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Search of human proteins with 237757308
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
(1350 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 2715 0.0
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 2703 0.0
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 2587 0.0
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 2478 0.0
gi|26190608 synaptojanin 2 [Homo sapiens] 1175 0.0
gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs... 211 3e-54
gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso... 206 1e-52
gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso... 206 1e-52
gi|190014578 suppressor of actin 1 [Homo sapiens] 203 8e-52
gi|7662414 inositol polyphosphate-5-phosphatase F [Homo sapiens] 192 2e-48
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ... 177 5e-44
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ... 177 5e-44
gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas... 162 3e-39
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 154 7e-37
gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] 135 2e-31
gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho... 133 1e-30
gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H... 125 3e-28
gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho... 125 3e-28
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 92 3e-18
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 92 3e-18
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 92 3e-18
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 92 3e-18
gi|163965366 nascent polypeptide-associated complex alpha subuni... 92 4e-18
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 90 2e-17
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 89 3e-17
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 89 3e-17
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 89 3e-17
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 89 3e-17
gi|150170670 piccolo isoform 2 [Homo sapiens] 88 5e-17
gi|150378539 piccolo isoform 1 [Homo sapiens] 88 5e-17
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 2715 bits (7038), Expect = 0.0
Identities = 1350/1350 (100%), Positives = 1350/1350 (100%)
Query: 1 MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI 60
MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI
Sbjct: 1 MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI 60
Query: 61 VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV 120
VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV
Sbjct: 61 VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV 120
Query: 121 TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL 180
TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL
Sbjct: 121 TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL 180
Query: 181 SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA 240
SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA
Sbjct: 181 SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA 240
Query: 241 CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG 300
CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG
Sbjct: 241 CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG 300
Query: 301 LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA 360
LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA
Sbjct: 301 LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA 360
Query: 361 SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT 420
SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT
Sbjct: 361 SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT 420
Query: 421 NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA 480
NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA
Sbjct: 421 NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA 480
Query: 481 GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS 540
GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS
Sbjct: 481 GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS 540
Query: 541 LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW 600
LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW
Sbjct: 541 LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW 600
Query: 601 LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR 660
LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR
Sbjct: 601 LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR 660
Query: 661 DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT 720
DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT
Sbjct: 661 DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT 720
Query: 721 SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE 780
SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE
Sbjct: 721 SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE 780
Query: 781 VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT 840
VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT
Sbjct: 781 VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT 840
Query: 841 PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP 900
PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP
Sbjct: 841 PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP 900
Query: 901 VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ 960
VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ
Sbjct: 901 VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ 960
Query: 961 FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM 1020
FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM
Sbjct: 961 FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM 1020
Query: 1021 SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS 1080
SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS
Sbjct: 1021 SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS 1080
Query: 1081 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ 1140
PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ
Sbjct: 1081 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ 1140
Query: 1141 PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP 1200
PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP
Sbjct: 1141 PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP 1200
Query: 1201 KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1260
KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP
Sbjct: 1201 KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1260
Query: 1261 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1320
ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE
Sbjct: 1261 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1320
Query: 1321 TPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1350
TPPQPPPRSRSSHSLPSEASSQPQQEQPSG
Sbjct: 1321 TPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1350
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 2703 bits (7006), Expect = 0.0
Identities = 1344/1344 (100%), Positives = 1344/1344 (100%)
Query: 1 MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI 60
MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI
Sbjct: 1 MRKRWACWSGSDAPGGCGGGCGRRRRRSRRKRAASEERRMAFSKGFRIYHKLDPPPFSLI 60
Query: 61 VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV 120
VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV
Sbjct: 61 VETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAYGLLGVLRLNLGDTMLHYLVLV 120
Query: 121 TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL 180
TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL
Sbjct: 121 TGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVRKVLNSGNFYFAWSASGISLDL 180
Query: 181 SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA 240
SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA
Sbjct: 181 SLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKA 240
Query: 241 CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG 300
CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG
Sbjct: 241 CLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPG 300
Query: 301 LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA 360
LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA
Sbjct: 301 LQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKA 360
Query: 361 SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT 420
SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT
Sbjct: 361 SEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRT 420
Query: 421 NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA 480
NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA
Sbjct: 421 NCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTRFQEVFRSMWSVNGDSISKIYA 480
Query: 481 GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS 540
GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS
Sbjct: 481 GTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDLADKARALLTTGS 540
Query: 541 LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW 600
LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW
Sbjct: 541 LRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDW 600
Query: 601 LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR 660
LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR
Sbjct: 601 LLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR 660
Query: 661 DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT 720
DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT
Sbjct: 661 DNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTT 720
Query: 721 SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE 780
SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE
Sbjct: 721 SLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHDYVFWCGDFNYRIDLPNEE 780
Query: 781 VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT 840
VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT
Sbjct: 781 VKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRT 840
Query: 841 PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP 900
PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP
Sbjct: 841 PAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRP 900
Query: 901 VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ 960
VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ
Sbjct: 901 VVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQ 960
Query: 961 FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM 1020
FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM
Sbjct: 961 FASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNLEEEM 1020
Query: 1021 SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS 1080
SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS
Sbjct: 1021 SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTS 1080
Query: 1081 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ 1140
PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ
Sbjct: 1081 PSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ 1140
Query: 1141 PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP 1200
PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP
Sbjct: 1141 PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAP 1200
Query: 1201 KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1260
KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP
Sbjct: 1201 KSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1260
Query: 1261 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1320
ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE
Sbjct: 1261 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1320
Query: 1321 TPPQPPPRSRSSHSLPSEASSQPQ 1344
TPPQPPPRSRSSHSLPSEASSQPQ
Sbjct: 1321 TPPQPPPRSRSSHSLPSEASSQPQ 1344
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 2587 bits (6706), Expect = 0.0
Identities = 1295/1311 (98%), Positives = 1295/1311 (98%), Gaps = 16/1311 (1%)
Query: 40 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 99
MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY
Sbjct: 1 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 60
Query: 100 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 159
GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR
Sbjct: 61 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 120
Query: 160 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 219
KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL
Sbjct: 121 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 180
Query: 220 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 279
RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD
Sbjct: 181 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 240
Query: 280 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 339
DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN
Sbjct: 241 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 300
Query: 340 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 399
LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD
Sbjct: 301 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 360
Query: 400 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 459
YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR
Sbjct: 361 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 420
Query: 460 FQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLL 519
FQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLL
Sbjct: 421 FQEVFRSMWSVNGDSISKIYAGTGALEGKAKLKDGARSVTRTIQNNFFDSSKQEAIDVLL 480
Query: 520 LGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTW 579
LGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTW
Sbjct: 481 LGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCVGTW 540
Query: 580 NVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNI 639
NVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNI
Sbjct: 541 NVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGNI 600
Query: 640 VSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKT 699
VSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKT
Sbjct: 601 VSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKT 660
Query: 700 GMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLF 759
GMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLF
Sbjct: 661 GMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLF 720
Query: 760 SHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTF 819
SHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTF
Sbjct: 721 SHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTF 780
Query: 820 APTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYT 879
APTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYT
Sbjct: 781 APTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYT 840
Query: 880 WTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSI 939
WTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSI
Sbjct: 841 WTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSI 900
Query: 940 KSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELL 999
KSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELL
Sbjct: 901 KSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELL 960
Query: 1000 NRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSA 1059
NRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSA
Sbjct: 961 NRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSA 1020
Query: 1060 EVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS 1119
EVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS
Sbjct: 1021 EVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS 1080
Query: 1120 AQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
AQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK
Sbjct: 1081 AQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRK 1140
Query: 1180 EFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPP 1239
EFG APKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPP
Sbjct: 1141 EFG----------------APKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPP 1184
Query: 1240 RAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL 1299
RAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL
Sbjct: 1185 RAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL 1244
Query: 1300 QEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1350
QEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPSG
Sbjct: 1245 QEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1295
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 2478 bits (6422), Expect = 0.0
Identities = 1251/1308 (95%), Positives = 1252/1308 (95%), Gaps = 53/1308 (4%)
Query: 40 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 99
MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY
Sbjct: 1 MAFSKGFRIYHKLDPPPFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDAY 60
Query: 100 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 159
GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR
Sbjct: 61 GLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEVR 120
Query: 160 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 219
KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL
Sbjct: 121 KVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTTDNRFFWNQSLHLHLKHYGVNCDDWLL 180
Query: 220 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 279
RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD
Sbjct: 181 RLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLD 240
Query: 280 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 339
DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN
Sbjct: 241 DSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVN 300
Query: 340 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 399
LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD
Sbjct: 301 LLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLD 360
Query: 400 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 459
YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR
Sbjct: 361 YGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQLVTR 420
Query: 460 FQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQEAID 516
FQEVFRSMWSVNGDSISKIYAGTGALEGKAK LKDGARSVTRTIQNNFFDSSKQEAID
Sbjct: 421 FQEVFRSMWSVNGDSISKIYAGTGALEGKAKAGKLKDGARSVTRTIQNNFFDSSKQEAID 480
Query: 517 VLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIRVCV 576
VLLLGNTLNSDLADKARALLTTGSLR ASSKVLKSMCENFYKYSKPKKIRVCV
Sbjct: 481 VLLLGNTLNSDLADKARALLTTGSLR--------ASSKVLKSMCENFYKYSKPKKIRVCV 532
Query: 577 GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA 636
GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA
Sbjct: 533 GTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNA 592
Query: 637 GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT 696
GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT
Sbjct: 593 GNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDT 652
Query: 697 VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR 756
VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR
Sbjct: 653 VKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR 712
Query: 757 MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK 816
MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK
Sbjct: 713 MLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGK 772
Query: 817 VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI 876
VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI
Sbjct: 773 VTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKI 832
Query: 877 LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL 936
LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL
Sbjct: 833 LYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVL 892
Query: 937 VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK 996
VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK
Sbjct: 893 VSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGK 952
Query: 997 ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD 1056
ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD
Sbjct: 953 ELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDD 1012
Query: 1057 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG 1116
YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG
Sbjct: 1013 YSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG 1072
Query: 1117 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAP 1176
PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSG P+P
Sbjct: 1073 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSP 1132
Query: 1177 TRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPT 1236
QAGLAGPGPAGYSTARPT
Sbjct: 1133 ------------------------------------------QAGLAGPGPAGYSTARPT 1150
Query: 1237 IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1296
IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA
Sbjct: 1151 IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1210
Query: 1297 QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1344
QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ
Sbjct: 1211 QRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQ 1258
>gi|26190608 synaptojanin 2 [Homo sapiens]
Length = 1496
Score = 1175 bits (3039), Expect = 0.0
Identities = 630/1349 (46%), Positives = 878/1349 (65%), Gaps = 81/1349 (6%)
Query: 40 MAFSKGFRIYHKLDPP-PFSLIVETRHKEECLMFESGAVAVLSSAEKEAIKGTYSKVLDA 98
MA SKG R+ +L S+++E R +++CL+FE+G VA L+ EKE IKG Y K+ DA
Sbjct: 1 MALSKGLRLLGRLGAEGDCSVLLEARGRDDCLLFEAGTVATLAPEEKEVIKGQYGKLTDA 60
Query: 99 YGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLRIDSSDEDRISEV 158
YG LG LRL G T L +LVLVTGC SVG+I ++E++++T+T+F L+ ++ +E+R+ +
Sbjct: 61 YGCLGELRLKSGGTSLSFLVLVTGCTSVGRIPDAEIYKITATDFYPLQEEAKEEERLIAL 120
Query: 159 RKVLNSGNFYFAWSASGISLDLSLNAHRSMQEQTT-DNRFFWNQSLHLHLKHYGVNCDDW 217
+K+L+SG FYF+W G DL++ + + + N FFWNQ LH+ L+ + V+C DW
Sbjct: 121 KKILSSGVFYFSWPNDGSRFDLTVRTQKQGDDSSEWGNSFFWNQLLHVPLRQHQVSCCDW 180
Query: 218 LLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDGHVANFVETEQVVY 277
LL+++CG V IRT+YA+HKQAKACL+SR+SCER GTRF+ RG NDDGHV+NFVETEQ++Y
Sbjct: 181 LLKIICGVVTIRTVYASHKQAKACLVSRVSCERTGTRFHTRGVNDDGHVSNFVETEQMIY 240
Query: 278 LDDSVSSFIQIRGSVPLFWEQPGLQVGSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQII 337
+DD VSSF+QIRGSVPLFWEQPGLQVGSH +R+ RG EANAPAFDRH LK YG+Q++
Sbjct: 241 MDDGVSSFVQIRGSVPLFWEQPGLQVGSHHLRLHRGLEANAPAFDRHMVLLKEQYGQQVV 300
Query: 338 VNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQ-K 396
VNLLGS+ GE +L++AF+ L AS HA D M+NFD+HQ KGGK EKL ++L+PQ++
Sbjct: 301 VNLLGSRGGEEVLNRAFKKLLWASCHAGDTPMINFDFHQFAKGGKLEKLETLLRPQLKLH 360
Query: 397 FLDYGFFYFNGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQL 456
+ D+ F + R Q GT+R NCLDCLDRTN+VQ+F+ LE+L QL+ LGL+ KP +
Sbjct: 361 WEDFDVFTKGENVSPRFQKGTLRMNCLDCLDRTNTVQSFIALEVLHLQLKTLGLSSKP-I 419
Query: 457 VTRFQEVFRSMWSVNGDSISKIYAGTGALEGKAK---LKDGARSVTRTIQNNFFDSSKQE 513
V RF E F++MWS+NG S+SK++ G+ ALEGKAK LKDGARS++RTIQ+NFFD KQE
Sbjct: 420 VDRFVESFKAMWSLNGHSLSKVFTGSRALEGKAKVGKLKDGARSMSRTIQSNFFDGVKQE 479
Query: 514 AIDVLLLGNTLNSDLADKARALLTTGSLRVSEQTLQSASSKVLKSMCENFYKYSKPKKIR 573
AI +LL+G+ ++ADK LL + +L V+ ++LK+M E +++ K+IR
Sbjct: 480 AIKLLLVGDVYGEEVADKGGMLLDSTALLVTP--------RILKAMTERQSEFTNFKRIR 531
Query: 574 VCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVE 633
+ +GTWNVNGGKQFRS + LTDWLLD+P+L+G + QD S P DIFA+GFEEMVE
Sbjct: 532 IAMGTWNVNGGKQFRSNVLRTAELTDWLLDSPQLSGATDSQDD-SSPADIFAVGFEEMVE 590
Query: 634 LNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVA 693
L+AGNIV+ASTTN+K+W +LQK ISR ++Y+LL S QLVGVCL++F+RP H PFIRDVA
Sbjct: 591 LSAGNIVNASTTNKKMWGEQLQKAISRSHRYILLTSAQLVGVCLYIFVRPYHVPFIRDVA 650
Query: 694 VDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSFP 753
+DTVKTGMGG GNKGAV IR FH+TS CF+CSH AGQSQVKERNED+ EI +KL FP
Sbjct: 651 IDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKERNEDYKEITQKLCFP 710
Query: 754 MGRMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFL 813
MGR +FSHDYVFWCGDFNYRIDL EEV +++Q+W L+ DQL QK++G++F+ F
Sbjct: 711 MGRNVFSHDYVFWCGDFNYRIDLTYEEVFYFVKRQDWKKLLEFDQLQLQKSSGKIFKDFH 770
Query: 814 EGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDE 873
EG + F PTYKYD+ S YDTS+KCRTPAWTDRVLW R+K PFD++A +L+LL++ +
Sbjct: 771 EGAINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRKKHPFDKTAGELNLLDSDLDVD 830
Query: 874 SKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDG 933
+K+ +TW+PG L +YGRAEL+ SDHRPV+A++++++ EV+ R+ +++EV + QGP D
Sbjct: 831 TKVRHTWSPGALQYYGRAELQASDHRPVLAIVEVEVQEVDVGARERVFQEVSSFQGPLDA 890
Query: 934 TVLVSIKS-SLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLS 992
TV+V+++S +L E N F + L EL+Q S+G ++L+R + +M VTF + SAL+VL
Sbjct: 891 TVVVNLQSPTLEEKNEFPEDLRTELMQTLGSYGTIVLVRINQGQMLVTFADSHSALSVLD 950
Query: 993 LNGKELLNRTITIALKSPDWIKNLEEEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEG 1052
++G ++ R + I K+ DW+K L EE+ ++ S+A S T+++ L E+ D E
Sbjct: 951 VDGMKVKGRAVKIRPKTKDWLKGLREEIIRKRDSMAPVSPTANSCLLEENFDFTSLDYES 1010
Query: 1053 DVDDYSAEVEELLPQHLQPS-SSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAP 1111
+ D + + L+ + QP S S LG +S+ P P+ PS++P
Sbjct: 1011 EGDILEDDEDYLVDEFNQPGVSDSELG-------------GDDLSDVPGPTALAPPSKSP 1057
Query: 1112 SRTPGPPSAQSSPIDAQPATPLPQKDPAQPL-EPKRPPPPRPVAPPTR---PAPPQRPPP 1167
+ T + P A + K + + E + P R ++ P R P PPQRPPP
Sbjct: 1058 ALT----KKKQHPTYKDDADLVELKRELEAVGEFRHRSPSRSLSVPNRPRPPQPPQRPPP 1113
Query: 1168 PSG---------ARSPAPTRKEFGGI-------GAPPSPGVARREMEAPKSPGTTRKDNI 1211
P+G A + T ++ + GAP P AR + P + + N
Sbjct: 1114 PTGLMVKKSASDASISSGTHGQYSILQTARLLPGAPQQPPKARTGISKPYNVKQIKTTNA 1173
Query: 1212 GRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS------AGRLTPESQSK 1265
++ + + L G A P S P+ A+ A L P
Sbjct: 1174 QEAEAAIRCLLEARGGASEEALSAVAPRDLEASSEPEPTPGAAKPETPQAPPLLPRRPPP 1233
Query: 1266 TSETSKGSTF--LPEPLKPQAAFPPQS---SLPPPAQRLQEPLVPVAAPMPQSGPQPNLE 1320
K T +PL P+ F Q+ ++ PP ++ P V V AP
Sbjct: 1234 RVPAIKKPTLRRTGKPLSPEEQFEQQTVHFTIGPPETSVEAPPV-VTAP----------R 1282
Query: 1321 TPPQPPPRSRSSHSLPSEASSQPQQEQPS 1349
PP P PR+ P +A+ +P +P+
Sbjct: 1283 VPPVPKPRTFQ----PGKAAERPSHRKPA 1307
Score = 35.0 bits (79), Expect = 0.49
Identities = 47/200 (23%), Positives = 66/200 (33%), Gaps = 47/200 (23%)
Query: 1085 PRTSPCQSPTISEGPVPSLP----IRPSRAPSR-TPGPPSAQSSPIDAQPATPLPQKDPA 1139
P TS P ++ VP +P +P +A R + P++ +P A + P P + P
Sbjct: 1268 PETSVEAPPVVTAPRVPPVPKPRTFQPGKAAERPSHRKPASDEAPPGAGASVPPPLEAP- 1326
Query: 1140 QPLEPKRPPPPRPVAPPT-------------------RPAPPQRPPPPSGARSPAPTRKE 1180
PL PK PP + AP P PP +G P
Sbjct: 1327 -PLVPKVPPRRKKSAPAAFHLQVLQSNSQLLQGLTYNSSDSPSGHPPAAGTVFPQGDFLS 1385
Query: 1181 FGGIGAPPSPGVARREMEA-----------------PKSPGTT----RKDNIGRSQPSPQ 1219
+P S G + EA PK T D + SP+
Sbjct: 1386 TSSATSPDSDGTKAMKPEAAPLLGDYQDPFWNLLHHPKLLNNTWLSKSSDPLDSGTRSPK 1445
Query: 1220 AGLAGPGPAGYSTARPTIPP 1239
P AG S A+ +PP
Sbjct: 1446 RDPIDPVSAGASAAKAELPP 1465
Score = 32.3 bits (72), Expect = 3.2
Identities = 50/240 (20%), Positives = 77/240 (32%), Gaps = 46/240 (19%)
Query: 1036 TLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTI 1095
T ++AE A +E + + P+ L+ SS +P ++ +P P +
Sbjct: 1170 TTNAQEAEAAIRCLLEARGGASEEALSAVAPRDLEASSEPE--PTPGAAKPETPQAPPLL 1227
Query: 1096 SEGPVPSLPIRPSRAPSRTPGPPSAQS---------------SPIDAQPATPLPQKDPA- 1139
P P +P RT P S + + ++A P P+ P
Sbjct: 1228 PRRPPPRVPAIKKPTLRRTGKPLSPEEQFEQQTVHFTIGPPETSVEAPPVVTAPRVPPVP 1287
Query: 1140 -----------------QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFG 1182
+P + PP PP APP P P P RK+
Sbjct: 1288 KPRTFQPGKAAERPSHRKPASDEAPPGAGASVPPPLEAPPLVPKVP-------PRRKK-- 1338
Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1242
AP + + + + G T + S P AG P ST+ T P G
Sbjct: 1339 --SAPAAFHLQVLQSNSQLLQGLTYNSSDSPSGHPPAAGTVFPQGDFLSTSSATSPDSDG 1396
>gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor
[Homo sapiens]
Length = 913
Score = 211 bits (538), Expect = 3e-54
Identities = 138/416 (33%), Positives = 214/416 (51%), Gaps = 63/416 (15%)
Query: 522 NTLNSDLADKARALLTTGSLRVSEQTLQSASSK--VLKS-MCENFYKYSKPKKIRVCVGT 578
N S++ D R+ T S + ++Q + ++KS + + Y+ + R GT
Sbjct: 212 NKSKSEITDMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGT 271
Query: 579 WNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFEEMVELNAGN 638
+NVNG + L WL + GIQ D++ +GF+E+ +L+
Sbjct: 272 YNVNGQSP-------KECLRLWLSN-----GIQA--------PDVYCVGFQEL-DLSKEA 310
Query: 639 IVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVK 698
T ++ W + + + D KY + +LVG+ L ++++ +HA +I +V +TV
Sbjct: 311 FFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVG 370
Query: 699 TGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIARKLSF------ 752
TG+ G GNKG VAIR FH TS+C V SH AA + + RN+D+ +I ++ F
Sbjct: 371 TGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPS 430
Query: 753 --PMGRMLFSHDYVFWCGDFNYRID-LPNEEVKELIRQQNWDSLIAGDQLINQKNAGQVF 809
P+ + +HD + W GD NYRI+ L E+VK+LI ++++ L A DQL Q A VF
Sbjct: 431 LPPL--TISNHDVILWLGDLNYRIEELDVEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVF 488
Query: 810 RGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNAS 869
GF EG++TF PTYKYD SDD+DTSEKCR PAW DR+LW+ + ++ S
Sbjct: 489 EGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGK-----------NITQLS 537
Query: 870 FQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQNIYKEVI 925
+Q LKTSDH+PV ++ DI + V E + +E++
Sbjct: 538 YQ-----------------SHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIV 576
>gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase
isoform b [Homo sapiens]
Length = 893
Score = 206 bits (524), Expect = 1e-52
Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 56/388 (14%)
Query: 565 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 624
+Y + R VGTWNVNG + L WL P P DI+
Sbjct: 233 EYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWLNCDPN-------------PPDIY 272
Query: 625 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 684
IGF+E+ +L+ + ++ W++ +++ + KY + +LVG+ L +F R
Sbjct: 273 CIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKD 331
Query: 685 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 744
+IRD+A +TV TG+ G GNKG VA+R +FH T+ C V SH AA + RN+D+
Sbjct: 332 QCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYK 391
Query: 745 EIARKLSFPMGRM------LFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGD 797
+I ++SF + + H+ V W GD NYR+ +P+ EVK LI +++ L+ D
Sbjct: 392 DICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFD 451
Query: 798 QLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFD 857
QL Q+ + F F EG++ F PTYKYD +D +D+S KCR PAW DR+LWR
Sbjct: 452 QLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWR------- 504
Query: 858 RSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEER 917
+++ LN + ELKTSDH+PV AL I + V+
Sbjct: 505 --GTNVNQLN-------------------YRSHMELKTSDHKPVSALFHIGVKVVDERRY 543
Query: 918 QNIYKEVIAVQGPPDGTVLVSIKSSLPE 945
+ ++++ + + + L S++ S E
Sbjct: 544 RKVFEDSVRIMDRMENDFLPSLELSRRE 571
>gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase
isoform a [Homo sapiens]
Length = 901
Score = 206 bits (524), Expect = 1e-52
Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 56/388 (14%)
Query: 565 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 624
+Y + R VGTWNVNG + L WL P P DI+
Sbjct: 233 EYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWLNCDPN-------------PPDIY 272
Query: 625 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 684
IGF+E+ +L+ + ++ W++ +++ + KY + +LVG+ L +F R
Sbjct: 273 CIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKD 331
Query: 685 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 744
+IRD+A +TV TG+ G GNKG VA+R +FH T+ C V SH AA + RN+D+
Sbjct: 332 QCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYK 391
Query: 745 EIARKLSFPMGRM------LFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGD 797
+I ++SF + + H+ V W GD NYR+ +P+ EVK LI +++ L+ D
Sbjct: 392 DICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFD 451
Query: 798 QLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFD 857
QL Q+ + F F EG++ F PTYKYD +D +D+S KCR PAW DR+LWR
Sbjct: 452 QLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWR------- 504
Query: 858 RSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEER 917
+++ LN + ELKTSDH+PV AL I + V+
Sbjct: 505 --GTNVNQLN-------------------YRSHMELKTSDHKPVSALFHIGVKVVDERRY 543
Query: 918 QNIYKEVIAVQGPPDGTVLVSIKSSLPE 945
+ ++++ + + + L S++ S E
Sbjct: 544 RKVFEDSVRIMDRMENDFLPSLELSRRE 571
>gi|190014578 suppressor of actin 1 [Homo sapiens]
Length = 587
Score = 203 bits (517), Expect = 8e-52
Identities = 147/454 (32%), Positives = 237/454 (52%), Gaps = 40/454 (8%)
Query: 99 YGLLGVLRLNLGDTMLHYLVLVTGCMSVGKIQESEVFRVTSTEFISLR------IDSSDE 152
+G+LG + L G+ YL+++T + VG+ V++ T + +S + D +
Sbjct: 58 FGILGTIHLVAGN----YLIVITKKIKVGEFFSHVVWKATDFDVLSYKKTMLHLTDIQLQ 113
Query: 153 DR---ISEVRKVLNSGNFYFAWSASGI-SLDLSLNAHRSMQEQT----TDNRFFWNQSLH 204
D ++ + VLN FYF+ + +L N QE + D RF WN L
Sbjct: 114 DNKTFLAMLNHVLNVDGFYFSTTYDLTHTLQRLSNTSPEFQEMSLLERADQRFVWNGHLL 173
Query: 205 LHLKHYGVNCDDWLLRLMCGGVEIRTIYAAHKQAKACLISRLSCERAGTRFNVRGTNDDG 264
L + L ++ G + + + K LISR SC RAG R+ VRG + +G
Sbjct: 174 RELSAQP-EVHRFALPVLHGFITMHSCSINGKYFDWILISRRSCFRAGVRYYVRGIDSEG 232
Query: 265 HVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQ-PGLQVGSHRVRMSRGFEANAPAFDR 323
H ANFVETEQ+V+ + S +SF+Q RGS+P+FW Q P L+ + + F R
Sbjct: 233 HAANFVETEQIVHYNGSKASFVQTRGSIPVFWSQRPNLKY--KPLPQISKVANHMDGFQR 290
Query: 324 HFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEHAADIQMVNFDYHQMVKGGKA 383
HF + +YGKQ+I+NL+ K E L + F + + +S + ++ + FD+H+ K +
Sbjct: 291 HFDSQVIIYGKQVIINLINQKGSEKPLEQTFAT-MVSSLGSGMMRYIAFDFHKECKNMRW 349
Query: 384 EKLHSVLKPQVQKFLDYGFFYF--NGSEVQRCQSGTVRTNCLDCLDRTNSVQAFLGLEML 441
++L S+L QV + D ++ + +V Q G R+NC+DCLDRTN +Q+ L L
Sbjct: 350 DRL-SILLDQVAEMQDELSYFLVDSAGQVVANQEGVFRSNCMDCLDRTNVIQSLLARRSL 408
Query: 442 AKQLEALG---LAEKPQLVTRFQEVFRSMWSVNGDSISKIYAGTGALE------GK---- 488
QL+ LG + +K + F++++++ W+ N ++ +K YAGTGAL+ GK
Sbjct: 409 QAQLQRLGVLHVGQKLEEQDEFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTHL 468
Query: 489 AKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGN 522
+ DG S+ R +NNF D +Q++ID L LGN
Sbjct: 469 GLIMDGWNSMIRYYKNNFSDGFRQDSID-LFLGN 501
>gi|7662414 inositol polyphosphate-5-phosphatase F [Homo sapiens]
Length = 1132
Score = 192 bits (487), Expect = 2e-48
Identities = 129/416 (31%), Positives = 208/416 (50%), Gaps = 53/416 (12%)
Query: 158 VRKVLNSGNFYFAWSASGISLDLSLNAHRSMQE--------QTTDNRFFWNQSLHLHLKH 209
++ ++S +FY++ ++ DL+ + R Q D+RFFWN+ + L
Sbjct: 167 LKMFMDSESFYYS-----LTYDLTNSVQRQSTGERDGRPLWQKVDDRFFWNKYMIQDLTE 221
Query: 210 YGV-NCDDWLLRLMCGGVEIRTIYA-------------------------AHKQAKACLI 243
G + D W++ ++ G V+I + H + LI
Sbjct: 222 IGTPDVDFWIIPMIQGFVQIEELVVNYTESSDDEKSSPETPPQESTCVDDIHPRFLVALI 281
Query: 244 SRLSCERAGTRFNVRGTNDDGHVANFVETEQVVYLDDSVSSFIQIRGSVPLFWEQPGLQV 303
SR S RAG R+ RG + +G+VAN+VETEQ++++ + SF+Q RGSVP+FW Q G +
Sbjct: 282 SRRSRHRAGMRYKRRGVDKNGNVANYVETEQLIHVHNHTLSFVQTRGSVPVFWSQVGYRY 341
Query: 304 GSHRVRMSRGFEANAPAFDRHFRTLKNLYGKQIIVNLLGSKEGEHMLSKAFQSHLKASEH 363
+ R R+ R + F HF N+Y KQ+I+NL+ E ++ A+ + +
Sbjct: 342 -NPRPRLDRSEKETVAYFCAHFEEQLNIYKKQVIINLVDQAGREKIIGDAYLKQVLLFNN 400
Query: 364 AADIQMVNFDYHQMVKGGKAEKLHSVLKPQVQKFLDYGFFYFNGSEVQRCQSGTVRTNCL 423
+ + V+FD+H+ +G K E + ++ LD + + + + V Q G R NC+
Sbjct: 401 -SHLTYVSFDFHEHCRGMKFENVQTLTDAIYDIILDMKWCWVDEAGVICKQEGIFRVNCM 459
Query: 424 DCLDRTNSVQAFLGLEMLAKQLEALGLAEKPQ-LVTRFQEVFRSMWSVNGDSISKIYAGT 482
DCLDRTN VQA + ++ +QL+ LG+ Q L + +++ MW+ NGDSIS+ YAGT
Sbjct: 460 DCLDRTNVVQAAIARVVMEQQLKKLGVMPPEQPLPVKCNRIYQIMWANNGDSISRQYAGT 519
Query: 483 GALEG----------KAKLKDGARSVTRTIQNNFFDSSKQEAIDVLLLGNTLNSDL 528
AL+G +KDG S R N F D+ +Q ID L+ G + DL
Sbjct: 520 AALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVID-LMQGIPVTEDL 574
>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
sapiens]
Length = 1188
Score = 177 bits (450), Expect = 5e-44
Identities = 205/830 (24%), Positives = 331/830 (39%), Gaps = 141/830 (16%)
Query: 554 KVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEF 613
++L+ M + +P I + +GTWN+ + I T W L K G
Sbjct: 385 QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKI-------TSWFLS--KGQGKTRD 435
Query: 614 QDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNK--YVLLASEQ 671
P DI+ IG +E ++K W L+ ++ + +A
Sbjct: 436 DSADYIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHT 483
Query: 672 LVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAA 731
L + + V +P+H I + D VKTG+ GNKGAV + +F+ TSL FV SH +
Sbjct: 484 LWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTS 543
Query: 732 GQSQVKERNEDFIEIARKLSF---PMGRMLFSH--DYVFWCGDFNYRIDLPN---EEVKE 783
G + RN++++ I R L+ + +H ++FW GD NYR+DLP E + +
Sbjct: 544 GSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQ 603
Query: 784 LIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD-LFSDDY------DTSE 836
I+QQ + L++ DQL+ ++ +VF F E ++TFAPTY+++ L D Y T
Sbjct: 604 KIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGM 663
Query: 837 KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTS 896
K P+W DRVLW + +P + ++ S+ S I+ TS
Sbjct: 664 KYNLPSWCDRVLW--KSYPL------VHVVCQSYGSTSDIM-----------------TS 698
Query: 897 DHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDE 956
DH PV A + + + + QG + + + + F+ +
Sbjct: 699 DHSPVFATFEAGVTSQFVSKNG---PGTVDSQGQIEFLRCYATLKTKSQTKFYLE-FHSS 754
Query: 957 LLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNL 1016
L+ F E E ++ V F E L + + + LL++ I I++KS D ++
Sbjct: 755 CLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESY 814
Query: 1017 EE---EMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHL--QP 1071
E + LE LP T T G E+ F E + + E L + +
Sbjct: 815 GEGCIALRLEATETQLPIYTPLTHHG---ELTGHFQGEIKLQTSQGKTREKLYDFVKTER 871
Query: 1072 SSSSGLGTSPS-----------SSPRTSPCQSPTISE------------GPVPSLPIRPS 1108
SSG T S + R PC +I+E GP L ++ +
Sbjct: 872 DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 931
Query: 1109 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPP-PPRPVAPPT--RPAPP--Q 1163
+P + P S P D+ P P + P P P +PP P+ P T R PP Q
Sbjct: 932 LSPDQQPTAWSYDQPPKDS-PLGPCRGESP--PTPPGQPPISPKKFLPSTANRGLPPRTQ 988
Query: 1164 RPPPPSGARSPAPTRKE---------------FGGIGAPPSPGVARREMEAPKSPGTTRK 1208
P ++ T + +G + + P P R++ E+PK P RK
Sbjct: 989 ESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKP-APRKDQESPKMP---RK 1044
Query: 1209 DNIGRSQPSPQAGLAGP---------GPAGYSTARPTIPPRAGVISAPQSHARASAGRLT 1259
+ P P+ G+ P G + PR + S +AG
Sbjct: 1045 E----PPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDK 1100
Query: 1260 PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAP 1309
+ + KT +S+ P+KP + Q + P P R P +PV +P
Sbjct: 1101 SQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPR---PPLPVKSP 1147
Score = 42.4 bits (98), Expect = 0.003
Identities = 52/219 (23%), Positives = 76/219 (34%), Gaps = 36/219 (16%)
Query: 1070 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS-----LPIRPSRAPSRTPGPPSAQSSP 1124
QP S LG SP T P Q P + +PS LP R + G + + P
Sbjct: 945 QPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLP 1004
Query: 1125 IDAQPAT------------------PLPQKDPAQPLEPKRPPPPRP---VAPP----TRP 1159
+ P T P P+KD P P++ PPP P + P T+
Sbjct: 1005 QEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKA 1064
Query: 1160 APPQRPPPPSGARSPAPTRKEFG-GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSP 1218
R P G + PAP + F A + PK+P +++ + P
Sbjct: 1065 QEADRGEGP-GKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKP 1123
Query: 1219 QAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR 1257
T RP +P ++ + H + S GR
Sbjct: 1124 SRSEINQQTPPTPTPRPPLPVKSPAV----LHLQHSKGR 1158
Score = 39.7 bits (91), Expect = 0.020
Identities = 51/195 (26%), Positives = 73/195 (37%), Gaps = 28/195 (14%)
Query: 1164 RPPPPSGARSPAPTRKEFGGIG--APPSPGVARREMEAPKSPGTTRKDNIGRSQP-SPQA 1220
R PP SG+ + G+G PP P ++ + + P D + P P
Sbjct: 897 RAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCR 956
Query: 1221 GLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPL 1280
G + P P G +P I P+ + P + R R T ES+ + G T E L
Sbjct: 957 GESPPTPPG----QPPISPKKFL---PSTANRGLPPR-TQESRPSDLGKNAGDTLPQEDL 1008
Query: 1281 ---KPQAAFPPQ----SSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSH 1333
KP+ P SS P PA R + +S P E PP P P S
Sbjct: 1009 PLTKPEMFENPLYGSLSSFPKPAPRKDQ----------ESPKMPRKEPPPCPEPGILSPS 1058
Query: 1334 SLPSEASSQPQQEQP 1348
+ ++A + E P
Sbjct: 1059 IVLTKAQEADRGEGP 1073
>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
sapiens]
Length = 1189
Score = 177 bits (450), Expect = 5e-44
Identities = 205/830 (24%), Positives = 331/830 (39%), Gaps = 141/830 (16%)
Query: 554 KVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEF 613
++L+ M + +P I + +GTWN+ + I T W L K G
Sbjct: 386 QLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKI-------TSWFLS--KGQGKTRD 436
Query: 614 QDKRSKPTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNK--YVLLASEQ 671
P DI+ IG +E ++K W L+ ++ + +A
Sbjct: 437 DSADYIPHDIYVIGTQE------------DPLSEKEWLEILKHSLQEITSVTFKTVAIHT 484
Query: 672 LVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAA 731
L + + V +P+H I + D VKTG+ GNKGAV + +F+ TSL FV SH +
Sbjct: 485 LWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTS 544
Query: 732 GQSQVKERNEDFIEIARKLSF---PMGRMLFSH--DYVFWCGDFNYRIDLPN---EEVKE 783
G + RN++++ I R L+ + +H ++FW GD NYR+DLP E + +
Sbjct: 545 GSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQ 604
Query: 784 LIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYD-LFSDDY------DTSE 836
I+QQ + L++ DQL+ ++ +VF F E ++TFAPTY+++ L D Y T
Sbjct: 605 KIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGM 664
Query: 837 KCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTS 896
K P+W DRVLW + +P + ++ S+ S I+ TS
Sbjct: 665 KYNLPSWCDRVLW--KSYPL------VHVVCQSYGSTSDIM-----------------TS 699
Query: 897 DHRPVVALIDIDIFEVEAEERQNIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDE 956
DH PV A + + + + QG + + + + F+ +
Sbjct: 700 DHSPVFATFEAGVTSQFVSKNG---PGTVDSQGQIEFLRCYATLKTKSQTKFYLE-FHSS 755
Query: 957 LLQQFASFGEVILIRFVEDKMWVTFLEGSSALNVLSLNGKELLNRTITIALKSPDWIKNL 1016
L+ F E E ++ V F E L + + + LL++ I I++KS D ++
Sbjct: 756 CLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESY 815
Query: 1017 EE---EMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHL--QP 1071
E + LE LP T T G E+ F E + + E L + +
Sbjct: 816 GEGCIALRLEATETQLPIYTPLTHHG---ELTGHFQGEIKLQTSQGKTREKLYDFVKTER 872
Query: 1072 SSSSGLGTSPS-----------SSPRTSPCQSPTISE------------GPVPSLPIRPS 1108
SSG T S + R PC +I+E GP L ++ +
Sbjct: 873 DESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQT 932
Query: 1109 RAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPP-PPRPVAPPT--RPAPP--Q 1163
+P + P S P D+ P P + P P P +PP P+ P T R PP Q
Sbjct: 933 LSPDQQPTAWSYDQPPKDS-PLGPCRGESP--PTPPGQPPISPKKFLPSTANRGLPPRTQ 989
Query: 1164 RPPPPSGARSPAPTRKE---------------FGGIGAPPSPGVARREMEAPKSPGTTRK 1208
P ++ T + +G + + P P R++ E+PK P RK
Sbjct: 990 ESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKP-APRKDQESPKMP---RK 1045
Query: 1209 DNIGRSQPSPQAGLAGP---------GPAGYSTARPTIPPRAGVISAPQSHARASAGRLT 1259
+ P P+ G+ P G + PR + S +AG
Sbjct: 1046 E----PPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDK 1101
Query: 1260 PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAP 1309
+ + KT +S+ P+KP + Q + P P R P +PV +P
Sbjct: 1102 SQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPR---PPLPVKSP 1148
Score = 42.4 bits (98), Expect = 0.003
Identities = 52/219 (23%), Positives = 76/219 (34%), Gaps = 36/219 (16%)
Query: 1070 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS-----LPIRPSRAPSRTPGPPSAQSSP 1124
QP S LG SP T P Q P + +PS LP R + G + + P
Sbjct: 946 QPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLP 1005
Query: 1125 IDAQPAT------------------PLPQKDPAQPLEPKRPPPPRP---VAPP----TRP 1159
+ P T P P+KD P P++ PPP P + P T+
Sbjct: 1006 QEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKA 1065
Query: 1160 APPQRPPPPSGARSPAPTRKEFG-GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSP 1218
R P G + PAP + F A + PK+P +++ + P
Sbjct: 1066 QEADRGEGP-GKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKP 1124
Query: 1219 QAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR 1257
T RP +P ++ + H + S GR
Sbjct: 1125 SRSEINQQTPPTPTPRPPLPVKSPAV----LHLQHSKGR 1159
Score = 39.7 bits (91), Expect = 0.020
Identities = 51/195 (26%), Positives = 73/195 (37%), Gaps = 28/195 (14%)
Query: 1164 RPPPPSGARSPAPTRKEFGGIG--APPSPGVARREMEAPKSPGTTRKDNIGRSQP-SPQA 1220
R PP SG+ + G+G PP P ++ + + P D + P P
Sbjct: 898 RAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCR 957
Query: 1221 GLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPL 1280
G + P P G +P I P+ + P + R R T ES+ + G T E L
Sbjct: 958 GESPPTPPG----QPPISPKKFL---PSTANRGLPPR-TQESRPSDLGKNAGDTLPQEDL 1009
Query: 1281 ---KPQAAFPPQ----SSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSH 1333
KP+ P SS P PA R + +S P E PP P P S
Sbjct: 1010 PLTKPEMFENPLYGSLSSFPKPAPRKDQ----------ESPKMPRKEPPPCPEPGILSPS 1059
Query: 1334 SLPSEASSQPQQEQP 1348
+ ++A + E P
Sbjct: 1060 IVLTKAQEADRGEGP 1074
>gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A
[Homo sapiens]
Length = 638
Score = 162 bits (409), Expect = 3e-39
Identities = 175/646 (27%), Positives = 269/646 (41%), Gaps = 96/646 (14%)
Query: 569 PKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGF 628
P + R+ V TWNV A +T L L G + S D+ AIG
Sbjct: 52 PSEPRITVVTWNVG-------TAMPPDDVTSLL----HLGGGDD-----SDGADMIAIGL 95
Query: 629 EEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPF 688
+E+ + + A T+Q W+ + N +VL++S ++ GV L +F + H PF
Sbjct: 96 QEVNSMLNKRLKDALFTDQ--WSELFMDALGPFN-FVLVSSVRMQGVILLLFAKYYHLPF 152
Query: 689 IRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFIEIAR 748
+RDV D +TG+GG GNKG V++R+ LCF+ H A + ++R ++F I
Sbjct: 153 LRDVQTDCTRTGLGGYWGNKGGVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILS 212
Query: 749 KLSF--PMGRMLFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGDQLINQKNA 805
F P + + HD VFW GD N+RI+ + VK I L DQL KN
Sbjct: 213 LQQFQGPGAQGILDHDLVFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNT 272
Query: 806 GQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRR-----KWPFDRSA 860
+ +GF EG + FAPT+K+D+ ++ YDTS K R PAWTDR+LW+ + P R +
Sbjct: 273 WPILKGFQEGPLNFAPTFKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKS 332
Query: 861 EDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVA--LIDIDIFEVEAEERQ 918
L + S++ E SDH+PV A L+ + R
Sbjct: 333 HRLQVTQHSYR-----------------SHMEYTVSDHKPVAAQFLLQFAFRDDMPLVRL 375
Query: 919 NIYKEVIAVQGPPDGTVLVSIKSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMW 978
+ E + P V +++ +++ L + + + + ED
Sbjct: 376 EVADEWVR---PEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYVAYVWAKH-EDVDG 431
Query: 979 VTFLEGSSALNVLSLNGKELL-----NRTITIALKSPDWIKNLEEEMSLEKISIALPSST 1033
T+ S ++ +G +L N +I I + P I+LPSS
Sbjct: 432 NTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEP--------------FQISLPSSE 477
Query: 1034 SSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSP 1093
L + ++ EG+ DD + E+ L P S S SP S R +SP
Sbjct: 478 ----LASSSTDSSGTSSEGE-DDSTLEL-------LAPKSRS---PSPGKSKR-HRSRSP 521
Query: 1094 TISEGPVPSLPIRPS----RAPSRTPGPPSAQSSPIDAQPAT-----PLPQKDPAQPLEP 1144
++ P L +RPS R SR+P P S + S + ++ ++ P+ P
Sbjct: 522 GLAR--FPGLALRPSSRERRGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGP 579
Query: 1145 KRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSP 1190
PP P + PA P G S P R+ PSP
Sbjct: 580 WAFPPAVPRSLGLLPALRLETVDPGGGGSWGPDREALAPNSLSPSP 625
>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sapiens]
Length = 1258
Score = 154 bits (388), Expect = 7e-37
Identities = 208/832 (25%), Positives = 331/832 (39%), Gaps = 176/832 (21%)
Query: 549 QSASSKVLKSMCENFYKYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLA 608
+ A ++L+ M K +P I V +GTWN+ +++ T W
Sbjct: 401 REAFCQLLQLMKNKHSKQDEPDMISVFIGTWNMGSVPPPKNV-------TSWFTSK---- 449
Query: 609 GIQEFQDKRSK--PTDIFAIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISR--DNKY 664
G+ + D+ + P DI+ G +E ++ + W L+ + D Y
Sbjct: 450 GLGKTLDEVTVTIPHDIYVFGTQE------------NSVGDREWLDLLRGGLKELTDLDY 497
Query: 665 VLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCF 724
+A + L + + V ++P+H I V+ +VKTG+ GNKGAV + +F+ TS F
Sbjct: 498 RPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIANTLGNKGAVGVSFMFNGTSFGF 557
Query: 725 VCSHFAAGQSQVKERNEDFIEIARKLSFPMGRMLFSHD------YVFWCGDFNYRIDLPN 778
V H +G + RN+++++I R LS R L + D ++FW GD NYR+D+
Sbjct: 558 VNCHLTSGNEKTARRNQNYLDILRLLSLG-DRQLNAFDISLRFTHLFWFGDLNYRLDMDI 616
Query: 779 EEVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDD------- 831
+E+ I ++ ++ L+ DQL ++ +VF F E +++F PTY+Y+ S D
Sbjct: 617 QEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSEEEISFPPTYRYERGSRDTYAWHKQ 676
Query: 832 YDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASF--------QDESKILYTWTPG 883
T + P+W DR+LW +S + ++ S+ D S + T+ G
Sbjct: 677 KPTGVRTNVPSWCDRILW--------KSYPETHIICNSYGCTDDIVTSDHSPVFGTFEVG 728
Query: 884 TLLHY--GRAELKTSDHRPVVALIDIDIFE--VEAEERQNIYKEVIAVQGPPDGTVLVSI 939
+ + KTSD A I+ + E V+ R + E + T L
Sbjct: 729 VTSQFISKKGLSKTSDQ----AYIEFESIEAIVKTASRTKFFIEFYS-------TCLEEY 777
Query: 940 KSSLPENNFFDDALIDELLQQFASFGEVILIRFVEDKMWVTFLEGSS-ALNVLSLNGKEL 998
K S EN+ I+ L Q++S L + D + +L+ L V S++G E
Sbjct: 778 KKSF-ENDAQSSDNINFLKVQWSSRQLPTLKPILAD---IEYLQDQHLLLTVKSMDGYES 833
Query: 999 LNRTITIALKSP---------DWIKNLEEEMS--LEKISIALPSSTSSTLLGEDAEVAAD 1047
+ +ALKS ++ + EE + + +P+ T
Sbjct: 834 YGECV-VALKSMIGSTAQQFLTFLSHRGEETGNIRGSMKVRVPTERLGT----------- 881
Query: 1048 FDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG--PVPSLPI 1105
E + S + +E + PS S G S PR S + P +E P+ L
Sbjct: 882 --RERLYEWISIDKDEAGAKSKAPSVSRG-----SQEPR-SGSRKPAFTEASCPLSRLFE 933
Query: 1106 RPSRAP--SRTPGPPSAQSSPIDAQPATPLPQKDPAQP-LEPKRPPPPRPVAPPTRPAPP 1162
P + P R P PP A P+++P P L+P+ P P VA
Sbjct: 934 EPEKPPPTGRPPAPPRA------------APREEPLTPRLKPEGAPEPEGVA-------- 973
Query: 1163 QRPPPPSGARSPAPTRKEFGGIG---APPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQ 1219
PPP + +PA E G+ PP P R AP T K+ + + P+PQ
Sbjct: 974 -APPPKNSFNNPAYYVLE--GVPHQLLPPEPPSPAR---APVPSAT--KNKVAITVPAPQ 1025
Query: 1220 AGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEP 1279
G H R G S ++ T F P P
Sbjct: 1026 LG-------------------------HHRHPRVGEG---SSSDEESGGTLPPPDFPPPP 1057
Query: 1280 LKPQAAFPPQS--SLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRS 1329
L A F P S LP P R + P P++ P+P L PP P P S
Sbjct: 1058 LPDSAIFLPPSLDPLPGPVVRGRGGAEARGPPPPKAHPRPPL--PPGPSPAS 1107
>gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]
Length = 644
Score = 135 bits (341), Expect = 2e-31
Identities = 104/360 (28%), Positives = 159/360 (44%), Gaps = 71/360 (19%)
Query: 565 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 624
+Y + + + V TWN+ G K+ +L ++LL A + D++
Sbjct: 292 RYFPDRNVALFVATWNMQGQKELPP------SLDEFLLPA-----------EADYAQDLY 334
Query: 625 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 684
IG +E ++++ W LQ+T+ YVLL+S + + +FIR
Sbjct: 335 VIGVQE------------GCSDRREWETRLQETLGPH--YVLLSSAAHGVLYMSLFIRRD 380
Query: 685 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 744
F +V TV T + KGA+ I F TS F+ SHF +G +V ER D+
Sbjct: 381 LIWFCSEVECSTVTTRIVSQIKTKGALGISFTFFGTSFLFITSHFTSGDGKVAERLLDYT 440
Query: 745 EIARKLSFPMG------------RMLFSHDYVFWCGDFNYRIDLPNEEVKELIRQQ---N 789
+ L P + D VFW GDFN+R+ V L+ Q +
Sbjct: 441 RTVQALVLPRNVPDTNPYRSSAADVTTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLVVD 500
Query: 790 WDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLW 849
+L+ DQLI + G +F+GF E + F P+YK+D+ D YD++ K RTP++TDRVL+
Sbjct: 501 VPALLQHDQLIREMRKGSIFKGFQEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLY 560
Query: 850 RRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDI 909
R R D + Y+ PG +KTSDHRPV L + +
Sbjct: 561 RSR----------------HKGDICPVSYSSCPG---------IKTSDHRPVYGLFRVKV 595
Score = 39.3 bits (90), Expect = 0.026
Identities = 48/200 (24%), Positives = 71/200 (35%), Gaps = 37/200 (18%)
Query: 1128 QPATPLPQKDPAQPLE---PKRPPPPRPVAPPTRPAPP------QRPPPPSGARSPA--- 1175
+P+ P PQ + L+ P PP R +PP P P PSG PA
Sbjct: 9 RPSEPAPQPPEGRTLQGQLPGAPPAQRAGSPPDAPGSESPALACSTPATPSGEDPPARAA 68
Query: 1176 ------PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLA---GPG 1226
P R + G RR +++D R+ SP G GPG
Sbjct: 69 PIAPRPPARPRLERALSLDDKGWRRRRFRG------SQEDLEARNGTSPSRGSVQSEGPG 122
Query: 1227 -------PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEP 1279
P ST+ IP GV+S+ + + L+ + S + + +
Sbjct: 123 APAHSCSPPCLSTSLQEIPKSRGVLSSERGSPSSGGNPLSGVASSSPNLPHRDAAVAGSS 182
Query: 1280 LKPQAAFPPQSSLPPPAQRL 1299
+ + PP+ PPPA L
Sbjct: 183 PRLPSLLPPR---PPPALSL 199
>gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo
sapiens]
Length = 448
Score = 133 bits (335), Expect = 1e-30
Identities = 98/301 (32%), Positives = 153/301 (50%), Gaps = 23/301 (7%)
Query: 615 DKRSKPTDIFAIGFEEMVELNAG--NIVSASTTNQKLWAVELQKTISRDNKYVLLASEQL 672
+ R+ DI+ IG +E LN+G +++S + N W+ L +S ++ ++ ++
Sbjct: 39 NNRNLNLDIYVIGLQE---LNSGIISLLSDAAFNDS-WSSFLMDVLS-PLSFIKVSHVRM 93
Query: 673 VGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAG 732
G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + + + H
Sbjct: 94 QGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPH 153
Query: 733 QSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNEEVKELIRQQ 788
S +R E F I + GR + HD + W GD N+RI D V+E I+ +
Sbjct: 154 ISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNR 212
Query: 789 NWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVL 848
+ L DQL K + R F EG++ F PTYK+D S+DYDTSEK R PAWTDR+L
Sbjct: 213 CYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRIL 272
Query: 849 WRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDID 908
WR ++ P + D + AS S Y+ + + YG SDH+PV D++
Sbjct: 273 WRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHKPVSGTFDLE 321
Query: 909 I 909
+
Sbjct: 322 L 322
>gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 125 bits (314), Expect = 3e-28
Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%)
Query: 664 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 723
++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + +
Sbjct: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68
Query: 724 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 779
+ H S +R E F I + GR + HD + W GD N+RI D
Sbjct: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127
Query: 780 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 839
V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R
Sbjct: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187
Query: 840 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 899
PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+
Sbjct: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236
Query: 900 PVVALIDIDI 909
PV D+++
Sbjct: 237 PVSGTFDLEL 246
>gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 125 bits (314), Expect = 3e-28
Identities = 84/250 (33%), Positives = 128/250 (51%), Gaps = 16/250 (6%)
Query: 664 YVLLASEQLVGVCLFVFIRPQHAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLC 723
++ ++ ++ G+ L VF + QH P+I+ ++ + TG+ G GNKG V I + + +
Sbjct: 9 FIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVS 68
Query: 724 FVCSHFAAGQSQVKERNEDFIEIARKLSFPMGR---MLFSHDYVFWCGDFNYRI-DLPNE 779
+ H S +R E F I + GR + HD + W GD N+RI D
Sbjct: 69 IINCHLPPHISNNYQRLEHFDRILEMQNCE-GRDIPNILDHDLIIWFGDMNFRIEDFGLH 127
Query: 780 EVKELIRQQNWDSLIAGDQLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCR 839
V+E I+ + + L DQL K + R F EG++ F PTYK+D S+DYDTSEK R
Sbjct: 128 FVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKR 187
Query: 840 TPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHR 899
PAWTDR+LWR ++ P + D + AS S Y+ + + YG SDH+
Sbjct: 188 KPAWTDRILWRLKRQPC--AGPDTPIPPASHFSLSLRGYS----SHMTYG-----ISDHK 236
Query: 900 PVVALIDIDI 909
PV D+++
Sbjct: 237 PVSGTFDLEL 246
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 92.0 bits (227), Expect = 3e-18
Identities = 89/308 (28%), Positives = 114/308 (37%), Gaps = 50/308 (16%)
Query: 1081 PSSSPRTSPCQSPTISEGPVPSLPIRP---------SRAPSRTPG-----PPSAQSSPID 1126
P P+ P Q +GP P P +P SR+P PG PP + P
Sbjct: 74 PPGKPQGPPPQGGNKPQGPPP--PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131
Query: 1127 AQPATPLPQKDPAQP-LEPKRPPPP-RPVAPPTR-----------PAPPQRPPPPSGARS 1173
P PQ P Q +P+ PPPP +P PP + P PQ PPP G +
Sbjct: 132 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP 191
Query: 1174 PAPTRKEFGGIGAPPSPGVARREMEAPKSPG-----TTRKDNIGRSQPSPQAGLAGPGPA 1228
P G PP G + + P PG + DN +S SP GP P
Sbjct: 192 QGPPPPPGKPQGPPPQGG---NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ 248
Query: 1229 GYS--------TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPL 1280
G + +P PP G + PQ + P S +S+ P+
Sbjct: 249 GGNQPQGPPPPPGKPQGPPPQGG-NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307
Query: 1281 KPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE--TPPQPPPRSRSSHSLPSE 1338
PQ PQ PPP + P P PQ P P PPQ +SRS+ S P +
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPP--PQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGK 365
Query: 1339 ASSQPQQE 1346
PQQE
Sbjct: 366 PQGPPQQE 373
Score = 85.5 bits (210), Expect = 3e-16
Identities = 89/314 (28%), Positives = 119/314 (37%), Gaps = 49/314 (15%)
Query: 1077 LGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQK 1136
L ++ + + S +SP++ G P + P P PP P PQ
Sbjct: 13 LSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP--PPQGGNQPQG 70
Query: 1137 DPAQPLEPKRPPPP---RPVAPPTRPAPPQRP--PPPSG--ARSP-APTRKEFG------ 1182
P P +P+ PPP +P PP PP +P PPP G +RSP +P K G
Sbjct: 71 PPPPPGKPQGPPPQGGNKPQGPP----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 126
Query: 1183 --GIGAPPSPGVAR-------REMEAPKSPG-----TTRKDNIGRSQPSPQAGLAGPGPA 1228
G PP PG + + + P PG + DN RS SP GP P
Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ 186
Query: 1229 GYS--------TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPL 1280
G + +P PP G + PQ + P S++++ P+
Sbjct: 187 GGNQPQGPPPPPGKPQGPPPQGG-NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245
Query: 1281 KPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE--TPPQPPPRSRSSHSLPSE 1338
PQ PQ PPP + P P PQ P P PPQ +SRSS S P +
Sbjct: 246 PPQGGNQPQGPPPPPGKPQGPP--PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK 303
Query: 1339 ASSQPQQ--EQPSG 1350
P Q QP G
Sbjct: 304 PQGPPPQGGNQPQG 317
Score = 78.2 bits (191), Expect = 5e-14
Identities = 77/275 (28%), Positives = 102/275 (37%), Gaps = 39/275 (14%)
Query: 1070 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
Q + S SP P+ P Q +GP P P +P P + P Q P +P
Sbjct: 165 QGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGNKP--QGPPPPGKP 221
Query: 1130 ATPLPQKDP------AQPLEPKRPPPP---RPVAPPTRPAPPQRPPPPSGARS---PAPT 1177
P PQ D + P +P+ PPP +P PP P PQ PPP G + P P
Sbjct: 222 QGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281
Query: 1178 RKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTI 1237
+ + G PP G R +P PG + P PQ G GP
Sbjct: 282 KPQ----GPPPQGGSKSRSSRSP--PGKPQG-------PPPQGGNQPQGPPPPPGKPQGP 328
Query: 1238 PPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ 1297
PP+ G + PQ + P S +++ P+ Q PQ PP
Sbjct: 329 PPQGG--NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGG 386
Query: 1298 RLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSS 1332
Q+P P A QP + PP+PP R S
Sbjct: 387 NPQQPQAPPAG-------QP--QGPPRPPQGGRPS 412
Score = 55.8 bits (133), Expect = 3e-07
Identities = 40/136 (29%), Positives = 48/136 (35%), Gaps = 12/136 (8%)
Query: 1070 QPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQP 1129
Q S S SP P+ P Q +GP P P + GPP + P
Sbjct: 289 QGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPP--------PGKPQGPPPQGGNKPQGPP 340
Query: 1130 ATPLPQKDPAQ---PLEPKRPPPPRPVAPPTRPAP-PQRPPPPSGARSPAPTRKEFGGIG 1185
PQ P Q R PP +P PP + PQ PPPP+G P G
Sbjct: 341 PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ 400
Query: 1186 APPSPGVARREMEAPK 1201
PP P R P+
Sbjct: 401 GPPRPPQGGRPSRPPQ 416
Score = 55.1 bits (131), Expect = 5e-07
Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 23/181 (12%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS--LPIRPSRAPSRTP-GPPSAQS 1122
PQ P G P + P +GP P R SR+P P GPP
Sbjct: 253 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG 312
Query: 1123 SPIDAQPATPLPQKDPAQPLEPKRPPPP---RPVAPPTRPAPPQRPPPPSGARSPAPTRK 1179
+ PQ P P +P+ PPP +P PP P PQ PPP G++S R
Sbjct: 313 NQ---------PQGPPPPPGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGGSKS----RS 358
Query: 1180 EFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPP 1239
G P P ++E P+ P N + Q P GP P RP+ PP
Sbjct: 359 ARSPPGKPQGP--PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP-PRPPQGGRPSRPP 415
Query: 1240 R 1240
+
Sbjct: 416 Q 416
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 92.0 bits (227), Expect = 3e-18
Identities = 102/342 (29%), Positives = 134/342 (39%), Gaps = 65/342 (19%)
Query: 1049 DMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS---LPI 1105
D E D D SA+ + L Q + +G+ +PSS+P +P Q PT GP PS +P
Sbjct: 166 DNESDSDS-SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP-QLPT--PGPTPSATAVPP 221
Query: 1106 RPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP------ 1159
+ S S+ P P A ++P+ P P +P P PP P P PP +P
Sbjct: 222 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAG 280
Query: 1160 ---APPQRPPPPSGARSPAPTRKEFGGI----------GAPP-----------SPGVA-- 1193
AP PP G P P + G + G PP SP A
Sbjct: 281 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340
Query: 1194 RREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARA 1253
++ P S + R QP P A LA P + PT P + APQ+H
Sbjct: 341 HTSLQLPASQSALQSQQPPREQPLPPAPLAMP----HIKPPPTTP--IPQLPAPQAHKH- 393
Query: 1254 SAGRLTPESQSKTSETSKGSTFLPEP-LKPQAAFP---PQSSLPPPAQRLQEPLVPVAAP 1309
P S S S + P P LKP ++ P S+ PPP Q L+P + P
Sbjct: 394 ------PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ-----LMPQSQP 442
Query: 1310 MPQSGPQPNLETPPQ---PPPRSRSSHSLPSEASSQPQQEQP 1348
+P S QP T Q PPP S L A P + P
Sbjct: 443 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHP 484
Score = 43.1 bits (100), Expect = 0.002
Identities = 64/288 (22%), Positives = 93/288 (32%), Gaps = 32/288 (11%)
Query: 1070 QPSSSSGLGTSP-----SSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
QP+S G TSP SS R SP + T S + ++ P +
Sbjct: 37 QPASPDGR-TSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 95
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP--APPQRPPPPSGARSPAPTRKEFG 1182
+ A+ + D + K RP +P + R G+ P K+
Sbjct: 96 QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDP----KDID 151
Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1242
SP + + S + ++ + P+ QA P G + A + PP G
Sbjct: 152 QDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQA------PTGVTPAPSSAPP--G 203
Query: 1243 VISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEP 1302
P SA + P+ S+ +P P A P PA Q P
Sbjct: 204 TPQLPTPGPTPSATAVPPQGSPTASQAPN------QPQAPTAPVPHTHIQQAPALHPQRP 257
Query: 1303 LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1350
P P P P+ P QP S S PS A + P G
Sbjct: 258 ------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 299
Score = 41.6 bits (96), Expect = 0.005
Identities = 48/149 (32%), Positives = 59/149 (39%), Gaps = 18/149 (12%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRP-SRAPSRTPGPPSAQSSP 1124
P L+P SS PS+ P P Q S+ P+PS P +P S+ PP A P
Sbjct: 412 PPALKPLSSLSTHHPPSAHP--PPLQLMPQSQ-PLPSSPAQPPGLTQSQNLPPPPASHPP 468
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPV---APPTRPAPP--QRPPPPSGARSPAPTRK 1179
P P P P PPP P + T PA P PP SGA A +
Sbjct: 469 TGLHQVAPQPPF-AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGA---AASGG 524
Query: 1180 EFGGIGAPPSPGVARRE-----MEAPKSP 1203
G + P P V +E E P+SP
Sbjct: 525 SIAGGSSCPLPTVQIKEEALDDAEEPESP 553
Score = 39.3 bits (90), Expect = 0.026
Identities = 47/155 (30%), Positives = 61/155 (39%), Gaps = 36/155 (23%)
Query: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP-----SLPIRPSRAPSR---TPGPPS 1119
H++P ++ + P+ P P +S GP P +LP P+ P T PPS
Sbjct: 373 HIKPPPTTPIPQLPAPQAHKHP---PHLS-GPSPFSMNANLPPPPALKPLSSLSTHHPPS 428
Query: 1120 AQSSPIDAQPAT-PLPQKDPAQP---LEPKRPPPPRPVAPPT-----RPAPP--QRP--- 1165
A P+ P + PLP PAQP + + PPP PPT P PP Q P
Sbjct: 429 AHPPPLQLMPQSQPLPSS-PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP 487
Query: 1166 -------PPPSGARSPAPTRKEFGGIGAPPSPGVA 1193
PP + S P G PP G A
Sbjct: 488 GGPPPITPPTCPSTSTPPAGP--GTSAQPPCSGAA 520
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 92.0 bits (227), Expect = 3e-18
Identities = 102/342 (29%), Positives = 134/342 (39%), Gaps = 65/342 (19%)
Query: 1049 DMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS---LPI 1105
D E D D SA+ + L Q + +G+ +PSS+P +P Q PT GP PS +P
Sbjct: 720 DNESDSDS-SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP-QLPT--PGPTPSATAVPP 775
Query: 1106 RPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP------ 1159
+ S S+ P P A ++P+ P P +P P PP P P PP +P
Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAG 834
Query: 1160 ---APPQRPPPPSGARSPAPTRKEFGGI----------GAPP-----------SPGVA-- 1193
AP PP G P P + G + G PP SP A
Sbjct: 835 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894
Query: 1194 RREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARA 1253
++ P S + R QP P A LA P + PT P + APQ+H
Sbjct: 895 HTSLQLPASQSALQSQQPPREQPLPPAPLAMP----HIKPPPTTP--IPQLPAPQAHKH- 947
Query: 1254 SAGRLTPESQSKTSETSKGSTFLPEP-LKPQAAFP---PQSSLPPPAQRLQEPLVPVAAP 1309
P S S S + P P LKP ++ P S+ PPP Q L+P + P
Sbjct: 948 ------PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ-----LMPQSQP 996
Query: 1310 MPQSGPQPNLETPPQ---PPPRSRSSHSLPSEASSQPQQEQP 1348
+P S QP T Q PPP S L A P + P
Sbjct: 997 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHP 1038
Score = 43.1 bits (100), Expect = 0.002
Identities = 64/288 (22%), Positives = 93/288 (32%), Gaps = 32/288 (11%)
Query: 1070 QPSSSSGLGTSP-----SSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
QP+S G TSP SS R SP + T S + ++ P +
Sbjct: 591 QPASPDGR-TSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 649
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP--APPQRPPPPSGARSPAPTRKEFG 1182
+ A+ + D + K RP +P + R G+ P K+
Sbjct: 650 QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDP----KDID 705
Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1242
SP + + S + ++ + P+ QA P G + A + PP G
Sbjct: 706 QDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQA------PTGVTPAPSSAPP--G 757
Query: 1243 VISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEP 1302
P SA + P+ S+ +P P A P PA Q P
Sbjct: 758 TPQLPTPGPTPSATAVPPQGSPTASQAPN------QPQAPTAPVPHTHIQQAPALHPQRP 811
Query: 1303 LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1350
P P P P+ P QP S S PS A + P G
Sbjct: 812 ------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 853
Score = 41.6 bits (96), Expect = 0.005
Identities = 48/149 (32%), Positives = 59/149 (39%), Gaps = 18/149 (12%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRP-SRAPSRTPGPPSAQSSP 1124
P L+P SS PS+ P P Q S+ P+PS P +P S+ PP A P
Sbjct: 966 PPALKPLSSLSTHHPPSAHP--PPLQLMPQSQ-PLPSSPAQPPGLTQSQNLPPPPASHPP 1022
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPV---APPTRPAPP--QRPPPPSGARSPAPTRK 1179
P P P P PPP P + T PA P PP SGA A +
Sbjct: 1023 TGLHQVAPQPPF-AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGA---AASGG 1078
Query: 1180 EFGGIGAPPSPGVARRE-----MEAPKSP 1203
G + P P V +E E P+SP
Sbjct: 1079 SIAGGSSCPLPTVQIKEEALDDAEEPESP 1107
Score = 39.3 bits (90), Expect = 0.026
Identities = 47/155 (30%), Positives = 61/155 (39%), Gaps = 36/155 (23%)
Query: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP-----SLPIRPSRAPSR---TPGPPS 1119
H++P ++ + P+ P P +S GP P +LP P+ P T PPS
Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHP---PHLS-GPSPFSMNANLPPPPALKPLSSLSTHHPPS 982
Query: 1120 AQSSPIDAQPAT-PLPQKDPAQP---LEPKRPPPPRPVAPPT-----RPAPP--QRP--- 1165
A P+ P + PLP PAQP + + PPP PPT P PP Q P
Sbjct: 983 AHPPPLQLMPQSQPLPSS-PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP 1041
Query: 1166 -------PPPSGARSPAPTRKEFGGIGAPPSPGVA 1193
PP + S P G PP G A
Sbjct: 1042 GGPPPITPPTCPSTSTPPAGP--GTSAQPPCSGAA 1074
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 92.0 bits (227), Expect = 3e-18
Identities = 102/342 (29%), Positives = 134/342 (39%), Gaps = 65/342 (19%)
Query: 1049 DMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPS---LPI 1105
D E D D SA+ + L Q + +G+ +PSS+P +P Q PT GP PS +P
Sbjct: 720 DNESDSDS-SAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP-QLPT--PGPTPSATAVPP 775
Query: 1106 RPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP------ 1159
+ S S+ P P A ++P+ P P +P P PP P P PP +P
Sbjct: 776 QGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAG 834
Query: 1160 ---APPQRPPPPSGARSPAPTRKEFGGI----------GAPP-----------SPGVA-- 1193
AP PP G P P + G + G PP SP A
Sbjct: 835 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894
Query: 1194 RREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARA 1253
++ P S + R QP P A LA P + PT P + APQ+H
Sbjct: 895 HTSLQLPASQSALQSQQPPREQPLPPAPLAMP----HIKPPPTTP--IPQLPAPQAHKH- 947
Query: 1254 SAGRLTPESQSKTSETSKGSTFLPEP-LKPQAAFP---PQSSLPPPAQRLQEPLVPVAAP 1309
P S S S + P P LKP ++ P S+ PPP Q L+P + P
Sbjct: 948 ------PPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ-----LMPQSQP 996
Query: 1310 MPQSGPQPNLETPPQ---PPPRSRSSHSLPSEASSQPQQEQP 1348
+P S QP T Q PPP S L A P + P
Sbjct: 997 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHP 1038
Score = 43.1 bits (100), Expect = 0.002
Identities = 64/288 (22%), Positives = 93/288 (32%), Gaps = 32/288 (11%)
Query: 1070 QPSSSSGLGTSP-----SSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
QP+S G TSP SS R SP + T S + ++ P +
Sbjct: 591 QPASPDGR-TSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKR 649
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP--APPQRPPPPSGARSPAPTRKEFG 1182
+ A+ + D + K RP +P + R G+ P K+
Sbjct: 650 QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDP----KDID 705
Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1242
SP + + S + ++ + P+ QA P G + A + PP G
Sbjct: 706 QDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQA------PTGVTPAPSSAPP--G 757
Query: 1243 VISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEP 1302
P SA + P+ S+ +P P A P PA Q P
Sbjct: 758 TPQLPTPGPTPSATAVPPQGSPTASQAPN------QPQAPTAPVPHTHIQQAPALHPQRP 811
Query: 1303 LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1350
P P P P+ P QP S S PS A + P G
Sbjct: 812 ------PSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 853
Score = 41.6 bits (96), Expect = 0.005
Identities = 48/149 (32%), Positives = 59/149 (39%), Gaps = 18/149 (12%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRP-SRAPSRTPGPPSAQSSP 1124
P L+P SS PS+ P P Q S+ P+PS P +P S+ PP A P
Sbjct: 966 PPALKPLSSLSTHHPPSAHP--PPLQLMPQSQ-PLPSSPAQPPGLTQSQNLPPPPASHPP 1022
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPV---APPTRPAPP--QRPPPPSGARSPAPTRK 1179
P P P P PPP P + T PA P PP SGA A +
Sbjct: 1023 TGLHQVAPQPPF-AQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGA---AASGG 1078
Query: 1180 EFGGIGAPPSPGVARRE-----MEAPKSP 1203
G + P P V +E E P+SP
Sbjct: 1079 SIAGGSSCPLPTVQIKEEALDDAEEPESP 1107
Score = 39.3 bits (90), Expect = 0.026
Identities = 47/155 (30%), Positives = 61/155 (39%), Gaps = 36/155 (23%)
Query: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP-----SLPIRPSRAPSR---TPGPPS 1119
H++P ++ + P+ P P +S GP P +LP P+ P T PPS
Sbjct: 927 HIKPPPTTPIPQLPAPQAHKHP---PHLS-GPSPFSMNANLPPPPALKPLSSLSTHHPPS 982
Query: 1120 AQSSPIDAQPAT-PLPQKDPAQP---LEPKRPPPPRPVAPPT-----RPAPP--QRP--- 1165
A P+ P + PLP PAQP + + PPP PPT P PP Q P
Sbjct: 983 AHPPPLQLMPQSQPLPSS-PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP 1041
Query: 1166 -------PPPSGARSPAPTRKEFGGIGAPPSPGVA 1193
PP + S P G PP G A
Sbjct: 1042 GGPPPITPPTCPSTSTPPAGP--GTSAQPPCSGAA 1074
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 91.7 bits (226), Expect = 4e-18
Identities = 82/295 (27%), Positives = 107/295 (36%), Gaps = 38/295 (12%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPI 1125
P PS GL T P T+P +P +G + + P P AP+ P + +
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP--PKGAPTTPAATPPSPKGGL 1163
Query: 1126 DAQPATPLPQKDPAQPLEPKRP-PPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGI 1184
P P A P PK P P PT PA P P G +P+P
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP-PSPKGGLATPSPKGAPTTPA 1222
Query: 1185 GAPPSP--GVARREME-APKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPR- 1240
PPSP G+A + AP +P T PSP+ G A P P G T PP
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAAT--------PPSPKGGPATPPPKGAPTPPAATPPSL 1274
Query: 1241 AGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQ 1300
G ++ P + +TP P P A PP+ + PPA
Sbjct: 1275 KGGLATPPHKGAPNPAVVTP----------------PSPKGGPATSPPKGAPTPPAATPP 1318
Query: 1301 EPLVPVAAPMPQSGPQPNLETPPQP------PPRSRSSHSLPSEASSQPQQEQPS 1349
P P P+ P P TPP P P + SS P+ SS+ P+
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373
Score = 85.9 bits (211), Expect = 2e-16
Identities = 79/286 (27%), Positives = 104/286 (36%), Gaps = 25/286 (8%)
Query: 1073 SSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATP 1132
S G T P+++P + T S P+ P +P P PS + +P P
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994
Query: 1133 LPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGV 1192
P+ PA P PK P P V PP+ P P P GA +P PPSP
Sbjct: 995 SPKGGPATP-SPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP--------AATPPSPKG 1045
Query: 1193 ARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPR-AGVISAPQSHA 1251
+ PK TT + PSP+ G A P G T PP G + P
Sbjct: 1046 SPAATPLPKGAPTTPAATL----PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101
Query: 1252 RASAGRLTPESQS--------KTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPL 1303
TP S K + T+ +T P P A PP+ + PA P
Sbjct: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAAT-PPSPKGGLATPPPKGAPTTPAATPPSPK 1160
Query: 1304 VPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPS 1349
+A P P+ P TPP P+ + P A + P PS
Sbjct: 1161 GGLATPPPKGAPTTPAATPPS--PKGGLATPSPKGAPTTPAATPPS 1204
Score = 85.1 bits (209), Expect = 4e-16
Identities = 83/300 (27%), Positives = 102/300 (34%), Gaps = 50/300 (16%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLP---------------IRPSRA 1110
P + P S G+ P +P S P EGP P R + A
Sbjct: 867 PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926
Query: 1111 PSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSG 1170
P P PS + +P P P+ PA P PK P P PP+ P P P
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATP-SPKWAPTPPAATPPSPKGGPATPSPKGA 985
Query: 1171 ARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAG-LAGPGPAG 1229
PA T G A PSP AP P T PSP+ A P P G
Sbjct: 986 PTPPAATPPSPKGGPATPSP------KGAPTPPAVT--------PPSPKGSPAATPFPKG 1031
Query: 1230 YSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQ 1289
ST PP A S S A + P + + T + KG P P P
Sbjct: 1032 AST-----PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG-----PATPSLKGAP- 1080
Query: 1290 SSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQP-----PPRSRSSHSLPSEASSQPQ 1344
PPA P A P P+ P P TPP P P + + + P+ P+
Sbjct: 1081 ---TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137
Score = 83.2 bits (204), Expect = 2e-15
Identities = 82/295 (27%), Positives = 114/295 (38%), Gaps = 31/295 (10%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQS-PTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
P + P S G T P+++P + + P+ EGP P P+ PS GP SP
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP-----PAATPSHKGGPAMTPPSP 1389
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRP--APPQR----PP---PPSGARSPA 1175
PA P P+ DP P P P P TR A P + PP P S ++PA
Sbjct: 1390 -KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448
Query: 1176 PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP 1235
+ + GG P S G P SP + SP+ A P P G P
Sbjct: 1449 TSAPK-GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG----AP 1503
Query: 1236 TIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKP-QAAFPPQSSLPP 1294
T+P A + S+P+ + R P + + T + K P L P +A PP ++P
Sbjct: 1504 TLP--AVIPSSPKEVPATPSSRRDPIAPTATLLSKK----TPATLAPKEALIPPAMTVPS 1557
Query: 1295 PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPS 1349
P + P +P P + +PP P + P E P PS
Sbjct: 1558 PK---KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609
Score = 81.3 bits (199), Expect = 6e-15
Identities = 87/322 (27%), Positives = 109/322 (33%), Gaps = 49/322 (15%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEG-----PVPSLPIRPSRAPSR------T 1114
P PS GL T P T+P +P +G P P P+ P T
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188
Query: 1115 PGPPSAQSSPIDAQP------ATPLPQKDPAQPL-------------EPKRPPPPRPVAP 1155
P P A ++P P ATP P+ P P PK P P
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248
Query: 1156 PTRPAPPQRPPPPSGARSPAPTRKEF-GGIGAPPSPGVARREMEAPKSPGTTRKDNIGRS 1214
P+ P PPP PA T GG+ PP G + P SP + +
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308
Query: 1215 QPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGST 1274
P+P A P P G P PP G + P + G TP + T+ +SKG
Sbjct: 1309 APTPPAA-TPPSPKG----SPGTPPPKGAPTPPAVTPPSPKG--TP-TLPATTPSSKGGP 1360
Query: 1275 FLP---EPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQP-----P 1326
P E P AA P S PA P A P P+ P P P
Sbjct: 1361 TTPSSKEGPTPPAATP--SHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418
Query: 1327 PRSRSSHSLPSEASSQPQQEQP 1348
P +R + PS+ P P
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTP 1440
Score = 79.0 bits (193), Expect = 3e-14
Identities = 82/295 (27%), Positives = 108/295 (36%), Gaps = 42/295 (14%)
Query: 1066 PQHLQPSSSSGLGTSPS-----SSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSA 1120
PQ +P + G + SSP SP ++ + E + + S A + +P PPS
Sbjct: 803 PQTKRPPTKKGSAGPDTPIGNLSSP-VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSP 861
Query: 1121 QSSPIDAQPATPLPQKDPAQPLEPKRPPPPR------PVAPPTRPAPPQRPPPPSGARSP 1174
+ +P + TPL K P PK P P P P PAP Q P + SP
Sbjct: 862 KGAPTPSA-VTPLSPKGVTLP--PKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP 918
Query: 1175 APTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTAR 1234
R G P SP AP P T PSP+ G A P P T
Sbjct: 919 KKARATPAPKGIPASPS----PKGAPTPPAAT--------PPSPKGGPATPSPKWAPTPP 966
Query: 1235 PTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPP 1294
PP +P+ + + P + T + KG P P A PP + P
Sbjct: 967 AATPP------SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP--KGAPTPPAVTPPS 1018
Query: 1295 PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPS 1349
P P A P P+ P TPP P S ++ LP A + P PS
Sbjct: 1019 PKGS------PAATPFPKGASTPPAATPPS-PKGSPAATPLPKGAPTTPAATLPS 1066
Score = 72.8 bits (177), Expect = 2e-12
Identities = 78/277 (28%), Positives = 107/277 (38%), Gaps = 50/277 (18%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPI 1125
P +P + + TS SSP+ +P + P+LP +P P PS++ PI
Sbjct: 1473 PSPKEPPAPKQVATS--SSPKKAPATPAPMG---APTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 1126 DAQPATPLPQKDPAQPLEPKR---------PPPPRPVAPPTRPAPPQRPPPPSGARSPAP 1176
A AT L +K PA L PK P P + A PT P P + PA
Sbjct: 1528 -APTATLLSKKTPAT-LAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
Query: 1177 TRKEFGGIGAP-----PSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYS 1231
T + G +P P + EAP P T PSP+ G A P P G
Sbjct: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT--------PPSPEKGPATPAPKGTP 1637
Query: 1232 TARPTIPPRAGVISAPQSHARASA--GRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQ 1289
T+ P P + + +P S A + G P++ SK KG T L E L A P+
Sbjct: 1638 TSPPVTP--SSLKDSPTSPASVTCKMGATVPQA-SKGLPAKKGPTALKEVLVAPA---PE 1691
Query: 1290 SSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPP 1326
S+ P+ + GPQ + PP
Sbjct: 1692 ST-------------PIITAPTRKGPQTKKSSATSPP 1715
Score = 60.5 bits (145), Expect = 1e-08
Identities = 79/346 (22%), Positives = 127/346 (36%), Gaps = 65/346 (18%)
Query: 1061 VEELLPQHLQPSSSSGLGT-SPSSSP------RTSPCQSPTISEGPVPSLPIRPSRAPSR 1113
+E P + P+++ G T + ++SP +P P + EG + +LP+ P+ A
Sbjct: 650 LESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP-VKEGTLTTLPLVPT-ASEN 707
Query: 1114 TPGPPSAQSS--PIDAQPATP-LPQKDPAQPLEPKRPPPPRP---------VAPPTRPAP 1161
P PS Q++ P+ P +P+ P+ L P PP P +P
Sbjct: 708 CPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSP 767
Query: 1162 PQRPPPPSGARSPAPTRKEFGGIGAPPSP---GVARREMEAPKSPGTTRKDN-IGR---- 1213
+ P SGA + A ++ + PSP V+ + P G+ D IG
Sbjct: 768 KECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827
Query: 1214 --------------------------SQPSPQAGLAGPGPAGYSTARP---TIPPRAGVI 1244
P+P + P P+ + P T+PP+
Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887
Query: 1245 SAPQSHARASAGRLTPESQ-----SKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL 1299
+ + G TP + S TS + K + P P A+ P+ + PPA
Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP 947
Query: 1300 QEPLVPVAAPMPQSGPQPNLETPPQPP--PRSRSSHSLPSEASSQP 1343
P A P P+ P P TPP P P + S P+ ++ P
Sbjct: 948 PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993
Score = 60.1 bits (144), Expect = 1e-08
Identities = 92/343 (26%), Positives = 124/343 (36%), Gaps = 91/343 (26%)
Query: 1071 PSSSSGLGTSPSS------------SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPP 1118
PSS + +PSS S +T +P E +P PS P +TP P
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP--KEALIPPAMTVPS--PKKTPAIP 1565
Query: 1119 SAQSSPI-------DAQPA-TPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQ--RPPPP 1168
+ + +P + PA TP K P E PP +P P PP P P
Sbjct: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Query: 1169 SGARSPAPTRKEFGGIGAPPSPGVARREM-EAPKSPGTTRKDNIGRSQPSPQAGLA---G 1224
G +PAP G P SP V + ++P SP + +G + P GL G
Sbjct: 1626 KGPATPAPK-------GTPTSPPVTPSSLKDSPTSPASVTC-KMGATVPQASKGLPAKKG 1677
Query: 1225 P--------GPAGYSTARPTIPPRAGV-----------ISAPQSHARASAGRLTPES--- 1262
P PA ST T P R G I S S G L+ +
Sbjct: 1678 PTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP 1737
Query: 1263 ----QSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVA----APMPQS- 1313
Q +S+T+KG A+ P+ L PP + PL A P P+S
Sbjct: 1738 LLPVQKDSSKTAKGK---------DASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788
Query: 1314 ----GPQPNLETP------PQPPPRSR---SSHSLPSEASSQP 1343
P P + P P PP+ + SS L E+ S+P
Sbjct: 1789 SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKP 1831
Score = 53.9 bits (128), Expect = 1e-06
Identities = 73/332 (21%), Positives = 110/332 (33%), Gaps = 66/332 (19%)
Query: 1084 SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP----GPPSAQSSPIDAQPATPLPQKDPA 1139
SP+ +P PT E P S P+ TP G PS + I +P P++ P
Sbjct: 1557 SPKKTPA-IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615
Query: 1140 QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGAR----SPAPTRKEFG--------GIGAP 1187
P P P P + P P PS + SPA + G G+ A
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675
Query: 1188 PSPGVARREMEAPKSPGT------TRKDNIGRSQ--------PSPQAGLAGPGPAGYSTA 1233
P + + AP T TRK + P P A GP
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAP 1735
Query: 1234 RPTIPPRA----------------GVISAPQSHAR-----ASAGRLTPESQSKT-SETSK 1271
P +P + G ++ P+S A A+ ++ P+ +S + S
Sbjct: 1736 APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS 1795
Query: 1272 GSTFLPEPLKPQAAFPPQSSLPPPAQRL-------------QEPLVPVAAPMPQSGPQPN 1318
LP P PP+ P + L ++ L+P+ P P SG P
Sbjct: 1796 PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF 1855
Query: 1319 LETPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1350
P + +P+ ++ QP + G
Sbjct: 1856 QSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKG 1887
Score = 53.1 bits (126), Expect = 2e-06
Identities = 62/235 (26%), Positives = 86/235 (36%), Gaps = 39/235 (16%)
Query: 1117 PPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAP 1176
P + Q P LP P P + PP PAP Q P + SP P
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPT-LPPPCSPAPQQCPLSAANQASPFP 68
Query: 1177 TRKEFGGIGAPPSPGVARREMEAP---KSPGTTRKDNIGRSQPSPQAGLAGP--GPAGYS 1231
+ PS +A +E P S GT P+ L GP PA +
Sbjct: 69 S----------PST-IASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALA 117
Query: 1232 TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
A P I P + P S A + L P S K+S AFPP
Sbjct: 118 LASPMIAPT--LKGTPSSSAPLALVALAPHSVQKSS-----------------AFPPNLL 158
Query: 1292 LPPPAQRLQE--PLVPVAAPMPQSGPQPNL-ETPPQPPPRSRSSHSLPSEASSQP 1343
PP+ + E ++ ++AP+ S P+ NL + P + P + + S P S+ P
Sbjct: 159 TSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP 213
Score = 42.4 bits (98), Expect = 0.003
Identities = 79/316 (25%), Positives = 117/316 (37%), Gaps = 53/316 (16%)
Query: 1077 LGTSPSSSPRTSPCQSPTISEGPV----PSLPIRPSRAPSRTPGPPSAQSSPIDAQPATP 1132
+ +P+++ + C SP +S GP+ P+ P AP P + ++ + + P
Sbjct: 449 IAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPP 508
Query: 1133 LPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGV 1192
LP P + K P V PT+ P G AP G+ P V
Sbjct: 509 LP-----DPEDLKNLPSSVLVKFPTQKDLQTVPASLEG----APFSPAQAGLTTKKDPTV 559
Query: 1193 ARREMEAPKSPGTTRKDNIGRSQP-SPQAGLA-----GPGPAGYSTARPTIP----PRAG 1242
APK+ + + + P SP+A LA P P G + T P A
Sbjct: 560 LPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSAS 619
Query: 1243 VISAPQSHARASAGRL------TPESQSKTSETSKGSTFLPEPLKPQAAFPPQS------ 1290
VI SAG L TP + E++ + P K + + +
Sbjct: 620 VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG 679
Query: 1291 --SLPPPAQRLQE------PLVPVA------APMPQS--GPQPNLETPPQPPPRSRSSHS 1334
SL P ++E PLVP A AP PQ+ P L P+ P+S S S
Sbjct: 680 TVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPE-IPKSVPSPS 738
Query: 1335 LPSEASSQPQQEQPSG 1350
LP A + P ++ G
Sbjct: 739 LP-PAGTPPGTKKVDG 753
Score = 37.7 bits (86), Expect = 0.075
Identities = 78/340 (22%), Positives = 109/340 (32%), Gaps = 72/340 (21%)
Query: 1050 MEGDVDDYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSR 1109
M G+ + E+ LPQ P + + + P +S P P+LP
Sbjct: 1 MPGEATETVPATEQELPQ---PQAETAV------LPMSSALSVTAALGQPGPTLP----- 46
Query: 1110 APSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLE-----------------PKRP----- 1147
P +P P S + P P + PLE P+ P
Sbjct: 47 -PPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPN 105
Query: 1148 ---PPPRP---------VAPPTRPAPPQRPPPPSGARSPAPTRKEFGG----IGAPPSPG 1191
PP P +AP + P P A +P +K + +PPS
Sbjct: 106 LIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVA 165
Query: 1192 VARREME-------APKSPGTTRKDNIGRSQPSPQAGLAGP---GPAGYSTARPTIPPRA 1241
VA AP P T P+P+ + P Y P ++
Sbjct: 166 VAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQS 225
Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
GV S PQ+ + +P+ + T S+ L P P + PP A L
Sbjct: 226 GVASLPQTTPTTTLAIASPQVKDTTI-----SSVLISPQNPGSLSLKGPVSPPAALSLST 280
Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASS 1341
+PV Q PN TPP P S SH P SS
Sbjct: 281 QSLPVVT-SSQKTAGPN--TPPD-FPISLGSHLAPLHQSS 316
Score = 37.4 bits (85), Expect = 0.098
Identities = 73/340 (21%), Positives = 110/340 (32%), Gaps = 50/340 (14%)
Query: 1018 EEMSLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSA--EVEELLPQHLQPSSSS 1075
++ L + A P + ST+ EV G E LP + P
Sbjct: 54 QQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPP--- 110
Query: 1076 GLGTSPSSSPRTSPCQSPTISEGPVPSLPIR-----PSRAPSRTPGPPSAQSSPID---A 1127
SP++ SP +PT+ P S P+ P + PP+ +SP A
Sbjct: 111 ---ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVA 167
Query: 1128 QPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP-----APTRKEFG 1182
+ + + P P EPK V P P P PP + P
Sbjct: 168 ESGSVITLSAPIAPSEPKTNL--NKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQS 225
Query: 1183 GIGA-PPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGP--GPAGYSTARPTIP- 1238
G+ + P + + +P+ TT + Q L GP PA S + ++P
Sbjct: 226 GVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV 285
Query: 1239 ----PRAGVISAPQSHARASAGRLTPESQSKTSETS----KGSTFLPEPL---------K 1281
+ + P + L P QS G + L +P
Sbjct: 286 VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSS 345
Query: 1282 PQAAFPPQSSLPPPAQRLQEPL------VPVAAPMPQSGP 1315
A++P Q S+ PP E + PV AP GP
Sbjct: 346 TGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGP 385
Score = 35.0 bits (79), Expect = 0.49
Identities = 50/191 (26%), Positives = 78/191 (40%), Gaps = 25/191 (13%)
Query: 1027 IALPSSTSSTLLGEDAEVA-----ADFDMEGDVDDYSAEVEELLPQHLQPSSSSGLGTSP 1081
+ + +S T G+DA + A + + +A E++LP+ P S+S
Sbjct: 1739 LPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK---PESAS-----V 1790
Query: 1082 SSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG----PPSAQSSPIDAQPATPLPQKD 1137
S++P SP S ++ PVP+LP + PS +PG PS +P D PL
Sbjct: 1791 SAAP--SPPVSLPLAPSPVPTLPPKQQFLPS-SPGLVLESPSKPLAPADEDELLPL---I 1844
Query: 1138 PAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREM 1197
P +P+ P V PT P P P A+ P + G + V E
Sbjct: 1845 PPEPISGGVPFQSVLVNMPT-PKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELE- 1902
Query: 1198 EAPKSPGTTRK 1208
E + TT++
Sbjct: 1903 EQDSTQATTQQ 1913
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 89.7 bits (221), Expect = 2e-17
Identities = 87/295 (29%), Positives = 111/295 (37%), Gaps = 42/295 (14%)
Query: 1074 SSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPP-----SAQSSPI 1125
SS + S SP +GP P + P P P + GPP Q P
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP 73
Query: 1126 DAQPATPLPQKDPAQ-----PLEPKRPPPP---RPVAPPTRPAPPQRPPPPSGARSPAPT 1177
+P P PQ D ++ P +P+ PPP +P PP P PQ PPP G R P
Sbjct: 74 PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP 133
Query: 1178 RKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQ-PSPQAGLAGPGPAGYSTARPT 1236
G P P + +P+SP G+ Q P PQ G GP
Sbjct: 134 PP-----GKPQGPPPQGDKSRSPRSPP-------GKPQGPPPQGGNQPQGPPPPPGKPQG 181
Query: 1237 IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1296
PP+ G PQ + P Q S +S+ P+ PQ PQ PPP
Sbjct: 182 PPPQGG--KKPQGPPPPGKPQ-GPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG 238
Query: 1297 QRLQEPLVPVAAPMPQSGPQPNLETPPQPPP-----RSRSSHSLPSEASSQPQQE 1346
+ P P PQ P P PQ PP +S+S+ S P + PQQE
Sbjct: 239 KPQGPP--PQGGNKPQGPPPPG---KPQGPPAQGGSKSQSARSPPGKPQGPPQQE 288
Score = 82.4 bits (202), Expect = 3e-15
Identities = 79/280 (28%), Positives = 103/280 (36%), Gaps = 42/280 (15%)
Query: 1071 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSA-----QS 1122
P G P SP P +GP P + P P P + GPP Q
Sbjct: 72 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131
Query: 1123 SPIDAQPATPLPQKDPAQ-----PLEPKRPPPP---RPVAPPTRPAPPQRPPPPSGAR-- 1172
P +P P PQ D ++ P +P+ PPP +P PP P PQ PPP G +
Sbjct: 132 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQ 191
Query: 1173 SPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYST 1232
P P K G PP G R ++P PG + P PQ G GP
Sbjct: 192 GPPPPGKPQG----PPPQGDKSRSSQSP--PGKPQG-------PPPQGGNQPQGPPPPPG 238
Query: 1233 ARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL 1292
PP+ G + PQ + P S++++ P+ Q PQ
Sbjct: 239 KPQGPPPQGG--NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP 296
Query: 1293 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSS 1332
PP Q+P P A QP + PP+PP R S
Sbjct: 297 PPAGGNPQQPQAPPAG-------QP--QGPPRPPQGGRPS 327
Score = 64.3 bits (155), Expect = 8e-10
Identities = 74/256 (28%), Positives = 86/256 (33%), Gaps = 71/256 (27%)
Query: 1119 SAQSSP--IDAQPATPLPQ---KDPAQPLEPKRP--PPPRPVAPPTRPAPPQRP--PPPS 1169
S + SP I P P PQ K P P +P PPP+ P P PP +P PPP
Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 83
Query: 1170 GARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAG 1229
G +S +P G PP G P+ P P P GP P G
Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGG------NQPQGP------------PPPPGKPQGPPPQG 125
Query: 1230 YSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQ 1289
+ RP PP G P S +P P KPQ
Sbjct: 126 GN--RPQGPPPPGKPQGPPPQGDKSRSPRSP------------------PGKPQ------ 159
Query: 1290 SSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPP-------------RSRSSHSLP 1336
PP Q +P P P GP P PQ PP +SRSS S P
Sbjct: 160 ---GPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP 216
Query: 1337 SEASSQPQQ--EQPSG 1350
+ P Q QP G
Sbjct: 217 GKPQGPPPQGGNQPQG 232
Score = 56.6 bits (135), Expect = 2e-07
Identities = 40/138 (28%), Positives = 49/138 (35%), Gaps = 7/138 (5%)
Query: 1071 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRTPGPPSAQSSPIDA 1127
P G P S P +GP P + P P P + GPP +
Sbjct: 194 PPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 253
Query: 1128 QPATPLPQKDPAQ---PLEPKRPPPPRPVAPPTRPAP-PQRPPPPSGARSPAPTRKEFGG 1183
P PQ PAQ + R PP +P PP + PQ PPPP+G P G
Sbjct: 254 PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 313
Query: 1184 IGAPPSPGVARREMEAPK 1201
PP P R P+
Sbjct: 314 PQGPPRPPQGGRPSRPPQ 331
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 89.0 bits (219), Expect = 3e-17
Identities = 66/253 (26%), Positives = 96/253 (37%), Gaps = 30/253 (11%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1138
T+ S+P T +PT ++ P P+ P P+ ++ P P + +S+P + P K P
Sbjct: 250 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 309
Query: 1139 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194
A P PK P P P P P PAP + P P+ + PAPT AP P
Sbjct: 310 A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--------APKKPAPTT 360
Query: 1195 REMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS 1254
+ AP +P +P+P P P PT A + +
Sbjct: 361 PKEPAPTTP----------KEPAPTT-TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409
Query: 1255 AGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
+ TP+ S T +T P P P+ P P P + P P +
Sbjct: 410 SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463
Query: 1315 PQPNLETPPQPPP 1327
+P TP +P P
Sbjct: 464 KKPAPTTPKEPAP 476
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/314 (23%), Positives = 118/314 (37%), Gaps = 42/314 (13%)
Query: 1071 PSSSSGLGTSPSS-SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQS-SPIDAQ 1128
P+++ T+P SP T+ +PT + P P+ P +P+ + P P + + +P +
Sbjct: 405 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 464
Query: 1129 PATPLPQKDPAQ-------PLEPKR--PPPPRPVAP--PTRPAP-------PQRP--PPP 1168
P K+PA P PK+ P P +AP P +PAP P P P P
Sbjct: 465 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 524
Query: 1169 SGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPA 1228
+ PAPT + P P + AP +P + P+ G A P
Sbjct: 525 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA---PT 581
Query: 1229 GYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP- 1287
PT P + AP+ A + T + K + T+ T P +P P
Sbjct: 582 TLKEPAPTTPKK----PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 637
Query: 1288 ------PQSSLP-----PPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP 1336
P+ + P P ++P AP GP P P ++ + P
Sbjct: 638 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 697
Query: 1337 SE-ASSQPQQEQPS 1349
E A + P++ P+
Sbjct: 698 KEPAPTTPKKPAPT 711
Score = 75.5 bits (184), Expect = 3e-13
Identities = 66/287 (22%), Positives = 108/287 (37%), Gaps = 24/287 (8%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQ-SPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
P+ P++ T+P T+P + +PT + P P+ P P+ ++ P P + +
Sbjct: 330 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 389
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPT--RPAPPQ-RPPPPSGARSPAPTRKEF 1181
+ P K+PA P P+ +P T PAP + P P+ + PAPT +
Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449
Query: 1182 GGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
P P + AP +P +P+P P PT P +
Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTP----------KEPAPTTP-KETAPTTPKKLTPTTPEKL 498
Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
+ P+ A + L P + + + T+ P P P+AA P P P
Sbjct: 499 AP-TTPEKPAPTTPEELAPTTPEEPTPTTPEE---PAPTTPKAAAPNTPKEPAPT----T 550
Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQP 1348
P P + P ET P P+ + +L A + P++ P
Sbjct: 551 PKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEPAPTTPKKPAP 596
Score = 72.4 bits (176), Expect = 3e-12
Identities = 72/293 (24%), Positives = 114/293 (38%), Gaps = 31/293 (10%)
Query: 1079 TSPSSSPRTSPCQ-SPTISEGPVPSLPIRPS-----RAPSRT--PGPPSAQSSPIDAQPA 1130
T+P T+P + +PT ++ P P+ P P+ AP+ T P P + +S+P +
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418
Query: 1131 TPLPQKDPAQPLEPKRPPPPRPVAP-PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPS 1189
+P K+PA P PK P P P P PT P + P P+ + PAPT + P
Sbjct: 419 SPTTTKEPA-PTTPKEPAPTTPKKPAPTTP----KEPAPTTPKEPAPTTTKKPAPTTPKE 473
Query: 1190 PGVARREMEAPKSP---GTTRKDNIGRSQPSPQAGLAGP--GPAGYSTARPTIP------ 1238
P + AP +P T + + + P A P PT P
Sbjct: 474 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 533
Query: 1239 -PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ 1297
P+A + P+ A + P + + + T+ T P P+ P P P
Sbjct: 534 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET---APTTPKGTAPTTLKEPAPTT 590
Query: 1298 RLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE-ASSQPQQEQPS 1349
++P AP P P P ++ + P E A + P++ P+
Sbjct: 591 P-KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 642
Score = 69.7 bits (169), Expect = 2e-11
Identities = 75/318 (23%), Positives = 113/318 (35%), Gaps = 61/318 (19%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS----AQSSPIDAQPATP-- 1132
T +P T +PT + P P+ P P+ ++ P P + A ++P + P TP
Sbjct: 430 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 489
Query: 1133 ----LPQKDPAQPLEPKRPPP--PRPVAPPT----RPAPPQRPPP-------PSGARSPA 1175
P+K P P++P P P +AP T P P+ P P P+ + PA
Sbjct: 490 LTPTTPEK--LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 547
Query: 1176 PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP 1235
PT + P P + AP +P T + P+ A A +T P
Sbjct: 548 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 607
Query: 1236 T---------IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF 1286
T P+ + P+ A TP+ + T+ T L EP
Sbjct: 608 TSTTCDKPAPTTPKGTAPTTPKEPAPT-----TPKEPAPTTPKGTAPTTLKEPAPTTPKK 662
Query: 1287 PPQSSLPP-------------PAQRLQEPLVPVAA--PMPQSGPQPNLETPPQPPPRSRS 1331
P L P PA + P P P + +P TP PPP +
Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-- 720
Query: 1332 SHSLPSEASSQPQQEQPS 1349
SE S+ ++P+
Sbjct: 721 -----SEVSTPTTTKEPT 733
Score = 66.2 bits (160), Expect = 2e-10
Identities = 69/291 (23%), Positives = 103/291 (35%), Gaps = 30/291 (10%)
Query: 1070 QPSSSSGLGTSPSSSPRTSPCQ----SPTISEGPVPSLP--IRPSRAPSRTPGPPSAQSS 1123
+P+ ++ T+P++ + +P +PT E P P+ P + P+ TP P + +
Sbjct: 473 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE-EPA 531
Query: 1124 PIDAQPATPLPQKDPAQPLEPKRPPPPRPVAP-PTRPAPPQRPPP----PSGARSPAPTR 1178
P + A P K+PA P PK P P P P PT P P P+ + PAPT
Sbjct: 532 PTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT- 589
Query: 1179 KEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAG--PGPAGYSTARPT 1236
P P K P +T D + P A P P PT
Sbjct: 590 -------TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 642
Query: 1237 IP----PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL 1292
P P AP + + + L P + + T+ P P P+ P
Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK---PAPTTPKETAPTTPKE 699
Query: 1293 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQP 1343
P P + P P + T +P +S E S++P
Sbjct: 700 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 750
Score = 64.7 bits (156), Expect = 6e-10
Identities = 58/270 (21%), Positives = 91/270 (33%), Gaps = 55/270 (20%)
Query: 1067 QHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPID 1126
Q ++ +S+ L + + +P ++ T ++GP + P P+ P+ P
Sbjct: 177 QSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT---------PTTPKEPAS 226
Query: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQ----RPPPPSGARSPAPTRKEFG 1182
P P P + P PK P P + PT P P + P P+ + PAPT +
Sbjct: 227 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK-- 284
Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1242
P+P + PK P T P P PT P
Sbjct: 285 ----EPAPTTTKSAPTTPKEPAPTTPKK--------------PAPTTPKEPAPTTPKEP- 325
Query: 1243 VISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEP 1302
TP + + + T+K P P P+ P P P +
Sbjct: 326 ----------------TPTTPKEPAPTTKE----PAPTTPKEPAPTAPKKPAPTTPKEPA 365
Query: 1303 LVPVAAPMPQSGPQPNLETPPQPPPRSRSS 1332
P P + +P+ TP +P P + S
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 395
Score = 53.1 bits (126), Expect = 2e-06
Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 53/240 (22%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSR---APSRTPGPPS------AQSSPIDAQP 1129
T ++P T +PT + P P+ P +P+ AP+ T P S A ++P P
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625
Query: 1130 ATPLPQKDPAQPLEPKRPPP--PRPVAPPT--RPAP--PQRPPPPSGA------------ 1171
TP K+PA P PK P P P+ AP T PAP P++P P A
Sbjct: 626 TTP---KEPA-PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681
Query: 1172 RSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYS 1231
PAPT + P P + AP +P T S P+ +
Sbjct: 682 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-------------T 728
Query: 1232 TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
T PT ++ S P+ L+ E K E S +P P A P ++
Sbjct: 729 TKEPTTIHKSPDESTPE---------LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 779
Score = 40.0 bits (92), Expect = 0.015
Identities = 63/309 (20%), Positives = 111/309 (35%), Gaps = 55/309 (17%)
Query: 1066 PQHLQPSSSSG--LGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS--------------R 1109
P+ L P+++ G TS +P T +PT + P P+ P +P+
Sbjct: 665 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 724
Query: 1110 APSRTPGPPSAQSSPIDAQP---ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1166
P+ T P + SP ++ P A P P+ P EP P P A +P
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA--------TKPE 776
Query: 1167 PPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPG 1226
+ A+ R + P A +P T++ + + A
Sbjct: 777 MTTTAKDKTTER----DLRTTPETTTA--------APKMTKETATTTEKTTESKITATTT 824
Query: 1227 PAGYSTARPTIPPRAGVISAPQSHARASAGR---LTPESQSKTSETSK-------GSTFL 1276
+T + T P + + + + + T E +K ET+K
Sbjct: 825 QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATT 884
Query: 1277 PEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP 1336
P+P KP A P+ P + + + + V P P+ T P+ P SR + ++
Sbjct: 885 PKPQKPTKA--PKK---PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAM- 938
Query: 1337 SEASSQPQQ 1345
+ +++P Q
Sbjct: 939 LQTTTRPNQ 947
Score = 33.1 bits (74), Expect = 1.9
Identities = 49/247 (19%), Positives = 86/247 (34%), Gaps = 21/247 (8%)
Query: 1008 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1057
KSPD E+S E AL +S T + E A D E D+
Sbjct: 737 KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 792
Query: 1058 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1114
+ E P+ + ++++ T+ S T+ + T ++ P + + AP T
Sbjct: 793 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 852
Query: 1115 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP 1174
+ ++ I +P KD A + P P +P P +P ++P R P
Sbjct: 853 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 912
Query: 1175 --APTRKEFGGI--GAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
PT ++ P+ +A ++ P T + P + G +
Sbjct: 913 KTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPH 972
Query: 1231 STARPTI 1237
RP +
Sbjct: 973 MLLRPHV 979
Score = 32.0 bits (71), Expect = 4.1
Identities = 26/122 (21%), Positives = 46/122 (37%), Gaps = 5/122 (4%)
Query: 1232 TARPTIPPRAGVISAPQSHARASA---GRLTPESQSKTSETSKGSTFLPEPLKPQAAFPP 1288
T+ + P + V++ P A + TP+ + T+ ST EP P
Sbjct: 182 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 241
Query: 1289 QSSLPP-PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQ 1347
+ P P P P P P + +P TP +P P + + + S+ ++
Sbjct: 242 TTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300
Query: 1348 PS 1349
P+
Sbjct: 301 PA 302
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 89.0 bits (219), Expect = 3e-17
Identities = 66/253 (26%), Positives = 96/253 (37%), Gaps = 30/253 (11%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1138
T+ S+P T +PT ++ P P+ P P+ ++ P P + +S+P + P K P
Sbjct: 291 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 350
Query: 1139 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194
A P PK P P P P P PAP + P P+ + PAPT AP P
Sbjct: 351 A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--------APKKPAPTT 401
Query: 1195 REMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS 1254
+ AP +P +P+P P P PT A + +
Sbjct: 402 PKEPAPTTP----------KEPAPTT-TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450
Query: 1255 AGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
+ TP+ S T +T P P P+ P P P + P P +
Sbjct: 451 SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504
Query: 1315 PQPNLETPPQPPP 1327
+P TP +P P
Sbjct: 505 KKPAPTTPKEPAP 517
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/314 (23%), Positives = 118/314 (37%), Gaps = 42/314 (13%)
Query: 1071 PSSSSGLGTSPSS-SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQS-SPIDAQ 1128
P+++ T+P SP T+ +PT + P P+ P +P+ + P P + + +P +
Sbjct: 446 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 505
Query: 1129 PATPLPQKDPAQ-------PLEPKR--PPPPRPVAP--PTRPAP-------PQRP--PPP 1168
P K+PA P PK+ P P +AP P +PAP P P P P
Sbjct: 506 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 565
Query: 1169 SGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPA 1228
+ PAPT + P P + AP +P + P+ G A P
Sbjct: 566 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA---PT 622
Query: 1229 GYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP- 1287
PT P + AP+ A + T + K + T+ T P +P P
Sbjct: 623 TLKEPAPTTPKK----PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 678
Query: 1288 ------PQSSLP-----PPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP 1336
P+ + P P ++P AP GP P P ++ + P
Sbjct: 679 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 738
Query: 1337 SE-ASSQPQQEQPS 1349
E A + P++ P+
Sbjct: 739 KEPAPTTPKKPAPT 752
Score = 75.5 bits (184), Expect = 3e-13
Identities = 66/287 (22%), Positives = 108/287 (37%), Gaps = 24/287 (8%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQ-SPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
P+ P++ T+P T+P + +PT + P P+ P P+ ++ P P + +
Sbjct: 371 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 430
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPT--RPAPPQ-RPPPPSGARSPAPTRKEF 1181
+ P K+PA P P+ +P T PAP + P P+ + PAPT +
Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490
Query: 1182 GGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
P P + AP +P +P+P P PT P +
Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTP----------KEPAPTTP-KETAPTTPKKLTPTTPEKL 539
Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
+ P+ A + L P + + + T+ P P P+AA P P P
Sbjct: 540 AP-TTPEKPAPTTPEELAPTTPEEPTPTTPEE---PAPTTPKAAAPNTPKEPAPT----T 591
Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQP 1348
P P + P ET P P+ + +L A + P++ P
Sbjct: 592 PKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEPAPTTPKKPAP 637
Score = 72.4 bits (176), Expect = 3e-12
Identities = 72/293 (24%), Positives = 114/293 (38%), Gaps = 31/293 (10%)
Query: 1079 TSPSSSPRTSPCQ-SPTISEGPVPSLPIRPS-----RAPSRT--PGPPSAQSSPIDAQPA 1130
T+P T+P + +PT ++ P P+ P P+ AP+ T P P + +S+P +
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459
Query: 1131 TPLPQKDPAQPLEPKRPPPPRPVAP-PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPS 1189
+P K+PA P PK P P P P PT P + P P+ + PAPT + P
Sbjct: 460 SPTTTKEPA-PTTPKEPAPTTPKKPAPTTP----KEPAPTTPKEPAPTTTKKPAPTTPKE 514
Query: 1190 PGVARREMEAPKSP---GTTRKDNIGRSQPSPQAGLAGP--GPAGYSTARPTIP------ 1238
P + AP +P T + + + P A P PT P
Sbjct: 515 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 574
Query: 1239 -PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ 1297
P+A + P+ A + P + + + T+ T P P+ P P P
Sbjct: 575 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET---APTTPKGTAPTTLKEPAPTT 631
Query: 1298 RLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE-ASSQPQQEQPS 1349
++P AP P P P ++ + P E A + P++ P+
Sbjct: 632 P-KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 683
Score = 69.7 bits (169), Expect = 2e-11
Identities = 75/318 (23%), Positives = 113/318 (35%), Gaps = 61/318 (19%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS----AQSSPIDAQPATP-- 1132
T +P T +PT + P P+ P P+ ++ P P + A ++P + P TP
Sbjct: 471 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 530
Query: 1133 ----LPQKDPAQPLEPKRPPP--PRPVAPPT----RPAPPQRPPP-------PSGARSPA 1175
P+K P P++P P P +AP T P P+ P P P+ + PA
Sbjct: 531 LTPTTPEK--LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 588
Query: 1176 PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP 1235
PT + P P + AP +P T + P+ A A +T P
Sbjct: 589 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 648
Query: 1236 T---------IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF 1286
T P+ + P+ A TP+ + T+ T L EP
Sbjct: 649 TSTTCDKPAPTTPKGTAPTTPKEPAPT-----TPKEPAPTTPKGTAPTTLKEPAPTTPKK 703
Query: 1287 PPQSSLPP-------------PAQRLQEPLVPVAA--PMPQSGPQPNLETPPQPPPRSRS 1331
P L P PA + P P P + +P TP PPP +
Sbjct: 704 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-- 761
Query: 1332 SHSLPSEASSQPQQEQPS 1349
SE S+ ++P+
Sbjct: 762 -----SEVSTPTTTKEPT 774
Score = 66.2 bits (160), Expect = 2e-10
Identities = 69/291 (23%), Positives = 103/291 (35%), Gaps = 30/291 (10%)
Query: 1070 QPSSSSGLGTSPSSSPRTSPCQ----SPTISEGPVPSLP--IRPSRAPSRTPGPPSAQSS 1123
+P+ ++ T+P++ + +P +PT E P P+ P + P+ TP P + +
Sbjct: 514 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE-EPA 572
Query: 1124 PIDAQPATPLPQKDPAQPLEPKRPPPPRPVAP-PTRPAPPQRPPP----PSGARSPAPTR 1178
P + A P K+PA P PK P P P P PT P P P+ + PAPT
Sbjct: 573 PTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT- 630
Query: 1179 KEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAG--PGPAGYSTARPT 1236
P P K P +T D + P A P P PT
Sbjct: 631 -------TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 683
Query: 1237 IP----PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL 1292
P P AP + + + L P + + T+ P P P+ P
Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK---PAPTTPKETAPTTPKE 740
Query: 1293 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQP 1343
P P + P P + T +P +S E S++P
Sbjct: 741 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 791
Score = 64.7 bits (156), Expect = 6e-10
Identities = 58/270 (21%), Positives = 91/270 (33%), Gaps = 55/270 (20%)
Query: 1067 QHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPID 1126
Q ++ +S+ L + + +P ++ T ++GP + P P+ P+ P
Sbjct: 218 QSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT---------PTTPKEPAS 267
Query: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQ----RPPPPSGARSPAPTRKEFG 1182
P P P + P PK P P + PT P P + P P+ + PAPT +
Sbjct: 268 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK-- 325
Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1242
P+P + PK P T P P PT P
Sbjct: 326 ----EPAPTTTKSAPTTPKEPAPTTPKK--------------PAPTTPKEPAPTTPKEP- 366
Query: 1243 VISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEP 1302
TP + + + T+K P P P+ P P P +
Sbjct: 367 ----------------TPTTPKEPAPTTKE----PAPTTPKEPAPTAPKKPAPTTPKEPA 406
Query: 1303 LVPVAAPMPQSGPQPNLETPPQPPPRSRSS 1332
P P + +P+ TP +P P + S
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 436
Score = 53.1 bits (126), Expect = 2e-06
Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 53/240 (22%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSR---APSRTPGPPS------AQSSPIDAQP 1129
T ++P T +PT + P P+ P +P+ AP+ T P S A ++P P
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666
Query: 1130 ATPLPQKDPAQPLEPKRPPP--PRPVAPPT--RPAP--PQRPPPPSGA------------ 1171
TP K+PA P PK P P P+ AP T PAP P++P P A
Sbjct: 667 TTP---KEPA-PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722
Query: 1172 RSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYS 1231
PAPT + P P + AP +P T S P+ +
Sbjct: 723 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-------------T 769
Query: 1232 TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
T PT ++ S P+ L+ E K E S +P P A P ++
Sbjct: 770 TKEPTTIHKSPDESTPE---------LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 820
Score = 40.0 bits (92), Expect = 0.015
Identities = 63/309 (20%), Positives = 111/309 (35%), Gaps = 55/309 (17%)
Query: 1066 PQHLQPSSSSG--LGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS--------------R 1109
P+ L P+++ G TS +P T +PT + P P+ P +P+
Sbjct: 706 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 765
Query: 1110 APSRTPGPPSAQSSPIDAQP---ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1166
P+ T P + SP ++ P A P P+ P EP P P A +P
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA--------TKPE 817
Query: 1167 PPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPG 1226
+ A+ R + P A +P T++ + + A
Sbjct: 818 MTTTAKDKTTER----DLRTTPETTTA--------APKMTKETATTTEKTTESKITATTT 865
Query: 1227 PAGYSTARPTIPPRAGVISAPQSHARASAGR---LTPESQSKTSETSK-------GSTFL 1276
+T + T P + + + + + T E +K ET+K
Sbjct: 866 QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATT 925
Query: 1277 PEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP 1336
P+P KP A P+ P + + + + V P P+ T P+ P SR + ++
Sbjct: 926 PKPQKPTKA--PKK---PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAM- 979
Query: 1337 SEASSQPQQ 1345
+ +++P Q
Sbjct: 980 LQTTTRPNQ 988
Score = 33.1 bits (74), Expect = 1.9
Identities = 49/247 (19%), Positives = 86/247 (34%), Gaps = 21/247 (8%)
Query: 1008 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1057
KSPD E+S E AL +S T + E A D E D+
Sbjct: 778 KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 833
Query: 1058 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1114
+ E P+ + ++++ T+ S T+ + T ++ P + + AP T
Sbjct: 834 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 893
Query: 1115 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP 1174
+ ++ I +P KD A + P P +P P +P ++P R P
Sbjct: 894 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 953
Query: 1175 --APTRKEFGGI--GAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
PT ++ P+ +A ++ P T + P + G +
Sbjct: 954 KTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPH 1013
Query: 1231 STARPTI 1237
RP +
Sbjct: 1014 MLLRPHV 1020
Score = 32.0 bits (71), Expect = 4.1
Identities = 26/122 (21%), Positives = 46/122 (37%), Gaps = 5/122 (4%)
Query: 1232 TARPTIPPRAGVISAPQSHARASA---GRLTPESQSKTSETSKGSTFLPEPLKPQAAFPP 1288
T+ + P + V++ P A + TP+ + T+ ST EP P
Sbjct: 223 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 282
Query: 1289 QSSLPP-PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQ 1347
+ P P P P P P + +P TP +P P + + + S+ ++
Sbjct: 283 TTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341
Query: 1348 PS 1349
P+
Sbjct: 342 PA 343
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 89.0 bits (219), Expect = 3e-17
Identities = 66/253 (26%), Positives = 96/253 (37%), Gaps = 30/253 (11%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1138
T+ S+P T +PT ++ P P+ P P+ ++ P P + +S+P + P K P
Sbjct: 343 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402
Query: 1139 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194
A P PK P P P P P PAP + P P+ + PAPT AP P
Sbjct: 403 A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--------APKKPAPTT 453
Query: 1195 REMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS 1254
+ AP +P +P+P P P PT A + +
Sbjct: 454 PKEPAPTTP----------KEPAPTT-TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502
Query: 1255 AGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
+ TP+ S T +T P P P+ P P P + P P +
Sbjct: 503 SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556
Query: 1315 PQPNLETPPQPPP 1327
+P TP +P P
Sbjct: 557 KKPAPTTPKEPAP 569
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/314 (23%), Positives = 118/314 (37%), Gaps = 42/314 (13%)
Query: 1071 PSSSSGLGTSPSS-SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQS-SPIDAQ 1128
P+++ T+P SP T+ +PT + P P+ P +P+ + P P + + +P +
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 557
Query: 1129 PATPLPQKDPAQ-------PLEPKR--PPPPRPVAP--PTRPAP-------PQRP--PPP 1168
P K+PA P PK+ P P +AP P +PAP P P P P
Sbjct: 558 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617
Query: 1169 SGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPA 1228
+ PAPT + P P + AP +P + P+ G A P
Sbjct: 618 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA---PT 674
Query: 1229 GYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP- 1287
PT P + AP+ A + T + K + T+ T P +P P
Sbjct: 675 TLKEPAPTTPKK----PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730
Query: 1288 ------PQSSLP-----PPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP 1336
P+ + P P ++P AP GP P P ++ + P
Sbjct: 731 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 790
Query: 1337 SE-ASSQPQQEQPS 1349
E A + P++ P+
Sbjct: 791 KEPAPTTPKKPAPT 804
Score = 75.5 bits (184), Expect = 3e-13
Identities = 66/287 (22%), Positives = 108/287 (37%), Gaps = 24/287 (8%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQ-SPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
P+ P++ T+P T+P + +PT + P P+ P P+ ++ P P + +
Sbjct: 423 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 482
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPT--RPAPPQ-RPPPPSGARSPAPTRKEF 1181
+ P K+PA P P+ +P T PAP + P P+ + PAPT +
Sbjct: 483 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 542
Query: 1182 GGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
P P + AP +P +P+P P PT P +
Sbjct: 543 PAPTTPKEPAPTTTKKPAPTTP----------KEPAPTTP-KETAPTTPKKLTPTTPEKL 591
Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
+ P+ A + L P + + + T+ P P P+AA P P P
Sbjct: 592 AP-TTPEKPAPTTPEELAPTTPEEPTPTTPEE---PAPTTPKAAAPNTPKEPAPT----T 643
Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQP 1348
P P + P ET P P+ + +L A + P++ P
Sbjct: 644 PKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEPAPTTPKKPAP 689
Score = 72.4 bits (176), Expect = 3e-12
Identities = 72/293 (24%), Positives = 114/293 (38%), Gaps = 31/293 (10%)
Query: 1079 TSPSSSPRTSPCQ-SPTISEGPVPSLPIRPS-----RAPSRT--PGPPSAQSSPIDAQPA 1130
T+P T+P + +PT ++ P P+ P P+ AP+ T P P + +S+P +
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 1131 TPLPQKDPAQPLEPKRPPPPRPVAP-PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPS 1189
+P K+PA P PK P P P P PT P + P P+ + PAPT + P
Sbjct: 512 SPTTTKEPA-PTTPKEPAPTTPKKPAPTTP----KEPAPTTPKEPAPTTTKKPAPTTPKE 566
Query: 1190 PGVARREMEAPKSP---GTTRKDNIGRSQPSPQAGLAGP--GPAGYSTARPTIP------ 1238
P + AP +P T + + + P A P PT P
Sbjct: 567 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 626
Query: 1239 -PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ 1297
P+A + P+ A + P + + + T+ T P P+ P P P
Sbjct: 627 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET---APTTPKGTAPTTLKEPAPTT 683
Query: 1298 RLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE-ASSQPQQEQPS 1349
++P AP P P P ++ + P E A + P++ P+
Sbjct: 684 P-KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 735
Score = 69.7 bits (169), Expect = 2e-11
Identities = 75/318 (23%), Positives = 113/318 (35%), Gaps = 61/318 (19%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS----AQSSPIDAQPATP-- 1132
T +P T +PT + P P+ P P+ ++ P P + A ++P + P TP
Sbjct: 523 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 582
Query: 1133 ----LPQKDPAQPLEPKRPPP--PRPVAPPT----RPAPPQRPPP-------PSGARSPA 1175
P+K P P++P P P +AP T P P+ P P P+ + PA
Sbjct: 583 LTPTTPEK--LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 640
Query: 1176 PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP 1235
PT + P P + AP +P T + P+ A A +T P
Sbjct: 641 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 700
Query: 1236 T---------IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF 1286
T P+ + P+ A TP+ + T+ T L EP
Sbjct: 701 TSTTCDKPAPTTPKGTAPTTPKEPAPT-----TPKEPAPTTPKGTAPTTLKEPAPTTPKK 755
Query: 1287 PPQSSLPP-------------PAQRLQEPLVPVAA--PMPQSGPQPNLETPPQPPPRSRS 1331
P L P PA + P P P + +P TP PPP +
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-- 813
Query: 1332 SHSLPSEASSQPQQEQPS 1349
SE S+ ++P+
Sbjct: 814 -----SEVSTPTTTKEPT 826
Score = 66.2 bits (160), Expect = 2e-10
Identities = 69/291 (23%), Positives = 103/291 (35%), Gaps = 30/291 (10%)
Query: 1070 QPSSSSGLGTSPSSSPRTSPCQ----SPTISEGPVPSLP--IRPSRAPSRTPGPPSAQSS 1123
+P+ ++ T+P++ + +P +PT E P P+ P + P+ TP P + +
Sbjct: 566 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE-EPA 624
Query: 1124 PIDAQPATPLPQKDPAQPLEPKRPPPPRPVAP-PTRPAPPQRPPP----PSGARSPAPTR 1178
P + A P K+PA P PK P P P P PT P P P+ + PAPT
Sbjct: 625 PTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT- 682
Query: 1179 KEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAG--PGPAGYSTARPT 1236
P P K P +T D + P A P P PT
Sbjct: 683 -------TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 735
Query: 1237 IP----PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL 1292
P P AP + + + L P + + T+ P P P+ P
Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK---PAPTTPKETAPTTPKE 792
Query: 1293 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQP 1343
P P + P P + T +P +S E S++P
Sbjct: 793 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 843
Score = 64.7 bits (156), Expect = 6e-10
Identities = 58/270 (21%), Positives = 91/270 (33%), Gaps = 55/270 (20%)
Query: 1067 QHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPID 1126
Q ++ +S+ L + + +P ++ T ++GP + P P+ P+ P
Sbjct: 270 QSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT---------PTTPKEPAS 319
Query: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQ----RPPPPSGARSPAPTRKEFG 1182
P P P + P PK P P + PT P P + P P+ + PAPT +
Sbjct: 320 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK-- 377
Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1242
P+P + PK P T P P PT P
Sbjct: 378 ----EPAPTTTKSAPTTPKEPAPTTPKK--------------PAPTTPKEPAPTTPKEP- 418
Query: 1243 VISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEP 1302
TP + + + T+K P P P+ P P P +
Sbjct: 419 ----------------TPTTPKEPAPTTKE----PAPTTPKEPAPTAPKKPAPTTPKEPA 458
Query: 1303 LVPVAAPMPQSGPQPNLETPPQPPPRSRSS 1332
P P + +P+ TP +P P + S
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 488
Score = 53.1 bits (126), Expect = 2e-06
Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 53/240 (22%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSR---APSRTPGPPS------AQSSPIDAQP 1129
T ++P T +PT + P P+ P +P+ AP+ T P S A ++P P
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718
Query: 1130 ATPLPQKDPAQPLEPKRPPP--PRPVAPPT--RPAP--PQRPPPPSGA------------ 1171
TP K+PA P PK P P P+ AP T PAP P++P P A
Sbjct: 719 TTP---KEPA-PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774
Query: 1172 RSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYS 1231
PAPT + P P + AP +P T S P+ +
Sbjct: 775 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-------------T 821
Query: 1232 TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
T PT ++ S P+ L+ E K E S +P P A P ++
Sbjct: 822 TKEPTTIHKSPDESTPE---------LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 872
Score = 40.0 bits (92), Expect = 0.015
Identities = 63/309 (20%), Positives = 111/309 (35%), Gaps = 55/309 (17%)
Query: 1066 PQHLQPSSSSG--LGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS--------------R 1109
P+ L P+++ G TS +P T +PT + P P+ P +P+
Sbjct: 758 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 817
Query: 1110 APSRTPGPPSAQSSPIDAQP---ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1166
P+ T P + SP ++ P A P P+ P EP P P A +P
Sbjct: 818 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA--------TKPE 869
Query: 1167 PPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPG 1226
+ A+ R + P A +P T++ + + A
Sbjct: 870 MTTTAKDKTTER----DLRTTPETTTA--------APKMTKETATTTEKTTESKITATTT 917
Query: 1227 PAGYSTARPTIPPRAGVISAPQSHARASAGR---LTPESQSKTSETSK-------GSTFL 1276
+T + T P + + + + + T E +K ET+K
Sbjct: 918 QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATT 977
Query: 1277 PEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP 1336
P+P KP A P+ P + + + + V P P+ T P+ P SR + ++
Sbjct: 978 PKPQKPTKA--PKK---PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAM- 1031
Query: 1337 SEASSQPQQ 1345
+ +++P Q
Sbjct: 1032 LQTTTRPNQ 1040
Score = 33.1 bits (74), Expect = 1.9
Identities = 49/247 (19%), Positives = 86/247 (34%), Gaps = 21/247 (8%)
Query: 1008 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1057
KSPD E+S E AL +S T + E A D E D+
Sbjct: 830 KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 885
Query: 1058 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1114
+ E P+ + ++++ T+ S T+ + T ++ P + + AP T
Sbjct: 886 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 945
Query: 1115 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP 1174
+ ++ I +P KD A + P P +P P +P ++P R P
Sbjct: 946 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 1005
Query: 1175 --APTRKEFGGI--GAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
PT ++ P+ +A ++ P T + P + G +
Sbjct: 1006 KTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPH 1065
Query: 1231 STARPTI 1237
RP +
Sbjct: 1066 MLLRPHV 1072
Score = 32.0 bits (71), Expect = 4.1
Identities = 26/122 (21%), Positives = 46/122 (37%), Gaps = 5/122 (4%)
Query: 1232 TARPTIPPRAGVISAPQSHARASA---GRLTPESQSKTSETSKGSTFLPEPLKPQAAFPP 1288
T+ + P + V++ P A + TP+ + T+ ST EP P
Sbjct: 275 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 334
Query: 1289 QSSLPP-PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQ 1347
+ P P P P P P + +P TP +P P + + + S+ ++
Sbjct: 335 TTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393
Query: 1348 PS 1349
P+
Sbjct: 394 PA 395
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 89.0 bits (219), Expect = 3e-17
Identities = 66/253 (26%), Positives = 96/253 (37%), Gaps = 30/253 (11%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDP 1138
T+ S+P T +PT ++ P P+ P P+ ++ P P + +S+P + P K P
Sbjct: 384 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443
Query: 1139 AQPLEPKRPPPPRPVAP----PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVAR 1194
A P PK P P P P P PAP + P P+ + PAPT AP P
Sbjct: 444 A-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT--------APKKPAPTT 494
Query: 1195 REMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARAS 1254
+ AP +P +P+P P P PT A + +
Sbjct: 495 PKEPAPTTP----------KEPAPTT-TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543
Query: 1255 AGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSG 1314
+ TP+ S T +T P P P+ P P P + P P +
Sbjct: 544 SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597
Query: 1315 PQPNLETPPQPPP 1327
+P TP +P P
Sbjct: 598 KKPAPTTPKEPAP 610
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/314 (23%), Positives = 118/314 (37%), Gaps = 42/314 (13%)
Query: 1071 PSSSSGLGTSPSS-SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQS-SPIDAQ 1128
P+++ T+P SP T+ +PT + P P+ P +P+ + P P + + +P +
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 598
Query: 1129 PATPLPQKDPAQ-------PLEPKR--PPPPRPVAP--PTRPAP-------PQRP--PPP 1168
P K+PA P PK+ P P +AP P +PAP P P P P
Sbjct: 599 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 658
Query: 1169 SGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPA 1228
+ PAPT + P P + AP +P + P+ G A P
Sbjct: 659 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA---PT 715
Query: 1229 GYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFP- 1287
PT P + AP+ A + T + K + T+ T P +P P
Sbjct: 716 TLKEPAPTTPKK----PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771
Query: 1288 ------PQSSLP-----PPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP 1336
P+ + P P ++P AP GP P P ++ + P
Sbjct: 772 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 831
Query: 1337 SE-ASSQPQQEQPS 1349
E A + P++ P+
Sbjct: 832 KEPAPTTPKKPAPT 845
Score = 75.5 bits (184), Expect = 3e-13
Identities = 66/287 (22%), Positives = 108/287 (37%), Gaps = 24/287 (8%)
Query: 1066 PQHLQPSSSSGLGTSPSSSPRTSPCQ-SPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
P+ P++ T+P T+P + +PT + P P+ P P+ ++ P P + +
Sbjct: 464 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA 523
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPT--RPAPPQ-RPPPPSGARSPAPTRKEF 1181
+ P K+PA P P+ +P T PAP + P P+ + PAPT +
Sbjct: 524 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 583
Query: 1182 GGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
P P + AP +P +P+P P PT P +
Sbjct: 584 PAPTTPKEPAPTTTKKPAPTTP----------KEPAPTTP-KETAPTTPKKLTPTTPEKL 632
Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
+ P+ A + L P + + + T+ P P P+AA P P P
Sbjct: 633 AP-TTPEKPAPTTPEELAPTTPEEPTPTTPEE---PAPTTPKAAAPNTPKEPAPT----T 684
Query: 1302 PLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQP 1348
P P + P ET P P+ + +L A + P++ P
Sbjct: 685 PKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEPAPTTPKKPAP 730
Score = 72.4 bits (176), Expect = 3e-12
Identities = 72/293 (24%), Positives = 114/293 (38%), Gaps = 31/293 (10%)
Query: 1079 TSPSSSPRTSPCQ-SPTISEGPVPSLPIRPS-----RAPSRT--PGPPSAQSSPIDAQPA 1130
T+P T+P + +PT ++ P P+ P P+ AP+ T P P + +S+P +
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 1131 TPLPQKDPAQPLEPKRPPPPRPVAP-PTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPS 1189
+P K+PA P PK P P P P PT P + P P+ + PAPT + P
Sbjct: 553 SPTTTKEPA-PTTPKEPAPTTPKKPAPTTP----KEPAPTTPKEPAPTTTKKPAPTTPKE 607
Query: 1190 PGVARREMEAPKSP---GTTRKDNIGRSQPSPQAGLAGP--GPAGYSTARPTIP------ 1238
P + AP +P T + + + P A P PT P
Sbjct: 608 PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPT 667
Query: 1239 -PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ 1297
P+A + P+ A + P + + + T+ T P P+ P P P
Sbjct: 668 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET---APTTPKGTAPTTLKEPAPTT 724
Query: 1298 RLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE-ASSQPQQEQPS 1349
++P AP P P P ++ + P E A + P++ P+
Sbjct: 725 P-KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 776
Score = 69.7 bits (169), Expect = 2e-11
Identities = 75/318 (23%), Positives = 113/318 (35%), Gaps = 61/318 (19%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS----AQSSPIDAQPATP-- 1132
T +P T +PT + P P+ P P+ ++ P P + A ++P + P TP
Sbjct: 564 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKK 623
Query: 1133 ----LPQKDPAQPLEPKRPPP--PRPVAPPT----RPAPPQRPPP-------PSGARSPA 1175
P+K P P++P P P +AP T P P+ P P P+ + PA
Sbjct: 624 LTPTTPEK--LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 681
Query: 1176 PTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP 1235
PT + P P + AP +P T + P+ A A +T P
Sbjct: 682 PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 741
Query: 1236 T---------IPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF 1286
T P+ + P+ A TP+ + T+ T L EP
Sbjct: 742 TSTTCDKPAPTTPKGTAPTTPKEPAPT-----TPKEPAPTTPKGTAPTTLKEPAPTTPKK 796
Query: 1287 PPQSSLPP-------------PAQRLQEPLVPVAA--PMPQSGPQPNLETPPQPPPRSRS 1331
P L P PA + P P P + +P TP PPP +
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTT-- 854
Query: 1332 SHSLPSEASSQPQQEQPS 1349
SE S+ ++P+
Sbjct: 855 -----SEVSTPTTTKEPT 867
Score = 66.2 bits (160), Expect = 2e-10
Identities = 69/291 (23%), Positives = 103/291 (35%), Gaps = 30/291 (10%)
Query: 1070 QPSSSSGLGTSPSSSPRTSPCQ----SPTISEGPVPSLP--IRPSRAPSRTPGPPSAQSS 1123
+P+ ++ T+P++ + +P +PT E P P+ P + P+ TP P + +
Sbjct: 607 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE-EPA 665
Query: 1124 PIDAQPATPLPQKDPAQPLEPKRPPPPRPVAP-PTRPAPPQRPPP----PSGARSPAPTR 1178
P + A P K+PA P PK P P P P PT P P P+ + PAPT
Sbjct: 666 PTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT- 723
Query: 1179 KEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAG--PGPAGYSTARPT 1236
P P K P +T D + P A P P PT
Sbjct: 724 -------TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 776
Query: 1237 IP----PRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSL 1292
P P AP + + + L P + + T+ P P P+ P
Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK---PAPTTPKETAPTTPKE 833
Query: 1293 PPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQP 1343
P P + P P + T +P +S E S++P
Sbjct: 834 PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEP 884
Score = 64.7 bits (156), Expect = 6e-10
Identities = 58/270 (21%), Positives = 91/270 (33%), Gaps = 55/270 (20%)
Query: 1067 QHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPID 1126
Q ++ +S+ L + + +P ++ T ++GP + P P+ P+ P
Sbjct: 311 QSIEKTSAKDLAPTSKVLAKPTP-KAETTTKGPALTTPKEPT---------PTTPKEPAS 360
Query: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQ----RPPPPSGARSPAPTRKEFG 1182
P P P + P PK P P + PT P P + P P+ + PAPT +
Sbjct: 361 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTK-- 418
Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1242
P+P + PK P T P P PT P
Sbjct: 419 ----EPAPTTTKSAPTTPKEPAPTTPKK--------------PAPTTPKEPAPTTPKEP- 459
Query: 1243 VISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEP 1302
TP + + + T+K P P P+ P P P +
Sbjct: 460 ----------------TPTTPKEPAPTTKE----PAPTTPKEPAPTAPKKPAPTTPKEPA 499
Query: 1303 LVPVAAPMPQSGPQPNLETPPQPPPRSRSS 1332
P P + +P+ TP +P P + S
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKS 529
Score = 53.1 bits (126), Expect = 2e-06
Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 53/240 (22%)
Query: 1079 TSPSSSPRTSPCQSPTISEGPVPSLPIRPSR---APSRTPGPPS------AQSSPIDAQP 1129
T ++P T +PT + P P+ P +P+ AP+ T P S A ++P P
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759
Query: 1130 ATPLPQKDPAQPLEPKRPPP--PRPVAPPT--RPAP--PQRPPPPSGA------------ 1171
TP K+PA P PK P P P+ AP T PAP P++P P A
Sbjct: 760 TTP---KEPA-PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815
Query: 1172 RSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYS 1231
PAPT + P P + AP +P T S P+ +
Sbjct: 816 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-------------T 862
Query: 1232 TARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1291
T PT ++ S P+ L+ E K E S +P P A P ++
Sbjct: 863 TKEPTTIHKSPDESTPE---------LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 913
Score = 40.0 bits (92), Expect = 0.015
Identities = 63/309 (20%), Positives = 111/309 (35%), Gaps = 55/309 (17%)
Query: 1066 PQHLQPSSSSG--LGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS--------------R 1109
P+ L P+++ G TS +P T +PT + P P+ P +P+
Sbjct: 799 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 858
Query: 1110 APSRTPGPPSAQSSPIDAQP---ATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1166
P+ T P + SP ++ P A P P+ P EP P P A +P
Sbjct: 859 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA--------TKPE 910
Query: 1167 PPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPG 1226
+ A+ R + P A +P T++ + + A
Sbjct: 911 MTTTAKDKTTER----DLRTTPETTTA--------APKMTKETATTTEKTTESKITATTT 958
Query: 1227 PAGYSTARPTIPPRAGVISAPQSHARASAGR---LTPESQSKTSETSK-------GSTFL 1276
+T + T P + + + + + T E +K ET+K
Sbjct: 959 QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATT 1018
Query: 1277 PEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP 1336
P+P KP A P+ P + + + + V P P+ T P+ P SR + ++
Sbjct: 1019 PKPQKPTKA--PKK---PTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAM- 1072
Query: 1337 SEASSQPQQ 1345
+ +++P Q
Sbjct: 1073 LQTTTRPNQ 1081
Score = 33.1 bits (74), Expect = 1.9
Identities = 49/247 (19%), Positives = 86/247 (34%), Gaps = 21/247 (8%)
Query: 1008 KSPDWIKNLEEEMSLEKISIALPSS----------TSSTLLGEDAEVAADFDMEGDVDDY 1057
KSPD E+S E AL +S T + E A D E D+
Sbjct: 871 KSPD---ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT- 926
Query: 1058 SAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVP---SLPIRPSRAPSRT 1114
+ E P+ + ++++ T+ S T+ + T ++ P + + AP T
Sbjct: 927 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVT 986
Query: 1115 PGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP 1174
+ ++ I +P KD A + P P +P P +P ++P R P
Sbjct: 987 TTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKP 1046
Query: 1175 --APTRKEFGGI--GAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
PT ++ P+ +A ++ P T + P + G +
Sbjct: 1047 KTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPH 1106
Query: 1231 STARPTI 1237
RP +
Sbjct: 1107 MLLRPHV 1113
Score = 32.0 bits (71), Expect = 4.1
Identities = 26/122 (21%), Positives = 46/122 (37%), Gaps = 5/122 (4%)
Query: 1232 TARPTIPPRAGVISAPQSHARASA---GRLTPESQSKTSETSKGSTFLPEPLKPQAAFPP 1288
T+ + P + V++ P A + TP+ + T+ ST EP P
Sbjct: 316 TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP 375
Query: 1289 QSSLPP-PAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQ 1347
+ P P P P P P + +P TP +P P + + + S+ ++
Sbjct: 376 TTPKEPAPTTTKSAPTTP-KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434
Query: 1348 PS 1349
P+
Sbjct: 435 PA 436
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 88.2 bits (217), Expect = 5e-17
Identities = 83/273 (30%), Positives = 111/273 (40%), Gaps = 39/273 (14%)
Query: 1097 EGPVPSLPIRPSRAPSR--TPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRP------- 1147
E PSLP PS+ P + TPG P AQ + + P P K PAQP +P
Sbjct: 292 ESVKPSLP-SPSKPPIQQPTPGKPPAQQP--GHEKSQPGPAKPPAQPSGLTKPLAQQPGT 348
Query: 1148 -----PPPRPVAPPTRPAPPQRPP-PPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPK 1201
PP PP +P P +PP +G+ P+ + + PP G + P
Sbjct: 349 VKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408
Query: 1202 SPGTTRKDNIGRSQP-SPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1260
P T +G +P + Q GL P A T P P G I A Q A G+ +
Sbjct: 409 KPPT---QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ----AGPGKTSA 461
Query: 1261 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP--PPAQRLQEPLVPVAAPMPQSGPQPN 1318
+ T S+ LP P KP PPQ P PP Q+ P P + P P
Sbjct: 462 QQTGPTKPPSQ----LPGPAKP----PPQQPGPAKPPPQQPGSAKPPSQQP-GSTKPPPQ 512
Query: 1319 LETPPQPPPRSRSSHSLPSE--ASSQPQQEQPS 1349
P +P P+ S PS+ S++P +QPS
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545
Score = 85.9 bits (211), Expect = 2e-16
Identities = 89/297 (29%), Positives = 118/297 (39%), Gaps = 41/297 (13%)
Query: 1066 PQHLQPSSSSGLGTSPS-SSPRTSPCQSPTISEGPVPSLPIRPSR-APSRTPGPPSAQSS 1123
PQ Q G PS SP P Q PT + P S+ P++ P PS +
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 1124 PIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP-SGARSPAPTRKEFG 1182
P+ QP T P P QP P PP +P P +PP +G+ P+ +
Sbjct: 341 PLAQQPGTVKP---PVQP--------PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQP-SPQAGLAGPGPAGYSTARPTIPPRA 1241
+ PP G + P P T + +G +P + Q GL P A T P P
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQ---VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGP 446
Query: 1242 GVISAPQSHARASAGRLT----PESQ----SKTSETSKGSTFLPEPLKPQAAFPPQ---- 1289
G I A Q+ ++ + T P SQ +K G P P +P +A PP
Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA-KPPPQQPGSAKPPSQQPG 505
Query: 1290 SSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPP-QPPPRSRSSHSLPSEASSQPQQ 1345
S+ PPP Q+P A P PQ QP PP Q P ++ S PS A QQ
Sbjct: 506 STKPPP----QQP--GPAKPSPQ---QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ 553
Score = 64.3 bits (155), Expect = 8e-10
Identities = 77/281 (27%), Positives = 107/281 (38%), Gaps = 63/281 (22%)
Query: 1099 PVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKD--PAQPL----EPKRPPP--- 1149
PVPS P + T ++SSP QP P+KD P Q L EPK+PPP
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSP---QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVK 708
Query: 1150 ---------PRPVAPP-----TRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARR 1195
+ PP ++PAPP+ P PS + AP + P P + +
Sbjct: 709 QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPS-EQDKAPVADD-----KPKQPKMVKP 762
Query: 1196 EMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP--TIPPRAGVISAPQSHA-- 1251
+ S T K +I S+ QA P +A+P + PP +S S A
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 1252 -RASAGRLT----PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPV 1306
AS ++ P S+SK + EP K Q P+ P
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK---------------PD 867
Query: 1307 AAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQ 1347
A PMP+ P P P PR + ++P+ S QEQ
Sbjct: 868 AKPMPKGSPTP-------PGPRPTAGQTVPTPQQSPKPQEQ 901
Score = 63.2 bits (152), Expect = 2e-09
Identities = 87/320 (27%), Positives = 127/320 (39%), Gaps = 78/320 (24%)
Query: 1076 GLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS-RAPSRTPGP---PSAQSSP--IDAQP 1129
G+G +P+ P P + PT G L +P ++P++ PGP P Q P I AQ
Sbjct: 396 GVGKTPAQQP--GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 1130 ATPL--------PQKDPAQPLEPKRPPPPRP---VAPPTRPA----PPQRP----PPPS- 1169
A P P K P+Q P +PPP +P PP +P P Q+P PPP
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ 513
Query: 1170 -GARSPAPTRKEFGGIGAPPS--PGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPG 1226
G P+P + G PPS PG A+ + P + + + ++P Q G
Sbjct: 514 PGPAKPSPQQP---GSTKPPSQQPGSAKPSAQQPSPAKPSAQQS---TKPVSQTG----- 562
Query: 1227 PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLK----- 1281
+G PT+ P A P S P++ T++ +PE
Sbjct: 563 -SGKPLQPPTVSPSA---KQPPSQG-------LPKTICPLCNTTELLLHVPEKANFNTCT 611
Query: 1282 -------PQAAFPPQSSLPPPAQ------RLQEPLVPVAAPMPQSGPQPNLETPPQPPPR 1328
F P L + +++ L AP+P S PQP L+T P
Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP-SSPQPKLKTAPV---- 666
Query: 1329 SRSSHSLPSEASSQPQQEQP 1348
++ S S++S QPQQ P
Sbjct: 667 --TTTSAVSKSSPQPQQTSP 684
Score = 57.0 bits (136), Expect = 1e-07
Identities = 71/289 (24%), Positives = 98/289 (33%), Gaps = 25/289 (8%)
Query: 1067 QHLQPSSSSGLGTSPSSSPRT--SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
Q P +S T P+ P P + P GP P +P A + P S + P
Sbjct: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGI 1184
PA P PQ QP K P A P+ P P PS +S P + G
Sbjct: 512 QQPGPAKPSPQ----QPGSTKPPSQQPGSAKPSAQQP--SPAKPSAQQSTKPVSQT--GS 563
Query: 1185 GAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYST---ARPTIPPRA 1241
G P P + P S G + I + + L P A ++T + T+
Sbjct: 564 GKPLQPPTVSPSAKQPPSQGLPK--TICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
G P H L Q K + G P P PQ A
Sbjct: 622 GF--NPNPHLTEVKEWLCLNCQMK---RALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSS 676
Query: 1302 PLVPVAAPMPQSGPQPNLETPPQP--PP---RSRSSHSLPSEASSQPQQ 1345
P +P + P+ +L P+P PP + + H PS + QP +
Sbjct: 677 PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725
Score = 57.0 bits (136), Expect = 1e-07
Identities = 69/287 (24%), Positives = 100/287 (34%), Gaps = 19/287 (6%)
Query: 1065 LPQHLQPSSSSGLGTSPSSSPRTSPCQ---SPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1121
+P QP + T+ S+ ++SP SP P L S+AP PP +
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL----SKAPEPKKPPPLVK 708
Query: 1122 SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEF 1181
+ P+ Q A L K PP P P + P P + PT
Sbjct: 709 QPTLHGSPSAKAKQPPEADSLS-KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767
Query: 1182 GGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY-STARPTIPPR 1240
A P + ++++ TT ++PS G + + S A P
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 1241 AGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQ 1300
+ +IS P + S G+ + K E K T + KP A P+ S PP R
Sbjct: 828 SKIISHP-GPSSESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMPKGSPTPPGPR-- 882
Query: 1301 EPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQ 1347
P P PQ P+P Q S + S+ SQP Q
Sbjct: 883 -PTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITDAPKSQPTTPQ 924
Score = 51.6 bits (122), Expect = 5e-06
Identities = 76/288 (26%), Positives = 105/288 (36%), Gaps = 41/288 (14%)
Query: 1059 AEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG-- 1116
++ EE L+ S+ + P + + SP S I S I S + G
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 1117 ---PPSAQSSPIDAQPATPLPQKDPAQPLEPK---RPPPPRPVAPPTRPAPPQRPPPPSG 1170
P + P AQ T + K A+P+ PK PP PRP A T P P Q P P
Sbjct: 845 QVDPVQKKEEPKKAQ--TKMSPKPDAKPM-PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901
Query: 1171 ARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
+R G I +APKS TT ++ + L G G + +
Sbjct: 902 SRR---FSLNLGSI------------TDAPKSQPTTPQETV-------TGKLFGFGASIF 939
Query: 1231 STARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQS 1290
S A I QS A + SQ TS+ ST P P + P +
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPP-APAKSIPVKK 998
Query: 1291 SLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE 1338
PA EP A + ++ ET +PPP + S SL +E
Sbjct: 999 ETKAPAAEKLEPKAEQAPTVKRT------ETEKKPPP-IKDSKSLTAE 1039
Score = 50.8 bits (120), Expect = 9e-06
Identities = 61/254 (24%), Positives = 87/254 (34%), Gaps = 30/254 (11%)
Query: 1108 SRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1167
S+ PS G PS S P +P D + P PPPP P PP P PP PPP
Sbjct: 2374 SQLPS---GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP 2430
Query: 1168 PSGARSPAPTRKEFGG----IGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLA 1223
S + P +K P V E A I + P P
Sbjct: 2431 TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKP 2490
Query: 1224 GPGPAGY------STARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSE-----TSKG 1272
P+G ++P I P+ + P + + + P S TS +
Sbjct: 2491 SSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSA 2550
Query: 1273 STFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSS 1332
LP P P + +SS P ++ L E V + P + P P S +S
Sbjct: 2551 DYKLPSPTSPLSPHSNKSS-PRFSKSLTETYVVITLP-----------SEPGTPTDSSAS 2598
Query: 1333 HSLPSEASSQPQQE 1346
++ S P ++
Sbjct: 2599 QAITSWPLGSPSKD 2612
Score = 39.7 bits (91), Expect = 0.020
Identities = 68/326 (20%), Positives = 113/326 (34%), Gaps = 67/326 (20%)
Query: 1071 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPA 1130
P S SG G +P +P Q PT S+GP P +AP P A+S P+ +
Sbjct: 954 PHSQSGPGAPMKQAP--APSQPPT-SQGP----PKSTGQAP-----PAPAKSIPVKKETK 1001
Query: 1131 TPLPQK-DPAQPLEP--------KRPPPPRP----VAPPTRPAPP---QRPPPPSGARSP 1174
P +K +P P K+PPP + A P + P ++ P P
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
Query: 1175 APTRKEFGGIGAP-------------------PSPGVARREMEAPKSPGTTRK-----DN 1210
T G P P+P + + + T R +
Sbjct: 1062 CKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD 1121
Query: 1211 IGRSQPSPQAGLAGPGPAGY--STARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSE 1268
I + P+P A P P S+ + +PP+ ++ + + A ++ E +T
Sbjct: 1122 IRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS 1181
Query: 1269 TSKGSTFL-------PEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLET 1321
K + L+ A Q P P ++ L+P + +P LE
Sbjct: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEK---KLIPEEEKIRSEEKKPLLE- 1237
Query: 1322 PPQPPPRSRSSHSLPSEASSQPQQEQ 1347
+ P LP +S P++++
Sbjct: 1238 --EKKPTPEDKKLLPEAKTSAPEEQK 1261
Score = 38.1 bits (87), Expect = 0.058
Identities = 60/234 (25%), Positives = 82/234 (35%), Gaps = 40/234 (17%)
Query: 1140 QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEA 1199
Q + K P + P P Q+ PP + P R G P S + E
Sbjct: 193 QKVVQKEQGKPEGIIKP----PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIK 248
Query: 1200 PKSPGTTR--------------KDNIGRSQPSPQAGLA------GPGPAGYSTARPTI-P 1238
+ PGT + K + R PQ A P+ S ++P I
Sbjct: 249 SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308
Query: 1239 PRAGVISAPQ-SHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ 1297
P G A Q H ++ G P +Q S +K P +KP P + PPAQ
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQ--PSGLTKPLAQQPGTVKPPV--QPPGTTKPPAQ 364
Query: 1298 RLQEPLVPVAAPMPQSGPQ-PNLETP-----PQPPPRSRSSHSLPSEASSQPQQ 1345
PL P P Q+G + P+ E P QPP ++ P A QQ
Sbjct: 365 ----PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ 414
Score = 37.0 bits (84), Expect = 0.13
Identities = 48/219 (21%), Positives = 71/219 (32%), Gaps = 31/219 (14%)
Query: 1132 PLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPG 1191
P Q+ P +P+ ++ P P+ P P P T K G P
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD 268
Query: 1192 VARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHA 1251
A+ ++ S T++ +I R + S + L P P PP + H
Sbjct: 269 HAKLPLQRDASRPQTKQADIVRGE-SVKPSLPSPSKPPIQQPTPGKPP-----AQQPGHE 322
Query: 1252 RASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMP 1311
++ G P +Q S +K P +KP P + PPAQ L
Sbjct: 323 KSQPGPAKPPAQP--SGLTKPLAQQPGTVKPPVQ--PPGTTKPPAQPLG----------- 367
Query: 1312 QSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1350
P +PP + S SE QP G
Sbjct: 368 ----------PAKPPAQQTGSEKPSSEQPGPKALAQPPG 396
Score = 33.5 bits (75), Expect = 1.4
Identities = 33/108 (30%), Positives = 41/108 (37%), Gaps = 17/108 (15%)
Query: 1239 PRAGVISAPQSHARASA--------GRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQS 1290
P + VI+ P ++ G+ P SQ + S S P KP+ F S
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSL----PAKPRPFFR-SS 2397
Query: 1291 SLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE 1338
SL AQ P P P P P P PP PPP S LP +
Sbjct: 2398 SLDISAQPPPPPPPPPPPPPPPPPPPP----PPLPPPTSPKPTILPKK 2441
Score = 32.3 bits (72), Expect = 3.2
Identities = 46/167 (27%), Positives = 62/167 (37%), Gaps = 19/167 (11%)
Query: 1167 PPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPG 1226
PP + P P E G + + PKSP SP + L+ PG
Sbjct: 3586 PPKDKKRPTPL--EIGYSSHLRADSTVQLAPSPPKSPKVLY---------SPISPLS-PG 3633
Query: 1227 PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF 1286
A S P P IS PQ ++ P S KT++ + S P+PL P A
Sbjct: 3634 KALESAFVPYEKPLPDDIS-PQKVLHPDMAKVPPASP-KTAKMMQRSMSDPKPLSPTA-- 3689
Query: 1287 PPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE-TPPQPPPRSRSS 1332
S P Q + + M SG Q ++ T P PPP S+
Sbjct: 3690 --DESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEIST 3734
Score = 30.8 bits (68), Expect = 9.2
Identities = 50/226 (22%), Positives = 81/226 (35%), Gaps = 47/226 (20%)
Query: 1162 PQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPS---- 1217
P+ PP+ A SP+ RK+ PP ++ P PG + + +S+ +
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPP------KQSGRPPDPGRPAQPGLSKSRTTDTFR 120
Query: 1218 PQAGLAGPGPAGY----------------STARPTIPPRAGVISAPQSHA-RASAGRLTP 1260
+ L G P+ S+ P +SA S + + L
Sbjct: 121 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
Query: 1261 ESQSKTSETSKGSTFL-PEPLKPQAAFPP--QSSLPPPAQRLQ----EPLVPVAAPMPQS 1313
+S++ ET+K + E KP+ P Q P P + Q +PL P S
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240
Query: 1314 GPQPN------------LETPPQPPPRSRSSHSLPSEASSQPQQEQ 1347
QP ++ P Q P + L +A S+PQ +Q
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDA-SRPQTKQ 285
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 88.2 bits (217), Expect = 5e-17
Identities = 83/273 (30%), Positives = 111/273 (40%), Gaps = 39/273 (14%)
Query: 1097 EGPVPSLPIRPSRAPSR--TPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRP------- 1147
E PSLP PS+ P + TPG P AQ + + P P K PAQP +P
Sbjct: 292 ESVKPSLP-SPSKPPIQQPTPGKPPAQQP--GHEKSQPGPAKPPAQPSGLTKPLAQQPGT 348
Query: 1148 -----PPPRPVAPPTRPAPPQRPP-PPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPK 1201
PP PP +P P +PP +G+ P+ + + PP G + P
Sbjct: 349 VKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408
Query: 1202 SPGTTRKDNIGRSQP-SPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTP 1260
P T +G +P + Q GL P A T P P G I A Q A G+ +
Sbjct: 409 KPPT---QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ----AGPGKTSA 461
Query: 1261 ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP--PPAQRLQEPLVPVAAPMPQSGPQPN 1318
+ T S+ LP P KP PPQ P PP Q+ P P + P P
Sbjct: 462 QQTGPTKPPSQ----LPGPAKP----PPQQPGPAKPPPQQPGSAKPPSQQP-GSTKPPPQ 512
Query: 1319 LETPPQPPPRSRSSHSLPSE--ASSQPQQEQPS 1349
P +P P+ S PS+ S++P +QPS
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS 545
Score = 85.9 bits (211), Expect = 2e-16
Identities = 89/297 (29%), Positives = 118/297 (39%), Gaps = 41/297 (13%)
Query: 1066 PQHLQPSSSSGLGTSPS-SSPRTSPCQSPTISEGPVPSLPIRPSR-APSRTPGPPSAQSS 1123
PQ Q G PS SP P Q PT + P S+ P++ P PS +
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 1124 PIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP-SGARSPAPTRKEFG 1182
P+ QP T P P QP P PP +P P +PP +G+ P+ +
Sbjct: 341 PLAQQPGTVKP---PVQP--------PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPK 389
Query: 1183 GIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQP-SPQAGLAGPGPAGYSTARPTIPPRA 1241
+ PP G + P P T + +G +P + Q GL P A T P P
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQ---VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGP 446
Query: 1242 GVISAPQSHARASAGRLT----PESQ----SKTSETSKGSTFLPEPLKPQAAFPPQ---- 1289
G I A Q+ ++ + T P SQ +K G P P +P +A PP
Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA-KPPPQQPGSAKPPSQQPG 505
Query: 1290 SSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPP-QPPPRSRSSHSLPSEASSQPQQ 1345
S+ PPP Q+P A P PQ QP PP Q P ++ S PS A QQ
Sbjct: 506 STKPPP----QQP--GPAKPSPQ---QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ 553
Score = 64.3 bits (155), Expect = 8e-10
Identities = 77/281 (27%), Positives = 107/281 (38%), Gaps = 63/281 (22%)
Query: 1099 PVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKD--PAQPL----EPKRPPP--- 1149
PVPS P + T ++SSP QP P+KD P Q L EPK+PPP
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSP---QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVK 708
Query: 1150 ---------PRPVAPP-----TRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARR 1195
+ PP ++PAPP+ P PS + AP + P P + +
Sbjct: 709 QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPS-EQDKAPVADD-----KPKQPKMVKP 762
Query: 1196 EMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP--TIPPRAGVISAPQSHA-- 1251
+ S T K +I S+ QA P +A+P + PP +S S A
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 1252 -RASAGRLT----PESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPV 1306
AS ++ P S+SK + EP K Q P+ P
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK---------------PD 867
Query: 1307 AAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQ 1347
A PMP+ P P P PR + ++P+ S QEQ
Sbjct: 868 AKPMPKGSPTP-------PGPRPTAGQTVPTPQQSPKPQEQ 901
Score = 63.2 bits (152), Expect = 2e-09
Identities = 87/320 (27%), Positives = 127/320 (39%), Gaps = 78/320 (24%)
Query: 1076 GLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPS-RAPSRTPGP---PSAQSSP--IDAQP 1129
G+G +P+ P P + PT G L +P ++P++ PGP P Q P I AQ
Sbjct: 396 GVGKTPAQQP--GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 1130 ATPL--------PQKDPAQPLEPKRPPPPRP---VAPPTRPA----PPQRP----PPPS- 1169
A P P K P+Q P +PPP +P PP +P P Q+P PPP
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ 513
Query: 1170 -GARSPAPTRKEFGGIGAPPS--PGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPG 1226
G P+P + G PPS PG A+ + P + + + ++P Q G
Sbjct: 514 PGPAKPSPQQP---GSTKPPSQQPGSAKPSAQQPSPAKPSAQQS---TKPVSQTG----- 562
Query: 1227 PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLK----- 1281
+G PT+ P A P S P++ T++ +PE
Sbjct: 563 -SGKPLQPPTVSPSA---KQPPSQG-------LPKTICPLCNTTELLLHVPEKANFNTCT 611
Query: 1282 -------PQAAFPPQSSLPPPAQ------RLQEPLVPVAAPMPQSGPQPNLETPPQPPPR 1328
F P L + +++ L AP+P S PQP L+T P
Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP-SSPQPKLKTAPV---- 666
Query: 1329 SRSSHSLPSEASSQPQQEQP 1348
++ S S++S QPQQ P
Sbjct: 667 --TTTSAVSKSSPQPQQTSP 684
Score = 57.0 bits (136), Expect = 1e-07
Identities = 71/289 (24%), Positives = 98/289 (33%), Gaps = 25/289 (8%)
Query: 1067 QHLQPSSSSGLGTSPSSSPRT--SPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSP 1124
Q P +S T P+ P P + P GP P +P A + P S + P
Sbjct: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511
Query: 1125 IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGI 1184
PA P PQ QP K P A P+ P P PS +S P + G
Sbjct: 512 QQPGPAKPSPQ----QPGSTKPPSQQPGSAKPSAQQP--SPAKPSAQQSTKPVSQT--GS 563
Query: 1185 GAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYST---ARPTIPPRA 1241
G P P + P S G + I + + L P A ++T + T+
Sbjct: 564 GKPLQPPTVSPSAKQPPSQGLPK--TICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
Query: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
G P H L Q K + G P P PQ A
Sbjct: 622 GF--NPNPHLTEVKEWLCLNCQMK---RALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSS 676
Query: 1302 PLVPVAAPMPQSGPQPNLETPPQP--PP---RSRSSHSLPSEASSQPQQ 1345
P +P + P+ +L P+P PP + + H PS + QP +
Sbjct: 677 PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725
Score = 57.0 bits (136), Expect = 1e-07
Identities = 69/287 (24%), Positives = 100/287 (34%), Gaps = 19/287 (6%)
Query: 1065 LPQHLQPSSSSGLGTSPSSSPRTSPCQ---SPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1121
+P QP + T+ S+ ++SP SP P L S+AP PP +
Sbjct: 653 VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL----SKAPEPKKPPPLVK 708
Query: 1122 SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEF 1181
+ P+ Q A L K PP P P + P P + PT
Sbjct: 709 QPTLHGSPSAKAKQPPEADSLS-KPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767
Query: 1182 GGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY-STARPTIPPR 1240
A P + ++++ TT ++PS G + + S A P
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 1241 AGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQ 1300
+ +IS P + S G+ + K E K T + KP A P+ S PP R
Sbjct: 828 SKIISHP-GPSSESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMPKGSPTPPGPR-- 882
Query: 1301 EPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQ 1347
P P PQ P+P Q S + S+ SQP Q
Sbjct: 883 -PTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITDAPKSQPTTPQ 924
Score = 51.6 bits (122), Expect = 5e-06
Identities = 76/288 (26%), Positives = 105/288 (36%), Gaps = 41/288 (14%)
Query: 1059 AEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPG-- 1116
++ EE L+ S+ + P + + SP S I S I S + G
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 1117 ---PPSAQSSPIDAQPATPLPQKDPAQPLEPK---RPPPPRPVAPPTRPAPPQRPPPPSG 1170
P + P AQ T + K A+P+ PK PP PRP A T P P Q P P
Sbjct: 845 QVDPVQKKEEPKKAQ--TKMSPKPDAKPM-PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901
Query: 1171 ARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGY 1230
+R G I +APKS TT ++ + L G G + +
Sbjct: 902 SRR---FSLNLGSI------------TDAPKSQPTTPQETV-------TGKLFGFGASIF 939
Query: 1231 STARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQS 1290
S A I QS A + SQ TS+ ST P P + P +
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPP-APAKSIPVKK 998
Query: 1291 SLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE 1338
PA EP A + ++ ET +PPP + S SL +E
Sbjct: 999 ETKAPAAEKLEPKAEQAPTVKRT------ETEKKPPP-IKDSKSLTAE 1039
Score = 50.8 bits (120), Expect = 9e-06
Identities = 61/254 (24%), Positives = 87/254 (34%), Gaps = 30/254 (11%)
Query: 1108 SRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPP 1167
S+ PS G PS S P +P D + P PPPP P PP P PP PPP
Sbjct: 2374 SQLPS---GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP 2430
Query: 1168 PSGARSPAPTRKEFGG----IGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLA 1223
S + P +K P V E A I + P P
Sbjct: 2431 TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKP 2490
Query: 1224 GPGPAGY------STARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSE-----TSKG 1272
P+G ++P I P+ + P + + + P S TS +
Sbjct: 2491 SSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSA 2550
Query: 1273 STFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSS 1332
LP P P + +SS P ++ L E V + P + P P S +S
Sbjct: 2551 DYKLPSPTSPLSPHSNKSS-PRFSKSLTETYVVITLP-----------SEPGTPTDSSAS 2598
Query: 1333 HSLPSEASSQPQQE 1346
++ S P ++
Sbjct: 2599 QAITSWPLGSPSKD 2612
Score = 39.7 bits (91), Expect = 0.020
Identities = 68/326 (20%), Positives = 113/326 (34%), Gaps = 67/326 (20%)
Query: 1071 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPA 1130
P S SG G +P +P Q PT S+GP P +AP P A+S P+ +
Sbjct: 954 PHSQSGPGAPMKQAP--APSQPPT-SQGP----PKSTGQAP-----PAPAKSIPVKKETK 1001
Query: 1131 TPLPQK-DPAQPLEP--------KRPPPPRP----VAPPTRPAPP---QRPPPPSGARSP 1174
P +K +P P K+PPP + A P + P ++ P P
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
Query: 1175 APTRKEFGGIGAP-------------------PSPGVARREMEAPKSPGTTRK-----DN 1210
T G P P+P + + + T R +
Sbjct: 1062 CKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD 1121
Query: 1211 IGRSQPSPQAGLAGPGPAGY--STARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSE 1268
I + P+P A P P S+ + +PP+ ++ + + A ++ E +T
Sbjct: 1122 IRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS 1181
Query: 1269 TSKGSTFL-------PEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLET 1321
K + L+ A Q P P ++ L+P + +P LE
Sbjct: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEK---KLIPEEEKIRSEEKKPLLE- 1237
Query: 1322 PPQPPPRSRSSHSLPSEASSQPQQEQ 1347
+ P LP +S P++++
Sbjct: 1238 --EKKPTPEDKKLLPEAKTSAPEEQK 1261
Score = 38.1 bits (87), Expect = 0.058
Identities = 60/234 (25%), Positives = 82/234 (35%), Gaps = 40/234 (17%)
Query: 1140 QPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEA 1199
Q + K P + P P Q+ PP + P R G P S + E
Sbjct: 193 QKVVQKEQGKPEGIIKP----PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIK 248
Query: 1200 PKSPGTTR--------------KDNIGRSQPSPQAGLA------GPGPAGYSTARPTI-P 1238
+ PGT + K + R PQ A P+ S ++P I
Sbjct: 249 SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308
Query: 1239 PRAGVISAPQ-SHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ 1297
P G A Q H ++ G P +Q S +K P +KP P + PPAQ
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQ--PSGLTKPLAQQPGTVKPPV--QPPGTTKPPAQ 364
Query: 1298 RLQEPLVPVAAPMPQSGPQ-PNLETP-----PQPPPRSRSSHSLPSEASSQPQQ 1345
PL P P Q+G + P+ E P QPP ++ P A QQ
Sbjct: 365 ----PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ 414
Score = 37.0 bits (84), Expect = 0.13
Identities = 48/219 (21%), Positives = 71/219 (32%), Gaps = 31/219 (14%)
Query: 1132 PLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPG 1191
P Q+ P +P+ ++ P P+ P P P T K G P
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD 268
Query: 1192 VARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHA 1251
A+ ++ S T++ +I R + S + L P P PP + H
Sbjct: 269 HAKLPLQRDASRPQTKQADIVRGE-SVKPSLPSPSKPPIQQPTPGKPP-----AQQPGHE 322
Query: 1252 RASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMP 1311
++ G P +Q S +K P +KP P + PPAQ L
Sbjct: 323 KSQPGPAKPPAQP--SGLTKPLAQQPGTVKPPVQ--PPGTTKPPAQPLG----------- 367
Query: 1312 QSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1350
P +PP + S SE QP G
Sbjct: 368 ----------PAKPPAQQTGSEKPSSEQPGPKALAQPPG 396
Score = 33.5 bits (75), Expect = 1.4
Identities = 33/108 (30%), Positives = 41/108 (37%), Gaps = 17/108 (15%)
Query: 1239 PRAGVISAPQSHARASA--------GRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQS 1290
P + VI+ P ++ G+ P SQ + S S P KP+ F S
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSL----PAKPRPFFR-SS 2397
Query: 1291 SLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE 1338
SL AQ P P P P P P PP PPP S LP +
Sbjct: 2398 SLDISAQPPPPPPPPPPPPPPPPPPPP----PPLPPPTSPKPTILPKK 2441
Score = 32.3 bits (72), Expect = 3.2
Identities = 46/167 (27%), Positives = 62/167 (37%), Gaps = 19/167 (11%)
Query: 1167 PPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPG 1226
PP + P P E G + + PKSP SP + L+ PG
Sbjct: 3586 PPKDKKRPTPL--EIGYSSHLRADSTVQLAPSPPKSPKVLY---------SPISPLS-PG 3633
Query: 1227 PAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAF 1286
A S P P IS PQ ++ P S KT++ + S P+PL P A
Sbjct: 3634 KALESAFVPYEKPLPDDIS-PQKVLHPDMAKVPPASP-KTAKMMQRSMSDPKPLSPTA-- 3689
Query: 1287 PPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLE-TPPQPPPRSRSS 1332
S P Q + + M SG Q ++ T P PPP S+
Sbjct: 3690 --DESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEIST 3734
Score = 30.8 bits (68), Expect = 9.2
Identities = 50/226 (22%), Positives = 81/226 (35%), Gaps = 47/226 (20%)
Query: 1162 PQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPS---- 1217
P+ PP+ A SP+ RK+ PP ++ P PG + + +S+ +
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPP------KQSGRPPDPGRPAQPGLSKSRTTDTFR 120
Query: 1218 PQAGLAGPGPAGY----------------STARPTIPPRAGVISAPQSHA-RASAGRLTP 1260
+ L G P+ S+ P +SA S + + L
Sbjct: 121 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
Query: 1261 ESQSKTSETSKGSTFL-PEPLKPQAAFPP--QSSLPPPAQRLQ----EPLVPVAAPMPQS 1313
+S++ ET+K + E KP+ P Q P P + Q +PL P S
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240
Query: 1314 GPQPN------------LETPPQPPPRSRSSHSLPSEASSQPQQEQ 1347
QP ++ P Q P + L +A S+PQ +Q
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDA-SRPQTKQ 285
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,895,485
Number of Sequences: 37866
Number of extensions: 3520782
Number of successful extensions: 74606
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 851
Number of HSP's successfully gapped in prelim test: 2478
Number of HSP's that attempted gapping in prelim test: 22759
Number of HSP's gapped (non-prelim): 21374
length of query: 1350
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1236
effective length of database: 13,930,794
effective search space: 17218461384
effective search space used: 17218461384
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.