BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|236461719 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 2 [Homo sapiens] (923 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|236461719 potassium voltage-gated channel, KQT-like subfamily... 1827 0.0 gi|28373065 potassium voltage-gated channel, KQT-like subfamily,... 1818 0.0 gi|236461942 potassium voltage-gated channel, KQT-like subfamily... 1816 0.0 gi|236462079 potassium voltage-gated channel, KQT-like subfamily... 1810 0.0 gi|236462242 potassium voltage-gated channel, KQT-like subfamily... 819 0.0 gi|26638655 potassium voltage-gated channel KQT-like protein 4 i... 762 0.0 gi|26638653 potassium voltage-gated channel KQT-like protein 4 i... 746 0.0 gi|26051260 potassium voltage-gated channel KQT-like protein 2 i... 672 0.0 gi|26051262 potassium voltage-gated channel KQT-like protein 2 i... 668 0.0 gi|26051266 potassium voltage-gated channel KQT-like protein 2 i... 667 0.0 gi|26051264 potassium voltage-gated channel KQT-like protein 2 i... 614 e-175 gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H... 587 e-167 gi|26051268 potassium voltage-gated channel KQT-like protein 2 i... 472 e-133 gi|32479527 potassium voltage-gated channel, KQT-like subfamily,... 415 e-115 gi|32479525 potassium voltage-gated channel, KQT-like subfamily,... 386 e-107 gi|88758565 potassium voltage-gated channel, shaker-related subf... 90 8e-18 gi|27436974 potassium voltage-gated channel, Shab-related subfam... 89 1e-17 gi|24497464 Shaw-related voltage-gated potassium channel protein... 88 3e-17 gi|4826784 potassium voltage-gated channel, Shab-related subfami... 87 7e-17 gi|4504817 potassium voltage-gated channel, shaker-related subfa... 87 7e-17 gi|119395748 potassium voltage-gated channel subfamily A member ... 86 1e-16 gi|88758576 Shaw-related voltage-gated potassium channel protein... 86 2e-16 gi|24497462 Shaw-related voltage-gated potassium channel protein... 86 2e-16 gi|21217561 Shaw-related voltage-gated potassium channel protein... 84 5e-16 gi|21217563 Shaw-related voltage-gated potassium channel protein... 84 5e-16 gi|24497458 Shaw-related voltage-gated potassium channel protein... 84 5e-16 gi|24497460 Shaw-related voltage-gated potassium channel protein... 82 2e-15 gi|4826782 potassium voltage-gated channel, shaker-related subfa... 81 4e-15 gi|9789987 potassium voltage-gated channel, Shal-related subfami... 80 7e-15 gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 80 7e-15 >gi|236461719 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 2 [Homo sapiens] Length = 923 Score = 1827 bits (4733), Expect = 0.0 Identities = 923/923 (100%), Positives = 923/923 (100%) Query: 1 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL Sbjct: 1 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60 Query: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE Sbjct: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120 Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180 Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240 Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300 Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360 Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNQKLSFKERVRMAS 420 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNQKLSFKERVRMAS Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNQKLSFKERVRMAS 420 Query: 421 PRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID 480 PRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID Sbjct: 421 PRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID 480 Query: 481 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV 540 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV Sbjct: 481 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV 540 Query: 541 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKV 600 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKV Sbjct: 541 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKV 600 Query: 601 EKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGS 660 EKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGS Sbjct: 601 EKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGS 660 Query: 661 AQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAAT 720 AQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAAT Sbjct: 661 AQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQSDGSAVAAT 720 Query: 721 NTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNPAGLQESISDVTTCLVASKE 780 NTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNPAGLQESISDVTTCLVASKE Sbjct: 721 NTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNPAGLQESISDVTTCLVASKE 780 Query: 781 NVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSLSVQNLIRSTEELNIQLSGS 840 NVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSLSVQNLIRSTEELNIQLSGS Sbjct: 781 NVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSLSVQNLIRSTEELNIQLSGS 840 Query: 841 ESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAPQPAREAAFASDSLRTGRSR 900 ESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAPQPAREAAFASDSLRTGRSR Sbjct: 841 ESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAPQPAREAAFASDSLRTGRSR 900 Query: 901 SSQSICKAGESTDALSLPHVKLK 923 SSQSICKAGESTDALSLPHVKLK Sbjct: 901 SSQSICKAGESTDALSLPHVKLK 923 >gi|28373065 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 1 [Homo sapiens] Length = 932 Score = 1818 bits (4708), Expect = 0.0 Identities = 922/932 (98%), Positives = 923/932 (99%), Gaps = 9/932 (0%) Query: 1 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL Sbjct: 1 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60 Query: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE Sbjct: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120 Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180 Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240 Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300 Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360 Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT---------NQKLS 411 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT +QKLS Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSQKLS 420 Query: 412 FKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLK 471 FKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLK Sbjct: 421 FKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLK 480 Query: 472 SSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKET 531 SSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKET Sbjct: 481 SSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKET 540 Query: 532 LRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDL 591 LRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDL Sbjct: 541 LRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDL 600 Query: 592 SMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSP 651 SMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSP Sbjct: 601 SMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSP 660 Query: 652 VDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQ 711 VDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQ Sbjct: 661 VDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMHSQATQVPISQ 720 Query: 712 SDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNPAGLQESISDV 771 SDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNPAGLQESISDV Sbjct: 721 SDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNPAGLQESISDV 780 Query: 772 TTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSLSVQNLIRSTE 831 TTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSLSVQNLIRSTE Sbjct: 781 TTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSLSVQNLIRSTE 840 Query: 832 ELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAPQPAREAAFAS 891 ELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAPQPAREAAFAS Sbjct: 841 ELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAPQPAREAAFAS 900 Query: 892 DSLRTGRSRSSQSICKAGESTDALSLPHVKLK 923 DSLRTGRSRSSQSICKAGESTDALSLPHVKLK Sbjct: 901 DSLRTGRSRSSQSICKAGESTDALSLPHVKLK 932 >gi|236461942 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 3 [Homo sapiens] Length = 942 Score = 1816 bits (4703), Expect = 0.0 Identities = 923/942 (97%), Positives = 923/942 (97%), Gaps = 19/942 (2%) Query: 1 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL Sbjct: 1 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60 Query: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE Sbjct: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120 Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180 Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240 Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300 Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360 Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTN------------- 407 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTN Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNKFCSNKQKLFRMY 420 Query: 408 ------QKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR 461 QKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR Sbjct: 421 TSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFNDR 480 Query: 462 TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF 521 TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF Sbjct: 481 TRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKF 540 Query: 522 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI 581 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI Sbjct: 541 HVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKI 600 Query: 582 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE 641 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE Sbjct: 601 TAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFE 660 Query: 642 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH 701 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH Sbjct: 661 CEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYALSPTMH 720 Query: 702 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP 761 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP Sbjct: 721 SQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPETLHPNP 780 Query: 762 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL 821 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL Sbjct: 781 AGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKDLGKSL 840 Query: 822 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP 881 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP Sbjct: 841 SVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAP 900 Query: 882 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 923 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK Sbjct: 901 QPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 942 >gi|236462079 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 4 [Homo sapiens] Length = 951 Score = 1810 bits (4689), Expect = 0.0 Identities = 922/951 (96%), Positives = 923/951 (97%), Gaps = 28/951 (2%) Query: 1 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL Sbjct: 1 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60 Query: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE Sbjct: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120 Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180 Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240 Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300 Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360 Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT-------------- 406 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKEQGEASSSKFCS 420 Query: 407 --------------NQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKV 452 +QKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKV Sbjct: 421 NKQKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKV 480 Query: 453 QKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTV 512 QKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTV Sbjct: 481 QKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTV 540 Query: 513 IRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIT 572 IRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIT Sbjct: 541 IRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQIT 600 Query: 573 SDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALAL 632 SDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALAL Sbjct: 601 SDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALAL 660 Query: 633 ASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQT 692 ASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQT Sbjct: 661 ASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQT 720 Query: 693 FYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLP 752 FYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLP Sbjct: 721 FYALSPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLP 780 Query: 753 RPETLHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPM 812 RPETLHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPM Sbjct: 781 RPETLHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPM 840 Query: 813 VPKDLGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEET 872 VPKDLGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEET Sbjct: 841 VPKDLGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEET 900 Query: 873 ETDTFDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 923 ETDTFDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK Sbjct: 901 ETDTFDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 951 >gi|236462242 potassium voltage-gated channel, KQT-like subfamily, member 5 isoform 5 [Homo sapiens] Length = 822 Score = 819 bits (2116), Expect = 0.0 Identities = 406/409 (99%), Positives = 408/409 (99%) Query: 1 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL Sbjct: 1 MPRHHAGGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGRVLLNSAAARGDGLLL 60 Query: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE Sbjct: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLE 120 Query: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW Sbjct: 121 RPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIW 180 Query: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL Sbjct: 181 SAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQIL 240 Query: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD Sbjct: 241 RMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYAD 300 Query: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ Sbjct: 301 ALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQ 360 Query: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTNQK 409 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPT ++ Sbjct: 361 KHFEKRRNPAANLIQCVWRSYAADEKSVSIATWKPHLKALHTCSPTKKE 409 Score = 796 bits (2056), Expect = 0.0 Identities = 407/407 (100%), Positives = 407/407 (100%) Query: 517 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 576 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK Sbjct: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 475 Query: 577 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 636 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ Sbjct: 476 SREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQ 535 Query: 637 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 696 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL Sbjct: 536 IPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTPNEFSAQTFYAL 595 Query: 697 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 756 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET Sbjct: 596 SPTMHSQATQVPISQSDGSAVAATNTIANQINTAPKPAAPTTLQIPPPLPAIKHLPRPET 655 Query: 757 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 816 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD Sbjct: 656 LHPNPAGLQESISDVTTCLVASKENVQVAQSNLTKDRSMRKSFDMGGETLLSVCPMVPKD 715 Query: 817 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 876 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT Sbjct: 716 LGKSLSVQNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDT 775 Query: 877 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 923 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK Sbjct: 776 FDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK 822 >gi|26638655 potassium voltage-gated channel KQT-like protein 4 isoform b [Homo sapiens] Length = 641 Score = 762 bits (1967), Expect = 0.0 Identities = 408/627 (65%), Positives = 484/627 (77%), Gaps = 44/627 (7%) Query: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115 GGGG R R+ LLG PL S +S + +YRR+QN++ Sbjct: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87 Query: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175 YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+ Sbjct: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147 Query: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235 I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R Sbjct: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207 Query: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F Sbjct: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267 Query: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355 S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ Sbjct: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327 Query: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATWKPHLKALHTCSPTNQKLSFKE 414 EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW + L + S ++ K+ Sbjct: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFS---SRMGIKD 384 Query: 415 RVRMASPRGQSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLK 471 R+RM S + ++ S+Q A SPS++ E SPTKVQKSWSFNDRTRFR SLRL Sbjct: 385 RIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL- 443 Query: 472 SSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKET 531 KP A+ A +++V +EK QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKET Sbjct: 444 ----KPRTSAEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKET 498 Query: 532 LRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETT 588 LRPYDVKDVIEQYSAGHLDML RIKSLQTRVDQI+G+G D+K+RE K ++ E Sbjct: 499 LRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVV 556 Query: 589 DDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDY 648 D++SM+GRVVKVEKQVQSIE KLD LL Y + LR G+++ +L + Q+P F+ + TSDY Sbjct: 557 DEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDY 614 Query: 649 QSPVDSKDLSGSAQNSGCLSRSTSANI 675 SPVD +D+S SAQ +SRS S N+ Sbjct: 615 HSPVDHEDISVSAQTLS-ISRSVSTNM 640 >gi|26638653 potassium voltage-gated channel KQT-like protein 4 isoform a [Homo sapiens] Length = 695 Score = 746 bits (1926), Expect = 0.0 Identities = 409/678 (60%), Positives = 485/678 (71%), Gaps = 92/678 (13%) Query: 70 GGGGGLRESRRGKQGARMSLLGKPL--------------SYTSSQSCRRNVKYRRVQNYL 115 GGGG R R+ LLG PL S +S + +YRR+QN++ Sbjct: 37 GGGGSPR---------RLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWV 87 Query: 116 YNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEF 175 YNVLERPRGWAF+YH F+FLLVF CL+LSV STI EH +LA+ CLLILEFVMIVVFGLE+ Sbjct: 88 YNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEY 147 Query: 176 IIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLR 235 I+R+WSAGCCCRYRGWQGR RFARKPFCVID IV +AS+AV++A TQGNIFATSALRS+R Sbjct: 148 IVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMR 207 Query: 236 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDANKEF 295 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIF+SFLVYL EKDAN +F Sbjct: 208 FLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDF 267 Query: 296 STYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQ 355 S+YAD+LWWGTITLTTIGYGDKTP TWLGR+L+AGFALLGISFFALPAGILGSGFALKVQ Sbjct: 268 SSYADSLWWGTITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQ 327 Query: 356 EQHRQKHFEKRRNPAANLIQCVWRSYAAD-EKSVSIATW--------------------- 393 EQHRQKHFEKRR PAANLIQ WR Y+ D ++ ATW Sbjct: 328 EQHRQKHFEKRRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQ 387 Query: 394 ------------------------KPHLKALHT------CSPTNQKLSFKERVRMASPRG 423 P + H C + ++ K+R+RM S + Sbjct: 388 RARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQR 447 Query: 424 QSIKSRQ--ASVGDRRSPSTDITAEG-SPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVID 480 ++ S+Q A SPS++ E SPTKVQKSWSFNDRTRFR SLRL KP Sbjct: 448 RTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRL-----KPRTS 502 Query: 481 ADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDV 540 A+ A +++V +EK QC+++V+D+ P +KTVIR+IRI+KF VAKRKFKETLRPYDVKDV Sbjct: 503 AEDA-PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDV 561 Query: 541 IEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSRE---KITAEHETTDDLSMLGRV 597 IEQYSAGHLDML RIKSLQTRVDQI+G+G D+K+RE K ++ E D++SM+GRV Sbjct: 562 IEQYSAGHLDMLGRIKSLQTRVDQIVGRG--PGDRKAREKGDKGPSDAEVVDEISMMGRV 619 Query: 598 VKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDL 657 VKVEKQVQSIE KLD LL Y + LR G+++ +L + Q+P F+ + TSDY SPVD +D+ Sbjct: 620 VKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA--SLGAVQVPLFDPDITSDYHSPVDHEDI 677 Query: 658 SGSAQNSGCLSRSTSANI 675 S SAQ +SRS S N+ Sbjct: 678 SVSAQTLS-ISRSVSTNM 694 >gi|26051260 potassium voltage-gated channel KQT-like protein 2 isoform c [Homo sapiens] Length = 844 Score = 672 bits (1734), Expect = 0.0 Identities = 377/670 (56%), Positives = 456/670 (68%), Gaps = 63/670 (9%) Query: 52 AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111 + R LL+ G+ A G L + R G GA GKP +RN YR++ Sbjct: 34 STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77 Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171 QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K + L ILE V IVVF Sbjct: 78 QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137 Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231 G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197 Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291 RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257 Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351 N F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317 Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAAD-------------EKSVSIATWK--PH 396 LKVQEQHRQKHFEKRRNPAA LIQ WR YA + E++V++ ++ P Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYRLIPP 377 Query: 397 LKALHTC-------------------SPTNQKLSFKERVRMASPRGQSIKSRQASVGD-- 435 L L SP +QK+S K+RV +SPRG + K + + Sbjct: 378 LNQLELLRNLKSKSGLAFRKDPPPEPSP-SQKVSLKDRV-FSSPRGVAAKGKGSPQAQTV 435 Query: 436 RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKG 495 RRSPS D + E SP+KV KSWSF DR+R R + R+K + + + + +L +D+ D+K Sbjct: 436 RRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLPGEDIVDDKS 494 Query: 496 CQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRI 555 C C+ EDLTP LK IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RI Sbjct: 495 CPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRI 554 Query: 556 KSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLL 615 KSLQ+RVDQI+G+G +D K R K AE E +D SM+GR+ KVEKQV S+E KLD L+ Sbjct: 555 KSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLV 613 Query: 616 DIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANI 675 +IY Q R G A F E E Y SP DS++ GC+ + ++ Sbjct: 614 NIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSS 666 Query: 676 SRGLQFILTP 685 S G + P Sbjct: 667 STGQKNFSAP 676 >gi|26051262 potassium voltage-gated channel KQT-like protein 2 isoform b [Homo sapiens] Length = 854 Score = 668 bits (1723), Expect = 0.0 Identities = 375/679 (55%), Positives = 453/679 (66%), Gaps = 71/679 (10%) Query: 52 AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111 + R LL+ G+ A G L + R G GA GKP +RN YR++ Sbjct: 34 STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77 Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171 QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K + L ILE V IVVF Sbjct: 78 QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137 Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231 G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197 Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291 RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257 Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351 N F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317 Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAAD-------------EKSVSIATWKPHLK 398 LKVQEQHRQKHFEKRRNPAA LIQ WR YA + E++V++ + + Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377 Query: 399 ---ALHTCSPTN---------------------------QKLSFKERVRMASPRGQSIKS 428 A P N QK+S K+RV +SPRG + K Sbjct: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKG 436 Query: 429 RQASVGD--RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALG 486 + + RRSPS D + E SP+KV KSWSF DR+R R + R+K + + + + +L Sbjct: 437 KGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLP 495 Query: 487 TDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSA 546 +D+ D+K C C+ EDLTP LK IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSA Sbjct: 496 GEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSA 555 Query: 547 GHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQS 606 GHLDML RIKSLQ+RVDQI+G+G +D K R K AE E +D SM+GR+ KVEKQV S Sbjct: 556 GHLDMLSRIKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLS 614 Query: 607 IESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGC 666 +E KLD L++IY Q R G A F E E Y SP DS++ GC Sbjct: 615 MEKKLDFLVNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGC 667 Query: 667 LSRSTSANISRGLQFILTP 685 + + ++ S G + P Sbjct: 668 IVKIVRSSSSTGQKNFSAP 686 >gi|26051266 potassium voltage-gated channel KQT-like protein 2 isoform d [Homo sapiens] Length = 841 Score = 667 bits (1720), Expect = 0.0 Identities = 372/666 (55%), Positives = 451/666 (67%), Gaps = 58/666 (8%) Query: 52 AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111 + R LL+ G+ A G L + R G GA GKP +RN YR++ Sbjct: 34 STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77 Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171 QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K + L ILE V IVVF Sbjct: 78 QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137 Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231 G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197 Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291 RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257 Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351 N F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317 Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAAD-------------EKSVSIATWKPHLK 398 LKVQEQHRQKHFEKRRNPAA LIQ WR YA + E++V++ + + Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377 Query: 399 ---ALHTCSPTNQ---KLSFKERVRMA-----------SPRGQSIKSRQASVGD--RRSP 439 A P NQ + K + +A SPRG + K + + RRSP Sbjct: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSP 437 Query: 440 STDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCD 499 S D + E SP+KV KSWSF DR+R R + R+K + + +++ +L +D+ D+K C C+ Sbjct: 438 SADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQ--NSEASLPGEDIVDDKSCPCE 495 Query: 500 VSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQ 559 EDLTP LK IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ Sbjct: 496 FVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQ 555 Query: 560 TRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQ 619 +RVDQI+G+G +D K R K AE E +D SM+GR+ KVEKQV S+E KLD L++IY Sbjct: 556 SRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYM 614 Query: 620 QVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGL 679 Q R G A F E E Y SP DS++ GC+ + ++ S G Sbjct: 615 Q--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQ 667 Query: 680 QFILTP 685 + P Sbjct: 668 KNFSAP 673 >gi|26051264 potassium voltage-gated channel KQT-like protein 2 isoform a [Homo sapiens] Length = 872 Score = 614 bits (1583), Expect = e-175 Identities = 356/697 (51%), Positives = 437/697 (62%), Gaps = 89/697 (12%) Query: 52 AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111 + R LL+ G+ A G L + R G GA GKP +RN YR++ Sbjct: 34 STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77 Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171 QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K + L ILE V IVVF Sbjct: 78 QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137 Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231 G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197 Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291 RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257 Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351 N F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317 Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTNQKL 410 LKVQEQHRQKHFEKRRNPAA LIQ WR YA + + +TW+ + + + ++Q Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377 Query: 411 SFKERVRMASPRGQ-----SIKSRQASVGDRRSPSTDITAEGSPTK-------------- 451 ++ R+ P Q ++KS+ + P ++GSP + Sbjct: 378 TYGAS-RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSKGSPCRGPLCGCCPGRSSQK 436 Query: 452 --------------------------VQKSWSFNDRTRFRPS-----------------L 468 V++S S + PS Sbjct: 437 VSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAF 496 Query: 469 RLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKF 528 R+K + + + + G D + D+K C C+ EDLTP LK IRA+ +M+F V+KRKF Sbjct: 497 RIKGAASRQNSEEASLPGED-IVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKF 555 Query: 529 KETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETT 588 KE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQI+G+G +D K R K AE E Sbjct: 556 KESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELP 614 Query: 589 DDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDY 648 +D SM+GR+ KVEKQV S+E KLD L++IY Q R G A F E E Y Sbjct: 615 EDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPY 670 Query: 649 QSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTP 685 SP DS++ GC+ + ++ S G + P Sbjct: 671 HSPEDSRE---HVDRHGCIVKIVRSSSSTGQKNFSAP 704 >gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo sapiens] Length = 872 Score = 587 bits (1512), Expect = e-167 Identities = 337/664 (50%), Positives = 421/664 (63%), Gaps = 74/664 (11%) Query: 7 GGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGR------VLLNSAAARGDGLLL 60 GG +GG G G AA AGG +G ++ + G L A A DG LL Sbjct: 14 GGGDGGGGG-----GGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLL 68 Query: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGK-PLSYTSSQSCRRNVKYRRVQNYLYNVL 119 L GGG RR QG + LL K PLS R N KYRR+Q +Y+ L Sbjct: 69 L--------EGGGRDEGQRRTPQG--IGLLAKTPLSRPVK---RNNAKYRRIQTLIYDAL 115 Query: 120 ERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRI 179 ERPRGWA +YHA VFL+V GCLIL+V +T E+ ++ LL+LE I +FG EF +RI Sbjct: 116 ERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRI 175 Query: 180 WSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQI 239 W+AGCCCRY+GW+GRL+FARKP C++D VLIAS+ VV+ QGN+ ATS LRSLRFLQI Sbjct: 176 WAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS-LRSLRFLQI 234 Query: 240 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-------- 291 LRM+RMDRRGGTWKLLGS + AHSKELITAWYIGFL LI SSFLVYLVEKD Sbjct: 235 LRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGE 294 Query: 292 --NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSG 349 +EF TYADALWWG ITL TIGYGDKTP TW GRL++A F+L+G+SFFALPAGILGSG Sbjct: 295 EMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSG 354 Query: 350 FALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVS-IATWK--------PHLKAL 400 ALKVQEQHRQKHFEKRR PAA LIQ WR YA + + +ATW+ P + Sbjct: 355 LALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKE 414 Query: 401 HTCSPTNQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFND 460 + ++QKL +RVR+++PRG + K G +P E SP+K K N+ Sbjct: 415 QLEAASSQKLGLLDRVRLSNPRGSNTK------GKLFTPLNVDAIEESPSKEPKPVGLNN 468 Query: 461 RTRFRPSLRLKS-SQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIM 519 + RFR + R+K+ + + DA T D + +++G D +ED+ P LK IRA+RI+ Sbjct: 469 KERFRTAFRMKAYAFWQSSEDAGTG---DPMAEDRGYGNDFPIEDMIPTLKAAIRAVRIL 525 Query: 520 KFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSR- 578 +F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQTR+D I G ++ K + Sbjct: 526 QFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKS 585 Query: 579 ----------------EKITAEHETT--DDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQ 620 E A T+ +D SM+G+ VKVE+QVQ + KLD L+D++ Q Sbjct: 586 QKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQ 645 Query: 621 VLRK 624 + + Sbjct: 646 HMER 649 >gi|26051268 potassium voltage-gated channel KQT-like protein 2 isoform e [Homo sapiens] Length = 393 Score = 472 bits (1214), Expect = e-133 Identities = 238/344 (69%), Positives = 271/344 (78%), Gaps = 17/344 (4%) Query: 52 AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111 + R LL+ G+ A G L + R G GA GKP +RN YR++ Sbjct: 34 STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77 Query: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171 QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K + L ILE V IVVF Sbjct: 78 QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137 Query: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231 G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL Sbjct: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197 Query: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291 RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK Sbjct: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257 Query: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351 N F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA Sbjct: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317 Query: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWK 394 LKVQEQHRQKHFEKRRNPAA LIQ WR YA + + +TW+ Sbjct: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQ 361 >gi|32479527 potassium voltage-gated channel, KQT-like subfamily, member 1 isoform 1 [Homo sapiens] Length = 676 Score = 415 bits (1066), Expect = e-115 Identities = 239/540 (44%), Positives = 339/540 (62%), Gaps = 29/540 (5%) Query: 98 SSQSCRRNVKYR-RVQNYLYNVLERPRGW-AFIYHAFVFLLVFGCLILSVFSTIPEHTKL 155 S S RR V R VQ +YN LERP GW F+YH VFL+V CLI SV STI ++ L Sbjct: 92 SIYSTRRPVLARTHVQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAAL 151 Query: 156 ASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIA 215 A+ L +E V++V FG E+++R+WSAGC +Y G GRLRFARKP +ID IV++AS+ Sbjct: 152 ATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMV 211 Query: 216 VVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFL 275 V+ ++G +FATSA+R +RFLQILRM+ +DR+GGTW+LLGSVV+ H +ELIT YIGFL Sbjct: 212 VLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFL 271 Query: 276 VLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAG 330 LIFSS+ VYL EKDA EF +YADALWWG +T+TTIGYGDK P TW+G+ +++ Sbjct: 272 GLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASC 331 Query: 331 FALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI 390 F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++ AA+LIQ WR YAA+ S Sbjct: 332 FSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDSS- 390 Query: 391 ATWKPHLKAL---HTCSPTNQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEG 447 TWK +++ HT + K K+ V + + + K + G++ IT + Sbjct: 391 -TWKIYIRKAPRSHTLLSPSPKP--KKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDP 447 Query: 448 SPTKVQKSWS---FNDRTRFRPSLRLKSSQPKPVIDADTALGTDDVYDEKGCQCDVSVED 504 + +S ++ R P+L L+ S P + ++ D+ E + Sbjct: 448 PEERRLDHFSVDGYDSSVRKSPTL-LEVSMPH-FMRTNSFAEDLDLEGETLLTPITHISQ 505 Query: 505 LTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQ 564 L + I+ IR M++ VAK+KF++ +PYDV+DVIEQYS GHL+++ RIK LQ R+DQ Sbjct: 506 LREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQ 565 Query: 565 ILGKGQ--ITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVL 622 +GK I+ +KS+++ ++ R+ +VE +V ++ +L + D+ Q+L Sbjct: 566 SIGKPSLFISVSEKSKDR--------GSNTIGARLNRVEDKVTQLDQRLALITDMLHQLL 617 >gi|32479525 potassium voltage-gated channel, KQT-like subfamily, member 1 isoform 2 [Homo sapiens] Length = 549 Score = 386 bits (992), Expect = e-107 Identities = 219/502 (43%), Positives = 317/502 (63%), Gaps = 27/502 (5%) Query: 134 FLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQG 193 FL+V CLI SV STI ++ LA+ L +E V++V FG E+++R+WSAGC +Y G G Sbjct: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62 Query: 194 RLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWK 253 RLRFARKP +ID IV++AS+ V+ ++G +FATSA+R +RFLQILRM+ +DR+GGTW+ Sbjct: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122 Query: 254 LLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-----NKEFSTYADALWWGTIT 308 LLGSVV+ H +ELIT YIGFL LIFSS+ VYL EKDA EF +YADALWWG +T Sbjct: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182 Query: 309 LTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368 +TTIGYGDK P TW+G+ +++ F++ ISFFALPAGILGSGFALKVQ++ RQKHF ++ Sbjct: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242 Query: 369 PAANLIQCVWRSYAADEKSVSIATWKPHLKAL---HTCSPTNQKLSFKERVRMASPRGQS 425 AA+LIQ WR YAA+ S TWK +++ HT + K K+ V + + + Sbjct: 243 AAASLIQTAWRCYAAENPDSS--TWKIYIRKAPRSHTLLSPSPKP--KKSVVVKKKKFKL 298 Query: 426 IKSRQASVGDRRSPSTDITAEGSPTKVQKSWS---FNDRTRFRPSLRLKSSQPKPVIDAD 482 K + G++ IT + + +S ++ R P+L L+ S P + + Sbjct: 299 DKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL-LEVSMPH-FMRTN 356 Query: 483 TALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIE 542 + D+ E + L + I+ IR M++ VAK+KF++ +PYDV+DVIE Sbjct: 357 SFAEDLDLEGETLLTPITHISQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIE 416 Query: 543 QYSAGHLDMLCRIKSLQTRVDQILGKGQ--ITSDKKSREKITAEHETTDDLSMLGRVVKV 600 QYS GHL+++ RIK LQ R+DQ +GK I+ +KS+++ ++ R+ +V Sbjct: 417 QYSQGHLNLMVRIKELQRRLDQSIGKPSLFISVSEKSKDR--------GSNTIGARLNRV 468 Query: 601 EKQVQSIESKLDCLLDIYQQVL 622 E +V ++ +L + D+ Q+L Sbjct: 469 EDKVTQLDQRLALITDMLHQLL 490 >gi|88758565 potassium voltage-gated channel, shaker-related subfamily, member 3 [Homo sapiens] Length = 575 Score = 90.1 bits (222), Expect = 8e-18 Identities = 53/201 (26%), Positives = 103/201 (51%), Gaps = 16/201 (7%) Query: 157 SSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIA---S 213 S ++E + I+ F E ++R ++ + F+R +ID + +I + Sbjct: 292 SDPFFVVETLCIIWFSFELLVRFFAC---------PSKATFSRNIMNLIDIVAIIPYFIT 342 Query: 214 IAVVSAKTQGN---IFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITA 269 + A+ QGN + + LR +R +++ R+ ++ R ++LG + A +EL + Sbjct: 343 LGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLI 402 Query: 270 WYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSA 329 +++ V++FSS + + D FS+ DA WW +T+TT+GYGD P+T G+++ + Sbjct: 403 FFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGS 462 Query: 330 GFALLGISFFALPAGILGSGF 350 A+ G+ ALP ++ S F Sbjct: 463 LCAIAGVLTIALPVPVIVSNF 483 >gi|27436974 potassium voltage-gated channel, Shab-related subfamily, member 2 [Homo sapiens] Length = 911 Score = 89.4 bits (220), Expect = 1e-17 Identities = 88/354 (24%), Positives = 162/354 (45%), Gaps = 60/354 (16%) Query: 115 LYNVLERPRGWA---FIYHAFVFLLVFGCLILSVFSTIPEHTKLA-------SSCLLILE 164 L+++LE+P + + +V + LS+ +T+PE + + L +E Sbjct: 179 LWDLLEKPNSSVAAKILAIVSILFIVLSTIALSL-NTLPELQETDEFGQLNDNRQLAHVE 237 Query: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIAS-IAVVSAKTQG 223 V I F +E+++R S+ + +F + P VID + ++ + + ++ Sbjct: 238 AVCIAWFTMEYLLRFLSS---------PNKWKFFKGPLNVIDLLAILPYYVTIFLTESNK 288 Query: 224 NIFATSALRSL----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLI 278 ++ +R + R ++ILR++++ R + LG + EL + ++ ++I Sbjct: 289 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 348 Query: 279 FSSFLVYLVEKDANK-EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGIS 337 FSS LV+ EKD + +F++ + WW TIT+TT+GYGD P T LG+++ + G+ Sbjct: 349 FSS-LVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL 407 Query: 338 FFALPAGILGSGFALKVQEQHRQKHFEKRRNP-----------AANLIQCVWRSY----- 381 ALP I+ + F+ +EQ RQ+ KRR + NL RS Sbjct: 408 VIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARSMELIDV 467 Query: 382 -------------AADEKSVSIATWKPHLKALHTCSPTNQKLSFKERVRMASPR 422 +AD+ +S + WK KAL S T+ SF+ + + S + Sbjct: 468 AVEKAGESANTKDSADDNHLSPSRWKWARKAL---SETSSNKSFENKYQEVSQK 518 >gi|24497464 Shaw-related voltage-gated potassium channel protein 4 isoform b [Homo sapiens] Length = 582 Score = 88.2 bits (217), Expect = 3e-17 Identities = 75/285 (26%), Positives = 126/285 (44%), Gaps = 33/285 (11%) Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214 L +E V ++ F LEF++RI CC L F + +ID + ++ + Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAILPFYLEVGL 331 Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273 + +S+K ++ LR +RF++ILR+ ++ R ++LG + A + E L+ ++ Sbjct: 332 SGLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389 Query: 274 FLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITLTTIGYGDKTPLTWLG 324 VLIF++ + Y A + +F WW +T+TT+GYGD P TW G Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 449 Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQ-EQHRQKHFEKRRNPAANLIQCVWRSYAA 383 L+ A AL G+ A+P ++ + F + +QK +KR+ Q Y Sbjct: 450 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCK 509 Query: 384 DEKSVSIATWKPHLKALHTCSPTNQKLSFKERVRMASPRGQSIKS 428 E++ P SP ++ ER R RG KS Sbjct: 510 SEET------SPRDSTCSDTSPPAREEGMIERKRAGEIRGWEGKS 548 >gi|4826784 potassium voltage-gated channel, Shab-related subfamily, member 1 [Homo sapiens] Length = 858 Score = 87.0 bits (214), Expect = 7e-17 Identities = 72/270 (26%), Positives = 134/270 (49%), Gaps = 28/270 (10%) Query: 115 LYNVLERPRGWA---FIYHAFVFLLVFGCLILSVFSTIPEHTKLA-------SSCLLILE 164 L+++LE+P + + +V + LS+ +T+PE L + L +E Sbjct: 175 LWDLLEKPNSSVAAKILAIISIMFIVLSTIALSL-NTLPELQSLDEFGQSTDNPQLAHVE 233 Query: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIAS-IAVVSAKTQG 223 V I F +E+++R S+ + W +F + P ID + ++ + + ++ Sbjct: 234 AVCIAWFTMEYLLRFLSSP-----KKW----KFFKGPLNAIDLLAILPYYVTIFLTESNK 284 Query: 224 NIFATSALRSL----RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLI 278 ++ +R + R ++ILR++++ R + LG + EL + ++ ++I Sbjct: 285 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 344 Query: 279 FSSFLVYLVEKDANK-EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGIS 337 FSS LV+ EKD + +F + + WW TIT+TT+GYGD P T LG+++ + G+ Sbjct: 345 FSS-LVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVL 403 Query: 338 FFALPAGILGSGFALKVQEQHRQKHFEKRR 367 ALP I+ + F+ +EQ RQ+ KRR Sbjct: 404 VIALPIPIIVNNFSEFYKEQKRQEKAIKRR 433 >gi|4504817 potassium voltage-gated channel, shaker-related subfamily, member 4 [Homo sapiens] Length = 653 Score = 87.0 bits (214), Expect = 7e-17 Identities = 59/226 (26%), Positives = 105/226 (46%), Gaps = 23/226 (10%) Query: 162 ILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVS--- 218 I+E V IV F EF++R ++ + F + +ID + ++ + Sbjct: 373 IVETVCIVWFSFEFVVRCFAC---------PSQALFFKNIMNIIDIVSILPYFITLGTDL 423 Query: 219 AKTQGN-------IFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWY 271 A+ QG + + LR +R +++ R+ ++ R ++LG + A +EL + Sbjct: 424 AQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIF 483 Query: 272 IGFLVLIFSSFLVYLVEKDA-NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAG 330 F+ +I S VY E D F + DA WW +T+TT+GYGD P+T G+++ + Sbjct: 484 FLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSL 543 Query: 331 FALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAANLIQC 376 A+ G+ ALP ++ S F HR+ E++ N + C Sbjct: 544 CAIAGVLTIALPVPVIVSNFN---YFYHRETENEEQTQLTQNAVSC 586 >gi|119395748 potassium voltage-gated channel subfamily A member 1 [Homo sapiens] Length = 495 Score = 86.3 bits (212), Expect = 1e-16 Identities = 52/213 (24%), Positives = 108/213 (50%), Gaps = 18/213 (8%) Query: 147 STIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVID 206 +T+ ++ + + I+E + I+ F E ++R ++ + F + ID Sbjct: 208 TTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFAC---------PSKTDFFKNIMNFID 258 Query: 207 TIVLIA---SIAVVSAKTQGNIFATSA-----LRSLRFLQILRMVRMDRRGGTWKLLGSV 258 + +I ++ A+ +GN A LR +R +++ R+ ++ R ++LG Sbjct: 259 IVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQT 318 Query: 259 VYAHSKEL-ITAWYIGFLVLIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDK 317 + A +EL + +++ V++FSS + + ++A FS+ DA WW +++TT+GYGD Sbjct: 319 LKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDM 378 Query: 318 TPLTWLGRLLSAGFALLGISFFALPAGILGSGF 350 P+T G+++ + A+ G+ ALP ++ S F Sbjct: 379 YPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNF 411 >gi|88758576 Shaw-related voltage-gated potassium channel protein 4 isoform c [Homo sapiens] Length = 626 Score = 85.5 bits (210), Expect = 2e-16 Identities = 80/322 (24%), Positives = 135/322 (41%), Gaps = 36/322 (11%) Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214 L +E V ++ F LEF++RI CC L F + +ID + ++ + Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAILPFYLEVGL 331 Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273 + +S+K ++ LR +RF++ILR+ ++ R ++LG + A + E L+ ++ Sbjct: 332 SGLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389 Query: 274 FLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITLTTIGYGDKTPLTWLG 324 VLIF++ + Y A + +F WW +T+TT+GYGD P TW G Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 449 Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQ-EQHRQKHFEKRRNPAANLIQCVWRSYAA 383 L+ A AL G+ A+P ++ + F + +QK +KR+ Q Y Sbjct: 450 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCK 509 Query: 384 DEKSVSIATWKPHLKALHTCSPTNQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDI 443 E++ P SP ++ ER R S + A + D Sbjct: 510 SEET------SPRDSTCSDTSPPAREEGMIERKRADSKQN---GDANAVLSDEEGAGLTQ 560 Query: 444 TAEGSPTKVQKSWSFNDRTRFR 465 SPT ++ TR R Sbjct: 561 PLASSPTPEERRALRRSTTRDR 582 >gi|24497462 Shaw-related voltage-gated potassium channel protein 4 isoform a [Homo sapiens] Length = 635 Score = 85.5 bits (210), Expect = 2e-16 Identities = 80/322 (24%), Positives = 135/322 (41%), Gaps = 36/322 (11%) Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214 L +E V ++ F LEF++RI CC L F + +ID + ++ + Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCC-----PDTLDFVKNLLNIIDFVAILPFYLEVGL 331 Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273 + +S+K ++ LR +RF++ILR+ ++ R ++LG + A + E L+ ++ Sbjct: 332 SGLSSKAARDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 389 Query: 274 FLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITLTTIGYGDKTPLTWLG 324 VLIF++ + Y A + +F WW +T+TT+GYGD P TW G Sbjct: 390 LGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 449 Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQ-EQHRQKHFEKRRNPAANLIQCVWRSYAA 383 L+ A AL G+ A+P ++ + F + +QK +KR+ Q Y Sbjct: 450 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCK 509 Query: 384 DEKSVSIATWKPHLKALHTCSPTNQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDI 443 E++ P SP ++ ER R S + A + D Sbjct: 510 SEET------SPRDSTCSDTSPPAREEGMIERKRADSKQN---GDANAVLSDEEGAGLTQ 560 Query: 444 TAEGSPTKVQKSWSFNDRTRFR 465 SPT ++ TR R Sbjct: 561 PLASSPTPEERRALRRSTTRDR 582 >gi|21217561 Shaw-related voltage-gated potassium channel protein 2 isoform KV3.2a [Homo sapiens] Length = 613 Score = 84.3 bits (207), Expect = 5e-16 Identities = 69/283 (24%), Positives = 129/283 (45%), Gaps = 48/283 (16%) Query: 107 KYRRVQNYLYNVLERP---RGWAFIYHAFVFLLVFG----CL---------------ILS 144 ++RR+Q ++ + E P R FI A +F ++ CL +++ Sbjct: 207 RWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVIN 266 Query: 145 VFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV 204 S + ++ L +E V +V F EF++RI + +L F + + Sbjct: 267 GTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFS---------PNKLEFIKNLLNI 317 Query: 205 IDTIVLI-----ASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVV 259 ID + ++ ++ +S+K ++ LR +RF++ILR+ ++ R ++LG + Sbjct: 318 IDFVAILPFYLEVGLSGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 375 Query: 260 YAHSKE-LITAWYIGFLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITL 309 A + E L+ ++ VLIF++ + Y A + +F WW +T+ Sbjct: 376 RASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTM 435 Query: 310 TTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFAL 352 TT+GYGD P TW G L+ A AL G+ A+P ++ + F + Sbjct: 436 TTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478 >gi|21217563 Shaw-related voltage-gated potassium channel protein 2 isoform KV3.2b [Homo sapiens] Length = 638 Score = 84.3 bits (207), Expect = 5e-16 Identities = 69/283 (24%), Positives = 129/283 (45%), Gaps = 48/283 (16%) Query: 107 KYRRVQNYLYNVLERP---RGWAFIYHAFVFLLVFG----CL---------------ILS 144 ++RR+Q ++ + E P R FI A +F ++ CL +++ Sbjct: 207 RWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVIN 266 Query: 145 VFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV 204 S + ++ L +E V +V F EF++RI + +L F + + Sbjct: 267 GTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFS---------PNKLEFIKNLLNI 317 Query: 205 IDTIVLI-----ASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVV 259 ID + ++ ++ +S+K ++ LR +RF++ILR+ ++ R ++LG + Sbjct: 318 IDFVAILPFYLEVGLSGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 375 Query: 260 YAHSKE-LITAWYIGFLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITL 309 A + E L+ ++ VLIF++ + Y A + +F WW +T+ Sbjct: 376 RASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTM 435 Query: 310 TTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFAL 352 TT+GYGD P TW G L+ A AL G+ A+P ++ + F + Sbjct: 436 TTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478 >gi|24497458 Shaw-related voltage-gated potassium channel protein 2 isoform KV3.2c [Homo sapiens] Length = 558 Score = 84.3 bits (207), Expect = 5e-16 Identities = 69/283 (24%), Positives = 129/283 (45%), Gaps = 48/283 (16%) Query: 107 KYRRVQNYLYNVLERP---RGWAFIYHAFVFLLVFG----CL---------------ILS 144 ++RR+Q ++ + E P R FI A +F ++ CL +++ Sbjct: 207 RWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVIN 266 Query: 145 VFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCV 204 S + ++ L +E V +V F EF++RI + +L F + + Sbjct: 267 GTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFS---------PNKLEFIKNLLNI 317 Query: 205 IDTIVLI-----ASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVV 259 ID + ++ ++ +S+K ++ LR +RF++ILR+ ++ R ++LG + Sbjct: 318 IDFVAILPFYLEVGLSGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTL 375 Query: 260 YAHSKE-LITAWYIGFLVLIFSSFLVYLVEKDA---------NKEFSTYADALWWGTITL 309 A + E L+ ++ VLIF++ + Y A + +F WW +T+ Sbjct: 376 RASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTM 435 Query: 310 TTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFAL 352 TT+GYGD P TW G L+ A AL G+ A+P ++ + F + Sbjct: 436 TTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478 >gi|24497460 Shaw-related voltage-gated potassium channel protein 3 [Homo sapiens] Length = 757 Score = 82.0 bits (201), Expect = 2e-15 Identities = 57/224 (25%), Positives = 106/224 (47%), Gaps = 26/224 (11%) Query: 160 LLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLI-----ASI 214 L +E V +V F EF++RI ++ F + +ID + ++ + Sbjct: 348 LTYVEGVCVVWFTFEFLMRITFC---------PDKVEFLKSSLNIIDCVAILPFYLEVGL 398 Query: 215 AVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKE-LITAWYIG 273 + +S+K ++ LR +RF++ILR+ ++ R ++LG + A + E L+ ++ Sbjct: 399 SGLSSKAAKDVLGF--LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLA 456 Query: 274 FLVLIFSSFLVYLVEKDANKE---------FSTYADALWWGTITLTTIGYGDKTPLTWLG 324 VLIF++ + Y A+ + F WW +T+TT+GYGD P TW G Sbjct: 457 LGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSG 516 Query: 325 RLLSAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRN 368 L+ A AL G+ A+P ++ + F + ++ K++N Sbjct: 517 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKN 560 >gi|4826782 potassium voltage-gated channel, shaker-related subfamily, member 2 [Homo sapiens] Length = 499 Score = 81.3 bits (199), Expect = 4e-15 Identities = 51/199 (25%), Positives = 95/199 (47%), Gaps = 19/199 (9%) Query: 162 ILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKT 221 I+E + I+ F EF++R ++ + F +ID + +I + + Sbjct: 224 IVETLCIIWFSFEFLVRFFAC---------PSKAGFFTNIMNIIDIVAIIPYFITLGTEL 274 Query: 222 --------QGN-IFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYI 272 QG + + LR +R +++ R+ ++ R ++LG + A +EL + Sbjct: 275 AEKPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFF 334 Query: 273 GFLVLIFSSFLVYLVEKDANK-EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGF 331 F+ +I S VY E D + +F + DA WW +++TT+GYGD P T G+++ + Sbjct: 335 LFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLC 394 Query: 332 ALLGISFFALPAGILGSGF 350 A+ G+ ALP ++ S F Sbjct: 395 AIAGVLTIALPVPVIVSNF 413 >gi|9789987 potassium voltage-gated channel, Shal-related subfamily, member 2 [Homo sapiens] Length = 630 Score = 80.5 bits (197), Expect = 7e-15 Identities = 59/254 (23%), Positives = 116/254 (45%), Gaps = 31/254 (12%) Query: 131 AFVFLLVFGCLI-LSVFSTIPEHTKLASS---------------CLLILEFVMIVVFGLE 174 A VF V G I +SV + + E SS L+ +++F +E Sbjct: 184 ALVFYYVTGFFIAVSVIANVVETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVE 243 Query: 175 FIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSL 234 +++R+ +A R RF R +ID + ++ + N + A +L Sbjct: 244 YLLRLAAA---------PSRYRFVRSVMSIIDVVAILPYY--IGLVMTDNEDVSGAFVTL 292 Query: 235 RFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLVLIFSSFLVYLVEKDANK 293 R ++ R+ + R ++LG + + + EL + + ++IF++ + Y + + Sbjct: 293 RVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSAS 352 Query: 294 EFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFALK 353 +F++ A W+ +T+TT+GYGD P T G++ + +L G+ ALP ++ S F+ Sbjct: 353 KFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFS-- 410 Query: 354 VQEQHRQKHFEKRR 367 + H+ + +KRR Sbjct: 411 -RIYHQNQRADKRR 423 >gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] Length = 500 Score = 80.5 bits (197), Expect = 7e-15 Identities = 69/255 (27%), Positives = 117/255 (45%), Gaps = 28/255 (10%) Query: 111 VQNYLYNVLERP------RGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILE 164 V+ L+N+LE+P R + I FV + + ++S E + L L ILE Sbjct: 192 VRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSA-----ELSWLDLQLLEILE 246 Query: 165 FVMIVVFGLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGN 224 +V I F EF++R C R R RF RK +ID + ++ + ++ Sbjct: 247 YVCISWFTGEFVLRF----LCVR-----DRCRFLRKVPNIIDLLAILPFYITLLVESLSG 297 Query: 225 IFATSALRS-------LRFLQILRMVRMDRRGGTWKLLGSVVYAHSKEL-ITAWYIGFLV 276 T L + LR L+ LRM+++ R + LG + +E+ + ++ + Sbjct: 298 SQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGI 357 Query: 277 LIFSSFLVYLVEKDANKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGI 336 IFS+ + + + F++ A WW T ++TT+GYGD P T G++++ L GI Sbjct: 358 SIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGI 417 Query: 337 SFFALPAGILGSGFA 351 ALP I+ F+ Sbjct: 418 LVLALPIAIINDRFS 432 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,266,587 Number of Sequences: 37866 Number of extensions: 1600545 Number of successful extensions: 8771 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 109 Number of HSP's successfully gapped in prelim test: 108 Number of HSP's that attempted gapping in prelim test: 8036 Number of HSP's gapped (non-prelim): 656 length of query: 923 length of database: 18,247,518 effective HSP length: 112 effective length of query: 811 effective length of database: 14,006,526 effective search space: 11359292586 effective search space used: 11359292586 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.