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Search of human proteins with 22749303
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 882 0.0
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 76 6e-14
gi|17975763 myelin transcription factor 1 [Homo sapiens] 69 8e-12
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 69 1e-11
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 67 2e-11
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 67 2e-11
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 2e-11
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 2e-11
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 2e-11
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 2e-11
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 2e-11
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 67 3e-11
gi|87298939 hypothetical protein LOC131831 [Homo sapiens] 66 6e-11
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 65 8e-11
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 65 8e-11
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 65 8e-11
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 65 1e-10
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 65 1e-10
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 63 4e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 62 9e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 62 9e-10
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 62 9e-10
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 61 2e-09
gi|28274705 family with sequence similarity 9, member A [Homo sa... 61 2e-09
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 60 3e-09
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 60 3e-09
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 60 3e-09
gi|21361639 DIPB protein [Homo sapiens] 60 3e-09
gi|221219020 NYD-SP11 protein [Homo sapiens] 60 5e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 60 5e-09
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 882 bits (2278), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MTQTLDTREDPLNLGGGGGGGCGCGWAHSASLSSWSSCHRRRPGAPAYNRPHRYSPKTEY 60
MTQTLDTREDPLNLGGGGGGGCGCGWAHSASLSSWSSCHRRRPGAPAYNRPHRYSPKTEY
Sbjct: 1 MTQTLDTREDPLNLGGGGGGGCGCGWAHSASLSSWSSCHRRRPGAPAYNRPHRYSPKTEY 60
Query: 61 GPPRKQPKQQHGPGFWFQPPVCSNWGCWGGPWRPPPPGFWKFPCPVQVFRVYGLHPLCFC 120
GPPRKQPKQQHGPGFWFQPPVCSNWGCWGGPWRPPPPGFWKFPCPVQVFRVYGLHPLCFC
Sbjct: 61 GPPRKQPKQQHGPGFWFQPPVCSNWGCWGGPWRPPPPGFWKFPCPVQVFRVYGLHPLCFC 120
Query: 121 CCSCWSGSWNPGWVKPPGRKKRWGRRGRGLRHHPRHSYPRSPPADVSTLPRPVKLYEWRE 180
CCSCWSGSWNPGWVKPPGRKKRWGRRGRGLRHHPRHSYPRSPPADVSTLPRPVKLYEWRE
Sbjct: 121 CCSCWSGSWNPGWVKPPGRKKRWGRRGRGLRHHPRHSYPRSPPADVSTLPRPVKLYEWRE 180
Query: 181 PGMRAPPNTTQFIMNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGS 240
PGMRAPPNTTQFIMNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGS
Sbjct: 181 PGMRAPPNTTQFIMNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGS 240
Query: 241 KETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEA 300
KETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEA
Sbjct: 241 KETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEA 300
Query: 301 SEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLP 360
SEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLP
Sbjct: 301 SEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLP 360
Query: 361 LEMPLSIFVEAEEKRENFISCTFLNPEQIIPKVPQESLFMAQDFNC 406
LEMPLSIFVEAEEKRENFISCTFLNPEQIIPKVPQESLFMAQDFNC
Sbjct: 361 LEMPLSIFVEAEEKRENFISCTFLNPEQIIPKVPQESLFMAQDFNC 406
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 75.9 bits (185), Expect = 6e-14
Identities = 46/90 (51%), Positives = 61/90 (67%), Gaps = 1/90 (1%)
Query: 263 PNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEV 322
P EE+ ++ + +EEE++ ++EEE ++E + +E EEEEE E+E E E+EEEEE
Sbjct: 872 PALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEF 931
Query: 323 EEAEYVEEGE-EELEEEELEEEEEVLEENE 351
EE EEGE EE EEEE EEEEE LEE E
Sbjct: 932 EEEFEEEEGELEEEEEEEDEEEEEELEEVE 961
Score = 70.9 bits (172), Expect = 2e-12
Identities = 39/72 (54%), Positives = 52/72 (72%), Gaps = 2/72 (2%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEE--EEVEDEEEEVEDEEEEEVEEAEYVEEGEEE 334
EEEEE++ ++EEE ++E + +E EEE EE E+EEEE E+E EEE E E EE E+E
Sbjct: 892 EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951
Query: 335 LEEEELEEEEEV 346
EEEELEE E++
Sbjct: 952 EEEEELEEVEDL 963
Score = 69.3 bits (168), Expect = 6e-12
Identities = 41/79 (51%), Positives = 50/79 (63%), Gaps = 5/79 (6%)
Query: 284 NDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEE 343
+ DEEE ++E E EEEEE E+EEE+ E+EEE+E E E EE EEE EEE EEE
Sbjct: 885 SSDEEEEEEE-----EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEE 939
Query: 344 EEVLEENEQRGEEFHLPLE 362
E+ EE E+ EE LE
Sbjct: 940 GELEEEEEEEDEEEEEELE 958
Score = 58.2 bits (139), Expect = 1e-08
Identities = 38/70 (54%), Positives = 45/70 (64%), Gaps = 6/70 (8%)
Query: 289 EYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE--EEELEEEEEV 346
E D V + + EEEEE EEEE E+EEEEE EE ++ EE E+E E EEE EEEEE
Sbjct: 875 EEDLTVININSSDEEEEE---EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEF 931
Query: 347 LEE-NEQRGE 355
EE E+ GE
Sbjct: 932 EEEFEEEEGE 941
Score = 57.8 bits (138), Expect = 2e-08
Identities = 45/120 (37%), Positives = 60/120 (50%), Gaps = 14/120 (11%)
Query: 227 PARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEE--EKKN 284
P + G PP L+E L N S EE + EEEE E++
Sbjct: 862 PEGTPGGGGPPA-------LEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE 914
Query: 285 DDEEEYDQEVCDAKEA-----SEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEE 339
+DEEEY +E + +E EEE E+E+EEEE ++EEEEE+EE E +E G E EE
Sbjct: 915 EDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974
Score = 55.8 bits (133), Expect = 7e-08
Identities = 34/67 (50%), Positives = 41/67 (61%), Gaps = 3/67 (4%)
Query: 310 EEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFV 369
+EEE E+EEEEE EE E EE EE+ EEEE E+EEE EE E+ EEF E
Sbjct: 887 DEEEEEEEEEEEEEEEE--EEEEEDFEEEE-EDEEEYFEEEEEEEEEFEEEFEEEEGELE 943
Query: 370 EAEEKRE 376
E EE+ +
Sbjct: 944 EEEEEED 950
Score = 44.3 bits (103), Expect = 2e-04
Identities = 45/151 (29%), Positives = 68/151 (45%), Gaps = 25/151 (16%)
Query: 266 EENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEA 325
EE + EEEEE++ + EEE+++E + +E EEE+E E+EEE E E+ E
Sbjct: 911 EEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE-EEEEELEEVEDLEFGTAG 969
Query: 326 EYVEEG----------------------EEELEEEELEEEEEVLEENEQRGEEFHLPLEM 363
VEEG E E E L E EE E E+RG + P
Sbjct: 970 GEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTE-EERGAD-TAPTLA 1027
Query: 364 PLSIFVEAEEKRENFISCTFLNPEQIIPKVP 394
P ++ + E +RE P++++ + P
Sbjct: 1028 PEALPSQGEVEREGESPAAGPPPQELVEEEP 1058
Score = 42.7 bits (99), Expect = 6e-04
Identities = 33/75 (44%), Positives = 38/75 (50%), Gaps = 18/75 (24%)
Query: 304 EEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEM 363
EE++ DEEEEE EE EEE EEEE EEEEE EE E+ EE+
Sbjct: 875 EEDLTVININSSDEEEEEEEE-------EEE-EEEEEEEEEEDFEEEEEDEEEY------ 920
Query: 364 PLSIFVEAEEKRENF 378
F E EE+ E F
Sbjct: 921 ----FEEEEEEEEEF 931
Score = 38.5 bits (88), Expect = 0.011
Identities = 48/170 (28%), Positives = 67/170 (39%), Gaps = 33/170 (19%)
Query: 203 QQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFS 262
++E+ E ++E L + G A G PP L L P +
Sbjct: 946 EEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPT-------LPPALPPPESPPKVQPE 998
Query: 263 PNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDE----------EE 312
P PE P L+ E EE ++E D A EA + EVE E +E
Sbjct: 999 PEPE------PGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQE 1052
Query: 313 EVEDE--------EEEEVEEAEYVEEGEEELEEEELE--EEEEVLEENEQ 352
VE+E EEE + ++ V+ E EEE+E E E L+E EQ
Sbjct: 1053 LVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQ 1102
Score = 31.2 bits (69), Expect = 1.8
Identities = 36/167 (21%), Positives = 65/167 (38%), Gaps = 17/167 (10%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEAS---------PARSSGNDAPPGGSKETWGLQET 249
E+ +E+ E +E + T GE P ++PP E +
Sbjct: 946 EEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEP-EPG 1004
Query: 250 LYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEY----DQEVCDAKEASEE-- 303
L V+ P + +LAP + + E + + E QE+ + + ++
Sbjct: 1005 LLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTL 1064
Query: 304 -EEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
EEE ED ++V+ E EE E E L+E+E ++ +L +
Sbjct: 1065 LEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLAD 1111
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 68.9 bits (167), Expect = 8e-12
Identities = 40/80 (50%), Positives = 49/80 (61%), Gaps = 4/80 (5%)
Query: 266 EENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEA 325
E +Q L P +E+ +E + + +E EEEEE E+EEEE E+EEEEE EE
Sbjct: 230 ERSQDLCPQSLEDAAS----EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEE 285
Query: 326 EYVEEGEEELEEEELEEEEE 345
E EE EEE EEEE EEEEE
Sbjct: 286 EEEEEEEEEEEEEEEEEEEE 305
Score = 65.5 bits (158), Expect = 8e-11
Identities = 39/89 (43%), Positives = 51/89 (57%), Gaps = 1/89 (1%)
Query: 265 PEENQSLAPLLVEEEEEKKNDD-EEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVE 323
PE+ + + + E ++ E+ +E K EEE E+EEEE E+EEE+E E
Sbjct: 218 PEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEE 277
Query: 324 EAEYVEEGEEELEEEELEEEEEVLEENEQ 352
E E EE EEE EEEE EEEEE EE E+
Sbjct: 278 EEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 62.4 bits (150), Expect = 7e-10
Identities = 37/86 (43%), Positives = 53/86 (61%), Gaps = 7/86 (8%)
Query: 278 EEEEKKNDDEEEYDQEVCD-------AKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEE 330
E+ E+ + E Q++C ++E+S+++ + EEE+ E+EEEEE EE + EE
Sbjct: 219 EDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEE 278
Query: 331 GEEELEEEELEEEEEVLEENEQRGEE 356
EEE EEEE EEEEE EE E+ EE
Sbjct: 279 EEEEEEEEEEEEEEEEEEEEEEEEEE 304
Score = 58.9 bits (141), Expect = 8e-09
Identities = 40/113 (35%), Positives = 62/113 (54%), Gaps = 6/113 (5%)
Query: 258 SLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDE 317
SL + + E ++ L EEE+E++ ++EEE +++ + +E EEEEE E+EEEE E+E
Sbjct: 239 SLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298
Query: 318 EEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
EEEE E EE ++ +E + E RG E P + S+ VE
Sbjct: 299 EEEEEE-----EEAAPDVIFQEDTSHTSAQKAPELRGPESPSP-KPEYSVIVE 345
Score = 44.7 bits (104), Expect = 2e-04
Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 10/76 (13%)
Query: 255 QNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEV 314
Q L+ EE + E+EEE++ ++EEE + EEEEE E+EEEE
Sbjct: 251 QKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE----------EEEEEEEEEEEEE 300
Query: 315 EDEEEEEVEEAEYVEE 330
E+EEEE + + E+
Sbjct: 301 EEEEEEAAPDVIFQED 316
Score = 43.5 bits (101), Expect = 3e-04
Identities = 34/108 (31%), Positives = 48/108 (44%)
Query: 269 QSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYV 328
Q A EE EK + E +EV + ++ + E+ +E ++ +
Sbjct: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
Query: 329 EEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRE 376
EE EEE EEEE EEE+E EE E+ EE E E EE+ E
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 30.0 bits (66), Expect = 3.9
Identities = 30/139 (21%), Positives = 61/139 (43%), Gaps = 7/139 (5%)
Query: 213 ALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFSPNPEENQSLA 272
A R ++ +++G + +S N+ P + G F+ + SL+ P
Sbjct: 921 ARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKG 980
Query: 273 PLLVEE--EEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEE 330
L +E + K D E D+E+ K+ ++E ++ + E+E + + +E+
Sbjct: 981 KLSGDEVLSPKFKTSDVLENDEEI---KQLNQEIRDLNESNSEMEAAMVQLQSQISSMEK 1037
Query: 331 GEEELEEEE--LEEEEEVL 347
+ +EEE +EE+ E L
Sbjct: 1038 NLKNIEEENKLIEEQNEAL 1056
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 68.6 bits (166), Expect = 1e-11
Identities = 39/83 (46%), Positives = 57/83 (68%), Gaps = 4/83 (4%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVE-DEEEEVEDEEEEEVEEAEYVEEGEEEL 335
E+ +EK+ D+ EEY ++ + + EE+EE + +EEEE+E+E+E++ E+ E VE+ EEE
Sbjct: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156
Query: 336 EEEELEEEEEVLEENEQRGEEFH 358
EEEE EEEEE EENE H
Sbjct: 157 EEEE-EEEEE--EENEDHQMNCH 176
Score = 53.9 bits (128), Expect = 3e-07
Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 10/97 (10%)
Query: 273 PLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGE 332
P V+ + ++ ++ E D KE E EE ED +E +++EE+E + E EE E
Sbjct: 77 PFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIE 136
Query: 333 EE----------LEEEELEEEEEVLEENEQRGEEFHL 359
EE +E+EE EEEEE EE E+ E+ +
Sbjct: 137 EEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQM 173
Score = 50.1 bits (118), Expect = 4e-06
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 23/116 (19%)
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVE---------- 308
LA ++ Q P + K D + + D E +E+EE E
Sbjct: 57 LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116
Query: 309 -------------DEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENE 351
+EEEE+E+E+E++ E+ E VE+ EEE EEEE EEEEE E+++
Sbjct: 117 PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
Score = 48.9 bits (115), Expect = 8e-06
Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 6/80 (7%)
Query: 278 EEEEKKND---DEEEYDQEVCDAKEASEEEEEVEDEEEEVED--EEEEEVEEAEYVEEGE 332
EE + ND DE+E D+E D +E E EEE ED++E+ ED +EEEE EE E EE E
Sbjct: 108 EEYSEDNDEPGDEDEEDEEG-DREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEE 166
Query: 333 EELEEEELEEEEEVLEENEQ 352
E + + ++++ E+
Sbjct: 167 ENEDHQMNCHNTRIMQDTEK 186
Score = 48.5 bits (114), Expect = 1e-05
Identities = 28/81 (34%), Positives = 46/81 (56%), Gaps = 5/81 (6%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE 336
EE+EE ++EEE ++E ++ E+ E+VEDEEEE +EEEEE EE E E+ +
Sbjct: 122 EEDEEGDREEEEEIEEE---DEDDDEDGEDVEDEEEE--EEEEEEEEEEEENEDHQMNCH 176
Query: 337 EEELEEEEEVLEENEQRGEEF 357
+ ++ E + N + +
Sbjct: 177 NTRIMQDTEKDDNNNDEYDNY 197
Score = 43.5 bits (101), Expect = 3e-04
Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 6/90 (6%)
Query: 273 PLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEG- 331
PL + + + K E ++ K S +E +D + + +E+EE E EY E+
Sbjct: 56 PLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDND 115
Query: 332 -----EEELEEEELEEEEEVLEENEQRGEE 356
+EE EE + EEEEE+ EE+E E+
Sbjct: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDED 145
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 31/126 (24%)
Query: 276 VEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEE--------VEDEEEEE------ 321
+EEE+E ++D E+ + E + +E EEEEE E+E+ + ++D E+++
Sbjct: 135 IEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEY 194
Query: 322 -----------------VEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMP 364
E+A Y E E+ E+ ++NE G + L L++
Sbjct: 195 DNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLD 254
Query: 365 LSIFVE 370
+ E
Sbjct: 255 SDVVRE 260
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 67.4 bits (163), Expect = 2e-11
Identities = 66/204 (32%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKAT---VSGEASPARSSGND---------APPGGSK 241
M + ++ R+Q++ ER+ E R ++ VS R +D +PP +
Sbjct: 169 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 228
Query: 242 ETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS 301
E + L G + P EE L+ L + E+K E E E
Sbjct: 229 ERFEL-----GDGRKP--VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 281
Query: 302 EEEEEVEDEE----EEVEDEEEEEVEEAEYVEEGEEELEEEELEE-EEEVLEENEQRGEE 356
EEEEE E+EE EE E+EEEEE EE E EE E+ EE EE + E+E+R E
Sbjct: 282 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 341
Query: 357 FHLPLEMPLSIF----VEAEEKRE 376
HL L +P S F E+EE E
Sbjct: 342 NHL-LVVPESRFDRDSGESEEAEE 364
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 25/151 (16%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E M +++ + Q+ +++ T S E+S A S GS+E
Sbjct: 243 EKMEERDLLSDLQDISDSERKTSSAESSSAESGS------GSEE---------------- 280
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
EE + EE EE++ ++EEE ++ +++EASE+ E EEE EDEE
Sbjct: 281 ---EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 337
Query: 319 EEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
E V E + + E EE EE + E
Sbjct: 338 RENENHLLVVPESRFDRDSGESEEAEEEVGE 368
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/187 (27%), Positives = 75/187 (40%), Gaps = 5/187 (2%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGF 253
+ Q+ ++ K+ QQ+ R QK + R +A S ++E
Sbjct: 156 LEQLERKRERERKMREQQKEQREQKERE--RRAEERRKEREARREVSAHHRTMREDYSDK 213
Query: 254 VQNPSLAFSPN--PEENQSLAPLLVEEEEEKKNDDEEEYD-QEVCDAKEASEEEEEVEDE 310
V+ + SP P E L +EEK + + D Q++ D++ + E E
Sbjct: 214 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 273
Query: 311 EEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
+EEEEE EE E EE EEEE EEEEE E E E +
Sbjct: 274 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 333
Query: 371 AEEKREN 377
+E+REN
Sbjct: 334 EDEEREN 340
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 270 SLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVE 329
S +P E + D + +E + ++ + +++ D E + E E E
Sbjct: 220 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 279
Query: 330 EGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFIS 380
E EEE EEE EEE EE+E+ EE E S EA E+ +S
Sbjct: 280 EEEEE--EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 328
Score = 36.6 bits (83), Expect = 0.042
Identities = 42/197 (21%), Positives = 75/197 (38%), Gaps = 26/197 (13%)
Query: 204 QEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFSP 263
QEK R+++ +A+ + S R S D+ G ++ T+ +
Sbjct: 18 QEKKRRKEQEEKAEIKRLKN--SDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMED 75
Query: 264 NPEENQSLA--PLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDE---- 317
EE+ SLA P +EK + ++E +E E E E E +D+
Sbjct: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARRE 135
Query: 318 ----------------EEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPL 361
E + +E+ E E E ++ E++ E+ E+ +E E+R EE
Sbjct: 136 WERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ--KERERRAEERRKER 193
Query: 362 EMPLSIFVEAEEKRENF 378
E + RE++
Sbjct: 194 EARREVSAHHRTMREDY 210
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 67.4 bits (163), Expect = 2e-11
Identities = 66/204 (32%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKAT---VSGEASPARSSGND---------APPGGSK 241
M + ++ R+Q++ ER+ E R ++ VS R +D +PP +
Sbjct: 179 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 238
Query: 242 ETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS 301
E + L G + P EE L+ L + E+K E E E
Sbjct: 239 ERFEL-----GDGRKP--VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 291
Query: 302 EEEEEVEDEE----EEVEDEEEEEVEEAEYVEEGEEELEEEELEE-EEEVLEENEQRGEE 356
EEEEE E+EE EE E+EEEEE EE E EE E+ EE EE + E+E+R E
Sbjct: 292 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 351
Query: 357 FHLPLEMPLSIF----VEAEEKRE 376
HL L +P S F E+EE E
Sbjct: 352 NHL-LVVPESRFDRDSGESEEAEE 374
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 25/151 (16%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E M +++ + Q+ +++ T S E+S A S GS+E
Sbjct: 253 EKMEERDLLSDLQDISDSERKTSSAESSSAESGS------GSEE---------------- 290
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
EE + EE EE++ ++EEE ++ +++EASE+ E EEE EDEE
Sbjct: 291 ---EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347
Query: 319 EEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
E V E + + E EE EE + E
Sbjct: 348 RENENHLLVVPESRFDRDSGESEEAEEEVGE 378
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/187 (27%), Positives = 75/187 (40%), Gaps = 5/187 (2%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGF 253
+ Q+ ++ K+ QQ+ R QK + R +A S ++E
Sbjct: 166 LEQLERKRERERKMREQQKEQREQKERE--RRAEERRKEREARREVSAHHRTMREDYSDK 223
Query: 254 VQNPSLAFSPN--PEENQSLAPLLVEEEEEKKNDDEEEYD-QEVCDAKEASEEEEEVEDE 310
V+ + SP P E L +EEK + + D Q++ D++ + E E
Sbjct: 224 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 283
Query: 311 EEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
+EEEEE EE E EE EEEE EEEEE E E E +
Sbjct: 284 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 343
Query: 371 AEEKREN 377
+E+REN
Sbjct: 344 EDEEREN 350
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 270 SLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVE 329
S +P E + D + +E + ++ + +++ D E + E E E
Sbjct: 230 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
Query: 330 EGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFIS 380
E EEE EEE EEE EE+E+ EE E S EA E+ +S
Sbjct: 290 EEEEE--EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 338
Score = 35.4 bits (80), Expect = 0.093
Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE 336
E E E++ EE D+ A+ E ++ E E E + +E+ E E E ++
Sbjct: 126 EREHERRKRHREEQDK----ARREWERQKRREMAREHSR-RERDRLEQLERKRERERKMR 180
Query: 337 EEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENF 378
E++ E+ E+ +E E+R EE E + RE++
Sbjct: 181 EQQKEQREQ--KERERRAEERRKEREARREVSAHHRTMREDY 220
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 67.4 bits (163), Expect = 2e-11
Identities = 66/204 (32%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKAT---VSGEASPARSSGND---------APPGGSK 241
M + ++ R+Q++ ER+ E R ++ VS R +D +PP +
Sbjct: 170 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 229
Query: 242 ETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS 301
E + L G + P EE L+ L + E+K E E E
Sbjct: 230 ERFEL-----GDGRKP--VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 282
Query: 302 EEEEEVEDEE----EEVEDEEEEEVEEAEYVEEGEEELEEEELEE-EEEVLEENEQRGEE 356
EEEEE E+EE EE E+EEEEE EE E EE E+ EE EE + E+E+R E
Sbjct: 283 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 342
Query: 357 FHLPLEMPLSIF----VEAEEKRE 376
HL L +P S F E+EE E
Sbjct: 343 NHL-LVVPESRFDRDSGESEEAEE 365
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 25/151 (16%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E M +++ + Q+ +++ T S E+S A S GS+E
Sbjct: 244 EKMEERDLLSDLQDISDSERKTSSAESSSAESGS------GSEE---------------- 281
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
EE + EE EE++ ++EEE ++ +++EASE+ E EEE EDEE
Sbjct: 282 ---EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 338
Query: 319 EEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
E V E + + E EE EE + E
Sbjct: 339 RENENHLLVVPESRFDRDSGESEEAEEEVGE 369
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/187 (27%), Positives = 75/187 (40%), Gaps = 5/187 (2%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGF 253
+ Q+ ++ K+ QQ+ R QK + R +A S ++E
Sbjct: 157 LEQLERKRERERKMREQQKEQREQKERE--RRAEERRKEREARREVSAHHRTMREDYSDK 214
Query: 254 VQNPSLAFSPN--PEENQSLAPLLVEEEEEKKNDDEEEYD-QEVCDAKEASEEEEEVEDE 310
V+ + SP P E L +EEK + + D Q++ D++ + E E
Sbjct: 215 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 274
Query: 311 EEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
+EEEEE EE E EE EEEE EEEEE E E E +
Sbjct: 275 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 334
Query: 371 AEEKREN 377
+E+REN
Sbjct: 335 EDEEREN 341
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 270 SLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVE 329
S +P E + D + +E + ++ + +++ D E + E E E
Sbjct: 221 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 280
Query: 330 EGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFIS 380
E EEE EEE EEE EE+E+ EE E S EA E+ +S
Sbjct: 281 EEEEE--EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 329
Score = 37.7 bits (86), Expect = 0.019
Identities = 45/198 (22%), Positives = 81/198 (40%), Gaps = 27/198 (13%)
Query: 204 QEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFSP 263
QEK R+++ +A+ + S R S D+ G ++ T+ +
Sbjct: 18 QEKKRRKEQEEKAEIKRLKN--SDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMED 75
Query: 264 NPEENQSLA---PLLV-----------EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVED 309
EE+ SLA P + E+ +EKK+ +E ++E K EE+++
Sbjct: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARR 135
Query: 310 EEE---------EVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLP 360
E E E E + +E+ E E E ++ E++ E+ E+ +E E+R EE
Sbjct: 136 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ--KERERRAEERRKE 193
Query: 361 LEMPLSIFVEAEEKRENF 378
E + RE++
Sbjct: 194 REARREVSAHHRTMREDY 211
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 67.4 bits (163), Expect = 2e-11
Identities = 66/204 (32%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKAT---VSGEASPARSSGND---------APPGGSK 241
M + ++ R+Q++ ER+ E R ++ VS R +D +PP +
Sbjct: 179 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 238
Query: 242 ETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS 301
E + L G + P EE L+ L + E+K E E E
Sbjct: 239 ERFEL-----GDGRKP--VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 291
Query: 302 EEEEEVEDEE----EEVEDEEEEEVEEAEYVEEGEEELEEEELEE-EEEVLEENEQRGEE 356
EEEEE E+EE EE E+EEEEE EE E EE E+ EE EE + E+E+R E
Sbjct: 292 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 351
Query: 357 FHLPLEMPLSIF----VEAEEKRE 376
HL L +P S F E+EE E
Sbjct: 352 NHL-LVVPESRFDRDSGESEEAEE 374
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 25/151 (16%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E M +++ + Q+ +++ T S E+S A S GS+E
Sbjct: 253 EKMEERDLLSDLQDISDSERKTSSAESSSAESGS------GSEE---------------- 290
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
EE + EE EE++ ++EEE ++ +++EASE+ E EEE EDEE
Sbjct: 291 ---EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347
Query: 319 EEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
E V E + + E EE EE + E
Sbjct: 348 RENENHLLVVPESRFDRDSGESEEAEEEVGE 378
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/187 (27%), Positives = 75/187 (40%), Gaps = 5/187 (2%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGF 253
+ Q+ ++ K+ QQ+ R QK + R +A S ++E
Sbjct: 166 LEQLERKRERERKMREQQKEQREQKERE--RRAEERRKEREARREVSAHHRTMREDYSDK 223
Query: 254 VQNPSLAFSPN--PEENQSLAPLLVEEEEEKKNDDEEEYD-QEVCDAKEASEEEEEVEDE 310
V+ + SP P E L +EEK + + D Q++ D++ + E E
Sbjct: 224 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 283
Query: 311 EEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
+EEEEE EE E EE EEEE EEEEE E E E +
Sbjct: 284 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 343
Query: 371 AEEKREN 377
+E+REN
Sbjct: 344 EDEEREN 350
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 270 SLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVE 329
S +P E + D + +E + ++ + +++ D E + E E E
Sbjct: 230 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
Query: 330 EGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFIS 380
E EEE EEE EEE EE+E+ EE E S EA E+ +S
Sbjct: 290 EEEEE--EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 338
Score = 33.1 bits (74), Expect = 0.46
Identities = 44/207 (21%), Positives = 81/207 (39%), Gaps = 36/207 (17%)
Query: 204 QEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFSP 263
QEK R+++ +A+ + S R S D+ G ++ T+ +
Sbjct: 18 QEKKRRKEQEEKAEIKRLKN--SDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMED 75
Query: 264 NPEENQSLA---PLLV-----------EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVED 309
EE+ SLA P + E+ +EKK+ +E ++E K EE+++
Sbjct: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARR 135
Query: 310 EEEEVEDEE------------------EEEVEEAEYVEEGEEELEEEELEEEEEVLEENE 351
E E + E + +E+ E E E ++ E++ E+ E+ +E E
Sbjct: 136 EWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQ--KERE 193
Query: 352 QRGEEFHLPLEMPLSIFVEAEEKRENF 378
+R EE E + RE++
Sbjct: 194 RRAEERRKEREARREVSAHHRTMREDY 220
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 67.4 bits (163), Expect = 2e-11
Identities = 66/204 (32%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKAT---VSGEASPARSSGND---------APPGGSK 241
M + ++ R+Q++ ER+ E R ++ VS R +D +PP +
Sbjct: 147 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 206
Query: 242 ETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS 301
E + L G + P EE L+ L + E+K E E E
Sbjct: 207 ERFEL-----GDGRKP--VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 259
Query: 302 EEEEEVEDEE----EEVEDEEEEEVEEAEYVEEGEEELEEEELEE-EEEVLEENEQRGEE 356
EEEEE E+EE EE E+EEEEE EE E EE E+ EE EE + E+E+R E
Sbjct: 260 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 319
Query: 357 FHLPLEMPLSIF----VEAEEKRE 376
HL L +P S F E+EE E
Sbjct: 320 NHL-LVVPESRFDRDSGESEEAEE 342
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 25/151 (16%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E M +++ + Q+ +++ T S E+S A S GS+E
Sbjct: 221 EKMEERDLLSDLQDISDSERKTSSAESSSAESGS------GSEE---------------- 258
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
EE + EE EE++ ++EEE ++ +++EASE+ E EEE EDEE
Sbjct: 259 ---EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 315
Query: 319 EEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
E V E + + E EE EE + E
Sbjct: 316 RENENHLLVVPESRFDRDSGESEEAEEEVGE 346
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/187 (27%), Positives = 75/187 (40%), Gaps = 5/187 (2%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGF 253
+ Q+ ++ K+ QQ+ R QK + R +A S ++E
Sbjct: 134 LEQLERKRERERKMREQQKEQREQKERE--RRAEERRKEREARREVSAHHRTMREDYSDK 191
Query: 254 VQNPSLAFSPN--PEENQSLAPLLVEEEEEKKNDDEEEYD-QEVCDAKEASEEEEEVEDE 310
V+ + SP P E L +EEK + + D Q++ D++ + E E
Sbjct: 192 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 251
Query: 311 EEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
+EEEEE EE E EE EEEE EEEEE E E E +
Sbjct: 252 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 311
Query: 371 AEEKREN 377
+E+REN
Sbjct: 312 EDEEREN 318
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 270 SLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVE 329
S +P E + D + +E + ++ + +++ D E + E E E
Sbjct: 198 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 257
Query: 330 EGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFIS 380
E EEE EEE EEE EE+E+ EE E S EA E+ +S
Sbjct: 258 EEEEE--EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 306
Score = 35.8 bits (81), Expect = 0.071
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 3/101 (2%)
Query: 278 EEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEE 337
+E+E++++ + + +E A+ E ++ E E E + +E+ E E E ++ E
Sbjct: 91 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSR-RERDRLEQLERKRERERKMRE 149
Query: 338 EELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENF 378
++ E+ E+ +E E+R EE E + RE++
Sbjct: 150 QQKEQREQ--KERERRAEERRKEREARREVSAHHRTMREDY 188
Score = 33.1 bits (74), Expect = 0.46
Identities = 23/101 (22%), Positives = 44/101 (43%), Gaps = 3/101 (2%)
Query: 255 QNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEV 314
++ SLA P + S + ++EK+ + K A +E+E E E +
Sbjct: 45 EDDSLAIKP--PQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKR 102
Query: 315 EDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGE 355
EE+++ E+ + E+ E E + LE+ E++ E
Sbjct: 103 HREEQDKARR-EWERQKRREMAREHSRRERDRLEQLERKRE 142
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 67.4 bits (163), Expect = 2e-11
Identities = 66/204 (32%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKAT---VSGEASPARSSGND---------APPGGSK 241
M + ++ R+Q++ ER+ E R ++ VS R +D +PP +
Sbjct: 136 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 195
Query: 242 ETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS 301
E + L G + P EE L+ L + E+K E E E
Sbjct: 196 ERFEL-----GDGRKP--VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 248
Query: 302 EEEEEVEDEE----EEVEDEEEEEVEEAEYVEEGEEELEEEELEE-EEEVLEENEQRGEE 356
EEEEE E+EE EE E+EEEEE EE E EE E+ EE EE + E+E+R E
Sbjct: 249 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 308
Query: 357 FHLPLEMPLSIF----VEAEEKRE 376
HL L +P S F E+EE E
Sbjct: 309 NHL-LVVPESRFDRDSGESEEAEE 331
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 25/151 (16%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E M +++ + Q+ +++ T S E+S A S GS+E
Sbjct: 210 EKMEERDLLSDLQDISDSERKTSSAESSSAESGS------GSEE---------------- 247
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
EE + EE EE++ ++EEE ++ +++EASE+ E EEE EDEE
Sbjct: 248 ---EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 304
Query: 319 EEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
E V E + + E EE EE + E
Sbjct: 305 RENENHLLVVPESRFDRDSGESEEAEEEVGE 335
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/187 (27%), Positives = 75/187 (40%), Gaps = 5/187 (2%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGF 253
+ Q+ ++ K+ QQ+ R QK + R +A S ++E
Sbjct: 123 LEQLERKRERERKMREQQKEQREQKERE--RRAEERRKEREARREVSAHHRTMREDYSDK 180
Query: 254 VQNPSLAFSPN--PEENQSLAPLLVEEEEEKKNDDEEEYD-QEVCDAKEASEEEEEVEDE 310
V+ + SP P E L +EEK + + D Q++ D++ + E E
Sbjct: 181 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 240
Query: 311 EEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
+EEEEE EE E EE EEEE EEEEE E E E +
Sbjct: 241 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 300
Query: 371 AEEKREN 377
+E+REN
Sbjct: 301 EDEEREN 307
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 270 SLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVE 329
S +P E + D + +E + ++ + +++ D E + E E E
Sbjct: 187 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 246
Query: 330 EGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFIS 380
E EEE EEE EEE EE+E+ EE E S EA E+ +S
Sbjct: 247 EEEEE--EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 295
Score = 37.4 bits (85), Expect = 0.025
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 11/111 (9%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEE---------EVEDEEEEEVEEAEY 327
E+ +EKK+ +E ++E K EE+++ E E E E + +E+ E
Sbjct: 69 EKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLER 128
Query: 328 VEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENF 378
E E ++ E++ E+ E+ +E E+R EE E + RE++
Sbjct: 129 KRERERKMREQQKEQREQ--KERERRAEERRKEREARREVSAHHRTMREDY 177
Score = 33.9 bits (76), Expect = 0.27
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 2/130 (1%)
Query: 226 SPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKND 285
S R S D+ G ++ T+ + EE+ SLA + ++ +K
Sbjct: 4 SDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLA-IKPPQQMSRKEK 62
Query: 286 DEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEE 345
D++ + K A +E+E E E + EE+++ E+ + E+ E E +
Sbjct: 63 VHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARR-EWERQKRREMAREHSRRERD 121
Query: 346 VLEENEQRGE 355
LE+ E++ E
Sbjct: 122 RLEQLERKRE 131
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 67.4 bits (163), Expect = 2e-11
Identities = 66/204 (32%), Positives = 91/204 (44%), Gaps = 29/204 (14%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKAT---VSGEASPARSSGND---------APPGGSK 241
M + ++ R+Q++ ER+ E R ++ VS R +D +PP +
Sbjct: 181 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR 240
Query: 242 ETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS 301
E + L G + P EE L+ L + E+K E E E
Sbjct: 241 ERFEL-----GDGRKP--VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 293
Query: 302 EEEEEVEDEE----EEVEDEEEEEVEEAEYVEEGEEELEEEELEE-EEEVLEENEQRGEE 356
EEEEE E+EE EE E+EEEEE EE E EE E+ EE EE + E+E+R E
Sbjct: 294 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 353
Query: 357 FHLPLEMPLSIF----VEAEEKRE 376
HL L +P S F E+EE E
Sbjct: 354 NHL-LVVPESRFDRDSGESEEAEE 376
Score = 53.5 bits (127), Expect = 3e-07
Identities = 42/151 (27%), Positives = 66/151 (43%), Gaps = 25/151 (16%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E M +++ + Q+ +++ T S E+S A S GS+E
Sbjct: 255 EKMEERDLLSDLQDISDSERKTSSAESSSAESGS------GSEE---------------- 292
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
EE + EE EE++ ++EEE ++ +++EASE+ E EEE EDEE
Sbjct: 293 ---EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 349
Query: 319 EEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
E V E + + E EE EE + E
Sbjct: 350 RENENHLLVVPESRFDRDSGESEEAEEEVGE 380
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/187 (27%), Positives = 75/187 (40%), Gaps = 5/187 (2%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGF 253
+ Q+ ++ K+ QQ+ R QK + R +A S ++E
Sbjct: 168 LEQLERKRERERKMREQQKEQREQKERE--RRAEERRKEREARREVSAHHRTMREDYSDK 225
Query: 254 VQNPSLAFSPN--PEENQSLAPLLVEEEEEKKNDDEEEYD-QEVCDAKEASEEEEEVEDE 310
V+ + SP P E L +EEK + + D Q++ D++ + E E
Sbjct: 226 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 285
Query: 311 EEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
+EEEEE EE E EE EEEE EEEEE E E E +
Sbjct: 286 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 345
Query: 371 AEEKREN 377
+E+REN
Sbjct: 346 EDEEREN 352
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Query: 270 SLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVE 329
S +P E + D + +E + ++ + +++ D E + E E E
Sbjct: 232 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 291
Query: 330 EGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFIS 380
E EEE EEE EEE EE+E+ EE E S EA E+ +S
Sbjct: 292 EEEEE--EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 340
Score = 35.8 bits (81), Expect = 0.071
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 3/101 (2%)
Query: 278 EEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEE 337
+E+E++++ + + +E A+ E ++ E E E + +E+ E E E ++ E
Sbjct: 125 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSR-RERDRLEQLERKRERERKMRE 183
Query: 338 EELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENF 378
++ E+ E+ +E E+R EE E + RE++
Sbjct: 184 QQKEQREQ--KERERRAEERRKEREARREVSAHHRTMREDY 222
Score = 34.7 bits (78), Expect = 0.16
Identities = 36/162 (22%), Positives = 65/162 (40%), Gaps = 13/162 (8%)
Query: 204 QEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFSP 263
QEK R+++ +A+ + S R S D+ G ++ T+ +
Sbjct: 18 QEKKRRKEQEEKAEIKRLKN--SDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMED 75
Query: 264 NPEENQSLA---PLLVEEEE-------EKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEE 313
EE+ SLA P + +E EK+ + K A +E+E E E +
Sbjct: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRK 135
Query: 314 VEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGE 355
EE+++ E+ + E+ E E + LE+ E++ E
Sbjct: 136 RHREEQDKARR-EWERQKRREMAREHSRRERDRLEQLERKRE 176
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 67.0 bits (162), Expect = 3e-11
Identities = 67/223 (30%), Positives = 93/223 (41%), Gaps = 24/223 (10%)
Query: 148 RGLRHHPRHSYPRSPPADVSTLPRPVKLYEWREPGMRAPPNTTQFIMNQIYEDMRQQEKV 207
+G R P+ P + P KL P + P I E+ QE V
Sbjct: 698 QGARAQPQAKAESKPEEE-----EPAKL-----PAVTVTPAPVPDIKGDQKENPGGQEDV 747
Query: 208 ERQQEA--LRAQKATVSGEASPARSSGNDAPPGGS--KETWGLQETLYGFVQNPSLAFSP 263
+ + ++ +GE SG + P G ET G E ++ + A
Sbjct: 748 AEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEEC----EDENEAEGK 803
Query: 264 NPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAK-EASEEEEEVEDEE-EEVEDEEEEE 321
E + + E+ E K N+ E E + + EA +E+ VED + D EEEE
Sbjct: 804 GDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEE 863
Query: 322 VEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMP 364
EE EE EEE EEEE EEEEE EE E++G E L L+ P
Sbjct: 864 EEE----EEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWP 902
>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
Length = 663
Score = 65.9 bits (159), Expect = 6e-11
Identities = 39/62 (62%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Query: 296 DAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGE 355
D KE SEEE E E+EEEEVE+EEEE EE E VEE EEE+ EEEL EE+ LE E E
Sbjct: 17 DQKE-SEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSE 75
Query: 356 EF 357
E+
Sbjct: 76 EY 77
Score = 58.2 bits (139), Expect = 1e-08
Identities = 38/68 (55%), Positives = 44/68 (64%), Gaps = 11/68 (16%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE 336
E EEE + ++EEE E EEEEEVE+EEEEVE+EEEE VEE E V E E+ELE
Sbjct: 20 ESEEELEEEEEEE---------EVEEEEEEVEEEEEEVEEEEEEVVEE-ELVGE-EQELE 68
Query: 337 EEELEEEE 344
E EE
Sbjct: 69 APETFSEE 76
Score = 54.3 bits (129), Expect = 2e-07
Identities = 34/63 (53%), Positives = 40/63 (63%), Gaps = 12/63 (19%)
Query: 298 KEASEEEEEVEDEEEEVE-DEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEE 356
K+ E EEE+E+EEEE E +EEEEEVEE EEEE+EEEEE + E E GEE
Sbjct: 16 KDQKESEEELEEEEEEEEVEEEEEEVEE-----------EEEEVEEEEEEVVEEELVGEE 64
Query: 357 FHL 359
L
Sbjct: 65 QEL 67
Score = 32.0 bits (71), Expect = 1.0
Identities = 21/44 (47%), Positives = 25/44 (56%), Gaps = 3/44 (6%)
Query: 329 EEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAE 372
+E EEELEEEE EEE +EE E+ EE +E VE E
Sbjct: 19 KESEEELEEEE---EEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 65.5 bits (158), Expect = 8e-11
Identities = 43/118 (36%), Positives = 70/118 (59%), Gaps = 12/118 (10%)
Query: 247 QETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEE 306
+E+++ +Q + + E+N+ AP EE++E ++D+EE ++ E EEEEE
Sbjct: 132 RESIFELLQQITYLDGFDQEDNE--APDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE 189
Query: 307 VEDEEEEVEDEEEEEVEEAEYVEEGEEE-----LEEEELEEEE---EVLEENEQRGEE 356
+EEEE EDE+E+E E + EGEEE L +EE+++EE + +EE E+ EE
Sbjct: 190 --EEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 245
Score = 56.6 bits (135), Expect = 4e-08
Identities = 36/78 (46%), Positives = 50/78 (64%), Gaps = 8/78 (10%)
Query: 266 EENQSLAPL-LVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDE---EEEVEDEEEEE 321
EEN++ P EEEEE++ +DE+E + E E E EEEV +EE++DEE+++
Sbjct: 174 EENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDD 233
Query: 322 VEEAEYVEEGEEELEEEE 339
+YVEEGEEE EEEE
Sbjct: 234 ----DYVEEGEEEEEEEE 247
Score = 50.4 bits (119), Expect = 3e-06
Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Query: 290 YDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
+DQE +A ++ EE++E DE++E E+E E E Y EE EEE EE+E E+E+E
Sbjct: 148 FDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG-YEEEEEEEEEEDEDEDEDEDEAG 206
Query: 350 NEQRGEEFHLPLEMPLSIFVEAEEKRENFI 379
+E E + L + ++ EE ++++
Sbjct: 207 SELGEGEEEVGLSYLMKEEIQDEEDDDDYV 236
Score = 41.6 bits (96), Expect = 0.001
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 8/76 (10%)
Query: 288 EEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEE--------LEEEE 339
E+Y + + + + + + E+ E D EEE+ E+ + +E EEE EEEE
Sbjct: 129 EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 188
Query: 340 LEEEEEVLEENEQRGE 355
EEEEE +E+E E
Sbjct: 189 EEEEEEDEDEDEDEDE 204
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 65.5 bits (158), Expect = 8e-11
Identities = 43/118 (36%), Positives = 70/118 (59%), Gaps = 12/118 (10%)
Query: 247 QETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEE 306
+E+++ +Q + + E+N+ AP EE++E ++D+EE ++ E EEEEE
Sbjct: 91 RESIFELLQQITYLDGFDQEDNE--APDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE 148
Query: 307 VEDEEEEVEDEEEEEVEEAEYVEEGEEE-----LEEEELEEEE---EVLEENEQRGEE 356
+EEEE EDE+E+E E + EGEEE L +EE+++EE + +EE E+ EE
Sbjct: 149 --EEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 204
Score = 56.6 bits (135), Expect = 4e-08
Identities = 36/78 (46%), Positives = 50/78 (64%), Gaps = 8/78 (10%)
Query: 266 EENQSLAPL-LVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDE---EEEVEDEEEEE 321
EEN++ P EEEEE++ +DE+E + E E E EEEV +EE++DEE+++
Sbjct: 133 EENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDD 192
Query: 322 VEEAEYVEEGEEELEEEE 339
+YVEEGEEE EEEE
Sbjct: 193 ----DYVEEGEEEEEEEE 206
Score = 50.4 bits (119), Expect = 3e-06
Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Query: 290 YDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
+DQE +A ++ EE++E DE++E E+E E E Y EE EEE EE+E E+E+E
Sbjct: 107 FDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG-YEEEEEEEEEEDEDEDEDEDEAG 165
Query: 350 NEQRGEEFHLPLEMPLSIFVEAEEKRENFI 379
+E E + L + ++ EE ++++
Sbjct: 166 SELGEGEEEVGLSYLMKEEIQDEEDDDDYV 195
Score = 41.6 bits (96), Expect = 0.001
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 8/76 (10%)
Query: 288 EEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEE--------LEEEE 339
E+Y + + + + + + E+ E D EEE+ E+ + +E EEE EEEE
Sbjct: 88 EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 147
Query: 340 LEEEEEVLEENEQRGE 355
EEEEE +E+E E
Sbjct: 148 EEEEEEDEDEDEDEDE 163
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 65.5 bits (158), Expect = 8e-11
Identities = 43/118 (36%), Positives = 70/118 (59%), Gaps = 12/118 (10%)
Query: 247 QETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEE 306
+E+++ +Q + + E+N+ AP EE++E ++D+EE ++ E EEEEE
Sbjct: 84 RESIFELLQQITYLDGFDQEDNE--APDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEE 141
Query: 307 VEDEEEEVEDEEEEEVEEAEYVEEGEEE-----LEEEELEEEE---EVLEENEQRGEE 356
+EEEE EDE+E+E E + EGEEE L +EE+++EE + +EE E+ EE
Sbjct: 142 --EEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEE 197
Score = 56.6 bits (135), Expect = 4e-08
Identities = 36/78 (46%), Positives = 50/78 (64%), Gaps = 8/78 (10%)
Query: 266 EENQSLAPL-LVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDE---EEEVEDEEEEE 321
EEN++ P EEEEE++ +DE+E + E E E EEEV +EE++DEE+++
Sbjct: 126 EENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDD 185
Query: 322 VEEAEYVEEGEEELEEEE 339
+YVEEGEEE EEEE
Sbjct: 186 ----DYVEEGEEEEEEEE 199
Score = 50.4 bits (119), Expect = 3e-06
Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Query: 290 YDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
+DQE +A ++ EE++E DE++E E+E E E Y EE EEE EE+E E+E+E
Sbjct: 100 FDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG-YEEEEEEEEEEDEDEDEDEDEAG 158
Query: 350 NEQRGEEFHLPLEMPLSIFVEAEEKRENFI 379
+E E + L + ++ EE ++++
Sbjct: 159 SELGEGEEEVGLSYLMKEEIQDEEDDDDYV 188
Score = 41.6 bits (96), Expect = 0.001
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 8/76 (10%)
Query: 288 EEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEE--------LEEEE 339
E+Y + + + + + + E+ E D EEE+ E+ + +E EEE EEEE
Sbjct: 81 EDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE 140
Query: 340 LEEEEEVLEENEQRGE 355
EEEEE +E+E E
Sbjct: 141 EEEEEEDEDEDEDEDE 156
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 65.1 bits (157), Expect = 1e-10
Identities = 49/120 (40%), Positives = 60/120 (50%), Gaps = 10/120 (8%)
Query: 266 EENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEE----EEVEDEEEEE 321
EE L+ L + E+K E E E EEEEE E+EE EE E+EEEEE
Sbjct: 2 EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 61
Query: 322 VEEAEYVEEGEEELEEEELEE-EEEVLEENEQRGEEFHLPLEMPLSIF----VEAEEKRE 376
EE E EE E+ EE EE + E+E+R E HL L +P S F E+EE E
Sbjct: 62 EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL-LVVPESRFDRDSGESEEAEE 120
Score = 52.0 bits (123), Expect = 1e-06
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 25/149 (16%)
Query: 201 MRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLA 260
M +++ + Q+ +++ T S E+S A S GS+E
Sbjct: 1 MEERDLLSDLQDISDSERKTSSAESSSAESGS------GSEE------------------ 36
Query: 261 FSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEE 320
EE + EE EE++ ++EEE ++ +++EASE+ E EEE EDEE E
Sbjct: 37 -EEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 95
Query: 321 EVEEAEYVEEGEEELEEEELEEEEEVLEE 349
V E + + E EE EE + E
Sbjct: 96 NENHLLVVPESRFDRDSGESEEAEEEVGE 124
Score = 46.6 bits (109), Expect = 4e-05
Identities = 30/86 (34%), Positives = 39/86 (45%)
Query: 292 QEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENE 351
Q++ D++ + E E +EEEEE EE E EE EEEE EEEEE E
Sbjct: 11 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 70
Query: 352 QRGEEFHLPLEMPLSIFVEAEEKREN 377
E E + +E+REN
Sbjct: 71 NSEEASEQSAEEVSEEEMSEDEEREN 96
Score = 37.4 bits (85), Expect = 0.025
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 296 DAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGE 355
+ ++ + +++ D E + E E EE EEE EEE EEE EE+E+ E
Sbjct: 2 EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE--EEEEEEEGSTSEESEEEEE 59
Query: 356 EFHLPLEMPLSIFVEAEEKRENFIS 380
E E S EA E+ +S
Sbjct: 60 EEEEEEEETGSNSEEASEQSAEEVS 84
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 64.7 bits (156), Expect = 1e-10
Identities = 56/159 (35%), Positives = 73/159 (45%), Gaps = 11/159 (6%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E+ + K E + E + ++ GE +G KE G +E G +
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAG--------KEEKGEEEGDQG--EGEE 798
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
EE + + E EE K + EEE ++ + +E EEEE E EEEE E +
Sbjct: 799 EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKG 858
Query: 319 EEEVEEAEYVEEGEE-ELEEEELEEEEEVLEENEQRGEE 356
EEE EE E EEGEE E E EE E E E EE E GEE
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897
Score = 62.0 bits (149), Expect = 9e-10
Identities = 58/159 (36%), Positives = 74/159 (46%), Gaps = 10/159 (6%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E R++E+ ER++E RA K E + G +E E G V+
Sbjct: 765 EGEREKEEGERKKEE-RAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGK 823
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEE-EVEDEEEEVEDE 317
EE + EEEE + ++E E ++E + K E EE E E+E EE E E
Sbjct: 824 GEREEEEEEGEG------EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877
Query: 318 EEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEE 356
EEE E E EEGE E EEEE E E E EE E GEE
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGE--EEGEGEGEE 914
Score = 58.9 bits (141), Expect = 8e-09
Identities = 42/81 (51%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGE-EEL 335
EEEE + +EEE + E + E EE E E EEEE E E EEE E E EEGE EE
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Query: 336 EEEELEEEEEVLEENEQRGEE 356
E E EEEEE E E GEE
Sbjct: 1009 GEGEGEEEEEGEVEGEVEGEE 1029
Score = 57.4 bits (137), Expect = 2e-08
Identities = 38/82 (46%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE 336
E EEE + + EEE + EV E E E E E+EE E E EE E+ E E EE E
Sbjct: 1004 EGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEE 1063
Query: 337 EEELEEEEEVLEENE-QRGEEF 357
EEE + +E EENE Q GEE+
Sbjct: 1064 EEEGKYQETGEEENERQDGEEY 1085
Score = 56.6 bits (135), Expect = 4e-08
Identities = 43/82 (52%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEE-EVEDEE-EEEVEEAEYVEEGEEE 334
EEE E + +D E +E E EEE E E EEE E E EE E E EE E EGEEE
Sbjct: 934 EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEE 993
Query: 335 LEEEELEEEEEVLEENEQRGEE 356
EEE EEE E EE E GEE
Sbjct: 994 EGEEEGEEEGEGEEEGEGEGEE 1015
Score = 56.6 bits (135), Expect = 4e-08
Identities = 40/79 (50%), Positives = 45/79 (56%), Gaps = 6/79 (7%)
Query: 278 EEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEE 337
EEEE + + EEE +E E EE E E+ E E E+EEE EVE EEGE E EE
Sbjct: 982 EEEEGEGEGEEEEGEE-----EGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE 1036
Query: 338 EELEEEEEVLEENEQRGEE 356
EE EEE E E E GEE
Sbjct: 1037 EEGEEEGEE-REKEGEGEE 1054
Score = 55.8 bits (133), Expect = 7e-08
Identities = 40/78 (51%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
Query: 278 EEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEE 337
EEEE + + EEE + E + E EEEE E E EE E EEE E EE E EEGE E EE
Sbjct: 958 EEEEGEGEGEEEGEGEG-EEGEGEGEEEEGEGEGEEEEGEEEGE-EEGEGEEEGEGEGEE 1015
Query: 338 EELEEEEEVLEENEQRGE 355
EE E E +E E GE
Sbjct: 1016 EEEGEVEGEVEGEEGEGE 1033
Score = 55.5 bits (132), Expect = 9e-08
Identities = 51/157 (32%), Positives = 67/157 (42%), Gaps = 20/157 (12%)
Query: 203 QQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFS 262
++ K ER++E + GE G + G E G +
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE--------------G 865
Query: 263 PNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEV 322
EE + EEE E + ++E E + E + + EEE E E EEEE E + EEE
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG 925
Query: 323 EEAE---YVEEGEEELEEEELEEEEEVLEENEQRGEE 356
EE E EEGE E E+ E E EE EE E GEE
Sbjct: 926 EEGEGEGEEEEGEGEGEDGEGEGEE---EEGEWEGEE 959
Score = 55.1 bits (131), Expect = 1e-07
Identities = 38/83 (45%), Positives = 45/83 (54%), Gaps = 3/83 (3%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAE---YVEEGEE 333
EEEE + +EEE ++E + E EE E +EEEE E E E E EE E EEGEE
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE 1041
Query: 334 ELEEEELEEEEEVLEENEQRGEE 356
E EE E E E E N + EE
Sbjct: 1042 EGEEREKEGEGEENRRNREEEEE 1064
Score = 54.7 bits (130), Expect = 1e-07
Identities = 40/94 (42%), Positives = 53/94 (56%), Gaps = 12/94 (12%)
Query: 275 LVEEEEEKKNDDEEEY--DQEVCDAKEASEEEEEVEDEE-----EEVEDEEEEEVEEAEY 327
L E+EE KK D EE+ ++E KE ++E EE +EE EE D EEEE +E E
Sbjct: 696 LAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEG 755
Query: 328 VEEGEEE-----LEEEELEEEEEVLEENEQRGEE 356
EEGE E E+EE E ++E E++GEE
Sbjct: 756 KEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE 789
Score = 52.8 bits (125), Expect = 6e-07
Identities = 38/96 (39%), Positives = 50/96 (52%), Gaps = 17/96 (17%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEE-----------EEEVEDEEEEVEDEEE------ 319
EEEEEK+ + +EE + E + + EE EE+ E+E ++ E EEE
Sbjct: 746 EEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRG 805
Query: 320 EEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGE 355
EE EE VE GE E + E EEEEE E E+ GE
Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE 841
Score = 51.2 bits (121), Expect = 2e-06
Identities = 36/79 (45%), Positives = 45/79 (56%), Gaps = 4/79 (5%)
Query: 279 EEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEE-GEEELEE 337
EEE +EEE D+E + KE +EE E EEVE E E+E E + E G+EE E
Sbjct: 732 EEEHGEGEEEEGDREEEEEKEGEGKEE---GEGEEVEGEREKEEGERKKEERAGKEEKGE 788
Query: 338 EELEEEEEVLEENEQRGEE 356
EE ++ E EE E RGEE
Sbjct: 789 EEGDQGEGEEEETEGRGEE 807
Score = 50.8 bits (120), Expect = 2e-06
Identities = 37/84 (44%), Positives = 44/84 (52%), Gaps = 4/84 (4%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEE----EVEDEEEEVEDEEEEEVEEAEYVEEGE 332
EEE E K ++E E + + +E E E E E+EE E E EEEE E E EGE
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973
Query: 333 EELEEEELEEEEEVLEENEQRGEE 356
E E E EEEE E E+ GEE
Sbjct: 974 GEEGEGEGEEEEGEGEGEEEEGEE 997
Score = 50.4 bits (119), Expect = 3e-06
Identities = 42/97 (43%), Positives = 51/97 (52%), Gaps = 17/97 (17%)
Query: 277 EEEEEKKNDDEE---EYDQEVCDAKEASEEEE--------EVEDEEEEVEDEEEEEVEEA 325
EEE E + ++EE + ++E + + EEEE E E EEEE E E EEE E
Sbjct: 905 EEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG 964
Query: 326 EYVEEGEEELEEEELEEEEE------VLEENEQRGEE 356
E EEGE E EE E E EEE EE E+ GEE
Sbjct: 965 EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001
Score = 48.5 bits (114), Expect = 1e-05
Identities = 52/160 (32%), Positives = 68/160 (42%), Gaps = 3/160 (1%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E ++E+ E ++E ++ GE G + G E G + G +
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
E E EEE + + EEE + E +E E E E E+EE E E E+
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE-EGEGKGEEEGEEGEGEGEEEEGEGEGED 943
Query: 319 -EEEVEEAEYVEEGEEELEEEELEEE-EEVLEENEQRGEE 356
E E EE E EGEEE E E EEE E EE E GEE
Sbjct: 944 GEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEE 983
Score = 44.3 bits (103), Expect = 2e-04
Identities = 36/95 (37%), Positives = 49/95 (51%), Gaps = 5/95 (5%)
Query: 266 EENQSLAPLLVEEEEEKKNDDEE--EYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVE 323
EE S A +EE EK D+ E ++ KE +E+EE + + EE E +E E+
Sbjct: 660 EEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGH 719
Query: 324 EAEYVEEGEEELEEEELEEEEEV---LEENEQRGE 355
+ E +E EE EEE E EEE EE E+ GE
Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/81 (38%), Positives = 44/81 (54%), Gaps = 7/81 (8%)
Query: 266 EENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEA 325
EE + VE EE + +EEE ++E E E+E E E+ E+EEE EE
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEEE----GEEREKEGEGEENRRNREEEEE---EEG 1067
Query: 326 EYVEEGEEELEEEELEEEEEV 346
+Y E GEEE E ++ EE ++V
Sbjct: 1068 KYQETGEEENERQDGEEYKKV 1088
Score = 35.8 bits (81), Expect = 0.071
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 27/118 (22%)
Query: 258 SLAFSP-NPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEA---------------- 300
SL SP ++ Q L ++ +NDD +EY+ E+ + KE
Sbjct: 514 SLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYE-EMSEMKEGKACKQHVSQGIFMTQP 572
Query: 301 -------SEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE-EEELEEEEEVLEEN 350
S+EE E+ +E+E ED + +EE E VE EE ++ +E+ E+L ++
Sbjct: 573 ATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQE-VEANEENVKVHGGRKEKTEILSDD 629
Score = 30.8 bits (68), Expect = 2.3
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDE-----EEEVEDEEEEEVEEAEYVE 329
EEEE ++ +E E + E + + EEEEE E + EEE E ++ EE ++ ++
Sbjct: 1035 EEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIK 1092
Score = 30.8 bits (68), Expect = 2.3
Identities = 18/54 (33%), Positives = 29/54 (53%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEE 330
EE EE+ + E+E + E EEEEE + +E E+ E ++ EE + V +
Sbjct: 1037 EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSK 1090
Score = 29.6 bits (65), Expect = 5.1
Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
Query: 298 KEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEE---LEEEEEVLEENEQRG 354
+E S E +DEE E + E+++ E E EGE+EL E+E + EE ++ ++G
Sbjct: 660 EEGSSGAEHWQDEERE-KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQG 718
Query: 355 EEFHLPLEM 363
+ EM
Sbjct: 719 HQKERNQEM 727
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 63.2 bits (152), Expect = 4e-10
Identities = 38/66 (57%), Positives = 47/66 (71%), Gaps = 2/66 (3%)
Query: 293 EVCDAKEASE-EEEEVEDEEEEVEDEE-EEEVEEAEYVEEGEEELEEEELEEEEEVLEEN 350
E C A++ EEEEVE+EEEEVE+EE EEE EE E EE EEE EE+E EEE+E +
Sbjct: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
Query: 351 EQRGEE 356
E++ EE
Sbjct: 168 EEKVEE 173
Score = 56.2 bits (134), Expect = 5e-08
Identities = 34/58 (58%), Positives = 41/58 (70%), Gaps = 6/58 (10%)
Query: 296 DAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELE----EEEEVLEE 349
+ +E EEEEEVE+EE+E E EE+EE EE E EE EE+ EEEE E EEE+V EE
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKE--EEKEEDEEEEEKEGKKMEEEKVEEE 174
Score = 55.5 bits (132), Expect = 9e-08
Identities = 54/185 (29%), Positives = 88/185 (47%), Gaps = 22/185 (11%)
Query: 160 RSPPADVSTLPRPVKLYEWREPGMRAPPNTTQFIM-NQIYEDMRQQEKVERQQEALRAQK 218
R PP +T G R P T M +Q +++R +E +++ L+
Sbjct: 11 RKPPPSHATGVSTQSFQILGREGWRVKPAHTLLAMTSQRNKELRPSTCLEVEEKWLQRWA 70
Query: 219 ATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEE 278
+ P + SG + WG + G + + + EE + L VEE
Sbjct: 71 VGL-----PVKDSGVS-----QAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEE 120
Query: 279 EEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEE 338
EE + ++EEE ++E E+EEE E++EEE E EEE+E +E E +EG +++EEE
Sbjct: 121 EEVE--EEEEEVEEE--------EKEEEKEEDEEEEEKEEEKEEDEEEEEKEG-KKMEEE 169
Query: 339 ELEEE 343
++EEE
Sbjct: 170 KVEEE 174
Score = 49.3 bits (116), Expect = 6e-06
Identities = 30/57 (52%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Query: 297 AKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQR 353
A+E S ++ +EEE EEEEEVEE E EE EE+ EEEE EEE+E EE E++
Sbjct: 107 AEECSAQQGLPVEEEEVE--EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK 161
Score = 48.1 bits (113), Expect = 1e-05
Identities = 22/52 (42%), Positives = 36/52 (69%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYV 328
E+EEEK+ D+EEE +E + E EE+E + EEE+VE+E + E++ +Y+
Sbjct: 134 EKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQYL 185
Score = 43.5 bits (101), Expect = 3e-04
Identities = 29/60 (48%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 297 AKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEE 356
A+ A+ EE ++ +EEE E EE E VEE E+E E+EE EEEEE EE E+ EE
Sbjct: 100 ARTAALVAEECSAQQGLPVEEEEVE-EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE 158
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 62.0 bits (149), Expect = 9e-10
Identities = 47/194 (24%), Positives = 94/194 (48%), Gaps = 20/194 (10%)
Query: 194 MNQIYEDM--RQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLY 251
+NQ E+ RQ+EK++ ++E ++ Q+ + + R + +E QE +
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ--EEMMWEKEEKMRRQEEMM 339
Query: 252 GFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS---------E 302
+ E + + E+EEK+ ++E+ +QE +EA E
Sbjct: 340 WEKEEKIRELEEKMHEQEK-----IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 394
Query: 303 EEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEE--LEEEEEVLEENEQRGEEFHLP 360
+EE++ ++EE ++++EE+ E+ E + E EEE++E+E + +EE + E E++ E
Sbjct: 395 QEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454
Query: 361 LEMPLSIFVEAEEK 374
+ + E EEK
Sbjct: 455 IREQEEMMQEQEEK 468
Score = 55.1 bits (131), Expect = 1e-07
Identities = 42/164 (25%), Positives = 82/164 (50%), Gaps = 26/164 (15%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E Q+EK+ RQ+E +R Q+ + + R +E QE G
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ---------EEMMQEQEEKMG------ 470
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEE---EYDQEVCDAKEASEEEEEV-EDEEEEV 314
E ++E+EEK EE E ++++ + +E E+EE+ +++EE++
Sbjct: 471 -----EQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 525
Query: 315 EDEEEEEVEEAEYVEEGEEEL--EEEELEEEEEVLEENEQRGEE 356
++EE+ E+ E ++E EE++ +EE++ E+E L + E++ +E
Sbjct: 526 WEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 53.5 bits (127), Expect = 3e-07
Identities = 26/84 (30%), Positives = 58/84 (69%), Gaps = 6/84 (7%)
Query: 276 VEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEEL 335
+ E+EEK + EE ++ ++ E+EE++ ++EEE++++EE+ + E + E E+++
Sbjct: 392 IREQEEKIREQEEMMQEQ---EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 336 --EEEELEEEEEVLEENEQR-GEE 356
+EE++ E+EE+++E E++ GE+
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQ 472
Score = 52.8 bits (125), Expect = 6e-07
Identities = 42/190 (22%), Positives = 91/190 (47%), Gaps = 29/190 (15%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGF 253
+ ++ E M +QEK+ Q+E + ++ E + + + W +E +
Sbjct: 346 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA----------KMWRQEEKIR-- 393
Query: 254 VQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEE---EYDQEVCDAKE-ASEEEEEVED 309
EE +++E+EEK + EE E ++E+ + +E +EE++ +
Sbjct: 394 ----------EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE 443
Query: 310 EEEEVEDEEEEEVEEAEYVEEGEEELEEEE---LEEEEEVLEENEQRGEEFHLPLEMPLS 366
+E+++ ++EE+ E+ E ++E EE++ E+E E+E ++ E+ E+ + E
Sbjct: 444 QEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKK 503
Query: 367 IFVEAEEKRE 376
I + E+ RE
Sbjct: 504 IREQEEKIRE 513
Score = 50.8 bits (120), Expect = 2e-06
Identities = 40/181 (22%), Positives = 86/181 (47%), Gaps = 18/181 (9%)
Query: 202 RQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAF 261
RQ+EK+ Q+E +R Q+ + + ++ W +E + Q
Sbjct: 387 RQEEKIREQEEKIREQEEMMQEQEEKMGEQ--------EEKMWEQEEEM----QEQEEKM 434
Query: 262 SPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS---EEEEEVEDEEEEVEDEE 318
E+ + + E+EE+ + +E +QE ++ E+E +++++EE++ +E
Sbjct: 435 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE 494
Query: 319 EEEVEEAEYVEEGEEELEEEE---LEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKR 375
E+ E+ + + E EE++ E+E E+EE++ E+ E+ E+ E + + E+ R
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMR 554
Query: 376 E 376
E
Sbjct: 555 E 555
Score = 47.8 bits (112), Expect = 2e-05
Identities = 44/191 (23%), Positives = 88/191 (46%), Gaps = 19/191 (9%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E +R+QE+ +++E +R Q+ EA R +E QE + +Q
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE---QEEKIREQEEM---MQEQE 410
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEE--EYDQEVCDAKEASEEEEEVEDEEEEVED 316
E+ + E+EE+ + +E+ E ++++ + +E E+EE+ E+EE
Sbjct: 411 EKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMG 470
Query: 317 EEEEEV--------EEAEYVEEGEEELEEEEL---EEEEEVLEENEQRGEEFHLPLEMPL 365
E+E ++ E+ E + EE++ E+E E+EE++ E+ E E+ E
Sbjct: 471 EQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 530
Query: 366 SIFVEAEEKRE 376
+ + E+ +E
Sbjct: 531 KMCEQEEKMQE 541
Score = 46.6 bits (109), Expect = 4e-05
Identities = 34/120 (28%), Positives = 63/120 (52%), Gaps = 17/120 (14%)
Query: 254 VQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDE--EEYDQEVCDAKEASEEEEEVEDEE 311
+Q+ S EEN+ L ++EE+ +E +E ++++ + +E E+EE +
Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321
Query: 312 EEVEDEEEEEV--------EEAEYVEEGEEEL-------EEEELEEEEEVLEENEQRGEE 356
EE+ E+EE++ E+ E + E EE++ E+EE +EEE + E E+R E+
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 381
Score = 44.7 bits (104), Expect = 2e-04
Identities = 31/113 (27%), Positives = 63/113 (55%), Gaps = 7/113 (6%)
Query: 266 EENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEA 325
+E QS++ L + EE + + QE ++ +EE++++ EE+++++EE+ E+
Sbjct: 260 KELQSVSAKLQAQVEENELWNRLNQQQE----EKMWRQEEKIQEREEKIQEQEEKIREQE 315
Query: 326 EYVEEGEEEL--EEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRE 376
E + EE + +EE++ +EE++ E E++ E + I E EEKR+
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI-REQEEKRQ 367
Score = 35.0 bits (79), Expect = 0.12
Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 13/178 (7%)
Query: 203 QQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFS 262
Q++K +R E L ++ +S E + + +K LQE L V++
Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK----LQEKLQ-LVESEKSEIQ 229
Query: 263 PNPEENQ---SLAPLLVEEEEEKKNDDEEEYDQEVCDAK-EASEEEEEVEDEEEEVEDEE 318
N +E + A LL+ +++ + D + + AK +A EE E+ + + +E
Sbjct: 230 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ--QQE 287
Query: 319 EEEVEEAEYVEEGEEELEEEE--LEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEK 374
E+ + E ++E EE+++E+E + E+EE + E+ E + + E EEK
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 345
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 62.0 bits (149), Expect = 9e-10
Identities = 52/186 (27%), Positives = 93/186 (50%), Gaps = 30/186 (16%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E MR+Q+K+ +Q+E +R +K T E K+TW +E + +
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQE----------------KKTWDQEEKMREEERMRE 564
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEE---EYDQEVCDAKEASEEEEEV--EDEEEE 313
EE ++ E+EEK + EE E ++++ + +E +E+EE E EE+
Sbjct: 565 REKKMREEEE------MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618
Query: 314 VEDEEEEEVEEAEYVE-EGEEELEEEE--LEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
E EEE++++E E + E EE+++E+E + E+EE + E E++ E ++ E
Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRE 678
Query: 371 AEEKRE 376
EEK +
Sbjct: 679 QEEKMQ 684
Score = 55.8 bits (133), Expect = 7e-08
Identities = 39/157 (24%), Positives = 81/157 (51%), Gaps = 14/157 (8%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E+M QEK +QE +R Q+ + + R ++ W +E ++ Q+
Sbjct: 466 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ--------EQKMWDQEERMWE--QDER 515
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
L E + + +EE+ ++ +E +++ D +E EEE + + E+++ +EE
Sbjct: 516 LR--EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 573
Query: 319 EEEVEEAEYVEEGEEEL--EEEELEEEEEVLEENEQR 353
E E+ E ++E EE++ +EE++ E+EE ++E E++
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
Score = 54.3 bits (129), Expect = 2e-07
Identities = 41/158 (25%), Positives = 78/158 (49%), Gaps = 9/158 (5%)
Query: 202 RQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAF 261
+Q+EK+ RQ+E LR Q+ + + R ++ L+E + L
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL----REQEKELREQEKELREQKKLR- 306
Query: 262 SPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVC---DAKEASEEEEEVEDEEEEVEDEE 318
E+ Q + E+EE+ + +E+ + QE K+ E+E+++ D+EE + +++
Sbjct: 307 -EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 365
Query: 319 EEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEE 356
E E+ E + E E+ E+EE +EEE + E E++ E
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403
Score = 52.0 bits (123), Expect = 1e-06
Identities = 44/164 (26%), Positives = 80/164 (48%), Gaps = 28/164 (17%)
Query: 199 EDMRQQEKVERQQEAL-RAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNP 257
E MR++EK R++E + R Q+ + + R ++ W +E +
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQ--------EEKMWEQEEKM------- 604
Query: 258 SLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDE 317
E+ + E+EEE K ++EE + + +E +E+EE E+EE E
Sbjct: 605 ----QEQEEKMWEQEEKMWEQEEEDKMQEQEEM---MWEQEEKMQEQEEKMWEQEEKMRE 657
Query: 318 EEEEVEEAEYVEEGEEEL---EEEELEEEEEVLEENEQ--RGEE 356
+EE++ E E +G+EE +EE+++ +EE + E E+ RG+E
Sbjct: 658 QEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE 701
Score = 51.2 bits (121), Expect = 2e-06
Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 11/172 (6%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGF 253
M + E MR+QEK R+QE ++ E R + ++ W +E +
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQ-EEQMQEQEEKMWEQEEKMREQ 329
Query: 254 VQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEE---EYDQEVCDAKEASEEEEEVEDE 310
+ EE + E+E+K D EE E D+ + + +E E+E++ ++
Sbjct: 330 EEK-----MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 384
Query: 311 EEEVEDEEEEEVEEAEYVEEGE--EELEEEELEEEEEVLEENEQRGEEFHLP 360
EE++++EE E + EE E E EE+ ++EE + E+ E+ ++ LP
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
Score = 50.4 bits (119), Expect = 3e-06
Identities = 40/159 (25%), Positives = 80/159 (50%), Gaps = 25/159 (15%)
Query: 199 EDMRQQE-KVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNP 257
E MR+QE K+ RQ+E L Q+ + + R + W E L
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ--------EERMWEQDERL------- 368
Query: 258 SLAFSPNPEENQSLAPLLVEEEEEKKNDDEE--EYDQEVCDAKEAS-EEEEEVEDEEEEV 314
+E + + E+EEK ++E E ++++ + +E E+EE+++ +EE +
Sbjct: 369 ------REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422
Query: 315 EDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQR 353
++EE+E ++ E+ E+ E+E+++E+EE + E E++
Sbjct: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Score = 49.7 bits (117), Expect = 5e-06
Identities = 40/169 (23%), Positives = 88/169 (52%), Gaps = 28/169 (16%)
Query: 194 MNQIYEDMRQQE-KVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYG 252
M + E MR+QE K++ Q+E +R Q+ + + + ++ W +E ++
Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ--------EEKMWEQEEKMW- 619
Query: 253 FVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEE-YDQEVCDAKEASEEEEEVEDEE 311
E+ ++ E+EEK + EE+ ++QE ++ E+EE++ ++E
Sbjct: 620 ---------EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE----EKMREQEEKMREQE 666
Query: 312 EEVEDEEEEEVEEAEYVEEGEEEL--EEEELEEEEEVL--EENEQRGEE 356
E+++ +EE+ E+ E ++ EE++ +EE++ +EE + +E + G+E
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQE 715
Score = 49.3 bits (116), Expect = 6e-06
Identities = 42/203 (20%), Positives = 94/203 (46%), Gaps = 32/203 (15%)
Query: 194 MNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGN----DAPPGGSKETWGLQET 249
M + E+M +QE+ E QQ+ L QK + + + +E WG ++
Sbjct: 415 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
Query: 250 LYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQE---------VCDAKEA 300
++ E+ + + E+EE+ ++ +++ +DQE + + +E
Sbjct: 475 MW------------RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522
Query: 301 SEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEE-------ELEEEEEVLEENEQR 353
E++++ +EE++ +E++ + +E + ++ E+ EEE ++ EEEE++ E E++
Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582
Query: 354 GEEFHLPLEMPLSIFVEAEEKRE 376
+E + E EEK +
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQ 605
Score = 45.4 bits (106), Expect = 9e-05
Identities = 43/183 (23%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
+++R+QEK R+Q+ LR Q+ + E + ++ W +E L+ Q
Sbjct: 290 KELREQEKELREQKKLREQEEQMQ-EQEEKMWEQEEKMREQEEKMWRQEERLWE--QEKQ 346
Query: 259 LAFSP----NPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEE- 313
+ + EE + E+EE+ + E+ ++QE E +EEE + + E++
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQE-----EKMQEEERIREREKKM 401
Query: 314 VEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEE 373
E+EE +E + ++ E E+EE E +++ L E +++ E E I+ + E+
Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 374 KRE 376
R+
Sbjct: 462 IRD 464
Score = 43.1 bits (100), Expect = 4e-04
Identities = 23/80 (28%), Positives = 52/80 (65%), Gaps = 5/80 (6%)
Query: 275 LVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEE 334
L E+E++ + +E+ + QE + E+E ++ ++EE++ +E+ E+ + + E E+E
Sbjct: 243 LREQEKKIRKQEEKMWRQE----ERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 335 L-EEEELEEEEEVLEENEQR 353
L E+++L E+EE ++E E++
Sbjct: 299 LREQKKLREQEEQMQEQEEK 318
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/170 (22%), Positives = 78/170 (45%), Gaps = 19/170 (11%)
Query: 194 MNQIYEDMRQQE-KVERQQEALRAQKATV-SGEASPARSSGNDAPPGGSKETWGLQETLY 251
M + E MR+QE K+ Q+E ++ Q+ + E D + W +E +
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642
Query: 252 GFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASE----EEEEV 307
EE + E+EEK + EE+ + +E E +EE++
Sbjct: 643 ------------EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 308 EDEEEEVEDEEEEEVEEAEYVEEGEEEL-EEEELEEEEEVLEENEQRGEE 356
++EE++ +EE+ + E + EE++ +EE+ E+EE + + +++ +E
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQE 740
Score = 40.0 bits (92), Expect = 0.004
Identities = 28/101 (27%), Positives = 56/101 (55%), Gaps = 8/101 (7%)
Query: 279 EEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEE 338
+EE +EE +QE K+ ++EE++ +EE + ++E + E+ E + E+ L E+
Sbjct: 233 QEEMWRQEEELREQE----KKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQ 288
Query: 339 ELE---EEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRE 376
E E +E+E+ E+ + R +E + E ++ + E+ RE
Sbjct: 289 EKELREQEKELREQKKLREQEEQMQ-EQEEKMWEQEEKMRE 328
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 8/78 (10%)
Query: 279 EEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEE 338
EEE+ ++EE K +EE E EE+E + + E +E + +E +E EE+
Sbjct: 403 EEEETMREQEE--------KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
Query: 339 ELEEEEEVLEENEQRGEE 356
E+EE++ ++ E G+E
Sbjct: 455 IWEQEEKIRDQEEMWGQE 472
Score = 38.5 bits (88), Expect = 0.011
Identities = 21/82 (25%), Positives = 52/82 (63%), Gaps = 2/82 (2%)
Query: 277 EEEEEKKNDDEEEYDQEVCD-AKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEEL 335
E+EE+ + +E ++QE + ++ E++E E+E+++++EE+ E+ E + + EE
Sbjct: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469
Query: 336 -EEEELEEEEEVLEENEQRGEE 356
+E+++ +E++ E+ +Q E+
Sbjct: 470 GQEKKMWRQEKMREQEDQMWEQ 491
Score = 35.4 bits (80), Expect = 0.093
Identities = 24/86 (27%), Positives = 49/86 (56%), Gaps = 11/86 (12%)
Query: 276 VEEEEEKKNDDEEEYDQEVCDAKEASE----EEEEVEDEEEEVEDEEEEEVEEAEYVEEG 331
+ ++EEK EE ++ +E E +E+ + ++E+E+ E+E+E+ E + + E
Sbjct: 250 IRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR-EQEKELREQKKLREQ 308
Query: 332 EEELEEEELE----EEEEVLEENEQR 353
EE++ +E E E+EE + E E++
Sbjct: 309 EEQM--QEQEEKMWEQEEKMREQEEK 332
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 62.0 bits (149), Expect = 9e-10
Identities = 37/104 (35%), Positives = 59/104 (56%), Gaps = 8/104 (7%)
Query: 254 VQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEE 313
V+N F+P+P E +S E+EE D+++E + +K+ + + E +E
Sbjct: 322 VRNIIFPFAPSPNEEES------EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKE 375
Query: 314 VEDEEEEEVEEAEYVEEGEEELEEE--ELEEEEEVLEENEQRGE 355
E+EE ++ EE + EE EEE EEE + EEEEE+ +NE+ GE
Sbjct: 376 KEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGE 419
Score = 48.9 bits (115), Expect = 8e-06
Identities = 31/79 (39%), Positives = 46/79 (58%), Gaps = 10/79 (12%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEE-----EEEVEDEEEEVEDEE-----EEEVEEAE 326
+EEE KK +++EE ++E KE EE EEE E ++EE EDE+ E E ++
Sbjct: 383 KEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDP 442
Query: 327 YVEEGEEELEEEELEEEEE 345
EE E+EEE L+E ++
Sbjct: 443 GTEETYGEVEEEPLDEAQD 461
Score = 47.4 bits (111), Expect = 2e-05
Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 5/89 (5%)
Query: 278 EEEEKKNDDEEEYDQEVCDAKEASEEEEEVE----DEEEEVEDEEEEEVEEAEYVEEGEE 333
++E K+ ++EE +E KE EEEEE E +EEEE+ ++ EEE E + +E E+
Sbjct: 370 QQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDED 429
Query: 334 ELEEEELEEEEEVLEENEQRGEEFHLPLE 362
++ E E +++ E E GE PL+
Sbjct: 430 GGQKPEGEPQQDPGTE-ETYGEVEEEPLD 457
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 8/80 (10%)
Query: 276 VEEEEEKKNDDEEEYDQEVCDAKEASEEEEEV--EDEEEEVEDEEEEEVEEAEYVEEGEE 333
+++EEE K +E+E ++E + + EEEEE+ ++EEE +EE+E E+ EGE
Sbjct: 381 MKKEEEMKKKEEKEEEEE--EEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEP 438
Query: 334 E----LEEEELEEEEEVLEE 349
+ EE E EEE L+E
Sbjct: 439 QQDPGTEETYGEVEEEPLDE 458
Score = 44.3 bits (103), Expect = 2e-04
Identities = 25/73 (34%), Positives = 45/73 (61%), Gaps = 1/73 (1%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEV-EEAEYVEEGEEEL 335
EEEE K+ ++EEE + + E+ +EE+E ED ++ E E +++ E Y E EE L
Sbjct: 397 EEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPL 456
Query: 336 EEEELEEEEEVLE 348
+E + ++ +E++E
Sbjct: 457 DEAQDDDLDELME 469
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 61.2 bits (147), Expect = 2e-09
Identities = 50/135 (37%), Positives = 69/135 (51%), Gaps = 15/135 (11%)
Query: 220 TVSGEASPARSSG--NDAPPGGSKETWGLQETLYGFVQNPSLA-FSPNPEENQSLA--PL 274
TV+G+ S +R G NDA QE+ ++ SL F +SL PL
Sbjct: 49 TVTGDGSDSRDGGFPNDASTENRSSD---QESASEDIELESLEDFEHFLMSGESLFHYPL 105
Query: 275 LVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEE 334
+ EEE E++ +DEE + E EEEEE E+EEEE E+EEEEE E+ +G
Sbjct: 106 VGEEETEREEEDEEIQE-------EGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGG 158
Query: 335 LEEEELEEEEEVLEE 349
E+ EE++ LEE
Sbjct: 159 NHEQYSLEEDQALEE 173
Score = 50.4 bits (119), Expect = 3e-06
Identities = 29/71 (40%), Positives = 42/71 (59%)
Query: 302 EEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPL 361
EEE E E+E+EE+++E EE EE E EE EEE EEEE E+ + + E++ L
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEE 167
Query: 362 EMPLSIFVEAE 372
+ L +V +E
Sbjct: 168 DQALEEWVSSE 178
Score = 43.1 bits (100), Expect = 4e-04
Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 22/89 (24%)
Query: 281 EKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEV-------------EDEEEEEVEEAEY 327
E ++ D+E +++ E E +ED E + E+E E E E+ E
Sbjct: 69 ENRSSDQESASEDI--------ELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEI 120
Query: 328 VEEGEEELEEEELEEEEEVLEENEQRGEE 356
EEG EE EEEE EEEEE EE E+ E+
Sbjct: 121 QEEGGEEEEEEE-EEEEEEEEEEEEEEEQ 148
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 61.2 bits (147), Expect = 2e-09
Identities = 47/122 (38%), Positives = 59/122 (48%), Gaps = 23/122 (18%)
Query: 269 QSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS---------------EEEEEVEDEEEE 313
+ L +L E EK+ DDE E + A EA+ E+EEE E EEEE
Sbjct: 172 RKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEE 231
Query: 314 VEDEEEEEVEEAEYVEEGEE--------ELEEEELEEEEEVLEENEQRGEEFHLPLEMPL 365
++EEEEE EE EEGEE E EEEE EEEEE EE + +E + P
Sbjct: 232 EKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPT 291
Query: 366 SI 367
+
Sbjct: 292 GV 293
Score = 54.3 bits (129), Expect = 2e-07
Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 9/91 (9%)
Query: 266 EENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEA 325
E + A ++V E+EE++ +EEE E EEEEE E+E E EE E
Sbjct: 208 EAAAAAAEVIVVEDEEEEEKEEEE---------EKEEEEEEGEEEGGGEEGEEGGGGGEG 258
Query: 326 EYVEEGEEELEEEELEEEEEVLEENEQRGEE 356
E EE EEE EEEE EE+ + +E ++R ++
Sbjct: 259 EETEEEEEEEEEEEEEEQIKAFQEKQKRWQQ 289
Score = 42.4 bits (98), Expect = 8e-04
Identities = 26/91 (28%), Positives = 48/91 (52%), Gaps = 15/91 (16%)
Query: 274 LLVEEEEEKKNDDEEEYDQEVCDAKE---------------ASEEEEEVEDEEEEVEDEE 318
++VE+EEE++ ++EEE ++E + +E E EEE E+EEEE E+E+
Sbjct: 217 IVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQ 276
Query: 319 EEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
+ +E + + + L E + +LE+
Sbjct: 277 IKAFQEKQKRWQQPTGVRSWRLREMKPLLEQ 307
>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member A [Homo sapiens]
Length = 249
Score = 60.5 bits (145), Expect = 3e-09
Identities = 34/81 (41%), Positives = 53/81 (65%), Gaps = 4/81 (4%)
Query: 279 EEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEE 338
++E++++DEEEYD++ ++ +E+EE E EEE+V EEEE+ EE E ++E +EE
Sbjct: 168 DDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED-EEGYNDGEVDDEEDEE 226
Query: 339 ELEEEE---EVLEENEQRGEE 356
EL EEE + E E GE+
Sbjct: 227 ELGEEERGQKRKREPEDEGED 247
Score = 51.6 bits (122), Expect = 1e-06
Identities = 32/79 (40%), Positives = 46/79 (58%), Gaps = 6/79 (7%)
Query: 278 EEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEE 337
+++E + D E Y E D +E E+EEE +++ + VEDEE+E+ E EEGEEE
Sbjct: 151 DDKEAPDSDAEGY-VEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEE-----EEGEEEDVS 204
Query: 338 EELEEEEEVLEENEQRGEE 356
E EE+EE + E EE
Sbjct: 205 GEEEEDEEGYNDGEVDDEE 223
Score = 50.1 bits (118), Expect = 4e-06
Identities = 29/65 (44%), Positives = 41/65 (63%), Gaps = 2/65 (3%)
Query: 296 DAKEASEEEEE--VEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQR 353
D KEA + + E VE ++E EDE+EEE +E V E EE+ +EEE EEE+V E E+
Sbjct: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
Query: 354 GEEFH 358
E ++
Sbjct: 211 EEGYN 215
Score = 45.8 bits (107), Expect = 7e-05
Identities = 30/64 (46%), Positives = 44/64 (68%), Gaps = 4/64 (6%)
Query: 290 YDQEVCDAKEASEEE--EEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVL 347
YD++ +A ++ E E ++DEEE+ EDEEE + E+A+ VE+ E+E EEEE EEE+
Sbjct: 148 YDRDDKEAPDSDAEGYVEGLDDEEED-EDEEEYD-EDAQVVEDEEDEDEEEEGEEEDVSG 205
Query: 348 EENE 351
EE E
Sbjct: 206 EEEE 209
Score = 43.1 bits (100), Expect = 4e-04
Identities = 22/69 (31%), Positives = 41/69 (59%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE 336
+E+ + D+E+E ++E + ++ S EEEE E+ + E ++EE+ EE E G++
Sbjct: 180 DEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKR 239
Query: 337 EEELEEEEE 345
E E E E++
Sbjct: 240 EPEDEGEDD 248
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 60.5 bits (145), Expect = 3e-09
Identities = 36/69 (52%), Positives = 45/69 (65%), Gaps = 2/69 (2%)
Query: 299 EASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFH 358
E EEEE EDEEEE E+E+EEE EE E EE +E E+EE EEEE E E+ EE
Sbjct: 1869 EVFTEEEEEEDEEEEGEEEDEEEKEEDE--EETAQEKEDEEKEEEEAAEGEKEEGLEEGL 1926
Query: 359 LPLEMPLSI 367
L +++P S+
Sbjct: 1927 LQMKLPESV 1935
Score = 54.7 bits (130), Expect = 1e-07
Identities = 61/201 (30%), Positives = 86/201 (42%), Gaps = 28/201 (13%)
Query: 136 PPGRKKRWGRRGRGLRHHPRHSYPRSPPADVSTLPRPVKLYEWREPGMRAPPNTTQFIMN 195
PPGR G HPRH P V+T RP P +PP +
Sbjct: 1748 PPGRSTENG--------HPRHGLPG---VGVTTSLRP--------PHHFSPPCFVAALPA 1788
Query: 196 QIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDA--PPGGSKETWGLQETLYGF 253
+ + EALR + + GEA R G A P GGS E + +
Sbjct: 1789 AGAAEAPARLSPAIPLEALRDKALRMLGEA--VRDGGQHARDPVGGSVEFQFVP--VLKL 1844
Query: 254 VQNPSLAFSPNPEENQSLAPLLVEE---EEEKKNDDEEEYDQEVCDAKEASEEEEEVEDE 310
V + E+ + + ++ E EEE++ D+EEE ++E + KE EEE E E
Sbjct: 1845 VSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKE 1904
Query: 311 EEEVEDEEEEEVEEAEYVEEG 331
+EE E+EE E E+ E +EEG
Sbjct: 1905 DEEKEEEEAAEGEKEEGLEEG 1925
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 60.5 bits (145), Expect = 3e-09
Identities = 36/69 (52%), Positives = 45/69 (65%), Gaps = 2/69 (2%)
Query: 299 EASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFH 358
E EEEE EDEEEE E+E+EEE EE E EE +E E+EE EEEE E E+ EE
Sbjct: 1869 EVFTEEEEEEDEEEEGEEEDEEEKEEDE--EETAQEKEDEEKEEEEAAEGEKEEGLEEGL 1926
Query: 359 LPLEMPLSI 367
L +++P S+
Sbjct: 1927 LQMKLPESV 1935
Score = 54.7 bits (130), Expect = 1e-07
Identities = 61/201 (30%), Positives = 86/201 (42%), Gaps = 28/201 (13%)
Query: 136 PPGRKKRWGRRGRGLRHHPRHSYPRSPPADVSTLPRPVKLYEWREPGMRAPPNTTQFIMN 195
PPGR G HPRH P V+T RP P +PP +
Sbjct: 1748 PPGRSTENG--------HPRHGLPG---VGVTTSLRP--------PHHFSPPCFVAALPA 1788
Query: 196 QIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDA--PPGGSKETWGLQETLYGF 253
+ + EALR + + GEA R G A P GGS E + +
Sbjct: 1789 AGAAEAPARLSPAIPLEALRDKALRMLGEA--VRDGGQHARDPVGGSVEFQFVP--VLKL 1844
Query: 254 VQNPSLAFSPNPEENQSLAPLLVEE---EEEKKNDDEEEYDQEVCDAKEASEEEEEVEDE 310
V + E+ + + ++ E EEE++ D+EEE ++E + KE EEE E E
Sbjct: 1845 VSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKE 1904
Query: 311 EEEVEDEEEEEVEEAEYVEEG 331
+EE E+EE E E+ E +EEG
Sbjct: 1905 DEEKEEEEAAEGEKEEGLEEG 1925
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 60.5 bits (145), Expect = 3e-09
Identities = 42/98 (42%), Positives = 53/98 (54%), Gaps = 5/98 (5%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE 336
+EE E K + E E + E A E SE EEE E EEE +EE E+ + E E+ EEE+E
Sbjct: 78 KEEAEVKVEQEREIESE---AGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
Query: 337 -EEELEEEEEVLEENEQRGE-EFHLPLEMPLSIFVEAE 372
E+E E EE+ EE E E E E I +EAE
Sbjct: 135 DEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAE 172
Score = 56.6 bits (135), Expect = 4e-08
Identities = 37/93 (39%), Positives = 50/93 (53%), Gaps = 5/93 (5%)
Query: 272 APLLVEEEEEKKND-DEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEE 330
A + VE+E E +++ EE +E +++E SE EEE EDE DEE EE E E +E
Sbjct: 81 AEVKVEQEREIESEAGEESESEEESESEEESETEEESEDE----SDEESEEDSEEEMEDE 136
Query: 331 GEEELEEEELEEEEEVLEENEQRGEEFHLPLEM 363
E E EE+ EE E E + EF +EM
Sbjct: 137 QESEAEEDNQEEGESEAEGETEAESEFDPEIEM 169
Score = 52.8 bits (125), Expect = 6e-07
Identities = 34/81 (41%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Query: 266 EENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEA 325
EE++S EEE E + + E+E D+E ++E SEEE E E E E ED +EE EA
Sbjct: 97 EESESEEESESEEESETEEESEDESDEE---SEEDSEEEMEDEQESEAEEDNQEEGESEA 153
Query: 326 EYVEEGEEELEEEELEEEEEV 346
E E E E + E E E V
Sbjct: 154 EGETEAESEFDPEIEMEAERV 174
Score = 49.7 bits (117), Expect = 5e-06
Identities = 30/72 (41%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 286 DEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEE-ELEEEE 344
D E +E + K E E E E EE +EE E EE+E EE E+E +EE E + EE
Sbjct: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEE 131
Query: 345 EVLEENEQRGEE 356
E+ +E E EE
Sbjct: 132 EMEDEQESEAEE 143
Score = 42.0 bits (97), Expect = 0.001
Identities = 34/82 (41%), Positives = 44/82 (53%), Gaps = 8/82 (9%)
Query: 296 DAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEE-ELEEEEEVLEENEQRG 354
D + A +EE EV+ E+E + E E EE+E EE E E E E E E E+E EE+E+
Sbjct: 72 DGEGAGKEEAEVKVEQER--EIESEAGEESESEEESESEEESETEEESEDESDEESEEDS 129
Query: 355 EEFHLPLEMPLSIFVEAEEKRE 376
EE EM EAEE +
Sbjct: 130 EE-----EMEDEQESEAEEDNQ 146
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 59.7 bits (143), Expect = 5e-09
Identities = 35/89 (39%), Positives = 57/89 (64%), Gaps = 8/89 (8%)
Query: 268 NQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEY 327
++ + LL E E+++ EEE ++E +E EEEEV +EEEE ++EEE E ++ E
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEERE----EEEEREEEEVREEEEERKEEEEGEEKQVEK 2282
Query: 328 VEEGEE----ELEEEELEEEEEVLEENEQ 352
EE ++ E ++EE++E+EEV EE E+
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEEVFEEKEE 2311
Score = 59.7 bits (143), Expect = 5e-09
Identities = 38/108 (35%), Positives = 64/108 (59%), Gaps = 4/108 (3%)
Query: 275 LVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEA---EYVEEG 331
L EEEE++ ++EE ++EV + +E +EEEE E+++ E E+EE+++ ++ E V+E
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK 2302
Query: 332 EEELEE-EELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENF 378
EE EE EE+ EEE +++ EE LE + E +K + F
Sbjct: 2303 EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQF 2350
Score = 58.9 bits (141), Expect = 8e-09
Identities = 38/115 (33%), Positives = 65/115 (56%), Gaps = 4/115 (3%)
Query: 266 EENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEE--VEDEEEEVEDEEEEEVE 323
EE +SL L ++E ++EE ++E + +E EEEEE E+E EE + E+EEE +
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK 2287
Query: 324 EAEYVEEGEEELEEEE--LEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRE 376
+ + E+ +EE++E+E EE+EE++ E E E S+ E + ++E
Sbjct: 2288 KKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
Score = 53.9 bits (128), Expect = 3e-07
Identities = 33/89 (37%), Positives = 52/89 (58%), Gaps = 12/89 (13%)
Query: 266 EENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEV--EDEEEEVEDEEEEEVE 323
EE + + +EEEEKK +E+ +EV + +E EE+EE+ E+E E + DEEEEE
Sbjct: 2271 EEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEE-- 2328
Query: 324 EAEYVEEGEEELEEEELEEEEEVLEENEQ 352
E EEE++ E+E+L++ +Q
Sbjct: 2329 --------ESCSLEEEVDREKEILKKEKQ 2349
Score = 47.0 bits (110), Expect = 3e-05
Identities = 41/139 (29%), Positives = 65/139 (46%), Gaps = 9/139 (6%)
Query: 267 ENQSLAPLLV----EEEEEKKNDD-EEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEE 321
E + + P L + +E K+ D +E++ +V + + EE+E +E+E +E
Sbjct: 2185 EEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLS 2244
Query: 322 VEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFISC 381
EE E E EEE EEE EEE + E+ GEE + E + E+K+E
Sbjct: 2245 SEEEE--EREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK 2302
Query: 382 --TFLNPEQIIPKVPQESL 398
F E+I+ + ESL
Sbjct: 2303 EEVFEEKEEIMSEEETESL 2321
Score = 43.1 bits (100), Expect = 4e-04
Identities = 27/109 (24%), Positives = 55/109 (50%), Gaps = 8/109 (7%)
Query: 274 LLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDE--------EEEEVEEA 325
+L + +E++ DEEE E ++E E+E++V +E+ +++E + E+
Sbjct: 1528 MLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKK 1587
Query: 326 EYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEK 374
EE + EEE+L +EE L + E++ + ++ + +AE K
Sbjct: 1588 RAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGK 1636
Score = 42.4 bits (98), Expect = 8e-04
Identities = 32/96 (33%), Positives = 55/96 (57%), Gaps = 8/96 (8%)
Query: 266 EENQSLAPLLVEEEEEKKNDD--EEEYDQEV----CDAKEASEEEEEVEDEEEEVEDEEE 319
E LA + E + ++N D E+E QE+ D +E S +EEE+ EE ++ +E++
Sbjct: 1688 EVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKK 1747
Query: 320 EEVEEAEYVEEGEEELEEEE--LEEEEEVLEENEQR 353
+ EE E + E+L EEE L +EEE+L + +++
Sbjct: 1748 KLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEK 1783
Score = 40.0 bits (92), Expect = 0.004
Identities = 30/109 (27%), Positives = 61/109 (55%), Gaps = 12/109 (11%)
Query: 276 VEEEEEKKNDDEEEYDQE----VCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEG 331
+E + E+ + EEE +QE V + K+ +EEEE + + E++ +EE + +E E + +
Sbjct: 1721 LEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQE 1780
Query: 332 EEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFIS 380
+E+L + +E++ EE E+ G + +E + + +KRE +I+
Sbjct: 1781 KEKL----AQHKEKMPEEEERLGRKREQLIEKKMKL----AQKRERWIN 1821
Score = 38.1 bits (87), Expect = 0.014
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 22/123 (17%)
Query: 241 KETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEE-----KKNDDEEEYDQEVC 295
K+ W + ++G + A+ E+ L++EEE+ +K EEE QE
Sbjct: 1461 KKAWDEWKQVHGETRKSWKAWKEEWEKR------LLQEEEKLHQAGEKLSPEEEMLQE-- 1512
Query: 296 DAKEASEEEEEV-------EDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLE 348
D K EE ++V + +E++ +DEEE +EE E EGEE+ E++ EE+ + E
Sbjct: 1513 DKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEE-EVSREGEEK-EQQVTEEQRHIQE 1570
Query: 349 ENE 351
E++
Sbjct: 1571 EHK 1573
Score = 36.2 bits (82), Expect = 0.055
Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 16/93 (17%)
Query: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEV---------EEAEY 327
+EE EK+ EEE ++ A E EEE+ E+++++ EE ++V +E +Y
Sbjct: 1482 KEEWEKRLLQEEE---KLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQY 1538
Query: 328 VEEGEEELEEEEL----EEEEEVLEENEQRGEE 356
+E E LEEE E+E++V EE EE
Sbjct: 1539 KDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEE 1571
Score = 33.9 bits (76), Expect = 0.27
Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 12/121 (9%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E+ ++E+ ER++E +R ++ E K+ +E VQ
Sbjct: 2247 EEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKK---KEKKKEEVQEKE 2303
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318
F E ++ EEE E +D+EEE +E C +E + E+E+ +E++ + +E
Sbjct: 2304 EVFEEKEE-------IMSEEETESLSDEEEE--EESCSLEEEVDREKEILKKEKQFKLQE 2354
Query: 319 E 319
+
Sbjct: 2355 Q 2355
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 2/130 (1%)
Query: 275 LVEEEEEKKNDDEEEYDQ--EVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGE 332
L EEE + D + ++++ +V + +S+ +E+ +EEEV EEE E E ++
Sbjct: 1503 LSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVT 1562
Query: 333 EELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEEKRENFISCTFLNPEQIIPK 392
EE + E + + R E+ E L+ E + E ++ Q K
Sbjct: 1563 EEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVK 1622
Query: 393 VPQESLFMAQ 402
+ Q+ MAQ
Sbjct: 1623 ITQDDREMAQ 1632
Score = 28.9 bits (63), Expect = 8.7
Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 296 DAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQ-RG 354
D K+A +E ++V E + +EE E+ EE + E+L EEE+L+E+++ +
Sbjct: 1459 DWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKW 1518
Query: 355 EEFHLPLEMPLS 366
EE+ E LS
Sbjct: 1519 EEWKQVWENMLS 1530
Score = 28.9 bits (63), Expect = 8.7
Identities = 38/167 (22%), Positives = 73/167 (43%), Gaps = 25/167 (14%)
Query: 196 QIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQET--LYGF 253
Q++E+M + E+Q + ++ T+ E S G + ++E +QE
Sbjct: 1523 QVWENMLSSKSKEQQYKD--EEEVTLEEEVS---REGEEKEQQVTEEQRHIQEEHKWARI 1577
Query: 254 VQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQE-----------VCDAKEASE 302
+ + A +E + LA +EEEK +E + QE D +E ++
Sbjct: 1578 HRKRARAEKKRAQEERKLA-----QEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQ 1632
Query: 303 EEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEE--EELEEEEEVL 347
E + +EE + E+ +EAE + + ++L + E++ EEE L
Sbjct: 1633 AEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKL 1679
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 59.7 bits (143), Expect = 5e-09
Identities = 44/185 (23%), Positives = 86/185 (46%), Gaps = 20/185 (10%)
Query: 174 KLYEWREPGMRAPPNTTQFIMNQIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGN 233
K+ EW E I Q + Q+EK+ Q+E +R Q+ + + R
Sbjct: 369 KIQEWEEK-----------IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ-- 415
Query: 234 DAPPGGSKETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQE 293
+ +E QE + + E + + E+EEK+ ++E+ +QE
Sbjct: 416 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK-----IREQEEKRQEEEKIREQE 470
Query: 294 VCDAKEAS--EEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENE 351
+EA +EE++ ++EE++ ++EE+ + E + E E+ EEE+ +E+EE+ + E
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530
Query: 352 QRGEE 356
+ E+
Sbjct: 531 KIREQ 535
Score = 56.2 bits (134), Expect = 5e-08
Identities = 40/168 (23%), Positives = 82/168 (48%), Gaps = 26/168 (15%)
Query: 199 EDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPS 258
E RQ+EK+ Q+E +R Q+ + + K W +E +
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK-VWRQEEKIR------- 588
Query: 259 LAFSPNPEENQSLAPLLVEEEEEKKNDDEE---EYDQEVCDAKEASEEEEE--------V 307
EE + E+EE + EE E ++++C+ +E +E+EE +
Sbjct: 589 -----EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 308 EDEEEEVEDEEEEEVEEAEYVEEGEEEL--EEEELEEEEEVLEENEQR 353
++E+++ ++EE+ E+ E ++E EE++ +EE++ E+EE ++E E++
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Score = 55.8 bits (133), Expect = 7e-08
Identities = 44/181 (24%), Positives = 88/181 (48%), Gaps = 25/181 (13%)
Query: 196 QIYEDMRQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQ 255
Q E+M +QE+ R+QE + QK + + R ++ W +E ++
Sbjct: 520 QEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ--------EEKMWRQEEKMH---- 567
Query: 256 NPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVE 315
+ EE V +EEK + EE+ ++ ++ E+EE +++EE++
Sbjct: 568 --------DQEEKIREQEEKVWRQEEKIREQEEKIREQ---EEKIREQEEMTQEQEEKMG 616
Query: 316 DEEEEEVEEAEYVEEGEEEL--EEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAEE 373
++EE+ E+ E ++E EE++ +EE++ E+E+ + E E++ E ++ E EE
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 676
Query: 374 K 374
K
Sbjct: 677 K 677
Score = 55.8 bits (133), Expect = 7e-08
Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 26/166 (15%)
Query: 203 QQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFS 262
Q+EKV RQ+E +R Q+ + + R +E QE G
Sbjct: 576 QEEKVWRQEEKIREQEEKIREQEEKIREQ---------EEMTQEQEEKMG---------- 616
Query: 263 PNPEENQSLAPLLVEEEEEKKNDDEE---EYDQEVCDAKEASEEEEE-VEDEEEEVEDEE 318
EE ++E+EEK EE E ++++ + +E E+EE ++++EE++ ++E
Sbjct: 617 -EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
Query: 319 EEEVEEAEYVEEGEEEL--EEEELEEEEEVLEENEQRGEEFHLPLE 362
E+ E+ E ++E EE++ +EE++ E+E L + E++ +E LE
Sbjct: 676 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 54.3 bits (129), Expect = 2e-07
Identities = 41/169 (24%), Positives = 85/169 (50%), Gaps = 18/169 (10%)
Query: 202 RQQEKVERQQEALRAQKATVSGEASPARSSGN---DAPPGGSKETWGLQETLYGFVQNPS 258
RQ+EK+ Q+E +R Q+ + + + +E W +E ++
Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEK----IREQE 536
Query: 259 LAFSPNPEENQSLAPLLVEEE-----EEKKNDDEE---EYDQEVCDAKE-ASEEEEEVED 309
+ + ++ + +EE EEK +D EE E +++V +E E+EE++ +
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE 596
Query: 310 EEEEVEDEEEEEVEEAEYVEEGEEEL--EEEELEEEEEVLEENEQRGEE 356
+EE++ ++EE E+ E + E EE++ +EE+++E+EE + E++ E
Sbjct: 597 QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Score = 52.8 bits (125), Expect = 6e-07
Identities = 38/165 (23%), Positives = 79/165 (47%), Gaps = 25/165 (15%)
Query: 194 MNQIYEDM--RQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLY 251
+NQ E+ RQ+EK++ +E ++ Q+ + + R +E QE +
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ---------EEKMRRQEEMM 405
Query: 252 GFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEE---EYDQEVCDAKEASEEEEEVE 308
EE ++ E+EEK EE E ++++ + +E E+E++
Sbjct: 406 W-----------EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 454
Query: 309 DEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQR 353
++EE+ ++EE+ +E +E + +EE++ E+EE + E E++
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Score = 49.7 bits (117), Expect = 5e-06
Identities = 35/128 (27%), Positives = 71/128 (55%), Gaps = 6/128 (4%)
Query: 254 VQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDE--EEYDQEVCDAKEA-SEEEEEVEDE 310
+Q+ S EEN+ L ++EE+ +E +E+++++ + +E E+EE++ ++
Sbjct: 335 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 394
Query: 311 EEEVEDEEEEEVEEAEYVEEGEEEL--EEEELEEEEEVLEENEQRGEEFHLPLEMPLSIF 368
EE++ +EE E+ E + EE + +EE++ +EE++ E E++ E + I
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI- 453
Query: 369 VEAEEKRE 376
E EEKR+
Sbjct: 454 REQEEKRQ 461
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 11/149 (7%)
Query: 202 RQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAF 261
RQ+EK+ Q+E +R Q+ + + + + G +E QE +Q
Sbjct: 582 RQEEKIREQEEKIREQEEKIREQEEMTQEQ--EEKMGEQEEKMCEQEEK---MQEQEEKM 636
Query: 262 SPNPEENQSLAPLLVEEEEEKKNDDE--EEYDQEVCDAKEASEEEEEVEDEEEEVEDEEE 319
E+ + + E+EE+ + +E +E ++++ + +E E+EE E+EE +E
Sbjct: 637 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Query: 320 EEVEEAEYVEEGEEELEEEELEEEEEVLE 348
E++ E +E +EE+++E +E LE
Sbjct: 697 EKMWE----QEVRLRQQEEKMQEHQEHLE 721
Score = 35.8 bits (81), Expect = 0.071
Identities = 38/157 (24%), Positives = 76/157 (48%), Gaps = 13/157 (8%)
Query: 203 QQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFS 262
Q++K +R E L ++ +S E + + +K LQE L V++
Sbjct: 248 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK----LQEKLQ-LVESEKSEIQ 302
Query: 263 PNPEENQ---SLAPLLVEEEEEKKNDDEEEYDQEVCDAK-EASEEEEEVEDEEEEVEDEE 318
N +E + A LL+ +++ + D + + AK +A EE E+ + + +E
Sbjct: 303 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ--QQE 360
Query: 319 EEEVEEAEYVEEGEEELEEEE--LEEEEEVLEENEQR 353
E+ + E ++E EE+++E+E + E+EE + E E++
Sbjct: 361 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.134 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,516,227
Number of Sequences: 37866
Number of extensions: 1656980
Number of successful extensions: 69515
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1332
Number of HSP's successfully gapped in prelim test: 901
Number of HSP's that attempted gapping in prelim test: 14038
Number of HSP's gapped (non-prelim): 19849
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.