Search of human proteins with 236461942

Search of human proteins with 236461942

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|236461942 potassium voltage-gated channel, KQT-like
subfamily, member 5 isoform 3 [Homo sapiens]
         (942 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|236461942 potassium voltage-gated channel, KQT-like subfamily...  1866   0.0  
gi|236462079 potassium voltage-gated channel, KQT-like subfamily...  1856   0.0  
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,...  1818   0.0  
gi|236461719 potassium voltage-gated channel, KQT-like subfamily...  1816   0.0  
gi|236462242 potassium voltage-gated channel, KQT-like subfamily...   821   0.0  
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i...   754   0.0  
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i...   748   0.0  
gi|26051260 potassium voltage-gated channel KQT-like protein 2 i...   677   0.0  
gi|26051262 potassium voltage-gated channel KQT-like protein 2 i...   676   0.0  
gi|26051264 potassium voltage-gated channel KQT-like protein 2 i...   671   0.0  
gi|26051266 potassium voltage-gated channel KQT-like protein 2 i...   670   0.0  
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H...   582   e-166
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i...   472   e-133
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,...   411   e-114
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,...   382   e-106
gi|27436974 potassium voltage-gated channel, Shab-related subfam...    91   5e-18
gi|88758565 potassium voltage-gated channel, shaker-related subf...    90   9e-18
gi|119395748 potassium voltage-gated channel subfamily A member ...    89   1e-17
gi|4826784 potassium voltage-gated channel, Shab-related subfami...    87   7e-17
gi|4504817 potassium voltage-gated channel, shaker-related subfa...    87   7e-17
gi|88758576 Shaw-related voltage-gated potassium channel protein...    85   4e-16
gi|24497462 Shaw-related voltage-gated potassium channel protein...    85   4e-16
gi|24497464 Shaw-related voltage-gated potassium channel protein...    85   4e-16
gi|21217561 Shaw-related voltage-gated potassium channel protein...    84   5e-16
gi|21217563 Shaw-related voltage-gated potassium channel protein...    84   5e-16
gi|24497458 Shaw-related voltage-gated potassium channel protein...    84   5e-16
gi|24497460 Shaw-related voltage-gated potassium channel protein...    82   2e-15
gi|4826782 potassium voltage-gated channel, shaker-related subfa...    81   4e-15
gi|9789987 potassium voltage-gated channel, Shal-related subfami...    80   7e-15
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]     80   7e-15

>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 3 [Homo sapiens]
          Length = 942

 Score = 1866 bits (4833), Expect = 0.0
 Identities = 942/942 (100%), Positives = 942/942 (100%)

Query: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60
           MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
Sbjct: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120
           LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
Sbjct: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120

Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180
           RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180

Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240
           SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240

Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300
           RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300

Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360
           ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360

Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSNKQKLFRMY 420
           KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSNKQKLFRMY
Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSNKQKLFRMY 420

Query: 421 TSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR 480
           TSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR
Sbjct: 421 TSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR 480

Query: 481 TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF 540
           TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF
Sbjct: 481 TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF 540

Query: 541 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI 600
           HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI
Sbjct: 541 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI 600

Query: 601 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE 660
           TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE
Sbjct: 601 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE 660

Query: 661 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH 720
           CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH
Sbjct: 661 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH 720

Query: 721 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP 780
           SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP
Sbjct: 721 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP 780

Query: 781 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL 840
           AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL
Sbjct: 781 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL 840

Query: 841 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP 900
           SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP
Sbjct: 841 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP 900

Query: 901 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 942
           QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Sbjct: 901 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 942


>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 4 [Homo sapiens]
          Length = 951

 Score = 1856 bits (4808), Expect = 0.0
 Identities = 941/951 (98%), Positives = 942/951 (99%), Gaps = 9/951 (0%)

Query: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60
           MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
Sbjct: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120
           LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
Sbjct: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120

Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180
           RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180

Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240
           SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240

Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300
           RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300

Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360
           ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360

Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT---------NKFCS 411
           KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT         +KFCS
Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSKFCS 420

Query: 412 NKQKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKV 471
           NKQKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKV
Sbjct: 421 NKQKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKV 480

Query: 472 QKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTV 531
           QKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTV
Sbjct: 481 QKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTV 540

Query: 532 IRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIT 591
           IRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIT
Sbjct: 541 IRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIT 600

Query: 592 SDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALAL 651
           SDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALAL
Sbjct: 601 SDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALAL 660

Query: 652 ASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQT 711
           ASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQT
Sbjct: 661 ASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQT 720

Query: 712 FYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLP 771
           FYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLP
Sbjct: 721 FYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLP 780

Query: 772 RPETLHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPM 831
           RPETLHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPM
Sbjct: 781 RPETLHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPM 840

Query: 832 VPKDLGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEET 891
           VPKDLGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEET
Sbjct: 841 VPKDLGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEET 900

Query: 892 ETDTFDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 942
           ETDTFDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Sbjct: 901 ETDTFDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 951


>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 1 [Homo sapiens]
          Length = 932

 Score = 1818 bits (4709), Expect = 0.0
 Identities = 924/942 (98%), Positives = 924/942 (98%), Gaps = 10/942 (1%)

Query: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60
           MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
Sbjct: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120
           LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
Sbjct: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120

Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180
           RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180

Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240
           SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240

Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300
           RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300

Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360
           ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360

Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSNKQKLFRMY 420
           KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT K            
Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKK----------EQ 410

Query: 421 TSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR 480
                SQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR
Sbjct: 411 GEASSSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR 470

Query: 481 TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF 540
           TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF
Sbjct: 471 TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF 530

Query: 541 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI 600
           HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI
Sbjct: 531 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI 590

Query: 601 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE 660
           TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE
Sbjct: 591 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE 650

Query: 661 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH 720
           CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH
Sbjct: 651 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH 710

Query: 721 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP 780
           SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP
Sbjct: 711 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP 770

Query: 781 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL 840
           AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL
Sbjct: 771 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL 830

Query: 841 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP 900
           SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP
Sbjct: 831 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP 890

Query: 901 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 942
           QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Sbjct: 891 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 932


>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 2 [Homo sapiens]
          Length = 923

 Score = 1816 bits (4703), Expect = 0.0
 Identities = 923/942 (97%), Positives = 923/942 (97%), Gaps = 19/942 (2%)

Query: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60
           MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
Sbjct: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120
           LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
Sbjct: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120

Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180
           RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180

Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240
           SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240

Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300
           RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300

Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360
           ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360

Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSNKQKLFRMY 420
           KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTN             
Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTN------------- 407

Query: 421 TSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR 480
                 QKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR
Sbjct: 408 ------QKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR 461

Query: 481 TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF 540
           TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF
Sbjct: 462 TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF 521

Query: 541 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI 600
           HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI
Sbjct: 522 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI 581

Query: 601 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE 660
           TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE
Sbjct: 582 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE 641

Query: 661 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH 720
           CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH
Sbjct: 642 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH 701

Query: 721 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP 780
           SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP
Sbjct: 702 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP 761

Query: 781 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL 840
           AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL
Sbjct: 762 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL 821

Query: 841 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP 900
           SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP
Sbjct: 822 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP 881

Query: 901 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 942
           QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Sbjct: 882 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 923


>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 5 [Homo sapiens]
          Length = 822

 Score =  821 bits (2120), Expect = 0.0
 Identities = 411/437 (94%), Positives = 420/437 (96%), Gaps = 6/437 (1%)

Query: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60
           MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL
Sbjct: 1   MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120
           LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE
Sbjct: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120

Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180
           RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW
Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180

Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240
           SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL
Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240

Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300
           RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD
Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300

Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360
           ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ
Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360

Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSN-KQKLFRM 419
           KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT K       ++ + 
Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSRIMKF 420

Query: 420 YTSRKQSQKLSFKERVR 436
           + ++++     FKE +R
Sbjct: 421 HVAKRK-----FKETLR 432



 Score =  796 bits (2056), Expect = 0.0
 Identities = 407/407 (100%), Positives = 407/407 (100%)

Query: 536 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 595
           RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK
Sbjct: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 475

Query: 596 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 655
           SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ
Sbjct: 476 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 535

Query: 656 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 715
           IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL
Sbjct: 536 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 595

Query: 716 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 775
           SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET
Sbjct: 596 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 655

Query: 776 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 835
           LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD
Sbjct: 656 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 715

Query: 836 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 895
           LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT
Sbjct: 716 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 775

Query: 896 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 942
           FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Sbjct: 776 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 822


>gi|26638655 potassium voltage-gated channel KQT-like protein 4
           isoform b [Homo sapiens]
          Length = 641

 Score =  754 bits (1948), Expect = 0.0
 Identities = 408/646 (63%), Positives = 484/646 (74%), Gaps = 63/646 (9%)

Query: 70  GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115
           GGGG  R         R+ LLG PL              S    +S   + +YRR+QN++
Sbjct: 37  GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87

Query: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175
           YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 88  YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147

Query: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235
           I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207

Query: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295
           FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267

Query: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355
           S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327

Query: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATWKPHLKALHTCSPTNKFCSNKQ 414
           EQHRQKHFEKRR PAANLIQ  WR Y+ D  ++   ATW  +   L +            
Sbjct: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSF----------- 376

Query: 415 KLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQ--ASVGDRRSPSTDITAEG-SPTKV 471
                      S ++  K+R+RM S + ++  S+Q  A      SPS++   E  SPTKV
Sbjct: 377 -----------SSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKV 425

Query: 472 QKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTV 531
           QKSWSFNDRTRFR SLRL     KP   A+ A  +++V +EK  QC+++V+D+ P +KTV
Sbjct: 426 QKSWSFNDRTRFRASLRL-----KPRTSAEDA-PSEEVAEEKSYQCELTVDDIMPAVKTV 479

Query: 532 IRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIT 591
           IR+IRI+KF VAKRKFKETLRPYDVKDVIEQYSAGHLDML RIKSLQTRVDQI+G+G   
Sbjct: 480 IRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--P 537

Query: 592 SDKKSRE---KITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASA 648
            D+K+RE   K  ++ E  D++SM+GRVVKVEKQVQSIE KLD LL  Y + LR G+++ 
Sbjct: 538 GDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA- 596

Query: 649 LALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 694
            +L + Q+P F+ + TSDY SPVD +D+S SAQ    +SRS S N+
Sbjct: 597 -SLGAVQVPLFDPDITSDYHSPVDHEDISVSAQTLS-ISRSVSTNM 640


>gi|26638653 potassium voltage-gated channel KQT-like protein 4
           isoform a [Homo sapiens]
          Length = 695

 Score =  748 bits (1931), Expect = 0.0
 Identities = 411/678 (60%), Positives = 491/678 (72%), Gaps = 73/678 (10%)

Query: 70  GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115
           GGGG  R         R+ LLG PL              S    +S   + +YRR+QN++
Sbjct: 37  GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87

Query: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175
           YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+
Sbjct: 88  YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147

Query: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235
           I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R
Sbjct: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207

Query: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295
           FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F
Sbjct: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267

Query: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355
           S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ
Sbjct: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327

Query: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATWKPHLKALHTCSPTNKFCSNKQ 414
           EQHRQKHFEKRR PAANLIQ  WR Y+ D  ++   ATW  +   L +         + Q
Sbjct: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQ 387

Query: 415 KL----FRMYTSRK----------------------------QSQKLSFKERVRMASPRG 442
           +      R    R+                            +S ++  K+R+RM S + 
Sbjct: 388 RARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQR 447

Query: 443 QSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID 499
           ++  S+Q  A      SPS++   E  SPTKVQKSWSFNDRTRFR SLRL     KP   
Sbjct: 448 RTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL-----KPRTS 502

Query: 500 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV 559
           A+ A  +++V +EK  QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDVKDV
Sbjct: 503 AEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDV 561

Query: 560 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETTDDLSMLGRV 616
           IEQYSAGHLDML RIKSLQTRVDQI+G+G    D+K+RE   K  ++ E  D++SM+GRV
Sbjct: 562 IEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVVDEISMMGRV 619

Query: 617 VKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDL 676
           VKVEKQVQSIE KLD LL  Y + LR G+++  +L + Q+P F+ + TSDY SPVD +D+
Sbjct: 620 VKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDHEDI 677

Query: 677 SGSAQNSGCLSRSTSANI 694
           S SAQ    +SRS S N+
Sbjct: 678 SVSAQTLS-ISRSVSTNM 694


>gi|26051260 potassium voltage-gated channel KQT-like protein 2
           isoform c [Homo sapiens]
          Length = 844

 Score =  677 bits (1748), Expect = 0.0
 Identities = 378/671 (56%), Positives = 460/671 (68%), Gaps = 46/671 (6%)

Query: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77

Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137

Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197

Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257

Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317

Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTNKFC 410
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +    P  +  
Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTV--PMYRLI 375

Query: 411 S--NKQKLFRMYTSR-------------KQSQKLSFKERVRMASPRGQSIKSRQASVGD- 454
              N+ +L R   S+               SQK+S K+RV  +SPRG + K + +     
Sbjct: 376 PPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKGKGSPQAQT 434

Query: 455 -RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEK 513
            RRSPS D + E SP+KV KSWSF DR+R R + R+K +  +   + + +L  +D+ D+K
Sbjct: 435 VRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLPGEDIVDDK 493

Query: 514 GCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCR 573
            C C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML R
Sbjct: 494 SCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSR 553

Query: 574 IKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCL 633
           IKSLQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S+E KLD L
Sbjct: 554 IKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFL 612

Query: 634 LDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSAN 693
           ++IY Q  R G       A F     E E    Y SP DS++        GC+ +   ++
Sbjct: 613 VNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSS 665

Query: 694 ISRGLQFILTP 704
            S G +    P
Sbjct: 666 SSTGQKNFSAP 676


>gi|26051262 potassium voltage-gated channel KQT-like protein 2
           isoform b [Homo sapiens]
          Length = 854

 Score =  676 bits (1745), Expect = 0.0
 Identities = 379/679 (55%), Positives = 462/679 (68%), Gaps = 52/679 (7%)

Query: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77

Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137

Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197

Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257

Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317

Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHT---CSPTN 407
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +      S T 
Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377

Query: 408 KFCS-------NKQKLFRMYTSR-------------KQSQKLSFKERVRMASPRGQSIKS 447
            + +       N+ +L R   S+               SQK+S K+RV  +SPRG + K 
Sbjct: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKG 436

Query: 448 RQASVGD--RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALG 505
           + +      RRSPS D + E SP+KV KSWSF DR+R R + R+K +  +   + + +L 
Sbjct: 437 KGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLP 495

Query: 506 TDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSA 565
            +D+ D+K C C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSA
Sbjct: 496 GEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSA 555

Query: 566 GHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQS 625
           GHLDML RIKSLQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S
Sbjct: 556 GHLDMLSRIKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLS 614

Query: 626 IESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGC 685
           +E KLD L++IY Q  R G       A F     E E    Y SP DS++        GC
Sbjct: 615 MEKKLDFLVNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGC 667

Query: 686 LSRSTSANISRGLQFILTP 704
           + +   ++ S G +    P
Sbjct: 668 IVKIVRSSSSTGQKNFSAP 686


>gi|26051264 potassium voltage-gated channel KQT-like protein 2
           isoform a [Homo sapiens]
          Length = 872

 Score =  671 bits (1730), Expect = 0.0
 Identities = 379/697 (54%), Positives = 463/697 (66%), Gaps = 70/697 (10%)

Query: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77

Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137

Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197

Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257

Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317

Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHT---CSPTN 407
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +      S T 
Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377

Query: 408 KFCS-------NKQKLFRMYTSR-------------------------------KQSQKL 429
            + +       N+ +L R   S+                               + SQK+
Sbjct: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSKGSPCRGPLCGCCPGRSSQKV 437

Query: 430 SFKERVRMASPRGQSIKSRQASVGD--RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSL 487
           S K+RV  +SPRG + K + +      RRSPS D + E SP+KV KSWSF DR+R R + 
Sbjct: 438 SLKDRV-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAF 496

Query: 488 RLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKF 547
           R+K +  +   + + +L  +D+ D+K C C+   EDLTP LK  IRA+ +M+F V+KRKF
Sbjct: 497 RIKGAASRQNSE-EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKF 555

Query: 548 KETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETT 607
           KE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQI+G+G   +D K R K  AE E  
Sbjct: 556 KESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELP 614

Query: 608 DDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDY 667
           +D SM+GR+ KVEKQV S+E KLD L++IY Q  R G       A F     E E    Y
Sbjct: 615 EDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPY 670

Query: 668 QSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTP 704
            SP DS++        GC+ +   ++ S G +    P
Sbjct: 671 HSPEDSRE---HVDRHGCIVKIVRSSSSTGQKNFSAP 704


>gi|26051266 potassium voltage-gated channel KQT-like protein 2
           isoform d [Homo sapiens]
          Length = 841

 Score =  670 bits (1729), Expect = 0.0
 Identities = 371/666 (55%), Positives = 456/666 (68%), Gaps = 39/666 (5%)

Query: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77

Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137

Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197

Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257

Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317

Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHT---CSPTN 407
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +      S T 
Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377

Query: 408 KFCSNK----QKLFRMYTSRKQSQKLSFKE---RVRMASPRGQSIKSRQASVGD--RRSP 458
            + +++         +  + K    L+F++        SPRG + K + +      RRSP
Sbjct: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSP 437

Query: 459 STDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCD 518
           S D + E SP+KV KSWSF DR+R R + R+K +  +   +++ +L  +D+ D+K C C+
Sbjct: 438 SADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQ--NSEASLPGEDIVDDKSCPCE 495

Query: 519 VSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQ 578
              EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ
Sbjct: 496 FVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQ 555

Query: 579 TRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQ 638
           +RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++IY 
Sbjct: 556 SRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYM 614

Query: 639 QVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGL 698
           Q  R G       A F     E E    Y SP DS++        GC+ +   ++ S G 
Sbjct: 615 Q--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQ 667

Query: 699 QFILTP 704
           +    P
Sbjct: 668 KNFSAP 673


>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
           sapiens]
          Length = 872

 Score =  582 bits (1500), Expect = e-166
 Identities = 339/675 (50%), Positives = 422/675 (62%), Gaps = 77/675 (11%)

Query: 7   GGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGR------VLLNSAAARGDGLLL 60
           GG +GG  G     G AA  AGG    +G ++ + G          L   A A  DG LL
Sbjct: 14  GGGDGGGGG-----GGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLL 68

Query: 61  LGTRAATLGGGGGGLRESRRGKQGARMSLLGK-PLSYTSSQSCRRNVKYRRVQNYLYNVL 119
           L         GGG     RR  QG  + LL K PLS       R N KYRR+Q  +Y+ L
Sbjct: 69  L--------EGGGRDEGQRRTPQG--IGLLAKTPLSRPVK---RNNAKYRRIQTLIYDAL 115

Query: 120 ERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRI 179
           ERPRGWA +YHA VFL+V GCLIL+V +T  E+  ++   LL+LE   I +FG EF +RI
Sbjct: 116 ERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRI 175

Query: 180 WSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQI 239
           W+AGCCCRY+GW+GRL+FARKP C++D  VLIAS+ VV+   QGN+ ATS LRSLRFLQI
Sbjct: 176 WAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS-LRSLRFLQI 234

Query: 240 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-------- 291
           LRM+RMDRRGGTWKLLGS + AHSKELITAWYIGFL LI SSFLVYLVEKD         
Sbjct: 235 LRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGE 294

Query: 292 --NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSG 349
              +EF TYADALWWG ITL TIGYGDKTP TW GRL++A F+L+G+SFFALPAGILGSG
Sbjct: 295 EMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSG 354

Query: 350 FALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVS-IATWKPHLKALHTCSPTNK 408
            ALKVQEQHRQKHFEKRR PAA LIQ  WR YA +   +  +ATW+      +    +  
Sbjct: 355 LALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWR-----FYESVVSFP 409

Query: 409 FCSNKQKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSP 468
           F   +Q           SQKL   +RVR+++PRG + K      G   +P      E SP
Sbjct: 410 FFRKEQ------LEAASSQKLGLLDRVRLSNPRGSNTK------GKLFTPLNVDAIEESP 457

Query: 469 TKVQKSWSFNDRTRFRPSLRLKS-SQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPP 527
           +K  K    N++ RFR + R+K+ +  +   DA T    D + +++G   D  +ED+ P 
Sbjct: 458 SKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTG---DPMAEDRGYGNDFPIEDMIPT 514

Query: 528 LKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGK 587
           LK  IRA+RI++F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQTR+D I   
Sbjct: 515 LKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTP 574

Query: 588 GQITSDKKSR-----------------EKITAEHETT--DDLSMLGRVVKVEKQVQSIES 628
           G  ++ K  +                 E   A   T+  +D SM+G+ VKVE+QVQ +  
Sbjct: 575 GPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGK 634

Query: 629 KLDCLLDIYQQVLRK 643
           KLD L+D++ Q + +
Sbjct: 635 KLDFLVDMHMQHMER 649


>gi|26051268 potassium voltage-gated channel KQT-like protein 2
           isoform e [Homo sapiens]
          Length = 393

 Score =  472 bits (1214), Expect = e-133
 Identities = 238/344 (69%), Positives = 271/344 (78%), Gaps = 17/344 (4%)

Query: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77

Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137

Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197

Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257

Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317

Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWK 394
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+
Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQ 361


>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 1 [Homo sapiens]
          Length = 676

 Score =  411 bits (1056), Expect = e-114
 Identities = 241/556 (43%), Positives = 341/556 (61%), Gaps = 42/556 (7%)

Query: 98  SSQSCRRNVKYR-RVQNYLYNVLERPRGW-AFIYHAFVFLLVFGCLILSVFSTIPEHTKL 155
           S  S RR V  R  VQ  +YN LERP GW  F+YH  VFL+V  CLI SV STI ++  L
Sbjct: 92  SIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAAL 151

Query: 156 ASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIA 215
           A+  L  +E V++V FG E+++R+WSAGC  +Y G  GRLRFARKP  +ID IV++AS+ 
Sbjct: 152 ATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMV 211

Query: 216 VVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFL 275
           V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVV+ H +ELIT  YIGFL
Sbjct: 212 VLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFL 271

Query: 276 VLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAG 330
            LIFSS+ VYL EKDA       EF +YADALWWG +T+TTIGYGDK P TW+G+ +++ 
Sbjct: 272 GLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASC 331

Query: 331 FALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI 390
           F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++   AA+LIQ  WR YAA+    S 
Sbjct: 332 FSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSS- 390

Query: 391 ATWKPHLKALHTCSPTNKFCSNKQKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQA 450
            TWK +++                K  R +T    S K   K+ V +   + +  K    
Sbjct: 391 -TWKIYIR----------------KAPRSHTLLSPSPKP--KKSVVVKKKKFKLDKDNGV 431

Query: 451 SVGDRRSPSTDITAEGSPTKVQKSWS---FNDRTRFRPSLRLKSSQPKPVIDADTALGTD 507
           + G++      IT +    +    +S   ++   R  P+L L+ S P   +  ++     
Sbjct: 432 TPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL-LEVSMPH-FMRTNSFAEDL 489

Query: 508 DVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGH 567
           D+  E        +  L    +  I+ IR M++ VAK+KF++  +PYDV+DVIEQYS GH
Sbjct: 490 DLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGH 549

Query: 568 LDMLCRIKSLQTRVDQILGKGQ--ITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQS 625
           L+++ RIK LQ R+DQ +GK    I+  +KS+++           ++  R+ +VE +V  
Sbjct: 550 LNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDR--------GSNTIGARLNRVEDKVTQ 601

Query: 626 IESKLDCLLDIYQQVL 641
           ++ +L  + D+  Q+L
Sbjct: 602 LDQRLALITDMLHQLL 617


>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 2 [Homo sapiens]
          Length = 549

 Score =  382 bits (982), Expect = e-106
 Identities = 221/518 (42%), Positives = 319/518 (61%), Gaps = 40/518 (7%)

Query: 134 FLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQG 193
           FL+V  CLI SV STI ++  LA+  L  +E V++V FG E+++R+WSAGC  +Y G  G
Sbjct: 3   FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62

Query: 194 RLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWK 253
           RLRFARKP  +ID IV++AS+ V+   ++G +FATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 63  RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122

Query: 254 LLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTIT 308
           LLGSVV+ H +ELIT  YIGFL LIFSS+ VYL EKDA       EF +YADALWWG +T
Sbjct: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182

Query: 309 LTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368
           +TTIGYGDK P TW+G+ +++ F++  ISFFALPAGILGSGFALKVQ++ RQKHF ++  
Sbjct: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242

Query: 369 PAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSNKQKLFRMYTSRKQSQK 428
            AA+LIQ  WR YAA+    S  TWK +++                K  R +T    S K
Sbjct: 243 AAASLIQTAWRCYAAENPDSS--TWKIYIR----------------KAPRSHTLLSPSPK 284

Query: 429 LSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWS---FNDRTRFRP 485
              K+ V +   + +  K    + G++      IT +    +    +S   ++   R  P
Sbjct: 285 P--KKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSP 342

Query: 486 SLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKR 545
           +L L+ S P   +  ++     D+  E        +  L    +  I+ IR M++ VAK+
Sbjct: 343 TL-LEVSMPH-FMRTNSFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKK 400

Query: 546 KFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQ--ITSDKKSREKITAE 603
           KF++  +PYDV+DVIEQYS GHL+++ RIK LQ R+DQ +GK    I+  +KS+++    
Sbjct: 401 KFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDR---- 456

Query: 604 HETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVL 641
                  ++  R+ +VE +V  ++ +L  + D+  Q+L
Sbjct: 457 ----GSNTIGARLNRVEDKVTQLDQRLALITDMLHQLL 490


>gi|27436974 potassium voltage-gated channel, Shab-related
           subfamily, member 2 [Homo sapiens]
          Length = 911

 Score = 90.9 bits (224), Expect = 5e-18
 Identities = 93/393 (23%), Positives = 173/393 (44%), Gaps = 58/393 (14%)

Query: 115 LYNVLERPRGWA---FIYHAFVFLLVFGCLILSVFSTIPEHTKLA-------SSCLLILE 164
           L+++LE+P        +    +  +V   + LS+ +T+PE  +         +  L  +E
Sbjct: 179 LWDLLEKPNSSVAAKILAIVSILFIVLSTIALSL-NTLPELQETDEFGQLNDNRQLAHVE 237

Query: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIAS-IAVVSAKTQG 223
            V I  F +E+++R  S+           + +F + P  VID + ++   + +   ++  
Sbjct: 238 AVCIAWFTMEYLLRFLSS---------PNKWKFFKGPLNVIDLLAILPYYVTIFLTESNK 288

Query: 224 NIFATSALRSL----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLI 278
           ++     +R +    R ++ILR++++ R     + LG  +     EL +   ++   ++I
Sbjct: 289 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 348

Query: 279 FSSFLVYLVEKDANK-EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGIS 337
           FSS LV+  EKD +  +F++   + WW TIT+TT+GYGD  P T LG+++     + G+ 
Sbjct: 349 FSS-LVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL 407

Query: 338 FFALPAGILGSGFALKVQEQHRQKHFEKRRNP-----------AANLIQCVWRSY----- 381
             ALP  I+ + F+   +EQ RQ+   KRR             + NL     RS      
Sbjct: 408 VIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARSMELIDV 467

Query: 382 -------------AADEKSVSIATWKPHLKALHTCSPTNKFCSNKQKLFRMYTSRKQSQK 428
                        +AD+  +S + WK   KAL   S +NK   NK +      S +Q   
Sbjct: 468 AVEKAGESANTKDSADDNHLSPSRWKWARKALSETS-SNKSFENKYQEVSQKDSHEQLNN 526

Query: 429 LSFKERVRMASPRGQSIKSRQASVGDRRSPSTD 461
            S      +++ + + + +          P+ D
Sbjct: 527 TSSSSPQHLSAQKLEMLYNEITKTQPHSHPNPD 559


>gi|88758565 potassium voltage-gated channel, shaker-related
           subfamily, member 3 [Homo sapiens]
          Length = 575

 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 53/201 (26%), Positives = 103/201 (51%), Gaps = 16/201 (7%)

Query: 157 SSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIA---S 213
           S    ++E + I+ F  E ++R ++            +  F+R    +ID + +I    +
Sbjct: 292 SDPFFVVETLCIIWFSFELLVRFFAC---------PSKATFSRNIMNLIDIVAIIPYFIT 342

Query: 214 IAVVSAKTQGN---IFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITA 269
           +    A+ QGN     + + LR +R +++ R+ ++ R     ++LG  + A  +EL +  
Sbjct: 343 LGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 402

Query: 270 WYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSA 329
           +++   V++FSS + +    D    FS+  DA WW  +T+TT+GYGD  P+T  G+++ +
Sbjct: 403 FFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGS 462

Query: 330 GFALLGISFFALPAGILGSGF 350
             A+ G+   ALP  ++ S F
Sbjct: 463 LCAIAGVLTIALPVPVIVSNF 483


>gi|119395748 potassium voltage-gated channel subfamily A member 1
           [Homo sapiens]
          Length = 495

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 66/294 (22%), Positives = 134/294 (45%), Gaps = 34/294 (11%)

Query: 147 STIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVID 206
           +T+  ++ + +    I+E + I+ F  E ++R ++            +  F +     ID
Sbjct: 208 TTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFAC---------PSKTDFFKNIMNFID 258

Query: 207 TIVLIA---SIAVVSAKTQGNIFATSA-----LRSLRFLQILRMVRMDRRGGTWKLLGSV 258
            + +I    ++    A+ +GN     A     LR +R +++ R+ ++ R     ++LG  
Sbjct: 259 IVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQT 318

Query: 259 VYAHSKEL-ITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDK 317
           + A  +EL +  +++   V++FSS + +   ++A   FS+  DA WW  +++TT+GYGD 
Sbjct: 319 LKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDM 378

Query: 318 TPLTWLGRLLSAGFALLGISFFALPAGILGSGF---------------ALKVQEQHRQKH 362
            P+T  G+++ +  A+ G+   ALP  ++ S F                L V   +    
Sbjct: 379 YPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLLHVSSPNLASD 438

Query: 363 FEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSNKQKL 416
            +  R  ++ + +  +     D  + SIA ++        C+  N+ C NK KL
Sbjct: 439 SDLSRRSSSTMSKSEYMEIEEDMNN-SIAHYRQVNIRTANCTTANQNCVNKSKL 491


>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
           member 1 [Homo sapiens]
          Length = 858

 Score = 87.0 bits (214), Expect = 7e-17
 Identities = 72/270 (26%), Positives = 134/270 (49%), Gaps = 28/270 (10%)

Query: 115 LYNVLERPRGWA---FIYHAFVFLLVFGCLILSVFSTIPEHTKLA-------SSCLLILE 164
           L+++LE+P        +    +  +V   + LS+ +T+PE   L        +  L  +E
Sbjct: 175 LWDLLEKPNSSVAAKILAIISIMFIVLSTIALSL-NTLPELQSLDEFGQSTDNPQLAHVE 233

Query: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIAS-IAVVSAKTQG 223
            V I  F +E+++R  S+      + W    +F + P   ID + ++   + +   ++  
Sbjct: 234 AVCIAWFTMEYLLRFLSSP-----KKW----KFFKGPLNAIDLLAILPYYVTIFLTESNK 284

Query: 224 NIFATSALRSL----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLI 278
           ++     +R +    R ++ILR++++ R     + LG  +     EL +   ++   ++I
Sbjct: 285 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 344

Query: 279 FSSFLVYLVEKDANK-EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGIS 337
           FSS LV+  EKD +  +F +   + WW TIT+TT+GYGD  P T LG+++     + G+ 
Sbjct: 345 FSS-LVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL 403

Query: 338 FFALPAGILGSGFALKVQEQHRQKHFEKRR 367
             ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 404 VIALPIPIIVNNFSEFYKEQKRQEKAIKRR 433


>gi|4504817 potassium voltage-gated channel, shaker-related
           subfamily, member 4 [Homo sapiens]
          Length = 653

 Score = 87.0 bits (214), Expect = 7e-17
 Identities = 59/226 (26%), Positives = 105/226 (46%), Gaps = 23/226 (10%)

Query: 162 ILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVS--- 218
           I+E V IV F  EF++R ++            +  F +    +ID + ++     +    
Sbjct: 373 IVETVCIVWFSFEFVVRCFAC---------PSQALFFKNIMNIIDIVSILPYFITLGTDL 423

Query: 219 AKTQGN-------IFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWY 271
           A+ QG          + + LR +R +++ R+ ++ R     ++LG  + A  +EL    +
Sbjct: 424 AQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIF 483

Query: 272 IGFLVLIFSSFLVYLVEKDA-NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAG 330
             F+ +I  S  VY  E D     F +  DA WW  +T+TT+GYGD  P+T  G+++ + 
Sbjct: 484 FLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSL 543

Query: 331 FALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQC 376
            A+ G+   ALP  ++ S F       HR+   E++     N + C
Sbjct: 544 CAIAGVLTIALPVPVIVSNFN---YFYHRETENEEQTQLTQNAVSC 586


>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
           isoform c [Homo sapiens]
          Length = 626

 Score = 84.7 bits (208), Expect = 4e-16
 Identities = 60/223 (26%), Positives = 107/223 (47%), Gaps = 26/223 (11%)

Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214
           L  +E V ++ F LEF++RI     CC        L F +    +ID + ++       +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAILPFYLEVGL 331

Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273
           + +S+K   ++     LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++ 
Sbjct: 332 SGLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389

Query: 274 FLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITLTTIGYGDKTPLTWLG 324
             VLIF++ + Y     A         + +F       WW  +T+TT+GYGD  P TW G
Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 449

Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 367
            L+ A  AL G+   A+P  ++ + F +       ++   K+R
Sbjct: 450 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
           isoform a [Homo sapiens]
          Length = 635

 Score = 84.7 bits (208), Expect = 4e-16
 Identities = 60/223 (26%), Positives = 107/223 (47%), Gaps = 26/223 (11%)

Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214
           L  +E V ++ F LEF++RI     CC        L F +    +ID + ++       +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAILPFYLEVGL 331

Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273
           + +S+K   ++     LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++ 
Sbjct: 332 SGLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389

Query: 274 FLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITLTTIGYGDKTPLTWLG 324
             VLIF++ + Y     A         + +F       WW  +T+TT+GYGD  P TW G
Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 449

Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 367
            L+ A  AL G+   A+P  ++ + F +       ++   K+R
Sbjct: 450 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
           isoform b [Homo sapiens]
          Length = 582

 Score = 84.7 bits (208), Expect = 4e-16
 Identities = 60/223 (26%), Positives = 107/223 (47%), Gaps = 26/223 (11%)

Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214
           L  +E V ++ F LEF++RI     CC        L F +    +ID + ++       +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAILPFYLEVGL 331

Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273
           + +S+K   ++     LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++ 
Sbjct: 332 SGLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389

Query: 274 FLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITLTTIGYGDKTPLTWLG 324
             VLIF++ + Y     A         + +F       WW  +T+TT+GYGD  P TW G
Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 449

Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRR 367
            L+ A  AL G+   A+P  ++ + F +       ++   K+R
Sbjct: 450 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2a [Homo sapiens]
          Length = 613

 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 69/283 (24%), Positives = 129/283 (45%), Gaps = 48/283 (16%)

Query: 107 KYRRVQNYLYNVLERP---RGWAFIYHAFVFLLVFG----CL---------------ILS 144
           ++RR+Q  ++ + E P   R   FI  A +F ++      CL               +++
Sbjct: 207 RWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVIN 266

Query: 145 VFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV 204
             S + ++       L  +E V +V F  EF++RI  +           +L F +    +
Sbjct: 267 GTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFS---------PNKLEFIKNLLNI 317

Query: 205 IDTIVLI-----ASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVV 259
           ID + ++       ++ +S+K   ++     LR +RF++ILR+ ++ R     ++LG  +
Sbjct: 318 IDFVAILPFYLEVGLSGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 375

Query: 260 YAHSKE-LITAWYIGFLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITL 309
            A + E L+   ++   VLIF++ + Y     A         + +F       WW  +T+
Sbjct: 376 RASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTM 435

Query: 310 TTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFAL 352
           TT+GYGD  P TW G L+ A  AL G+   A+P  ++ + F +
Sbjct: 436 TTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2b [Homo sapiens]
          Length = 638

 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 69/283 (24%), Positives = 129/283 (45%), Gaps = 48/283 (16%)

Query: 107 KYRRVQNYLYNVLERP---RGWAFIYHAFVFLLVFG----CL---------------ILS 144
           ++RR+Q  ++ + E P   R   FI  A +F ++      CL               +++
Sbjct: 207 RWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVIN 266

Query: 145 VFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV 204
             S + ++       L  +E V +V F  EF++RI  +           +L F +    +
Sbjct: 267 GTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFS---------PNKLEFIKNLLNI 317

Query: 205 IDTIVLI-----ASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVV 259
           ID + ++       ++ +S+K   ++     LR +RF++ILR+ ++ R     ++LG  +
Sbjct: 318 IDFVAILPFYLEVGLSGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 375

Query: 260 YAHSKE-LITAWYIGFLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITL 309
            A + E L+   ++   VLIF++ + Y     A         + +F       WW  +T+
Sbjct: 376 RASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTM 435

Query: 310 TTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFAL 352
           TT+GYGD  P TW G L+ A  AL G+   A+P  ++ + F +
Sbjct: 436 TTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2c [Homo sapiens]
          Length = 558

 Score = 84.3 bits (207), Expect = 5e-16
 Identities = 69/283 (24%), Positives = 129/283 (45%), Gaps = 48/283 (16%)

Query: 107 KYRRVQNYLYNVLERP---RGWAFIYHAFVFLLVFG----CL---------------ILS 144
           ++RR+Q  ++ + E P   R   FI  A +F ++      CL               +++
Sbjct: 207 RWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVIN 266

Query: 145 VFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV 204
             S + ++       L  +E V +V F  EF++RI  +           +L F +    +
Sbjct: 267 GTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFS---------PNKLEFIKNLLNI 317

Query: 205 IDTIVLI-----ASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVV 259
           ID + ++       ++ +S+K   ++     LR +RF++ILR+ ++ R     ++LG  +
Sbjct: 318 IDFVAILPFYLEVGLSGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 375

Query: 260 YAHSKE-LITAWYIGFLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITL 309
            A + E L+   ++   VLIF++ + Y     A         + +F       WW  +T+
Sbjct: 376 RASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTM 435

Query: 310 TTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFAL 352
           TT+GYGD  P TW G L+ A  AL G+   A+P  ++ + F +
Sbjct: 436 TTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
           [Homo sapiens]
          Length = 757

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 57/224 (25%), Positives = 106/224 (47%), Gaps = 26/224 (11%)

Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214
           L  +E V +V F  EF++RI              ++ F +    +ID + ++       +
Sbjct: 348 LTYVEGVCVVWFTFEFLMRITFC---------PDKVEFLKSSLNIIDCVAILPFYLEVGL 398

Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273
           + +S+K   ++     LR +RF++ILR+ ++ R     ++LG  + A + E L+   ++ 
Sbjct: 399 SGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 456

Query: 274 FLVLIFSSFLVYLVEKDANKE---------FSTYADALWWGTITLTTIGYGDKTPLTWLG 324
             VLIF++ + Y     A+ +         F       WW  +T+TT+GYGD  P TW G
Sbjct: 457 LGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 516

Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368
            L+ A  AL G+   A+P  ++ + F +       ++   K++N
Sbjct: 517 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKN 560


>gi|4826782 potassium voltage-gated channel, shaker-related
           subfamily, member 2 [Homo sapiens]
          Length = 499

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 51/199 (25%), Positives = 95/199 (47%), Gaps = 19/199 (9%)

Query: 162 ILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKT 221
           I+E + I+ F  EF++R ++            +  F      +ID + +I     +  + 
Sbjct: 224 IVETLCIIWFSFEFLVRFFAC---------PSKAGFFTNIMNIIDIVAIIPYFITLGTEL 274

Query: 222 --------QGN-IFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYI 272
                   QG    + + LR +R +++ R+ ++ R     ++LG  + A  +EL    + 
Sbjct: 275 AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFF 334

Query: 273 GFLVLIFSSFLVYLVEKDANK-EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGF 331
            F+ +I  S  VY  E D  + +F +  DA WW  +++TT+GYGD  P T  G+++ +  
Sbjct: 335 LFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLC 394

Query: 332 ALLGISFFALPAGILGSGF 350
           A+ G+   ALP  ++ S F
Sbjct: 395 AIAGVLTIALPVPVIVSNF 413


>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
           member 2 [Homo sapiens]
          Length = 630

 Score = 80.5 bits (197), Expect = 7e-15
 Identities = 59/254 (23%), Positives = 116/254 (45%), Gaps = 31/254 (12%)

Query: 131 AFVFLLVFGCLI-LSVFSTIPEHTKLASS---------------CLLILEFVMIVVFGLE 174
           A VF  V G  I +SV + + E     SS                   L+   +++F +E
Sbjct: 184 ALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVE 243

Query: 175 FIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSL 234
           +++R+ +A           R RF R    +ID + ++     +      N   + A  +L
Sbjct: 244 YLLRLAAA---------PSRYRFVRSVMSIIDVVAILPYY--IGLVMTDNEDVSGAFVTL 292

Query: 235 RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIFSSFLVYLVEKDANK 293
           R  ++ R+ +  R     ++LG  + + + EL    + +   ++IF++ + Y  +  +  
Sbjct: 293 RVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSAS 352

Query: 294 EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALK 353
           +F++   A W+  +T+TT+GYGD  P T  G++  +  +L G+   ALP  ++ S F+  
Sbjct: 353 KFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFS-- 410

Query: 354 VQEQHRQKHFEKRR 367
            +  H+ +  +KRR
Sbjct: 411 -RIYHQNQRADKRR 423


>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
          Length = 500

 Score = 80.5 bits (197), Expect = 7e-15
 Identities = 69/255 (27%), Positives = 117/255 (45%), Gaps = 28/255 (10%)

Query: 111 VQNYLYNVLERP------RGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILE 164
           V+  L+N+LE+P      R +  I   FV + +    ++S      E + L    L ILE
Sbjct: 192 VRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSA-----ELSWLDLQLLEILE 246

Query: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGN 224
           +V I  F  EF++R      C R      R RF RK   +ID + ++     +  ++   
Sbjct: 247 YVCISWFTGEFVLRF----LCVR-----DRCRFLRKVPNIIDLLAILPFYITLLVESLSG 297

Query: 225 IFATSALRS-------LRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLV 276
              T  L +       LR L+ LRM+++ R     + LG  +    +E+ +   ++   +
Sbjct: 298 SQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGI 357

Query: 277 LIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGI 336
            IFS+   +  +   +  F++   A WW T ++TT+GYGD  P T  G++++    L GI
Sbjct: 358 SIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGI 417

Query: 337 SFFALPAGILGSGFA 351
              ALP  I+   F+
Sbjct: 418 LVLALPIAIINDRFS 432


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,831,721
Number of Sequences: 37866
Number of extensions: 1621624
Number of successful extensions: 8861
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 109
Number of HSP's that attempted gapping in prelim test: 8123
Number of HSP's gapped (non-prelim): 659
length of query: 942
length of database: 18,247,518
effective HSP length: 112
effective length of query: 830
effective length of database: 14,006,526
effective search space: 11625416580
effective search space used: 11625416580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.