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Search of human proteins with 237757326
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
(1526 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 3065 0.0
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 3026 0.0
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 2491 0.0
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 2485 0.0
gi|26190608 synaptojanin 2 [Homo sapiens] 1187 0.0
gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs... 211 6e-54
gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso... 206 1e-52
gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso... 206 1e-52
gi|190014578 suppressor of actin 1 [Homo sapiens] 206 1e-52
gi|7662414 inositol polyphosphate-5-phosphatase F [Homo sapiens] 199 1e-50
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ... 174 8e-43
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ... 174 8e-43
gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas... 160 1e-38
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 157 1e-37
gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] 139 2e-32
gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho... 133 1e-30
gi|7662034 Sac domain-containing inositol phosphatase 3 [Homo sa... 132 3e-30
gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H... 125 3e-28
gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho... 125 3e-28
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 97 2e-19
gi|116284392 mucin 2 precursor [Homo sapiens] 94 8e-19
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 93 2e-18
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 93 2e-18
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 93 2e-18
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 93 2e-18
gi|163965366 nascent polypeptide-associated complex alpha subuni... 92 5e-18
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 90 1e-17
gi|47132519 Ras association and pleckstrin homology domains 1 is... 90 1e-17
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 87 9e-17
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 87 1e-16
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 3065 bits (7946), Expect = 0.0
Identities = 1526/1526 (100%), Positives = 1526/1526 (100%)
Query: 1 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 60
MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY
Sbjct: 1 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 60
Query: 61 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 120
GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR
Sbjct: 61 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 120
Query: 121 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 180
KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL
Sbjct: 121 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 180
Query: 181 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 240
RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD
Sbjct: 181 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 240
Query: 241 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 300
DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN
Sbjct: 241 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 300
Query: 301 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 360
LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD
Sbjct: 301 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 360
Query: 361 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 420
YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR
Sbjct: 361 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 420
Query: 421 FQEVFRSMWSVNGDSISKIYAGTGALEGKAKAGKLKDGARSVTRTIQNNFFDSSKQEAID 480
FQEVFRSMWSVNGDSISKIYAGTGALEGKAKAGKLKDGARSVTRTIQNNFFDSSKQEAID
Sbjct: 421 FQEVFRSMWSVNGDSISKIYAGTGALEGKAKAGKLKDGARSVTRTIQNNFFDSSKQEAID 480
Query: 481 VLLLGNTLNSDLADKARALLTTGSLRASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGG 540
VLLLGNTLNSDLADKARALLTTGSLRASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGG
Sbjct: 481 VLLLGNTLNSDLADKARALLTTGSLRASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGG 540
Query: 541 KQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSAST 600
KQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSAST
Sbjct: 541 KQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSAST 600
Query: 601 TNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGA 660
TNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGA
Sbjct: 601 TNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGA 660
Query: 661 TGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYV 720
TGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYV
Sbjct: 661 TGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYV 720
Query: 721 FWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYK 780
FWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYK
Sbjct: 721 FWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYK 780
Query: 781 YDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGT 840
YDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGT
Sbjct: 781 YDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGT 840
Query: 841 LLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLP 900
LLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLP
Sbjct: 841 LLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLP 900
Query: 901 ENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTIT 960
ENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTIT
Sbjct: 901 ENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTIT 960
Query: 961 IALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEEL 1020
IALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEEL
Sbjct: 961 IALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEEL 1020
Query: 1021 LPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1080
LPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP
Sbjct: 1021 LPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1080
Query: 1081 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPG 1140
IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPG
Sbjct: 1081 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPG 1140
Query: 1141 PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF 1200
PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF
Sbjct: 1141 PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF 1200
Query: 1201 PPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVK 1260
PPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVK
Sbjct: 1201 PPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVK 1260
Query: 1261 TNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVL 1320
TNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVL
Sbjct: 1261 TNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVL 1320
Query: 1321 SSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEAT 1380
SSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEAT
Sbjct: 1321 SSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEAT 1380
Query: 1381 SWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEE 1440
SWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEE
Sbjct: 1381 SWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEE 1440
Query: 1441 EDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLP 1500
EDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLP
Sbjct: 1441 EDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLP 1500
Query: 1501 PGTSPPVDPFTTLASKASPTLDFTER 1526
PGTSPPVDPFTTLASKASPTLDFTER
Sbjct: 1501 PGTSPPVDPFTTLASKASPTLDFTER 1526
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 3026 bits (7845), Expect = 0.0
Identities = 1523/1576 (96%), Positives = 1523/1576 (96%), Gaps = 53/1576 (3%)
Query: 1 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 60
MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY
Sbjct: 40 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 99
Query: 61 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 120
GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR
Sbjct: 100 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 159
Query: 121 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 180
KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL
Sbjct: 160 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 219
Query: 181 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 240
RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD
Sbjct: 220 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 279
Query: 241 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 300
DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN
Sbjct: 280 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 339
Query: 301 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 360
LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD
Sbjct: 340 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 399
Query: 361 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 420
YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR
Sbjct: 400 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 459
Query: 421 FQEVFRSMWSVNGDSISKIYAGTGALEGKAKAGKLKDGARSVTRTIQNNFFDSSKQEAID 480
FQEVFRSMWSVNGDSISKIYAGTGALEGKAK LKDGARSVTRTIQNNFFDSSKQEAID
Sbjct: 460 FQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAID 516
Query: 481 VLLLGNTLNSDLADKARALLTTGSLR--------ASSKVLKSMCENFYKYSKPKKIRVCV 532
VLLLGNTLNSDLADKARALLTTGSLR ASSKVLKSMCENFYKYSKPKKIRVCV
Sbjct: 517 VLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCV 576
Query: 533 GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA 592
GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA
Sbjct: 577 GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA 636
Query: 593 GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT 652
GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT
Sbjct: 637 GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT 696
Query: 653 VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR 712
VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR
Sbjct: 697 VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR 756
Query: 713 MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK 772
MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK
Sbjct: 757 MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK 816
Query: 773 VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI 832
VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI
Sbjct: 817 VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI 876
Query: 833 LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL 892
LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL
Sbjct: 877 LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL 936
Query: 893 VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK 952
VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK
Sbjct: 937 VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK 996
Query: 953 ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD 1012
ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD
Sbjct: 997 ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD 1056
Query: 1013 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG 1072
YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG
Sbjct: 1057 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG 1116
Query: 1073 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPS------- 1125
PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPS
Sbjct: 1117 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAP 1176
Query: 1126 -----------------------------------GRSQPSPQAGLAGPGPAGYSTARPT 1150
GRSQPSPQAGLAGPGPAGYSTARPT
Sbjct: 1177 TRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPT 1236
Query: 1151 IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1210
IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA
Sbjct: 1237 IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1296
Query: 1211 QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRE 1270
QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRE
Sbjct: 1297 QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRE 1356
Query: 1271 SPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMP 1330
SPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMP
Sbjct: 1357 SPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMP 1416
Query: 1331 PIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVT 1390
PIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVT
Sbjct: 1417 PIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVT 1476
Query: 1391 ISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSK 1450
ISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSK
Sbjct: 1477 ISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSK 1536
Query: 1451 SACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPF 1510
SACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPF
Sbjct: 1537 SACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSPPVDPF 1596
Query: 1511 TTLASKASPTLDFTER 1526
TTLASKASPTLDFTER
Sbjct: 1597 TTLASKASPTLDFTER 1612
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 2491 bits (6457), Expect = 0.0
Identities = 1255/1292 (97%), Positives = 1255/1292 (97%), Gaps = 37/1292 (2%)
Query: 1 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 60
MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY
Sbjct: 1 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 60
Query: 61 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 120
GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR
Sbjct: 61 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 120
Query: 121 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 180
KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL
Sbjct: 121 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 180
Query: 181 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 240
RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD
Sbjct: 181 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 240
Query: 241 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 300
DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN
Sbjct: 241 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 300
Query: 301 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 360
LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD
Sbjct: 301 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 360
Query: 361 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 420
YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR
Sbjct: 361 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 420
Query: 421 FQEVFRSMWSVNGDSISKIYAGTGALEGKAKAGKLKDGARSVTRTIQNNFFDSSKQEAID 480
FQEVFRSMWSVNGDSISKIYAGTGALEGKAK LKDGARSVTRTIQNNFFDSSKQEAID
Sbjct: 421 FQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAID 477
Query: 481 VLLLGNTLNSDLADKARALLTTGSLR--------ASSKVLKSMCENFYKYSKPKKIRVCV 532
VLLLGNTLNSDLADKARALLTTGSLR ASSKVLKSMCENFYKYSKPKKIRVCV
Sbjct: 478 VLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCV 537
Query: 533 GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA 592
GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA
Sbjct: 538 GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA 597
Query: 593 GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT 652
GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT
Sbjct: 598 GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT 657
Query: 653 VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR 712
VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR
Sbjct: 658 VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR 717
Query: 713 MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK 772
MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK
Sbjct: 718 MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK 777
Query: 773 VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI 832
VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI
Sbjct: 778 VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI 837
Query: 833 LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL 892
LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL
Sbjct: 838 LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL 897
Query: 893 VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK 952
VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK
Sbjct: 898 VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK 957
Query: 953 ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD 1012
ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD
Sbjct: 958 ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD 1017
Query: 1013 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG 1072
YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG
Sbjct: 1018 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG 1077
Query: 1073 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPS------- 1125
PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPS
Sbjct: 1078 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAP 1137
Query: 1126 -------------------GRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHAR 1166
GRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHAR
Sbjct: 1138 TRKEFGAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHAR 1197
Query: 1167 ASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQ 1226
ASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQ
Sbjct: 1198 ASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQ 1257
Query: 1227 SGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1258
SGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ
Sbjct: 1258 SGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1289
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 2485 bits (6441), Expect = 0.0
Identities = 1255/1308 (95%), Positives = 1255/1308 (95%), Gaps = 53/1308 (4%)
Query: 1 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 60
MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY
Sbjct: 40 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 99
Query: 61 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 120
GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR
Sbjct: 100 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 159
Query: 121 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 180
KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL
Sbjct: 160 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 219
Query: 181 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 240
RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD
Sbjct: 220 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 279
Query: 241 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 300
DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN
Sbjct: 280 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 339
Query: 301 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 360
LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD
Sbjct: 340 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 399
Query: 361 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 420
YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR
Sbjct: 400 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 459
Query: 421 FQEVFRSMWSVNGDSISKIYAGTGALEGKAKAGKLKDGARSVTRTIQNNFFDSSKQEAID 480
FQEVFRSMWSVNGDSISKIYAGTGALEGKAK LKDGARSVTRTIQNNFFDSSKQEAID
Sbjct: 460 FQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAID 516
Query: 481 VLLLGNTLNSDLADKARALLTTGSLR--------ASSKVLKSMCENFYKYSKPKKIRVCV 532
VLLLGNTLNSDLADKARALLTTGSLR ASSKVLKSMCENFYKYSKPKKIRVCV
Sbjct: 517 VLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCV 576
Query: 533 GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA 592
GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA
Sbjct: 577 GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA 636
Query: 593 GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT 652
GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT
Sbjct: 637 GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT 696
Query: 653 VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR 712
VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR
Sbjct: 697 VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR 756
Query: 713 MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK 772
MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK
Sbjct: 757 MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK 816
Query: 773 VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI 832
VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI
Sbjct: 817 VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI 876
Query: 833 LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL 892
LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL
Sbjct: 877 LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL 936
Query: 893 VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK 952
VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK
Sbjct: 937 VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK 996
Query: 953 ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD 1012
ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD
Sbjct: 997 ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD 1056
Query: 1013 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG 1072
YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG
Sbjct: 1057 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG 1116
Query: 1073 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPS------- 1125
PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPS
Sbjct: 1117 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAP 1176
Query: 1126 -----------------------------------GRSQPSPQAGLAGPGPAGYSTARPT 1150
GRSQPSPQAGLAGPGPAGYSTARPT
Sbjct: 1177 TRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPT 1236
Query: 1151 IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1210
IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA
Sbjct: 1237 IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1296
Query: 1211 QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1258
QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ
Sbjct: 1297 QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1344
>gi|26190608 synaptojanin 2 [Homo sapiens]
Length = 1496
Score = 1187 bits (3070), Expect = 0.0
Identities = 642/1400 (45%), Positives = 899/1400 (64%), Gaps = 91/1400 (6%)
Query: 1 MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDA 59
MA SKG R+ +L S+++E R +++CL+FE+G VA L+ EKE IKG Y K+ DA
Sbjct: 1 MALSKGLRLLGRLGAEGDCSVLLEARGRDDCLLFEAGTVATLAPEEKEVIKGQYGKLTDA 60
Query: 60 YGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEV 119
YG LG LRL G T L +LVLVTGC SVG+I ++E++++T+T+F L+ ++ +E+R+ +
Sbjct: 61 YGCLGELRLKSGGTSLSFLVLVTGCTSVGRIPDAEIYKITATDFYPLQEEAKEEERLIAL 120
Query: 120 RKVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTT-DNRFFWNQSLHLHLKHYGVNCDDW 178
+K+L+SG FYF+W G DL++ + + + N FFWNQ LH+ L+ + V+C DW
Sbjct: 121 KKILSSGVFYFSWPNDGSRFDLTVRTQKQGDDSSEWGNSFFWNQLLHVPLRQHQVSCCDW 180
Query: 179 LLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVY 238
LL+++CG V IRT+YA+HKQAKACL+SR+SCER GTRF+ RG NDDGHV+NFVETEQ++Y
Sbjct: 181 LLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQMIY 240
Query: 239 LDDSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQII 298
+DD VSSF+QIRGSVPLFWEQPGLQVGSH +R+ RG EANAPAFDRH LK YG+Q++
Sbjct: 241 MDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVV 300
Query: 299 VNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQ-K 357
VNLLGS+ GE +L++AF+ L AS HA D M+NFD+HQ KGGK EKL ++L+PQ++
Sbjct: 301 VNLLGSRGGEEVLNRAFKKLLWASCHAGDTPMINFDFHQFAKGGKLEKLETLLRPQLKLH 360
Query: 358 FLDYGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQL 417
+ D+ F + R Q GT+R NCLDCLDRTN+VQ+F+ LE+L QL+ LGL+ KP +
Sbjct: 361 WEDFDVFTKGENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVLHLQLKTLGLSSKP-I 419
Query: 418 VTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAKAGKLKDGARSVTRTIQNNFFDSSKQE 477
V RF E F++MWS+NG S+SK++ G+ ALEGKAK GKLKDGARS++RTIQ+NFFD KQE
Sbjct: 420 VDRFVESFKAMWSLNGHSLSKVFTGSRALEGKAKVGKLKDGARSMSRTIQSNFFDGVKQE 479
Query: 478 AIDVLLLGNTLNSDLADKARALLTTGSLRASSKVLKSMCENFYKYSKPKKIRVCVGTWNV 537
AI +LL+G+ ++ADK LL + +L + ++LK+M E +++ K+IR+ +GTWNV
Sbjct: 480 AIKLLLVGDVYGEEVADKGGMLLDSTALLVTPRILKAMTERQSEFTNFKRIRIAMGTWNV 539
Query: 538 NGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVS 597
NGGKQFRS + LTDWLLD+P+L+G + QD S P DIFA+GFEEMVEL+AGNIV+
Sbjct: 540 NGGKQFRSNVLRTAELTDWLLDSPQLSGATDSQDD-SSPADIFAVGFEEMVELSAGNIVN 598
Query: 598 ASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGM 657
ASTTN+K+W +LQK ISR ++Y+LL S QLVGVCL++F+RP H PFIRDVA+DTVKTGM
Sbjct: 599 ASTTNKKMWGEQLQKAISRSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVAIDTVKTGM 658
Query: 658 GGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSH 717
GG GNKGAV IR FH+TS CF+CSH AGQSQVKERNED+ EI +KL FPMGR +FSH
Sbjct: 659 GGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYKEITQKLCFPMGRNVFSH 718
Query: 718 DYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAP 777
DYVFWCGDFNYRIDL EEV +++Q+W L+ DQL QK++G++F+ F EG + F P
Sbjct: 719 DYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFHEGAINFGP 778
Query: 778 TYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWT 837
TYKYD+ S YDTS+KCRTPAWTDRVLW R+K PFD++A +L+LL++ ++K+ +TW+
Sbjct: 779 TYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVDTKVRHTWS 838
Query: 838 PGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKS 897
PG L +YGRAEL+ SDHRPV+A++++++ EV+ R+ +++EV + QGP D TV+V+++S
Sbjct: 839 PGALQYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSFQGPLDATVVVNLQS 898
Query: 898 -SLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLN 956
+L E N F + L EL+Q S+G ++L+R + +M VTF + SAL+VL ++G ++
Sbjct: 899 PTLEEKNEFPEDLRTELMQTLGSYGTIVLVRINQGQMLVTFADSHSALSVLDVDGMKVKG 958
Query: 957 RTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAE 1016
R + I K+ DW+K L EE+ ++ S+A S T+++ L E+ D E + D +
Sbjct: 959 RAVKIRPKTKDWLKGLREEIIRKRDSMAPVSPTANSCLLEENFDFTSLDYESEGDILEDD 1018
Query: 1017 VEELLPQHLQPS-SSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS 1075
+ L+ + QP S S LG +S+ P P+ PS++P+ T
Sbjct: 1019 EDYLVDEFNQPGVSDSELG-------------GDDLSDVPGPTALAPPSKSPALT----K 1061
Query: 1076 AQSSPIDAQPATPLPQKDPAQPL-EPKRPPPPRPVAPPTR---PAPPQRPPPPSGR--SQ 1129
+ P A + K + + E + P R ++ P R P PPQRPPPP+G +
Sbjct: 1062 KKQHPTYKDDADLVELKRELEAVGEFRHRSPSRSLSVPNRPRPPQPPQRPPPPTGLMVKK 1121
Query: 1130 PSPQAGLAGPGPAGYS---TAR-----PTIPPRAGV----------ISAPQSHARASAGR 1171
+ A ++ YS TAR P PP+A I + +A R
Sbjct: 1122 SASDASISSGTHGQYSILQTARLLPGAPQQPPKARTGISKPYNVKQIKTTNAQEAEAAIR 1181
Query: 1172 LTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQP 1231
E++ SE + S P L+ SS P P +P P A P+ P P
Sbjct: 1182 CLLEARGGASEEAL-SAVAPRDLE-------ASSEPEPTPGAAKPETPQAPPLLPRRPPP 1233
Query: 1232 NLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKA 1291
+ +P R P E Q +T + G E+ ++ P
Sbjct: 1234 RVPAIKKPTLRRTGKPLSPEEQFEQ---QTVHFTIGPPETSVEAPP-------------V 1277
Query: 1292 QLSVQTSPVPTP---DPKRLIQLPS-----------ATQSNVLSSVSCMPTMPPIPARSQ 1337
+ + PVP P P + + PS ++V + P +P +P R +
Sbjct: 1278 VTAPRVPPVPKPRTFQPGKAAERPSHRKPASDEAPPGAGASVPPPLEAPPLVPKVPPRRK 1337
Query: 1338 SQENMRSSPNPFITGLTRTN 1357
+S+P F + ++N
Sbjct: 1338 -----KSAPAAFHLQVLQSN 1352
>gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor
[Homo sapiens]
Length = 913
Score = 211 bits (536), Expect = 6e-54
Identities = 139/420 (33%), Positives = 213/420 (50%), Gaps = 65/420 (15%)
Query: 472 DSSKQEAIDVLLLGNTLNSDLADKARALLTTGSLRASSKVLKS-MCENFYKYSKPKKIRV 530
+ SK E D++ SD A +L+ ++KS + + Y+ + R
Sbjct: 212 NKSKSEITDMVRSSTITVSDKAH----ILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRF 267
Query: 531 CVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVEL 590
GT+NVNG + L WL + GIQ D++ +GF+E+ +L
Sbjct: 268 FAGTYNVNGQSP-------KECLRLWLSN-----GIQA--------PDVYCVGFQEL-DL 306
Query: 591 NAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAV 650
+ T ++ W + + + D KY + +LVG+ L ++++ +HA +I +V
Sbjct: 307 SKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEA 366
Query: 651 DTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSF-- 708
+TV TG+ G GNKG VAIR FH TS+C V SH AA + + RN+D+ +I ++ F
Sbjct: 367 ETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQ 426
Query: 709 ------PMGRMLFSHDYVFWCGDFNYRID-LPNEEVKELIRQQNWDSLIAGDQLINQKNA 761
P+ + +HD + W GD NYRI+ L E+VK+LI ++++ L A DQL Q A
Sbjct: 427 PDPSLPPL--TISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAA 484
Query: 762 GQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDL 821
VF GF EG++TF PTYKYD SDD+DTSEKCR PAW DR+LW+ + ++
Sbjct: 485 KTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGK-----------NI 533
Query: 822 LNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVI 881
S+Q LKTSDH+PV ++ DI + V E + +E++
Sbjct: 534 TQLSYQ-----------------SHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIV 576
>gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase
isoform b [Homo sapiens]
Length = 893
Score = 206 bits (524), Expect = 1e-52
Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 56/388 (14%)
Query: 521 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 580
+Y + R VGTWNVNG + L WL P P DI+
Sbjct: 233 EYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWLNCDPN-------------PPDIY 272
Query: 581 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 640
IGF+E+ +L+ + ++ W++ +++ + KY + +LVG+ L +F R
Sbjct: 273 CIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKD 331
Query: 641 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 700
+IRD+A +TV TG+ G GNKG VA+R +FH T+ C V SH AA + RN+D+
Sbjct: 332 QCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYK 391
Query: 701 EIARKLSFPMGRM------LFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGD 753
+I ++SF + + H+ V W GD NYR+ +P+ EVK LI +++ L+ D
Sbjct: 392 DICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFD 451
Query: 754 QLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFD 813
QL Q+ + F F EG++ F PTYKYD +D +D+S KCR PAW DR+LWR
Sbjct: 452 QLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWR------- 504
Query: 814 RSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEER 873
+++ LN + ELKTSDH+PV AL I + V+
Sbjct: 505 --GTNVNQLN-------------------YRSHMELKTSDHKPVSALFHIGVKVVDERRY 543
Query: 874 QNIYKEVIAVQGPPDGTVLVSIKSSLPE 901
+ ++++ + + + L S++ S E
Sbjct: 544 RKVFEDSVRIMDRMENDFLPSLELSRRE 571
>gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase
isoform a [Homo sapiens]
Length = 901
Score = 206 bits (524), Expect = 1e-52
Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 56/388 (14%)
Query: 521 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 580
+Y + R VGTWNVNG + L WL P P DI+
Sbjct: 233 EYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWLNCDPN-------------PPDIY 272
Query: 581 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 640
IGF+E+ +L+ + ++ W++ +++ + KY + +LVG+ L +F R
Sbjct: 273 CIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKD 331
Query: 641 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 700
+IRD+A +TV TG+ G GNKG VA+R +FH T+ C V SH AA + RN+D+
Sbjct: 332 QCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYK 391
Query: 701 EIARKLSFPMGRM------LFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGD 753
+I ++SF + + H+ V W GD NYR+ +P+ EVK LI +++ L+ D
Sbjct: 392 DICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFD 451
Query: 754 QLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFD 813
QL Q+ + F F EG++ F PTYKYD +D +D+S KCR PAW DR+LWR
Sbjct: 452 QLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWR------- 504
Query: 814 RSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEER 873
+++ LN + ELKTSDH+PV AL I + V+
Sbjct: 505 --GTNVNQLN-------------------YRSHMELKTSDHKPVSALFHIGVKVVDERRY 543
Query: 874 QNIYKEVIAVQGPPDGTVLVSIKSSLPE 901
+ ++++ + + + L S++ S E
Sbjct: 544 RKVFEDSVRIMDRMENDFLPSLELSRRE 571
>gi|190014578 suppressor of actin 1 [Homo sapiens]
Length = 587
Score = 206 bits (524), Expect = 1e-52
Identities = 146/454 (32%), Positives = 237/454 (52%), Gaps = 37/454 (8%)
Query: 60 YGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLR------IDSSDE 113
+G+LG + L G+ YL+++T + VG+ V++ T + +S + D +
Sbjct: 58 FGILGTIHLVAGN----YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQ 113
Query: 114 DR---ISEVRKVLNSGNFYFAWSASGI-SLDLSLNAHRSMQEQT----TDNRFFWNQSLH 165
D ++ + VLN FYF+ + +L N QE + D RF WN L
Sbjct: 114 DNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLL 173
Query: 166 LHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDG 225
L + L ++ G + + + K LISR SC RAG R+ VRG + +G
Sbjct: 174 RELSAQP-EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEG 232
Query: 226 HVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQ-PGLQVGSHRVRMSRGFEANAPAFDR 284
H ANFVETEQ+V+ + S +SF+Q RGS+P+FW Q P L+ + + F R
Sbjct: 233 HAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKY--KPLPQISKVANHMDGFQR 290
Query: 285 HFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKA 344
HF + +YGKQ+I+NL+ K E L + F + + +S + ++ + FD+H+ K +
Sbjct: 291 HFDSQVIIYGKQVIINLINQKGSEKPLEQTFAT-MVSSLGSGMMRYIAFDFHKECKNMRW 349
Query: 345 EKLHSVLKPQVQKFLDYGFFYF--NGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEML 402
++L S+L QV + D ++ + +V Q G R+NC+DCLDRTN +Q+ L L
Sbjct: 350 DRL-SILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSL 408
Query: 403 AKQLEALG---LAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALE-------GKAKA 452
QL+ LG + +K + F++++++ W+ N ++ +K YAGTGAL+ +
Sbjct: 409 QAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHL 468
Query: 453 GKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGN 486
G + DG S+ R +NNF D +Q++ID L LGN
Sbjct: 469 GLIMDGWNSMIRYYKNNFSDGFRQDSID-LFLGN 501
>gi|7662414 inositol polyphosphate-5-phosphatase F [Homo sapiens]
Length = 1132
Score = 199 bits (507), Expect = 1e-50
Identities = 136/454 (29%), Positives = 226/454 (49%), Gaps = 55/454 (12%)
Query: 119 VRKVLNSGNFYFAWSASGISLDLSLNAHRSMQE--------QTTDNRFFWNQSLHLHLKH 170
++ ++S +FY++ ++ DL+ + R Q D+RFFWN+ + L
Sbjct: 167 LKMFMDSESFYYS-----LTYDLTNSVQRQSTGERDGRPLWQKVDDRFFWNKYMIQDLTE 221
Query: 171 YGV-NCDDWLLRLMCGGVEIRTIYA-------------------------AHKQAKACLI 204
G + D W++ ++ G V+I + H + LI
Sbjct: 222 IGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALI 281
Query: 205 SRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPGLQV 264
SR S RAG R+ RG + +G+VAN+VETEQ++++ + SF+Q RGSVP+FW Q G +
Sbjct: 282 SRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQVGYRY 341
Query: 265 GSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEH 324
+ R R+ R + F HF N+Y KQ+I+NL+ E ++ A+ + +
Sbjct: 342 -NPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNN 400
Query: 325 AADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRTNCL 384
+ + V+FD+H+ +G K E + ++ LD + + + + V Q G R NC+
Sbjct: 401 -SHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCM 459
Query: 385 DCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQ-LVTRFQEVFRSMWSVNGDSISKIYAGT 443
DCLDRTN VQA + ++ +QL+ LG+ Q L + +++ MW+ NGDSIS+ YAGT
Sbjct: 460 DCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGT 519
Query: 444 GALEG-------KAKAGKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDL---- 492
AL+G + AG +KDG S R N F D+ +Q ID L+ G + DL
Sbjct: 520 AALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVID-LMQGIPVTEDLYSIF 578
Query: 493 -ADKARALLTTGSLRASSKVLKSMCENFYKYSKP 525
+K L + R+ +++ + +++ K P
Sbjct: 579 TKEKEHEALHKENQRSHQELISQLLQSYMKLLLP 612
>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
sapiens]
Length = 1188
Score = 174 bits (440), Expect = 8e-43
Identities = 208/852 (24%), Positives = 337/852 (39%), Gaps = 136/852 (15%)
Query: 510 KVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEF 569
++L+ M + +P I + +GTWN+ + I T W L K G
Sbjct: 385 QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKI-------TSWFLS--KGQGKTRD 435
Query: 570 QDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNK--YVLLASEQ 627
P DI+ IG +E ++K W L+ ++ + +A
Sbjct: 436 DSADYIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHT 483
Query: 628 LVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAA 687
L + + V +P+H I + D VKTG+ GNKGAV + +F+ TSL FV SH +
Sbjct: 484 LWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTS 543
Query: 688 GQSQVKERNEDFIEIARKLSF---PMGRMLFSH--DYVFWCGDFNYRIDLPN---EEVKE 739
G + RN++++ I R L+ + +H ++FW GD NYR+DLP E + +
Sbjct: 544 GSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQ 603
Query: 740 LIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD-LFSDDY------DTSE 792
I+QQ + L++ DQL+ ++ +VF F E ++TFAPTY+++ L D Y T
Sbjct: 604 KIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGM 663
Query: 793 KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTS 852
K P+W DRVLW + +P + ++ S+ S I+ TS
Sbjct: 664 KYNLPSWCDRVLW--KSYPL------VHVVCQSYGSTSDIM-----------------TS 698
Query: 853 DHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDE 912
DH PV A + + + + QG + + + + F+ +
Sbjct: 699 DHSPVFATFEAGVTSQFVSKNG---PGTVDSQGQIEFLRCYATLKTKSQTKFYLE-FHSS 754
Query: 913 LLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNL 972
L+ F E E ++ V F E L + + + LL++ I I++KS D ++
Sbjct: 755 CLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESY 814
Query: 973 EE---EMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHL--QP 1027
E + LE LP T T G E+ F E + + E L + +
Sbjct: 815 GEGCIALRLEATETQLPIYTPLTHHG---ELTGHFQGEIKLQTSQGKTREKLYDFVKTER 871
Query: 1028 SSSSGLGTSPS-----------SSPRTSPCQSPTISE------------GPVPSLPIRPS 1064
SSG T S + R PC +I+E GP L ++ +
Sbjct: 872 DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
Query: 1065 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP 1124
+P + P S P D+ P P + PP P P PP +P + P
Sbjct: 932 LSPDQQPTAWSYDQPPKDS----------PLGPCRGESPPTP-PGQPPI--SPKKFLPST 978
Query: 1125 SGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETS 1184
+ R P P+ + P G A T+P ++ P+ G L+
Sbjct: 979 ANRGLP-PRTQESRPSDLG-KNAGDTLPQEDLPLTKPEMFENPLYGSLS----------- 1025
Query: 1185 KGSTFLPEPLKPQAAFPPQSSLPPPAQR---LQEPLVPVAAPMPQSGPQPNLETPPQPPP 1241
S P P K Q + PPP L +V A G P + P P
Sbjct: 1026 --SFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQV---PAP 1080
Query: 1242 RSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVP 1301
R R S +S++ + S GK ++P+ + S+++++ QT P P
Sbjct: 1081 RLR---SFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAK-RPIKPSRSEINQQTPPTP 1136
Query: 1302 TPDPKRLIQLPS 1313
TP P ++ P+
Sbjct: 1137 TPRPPLPVKSPA 1148
Score = 36.6 bits (83), Expect = 0.19
Identities = 30/105 (28%), Positives = 44/105 (41%), Gaps = 12/105 (11%)
Query: 1029 SSSGLGTSPSSSPRTSPCQSPTISEGPVPSL-PIRPSRAPSRTPGPPSAQSSPIDAQPAT 1087
SSS G + ++P S+ PVP+ PI+PSR+ PP+ P
Sbjct: 1088 SSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRP------- 1140
Query: 1088 PLPQKDPA----QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRS 1128
PLP K PA Q + + + + P + PP P GR+
Sbjct: 1141 PLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRT 1185
>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
sapiens]
Length = 1189
Score = 174 bits (440), Expect = 8e-43
Identities = 208/852 (24%), Positives = 337/852 (39%), Gaps = 136/852 (15%)
Query: 510 KVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEF 569
++L+ M + +P I + +GTWN+ + I T W L K G
Sbjct: 386 QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKI-------TSWFLS--KGQGKTRD 436
Query: 570 QDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNK--YVLLASEQ 627
P DI+ IG +E ++K W L+ ++ + +A
Sbjct: 437 DSADYIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHT 484
Query: 628 LVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAA 687
L + + V +P+H I + D VKTG+ GNKGAV + +F+ TSL FV SH +
Sbjct: 485 LWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTS 544
Query: 688 GQSQVKERNEDFIEIARKLSF---PMGRMLFSH--DYVFWCGDFNYRIDLPN---EEVKE 739
G + RN++++ I R L+ + +H ++FW GD NYR+DLP E + +
Sbjct: 545 GSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQ 604
Query: 740 LIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD-LFSDDY------DTSE 792
I+QQ + L++ DQL+ ++ +VF F E ++TFAPTY+++ L D Y T
Sbjct: 605 KIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGM 664
Query: 793 KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTS 852
K P+W DRVLW + +P + ++ S+ S I+ TS
Sbjct: 665 KYNLPSWCDRVLW--KSYPL------VHVVCQSYGSTSDIM-----------------TS 699
Query: 853 DHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDE 912
DH PV A + + + + QG + + + + F+ +
Sbjct: 700 DHSPVFATFEAGVTSQFVSKNG---PGTVDSQGQIEFLRCYATLKTKSQTKFYLE-FHSS 755
Query: 913 LLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNL 972
L+ F E E ++ V F E L + + + LL++ I I++KS D ++
Sbjct: 756 CLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESY 815
Query: 973 EE---EMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHL--QP 1027
E + LE LP T T G E+ F E + + E L + +
Sbjct: 816 GEGCIALRLEATETQLPIYTPLTHHG---ELTGHFQGEIKLQTSQGKTREKLYDFVKTER 872
Query: 1028 SSSSGLGTSPS-----------SSPRTSPCQSPTISE------------GPVPSLPIRPS 1064
SSG T S + R PC +I+E GP L ++ +
Sbjct: 873 DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 932
Query: 1065 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP 1124
+P + P S P D+ P P + PP P P PP +P + P
Sbjct: 933 LSPDQQPTAWSYDQPPKDS----------PLGPCRGESPPTP-PGQPPI--SPKKFLPST 979
Query: 1125 SGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETS 1184
+ R P P+ + P G A T+P ++ P+ G L+
Sbjct: 980 ANRGLP-PRTQESRPSDLG-KNAGDTLPQEDLPLTKPEMFENPLYGSLS----------- 1026
Query: 1185 KGSTFLPEPLKPQAAFPPQSSLPPPAQR---LQEPLVPVAAPMPQSGPQPNLETPPQPPP 1241
S P P K Q + PPP L +V A G P + P P
Sbjct: 1027 --SFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQV---PAP 1081
Query: 1242 RSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVP 1301
R R S +S++ + S GK ++P+ + S+++++ QT P P
Sbjct: 1082 RLR---SFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAK-RPIKPSRSEINQQTPPTP 1137
Query: 1302 TPDPKRLIQLPS 1313
TP P ++ P+
Sbjct: 1138 TPRPPLPVKSPA 1149
Score = 36.6 bits (83), Expect = 0.19
Identities = 30/105 (28%), Positives = 44/105 (41%), Gaps = 12/105 (11%)
Query: 1029 SSSGLGTSPSSSPRTSPCQSPTISEGPVPSL-PIRPSRAPSRTPGPPSAQSSPIDAQPAT 1087
SSS G + ++P S+ PVP+ PI+PSR+ PP+ P
Sbjct: 1089 SSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRP------- 1141
Query: 1088 PLPQKDPA----QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRS 1128
PLP K PA Q + + + + P + PP P GR+
Sbjct: 1142 PLPVKSPAVLHLQHSKGRDYRDNTELPHHGKHRPEEGPPGPLGRT 1186
>gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A
[Homo sapiens]
Length = 638
Score = 160 bits (404), Expect = 1e-38
Identities = 179/672 (26%), Positives = 278/672 (41%), Gaps = 107/672 (15%)
Query: 525 PKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGF 584
P + R+ V TWNV A +T L L G + S D+ AIG
Sbjct: 52 PSEPRITVVTWNVG-------TAMPPDDVTSLL----HLGGGDD-----SDGADMIAIGL 95
Query: 585 EEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPF 644
+E+ + + A T+Q W+ + N +VL++S ++ GV L +F + H PF
Sbjct: 96 QEVNSMLNKRLKDALFTDQ--WSELFMDALGPFN-FVLVSSVRMQGVILLLFAKYYHLPF 152
Query: 645 IRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIAR 704
+RDV D +TG+GG GNKG V++R+ LCF+ H A + ++R ++F I
Sbjct: 153 LRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILS 212
Query: 705 KLSF--PMGRMLFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGDQLINQKNA 761
F P + + HD VFW GD N+RI+ + VK I L DQL KN
Sbjct: 213 LQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNT 272
Query: 762 GQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRR-----KWPFDRSA 816
+ +GF EG + FAPT+K+D+ ++ YDTS K R PAWTDR+LW+ + P R +
Sbjct: 273 WPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKS 332
Query: 817 EDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVA--LIDIDIFEVEAEERQ 874
L + S++ E SDH+PV A L+ + R
Sbjct: 333 HRLQVTQHSYR-----------------SHMEYTVSDHKPVAAQFLLQFAFRDDMPLVRL 375
Query: 875 NIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMW 934
+ E + P V +++ +++ L + + + + ED
Sbjct: 376 EVADEWVR---PEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKH-EDVDG 431
Query: 935 VTFLEGSSALNVLSLNGKELL-----NRTITIALKSPDWIKNLEEEMSLEKISIALPSST 989
T+ S ++ +G +L N +I I + P I+LPSS
Sbjct: 432 NTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEP--------------FQISLPSSE 477
Query: 990 SSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSP 1049
L + ++ EG+ DD + E+ L P S S SP S R +SP
Sbjct: 478 ----LASSSTDSSGTSSEGE-DDSTLEL-------LAPKSRS---PSPGKSKR-HRSRSP 521
Query: 1050 TISEGPVPSLPIRPS----RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPP 1105
++ P L +RPS R SR+P P S + S + ++ + ++
Sbjct: 522 GLAR--FPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEE-------- 571
Query: 1106 PRPVAPPTRPAPPQRPP--PPSGRSQPSPQAGLAGPGPAG-YSTARPTIPPRAGVISAPQ 1162
P P P PP P S P+ + PG G + R + P + + +PQ
Sbjct: 572 ----GPSGLPGPWAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNS-LSPSPQ 626
Query: 1163 SHARASAGRLTP 1174
H G L P
Sbjct: 627 GHRGLEEGGLGP 638
>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens]
Length = 1258
Score = 157 bits (396), Expect = 1e-37
Identities = 200/789 (25%), Positives = 316/789 (40%), Gaps = 136/789 (17%)
Query: 507 ASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGI 566
A ++L+ M K +P I V +GTWN+ +++ T W G+
Sbjct: 403 AFCQLLQLMKNKHSKQDEPDMISVFIGTWNMGSVPPPKNV-------TSWFTSK----GL 451
Query: 567 QEFQDKRSK--PTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR--DNKYVL 622
+ D+ + P DI+ G +E ++ + W L+ + D Y
Sbjct: 452 GKTLDEVTVTIPHDIYVFGTQE------------NSVGDREWLDLLRGGLKELTDLDYRP 499
Query: 623 LASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVC 682
+A + L + + V ++P+H I V+ +VKTG+ GNKGAV + +F+ TS FV
Sbjct: 500 IAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVN 559
Query: 683 SHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHD------YVFWCGDFNYRIDLPNEE 736
H +G + RN+++++I R LS R L + D ++FW GD NYR+D+ +E
Sbjct: 560 CHLTSGNEKTARRNQNYLDILRLLSLG-DRQLNAFDISLRFTHLFWFGDLNYRLDMDIQE 618
Query: 737 VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDD-------YD 789
+ I ++ ++ L+ DQL ++ +VF F E +++F PTY+Y+ S D
Sbjct: 619 ILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQKP 678
Query: 790 TSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASF--------QDESKILYTWTPGTL 841
T + P+W DR+LW +S + ++ S+ D S + T+ G
Sbjct: 679 TGVRTNVPSWCDRILW--------KSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVGVT 730
Query: 842 LHY--GRAELKTSDHRPVVALIDIDIFE--VEAEERQNIYKEVIAVQGPPDGTVLVSIKS 897
+ + KTSD A I+ + E V+ R + E + T L K
Sbjct: 731 SQFISKKGLSKTSDQ----AYIEFESIEAIVKTASRTKFFIEFYS-------TCLEEYKK 779
Query: 898 SLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSS-ALNVLSLNGKELLN 956
S EN+ I+ L Q++S L + D + +L+ L V S++G E
Sbjct: 780 SF-ENDAQSSDNINFLKVQWSSRQLPTLKPILAD---IEYLQDQHLLLTVKSMDGYESYG 835
Query: 957 RTITIALKSP---------DWIKNLEEEMS--LEKISIALPSSTSSTLLGEDAEVAADFD 1005
+ +ALKS ++ + EE + + +P+ T
Sbjct: 836 ECV-VALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGT------------- 881
Query: 1006 MEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG--PVPSLPIRP 1063
E + S + +E + PS S G S PR S + P +E P+ L P
Sbjct: 882 RERLYEWISIDKDEAGAKSKAPSVSRG-----SQEPR-SGSRKPAFTEASCPLSRLFEEP 935
Query: 1064 SRAP--SRTPGPPSAQSSPIDAQPATPLPQKDPAQP-LEPKRPPPPRPVAPPTRPAPPQR 1120
+ P R P PP A P+++P P L+P+ P P VA P
Sbjct: 936 EKPPPTGRPPAPPRA------------APREEPLTPRLKPEGAPEPEGVAAPPPKNSFNN 983
Query: 1121 PPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQ----SHARASAGRLTPES 1176
P P P PA T A + APQ H R G S
Sbjct: 984 PAYYVLEGVPHQLLPPEPPSPARAPVPSATKNKVAITVPAPQLGHHRHPRVGEG---SSS 1040
Query: 1177 QSKTSETSKGSTFLPEPLKPQAAFPPQS--SLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1234
++ T F P PL A F P S LP P R + P P++ P+P L
Sbjct: 1041 DEESGGTLPPPDFPPPPLPDSAIFLPPSLDPLPGPVVRGRGGAEARGPPPPKAHPRPPL- 1099
Query: 1235 TPPQPPPRS 1243
PP P P S
Sbjct: 1100 -PPGPSPAS 1107
Score = 33.9 bits (76), Expect = 1.2
Identities = 65/233 (27%), Positives = 80/233 (34%), Gaps = 50/233 (21%)
Query: 1017 VEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA 1076
V E +P L P SP+ +P S ++ P P L R P G S
Sbjct: 988 VLEGVPHQLLPPEPP----SPARAPVPSATKNKVAITVPAPQLGHH--RHPRVGEGSSSD 1041
Query: 1077 QSS----PIDAQPATPLPQKDPAQPLEPKRPPPPRPV------APPTRPAPPQRPPPPSG 1126
+ S P P PLP D A L P P P PV A P PP+ P P
Sbjct: 1042 EESGGTLPPPDFPPPPLP--DSAIFLPPSLDPLPGPVVRGRGGAEARGPPPPKAHPRPPL 1099
Query: 1127 RSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKG 1186
PSP + G +G + S Q S P ++
Sbjct: 1100 PPGPSPASTFLGEVASGDDRS----------CSVLQMAKTLSEVDYAPAGPAR------- 1142
Query: 1187 STFLPEPLKPQAAFPPQS---------SLPPPAQR--LQEPLVPVAAPMPQSG 1228
S LP PL+ Q PP+ S PPP R +QE L AP Q G
Sbjct: 1143 SALLPGPLELQ---PPRGLPSDYGRPLSFPPPRIRESIQEDLAE-EAPCLQGG 1191
>gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]
Length = 644
Score = 139 bits (351), Expect = 2e-32
Identities = 110/378 (29%), Positives = 168/378 (44%), Gaps = 73/378 (19%)
Query: 503 GSLRASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPK 562
GSL AS +L + + +Y + + + V TWN+ G K+ +L ++LL A
Sbjct: 276 GSLLASGALLGA--DELARYFPDRNVALFVATWNMQGQKELPP------SLDEFLLPA-- 325
Query: 563 LAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVL 622
+ D++ IG +E ++++ W LQ+T+ YVL
Sbjct: 326 ---------EADYAQDLYVIGVQE------------GCSDRREWETRLQETLGPH--YVL 362
Query: 623 LASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVC 682
L+S + + +FIR F +V TV T + KGA+ I F TS F+
Sbjct: 363 LSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFIT 422
Query: 683 SHFAAGQSQVKERNEDFIEIARKLSFPMG------------RMLFSHDYVFWCGDFNYRI 730
SHF +G +V ER D+ + L P + D VFW GDFN+R+
Sbjct: 423 SHFTSGDGKVAERLLDYTRTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRL 482
Query: 731 DLPNEEVKELIRQQ---NWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDD 787
V L+ Q + +L+ DQLI + G +F+GF E + F P+YK+D+ D
Sbjct: 483 SGGRTVVDALLCQGLVVDVPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDT 542
Query: 788 YDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRA 847
YD++ K RTP++TDRVL+R R D + Y+ PG
Sbjct: 543 YDSTSKQRTPSYTDRVLYRSR----------------HKGDICPVSYSSCPG-------- 578
Query: 848 ELKTSDHRPVVALIDIDI 865
+KTSDHRPV L + +
Sbjct: 579 -IKTSDHRPVYGLFRVKV 595
Score = 39.7 bits (91), Expect = 0.023
Identities = 48/195 (24%), Positives = 76/195 (38%), Gaps = 26/195 (13%)
Query: 1039 SSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQ-PATPLPQKDPAQ- 1096
S P P + T+ +G +P P P++ P P ++S + PATP + PA+
Sbjct: 11 SEPAPQPPEGRTL-QGQLPGAP--PAQRAGSPPDAPGSESPALACSTPATPSGEDPPARA 67
Query: 1097 -PLEPKRPPPPRPVAPPTRPAPPQRPPPPSG-------RSQPSPQAGLA---GPG----- 1140
P+ P+ P PR + R G R+ SP G GPG
Sbjct: 68 APIAPRPPARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTSPSRGSVQSEGPGAPAHS 127
Query: 1141 --PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQA 1198
P ST+ IP GV+S+ + + L+ + S + + + + +
Sbjct: 128 CSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSSPRLPS 187
Query: 1199 AFPPQSSLPPPAQRL 1213
PP+ PPPA L
Sbjct: 188 LLPPR---PPPALSL 199
Score = 35.8 bits (81), Expect = 0.33
Identities = 50/197 (25%), Positives = 70/197 (35%), Gaps = 49/197 (24%)
Query: 1084 QPATPLPQKDPAQPLE---PKRPPPPRPVAPPTRPAPP------QRPPPPSGRSQPSPQA 1134
+P+ P PQ + L+ P PP R +PP P P PSG P+ A
Sbjct: 9 RPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
Query: 1135 GLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPL 1194
+A P ARP + + R + E+++ TS S+GS P
Sbjct: 69 PIAPRPP-----ARPRLERALSLDDKGWRRRRFRGSQEDLEARNGTS-PSRGSVQSEGPG 122
Query: 1195 KPQAAFPPQSSLPPPAQRLQE--------------------PLVPVAAPMPQ-------- 1226
P + P P + LQE PL VA+ P
Sbjct: 123 APAHSCSP----PCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAV 178
Query: 1227 SGPQPNLET--PPQPPP 1241
+G P L + PP+PPP
Sbjct: 179 AGSSPRLPSLLPPRPPP 195
>gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo
sapiens]
Length = 448
Score = 133 bits (335), Expect = 1e-30
Identities = 98/301 (32%), Positives = 153/301 (50%), Gaps = 23/301 (7%)
Query: 571 DKRSKPTDIFAIGFEEMVELNAG--NIVSASTTNQKLWAVELQKTISRDNKYVLLASEQL 628
+ R+ DI+ IG +E LN+G +++S + N W+ L +S ++ ++ ++
Sbjct: 39 NNRNLNLDIYVIGLQE---LNSGIISLLSDAAFNDS-WSSFLMDVLS-PLSFIKVSHVRM 93
Query: 629 VGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAG 688
G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + + + H
Sbjct: 94 QGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPH 153
Query: 689 QSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNEEVKELIRQQ 744
S +R E F I + GR + HD + W GD N+RI D V+E I+ +
Sbjct: 154 ISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNR 212
Query: 745 NWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVL 804
+ L DQL K + R F EG++ F PTYK+D S+DYDTSEK R PAWTDR+L
Sbjct: 213 CYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRIL 272
Query: 805 WRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDID 864
WR ++ P + D + AS S Y+ + + YG SDH+PV D++
Sbjct: 273 WRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHKPVSGTFDLE 321
Query: 865 I 865
+
Sbjct: 322 L 322
>gi|7662034 Sac domain-containing inositol phosphatase 3 [Homo
sapiens]
Length = 907
Score = 132 bits (332), Expect = 3e-30
Identities = 141/520 (27%), Positives = 230/520 (44%), Gaps = 103/520 (19%)
Query: 55 KVLDAYGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFI-----SLRID 109
+ + A+G++G +R G +Y+VL+T + I +++V T I S+R+
Sbjct: 88 RAVSAFGVVGFVRFLEG----YYIVLITKRRKMADIGGHAIYKVEDTNMIYIPNDSVRVT 143
Query: 110 SSDEDRISEV-RKVLNSGNFYFAWSAS-GISLDLSLNAHRS----MQEQTTDNR------ 157
DE R + + V S NFYF++S SL +L R ++ + T NR
Sbjct: 144 HPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMTQNRQESFDI 203
Query: 158 ------------------------FFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIY 193
+ WN L +K DWLL ++ G +
Sbjct: 204 FEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIK--STVHRDWLLYIIHGFCGQSKLL 261
Query: 194 AAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVV-------YLDDSVSSF 246
+ LI+R S + AGTRF RG N +G VAN VETEQ++ + S SS+
Sbjct: 262 IYGRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSY 321
Query: 247 IQIRGSVPLFWEQP-GLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIV-NLLGS 304
+Q+RGSVPL+W Q + + + + + A HF + +G II+ NL+
Sbjct: 322 VQVRGSVPLYWSQDISTMMPKPPITLDQA-DPFAHVAALHFDQMFQRFGSPIIILNLVKE 380
Query: 305 KEG---EHMLSK------AFQSHLKASEHAADIQMVNFDYHQMVKG---GKAEKLHSVLK 352
+E E +LS+ + + EH I + +D + K ++L+ + +
Sbjct: 381 REKRKHERILSEELVAAVTYLNQFLPPEHT--IVYIPWDMAKYTKSKLCNVLDRLNVIAE 438
Query: 353 PQVQKFLDYGFFY------------------FNGSEVQ--RCQSGTVRTNCLDCLDRTNS 392
V+K GFF G + R Q+G +RTNC+DCLDRTN+
Sbjct: 439 SVVKKT---GFFVNRPDSYCSILRPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNT 495
Query: 393 VQAFLGLEMLAKQLEALGLAEKP--QLVTRFQEVFRSMWSVNGDSISKIYAGTGALEGKA 450
Q +G LA QL +LGL +KP Q T +F ++ +GD++S Y G+ +
Sbjct: 496 AQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVK 555
Query: 451 KAGKL-------KDGARSVTRTIQNNFFDSSKQEAIDVLL 483
K+ KD ++++R N F D+ +Q++I++ L
Sbjct: 556 TYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFL 595
>gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 125 bits (314), Expect = 3e-28
Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%)
Query: 620 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 679
++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + +
Sbjct: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68
Query: 680 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 735
+ H S +R E F I + GR + HD + W GD N+RI D
Sbjct: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127
Query: 736 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 795
V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R
Sbjct: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187
Query: 796 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 855
PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+
Sbjct: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236
Query: 856 PVVALIDIDI 865
PV D+++
Sbjct: 237 PVSGTFDLEL 246
>gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 125 bits (314), Expect = 3e-28
Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%)
Query: 620 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 679
++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + +
Sbjct: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68
Query: 680 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 735
+ H S +R E F I + GR + HD + W GD N+RI D
Sbjct: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127
Query: 736 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 795
V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R
Sbjct: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187
Query: 796 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 855
PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+
Sbjct: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236
Query: 856 PVVALIDIDI 865
PV D+++
Sbjct: 237 PVSGTFDLEL 246
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 96.7 bits (239), Expect = 2e-19
Identities = 141/511 (27%), Positives = 191/511 (37%), Gaps = 110/511 (21%)
Query: 1020 LLPQHLQPSSSSGLGTSPSSSPR--TSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1077
L P LQ +S+ P ++P T PC +P + P L P PS PP Q
Sbjct: 541 LAPPPLQTASA------PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP-PQ 593
Query: 1078 SSPIDAQPATPLPQKDPAQPLEPKRPPPPR---PVAPPTRPAPPQRP--PPPSGRSQPSP 1132
+ P A P PL Q P+ PL P PPP+ +A P APP P PP S + PSP
Sbjct: 594 APPALASP--PL-QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650
Query: 1133 QAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS--AGRLTPESQSKTSETSKGSTFL 1190
QA A A + P PP + + AP S + + TP SQ+ S +
Sbjct: 651 QAPNA---LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707
Query: 1191 PE-----PLKPQAAFPPQSSLP--------PPAQRLQEPLVPVAAPMPQSGP---QPNLE 1234
P P+ P A PPQ+ P PP+ P+ P A P P+ P P L+
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767
Query: 1235 TPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLS 1294
PP PP SLP ++P + PL+ P SF A S
Sbjct: 768 VPPSPPA------SLPMSPLAKPPPQA---PPALATPPLQALPSPPASFPGQAPFSPSAS 818
Query: 1295 VQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLT 1354
+ SP+ TP P Q P + +L +PP P S + + R P P +
Sbjct: 819 LPMSPLATPPP----QAPPVLAAPLLQ-------VPPSPPASPTLQAPRRPPTPG-PDTS 866
Query: 1355 RTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGF 1414
+ P APG P P PS P SS+L G
Sbjct: 867 VSGPRLTLALAPGPP-----------------------PPPSRSP--------SSTLSG- 894
Query: 1415 KDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDD 1474
DL G S+ S P+ ++ + G S ++L P++
Sbjct: 895 ---PDLAGHSSSATSTPEELRGYDSGPEGGA-AASPPPDAELAACHPAA----------- 939
Query: 1475 WNKGTNVSFCVLPSRRPPPPPVPLLPPGTSP 1505
W++G L R P P+P PP T P
Sbjct: 940 WSRGPAPP---LAFRGAPGAPLP-WPPATGP 966
Score = 84.7 bits (208), Expect = 6e-16
Identities = 149/546 (27%), Positives = 192/546 (35%), Gaps = 123/546 (22%)
Query: 1026 QPSSSSGL------GTSPSSSPRTSPCQSPTISEGPVPSLPIRPS----------RAPSR 1069
+PS+ GL S S++P +SP +S + G P P PS R P
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG-TPRAPAHPSQPKPKGLQALRPPQV 285
Query: 1070 TPGPPSAQSS--PIDAQP-ATPLPQKDPAQPLEPKRP---------PPPRPVAPPTRPAP 1117
TP A + P+ + P ATP P A+P+ P PP P+A P AP
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
Query: 1118 PQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQ-SHARASAGRLTPES 1176
P PPS ++ PSP A P +T PP I Q H+ S P S
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405
Query: 1177 ----QSKTSETSKGSTFLP--------EPLKPQAAFPPQS---SLPPPAQRLQEPLVPVA 1221
S + TS GS L P + QA+ S S PP + LQ PL A
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465
Query: 1222 APMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDL 1281
+P Q+ P + +P P +L S AS PQ S L + P E
Sbjct: 466 SPPLQTSLSPAV-SPLSSPLTIHPLQALSSLASHSPQAPL---------SSLIMPPLETQ 515
Query: 1282 SFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPT----MPPIPARSQ 1337
S S A S+QT P P L LPS + ++ + + T PP PA
Sbjct: 516 S------SLAPPSLQTPPASLTTPP-LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
Query: 1338 SQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSL 1397
+++ P+P T T P S T P P S P+ P P L
Sbjct: 569 ----LQAPPSPLTTPPPET-PSSIATPPPQAPPALAS------------PPLQGLPSPPL 611
Query: 1398 QPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLL 1457
PL +A L LQ + S P S L
Sbjct: 612 SPLATPPPQAPPXL----ALPPLQAPPSPPASPP---------------------LSPLA 646
Query: 1458 GNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPV--PLLPPGTSPPVDPFTTLAS 1515
P + V P PP PPV P PP SPPV P T S
Sbjct: 647 TPSPQA------------PNALAVHLLQAPFSPPPSPPVQAPFSPP-ASPPVSPSATPPS 693
Query: 1516 KASPTL 1521
+A P+L
Sbjct: 694 QAPPSL 699
Score = 80.5 bits (197), Expect = 1e-14
Identities = 90/343 (26%), Positives = 135/343 (39%), Gaps = 28/343 (8%)
Query: 1025 LQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP-SLPIRPSRAPSRTPGPPSAQSSP--- 1080
L P SSS L T S + P P + P+P +LP P A PPS + P
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355
Query: 1081 -IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGP 1139
+ + PATP Q P+ P + PP PP + P PS ++ PSP A
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ--VPHSLTSPSLQAPPSPLA--LSS 411
Query: 1140 GPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAA 1199
A S PT+ ++ +AS S S+ + T S L PL A+
Sbjct: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASL-----TSPSRPASTPPDSPPLQAPLSLPAS 466
Query: 1200 FPPQSSLPPPAQRLQEPL----VPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASS 1255
P Q+SL P L PL + + + PQ L + PP ++SS + PS +
Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526
Query: 1256 QPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSAT 1315
+ T + + +P P + S L ++T P P P P L PS
Sbjct: 527 PASLTTPPLENLPSLAP---PPLQTASAPLTTP-----HLETPPCPAPCP--LQAPPSPL 576
Query: 1316 QSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNP 1358
+ + S + T PP + + ++ P+P ++ L P
Sbjct: 577 TTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619
Score = 80.1 bits (196), Expect = 2e-14
Identities = 102/348 (29%), Positives = 132/348 (37%), Gaps = 81/348 (23%)
Query: 1014 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGP 1073
S + L HL + S + P +P SP SP +S P PS A P
Sbjct: 649 SPQAPNALAVHLLQAPFSPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707
Query: 1074 PSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPA--PPQRPPP----PSGR 1127
PS +SP + ATP PQ P P + PP P +PP P+ PP R PP P +
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767
Query: 1128 SQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGS 1187
PSP A L A+P PP+A A TP Q+ S
Sbjct: 768 VPPSPPASLPMS-----PLAKP--PPQAPPALA------------TPPLQALPS------ 802
Query: 1188 TFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGP---QPNLETPPQPPPRSR 1244
P A+FP Q+ P A P+ P+A P PQ+ P P L+ PP PP
Sbjct: 803 --------PPASFPGQAPFSPSASL---PMSPLATPPPQAPPVLAAPLLQVPPSPPA--- 848
Query: 1245 SSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPD 1304
S +A +P P D S VS +L++ +P P P
Sbjct: 849 ---SPTLQAPRRPPT-----------------PGPDTS-----VSGPRLTLALAPGPPPP 883
Query: 1305 PKRLIQLPSATQSNV-LSSVSCMPTMPPIPAR---SQSQENMRSSPNP 1348
P R PS+T S L+ S T P R S + +SP P
Sbjct: 884 PSR---SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 928
Score = 70.1 bits (170), Expect = 2e-11
Identities = 114/460 (24%), Positives = 165/460 (35%), Gaps = 83/460 (18%)
Query: 1032 GLGTSPSSSPRTSPCQSP-TISEGPVPSLPI--RPSRAP---SRTPGPPSAQSSPIDAQP 1085
G T P S+PR P +S T S P P R RAP + +PGP S+
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
Query: 1086 ATPLPQKDPAQPLE-----------PKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQA 1134
PL QK E PKR T P P P R +
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
Query: 1135 GLAGPGPAGYSTAR-PTIPPRAGVISA---------PQSHARASAG-------------R 1171
+ P PA + R PT PR V SA P + R SAG
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 1172 LTP-ESQSKTSETSKGSTFLP-EPLKP-----QAAFPPQSSLPPPAQRLQEPLVPVAAPM 1224
TP S +++ +++G+ P P +P QA PPQ + PP + L P+++
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ--VTPPRKDAAPALGPLSS-S 302
Query: 1225 PQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFN 1284
P + P P+ PP ++ LP+ P + T PL + P
Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLAT----------PLPLAP------- 345
Query: 1285 LLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPA-RSQSQENMR 1343
A S+QT P P P Q P + + + + + T+PPI S + +++
Sbjct: 346 --PSPSAPPSLQTLPSPPATPPS--QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401
Query: 1344 SSPNPF-ITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISP--------- 1393
+ P+P ++ L T T + F S S S P + P
Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461
Query: 1394 -FPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPK 1432
P+ PL + S A S L LQ S+L +P+
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501
Score = 48.5 bits (114), Expect = 5e-05
Identities = 86/364 (23%), Positives = 124/364 (34%), Gaps = 81/364 (22%)
Query: 1064 SRAPSR-TPGPPSAQSSPIDAQPAT-----------PLPQKDPAQPLEPKRPPPPRPVAP 1111
+RAP TP PP + P PA P + A + P P A
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 1112 PTRPA------PPQRPP--------PPSGRSQPSP------QAGLAGPGPAGYSTARPTI 1151
PTR A P RPP PP+ + P P +G PGP G R
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR--- 135
Query: 1152 PPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ 1211
ISA ++ AR A +S S ++ T P P P A +S
Sbjct: 136 ------ISAEETVARGKA--TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 1212 RLQEPLVPVAAPMPQS-GPQPNLE-------TPPQPPPRSRSS--HSLPSEASSQPQVKT 1261
L P P A P P + GP+ ++ T P P R R S L AS
Sbjct: 188 GLPRP-APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
Query: 1262 NGISDGKRESP-------LKIDPFEDLSFNLLAVSKAQLS------------VQTSPVPT 1302
+S R P P + L A+ Q++ + +SP+ T
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
Query: 1303 PDPKRLIQLPSATQSNVLSSV-SCMPTMPPI-------PARSQSQENMRSSPNPFITGLT 1354
P P P N + + + +P PP+ P + ++++ P+P T +
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366
Query: 1355 RTNP 1358
+ P
Sbjct: 367 QAPP 370
Score = 35.0 bits (79), Expect = 0.56
Identities = 33/112 (29%), Positives = 40/112 (35%), Gaps = 2/112 (1%)
Query: 1037 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRT-PGPPSAQSSPIDAQPATPLPQKDPA 1095
P+ P TS P ++ P P PSR+PS T GP A S L D
Sbjct: 859 PTPGPDTS-VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 917
Query: 1096 QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTA 1147
PPP PA R P P + +P A L P G +A
Sbjct: 918 PEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 969
Score = 34.3 bits (77), Expect = 0.95
Identities = 73/309 (23%), Positives = 110/309 (35%), Gaps = 53/309 (17%)
Query: 1091 QKDPAQPLEPKRPPPPR-PVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARP 1149
++D A+ R P R P RP RPPP P A L G AG + R
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPP------PVTPAALRVLGAAG-AVGRK 56
Query: 1150 TIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQS---SL 1206
+ RAG I G PES + T T P A+ PP S
Sbjct: 57 PLAERAGGI----------GGATIPESAPRAGPTRSAGTSSRNP----ASRPPASGRGER 102
Query: 1207 PPPAQRLQEPLVPVAAPMPQSG---PQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNG 1263
PPA+ PV++P SG P P + + + +EA + +
Sbjct: 103 APPAKNTSPG--PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160
Query: 1264 ISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTS-PVPTPDPKRLIQLPSATQSNVLSS 1322
D +P P A+++ + T +P P P + P+ +SS
Sbjct: 161 RRDTSGPTPGTPSP---------AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 211
Query: 1323 VSCMPTMPPIPA-----------RSQSQENMRSSPNPFITGLTRTNPFSDRT-AAPGNPF 1370
S T P PA + + ++ SS P ++ R+ P + T AP +P
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP-LSSPARSGPSARGTPRAPAHPS 270
Query: 1371 RAKSEESEA 1379
+ K + +A
Sbjct: 271 QPKPKGLQA 279
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 94.4 bits (233), Expect = 8e-19
Identities = 96/398 (24%), Positives = 143/398 (35%), Gaps = 30/398 (7%)
Query: 1012 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1071
DY V P ++ S T+PS P ++ PT + P + P P+ TP
Sbjct: 1381 DYKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPP--PTTTP 1438
Query: 1072 GPP--SAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPP---QRPPPPSG 1126
PP + + P P+ P+ P PP P P T P+PP PPP+
Sbjct: 1439 SPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPT- 1497
Query: 1127 RSQPSPQAGLAGPGPAGYSTARPTIPPR--AGVISAPQSHARASAGRLTPESQSKTSETS 1184
+ PSP PA +T PT P + P S TP + TS T+
Sbjct: 1498 -TTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT-PPTSTTT 1555
Query: 1185 KGSTFLPEPLKPQAAFPPQSSLPPPAQRL--QEPLVPVAAPMPQSGPQPNLETPPQPPPR 1242
T P P PP ++ P P P + P P + P P T PPP
Sbjct: 1556 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP- 1614
Query: 1243 SRSSHSLPSEASSQPQVKTNGISDGKRESP-----LKIDPFEDLSFNLLAVSKAQLSVQT 1297
++ S P+ P T + SP P S ++ T
Sbjct: 1615 -TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673
Query: 1298 SPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTN 1357
+P PT P I + + +++ S T P P + + + ++P+P T +T +
Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTTMTTPS-PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS 1732
Query: 1358 PFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFP 1395
P T P P + T+ P+T +P P
Sbjct: 1733 P----TTTPSPPTTTMTTLPPTTT----SSPLTTTPLP 1762
Score = 78.6 bits (192), Expect = 4e-14
Identities = 89/360 (24%), Positives = 121/360 (33%), Gaps = 50/360 (13%)
Query: 1070 TPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPR-----PVAPPTRPAPPQRPPPP 1124
TP PP+ SP T P P+ P PPP P+ T P P P PP
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457
Query: 1125 SG--------------RSQPSPQAGLAGPGPAGYSTARPTI---PPRAGVISAPQSHARA 1167
+ PSP P +T PT PP I+ P S
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS--TT 1515
Query: 1168 SAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP-PPAQRLQEPLVPVAAPMPQ 1226
+ T S T+ T+ T P P PP S+ PP P P P
Sbjct: 1516 TLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1575
Query: 1227 SGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLL 1286
+ P P T P PP + ++ P+ S P T SP P
Sbjct: 1576 TTPSPPTTTTPSPPTITTTTPP-PTTTPSPPTTTTTTPPPTTTPSPPTTTPITP------ 1628
Query: 1287 AVSKAQLSVQTSPVP------TPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQE 1340
S L T+P P TP P P+ T + ++ T PP S
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS--PPITTTTTPPPTTTPSSP-- 1684
Query: 1341 NMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTI-SPFPSLQP 1399
+ ++P+P T +T +P T P +P + S T+ P T+ +P P+ P
Sbjct: 1685 -ITTTPSPPTTTMTTPSP----TTTPSSPITTTTTPSSTTT--PSPPPTTMTTPSPTTTP 1737
Score = 50.4 bits (119), Expect = 1e-05
Identities = 64/296 (21%), Positives = 104/296 (35%), Gaps = 51/296 (17%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 4052 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 4108
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 4109 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 4165
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + + P + + T+ ++ +T P P
Sbjct: 4166 TPTGTQTPTTTPITTTTTVTPTPTPTGT-QTGPPTHTSTAPIAELTTSNP---------P 4215
Query: 1202 PQSSLPPPAQRLQEPL---------VPVAAPMPQSGPQPNLETPPQPPPRSRSSHSL--- 1249
P+SS P ++ PL +P A M + P + P P + H+L
Sbjct: 4216 PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPP----STPTAPTTTSGGHTLSPP 4271
Query: 1250 PSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDP 1305
PS +S P T G + G +P S Q + ++ PTP P
Sbjct: 4272 PSTTTSPPGTPTRGTTTGSSSAP--------------TPSTVQTTTTSAWTPTPTP 4313
Score = 48.9 bits (115), Expect = 4e-05
Identities = 41/157 (26%), Positives = 60/157 (38%), Gaps = 13/157 (8%)
Query: 1027 PSSSSGLG--TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQ 1084
P+S++ L T+PS P T+ PT + P + P + TP P + SSPI
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT 1688
Query: 1085 PA-------TPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLA 1137
P+ TP P P+ P+ P P PP PS + PSP
Sbjct: 1689 PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP----PPTTMTTPSPTTTPSPPTTTM 1744
Query: 1138 GPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1174
P +++ T P I+ P ++ TP
Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781
Score = 42.4 bits (98), Expect = 0.003
Identities = 80/376 (21%), Positives = 123/376 (32%), Gaps = 34/376 (9%)
Query: 1027 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPA 1086
PSS T+PSS+ T+P PT P P+ P + T PP+ SSP+ P
Sbjct: 1705 PSSPITTTTTPSST--TTPSPPPTTMTTPSPTTTPSPP-TTTMTTLPPTTTSSPLTTTPL 1761
Query: 1087 TPLPQKDPAQPLEPKRPPPP-RPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYS 1145
P P P P P+ T +P + GPG A
Sbjct: 1762 PPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANI 1821
Query: 1146 TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1205
+ R T+ P + G+L Q+ + S G E KP P
Sbjct: 1822 SCRATMYPDVPI------------GQL---GQTVVCDVSVGLICKNEDQKPGGVIPMAFC 1866
Query: 1206 LPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQV-KTNGI 1264
L + V P + TPP P + ++ P+ + Q T I
Sbjct: 1867 LNYEIN--VQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1924
Query: 1265 SDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVS 1324
+ +P + ++ T+ PTP P Q P+ T ++V+
Sbjct: 1925 TTTTTVTPTPTPT------GTQTPTTTPITTTTTVTPTPTPTG-TQTPTTTPITTTTTVT 1977
Query: 1325 CMP----TMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEAT 1380
P T P + + +P P T T P + T P ++ T
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTT 2036
Query: 1381 SWFSKEEPVTISPFPS 1396
+ + VT +P P+
Sbjct: 2037 TPITTTTTVTPTPTPT 2052
Score = 42.4 bits (98), Expect = 0.003
Identities = 74/389 (19%), Positives = 126/389 (32%), Gaps = 34/389 (8%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 3868 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3924
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3981
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3982 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 4035
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 4036 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4094
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 4095 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4153
Query: 1322 SVSCMPTMPPIPARSQSQENMRS--------SPNPFITGL-------TRTNPFSDRTAAP 1366
++ T+ P P + +Q + +P P TG T T P ++ T +
Sbjct: 4154 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSN 4213
Query: 1367 GNPFRAKSEESEATSWFSKEEPVTISPFP 1395
P + + S +TS E +S P
Sbjct: 4214 PPPESSTPQTSRSTSSPLTESTTLLSTLP 4242
Score = 41.6 bits (96), Expect = 0.006
Identities = 71/391 (18%), Positives = 122/391 (31%), Gaps = 32/391 (8%)
Query: 1026 QPSSSSGLGTSPSSSPRTSPCQSPT-ISEGPVPSLPIRPSRAP-----SRTPGPPSAQSS 1079
QP++ + T + P T+P + T ++ P P+ P+ P + TP P +
Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 1940
Query: 1080 PIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AG 1135
P T P + P P+ T P P P+G P+
Sbjct: 1941 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTT 1997
Query: 1136 LAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLK 1195
P P T PT P + + G TP + T+ T T P P
Sbjct: 1998 TVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTP 2051
Query: 1196 PQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASS 1255
P + + P P P + P T P + + + ++
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110
Query: 1256 QPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSAT 1315
V G ++P + + T+P+ T P+ T
Sbjct: 2111 TTTVTPTPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2169
Query: 1316 QSNVLSSVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAA 1365
Q+ + ++ T+ P P + +Q + +P P T T P + T
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2229
Query: 1366 PGNPFRAKSEESEATSWFSKEEPVTISPFPS 1396
P ++ T+ + VT +P P+
Sbjct: 2230 TPTP-TPTGTQTPTTTPITTTTTVTPTPTPT 2259
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 1959 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2015
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2016 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2072
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2073 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2126
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2127 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2185
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2186 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2244
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2245 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2303
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPTPTPT 2328
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2028 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2084
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2085 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2141
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2142 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2195
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2196 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2254
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2255 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2313
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2314 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2372
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPT 2397
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2153
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2210
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2211 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2264
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2265 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2323
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2324 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2382
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2383 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2441
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPT 2466
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2222
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2223 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2279
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2280 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2333
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2334 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2392
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2393 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2452 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2510
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPT 2535
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2291
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2292 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2348
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2402
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2403 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2462 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2520
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2521 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2579
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPT 2604
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2360
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2361 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2417
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2418 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2471
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2472 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2531 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2589
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2590 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2648
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPT 2673
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2429
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2430 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2486
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2487 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2540
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2541 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2599
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2600 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2658
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2659 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2717
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPT 2742
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2498
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2499 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2555
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2556 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2609
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2610 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2669 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2727
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2728 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2786
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPT 2811
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2567
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2568 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2624
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2625 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2678
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2679 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2738 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2796
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2797 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2855
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPT 2880
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2636
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2637 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2693
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2694 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2747
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2748 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2806
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2807 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2865
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2866 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2924
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPT 2949
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2705
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2706 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2762
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2763 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2816
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2817 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2876 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2934
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 2935 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 2993
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPT 3018
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2774
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2775 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2831
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2832 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2885
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2886 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2944
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 2945 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3003
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3004 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3062
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPT 3087
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2843
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2844 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2900
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2901 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 2954
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 2955 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3014 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3072
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3073 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3131
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPT 3156
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2912
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2913 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 2969
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 2970 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3023
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3024 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3082
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3083 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3141
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3142 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3200
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPT 3225
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 2981
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 2982 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3038
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3039 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3092
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3093 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3152 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3210
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3211 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3269
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPT 3294
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3050
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 3051 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3107
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3108 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3161
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3162 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3220
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3221 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3338
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPT 3363
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3119
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 3120 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3176
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3177 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3230
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3231 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3289
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3290 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3348
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3349 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3407
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPT 3432
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3188
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 3189 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3245
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3246 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3299
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3300 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3358
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3359 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3418 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3476
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPT 3501
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3257
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 3258 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3314
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3315 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3368
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3369 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3428 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3486
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3487 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3545
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPT 3570
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3326
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 3327 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3383
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3384 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3437
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3438 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3497 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3555
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3556 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3614
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPT 3639
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3395
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 3396 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3452
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3453 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3506
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3507 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3566 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3624
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3625 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3683
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3684 PTGTQTPTTTPITTTTTVTPTPTPT 3708
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3464
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 3465 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3521
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3522 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3575
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3576 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3635 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3693
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3694 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3752
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPT 3777
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3533
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 3534 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3590
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3591 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3644
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3645 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3704 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3762
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3763 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3821
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPT 3846
Score = 40.4 bits (93), Expect = 0.013
Identities = 71/385 (18%), Positives = 123/385 (31%), Gaps = 30/385 (7%)
Query: 1027 PSSSSGLGTSPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+ + T+P ++ T +P +PT ++ P + PI + + TP P Q+ P
Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPT--TTP 3602
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQ----AGLAGPGP 1141
T P + P P+ T P P P+G P+ P P
Sbjct: 3603 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTP 3659
Query: 1142 AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP 1201
T PT P + + G TP + T+ T T P P P
Sbjct: 3660 TPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTT----TVTPTPTPTGTQTP 3713
Query: 1202 PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
+ + P P P + P T P + + + ++ V
Sbjct: 3714 TTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3772
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
G ++P + + T+P+ T P+ TQ+ +
Sbjct: 3773 TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3831
Query: 1322 SVSCMPTMPPIPARSQSQ----------ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
++ T+ P P + +Q + +P P T T P + T P
Sbjct: 3832 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-T 3890
Query: 1372 AKSEESEATSWFSKEEPVTISPFPS 1396
++ T+ + VT +P P+
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPT 3915
Score = 36.6 bits (83), Expect = 0.19
Identities = 35/134 (26%), Positives = 52/134 (38%), Gaps = 10/134 (7%)
Query: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPT-----ISEGPVPSLPIRPSRAPSRTPGPPSA 1076
P Q +++ + T+ + +P +P + T S P+ L S TP +
Sbjct: 4167 PTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 4226
Query: 1077 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGL 1136
SSP+ + T L PA + PP P AP T PPPS + P G
Sbjct: 4227 TSSPL-TESTTLLSTLPPAIEMT-STAPPSTPTAPTTTSGGHTLSPPPSTTTSP---PGT 4281
Query: 1137 AGPGPAGYSTARPT 1150
G S++ PT
Sbjct: 4282 PTRGTTTGSSSAPT 4295
Score = 32.0 bits (71), Expect = 4.7
Identities = 13/38 (34%), Positives = 21/38 (55%), Gaps = 4/38 (10%)
Query: 1085 PATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1122
P+TP P P++ P P +P + P++P P +PP
Sbjct: 4377 PSTPSPTPTPSK----STPTPSKPSSTPSKPTPGTKPP 4410
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 93.2 bits (230), Expect = 2e-18
Identities = 114/497 (22%), Positives = 179/497 (36%), Gaps = 30/497 (6%)
Query: 1035 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1094
T+ S+P T +PT ++ P P+ P P+ ++ P P + +S+P + P K P
Sbjct: 250 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 309
Query: 1095 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPT 1150
A P PK P P P P P PAP + P P+ +P+P A P P PT
Sbjct: 310 A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP-KKPAPTTPKEPAPT 367
Query: 1151 IP--PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPP 1208
P P P T +S T++ +T P P+ P + P
Sbjct: 368 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 427
Query: 1209 PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRS--RSSHSLPSEASSQPQVKTNGISD 1266
P + P P + +P TP +P P + + + + P E + +T +
Sbjct: 428 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 487
Query: 1267 GK--RESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVS 1324
K +P K+ P + + P PT + P A N +
Sbjct: 488 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 547
Query: 1325 CMPTMPPIPARSQSQENMRSSPNPFI-TGLTRTNPFSDRTAAPGNPFRAKSEESEATSWF 1383
PT P PA + +E ++P T T P + + AP P + +E T+
Sbjct: 548 --PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 605
Query: 1384 SKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDF 1443
P P+ K A ++ + + T PKG +E
Sbjct: 606 EPTSTTCDKPAPTTP-----KGTAPTTPKEPAPTTPKEPAPT----TPKGTAPTTLKEPA 656
Query: 1444 GVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGT 1503
K K A +L P++ G T +D T + + P P P P T
Sbjct: 657 PTTPK-KPAPKEL---APTTTKGPTSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPT 711
Query: 1504 SPPVDPFTTLASKASPT 1520
+P P TT + ++PT
Sbjct: 712 TPETPPPTT-SEVSTPT 727
Score = 77.0 bits (188), Expect = 1e-13
Identities = 84/396 (21%), Positives = 131/396 (33%), Gaps = 52/396 (13%)
Query: 1027 PSSSSGLGTSPSSSPRTSPCQ-SPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+++ T+P T+P + +PT + P P+ P P+ + P P + + +P +
Sbjct: 288 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 347
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAP------------PTRPAPPQRPPPPSGRSQPSPQ 1133
P K PA P PK P P P P P PAP P+ +P+P
Sbjct: 348 PAPTAPKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406
Query: 1134 AGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTS--ETSKGSTFLP 1191
+ P + T P P TP+ + T+ E + +T P
Sbjct: 407 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 466
Query: 1192 EPLKPQAAFP--PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNL------ETPPQPPPRS 1243
P P+ P P+ + P ++L AP P P TP +P P +
Sbjct: 467 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 526
Query: 1244 RSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTP 1303
+ + ++ P +E P P E P PT
Sbjct: 527 PEEPAPTTPKAAAPNTPKEPAPTTPKE-PAPTTPKE-------------------PAPTT 566
Query: 1304 DPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSP------NPFITGLTRTN 1357
+ P T L + PT P PA + P P T T
Sbjct: 567 PKETAPTTPKGTAPTTLKEPA--PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 624
Query: 1358 PFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISP 1393
P + + AP P + T+ + +EP +P
Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 660
Score = 70.1 bits (170), Expect = 2e-11
Identities = 120/558 (21%), Positives = 194/558 (34%), Gaps = 77/558 (13%)
Query: 973 EEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSG 1032
+E S+EK S + TS L + A+ +G E P+ +P+S++
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPK--EPASTTP 229
Query: 1033 LGTSPS---SSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPL 1089
+P+ S+P T +PT ++ P+ P P+ ++ P P + + +PA P
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKS-APTTPKEPAPTTTKEPAPTTPK------EPA-PT 281
Query: 1090 PQKDPAQPLEPKRPPPPRPVAP--PTRPAP-PQRPPPPSGRSQPSPQAGLAGPGPAGYST 1146
K+PA P P+ AP P +PAP + P P+ +P+P P P
Sbjct: 282 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPAPTTKEP 340
Query: 1147 ARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL 1206
A T P+ +AP+ A + P + + + T +T P P P+ P +
Sbjct: 341 APTT--PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT---TTKEPSPTTPKEPAPTTTKS 395
Query: 1207 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE-ASSQPQVKTNGIS 1265
P + P +AP P P P P + + P + A + P
Sbjct: 396 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-------- 447
Query: 1266 DGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSC 1325
+ P P E K + P PT + P ++
Sbjct: 448 ----KEPAPTTPKEPAP---TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA- 499
Query: 1326 MPTMPPIPARSQSQENMRSSP-NPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFS 1384
PT P PA + +E ++P P T P + + AAP P + + +
Sbjct: 500 -PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 558
Query: 1385 KEEPVTISPFPSLQPLGHNKSRASSSLDG-FKDSFDLQGQSTLKISNPKGWVTFEEEEDF 1443
+EP +P K A ++ G + +T K PK E
Sbjct: 559 PKEPAPTTP----------KETAPTTPKGTAPTTLKEPAPTTPKKPAPK------ELAPT 602
Query: 1444 GVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGT 1503
K + + C P KGT + P+ P P P P GT
Sbjct: 603 TTKEPTSTTCDKPAPTTP---------------KGTAPTTPKEPAPTTPKEPAPTTPKGT 647
Query: 1504 SPPV--DPFTTLASKASP 1519
+P +P T K +P
Sbjct: 648 APTTLKEPAPTTPKKPAP 665
Score = 62.0 bits (149), Expect = 4e-09
Identities = 65/262 (24%), Positives = 103/262 (39%), Gaps = 29/262 (11%)
Query: 1035 TSPSSSPRTSPCQSPTISEGPVPSLPIRPS---RAPSRTPGPPS------AQSSPIDAQP 1085
T ++P T +PT + P P+ P +P+ AP+ T P S A ++P P
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625
Query: 1086 ATPLPQKDPAQPLEPKRPPP--PRPVAPPTRPAP-PQRPPPPSGRSQPSPQAGLAGPGPA 1142
TP K+PA P PK P P P+ AP T P P P P+ P A GP
Sbjct: 626 TTP---KEPA-PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA----PKELAPTTTKGPT 677
Query: 1143 GYSTARPT-IPPRAGVISAPQSHARASAGR---LTPESQSKTSETSKGSTFLPEPL---- 1194
++ +P P+ + P+ A + + TPE+ T+ T EP
Sbjct: 678 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 737
Query: 1195 KPQAAFPPQSSLPPPAQRLQEPLVP-VAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEA 1253
P + P S+ P P P P V + +P + T + R + P
Sbjct: 738 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 797
Query: 1254 SSQPQVKTNGISDGKRESPLKI 1275
++ P++ + ++ + KI
Sbjct: 798 TAAPKMTKETATTTEKTTESKI 819
Score = 54.7 bits (130), Expect = 7e-07
Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 34/193 (17%)
Query: 1026 QPSSSSGLGTSPSS------------SPRTSPCQSPTISEGPVPSLPIRPS---RAPSRT 1070
+P+ ++ GT+P++ +P T +PT + P P+ P +P+ AP+ T
Sbjct: 614 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 673
Query: 1071 PGPPSAQS---SPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPP------TRPAPPQRP 1121
GP S S +P + P K+PA P PK+P P P PP + P + P
Sbjct: 674 KGPTSTTSDKPAPTTPKETAPTTPKEPA-PTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 732
Query: 1122 ---------PPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRL 1172
P ++P+P+A P G T + + + + + R
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 792
Query: 1173 TPESQSKTSETSK 1185
TPE+ + + +K
Sbjct: 793 TPETTTAAPKMTK 805
Score = 49.3 bits (116), Expect = 3e-05
Identities = 58/292 (19%), Positives = 108/292 (36%), Gaps = 11/292 (3%)
Query: 1022 PQHLQPSSSSG--LGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ-S 1078
P+ L P+++ G TS +P T +PT + P P+ P +P+ TP P +++ S
Sbjct: 665 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 724
Query: 1079 SPIDA-QPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLA 1137
+P +P T D + P P P P P P P + + + + A
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 784
Query: 1138 GPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGST-FLPEPLKP 1196
+T T + + + ++T + TS T++ +T F LK
Sbjct: 785 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 844
Query: 1197 QAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQP--PPRSRSSHSLPSEAS 1254
P ++ + P P+ + T P+P P ++ + +
Sbjct: 845 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 904
Query: 1255 SQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPK 1306
+ P+V+ + R+ + S +++A L T P TP+ K
Sbjct: 905 TMPRVRKPKTTPTPRKMTSTMPELNPTS----RIAEAMLQTTTRPNQTPNSK 952
Score = 31.2 bits (69), Expect = 8.0
Identities = 43/210 (20%), Positives = 78/210 (37%), Gaps = 22/210 (10%)
Query: 964 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1013
KSPD E+S E AL +S T + E A D E D+
Sbjct: 737 KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 792
Query: 1014 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1070
+ E P+ + ++++ T+ S T+ + T ++ P + + AP T
Sbjct: 793 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852
Query: 1071 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQP 1130
+ ++ I +P KD A + P P +P P +P ++P ++ P
Sbjct: 853 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP-----KTMP 907
Query: 1131 SPQAGLAGPGPAGYSTARPTIPPRAGVISA 1160
+ P P ++ P + P + + A
Sbjct: 908 RVRKPKTTPTPRKMTSTMPELNPTSRIAEA 937
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 93.2 bits (230), Expect = 2e-18
Identities = 114/497 (22%), Positives = 179/497 (36%), Gaps = 30/497 (6%)
Query: 1035 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1094
T+ S+P T +PT ++ P P+ P P+ ++ P P + +S+P + P K P
Sbjct: 291 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 350
Query: 1095 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPT 1150
A P PK P P P P P PAP + P P+ +P+P A P P PT
Sbjct: 351 A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP-KKPAPTTPKEPAPT 408
Query: 1151 IP--PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPP 1208
P P P T +S T++ +T P P+ P + P
Sbjct: 409 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 468
Query: 1209 PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRS--RSSHSLPSEASSQPQVKTNGISD 1266
P + P P + +P TP +P P + + + + P E + +T +
Sbjct: 469 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 528
Query: 1267 GK--RESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVS 1324
K +P K+ P + + P PT + P A N +
Sbjct: 529 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 588
Query: 1325 CMPTMPPIPARSQSQENMRSSPNPFI-TGLTRTNPFSDRTAAPGNPFRAKSEESEATSWF 1383
PT P PA + +E ++P T T P + + AP P + +E T+
Sbjct: 589 --PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 646
Query: 1384 SKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDF 1443
P P+ K A ++ + + T PKG +E
Sbjct: 647 EPTSTTCDKPAPTTP-----KGTAPTTPKEPAPTTPKEPAPT----TPKGTAPTTLKEPA 697
Query: 1444 GVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGT 1503
K K A +L P++ G T +D T + + P P P P T
Sbjct: 698 PTTPK-KPAPKEL---APTTTKGPTSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPT 752
Query: 1504 SPPVDPFTTLASKASPT 1520
+P P TT + ++PT
Sbjct: 753 TPETPPPTT-SEVSTPT 768
Score = 77.0 bits (188), Expect = 1e-13
Identities = 84/396 (21%), Positives = 131/396 (33%), Gaps = 52/396 (13%)
Query: 1027 PSSSSGLGTSPSSSPRTSPCQ-SPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+++ T+P T+P + +PT + P P+ P P+ + P P + + +P +
Sbjct: 329 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 388
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAP------------PTRPAPPQRPPPPSGRSQPSPQ 1133
P K PA P PK P P P P P PAP P+ +P+P
Sbjct: 389 PAPTAPKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447
Query: 1134 AGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTS--ETSKGSTFLP 1191
+ P + T P P TP+ + T+ E + +T P
Sbjct: 448 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 507
Query: 1192 EPLKPQAAFP--PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNL------ETPPQPPPRS 1243
P P+ P P+ + P ++L AP P P TP +P P +
Sbjct: 508 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 567
Query: 1244 RSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTP 1303
+ + ++ P +E P P E P PT
Sbjct: 568 PEEPAPTTPKAAAPNTPKEPAPTTPKE-PAPTTPKE-------------------PAPTT 607
Query: 1304 DPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSP------NPFITGLTRTN 1357
+ P T L + PT P PA + P P T T
Sbjct: 608 PKETAPTTPKGTAPTTLKEPA--PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 665
Query: 1358 PFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISP 1393
P + + AP P + T+ + +EP +P
Sbjct: 666 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 701
Score = 70.1 bits (170), Expect = 2e-11
Identities = 120/558 (21%), Positives = 194/558 (34%), Gaps = 77/558 (13%)
Query: 973 EEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSG 1032
+E S+EK S + TS L + A+ +G E P+ +P+S++
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPK--EPASTTP 270
Query: 1033 LGTSPS---SSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPL 1089
+P+ S+P T +PT ++ P+ P P+ ++ P P + + +PA P
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKS-APTTPKEPAPTTTKEPAPTTPK------EPA-PT 322
Query: 1090 PQKDPAQPLEPKRPPPPRPVAP--PTRPAP-PQRPPPPSGRSQPSPQAGLAGPGPAGYST 1146
K+PA P P+ AP P +PAP + P P+ +P+P P P
Sbjct: 323 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPAPTTKEP 381
Query: 1147 ARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL 1206
A T P+ +AP+ A + P + + + T +T P P P+ P +
Sbjct: 382 APTT--PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT---TTKEPSPTTPKEPAPTTTKS 436
Query: 1207 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE-ASSQPQVKTNGIS 1265
P + P +AP P P P P + + P + A + P
Sbjct: 437 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-------- 488
Query: 1266 DGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSC 1325
+ P P E K + P PT + P ++
Sbjct: 489 ----KEPAPTTPKEPAP---TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA- 540
Query: 1326 MPTMPPIPARSQSQENMRSSP-NPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFS 1384
PT P PA + +E ++P P T P + + AAP P + + +
Sbjct: 541 -PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 599
Query: 1385 KEEPVTISPFPSLQPLGHNKSRASSSLDG-FKDSFDLQGQSTLKISNPKGWVTFEEEEDF 1443
+EP +P K A ++ G + +T K PK E
Sbjct: 600 PKEPAPTTP----------KETAPTTPKGTAPTTLKEPAPTTPKKPAPK------ELAPT 643
Query: 1444 GVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGT 1503
K + + C P KGT + P+ P P P P GT
Sbjct: 644 TTKEPTSTTCDKPAPTTP---------------KGTAPTTPKEPAPTTPKEPAPTTPKGT 688
Query: 1504 SPPV--DPFTTLASKASP 1519
+P +P T K +P
Sbjct: 689 APTTLKEPAPTTPKKPAP 706
Score = 62.0 bits (149), Expect = 4e-09
Identities = 65/262 (24%), Positives = 103/262 (39%), Gaps = 29/262 (11%)
Query: 1035 TSPSSSPRTSPCQSPTISEGPVPSLPIRPS---RAPSRTPGPPS------AQSSPIDAQP 1085
T ++P T +PT + P P+ P +P+ AP+ T P S A ++P P
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666
Query: 1086 ATPLPQKDPAQPLEPKRPPP--PRPVAPPTRPAP-PQRPPPPSGRSQPSPQAGLAGPGPA 1142
TP K+PA P PK P P P+ AP T P P P P+ P A GP
Sbjct: 667 TTP---KEPA-PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA----PKELAPTTTKGPT 718
Query: 1143 GYSTARPT-IPPRAGVISAPQSHARASAGR---LTPESQSKTSETSKGSTFLPEPL---- 1194
++ +P P+ + P+ A + + TPE+ T+ T EP
Sbjct: 719 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 778
Query: 1195 KPQAAFPPQSSLPPPAQRLQEPLVP-VAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEA 1253
P + P S+ P P P P V + +P + T + R + P
Sbjct: 779 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 838
Query: 1254 SSQPQVKTNGISDGKRESPLKI 1275
++ P++ + ++ + KI
Sbjct: 839 TAAPKMTKETATTTEKTTESKI 860
Score = 54.7 bits (130), Expect = 7e-07
Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 34/193 (17%)
Query: 1026 QPSSSSGLGTSPSS------------SPRTSPCQSPTISEGPVPSLPIRPS---RAPSRT 1070
+P+ ++ GT+P++ +P T +PT + P P+ P +P+ AP+ T
Sbjct: 655 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 714
Query: 1071 PGPPSAQS---SPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPP------TRPAPPQRP 1121
GP S S +P + P K+PA P PK+P P P PP + P + P
Sbjct: 715 KGPTSTTSDKPAPTTPKETAPTTPKEPA-PTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 773
Query: 1122 ---------PPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRL 1172
P ++P+P+A P G T + + + + + R
Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 833
Query: 1173 TPESQSKTSETSK 1185
TPE+ + + +K
Sbjct: 834 TPETTTAAPKMTK 846
Score = 49.3 bits (116), Expect = 3e-05
Identities = 58/292 (19%), Positives = 108/292 (36%), Gaps = 11/292 (3%)
Query: 1022 PQHLQPSSSSG--LGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ-S 1078
P+ L P+++ G TS +P T +PT + P P+ P +P+ TP P +++ S
Sbjct: 706 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 765
Query: 1079 SPIDA-QPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLA 1137
+P +P T D + P P P P P P P + + + + A
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 825
Query: 1138 GPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGST-FLPEPLKP 1196
+T T + + + ++T + TS T++ +T F LK
Sbjct: 826 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 885
Query: 1197 QAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQP--PPRSRSSHSLPSEAS 1254
P ++ + P P+ + T P+P P ++ + +
Sbjct: 886 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 945
Query: 1255 SQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPK 1306
+ P+V+ + R+ + S +++A L T P TP+ K
Sbjct: 946 TMPRVRKPKTTPTPRKMTSTMPELNPTS----RIAEAMLQTTTRPNQTPNSK 993
Score = 31.2 bits (69), Expect = 8.0
Identities = 43/210 (20%), Positives = 78/210 (37%), Gaps = 22/210 (10%)
Query: 964 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1013
KSPD E+S E AL +S T + E A D E D+
Sbjct: 778 KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 833
Query: 1014 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1070
+ E P+ + ++++ T+ S T+ + T ++ P + + AP T
Sbjct: 834 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893
Query: 1071 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQP 1130
+ ++ I +P KD A + P P +P P +P ++P ++ P
Sbjct: 894 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP-----KTMP 948
Query: 1131 SPQAGLAGPGPAGYSTARPTIPPRAGVISA 1160
+ P P ++ P + P + + A
Sbjct: 949 RVRKPKTTPTPRKMTSTMPELNPTSRIAEA 978
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 93.2 bits (230), Expect = 2e-18
Identities = 114/497 (22%), Positives = 179/497 (36%), Gaps = 30/497 (6%)
Query: 1035 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1094
T+ S+P T +PT ++ P P+ P P+ ++ P P + +S+P + P K P
Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402
Query: 1095 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPT 1150
A P PK P P P P P PAP + P P+ +P+P A P P PT
Sbjct: 403 A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP-KKPAPTTPKEPAPT 460
Query: 1151 IP--PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPP 1208
P P P T +S T++ +T P P+ P + P
Sbjct: 461 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 520
Query: 1209 PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRS--RSSHSLPSEASSQPQVKTNGISD 1266
P + P P + +P TP +P P + + + + P E + +T +
Sbjct: 521 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580
Query: 1267 GK--RESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVS 1324
K +P K+ P + + P PT + P A N +
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 640
Query: 1325 CMPTMPPIPARSQSQENMRSSPNPFI-TGLTRTNPFSDRTAAPGNPFRAKSEESEATSWF 1383
PT P PA + +E ++P T T P + + AP P + +E T+
Sbjct: 641 --PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 698
Query: 1384 SKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDF 1443
P P+ K A ++ + + T PKG +E
Sbjct: 699 EPTSTTCDKPAPTTP-----KGTAPTTPKEPAPTTPKEPAPT----TPKGTAPTTLKEPA 749
Query: 1444 GVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGT 1503
K K A +L P++ G T +D T + + P P P P T
Sbjct: 750 PTTPK-KPAPKEL---APTTTKGPTSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPT 804
Query: 1504 SPPVDPFTTLASKASPT 1520
+P P TT + ++PT
Sbjct: 805 TPETPPPTT-SEVSTPT 820
Score = 77.0 bits (188), Expect = 1e-13
Identities = 84/396 (21%), Positives = 131/396 (33%), Gaps = 52/396 (13%)
Query: 1027 PSSSSGLGTSPSSSPRTSPCQ-SPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+++ T+P T+P + +PT + P P+ P P+ + P P + + +P +
Sbjct: 381 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 440
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAP------------PTRPAPPQRPPPPSGRSQPSPQ 1133
P K PA P PK P P P P P PAP P+ +P+P
Sbjct: 441 PAPTAPKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 499
Query: 1134 AGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTS--ETSKGSTFLP 1191
+ P + T P P TP+ + T+ E + +T P
Sbjct: 500 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 559
Query: 1192 EPLKPQAAFP--PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNL------ETPPQPPPRS 1243
P P+ P P+ + P ++L AP P P TP +P P +
Sbjct: 560 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 619
Query: 1244 RSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTP 1303
+ + ++ P +E P P E P PT
Sbjct: 620 PEEPAPTTPKAAAPNTPKEPAPTTPKE-PAPTTPKE-------------------PAPTT 659
Query: 1304 DPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSP------NPFITGLTRTN 1357
+ P T L + PT P PA + P P T T
Sbjct: 660 PKETAPTTPKGTAPTTLKEPA--PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 717
Query: 1358 PFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISP 1393
P + + AP P + T+ + +EP +P
Sbjct: 718 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 753
Score = 70.1 bits (170), Expect = 2e-11
Identities = 120/558 (21%), Positives = 194/558 (34%), Gaps = 77/558 (13%)
Query: 973 EEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSG 1032
+E S+EK S + TS L + A+ +G E P+ +P+S++
Sbjct: 267 KETQSIEKTSAKDLAPTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPK--EPASTTP 322
Query: 1033 LGTSPS---SSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPL 1089
+P+ S+P T +PT ++ P+ P P+ ++ P P + + +PA P
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKS-APTTPKEPAPTTTKEPAPTTPK------EPA-PT 374
Query: 1090 PQKDPAQPLEPKRPPPPRPVAP--PTRPAP-PQRPPPPSGRSQPSPQAGLAGPGPAGYST 1146
K+PA P P+ AP P +PAP + P P+ +P+P P P
Sbjct: 375 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPAPTTKEP 433
Query: 1147 ARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL 1206
A T P+ +AP+ A + P + + + T +T P P P+ P +
Sbjct: 434 APTT--PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT---TTKEPSPTTPKEPAPTTTKS 488
Query: 1207 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE-ASSQPQVKTNGIS 1265
P + P +AP P P P P + + P + A + P
Sbjct: 489 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-------- 540
Query: 1266 DGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSC 1325
+ P P E K + P PT + P ++
Sbjct: 541 ----KEPAPTTPKEPAP---TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA- 592
Query: 1326 MPTMPPIPARSQSQENMRSSP-NPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFS 1384
PT P PA + +E ++P P T P + + AAP P + + +
Sbjct: 593 -PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 651
Query: 1385 KEEPVTISPFPSLQPLGHNKSRASSSLDG-FKDSFDLQGQSTLKISNPKGWVTFEEEEDF 1443
+EP +P K A ++ G + +T K PK E
Sbjct: 652 PKEPAPTTP----------KETAPTTPKGTAPTTLKEPAPTTPKKPAPK------ELAPT 695
Query: 1444 GVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGT 1503
K + + C P KGT + P+ P P P P GT
Sbjct: 696 TTKEPTSTTCDKPAPTTP---------------KGTAPTTPKEPAPTTPKEPAPTTPKGT 740
Query: 1504 SPPV--DPFTTLASKASP 1519
+P +P T K +P
Sbjct: 741 APTTLKEPAPTTPKKPAP 758
Score = 62.0 bits (149), Expect = 4e-09
Identities = 65/262 (24%), Positives = 103/262 (39%), Gaps = 29/262 (11%)
Query: 1035 TSPSSSPRTSPCQSPTISEGPVPSLPIRPS---RAPSRTPGPPS------AQSSPIDAQP 1085
T ++P T +PT + P P+ P +P+ AP+ T P S A ++P P
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718
Query: 1086 ATPLPQKDPAQPLEPKRPPP--PRPVAPPTRPAP-PQRPPPPSGRSQPSPQAGLAGPGPA 1142
TP K+PA P PK P P P+ AP T P P P P+ P A GP
Sbjct: 719 TTP---KEPA-PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA----PKELAPTTTKGPT 770
Query: 1143 GYSTARPT-IPPRAGVISAPQSHARASAGR---LTPESQSKTSETSKGSTFLPEPL---- 1194
++ +P P+ + P+ A + + TPE+ T+ T EP
Sbjct: 771 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 830
Query: 1195 KPQAAFPPQSSLPPPAQRLQEPLVP-VAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEA 1253
P + P S+ P P P P V + +P + T + R + P
Sbjct: 831 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 890
Query: 1254 SSQPQVKTNGISDGKRESPLKI 1275
++ P++ + ++ + KI
Sbjct: 891 TAAPKMTKETATTTEKTTESKI 912
Score = 54.7 bits (130), Expect = 7e-07
Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 34/193 (17%)
Query: 1026 QPSSSSGLGTSPSS------------SPRTSPCQSPTISEGPVPSLPIRPS---RAPSRT 1070
+P+ ++ GT+P++ +P T +PT + P P+ P +P+ AP+ T
Sbjct: 707 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 766
Query: 1071 PGPPSAQS---SPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPP------TRPAPPQRP 1121
GP S S +P + P K+PA P PK+P P P PP + P + P
Sbjct: 767 KGPTSTTSDKPAPTTPKETAPTTPKEPA-PTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 825
Query: 1122 ---------PPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRL 1172
P ++P+P+A P G T + + + + + R
Sbjct: 826 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 885
Query: 1173 TPESQSKTSETSK 1185
TPE+ + + +K
Sbjct: 886 TPETTTAAPKMTK 898
Score = 49.3 bits (116), Expect = 3e-05
Identities = 58/292 (19%), Positives = 108/292 (36%), Gaps = 11/292 (3%)
Query: 1022 PQHLQPSSSSG--LGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ-S 1078
P+ L P+++ G TS +P T +PT + P P+ P +P+ TP P +++ S
Sbjct: 758 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 817
Query: 1079 SPIDA-QPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLA 1137
+P +P T D + P P P P P P P + + + + A
Sbjct: 818 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 877
Query: 1138 GPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGST-FLPEPLKP 1196
+T T + + + ++T + TS T++ +T F LK
Sbjct: 878 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 937
Query: 1197 QAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQP--PPRSRSSHSLPSEAS 1254
P ++ + P P+ + T P+P P ++ + +
Sbjct: 938 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 997
Query: 1255 SQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPK 1306
+ P+V+ + R+ + S +++A L T P TP+ K
Sbjct: 998 TMPRVRKPKTTPTPRKMTSTMPELNPTS----RIAEAMLQTTTRPNQTPNSK 1045
Score = 32.3 bits (72), Expect = 3.6
Identities = 64/360 (17%), Positives = 120/360 (33%), Gaps = 63/360 (17%)
Query: 1093 DPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGR------------SQPSPQAGLAGPG 1140
+P P K+ PPP + + + P PP+ + + S
Sbjct: 68 NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 127
Query: 1141 PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQA-- 1198
+ S++ TI + S+ S A + +K + T K T P P+ +A
Sbjct: 128 SSSSSSSSSTI---RKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP-PVVDEAGS 183
Query: 1199 --------AFPPQSSLPPPAQRLQEPLVPVAAPM-PQSGPQPNLETPPQPPPRSRSSHSL 1249
P +S + P + A P+ P+ PN +T + ++
Sbjct: 184 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV 243
Query: 1250 PSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQT------------ 1297
++ ++ +T+ K S + E S LA + L+ T
Sbjct: 244 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 303
Query: 1298 ----SPVPT------------PDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQEN 1341
P PT P P + P+ + ++ PT P PA + ++E
Sbjct: 304 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 363
Query: 1342 MRSSPN---PFIT-----GLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISP 1393
++P P T T++ P + + AP P + + + + +EP +P
Sbjct: 364 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP 423
Score = 31.2 bits (69), Expect = 8.0
Identities = 43/210 (20%), Positives = 78/210 (37%), Gaps = 22/210 (10%)
Query: 964 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1013
KSPD E+S E AL +S T + E A D E D+
Sbjct: 830 KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 885
Query: 1014 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1070
+ E P+ + ++++ T+ S T+ + T ++ P + + AP T
Sbjct: 886 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 945
Query: 1071 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQP 1130
+ ++ I +P KD A + P P +P P +P ++P ++ P
Sbjct: 946 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP-----KTMP 1000
Query: 1131 SPQAGLAGPGPAGYSTARPTIPPRAGVISA 1160
+ P P ++ P + P + + A
Sbjct: 1001 RVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1030
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 93.2 bits (230), Expect = 2e-18
Identities = 114/497 (22%), Positives = 179/497 (36%), Gaps = 30/497 (6%)
Query: 1035 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1094
T+ S+P T +PT ++ P P+ P P+ ++ P P + +S+P + P K P
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443
Query: 1095 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPT 1150
A P PK P P P P P PAP + P P+ +P+P A P P PT
Sbjct: 444 A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP-KKPAPTTPKEPAPT 501
Query: 1151 IP--PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPP 1208
P P P T +S T++ +T P P+ P + P
Sbjct: 502 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 561
Query: 1209 PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRS--RSSHSLPSEASSQPQVKTNGISD 1266
P + P P + +P TP +P P + + + + P E + +T +
Sbjct: 562 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621
Query: 1267 GK--RESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVS 1324
K +P K+ P + + P PT + P A N +
Sbjct: 622 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 681
Query: 1325 CMPTMPPIPARSQSQENMRSSPNPFI-TGLTRTNPFSDRTAAPGNPFRAKSEESEATSWF 1383
PT P PA + +E ++P T T P + + AP P + +E T+
Sbjct: 682 --PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 739
Query: 1384 SKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDF 1443
P P+ K A ++ + + T PKG +E
Sbjct: 740 EPTSTTCDKPAPTTP-----KGTAPTTPKEPAPTTPKEPAPT----TPKGTAPTTLKEPA 790
Query: 1444 GVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGT 1503
K K A +L P++ G T +D T + + P P P P T
Sbjct: 791 PTTPK-KPAPKEL---APTTTKGPTSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPT 845
Query: 1504 SPPVDPFTTLASKASPT 1520
+P P TT + ++PT
Sbjct: 846 TPETPPPTT-SEVSTPT 861
Score = 77.0 bits (188), Expect = 1e-13
Identities = 84/396 (21%), Positives = 131/396 (33%), Gaps = 52/396 (13%)
Query: 1027 PSSSSGLGTSPSSSPRTSPCQ-SPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1085
P+++ T+P T+P + +PT + P P+ P P+ + P P + + +P +
Sbjct: 422 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 481
Query: 1086 ATPLPQKDPAQPLEPKRPPPPRPVAP------------PTRPAPPQRPPPPSGRSQPSPQ 1133
P K PA P PK P P P P P PAP P+ +P+P
Sbjct: 482 PAPTAPKKPA-PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 540
Query: 1134 AGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTS--ETSKGSTFLP 1191
+ P + T P P TP+ + T+ E + +T P
Sbjct: 541 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 600
Query: 1192 EPLKPQAAFP--PQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNL------ETPPQPPPRS 1243
P P+ P P+ + P ++L AP P P TP +P P +
Sbjct: 601 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 660
Query: 1244 RSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTP 1303
+ + ++ P +E P P E P PT
Sbjct: 661 PEEPAPTTPKAAAPNTPKEPAPTTPKE-PAPTTPKE-------------------PAPTT 700
Query: 1304 DPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSP------NPFITGLTRTN 1357
+ P T L + PT P PA + P P T T
Sbjct: 701 PKETAPTTPKGTAPTTLKEPA--PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 758
Query: 1358 PFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISP 1393
P + + AP P + T+ + +EP +P
Sbjct: 759 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 794
Score = 70.1 bits (170), Expect = 2e-11
Identities = 120/558 (21%), Positives = 194/558 (34%), Gaps = 77/558 (13%)
Query: 973 EEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSG 1032
+E S+EK S + TS L + A+ +G E P+ +P+S++
Sbjct: 308 KETQSIEKTSAKDLAPTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPK--EPASTTP 363
Query: 1033 LGTSPS---SSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPL 1089
+P+ S+P T +PT ++ P+ P P+ ++ P P + + +PA P
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKS-APTTPKEPAPTTTKEPAPTTPK------EPA-PT 415
Query: 1090 PQKDPAQPLEPKRPPPPRPVAP--PTRPAP-PQRPPPPSGRSQPSPQAGLAGPGPAGYST 1146
K+PA P P+ AP P +PAP + P P+ +P+P P P
Sbjct: 416 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP-KEPAPTTKEP 474
Query: 1147 ARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL 1206
A T P+ +AP+ A + P + + + T +T P P P+ P +
Sbjct: 475 APTT--PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT---TTKEPSPTTPKEPAPTTTKS 529
Query: 1207 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE-ASSQPQVKTNGIS 1265
P + P +AP P P P P + + P + A + P
Sbjct: 530 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-------- 581
Query: 1266 DGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSC 1325
+ P P E K + P PT + P ++
Sbjct: 582 ----KEPAPTTPKEPAP---TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA- 633
Query: 1326 MPTMPPIPARSQSQENMRSSP-NPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFS 1384
PT P PA + +E ++P P T P + + AAP P + + +
Sbjct: 634 -PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 692
Query: 1385 KEEPVTISPFPSLQPLGHNKSRASSSLDG-FKDSFDLQGQSTLKISNPKGWVTFEEEEDF 1443
+EP +P K A ++ G + +T K PK E
Sbjct: 693 PKEPAPTTP----------KETAPTTPKGTAPTTLKEPAPTTPKKPAPK------ELAPT 736
Query: 1444 GVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGT 1503
K + + C P KGT + P+ P P P P GT
Sbjct: 737 TTKEPTSTTCDKPAPTTP---------------KGTAPTTPKEPAPTTPKEPAPTTPKGT 781
Query: 1504 SPPV--DPFTTLASKASP 1519
+P +P T K +P
Sbjct: 782 APTTLKEPAPTTPKKPAP 799
Score = 62.0 bits (149), Expect = 4e-09
Identities = 65/262 (24%), Positives = 103/262 (39%), Gaps = 29/262 (11%)
Query: 1035 TSPSSSPRTSPCQSPTISEGPVPSLPIRPS---RAPSRTPGPPS------AQSSPIDAQP 1085
T ++P T +PT + P P+ P +P+ AP+ T P S A ++P P
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759
Query: 1086 ATPLPQKDPAQPLEPKRPPP--PRPVAPPTRPAP-PQRPPPPSGRSQPSPQAGLAGPGPA 1142
TP K+PA P PK P P P+ AP T P P P P+ P A GP
Sbjct: 760 TTP---KEPA-PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA----PKELAPTTTKGPT 811
Query: 1143 GYSTARPT-IPPRAGVISAPQSHARASAGR---LTPESQSKTSETSKGSTFLPEPL---- 1194
++ +P P+ + P+ A + + TPE+ T+ T EP
Sbjct: 812 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK 871
Query: 1195 KPQAAFPPQSSLPPPAQRLQEPLVP-VAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEA 1253
P + P S+ P P P P V + +P + T + R + P
Sbjct: 872 SPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETT 931
Query: 1254 SSQPQVKTNGISDGKRESPLKI 1275
++ P++ + ++ + KI
Sbjct: 932 TAAPKMTKETATTTEKTTESKI 953
Score = 54.7 bits (130), Expect = 7e-07
Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 34/193 (17%)
Query: 1026 QPSSSSGLGTSPSS------------SPRTSPCQSPTISEGPVPSLPIRPS---RAPSRT 1070
+P+ ++ GT+P++ +P T +PT + P P+ P +P+ AP+ T
Sbjct: 748 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 807
Query: 1071 PGPPSAQS---SPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPP------TRPAPPQRP 1121
GP S S +P + P K+PA P PK+P P P PP + P + P
Sbjct: 808 KGPTSTTSDKPAPTTPKETAPTTPKEPA-PTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 866
Query: 1122 ---------PPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRL 1172
P ++P+P+A P G T + + + + + R
Sbjct: 867 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 926
Query: 1173 TPESQSKTSETSK 1185
TPE+ + + +K
Sbjct: 927 TPETTTAAPKMTK 939
Score = 49.3 bits (116), Expect = 3e-05
Identities = 58/292 (19%), Positives = 108/292 (36%), Gaps = 11/292 (3%)
Query: 1022 PQHLQPSSSSG--LGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ-S 1078
P+ L P+++ G TS +P T +PT + P P+ P +P+ TP P +++ S
Sbjct: 799 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 858
Query: 1079 SPIDA-QPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLA 1137
+P +P T D + P P P P P P P + + + + A
Sbjct: 859 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 918
Query: 1138 GPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGST-FLPEPLKP 1196
+T T + + + ++T + TS T++ +T F LK
Sbjct: 919 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 978
Query: 1197 QAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQP--PPRSRSSHSLPSEAS 1254
P ++ + P P+ + T P+P P ++ + +
Sbjct: 979 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 1038
Query: 1255 SQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPK 1306
+ P+V+ + R+ + S +++A L T P TP+ K
Sbjct: 1039 TMPRVRKPKTTPTPRKMTSTMPELNPTS----RIAEAMLQTTTRPNQTPNSK 1086
Score = 32.3 bits (72), Expect = 3.6
Identities = 64/360 (17%), Positives = 120/360 (33%), Gaps = 63/360 (17%)
Query: 1093 DPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGR------------SQPSPQAGLAGPG 1140
+P P K+ PPP + + + P PP+ + + S
Sbjct: 109 NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 168
Query: 1141 PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQA-- 1198
+ S++ TI + S+ S A + +K + T K T P P+ +A
Sbjct: 169 SSSSSSSSSTI---RKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP-PVVDEAGS 224
Query: 1199 --------AFPPQSSLPPPAQRLQEPLVPVAAPM-PQSGPQPNLETPPQPPPRSRSSHSL 1249
P +S + P + A P+ P+ PN +T + ++
Sbjct: 225 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV 284
Query: 1250 PSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQT------------ 1297
++ ++ +T+ K S + E S LA + L+ T
Sbjct: 285 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 344
Query: 1298 ----SPVPT------------PDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQEN 1341
P PT P P + P+ + ++ PT P PA + ++E
Sbjct: 345 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 404
Query: 1342 MRSSPN---PFIT-----GLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISP 1393
++P P T T++ P + + AP P + + + + +EP +P
Sbjct: 405 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP 464
Score = 31.2 bits (69), Expect = 8.0
Identities = 43/210 (20%), Positives = 78/210 (37%), Gaps = 22/210 (10%)
Query: 964 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1013
KSPD E+S E AL +S T + E A D E D+
Sbjct: 871 KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 926
Query: 1014 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1070
+ E P+ + ++++ T+ S T+ + T ++ P + + AP T
Sbjct: 927 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 986
Query: 1071 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQP 1130
+ ++ I +P KD A + P P +P P +P ++P ++ P
Sbjct: 987 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP-----KTMP 1041
Query: 1131 SPQAGLAGPGPAGYSTARPTIPPRAGVISA 1160
+ P P ++ P + P + + A
Sbjct: 1042 RVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1071
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 91.7 bits (226), Expect = 5e-18
Identities = 137/563 (24%), Positives = 191/563 (33%), Gaps = 79/563 (14%)
Query: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG-----PVPSLPIRPSRAPS------RT 1070
P PS GL T P T+P +P +G P P P+ P T
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165
Query: 1071 PGPPSAQSSPIDAQP------ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP 1124
P P A ++P P ATP P+ P P PP P P+P P P
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP----AATPPSPKGGLATPSPKGAPTTP 1221
Query: 1125 SGRSQPSPQAGLAGPGPAGYSTARPTIP--PRAGVISAPQSHARASAGRLTPESQ-SKTS 1181
+ + PSP+ GLA P P G T P P+ G + P A P + +
Sbjct: 1222 AA-TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280
Query: 1182 ETSKGS-----TFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETP 1236
KG+ P P A PP+ + PPA P P P+ P P TP
Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340
Query: 1237 PQP------PPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSK 1290
P P P + SS P+ SS+ + + P P S
Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP----SPKRGPAIP 1396
Query: 1291 AQLSVQTSPVPTP-DPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPF 1349
+ TSP P PK+ P + S + T P + S + S+P
Sbjct: 1397 SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL-TPPAVTPVSLKKAPATSAPK-- 1453
Query: 1350 ITGLTRTNPFSDRT---AAPGNPFRAKSEESEATSWFSKEEPVTISP-----FPSLQPLG 1401
G + D T P +P + + ATS K+ P T +P P++ P
Sbjct: 1454 -GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512
Query: 1402 HNKSRA--SSSLDGFKDSFDLQGQST--------------LKISNPKGWVTFEEEEDFGV 1445
+ A SS D + L + T + + +PK ++
Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572
Query: 1446 KGKSKSACSDLLGNQPSSFSGS----NLTLNDDWNKGTNVSFCVLPSRRPPPP---PVPL 1498
SK A S PS++ G+ L + + P+ PP P P
Sbjct: 1573 TPSSKEASSP-PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP 1631
Query: 1499 LPPG--TSPPVDPFTTLASKASP 1519
P G TSPPV P + S SP
Sbjct: 1632 APKGTPTSPPVTPSSLKDSPTSP 1654
Score = 89.0 bits (219), Expect = 3e-17
Identities = 74/275 (26%), Positives = 98/275 (35%), Gaps = 42/275 (15%)
Query: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLP---------------IRPSRA 1066
P + P S G+ P +P S P EGP P R + A
Sbjct: 867 PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926
Query: 1067 PSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPP------PPRPVAPPTRPAPPQR 1120
P P PS + +P P P+ PA P PK P PP P P P+P
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATP-SPKWAPTPPAATPPSPKGGPATPSPKGA 985
Query: 1121 PPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKT 1180
P PP+ + PSP+ G A P P G T PP +P + P + +
Sbjct: 986 PTPPAA-TPPSPKGGPATPSPKGAPTPPAVTPPSPK--GSPAATPFPKGASTPPAATPPS 1042
Query: 1181 SETSKGSTFLPE--PLKPQAAFPPQSSLP----------PPAQRLQEPLVPVAAPMPQSG 1228
+ S +T LP+ P P A P P PPA P A P P+
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGA 1102
Query: 1229 PQPNLETPPQP-----PPRSRSSHSLPSEASSQPQ 1258
P P TPP P P + + + P+ P+
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137
Score = 85.5 bits (210), Expect = 4e-16
Identities = 121/510 (23%), Positives = 173/510 (33%), Gaps = 67/510 (13%)
Query: 1027 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPA 1086
P+ + SP P T P+ P+P PS P P + +P
Sbjct: 1080 PTPPAATPPSPKGGPAT-----PSPKGAPMPPAATPPS--PKGGLATPPHKGAPTTPAAT 1132
Query: 1087 TPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSG------RSQPSPQAGLAGPG 1140
P P+ A P P + P P A P P PPP G + PSP+ GLA P
Sbjct: 1133 PPSPKGGLATP--PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 1141 PAGYSTARPTIPPR-AGVISAPQSHARASAGRLTPES--------QSKTSETSKGSTFLP 1191
P G T PP G ++ P + TP S K + T+ +T P
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-PP 1249
Query: 1192 EPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPS 1251
P A PP+ + PPA +A P + P P + TPP P +S P
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS---PP 1306
Query: 1252 EASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQL 1311
+ + P T G +P P + + T P TP K
Sbjct: 1307 KGAPTPPAATPPSPKGSPGTP----PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT 1362
Query: 1312 PSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFR 1371
PS+ + PT PP S + P+P G +P D T+ P
Sbjct: 1363 PSSKEG---------PT-PPAATPSHKGGPAMTPPSP-KRGPAIPSPKGDPTSPAVIPLS 1411
Query: 1372 AKSEESEATSWFSKEEPV--TISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKIS 1429
K + + P ++P P++ P+ K+ A+S+ G + +G TL
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTP-PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470
Query: 1430 NPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSR 1489
P +E K + S+ P+ L V+PS
Sbjct: 1471 TPP-----SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP-------------AVIPS- 1511
Query: 1490 RPPPPPVPLLPPGTSPPVDPFTTLASKASP 1519
P VP P P+ P TL SK +P
Sbjct: 1512 --SPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Score = 83.2 bits (204), Expect = 2e-15
Identities = 132/534 (24%), Positives = 182/534 (34%), Gaps = 73/534 (13%)
Query: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQS-PTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1080
P + P S G T P+++P + + P+ EGP P P+ PS GP SP
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP-----PAATPSHKGGPAMTPPSP 1389
Query: 1081 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP--APPQR----PP---PPSGRSQPS 1131
PA P P+ DP P P P P TR A P + PP P S + P+
Sbjct: 1390 -KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448
Query: 1132 ---PQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQ----------- 1177
P+ G A P G T PP AP+ A +S+ + P +
Sbjct: 1449 TSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508
Query: 1178 --SKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLET 1235
S E + +P+ P A S P +E L+P A +P P + T
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATL--LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPT 1566
Query: 1236 PPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSV 1295
P + P S EASS P V + L I P S +
Sbjct: 1567 PKEAPATPSSK-----EASSPPAVTPSTYKGAPSPKELLIPP--------AVTSPSPKEA 1613
Query: 1296 QTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTR 1355
T P TP PS + + PT PP+ S ++ +SP +
Sbjct: 1614 PTPPAVTP--------PSPEKGPATPAPKGTPTSPPVTP--SSLKDSPTSPASVTCKMGA 1663
Query: 1356 TNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFK 1415
T P A+ G P + + E I P+ + KS A+S
Sbjct: 1664 TVP----QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719
Query: 1416 DSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLT---LN 1472
S + L P + +++ KGK S P S + + LT
Sbjct: 1720 PSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFE 1779
Query: 1473 DDWNKGTNVSFCVLPSRRPP------PPPVPLLPPGTS-PPVDPFTTLASKASP 1519
K + S PS PP P PVP LPP P P L S + P
Sbjct: 1780 KVLPKPESASVSAAPS--PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKP 1831
Score = 80.9 bits (198), Expect = 9e-15
Identities = 114/475 (24%), Positives = 164/475 (34%), Gaps = 44/475 (9%)
Query: 1022 PQHLQPSSSSGLGTSP-SSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1080
P PS GL T P +P + P+ GP S P P PP+A
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS-------PPKGAPTPPAATPPS 1319
Query: 1081 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPG 1140
P TP P+ P P P P P T P+ P PS + P+P A A P
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA--ATPS 1377
Query: 1141 PAGYSTARPTIPPRAGVISAPQSHARASAG-RLTPESQSKTSETSKG-STFLPEPLKPQA 1198
G P P R I +P+ + A L+P+ T T +G +T L P A
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437
Query: 1199 AFP------PQSSLP-----PPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSH 1247
P P +S P P+ + L V P P+ P P + P+ +
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK-QVATSSSPKKAPAT 1496
Query: 1248 SLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVP----TP 1303
P A + P V + + + DP + L + A L+ + + +P P
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556
Query: 1304 DPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRT 1363
PK+ +P+ ++ S S + P PA + S SP + T+P
Sbjct: 1557 SPKKTPAIPTPKEAPATPS-SKEASSP--PAVTPSTYKGAPSPKELLIPPAVTSPSPKEA 1613
Query: 1364 AAP---GNPFRAKSEESEATSWFSKEEPVT--------ISPFPSLQPLGHNKSRASSSLD 1412
P P K + A PVT SP +G +AS L
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLP 1673
Query: 1413 GFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGS 1467
K L + L P+ G + K SA S + PS+ +GS
Sbjct: 1674 AKKGPTAL--KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGS 1726
Score = 80.1 bits (196), Expect = 2e-14
Identities = 82/344 (23%), Positives = 121/344 (35%), Gaps = 36/344 (10%)
Query: 1029 SSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATP 1088
S G T P+++P + T S P+ P +P P PS + +P P
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994
Query: 1089 LPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQP---SPQAGLAGPGPAGYS 1145
P+ PA P PK P P V PP+ P P P G S P +P + P
Sbjct: 995 SPKGGPATP-SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053
Query: 1146 TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPL---KPQAAFPP 1202
PT P A + +P+ + + P + T + KG P P P AA PP
Sbjct: 1054 KGAPTTP--AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
Query: 1203 QS----SLPP-------PAQRLQEPLVPVAAPMPQSGPQPNLETPPQ-------PPPRSR 1244
+ PP PA P +A P P+ P TPP PPP+
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171
Query: 1245 SSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPD 1304
+ + A++ P K + + +P LA + + T P
Sbjct: 1172 PT----TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1227
Query: 1305 PKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNP 1348
PK + PS + + + PP P + + +P P
Sbjct: 1228 PKGGLATPSPKGAPTTPAAT-----PPSPKGGPATPPPKGAPTP 1266
Score = 70.9 bits (172), Expect = 9e-12
Identities = 92/364 (25%), Positives = 129/364 (35%), Gaps = 62/364 (17%)
Query: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPT---ISEGPVPSLPIRPSRAPSRTPGPPSAQ- 1077
P+ S T+ S T SP+ +S P P P++ S P P
Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP--PTKKGSAGPDTPIGNL 824
Query: 1078 SSPIDAQPATPLPQKDPA------QPLEPKRPPPPRPVAPPTRPA-----------PPQR 1120
SSP+ A+ LP+ + P P PP P PT A PP+
Sbjct: 825 SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE 884
Query: 1121 PPPPSGRSQPSPQAGLAGPGP--AGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQS 1178
P PS + P P+ G A P P A + + P +A AP+ + + + P +
Sbjct: 885 TPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA 944
Query: 1179 KTSETSKGSTFLPEPL---KPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLET 1235
T + KG P P P AA PP P A P P+ P P T
Sbjct: 945 ATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP------------ATPSPKGAPTPPAAT 992
Query: 1236 PPQPP--PRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQL 1293
PP P P + S P+ + P + SP PF + A +
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTP--------PSPKGSP-AATPFPKGASTPPAATPP-- 1041
Query: 1294 SVQTSPVPTPDPKRLIQLPSATQSN-----VLSSVSCMPT----MPPIPARSQSQENMRS 1344
S + SP TP PK P+AT + S+ PT PP P + + +
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101
Query: 1345 SPNP 1348
+P P
Sbjct: 1102 APMP 1105
Score = 53.5 bits (127), Expect = 2e-06
Identities = 75/340 (22%), Positives = 115/340 (33%), Gaps = 71/340 (20%)
Query: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPI 1081
P + PS+ G SP SP+ E P P PS P + P P+ + +P
Sbjct: 1582 PPAVTPSTYKG-APSPKELLIPPAVTSPSPKEAPTPPAVTPPS--PEKGPATPAPKGTPT 1638
Query: 1082 DAQPATPLPQKD-PAQP-----------------LEPKRPPP--------PRPVAPPTRP 1115
+ P TP KD P P L K+ P P P + P
Sbjct: 1639 -SPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
Query: 1116 APPQRPPPPSGRSQ------PSPQAGLAGPGPAGYSTARPTIPPRA-------------- 1155
AP ++ P S P P A GP P +P +
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
Query: 1156 --GVISAPQSHAR-----ASAGRLTPESQSKT-SETSKGSTFLPEPLKPQAAFPPQSSLP 1207
G ++ P+S A A+ ++ P+ +S + S LP P PP+
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817
Query: 1208 PPAQRL-------------QEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEAS 1254
P + L ++ L+P+ P P SG P P + +P+ ++
Sbjct: 1818 PSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSA 1877
Query: 1255 SQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLS 1294
QP K N S + +S + E+ +AQL+
Sbjct: 1878 KQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLA 1917
Score = 51.2 bits (121), Expect = 7e-06
Identities = 95/414 (22%), Positives = 138/414 (33%), Gaps = 92/414 (22%)
Query: 1006 MEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSR 1065
M G+ + E+ LPQ P + + + P +S P P+LP
Sbjct: 1 MPGEATETVPATEQELPQ---PQAETAV------LPMSSALSVTAALGQPGPTLP----- 46
Query: 1066 APSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPS 1125
P +P P S + P P + PLE P A P AP
Sbjct: 47 -PPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP-------- 97
Query: 1126 GRSQPSPQAGLAGP--GPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSET 1183
P+ L GP PA + A P I P + P S A + L P S K+S
Sbjct: 98 --EAPTFLPNLIGPPISPAALALASPMIAPT--LKGTPSSSAPLALVALAPHSVQKSS-- 151
Query: 1184 SKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE--PLVPVAAPMPQSGPQPNL-ETPPQPP 1240
AFPP PP+ + E ++ ++AP+ S P+ NL + P +
Sbjct: 152 ---------------AFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVV 196
Query: 1241 PRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPV 1300
P + + S P S+ P + ++ Q V + P
Sbjct: 197 PNPKGTPSPPCIVSTVPY------------------------HCVTPMASIQSGVASLPQ 232
Query: 1301 PTPDPKRLIQLPSATQSNVLSSVSCMPTMPPI-----PARSQSQENMRSSPNPFITGLTR 1355
TP I P + +SSV P P P + ++ + P +T
Sbjct: 233 TTPTTTLAIASPQ-VKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS--- 288
Query: 1356 TNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPLGHNKSRASS 1409
S +TA P P S S P+ S F S+Q LG A S
Sbjct: 289 ----SQKTAGPNTP------PDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALS 332
Score = 50.1 bits (118), Expect = 2e-05
Identities = 126/505 (24%), Positives = 180/505 (35%), Gaps = 112/505 (22%)
Query: 1033 LGTSPSSSPRTSPCQSPTISEGPV----PSLPIRPSRAPSRTPGPPSAQSSPIDAQPATP 1088
+ +P+++ + C SP +S GP+ P+ P AP P + ++ + + P
Sbjct: 449 IAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPP 508
Query: 1089 LP------------------QKD--------------PAQP-LEPKRPPPPRPVAPPTRP 1115
LP QKD PAQ L K+ P V P +
Sbjct: 509 LPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDP---TVLPLVQA 565
Query: 1116 APPQRPPPPSGRSQP----SPQAGLA-----GPGPAGYSTARPTIP----PRAGVISAPQ 1162
AP P S S P SP+A LA P P G + T P A VI
Sbjct: 566 APKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDS 625
Query: 1163 SHARASAGRL------TPESQSKTSETSKGSTFLPEPLKPQAAFPPQS--------SLPP 1208
SAG L TP + E++ + P K + + + SL P
Sbjct: 626 YAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAP 685
Query: 1209 PAQRLQE------PLVPVA------APMPQS--GPQPNLETPPQPPPRSRSSHSLPSEAS 1254
++E PLVP A AP PQ+ P L P+ P+S S SLP +
Sbjct: 686 KNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE-IPKSVPSPSLPPAGT 744
Query: 1255 SQPQVKTNGISDGKRESPL----KIDPFEDLSFNLLAVSKAQLS-VQTSPVP-------- 1301
K +GIS +P+ K P ED + A SK L+ + SP P
Sbjct: 745 PPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804
Query: 1302 --TPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPF 1359
P K+ P N+ S VS + +P S S + + SP T +P
Sbjct: 805 TKRPPTKKGSAGPDTPIGNLSSPVSPVEA-SFLPENSLSFQGSKDSP-ATTHSPTPPSPK 862
Query: 1360 SDRTAAPGNPFRAKS-----EESEATSW----FSKEEPVTISPFP----SLQPLGHNKSR 1406
T + P K +E+ S F KE P T +P S+ K+R
Sbjct: 863 GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
Query: 1407 ASSSLDGFKDSFDLQGQSTLKISNP 1431
A+ + G S +G T + P
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATP 947
Score = 46.6 bits (109), Expect = 2e-04
Identities = 93/399 (23%), Positives = 140/399 (35%), Gaps = 57/399 (14%)
Query: 974 EEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSA--EVEELLPQHLQPSSSS 1031
++ L + A P + ST+ EV G E LP + P
Sbjct: 54 QQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPP--- 110
Query: 1032 GLGTSPSSSPRTSPCQSPTISEGPVPSLPIR-----PSRAPSRTPGPPSAQSSPID---A 1083
SP++ SP +PT+ P S P+ P + PP+ +SP A
Sbjct: 111 ---ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVA 167
Query: 1084 QPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAG 1143
+ + + P P EPK P + P P G PSP ++
Sbjct: 168 ESGSVITLSAPIAPSEPKTN---------LNKVPSEVVPNPKGT--PSPPCIVS---TVP 213
Query: 1144 YSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQ 1203
Y P ++GV S PQ+ + +P+ + T S+ L P P +
Sbjct: 214 YHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTI-----SSVLISPQNPGSLSLKG 268
Query: 1204 SSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNG 1263
PP A L +PV Q PN TPP P S SH P SS V+ G
Sbjct: 269 PVSPPAALSLSTQSLPVVT-SSQKTAGPN--TPPD-FPISLGSHLAPLHQSSFGSVQLLG 324
Query: 1264 ISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPD-----PKRLIQLPSATQS- 1317
+ S L + +S + + + S ++ P P P + P S
Sbjct: 325 QTG---PSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSV 381
Query: 1318 ----NVLSSVSCMPTMPPIPARSQSQEN-----MRSSPN 1347
+ +SS++C P+ A S S ++SSPN
Sbjct: 382 DKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPN 420
Score = 42.7 bits (99), Expect = 0.003
Identities = 154/633 (24%), Positives = 215/633 (33%), Gaps = 113/633 (17%)
Query: 944 LNVLSLNGKELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGED----AE 999
L+ S +LL +T AL P +K + + S S S L + A
Sbjct: 312 LHQSSFGSVQLLGQTGPSALSDPT-VKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPAT 370
Query: 1000 VAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTS--------------- 1044
VAA + VD + + + PS S + TS S SP TS
Sbjct: 371 VAAFPVVAPSVDKGPSTISSIT---CSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPL 427
Query: 1045 PCQSPTISEGPVPSLPIRP---SRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ----P 1097
Q P S G P + P + AP+ T + S P+ + P + + PA P
Sbjct: 428 VAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAP 487
Query: 1098 LEPKRPPPPRPVAPPTR-PAPPQRPPPPSGRSQPSP--------------QAGLAG---- 1138
+ PK P VA R P P P P ++ PS A L G
Sbjct: 488 VAPKEPSTQ--VATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS 545
Query: 1139 PGPAGYSTAR-PTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPE-PLKP 1196
P AG +T + PT+ P V +AP++ +P QS +S PE PL P
Sbjct: 546 PAQAGLTTKKDPTVLPL--VQAAPKN---------SPSFQSTSSS--------PEIPLSP 586
Query: 1197 QAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEA--- 1253
+A +S L EPL P+ P T P S S S A
Sbjct: 587 EATLAKKS--------LGEPL-PIGKPASSM-------TSPLGVNSSASVIKTDSYAGPD 630
Query: 1254 SSQPQVKTNGISDGKRESPLK-IDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLP 1312
S+ P +K++ I+ PL+ DP A + TS T L
Sbjct: 631 SAGPLLKSSLITPTVAAFPLESADP---------AGVAPTTAKGTSTYTTTASPFLEGTV 681
Query: 1313 SATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRA 1372
S N + T+P +P S EN +P+P T P + AP P
Sbjct: 682 SLAPKNHPVKEGTLTTLPLVPTAS---ENCPVAPSPQNT----CAPLATLVLAPEIPKSV 734
Query: 1373 KSEESEATSWFSKEEPVT-ISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNP 1431
S + V IS +L P+ + + G + +G T +P
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 1432 KGWVTFEEEEDFGVKGKSKSACSDL-LGNQPSSFS---GSNLTLNDDWNKGTNVSFCVLP 1487
+ K SA D +GN S S S L N +G+ S
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 1488 SRRPPPPPVPLLPPGTSPPVDPFTTLASKASPT 1520
S PP P P +P TL K +PT
Sbjct: 855 SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 90.1 bits (222), Expect = 1e-17
Identities = 108/424 (25%), Positives = 162/424 (38%), Gaps = 52/424 (12%)
Query: 1015 AEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGP--VPSLPIRPSRAPSRTPG 1072
A + E +P L P S L P SP + P ++ +S P +P+ P+ + SR P
Sbjct: 432 APLNEEMPL-LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSR-PL 489
Query: 1073 PPSAQSSPIDAQPATPLPQKDPAQPLE--PKRPP---PP-----RPVAPPTRPAP----- 1117
S S P + P +P P+ P PLE P PP PP P++PP +P
Sbjct: 490 EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549
Query: 1118 ---PQRPPPPSGRSQPSPQAGLAGPGPAGYSTARP------TIPPRAGVISAPQSHARAS 1168
P PPP + P P+A P P + P + PP A + P + S
Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLS 609
Query: 1169 AGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQS---SLPPPAQRLQE-PLVPVAAPM 1224
P +S S + S P P + PP+ S PP RL P+V +P
Sbjct: 610 ----PPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPP 665
Query: 1225 PQSGP--QPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRES----PLKIDPF 1278
P+ P P E+P PPP + P ++ + P + + S +S PL+ P
Sbjct: 666 PEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL 725
Query: 1279 EDLSFNLLAVSKAQLSVQTSPVP-----TPDPKRLIQLPSATQSNVLSSVS--CMPTMPP 1331
L +++ SP P +P P+ P A + ++ C+ +P
Sbjct: 726 LPLPEEPQLCPRSE-GPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPE 784
Query: 1332 IPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTI 1391
P S E SP P L+ + P P S + E + + E +
Sbjct: 785 EPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEP--CLSPQPEESHLSPQSEEPCL 842
Query: 1392 SPFP 1395
SP P
Sbjct: 843 SPRP 846
Score = 75.9 bits (185), Expect = 3e-13
Identities = 87/323 (26%), Positives = 120/323 (37%), Gaps = 44/323 (13%)
Query: 1016 EVEELLPQ----HLQPSSSSGLGTSPSSSPRTSPC-QSPTISEGPVPSLPIRPSRAPSRT 1070
E L PQ HL P + + P SP + P +S P S S P +
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843
Query: 1071 PGPPSAQSSP-IDAQPATPLPQKDPAQPLEPKRP------PPP---------------RP 1108
P P + SP ++ P +P P+K P +P + P PPP P
Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP 903
Query: 1109 VAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS 1168
PP P P + P PSG SPQ P P S P A + +
Sbjct: 904 GEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGA 963
Query: 1169 AGRLTPES-------QSKTSETSKGSTFLPEPLKPQAAFP-PQSSLPPPAQRLQEPLVPV 1220
G PES ++ S + + PEP+ P P P S + P + L EPL P
Sbjct: 964 KGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQ 1023
Query: 1221 AAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFED 1280
+P+ Q P P Q P + S+PS S P K G+SD ++ + +
Sbjct: 1024 CSPLLQHSLVPQNSPPSQCSPPALPL-SVPSPLS--PIGKVVGVSDEAELHEMETEKVSE 1080
Query: 1281 LSFNLLAVSKAQLSVQTSPVPTP 1303
L S TSP+P+P
Sbjct: 1081 PECPALEPS------ATSPLPSP 1097
Score = 72.8 bits (177), Expect = 2e-12
Identities = 90/356 (25%), Positives = 129/356 (36%), Gaps = 64/356 (17%)
Query: 1069 RTPGPPSAQSSPI----------------DAQPATPLPQKDPAQPLEPKRPPPPRPVAPP 1112
+ PGP ++ P+ + P P P++ P P PP P +
Sbjct: 407 KEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSP-----PPEESPTS-- 459
Query: 1113 TRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARP------TIPPRAGVISAPQSHAR 1166
PPP + R P P+ A P P +RP + PP +S P +
Sbjct: 460 --------PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSP 511
Query: 1167 ASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS-LPPPAQRLQEPLVPVAAPMP 1225
S ES E S S L PL P PP++S L PP + + PL P +P
Sbjct: 512 FSP---LEESPLSPPEESPPSPALETPLSP----PPEASPLSPPFE--ESPLSPPPEELP 562
Query: 1226 QSGP------QPNLETPPQPPPRSRSSHSLPSEASSQ-PQVKTNGISDGKRESPLKIDPF 1278
S P P E P PP S S P EAS P + + +S ESPL P
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP- 621
Query: 1279 EDLSFNLLAVSKAQLSVQTSPV-PTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQ 1337
S+ + SP+ P P+ + P ++ + L VS + P S
Sbjct: 622 --------EASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673
Query: 1338 SQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISP 1393
E +SP P + L+ S + P + + E S +E P+ P
Sbjct: 674 PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
Score = 64.3 bits (155), Expect = 9e-10
Identities = 134/519 (25%), Positives = 185/519 (35%), Gaps = 95/519 (18%)
Query: 1020 LLPQHLQPSSSSGLGTSPSSSPR-------TSPCQSPTISEGPVP-------SLPIR--P 1063
L PQ +P + L SP S P T P P ++ P P +LP R P
Sbjct: 2347 LRPQ--EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLP 2404
Query: 1064 SRAPSRTPGPPSAQSS---PIDAQPAT-----PLPQKDPAQPLEPKRPPPPRPVAPPTRP 1115
S SR P P +QSS P+ +P + P P Q +P PP RP + P
Sbjct: 2405 SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS--RDP 2462
Query: 1116 APPQRPPPPSGRSQPSPQAGLAGP------GPAGYSTARPTIPPRAGVISAPQSHARASA 1169
P PP R QP A AG G G+ A P P A + HA+ +
Sbjct: 2463 FAPLHKPP---RPQPPEVAFKAGSLAHTSLGAGGFPAALPAGP-------AGELHAKVPS 2512
Query: 1170 GRLTPESQSKTSETSKGSTFLPEPLK---PQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQ 1226
G+ +S + G+ P P++ PQA P SL PP Q L P
Sbjct: 2513 GQPPNFVRSPGTGAFVGT---PSPMRFTFPQAVGEP--SLKPPVP--QPGLPPPHGINSH 2565
Query: 1227 SGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLK-----IDPFEDL 1281
GP P L P + + PS + P + G S G SPL+ P D
Sbjct: 2566 FGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGL--SPLRPPSVLPPPAPDG 2623
Query: 1282 SFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPP-IPARSQSQ- 1339
S L+ +Q S TSPV + P + L++ T P + SQ++
Sbjct: 2624 SLPYLSHGASQRSGITSPVEKRED------PGTGMGSSLATAELPGTQDPGMSGLSQTEL 2677
Query: 1340 ENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQP 1399
E R R R N R + E + A + + P + PS P
Sbjct: 2678 EKQRQR--------QRLRELLIRQQIQRNTLRQEKETAAAAAG-AVGPPGSWGAEPS-SP 2727
Query: 1400 LGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLLGN 1459
SR + G +D L G K+S P + G D L
Sbjct: 2728 AFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGP-------------ILGPGSFPSDDRLSR 2774
Query: 1460 QPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPL 1498
P + S++ +N G + +F R P P +PL
Sbjct: 2775 PPPPATPSSMDVNSRQLVGGSQAFY---QRAPYPGSLPL 2810
Score = 62.8 bits (151), Expect = 2e-09
Identities = 75/287 (26%), Positives = 94/287 (32%), Gaps = 55/287 (19%)
Query: 1037 PSSSPRTSPCQSPTISEGPVPSLPIRPS--RAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1094
P P P Q P G P+ P+ P AP P PS +P +
Sbjct: 2164 PPQVPAQVPSQDPF---GLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA 2220
Query: 1095 AQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPG--------PAGYST 1146
QP E PP P P+ P P +P PS + P++ G G P +
Sbjct: 2221 GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280
Query: 1147 ARPTI---------------PPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLP 1191
+R + PP G + +P S L K T + S
Sbjct: 2281 SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQV-- 2338
Query: 1192 EPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGP-------------QPNLETPPQ 1238
EP P PQ PPPAQ L AP P S P QP L PQ
Sbjct: 2339 EPQSPGLGLRPQE--PPPAQAL--------APSPPSHPDIFRPGSYTDPYAQPPLTPRPQ 2388
Query: 1239 PPPRSRSSHSLPSEASSQP--QVKTNGISDGKRESPLKIDPFEDLSF 1283
PPP P S P +V + S +SPL P +F
Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAF 2435
Score = 61.2 bits (147), Expect = 7e-09
Identities = 113/493 (22%), Positives = 166/493 (33%), Gaps = 117/493 (23%)
Query: 1024 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP--GPPSA----- 1076
+L S G+G +S P SP P E +L ++ + +P GPP+
Sbjct: 2254 NLAVPESPGVGGGKASEPLLSP---PPFGESR-KALEVKKEELGASSPSYGPPNLGFVDS 2309
Query: 1077 ------------QSSPIDAQPATP-LPQKDPAQP---LEPKRPPPPRPVAP--PTRP--- 1115
++ + P TP Q +P P L P+ PPP + +AP P+ P
Sbjct: 2310 PSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIF 2369
Query: 1116 -----APPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAG 1170
P PP + R QP P P + P + V ++PQS + +S
Sbjct: 2370 RPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPS-----DPFSRVPASPQSQS-SSQS 2423
Query: 1171 RLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQ 1230
LTP S F P P+ P+ P S PP + ++P P
Sbjct: 2424 PLTPRPLS-------AEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAP----------- 2465
Query: 1231 PNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSK 1290
L PP+P P P A + + G + L P +L +K
Sbjct: 2466 --LHKPPRPQP--------PEVAFKAGSLAHTSLGAGGFPAALPAGPAGELH------AK 2509
Query: 1291 AQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQE---NMRSSPN 1347
+ V +P + PS + +V PP+P N P
Sbjct: 2510 VPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPG 2569
Query: 1348 PFITGLTRTNPFSDRTAAPGN------PFRAKSEESEATSWFSKEEPVTISPFP----SL 1397
P + TN T A GN P S + + S P ++ P P SL
Sbjct: 2570 PTLGKPQSTN----YTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSL 2625
Query: 1398 QPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDLL 1457
L H S+ S I++P E+ ED G S A ++L
Sbjct: 2626 PYLSHGASQRSG------------------ITSP-----VEKREDPGTGMGSSLATAELP 2662
Query: 1458 GNQPSSFSGSNLT 1470
G Q SG + T
Sbjct: 2663 GTQDPGMSGLSQT 2675
Score = 53.9 bits (128), Expect = 1e-06
Identities = 59/221 (26%), Positives = 83/221 (37%), Gaps = 25/221 (11%)
Query: 1042 RTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEP- 1100
+T P Q P P+ L + G P Q+ P+ A P PQ P P P
Sbjct: 4239 QTPPYQEPGTQTSPLQGL----LGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPG 4294
Query: 1101 --KRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIP-PRAGV 1157
P PV P P+ PQ P PS PS Q P A P P P+
Sbjct: 4295 ALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL----PTEAQLPPTHPGTPKPQGPT 4350
Query: 1158 ISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL-PPPAQRLQEP 1216
+ P +A +L SK L E KP+ QSSL P ++
Sbjct: 4351 LEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE-----QSSLVPGHLDQVNGQ 4405
Query: 1217 LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQP 1257
+VP A+ Q +++ P+ P + + S+ EA+ +P
Sbjct: 4406 VVPEAS-------QLSIKQEPREEPCALGAQSVKREANGEP 4439
Score = 45.1 bits (105), Expect = 5e-04
Identities = 35/123 (28%), Positives = 50/123 (40%), Gaps = 5/123 (4%)
Query: 1012 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRP-SRAPSRT 1070
D+ + + +LP + S L SP P + + V +L +R S P
Sbjct: 4855 DWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYN-VSNLDVRQLSAPPPEE 4913
Query: 1071 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVA---PPTRPAPPQRPPPPSGR 1127
P PP + +P A P T + P +PL P P P+A RP P RPP
Sbjct: 4914 PSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGED 4973
Query: 1128 SQP 1130
S+P
Sbjct: 4974 SRP 4976
Score = 39.3 bits (90), Expect = 0.029
Identities = 109/453 (24%), Positives = 147/453 (32%), Gaps = 85/453 (18%)
Query: 1024 HLQ-PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPID 1082
HL+ P LG+ P ++ T SPT G S PGP S +
Sbjct: 2103 HLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLK 2162
Query: 1083 AQPATP--LPQKDP-----AQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAG 1135
P P +P +DP A PLEP+ P APP PP PS
Sbjct: 2163 LPPQVPAQVPSQDPFGLAPAYPLEPRFPT-----------APPTYPPYPS---------- 2201
Query: 1136 LAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEP-L 1194
P G P PP G S P AG+ E + T + P+P L
Sbjct: 2202 -----PTGA----PAQPPMLGASSRP------GAGQ-PGEFHTTPPGTPRHQPSTPDPFL 2245
Query: 1195 KPQA------AFPPQSSL-----------PPP----AQRLQEPLVPVAAPMPQSGPQPNL 1233
KP+ A P + PPP + L+ + A P GP PNL
Sbjct: 2246 KPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGP-PNL 2304
Query: 1234 ETPPQPPPRSRSSHSLPSEASSQPQVK---TNGISDGKRESP-LKIDPFEDLSFNLLAVS 1289
P S +H E + K T S + +SP L + P E LA S
Sbjct: 2305 GFVDSP---SSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPS 2361
Query: 1290 KAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMP--TMPP-----IPARSQSQENM 1342
P DP L Q S +P ++P +PA QSQ +
Sbjct: 2362 PPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSS 2421
Query: 1343 RS--SPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQPL 1400
+S +P P +P + R +P R S + +P P P +
Sbjct: 2422 QSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQP-PEVAFK 2480
Query: 1401 GHNKSRASSSLDGFKDSFDLQGQSTLKISNPKG 1433
+ + S GF + L P G
Sbjct: 2481 AGSLAHTSLGAGGFPAALPAGPAGELHAKVPSG 2513
Score = 38.9 bits (89), Expect = 0.038
Identities = 65/257 (25%), Positives = 93/257 (36%), Gaps = 40/257 (15%)
Query: 1037 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPID---AQPATPL---P 1090
PSS P + P + V L + + S+++S + AQP+ L P
Sbjct: 4086 PSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQP 4145
Query: 1091 QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP-PSGRSQPS----PQAGLAGPGPAGYS 1145
L P++P RP+ T P PP+ P SG+ P P G G
Sbjct: 4146 GSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVL 4205
Query: 1146 TARPTI----PPRAGVISA---PQSHARASAGRLTPESQSKTSETSKGSTFL---PE--- 1192
P + P + + A + ++ A R TP Q ++TS L P+
Sbjct: 4206 AKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGG 4265
Query: 1193 -------PLK-----PQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPP 1240
PL+ P+ PP+ PP A L PV P S PQ P +P
Sbjct: 4266 FPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQ----EPKRPS 4321
Query: 1241 PRSRSSHSLPSEASSQP 1257
S LP+EA P
Sbjct: 4322 QLPSPSSQLPTEAQLPP 4338
Score = 38.1 bits (87), Expect = 0.066
Identities = 74/318 (23%), Positives = 102/318 (32%), Gaps = 32/318 (10%)
Query: 1203 QSSLPPPAQRLQEPLVPVAAPM-PQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKT 1261
Q P P Q +PL + PQ N E P PPP P E+ + P +
Sbjct: 405 QPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEA 464
Query: 1262 NGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLS 1321
+ +S E P P L +S+ SP P P L +S+ S
Sbjct: 465 SRLSPPPEELPASPLP------EALHLSRPLEESPLSPPPEESP-----LSPPPESSPFS 513
Query: 1322 SVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATS 1381
+ P PP + SP P + L + PF + +P S EA+
Sbjct: 514 PLEESPLSPPEESPPSPALETPLSPPPEASPL--SPPFEESPLSPPPEELPTSPPPEASR 571
Query: 1382 WFSKEEPVTISPFPSLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEE 1441
E +SP P P+ AS F++S +S P EE
Sbjct: 572 LSPPPEESPMSPPPEESPMS-PPPEASRLFPPFEES---------PLSPP-------PEE 614
Query: 1442 DFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPP 1501
S S + P S ++ V+ PPP PL PP
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
Query: 1502 GTSPPVDPFTTLASKASP 1519
P P AS+ SP
Sbjct: 675 PEESPTSP-PPEASRLSP 691
Score = 36.2 bits (82), Expect = 0.25
Identities = 31/102 (30%), Positives = 40/102 (39%), Gaps = 16/102 (15%)
Query: 1068 SRTPGPPSAQS-----SPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1122
S P PP+ S S +D + + P P +P P P P P +PPT P
Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPP---PEEPSPPPSPLAPSPASPPTEPLVELPTE 4939
Query: 1123 PPSGRSQPSPQAGLAGPGPAGYSTARP---TIPPRAGVISAP 1161
P + PSP + P +ARP PP G S P
Sbjct: 4940 PLAEPPVPSPLPLASSP-----ESARPKPRARPPEEGEDSRP 4976
Score = 35.4 bits (80), Expect = 0.43
Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 8/113 (7%)
Query: 1174 PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNL 1233
PE ++ S T S ++ +A PP+ PPP+ P P P+ + +P L
Sbjct: 4886 PEPPTQHSYTYNVSNL---DVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEP-L 4941
Query: 1234 ETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLL 1286
PP P P +S S S++P+ + +G+ P ++ ++ + + L
Sbjct: 4942 AEPPVPSPLPLAS----SPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKRL 4990
Score = 33.9 bits (76), Expect = 1.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 1487 PSRRPPPPPVPLLPPGTSPPVDPFTTLASK 1516
P P PPP PL P SPP +P L ++
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTE 4939
Score = 33.1 bits (74), Expect = 2.1
Identities = 26/70 (37%), Positives = 30/70 (42%), Gaps = 8/70 (11%)
Query: 1036 SPSSSPRT-SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1094
SP SP SP PT P+ LP P P P P SSP + A P P+ P
Sbjct: 4915 SPPPSPLAPSPASPPT---EPLVELPTEPLAEPP-VPSPLPLASSP---ESARPKPRARP 4967
Query: 1095 AQPLEPKRPP 1104
+ E RPP
Sbjct: 4968 PEEGEDSRPP 4977
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 90.1 bits (222), Expect = 1e-17
Identities = 104/413 (25%), Positives = 143/413 (34%), Gaps = 58/413 (14%)
Query: 1014 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS-RAPSRTPG 1072
S+ + E H S S T P+ R+ S SE + S +A +
Sbjct: 540 SSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMN 599
Query: 1073 PP-SAQSSPIDAQP--ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQ 1129
P ++ P+ QP TP P+ PL P PPPP P PP PPPP SQ
Sbjct: 600 RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP-------PPPPPLPSQ 652
Query: 1130 PSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTF 1189
+P AG A P YST I+ Q+ ++ S P + S
Sbjct: 653 SAPSAGSAAPMFVKYST-----------ITRLQNASQHSGALFKPPTPPVMQSQS----- 696
Query: 1190 LPEPLKPQAAFPPQSSLPPPAQRLQEPL----------VPVAAPMPQ-SGPQPNLE---- 1234
+KPQ PP +PPP P P A +PQ S P P L+
Sbjct: 697 ----VKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV 752
Query: 1235 ------TPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAV 1288
PP PPP LP +A +P V + K +P+ +
Sbjct: 753 QHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP 812
Query: 1289 SKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPNP 1348
+K Q + S +P P + +P T S + P P P S ++ P P
Sbjct: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872
Query: 1349 FITGLTRTNPFSDRTA--APGNPFRAKSEESEATSWFSKEEPVTISPFPSLQP 1399
+ P A AP +P K++ W PV FP P
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAK----PKWQPSSIPVPSPDFPPPPP 921
Score = 72.4 bits (176), Expect = 3e-12
Identities = 87/337 (25%), Positives = 131/337 (38%), Gaps = 62/337 (18%)
Query: 1037 PSSSPRTSPCQSPTISE-GPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPA 1095
P+ + S C P S PVPS+ + + P PP+ +S P+ PA PQ PA
Sbjct: 838 PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPA 897
Query: 1096 QPLEPK-------------RPPPPRP--VAPPTRPAP-----PQRPPPPSGRSQPSPQAG 1135
+PK PPPP V PP P+P P PPPP+ + P+P
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP--PPPPT--ASPTPDKS 953
Query: 1136 LAGPGPAGYSTARPTIPPRAGVISAPQ--SHARASAGRLTPESQSKTSETSKGSTFLPEP 1193
G G T++ + P PQ S ++S+G PE + + S S S F P
Sbjct: 954 ----GSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPK-RPSVDSLVSKFTP-- 1006
Query: 1194 LKPQAAFPPQSSLPPPAQR----------------LQEPLVPVAAPMPQSGPQPNLETPP 1237
++ P + +LPPPA LQ+ V AP+ + ++ P
Sbjct: 1007 -PAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFP 1065
Query: 1238 QPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQT 1297
PP S P P ++ + G + + N +++SV+
Sbjct: 1066 SPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV-------VNPQPQQWSKMSVKK 1118
Query: 1298 SPVPT----PDPKRLIQLPSATQSNVLSSVSCMPTMP 1330
+P PT D RL Q + Q + + V +PT P
Sbjct: 1119 APPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155
Score = 63.5 bits (153), Expect = 1e-09
Identities = 59/226 (26%), Positives = 82/226 (36%), Gaps = 26/226 (11%)
Query: 1060 PIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTR----- 1114
P P P P PP A P+ PA P K A + PP P P PP +
Sbjct: 761 PTPPPPPPIPAPLPPQAPPKPLVTIPA-PTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819
Query: 1115 ------PAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS 1168
P+PP P P + P Q+ A P P+ S + A P +
Sbjct: 820 PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME 879
Query: 1169 AGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSG 1228
+ L P + ++ P +K + + P SS+P P+ P + P
Sbjct: 880 SQPLKPVPANVAPQS-------PPAVKAKPKWQP-SSIPVPSPDFPPPPPESSLVFPPPP 931
Query: 1229 PQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISD--GKRESP 1272
P P PP PPP + S + S P KT+ S GK+ P
Sbjct: 932 PSPVPAPPPPPPPTA----SPTPDKSGSPGKKTSKTSSPGGKKPPP 973
Score = 60.5 bits (145), Expect = 1e-08
Identities = 64/239 (26%), Positives = 94/239 (39%), Gaps = 16/239 (6%)
Query: 1027 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPA 1086
P SS + P SP +P P + P P P + S+T P + P Q
Sbjct: 920 PPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKT-SSPGGKKPPPTPQRN 978
Query: 1087 TPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYST 1146
+ + A+ EPKRP V+ T PP PS + P P A P P +
Sbjct: 979 SSIKSSSGAEHPEPKRPSVDSLVSKFT---PPAESGSPSKETLPPP---AAPPKPGKLNL 1032
Query: 1147 ARPTIPP--RAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQS 1204
+ +P + G +SA A +GR +S + S F P P + + PP
Sbjct: 1033 SGVNLPGVLQQGCVSA---KAPVLSGR-GKDSVVEFPSPPSDSDFPPPPPETELPLPP-I 1087
Query: 1205 SLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQP--PPRSRSSHSLPSEASSQPQVKT 1261
+P P V V P PQ + +++ P P P R+ S+ +E S QP + T
Sbjct: 1088 EIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMAT 1146
Score = 31.6 bits (70), Expect = 6.1
Identities = 44/190 (23%), Positives = 66/190 (34%), Gaps = 24/190 (12%)
Query: 987 SSTSSTLLGEDAEVAADFDMEGDVDDYSA---EVEELLPQHLQPSSSSGLGTSPSSS--- 1040
S+ + L G + +F D+ E E LP P+ SG TSP +
Sbjct: 1047 SAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSG-NTSPKVAVVN 1105
Query: 1041 PRTSPCQSPTISEGPVPSLPIRP----------SRAPSRTPGPPSAQSSPIDAQPATPLP 1090
P+ ++ + P P+ P R S P+ P +SP + P
Sbjct: 1106 PQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGF 1165
Query: 1091 QKDPAQPLEPKRPPPPRPVAPPTRPAPPQR-------PPPPSGRSQPSPQAGLAGPGPAG 1143
D + L+ K ++ A P PPPP +AG G +G
Sbjct: 1166 LADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISG 1225
Query: 1144 YSTARPTIPP 1153
Y+T R PP
Sbjct: 1226 YATLRRGPPP 1235
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 87.4 bits (215), Expect = 9e-17
Identities = 100/339 (29%), Positives = 132/339 (38%), Gaps = 53/339 (15%)
Query: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPI 1081
PQ P + P SS SP +P+ S P PS P PS PPS ++ +
Sbjct: 274 PQVTPPRKDAAPALGPLSS---SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL 330
Query: 1082 DAQPATPLPQKDPAQPLEPKRPPPPR---PVAPPTRPAPPQRP--PPPSGRSQPSPQAGL 1136
+ P+ PL P PPP+ +A P APP P PP S + PSPQA
Sbjct: 331 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN 390
Query: 1137 AGPGPAGYSTARPTIPPRAGVISAPQSHARAS--AGRLTPESQSKTSETSKGSTFLPE-- 1192
A A + P PP + + AP S + + TP SQ+ S + P
Sbjct: 391 A---LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 447
Query: 1193 ---PLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGP---QPNLETPPQPPPRSRSS 1246
P+ P A PPQ+ PPP L P + +A P PQ+ P P L+ P PP
Sbjct: 448 ASPPMSPSATPPPQA--PPP---LAAPPLQLAKPPPQAPPALATPPLQALPSPPA----- 497
Query: 1247 HSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPV------ 1300
S P +A P S SPL P + + + S SP
Sbjct: 498 -SFPGQAPFSP-------SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 549
Query: 1301 -PTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQS 1338
PTP P + P T ++ P PP P+RS S
Sbjct: 550 PPTPGPDTSVSGPRLT-------LALAPGPPPPPSRSPS 581
Score = 82.4 bits (202), Expect = 3e-15
Identities = 129/530 (24%), Positives = 181/530 (34%), Gaps = 113/530 (21%)
Query: 1022 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP- 1080
P+ S+S T PS + R P + SL + S PSA+ +P
Sbjct: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 255
Query: 1081 IDAQPATPLPQKDPAQPLEPKRPPPPR-------------PVAPPTRPAPPQRPPPPSGR 1127
A P+ P P+ Q L P + PPR P+A P+ APP PPS +
Sbjct: 256 APAHPSQPKPK--GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313
Query: 1128 SQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGS 1187
+ PSP A P A S PT+ + +P A+ P + + + S
Sbjct: 314 TLPSPPA--TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 371
Query: 1188 TFLPEPLKPQAAFPPQSS------------LPPPAQRLQEPLVPVAAP-----------M 1224
PL P A PQ+ PPP+ +Q P P A+P
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 431
Query: 1225 PQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGK---------RESPLKI 1275
P S P L+ PP PP S S + P + + K PL+
Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491
Query: 1276 DPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR 1335
P SF A S+ SP+ TP P Q P + +L +PP P
Sbjct: 492 LPSPPASFPGQAPFSPSASLPMSPLATPPP----QAPPVLAAPLLQ-------VPPSPPA 540
Query: 1336 SQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFP 1395
S + + R P P + + P APG P P P
Sbjct: 541 SPTLQAPRRPPTPG-PDTSVSGPRLTLALAPGPP-----------------------PPP 576
Query: 1396 SLQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSD 1455
S P SS+L G DL G S+ S P+ ++ + G S ++
Sbjct: 577 SRSP--------SSTLSG----PDLAGHSSSATSTPEELRGYDSGPEGGA-AASPPPDAE 623
Query: 1456 LLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPVPLLPPGTSP 1505
L P++ W++G L R P P+P PP T P
Sbjct: 624 LAACHPAA-----------WSRGPAPP---LAFRGAPGAPLP-WPPATGP 658
Score = 67.0 bits (162), Expect = 1e-10
Identities = 75/248 (30%), Positives = 93/248 (37%), Gaps = 39/248 (15%)
Query: 1014 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGP 1073
S + L HL + S + P +P SP SP +S P PS A P
Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443
Query: 1074 PSAQSSPIDAQPATPLPQKDP---AQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQP 1130
PS +SP + ATP PQ P A PL+ +PPP APP PP ++ P
Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ---APPALATPPL-------QALP 493
Query: 1131 SPQAGLAGPGPAGYSTARP-----TIPPRA-GVISAPQSHARASAGRLTPESQSKTSETS 1184
SP A G P S + P T PP+A V++AP S
Sbjct: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS---------------P 538
Query: 1185 KGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSR 1244
S L P +P P S P RL L P P P P L + P S
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGP---RLTLALAPGPPPPPSRSPSSTL-SGPDLAGHSS 594
Query: 1245 SSHSLPSE 1252
S+ S P E
Sbjct: 595 SATSTPEE 602
Score = 64.7 bits (156), Expect = 7e-10
Identities = 84/341 (24%), Positives = 115/341 (33%), Gaps = 48/341 (14%)
Query: 1027 PSSSSGLGTSPSSSPRTSPCQSP-----TISEGPVPSLPIRPS-----------RAPSRT 1070
P+S G P+ + P SP T GP+ +R S AP R+
Sbjct: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145
Query: 1071 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQR---------- 1120
A+ P TP P PRP AP RP PP
Sbjct: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP-APSARPRPPTEGPRKSVSSAS 204
Query: 1121 -----PPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPE 1175
P P+ R +PS GL P A S + P + S P + A +
Sbjct: 205 EHSTTEPSPAARRRPSAGGGLQRP--ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 262
Query: 1176 SQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLET 1235
+ K + + P A P SS P P P A P Q+ P P T
Sbjct: 263 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP-AT 321
Query: 1236 PPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESP--LKIDPFEDLSFNLLAVSKAQL 1293
PP S S +L + S P + ++ ++P L + P L A
Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP-------LQAPPSPPA 374
Query: 1294 SVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPA 1334
S SP+ TP P Q P+A ++L + P PP+ A
Sbjct: 375 SPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPVQA 411
Score = 55.8 bits (133), Expect = 3e-07
Identities = 118/487 (24%), Positives = 165/487 (33%), Gaps = 99/487 (20%)
Query: 1064 SRAPSR-TPGPPSAQSSPIDAQPAT-----------PLPQKDPAQPLEPKRPPPPRPVAP 1111
+RAP TP PP + P PA P + A + P P A
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 1112 PTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR 1171
PTR + P P SGR + +P A PGP S R + R G + Q R SA
Sbjct: 79 PTRTSRP----PASGRGERAPPAKNTSPGPVS-SPGRASGTTRPGPLG--QKGLRISAEE 131
Query: 1172 LTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQP 1231
++ K +E K S + + P + P A+R + V P P +P
Sbjct: 132 TV--ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189
Query: 1232 NLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSKA 1291
P + P +S SS S S P + + G + P + L + +++
Sbjct: 190 --RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPARS 246
Query: 1292 QLSVQTSP-----VPTPDPKRLIQL-------PSATQSNVLSSVSCMPTMPPIPARSQSQ 1339
S + +P P PK L L P + L +S P P P+ S
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306
Query: 1340 E---NMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPS 1396
++++ P+P T P S T + G+P +AT F P P
Sbjct: 307 SAPPSLQTLPSPPAT------PPSQATTSLGSP------TLQATHSF--------LPSPP 346
Query: 1397 LQPLGHNKSRASSSLDGFKDSFDLQGQSTLKISNPKGWVTFEEEEDFGVKGKSKSACSDL 1456
L PL +A +L LQ + S P S L
Sbjct: 347 LSPLATPPPQAPPAL----ALPPLQAPPSPPASPP---------------------LSPL 381
Query: 1457 LGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPPPPPV--PLLPPGTSPPVDPFTTLA 1514
P + V P PP PPV P PP SPPV P T
Sbjct: 382 ATPSPQA------------PNALAVHLLQAPFSPPPSPPVQAPFSPP-ASPPVSPSATPP 428
Query: 1515 SKASPTL 1521
S+A P+L
Sbjct: 429 SQAPPSL 435
Score = 48.5 bits (114), Expect = 5e-05
Identities = 51/196 (26%), Positives = 74/196 (37%), Gaps = 31/196 (15%)
Query: 1028 SSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPAT 1087
S S+ L SP ++P P Q+P + P+ +P P PP++ + +P T
Sbjct: 506 SPSASLPMSPLATP---PPQAPPVLAAPLLQVP----------PSPPASPTLQAPRRPPT 552
Query: 1088 PLPQKDPAQP-----LEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPA 1142
P P + P L P PPPP T P S S P G GP
Sbjct: 553 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY-DSGPE 611
Query: 1143 GYSTARPTIPPRAGVIS----------APQSHARASAGRLTPESQSKTSETSKGSTFLPE 1192
G + A P PP A + + AP R + G P + ++ G + E
Sbjct: 612 GGAAASP--PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE 669
Query: 1193 PLKPQAAFPPQSSLPP 1208
P++A P +L P
Sbjct: 670 TEGPESATPAPGALDP 685
Score = 32.0 bits (71), Expect = 4.7
Identities = 44/169 (26%), Positives = 53/169 (31%), Gaps = 32/169 (18%)
Query: 988 STSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQ 1047
S SSTL G D + G ++ EEL P G SP + C
Sbjct: 579 SPSSTLSGPD--------LAGHSSSATSTPEELRGYDSGPEG--GAAASPPPDAELAACH 628
Query: 1048 SPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPR 1107
S GP P L R G P A P+ PAT D + P
Sbjct: 629 PAAWSRGPAPPLAFR---------GAPGA---PLPWPPATGPGSADGLCTIYETEGP--- 673
Query: 1108 PVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1156
PAP P PS P G A G +++R R G
Sbjct: 674 ---ESATPAPGALDPGPS----PGTSGGKAAAGAGAGASSRSPKQARLG 715
Score = 31.2 bits (69), Expect = 8.0
Identities = 54/228 (23%), Positives = 82/228 (35%), Gaps = 28/228 (12%)
Query: 1165 ARASAGRLTPESQSKTSETSK--GSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVA- 1221
A+A A TP +++ T + GS P P+ P A ++ + L E +
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 1222 APMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDG-KRESPLKIDPFED 1280
A +P+S P+ +PP R + P++ +S V + G + G R PL
Sbjct: 68 ATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 127
Query: 1281 LSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQE 1340
+ +A KA T PKR + LS+ + T P P
Sbjct: 128 SAEETVARGKA----------TEAPKR----------SALSAGARRDTSGPTPGTPSPAM 167
Query: 1341 NMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEP 1388
RS GL R P +A P P + + S S EP
Sbjct: 168 ARRSRAAGTEVGLPRPAP----SARPRPPTEGPRKSVSSASEHSTTEP 211
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 87.0 bits (214), Expect = 1e-16
Identities = 105/382 (27%), Positives = 139/382 (36%), Gaps = 74/382 (19%)
Query: 1005 DMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS---LPI 1061
D E D D SA+ + L Q + +G+ +PSS+P +P Q PT GP PS +P
Sbjct: 166 DNESDSDS-SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP-QLPT--PGPTPSATAVPP 221
Query: 1062 RPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP------ 1115
+ S S+ P P A ++P+ P P +P P PP P P PP +P
Sbjct: 222 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAG 280
Query: 1116 ---APPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARP-TIPPRAGVISAPQSHARASAGR 1171
AP PP G+ P P + AGP +P +PP+A AP + A+A
Sbjct: 281 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340
Query: 1172 LT----PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQS 1227
T P SQS QS PP ++PL P MP
Sbjct: 341 HTSLQLPASQSAL----------------------QSQQPP----REQPLPPAPLAMPHI 374
Query: 1228 GPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLA 1287
P P P P P+ +H P S N P + P LS +
Sbjct: 375 KPPPTTPIPQLPAPQ---AHKHPPHLSGPSPFSMN----ANLPPPPALKPLSSLSTH-HP 426
Query: 1288 VSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQSQENMRSSPN 1347
S +Q P P P Q P TQS +PP PA + +P
Sbjct: 427 PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ---------NLPPPPASHPPTGLHQVAPQ 477
Query: 1348 PFITGLTRTNPFSDRTAAPGNP 1369
P PF+ PG P
Sbjct: 478 P---------PFAQHPFVPGGP 490
Score = 66.2 bits (160), Expect = 2e-10
Identities = 82/283 (28%), Positives = 117/283 (41%), Gaps = 36/283 (12%)
Query: 1025 LQP-SSSSGLGTSPSSSPRTSPCQSP----TISEGPVPSLPIRPSR---APSRTPGPPSA 1076
LQP + S+G ++PS + Q P ++ GP+ P P P + G
Sbjct: 272 LQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPL 331
Query: 1077 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQ-PSPQAG 1135
+SP A P T L L+ ++PP +P+ P P +PPP + Q P+PQA
Sbjct: 332 GTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH 391
Query: 1136 -----LAGPGPAGYSTARPTIPPRAGVISAPQSHARASAG----RLTPESQSKTSETSK- 1185
L+GP P + P PP +S+ +H SA +L P+SQ S ++
Sbjct: 392 KHPPHLSGPSPFSMNANLPP-PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 450
Query: 1186 -GSTFLPEPLKPQAAFPPQS--SLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPP----- 1237
G T P A+ PP + P Q P VP P P+ TPP
Sbjct: 451 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGT 510
Query: 1238 -QPPPRSRSSHSLPSEA--SSQP----QVKTNGISDGKR-ESP 1272
PP S ++ S S A SS P Q+K + D + ESP
Sbjct: 511 SAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP 553
Score = 57.4 bits (137), Expect = 1e-07
Identities = 73/268 (27%), Positives = 102/268 (38%), Gaps = 46/268 (17%)
Query: 1022 PQHLQPSSSSG---LGTSPSSS-PRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1077
P L P +S G LGTSP+++ P TS + P ++ + P P PP+
Sbjct: 317 PFGLPPQASQGQAPLGTSPAAAYPHTS-------LQLPASQSALQSQQPPREQPLPPAPL 369
Query: 1078 SSP-IDAQPATPLPQKDPAQP--------------LEPKRPPPP--RPVAPPTRPAPPQR 1120
+ P I P TP+PQ Q + PPPP +P++ + PP
Sbjct: 370 AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 429
Query: 1121 PPPP---SGRSQPSPQAGLAGPGPAGYSTARP---TIPPRAGVISAPQ----SHARASAG 1170
PPP +SQP P + PG P + PP APQ H G
Sbjct: 430 HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 489
Query: 1171 R--LTPESQSKTSETSKGSTFLPEPLKPQAA-----FPPQSSLPPPAQRLQEPLVPVAAP 1223
+TP + TS G +P AA SS P P +++E + A
Sbjct: 490 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 549
Query: 1224 MPQSGPQPNLETPPQPPPRSRSSHSLPS 1251
P+S P P P+P SH+ S
Sbjct: 550 -PESPPPPPRSPSPEPTVVDTPSHASQS 576
Score = 34.7 bits (78), Expect = 0.73
Identities = 83/386 (21%), Positives = 138/386 (35%), Gaps = 76/386 (19%)
Query: 1159 SAPQSHARASAGRLTPESQSKTSETSKGSTFLP--EPLKPQAAFPPQSSLPPPAQRLQEP 1216
++P + S+GR +P + S +S SK T + +K +A+ P +S+ +R +E
Sbjct: 45 TSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSN-----KRQREK 99
Query: 1217 LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGK-------R 1269
VA+ ++ + +T Q R S E+S V G SD K
Sbjct: 100 ---VASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRS 156
Query: 1270 ESPLKIDPFEDLSFNLLAVSKAQLSVQ---------TSPVPTPDPKRLIQLPSATQSNVL 1320
SP P ++ S + + + L Q +P P+ P QLP T
Sbjct: 157 TSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP--TPGPTP 214
Query: 1321 SSVSCMPTMPPIPARSQSQENMRSSPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEAT 1380
S+ + P P +++ +Q ++P P T+ P P
Sbjct: 215 SATAVPPQGSPTASQAPNQPQAPTAPVP------HTHIQQAPALHPQRPP---------- 258
Query: 1381 SWFSKEEPVTISPFPSLQPLGHNKSRASSSL--------DGFKDSFDLQGQSTLKISNPK 1432
S P SP P LQPL + + S+ G LQ L+ P
Sbjct: 259 ---SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP 315
Query: 1433 GWVTFEEEEDFGVKGKSKSACSDLLGNQPSSFSGSNLTLNDDWNKGTNVSFCVLPSRRPP 1492
+ FG+ ++ + L + +++ ++L L S L S++PP
Sbjct: 316 --------QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLP--------ASQSALQSQQPP 359
Query: 1493 -----PPPVPLLPPGTSPPVDPFTTL 1513
PP +P PP P L
Sbjct: 360 REQPLPPAPLAMPHIKPPPTTPIPQL 385
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,256,078
Number of Sequences: 37866
Number of extensions: 4014955
Number of successful extensions: 84898
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 800
Number of HSP's successfully gapped in prelim test: 2487
Number of HSP's that attempted gapping in prelim test: 25498
Number of HSP's gapped (non-prelim): 26633
length of query: 1526
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1411
effective length of database: 13,892,928
effective search space: 19602921408
effective search space used: 19602921408
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.