Guide to the Human Genome
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Search of human proteins with 227430410

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
         (359 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|227430410 POU class 5 homeobox 1B [Homo sapiens]                   753   0.0  
gi|42560248 POU domain, class 5, transcription factor 1 isoform ...   716   0.0  
gi|116235491 POU domain, class 5, transcription factor 1 isoform...   439   e-123
gi|23463326 POU domain class 5, transcription factor 2 [Homo sap...   256   2e-68
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s...   197   2e-50
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                      183   2e-46
gi|110624763 POU domain, class 3, transcription factor 4 [Homo s...   182   3e-46
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...   182   4e-46
gi|42476164 POU class 2 homeobox 1 [Homo sapiens]                     165   5e-41
gi|4505959 POU domain, class 2, transcription factor 2 [Homo sap...   165   5e-41
gi|148664218 POU transcription factor [Homo sapiens]                  162   4e-40
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...   134   2e-31
gi|170650730 pituitary specific transcription factor 1 isoform b...   132   6e-31
gi|4505955 pituitary specific transcription factor 1 isoform alp...   132   6e-31
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]     124   1e-28
gi|4505965 POU class 4 homeobox 3 [Homo sapiens]                      120   1e-27
gi|223890225 POU class 6 homeobox 1 [Homo sapiens]                    108   7e-24
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...    83   4e-16
gi|30410785 LIM homeobox protein 1 [Homo sapiens]                      48   1e-05
gi|11641283 LIM homeobox protein 5 [Homo sapiens]                      47   2e-05
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap...    47   3e-05
gi|24497589 aristaless related homeobox [Homo sapiens]                 46   5e-05
gi|15375314 LIM homeobox protein 4 [Homo sapiens]                      46   6e-05
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]            45   8e-05
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]             45   8e-05
gi|61969666 arginine-fifty homeobox [Homo sapiens]                     44   2e-04
gi|11386181 H2.0-like homeobox [Homo sapiens]                          43   4e-04
gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]           43   5e-04
gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]          43   5e-04
gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]          43   5e-04

>gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
          Length = 359

 Score =  753 bits (1944), Expect = 0.0
 Identities = 359/359 (100%), Positives = 359/359 (100%)

Query: 1   MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI 60
           MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI
Sbjct: 1   MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI 60

Query: 61  PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG 120
           PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG
Sbjct: 61  PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG 120

Query: 121 AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS 180
           AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS
Sbjct: 121 AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS 180

Query: 181 QKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENR 240
           QKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENR
Sbjct: 181 QKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENR 240

Query: 241 VRGNLENLFLQCPKPTLQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAA 300
           VRGNLENLFLQCPKPTLQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAA
Sbjct: 241 VRGNLENLFLQCPKPTLQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAA 300

Query: 301 GSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN 359
           GSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
Sbjct: 301 GSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN 359


>gi|42560248 POU domain, class 5, transcription factor 1 isoform 1
           [Homo sapiens]
          Length = 360

 Score =  716 bits (1849), Expect = 0.0
 Identities = 345/360 (95%), Positives = 348/360 (96%), Gaps = 1/360 (0%)

Query: 1   MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI 60
           MAGHLASDFAFSPPPGGGGDGP G EPGWVDP TWLSFQGPPGGPGIGPGVGPGSEVWGI
Sbjct: 1   MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGI 60

Query: 61  PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG 120
           PPCPPPYE CGGMAYCGPQVGVGLVPQGGLETSQPE EAGVGVESNS+GASPEPCTV PG
Sbjct: 61  PPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPG 120

Query: 121 AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS 180
           AVKLEKEKLEQNPE+SQDIKALQKELEQFAKLLKQKRITLGYTQADVGL LGVLFGKVFS
Sbjct: 121 AVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFS 180

Query: 181 QKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENR 240
           Q TICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETL+QARKRKRTSIENR
Sbjct: 181 QTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENR 240

Query: 241 VRGNLENLFLQCPKPTL-QISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA 299
           VRGNLENLFLQCPKPTL QISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA
Sbjct: 241 VRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA 300

Query: 300 AGSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN 359
           AGSPFSGGPVSFP APGPHFGTPGYGSPHFTALYSSVPFPEGE FPPVSV TLGSPMHSN
Sbjct: 301 AGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN 360


>gi|116235491 POU domain, class 5, transcription factor 1 isoform 2
           [Homo sapiens]
          Length = 265

 Score =  439 bits (1129), Expect = e-123
 Identities = 218/226 (96%), Positives = 220/226 (97%), Gaps = 1/226 (0%)

Query: 135 KSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSF 194
           +SQDIKALQKELEQFAKLLKQKRITLGYTQADVGL LGVLFGKVFSQ TICRFEALQLSF
Sbjct: 40  QSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSF 99

Query: 195 KNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPK 254
           KNMCKLRPLLQKWVEEADNNENLQEICKAETL+QARKRKRTSIENRVRGNLENLFLQCPK
Sbjct: 100 KNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPK 159

Query: 255 PTL-QISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPP 313
           PTL QISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFP 
Sbjct: 160 PTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPL 219

Query: 314 APGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN 359
           APGPHFGTPGYGSPHFTALYSSVPFPEGE FPPVSV TLGSPMHSN
Sbjct: 220 APGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN 265


>gi|23463326 POU domain class 5, transcription factor 2 [Homo
           sapiens]
          Length = 328

 Score =  256 bits (654), Expect = 2e-68
 Identities = 161/342 (47%), Positives = 196/342 (57%), Gaps = 38/342 (11%)

Query: 1   MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGG----PGIGPGVGPGSE 56
           MAGH  S+  F P PG GG GP G  P  VD LTWLS Q  PG     P + PG+ PG +
Sbjct: 1   MAGHRPSNH-FCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPD 59

Query: 57  VWGIPPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCT 116
           VW IP  P P+E  G +A C P++G               SEAG  +   S GA P P  
Sbjct: 60  VWRIPLGPLPHEFRGWIAPCRPRLGA--------------SEAGDWLRRPSEGALPGPYI 105

Query: 117 VPPGAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFG 176
                 KL            +DI  + KEL+Q AK L+QKR++LGY+QADVG+ +G LFG
Sbjct: 106 ALRSIPKLPPP---------EDISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFG 156

Query: 177 KVFSQKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAE-TLMQARKRKRT 235
           KV SQ TICRFEA QLS  NM KLRPLL+KW++E +  ENL  +CK E  L Q+ K +R 
Sbjct: 157 KVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVE-AENLLGLCKMEMILQQSGKWRRA 215

Query: 236 SIENRVRGNLENLFLQCPKPT-LQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQR 294
           S E R+  +LE  F +CPKPT  QISHIA  L L+KDVVRVWF NR + G R ++D + R
Sbjct: 216 SRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPR 275

Query: 295 EDFEAAGSPFSGGPVSFPPAPGPHFGTP-GYGSPHFTALYSS 335
           E    AG P  G PV F      H G       PH+T LYS+
Sbjct: 276 EIVGTAGPPCPGAPVCF------HLGLGLPVDIPHYTRLYSA 311


>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
           sapiens]
          Length = 451

 Score =  197 bits (500), Expect = 2e-50
 Identities = 136/323 (42%), Positives = 168/323 (52%), Gaps = 60/323 (18%)

Query: 9   FAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYE 68
           +A +  PGGGG G  G           L+  G   GPG+   +        + P PPP+ 
Sbjct: 159 YAQAAYPGGGGGGLAGM----------LAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHL 208

Query: 69  LCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPGAVKLEKEK 128
              G A+       G    GGL  +      G G   +S G                   
Sbjct: 209 GAHGHAH-------GHAHAGGLHAAAAHLHPGAGGGGSSVG------------------- 242

Query: 129 LEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFE 188
                E S +      +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQ TICRFE
Sbjct: 243 -----EHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFE 297

Query: 189 ALQLSFKNMCKLRPLLQKWVEEADNNE----NLQEICKAETLMQARKR-KRTSIENRVRG 243
           ALQLSFKNMCKL+PLL KW+EE D++     NL +I       Q RKR KRTSIE  V+G
Sbjct: 298 ALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIA-----AQGRKRKKRTSIEVGVKG 352

Query: 244 NLENLFLQCPKPTL-QISHIAQQLGLEKDVVRVWFCNRRQKGKR----SSSDYAQREDFE 298
            LE+ FL+CPKP+  +I+ +A  L LEK+VVRVWFCNRRQK KR    + + +   +D  
Sbjct: 353 ALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVY 412

Query: 299 AAGSPFSGG----PVSFPPAPGP 317
           A G    GG    P S PP P P
Sbjct: 413 APGELGPGGGGASPPSAPPPPPP 435


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score =  183 bits (465), Expect = 2e-46
 Identities = 100/190 (52%), Positives = 125/190 (65%), Gaps = 5/190 (2%)

Query: 132 NPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQ 191
           +P   +D      +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQ TICRFEALQ
Sbjct: 309 DPHSDEDTPT-SDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ 367

Query: 192 LSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQ 251
           LSFKNMCKL+PLL KW+EEAD++               +++KRTSIE  V+G LE+ FL+
Sbjct: 368 LSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLK 427

Query: 252 CPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVS 310
           CPKP+ Q I+++A  L LEK+VVRVWFCNRRQK KR +    Q++  +   S        
Sbjct: 428 CPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSAD 487

Query: 311 FPPAPGPHFG 320
            PP   PH G
Sbjct: 488 TPP---PHHG 494


>gi|110624763 POU domain, class 3, transcription factor 4 [Homo
           sapiens]
          Length = 361

 Score =  182 bits (463), Expect = 3e-46
 Identities = 113/234 (48%), Positives = 133/234 (56%), Gaps = 17/234 (7%)

Query: 58  WGIPPCPPPYELCGGM---AYCGPQVGV-GLVPQGGLETSQPESEAGVGVESNSNGASPE 113
           WG  P P P     G     Y  P   V G++  GGL T  P   A    +S        
Sbjct: 114 WGASPAPNPSITSSGQPLNVYSQPGFTVSGMLEHGGL-TPPP---AAASAQSLHPVLREP 169

Query: 114 PCTVPPGAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGV 173
           P     G+   +    E+ P           ELEQFAK  KQ+RI LG+TQADVGL LG 
Sbjct: 170 PDHGELGSHHCQDHSDEETPTSD--------ELEQFAKQFKQRRIKLGFTQADVGLALGT 221

Query: 174 LFGKVFSQKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRK 233
           L+G VFSQ TICRFE LQLSFKNMCKL+PLL KW+EEAD++               +++K
Sbjct: 222 LYGNVFSQTTICRFEGLQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKK 281

Query: 234 RTSIENRVRGNLENLFLQCPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGKR 286
           RTSIE  V+G LE  FL+CPKP  Q IS +A  L LEK+VVRVWFCNRRQK KR
Sbjct: 282 RTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKR 335


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
           sapiens]
          Length = 443

 Score =  182 bits (462), Expect = 4e-46
 Identities = 112/250 (44%), Positives = 137/250 (54%), Gaps = 13/250 (5%)

Query: 49  PGVGPGSEVWGIPPCPPPYELC-GGMAYCGPQ------VGVGLVPQG----GLETSQPES 97
           PG G           PP      GG+ Y  P       +G G  P G    GL  +  E 
Sbjct: 163 PGPGAWRSAAAAAHLPPSMGASNGGLLYSQPSFTVNGMLGAGGQPAGLHHHGLRDAHDEP 222

Query: 98  EAGVGVESNSNGASPEPCTVPPGAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKR 157
                     +    +P   PP            +P   +D      +LEQFAK  KQ+R
Sbjct: 223 HHADHHPHPHSHPHQQPPPPPPPQGPPGHPGAHHDPHSDEDTPT-SDDLEQFAKQFKQRR 281

Query: 158 ITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENL 217
           I LG+TQADVGL LG L+G VFSQ TICRFEALQLSFKNMCKL+PLL KW+EEAD++   
Sbjct: 282 IKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSSGS 341

Query: 218 QEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPKPTLQ-ISHIAQQLGLEKDVVRVW 276
                       +++KRTSIE  V+G LE+ FL+CPKP+ Q I+ +A  L LEK+VVRVW
Sbjct: 342 PTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVVRVW 401

Query: 277 FCNRRQKGKR 286
           FCNRRQK KR
Sbjct: 402 FCNRRQKEKR 411


>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
          Length = 743

 Score =  165 bits (418), Expect = 5e-41
 Identities = 107/251 (42%), Positives = 140/251 (55%), Gaps = 29/251 (11%)

Query: 78  PQVGVGLVPQGGLETSQPE-SEAGVGVESNSNGASPEPCTVPP--GAVKLEKEKLEQNPE 134
           PQ   GL+    L T  P+ S+A +     S   + +P T      A  ++     Q+  
Sbjct: 212 PQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQSTP 271

Query: 135 KSQDIKALQK-----ELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEA 189
           K  D  +L++     ELEQFAK  KQ+RI LG+TQ DVGL +G L+G  FSQ TI RFEA
Sbjct: 272 KRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEA 331

Query: 190 LQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETL-------MQARKRKRTSIENRVR 242
           L LSFKNMCKL+PLL+KW+ +A+N  +   +     L       +  R++KRTSIE  +R
Sbjct: 332 LNLSFKNMCKLKPLLEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIR 391

Query: 243 GNLENLFLQCPKPTL-QISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAG 301
             LE  FL+  KPT  +I+ IA QL +EK+V+RVWFCNRRQK KR               
Sbjct: 392 VALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKR-------------IN 438

Query: 302 SPFSGGPVSFP 312
            P SGG  S P
Sbjct: 439 PPSSGGTSSSP 449


>gi|4505959 POU domain, class 2, transcription factor 2 [Homo
           sapiens]
          Length = 463

 Score =  165 bits (418), Expect = 5e-41
 Identities = 116/279 (41%), Positives = 148/279 (53%), Gaps = 52/279 (18%)

Query: 87  QGGLETSQPESEAGVGVESNSNGASPEPCTVPPGAVKLEKEKLEQNPEKSQDIKALQKEL 146
           QG L TSQP   AG+  +       P  C  PP            +PE+  D++    EL
Sbjct: 152 QGALLTSQPR--AGLPTQ-------PPKCLEPPS-----------HPEEPSDLE----EL 187

Query: 147 EQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSFKNMCKLRPLLQK 206
           EQFA+  KQ+RI LG+TQ DVGL +G L+G  FSQ TI RFEAL LSFKNMCKL+PLL+K
Sbjct: 188 EQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEK 247

Query: 207 WVEEADN----------NENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPKPT 256
           W+ +A+           N+        + L   R++KRTSIE  VR  LE  FL   KPT
Sbjct: 248 WLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPT 307

Query: 257 L-QISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPPAP 315
             +I  IA+QL +EK+V+RVWFCNRRQK KR +   A      A   P  G P S+    
Sbjct: 308 SEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSA------APMLPSPGKPASY---- 357

Query: 316 GPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGS 354
            PH  TP  G+        ++P  +       +V TL S
Sbjct: 358 SPHMVTPQGGA-------GTLPLSQASSSLSTTVTTLSS 389


>gi|148664218 POU transcription factor [Homo sapiens]
          Length = 436

 Score =  162 bits (410), Expect = 4e-40
 Identities = 116/308 (37%), Positives = 157/308 (50%), Gaps = 43/308 (13%)

Query: 27  PGWVDPLT-WLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYELCGGMAYCGPQVGVGLV 85
           PG +  ++ +L  Q  PG  G+ P +            P P +  G +    PQ G GL 
Sbjct: 101 PGHLQSVSQFLLSQTQPGQQGLQPNL-----------LPFPQQQSGLLL---PQTGPGLA 146

Query: 86  PQGGLETSQPESEAGVGVESNSNGASPEPCTVPPGAVKLEKEKLEQNPEKSQDIKALQKE 145
            Q       P S     +E++ +   P P  +P      E   LE              E
Sbjct: 147 SQAFGHPGLPGSSLEPHLEASQH--LPVPKHLPSSGGADEPSDLE--------------E 190

Query: 146 LEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSFKNMCKLRPLLQ 205
           LE+FAK  KQ+RI LG+TQ DVGL +G L+G  FSQ TI RFEAL LSFKNMCKL+PLL+
Sbjct: 191 LEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLE 250

Query: 206 KWVEEADNNENLQEICKAET------LMQARKRKRTSIENRVRGNLENLFLQCPKPTL-Q 258
           KW+ +A+++ +   +    +      +   +++KRTSIE  +R  LE  F   PKP+  +
Sbjct: 251 KWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEE 310

Query: 259 ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQR-----EDFEAAGSPFSGGPVSFPP 313
           IS IA+QL +EK+VVRVWFCNRRQK KR +   A        +        S GP+S PP
Sbjct: 311 ISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYNSRLVSPSGSLGPLSVPP 370

Query: 314 APGPHFGT 321
                 GT
Sbjct: 371 VHSTMPGT 378


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score =  134 bits (336), Expect = 2e-31
 Identities = 110/301 (36%), Positives = 147/301 (48%), Gaps = 38/301 (12%)

Query: 2   AGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVG---PGSEVW 58
           AG  A        PGGGG    G  PG           GP GG G GPG G   PG  + 
Sbjct: 134 AGAAAGGGGAHDGPGGGGGPGGGGGPGG----------GPGGGGGGGPGGGGGGPGGGLL 183

Query: 59  GIPPCPPPY-ELCGGMAYCGPQVGVGL---VPQGGLETSQPESEAGVGVESNSNG--ASP 112
           G    P P+    G +++      + +   +P  GL  +     A     + + G  A+ 
Sbjct: 184 GGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAA 243

Query: 113 EPCTVPPGAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILG 172
                  GA  L             D     +ELE FA+  KQ+RI LG TQADVG  L 
Sbjct: 244 SAAAAVVGAAGLAS---------ICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALA 294

Query: 173 VLFGKV-----FSQKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLM 227
            L  K+      SQ TICRFE+L LS  NM  L+P+LQ W+EEA+  +  +++ K E   
Sbjct: 295 NL--KIPGVGSLSQSTICRFESLTLSHNNMIALKPILQAWLEEAEGAQR-EKMNKPELFN 351

Query: 228 QA-RKRKRTSIENRVRGNLENLFLQCPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGK 285
              +KRKRTSI    + +LE  F   P+P+ + I+ IA++L L+K+VVRVWFCN+RQK K
Sbjct: 352 GGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQK 411

Query: 286 R 286
           R
Sbjct: 412 R 412


>gi|170650730 pituitary specific transcription factor 1 isoform beta
           [Homo sapiens]
          Length = 317

 Score =  132 bits (331), Expect = 6e-31
 Identities = 76/152 (50%), Positives = 97/152 (63%), Gaps = 5/152 (3%)

Query: 144 KELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSFKNMCKLRPL 203
           +ELE+FA   K +RI LGYTQ +VG  L  + G  FSQ TICRFE LQLSFKN CKL+ +
Sbjct: 156 RELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAI 215

Query: 204 LQKWVEEADNNENLQEICKAETLMQARKRK-RTSIENRVRGNLENLFLQCPKPTLQ-ISH 261
           L KW+EEA   E +  +   +     RKRK RT+I    +  LE  F +  KP+ Q I  
Sbjct: 216 LSKWLEEA---EQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMR 272

Query: 262 IAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 293
           +A++L LEK+VVRVWFCNRRQ+ KR  +   Q
Sbjct: 273 MAEELNLEKEVVRVWFCNRRQREKRVKTSLNQ 304


>gi|4505955 pituitary specific transcription factor 1 isoform alpha
           [Homo sapiens]
          Length = 291

 Score =  132 bits (331), Expect = 6e-31
 Identities = 76/152 (50%), Positives = 97/152 (63%), Gaps = 5/152 (3%)

Query: 144 KELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSFKNMCKLRPL 203
           +ELE+FA   K +RI LGYTQ +VG  L  + G  FSQ TICRFE LQLSFKN CKL+ +
Sbjct: 130 RELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAI 189

Query: 204 LQKWVEEADNNENLQEICKAETLMQARKRK-RTSIENRVRGNLENLFLQCPKPTLQ-ISH 261
           L KW+EEA   E +  +   +     RKRK RT+I    +  LE  F +  KP+ Q I  
Sbjct: 190 LSKWLEEA---EQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMR 246

Query: 262 IAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 293
           +A++L LEK+VVRVWFCNRRQ+ KR  +   Q
Sbjct: 247 MAEELNLEKEVVRVWFCNRRQREKRVKTSLNQ 278


>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
          Length = 409

 Score =  124 bits (311), Expect = 1e-28
 Identities = 76/156 (48%), Positives = 103/156 (66%), Gaps = 10/156 (6%)

Query: 138 DIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKV-----FSQKTICRFEALQL 192
           D+ A  ++LE FA+  KQ+RI LG TQADVG  L  L  K+      SQ TICRFE+L L
Sbjct: 250 DVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANL--KIPGVGSLSQSTICRFESLTL 307

Query: 193 SFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQA-RKRKRTSIENRVRGNLENLFLQ 251
           S  NM  L+P+LQ W+EEA+ +   +++ K E    A +KRKRTSI    + +LE  F  
Sbjct: 308 SHNNMIALKPILQAWLEEAEKSHR-EKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAI 366

Query: 252 CPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGKR 286
            P+P+ + I+ IA++L L+K+VVRVWFCN+RQK KR
Sbjct: 367 QPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 402


>gi|4505965 POU class 4 homeobox 3 [Homo sapiens]
          Length = 338

 Score =  120 bits (302), Expect = 1e-27
 Identities = 77/161 (47%), Positives = 102/161 (63%), Gaps = 10/161 (6%)

Query: 133 PEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKV-----FSQKTICRF 187
           P    D+++  +ELE FA+  KQ+RI LG TQADVG  L  L  K+      SQ TICRF
Sbjct: 174 PACLSDVESDPRELEAFAERFKQRRIKLGVTQADVGAALANL--KIPGVGSLSQSTICRF 231

Query: 188 EALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLM-QARKRKRTSIENRVRGNLE 246
           E+L LS  NM  L+P+LQ W+EEA+     ++  K E      RKRKRTSI    + +LE
Sbjct: 232 ESLTLSHNNMIALKPVLQAWLEEAEAAYR-EKNSKPELFNGSERKRKRTSIAAPEKRSLE 290

Query: 247 NLFLQCPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGKR 286
             F   P+P+ + I+ IA++L L+K+VVRVWFCN+RQK KR
Sbjct: 291 AYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 331


>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
          Length = 301

 Score =  108 bits (270), Expect = 7e-24
 Identities = 73/210 (34%), Positives = 112/210 (53%), Gaps = 15/210 (7%)

Query: 85  VPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPGAVKLEKEKLEQNPEKSQDIKALQK 144
           VPQ  +  + P   A    + +++   P  C+  P   +L  +     P   +D   L+ 
Sbjct: 93  VPQPAVVIASPAPAA----KPSASAPIPITCSETPTVSQLVSKP--HTPSLDEDGINLE- 145

Query: 145 ELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQLSFKNMCKLRPLL 204
           E+ +FAK  K +R++LG TQ  VG  L    G  +SQ  ICRFE L ++ K+  KL+P+L
Sbjct: 146 EIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVL 205

Query: 205 QKWVEEA-----DNNENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPKPTLQ- 258
           +KW+ EA     +  +NL E    E     ++++RTS   +    L   F + P PT Q 
Sbjct: 206 EKWLNEAELRNQEGQQNLMEFVGGEP--SKKRKRRTSFTPQAIEALNAYFEKNPLPTGQE 263

Query: 259 ISHIAQQLGLEKDVVRVWFCNRRQKGKRSS 288
           I+ IA++L  +++VVRVWFCNRRQ  K +S
Sbjct: 264 ITEIAKELNYDREVVRVWFCNRRQTLKNTS 293


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score = 82.8 bits (203), Expect = 4e-16
 Identities = 90/347 (25%), Positives = 144/347 (41%), Gaps = 68/347 (19%)

Query: 3   GHLASDFAFSPPPGGGGDGPWGAEPGWVDPLT---WLSFQGPPGGPGIGPGVGPGSEVWG 59
           G +       P PG       G +   V P+T     + QG      IG  + P     G
Sbjct: 341 GQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQG 400

Query: 60  IP--PCPPPYELCGGMAYCGPQVGVGLVPQGG----LETSQPE-SEAGVGVESNSNGASP 112
           I   P  P  +L     +   Q  VG     G    L  SQ   S++ V   S+S+ +S 
Sbjct: 401 ITLSPIKPGQQL-----HQPSQTSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSS 455

Query: 113 EPCTVPPGAVKLEKEKLEQNPEKSQ-DIKALQ-KELEQFAKLLKQKRITLGYTQADVGLI 170
               +  G       +L  NP+ +  ++  +  +E+ +FAK  K +R++LG TQ  VG  
Sbjct: 456 SSSALSVG-------QLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQA 508

Query: 171 LGVLFGKVFSQKTICR------------------------------------FEALQLSF 194
           L    G  +SQ  ICR                                    FE L ++ 
Sbjct: 509 LSATEGPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITP 568

Query: 195 KNMCKLRPLLQKWVEEADNN-----ENLQEICKAETLMQARKRKRTSIENRVRGNLENLF 249
           K+  K++P+L++W+ EA+       +NL E   +E     ++++RTS   +    L   F
Sbjct: 569 KSAQKIKPVLERWMAEAEARHRAGMQNLTEFIGSEP--SKKRKRRTSFTPQALEILNAHF 626

Query: 250 LQCPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQRE 295
            +   P+ Q ++ IA++L  +++VVRVWFCN+RQ  K +     Q E
Sbjct: 627 EKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIKRLKQHE 673


>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
          Length = 406

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 6/79 (7%)

Query: 209 EEADNNENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPKPTLQI-SHIAQQLG 267
           +EA +NEN       + L   R+  RT+I+ +    L+  F   PKPT  I   +AQ+ G
Sbjct: 164 KEAGSNEN-----DDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETG 218

Query: 268 LEKDVVRVWFCNRRQKGKR 286
           L   V++VWF NRR K +R
Sbjct: 219 LNMRVIQVWFQNRRSKERR 237


>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
          Length = 402

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 6/79 (7%)

Query: 209 EEADNNENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQCPKPTLQI-SHIAQQLG 267
           +E  NNEN ++    +     R+  RT+I+ +    L+  F   PKPT  I   +AQ+ G
Sbjct: 164 KETANNENEEQNSGTK-----RRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETG 218

Query: 268 LEKDVVRVWFCNRRQKGKR 286
           L   V++VWF NRR K +R
Sbjct: 219 LNMRVIQVWFQNRRSKERR 237


>gi|210147470 NK2 transcription factor related, locus 6 [Homo
           sapiens]
          Length = 219

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 32/96 (33%), Positives = 42/96 (43%), Gaps = 19/96 (19%)

Query: 261 HIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFP-------P 313
           H+A  L L    V++WF NRR K KR   D    +  E AG P +   V+ P       P
Sbjct: 82  HLASALQLTSTQVKIWFQNRRYKCKRQRQD----KSLELAGHPLTPRRVAVPVLVRDGKP 137

Query: 314 APGPHFGTPGYGSPHFTAL--------YSSVPFPEG 341
             GP  G P + SP+  A+        YS  P+  G
Sbjct: 138 CLGPGPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAG 173


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 77/321 (23%), Positives = 122/321 (38%), Gaps = 69/321 (21%)

Query: 60  IPPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPP 119
           +PP P   EL G      P+  +G+    G   S P +  G G E +             
Sbjct: 183 VPPPPALDELGGPGGVTHPEERLGVAGGPG---SAPAAGGGTGTEDD------------- 226

Query: 120 GAVKLEKEKLEQNPEKSQDIKALQKELEQFAK-----LLKQKRITLGYTQADVGLILGVL 174
                E+E LE   ++ ++ + L+ + E+  +     LLK+ R       A  G +    
Sbjct: 227 -----EEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRC---PVAATGAVAAAA 278

Query: 175 FGKVFSQKTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKA------ETLMQ 228
              V +       E  +LS K    L P      E+A+  +    +C +      E L++
Sbjct: 279 AAAVAT-------EGGELSPKEELLLHP------EDAEGKDGEDSVCLSAGSDSEEGLLK 325

Query: 229 ARKRK-RTSIENRVRGNLENLFLQCPKPTLQI-SHIAQQLGLEKDVVRVWFCNRRQKGKR 286
            ++R+ RT+  +     LE  F +   P +     +A +L L +  V+VWF NRR K ++
Sbjct: 326 RKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRK 385

Query: 287 SSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHFGTPGYGSPHFTAL-------------- 332
                AQ       G PF  GP+S      P+     +  PH  AL              
Sbjct: 386 REKAGAQT---HPPGLPFP-GPLSATHPLSPYLDASPF-PPHHPALDSAWTAAAAAAAAA 440

Query: 333 YSSVPFPEGEVFPPVSVITLG 353
           + S+P P G    P S   LG
Sbjct: 441 FPSLPPPPGSASLPPSGAPLG 461


>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
          Length = 390

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 1/61 (1%)

Query: 231 KRKRTSIENRVRGNLENLFLQCPKPTLQI-SHIAQQLGLEKDVVRVWFCNRRQKGKRSSS 289
           KR RT+I  +    L+N +   PKP   +   ++ + GL+  VV+VWF NRR K KR   
Sbjct: 158 KRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217

Query: 290 D 290
           D
Sbjct: 218 D 218


>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
          Length = 397

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 8/84 (9%)

Query: 215 ENLQEICKA--ETLMQAR-----KRKRTSIENRVRGNLENLFLQCPKPTLQI-SHIAQQL 266
           E+ + +CKA  ET  Q       KR RT+I  +    L++ +   PKP   +   ++ + 
Sbjct: 135 EDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSET 194

Query: 267 GLEKDVVRVWFCNRRQKGKRSSSD 290
           GL+  VV+VWF NRR K KR   D
Sbjct: 195 GLDMRVVQVWFQNRRAKEKRLKKD 218


>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
          Length = 402

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 8/84 (9%)

Query: 215 ENLQEICKA--ETLMQAR-----KRKRTSIENRVRGNLENLFLQCPKPTLQI-SHIAQQL 266
           E+ + +CKA  ET  Q       KR RT+I  +    L++ +   PKP   +   ++ + 
Sbjct: 140 EDSRLVCKADYETAKQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSET 199

Query: 267 GLEKDVVRVWFCNRRQKGKRSSSD 290
           GL+  VV+VWF NRR K KR   D
Sbjct: 200 GLDMRVVQVWFQNRRAKEKRLKKD 223


>gi|61969666 arginine-fifty homeobox [Homo sapiens]
          Length = 315

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 7/116 (6%)

Query: 223 AETLMQARKRKRTSIENRVRGNLENLFLQCPKPTLQISH-IAQQLGLEKDVVRVWFCNRR 281
           A T ++ R ++RTS  ++    LE LF Q   P   +   +A +L L +  V+VWF NRR
Sbjct: 71  ATTAIRRRHKERTSFTHQQYEELEALFSQTMFPDRNLQEKLALRLDLPESTVKVWFRNRR 130

Query: 282 QKGKRSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVP 337
            K K+     + ++  +   S     P S   +P P+       SP  +  YSS+P
Sbjct: 131 FKLKKQQQQQSAKQRNQILPSK-KNVPTSPRTSPSPY-----AFSPVISDFYSSLP 180


>gi|11386181 H2.0-like homeobox [Homo sapiens]
          Length = 488

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 32/89 (35%), Positives = 42/89 (47%), Gaps = 5/89 (5%)

Query: 224 ETLMQARKRKRT----SIENRVRGNLENLF-LQCPKPTLQISHIAQQLGLEKDVVRVWFC 278
           +T+ Q  KRKR+       N  R  LE  F +Q          +A  LGL    V+VWF 
Sbjct: 266 DTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQ 325

Query: 279 NRRQKGKRSSSDYAQREDFEAAGSPFSGG 307
           NRR K + S    AQ++  + AG   SGG
Sbjct: 326 NRRMKWRHSKEAQAQKDKDKEAGEKPSGG 354


>gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]
          Length = 571

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 43/158 (27%), Positives = 61/158 (38%), Gaps = 22/158 (13%)

Query: 12  SPPPGGGGDGPWGAEPGWVDPLTWLSFQGP------------PGGPGIGPGVGPGSEVWG 59
           SPPP G   GP GA   W   +   +  GP            PGGPG GPG   G+   G
Sbjct: 64  SPPPQGPLPGPPGALHRWALAVPPGAVAGPRPQQASPPPCGGPGGPGGGPGDALGAAAAG 123

Query: 60  IPPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPP 119
           +          G +   G  VGVG    G   + +     GVG      G SPE   V  
Sbjct: 124 V-------GAAGVVVGVGGAVGVGGCCSGPGHSKRRRQAPGVGA---VGGGSPEREEVGA 173

Query: 120 GAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKR 157
           G    ++ +      ++ D   ++++   F K L+ K+
Sbjct: 174 GYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKK 211


>gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]
          Length = 566

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 43/158 (27%), Positives = 61/158 (38%), Gaps = 22/158 (13%)

Query: 12  SPPPGGGGDGPWGAEPGWVDPLTWLSFQGP------------PGGPGIGPGVGPGSEVWG 59
           SPPP G   GP GA   W   +   +  GP            PGGPG GPG   G+   G
Sbjct: 64  SPPPQGPLPGPPGALHRWALAVPPGAVAGPRPQQASPPPCGGPGGPGGGPGDALGAAAAG 123

Query: 60  IPPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPP 119
           +          G +   G  VGVG    G   + +     GVG      G SPE   V  
Sbjct: 124 V-------GAAGVVVGVGGAVGVGGCCSGPGHSKRRRQAPGVGA---VGGGSPEREEVGA 173

Query: 120 GAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKR 157
           G    ++ +      ++ D   ++++   F K L+ K+
Sbjct: 174 GYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKK 211


>gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]
          Length = 566

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 43/158 (27%), Positives = 61/158 (38%), Gaps = 22/158 (13%)

Query: 12  SPPPGGGGDGPWGAEPGWVDPLTWLSFQGP------------PGGPGIGPGVGPGSEVWG 59
           SPPP G   GP GA   W   +   +  GP            PGGPG GPG   G+   G
Sbjct: 64  SPPPQGPLPGPPGALHRWALAVPPGAVAGPRPQQASPPPCGGPGGPGGGPGDALGAAAAG 123

Query: 60  IPPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPP 119
           +          G +   G  VGVG    G   + +     GVG      G SPE   V  
Sbjct: 124 V-------GAAGVVVGVGGAVGVGGCCSGPGHSKRRRQAPGVGA---VGGGSPEREEVGA 173

Query: 120 GAVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKR 157
           G    ++ +      ++ D   ++++   F K L+ K+
Sbjct: 174 GYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKK 211


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.137    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,939,394
Number of Sequences: 37866
Number of extensions: 1358646
Number of successful extensions: 6938
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 139
Number of HSP's successfully gapped in prelim test: 417
Number of HSP's that attempted gapping in prelim test: 5390
Number of HSP's gapped (non-prelim): 1765
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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