Search of human proteins with 236462242

Search of human proteins with 236462242

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|236462242 potassium voltage-gated channel, KQT-like
subfamily, member 5 isoform 5 [Homo sapiens]
         (822 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|236462242 potassium voltage-gated channel, KQT-like subfamily...  1627   0.0  
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,...   837   0.0  
gi|236462079 potassium voltage-gated channel, KQT-like subfamily...   837   0.0  
gi|236461942 potassium voltage-gated channel, KQT-like subfamily...   821   0.0  
gi|236461719 potassium voltage-gated channel, KQT-like subfamily...   819   0.0  
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i...   510   e-144
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i...   510   e-144
gi|26051262 potassium voltage-gated channel KQT-like protein 2 i...   474   e-133
gi|26051264 potassium voltage-gated channel KQT-like protein 2 i...   474   e-133
gi|26051266 potassium voltage-gated channel KQT-like protein 2 i...   474   e-133
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i...   473   e-133
gi|26051260 potassium voltage-gated channel KQT-like protein 2 i...   472   e-133
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H...   442   e-124
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,...   352   1e-96
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,...   323   4e-88
gi|88758565 potassium voltage-gated channel, shaker-related subf...    90   7e-18
gi|27436974 potassium voltage-gated channel, Shab-related subfam...    88   3e-17
gi|24497464 Shaw-related voltage-gated potassium channel protein...    87   5e-17
gi|4826784 potassium voltage-gated channel, Shab-related subfami...    87   6e-17
gi|4504817 potassium voltage-gated channel, shaker-related subfa...    87   6e-17
gi|88758576 Shaw-related voltage-gated potassium channel protein...    87   6e-17
gi|24497462 Shaw-related voltage-gated potassium channel protein...    87   6e-17
gi|119395748 potassium voltage-gated channel subfamily A member ...    86   1e-16
gi|21217561 Shaw-related voltage-gated potassium channel protein...    84   4e-16
gi|21217563 Shaw-related voltage-gated potassium channel protein...    84   4e-16
gi|24497458 Shaw-related voltage-gated potassium channel protein...    84   4e-16
gi|24497460 Shaw-related voltage-gated potassium channel protein...    82   2e-15
gi|4826782 potassium voltage-gated channel, shaker-related subfa...    81   3e-15
gi|9789987 potassium voltage-gated channel, Shal-related subfami...    80   6e-15
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]     80   6e-15

>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 5 [Homo sapiens]
          Length = 822

 Score = 1627 bits (4213), Expect = 0.0
 Identities = 822/822 (100%), Positives = 822/822 (100%)

Query: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60
           MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
Sbjct: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120
           LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
Sbjct: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120

Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180
           RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180

Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240
           SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240

Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300
           RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300

Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360
           ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360

Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSRIMKF 420
           KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSRIMKF
Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSRIMKF 420

Query: 421 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI 480
           HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI
Sbjct: 421 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI 480

Query: 481 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE 540
           TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE
Sbjct: 481 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE 540

Query: 541 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH 600
           CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH
Sbjct: 541 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH 600

Query: 601 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP 660
           SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP
Sbjct: 601 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP 660

Query: 661 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL 720
           AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL
Sbjct: 661 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL 720

Query: 721 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP 780
           SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP
Sbjct: 721 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP 780

Query: 781 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 822
           QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Sbjct: 781 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 822


>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 1 [Homo sapiens]
          Length = 932

 Score =  837 bits (2162), Expect = 0.0
 Identities = 420/432 (97%), Positives = 421/432 (97%), Gaps = 6/432 (1%)

Query: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60
           MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
Sbjct: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120
           LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
Sbjct: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120

Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180
           RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180

Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240
           SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240

Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300
           RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300

Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360
           ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360

Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSRIMKF 420
           KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASS     
Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSS---- 416

Query: 421 HVAKRKFKETLR 432
              K  FKE +R
Sbjct: 417 --QKLSFKERVR 426



 Score =  796 bits (2056), Expect = 0.0
 Identities = 407/407 (100%), Positives = 407/407 (100%)

Query: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 475
           RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK
Sbjct: 526 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 585

Query: 476 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 535
           SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ
Sbjct: 586 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 645

Query: 536 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 595
           IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL
Sbjct: 646 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 705

Query: 596 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 655
           SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET
Sbjct: 706 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 765

Query: 656 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 715
           LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD
Sbjct: 766 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 825

Query: 716 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 775
           LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT
Sbjct: 826 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 885

Query: 776 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 822
           FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Sbjct: 886 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 932


>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 4 [Homo sapiens]
          Length = 951

 Score =  837 bits (2161), Expect = 0.0
 Identities = 432/488 (88%), Positives = 441/488 (90%), Gaps = 11/488 (2%)

Query: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60
           MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
Sbjct: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120
           LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
Sbjct: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120

Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180
           RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180

Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240
           SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240

Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300
           RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300

Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360
           ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360

Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSRIMKF 420
           KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASS   KF
Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASS--SKF 418

Query: 421 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKS-REK 479
              K+K     R Y  +   ++ S        R++    R   I  +     D++S    
Sbjct: 419 CSNKQKL---FRMYTSRKQSQKLSFKE-----RVRMASPRGQSIKSRQASVGDRRSPSTD 470

Query: 480 ITAEHETT 487
           ITAE   T
Sbjct: 471 ITAEGSPT 478



 Score =  796 bits (2056), Expect = 0.0
 Identities = 407/407 (100%), Positives = 407/407 (100%)

Query: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 475
           RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK
Sbjct: 545 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 604

Query: 476 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 535
           SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ
Sbjct: 605 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 664

Query: 536 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 595
           IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL
Sbjct: 665 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 724

Query: 596 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 655
           SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET
Sbjct: 725 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 784

Query: 656 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 715
           LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD
Sbjct: 785 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 844

Query: 716 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 775
           LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT
Sbjct: 845 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 904

Query: 776 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 822
           FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Sbjct: 905 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 951


>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 3 [Homo sapiens]
          Length = 942

 Score =  821 bits (2120), Expect = 0.0
 Identities = 411/437 (94%), Positives = 420/437 (96%), Gaps = 6/437 (1%)

Query: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60
           MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
Sbjct: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120
           LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
Sbjct: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120

Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180
           RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180

Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240
           SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240

Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300
           RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300

Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360
           ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360

Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSRIMKF 420
           KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT K       ++ + 
Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSN-KQKLFRM 419

Query: 421 HVAKRK-----FKETLR 432
           + ++++     FKE +R
Sbjct: 420 YTSRKQSQKLSFKERVR 436



 Score =  796 bits (2056), Expect = 0.0
 Identities = 407/407 (100%), Positives = 407/407 (100%)

Query: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 475
           RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK
Sbjct: 536 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 595

Query: 476 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 535
           SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ
Sbjct: 596 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 655

Query: 536 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 595
           IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL
Sbjct: 656 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 715

Query: 596 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 655
           SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET
Sbjct: 716 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 775

Query: 656 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 715
           LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD
Sbjct: 776 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 835

Query: 716 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 775
           LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT
Sbjct: 836 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 895

Query: 776 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 822
           FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Sbjct: 896 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 942


>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 2 [Homo sapiens]
          Length = 923

 Score =  819 bits (2116), Expect = 0.0
 Identities = 406/409 (99%), Positives = 408/409 (99%)

Query: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60
           MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
Sbjct: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120
           LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
Sbjct: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120

Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180
           RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180

Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240
           SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240

Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300
           RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300

Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360
           ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360

Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKE 409
           KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT ++
Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNQK 409



 Score =  796 bits (2056), Expect = 0.0
 Identities = 407/407 (100%), Positives = 407/407 (100%)

Query: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 475
           RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK
Sbjct: 517 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 576

Query: 476 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 535
           SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ
Sbjct: 577 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 636

Query: 536 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 595
           IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL
Sbjct: 637 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 696

Query: 596 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 655
           SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET
Sbjct: 697 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 756

Query: 656 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 715
           LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD
Sbjct: 757 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 816

Query: 716 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 775
           LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT
Sbjct: 817 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 876

Query: 776 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 822
           FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Sbjct: 877 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 923


>gi|26638655 potassium voltage-gated channel KQT-like protein 4
           isoform b [Homo sapiens]
          Length = 641

 Score =  510 bits (1314), Expect = e-144
 Identities = 252/339 (74%), Positives = 281/339 (82%), Gaps = 24/339 (7%)

Query: 70  GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115
           GGGG  R         R+ LLG PL              S    +S   + +YRR+QN++
Sbjct: 37  GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87

Query: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175
           YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 88  YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147

Query: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235
           I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207

Query: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295
           FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267

Query: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355
           S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327

Query: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW 393
           EQHRQKHFEKRR PAANLIQ  WR Y+ D  ++   ATW
Sbjct: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATW 366



 Score =  182 bits (461), Expect = 1e-45
 Identities = 103/164 (62%), Positives = 126/164 (76%), Gaps = 8/164 (4%)

Query: 414 SSRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSD 473
           S RI+KF VAKRKFKETLRPYDVKDVIEQYSAGHLDML RIKSLQTRVDQI+G+G    D
Sbjct: 482 SIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGD 539

Query: 474 KKSRE---KITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALA 530
           +K+RE   K  ++ E  D++SM+GRVVKVEKQVQSIE KLD LL  Y + LR G+++  +
Sbjct: 540 RKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--S 597

Query: 531 LASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 574
           L + Q+P F+ + TSDY SPVD +D+S SAQ    +SRS S N+
Sbjct: 598 LGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLS-ISRSVSTNM 640


>gi|26638653 potassium voltage-gated channel KQT-like protein 4
           isoform a [Homo sapiens]
          Length = 695

 Score =  510 bits (1314), Expect = e-144
 Identities = 252/339 (74%), Positives = 281/339 (82%), Gaps = 24/339 (7%)

Query: 70  GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115
           GGGG  R         R+ LLG PL              S    +S   + +YRR+QN++
Sbjct: 37  GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87

Query: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175
           YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 88  YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147

Query: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235
           I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207

Query: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295
           FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267

Query: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355
           S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327

Query: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW 393
           EQHRQKHFEKRR PAANLIQ  WR Y+ D  ++   ATW
Sbjct: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATW 366



 Score =  182 bits (461), Expect = 1e-45
 Identities = 103/164 (62%), Positives = 126/164 (76%), Gaps = 8/164 (4%)

Query: 414 SSRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSD 473
           S RI+KF VAKRKFKETLRPYDVKDVIEQYSAGHLDML RIKSLQTRVDQI+G+G    D
Sbjct: 536 SIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGD 593

Query: 474 KKSRE---KITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALA 530
           +K+RE   K  ++ E  D++SM+GRVVKVEKQVQSIE KLD LL  Y + LR G+++  +
Sbjct: 594 RKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--S 651

Query: 531 LASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 574
           L + Q+P F+ + TSDY SPVD +D+S SAQ    +SRS S N+
Sbjct: 652 LGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLS-ISRSVSTNM 694


>gi|26051262 potassium voltage-gated channel KQT-like protein 2
           isoform b [Homo sapiens]
          Length = 854

 Score =  474 bits (1219), Expect = e-133
 Identities = 241/368 (65%), Positives = 282/368 (76%), Gaps = 17/368 (4%)

Query: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77

Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137

Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197

Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257

Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317

Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTKKEQ 410
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +     + + Q
Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377

Query: 411 GEASSRIM 418
              +SR++
Sbjct: 378 TYGASRLI 385



 Score =  138 bits (347), Expect = 2e-32
 Identities = 85/168 (50%), Positives = 106/168 (63%), Gaps = 8/168 (4%)

Query: 417 IMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKS 476
           +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQI+G+G   +D K 
Sbjct: 527 VMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITD-KD 585

Query: 477 REKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQI 536
           R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++IY Q  R G       A F  
Sbjct: 586 RTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGA 643

Query: 537 PPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTP 584
              E E    Y SP DS++        GC+ +   ++ S G +    P
Sbjct: 644 K--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQKNFSAP 686


>gi|26051264 potassium voltage-gated channel KQT-like protein 2
           isoform a [Homo sapiens]
          Length = 872

 Score =  474 bits (1219), Expect = e-133
 Identities = 241/368 (65%), Positives = 282/368 (76%), Gaps = 17/368 (4%)

Query: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77

Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137

Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197

Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257

Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317

Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTKKEQ 410
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +     + + Q
Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377

Query: 411 GEASSRIM 418
              +SR++
Sbjct: 378 TYGASRLI 385



 Score =  138 bits (347), Expect = 2e-32
 Identities = 85/168 (50%), Positives = 106/168 (63%), Gaps = 8/168 (4%)

Query: 417 IMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKS 476
           +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQI+G+G   +D K 
Sbjct: 545 VMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITD-KD 603

Query: 477 REKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQI 536
           R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++IY Q  R G       A F  
Sbjct: 604 RTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGA 661

Query: 537 PPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTP 584
              E E    Y SP DS++        GC+ +   ++ S G +    P
Sbjct: 662 K--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQKNFSAP 704


>gi|26051266 potassium voltage-gated channel KQT-like protein 2
           isoform d [Homo sapiens]
          Length = 841

 Score =  474 bits (1219), Expect = e-133
 Identities = 241/368 (65%), Positives = 282/368 (76%), Gaps = 17/368 (4%)

Query: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77

Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137

Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197

Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257

Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317

Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTKKEQ 410
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +     + + Q
Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377

Query: 411 GEASSRIM 418
              +SR++
Sbjct: 378 TYGASRLI 385



 Score =  138 bits (347), Expect = 2e-32
 Identities = 85/168 (50%), Positives = 106/168 (63%), Gaps = 8/168 (4%)

Query: 417 IMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKS 476
           +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQI+G+G   +D K 
Sbjct: 514 VMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITD-KD 572

Query: 477 REKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQI 536
           R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++IY Q  R G       A F  
Sbjct: 573 RTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGA 630

Query: 537 PPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTP 584
              E E    Y SP DS++        GC+ +   ++ S G +    P
Sbjct: 631 K--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQKNFSAP 673


>gi|26051268 potassium voltage-gated channel KQT-like protein 2
           isoform e [Homo sapiens]
          Length = 393

 Score =  473 bits (1216), Expect = e-133
 Identities = 240/370 (64%), Positives = 281/370 (75%), Gaps = 17/370 (4%)

Query: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77

Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137

Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197

Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257

Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317

Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTKKEQ 410
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +       + +
Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRYRRR 377

Query: 411 GEASSRIMKF 420
             A+ ++  F
Sbjct: 378 APATKQLFHF 387


>gi|26051260 potassium voltage-gated channel KQT-like protein 2
           isoform c [Homo sapiens]
          Length = 844

 Score =  472 bits (1214), Expect = e-133
 Identities = 238/344 (69%), Positives = 271/344 (78%), Gaps = 17/344 (4%)

Query: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77

Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137

Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197

Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257

Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317

Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWK 394
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+
Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQ 361



 Score =  138 bits (347), Expect = 2e-32
 Identities = 85/168 (50%), Positives = 106/168 (63%), Gaps = 8/168 (4%)

Query: 417 IMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKS 476
           +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQI+G+G   +D K 
Sbjct: 517 VMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITD-KD 575

Query: 477 REKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQI 536
           R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++IY Q  R G       A F  
Sbjct: 576 RTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGA 633

Query: 537 PPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTP 584
              E E    Y SP DS++        GC+ +   ++ S G +    P
Sbjct: 634 K--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQKNFSAP 676


>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
           sapiens]
          Length = 872

 Score =  442 bits (1138), Expect = e-124
 Identities = 244/427 (57%), Positives = 290/427 (67%), Gaps = 38/427 (8%)

Query: 7   GGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGR------VLLNSAAARGDGLLL 60
           GG +GG  G     G AA  AGG    +G ++ + G          L   A A  DG LL
Sbjct: 14  GGGDGGGGG-----GGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLL 68

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGK-PLSYTSSQSCRRNVKYRRVQNYLYNVL 119
           L         GGG     RR  QG  + LL K PLS       R N KYRR+Q  +Y+ L
Sbjct: 69  L--------EGGGRDEGQRRTPQG--IGLLAKTPLSRPVK---RNNAKYRRIQTLIYDAL 115

Query: 120 ERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRI 179
           ERPRGWA +YHA VFL+V GCLIL+V +T  E+  ++   LL+LE   I +FG EF +RI
Sbjct: 116 ERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRI 175

Query: 180 WSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQI 239
           W+AGCCCRY+GW+GRL+FARKP C++D  VLIAS+ VV+   QGN+ ATS LRSLRFLQI
Sbjct: 176 WAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS-LRSLRFLQI 234

Query: 240 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-------- 291
           LRM+RMDRRGGTWKLLGS + AHSKELITAWYIGFL LI SSFLVYLVEKD         
Sbjct: 235 LRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGE 294

Query: 292 --NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSG 349
              +EF TYADALWWG ITL TIGYGDKTP TW GRL++A F+L+G+SFFALPAGILGSG
Sbjct: 295 EMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSG 354

Query: 350 FALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVS-IATWKPHLKALHTCSPTKK 408
            ALKVQEQHRQKHFEKRR PAA LIQ  WR YA +   +  +ATW+   +++ +    +K
Sbjct: 355 LALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWR-FYESVVSFPFFRK 413

Query: 409 EQGEASS 415
           EQ EA+S
Sbjct: 414 EQLEAAS 420



 Score =  108 bits (269), Expect = 3e-23
 Identities = 61/127 (48%), Positives = 80/127 (62%), Gaps = 19/127 (14%)

Query: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 475
           RI++F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQTR+D I   G  ++ K 
Sbjct: 523 RILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKH 582

Query: 476 SR-----------------EKITAEHETT--DDLSMLGRVVKVEKQVQSIESKLDCLLDI 516
            +                 E   A   T+  +D SM+G+ VKVE+QVQ +  KLD L+D+
Sbjct: 583 KKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDM 642

Query: 517 YQQVLRK 523
           + Q + +
Sbjct: 643 HMQHMER 649


>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 1 [Homo sapiens]
          Length = 676

 Score =  352 bits (902), Expect = 1e-96
 Identities = 184/338 (54%), Positives = 238/338 (70%), Gaps = 13/338 (3%)

Query: 98  SSQSCRRNVKYR-RVQNYLYNVLERPRGW-AFIYHAFVFLLVFGCLILSVFSTIPEHTKL 155
           S  S RR V  R  VQ  +YN LERP GW  F+YH  VFL+V  CLI SV STI ++  L
Sbjct: 92  SIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAAL 151

Query: 156 ASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIA 215
           A+  L  +E V++V FG E+++R+WSAGC  +Y G  GRLRFARKP  +ID IV++AS+ 
Sbjct: 152 ATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMV 211

Query: 216 VVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFL 275
           V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVV+ H +ELIT  YIGFL
Sbjct: 212 VLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFL 271

Query: 276 VLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAG 330
            LIFSS+ VYL EKDA       EF +YADALWWG +T+TTIGYGDK P TW+G+ +++ 
Sbjct: 272 GLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASC 331

Query: 331 FALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI 390
           F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA+LIQ  WR YAA+    S 
Sbjct: 332 FSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSS- 390

Query: 391 ATWKPHLKAL---HT-CSPTKKEQGEASSRIMKFHVAK 424
            TWK +++     HT  SP+ K +     +  KF + K
Sbjct: 391 -TWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDK 427



 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 42/108 (38%), Positives = 70/108 (64%), Gaps = 10/108 (9%)

Query: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQ--ITSD 473
           R M++ VAK+KF++  +PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +GK    I+  
Sbjct: 518 RRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVS 577

Query: 474 KKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVL 521
           +KS+++           ++  R+ +VE +V  ++ +L  + D+  Q+L
Sbjct: 578 EKSKDR--------GSNTIGARLNRVEDKVTQLDQRLALITDMLHQLL 617


>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 2 [Homo sapiens]
          Length = 549

 Score =  323 bits (828), Expect = 4e-88
 Identities = 164/300 (54%), Positives = 216/300 (72%), Gaps = 11/300 (3%)

Query: 134 FLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQG 193
           FL+V  CLI SV STI ++  LA+  L  +E V++V FG E+++R+WSAGC  +Y G  G
Sbjct: 3   FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62

Query: 194 RLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWK 253
           RLRFARKP  +ID IV++AS+ V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 63  RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122

Query: 254 LLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTIT 308
           LLGSVV+ H +ELIT  YIGFL LIFSS+ VYL EKDA       EF +YADALWWG +T
Sbjct: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182

Query: 309 LTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368
           +TTIGYGDK P TW+G+ +++ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++  
Sbjct: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242

Query: 369 PAANLIQCVWRSYAADEKSVSIATWKPHLKAL---HT-CSPTKKEQGEASSRIMKFHVAK 424
            AA+LIQ  WR YAA+    S  TWK +++     HT  SP+ K +     +  KF + K
Sbjct: 243 AAASLIQTAWRCYAAENPDSS--TWKIYIRKAPRSHTLLSPSPKPKKSVVVKKKKFKLDK 300



 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 42/108 (38%), Positives = 70/108 (64%), Gaps = 10/108 (9%)

Query: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQ--ITSD 473
           R M++ VAK+KF++  +PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +GK    I+  
Sbjct: 391 RRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVS 450

Query: 474 KKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVL 521
           +KS+++           ++  R+ +VE +V  ++ +L  + D+  Q+L
Sbjct: 451 EKSKDR--------GSNTIGARLNRVEDKVTQLDQRLALITDMLHQLL 490


>gi|88758565 potassium voltage-gated channel, shaker-related
           subfamily, member 3 [Homo sapiens]
          Length = 575

 Score = 90.1 bits (222), Expect = 7e-18
 Identities = 53/201 (26%), Positives = 103/201 (51%), Gaps = 16/201 (7%)

Query: 157 SSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIA---S 213
           S    ++E + I+ F  E ++R ++            +  F+R    +ID + +I    +
Sbjct: 292 SDPFFVVETLCIIWFSFELLVRFFAC---------PSKATFSRNIMNLIDIVAIIPYFIT 342

Query: 214 IAVVSAKTQGN---IFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITA 269
           +    A+ QGN     + + LR +R +++ R+ ++ R     ++LG  + A  +EL +  
Sbjct: 343 LGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 402

Query: 270 WYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSA 329
           +++   V++FSS + +    D    FS+  DA WW  +T+TT+GYGD  P+T  G+++ +
Sbjct: 403 FFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGS 462

Query: 330 GFALLGISFFALPAGILGSGF 350
             A+ G+   ALP  ++ S F
Sbjct: 463 LCAIAGVLTIALPVPVIVSNF 483


>gi|27436974 potassium voltage-gated channel, Shab-related
           subfamily, member 2 [Homo sapiens]
          Length = 911

 Score = 88.2 bits (217), Expect = 3e-17
 Identities = 71/270 (26%), Positives = 135/270 (50%), Gaps = 28/270 (10%)

Query: 115 LYNVLERPRGWA---FIYHAFVFLLVFGCLILSVFSTIPEHTKLA-------SSCLLILE 164
           L+++LE+P        +    +  +V   + LS+ +T+PE  +         +  L  +E
Sbjct: 179 LWDLLEKPNSSVAAKILAIVSILFIVLSTIALSL-NTLPELQETDEFGQLNDNRQLAHVE 237

Query: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIAS-IAVVSAKTQG 223
            V I  F +E+++R  S+           + +F + P  VID + ++   + +   ++  
Sbjct: 238 AVCIAWFTMEYLLRFLSS---------PNKWKFFKGPLNVIDLLAILPYYVTIFLTESNK 288

Query: 224 NIFATSALRSL----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLI 278
           ++     +R +    R ++ILR++++ R     + LG  +     EL +   ++   ++I
Sbjct: 289 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 348

Query: 279 FSSFLVYLVEKDANK-EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGIS 337
           FSS LV+  EKD +  +F++   + WW TIT+TT+GYGD  P T LG+++     + G+ 
Sbjct: 349 FSS-LVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL 407

Query: 338 FFALPAGILGSGFALKVQEQHRQKHFEKRR 367
             ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 408 VIALPIPIIVNNFSEFYKEQKRQEKAIKRR 437


>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
           isoform b [Homo sapiens]
          Length = 582

 Score = 87.4 bits (215), Expect = 5e-17
 Identities = 75/300 (25%), Positives = 133/300 (44%), Gaps = 43/300 (14%)

Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214
           L  +E V ++ F LEF++RI     CC        L F +    +ID + ++       +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAILPFYLEVGL 331

Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273
           + +S+K   ++     LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++ 
Sbjct: 332 SGLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389

Query: 274 FLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITLTTIGYGDKTPLTWLG 324
             VLIF++ + Y     A         + +F       WW  +T+TT+GYGD  P TW G
Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 449

Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQ-EQHRQKHFEKRRNPAANLIQCVWRSYAA 383
            L+ A  AL G+   A+P  ++ + F +       +QK  +KR+       Q     Y  
Sbjct: 450 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCK 509

Query: 384 DEKSVSIATWKPHLKALHTCSPTKKEQGEASSRIMKFHVAKRKFKETLRPYDVKDVIEQY 443
            E++       P        SP  +E+G          + +RK    +R ++ K +  Q+
Sbjct: 510 SEET------SPRDSTCSDTSPPAREEG----------MIERKRAGEIRGWEGKSLFPQW 553


>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
           member 1 [Homo sapiens]
          Length = 858

 Score = 87.0 bits (214), Expect = 6e-17
 Identities = 72/270 (26%), Positives = 134/270 (49%), Gaps = 28/270 (10%)

Query: 115 LYNVLERPRGWA---FIYHAFVFLLVFGCLILSVFSTIPEHTKLA-------SSCLLILE 164
           L+++LE+P        +    +  +V   + LS+ +T+PE   L        +  L  +E
Sbjct: 175 LWDLLEKPNSSVAAKILAIISIMFIVLSTIALSL-NTLPELQSLDEFGQSTDNPQLAHVE 233

Query: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIAS-IAVVSAKTQG 223
            V I  F +E+++R  S+      + W    +F + P   ID + ++   + +   ++  
Sbjct: 234 AVCIAWFTMEYLLRFLSSP-----KKW----KFFKGPLNAIDLLAILPYYVTIFLTESNK 284

Query: 224 NIFATSALRSL----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLI 278
           ++     +R +    R ++ILR++++ R     + LG  +     EL +   ++   ++I
Sbjct: 285 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 344

Query: 279 FSSFLVYLVEKDANK-EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGIS 337
           FSS LV+  EKD +  +F +   + WW TIT+TT+GYGD  P T LG+++     + G+ 
Sbjct: 345 FSS-LVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL 403

Query: 338 FFALPAGILGSGFALKVQEQHRQKHFEKRR 367
             ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 404 VIALPIPIIVNNFSEFYKEQKRQEKAIKRR 433


>gi|4504817 potassium voltage-gated channel, shaker-related
           subfamily, member 4 [Homo sapiens]
          Length = 653

 Score = 87.0 bits (214), Expect = 6e-17
 Identities = 59/226 (26%), Positives = 105/226 (46%), Gaps = 23/226 (10%)

Query: 162 ILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVS--- 218
           I+E V IV F  EF++R ++            +  F +    +ID + ++     +    
Sbjct: 373 IVETVCIVWFSFEFVVRCFAC---------PSQALFFKNIMNIIDIVSILPYFITLGTDL 423

Query: 219 AKTQGN-------IFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWY 271
           A+ QG          + + LR +R +++ R+ ++ R     ++LG  + A  +EL    +
Sbjct: 424 AQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIF 483

Query: 272 IGFLVLIFSSFLVYLVEKDA-NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAG 330
             F+ +I  S  VY  E D     F +  DA WW  +T+TT+GYGD  P+T  G+++ + 
Sbjct: 484 FLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSL 543

Query: 331 FALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQC 376
            A+ G+   ALP  ++ S F       HR+   E++     N + C
Sbjct: 544 CAIAGVLTIALPVPVIVSNFN---YFYHRETENEEQTQLTQNAVSC 586


>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
           isoform c [Homo sapiens]
          Length = 626

 Score = 87.0 bits (214), Expect = 6e-17
 Identities = 70/268 (26%), Positives = 121/268 (45%), Gaps = 33/268 (12%)

Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214
           L  +E V ++ F LEF++RI     CC        L F +    +ID + ++       +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAILPFYLEVGL 331

Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273
           + +S+K   ++     LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++ 
Sbjct: 332 SGLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389

Query: 274 FLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITLTTIGYGDKTPLTWLG 324
             VLIF++ + Y     A         + +F       WW  +T+TT+GYGD  P TW G
Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 449

Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQ-EQHRQKHFEKRRNPAANLIQCVWRSYAA 383
            L+ A  AL G+   A+P  ++ + F +       +QK  +KR+       Q     Y  
Sbjct: 450 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCK 509

Query: 384 DEKSVSIATWKPHLKALHTCSPTKKEQG 411
            E++       P        SP  +E+G
Sbjct: 510 SEET------SPRDSTCSDTSPPAREEG 531


>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
           isoform a [Homo sapiens]
          Length = 635

 Score = 87.0 bits (214), Expect = 6e-17
 Identities = 70/268 (26%), Positives = 121/268 (45%), Gaps = 33/268 (12%)

Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214
           L  +E V ++ F LEF++RI     CC        L F +    +ID + ++       +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAILPFYLEVGL 331

Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273
           + +S+K   ++     LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++ 
Sbjct: 332 SGLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389

Query: 274 FLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITLTTIGYGDKTPLTWLG 324
             VLIF++ + Y     A         + +F       WW  +T+TT+GYGD  P TW G
Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 449

Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQ-EQHRQKHFEKRRNPAANLIQCVWRSYAA 383
            L+ A  AL G+   A+P  ++ + F +       +QK  +KR+       Q     Y  
Sbjct: 450 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCK 509

Query: 384 DEKSVSIATWKPHLKALHTCSPTKKEQG 411
            E++       P        SP  +E+G
Sbjct: 510 SEET------SPRDSTCSDTSPPAREEG 531


>gi|119395748 potassium voltage-gated channel subfamily A member 1
           [Homo sapiens]
          Length = 495

 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 52/213 (24%), Positives = 108/213 (50%), Gaps = 18/213 (8%)

Query: 147 STIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVID 206
           +T+  ++ + +    I+E + I+ F  E ++R ++            +  F +     ID
Sbjct: 208 TTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFAC---------PSKTDFFKNIMNFID 258

Query: 207 TIVLIA---SIAVVSAKTQGNIFATSA-----LRSLRFLQILRMVRMDRRGGTWKLLGSV 258
            + +I    ++    A+ +GN     A     LR +R +++ R+ ++ R     ++LG  
Sbjct: 259 IVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQT 318

Query: 259 VYAHSKEL-ITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDK 317
           + A  +EL +  +++   V++FSS + +   ++A   FS+  DA WW  +++TT+GYGD 
Sbjct: 319 LKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDM 378

Query: 318 TPLTWLGRLLSAGFALLGISFFALPAGILGSGF 350
            P+T  G+++ +  A+ G+   ALP  ++ S F
Sbjct: 379 YPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNF 411


>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2a [Homo sapiens]
          Length = 613

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 69/283 (24%), Positives = 129/283 (45%), Gaps = 48/283 (16%)

Query: 107 KYRRVQNYLYNVLERP---RGWAFIYHAFVFLLVFG----CL---------------ILS 144
           ++RR+Q  ++ + E P   R   FI  A +F ++      CL               +++
Sbjct: 207 RWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVIN 266

Query: 145 VFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV 204
             S + ++       L  +E V +V F  EF++RI  +           +L F +    +
Sbjct: 267 GTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFS---------PNKLEFIKNLLNI 317

Query: 205 IDTIVLI-----ASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVV 259
           ID + ++       ++ +S+K   ++     LR +RF++ILR+ ++ R     ++LG  +
Sbjct: 318 IDFVAILPFYLEVGLSGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 375

Query: 260 YAHSKE-LITAWYIGFLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITL 309
            A + E L+   ++   VLIF++ + Y     A         + +F       WW  +T+
Sbjct: 376 RASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTM 435

Query: 310 TTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFAL 352
           TT+GYGD  P TW G L+ A  AL G+   A+P  ++ + F +
Sbjct: 436 TTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2b [Homo sapiens]
          Length = 638

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 69/283 (24%), Positives = 129/283 (45%), Gaps = 48/283 (16%)

Query: 107 KYRRVQNYLYNVLERP---RGWAFIYHAFVFLLVFG----CL---------------ILS 144
           ++RR+Q  ++ + E P   R   FI  A +F ++      CL               +++
Sbjct: 207 RWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVIN 266

Query: 145 VFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV 204
             S + ++       L  +E V +V F  EF++RI  +           +L F +    +
Sbjct: 267 GTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFS---------PNKLEFIKNLLNI 317

Query: 205 IDTIVLI-----ASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVV 259
           ID + ++       ++ +S+K   ++     LR +RF++ILR+ ++ R     ++LG  +
Sbjct: 318 IDFVAILPFYLEVGLSGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 375

Query: 260 YAHSKE-LITAWYIGFLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITL 309
            A + E L+   ++   VLIF++ + Y     A         + +F       WW  +T+
Sbjct: 376 RASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTM 435

Query: 310 TTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFAL 352
           TT+GYGD  P TW G L+ A  AL G+   A+P  ++ + F +
Sbjct: 436 TTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2c [Homo sapiens]
          Length = 558

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 69/283 (24%), Positives = 129/283 (45%), Gaps = 48/283 (16%)

Query: 107 KYRRVQNYLYNVLERP---RGWAFIYHAFVFLLVFG----CL---------------ILS 144
           ++RR+Q  ++ + E P   R   FI  A +F ++      CL               +++
Sbjct: 207 RWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVIN 266

Query: 145 VFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV 204
             S + ++       L  +E V +V F  EF++RI  +           +L F +    +
Sbjct: 267 GTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFS---------PNKLEFIKNLLNI 317

Query: 205 IDTIVLI-----ASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVV 259
           ID + ++       ++ +S+K   ++     LR +RF++ILR+ ++ R     ++LG  +
Sbjct: 318 IDFVAILPFYLEVGLSGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 375

Query: 260 YAHSKE-LITAWYIGFLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITL 309
            A + E L+   ++   VLIF++ + Y     A         + +F       WW  +T+
Sbjct: 376 RASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTM 435

Query: 310 TTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFAL 352
           TT+GYGD  P TW G L+ A  AL G+   A+P  ++ + F +
Sbjct: 436 TTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
           [Homo sapiens]
          Length = 757

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 57/224 (25%), Positives = 106/224 (47%), Gaps = 26/224 (11%)

Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214
           L  +E V +V F  EF++RI              ++ F +    +ID + ++       +
Sbjct: 348 LTYVEGVCVVWFTFEFLMRITFC---------PDKVEFLKSSLNIIDCVAILPFYLEVGL 398

Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273
           + +S+K   ++     LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++ 
Sbjct: 399 SGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 456

Query: 274 FLVLIFSSFLVYLVEKDANKE---------FSTYADALWWGTITLTTIGYGDKTPLTWLG 324
             VLIF++ + Y     A+ +         F       WW  +T+TT+GYGD  P TW G
Sbjct: 457 LGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 516

Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368
            L+ A  AL G+   A+P  ++ + F +       ++   K++N
Sbjct: 517 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKN 560


>gi|4826782 potassium voltage-gated channel, shaker-related
           subfamily, member 2 [Homo sapiens]
          Length = 499

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 51/199 (25%), Positives = 95/199 (47%), Gaps = 19/199 (9%)

Query: 162 ILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKT 221
           I+E + I+ F  EF++R ++            +  F      +ID + +I     +  + 
Sbjct: 224 IVETLCIIWFSFEFLVRFFAC---------PSKAGFFTNIMNIIDIVAIIPYFITLGTEL 274

Query: 222 --------QGN-IFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYI 272
                   QG    + + LR +R +++ R+ ++ R     ++LG  + A  +EL    + 
Sbjct: 275 AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFF 334

Query: 273 GFLVLIFSSFLVYLVEKDANK-EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGF 331
            F+ +I  S  VY  E D  + +F +  DA WW  +++TT+GYGD  P T  G+++ +  
Sbjct: 335 LFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLC 394

Query: 332 ALLGISFFALPAGILGSGF 350
           A+ G+   ALP  ++ S F
Sbjct: 395 AIAGVLTIALPVPVIVSNF 413


>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
           member 2 [Homo sapiens]
          Length = 630

 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 59/254 (23%), Positives = 116/254 (45%), Gaps = 31/254 (12%)

Query: 131 AFVFLLVFGCLI-LSVFSTIPEHTKLASS---------------CLLILEFVMIVVFGLE 174
           A VF  V G  I +SV + + E     SS                   L+   +++F +E
Sbjct: 184 ALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVE 243

Query: 175 FIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSL 234
           +++R+ +A           R RF R    +ID + ++     +      N   + A  +L
Sbjct: 244 YLLRLAAA---------PSRYRFVRSVMSIIDVVAILPYY--IGLVMTDNEDVSGAFVTL 292

Query: 235 RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIFSSFLVYLVEKDANK 293
           R  ++ R+ +  R     ++LG  + + + EL    + +   ++IF++ + Y  +  +  
Sbjct: 293 RVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSAS 352

Query: 294 EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALK 353
           +F++   A W+  +T+TT+GYGD  P T  G++  +  +L G+   ALP  ++ S F+  
Sbjct: 353 KFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFS-- 410

Query: 354 VQEQHRQKHFEKRR 367
            +  H+ +  +KRR
Sbjct: 411 -RIYHQNQRADKRR 423


>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
          Length = 500

 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 69/255 (27%), Positives = 117/255 (45%), Gaps = 28/255 (10%)

Query: 111 VQNYLYNVLERP------RGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILE 164
           V+  L+N+LE+P      R +  I   FV + +    ++S      E + L    L ILE
Sbjct: 192 VRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSA-----ELSWLDLQLLEILE 246

Query: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGN 224
           +V I  F  EF++R      C R      R RF RK   +ID + ++     +  ++   
Sbjct: 247 YVCISWFTGEFVLRF----LCVR-----DRCRFLRKVPNIIDLLAILPFYITLLVESLSG 297

Query: 225 IFATSALRS-------LRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLV 276
              T  L +       LR L+ LRM+++ R     + LG  +    +E+ +   ++   +
Sbjct: 298 SQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGI 357

Query: 277 LIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGI 336
            IFS+   +  +   +  F++   A WW T ++TT+GYGD  P T  G++++    L GI
Sbjct: 358 SIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGI 417

Query: 337 SFFALPAGILGSGFA 351
              ALP  I+   F+
Sbjct: 418 LVLALPIAIINDRFS 432


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,197,544
Number of Sequences: 37866
Number of extensions: 1396444
Number of successful extensions: 8292
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 7563
Number of HSP's gapped (non-prelim): 682
length of query: 822
length of database: 18,247,518
effective HSP length: 111
effective length of query: 711
effective length of database: 14,044,392
effective search space: 9985562712
effective search space used: 9985562712
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.