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Search of human proteins with 23397576
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23397576 bestrophin 4 [Homo sapiens]
(473 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23397576 bestrophin 4 [Homo sapiens] 950 0.0
gi|119703742 vitelliform macular dystrophy 2-like 1 [Homo sapiens] 517 e-147
gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1 [H... 481 e-136
gi|4759310 bestrophin 1 isoform 1 [Homo sapiens] 459 e-129
gi|212720889 bestrophin 1 isoform 2 [Homo sapiens] 390 e-108
gi|115527106 vitelliform macular dystrophy 2-like 3 isoform 2 [H... 111 2e-24
gi|38093637 Nance-Horan syndrome protein isoform 1 [Homo sapiens] 35 0.11
gi|194239668 SHC (Src homology 2 domain containing) transforming... 33 0.56
gi|194239664 SHC (Src homology 2 domain containing) transforming... 33 0.56
gi|194239662 SHC (Src homology 2 domain containing) transforming... 33 0.56
gi|32261324 SHC (Src homology 2 domain containing) transforming ... 33 0.56
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 31 2.8
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 31 2.8
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 31 2.8
gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain... 30 3.6
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens] 30 3.6
gi|50345881 cytoplasmic polyadenylation element binding protein ... 30 4.8
gi|124378039 SEC16 homolog A [Homo sapiens] 30 4.8
gi|239752693 PREDICTED: similar to hCG2041787 [Homo sapiens] 30 4.8
gi|239747227 PREDICTED: similar to hCG2041787 [Homo sapiens] 30 4.8
gi|239741035 PREDICTED: similar to hCG2041787 [Homo sapiens] 30 4.8
gi|209413756 synapsin III isoform IIIg [Homo sapiens] 30 4.8
gi|209413752 synapsin III isoform IIIa [Homo sapiens] 30 4.8
gi|40807443 protein regulator of cytokinesis 1 isoform 2 [Homo s... 30 4.8
gi|4506039 protein regulator of cytokinesis 1 isoform 1 [Homo sa... 30 4.8
gi|4557625 glutamate-cysteine ligase, catalytic subunit [Homo sa... 29 8.1
gi|71043876 undifferentiated embryonic cell transcription factor... 29 8.1
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 29 8.1
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens] 29 8.1
gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens] 29 8.1
>gi|23397576 bestrophin 4 [Homo sapiens]
Length = 473
Score = 950 bits (2455), Expect = 0.0
Identities = 473/473 (100%), Positives = 473/473 (100%)
Query: 1 MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRY 60
MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRY
Sbjct: 1 MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRY 60
Query: 61 VYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQR 120
VYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQR
Sbjct: 61 VYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQR 120
Query: 121 GRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNK 180
GRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNK
Sbjct: 121 GRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNK 180
Query: 181 YWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVV 240
YWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVV
Sbjct: 181 YWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVV 240
Query: 241 TIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYA 300
TIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYA
Sbjct: 241 TIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYA 300
Query: 301 GWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQP 360
GWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQP
Sbjct: 301 GWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQP 360
Query: 361 PYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGVGA 420
PYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGVGA
Sbjct: 361 PYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGVGA 420
Query: 421 PSPAISLRNFGRVRGTPRPPHLLRFRAEEGGDPEAAARIEEESAESGDEALEP 473
PSPAISLRNFGRVRGTPRPPHLLRFRAEEGGDPEAAARIEEESAESGDEALEP
Sbjct: 421 PSPAISLRNFGRVRGTPRPPHLLRFRAEEGGDPEAAARIEEESAESGDEALEP 473
>gi|119703742 vitelliform macular dystrophy 2-like 1 [Homo sapiens]
Length = 509
Score = 517 bits (1332), Expect = e-147
Identities = 258/420 (61%), Positives = 314/420 (74%), Gaps = 18/420 (4%)
Query: 1 MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRY 60
MTV+YT +VA ARFGGFS LLL WRGSIYKLL++E L F Y LS YR +LT+ Q+
Sbjct: 1 MTVTYTARVANARFGGFSQLLLLWRGSIYKLLWRELLCFLGFYMALSAAYRFVLTEGQKR 60
Query: 61 VYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQR 120
+ ++ YC++ A LIP+SFVLGFYVTLVVNRWWSQY +PLPD LMCV++ +VHG D R
Sbjct: 61 YFEKLVIYCDQYASLIPVSFVLGFYVTLVVNRWWSQYLCMPLPDALMCVVAGTVHGRDDR 120
Query: 121 GRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNK 180
GRL RRTL+RYA L++VL+LRSVST V KRFPT++HVV+AGFM++EERKKFE+L S +NK
Sbjct: 121 GRLYRRTLMRYAGLSAVLILRSVSTAVFKRFPTIDHVVEAGFMTREERKKFENLNSSYNK 180
Query: 181 YWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVV 240
YWVPCVWF+NLAAQARR+GRIRD+ AL LLLEELN +R KC MLFHYDWIS+PLVYTQVV
Sbjct: 181 YWVPCVWFSNLAAQARREGRIRDNSALKLLLEELNVFRGKCGMLFHYDWISVPLVYTQVV 240
Query: 241 TIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYA 300
TIA+YS+F L+GRQF++P G D D+ VP+ TLLQFFFYA
Sbjct: 241 TIALYSYFLACLIGRQFLDPAQGYKD---------------HDLDLCVPIFTLLQFFFYA 285
Query: 301 GWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQP 360
GWLKVAEQ+INPFGEDDDDFETN LIDRN QVS+L+VDEMY +L EKD YWD + +
Sbjct: 286 GWLKVAEQLINPFGEDDDDFETNFLIDRNFQVSMLAVDEMYDDLAVLEKDLYWDAAEARA 345
Query: 361 PYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGVGA 420
PYT AT + +PSF GSTF++ ++ ++ +Q + G P A L R L GA
Sbjct: 346 PYTAATVFQLRQPSFQGSTFDITLA---KEDMQFQRLDGLDGPMGEAPGDFLQRLLPAGA 402
>gi|115527104 vitelliform macular dystrophy 2-like 3 isoform 1 [Homo
sapiens]
Length = 668
Score = 481 bits (1239), Expect = e-136
Identities = 237/392 (60%), Positives = 300/392 (76%), Gaps = 18/392 (4%)
Query: 1 MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRY 60
MTV+Y+ KVA A F GF LLL+WRGSIYKLLY+EF++F LY +S+ YRLLLT Q+
Sbjct: 1 MTVTYSSKVANATFFGFHRLLLKWRGSIYKLLYREFIVFAVLYTAISLVYRLLLTGVQKR 60
Query: 61 VYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQR 120
+ +++ YC+R A+ IP++FVLGFYVTLVVNRWW+Q+ ++P PD+LM +IS+SVHG D+
Sbjct: 61 YFEKLSIYCDRYAEQIPVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEH 120
Query: 121 GRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNK 180
GRLLRRTL+RY NL S+L+ RSVST V KRFPTM+HVV+AGFM+ +ERK F LKS K
Sbjct: 121 GRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLK 180
Query: 181 YWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVV 240
YWVP +WF NLA +AR +GRIRD + L L+ E+N+YR+ CS+LF YDW+ IPLVYTQVV
Sbjct: 181 YWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFGYDWVGIPLVYTQVV 240
Query: 241 TIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYA 300
T+AVY+FF L+GRQF++P G A D D+Y+P+ TLLQFFFYA
Sbjct: 241 TLAVYTFFFACLIGRQFLDPTKGYAG---------------HDLDLYIPIFTLLQFFFYA 285
Query: 301 GWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQP 360
GWLKVAEQ+INPFGEDDDDFETN IDRNLQVSLL+VDEM+ +LP +KD YWD+ +P
Sbjct: 286 GWLKVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARP 345
Query: 361 PYTVATAAESLRPSFLGSTFNLRM--SDDPEQ 390
PYT+A AA+ PSFLGST + + SD P++
Sbjct: 346 PYTLA-AADYCIPSFLGSTVQMGLSGSDFPDE 376
>gi|4759310 bestrophin 1 isoform 1 [Homo sapiens]
Length = 585
Score = 459 bits (1182), Expect = e-129
Identities = 235/418 (56%), Positives = 295/418 (70%), Gaps = 22/418 (5%)
Query: 1 MTVSYTLKVAEARFGGFSGLLLRWRGSIYKLLYKEFLLFGALYAVLSITYRLLLTQEQRY 60
MT++YT +VA AR G FS LLL WRGSIYKLLY EFL+F Y ++ YRL LT+EQ+
Sbjct: 1 MTITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQL 60
Query: 61 VYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQR 120
++ ++ YC+ LIP+SFVLGFYVTLVV RWW+QY ++P PD+LM ++S V G D++
Sbjct: 61 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 120
Query: 121 GRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNK 180
GRLLRRTLIRYANL +VL+LRSVST V KRFP+ +H+V AGFM+ E K+ E L N
Sbjct: 121 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 180
Query: 181 YWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVV 240
+WVP VWF NL+ +A GRIRD I L LL E+N R +C L+ YDWISIPLVYTQVV
Sbjct: 181 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 240
Query: 241 TIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYA 300
T+AVYSFF LVGRQF+ P PG E D+ VP+ T LQFFFY
Sbjct: 241 TVAVYSFFLTCLVGRQFLNPAKA--------YPGHE-------LDLVVPVFTFLQFFFYV 285
Query: 301 GWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQP 360
GWLKVAEQ+INPFGEDDDDFETN ++DRNLQVSLL+VDEM+Q+LP E D YW++ +PQP
Sbjct: 286 GWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQP 345
Query: 361 PYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGV 418
PYT A +A+ R SF+GSTFN+ ++ + ++E P A ++GRFLG+
Sbjct: 346 PYT-AASAQFRRASFMGSTFNISLNKE-----EMEFQPNQ-EDEEDAHAGIIGRFLGL 396
>gi|212720889 bestrophin 1 isoform 2 [Homo sapiens]
Length = 604
Score = 390 bits (1001), Expect = e-108
Identities = 199/358 (55%), Positives = 251/358 (70%), Gaps = 22/358 (6%)
Query: 61 VYAQVARYCNRSADLIPLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQR 120
++ ++ YC+ LIP+SFVLGFYVTLVV RWW+QY ++P PD+LM ++S V G D++
Sbjct: 1 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ 60
Query: 121 GRLLRRTLIRYANLASVLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNK 180
GRLLRRTLIRYANL +VL+LRSVST V KRFP+ +H+V AGFM+ E K+ E L N
Sbjct: 61 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM 120
Query: 181 YWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCSMLFHYDWISIPLVYTQVV 240
+WVP VWF NL+ +A GRIRD I L LL E+N R +C L+ YDWISIPLVYTQVV
Sbjct: 121 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV 180
Query: 241 TIAVYSFFALSLVGRQFVEPEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYA 300
T+AVYSFF LVGRQF+ P PG E D+ VP+ T LQFFFY
Sbjct: 181 TVAVYSFFLTCLVGRQFLNPAKA--------YPGHE-------LDLVVPVFTFLQFFFYV 225
Query: 301 GWLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQP 360
GWLKVAEQ+INPFGEDDDDFETN ++DRNLQVSLL+VDEM+Q+LP E D YW++ +PQP
Sbjct: 226 GWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQP 285
Query: 361 PYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGV 418
PYT A +A+ R SF+GSTFN+ ++ + ++E P A ++GRFLG+
Sbjct: 286 PYT-AASAQFRRASFMGSTFNISLNKE-----EMEFQPNQ-EDEEDAHAGIIGRFLGL 336
>gi|115527106 vitelliform macular dystrophy 2-like 3 isoform 2 [Homo
sapiens]
Length = 455
Score = 111 bits (277), Expect = 2e-24
Identities = 56/91 (61%), Positives = 71/91 (78%), Gaps = 3/91 (3%)
Query: 302 WLKVAEQIINPFGEDDDDFETNQLIDRNLQVSLLSVDEMYQNLPPAEKDQYWDEDQPQPP 361
+ +VAEQ+INPFGEDDDDFETN IDRNLQVSLL+VDEM+ +LP +KD YWD+ +PP
Sbjct: 74 YTQVAEQLINPFGEDDDDFETNWCIDRNLQVSLLAVDEMHMSLPKMKKDIYWDDSAARPP 133
Query: 362 YTVATAAESLRPSFLGSTFNLRM--SDDPEQ 390
YT+A AA+ PSFLGST + + SD P++
Sbjct: 134 YTLA-AADYCIPSFLGSTVQMGLSGSDFPDE 163
Score = 103 bits (256), Expect = 4e-22
Identities = 47/85 (55%), Positives = 60/85 (70%)
Query: 163 MSQEERKKFESLKSDFNKYWVPCVWFTNLAAQARRDGRIRDDIALCLLLEELNKYRAKCS 222
M+ +ERK F LKS KYWVP +WF NLA +AR +GRIRD + L L+ E+N+YR+ CS
Sbjct: 1 MTTDERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCS 60
Query: 223 MLFHYDWISIPLVYTQVVTIAVYSF 247
+LF YDW+ IPLVYTQV + F
Sbjct: 61 LLFGYDWVGIPLVYTQVAEQLINPF 85
>gi|38093637 Nance-Horan syndrome protein isoform 1 [Homo sapiens]
Length = 1630
Score = 35.4 bits (80), Expect = 0.11
Identities = 25/80 (31%), Positives = 31/80 (38%)
Query: 388 PEQSLQVEASPGSGRPAPAAQTPLLGRFLGVGAPSPAISLRNFGRVRGTPRPPHLLRFRA 447
P V+AS GS P P Q P V AP P R G P PP L A
Sbjct: 19 PAPGPAVDASGGSAEPPPPLQPPGRRDLDEVEAPGPEEPARAVPAPSGLPPPPPPLPAPA 78
Query: 448 EEGGDPEAAARIEEESAESG 467
++ P A + E + +G
Sbjct: 79 DQTQPPHGEASVAGEESTAG 98
>gi|194239668 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 4 [Homo sapiens]
Length = 473
Score = 33.1 bits (74), Expect = 0.56
Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 10/71 (14%)
Query: 353 WDEDQPQPPYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRP-APAAQTPL 411
WDE++ +PP + LG ++R+ + A+PG+ RP AP AQTP
Sbjct: 227 WDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREG--------AAPGAARPTAPNAQTPS 278
Query: 412 -LGRFLGVGAP 421
LG L VG P
Sbjct: 279 HLGATLPVGQP 289
>gi|194239664 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 3 [Homo sapiens]
Length = 584
Score = 33.1 bits (74), Expect = 0.56
Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 10/71 (14%)
Query: 353 WDEDQPQPPYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRP-APAAQTPL 411
WDE++ +PP + LG ++R+ + A+PG+ RP AP AQTP
Sbjct: 337 WDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREG--------AAPGAARPTAPNAQTPS 388
Query: 412 -LGRFLGVGAP 421
LG L VG P
Sbjct: 389 HLGATLPVGQP 399
>gi|194239662 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 1 [Homo sapiens]
Length = 583
Score = 33.1 bits (74), Expect = 0.56
Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 10/71 (14%)
Query: 353 WDEDQPQPPYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRP-APAAQTPL 411
WDE++ +PP + LG ++R+ + A+PG+ RP AP AQTP
Sbjct: 337 WDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREG--------AAPGAARPTAPNAQTPS 388
Query: 412 -LGRFLGVGAP 421
LG L VG P
Sbjct: 389 HLGATLPVGQP 399
>gi|32261324 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 2 [Homo sapiens]
Length = 474
Score = 33.1 bits (74), Expect = 0.56
Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 10/71 (14%)
Query: 353 WDEDQPQPPYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRP-APAAQTPL 411
WDE++ +PP + LG ++R+ + A+PG+ RP AP AQTP
Sbjct: 227 WDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREG--------AAPGAARPTAPNAQTPS 278
Query: 412 -LGRFLGVGAP 421
LG L VG P
Sbjct: 279 HLGATLPVGQP 289
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 30.8 bits (68), Expect = 2.8
Identities = 40/148 (27%), Positives = 51/148 (34%), Gaps = 34/148 (22%)
Query: 358 PQPPYTVATA-AES---LRPSFL------GSTFNLRMSDDPEQSLQVEAS-PGSGRPAPA 406
PQPP + A ES LR +FL G+ + + P Q QV A+ PGSG P PA
Sbjct: 489 PQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPA 548
Query: 407 A-----------------------QTPLLGRFLGVGAPSPAISLRNFGRVRGTPRPPHLL 443
TP GA + A G P PHLL
Sbjct: 549 GGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLL 608
Query: 444 RFRAEEGGDPEAAARIEEESAESGDEAL 471
R GG ++ + E+L
Sbjct: 609 EGRKAGGGSYHHSSAFRPVGGKDDAESL 636
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 30.8 bits (68), Expect = 2.8
Identities = 40/148 (27%), Positives = 51/148 (34%), Gaps = 34/148 (22%)
Query: 358 PQPPYTVATA-AES---LRPSFL------GSTFNLRMSDDPEQSLQVEAS-PGSGRPAPA 406
PQPP + A ES LR +FL G+ + + P Q QV A+ PGSG P PA
Sbjct: 489 PQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPA 548
Query: 407 A-----------------------QTPLLGRFLGVGAPSPAISLRNFGRVRGTPRPPHLL 443
TP GA + A G P PHLL
Sbjct: 549 GGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLL 608
Query: 444 RFRAEEGGDPEAAARIEEESAESGDEAL 471
R GG ++ + E+L
Sbjct: 609 EGRKAGGGSYHHSSAFRPVGGKDDAESL 636
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 30.8 bits (68), Expect = 2.8
Identities = 40/148 (27%), Positives = 51/148 (34%), Gaps = 34/148 (22%)
Query: 358 PQPPYTVATA-AES---LRPSFL------GSTFNLRMSDDPEQSLQVEAS-PGSGRPAPA 406
PQPP + A ES LR +FL G+ + + P Q QV A+ PGSG P PA
Sbjct: 489 PQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPA 548
Query: 407 A-----------------------QTPLLGRFLGVGAPSPAISLRNFGRVRGTPRPPHLL 443
TP GA + A G P PHLL
Sbjct: 549 GGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLL 608
Query: 444 RFRAEEGGDPEAAARIEEESAESGDEAL 471
R GG ++ + E+L
Sbjct: 609 EGRKAGGGSYHHSSAFRPVGGKDDAESL 636
>gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain and
proline-rich containing [Homo sapiens]
Length = 1435
Score = 30.4 bits (67), Expect = 3.6
Identities = 40/156 (25%), Positives = 59/156 (37%), Gaps = 27/156 (17%)
Query: 333 SLLSVDEMYQNLPPAEKDQYWDEDQPQP-------------PYTVATAAESLRPSFLGST 379
SLL E+ P EK++ ++D P P+ + A E+ L +
Sbjct: 917 SLLEPGELEGLFFPEEKEEEKEKDDSPPQKWPELSHGLHLVPFIHSAAEEAEPEPELAA- 975
Query: 380 FNLRMSDDPEQSLQVEASPGS-GRPAPAAQTPLLGRFLGVGAPSPAISLRNFGRVRGTPR 438
P + + +A P + G P+PAA P G + P LR+ R R PR
Sbjct: 976 --------PGEDAEPQAGPSARGSPSPAAPGPPAGPLPRMDLPLAGQPLRHPTRARPRPR 1027
Query: 439 PPHLLRFRAEEGGDPEAAARIEEESAESG--DEALE 472
H R GG A +E + S DE +E
Sbjct: 1028 RQH--HHRPPPGGPQVPPALPQEGNGLSARVDEGVE 1061
>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
Length = 2303
Score = 30.4 bits (67), Expect = 3.6
Identities = 34/131 (25%), Positives = 52/131 (39%), Gaps = 23/131 (17%)
Query: 345 PPAEKDQYWDEDQPQPPYTVATAAESLRPSFLGSTFNLRMSDDP-------EQSLQVEAS 397
PPA D+ P Y+++++A SL S+ P E ++ +
Sbjct: 1560 PPARTQPSLIADETPPCYSLSSSASSLSEP--------EPSEPPAVHPRGREPAVTKDPG 1611
Query: 398 PGSGR---PAPAAQTPLLGRFLGVGAP--SPAISLRNFGRVRGT---PRPPHLLRFRAEE 449
PG GR P+P A LL R + P P +S + R T RP R R EE
Sbjct: 1612 PGGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGSRERGEE 1671
Query: 450 GGDPEAAARIE 460
+ A+ ++
Sbjct: 1672 AAGSDRASDLD 1682
>gi|50345881 cytoplasmic polyadenylation element binding protein 3
[Homo sapiens]
Length = 698
Score = 30.0 bits (66), Expect = 4.8
Identities = 34/118 (28%), Positives = 47/118 (39%), Gaps = 11/118 (9%)
Query: 357 QPQPPYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSG----RPAPAAQTPLL 412
QP PP A SL PSF GST++ ++ E S +P +G + P P+
Sbjct: 89 QPPPPQEPAAPGASLSPSF-GSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVF 147
Query: 413 GRFLGVGAPSPAISLRNFGRVRGTPRPPHLLRFRAEEGGDPEAAARIEEESAESGDEA 470
G G SP I L + P PP A+ P+A + S S +A
Sbjct: 148 G-----GTFSPQIGLAQ-TQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQA 199
>gi|124378039 SEC16 homolog A [Homo sapiens]
Length = 2357
Score = 30.0 bits (66), Expect = 4.8
Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 17/87 (19%)
Query: 388 PEQSLQVEASPGSGR----PAPAAQTPLLGRFLGVGAP------------SPAISLRNFG 431
P + L ++ S S + P P P G GAP S + S R+ G
Sbjct: 472 PSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTGAPDATLHTVHPDSVSSSYSSRSHG 531
Query: 432 RVRGTPRPPHLL-RFRAEEGGDPEAAA 457
R+ G+ RP L+ F +E G PE A
Sbjct: 532 RLSGSARPQELVGTFIQQEVGKPEDEA 558
>gi|239752693 PREDICTED: similar to hCG2041787 [Homo sapiens]
Length = 269
Score = 30.0 bits (66), Expect = 4.8
Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 381 NLRMSDDPEQSLQVEASPGSGR-PAPAAQTPLLGRFLGVGAPSPAISLRNFGRVRGTPRP 439
++ +S+ P E++P + R PA A+ PL R G+G P + R GTP
Sbjct: 97 SVSVSEAPSPEGAGESAPSADRGPATLARAPL--RRAGIGCPEGPVGFRRPRATPGTPEA 154
Query: 440 P 440
P
Sbjct: 155 P 155
>gi|239747227 PREDICTED: similar to hCG2041787 [Homo sapiens]
Length = 183
Score = 30.0 bits (66), Expect = 4.8
Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 381 NLRMSDDPEQSLQVEASPGSGR-PAPAAQTPLLGRFLGVGAPSPAISLRNFGRVRGTPRP 439
++ +S+ P E++P + R PA A+ PL R G+G P + R GTP
Sbjct: 11 SVSVSEAPSPEGAGESAPSADRGPATLARAPL--RRAGIGCPEGPVGFRRPRATPGTPEA 68
Query: 440 P 440
P
Sbjct: 69 P 69
>gi|239741035 PREDICTED: similar to hCG2041787 [Homo sapiens]
Length = 269
Score = 30.0 bits (66), Expect = 4.8
Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 381 NLRMSDDPEQSLQVEASPGSGR-PAPAAQTPLLGRFLGVGAPSPAISLRNFGRVRGTPRP 439
++ +S+ P E++P + R PA A+ PL R G+G P + R GTP
Sbjct: 97 SVSVSEAPSPEGAGESAPSADRGPATLARAPL--RRAGIGCPEGPVGFRRPRATPGTPEA 154
Query: 440 P 440
P
Sbjct: 155 P 155
>gi|209413756 synapsin III isoform IIIg [Homo sapiens]
Length = 579
Score = 30.0 bits (66), Expect = 4.8
Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 11/106 (10%)
Query: 357 QPQP---PYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAP--AAQTPL 411
QPQP P A+S +P GS R+S +Q L SP SG P + +P
Sbjct: 430 QPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPL----SPQSGSPQQQRSPGSPQ 485
Query: 412 LGRFLGVGAPSPAISLRNFGRVRGTPRPPHLLRFRAEEGGDPEAAA 457
L R +P+ A + + PRPP R +++G + + A
Sbjct: 486 LSRASSGSSPNQA--SKPGATLASQPRPPVQGRSTSQQGEESKKPA 529
>gi|209413752 synapsin III isoform IIIa [Homo sapiens]
Length = 580
Score = 30.0 bits (66), Expect = 4.8
Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 11/106 (10%)
Query: 357 QPQP---PYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAP--AAQTPL 411
QPQP P A+S +P GS R+S +Q L SP SG P + +P
Sbjct: 431 QPQPRPPPQGGPRQAQSPQPQRSGSPSQQRLSPQGQQPL----SPQSGSPQQQRSPGSPQ 486
Query: 412 LGRFLGVGAPSPAISLRNFGRVRGTPRPPHLLRFRAEEGGDPEAAA 457
L R +P+ A + + PRPP R +++G + + A
Sbjct: 487 LSRASSGSSPNQA--SKPGATLASQPRPPVQGRSTSQQGEESKKPA 530
>gi|40807443 protein regulator of cytokinesis 1 isoform 2 [Homo
sapiens]
Length = 606
Score = 30.0 bits (66), Expect = 4.8
Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 9/75 (12%)
Query: 365 ATAAESLRPSFLGSTFNLRMSD-DPEQSLQVEASPGSGRPAPAA--------QTPLLGRF 415
ATA S+RP F G+ ++ +S P S V AS SG+ P L G
Sbjct: 496 ATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSI 555
Query: 416 LGVGAPSPAISLRNF 430
L G P A RNF
Sbjct: 556 LSGGYPGSAPLQRNF 570
>gi|4506039 protein regulator of cytokinesis 1 isoform 1 [Homo
sapiens]
Length = 620
Score = 30.0 bits (66), Expect = 4.8
Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 9/75 (12%)
Query: 365 ATAAESLRPSFLGSTFNLRMSD-DPEQSLQVEASPGSGRPAPAA--------QTPLLGRF 415
ATA S+RP F G+ ++ +S P S V AS SG+ P L G
Sbjct: 496 ATANSSIRPIFGGTVYHSPVSRLPPSGSKPVAASTCSGKKTPRTGRHGANKENLELNGSI 555
Query: 416 LGVGAPSPAISLRNF 430
L G P A RNF
Sbjct: 556 LSGGYPGSAPLQRNF 570
>gi|4557625 glutamate-cysteine ligase, catalytic subunit [Homo
sapiens]
Length = 637
Score = 29.3 bits (64), Expect = 8.1
Identities = 18/62 (29%), Positives = 28/62 (45%)
Query: 32 LYKEFLLFGALYAVLSITYRLLLTQEQRYVYAQVARYCNRSADLIPLSFVLGFYVTLVVN 91
+Y + + FG L +T++ E RY+Y Q+A C L S YV+ +
Sbjct: 236 IYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDC 295
Query: 92 RW 93
RW
Sbjct: 296 RW 297
>gi|71043876 undifferentiated embryonic cell transcription factor 1
[Homo sapiens]
Length = 341
Score = 29.3 bits (64), Expect = 8.1
Identities = 29/100 (29%), Positives = 35/100 (35%), Gaps = 11/100 (11%)
Query: 358 PQPPYTVATAAESLRPSFLGSTFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLG 417
P P AT + R T+ LR S P +S +PGS PAPA L
Sbjct: 178 PAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGS-PPAPAPTA------LA 230
Query: 418 VGAPSPAISLRNFGRVRGTPRPPHLLRFRAEEGGDPEAAA 457
P +R G+P PP G PE A
Sbjct: 231 TCIPEDRAPVRG----PGSPPPPPAREDPDSPPGRPEDCA 266
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 29.3 bits (64), Expect = 8.1
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 383 RMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGVGAPSPAISLRNFG--RVRGTPRPP 440
R+S DP + VEAS GSG P L R L P ++ G +G+ PP
Sbjct: 863 RLSRDPRLTRHVEASGGSGPGDSGPSDPRLARALPTSKPEGSLHSSPVGPSSSKGSGPPP 922
>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
Length = 916
Score = 29.3 bits (64), Expect = 8.1
Identities = 22/55 (40%), Positives = 27/55 (49%), Gaps = 9/55 (16%)
Query: 257 FVEPEAG---AAKPQKLLKPGQEPAPALGDPDMYVPLTT-----LLQFFFYAGWL 303
F+ PE+G A KP LL+PGQ P LG P T+ LL + GWL
Sbjct: 136 FLRPESGSLPALKPLPLLRPGQAKTP-LGVPMSGTGTTSSAPLALLPLDSFEGWL 189
>gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens]
Length = 1603
Score = 29.3 bits (64), Expect = 8.1
Identities = 54/219 (24%), Positives = 77/219 (35%), Gaps = 26/219 (11%)
Query: 260 PEAGAAKPQKLLKPGQEPAPALGDPDMYVPLTTLLQFFFYAGWLKVAEQIINPFGEDDDD 319
PEA + Q L P EP P L DP L+ A L + + +P G
Sbjct: 254 PEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLA 313
Query: 320 FETNQLIDRNLQVSLLSVDEMYQNLPPAEK--DQYWDEDQPQPPYTVATAAESLRPSFLG 377
+ + +L+ LL Q L P K D +PQ P AE LR
Sbjct: 314 LQALDTLPDSLESQLLDP----QALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCS 369
Query: 378 ----------STFNLRMSDDPEQSLQVEASPGSGRPAPAAQTPLLGRFLGVGAPSPAISL 427
+ LR +D P + L G GR A A GR L + P+ ++
Sbjct: 370 PHGPPGPEGHPKYALRRTDRP-KILCRRRKAGRGRKADAGPE---GRLLPLPMPTGLVAA 425
Query: 428 RNFGRVRGTPRPPHLLRFRAEEGGDPEAAARIEEESAES 466
P PP L G P + ++ ES+++
Sbjct: 426 LAEPPPPPPPPPPAL------PGPGPVSVPELKPESSQT 458
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,642,072
Number of Sequences: 37866
Number of extensions: 920227
Number of successful extensions: 3087
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 3067
Number of HSP's gapped (non-prelim): 38
length of query: 473
length of database: 18,247,518
effective HSP length: 106
effective length of query: 367
effective length of database: 14,233,722
effective search space: 5223775974
effective search space used: 5223775974
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.