Guide to the Human Genome
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Name: GCLC Sequence: fasta or formatted (637aa) NCBI GI: 4557625
Description:

glutamate-cysteine ligase, catalytic subunit

Referenced in:

Glutathione Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0         32           2
 C cysteine            2.2         14           2
 D aspartate           6.3         40           2
 E glutamate           8.0         51           2
 F phenylalanine       4.2         27           2
 G glycine             5.7         36           2
 H histidine           2.7         17           1
 I isoleucine          6.3         40           2
 K lysine              6.3         40           2
 L leucine             8.8         56           2
 M methionine          2.8         18           1
 N asparagine          5.2         33           3
 P proline             4.9         31           4
 Q glutamine           3.0         19           1
 R arginine            5.8         37           2
 S serine              7.1         45           2
 T threonine           5.0         32           1
 V valine              6.0         38           2
 W tryptophan          1.1          7           1
 Y tyrosine            3.8         24           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   glutamate-cysteine ligase, catalytic subunit 
MICAL2                0.005   microtubule associated monoxygenase, calponin and LIM...
FBXL13                0.004   F-box and leucine-rich repeat protein 13 isoform 2 ...
FBXL13                0.004   F-box and leucine-rich repeat protein 13 isoform 1 ...
ZBED4                 0.004   zinc finger, BED-type containing 4 
TTC37                 0.004   tetratricopeptide repeat domain 37 
KIAA0564              0.004   hypothetical protein LOC23078 isoform a 
KIAA0564              0.004   hypothetical protein LOC23078 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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