Search of human proteins with 22749257

Search of human proteins with 22749257

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749257 hypothetical protein LOC165100 [Homo sapiens]
         (395 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749257 hypothetical protein LOC165100 [Homo sapiens]             780   0.0  
gi|226442791 runt-related transcription factor 2 isoform b [Homo...    45   1e-04
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    42   7e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    42   0.001
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         42   0.001
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             42   0.001
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  39   0.006
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    39   0.006
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    39   0.006
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    39   0.006
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    39   0.006
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    39   0.006
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    39   0.006
gi|38570099 glutamine-rich 1 [Homo sapiens]                            39   0.006
gi|38570097 glutamine-rich 1 [Homo sapiens]                            39   0.006
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        39   0.011
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    38   0.014
gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2...    38   0.014
gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1...    38   0.014
gi|46243671 G protein-coupled receptor 152 [Homo sapiens]              38   0.014
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    38   0.018
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                38   0.018
gi|226442783 runt-related transcription factor 2 isoform a [Homo...    37   0.024
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    37   0.024
gi|66934969 runt-related transcription factor 2 isoform c [Homo ...    37   0.024
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...    37   0.031
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     37   0.031
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    37   0.031
gi|119709822 castor homolog 1, zinc finger isoform b [Homo sapiens]    37   0.031
gi|57634536 La ribonucleoprotein domain family, member 4B [Homo ...    37   0.041

>gi|22749257 hypothetical protein LOC165100 [Homo sapiens]
          Length = 395

 Score =  780 bits (2013), Expect = 0.0
 Identities = 395/395 (100%), Positives = 395/395 (100%)

Query: 1   MALPGYPLGNVDDSRSKDSPAGEPQGQVPLTADVLAVSSSVASTDWQDIDQASFKTATPR 60
           MALPGYPLGNVDDSRSKDSPAGEPQGQVPLTADVLAVSSSVASTDWQDIDQASFKTATPR
Sbjct: 1   MALPGYPLGNVDDSRSKDSPAGEPQGQVPLTADVLAVSSSVASTDWQDIDQASFKTATPR 60

Query: 61  AISTSGDKDKSAVVPEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQS 120
           AISTSGDKDKSAVVPEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQS
Sbjct: 61  AISTSGDKDKSAVVPEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQS 120

Query: 121 LVVFPSHLLGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANG 180
           LVVFPSHLLGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANG
Sbjct: 121 LVVFPSHLLGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANG 180

Query: 181 QHGPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPA 240
           QHGPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPA
Sbjct: 181 QHGPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPA 240

Query: 241 GSVSPSPGPHEVALGRRPLDPSLYTASEENSYMRSMTSLLDRGEGSISSLADILVWSETT 300
           GSVSPSPGPHEVALGRRPLDPSLYTASEENSYMRSMTSLLDRGEGSISSLADILVWSETT
Sbjct: 241 GSVSPSPGPHEVALGRRPLDPSLYTASEENSYMRSMTSLLDRGEGSISSLADILVWSETT 300

Query: 301 MGMAIATGFLDSGHSTVADLLHSSGPSLRSVPSLVGSVSSAFSSGLVSGTSSALRTITRV 360
           MGMAIATGFLDSGHSTVADLLHSSGPSLRSVPSLVGSVSSAFSSGLVSGTSSALRTITRV
Sbjct: 301 MGMAIATGFLDSGHSTVADLLHSSGPSLRSVPSLVGSVSSAFSSGLVSGTSSALRTITRV 360

Query: 361 LETVEQRTVEGIRSAMRYLTSHLTPRQAQADPNYD 395
           LETVEQRTVEGIRSAMRYLTSHLTPRQAQADPNYD
Sbjct: 361 LETVEQRTVEGIRSAMRYLTSHLTPRQAQADPNYD 395


>gi|226442791 runt-related transcription factor 2 isoform b [Homo
           sapiens]
          Length = 499

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 63/247 (25%), Positives = 95/247 (38%), Gaps = 30/247 (12%)

Query: 89  LPSQNPSP-LQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPES 147
           +P QNP P L  + S  NP    Q+ D R +QS   +         +SQM S        
Sbjct: 261 VPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTS-------- 312

Query: 148 APSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGP-----QAASTTKSAEEKAEHPKA 202
            PS  S    S+      P  +D     +GA+ + GP     Q  S +   E +  +P+ 
Sbjct: 313 -PSIHSTTPLSSTRGTGLPAITDVPRRISGAS-ELGPFSDPRQFPSISSLTESRFSNPRM 370

Query: 203 PHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGSVSPSPGPHEVALGRRPLDPS 262
            +P   A  +   PV  G ++  S       + PPP  GS     GP + +       P 
Sbjct: 371 HYP---ATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTS-----STPY 422

Query: 263 LYTASEENSYMRSMTSLLDRGEGSISSLADILVWSETTMGMAIATGFLDSGHSTV-ADLL 321
           LY  +   SY   M    DR    +     +   + T+ G  +    L + +  V AD  
Sbjct: 423 LYYGTSSGSYQFPMVPGGDRSPSRM-----LPPCTTTSNGSTLLNPNLPNQNDGVDADGS 477

Query: 322 HSSGPSL 328
           HSS P++
Sbjct: 478 HSSSPTV 484


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
            region 1 [Homo sapiens]
          Length = 1400

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 73/360 (20%), Positives = 132/360 (36%), Gaps = 46/360 (12%)

Query: 29   PLTADVLAVSSSVASTDWQDIDQASFKTATPRAISTSGDKDKSAVVPEHGQKTPRKITPL 88
            P+TA +LA+ S++A T   +   +S  T+ P   STSG K+ +A      + T   IT  
Sbjct: 1039 PVTASILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMSETTIAAITAS 1098

Query: 89   LPSQNPSPLQVSMSLQNP-AWDRQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPES 147
              +   +   V  +   P    +   D  T+      P +    + +S + S P   P +
Sbjct: 1099 EDTTVSTQTSVIAAESVPHTATKTPTDTTTASVSATVPKN----NTLSVITSTPSTAPNT 1154

Query: 148  APSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEA 207
            A    +   ++T       + +     T+          ASTT SA   A   KA     
Sbjct: 1155 ASKTMTTASKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSA-TTAISTKASGTTV 1213

Query: 208  EALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGSVSPSPGPHEVALGRRPLDPSLYTAS 267
            E+ PS   P            +  T   P   + + S + G H V+     +  +++  +
Sbjct: 1214 ESAPSTAPPTP---------AETTTASVPTTTSTTGSENTGHHTVS----SVPTTVFATA 1260

Query: 268  EENSYMRSMTSLLDRGEGSISSLADILVWSETTMGMAIATGFLDSGHSTVADLLHSSGPS 327
             E+S     T    R   S + +        T M  A+ TG               S  +
Sbjct: 1261 SESSTGSETT----RASTSATEVT-------TAMTTAMTTG---------------SETA 1294

Query: 328  LRSVPSLVGSVSSAFSSGLVSGTSSALRTI-TRVLETVEQRTVEGIRSAMRYLTSHLTPR 386
            + S  + V +  S FS+  V    +   ++ T    T+ Q T++ +  ++  + S +  +
Sbjct: 1295 VVSTKAPVTTTQSGFSTATVMPAKTTTASVSTTASTTLYQNTIDSVAKSVPTMDSTIASK 1354



 Score = 35.4 bits (80), Expect = 0.090
 Identities = 32/158 (20%), Positives = 57/158 (36%), Gaps = 15/158 (9%)

Query: 71  SAVVPEHGQKTP-----RKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFP 125
           SA   EHG++TP        +P  P++N        +  +PA   + ++   ++   + P
Sbjct: 479 SAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSP 538

Query: 126 SHLLGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAG-----ANG 180
                 +      +    +   +P+ P+   Q T     +   S A+    G     AN 
Sbjct: 539 V-----EPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANE 593

Query: 181 QHGPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVA 218
              P  A  T++ E  A     P P       D +P+A
Sbjct: 594 NTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLA 631



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 34/172 (19%), Positives = 66/172 (38%), Gaps = 24/172 (13%)

Query: 71  SAVVPEHGQKTP-----RKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFP 125
           SA   EH ++TP        +P  P++N        +  +PA   + ++   ++   +FP
Sbjct: 660 SAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFP 719

Query: 126 SH------LLGKDKMSQMASVP----EREPESAPSAPSAELQSTQHMEAQPVESDADHVT 175
           +           +K +   + P    +R P +     S+  + T+H E  P+ ++   ++
Sbjct: 720 AEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLS 779

Query: 176 AG---------ANGQHGPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVA 218
                      AN +  P  A  T++ E  A     P P       D +P+A
Sbjct: 780 PAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLA 831


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 37/113 (32%), Positives = 51/113 (45%), Gaps = 9/113 (7%)

Query: 141 PEREPESAPSAPS-AELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEH 199
           P   P +AP+ P  A  Q+     A P  + A    AG +GQ GP AA+   +   KAE 
Sbjct: 287 PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAES 346

Query: 200 PK----APHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGSVSPSPG 248
           PK    A  P A+ L +   P +  A++V  +G        P PA    P+PG
Sbjct: 347 PKRVVQAAPPAAQTLAA-SGPASTAASMV--IGPTMQGAL-PSPAAVPPPAPG 395


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 54/194 (27%), Positives = 70/194 (36%), Gaps = 28/194 (14%)

Query: 89  LPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPESA 148
           +P   P  LQ   SLQ      QVQ ++ SQS    PS    KD         +++P   
Sbjct: 265 MPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSE--PSQPQQKDPQQ---PAQQQQPAQQ 319

Query: 149 PSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEAE 208
           P  PS +  S + ++   V S  +            +AA        K E    P P A 
Sbjct: 320 PKKPSPQPSSPRQVKRAVVVSPKEE----------NKAAEPPPPKIPKIETTHPPLPPAH 369

Query: 209 ALPSDESPVAMGANVVDSLG-----DLQTWFFPPP--PAGSVSPSPGPHEVALGRRPLDP 261
             P  + P+A      +  G     DL     PPP  PA    P P PH       P  P
Sbjct: 370 PPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPP----PPPP 425

Query: 262 SLYTA--SEENSYM 273
           S Y    S  +SYM
Sbjct: 426 SSYMTGMSTTSSYM 439


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 52/216 (24%), Positives = 77/216 (35%), Gaps = 32/216 (14%)

Query: 68  KDKSAVVPEHGQKTPRKITPLL------PSQNPSPLQVSMSLQNPAWD-RQVQDARTSQS 120
           K +    P  G   PRK  P +      P + P+PL  S S   P+ D RQV++  T + 
Sbjct: 351 KPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEV 410

Query: 121 LVVFPSHLLGKDKMSQMASVPEREPESAPSAPS-AELQSTQHMEAQP--------VESDA 171
               P+  L     +      E + E AP+APS A   +  H E+ P        +   +
Sbjct: 411 AQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTS 470

Query: 172 DHVTAGANGQHGPQAASTTKSAE--EKAEHPKA---PHPEAEALPSDESPVAMGANVVDS 226
              T        P A+     A     +E P A   P    E+L S+ +    GA +++ 
Sbjct: 471 SPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLE- 529

Query: 227 LGDLQTWFFPPPPAGSVSPSPGPHEVALGRRPLDPS 262
                     PP     S  P  H       P+  S
Sbjct: 530 ----------PPAVPKSSSEPAVHAPGTPGNPVSLS 555


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 58/277 (20%), Positives = 105/277 (37%), Gaps = 36/277 (12%)

Query: 16   SKDSPAGEPQGQVPLTADVLAVSSSVASTDWQDIDQASFKTATPRAISTSGDKDKSAVVP 75
            S  S +    G++  +    + SS ++S+ +    Q S  ++  +  S SG K  S+ + 
Sbjct: 1102 SSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS--QGSSGSSQSKNSSQSGGKPGSSPIT 1159

Query: 76   EHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLL---GKD 132
            +HG  +    T + P   PS      SL NP+  +            + PSH     G D
Sbjct: 1160 KHGLSSGSSSTKMKPQGKPS------SLMNPSLSKP----------NISPSHSRPPGGSD 1203

Query: 133  KM-SQMASVPEREPESAPSAPSAELQSTQHM----EAQPVESDADHVTAGANGQHGPQAA 187
            K+ S M  VP   P S   +P +      HM     +  ++S +   ++G+  Q  P ++
Sbjct: 1204 KLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSS 1263

Query: 188  STTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGSVSPSP 247
            ++  ++        +    ++         +   N   SL    T        G V+  P
Sbjct: 1264 NSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSL----TAVIDKLKHGVVTSGP 1319

Query: 248  GPHEVALGRRPLDPSLYTASEENSYMRSMTSLLDRGE 284
            G      G  PLD  +  ++  +S+  S    +  GE
Sbjct: 1320 G------GEDPLDGQMGVSTNSSSHPMSSKHNMSGGE 1350


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 58/251 (23%), Positives = 92/251 (36%), Gaps = 43/251 (17%)

Query: 8   LGNVDDSRSKDSPA-GEPQGQVPLTADVLAVS------SSVASTDWQDIDQA-------- 52
           LGN+  ++   SPA G PQ   P+   V A        SS  S+D  D ++A        
Sbjct: 495 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ 554

Query: 53  ---SFKTATPRAISTSGDKDKSAVVP--EHGQKTPRKITPLLPSQNPSPLQVSMSLQNPA 107
              + K    +A     +   SA V     G + PRK          SP  V+   Q PA
Sbjct: 555 AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA-VAGGTQRPA 613

Query: 108 WDRQV------QDARTSQSLVVFPSHLLGKDKMSQMASVPER-----------EPESAPS 150
            D         ++ +T  ++ V  +  +GK    + ASVP +             ++ P+
Sbjct: 614 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPT 673

Query: 151 APSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEAEAL 210
               + +  +  E+   ESD++   A        Q  ++ K  + KA    A  P A+  
Sbjct: 674 VTQVKAEKQEDSESSEEESDSEEAAASP-----AQVKTSVKKTQAKANPAAARAPSAKGT 728

Query: 211 PSDESPVAMGA 221
            S    V   A
Sbjct: 729 ISAPGKVVTAA 739


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 58/251 (23%), Positives = 92/251 (36%), Gaps = 43/251 (17%)

Query: 8   LGNVDDSRSKDSPA-GEPQGQVPLTADVLAVS------SSVASTDWQDIDQA-------- 52
           LGN+  ++   SPA G PQ   P+   V A        SS  S+D  D ++A        
Sbjct: 572 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ 631

Query: 53  ---SFKTATPRAISTSGDKDKSAVVP--EHGQKTPRKITPLLPSQNPSPLQVSMSLQNPA 107
              + K    +A     +   SA V     G + PRK          SP  V+   Q PA
Sbjct: 632 AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA-VAGGTQRPA 690

Query: 108 WDRQV------QDARTSQSLVVFPSHLLGKDKMSQMASVPER-----------EPESAPS 150
            D         ++ +T  ++ V  +  +GK    + ASVP +             ++ P+
Sbjct: 691 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPT 750

Query: 151 APSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEAEAL 210
               + +  +  E+   ESD++   A        Q  ++ K  + KA    A  P A+  
Sbjct: 751 VTQVKAEKQEDSESSEEESDSEEAAASP-----AQVKTSVKKTQAKANPAAARAPSAKGT 805

Query: 211 PSDESPVAMGA 221
            S    V   A
Sbjct: 806 ISAPGKVVTAA 816


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 58/251 (23%), Positives = 92/251 (36%), Gaps = 43/251 (17%)

Query: 8   LGNVDDSRSKDSPA-GEPQGQVPLTADVLAVS------SSVASTDWQDIDQA-------- 52
           LGN+  ++   SPA G PQ   P+   V A        SS  S+D  D ++A        
Sbjct: 572 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ 631

Query: 53  ---SFKTATPRAISTSGDKDKSAVVP--EHGQKTPRKITPLLPSQNPSPLQVSMSLQNPA 107
              + K    +A     +   SA V     G + PRK          SP  V+   Q PA
Sbjct: 632 AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA-VAGGTQRPA 690

Query: 108 WDRQV------QDARTSQSLVVFPSHLLGKDKMSQMASVPER-----------EPESAPS 150
            D         ++ +T  ++ V  +  +GK    + ASVP +             ++ P+
Sbjct: 691 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPT 750

Query: 151 APSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEAEAL 210
               + +  +  E+   ESD++   A        Q  ++ K  + KA    A  P A+  
Sbjct: 751 VTQVKAEKQEDSESSEEESDSEEAAASP-----AQVKTSVKKTQAKANPAAARAPSAKGT 805

Query: 211 PSDESPVAMGA 221
            S    V   A
Sbjct: 806 ISAPGKVVTAA 816


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 58/251 (23%), Positives = 92/251 (36%), Gaps = 43/251 (17%)

Query: 8   LGNVDDSRSKDSPA-GEPQGQVPLTADVLAVS------SSVASTDWQDIDQA-------- 52
           LGN+  ++   SPA G PQ   P+   V A        SS  S+D  D ++A        
Sbjct: 495 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ 554

Query: 53  ---SFKTATPRAISTSGDKDKSAVVP--EHGQKTPRKITPLLPSQNPSPLQVSMSLQNPA 107
              + K    +A     +   SA V     G + PRK          SP  V+   Q PA
Sbjct: 555 AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA-VAGGTQRPA 613

Query: 108 WDRQV------QDARTSQSLVVFPSHLLGKDKMSQMASVPER-----------EPESAPS 150
            D         ++ +T  ++ V  +  +GK    + ASVP +             ++ P+
Sbjct: 614 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPT 673

Query: 151 APSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEAEAL 210
               + +  +  E+   ESD++   A        Q  ++ K  + KA    A  P A+  
Sbjct: 674 VTQVKAEKQEDSESSEEESDSEEAAASP-----AQVKTSVKKTQAKANPAAARAPSAKGT 728

Query: 211 PSDESPVAMGA 221
            S    V   A
Sbjct: 729 ISAPGKVVTAA 739


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 58/251 (23%), Positives = 92/251 (36%), Gaps = 43/251 (17%)

Query: 8   LGNVDDSRSKDSPA-GEPQGQVPLTADVLAVS------SSVASTDWQDIDQA-------- 52
           LGN+  ++   SPA G PQ   P+   V A        SS  S+D  D ++A        
Sbjct: 572 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ 631

Query: 53  ---SFKTATPRAISTSGDKDKSAVVP--EHGQKTPRKITPLLPSQNPSPLQVSMSLQNPA 107
              + K    +A     +   SA V     G + PRK          SP  V+   Q PA
Sbjct: 632 AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA-VAGGTQRPA 690

Query: 108 WDRQV------QDARTSQSLVVFPSHLLGKDKMSQMASVPER-----------EPESAPS 150
            D         ++ +T  ++ V  +  +GK    + ASVP +             ++ P+
Sbjct: 691 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPT 750

Query: 151 APSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEAEAL 210
               + +  +  E+   ESD++   A        Q  ++ K  + KA    A  P A+  
Sbjct: 751 VTQVKAEKQEDSESSEEESDSEEAAASP-----AQVKTSVKKTQAKANPAAARAPSAKGT 805

Query: 211 PSDESPVAMGA 221
            S    V   A
Sbjct: 806 ISAPGKVVTAA 816


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 58/251 (23%), Positives = 92/251 (36%), Gaps = 43/251 (17%)

Query: 8   LGNVDDSRSKDSPA-GEPQGQVPLTADVLAVS------SSVASTDWQDIDQA-------- 52
           LGN+  ++   SPA G PQ   P+   V A        SS  S+D  D ++A        
Sbjct: 572 LGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQ 631

Query: 53  ---SFKTATPRAISTSGDKDKSAVVP--EHGQKTPRKITPLLPSQNPSPLQVSMSLQNPA 107
              + K    +A     +   SA V     G + PRK          SP  V+   Q PA
Sbjct: 632 AKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPA-VAGGTQRPA 690

Query: 108 WDRQV------QDARTSQSLVVFPSHLLGKDKMSQMASVPER-----------EPESAPS 150
            D         ++ +T  ++ V  +  +GK    + ASVP +             ++ P+
Sbjct: 691 EDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPT 750

Query: 151 APSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEAEAL 210
               + +  +  E+   ESD++   A        Q  ++ K  + KA    A  P A+  
Sbjct: 751 VTQVKAEKQEDSESSEEESDSEEAAASP-----AQVKTSVKKTQAKANPAAARAPSAKGT 805

Query: 211 PSDESPVAMGA 221
            S    V   A
Sbjct: 806 ISAPGKVVTAA 816


>gi|38570099 glutamine-rich 1 [Homo sapiens]
          Length = 776

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 59/244 (24%), Positives = 94/244 (38%), Gaps = 40/244 (16%)

Query: 11  VDDSRSKDSPAGEPQGQVPLTADVLAVSSSVASTDWQDIDQASFKTATPRAISTSGDKDK 70
           +D   SK   A +   Q   T  V     +   TD  ++  +  + A P  ++TS     
Sbjct: 31  LDSLASKGPEALQEFQQTATTTMVYQQGGNCIYTDSTEVAGSLLELACP--VTTS----- 83

Query: 71  SAVVPEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLLG 130
             V P+  Q+   ++      Q P  +QV + +Q      Q   A+ S  L V   H   
Sbjct: 84  --VQPQTQQEQQIQV------QQPQQVQVQVQVQQSP---QQVSAQLSPQLTV---HQPT 129

Query: 131 KDKMSQMASVPEREPESA-PSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAAST 189
           +  +     +  + P+SA PS  +  LQS    + Q  +    HV          QAA  
Sbjct: 130 EQPIQVQVQIQGQAPQSAAPSIQTPSLQSPSPSQLQAAQIQVQHV----------QAAQQ 179

Query: 190 TKSAEEKAEHPKAPHPEAEALPSDESPVAMGANV-VDSLGDLQTWFFPPPPAGSVSPSPG 248
            ++AE   EH   PH + +A       +A G  + + ++G L      PPP+   SP  G
Sbjct: 180 IQAAEIPEEH--IPHQQIQAQLVAGQSLAGGQQIQIQTVGALS-----PPPSQQGSPREG 232

Query: 249 PHEV 252
              V
Sbjct: 233 ERRV 236


>gi|38570097 glutamine-rich 1 [Homo sapiens]
          Length = 776

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 59/244 (24%), Positives = 94/244 (38%), Gaps = 40/244 (16%)

Query: 11  VDDSRSKDSPAGEPQGQVPLTADVLAVSSSVASTDWQDIDQASFKTATPRAISTSGDKDK 70
           +D   SK   A +   Q   T  V     +   TD  ++  +  + A P  ++TS     
Sbjct: 31  LDSLASKGPEALQEFQQTATTTMVYQQGGNCIYTDSTEVAGSLLELACP--VTTS----- 83

Query: 71  SAVVPEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLLG 130
             V P+  Q+   ++      Q P  +QV + +Q      Q   A+ S  L V   H   
Sbjct: 84  --VQPQTQQEQQIQV------QQPQQVQVQVQVQQSP---QQVSAQLSPQLTV---HQPT 129

Query: 131 KDKMSQMASVPEREPESA-PSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAAST 189
           +  +     +  + P+SA PS  +  LQS    + Q  +    HV          QAA  
Sbjct: 130 EQPIQVQVQIQGQAPQSAAPSIQTPSLQSPSPSQLQAAQIQVQHV----------QAAQQ 179

Query: 190 TKSAEEKAEHPKAPHPEAEALPSDESPVAMGANV-VDSLGDLQTWFFPPPPAGSVSPSPG 248
            ++AE   EH   PH + +A       +A G  + + ++G L      PPP+   SP  G
Sbjct: 180 IQAAEIPEEH--IPHQQIQAQLVAGQSLAGGQQIQIQTVGALS-----PPPSQQGSPREG 232

Query: 249 PHEV 252
              V
Sbjct: 233 ERRV 236


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 84/390 (21%), Positives = 141/390 (36%), Gaps = 25/390 (6%)

Query: 14   SRSKDSPAGEPQGQVPLTADVLAVSSSVASTDWQDIDQASFKTATPRAISTSG---DKDK 70
            SRS  SP  + + ++ L   +   S            ++   ++ P+A S +     +  
Sbjct: 759  SRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSS 818

Query: 71   SAVVPEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDAR-TSQSLVVFPS--- 126
            S+  P+   KTP + +    S +P     +   Q      Q  +   T Q    F S   
Sbjct: 819  SSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878

Query: 127  -HLLGK--DKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANGQHG 183
              L  +   + S   S P R   S P   S    S+   + + + S      +G++    
Sbjct: 879  PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP 938

Query: 184  PQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGSV 243
             +  S T     ++  P   + E+  LP        G++  D+    +T     PP  S 
Sbjct: 939  SRVTSRTTPRRSRSVSP-CSNVESRLLPRYSHS---GSSSPDTKVKPET-----PPRQSH 989

Query: 244  SPSPGPHEVALGRRPLDPSLYTASEENSYMRSMTSLLDRGEGSISSLADILVWSETTMG- 302
            S S  P+     + P  PSL  +       +S  SL+    GS+S  A   V S T  G 
Sbjct: 990  SGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAG--VKSSTPPGE 1047

Query: 303  --MAIATGFLDSGHSTVAD-LLHSSGPSLRSVPSLVGSVSSAFSSGLVSGTSSALRTITR 359
                +++  L     T  D    +S P +R   S   S+ S   +    G S +   +T 
Sbjct: 1048 SYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTE 1107

Query: 360  VLETVEQRTVEGIRSAMRYLTSHLTPRQAQ 389
            +      R   G  SA   L S ++P Q++
Sbjct: 1108 LASRSPIRQDRGEFSASPMLKSGMSPEQSR 1137



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 52/249 (20%), Positives = 91/249 (36%), Gaps = 39/249 (15%)

Query: 4    PGYPLGNVDDSRSKDSPAGEPQGQVPLT-ADVLAVSSSVASTDWQDIDQASFKTATPRAI 62
            PG P  +V +  +    A +P     L  A     SSS +S+       +S  +++  + 
Sbjct: 2499 PGVPHSDVGEPPASTG-AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSG 2557

Query: 63   STSGDKDKSAVVPEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLV 122
            S+S D + S++  +     P      +PS  P+P +             V++ R  +   
Sbjct: 2558 SSSSDSEGSSLPVQ-----PEVALKRVPSPTPAPKEA------------VREGRPPE--- 2597

Query: 123  VFPSHLLGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANGQH 182
              P+    K + S  +S       S+ S+ S+   S+         S +   ++ ++   
Sbjct: 2598 --PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS--------SSSSSSSSSSSSSS 2647

Query: 183  GPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGS 242
             P  A     A  K   PK P P      S   P       +DSL D ++  + P     
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKP-------IDSLRDSRSLSYSPVERRR 2700

Query: 243  VSPSPGPHE 251
             SP P P +
Sbjct: 2701 PSPQPSPRD 2709



 Score = 33.5 bits (75), Expect = 0.34
 Identities = 44/242 (18%), Positives = 84/242 (34%), Gaps = 35/242 (14%)

Query: 34   VLAVSSSVASTDWQDIDQASFKTATPRAISTSGDKDKSAVVPEHGQKTPRKITPLLPSQN 93
            ++A ++ VA +  Q +   +  T T    S++GD +    VP  G   P       P+  
Sbjct: 2462 LIAQTTPVAGS--QSLSSGAVATTT----SSAGDHNGMLSVPAPG--VPHSDVGEPPAST 2513

Query: 94   PSPLQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPESAPSAPS 153
             +    +++   PA +R+   + +S S     S        S  +S  + E  S P  P 
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573

Query: 154  AELQSTQHMEAQPVESDAD---------------HVTAGANGQHGPQAASTTKSAEEKAE 198
              L+        P E+  +                 ++ ++      ++S++ S+   + 
Sbjct: 2574 VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633

Query: 199  HPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGSVSPSPGPHEVALGRRP 258
               +    + +  S  SP   G   +            P PA    P PG       R+P
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQAL------------PKPASPKKPPPGERRSRSPRKP 2681

Query: 259  LD 260
            +D
Sbjct: 2682 ID 2683



 Score = 32.0 bits (71), Expect = 1.00
 Identities = 58/249 (23%), Positives = 91/249 (36%), Gaps = 32/249 (12%)

Query: 49   IDQASFKTATPRAISTSGDKDKSAVVPEH--GQKTPRKITPLLPSQNPSPLQVSMSLQNP 106
            +D+A  +T  P A S S    + A  P    GQ   + + P    Q  SP+  + S Q+ 
Sbjct: 2402 LDRARSRTP-PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSR 2460

Query: 107  AWDRQVQDARTSQSLV--VFPSHLLGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEA 164
                Q      SQSL      +        + M SVP      AP  P +++        
Sbjct: 2461 CLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP------APGVPHSDVGEP----- 2509

Query: 165  QPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVV 224
             P  + A   +A A  Q   +  S++ S+   +         + +  S  S  + G++  
Sbjct: 2510 -PASTGAQQPSALAALQPAKERRSSSSSSSSSSS-------SSSSSSSSSSSSSSGSSSS 2561

Query: 225  DSLGDLQTWFFPPPPAGSV----SPSPGPHEVALGRRPLDPSLYTASEENSYMRSMTSLL 280
            DS G       P  P  ++    SP+P P E     RP +P+       +S   S +S  
Sbjct: 2562 DSEGSS----LPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS 2617

Query: 281  DRGEGSISS 289
                 S SS
Sbjct: 2618 SSSSSSSSS 2626


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 45/190 (23%), Positives = 69/190 (36%), Gaps = 29/190 (15%)

Query: 75  PEHGQKTP----RKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLLG 130
           PE    +P     +++P       SPL  ++ L  P  +  +        L   P     
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPE---- 508

Query: 131 KDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPV-----ESDADHVTAGANGQHGPQ 185
               S +   P   PE +P +P+ E   +   EA P+     ES              P+
Sbjct: 509 SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPE 568

Query: 186 AASTTKSAEEK------AEHPKAPHPEAEAL--PSDESPVAMGANVVDSLGDLQTWFFPP 237
           A+  +   EE        E P +P PEA  L  P +ESP++            ++   PP
Sbjct: 569 ASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE--------ESPLSPP 620

Query: 238 PPAGSVSPSP 247
           P A  +SP P
Sbjct: 621 PEASRLSPPP 630



 Score = 37.0 bits (84), Expect = 0.031
 Identities = 60/275 (21%), Positives = 96/275 (34%), Gaps = 45/275 (16%)

Query: 17  KDSPAGEPQGQVPLTADVLAVSSSVASTDWQDIDQASFKTATPRAISTSGDKDKSAVVPE 76
           ++SP   P+   P  A    +S    ++      + S  +  P  + TS   + S + P 
Sbjct: 516 EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSP- 574

Query: 77  HGQKTPRKITPLLPSQNPSPLQVSMSLQN--PAWDRQVQDARTSQSLVVFP---SHLLGK 131
                P + +P+ P    SP+          P ++         +S +  P   S L   
Sbjct: 575 -----PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP 629

Query: 132 DKMSQMASVPEREPESAPSAPS--AELQSTQHMEAQPVESDADHVTAGANGQHGPQAAST 189
            + S M+  PE  P S P   S  + L     +   P ES        +     P+A+  
Sbjct: 630 PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRL 689

Query: 190 TKSAEEKA------EHPKAPHPEAE--ALPSDESPVAMGANVVDSLGDLQTWFFPPPPAG 241
           +   E+        + P +P PE    +LP +ESP+                  P P   
Sbjct: 690 SPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL-----------------LPLPEEP 732

Query: 242 SVSP-------SPGPHEVALGRRPLDPSLYTASEE 269
            + P       SP P E  L  RP +P L   +EE
Sbjct: 733 QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEE 767



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 47/191 (24%), Positives = 68/191 (35%), Gaps = 37/191 (19%)

Query: 75  PEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQ-------DARTSQSLVVFP-- 125
           PE    +P+   P L S  P    +S  L+ P    + +            + L +FP  
Sbjct: 828 PEESHLSPQSEEPCL-SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPP 886

Query: 126 -----SHLLGKDKMSQMASVPERE-PESAPSAPSAELQ-STQHMEAQPVESDADHVTAGA 178
                S LLG+  +S+    P    PE  P +PS E   S Q M   P+      +   A
Sbjct: 887 GEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAA 946

Query: 179 NGQHGPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPP 238
                   A    S   + E+P     +++     ESP+A           L+T   PPP
Sbjct: 947 --------APPALSPLGELEYPFGAKGDSDP----ESPLAAPI--------LETPISPPP 986

Query: 239 PAGSVSPSPGP 249
            A    P P P
Sbjct: 987 EANCTDPEPVP 997



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 53/245 (21%), Positives = 81/245 (33%), Gaps = 42/245 (17%)

Query: 8    LGNVDDSRSKDSPAGEPQGQVPL-------------TADVLAVSSSVASTDWQDIDQASF 54
            +G ++ SR+  SP  + Q QV L             +   L  +  +   +   +D A  
Sbjct: 3975 MGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVS 4034

Query: 55   KTATPRAISTSGDKDKSAVVPEHGQKTPRKITP--------LLPSQNPSPLQVSMSLQNP 106
              AT    +  G        PE     P ++ P        LL    P P   S+ LQ P
Sbjct: 4035 SEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPP 4094

Query: 107  AWDRQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQP 166
               R     +   SL+    H  G     Q+ S             S+E  S  H+ AQP
Sbjct: 4095 L--RLPGQQQQQVSLL----HTAGGGSHGQLGS-----------GSSSEASSVPHLLAQP 4137

Query: 167  VESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDS 226
              S  D   +      GPQ     +  +     P+ P P          P   G  ++ +
Sbjct: 4138 SVSLGDQPGSMTQNLLGPQQPMLERPMQNNT-GPQPPKPGPVLQSGQGLP---GVGIMPT 4193

Query: 227  LGDLQ 231
            +G L+
Sbjct: 4194 VGQLR 4198


>gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2
           [Homo sapiens]
          Length = 659

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 44/189 (23%), Positives = 74/189 (39%), Gaps = 18/189 (9%)

Query: 73  VVPEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFPS----HL 128
           V  ++G   P  + P L      P  +  +   P WD Q+ D+  S+SL         + 
Sbjct: 347 VARKNGYPLPEGLPPTL-----QPEYLQAAFPKPKWDCQLFDSY-SESLPANQQPRDLNR 400

Query: 129 LGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAG------ANGQH 182
           + K  +  MA +P    +   S     L+ST + EA P +   D  T        A  + 
Sbjct: 401 MEKTSVKDMADLPVPN-QDVTSDDKQALKSTIN-EALPKDVSEDPATPKDSNSLKARPRS 458

Query: 183 GPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGS 242
              ++++ + A ++ E P  P P  +   S  S + +      S+   ++   PPPPA  
Sbjct: 459 RSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALP 518

Query: 243 VSPSPGPHE 251
             P P   E
Sbjct: 519 PRPCPSQSE 527


>gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1
           [Homo sapiens]
          Length = 660

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 44/189 (23%), Positives = 74/189 (39%), Gaps = 18/189 (9%)

Query: 73  VVPEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFPS----HL 128
           V  ++G   P  + P L      P  +  +   P WD Q+ D+  S+SL         + 
Sbjct: 348 VARKNGYPLPEGLPPTL-----QPEYLQAAFPKPKWDCQLFDSY-SESLPANQQPRDLNR 401

Query: 129 LGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAG------ANGQH 182
           + K  +  MA +P    +   S     L+ST + EA P +   D  T        A  + 
Sbjct: 402 MEKTSVKDMADLPVPN-QDVTSDDKQALKSTIN-EALPKDVSEDPATPKDSNSLKARPRS 459

Query: 183 GPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGS 242
              ++++ + A ++ E P  P P  +   S  S + +      S+   ++   PPPPA  
Sbjct: 460 RSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPATKSGLLPPPPALP 519

Query: 243 VSPSPGPHE 251
             P P   E
Sbjct: 520 PRPCPSQSE 528


>gi|46243671 G protein-coupled receptor 152 [Homo sapiens]
          Length = 470

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 47/184 (25%), Positives = 65/184 (35%), Gaps = 40/184 (21%)

Query: 78  GQKTPRKITPLLPSQNPS---PLQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLLGKDKM 134
           G  TP +    L S+ P+   P+  + S  +P    QV      +S           D  
Sbjct: 323 GSFTPTEPQTQLDSEGPTLPEPMAEAQSQMDPVAQPQVNPTLQPRS-----------DPT 371

Query: 135 SQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAE 194
           +Q    P  +P+S P+A     Q   ++ AQP         A  N Q    AAS+  S  
Sbjct: 372 AQPQLNPTAQPQSDPTA-----QPQLNLMAQPQSDSVAQPQADTNVQTPAPAASSVPSPC 426

Query: 195 EKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGSVSPSPGPHEVAL 254
           ++A    + HP   AL   E P                    PP +   SPS  P E A 
Sbjct: 427 DEASPTPSSHPTPGAL---EDPAT------------------PPASEGESPSSTPPEAAP 465

Query: 255 GRRP 258
           G  P
Sbjct: 466 GAGP 469


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
            homolog 2 [Homo sapiens]
          Length = 1210

 Score = 37.7 bits (86), Expect = 0.018
 Identities = 38/201 (18%), Positives = 74/201 (36%), Gaps = 18/201 (8%)

Query: 131  KDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVT----------AGANG 180
            K + S  +S  +   ++ PS PS++    + +   PV S +              A   G
Sbjct: 834  KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG 893

Query: 181  QHGPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPA 240
            Q  P++AS+TKS  + +  PK    E +   S         +  +         FP P  
Sbjct: 894  QDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANP--------FPVPSL 945

Query: 241  GSVSPSPGPHEVALGRRPLDPSLYTASEENSYMRSMTSLLDRGEGSISSLADILVWSETT 300
             + +  PG  +V   ++  D  +  A +       MT  + +    + ++   +     T
Sbjct: 946  PNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIAT 1005

Query: 301  MGMAIATGFLDSGHSTVADLL 321
               + ++    S +S   DL+
Sbjct: 1006 ESESQSSKSAYSVYSETVDLI 1026



 Score = 29.3 bits (64), Expect = 6.5
 Identities = 30/127 (23%), Positives = 51/127 (40%), Gaps = 10/127 (7%)

Query: 90  PSQNPSPLQVSMSLQNPAWDRQVQD--ARTSQSLVVFPSHLLGKDKM------SQMASVP 141
           PS+ P P + S  + +   +++  D  ++T  +     S +L  D        S     P
Sbjct: 382 PSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTP 441

Query: 142 EREPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPK 201
           E+ P S  SAP +  QS     A    S A+  +   +       + ++ S  E+ E  +
Sbjct: 442 EKPPSS--SAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLE 499

Query: 202 APHPEAE 208
            P PE E
Sbjct: 500 TPAPEPE 506


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 37.7 bits (86), Expect = 0.018
 Identities = 82/347 (23%), Positives = 127/347 (36%), Gaps = 41/347 (11%)

Query: 20  PAGEPQGQVPLTADVLAVSSSVASTDWQDIDQASFKTATPRAISTSGDKDKSAVVPEH-G 78
           P   P+G+   T   L +  S+   +W+D       + +P     S  + + ++ P +  
Sbjct: 517 PQSPPEGEN--THSPLQIVPSLP--EWED-------SLSPHYFPQSPPQGEDSLSPHYFP 565

Query: 79  QKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFP-SHLLGKDKMSQM 137
           Q  P+    L P   P   Q   SL    + +       S S + FP S L G++  S +
Sbjct: 566 QSPPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLYFPQSPLQGEEFQSSL 625

Query: 138 ------------ASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANGQ---H 182
                       +S+P+  PES+ S P   +QS  H    P E        G + Q    
Sbjct: 626 QSPVSICSSSTPSSLPQSFPESSQSPPEGPVQSPLHSPQSPPE--------GMHSQSPLQ 677

Query: 183 GPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGS 242
            P++A   + +    + P++P    ++L S   P +      DSL  L    FPP     
Sbjct: 678 SPESAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQS-PPEWEDSLSPLHFPQFPPQGEDF 736

Query: 243 VSPSPGPHEVALGRRPLD-PSLYTASEENSYMRSMTSLLDRGEGSISS--LADILVWSET 299
            S    P  +      L  P  +  S ++       S L R   S  S  LA +L  S  
Sbjct: 737 QSSLQSPVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHE 796

Query: 300 TMGMAIATGFLDSGHSTVADLLHSSGPSLRSVPSLVGSVSSAFSSGL 346
           +   +   G   S   +      SS  S  S  S V S  S+ SS L
Sbjct: 797 S-PQSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSPVSSFPSSTSSSL 842


>gi|226442783 runt-related transcription factor 2 isoform a [Homo
           sapiens]
          Length = 521

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 66/265 (24%), Positives = 98/265 (36%), Gaps = 44/265 (16%)

Query: 89  LPSQNPSP-LQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPES 147
           +P QNP P L  + S  NP    Q+ D R +QS   +         +SQM S     P  
Sbjct: 261 VPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTS-----PSI 315

Query: 148 APSAPSAELQSTQHMEAQPVE---SDADHVT---------------AGANGQHGP----- 184
             + P +  + T       V    SD D  T               AGA+ + GP     
Sbjct: 316 HSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQAGAS-ELGPFSDPR 374

Query: 185 QAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGSVS 244
           Q  S +   E +  +P+  +P   A  +   PV  G ++  S       + PPP  GS  
Sbjct: 375 QFPSISSLTESRFSNPRMHYP---ATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQ 431

Query: 245 PSPGPHEVALGRRPLDPSLYTASEENSYMRSMTSLLDRGEGSISSLADILVWSETTMGMA 304
              GP + +       P LY  +   SY   M    DR    +     +   + T+ G  
Sbjct: 432 SQSGPFQTS-----STPYLYYGTSSGSYQFPMVPGGDRSPSRM-----LPPCTTTSNGST 481

Query: 305 IATGFLDSGHSTV-ADLLHSSGPSL 328
           +    L + +  V AD  HSS P++
Sbjct: 482 LLNPNLPNQNDGVDADGSHSSSPTV 506


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
           [Homo sapiens]
          Length = 3969

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 41/138 (29%), Positives = 61/138 (44%), Gaps = 21/138 (15%)

Query: 39  SSVASTDWQDIDQASFKTATPRAISTSGDKDKSA---VVPEHGQKTPRKITPLLPSQNPS 95
           SS AS     +   S ++++P ++ TS D   S    V+PE    TP    PL  SQ+P 
Sbjct: 462 SSAASQHSSQMSSDSSRSSSP-SVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSP- 519

Query: 96  PLQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPESAPSAPSAE 155
                   +N + DR+ +  R S S   F S      K+S + S P+++  S+P  P   
Sbjct: 520 --------ENESNDRRSR--RYSVSERSFGSRTT--KKLSTLQSAPQQQTSSSPPPPLL- 566

Query: 156 LQSTQHMEAQPVESDADH 173
              T     QP  S +DH
Sbjct: 567 ---TPPPPLQPASSISDH 581



 Score = 32.3 bits (72), Expect = 0.76
 Identities = 31/133 (23%), Positives = 52/133 (39%), Gaps = 15/133 (11%)

Query: 78  GQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTS--QSLVVFPSHLLGKDKMS 135
           G+ +  +++PL P   PS +  S+S+        V    TS       FPSH L +   S
Sbjct: 760 GRLSSSELSPLTP---PSSVSSSLSIS-------VSPLATSALNPTFTFPSHSLTQ---S 806

Query: 136 QMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEE 195
             ++   + P    SAP+    S+      P  +       G N    P+  S  + A++
Sbjct: 807 GESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADK 866

Query: 196 KAEHPKAPHPEAE 208
             E  K+   + E
Sbjct: 867 SVEKDKSRERDRE 879


>gi|66934969 runt-related transcription factor 2 isoform c [Homo
           sapiens]
          Length = 507

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 66/265 (24%), Positives = 98/265 (36%), Gaps = 44/265 (16%)

Query: 89  LPSQNPSP-LQVSMSLQNPAWDRQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPES 147
           +P QNP P L  + S  NP    Q+ D R +QS   +         +SQM S     P  
Sbjct: 247 VPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTS-----PSI 301

Query: 148 APSAPSAELQSTQHMEAQPVE---SDADHVT---------------AGANGQHGP----- 184
             + P +  + T       V    SD D  T               AGA+ + GP     
Sbjct: 302 HSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQAGAS-ELGPFSDPR 360

Query: 185 QAASTTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANVVDSLGDLQTWFFPPPPAGSVS 244
           Q  S +   E +  +P+  +P   A  +   PV  G ++  S       + PPP  GS  
Sbjct: 361 QFPSISSLTESRFSNPRMHYP---ATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQ 417

Query: 245 PSPGPHEVALGRRPLDPSLYTASEENSYMRSMTSLLDRGEGSISSLADILVWSETTMGMA 304
              GP + +       P LY  +   SY   M    DR    +     +   + T+ G  
Sbjct: 418 SQSGPFQTS-----STPYLYYGTSSGSYQFPMVPGGDRSPSRM-----LPPCTTTSNGST 467

Query: 305 IATGFLDSGHSTV-ADLLHSSGPSL 328
           +    L + +  V AD  HSS P++
Sbjct: 468 LLNPNLPNQNDGVDADGSHSSSPTV 492


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
           sapiens]
          Length = 907

 Score = 37.0 bits (84), Expect = 0.031
 Identities = 34/146 (23%), Positives = 51/146 (34%), Gaps = 24/146 (16%)

Query: 128 LLGKDKMSQMASVPER-------EPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANG 180
           LLG+D ++ ++SVP          PE  P   +AE+ +     +      A        G
Sbjct: 382 LLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAVTAEVDLFG 441

Query: 181 QHGPQAASTTKSAEEKAEHPKAPHPEAEALP--SDESPVAMGANVVDSLGDLQTWFFPP- 237
                +     +A E A  P  P P A AL   S   P A      ++  +L  +   P 
Sbjct: 442 DAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPP 501

Query: 238 --------------PPAGSVSPSPGP 249
                         PP  + +PSP P
Sbjct: 502 ETSVPVVTPTASTAPPVPATAPSPAP 527


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 37.0 bits (84), Expect = 0.031
 Identities = 33/133 (24%), Positives = 57/133 (42%), Gaps = 19/133 (14%)

Query: 141  PEREPES---APSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKA 197
            P++EPE    + S PS E  +TQ  +   +E   +H+          + A  + SA  KA
Sbjct: 2144 PDKEPEKEDVSASGPSPE--ATQLAKQMELEQAVEHIA---------KLAEASASAAYKA 2192

Query: 198  EHPKAPHPEAEALPSDESP-----VAMGANVVDSLGDLQTWFFPPPPAGSVSPSPGPHEV 252
            + P+   PE    P+ ++       A+G+ + D  G+ + +  PPP  G       P   
Sbjct: 2193 DAPEGLAPEDRDKPAHQASETELAAAIGSIINDISGEPENFPAPPPYPGESQTDLQPPAG 2252

Query: 253  ALGRRPLDPSLYT 265
            A   +P +  + T
Sbjct: 2253 AQALQPSEEGMET 2265



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 46/184 (25%), Positives = 69/184 (37%), Gaps = 31/184 (16%)

Query: 55   KTATPRAISTSGDKDKSAVVPEHGQ-------KTPRKITPLLPSQNPSPLQVSMS-LQNP 106
            K   P+ +    D +     PE          KTP  + P  PS     L+ + S L+  
Sbjct: 1600 KDQKPKEVEKQEDTENHPKTPESAPENKDSELKTPPSVGP--PSVTVVTLESAPSALEKT 1657

Query: 107  AWDRQVQDARTSQSLVVFPSHLLGKDK-MSQMASVPEREPESAPSAPSAELQSTQHMEAQ 165
              D+ V+    ++   V P+ +  + K  S+ A  P  + E     P A+      M   
Sbjct: 1658 TGDKTVEAPLVTEEKTVEPATVSEEAKPASEPAPAPVEQLEQVDLPPGADPDKEAAMMPA 1717

Query: 166  PVES----------DADHVTAGANGQHG-----PQAAST---TKSAE--EKAEHPKAPHP 205
             VE           DA   T GA+         P+  ST   +K A+  E+A  PKA  P
Sbjct: 1718 GVEEGSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPLSKPAQKSEEANEPKAEKP 1777

Query: 206  EAEA 209
            +A A
Sbjct: 1778 DATA 1781



 Score = 29.3 bits (64), Expect = 6.5
 Identities = 46/235 (19%), Positives = 85/235 (36%), Gaps = 32/235 (13%)

Query: 14   SRSKDSPAG----EPQGQVPLTADVLAVSSSVASTDWQDIDQASFKTATP--RAISTSGD 67
            S+   +PAG         + LTA     S  ++S      D+ S +   P   ++ST   
Sbjct: 2868 SKGPQAPAGYANVATHSTLVLTAQTYNASPVISSVK---ADRPSLEKPEPIHLSVSTPVT 2924

Query: 68   KDKSAVVPEHGQKTPRKITPLLPSQNPSPLQVSMSLQNPAWDRQVQDARTSQSLVVFPSH 127
            +  +  V   G  TP  +        PS +  +  L +P            ++ V+ P++
Sbjct: 2925 QGGTVKVLTQGINTPPVLVHNQLVLTPSIVTTNKKLADPV-------TLKIETKVLQPAN 2977

Query: 128  LLGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAA 187
            L         +++    P + PS    E+       + P +    H+ A     H P+ +
Sbjct: 2978 L--------GSTLTPHHPPALPSKLPTEVNHVPSGPSIPADRTVSHLAAAKLDAHSPRPS 3029

Query: 188  STTKSAEEKAEHPKAPHPEAEALPSDESPVAMGANV-----VDSLGDLQTWFFPP 237
                S+  +A HP +    A    S  + V + A +     + S+   Q+   PP
Sbjct: 3030 GPGPSSFPRASHPSS---TASTALSTNATVMLAAGIPVPQFISSIHPEQSVIMPP 3081


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 37.0 bits (84), Expect = 0.031
 Identities = 72/285 (25%), Positives = 110/285 (38%), Gaps = 51/285 (17%)

Query: 33  DVLAVSSSVASTDWQDIDQASFKTATPRAISTSGDKDKSAVVPEHGQKTPRKITPLLPSQ 92
           D  A+SS  +S       Q S  +A+  A + + +   SA  P +      KI+ LLP  
Sbjct: 727 DFSALSSKNSSLSASPTSQQS--SASLAAATAATEAGPSATKPPNS-----KISGLLPQG 779

Query: 93  NPSPLQVSMSLQN-----PAWDRQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPES 147
            P  + ++++L N     P     +   R S SL V    LLG       AS       +
Sbjct: 780 LPGSIPLALALSNSGLPTPTPYFPILAGRGSTSLPVGTPSLLGAVSSGSAAS-------A 832

Query: 148 APSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEA 207
            P  P+  L ++   ++ PV        A A+    P +     SA +    P      A
Sbjct: 833 TPDTPT--LVASGAGDSAPV--------AAASVPAPPASIMERISASKGLISPMMARLAA 882

Query: 208 EAL-PSDESPVAMGANVVDSLGDLQTWFFPP----PPAGSVSPSPGPHEVALGRRPLDPS 262
            AL PS       G  V  +        FPP    P  G  + +PGPHE A   R LD +
Sbjct: 883 AALKPSATFDPGSGQQVTPAR-------FPPAQVKPEPGESTGAPGPHE-ASQDRSLDLT 934

Query: 263 LYTASEE---------NSYMRSMTSLLDRGEGSISSLADILVWSE 298
           +   S E         +S + S+ + + +G   + SL +I   +E
Sbjct: 935 VKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAE 979


>gi|119709822 castor homolog 1, zinc finger isoform b [Homo sapiens]
          Length = 1166

 Score = 37.0 bits (84), Expect = 0.031
 Identities = 72/285 (25%), Positives = 110/285 (38%), Gaps = 51/285 (17%)

Query: 33  DVLAVSSSVASTDWQDIDQASFKTATPRAISTSGDKDKSAVVPEHGQKTPRKITPLLPSQ 92
           D  A+SS  +S       Q S  +A+  A + + +   SA  P +      KI+ LLP  
Sbjct: 727 DFSALSSKNSSLSASPTSQQS--SASLAAATAATEAGPSATKPPNS-----KISGLLPQG 779

Query: 93  NPSPLQVSMSLQN-----PAWDRQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPES 147
            P  + ++++L N     P     +   R S SL V    LLG       AS       +
Sbjct: 780 LPGSIPLALALSNSGLPTPTPYFPILAGRGSTSLPVGTPSLLGAVSSGSAAS-------A 832

Query: 148 APSAPSAELQSTQHMEAQPVESDADHVTAGANGQHGPQAASTTKSAEEKAEHPKAPHPEA 207
            P  P+  L ++   ++ PV        A A+    P +     SA +    P      A
Sbjct: 833 TPDTPT--LVASGAGDSAPV--------AAASVPAPPASIMERISASKGLISPMMARLAA 882

Query: 208 EAL-PSDESPVAMGANVVDSLGDLQTWFFPP----PPAGSVSPSPGPHEVALGRRPLDPS 262
            AL PS       G  V  +        FPP    P  G  + +PGPHE A   R LD +
Sbjct: 883 AALKPSATFDPGSGQQVTPAR-------FPPAQVKPEPGESTGAPGPHE-ASQDRSLDLT 934

Query: 263 LYTASEE---------NSYMRSMTSLLDRGEGSISSLADILVWSE 298
           +   S E         +S + S+ + + +G   + SL +I   +E
Sbjct: 935 VKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAE 979


>gi|57634536 La ribonucleoprotein domain family, member 4B [Homo
           sapiens]
          Length = 738

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 18/129 (13%)

Query: 110 RQVQDARTSQSLVVFPSHLLGKDKMSQMASVPEREPESAPSAPSAELQSTQHMEAQPV-- 167
           ++VQ+ + S  L+  P         SQ +S+P       P+   +EL     +   PV  
Sbjct: 16  QRVQEGKDSAHLMNGPI----SQTTSQTSSIPPLS--QVPATKVSELNPNAEVWGAPVLH 69

Query: 168 ---ESDADHVTA------GANGQHGPQAASTTKSAEEKAEHPKAPHPEAEALPSDESPVA 218
               S AD V+A      G +   GPQ +      ++  E+   P P+ E+ P+D + +A
Sbjct: 70  LEASSAADGVSAAWEEVAGHHADRGPQGSDANGDGDQGHENAALPDPQ-ESDPADMNALA 128

Query: 219 MGANVVDSL 227
           +G +  DSL
Sbjct: 129 LGPSEYDSL 137


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.123    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,011,756
Number of Sequences: 37866
Number of extensions: 886111
Number of successful extensions: 4900
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 311
Number of HSP's that attempted gapping in prelim test: 4482
Number of HSP's gapped (non-prelim): 702
length of query: 395
length of database: 18,247,518
effective HSP length: 104
effective length of query: 291
effective length of database: 14,309,454
effective search space: 4164051114
effective search space used: 4164051114
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.