Search of human proteins with 23110932

Search of human proteins with 23110932

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23110932 proteasome beta 9 subunit isoform 2 proprotein
[Homo sapiens]
         (209 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo...   416   e-117
gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo ...   412   e-116
gi|23110925 proteasome beta 6 subunit [Homo sapiens]                  265   2e-71
gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]        98   6e-21
gi|73747875 proteasome beta 8 subunit isoform E2 proprotein [Hom...    97   7e-21
gi|4758970 proteasome beta 8 subunit isoform E1 proprotein [Homo...    97   7e-21
gi|4506203 proteasome beta 7 subunit proprotein [Homo sapiens]         92   3e-19
gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens]          90   1e-18
gi|153791216 proteasome beta 11 subunit [Homo sapiens]                 85   4e-17
gi|195539356 proteasome beta 5 subunit isoform 2 [Homo sapiens]        65   5e-11
gi|22538465 proteasome beta 3 subunit [Homo sapiens]                   64   9e-11
gi|222144262 proteasome beta 5 subunit isoform 3 [Homo sapiens]        62   3e-10
gi|4506193 proteasome beta 1 subunit [Homo sapiens]                    47   2e-05
gi|4506195 proteasome beta 2 subunit [Homo sapiens]                    44   1e-04
gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens]        41   8e-04
gi|23110942 proteasome alpha 5 subunit [Homo sapiens]                  41   8e-04
gi|22538467 proteasome beta 4 subunit [Homo sapiens]                   40   0.002
gi|4506189 proteasome alpha 7 subunit [Homo sapiens]                   38   0.005
gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens]       35   0.035
gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens]         35   0.035
gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens]        34   0.078
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]                 31   0.86 
gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens]        29   2.5  
gi|145580600 schlafen family member 5 [Homo sapiens]                   28   5.6  
gi|23110944 proteasome alpha 6 subunit [Homo sapiens]                  28   7.3  
gi|239753084 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]         28   7.3  
gi|239749701 PREDICTED: hypothetical protein XP_002347123 [Homo ...    28   7.3  
gi|88952907 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]          28   7.3  
gi|239743967 PREDICTED: hypothetical protein XP_002344251 [Homo ...    28   7.3  
gi|88943925 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]          28   7.3  

>gi|23110932 proteasome beta 9 subunit isoform 2 proprotein [Homo
           sapiens]
          Length = 209

 Score =  416 bits (1069), Expect = e-117
 Identities = 209/209 (100%), Positives = 209/209 (100%)

Query: 1   MLRAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAA 60
           MLRAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAA
Sbjct: 1   MLRAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAA 60

Query: 61  DAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQ 120
           DAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQ
Sbjct: 61  DAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQ 120

Query: 121 VYGTLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSG 180
           VYGTLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSG
Sbjct: 121 VYGTLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSG 180

Query: 181 GVIYLVTITAAGVDHRVILGNELPKFYDE 209
           GVIYLVTITAAGVDHRVILGNELPKFYDE
Sbjct: 181 GVIYLVTITAAGVDHRVILGNELPKFYDE 209


>gi|4506205 proteasome beta 9 subunit isoform 1 proprotein [Homo
           sapiens]
          Length = 219

 Score =  412 bits (1060), Expect = e-116
 Identities = 207/207 (100%), Positives = 207/207 (100%)

Query: 3   RAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADA 62
           RAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADA
Sbjct: 13  RAGEVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADA 72

Query: 63  QAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVY 122
           QAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVY
Sbjct: 73  QAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVY 132

Query: 123 GTLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGV 182
           GTLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGV
Sbjct: 133 GTLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGV 192

Query: 183 IYLVTITAAGVDHRVILGNELPKFYDE 209
           IYLVTITAAGVDHRVILGNELPKFYDE
Sbjct: 193 IYLVTITAAGVDHRVILGNELPKFYDE 219


>gi|23110925 proteasome beta 6 subunit [Homo sapiens]
          Length = 239

 Score =  265 bits (677), Expect = 2e-71
 Identities = 126/202 (62%), Positives = 160/202 (79%), Gaps = 1/202 (0%)

Query: 6   EVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAV 65
           EV TGTTIMAV+FDGGVV+G+DSR + G  + NRV DKL+P+H+RI+C  SGSAAD QAV
Sbjct: 30  EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAV 89

Query: 66  ADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGT- 124
           AD   YQL  H IEL EPPLV  AA++ + + Y+YREDL A +++AGWD +EGGQVY   
Sbjct: 90  ADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVP 149

Query: 125 LGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIY 184
           +GGM+ RQ FAIGGSGS++IYGYVDA Y+ GM+ EEC +FT +A+ALAM RDGSSGGVI 
Sbjct: 150 MGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIR 209

Query: 185 LVTITAAGVDHRVILGNELPKF 206
           L  I  +GV+ +V+LG+++PKF
Sbjct: 210 LAAIAESGVERQVLLGDQIPKF 231


>gi|4506191 proteasome beta 10 subunit proprotein [Homo sapiens]
          Length = 273

 Score = 97.8 bits (242), Expect = 6e-21
 Identities = 57/185 (30%), Positives = 93/185 (50%), Gaps = 2/185 (1%)

Query: 9   TGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADM 68
           TGTTI  + F  GV++G+D+R +    V ++  +K+  +  +IYC  +G AADA+    M
Sbjct: 38  TGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRM 97

Query: 69  AAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGT-LGG 127
            A ++ELH +     P V     ++R   ++Y+  + A L+V G D   G Q+YG    G
Sbjct: 98  VASKMELHALSTGREPRVATVTRILRQTLFRYQGHVGASLIVGGVD-LTGPQLYGVHPHG 156

Query: 128 MLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVT 187
             +R PF   GSG       ++  ++P M+ E  +    +A+   +  D  SGG +    
Sbjct: 157 SYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACV 216

Query: 188 ITAAG 192
           IT  G
Sbjct: 217 ITKTG 221


>gi|73747875 proteasome beta 8 subunit isoform E2 proprotein [Homo
           sapiens]
          Length = 276

 Score = 97.4 bits (241), Expect = 7e-21
 Identities = 62/179 (34%), Positives = 92/179 (51%), Gaps = 1/179 (0%)

Query: 6   EVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAV 65
           E+  GTT +A +F  GV+   DSR SAG  +     +K+  ++  +   +SG AAD Q  
Sbjct: 68  EMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYW 127

Query: 66  ADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYRE-DLSAHLMVAGWDQREGGQVYGT 124
             + A +  L+ +   E   V AA+ ++ N+  +YR   LS   M+ GWD++  G  Y  
Sbjct: 128 ERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVD 187

Query: 125 LGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVI 183
             G          GSG+T+ YG +D+ Y+P +SPEE       AIA A  RD  SGGV+
Sbjct: 188 EHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVV 246


>gi|4758970 proteasome beta 8 subunit isoform E1 proprotein [Homo
           sapiens]
          Length = 272

 Score = 97.4 bits (241), Expect = 7e-21
 Identities = 62/179 (34%), Positives = 92/179 (51%), Gaps = 1/179 (0%)

Query: 6   EVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAV 65
           E+  GTT +A +F  GV+   DSR SAG  +     +K+  ++  +   +SG AAD Q  
Sbjct: 64  EMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYW 123

Query: 66  ADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYRE-DLSAHLMVAGWDQREGGQVYGT 124
             + A +  L+ +   E   V AA+ ++ N+  +YR   LS   M+ GWD++  G  Y  
Sbjct: 124 ERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVD 183

Query: 125 LGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVI 183
             G          GSG+T+ YG +D+ Y+P +SPEE       AIA A  RD  SGGV+
Sbjct: 184 EHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVV 242


>gi|4506203 proteasome beta 7 subunit proprotein [Homo sapiens]
          Length = 277

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 55/187 (29%), Positives = 93/187 (49%), Gaps = 2/187 (1%)

Query: 9   TGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADM 68
           TGTTI  V +  G+V+G+D+R + G  V ++   K+  +   IYC  +G+AAD      +
Sbjct: 42  TGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQL 101

Query: 69  AAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGTL-GG 127
            +  LELH +     P V+ A  +++ + ++Y+  + A L++ G D   G  +Y     G
Sbjct: 102 ISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQGYIGAALVLGGVDV-TGPHLYSIYPHG 160

Query: 128 MLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVT 187
              + P+   GSGS       +  ++P M  EE +   ++AIA  +  D  SG  I L  
Sbjct: 161 STDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCV 220

Query: 188 ITAAGVD 194
           I+   +D
Sbjct: 221 ISKNKLD 227


>gi|4506201 proteasome beta 5 subunit isoform 1 [Homo sapiens]
          Length = 263

 Score = 90.1 bits (222), Expect = 1e-18
 Identities = 57/189 (30%), Positives = 97/189 (51%), Gaps = 3/189 (1%)

Query: 6   EVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAV 65
           E+  GTT +A +F  GV++ +DSR +AG  + ++   K+  ++  +   ++G AAD    
Sbjct: 55  EMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFW 114

Query: 66  ADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVY-G 123
             + A Q  ++ +  +E   V AA+ ++ N+ Y+Y+   LS   M+ GWD+R  G  Y  
Sbjct: 115 ERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVD 174

Query: 124 TLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVI 183
           + G  ++   F++ GSGS + YG +D  Y   +  E+       AI  A  RD  SGG +
Sbjct: 175 SEGNRISGATFSV-GSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAV 233

Query: 184 YLVTITAAG 192
            L  +   G
Sbjct: 234 NLYHVREDG 242


>gi|153791216 proteasome beta 11 subunit [Homo sapiens]
          Length = 300

 Score = 85.1 bits (209), Expect = 4e-17
 Identities = 59/189 (31%), Positives = 93/189 (49%), Gaps = 5/189 (2%)

Query: 10  GTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMA 69
           GTT +A  F  GV+  +D+R S G  V      K+ P+H+ +    SG++AD      + 
Sbjct: 49  GTTTLAFRFRHGVIAAADTRSSCGSYVACPASCKVIPVHQHLLGTTSGTSADCATWYRVL 108

Query: 70  AYQLELHGIELEEPPLVLAAANVVRNISYKYRE-DLSAHLMVAGWDQREGGQVYGTL--G 126
             +L L  +   + P V +AA ++  +  +YR  DL     + GWD R G +++     G
Sbjct: 109 QRELRLRELREGQLPSVASAAKLLSAMMSQYRGLDLCVATALCGWD-RSGPELFYVYSDG 167

Query: 127 GMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLV 186
             L    F++ GSGS + YG +D  Y+  MS +E       A+A A  RD  SGG + L 
Sbjct: 168 TRLQGDIFSV-GSGSPYAYGVLDRGYRYDMSTQEAYALARCAVAHATHRDAYSGGSVDLF 226

Query: 187 TITAAGVDH 195
            +  +G +H
Sbjct: 227 HVRESGWEH 235


>gi|195539356 proteasome beta 5 subunit isoform 2 [Homo sapiens]
          Length = 160

 Score = 64.7 bits (156), Expect = 5e-11
 Identities = 43/140 (30%), Positives = 69/140 (49%), Gaps = 3/140 (2%)

Query: 55  LSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYRE-DLSAHLMVAGW 113
           ++G AAD      + A Q  ++ +  +E   V AA+ ++ N+ Y+Y+   LS   M+ GW
Sbjct: 1   MAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGW 60

Query: 114 DQREGGQVY-GTLGGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALA 172
           D+R  G  Y  + G  ++   F++G SGS + YG +D  Y   +  E+       AI  A
Sbjct: 61  DKRGPGLYYVDSEGNRISGATFSVG-SGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQA 119

Query: 173 MSRDGSSGGVIYLVTITAAG 192
             RD  SGG + L  +   G
Sbjct: 120 TYRDAYSGGAVNLYHVREDG 139


>gi|22538465 proteasome beta 3 subunit [Homo sapiens]
          Length = 205

 Score = 63.9 bits (154), Expect = 9e-11
 Identities = 46/181 (25%), Positives = 84/181 (46%), Gaps = 5/181 (2%)

Query: 8   HTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVAD 67
           + G  +MA++    V + +D R      +V   F K+ P+ +R+Y  L+G A D Q VA 
Sbjct: 6   YNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQ 65

Query: 68  MAAYQLELHGIELEEPPLVLAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVYGTL- 125
              ++L L+ ++           ++V N+ Y+ R        ++AG D +       +L 
Sbjct: 66  RLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLD 125

Query: 126 --GGMLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSG-GV 182
             G  +    F + G+ +  +YG  ++ ++P M P+      + A+  A+ RD  SG GV
Sbjct: 126 LIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGV 185

Query: 183 I 183
           I
Sbjct: 186 I 186


>gi|222144262 proteasome beta 5 subunit isoform 3 [Homo sapiens]
          Length = 203

 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 38/133 (28%), Positives = 71/133 (53%), Gaps = 7/133 (5%)

Query: 6   EVHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAV 65
           E+  GTT +A +F  GV++ +DSR +AG  + ++   K+  ++  +   ++G AAD    
Sbjct: 55  EMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFW 114

Query: 66  ADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVYGT 124
             + A Q  ++ +  +E   V AA+ ++ N+ Y+Y+   LS   M+ GWD+R      G 
Sbjct: 115 ERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR------GP 168

Query: 125 LGGMLTRQPFAIG 137
           +  +L  +P + G
Sbjct: 169 VSEVLCLKPKSFG 181


>gi|4506193 proteasome beta 1 subunit [Homo sapiens]
          Length = 241

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 45/203 (22%), Positives = 80/203 (39%), Gaps = 11/203 (5%)

Query: 7   VHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVA 66
           V  G TI+A+  +   ++ SD+R+S G ++  R   K   L ++     SG   D   + 
Sbjct: 34  VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 93

Query: 67  DMAAYQLELHGIELEEPPLVLAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVYG-T 124
            +   +L+++     +     A A ++  I Y  R      + ++ G D+   G VY   
Sbjct: 94  KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 153

Query: 125 LGGMLTRQPFAIGGSGSTFIYGYVD--AAYK-------PGMSPEECRRFTTDAIALAMSR 175
             G   R  F  GGS S  +   +D    +K         +S +   R   D    A  R
Sbjct: 154 PVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAER 213

Query: 176 DGSSGGVIYLVTITAAGVDHRVI 198
           D  +G  + +  +T  G+    +
Sbjct: 214 DVYTGDALRICIVTKEGIREETV 236


>gi|4506195 proteasome beta 2 subunit [Homo sapiens]
          Length = 201

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 39/142 (27%), Positives = 64/142 (45%), Gaps = 5/142 (3%)

Query: 23  VMGSDSRVSAGEAV-VNRVFDKLSPLHERIYCALSGSAADAQAVADMAAYQLELHGIELE 81
           V+ +  RV+A   V +    DK+  + E+I     G A D    A+     ++L+ +   
Sbjct: 13  VLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNG 72

Query: 82  EPPLVLAAANVV-RNIS--YKYREDLSAHLMVAGWDQREGGQV-YGTLGGMLTRQPFAIG 137
                 AAAN   RN++   + R     +L++AG+D+ EG  + Y      L + PFA  
Sbjct: 73  YELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAH 132

Query: 138 GSGSTFIYGYVDAAYKPGMSPE 159
           G G+      +D  Y P +S E
Sbjct: 133 GYGAFLTLSILDRYYTPTISRE 154


>gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens]
          Length = 250

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 6/123 (4%)

Query: 7   VHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVA 66
           V  G+T + +     VV+G + + S  +    R   K+  L + +  A +G  ADA+ V 
Sbjct: 28  VKKGSTAVGIRGTNIVVLGVEKK-SVAKLQDERTVRKICALDDHVCMAFAGLTADARVVI 86

Query: 67  DMAAYQLELHGIELEEPPLVLAAANVVRNISYKY-----REDLSAHLMVAGWDQREGGQV 121
           + A  + + H + +E+P  V      +  +  KY     R       ++ G+D     ++
Sbjct: 87  NRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDDDGISRL 146

Query: 122 YGT 124
           Y T
Sbjct: 147 YQT 149


>gi|23110942 proteasome alpha 5 subunit [Homo sapiens]
          Length = 241

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 22/97 (22%), Positives = 48/97 (49%), Gaps = 1/97 (1%)

Query: 7   VHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVA 66
           +  G+T + ++   GV +  + R+++     + + +K+  +   I CA+SG  ADA+ + 
Sbjct: 31  IKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSI-EKIVEIDAHIGCAMSGLIADAKTLI 89

Query: 67  DMAAYQLELHGIELEEPPLVLAAANVVRNISYKYRED 103
           D A  + + H     E   V +    V N++ ++ E+
Sbjct: 90  DKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEE 126


>gi|22538467 proteasome beta 4 subunit [Homo sapiens]
          Length = 264

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 43/194 (22%), Positives = 76/194 (39%), Gaps = 10/194 (5%)

Query: 9   TGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADM 68
           TGT+++ V+F+GGVV+ +D   S G     R   ++  ++       SG  AD Q +  +
Sbjct: 52  TGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQV 111

Query: 69  AAYQL---ELHGIELEEPPLVLAAANVVRNISYKYREDLSA---HLMVAGWDQREGGQVY 122
               +   EL G      P   A  + +    Y  R  ++     +++ G+   E    Y
Sbjct: 112 LGQMVIDEELLGDGHSYSP--RAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGY 169

Query: 123 GTLGGMLTRQPFAIGGSGSTFIYGYVDAAY--KPGMSPEECRRFTTDAIALAMSRDGSSG 180
             + G+    P    G G+      +      +P +S  E R      + +   RD  S 
Sbjct: 170 VDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSY 229

Query: 181 GVIYLVTITAAGVD 194
               + T+T  GV+
Sbjct: 230 NRFQIATVTEKGVE 243


>gi|4506189 proteasome alpha 7 subunit [Homo sapiens]
          Length = 248

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 28/123 (22%), Positives = 54/123 (43%), Gaps = 6/123 (4%)

Query: 7   VHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVA 66
           V  G+T + V     VV+G + + S  +    R   K+  L + +  A +G  ADA+ V 
Sbjct: 26  VKKGSTAVGVRGRDIVVLGVEKK-SVAKLQDERTVRKICALDDNVCMAFAGLTADARIVI 84

Query: 67  DMAAYQLELHGIELEEPPLVLAAANVVRNISYKY-----REDLSAHLMVAGWDQREGGQV 121
           + A  + + H + +E+P  V      + ++  +Y     R       ++ G+D     ++
Sbjct: 85  NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144

Query: 122 YGT 124
           Y T
Sbjct: 145 YQT 147


>gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
          Length = 261

 Score = 35.4 bits (80), Expect = 0.035
 Identities = 29/132 (21%), Positives = 61/132 (46%), Gaps = 15/132 (11%)

Query: 8   HTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVF--DKLSPLHERIYCALSGSAADAQAV 65
           H GT +  +  DG ++      +     +++ VF  +K+  L+E + C+++G  +DA  +
Sbjct: 30  HAGTCLGILANDGVLLAAERRNI---HKLLDEVFFSEKIYKLNEDMACSVAGITSDANVL 86

Query: 66  ADMAAYQLELHGIELEEP----PLVLAAANVVRNIS-YKYREDLSAHLMVAGWDQREGGQ 120
            +      + + ++ +EP     LV A  ++ +  + +  +      L+  GWD+  G Q
Sbjct: 87  TNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQ 146

Query: 121 VY-----GTLGG 127
           +Y     G  GG
Sbjct: 147 LYQSDPSGNYGG 158


>gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
          Length = 261

 Score = 35.4 bits (80), Expect = 0.035
 Identities = 29/132 (21%), Positives = 61/132 (46%), Gaps = 15/132 (11%)

Query: 8   HTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVF--DKLSPLHERIYCALSGSAADAQAV 65
           H GT +  +  DG ++      +     +++ VF  +K+  L+E + C+++G  +DA  +
Sbjct: 30  HAGTCLGILANDGVLLAAERRNI---HKLLDEVFFSEKIYKLNEDMACSVAGITSDANVL 86

Query: 66  ADMAAYQLELHGIELEEP----PLVLAAANVVRNIS-YKYREDLSAHLMVAGWDQREGGQ 120
            +      + + ++ +EP     LV A  ++ +  + +  +      L+  GWD+  G Q
Sbjct: 87  TNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQ 146

Query: 121 VY-----GTLGG 127
           +Y     G  GG
Sbjct: 147 LYQSDPSGNYGG 158


>gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens]
          Length = 256

 Score = 34.3 bits (77), Expect = 0.078
 Identities = 28/129 (21%), Positives = 53/129 (41%), Gaps = 12/129 (9%)

Query: 7   VHTGTTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALS------GSAA 60
           V  G+T + +     VV+G + + S  +    R   K+  L + +  A +      G  A
Sbjct: 28  VKKGSTAVGIRGTNIVVLGVEKK-SVAKLQDERTVRKICALDDHVCMAFAVLTIFIGLTA 86

Query: 61  DAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKY-----REDLSAHLMVAGWDQ 115
           DA+ V + A  + + H + +E+P  V      +  +  KY     R       ++ G+D 
Sbjct: 87  DARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISALIVGFDD 146

Query: 116 REGGQVYGT 124
               ++Y T
Sbjct: 147 DGISRLYQT 155


>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
          Length = 1284

 Score = 30.8 bits (68), Expect = 0.86
 Identities = 27/110 (24%), Positives = 40/110 (36%), Gaps = 9/110 (8%)

Query: 89  AANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGTLGGMLTRQPFAIG------GSGST 142
           A   VR +   Y      H   +G  +  G     TLG + +   + +       G GS+
Sbjct: 580 APRPVRLVRVTYVSSEGGH---SGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSS 636

Query: 143 FIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTITAAG 192
            + G V     P  S         DA+ LA      SG ++Y +T T  G
Sbjct: 637 TLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686


>gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens]
          Length = 212

 Score = 29.3 bits (64), Expect = 2.5
 Identities = 17/75 (22%), Positives = 32/75 (42%), Gaps = 5/75 (6%)

Query: 55  LSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKY-----REDLSAHLM 109
           + G  ADA+ V + A  + + H + +E+P  V      +  +  KY     R       +
Sbjct: 37  IRGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSNGRRPFGISAL 96

Query: 110 VAGWDQREGGQVYGT 124
           + G+D     ++Y T
Sbjct: 97  IVGFDDDGISRLYQT 111


>gi|145580600 schlafen family member 5 [Homo sapiens]
          Length = 891

 Score = 28.1 bits (61), Expect = 5.6
 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 5/67 (7%)

Query: 20 GGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADA-QAVADMAAYQLELHGI 78
          G V +G+  R    + +  R+ +K + +  R  CAL  S     +A  +   Y  E HG+
Sbjct: 19 GKVTLGTQQR----QEMDPRLREKQNEIILRAVCALLNSGGGIIKAEIENKGYNYERHGV 74

Query: 79 ELEEPPL 85
           L+ PP+
Sbjct: 75 GLDVPPI 81


>gi|23110944 proteasome alpha 6 subunit [Homo sapiens]
          Length = 246

 Score = 27.7 bits (60), Expect = 7.3
 Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 11/111 (9%)

Query: 23  VMGSDSRVSAGEAVV-NRVFDKLSPLH-----ERIYCALSGSAADAQAVADMAAYQLE-- 74
           V G D  V   +  V +++ D  +  H     E I C ++G  AD+++    A Y+    
Sbjct: 42  VRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANW 101

Query: 75  --LHGIELEEPPLVLAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVY 122
              +G E+    L    A++ +  +       L   +++ G D+ +G QVY
Sbjct: 102 KYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVY 152


>gi|239753084 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]
          Length = 431

 Score = 27.7 bits (60), Expect = 7.3
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 53  CALSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAG 112
           C  +G  A ++  A  AA + EL  +ELEE  LV    +V RN +    +  +A    A 
Sbjct: 146 CLETGELATSEDEA--AALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAE 203

Query: 113 WDQRE 117
            DQ+E
Sbjct: 204 LDQQE 208


>gi|239749701 PREDICTED: hypothetical protein XP_002347123 [Homo
           sapiens]
          Length = 275

 Score = 27.7 bits (60), Expect = 7.3
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 12/58 (20%)

Query: 74  ELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGTLGGMLTR 131
           ++HG++L  PP  LAA           RE    HL   G   R G  + GTL G+L +
Sbjct: 32  DVHGVQLPPPPPTLAAT----------REQRGLHLAQQG--VRCGPALGGTLDGVLAQ 77


>gi|88952907 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]
          Length = 431

 Score = 27.7 bits (60), Expect = 7.3
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 53  CALSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAG 112
           C  +G  A ++  A  AA + EL  +ELEE  LV    +V RN +    +  +A    A 
Sbjct: 146 CLETGELATSEDEA--AALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAE 203

Query: 113 WDQRE 117
            DQ+E
Sbjct: 204 LDQQE 208


>gi|239743967 PREDICTED: hypothetical protein XP_002344251 [Homo
           sapiens]
          Length = 275

 Score = 27.7 bits (60), Expect = 7.3
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 12/58 (20%)

Query: 74  ELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGTLGGMLTR 131
           ++HG++L  PP  LAA           RE    HL   G   R G  + GTL G+L +
Sbjct: 32  DVHGVQLPPPPPTLAAT----------REQRGLHLAQQG--VRCGPALGGTLDGVLAQ 77


>gi|88943925 PREDICTED: Beclin-1-like protein 1 [Homo sapiens]
          Length = 431

 Score = 27.7 bits (60), Expect = 7.3
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 53  CALSGSAADAQAVADMAAYQLELHGIELEEPPLVLAAANVVRNISYKYREDLSAHLMVAG 112
           C  +G  A ++  A  AA + EL  +ELEE  LV    +V RN +    +  +A    A 
Sbjct: 146 CLETGELATSEDEA--AALRAELRDLELEEARLVQELEDVDRNNARAAADLQAAQAEAAE 203

Query: 113 WDQRE 117
            DQ+E
Sbjct: 204 LDQQE 208


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,462,776
Number of Sequences: 37866
Number of extensions: 304353
Number of successful extensions: 613
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 577
Number of HSP's gapped (non-prelim): 34
length of query: 209
length of database: 18,247,518
effective HSP length: 98
effective length of query: 111
effective length of database: 14,536,650
effective search space: 1613568150
effective search space used: 1613568150
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.