFLSAMQSARG-------PTPS----SPLPSVPVSVPASDPRSC--SSGPAGPYLLS 521 GL LS+ +S G P+P+ SP P VP AS P + SS PA P Sbjct: 1095 GLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSASPSSSSPASP---- 1150 Query: 522 KKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSA----------------REGSPEPWLP 565 A +R + H +AK G P+P + +S+ R SP P P Sbjct: 1151 -AAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPRSPSPLPGHP 1209 Query: 566 LTDGRSPRRSRDPGYDHL 583 RSPR R D L Sbjct: 1210 PAPARSPRLRRGQSADKL 1227 >gi|33636717 hypothetical protein LOC80256 [Homo sapiens] Length = 538 Score = 39.7 bits (91), Expect = 0.008 Identities = 60/237 (25%), Positives = 77/237 (32%), Gaps = 83/237 (35%) Query: 318 REGAPPL-PGAESFPGSQVMGSGRGSLS--------------SGGQTSWDSGCLAPPSTR 362 REG PP P G + G G G S S +SW SG +PP Sbjct: 88 REGLPPEEPSTVGLLGPEGPGLGLGVASQHFSHRGLCVVEQRSSVTSSWTSGAWSPPCP- 146 Query: 363 TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPV 422 PS C++ HT D A+ D GS + G P Sbjct: 147 ----------PSNASCNTLHTRDWASPDPGG----------------QGSLGESPGPAPP 180 Query: 423 TPLHLDLTQLHRLSL--ESSPDA---------PDHTSETS--HSPLYADPYTPPATSHRR 469 LH T LH L+ SP A P + T+ HSP +TPP Sbjct: 181 GQLHTLDTDLHSLAQIGGKSPVAGVGNGGSLWPRESPGTANGHSP----EHTPP------ 230 Query: 470 VTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGAL 526 GP P P P+ +PA + SS GP ++G+L Sbjct: 231 ------------------GPGPPGPCPTKRRLLPAGEAPDVSSEEEGPAPRRRRGSL 269 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 39.3 bits (90), Expect = 0.011 Identities = 41/158 (25%), Positives = 59/158 (37%), Gaps = 6/158 (3%) Query: 363 TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTEL-RRSGSSRSPGSKARAEGRGP 421 T+ L E S +S T A A +G T SGS+ + S AR+ G Sbjct: 1349 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 1408 Query: 422 V---TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 478 V TP L + +L SP P + ++ + Y P +P AT T G+ E Sbjct: 1409 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSE 1466 Query: 479 FLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAG 516 S S G T ++ P + S + S G Sbjct: 1467 ESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 1504 Score = 39.3 bits (90), Expect = 0.011 Identities = 41/158 (25%), Positives = 59/158 (37%), Gaps = 6/158 (3%) Query: 363 TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTEL-RRSGSSRSPGSKARAEGRGP 421 T+ L E S +S T A A +G T SGS+ + S AR+ G Sbjct: 2906 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2965 Query: 422 V---TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 478 V TP L + +L SP P + ++ + Y P +P AT T G+ E Sbjct: 2966 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSE 3023 Query: 479 FLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAG 516 S S G T ++ P + S + S G Sbjct: 3024 ESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQG 3061 Score = 38.9 bits (89), Expect = 0.014 Identities = 42/155 (27%), Positives = 61/155 (39%), Gaps = 7/155 (4%) Query: 363 TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTEL-RRSGSSRSPGSKARAEGRGP 421 T+ L E S +S T A A +G T SGS+ + S AR+ G Sbjct: 3989 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 4048 Query: 422 V---TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 478 V TP L + +L SP P + ++ + Y P +P AT T G+ E Sbjct: 4049 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSE 4106 Query: 479 FLSAMQSARGPTPSSPLP-SVPVSVPASDPRSCSS 512 S S G T ++ P S S + +P + S Sbjct: 4107 ESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHS 4141 Score = 38.5 bits (88), Expect = 0.018 Identities = 38/138 (27%), Positives = 54/138 (39%), Gaps = 6/138 (4%) Query: 363 TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTEL-RRSGSSRSPGSKARAEGRGP 421 T+ L E S +S T A A +G T SGS+ + S AR+ G Sbjct: 2432 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2491 Query: 422 V---TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 478 V TP L + +L SP P + ++ + Y P +P AT T G+ E Sbjct: 2492 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSE 2549 Query: 479 FLSAMQSARGPTPSSPLP 496 S S G T ++ P Sbjct: 2550 ESSTSHSQPGSTHTTAFP 2567 Score = 32.3 bits (72), Expect = 1.3 Identities = 60/240 (25%), Positives = 88/240 (36%), Gaps = 27/240 (11%) Query: 358 PPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAE 417 P S+ TS +S++ + +S TP A+S + G T S SPGS Sbjct: 1177 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT------SRISPGSTEITT 1230 Query: 418 GRGPVTPLHLDLTQLHRLSLESSPDAPDHT-SETSHSPL-----YADPYTPPATSHRRV- 470 G T L + SSP +P T S S + L + P ++H V Sbjct: 1231 LPGSTTTPGLSEAS---TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 1287 Query: 471 ---TDVRGL-EEFLSAMQSARGPTPSSPLP-SVPVSVPASDPRSCSSGPAGPY-LLSKKG 524 T GL EE + S+RG T ++ P S SV +P + S PA + L + Sbjct: 1288 PASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTED 1347 Query: 525 ALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGR-----SPRRSRDPG 579 + S + P +++A G P + G SP RS G Sbjct: 1348 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 1407 Score = 30.8 bits (68), Expect = 3.8 Identities = 59/240 (24%), Positives = 87/240 (36%), Gaps = 27/240 (11%) Query: 358 PPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAE 417 P S+ TS +S++ + +S TP A+S + G T S SPGS Sbjct: 2260 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT------SRISPGSTEITT 2313 Query: 418 GRGPVTPLHLDLTQLHRLSLESSPDAPDHT-SETSHSPL-----YADPYTPPATSHRRV- 470 G T L + SSP +P T S S + L + P ++H V Sbjct: 2314 LPGSTTTPGLSEAS---TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 2370 Query: 471 ---TDVRGL-EEFLSAMQSARGPTPSSPLPSVP-VSVPASDPRSCSSGPAGPY-LLSKKG 524 T GL EE + S+ G T ++ P P SV +P + S PA + L + Sbjct: 2371 PASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTED 2430 Query: 525 ALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGR-----SPRRSRDPG 579 + S + P +++A G P + G SP RS G Sbjct: 2431 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2490 Score = 29.6 bits (65), Expect = 8.5 Identities = 59/240 (24%), Positives = 87/240 (36%), Gaps = 27/240 (11%) Query: 358 PPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAE 417 P S+ TS +S++ + +S TP A+S + G T S SPGS Sbjct: 2734 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT------SRISPGSTEITT 2787 Query: 418 GRGPVTPLHLDLTQLHRLSLESSPDAPDHT-SETSHSPL-----YADPYTPPATSHRRV- 470 G T L + SSP +P T S S + L + P ++H V Sbjct: 2788 LPGSTTTPGLSEAS---TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 2844 Query: 471 ---TDVRGL-EEFLSAMQSARGPTPSSPLP-SVPVSVPASDPRSCSSGPAGPY-LLSKKG 524 T GL EE + S+ G T ++ P S SV +P + S PA + L + Sbjct: 2845 PASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTED 2904 Query: 525 ALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGR-----SPRRSRDPG 579 + S + P +++A G P + G SP RS G Sbjct: 2905 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2964 >gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo sapiens] Length = 2036 Score = 39.3 bits (90), Expect = 0.011 Identities = 41/158 (25%), Positives = 59/158 (37%), Gaps = 6/158 (3%) Query: 363 TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTEL-RRSGSSRSPGSKARAEGRGP 421 T+ L E S +S T A A +G T SGS+ + S AR+ G Sbjct: 836 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 895 Query: 422 V---TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 478 V TP L + +L SP P + ++ + Y P +P AT T G+ E Sbjct: 896 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSE 953 Query: 479 FLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAG 516 S S G T ++ P + S + S G Sbjct: 954 ESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 991 Score = 32.3 bits (72), Expect = 1.3 Identities = 60/240 (25%), Positives = 88/240 (36%), Gaps = 27/240 (11%) Query: 358 PPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAE 417 P S+ TS +S++ + +S TP A+S + G T S SPGS Sbjct: 664 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT------SRISPGSTEITT 717 Query: 418 GRGPVTPLHLDLTQLHRLSLESSPDAPDHT-SETSHSPL-----YADPYTPPATSHRRV- 470 G T L + SSP +P T S S + L + P ++H V Sbjct: 718 LPGSTTTPGLSEAS---TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 774 Query: 471 ---TDVRGL-EEFLSAMQSARGPTPSSPLP-SVPVSVPASDPRSCSSGPAGPY-LLSKKG 524 T GL EE + S+RG T ++ P S SV +P + S PA + L + Sbjct: 775 PASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTED 834 Query: 525 ALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGR-----SPRRSRDPG 579 + S + P +++A G P + G SP RS G Sbjct: 835 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 894 >gi|38176151 Lunapark [Homo sapiens] Length = 428 Score = 39.3 bits (90), Expect = 0.011 Identities = 28/74 (37%), Positives = 31/74 (41%), Gaps = 5/74 (6%) Query: 481 SAMQSARGPTPSSPLPSVPVSVPASD-PRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAK 539 +A Q PTP+SP P VP S P SS P GP + AL S RH GS Sbjct: 170 TAAQRNLSPTPASPNQGPPPQVPVSPGPPKDSSAPGGPPERTVTPALSSNVLPRHLGSPA 229 Query: 540 DGGP----QPPDAP 549 P PP P Sbjct: 230 TSVPGMGLHPPGPP 243 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 39.3 bits (90), Expect = 0.011 Identities = 67/279 (24%), Positives = 93/279 (33%), Gaps = 19/279 (6%) Query: 322 PPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQ 381 PP P PG GS R S S SG + T T + P++ G + Sbjct: 551 PPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQP 610 Query: 382 HTPDQANSDR---ASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRLSLE 438 P++ S R AS+ T L S S +P ++ G +TPL R + Sbjct: 611 PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRS---GPQILTPLG------DRFVIP 661 Query: 439 SSPDAPDHTSETSHSPLYADPYTP----PATSHRRVTDVRGLEEFLSAMQSARGPTPSSP 494 P P S P +P P PA V+ + Q+ P SP Sbjct: 662 PHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESP 721 Query: 495 LPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGG--PQPPDAPQLV 552 + S S P S P S P P + A++ +D P PP AP+ Sbjct: 722 VISKDQSPPPSPPPSYHP-PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQ 780 Query: 553 SSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSS 591 + P P SP + G L +SS Sbjct: 781 DLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASS 819 >gi|153266778 arg tyrosine kinase isoform c [Homo sapiens] Length = 1167 Score = 38.9 bits (89), Expect = 0.014 Identities = 55/223 (24%), Positives = 85/223 (38%), Gaps = 34/223 (15%) Query: 314 AVTHREGAPP---LPGAESFP-GSQVMGSGR----GSLSSGGQTSWDSGCLAPPSTRTSH 365 A+T ++ PP + G + P G + G R G G Q W S A P T+H Sbjct: 855 AITEKD--PPGVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVLPTTH 912 Query: 366 SLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPL 425 + VP + + +HTP +D IG + S G+K + VT Sbjct: 913 N---HKVPVLISPTLKHTP----ADVQLIG-----------TDSQGNKFKLLSEHQVTSS 954 Query: 426 HLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPP----ATSHRRVTDVRGLEEFLS 481 D + R+ + +P P H + +DP P A T G + L Sbjct: 955 G-DKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQEGGKKAALG 1013 Query: 482 AMQ-SARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKK 523 A+ S + P P P VP+ + P ++G AG + +K Sbjct: 1014 AVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRK 1056 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.133 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,768,890 Number of Sequences: 37866 Number of extensions: 1675066 Number of successful extensions: 9803 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 457 Number of HSP's that attempted gapping in prelim test: 8942 Number of HSP's gapped (non-prelim): 1261 length of query: 611 length of database: 18,247,518 effective HSP length: 108 effective length of query: 503 effective length of database: 14,157,990 effective search space: 7121468970 effective search space used: 7121468970 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.