Guide to the Human Genome
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Search of human proteins with 237820622

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|237820622 pleckstrin homology domain containing, family N
member 1 isoform a [Homo sapiens]
         (611 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|237820622 pleckstrin homology domain containing, family N mem...  1251   0.0  
gi|237820624 pleckstrin homology domain containing, family N mem...  1129   0.0  
gi|166064038 PAK-interacting exchange factor beta isoform a [Hom...    68   3e-11
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom...    68   3e-11
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom...    68   3e-11
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo...    68   3e-11
gi|4505573 PAK-interacting exchange factor beta isoform a [Homo ...    68   3e-11
gi|169168458 PREDICTED: hypothetical protein [Homo sapiens]            49   1e-05
gi|42821110 hypothetical protein LOC340602 [Homo sapiens]              47   4e-05
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo...    47   4e-05
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  45   1e-04
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    44   4e-04
gi|157311635 FAM83H [Homo sapiens]                                     43   7e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    43   0.001
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       42   0.001
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        42   0.002
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    41   0.003
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    41   0.003
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    41   0.003
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    40   0.005
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    40   0.005
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...    40   0.008
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...    40   0.008
gi|150170729 microtubule associated serine/threonine kinase 3 [H...    40   0.008
gi|33636717 hypothetical protein LOC80256 [Homo sapiens]               40   0.008
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        39   0.011
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    39   0.011
gi|38176151 Lunapark [Homo sapiens]                                    39   0.011
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              39   0.011
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]              39   0.014

>gi|237820622 pleckstrin homology domain containing, family N member
           1 isoform a [Homo sapiens]
          Length = 611

 Score = 1251 bits (3237), Expect = 0.0
 Identities = 611/611 (100%), Positives = 611/611 (100%)

Query: 1   MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60
           MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG
Sbjct: 1   MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60

Query: 61  TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120
           TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF
Sbjct: 61  TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120

Query: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180
           PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR
Sbjct: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180

Query: 181 WLYHLEKQTALLGGPRRCHSAPPQRRLTRLRTASGHEPGGSAVCASRVKLQHLPAQEQWD 240
           WLYHLEKQTALLGGPRRCHSAPPQRRLTRLRTASGHEPGGSAVCASRVKLQHLPAQEQWD
Sbjct: 181 WLYHLEKQTALLGGPRRCHSAPPQRRLTRLRTASGHEPGGSAVCASRVKLQHLPAQEQWD 240

Query: 241 RLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIEGPLINTIRVVCA 300
           RLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIEGPLINTIRVVCA
Sbjct: 241 RLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIEGPLINTIRVVCA 300

Query: 301 SYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPS 360
           SYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPS
Sbjct: 301 SYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPS 360

Query: 361 TRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRG 420
           TRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRG
Sbjct: 361 TRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRG 420

Query: 421 PVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFL 480
           PVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFL
Sbjct: 421 PVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFL 480

Query: 481 SAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKD 540
           SAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKD
Sbjct: 481 SAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKD 540

Query: 541 GGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSSHQKCPQLGG 600
           GGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSSHQKCPQLGG
Sbjct: 541 GGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSSHQKCPQLGG 600

Query: 601 PEASGGLVQWI 611
           PEASGGLVQWI
Sbjct: 601 PEASGGLVQWI 611


>gi|237820624 pleckstrin homology domain containing, family N member
           1 isoform b [Homo sapiens]
          Length = 576

 Score = 1129 bits (2920), Expect = 0.0
 Identities = 564/623 (90%), Positives = 564/623 (90%), Gaps = 59/623 (9%)

Query: 1   MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60
           MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG
Sbjct: 1   MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60

Query: 61  TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120
           TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF
Sbjct: 61  TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120

Query: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180
           PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR
Sbjct: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180

Query: 181 WLYHLEKQTALLGGPRRCHSAPP------------QRRLTRLRTASGHEPGGSAVCASRV 228
           WLYHLEKQTALLGGPRRCHSAPP            QRRLTRLRTASGHEPGGSAVCASRV
Sbjct: 181 WLYHLEKQTALLGGPRRCHSAPPQGSCGDELPWTLQRRLTRLRTASGHEPGGSAVCASRV 240

Query: 229 KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE 288
           KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE
Sbjct: 241 KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE 300

Query: 289 GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ 348
           GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ
Sbjct: 301 GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ 360

Query: 349 TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSR 408
           TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTP                        
Sbjct: 361 TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTP------------------------ 396

Query: 409 SPGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR 468
                                  LHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR
Sbjct: 397 -----------------------LHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR 433

Query: 469 RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS 528
           RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS
Sbjct: 434 RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS 493

Query: 529 RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETL 588
           RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETL
Sbjct: 494 RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETL 553

Query: 589 SSSHQKCPQLGGPEASGGLVQWI 611
           SSSHQKCPQLGGPEASGGLVQWI
Sbjct: 554 SSSHQKCPQLGGPEASGGLVQWI 576


>gi|166064038 PAK-interacting exchange factor beta isoform a [Homo
           sapiens]
          Length = 646

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   L+   +      ++ LG V + ++V ++   S++ ++ YL LFP  L   +
Sbjct: 275 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 334

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG LP T +++  LE S  H  AF+I+G +   +LV C ++ +L  W+ H
Sbjct: 335 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 394

Query: 185 LEKQTAL--LGGPR-RCHSAP 202
           L+KQT +  +G P  + HS P
Sbjct: 395 LQKQTKVTSVGNPTIKPHSVP 415



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276
           G+    S+V +Q   ++E+ +R L+L+P  L + S    + G  ++G+LP   + I  LE
Sbjct: 300 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 359

Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVT 316
           + E    +F I G +I  I V C + +D   W+  L+  T
Sbjct: 360 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT 399


>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
           sapiens]
          Length = 753

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   L+   +      ++ LG V + ++V ++   S++ ++ YL LFP  L   +
Sbjct: 403 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 462

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG LP T +++  LE S  H  AF+I+G +   +LV C ++ +L  W+ H
Sbjct: 463 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 522

Query: 185 LEKQTAL--LGGPR-RCHSAP 202
           L+KQT +  +G P  + HS P
Sbjct: 523 LQKQTKVTSVGNPTIKPHSVP 543



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276
           G+    S+V +Q   ++E+ +R L+L+P  L + S    + G  ++G+LP   + I  LE
Sbjct: 428 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 487

Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVT 316
           + E    +F I G +I  I V C + +D   W+  L+  T
Sbjct: 488 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT 527


>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
           sapiens]
          Length = 803

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   L+   +      ++ LG V + ++V ++   S++ ++ YL LFP  L   +
Sbjct: 453 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 512

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG LP T +++  LE S  H  AF+I+G +   +LV C ++ +L  W+ H
Sbjct: 513 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 572

Query: 185 LEKQTAL--LGGPR-RCHSAP 202
           L+KQT +  +G P  + HS P
Sbjct: 573 LQKQTKVTSVGNPTIKPHSVP 593



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276
           G+    S+V +Q   ++E+ +R L+L+P  L + S    + G  ++G+LP   + I  LE
Sbjct: 478 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 537

Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVT 316
           + E    +F I G +I  I V C + +D   W+  L+  T
Sbjct: 538 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT 577


>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
           sapiens]
          Length = 782

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   L+   +      ++ LG V + ++V ++   S++ ++ YL LFP  L   +
Sbjct: 432 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 491

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG LP T +++  LE S  H  AF+I+G +   +LV C ++ +L  W+ H
Sbjct: 492 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 551

Query: 185 LEKQTAL--LGGPR-RCHSAP 202
           L+KQT +  +G P  + HS P
Sbjct: 552 LQKQTKVTSVGNPTIKPHSVP 572



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276
           G+    S+V +Q   ++E+ +R L+L+P  L + S    + G  ++G+LP   + I  LE
Sbjct: 457 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 516

Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVT 316
           + E    +F I G +I  I V C + +D   W+  L+  T
Sbjct: 517 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT 556


>gi|4505573 PAK-interacting exchange factor beta isoform a [Homo
           sapiens]
          Length = 646

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   L+   +      ++ LG V + ++V ++   S++ ++ YL LFP  L   +
Sbjct: 275 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 334

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG LP T +++  LE S  H  AF+I+G +   +LV C ++ +L  W+ H
Sbjct: 335 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 394

Query: 185 LEKQTAL--LGGPR-RCHSAP 202
           L+KQT +  +G P  + HS P
Sbjct: 395 LQKQTKVTSVGNPTIKPHSVP 415



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 30/100 (30%), Positives = 52/100 (52%), Gaps = 3/100 (3%)

Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276
           G+    S+V +Q   ++E+ +R L+L+P  L + S    + G  ++G+LP   + I  LE
Sbjct: 300 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 359

Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVT 316
           + E    +F I G +I  I V C + +D   W+  L+  T
Sbjct: 360 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT 399


>gi|169168458 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 353

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 55/205 (26%), Positives = 77/205 (37%), Gaps = 27/205 (13%)

Query: 427 LDLTQLHRLSLESSPDAPDHTSETSHSPLYADP---YTPPATSHRRVTDVRGLEEFLSAM 483
           L+  +++   LE           + H P    P   Y P    + R    RG     S  
Sbjct: 102 LENLEVYTFLLEKRLKKLSREGSSHHLPRQVRPGPVYKPAPARNHRPRGGRGKASPTSFH 161

Query: 484 QSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQR---HRGSAKD 540
            S R P   +PL S+P SVP +   S  S    P  LS   A +     +   HR  A  
Sbjct: 162 VSPRAPP--APLASMPSSVPKTSIESLGS----PSSLSSSQASEPLCPLKHPSHRPPAST 215

Query: 541 GGPQPPDAPQ----LVSSAREGSPEPWLPL------TDGRSPRRSRDPGYDHLWDETLSS 590
             P P  + +    L S +    PEP  PL        GRSP R R+PG+   W +++ +
Sbjct: 216 LSPNPTSSTESLGYLSSLSSSQPPEPLRPLKHPSHKPHGRSPPRRRNPGWVS-WSDSMQA 274

Query: 591 SHQK----CPQLGGPEASGGLVQWI 611
             +     CP    PE S     W+
Sbjct: 275 DSETDAIICPMCKAPERSCPHTWWV 299


>gi|42821110 hypothetical protein LOC340602 [Homo sapiens]
          Length = 503

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 83/293 (28%), Positives = 107/293 (36%), Gaps = 51/293 (17%)

Query: 358 PPSTRT-SHSLPESSV---PSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSR----S 409
           PP  R     LP SS    PS+  CS   T  QA     ++    +E R +  SR    +
Sbjct: 162 PPGRRLFPEPLPPSSPGFRPSSYPCSGASTSSQATQPGPALLSHASEARPATRSRITLVA 221

Query: 410 PGSKARAEGRGPVT--------------PLHLDLTQLHRLSLESSPDAPDHTSETSHSPL 455
              + RA G GPV                 HLD     RLS ES+P        +   P 
Sbjct: 222 SALRRRASGPGPVIRGCTAQPGPAFPHRATHLDPA---RLSPESAPGPARRGRASVPGPA 278

Query: 456 Y--ADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDP--RSCS 511
               D    PA   R    V       SA  SAR    S+P P++ V    SD   RS S
Sbjct: 279 RRGCDSAPGPARRGRDSAPVSAPRGRDSAPGSARRGRDSAPGPALRVRTARSDAGHRSTS 338

Query: 512 SGPAGPYLLSKKGALQSRAAQRH--RGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDG 569
           + P G  L S+    +S    R    GSA +       + +L   +R GSP+P +P    
Sbjct: 339 TTP-GTGLRSRSTQQRSALLSRRSLSGSADENPSCGTGSERLAFQSRSGSPDPEVP--SR 395

Query: 570 RSP-------RRSRDPG--------YDHLWDETLSSSHQKCPQLGGPEASGGL 607
            SP        R+  P             WDE+ SSS+        P  S GL
Sbjct: 396 ASPPVWHAVRMRASSPSPPGRFFLPIPQQWDESSSSSY--ASNSSSPSRSPGL 446


>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
           sapiens]
          Length = 776

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 7/136 (5%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   LS   +      ++NLG V+  ++V +++   ++  + YL LF   L   +
Sbjct: 423 KRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLS 482

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEG--SREHAFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG +P+    V  L+     +  F+ITG     ++V C +  +   WL  
Sbjct: 483 ASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQ 542

Query: 185 LEKQTALLGGPRRCHS 200
           L +   L+ GP  C S
Sbjct: 543 LNR---LIRGPASCSS 555



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 49/200 (24%), Positives = 84/200 (42%), Gaps = 22/200 (11%)

Query: 220 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 276
           G+ +  S+V +Q+   +E+ +R L+L+   L + S    + G  ++G++P+    +  L+
Sbjct: 448 GNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLD 507

Query: 277 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVM 336
           E E    +F I G  +  I V C + +D+  WL  L  +       P   +     S   
Sbjct: 508 EIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIR----GPASCSSLSKTSSSS 563

Query: 337 GSGRGSLSSGGQ-----------TSWDSGCLAP-PSTRTSHSLPESSVPSTVGCSSQHTP 384
            S   S SS GQ             W   CL P P  R S +L      S +   S  +P
Sbjct: 564 CSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSP 623

Query: 385 DQANSDRASIGRRRTELRRS 404
               + +  + +R+TE + S
Sbjct: 624 ---KTMKKFLHKRKTERKPS 640


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 59/238 (24%), Positives = 91/238 (38%), Gaps = 24/238 (10%)

Query: 331  PGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSD 390
            P S    +  GS+SS G  S  S   +  S+ ++    +SS   + G SS        S 
Sbjct: 1077 PSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSS--KSEGSSSSKLSSSMYSS 1134

Query: 391  RASIGRRRTELRRSGSSRSPGS---------------KARAEGRGPVTPLHLDLTQLHRL 435
            + S G  +++   S S   PGS               K + +G+    P  L    L + 
Sbjct: 1135 QGSSGSSQSK-NSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGK----PSSLMNPSLSKP 1189

Query: 436  SLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPL 495
            ++  S   P   S+   SP+   P TPP++  +           +S   S+ G   SS L
Sbjct: 1190 NISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGL 1249

Query: 496  PSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVS 553
             S   S+    P S +S  A     S  G+  S +  +H GS+K   P     P L +
Sbjct: 1250 GS-SGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQH-GSSKGKSPSRNKKPSLTA 1305


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 59/234 (25%), Positives = 83/234 (35%), Gaps = 59/234 (25%)

Query: 410 PGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYA---DPYTPPATS 466
           P + +R  GR P+TP         R   E++   P+ TS  + +P  A    P   P  +
Sbjct: 462 PATCSRKRGRPPLTP-------SQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVA 514

Query: 467 HRRVTDVRGLEEFLSAMQSARGP------------------------------TPSSPLP 496
            +  T ++ + +F+  + SAR                                T S P+P
Sbjct: 515 PKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVP 574

Query: 497 SVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAR 556
             P  VP+  P    + P+ P  L +K     R       S     P PP AP    +  
Sbjct: 575 QEPAPVPS--PPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAP- 631

Query: 557 EGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSSHQKC-------PQLGGPEA 603
             SP P  P T  R P   R P +      T S +H K        P LG PEA
Sbjct: 632 --SPPP-APATSSRRPLLLRAPQF------TPSEAHLKIYESVLTPPPLGAPEA 676



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 35/135 (25%), Positives = 51/135 (37%), Gaps = 10/135 (7%)

Query: 410 PGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTP--PATSH 467
           P + AR  G      +   LT+L R +   +P AP   +    +P  +    P  PA   
Sbjct: 174 PKTPARKRGEEGTERMVQALTELLRRA--QAPQAPRSRACEPSTPRRSRGRPPGRPAGPC 231

Query: 468 RRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQ 527
           RR       +  + A  +   P P  P P VPV       + C  GP       ++G   
Sbjct: 232 RRKQ-----QAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWK-CKEGPGPGPGTPRRGGQS 285

Query: 528 SRAAQRHRGSAKDGG 542
           SR  +  RG  + GG
Sbjct: 286 SRGGRGGRGRGRGGG 300


>gi|157311635 FAM83H [Homo sapiens]
          Length = 1179

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 59/208 (28%), Positives = 89/208 (42%), Gaps = 45/208 (21%)

Query: 401  LRRSGSSRSPGSKARAEG-----RGPVTPLHLDLTQLHRLSLESSPDAPDHT-SETSHSP 454
            L RSGS R P     A+      +G  +PL L+ +  H++    S  +P     E   SP
Sbjct: 823  LGRSGSDRLPSRFLSAQSHSTSPQGLDSPLPLEGSGAHQVLHNESKGSPTSAYPERKGSP 882

Query: 455  LYADPYTPPATSHRRVTDVRGLEEFLSAMQSA----RG----PTP---SSPLPSVP---- 499
                    P  S RR +   G  E   +  SA    RG    P P   SSP+P VP    
Sbjct: 883  T-------PGFSTRRGSPTTGFIEQKGSPTSAYPERRGSPVPPVPERRSSPVPPVPERRG 935

Query: 500  ---VSVPASDPRS--CSSGPAGPYLLSKKGALQSRAAQRHRGSAK---DGG-PQP----- 545
               +++    P++     GP+GP  + +KG+L+ R     +G  +   +GG P P     
Sbjct: 936  SLTLTISGESPKAGPAEEGPSGPMEVLRKGSLRLRQLLSPKGERRMEDEGGFPVPQENGQ 995

Query: 546  PDAPQLVSSAREGSPEPWLPLTDGRSPR 573
            P++P+ +S  +  S E     T+ R PR
Sbjct: 996  PESPRRLSLGQGDSTE---AATEERGPR 1020


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 62/261 (23%), Positives = 97/261 (37%), Gaps = 20/261 (7%)

Query: 319  EGAPPLPGAE--SFPGSQVMGSGRGSLSSGGQTSWD-SGCLAPPSTRTSHSLPESSVPST 375
            +GAP  P A   S  G     S +G+ ++   T     G LA PS + + + P ++ PS 
Sbjct: 1169 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228

Query: 376  VGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRL 435
             G  +  +P  A +  A+     T     G   +P  K       P  P     +    L
Sbjct: 1229 KGGLATPSPKGAPTTPAA-----TPPSPKGGPATPPPKG-----APTPPAATPPSLKGGL 1278

Query: 436  SLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARG-PTPSSP 494
            +      AP+    T  SP      +PP  +           +        +G PTP + 
Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAV 1338

Query: 495  LPSVP---VSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQL 551
             P  P    ++PA+ P S   GP  P   SK+G     A   H+G      P P   P +
Sbjct: 1339 TPPSPKGTPTLPATTP-SSKGGPTTP--SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395

Query: 552  VSSAREGSPEPWLPLTDGRSP 572
             S   + +    +PL+  ++P
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAP 1416



 Score = 37.0 bits (84), Expect = 0.053
 Identities = 57/237 (24%), Positives = 84/237 (35%), Gaps = 35/237 (14%)

Query: 318  REGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVG 377
            +EG P  P  +  P   +  S   S      T    G  A PS + + + P ++ PS  G
Sbjct: 897  KEG-PATPAPKQAPALSMTSS---SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952

Query: 378  CSSQHTPDQANSDRASI-----GRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQL 432
              +  +P  A +  A+      G   T   + G+   P +   +   GP TP        
Sbjct: 953  GPATPSPKWAPTPPAATPPSPKGGPATPSPK-GAPTPPAATPPSPKGGPATP-------- 1003

Query: 433  HRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPS 492
               S + +P  P  T  +      A P+   A++    T             S +G   +
Sbjct: 1004 ---SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP-----------PSPKGSPAA 1049

Query: 493  SPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAP 549
            +PLP    + PA+   S   GPA P   S KGA    AA           P P  AP
Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPATP---SLKGAPTPPAATPPSPKGGPATPSPKGAP 1103



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 61/249 (24%), Positives = 80/249 (32%), Gaps = 64/249 (25%)

Query: 358 PPSTRTSHSLPESSVPSTVGCSSQHTP--DQANSDRASIGRRRTELRRS----GSSRSPG 411
           PP T+    +  +S  + V  S +  P  D   S  AS     T L  S    G S SP 
Sbjct: 745 PPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804

Query: 412 SKARAEGRG-------------PVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYAD 458
           +K     +G             PV+P+       + LS + S D+P     T+HSP    
Sbjct: 805 TKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP----ATTHSPTPPS 860

Query: 459 PYTPPATSHRRVTDVRG---------------------------------LEEFLSAMQS 485
           P   P  S       +G                                 L    S+ + 
Sbjct: 861 PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920

Query: 486 ARGPT-----PSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKD 540
           AR        P+SP P    + PA+ P S   GPA P   S K A    AA         
Sbjct: 921 ARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP---SPKWAPTPPAATPPSPKGGP 977

Query: 541 GGPQPPDAP 549
             P P  AP
Sbjct: 978 ATPSPKGAP 986



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 57/281 (20%)

Query: 319  EGAPPLPGA--ESFPGSQVMGSGRGSLSSGGQTSWDSG-CLAPPSTRTSHSLPESSVPST 375
            +G P LP     S  G     S  G        S   G  + PPS +   ++P      T
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403

Query: 376  VGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRL 435
                   +P +A +         T + R G        A    +G +TP  +    L + 
Sbjct: 1404 SPAVIPLSPKKAPA---------TPVTREG--------AATPSKGDLTPPAVTPVSLKKA 1446

Query: 436  SLESSPDAPDHTSETSHSPLYA-----DPYTPPATSHRRVTDVRGLEEFLSAMQSARGPT 490
               S+P     T  +   P         P  PPA                 A  S+    
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ-------------VATSSSPKKA 1493

Query: 491  PSSPLPSVPVSVPASDPRSCSSGPAGP-----------YLLSK--------KGALQSRAA 531
            P++P P    ++PA  P S    PA P            LLSK        K AL   A 
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553

Query: 532  QRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSP 572
                       P P +AP   SS    SP    P T   +P
Sbjct: 1554 TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP 1594


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 60/222 (27%), Positives = 81/222 (36%), Gaps = 23/222 (10%)

Query: 357  APPSTRTSHSLPESSVPSTVGCSSQHTPDQANS-DRASIGRRRTELRRSGSSRSPGSKAR 415
            AP +  +S  LP SS+P      S    DQ +S ++ S    +  L ++G S  PG+   
Sbjct: 1323 APEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPA 1382

Query: 416  --AEGRGPVTPLHLDLTQ----------LHRLSLESSPDAPDH-TSETSHSPLYADPYTP 462
              A    PVT L  D                 S    P  P   TSE   S   A+ +  
Sbjct: 1383 PLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEA 1442

Query: 463  PATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPA----GPY 518
            P      V    GL     A ++A     S+P   +P   P   P S +  PA     P 
Sbjct: 1443 PLAVQPLVV---GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL 1499

Query: 519  LLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSP 560
            L +  GA+    +Q    S   G   PP  P  + S  EG P
Sbjct: 1500 LPAAVGAVSLATSQ--LPSPPLGPTVPPQPPSALESDGEGPP 1539


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 55/236 (23%), Positives = 81/236 (34%), Gaps = 34/236 (14%)

Query: 389 SDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTS 448
           S+ +S  R R +  +    RS     + + R P            R    S+  AP   S
Sbjct: 200 SESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPK--S 257

Query: 449 ETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPS---VPVSVPA- 504
             +H    AD  +   TS  R           +   + R P+P+S        P S P  
Sbjct: 258 RRAHRSTSADSASSSDTSRSRSRSAAAKTH--TTALAGRSPSPASGRRGEGDAPFSEPGT 315

Query: 505 ------SDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDG-GPQPPDAPQLVSSARE 557
                 S P + +  P+ PY    K   +  A +      +   GP+PP    L++    
Sbjct: 316 TSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHG 375

Query: 558 GSPEP--WLPLT-------DGRSPRRSRDPGYDHLWDETLSSSHQKCPQLGGPEAS 604
           GSP+P    PL+          SP R R P            S +K PQ    E+S
Sbjct: 376 GSPQPLATTPLSQEPVNPPSEASPTRDRSP----------PKSPEKLPQSSSSESS 421



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 70/269 (26%), Positives = 96/269 (35%), Gaps = 46/269 (17%)

Query: 323  PLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQH 382
            P PG    P S V   G    S+G Q       L P   R S S   SS  S+   SS  
Sbjct: 2497 PAPGV---PHSDV---GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS 2550

Query: 383  TPDQANSDRASIG-------RRRTELRRSGSSRSPGSKARAEGRGP-VTPLHLDLTQLHR 434
            +   ++   +S         +    L+R  S      +A  EGR P  TP      +  R
Sbjct: 2551 SSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTP----AKRKRR 2606

Query: 435  LSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSS- 493
             S  SS  +   +S +S S   +   +  ++S              S+  S+  P+P+  
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS------------SSSSSSSSPSPAKP 2654

Query: 494  -----PLPSVPVSVPASDPRSCSSGPAGPY-LLSKKGALQSRAAQRHRGSAKDGGPQPPD 547
                 P P+ P   P  + RS S  P  P   L    +L     +R R S     PQP  
Sbjct: 2655 GPQALPKPASPKKPPPGERRSRS--PRKPIDSLRDSRSLSYSPVERRRPS-----PQPSP 2707

Query: 548  APQLVSSAREGSPEPWLPLTDGRSPRRSR 576
              Q  SS+  GS        D RSP   R
Sbjct: 2708 RDQQSSSSERGSRRG--QRGDSRSPSHKR 2734



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 58/226 (25%), Positives = 80/226 (35%), Gaps = 23/226 (10%)

Query: 359 PSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRS--PGSKARA 416
           P+ R+  S   S  P+  G S   TP +    R+     RT  RRSG SRS  P  + R+
Sbjct: 640 PARRSGRS--RSRTPARRGRSRSRTPARRGRSRS-----RTPARRSGRSRSRTPARRGRS 692

Query: 417 EGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGL 476
             R P        + + R    S    P     +  S   ++      TS RR       
Sbjct: 693 RSRTPRRGRSRSRSLVRR--GRSHSRTPQRRGRSGSS---SERKNKSRTSQRRSRSNSSP 747

Query: 477 EEFLSAMQSARGPTPSSPLP------SVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA 530
           E   S + S R  + SSP        S+  S+  S P         P   S+ G+ Q +A
Sbjct: 748 EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP-RRSRSGSSQPKA 806

Query: 531 AQR--HRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRR 574
             R   R S     P P    +  S     S  P   +  G  PR+
Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 70/274 (25%), Positives = 93/274 (33%), Gaps = 50/274 (18%)

Query: 342  SLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASI-----GR 396
            S  S G +S +   L+P +   +      S+ S V  +   TP +  S  AS      G 
Sbjct: 1375 STRSSGHSSSE---LSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL 1431

Query: 397  RRTELRRSGSSRSPG---------------------------SKARAEGRGPVTPLHLDL 429
             RT  RRS S  SPG                           S+ R+E      P  L  
Sbjct: 1432 PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ 1491

Query: 430  TQLHRLSLESSPDAPDH----TSETSHSPLYADPYT---PPATSHRRVTDVRGLEEFLSA 482
            T   R    SSP+  +       E S S    D  T    P     R    + L+   SA
Sbjct: 1492 TPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSA 1551

Query: 483  MQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGG 542
                R  + SSP        P        S P     +  K  L  R ++   GS+ +  
Sbjct: 1552 SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPE----VDSKSRLSPRRSR--SGSSPEVK 1605

Query: 543  PQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSR 576
             +P  AP+   S  + SPEP  P      PRRSR
Sbjct: 1606 DKPRAAPR-AQSGSDSSPEPKAP-APRALPRRSR 1637



 Score = 36.6 bits (83), Expect = 0.069
 Identities = 60/239 (25%), Positives = 84/239 (35%), Gaps = 30/239 (12%)

Query: 357 APPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARA 416
           AP S R   S    S  S+         D + S   S   +      +G S SP S  R 
Sbjct: 254 APKSRRAHRSTSADSASSS---------DTSRSRSRSAAAKTHTTALAGRSPSPASGRRG 304

Query: 417 EGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGL 476
           EG  P +      TQ    S E++   P    E           T P+ S  R +     
Sbjct: 305 EGDAPFSEPGTTSTQ-RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP 363

Query: 477 EEFLSAMQSARGPTP----SSPLPSVPVSVPA-SDPRSCSSGPAGPYLLSKKGALQS--- 528
                 +    G +P    ++PL   PV+ P+ + P    S P  P  L +  + +S   
Sbjct: 364 PAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPP 423

Query: 529 ----RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRS-PRRSRDPGYDH 582
                   RH  S+ +  P+P  AP    S RE S     P +  RS  R  RD  + H
Sbjct: 424 SPQPTKVSRHASSSPE-SPKPAPAP---GSHREISSS---PTSKNRSHGRAKRDKSHSH 475



 Score = 36.2 bits (82), Expect = 0.091
 Identities = 63/268 (23%), Positives = 92/268 (34%), Gaps = 15/268 (5%)

Query: 318  REGAPPLPGAESFPGSQV-MGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTV 376
            ++G P  P   S  GS   +  G G+ S    +    G    P T +       S P   
Sbjct: 1428 KDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK 1487

Query: 377  GCSSQHTPDQANSDRASIGRR--RTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHR 434
                   P   +     +  +    +  RSGS  S   K  A      TPL         
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR-----TPLGQRSRSGSS 1542

Query: 435  LSLESSPDA-PDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSS 493
              L+  P A P   SE+  SP        P     R      ++   S +   R  + SS
Sbjct: 1543 QELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS-KSRLSPRRSRSGSS 1601

Query: 494  P-LPSVPVSVPASDPRSCSSG-PAGPYLLSKKGALQSRAAQRHRGSAKDGGPQP---PDA 548
            P +   P + P +   S SS  P  P   +     +S ++ + RG + +G       P+ 
Sbjct: 1602 PEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH 1661

Query: 549  PQLVSSAREGSPEPWLPLTDGRSPRRSR 576
            P    +AR GS     P T  R+P R R
Sbjct: 1662 PPKSRTARRGSRSSPEPKTKSRTPPRRR 1689



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 59/222 (26%), Positives = 85/222 (38%), Gaps = 26/222 (11%)

Query: 338  SGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVP--------STVGCSSQH---TPDQ 386
            S R S S       D    AP +   S S PE   P        S  G SS+    +P+ 
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651

Query: 387  ANSDRASIG---RRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRLS--LESSP 441
            ++S  +S     + RT  R S SS  P +K+R   R   +    +LT+  RLS    S+ 
Sbjct: 1652 SSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSAS 1711

Query: 442  DAPDHTSET----SHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPS 497
             +P+  S T      SP  + P   PA   R     R      +   S RG +PS     
Sbjct: 1712 SSPETRSRTPPRHRRSPSVSSP--EPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPK--- 1766

Query: 498  VPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAK 539
             P  +  S  RS            + G+ QS + +R R  ++
Sbjct: 1767 -PRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 53/210 (25%), Positives = 74/210 (35%), Gaps = 27/210 (12%)

Query: 377 GCSSQHTPDQANSDRASIGRR---RTELRRSGSSRSPGSK----ARAEGRGPVTPLHLDL 429
           G S   TP +     +S  R+   RT  RRS S+ SP  K    +    R   +P     
Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770

Query: 430 TQLH-RLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARG 488
           ++L  R SL  S   P   S+T      +    P A S    T  R      S     + 
Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSR---TPPRRSRSSSSPPPKQKS 827

Query: 489 PTPS-------SPLPSVP---------VSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQ 532
            TPS       SP P V          ++ P ++ +S +      +  S    L+SR   
Sbjct: 828 KTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPS 887

Query: 533 RHRGSAKDGGPQPPDAPQLVSSAREGSPEP 562
           RH  S           P   S +R  SP+P
Sbjct: 888 RHSCSGSSPPRVKSSTPPRQSPSRSSSPQP 917



 Score = 33.1 bits (74), Expect = 0.77
 Identities = 58/230 (25%), Positives = 72/230 (31%), Gaps = 47/230 (20%)

Query: 345  SGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRS 404
            SG     DS     P    S S PE          +Q   D +   +A   R      RS
Sbjct: 1579 SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS 1638

Query: 405  GSSRSPGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSH-SPLYADPYTPP 463
            GSS        ++GRGP        +     S ESSP+ P  +      S    +P T  
Sbjct: 1639 GSS--------SKGRGP--------SPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS 1682

Query: 464  ATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKK 523
             T  RR +     E    A  S R                    RS SS P         
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRS-------------------RSASSSPE-------- 1715

Query: 524  GALQSRAAQRHRGSAKDGGPQPPDAPQLVSSARE-GSPEPWLPLTDGRSP 572
               +SR   RHR S     P+P +  +     R   SP        GRSP
Sbjct: 1716 --TRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSP 1763



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 23/77 (29%), Positives = 31/77 (40%), Gaps = 5/77 (6%)

Query: 370 SSVPSTVGCSSQHTPDQANSDRASI-----GRRRTELRRSGSSRSPGSKARAEGRGPVTP 424
           S  P+T G S   TP +    R+        R RT  RR   SR+P  + R+  R P   
Sbjct: 564 SRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARR 623

Query: 425 LHLDLTQLHRLSLESSP 441
                + + R S   SP
Sbjct: 624 RSRTRSPVRRRSRSRSP 640



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 3/89 (3%)

Query: 318  REGAPPLP---GAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPS 374
            REG PP P     +    S    S   S SS   +S  S   +  S+ +S S   SS PS
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650

Query: 375  TVGCSSQHTPDQANSDRASIGRRRTELRR 403
                  Q  P  A+  +   G RR+   R
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGERRSRSPR 2679



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 66/284 (23%), Positives = 93/284 (32%), Gaps = 34/284 (11%)

Query: 318  REGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVG 377
            R   PP     S P    M S R    S       S  L PP+       P S VPS   
Sbjct: 2406 RSRTPP-----SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPA----QDQPRSPVPSAFS 2456

Query: 378  ----CSSQHTPDQANSDRASIGRRRTELRRSG------SSRSPGSKARAEGRGPVT---- 423
                C    T   A S   S G   T    +G      S  +PG      G  P +    
Sbjct: 2457 DQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQ 2516

Query: 424  -PLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSA 482
             P  L   Q  +    SS  +   +S +S S   +   +  ++S         ++  + A
Sbjct: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEV-A 2575

Query: 483  MQSARGPTPSSPLPSV-----PVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGS 537
            ++    PTP+ P  +V     P   PA   R  SS  +     S   +  S ++     S
Sbjct: 2576 LKRVPSPTPA-PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2634

Query: 538  AKDGGPQPPDAPQLVSSAREGS---PEPWLPLTDGRSPRRSRDP 578
            +         +    S A+ G    P+P  P       RRSR P
Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP 2678


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 57/217 (26%), Positives = 73/217 (33%), Gaps = 46/217 (21%)

Query: 320 GAPPLPGAESFPGSQ---VMGSGRGSLSSGGQTSWDSG-CLAPPSTRTSHSLPE--SSVP 373
           GA P PG    PG     ++G   G   S G      G    PPS   SH +P   S+  
Sbjct: 8   GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSV--SHPMPTMGSTDF 65

Query: 374 STVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLH 433
              G    H P     D+  +     E    GS +  G +    G GP            
Sbjct: 66  PQEGMHQMHKPIDGIHDKGIV-----EDIHCGSMKGTGMRPPHPGMGP------------ 108

Query: 434 RLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSS 493
                  P +P       HS  Y  P+  P           G  E +S+  S  GPTP  
Sbjct: 109 -------PQSP----MDQHSQGYMSPHPSPL----------GAPEHVSSPMSGGGPTPPQ 147

Query: 494 PLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA 530
             PS P ++   DP++ S    GP   S     Q RA
Sbjct: 148 MPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRA 184


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 57/217 (26%), Positives = 73/217 (33%), Gaps = 46/217 (21%)

Query: 320 GAPPLPGAESFPGSQ---VMGSGRGSLSSGGQTSWDSG-CLAPPSTRTSHSLPE--SSVP 373
           GA P PG    PG     ++G   G   S G      G    PPS   SH +P   S+  
Sbjct: 8   GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSV--SHPMPTMGSTDF 65

Query: 374 STVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLH 433
              G    H P     D+  +     E    GS +  G +    G GP            
Sbjct: 66  PQEGMHQMHKPIDGIHDKGIV-----EDIHCGSMKGTGMRPPHPGMGP------------ 108

Query: 434 RLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSS 493
                  P +P       HS  Y  P+  P           G  E +S+  S  GPTP  
Sbjct: 109 -------PQSP----MDQHSQGYMSPHPSPL----------GAPEHVSSPMSGGGPTPPQ 147

Query: 494 PLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA 530
             PS P ++   DP++ S    GP   S     Q RA
Sbjct: 148 MPPSQPGALIPGDPQAMSQPNRGPSPFSPVQLHQLRA 184


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 88/335 (26%), Positives = 120/335 (35%), Gaps = 69/335 (20%)

Query: 314  AVTHREGAPPLPGAESFPGSQVMGSGR-GSLSSGGQTSWDSGCLAPPSTRTSHSLPESSV 372
            A  HR+   P+P      G+     G+  SL+S  Q    S         T    P++  
Sbjct: 917  ASLHRK--EPIPENPKSTGADTHPQGKYSSLASKAQDVQQS-----TDADTEGHSPKAQP 969

Query: 373  PSTVGCSSQHTPDQANSDR-ASIGRRRTELRR---------SGSSRSPGSKARAEGRGPV 422
             ST   +S   P  A S +  S+ RR T  R          + S   PG ++R  GR P 
Sbjct: 970  GSTDRHASPARPPAARSQQHPSVPRRMTPGRAPQQQPPPPVATSQHHPGPQSRDAGRSPS 1029

Query: 423  TPLHLDLTQLHRLSLESSPDAPDHTSE-TSHSPLYADPYTP------PATSHRRVTDVRG 475
             P  L LTQ  R         P  TS+  SHS   +DPYT       P     +  D +G
Sbjct: 1030 QP-RLSLTQAGR---------PRPTSQGRSHSS--SDPYTASSRGMLPTALQNQDEDAQG 1077

Query: 476  LEEFLSA---MQSARGPTPSSPLPSVPVSVP-------------ASDPRSCSSGPAGPYL 519
              +  S     Q  R P  ++       S+P               D RS     A P  
Sbjct: 1078 SYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVESPTGAGAGGDHRSQRGHAASPAR 1137

Query: 520  LSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPG 579
             S+ G  QSRA  R    A  G  +PP    L S +++         +         D G
Sbjct: 1138 PSRPGGPQSRA--RVPSRAAPGKSEPPSKRPLSSKSQQ---------SVSAEDDEEEDAG 1186

Query: 580  -YDHLWDETLSSSHQKCPQ----LGGPEASGGLVQ 609
             +    ++ LSSS  K P      GG +A G L +
Sbjct: 1187 FFKGGKEDLLSSSVPKWPSSSTPRGGKDADGSLAK 1221


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 66/279 (23%), Positives = 92/279 (32%), Gaps = 53/279 (18%)

Query: 312 LRAVTHREGAPPLPGAES----------FPGSQVMGSGRGSLSSGGQTSWDSGCLAPP-- 359
           +++  H  G+PP+PG             FPG++    G GS+     +S       PP  
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253

Query: 360 --STRTSHSLPESSVPSTVGCSSQHT------PDQANSDRASIGRRRTELRRSGSSRSPG 411
              +R     P    P      S H       P Q N        R +   ++     P 
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313

Query: 412 SKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVT 471
           S+       P +  + +  +L + +L  S   P   S     PL      PP  S R   
Sbjct: 314 SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPL------PPPPSERPPP 367

Query: 472 DVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSG-PAGPYLLSKKGALQSRA 530
            VR              P  S PLP  P   P S   S S   PA P L S+ G    R+
Sbjct: 368 PVRD------------PPGRSGPLPPPP---PVSRNGSTSRALPATPQLPSRSGVDSPRS 412

Query: 531 AQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDG 569
                      GP+PP  P   S+     P P   + +G
Sbjct: 413 -----------GPRPPLPPDRPSAGAPPPPPPSTSIRNG 440



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 75/286 (26%), Positives = 98/286 (34%), Gaps = 43/286 (15%)

Query: 312 LRAVTHREG-----APPL--PGAESF---PGSQVMGSGRGSLSSGGQTSWD---SGCLAP 358
           LR+  +R+       PPL  PG  S    P S   G GR  + S G  S          P
Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170

Query: 359 PSTRTSHSLPES---SVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKAR 415
           P      S P+S    VPST     Q +P    S     G R+     +     PG++  
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPR-PIQSSPHNRGSPPVPGGPRQPSPGPTPPP-FPGNRGT 228

Query: 416 AEGRGPV--TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDV 473
           A G G +  +PL       +R  L   P  P    +    P       PP   +R     
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPL---PPTPSRALDDKPPP------PPPPVGNRPSIHR 279

Query: 474 RGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS-RAAQ 532
             +       Q+ + P PS+P PS     P   P     GP  P   S  G  ++ R  Q
Sbjct: 280 EAVPP--PPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRLPQ 336

Query: 533 RHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 578
           R+   +          P L S  R G   P  P    R P   RDP
Sbjct: 337 RNLSLSS-------STPPLPSPGRSG---PLPPPPSERPPPPVRDP 372


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 66/279 (23%), Positives = 92/279 (32%), Gaps = 53/279 (18%)

Query: 312 LRAVTHREGAPPLPGAES----------FPGSQVMGSGRGSLSSGGQTSWDSGCLAPP-- 359
           +++  H  G+PP+PG             FPG++    G GS+     +S       PP  
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253

Query: 360 --STRTSHSLPESSVPSTVGCSSQHT------PDQANSDRASIGRRRTELRRSGSSRSPG 411
              +R     P    P      S H       P Q N        R +   ++     P 
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPP 313

Query: 412 SKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVT 471
           S+       P +  + +  +L + +L  S   P   S     PL      PP  S R   
Sbjct: 314 SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPL------PPPPSERPPP 367

Query: 472 DVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSG-PAGPYLLSKKGALQSRA 530
            VR              P  S PLP  P   P S   S S   PA P L S+ G    R+
Sbjct: 368 PVRD------------PPGRSGPLPPPP---PVSRNGSTSRALPATPQLPSRSGVDSPRS 412

Query: 531 AQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDG 569
                      GP+PP  P   S+     P P   + +G
Sbjct: 413 -----------GPRPPLPPDRPSAGAPPPPPPSTSIRNG 440



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 75/286 (26%), Positives = 98/286 (34%), Gaps = 43/286 (15%)

Query: 312 LRAVTHREG-----APPL--PGAESF---PGSQVMGSGRGSLSSGGQTSWD---SGCLAP 358
           LR+  +R+       PPL  PG  S    P S   G GR  + S G  S          P
Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170

Query: 359 PSTRTSHSLPES---SVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKAR 415
           P      S P+S    VPST     Q +P    S     G R+     +     PG++  
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPR-PIQSSPHNRGSPPVPGGPRQPSPGPTPPP-FPGNRGT 228

Query: 416 AEGRGPV--TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDV 473
           A G G +  +PL       +R  L   P  P    +    P       PP   +R     
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPL---PPTPSRALDDKPPP------PPPPVGNRPSIHR 279

Query: 474 RGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS-RAAQ 532
             +       Q+ + P PS+P PS     P   P     GP  P   S  G  ++ R  Q
Sbjct: 280 EAVPP--PPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDETPRLPQ 336

Query: 533 RHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 578
           R+   +          P L S  R G   P  P    R P   RDP
Sbjct: 337 RNLSLSS-------STPPLPSPGRSG---PLPPPPSERPPPPVRDP 372


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 31/78 (39%), Positives = 36/78 (46%), Gaps = 4/78 (5%)

Query: 487 RGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA-AQRHRGSAKDGGPQP 545
           RGP  S  L S P   PAS PR  S  P G    S  G   S + A   RGS  + G +P
Sbjct: 304 RGPEDSWLLLSAPGPTPAS-PRPAS--PCGKRRYSSSGTPSSASPALSRRGSLGEEGSEP 360

Query: 546 PDAPQLVSSAREGSPEPW 563
           P  P L  +   GSP P+
Sbjct: 361 PPPPPLPLARDPGSPGPF 378


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 31/78 (39%), Positives = 36/78 (46%), Gaps = 4/78 (5%)

Query: 487 RGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA-AQRHRGSAKDGGPQP 545
           RGP  S  L S P   PAS PR  S  P G    S  G   S + A   RGS  + G +P
Sbjct: 241 RGPEDSWLLLSAPGPTPAS-PRPAS--PCGKRRYSSSGTPSSASPALSRRGSLGEEGSEP 297

Query: 546 PDAPQLVSSAREGSPEPW 563
           P  P L  +   GSP P+
Sbjct: 298 PPPPPLPLARDPGSPGPF 315


>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
            sapiens]
          Length = 1309

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 42/138 (30%), Positives = 54/138 (39%), Gaps = 34/138 (24%)

Query: 475  GLEEFLSAMQSARG-------PTPS----SPLPSVPVSVPASDPRSC--SSGPAGPYLLS 521
            GL   LS+ +S  G       P+P+    SP P VP    AS P +   SS PA P    
Sbjct: 1095 GLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSASPSSSSPASP---- 1150

Query: 522  KKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSA----------------REGSPEPWLP 565
               A  +R +  H  +AK G P+P    +  +S+                R  SP P  P
Sbjct: 1151 -AAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPRSPSPLPGHP 1209

Query: 566  LTDGRSPRRSRDPGYDHL 583
                RSPR  R    D L
Sbjct: 1210 PAPARSPRLRRGQSADKL 1227


>gi|33636717 hypothetical protein LOC80256 [Homo sapiens]
          Length = 538

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 60/237 (25%), Positives = 77/237 (32%), Gaps = 83/237 (35%)

Query: 318 REGAPPL-PGAESFPGSQVMGSGRGSLS--------------SGGQTSWDSGCLAPPSTR 362
           REG PP  P      G +  G G G  S              S   +SW SG  +PP   
Sbjct: 88  REGLPPEEPSTVGLLGPEGPGLGLGVASQHFSHRGLCVVEQRSSVTSSWTSGAWSPPCP- 146

Query: 363 TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPV 422
                     PS   C++ HT D A+ D                    GS   + G  P 
Sbjct: 147 ----------PSNASCNTLHTRDWASPDPGG----------------QGSLGESPGPAPP 180

Query: 423 TPLHLDLTQLHRLSL--ESSPDA---------PDHTSETS--HSPLYADPYTPPATSHRR 469
             LH   T LH L+     SP A         P  +  T+  HSP     +TPP      
Sbjct: 181 GQLHTLDTDLHSLAQIGGKSPVAGVGNGGSLWPRESPGTANGHSP----EHTPP------ 230

Query: 470 VTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGAL 526
                             GP P  P P+    +PA +    SS   GP    ++G+L
Sbjct: 231 ------------------GPGPPGPCPTKRRLLPAGEAPDVSSEEEGPAPRRRRGSL 269


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 41/158 (25%), Positives = 59/158 (37%), Gaps = 6/158 (3%)

Query: 363  TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTEL-RRSGSSRSPGSKARAEGRGP 421
            T+  L E S       +S  T   A    A +G   T     SGS+ +  S AR+   G 
Sbjct: 1349 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 1408

Query: 422  V---TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 478
            V   TP  L  +     +L  SP  P  + ++  +  Y  P +P AT     T   G+ E
Sbjct: 1409 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSE 1466

Query: 479  FLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAG 516
              S   S  G T ++  P    +   S   + S    G
Sbjct: 1467 ESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 1504



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 41/158 (25%), Positives = 59/158 (37%), Gaps = 6/158 (3%)

Query: 363  TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTEL-RRSGSSRSPGSKARAEGRGP 421
            T+  L E S       +S  T   A    A +G   T     SGS+ +  S AR+   G 
Sbjct: 2906 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2965

Query: 422  V---TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 478
            V   TP  L  +     +L  SP  P  + ++  +  Y  P +P AT     T   G+ E
Sbjct: 2966 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSE 3023

Query: 479  FLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAG 516
              S   S  G T ++  P    +   S   + S    G
Sbjct: 3024 ESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQG 3061



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 42/155 (27%), Positives = 61/155 (39%), Gaps = 7/155 (4%)

Query: 363  TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTEL-RRSGSSRSPGSKARAEGRGP 421
            T+  L E S       +S  T   A    A +G   T     SGS+ +  S AR+   G 
Sbjct: 3989 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 4048

Query: 422  V---TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 478
            V   TP  L  +     +L  SP  P  + ++  +  Y  P +P AT     T   G+ E
Sbjct: 4049 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSE 4106

Query: 479  FLSAMQSARGPTPSSPLP-SVPVSVPASDPRSCSS 512
              S   S  G T ++  P S   S  + +P +  S
Sbjct: 4107 ESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHS 4141



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 38/138 (27%), Positives = 54/138 (39%), Gaps = 6/138 (4%)

Query: 363  TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTEL-RRSGSSRSPGSKARAEGRGP 421
            T+  L E S       +S  T   A    A +G   T     SGS+ +  S AR+   G 
Sbjct: 2432 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2491

Query: 422  V---TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 478
            V   TP  L  +     +L  SP  P  + ++  +  Y  P +P AT     T   G+ E
Sbjct: 2492 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSE 2549

Query: 479  FLSAMQSARGPTPSSPLP 496
              S   S  G T ++  P
Sbjct: 2550 ESSTSHSQPGSTHTTAFP 2567



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 60/240 (25%), Positives = 88/240 (36%), Gaps = 27/240 (11%)

Query: 358  PPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAE 417
            P S+ TS    +S++  +   +S  TP  A+S  +  G   T      S  SPGS     
Sbjct: 1177 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT------SRISPGSTEITT 1230

Query: 418  GRGPVTPLHLDLTQLHRLSLESSPDAPDHT-SETSHSPL-----YADPYTPPATSHRRV- 470
              G  T   L        +  SSP +P  T S  S + L          + P ++H  V 
Sbjct: 1231 LPGSTTTPGLSEAS---TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 1287

Query: 471  ---TDVRGL-EEFLSAMQSARGPTPSSPLP-SVPVSVPASDPRSCSSGPAGPY-LLSKKG 524
               T   GL EE  +   S+RG T ++  P S   SV   +P +  S PA  +  L  + 
Sbjct: 1288 PASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTED 1347

Query: 525  ALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGR-----SPRRSRDPG 579
            +  S   +                P  +++A  G      P + G      SP RS   G
Sbjct: 1348 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 1407



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 59/240 (24%), Positives = 87/240 (36%), Gaps = 27/240 (11%)

Query: 358  PPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAE 417
            P S+ TS    +S++  +   +S  TP  A+S  +  G   T      S  SPGS     
Sbjct: 2260 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT------SRISPGSTEITT 2313

Query: 418  GRGPVTPLHLDLTQLHRLSLESSPDAPDHT-SETSHSPL-----YADPYTPPATSHRRV- 470
              G  T   L        +  SSP +P  T S  S + L          + P ++H  V 
Sbjct: 2314 LPGSTTTPGLSEAS---TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 2370

Query: 471  ---TDVRGL-EEFLSAMQSARGPTPSSPLPSVP-VSVPASDPRSCSSGPAGPY-LLSKKG 524
               T   GL EE  +   S+ G T ++  P  P  SV   +P +  S PA  +  L  + 
Sbjct: 2371 PASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTED 2430

Query: 525  ALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGR-----SPRRSRDPG 579
            +  S   +                P  +++A  G      P + G      SP RS   G
Sbjct: 2431 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2490



 Score = 29.6 bits (65), Expect = 8.5
 Identities = 59/240 (24%), Positives = 87/240 (36%), Gaps = 27/240 (11%)

Query: 358  PPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAE 417
            P S+ TS    +S++  +   +S  TP  A+S  +  G   T      S  SPGS     
Sbjct: 2734 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT------SRISPGSTEITT 2787

Query: 418  GRGPVTPLHLDLTQLHRLSLESSPDAPDHT-SETSHSPL-----YADPYTPPATSHRRV- 470
              G  T   L        +  SSP +P  T S  S + L          + P ++H  V 
Sbjct: 2788 LPGSTTTPGLSEAS---TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 2844

Query: 471  ---TDVRGL-EEFLSAMQSARGPTPSSPLP-SVPVSVPASDPRSCSSGPAGPY-LLSKKG 524
               T   GL EE  +   S+ G T ++  P S   SV   +P +  S PA  +  L  + 
Sbjct: 2845 PASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTED 2904

Query: 525  ALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGR-----SPRRSRDPG 579
            +  S   +                P  +++A  G      P + G      SP RS   G
Sbjct: 2905 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2964


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 41/158 (25%), Positives = 59/158 (37%), Gaps = 6/158 (3%)

Query: 363 TSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTEL-RRSGSSRSPGSKARAEGRGP 421
           T+  L E S       +S  T   A    A +G   T     SGS+ +  S AR+   G 
Sbjct: 836 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 895

Query: 422 V---TPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 478
           V   TP  L  +     +L  SP  P  + ++  +  Y  P +P AT     T   G+ E
Sbjct: 896 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGVSE 953

Query: 479 FLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAG 516
             S   S  G T ++  P    +   S   + S    G
Sbjct: 954 ESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQG 991



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 60/240 (25%), Positives = 88/240 (36%), Gaps = 27/240 (11%)

Query: 358 PPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAE 417
           P S+ TS    +S++  +   +S  TP  A+S  +  G   T      S  SPGS     
Sbjct: 664 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT------SRISPGSTEITT 717

Query: 418 GRGPVTPLHLDLTQLHRLSLESSPDAPDHT-SETSHSPL-----YADPYTPPATSHRRV- 470
             G  T   L        +  SSP +P  T S  S + L          + P ++H  V 
Sbjct: 718 LPGSTTTPGLSEAS---TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 774

Query: 471 ---TDVRGL-EEFLSAMQSARGPTPSSPLP-SVPVSVPASDPRSCSSGPAGPY-LLSKKG 524
              T   GL EE  +   S+RG T ++  P S   SV   +P +  S PA  +  L  + 
Sbjct: 775 PASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTED 834

Query: 525 ALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGR-----SPRRSRDPG 579
           +  S   +                P  +++A  G      P + G      SP RS   G
Sbjct: 835 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 894


>gi|38176151 Lunapark [Homo sapiens]
          Length = 428

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 28/74 (37%), Positives = 31/74 (41%), Gaps = 5/74 (6%)

Query: 481 SAMQSARGPTPSSPLPSVPVSVPASD-PRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAK 539
           +A Q    PTP+SP    P  VP S  P   SS P GP   +   AL S    RH GS  
Sbjct: 170 TAAQRNLSPTPASPNQGPPPQVPVSPGPPKDSSAPGGPPERTVTPALSSNVLPRHLGSPA 229

Query: 540 DGGP----QPPDAP 549
              P     PP  P
Sbjct: 230 TSVPGMGLHPPGPP 243


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 67/279 (24%), Positives = 93/279 (33%), Gaps = 19/279 (6%)

Query: 322 PPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQ 381
           PP P     PG    GS R   S     S  SG  +   T T      +  P++ G +  
Sbjct: 551 PPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQP 610

Query: 382 HTPDQANSDR---ASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRLSLE 438
             P++  S R   AS+    T L  S S  +P  ++   G   +TPL        R  + 
Sbjct: 611 PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRS---GPQILTPLG------DRFVIP 661

Query: 439 SSPDAPDHTSETSHSPLYADPYTP----PATSHRRVTDVRGLEEFLSAMQSARGPTPSSP 494
             P  P   S     P   +P  P    PA     V+      +     Q+   P   SP
Sbjct: 662 PHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESP 721

Query: 495 LPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGG--PQPPDAPQLV 552
           + S   S P S P S    P  P    +       A++      +D    P PP AP+  
Sbjct: 722 VISKDQSPPPSPPPSYHP-PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQ 780

Query: 553 SSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSS 591
             +    P P        SP  +   G   L     +SS
Sbjct: 781 DLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASS 819


>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
          Length = 1167

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 55/223 (24%), Positives = 85/223 (38%), Gaps = 34/223 (15%)

Query: 314  AVTHREGAPP---LPGAESFP-GSQVMGSGR----GSLSSGGQTSWDSGCLAPPSTRTSH 365
            A+T ++  PP   + G  + P G +  G  R    G    G Q  W S   A P   T+H
Sbjct: 855  AITEKD--PPGVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVLPTTH 912

Query: 366  SLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPL 425
            +     VP  +  + +HTP    +D   IG           + S G+K +      VT  
Sbjct: 913  N---HKVPVLISPTLKHTP----ADVQLIG-----------TDSQGNKFKLLSEHQVTSS 954

Query: 426  HLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPP----ATSHRRVTDVRGLEEFLS 481
              D  +  R+  + +P  P       H  + +DP   P    A      T   G +  L 
Sbjct: 955  G-DKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQEGGKKAALG 1013

Query: 482  AMQ-SARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKK 523
            A+  S +   P  P P VP+   +  P   ++G AG  +  +K
Sbjct: 1014 AVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRK 1056


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,768,890
Number of Sequences: 37866
Number of extensions: 1675066
Number of successful extensions: 9803
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 457
Number of HSP's that attempted gapping in prelim test: 8942
Number of HSP's gapped (non-prelim): 1261
length of query: 611
length of database: 18,247,518
effective HSP length: 108
effective length of query: 503
effective length of database: 14,157,990
effective search space: 7121468970
effective search space used: 7121468970
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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