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Search of human proteins with 226497734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226497734 RNA binding motif protein 19 [Homo sapiens]
(960 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226497734 RNA binding motif protein 19 [Homo sapiens] 1907 0.0
gi|226497654 RNA binding motif protein 19 [Homo sapiens] 1907 0.0
gi|226497574 RNA binding motif protein 19 [Homo sapiens] 1907 0.0
gi|187960109 RNA binding motif protein 28 [Homo sapiens] 92 2e-18
gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a ... 83 1e-15
gi|14110414 heterogeneous nuclear ribonucleoprotein D isoform c ... 83 1e-15
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 82 2e-15
gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b ... 81 4e-15
gi|51477708 heterogeneous nuclear ribonucleoprotein D isoform d ... 81 4e-15
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 81 5e-15
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 81 5e-15
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 81 5e-15
gi|55956788 nucleolin [Homo sapiens] 80 7e-15
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 80 9e-15
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 78 5e-14
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 78 5e-14
gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform ... 77 6e-14
gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform ... 77 6e-14
gi|7661952 squamous cell carcinoma antigen recognized by T cells... 75 2e-13
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 74 7e-13
gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo sap... 74 7e-13
gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo sapi... 74 7e-13
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 73 1e-12
gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo sapi... 73 1e-12
gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo... 73 1e-12
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 72 2e-12
gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo sap... 72 3e-12
gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo sap... 72 3e-12
gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo sap... 72 3e-12
gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo sap... 72 3e-12
>gi|226497734 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 1907 bits (4940), Expect = 0.0
Identities = 960/960 (100%), Positives = 960/960 (100%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK
Sbjct: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
Query: 61 HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120
HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV
Sbjct: 61 HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120
Query: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180
AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES
Sbjct: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180
Query: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS
Sbjct: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
Query: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG
Sbjct: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
Query: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360
APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR
Sbjct: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360
Query: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK
Sbjct: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
Query: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480
LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI
Sbjct: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480
Query: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540
KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF
Sbjct: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540
Query: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600
DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA
Sbjct: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600
Query: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660
AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG
Sbjct: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660
Query: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720
VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE
Sbjct: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720
Query: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780
EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE
Sbjct: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780
Query: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840
YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP
Sbjct: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840
Query: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900
FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL
Sbjct: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900
Query: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960
YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL
Sbjct: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960
>gi|226497654 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 1907 bits (4940), Expect = 0.0
Identities = 960/960 (100%), Positives = 960/960 (100%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK
Sbjct: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
Query: 61 HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120
HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV
Sbjct: 61 HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120
Query: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180
AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES
Sbjct: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180
Query: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS
Sbjct: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
Query: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG
Sbjct: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
Query: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360
APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR
Sbjct: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360
Query: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK
Sbjct: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
Query: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480
LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI
Sbjct: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480
Query: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540
KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF
Sbjct: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540
Query: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600
DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA
Sbjct: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600
Query: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660
AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG
Sbjct: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660
Query: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720
VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE
Sbjct: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720
Query: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780
EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE
Sbjct: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780
Query: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840
YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP
Sbjct: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840
Query: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900
FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL
Sbjct: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900
Query: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960
YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL
Sbjct: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960
>gi|226497574 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 1907 bits (4940), Expect = 0.0
Identities = 960/960 (100%), Positives = 960/960 (100%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK
Sbjct: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
Query: 61 HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120
HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV
Sbjct: 61 HFNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV 120
Query: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180
AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES
Sbjct: 121 AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES 180
Query: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS
Sbjct: 181 EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
Query: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG
Sbjct: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
Query: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360
APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR
Sbjct: 301 APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR 360
Query: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK
Sbjct: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
Query: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480
LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI
Sbjct: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTI 480
Query: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540
KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF
Sbjct: 481 KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF 540
Query: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600
DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA
Sbjct: 541 DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA 600
Query: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660
AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG
Sbjct: 601 AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPVG 660
Query: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720
VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE
Sbjct: 661 VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE 720
Query: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780
EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE
Sbjct: 721 EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE 780
Query: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840
YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP
Sbjct: 781 YRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIP 840
Query: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900
FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL
Sbjct: 841 FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL 900
Query: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960
YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL
Sbjct: 901 YGRRLVLEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL 960
>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
Length = 759
Score = 92.0 bits (227), Expect = 2e-18
Identities = 64/250 (25%), Positives = 121/250 (48%), Gaps = 28/250 (11%)
Query: 727 LPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQ 786
+ G TLF+ L E+L+E+FS+VG VK C + +K G GFG+V + E
Sbjct: 1 MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEK---GSKACRGFGYVTFSMLED 57
Query: 787 AQKALKQLQGHVVDGHKLEVRISERATKPAVTLARK---KQVPRKQTTSK---------- 833
Q+ALK++ +G K+ V ++++ + K + P+K+ +K
Sbjct: 58 VQRALKEIT--TFEGCKINVTVAKKKLRNKTKEKGKNENSECPKKEPKAKKAKVADKKAR 115
Query: 834 ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNA 893
+++RN+ F+ +++ +F+ FG + V +P+K G RGFGFV F +A +A
Sbjct: 116 LIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRK--PDGKMRGFGFVQFKNLLEAGKALKG 173
Query: 894 LCHSTHLYGRRLVLEWA-------DSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQL 946
+ + + GR + ++WA D++ K+ H+ KK+ +++ E+
Sbjct: 174 M-NMKEIKGRTVAVDWAVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEE 232
Query: 947 EGSDSDSEEQ 956
D D +++
Sbjct: 233 NDDDDDDDDE 242
Score = 72.8 bits (177), Expect = 1e-12
Identities = 86/353 (24%), Positives = 140/353 (39%), Gaps = 77/353 (21%)
Query: 2 SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
+RLI++NL E+ + +FA FG + + ++ DGK R FGF+ FK+ EA KA K
Sbjct: 114 ARLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKG 173
Query: 62 FNKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKVA 121
N I + V++ A +K K +Q + + E K E KK
Sbjct: 174 MNMKEIKGRTVAVDW-----------AVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKG 222
Query: 122 GQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQESE 181
+ E ++E+ D D + E
Sbjct: 223 REEEDMEEEEN----------------------------------------DDDDDDDDE 242
Query: 182 EEGAGEDL-EEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS 240
E+G +D EEE ++E K V K + + A SS SEE+ +E+ D+G
Sbjct: 243 EDGVFDDEDEEEENIESK--VTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDDGE 300
Query: 241 EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG 300
E + D+S +E++ K + KK+ + P++ E TV +R
Sbjct: 301 ELAQSDTST----EEQEDKAV-----QVSNKKK-------RKLPSDVNEG---KTVFIRN 341
Query: 301 APFNVTEKNVMEFL---APLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL 350
F+ E+ + E L LK V I + + +K G F F +E ++ L
Sbjct: 342 LSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSK-GCAFAQFMTQEAAQKCL 393
Score = 61.6 bits (148), Expect = 3e-09
Identities = 83/366 (22%), Positives = 150/366 (40%), Gaps = 48/366 (13%)
Query: 579 QAAAERSKTVILVKNLPAGTLAAQLQETFGHFGSLGRVLLP---EGGITAI--VEFLEPL 633
+A K ++++NL L+ F FG++ V +P +G + V+F L
Sbjct: 106 KAKVADKKARLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLL 165
Query: 634 EARKAFRHLAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDG 693
EA KA + + + + ++WA K K +DT S + E+
Sbjct: 166 EAGKALKGMNMKEIKGRTVAVDWAVA---------KDKYKDTQSVSAIGEEKSHES---- 212
Query: 694 ETPEDENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKV 753
E+ ++G + + EE ++++++++E ++ FD +E+ + + SKV
Sbjct: 213 --KHQESVKKKGREEEDMEEEENDDDDDDDDE---------EDGVFDDEDEEEENIESKV 261
Query: 754 GTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKL---EVRISE 810
K I K+ K E E++ + DG +L + E
Sbjct: 262 --TKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDS--------IDDGEELAQSDTSTEE 311
Query: 811 RATKPA-VTLARKKQVPRKQTTSK-ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMT 868
+ K V+ +K+++P K + +RN+ F + E+ EL FGELK VR+
Sbjct: 312 QEDKAVQVSNKKKRKLPSDVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLH-P 370
Query: 869 GTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEWADSEVTLQALRRKTAAHFH 928
T +G F F+T++ A++ A G L L+ +V L A+ R AA
Sbjct: 371 DTEHSKGCAFAQFMTQEAAQKCLLAASPENEAGG--LKLDGRQLKVDL-AVTRDEAAKLQ 427
Query: 929 EPPKKK 934
KK
Sbjct: 428 TTKVKK 433
Score = 56.6 bits (135), Expect = 1e-07
Identities = 53/211 (25%), Positives = 98/211 (46%), Gaps = 18/211 (8%)
Query: 302 PFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKT--GYIFVDFSNEEEVKQALKCNREYMGG 359
P + + + E + + PV V G+K G+ +V FS E+V++ALK + G
Sbjct: 12 PPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEITTFEGC 71
Query: 360 RYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESG-------RLFVRNLPYT 412
+ NV K +N TK E ++E A+ RL +RNL +
Sbjct: 72 KI-------NVTVAKKKLRNKTKEKGKNENSECPKKEPKAKKAKVADKKARLIIRNLSFK 124
Query: 413 STEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRM 472
+E+DL+ +F+++G + E++ P K +GF F+ F A KA ++ + +GR
Sbjct: 125 CSEDDLKTVFAQFGAVLEVNIP-RKPDGKMRGFGFVQFKNLLEAGKALKGMNMKEIKGRT 183
Query: 473 LHVLPSTIKKEASEDASALGSSSYKKKKEAQ 503
+ V + K+ +D ++ + +K E++
Sbjct: 184 VAV-DWAVAKDKYKDTQSVSAIGEEKSHESK 213
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/107 (28%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
Query: 700 NPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSC 759
N T+E N +++ ++E + ++ + + L I+NL+F +E+ LK VF++ G V
Sbjct: 84 NKTKEKGKNENSECPKKEPKAKKAKVADKKARLIIRNLSFKCSEDDLKTVFAQFGAVLEV 143
Query: 760 SISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEV 806
+I +K + GFGFV+++ +A KALK + + G + V
Sbjct: 144 NIPRKPDGK----MRGFGFVQFKNLLEAGKALKGMNMKEIKGRTVAV 186
Score = 48.1 bits (113), Expect = 4e-05
Identities = 30/106 (28%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
LFV LP ++ E LE+LFS+ GP+ + + +K +GF ++TF E +A E+
Sbjct: 6 LFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQRALKEI 65
Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSA 509
F+G ++V + KK+ G + + + + KA A
Sbjct: 66 --TTFEGCKINV--TVAKKKLRNKTKEKGKNENSECPKKEPKAKKA 107
Score = 47.4 bits (111), Expect = 7e-05
Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
Query: 397 DLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHA 456
D+ E +F+RNL + S EE+L +L ++G L + + T+ KG AF FM E A
Sbjct: 330 DVNEGKTVFIRNLSFDSEEEELGELLQQFGELKYVRIVLHPDTEHSKGCAFAQFMTQEAA 389
Query: 457 VKAY------SEVDGQVFQGRMLHVLPSTIKKEASE 486
K +E G GR L V + + EA++
Sbjct: 390 QKCLLAASPENEAGGLKLDGRQLKVDLAVTRDEAAK 425
>gi|14110420 heterogeneous nuclear ribonucleoprotein D isoform a
[Homo sapiens]
Length = 355
Score = 82.8 bits (203), Expect = 1e-15
Identities = 60/202 (29%), Positives = 94/202 (46%), Gaps = 24/202 (11%)
Query: 699 ENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKS 758
+N +EG NSS + E + EE + +FI L++DTT++ LK+ FSK G V
Sbjct: 72 KNEEDEGHSNSSPRHSEAATAQREEWK------MFIGGLSWDTTKKDLKDYFSKFGEVVD 125
Query: 759 CSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVT 818
C++ K S GFGFV +++ E K + Q + HKL ++ +
Sbjct: 126 CTL---KLDPITGRSRGFGFVLFKESESVDKVMDQKE------HKLNGKV--------ID 168
Query: 819 LARKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGF 878
R K + K+ KI V + +IRE F FGE++++ LP T RGF F
Sbjct: 169 PKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD-NKTNKRRGFCF 227
Query: 879 VDFLTKQDAKRAFNALCHSTHL 900
+ F ++ K+ H+ L
Sbjct: 228 ITFKEEEPVKKIMEKKYHNVGL 249
Score = 48.1 bits (113), Expect = 4e-05
Identities = 41/205 (20%), Positives = 76/205 (37%), Gaps = 31/205 (15%)
Query: 260 GAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLR----GAPFNVTEKNVMEFLA 315
G+ + +G + E + E T + + G ++ T+K++ ++ +
Sbjct: 59 GSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS 118
Query: 316 PLKPVAIRIVR--NAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTT 373
V ++ G G+ FV F E V + + + G+ I+ R K + T
Sbjct: 119 KFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK 178
Query: 374 KGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHY 433
+ K +FV L + EE + + F +G + +
Sbjct: 179 EPVKK-------------------------IFVGGLSPDTPEEKIREYFGGFGEVESIEL 213
Query: 434 PIDSLTKKPKGFAFITFMFPEHAVK 458
P+D+ T K +GF FITF E K
Sbjct: 214 PMDNKTNKRRGFCFITFKEEEPVKK 238
Score = 42.0 bits (97), Expect = 0.003
Identities = 18/63 (28%), Positives = 35/63 (55%)
Query: 400 ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
E ++F+ L + +T++DL+ FSK+G + + +D +T + +GF F+ F E K
Sbjct: 95 EEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKV 154
Query: 460 YSE 462
+
Sbjct: 155 MDQ 157
Score = 35.0 bits (79), Expect = 0.34
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 3 RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTK-DGKFRKFGFIGFKSEEEAQKA--- 58
++ + L ++ + F+ FG + DC+LK G+ R FGF+ FK E K
Sbjct: 98 KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 157
Query: 59 -QKHFNKSFIDTSR 71
+ N ID R
Sbjct: 158 KEHKLNGKVIDPKR 171
Score = 34.7 bits (78), Expect = 0.44
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKF-TKDGKFRKFGFIGFKSEEEAQK-A 58
+ ++ V L EE+ R+ F FG + L K K R F FI FK EE +K
Sbjct: 181 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM 240
Query: 59 QKHFNKSFIDTSRITVEFCK 78
+K ++ + I V K
Sbjct: 241 EKKYHNVGLSKCEIKVAMSK 260
>gi|14110414 heterogeneous nuclear ribonucleoprotein D isoform c
[Homo sapiens]
Length = 306
Score = 82.8 bits (203), Expect = 1e-15
Identities = 60/202 (29%), Positives = 94/202 (46%), Gaps = 24/202 (11%)
Query: 699 ENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKS 758
+N +EG NSS + E + EE + +FI L++DTT++ LK+ FSK G V
Sbjct: 72 KNEEDEGHSNSSPRHSEAATAQREEWK------MFIGGLSWDTTKKDLKDYFSKFGEVVD 125
Query: 759 CSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVT 818
C++ K S GFGFV +++ E K + Q + HKL ++ +
Sbjct: 126 CTL---KLDPITGRSRGFGFVLFKESESVDKVMDQKE------HKLNGKV--------ID 168
Query: 819 LARKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGF 878
R K + K+ KI V + +IRE F FGE++++ LP T RGF F
Sbjct: 169 PKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD-NKTNKRRGFCF 227
Query: 879 VDFLTKQDAKRAFNALCHSTHL 900
+ F ++ K+ H+ L
Sbjct: 228 ITFKEEEPVKKIMEKKYHNVGL 249
Score = 48.1 bits (113), Expect = 4e-05
Identities = 41/205 (20%), Positives = 76/205 (37%), Gaps = 31/205 (15%)
Query: 260 GAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLR----GAPFNVTEKNVMEFLA 315
G+ + +G + E + E T + + G ++ T+K++ ++ +
Sbjct: 59 GSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS 118
Query: 316 PLKPVAIRIVR--NAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTT 373
V ++ G G+ FV F E V + + + G+ I+ R K + T
Sbjct: 119 KFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK 178
Query: 374 KGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHY 433
+ K +FV L + EE + + F +G + +
Sbjct: 179 EPVKK-------------------------IFVGGLSPDTPEEKIREYFGGFGEVESIEL 213
Query: 434 PIDSLTKKPKGFAFITFMFPEHAVK 458
P+D+ T K +GF FITF E K
Sbjct: 214 PMDNKTNKRRGFCFITFKEEEPVKK 238
Score = 42.0 bits (97), Expect = 0.003
Identities = 18/63 (28%), Positives = 35/63 (55%)
Query: 400 ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
E ++F+ L + +T++DL+ FSK+G + + +D +T + +GF F+ F E K
Sbjct: 95 EEWKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKV 154
Query: 460 YSE 462
+
Sbjct: 155 MDQ 157
Score = 35.0 bits (79), Expect = 0.34
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 3 RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTK-DGKFRKFGFIGFKSEEEAQKA--- 58
++ + L ++ + F+ FG + DC+LK G+ R FGF+ FK E K
Sbjct: 98 KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 157
Query: 59 -QKHFNKSFIDTSR 71
+ N ID R
Sbjct: 158 KEHKLNGKVIDPKR 171
Score = 34.7 bits (78), Expect = 0.44
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKF-TKDGKFRKFGFIGFKSEEEAQK-A 58
+ ++ V L EE+ R+ F FG + L K K R F FI FK EE +K
Sbjct: 181 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM 240
Query: 59 QKHFNKSFIDTSRITVEFCK 78
+K ++ + I V K
Sbjct: 241 EKKYHNVGLSKCEIKVAMSK 260
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 82.0 bits (201), Expect = 2e-15
Identities = 55/188 (29%), Positives = 92/188 (48%), Gaps = 12/188 (6%)
Query: 712 KMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVL 771
K EE E + +F+KN+ D +EKLKE+F + G +S + + +
Sbjct: 181 KFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGK--- 237
Query: 772 LSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTT 831
S GFGFV Y E AQKA+ L G +DG L V +++ + L R+ + R +
Sbjct: 238 -SKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEK 296
Query: 832 SK-----ILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQD 886
S+ I ++N+ + +++E FS+FG + K M G +GFG V F + ++
Sbjct: 297 SRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRA---KVMMEVGQGKGFGVVCFSSFEE 353
Query: 887 AKRAFNAL 894
A +A + +
Sbjct: 354 ATKAVDEM 361
Score = 53.9 bits (128), Expect = 7e-07
Identities = 50/213 (23%), Positives = 97/213 (45%), Gaps = 24/213 (11%)
Query: 270 GKKRPPEARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPV-AIRIVRNA 328
G+ + PE RA + ++ T V ++ ++ ++ + E P +++++R+A
Sbjct: 178 GRFKFPEERAAEVRT---RDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA 234
Query: 329 HGNKTGYIFVDFSNEEEVKQA-LKCNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGR 387
G G+ FV + E ++A L + + + G+ + V R A K + +
Sbjct: 235 SGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGR---------AQKKIERLAE-- 283
Query: 388 ILGENEEEEDLAESGR-----LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKP 442
L E L E R ++++NL T +E L++ FS +G +S ++ +
Sbjct: 284 -LRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQG 340
Query: 443 KGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
KGF + F E A KA E++G++ + LHV
Sbjct: 341 KGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHV 373
Score = 52.4 bits (124), Expect = 2e-06
Identities = 32/89 (35%), Positives = 47/89 (52%), Gaps = 5/89 (5%)
Query: 722 EEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEY 781
+E+ PG ++IKNL+ +EKLKE FS G SIS+ K V GFG V +
Sbjct: 294 KEKSRPPGVPIYIKNLDETINDEKLKEEFSSFG-----SISRAKVMMEVGQGKGFGVVCF 348
Query: 782 RKPEQAQKALKQLQGHVVDGHKLEVRISE 810
E+A KA+ ++ G +V L V + +
Sbjct: 349 SSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
Score = 47.0 bits (110), Expect = 9e-05
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 23/174 (13%)
Query: 732 LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKAL 791
L++ +L+ D TE+ L + F G ++ I + L G+G+V +R P A+ AL
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPL---GYGYVNFRFPADAEWAL 76
Query: 792 KQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIREL 851
+ +++G + S+ + RK I ++N+ +R + L
Sbjct: 77 NTMNFDLINGKPFRLMWSQPDDR-----------LRKSGVGNIFIKNLDKSIDNRALFYL 125
Query: 852 FSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRL 905
FS FG + + ++ G+ +G+ +V F + A RA H+ G RL
Sbjct: 126 FSAFGNILSCKVVCDDNGS---KGYAYVHFDSLAAANRAI------WHMNGVRL 170
Score = 40.8 bits (94), Expect = 0.006
Identities = 19/67 (28%), Positives = 36/67 (53%)
Query: 2 SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
+ + VKN+ + + +E+ ++LF +G + GK + FGF+ +++ E AQKA
Sbjct: 199 TNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLD 258
Query: 62 FNKSFID 68
+ ID
Sbjct: 259 LHGKSID 265
Score = 38.5 bits (88), Expect = 0.030
Identities = 21/73 (28%), Positives = 36/73 (49%)
Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
L+V +L TE+ L K F GPL D +T+ P G+ ++ F FP A A + +
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 464 DGQVFQGRMLHVL 476
+ + G+ ++
Sbjct: 80 NFDLINGKPFRLM 92
Score = 37.0 bits (84), Expect = 0.089
Identities = 19/71 (26%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
+ +KNL + +E+ ++ F++FG+++ + + G+ + FG + F S EEA KA N
Sbjct: 304 IYIKNLDETINDEKLKEEFSSFGSISRAKV-MMEVGQGKGFGVVCFSSFEEATKAVDEMN 362
Query: 64 KSFIDTSRITV 74
+ + + V
Sbjct: 363 GRIVGSKPLHV 373
Score = 32.3 bits (72), Expect = 2.2
Identities = 17/74 (22%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
+ + +KNL + LF+AFG + C + +G + + ++ F S A +A
Sbjct: 105 VGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGS-KGYAYVHFDSLAAANRAIW 163
Query: 61 HFNKSFIDTSRITV 74
H N ++ ++ V
Sbjct: 164 HMNGVRLNNRQVYV 177
>gi|14110417 heterogeneous nuclear ribonucleoprotein D isoform b
[Homo sapiens]
Length = 336
Score = 81.3 bits (199), Expect = 4e-15
Identities = 60/200 (30%), Positives = 96/200 (48%), Gaps = 26/200 (13%)
Query: 702 TEEG-ADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCS 760
TE G A++ AK++ + EE+E + +FI L++DTT++ LK+ FSK G V C+
Sbjct: 56 TEGGSAESEGAKIDASKNEEDEGK-------MFIGGLSWDTTKKDLKDYFSKFGEVVDCT 108
Query: 761 ISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLA 820
+ K S GFGFV +++ E K + Q + HKL ++ +
Sbjct: 109 L---KLDPITGRSRGFGFVLFKESESVDKVMDQKE------HKLNGKV--------IDPK 151
Query: 821 RKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVD 880
R K + K+ KI V + +IRE F FGE++++ LP T RGF F+
Sbjct: 152 RAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD-NKTNKRRGFCFIT 210
Query: 881 FLTKQDAKRAFNALCHSTHL 900
F ++ K+ H+ L
Sbjct: 211 FKEEEPVKKIMEKKYHNVGL 230
Score = 54.3 bits (129), Expect = 5e-07
Identities = 51/224 (22%), Positives = 86/224 (38%), Gaps = 29/224 (12%)
Query: 239 GSEAEEEDS--SATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTV 296
GS E+E + +AT GAG G +G A +E K K +
Sbjct: 21 GSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGKM 80
Query: 297 KLRGAPFNVTEKNVMEFLAPLKPVAIRIVR--NAHGNKTGYIFVDFSNEEEVKQALKCNR 354
+ G ++ T+K++ ++ + V ++ G G+ FV F E V + +
Sbjct: 81 FIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKE 140
Query: 355 EYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTST 414
+ G+ I+ R K + T + K +FV L +
Sbjct: 141 HKLNGKVIDPKRAKAMKTKEPVKK-------------------------IFVGGLSPDTP 175
Query: 415 EEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVK 458
EE + + F +G + + P+D+ T K +GF FITF E K
Sbjct: 176 EEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK 219
Score = 48.5 bits (114), Expect = 3e-05
Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 372 TTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSEL 431
T G + + +G + ++ EED G++F+ L + +T++DL+ FSK+G + +
Sbjct: 51 TASGGTEGGSAESEGAKIDASKNEED---EGKMFIGGLSWDTTKKDLKDYFSKFGEVVDC 107
Query: 432 HYPIDSLTKKPKGFAFITFMFPEHAVKAYSE 462
+D +T + +GF F+ F E K +
Sbjct: 108 TLKLDPITGRSRGFGFVLFKESESVDKVMDQ 138
Score = 35.0 bits (79), Expect = 0.34
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 3 RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTK-DGKFRKFGFIGFKSEEEAQKA--- 58
++ + L ++ + F+ FG + DC+LK G+ R FGF+ FK E K
Sbjct: 79 KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 138
Query: 59 -QKHFNKSFIDTSR 71
+ N ID R
Sbjct: 139 KEHKLNGKVIDPKR 152
Score = 34.7 bits (78), Expect = 0.44
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKF-TKDGKFRKFGFIGFKSEEEAQK-A 58
+ ++ V L EE+ R+ F FG + L K K R F FI FK EE +K
Sbjct: 162 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM 221
Query: 59 QKHFNKSFIDTSRITVEFCK 78
+K ++ + I V K
Sbjct: 222 EKKYHNVGLSKCEIKVAMSK 241
>gi|51477708 heterogeneous nuclear ribonucleoprotein D isoform d
[Homo sapiens]
Length = 287
Score = 81.3 bits (199), Expect = 4e-15
Identities = 60/200 (30%), Positives = 96/200 (48%), Gaps = 26/200 (13%)
Query: 702 TEEG-ADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCS 760
TE G A++ AK++ + EE+E + +FI L++DTT++ LK+ FSK G V C+
Sbjct: 56 TEGGSAESEGAKIDASKNEEDEGK-------MFIGGLSWDTTKKDLKDYFSKFGEVVDCT 108
Query: 761 ISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLA 820
+ K S GFGFV +++ E K + Q + HKL ++ +
Sbjct: 109 L---KLDPITGRSRGFGFVLFKESESVDKVMDQKE------HKLNGKV--------IDPK 151
Query: 821 RKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVD 880
R K + K+ KI V + +IRE F FGE++++ LP T RGF F+
Sbjct: 152 RAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMD-NKTNKRRGFCFIT 210
Query: 881 FLTKQDAKRAFNALCHSTHL 900
F ++ K+ H+ L
Sbjct: 211 FKEEEPVKKIMEKKYHNVGL 230
Score = 54.3 bits (129), Expect = 5e-07
Identities = 51/224 (22%), Positives = 86/224 (38%), Gaps = 29/224 (12%)
Query: 239 GSEAEEEDS--SATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTV 296
GS E+E + +AT GAG G +G A +E K K +
Sbjct: 21 GSAGEQEGAMVAATQGAAAAAGSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGKM 80
Query: 297 KLRGAPFNVTEKNVMEFLAPLKPVAIRIVR--NAHGNKTGYIFVDFSNEEEVKQALKCNR 354
+ G ++ T+K++ ++ + V ++ G G+ FV F E V + +
Sbjct: 81 FIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKE 140
Query: 355 EYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTST 414
+ G+ I+ R K + T + K +FV L +
Sbjct: 141 HKLNGKVIDPKRAKAMKTKEPVKK-------------------------IFVGGLSPDTP 175
Query: 415 EEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVK 458
EE + + F +G + + P+D+ T K +GF FITF E K
Sbjct: 176 EEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK 219
Score = 48.5 bits (114), Expect = 3e-05
Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 372 TTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSEL 431
T G + + +G + ++ EED G++F+ L + +T++DL+ FSK+G + +
Sbjct: 51 TASGGTEGGSAESEGAKIDASKNEED---EGKMFIGGLSWDTTKKDLKDYFSKFGEVVDC 107
Query: 432 HYPIDSLTKKPKGFAFITFMFPEHAVKAYSE 462
+D +T + +GF F+ F E K +
Sbjct: 108 TLKLDPITGRSRGFGFVLFKESESVDKVMDQ 138
Score = 35.0 bits (79), Expect = 0.34
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 3 RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTK-DGKFRKFGFIGFKSEEEAQKA--- 58
++ + L ++ + F+ FG + DC+LK G+ R FGF+ FK E K
Sbjct: 79 KMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQ 138
Query: 59 -QKHFNKSFIDTSR 71
+ N ID R
Sbjct: 139 KEHKLNGKVIDPKR 152
Score = 34.7 bits (78), Expect = 0.44
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKF-TKDGKFRKFGFIGFKSEEEAQK-A 58
+ ++ V L EE+ R+ F FG + L K K R F FI FK EE +K
Sbjct: 162 VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIM 221
Query: 59 QKHFNKSFIDTSRITVEFCK 78
+K ++ + I V K
Sbjct: 222 EKKYHNVGLSKCEIKVAMSK 241
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 80.9 bits (198), Expect = 5e-15
Identities = 57/210 (27%), Positives = 99/210 (47%), Gaps = 28/210 (13%)
Query: 702 TEEGADNSSAKME----------------EEEEEEEEEEESLPGCTLFIKNLNFDTTEEK 745
T+E AD + KM +E E E ++ ++IKN + +E
Sbjct: 147 TQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDES 206
Query: 746 LKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLE 805
LKE+FS+ G S + + N S GFGFV Y K E A KA++++ G + G +
Sbjct: 207 LKELFSQFGKTLSVKVMRDPNGK----SKGFGFVSYEKHEDANKAVEEMNGKEISGKIIF 262
Query: 806 VRISERATKPAVTLARKKQVPRKQTTSK-----ILVRNIPFQAHSREIRELFSTFGELKT 860
V +++ + L RK + +++ S+ + ++N+ ++R+ FS FG + +
Sbjct: 263 VGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITS 322
Query: 861 VRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
K M G +GFGFV F + ++A +A
Sbjct: 323 A---KVMLEDGRSKGFGFVCFSSPEEATKA 349
Score = 77.8 bits (190), Expect = 5e-14
Identities = 85/410 (20%), Positives = 162/410 (39%), Gaps = 54/410 (13%)
Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
L+V +L TE L + FS GP+ + D +T++ G+A++ F P A +A +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
+ V +G+ + ++ S +++ S S +G+ K ++ D N A ++T N
Sbjct: 73 NFDVIKGKPIRIMWS--QRDPSLRKSGVGNVFIKNLDKSID--NKAL---YDTFSAFGNI 125
Query: 524 VADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAE 583
++ + N +K F H A + ++ R+ + S
Sbjct: 126 LSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGA 185
Query: 584 RSK--TVILVKNLPAGTLAAQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRH 641
++K T + +KN L+E F FG ++ +P K F
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKT----------LSVKVMRDPNGKSKGFGF 235
Query: 642 LAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENP 701
++Y K + E M + + G
Sbjct: 236 VSYEKHEDA-----------------------NKAVEEMNGKEISGKIIFVGRA------ 266
Query: 702 TEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSI 761
++ + + + E+ ++E G L+IKNL+ +EKL++ FS G++ S +
Sbjct: 267 -QKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKV 325
Query: 762 SKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISER 811
+ + S GFGFV + PE+A KA+ ++ G +V L V +++R
Sbjct: 326 MLEDGR-----SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Score = 66.6 bits (161), Expect = 1e-10
Identities = 52/208 (25%), Positives = 104/208 (50%), Gaps = 18/208 (8%)
Query: 280 ETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPL-KPVAIRIVRNAHGNKTGYIFV 338
E E A KE T V ++ V ++++ E + K ++++++R+ +G G+ FV
Sbjct: 180 EAELGAKAKEFTN---VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFV 236
Query: 339 DFSNEEEVKQALK-CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEED 397
+ E+ +A++ N + + G+ I V R A K + + + E ++E
Sbjct: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGR---------AQKKVERQAELKRKFEQLKQER 287
Query: 398 LA--ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEH 455
++ + L+++NL T +E L K FS +G ++ ++ + KGF F+ F PE
Sbjct: 288 ISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEE 345
Query: 456 AVKAYSEVDGQVFQGRMLHVLPSTIKKE 483
A KA +E++G++ + L+V + K+E
Sbjct: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEE 373
Score = 62.4 bits (150), Expect = 2e-09
Identities = 41/169 (24%), Positives = 82/169 (48%), Gaps = 17/169 (10%)
Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
S P +L++ +L+ D TE L E FS G V S + + S+G+ +V +++P
Sbjct: 7 SYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRR---SLGYAYVNFQQPA 63
Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
A++AL + V+ G + + S+R P++ RK + ++N+ +
Sbjct: 64 DAERALDTMNFDVIKGKPIRIMWSQR--DPSL---------RKSGVGNVFIKNLDKSIDN 112
Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
+ + + FS FG + + ++ G+ +G+ FV F T++ A +A +
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGS---KGYAFVHFETQEAADKAIEKM 158
Score = 47.8 bits (112), Expect = 5e-05
Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
L +KNL + + +E+ R+ F+ FG++T + +DG+ + FGF+ F S EEA KA N
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVML-EDGRSKGFGFVCFSSPEEATKAVTEMN 354
Query: 64 KSFIDTSRITV 74
+ + + V
Sbjct: 355 GRIVGSKPLYV 365
Score = 40.8 bits (94), Expect = 0.006
Identities = 17/62 (27%), Positives = 33/62 (53%)
Query: 2 SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
+ + +KN + +E ++LF+ FG + +GK + FGF+ ++ E+A KA +
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEE 250
Query: 62 FN 63
N
Sbjct: 251 MN 252
Score = 38.5 bits (88), Expect = 0.030
Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
+ + +KNL + + F+AFG + C + ++G + + F+ F+++E A KA +
Sbjct: 98 VGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIE 156
Query: 61 HFNKSFIDTSRITVEFCKS 79
N ++ ++ V KS
Sbjct: 157 KMNGMLLNDRKVFVGRFKS 175
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 80.9 bits (198), Expect = 5e-15
Identities = 57/210 (27%), Positives = 99/210 (47%), Gaps = 28/210 (13%)
Query: 702 TEEGADNSSAKME----------------EEEEEEEEEEESLPGCTLFIKNLNFDTTEEK 745
T+E AD + KM +E E E ++ ++IKN + +E
Sbjct: 147 TQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDES 206
Query: 746 LKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLE 805
LKE+FS+ G S + + N S GFGFV Y K E A KA++++ G + G +
Sbjct: 207 LKELFSQFGKTLSVKVMRDPNGK----SKGFGFVSYEKHEDANKAVEEMNGKEISGKIIF 262
Query: 806 VRISERATKPAVTLARKKQVPRKQTTSK-----ILVRNIPFQAHSREIRELFSTFGELKT 860
V +++ + L RK + +++ S+ + ++N+ ++R+ FS FG + +
Sbjct: 263 VGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITS 322
Query: 861 VRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
K M G +GFGFV F + ++A +A
Sbjct: 323 A---KVMLEDGRSKGFGFVCFSSPEEATKA 349
Score = 77.8 bits (190), Expect = 5e-14
Identities = 85/410 (20%), Positives = 162/410 (39%), Gaps = 54/410 (13%)
Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
L+V +L TE L + FS GP+ + D +T++ G+A++ F P A +A +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
+ V +G+ + ++ S +++ S S +G+ K ++ D N A ++T N
Sbjct: 73 NFDVIKGKPIRIMWS--QRDPSLRKSGVGNVFIKNLDKSID--NKAL---YDTFSAFGNI 125
Query: 524 VADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAE 583
++ + N +K F H A + ++ R+ + S
Sbjct: 126 LSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGA 185
Query: 584 RSK--TVILVKNLPAGTLAAQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRH 641
++K T + +KN L+E F FG ++ +P K F
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKT----------LSVKVMRDPNGKSKGFGF 235
Query: 642 LAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENP 701
++Y K + E M + + G
Sbjct: 236 VSYEKHEDA-----------------------NKAVEEMNGKEISGKIIFVGRA------ 266
Query: 702 TEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSI 761
++ + + + E+ ++E G L+IKNL+ +EKL++ FS G++ S +
Sbjct: 267 -QKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKV 325
Query: 762 SKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISER 811
+ + S GFGFV + PE+A KA+ ++ G +V L V +++R
Sbjct: 326 MLEDGR-----SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Score = 66.6 bits (161), Expect = 1e-10
Identities = 52/208 (25%), Positives = 104/208 (50%), Gaps = 18/208 (8%)
Query: 280 ETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPL-KPVAIRIVRNAHGNKTGYIFV 338
E E A KE T V ++ V ++++ E + K ++++++R+ +G G+ FV
Sbjct: 180 EAELGAKAKEFTN---VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFV 236
Query: 339 DFSNEEEVKQALK-CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEED 397
+ E+ +A++ N + + G+ I V R A K + + + E ++E
Sbjct: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGR---------AQKKVERQAELKRKFEQLKQER 287
Query: 398 LA--ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEH 455
++ + L+++NL T +E L K FS +G ++ ++ + KGF F+ F PE
Sbjct: 288 ISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEE 345
Query: 456 AVKAYSEVDGQVFQGRMLHVLPSTIKKE 483
A KA +E++G++ + L+V + K+E
Sbjct: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEE 373
Score = 62.4 bits (150), Expect = 2e-09
Identities = 41/169 (24%), Positives = 82/169 (48%), Gaps = 17/169 (10%)
Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
S P +L++ +L+ D TE L E FS G V S + + S+G+ +V +++P
Sbjct: 7 SYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRR---SLGYAYVNFQQPA 63
Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
A++AL + V+ G + + S+R P++ RK + ++N+ +
Sbjct: 64 DAERALDTMNFDVIKGKPIRIMWSQR--DPSL---------RKSGVGNVFIKNLDKSIDN 112
Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
+ + + FS FG + + ++ G+ +G+ FV F T++ A +A +
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGS---KGYAFVHFETQEAADKAIEKM 158
Score = 47.8 bits (112), Expect = 5e-05
Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
L +KNL + + +E+ R+ F+ FG++T + +DG+ + FGF+ F S EEA KA N
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVML-EDGRSKGFGFVCFSSPEEATKAVTEMN 354
Query: 64 KSFIDTSRITV 74
+ + + V
Sbjct: 355 GRIVGSKPLYV 365
Score = 40.8 bits (94), Expect = 0.006
Identities = 17/62 (27%), Positives = 33/62 (53%)
Query: 2 SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
+ + +KN + +E ++LF+ FG + +GK + FGF+ ++ E+A KA +
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEE 250
Query: 62 FN 63
N
Sbjct: 251 MN 252
Score = 38.5 bits (88), Expect = 0.030
Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
+ + +KNL + + F+AFG + C + ++G + + F+ F+++E A KA +
Sbjct: 98 VGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIE 156
Query: 61 HFNKSFIDTSRITVEFCKS 79
N ++ ++ V KS
Sbjct: 157 KMNGMLLNDRKVFVGRFKS 175
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 80.9 bits (198), Expect = 5e-15
Identities = 57/210 (27%), Positives = 99/210 (47%), Gaps = 28/210 (13%)
Query: 702 TEEGADNSSAKME----------------EEEEEEEEEEESLPGCTLFIKNLNFDTTEEK 745
T+E AD + KM +E E E ++ ++IKN + +E
Sbjct: 147 TQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDES 206
Query: 746 LKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLE 805
LKE+FS+ G S + + N S GFGFV Y K E A KA++++ G + G +
Sbjct: 207 LKELFSQFGKTLSVKVMRDPNGK----SKGFGFVSYEKHEDANKAVEEMNGKEISGKIIF 262
Query: 806 VRISERATKPAVTLARKKQVPRKQTTSK-----ILVRNIPFQAHSREIRELFSTFGELKT 860
V +++ + L RK + +++ S+ + ++N+ ++R+ FS FG + +
Sbjct: 263 VGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITS 322
Query: 861 VRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
K M G +GFGFV F + ++A +A
Sbjct: 323 A---KVMLEDGRSKGFGFVCFSSPEEATKA 349
Score = 77.8 bits (190), Expect = 5e-14
Identities = 85/410 (20%), Positives = 162/410 (39%), Gaps = 54/410 (13%)
Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
L+V +L TE L + FS GP+ + D +T++ G+A++ F P A +A +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
+ V +G+ + ++ S +++ S S +G+ K ++ D N A ++T N
Sbjct: 73 NFDVIKGKPIRIMWS--QRDPSLRKSGVGNVFIKNLDKSID--NKAL---YDTFSAFGNI 125
Query: 524 VADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAE 583
++ + N +K F H A + ++ R+ + S
Sbjct: 126 LSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGA 185
Query: 584 RSK--TVILVKNLPAGTLAAQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRH 641
++K T + +KN L+E F FG ++ +P K F
Sbjct: 186 KAKEFTNVYIKNFGEEVDDESLKELFSQFGKT----------LSVKVMRDPNGKSKGFGF 235
Query: 642 LAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENP 701
++Y K + E M + + G
Sbjct: 236 VSYEKHEDA-----------------------NKAVEEMNGKEISGKIIFVGRA------ 266
Query: 702 TEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSI 761
++ + + + E+ ++E G L+IKNL+ +EKL++ FS G++ S +
Sbjct: 267 -QKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKV 325
Query: 762 SKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISER 811
+ + S GFGFV + PE+A KA+ ++ G +V L V +++R
Sbjct: 326 MLEDGR-----SKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQR 370
Score = 66.6 bits (161), Expect = 1e-10
Identities = 52/208 (25%), Positives = 104/208 (50%), Gaps = 18/208 (8%)
Query: 280 ETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPL-KPVAIRIVRNAHGNKTGYIFV 338
E E A KE T V ++ V ++++ E + K ++++++R+ +G G+ FV
Sbjct: 180 EAELGAKAKEFTN---VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFV 236
Query: 339 DFSNEEEVKQALK-CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEED 397
+ E+ +A++ N + + G+ I V R A K + + + E ++E
Sbjct: 237 SYEKHEDANKAVEEMNGKEISGKIIFVGR---------AQKKVERQAELKRKFEQLKQER 287
Query: 398 LA--ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEH 455
++ + L+++NL T +E L K FS +G ++ ++ + KGF F+ F PE
Sbjct: 288 ISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEE 345
Query: 456 AVKAYSEVDGQVFQGRMLHVLPSTIKKE 483
A KA +E++G++ + L+V + K+E
Sbjct: 346 ATKAVTEMNGRIVGSKPLYVALAQRKEE 373
Score = 62.4 bits (150), Expect = 2e-09
Identities = 41/169 (24%), Positives = 82/169 (48%), Gaps = 17/169 (10%)
Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
S P +L++ +L+ D TE L E FS G V S + + S+G+ +V +++P
Sbjct: 7 SYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRR---SLGYAYVNFQQPA 63
Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
A++AL + V+ G + + S+R P++ RK + ++N+ +
Sbjct: 64 DAERALDTMNFDVIKGKPIRIMWSQR--DPSL---------RKSGVGNVFIKNLDKSIDN 112
Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
+ + + FS FG + + ++ G+ +G+ FV F T++ A +A +
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGS---KGYAFVHFETQEAADKAIEKM 158
Score = 47.8 bits (112), Expect = 5e-05
Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
L +KNL + + +E+ R+ F+ FG++T + +DG+ + FGF+ F S EEA KA N
Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVML-EDGRSKGFGFVCFSSPEEATKAVTEMN 354
Query: 64 KSFIDTSRITV 74
+ + + V
Sbjct: 355 GRIVGSKPLYV 365
Score = 40.8 bits (94), Expect = 0.006
Identities = 17/62 (27%), Positives = 33/62 (53%)
Query: 2 SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
+ + +KN + +E ++LF+ FG + +GK + FGF+ ++ E+A KA +
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEE 250
Query: 62 FN 63
N
Sbjct: 251 MN 252
Score = 38.5 bits (88), Expect = 0.030
Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
+ + +KNL + + F+AFG + C + ++G + + F+ F+++E A KA +
Sbjct: 98 VGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIE 156
Query: 61 HFNKSFIDTSRITVEFCKS 79
N ++ ++ V KS
Sbjct: 157 KMNGMLLNDRKVFVGRFKS 175
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 80.5 bits (197), Expect = 7e-15
Identities = 87/395 (22%), Positives = 169/395 (42%), Gaps = 39/395 (9%)
Query: 128 KEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQESEEEGAG- 186
KED++ +E + D + EP+ K+ A+ + D E +E+
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201
Query: 187 -EDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEE 245
ED EE ++E A K+ + + +K+K V ++E+ +D+ DE + E++
Sbjct: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDD 261
Query: 246 DSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRGAPFNV 305
+ +E + G+ + A +K PEA+ ++ EPTT + + FN
Sbjct: 262 EEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAK---KQKVEGTEPTTAFNLFVGNLNFNK 318
Query: 306 TEKNVMEFLAPL---KPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYI 362
+ + ++ + +A+ VR K GY VDF + E++++AL+ + G I
Sbjct: 319 SAPELKTGISDVFAKNDLAVVDVRIGMTRKFGY--VDFESAEDLEKALELTGLKVFGNEI 376
Query: 363 EVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLF 422
++ + K G++ ++E ++ L +NLPY T+++L+++F
Sbjct: 377 KLEKPK---------------------GKDSKKE--RDARTLLAKNLPYKVTQDELKEVF 413
Query: 423 SKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKK 482
+ + S K KG A+I F A K + E G GR + L T +K
Sbjct: 414 EDAAEIR-----LVSKDGKSKGIAYIEFKTEADAEKTFEEKQGTEIDGRSIS-LYYTGEK 467
Query: 483 EASEDASALGSSSYKKKKEAQDKANSASSHNWNTL 517
++D +S++ + + +N + S TL
Sbjct: 468 GQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETL 502
Score = 76.3 bits (186), Expect = 1e-13
Identities = 66/272 (24%), Positives = 117/272 (43%), Gaps = 52/272 (19%)
Query: 665 TAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEE 724
T P K K K+ AE E + + ED++ E+ D+ EEEEEEEEEE
Sbjct: 213 TTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEP 272
Query: 725 -----------------------------ESLPGCTLFIKNLNFDTTEEKLKEVFSKVGT 755
E LF+ NLNF+ + +LK S V
Sbjct: 273 VKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFA 332
Query: 756 VKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKP 815
++ + + ++ FG+V++ E +KAL +L G V G+++++ KP
Sbjct: 333 KNDLAVVDVR----IGMTRKFGYVDFESAEDLEKAL-ELTGLKVFGNEIKLE------KP 381
Query: 816 AVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRG 875
+ K +++ +L +N+P++ E++E+F E++ V + G +G
Sbjct: 382 -----KGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLV------SKDGKSKG 430
Query: 876 FGFVDFLTKQDAKRAFNALCHSTHLYGRRLVL 907
+++F T+ DA++ F T + GR + L
Sbjct: 431 IAYIEFKTEADAEKTFEEK-QGTEIDGRSISL 461
Score = 70.1 bits (170), Expect = 9e-12
Identities = 48/180 (26%), Positives = 84/180 (46%), Gaps = 21/180 (11%)
Query: 731 TLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKA 790
TL + NL++ TEE L+EVF K +K K+K G+ F+E+ E A++A
Sbjct: 487 TLVLSNLSYSATEETLQEVFEKATFIKVPQNQNGKSK-------GYAFIEFASFEDAKEA 539
Query: 791 LKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
L ++G + + + P R Q + + V+ + ++E
Sbjct: 540 LNSCNKREIEGRAIRLELQGPRGSPNA---------RSQPSKTLFVKGLSEDTTEETLKE 590
Query: 851 LFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEWA 910
F G ++ + + TG+ +GFGFVDF +++DAK A A+ + G ++ L+WA
Sbjct: 591 SFD--GSVRARIVTDRETGSS--KGFGFVDFNSEEDAKAAKEAM-EDGEIDGNKVTLDWA 645
Score = 67.8 bits (164), Expect = 5e-11
Identities = 46/197 (23%), Positives = 95/197 (48%), Gaps = 17/197 (8%)
Query: 712 KMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVL 771
K+E+ + ++ ++E TL KNL + T+++LKEVF ++ S K
Sbjct: 377 KLEKPKGKDSKKERDAR--TLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGK------- 427
Query: 772 LSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTT 831
S G ++E++ A+K ++ QG +DG + + + + K ++
Sbjct: 428 -SKGIAYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESK 486
Query: 832 SKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAF 891
+ +L N+ + A ++E+F + +++P+ G +G+ F++F + +DAK A
Sbjct: 487 TLVL-SNLSYSATEETLQEVFE---KATFIKVPQNQNGKS--KGYAFIEFASFEDAKEAL 540
Query: 892 NALCHSTHLYGRRLVLE 908
N+ C+ + GR + LE
Sbjct: 541 NS-CNKREIEGRAIRLE 556
Score = 55.5 bits (132), Expect = 2e-07
Identities = 94/402 (23%), Positives = 157/402 (39%), Gaps = 57/402 (14%)
Query: 94 QKPSQPKQPPKDSTTPEIKKDEKKKKVAGQLEKLKED-----TEFQEF---LSVHQRRAQ 145
++ + ++ P + KK+ K+K A + +K K + T F F L+ ++ +
Sbjct: 263 EEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSAPE 322
Query: 146 AAT-----WANDGLDAEPSKGKSKPASDYLNFDSDSGQESEEEGAG-EDLEEEASLE-PK 198
T +A + L + Y++F+S E E G + E LE PK
Sbjct: 323 LKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPK 382
Query: 199 AAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEEDSSATPVLQERDS 258
K+ D L +K + + +E ED A + + + + E D+
Sbjct: 383 GKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVSKDGKSKGIAYIEFKTEADA 442
Query: 259 KGAGQEQGMPAGKKRPPEARAETEKPANQ-----KEPT---TCHTVKLRGAPFNVTEKNV 310
+ +E+ R EK NQ K T T+ L ++ TE+ +
Sbjct: 443 EKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETL 502
Query: 311 MEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL-KCNREYMGGRYI--EVFRE 367
E K I++ +N +G GY F++F++ E+ K+AL CN+ + GR I E+
Sbjct: 503 QEVFE--KATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGP 560
Query: 368 KNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGP 427
+ P + P T LFV+ L +TEE L++ F G
Sbjct: 561 RGSPNARSQPSKT-----------------------LFVKGLSEDTTEETLKESFD--GS 595
Query: 428 LSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV--DGQV 467
+ D T KGF F+ F E A KA E DG++
Sbjct: 596 V-RARIVTDRETGSSKGFGFVDFNSEEDA-KAAKEAMEDGEI 635
Score = 54.3 bits (129), Expect = 5e-07
Identities = 31/98 (31%), Positives = 55/98 (56%), Gaps = 6/98 (6%)
Query: 707 DNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKN 766
+ + ++E + S P TLF+K L+ DTTEE LKE F G+V++ ++ ++
Sbjct: 549 EGRAIRLELQGPRGSPNARSQPSKTLFVKGLSEDTTEETLKESFD--GSVRARIVTDRET 606
Query: 767 KAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKL 804
+ S GFGFV++ E A+ A + ++ +DG+K+
Sbjct: 607 GS----SKGFGFVDFNSEEDAKAAKEAMEDGEIDGNKV 640
Score = 53.1 bits (126), Expect = 1e-06
Identities = 51/203 (25%), Positives = 90/203 (44%), Gaps = 25/203 (12%)
Query: 276 EARAETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGY 335
E + E K + K+ T+ + P+ VT+ + E IR+V + G G
Sbjct: 375 EIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDA--AEIRLV-SKDGKSKGI 431
Query: 336 IFVDFSNEEEVKQALKCNR-EYMGGRYIEVFR--EKNVPTTKGAPKNTTKSWQGRILGEN 392
+++F E + ++ + + + GR I ++ EK KN+T W G
Sbjct: 432 AYIEFKTEADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYRGGKNST--WSG------ 483
Query: 393 EEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMF 452
ES L + NL Y++TEE L+++F K + + P + K KG+AFI F
Sbjct: 484 -------ESKTLVLSNLSYSATEETLQEVFEK---ATFIKVP-QNQNGKSKGYAFIEFAS 532
Query: 453 PEHAVKAYSEVDGQVFQGRMLHV 475
E A +A + + + +GR + +
Sbjct: 533 FEDAKEALNSCNKREIEGRAIRL 555
Score = 40.4 bits (93), Expect = 0.008
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
L VK L EE ++ F G++ + + G + FGF+ F SEE+A+ A++
Sbjct: 574 LFVKGLSEDTTEETLKESFD--GSVRARIVTDRETGSSKGFGFVDFNSEEDAKAAKEAME 631
Query: 64 KSFIDTSRITVEFCKSFGD 82
ID +++T+++ K G+
Sbjct: 632 DGEIDGNKVTLDWAKPKGE 650
Score = 35.8 bits (81), Expect = 0.20
Identities = 57/266 (21%), Positives = 109/266 (40%), Gaps = 43/266 (16%)
Query: 666 APQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEE 725
A K + S+ E D +E + D + EDE+ E A ++A E+E++E++E
Sbjct: 134 AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193
Query: 726 SLPGCTLFIKNLNFDTTEEKLKEV-------FSKVGTVKSCSISKKKNKAGVLLSMGFG- 777
+ D +EE+ E +KV VK+ ++++ +++
Sbjct: 194 DDED----DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD 249
Query: 778 ----------FVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPR 827
E + E+ ++ +K+ G R E A + A A+K++V
Sbjct: 250 DEDDEDDDDEDDEEEEEEEEEEPVKEAPGK---------RKKEMAKQKAAPEAKKQKVEG 300
Query: 828 KQTTS--KILVRNIPFQAHSREIRELFSTF---GELKTVRLPKKMTGTGTHRGFGFVDFL 882
+ T+ + V N+ F + E++ S +L V + MT R FG+VDF
Sbjct: 301 TEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMT-----RKFGYVDFE 355
Query: 883 TKQDAKRAFNALCHSTHLYGRRLVLE 908
+ +D ++A ++G + LE
Sbjct: 356 SAEDLEKALELT--GLKVFGNEIKLE 379
Score = 34.3 bits (77), Expect = 0.57
Identities = 58/280 (20%), Positives = 103/280 (36%), Gaps = 26/280 (9%)
Query: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
L+ KNLP + ++ +++F + S KDGK + +I FK+E +A+K +
Sbjct: 395 LLAKNLPYKVTQDELKEVFEDAAEIRLVS----KDGKSKGIAYIEFKTEADAEKTFEEKQ 450
Query: 64 KSFIDTSRITVEFCKSFGD-----PAKPRAWSKHAQK--PSQPKQPPKDSTTPEIKKDEK 116
+ ID I++ + G K WS ++ S + T E+ +
Sbjct: 451 GTEIDGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSYSATEETLQEVFEKAT 510
Query: 117 KKKVAGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDS 176
KV + F EF S + + ++ + + + N S
Sbjct: 511 FIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIEGRAIRLELQGPRGSPNARSQP 570
Query: 177 GQESEEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSE-----EEESED 231
+ +G ED EE E S +++++V + SS+ + SE+
Sbjct: 571 SKTLFVKGLSEDTTEETLKE---------SFDGSVRARIVTDRETGSSKGFGFVDFNSEE 621
Query: 232 EAVHCDEGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGK 271
+A E E E D + L KG G G G+
Sbjct: 622 DAKAAKEAMEDGEIDGNKV-TLDWAKPKGEGGFGGRGGGR 660
Score = 32.3 bits (72), Expect = 2.2
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 670 KKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEEEEEESLP 728
K L TP + PA+ +G+ + E+ EE D+S E++E+E+E+E+E P
Sbjct: 116 KALVATPGKKGAAIPAKG--AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEP 172
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 80.1 bits (196), Expect = 9e-15
Identities = 97/442 (21%), Positives = 179/442 (40%), Gaps = 77/442 (17%)
Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
L+V +L TE L + FS GP+ + D +T++ G+A++ F P A +A +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
+ V +G+ + ++ S +++ S S +G+ K ++ D N A ++T N
Sbjct: 73 NFDVIKGKPVRIMWS--QRDPSLRKSGVGNIFIKNLDKSID--NKAL---YDTFSAFGNI 125
Query: 524 VADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAE 583
++ + N +K F H A R ++ R+ + S
Sbjct: 126 LSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGA 185
Query: 584 RSK--TVILVKNLPAGTLAAQLQETFGHFGSL--GRVLLPEGGIT---AIVEFLEPLEAR 636
R+K T + +KN +L++ FG FG +V+ E G + V F +A+
Sbjct: 186 RAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQ 245
Query: 637 KAFRHLAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETP 696
KA + + + +Y+ A V T ++K
Sbjct: 246 KAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKF------------------------- 280
Query: 697 EDENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTV 756
E+ +++ G L++KNL+ +E+L++ FS GT+
Sbjct: 281 --------------------EQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTI 320
Query: 757 KSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPA 816
S + + + S GFGFV + PE+A KA+ ++ G +V ATKP
Sbjct: 321 TSAKVMMEGGR-----SKGFGFVCFSSPEEATKAVTEMNGRIV------------ATKPL 363
Query: 817 -VTLARKKQVPRKQTTSKILVR 837
V LA++K+ + T++ + R
Sbjct: 364 YVALAQRKEERQAHLTNQYMQR 385
Score = 76.3 bits (186), Expect = 1e-13
Identities = 52/180 (28%), Positives = 91/180 (50%), Gaps = 12/180 (6%)
Query: 716 EEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMG 775
+E E E + ++IKN D +E+LK++F K G S + ++ S G
Sbjct: 177 KEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGK----SKG 232
Query: 776 FGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARK-KQVPRKQTTS-- 832
FGFV + + E AQKA+ ++ G ++G ++ V +++ + L RK +Q+ + + T
Sbjct: 233 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQ 292
Query: 833 --KILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
+ V+N+ +R+ FS FG T+ K M G +GFGFV F + ++A +A
Sbjct: 293 GVNLYVKNLDDGIDDERLRKEFSPFG---TITSAKVMMEGGRSKGFGFVCFSSPEEATKA 349
Score = 75.5 bits (184), Expect = 2e-13
Identities = 55/194 (28%), Positives = 100/194 (51%), Gaps = 18/194 (9%)
Query: 732 LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKAL 791
+FIKNL+ + L + FS G + SC + +N S G+GFV + E A++A+
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-----SKGYGFVHFETQEAAERAI 155
Query: 792 KQLQGHVVDGHKLEV-RISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
+++ G +++ K+ V R R + A AR K+ + + ++N +++
Sbjct: 156 EKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEF------TNVYIKNFGEDMDDERLKD 209
Query: 851 LFSTFGELKTVRLPKKMTG-TGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEW 909
LF FG +V++ MT +G +GFGFV F +DA++A + + + L G+++ +
Sbjct: 210 LFGKFGPALSVKV---MTDESGKSKGFGFVSFERHEDAQKAVDEM-NGKELNGKQIYVGR 265
Query: 910 ADSEVTLQA-LRRK 922
A +V Q L+RK
Sbjct: 266 AQKKVERQTELKRK 279
Score = 65.5 bits (158), Expect = 2e-10
Identities = 43/169 (25%), Positives = 84/169 (49%), Gaps = 17/169 (10%)
Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
S P +L++ +L+ D TE L E FS G + S + + S+G+ +V +++P
Sbjct: 7 SYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRR---SLGYAYVNFQQPA 63
Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
A++AL + V+ G + + S+R P++ RK I ++N+ +
Sbjct: 64 DAERALDTMNFDVIKGKPVRIMWSQR--DPSL---------RKSGVGNIFIKNLDKSIDN 112
Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
+ + + FS FG + + ++ G+ +G+GFV F T++ A+RA +
Sbjct: 113 KALYDTFSAFGNILSCKVVCDENGS---KGYGFVHFETQEAAERAIEKM 158
Score = 60.1 bits (144), Expect = 1e-08
Identities = 51/207 (24%), Positives = 98/207 (47%), Gaps = 16/207 (7%)
Query: 280 ETEKPANQKEPTTCHTVKLRGAPFNVTEKNVMEFLAPLKP-VAIRIVRNAHGNKTGYIFV 338
E E A KE T V ++ ++ ++ + + P ++++++ + G G+ FV
Sbjct: 180 EAELGARAKEFTN---VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFV 236
Query: 339 DFSNEEEVKQAL-KCNREYMGGRYIEVFR-EKNVPTTKGAPKNTTKSWQGRILGENEEEE 396
F E+ ++A+ + N + + G+ I V R +K V + + Q RI
Sbjct: 237 SFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRY----- 291
Query: 397 DLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHA 456
+ L+V+NL +E L K FS +G ++ ++ + KGF F+ F PE A
Sbjct: 292 ---QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEA 346
Query: 457 VKAYSEVDGQVFQGRMLHVLPSTIKKE 483
KA +E++G++ + L+V + K+E
Sbjct: 347 TKAVTEMNGRIVATKPLYVALAQRKEE 373
Score = 52.4 bits (124), Expect = 2e-06
Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
L VKNL +G+ +ER R+ F+ FGT+T + + G+ + FGF+ F S EEA KA N
Sbjct: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKV-MMEGGRSKGFGFVCFSSPEEATKAVTEMN 354
Query: 64 KSFIDTSRITV 74
+ T + V
Sbjct: 355 GRIVATKPLYV 365
Score = 47.8 bits (112), Expect = 5e-05
Identities = 23/73 (31%), Positives = 37/73 (50%)
Query: 2 SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
+ + +KN M +ER + LF FG + + GK + FGF+ F+ E+AQKA
Sbjct: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDE 250
Query: 62 FNKSFIDTSRITV 74
N ++ +I V
Sbjct: 251 MNGKELNGKQIYV 263
Score = 43.9 bits (102), Expect = 7e-04
Identities = 85/377 (22%), Positives = 147/377 (38%), Gaps = 52/377 (13%)
Query: 304 NVTEKNVMEFLAPLKPV-AIRIVRNAHGNKT-GYIFVDFSNEEEVKQALKCNREYMGGRY 361
+VTE + E +P P+ +IR+ R+ ++ GY +V+F + ++AL
Sbjct: 21 DVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT--------- 71
Query: 362 IEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESG--RLFVRNLPYTSTEEDLE 419
N KG P S + + L +SG +F++NL + + L
Sbjct: 72 ------MNFDVIKGKPVRIMWS---------QRDPSLRKSGVGNIFIKNLDKSIDNKALY 116
Query: 420 KLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV--LP 477
FS +G + D KG+ F+ F E A +A +++G + R + V
Sbjct: 117 DTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFK 174
Query: 478 STIKKEASEDASALGSSSYKKKKEAQD-----------KANSASSHNWNTLFMGPNAVAD 526
S ++EA A A ++ K +D K A S T G +
Sbjct: 175 SRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFG 234
Query: 527 AIA-QKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERS 585
++ +++ + V + K ++ +G Q E + L + Q R
Sbjct: 235 FVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL---KRKFEQMKQDRITRY 291
Query: 586 KTV-ILVKNLPAGTLAAQLQETFGHFGSL-GRVLLPEGGIT---AIVEFLEPLEARKAFR 640
+ V + VKNL G +L++ F FG++ ++ EGG + V F P EA KA
Sbjct: 292 QGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVT 351
Query: 641 HLAYSKFHHVPLYLEWA 657
+ PLY+ A
Sbjct: 352 EMNGRIVATKPLYVALA 368
Score = 40.8 bits (94), Expect = 0.006
Identities = 19/79 (24%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
+ + +KNL + + F+AFG + C + ++G + +GF+ F+++E A++A +
Sbjct: 98 VGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYGFVHFETQEAAERAIE 156
Query: 61 HFNKSFIDTSRITVEFCKS 79
N ++ ++ V KS
Sbjct: 157 KMNGMLLNDRKVFVGRFKS 175
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 77.8 bits (190), Expect = 5e-14
Identities = 54/194 (27%), Positives = 99/194 (51%), Gaps = 17/194 (8%)
Query: 732 LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKAL 791
+F+KNL+ + L + S G + SC++ +N S G+GFV + E A++A+
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENG-----SKGYGFVHFETHEAAERAI 155
Query: 792 KQLQGHVVDGHKLEV-RISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
K++ G +++G K+ V + R + A AR K+ P + ++N +++
Sbjct: 156 KKMNGMLLNGRKVFVGQFKSRKEREAELGARAKEFP------NVYIKNFGEDMDDERLKD 209
Query: 851 LFSTFGELKTVRLPKKMTG-TGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRLVLEW 909
LF FG +V K MT +G +GFGFV F +DA++A + + + L G+++ +
Sbjct: 210 LFGKFGPALSV---KVMTDESGKSKGFGFVSFERHEDAQKAVDEM-NGKELNGKQIYVGR 265
Query: 910 ADSEVTLQALRRKT 923
A +V Q ++T
Sbjct: 266 AQKKVERQTELKRT 279
Score = 76.3 bits (186), Expect = 1e-13
Identities = 56/183 (30%), Positives = 92/183 (50%), Gaps = 16/183 (8%)
Query: 714 EEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLS 773
+E E E + P ++IKN D +E+LK++F K G S + ++ S
Sbjct: 177 KEREAELGARAKEFPN--VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGK----S 230
Query: 774 MGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEV----RISERATKPAVTLARKKQ--VPR 827
GFGFV + + E AQKA+ ++ G ++G ++ V + ER T+ T + KQ + R
Sbjct: 231 KGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITR 290
Query: 828 KQTTSKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDA 887
Q + + V+N+ +R+ FS FG T+ K M G +GFGFV F + ++A
Sbjct: 291 YQVVN-LYVKNLDDGIDDERLRKAFSPFG---TITSAKVMMEGGRSKGFGFVCFSSPEEA 346
Query: 888 KRA 890
+A
Sbjct: 347 TKA 349
Score = 68.2 bits (165), Expect = 4e-11
Identities = 96/443 (21%), Positives = 176/443 (39%), Gaps = 79/443 (17%)
Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
L+V +L TE L + FS GP+ + D +T +A++ F + A A +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72
Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKK-KKEAQDKANSASSHNWNTLFMGPN 522
+ V +G+ + ++ S +++ S S +G+ K K +KA ++T+ N
Sbjct: 73 NFDVIKGKPVRIMWS--QRDPSLRKSGVGNIFVKNLDKSINNKAL------YDTVSAFGN 124
Query: 523 AVADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAA 582
++ + N +K F H A R ++ R+ + S
Sbjct: 125 ILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELG 184
Query: 583 ERSKTV--ILVKNLPAGTLAAQLQETFGHFGSL--GRVLLPEGGIT---AIVEFLEPLEA 635
R+K + +KN +L++ FG FG +V+ E G + V F +A
Sbjct: 185 ARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDA 244
Query: 636 RKAFRHLAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGET 695
+KA + + + +Y VG ++ +L+ T E M++D V +
Sbjct: 245 QKAVDEMNGKELNGKQIY-----VGRAQKKVERQTELKRT-FEQMKQDRITRYQVVN--- 295
Query: 696 PEDENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGT 755
L++KNL+ +E+L++ FS GT
Sbjct: 296 ------------------------------------LYVKNLDDGIDDERLRKAFSPFGT 319
Query: 756 VKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKP 815
+ S + + + S GFGFV + PE+A KA+ ++ G +V ATKP
Sbjct: 320 ITSAKVMMEGGR-----SKGFGFVCFSSPEEATKAVTEMNGRIV------------ATKP 362
Query: 816 A-VTLARKKQVPRKQTTSKILVR 837
V LA++K+ + T++ + R
Sbjct: 363 LYVALAQRKEERQAYLTNEYMQR 385
Score = 59.3 bits (142), Expect = 2e-08
Identities = 46/180 (25%), Positives = 86/180 (47%), Gaps = 18/180 (10%)
Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
S P +L++ +L+ D TE L E FS G + S I + +G S + +V ++ +
Sbjct: 7 SYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSG---SSNYAYVNFQHTK 63
Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
A+ AL + V+ G + + S+R P++ RK I V+N+ ++
Sbjct: 64 DAEHALDTMNFDVIKGKPVRIMWSQR--DPSL---------RKSGVGNIFVKNLDKSINN 112
Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLYGRRL 905
+ + + S FG + + + G+ +G+GFV F T + A+RA + + L GR++
Sbjct: 113 KALYDTVSAFGNILSCNVVCDENGS---KGYGFVHFETHEAAERAIKKM-NGMLLNGRKV 168
Score = 58.9 bits (141), Expect = 2e-08
Identities = 40/165 (24%), Positives = 82/165 (49%), Gaps = 10/165 (6%)
Query: 320 VAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL-KCNREYMGGRYIEVFREKNVPTTKGAPK 378
++++++ + G G+ FV F E+ ++A+ + N + + G+ I V R + + K
Sbjct: 218 LSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELK 277
Query: 379 NTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSL 438
T + + ++ + L+V+NL +E L K FS +G ++ ++
Sbjct: 278 RTFEQMK-------QDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEG- 329
Query: 439 TKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKKE 483
+ KGF F+ F PE A KA +E++G++ + L+V + K+E
Sbjct: 330 -GRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEE 373
Score = 55.1 bits (131), Expect = 3e-07
Identities = 42/160 (26%), Positives = 71/160 (44%), Gaps = 26/160 (16%)
Query: 320 VAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTTKGAPKN 379
++ +V + +G+K GY FV F E ++A+K G N
Sbjct: 126 LSCNVVCDENGSK-GYGFVHFETHEAAERAIK--------------------KMNGMLLN 164
Query: 380 TTKSWQGRILGENEEEEDLA----ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPI 435
K + G+ E E +L E ++++N +E L+ LF K+GP +
Sbjct: 165 GRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMT 224
Query: 436 DSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
D + K KGF F++F E A KA E++G+ G+ ++V
Sbjct: 225 DE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263
Score = 53.1 bits (126), Expect = 1e-06
Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
L VKNL +G+ +ER R+ F+ FGT+T + + G+ + FGF+ F S EEA KA N
Sbjct: 296 LYVKNLDDGIDDERLRKAFSPFGTITSAKV-MMEGGRSKGFGFVCFSSPEEATKAVTEMN 354
Query: 64 KSFIDTSRITV 74
+ T + V
Sbjct: 355 GRIVATKPLYV 365
Score = 47.4 bits (111), Expect = 7e-05
Identities = 23/69 (33%), Positives = 35/69 (50%)
Query: 6 VKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFNKS 65
+KN M +ER + LF FG + + GK + FGF+ F+ E+AQKA N
Sbjct: 195 IKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGK 254
Query: 66 FIDTSRITV 74
++ +I V
Sbjct: 255 ELNGKQIYV 263
Score = 45.8 bits (107), Expect = 2e-04
Identities = 83/377 (22%), Positives = 145/377 (38%), Gaps = 52/377 (13%)
Query: 304 NVTEKNVMEFLAPLKPV-AIRIVRNA-HGNKTGYIFVDFSNEEEVKQALKCNREYMGGRY 361
+VTE + E +P P+ +IRI R+ + Y +V+F + ++ + AL
Sbjct: 21 DVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDT--------- 71
Query: 362 IEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESG--RLFVRNLPYTSTEEDLE 419
N KG P S + + L +SG +FV+NL + + L
Sbjct: 72 ------MNFDVIKGKPVRIMWS---------QRDPSLRKSGVGNIFVKNLDKSINNKALY 116
Query: 420 KLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPST 479
S +G + + D KG+ F+ F E A +A +++G + GR + V
Sbjct: 117 DTVSAFGNILSCNVVCDE--NGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFK 174
Query: 480 IKKEASEDASALGSS-------------SYKKKKEAQDKANSASSHNWNTLFMGPNAVAD 526
+KE + A ++ K+ K A S T G +
Sbjct: 175 SRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFG 234
Query: 527 AIA-QKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERS 585
++ +++ + V + K ++ +G Q E + L + + Q R
Sbjct: 235 FVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTEL---KRTFEQMKQDRITRY 291
Query: 586 KTV-ILVKNLPAGTLAAQLQETFGHFGSL-GRVLLPEGGIT---AIVEFLEPLEARKAFR 640
+ V + VKNL G +L++ F FG++ ++ EGG + V F P EA KA
Sbjct: 292 QVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVT 351
Query: 641 HLAYSKFHHVPLYLEWA 657
+ PLY+ A
Sbjct: 352 EMNGRIVATKPLYVALA 368
Score = 39.7 bits (91), Expect = 0.014
Identities = 20/79 (25%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
+ + VKNL + + +AFG + C++ ++G + +GF+ F++ E A++A K
Sbjct: 98 VGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGS-KGYGFVHFETHEAAERAIK 156
Query: 61 HFNKSFIDTSRITVEFCKS 79
N ++ ++ V KS
Sbjct: 157 KMNGMLLNGRKVFVGQFKS 175
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 77.8 bits (190), Expect = 5e-14
Identities = 52/184 (28%), Positives = 95/184 (51%), Gaps = 12/184 (6%)
Query: 716 EEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMG 775
++ E E ++ ++IKN D +E+LK+VFSK G K+ S+ + +G S G
Sbjct: 176 KDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG--KTLSVKVMTDSSG--KSKG 231
Query: 776 FGFVEYRKPEQAQKALKQLQGHVVDGHKLEV-RISERATKPAVTLARKKQVPRKQTTS-- 832
FGFV + E A+KA++++ G ++G + V R ++ + A +Q+ R++
Sbjct: 232 FGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQ 291
Query: 833 --KILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
K+ ++N+ ++R FS+FG + V K M G +GFG + F + +DA +A
Sbjct: 292 GVKLYIKNLDDTIDDEKLRNEFSSFGSISRV---KVMQEEGQSKGFGLICFSSPEDATKA 348
Query: 891 FNAL 894
+
Sbjct: 349 MTEM 352
Score = 57.8 bits (138), Expect = 5e-08
Identities = 41/161 (25%), Positives = 80/161 (49%), Gaps = 14/161 (8%)
Query: 318 KPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK-CNREYMGGRYIEVFREKNVPTTKGA 376
K ++++++ ++ G G+ FV F + E K+A++ N + G+ I V R A
Sbjct: 215 KTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGR---------A 265
Query: 377 PKNTTKSWQGRILGENEEEEDL--AESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYP 434
K + + + + E + E + + +L+++NL T +E L FS +G +S +
Sbjct: 266 QKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVM 325
Query: 435 IDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
+ + KGF I F PE A KA +E++G++ + L +
Sbjct: 326 QEE--GQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSI 364
Score = 56.2 bits (134), Expect = 1e-07
Identities = 49/177 (27%), Positives = 85/177 (48%), Gaps = 27/177 (15%)
Query: 304 NVTEKNVME-FLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYI 362
++ K + E F A K ++ +++ + G+K GY FV F N+ +A+ E M G+ +
Sbjct: 108 SIDNKTLYEHFSAFGKILSSKVMSDDQGSK-GYAFVHFQNQSAADRAI----EEMNGKLL 162
Query: 363 EVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDL----AESGRLFVRNLPYTSTEEDL 418
KG K + GR + E +L +E ++++N +E L
Sbjct: 163 -----------KGC-----KVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERL 206
Query: 419 EKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV 475
+ +FSKYG + DS + K KGF F++F E A KA E++G+ G+++ V
Sbjct: 207 KDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFV 262
Score = 54.3 bits (129), Expect = 5e-07
Identities = 40/164 (24%), Positives = 75/164 (45%), Gaps = 17/164 (10%)
Query: 731 TLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKA 790
+L++ +L+ D TE+ L FS VG V S I + + S+G+ +V + + AQKA
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRR---SLGYAYVNFLQLADAQKA 67
Query: 791 LKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
L + ++ G + + S+R R+ + ++N+ ++ + E
Sbjct: 68 LDTMNFDIIKGKSIRLMWSQR-----------DAYLRRSGIGNVFIKNLDKSIDNKTLYE 116
Query: 851 LFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
FS FG++ + K M+ +G+ FV F + A RA +
Sbjct: 117 HFSAFGKILS---SKVMSDDQGSKGYAFVHFQNQSAADRAIEEM 157
Score = 53.5 bits (127), Expect = 9e-07
Identities = 27/95 (28%), Positives = 52/95 (54%), Gaps = 8/95 (8%)
Query: 720 EEEEEESLPGCT---LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGF 776
E+ + E + GC L+IKNL+ +EKL+ FS G++ + +++ + S GF
Sbjct: 280 EQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQ-----SKGF 334
Query: 777 GFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISER 811
G + + PE A KA+ ++ G ++ L + +++R
Sbjct: 335 GLICFSSPEDATKAMTEMNGRILGSKPLSIALAQR 369
Score = 43.9 bits (102), Expect = 7e-04
Identities = 22/73 (30%), Positives = 36/73 (49%)
Query: 2 SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
+ + +KN M +ER + +F+ +G + GK + FGF+ F S E A+KA +
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEE 249
Query: 62 FNKSFIDTSRITV 74
N I+ I V
Sbjct: 250 MNGRDINGQLIFV 262
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/72 (27%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Query: 3 RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHF 62
+L +KNL + + +E+ R F++FG+++ + ++G+ + FG I F S E+A KA
Sbjct: 294 KLYIKNLDDTIDDEKLRNEFSSFGSISRVKV-MQEEGQSKGFGLICFSSPEDATKAMTEM 352
Query: 63 NKSFIDTSRITV 74
N + + +++
Sbjct: 353 NGRILGSKPLSI 364
Score = 39.7 bits (91), Expect = 0.014
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 25/218 (11%)
Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
L+V +L TE+ L + FS GP+ + D +T++ G+A++ F+ A KA +
Sbjct: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71
Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
+ + +G+ + ++ S +++A S +G+ K ++ D TL+ +A
Sbjct: 72 NFDIIKGKSIRLMWS--QRDAYLRRSGIGNVFIKNLDKSIDN---------KTLYEHFSA 120
Query: 524 VADAIAQKY----NATKSQVFDHETKGSVAVRVALGET--QLVQEVRRFLIDNGVSLDSF 577
++ K +K F H S A R A+ E +L++ + F+ G +
Sbjct: 121 FGKILSSKVMSDDQGSKGYAFVHFQNQSAADR-AIEEMNGKLLKGCKVFV---GRFKNRK 176
Query: 578 SQAAAERSK----TVILVKNLPAGTLAAQLQETFGHFG 611
+ A RSK T + +KN +L++ F +G
Sbjct: 177 DREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
>gi|55956921 heterogeneous nuclear ribonucleoprotein A/B isoform b
[Homo sapiens]
Length = 285
Score = 77.4 bits (189), Expect = 6e-14
Identities = 62/232 (26%), Positives = 102/232 (43%), Gaps = 33/232 (14%)
Query: 678 EPMEKDPAEP---ETVPDGETPEDENP-TEEGADNSSAK--------MEEEEEEEEEEEE 725
+PME A E VP+GE+P GA ++A E ++ + EE
Sbjct: 8 QPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEE 67
Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
+F+ L++DT+++ LK+ F+K G V C+I N S GFGF+ ++
Sbjct: 68 DAG--KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGR---SRGFGFILFKDAA 122
Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
+K L Q + H+L+ R+ + +K +K KI V + +A
Sbjct: 123 SVEKVLDQKE------HRLDGRVID---------PKKAMAMKKDPVKKIFVGGLNPEATE 167
Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHS 897
+IRE F FGE++ + LP RGF F+ F ++ K+ H+
Sbjct: 168 EKIREYFGEFGEIEAIELPMD-PKLNKRRGFVFITFKEEEPVKKVLEKKFHT 218
Score = 47.8 bits (112), Expect = 5e-05
Identities = 49/227 (21%), Positives = 83/227 (36%), Gaps = 33/227 (14%)
Query: 238 EGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEAR---AETEKPANQKEPTTCH 294
E + A E A P + G G G PP AE ++ K
Sbjct: 11 ETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAG 70
Query: 295 TVKLRGAPFNVTEKNVMEFLAPLKPVA---IRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
+ + G ++ ++K++ ++ V I++ N G G+ F+ F + V++ L
Sbjct: 71 KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNT-GRSRGFGFILFKDAASVEKVLD 129
Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
+ GR I+ K K P ++FV L
Sbjct: 130 QKEHRLDGRVID---PKKAMAMKKDPVK-----------------------KIFVGGLNP 163
Query: 412 TSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVK 458
+TEE + + F ++G + + P+D K +GF FITF E K
Sbjct: 164 EATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKK 210
Score = 33.1 bits (74), Expect = 1.3
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 3 RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKD-GKFRKFGFIGFKSEEEAQK 57
++ V L ++ + F FG + DC++K + G+ R FGFI FK +K
Sbjct: 71 KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEK 126
>gi|55956919 heterogeneous nuclear ribonucleoprotein A/B isoform a
[Homo sapiens]
Length = 332
Score = 77.4 bits (189), Expect = 6e-14
Identities = 62/232 (26%), Positives = 102/232 (43%), Gaps = 33/232 (14%)
Query: 678 EPMEKDPAEP---ETVPDGETPEDENP-TEEGADNSSAK--------MEEEEEEEEEEEE 725
+PME A E VP+GE+P GA ++A E ++ + EE
Sbjct: 8 QPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEE 67
Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
+F+ L++DT+++ LK+ F+K G V C+I N S GFGF+ ++
Sbjct: 68 DAG--KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGR---SRGFGFILFKDAA 122
Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHS 845
+K L Q + H+L+ R+ + +K +K KI V + +A
Sbjct: 123 SVEKVLDQKE------HRLDGRVID---------PKKAMAMKKDPVKKIFVGGLNPEATE 167
Query: 846 REIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHS 897
+IRE F FGE++ + LP RGF F+ F ++ K+ H+
Sbjct: 168 EKIREYFGEFGEIEAIELPMD-PKLNKRRGFVFITFKEEEPVKKVLEKKFHT 218
Score = 50.4 bits (119), Expect = 8e-06
Identities = 57/287 (19%), Positives = 100/287 (34%), Gaps = 37/287 (12%)
Query: 238 EGSEAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEAR---AETEKPANQKEPTTCH 294
E + A E A P + G G G PP AE ++ K
Sbjct: 11 ETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAG 70
Query: 295 TVKLRGAPFNVTEKNVMEFLAPLKPVA---IRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
+ + G ++ ++K++ ++ V I++ N G G+ F+ F + V++ L
Sbjct: 71 KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNT-GRSRGFGFILFKDAASVEKVLD 129
Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
+ GR I+ K K P ++FV L
Sbjct: 130 QKEHRLDGRVID---PKKAMAMKKDPVK-----------------------KIFVGGLNP 163
Query: 412 TSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGR 471
+TEE + + F ++G + + P+D K +GF FITF E VK E G
Sbjct: 164 EATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFK-EEEPVKKVLEKKFHTVSGS 222
Query: 472 MLHV---LPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWN 515
+ P + ++ + G+ + + S +WN
Sbjct: 223 KCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWN 269
Score = 33.1 bits (74), Expect = 1.3
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 3 RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKD-GKFRKFGFIGFKSEEEAQK 57
++ V L ++ + F FG + DC++K + G+ R FGFI FK +K
Sbjct: 71 KMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEK 126
>gi|7661952 squamous cell carcinoma antigen recognized by T cells 3
[Homo sapiens]
Length = 963
Score = 75.5 bits (184), Expect = 2e-13
Identities = 80/316 (25%), Positives = 136/316 (43%), Gaps = 57/316 (18%)
Query: 190 EEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEEDSSA 249
E+EA+L + + E + K +K E+ DE + G + EE+ S
Sbjct: 585 EKEAALVQQEEEKAEQRKRARAEKKALKKKKKIRGPEKRGADEDDEKEWGDDEEEQPSKR 644
Query: 250 TPVLQERDSKGAGQEQGM-----PAGKKRPPEARAETEKPANQKE---------PTTCH- 294
V E AG+ Q + PAGK A + E P+ QKE P H
Sbjct: 645 RRV--ENSIPAAGETQNVEVAAGPAGKC----AAVDVEPPSKQKEKAASLKRDMPKVLHD 698
Query: 295 ------TVKLRGAPFNVTEKNVMEFLAPL-----KPVAIRIVRNAHGNKTGYIFVDFSNE 343
TV + P+++ E + L PL + V IR + + G+ GY +V+F E
Sbjct: 699 SSKDSITVFVSNLPYSMQEPDTK--LRPLFEACGEVVQIRPIFSNRGDFRGYCYVEFKEE 756
Query: 344 EEVKQALKCNREYMGGRYIEVF----REKNVPTTKGAPKNTTKSWQGRILGENEEEEDLA 399
+ QAL+ +R+ + GR + V + KN P K +T+
Sbjct: 757 KSALQALEMDRKSVEGRPMFVSPCVDKSKN-PDFKVFRYSTS-----------------L 798
Query: 400 ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
E +LF+ LP++ T+E+LE++ +G + +L + + KPKG A++ + A +A
Sbjct: 799 EKHKLFISGLPFSCTKEELEEICKAHGTVKDLRL-VTNRAGKPKGLAYVEYENESQASQA 857
Query: 460 YSEVDGQVFQGRMLHV 475
++DG + ++ V
Sbjct: 858 VMKMDGMTIKENIIKV 873
Score = 47.8 bits (112), Expect = 5e-05
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 13/108 (12%)
Query: 726 SLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPE 785
SL LFI L F T+E+L+E+ GTVK + N+AG G +VEY
Sbjct: 797 SLEKHKLFISGLPFSCTKEELEEICKAHGTVKDLRL--VTNRAG--KPKGLAYVEYENES 852
Query: 786 QAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSK 833
QA +A+ ++ G + I E K A++ +++VP K T K
Sbjct: 853 QASQAVMKMDG---------MTIKENIIKVAISNPPQRKVPEKPETRK 891
Score = 36.2 bits (82), Expect = 0.15
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 4 LIVKNLPNGMKEE--RFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
+ V NLP M+E + R LF A G + F+ G FR + ++ FK E+ A +A +
Sbjct: 706 VFVSNLPYSMQEPDTKLRPLFEACGEVVQIRPIFSNRGDFRGYCYVEFKEEKSALQALEM 765
Query: 62 FNKS 65
KS
Sbjct: 766 DRKS 769
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/157 (21%), Positives = 61/157 (38%), Gaps = 19/157 (12%)
Query: 3 RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHF 62
+L + LP +E ++ A GT+ D L + GK + ++ +++E +A +A
Sbjct: 802 KLFISGLPFSCTKEELEEICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKM 861
Query: 63 NKSFIDTSRITVEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKVAG 122
+ I + I V + +P + K +KP K P P+ K +
Sbjct: 862 DGMTIKENIIKV----AISNPPQ----RKVPEKPETRKAPGGPMLLPQTYGARGKGR--- 910
Query: 123 QLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPS 159
T+ QR + AA A +G A P+
Sbjct: 911 --------TQLSLLPRALQRPSAAAPQAENGPAAAPA 939
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 73.9 bits (180), Expect = 7e-13
Identities = 88/415 (21%), Positives = 166/415 (40%), Gaps = 64/415 (15%)
Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
L+V +L TE L + FS GP+ + D T++ G+A+I F P A +A +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTM 72
Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNA 523
+ ++ +G+ + ++ S +++ S +G+ K +++ D N A ++T N
Sbjct: 73 NFEMLKGQPIRIMWS--QRDPGLRKSGVGNIFIKNLEDSID--NKALYDTFSTF---GNI 125
Query: 524 VADAIAQKYNATKSQVFDHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAE 583
++ +A + ++ F H A + ++ R+ + + S
Sbjct: 126 LSCKVACDEHGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGA 185
Query: 584 RSK--TVILVKNLPAGTLAAQLQETFGHFGSL--GRVLLPEGGIT---AIVEFLEPLEAR 636
R+ T I VKNLP LQ+ F FG + +V+ G + V F + EA+
Sbjct: 186 RALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQ 245
Query: 637 KAFRHLAYSKFHHVPLYLEWAPVGVFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETP 696
KA H+ + LY A
Sbjct: 246 KAVVHMNGKEVSGRLLYAGRA--------------------------------------- 266
Query: 697 EDENPTEEGADNSSAKMEEEEEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTV 756
++ + + E+ +++ G L++KNL+ ++KL++ FS G +
Sbjct: 267 ------QKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVI 320
Query: 757 KSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISER 811
S + + S GFGFV + PE+A KA+ ++ G +V L V +++R
Sbjct: 321 TSAKVMTEGGH-----SKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQR 370
Score = 72.4 bits (176), Expect = 2e-12
Identities = 53/179 (29%), Positives = 90/179 (50%), Gaps = 12/179 (6%)
Query: 717 EEEEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGF 776
E E E +L +++KNL D E+ L+++FS+ G K S+ ++ +G S F
Sbjct: 178 EREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFG--KMLSVKVMRDNSGH--SRCF 233
Query: 777 GFVEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLAR-----KKQVPRKQTT 831
GFV + K E+AQKA+ + G V G L +++ + L R K+ R+
Sbjct: 234 GFVNFEKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQG 293
Query: 832 SKILVRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
+ V+N+ ++R+ FS +G + + K MT G +GFGFV F + ++A +A
Sbjct: 294 VNLYVKNLDDSIDDDKLRKEFSPYGVITSA---KVMTEGGHSKGFGFVCFSSPEEATKA 349
Score = 71.6 bits (174), Expect = 3e-12
Identities = 47/160 (29%), Positives = 84/160 (52%), Gaps = 14/160 (8%)
Query: 732 LFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQAQKAL 791
+FIKNL + L + FS G + SC ++ ++ S GFGFV + E AQ+A+
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHG-----SRGFGFVHFETHEAAQQAI 155
Query: 792 KQLQGHVVDGHKLEV-RISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSREIRE 850
+ G +++ K+ V R + A AR + + I V+N+P + +++
Sbjct: 156 NTMNGMLLNDRKVFVGHFKSRREREAELGARALEF------TNIYVKNLPVDVDEQGLQD 209
Query: 851 LFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRA 890
LFS FG++ +V++ + +G R FGFV+F ++A++A
Sbjct: 210 LFSQFGKMLSVKVMR--DNSGHSRCFGFVNFEKHEEAQKA 247
Score = 68.2 bits (165), Expect = 4e-11
Identities = 43/167 (25%), Positives = 83/167 (49%), Gaps = 17/167 (10%)
Query: 728 PGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRKPEQA 787
P +L++ +L+ D TE L E FS G + S + + S+G+ ++ +++P A
Sbjct: 9 PLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRD---VATRRSLGYAYINFQQPADA 65
Query: 788 QKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPFQAHSRE 847
++AL + ++ G + + S+R P + RK I ++N+ ++
Sbjct: 66 ERALDTMNFEMLKGQPIRIMWSQR--DPGL---------RKSGVGNIFIKNLEDSIDNKA 114
Query: 848 IRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNAL 894
+ + FSTFG + + ++ G+ RGFGFV F T + A++A N +
Sbjct: 115 LYDTFSTFGNILSCKVACDEHGS---RGFGFVHFETHEAAQQAINTM 158
Score = 60.5 bits (145), Expect = 7e-09
Identities = 46/191 (24%), Positives = 93/191 (48%), Gaps = 13/191 (6%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPL-KPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQAL-KCN 353
+ ++ P +V E+ + + + K ++++++R+ G+ + FV+F EE ++A+ N
Sbjct: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMN 252
Query: 354 REYMGGRYIEVFR-EKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYT 412
+ + GR + R +K V + + Q R+ + L+V+NL +
Sbjct: 253 GKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRY--------QGVNLYVKNLDDS 304
Query: 413 STEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRM 472
++ L K FS YG ++ + KGF F+ F PE A KA +E++G++ +
Sbjct: 305 IDDDKLRKEFSPYGVITSAKVMTEG--GHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKP 362
Query: 473 LHVLPSTIKKE 483
L+V + K+E
Sbjct: 363 LYVALAQRKEE 373
Score = 51.6 bits (122), Expect = 3e-06
Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 26/159 (16%)
Query: 320 VAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTTKGAPKN 379
++ ++ + HG++ G+ FV F E +QA+ T G N
Sbjct: 126 LSCKVACDEHGSR-GFGFVHFETHEAAQQAIN--------------------TMNGMLLN 164
Query: 380 TTKSWQGRILGENEEEEDLA----ESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPI 435
K + G E E +L E ++V+NLP E+ L+ LFS++G + +
Sbjct: 165 DRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMR 224
Query: 436 DSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLH 474
D+ + + F F+ F E A KA ++G+ GR+L+
Sbjct: 225 DN-SGHSRCFGFVNFEKHEEAQKAVVHMNGKEVSGRLLY 262
Score = 50.1 bits (118), Expect = 1e-05
Identities = 24/62 (38%), Positives = 34/62 (54%)
Query: 2 SRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKH 61
+ + VKNLP + E+ + LF+ FG + + G R FGF+ F+ EEAQKA H
Sbjct: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVH 250
Query: 62 FN 63
N
Sbjct: 251 MN 252
Score = 46.2 bits (108), Expect = 1e-04
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 1/71 (1%)
Query: 4 LIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQKHFN 63
L VKNL + + +++ R+ F+ +G +T + T+ G + FGF+ F S EEA KA N
Sbjct: 296 LYVKNLDDSIDDDKLRKEFSPYGVITSAKV-MTEGGHSKGFGFVCFSSPEEATKAVTEMN 354
Query: 64 KSFIDTSRITV 74
+ T + V
Sbjct: 355 GRIVGTKPLYV 365
Score = 42.4 bits (98), Expect = 0.002
Identities = 46/193 (23%), Positives = 83/193 (43%), Gaps = 30/193 (15%)
Query: 304 NVTEKNVMEFLAPLKPV-AIRIVRNAHGNKT-GYIFVDFSNEEEVKQALKC-NREYMGGR 360
+VTE + E +P P+ +IR+ R+ ++ GY +++F + ++AL N E + G+
Sbjct: 21 DVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEMLKGQ 80
Query: 361 YIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK 420
I + + P G K+ G +F++NL + + L
Sbjct: 81 PIRIMWSQRDP---GLRKSGV--------------------GNIFIKNLEDSIDNKALYD 117
Query: 421 LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHV--LPS 478
FS +G + D +GF F+ F E A +A + ++G + R + V S
Sbjct: 118 TFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKS 175
Query: 479 TIKKEASEDASAL 491
++EA A AL
Sbjct: 176 RREREAELGARAL 188
Score = 41.6 bits (96), Expect = 0.004
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 1 MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK 60
+ + +KNL + + + F+ FG + C + + G R FGF+ F++ E AQ+A
Sbjct: 98 VGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGS-RGFGFVHFETHEAAQQAIN 156
Query: 61 HFNKSFIDTSRITVEFCKS 79
N ++ ++ V KS
Sbjct: 157 TMNGMLLNDRKVFVGHFKS 175
>gi|74099697 heterogeneous nuclear ribonucleoprotein H2 [Homo
sapiens]
Length = 449
Score = 73.9 bits (180), Expect = 7e-13
Identities = 55/169 (32%), Positives = 83/169 (49%), Gaps = 18/169 (10%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
VK+RG P++ + VM F + K IR + G +G FV+ +EEEVK ALK
Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72
Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
+RE MG RY+EVF+ +V W + G N D A G + +R LP+
Sbjct: 73 KDRETMGHRYVEVFKSNSV----------EMDWVLKHTGPN--SPDTANDGFVRLRGLPF 120
Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
++E++ + FS + + + P+D + G AF+ F E A KA
Sbjct: 121 GCSKEEIVQFFSGLEIVPNGMTLPVD-FQGRSTGEAFVQFASQEIAEKA 168
Score = 60.1 bits (144), Expect = 1e-08
Identities = 29/88 (32%), Positives = 46/88 (52%)
Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
+ TT H V +RG P+ TE ++ F +PL P+ + I G TG V+F+ E+
Sbjct: 284 QSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVA 343
Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
A+ ++ M RY+E+F T+ GA
Sbjct: 344 AMAKDKANMQHRYVELFLNSTAGTSGGA 371
Score = 54.3 bits (129), Expect = 5e-07
Identities = 26/73 (35%), Positives = 48/73 (65%), Gaps = 2/73 (2%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
V+LRG PF +++ +++F + L+ P + + + G TG FV F+++E ++ALK +
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 354 REYMGGRYIEVFR 366
+E +G RYIE+F+
Sbjct: 173 KERIGHRYIEIFK 185
>gi|9624998 heterogeneous nuclear ribonucleoprotein H2 [Homo
sapiens]
Length = 449
Score = 73.9 bits (180), Expect = 7e-13
Identities = 55/169 (32%), Positives = 83/169 (49%), Gaps = 18/169 (10%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
VK+RG P++ + VM F + K IR + G +G FV+ +EEEVK ALK
Sbjct: 13 VKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALK 72
Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
+RE MG RY+EVF+ +V W + G N D A G + +R LP+
Sbjct: 73 KDRETMGHRYVEVFKSNSV----------EMDWVLKHTGPN--SPDTANDGFVRLRGLPF 120
Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
++E++ + FS + + + P+D + G AF+ F E A KA
Sbjct: 121 GCSKEEIVQFFSGLEIVPNGMTLPVD-FQGRSTGEAFVQFASQEIAEKA 168
Score = 60.1 bits (144), Expect = 1e-08
Identities = 29/88 (32%), Positives = 46/88 (52%)
Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
+ TT H V +RG P+ TE ++ F +PL P+ + I G TG V+F+ E+
Sbjct: 284 QSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVA 343
Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
A+ ++ M RY+E+F T+ GA
Sbjct: 344 AMAKDKANMQHRYVELFLNSTAGTSGGA 371
Score = 54.3 bits (129), Expect = 5e-07
Identities = 26/73 (35%), Positives = 48/73 (65%), Gaps = 2/73 (2%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
V+LRG PF +++ +++F + L+ P + + + G TG FV F+++E ++ALK +
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 354 REYMGGRYIEVFR 366
+E +G RYIE+F+
Sbjct: 173 KERIGHRYIEIFK 185
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 73.2 bits (178), Expect = 1e-12
Identities = 59/197 (29%), Positives = 99/197 (50%), Gaps = 33/197 (16%)
Query: 731 TLFIKNLNFDTTEEKLKEVFSKVGTVKSCS-ISKKKNKAGVLLSMGFG-----------F 778
TL++ NL+ D TE + ++FS++G KSC I+++ + V S+GF F
Sbjct: 10 TLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCF 69
Query: 779 VEYRKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSK---IL 835
VE+ + A AL + G + G +++V AT P+ +K+ TS +
Sbjct: 70 VEFYEHRDAAAALAAMNGRKILGKEVKV---NWATTPS---------SQKKDTSNHFHVF 117
Query: 836 VRNIPFQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALC 895
V ++ + + +I+ F+ FG++ R+ K M TG +G+GFV F K DA+ NA+
Sbjct: 118 VGDLSPEITTEDIKSAFAPFGKISDARVVKDM-ATGKSKGYGFVSFYNKLDAE---NAIV 173
Query: 896 H--STHLYGRRLVLEWA 910
H L GR++ WA
Sbjct: 174 HMGGQWLGGRQIRTNWA 190
Score = 53.9 bits (128), Expect = 7e-07
Identities = 47/197 (23%), Positives = 95/197 (48%), Gaps = 19/197 (9%)
Query: 284 PANQKEPTTCHTVKLRG--APFNVTEKNVMEFLAPLKPVA-IRIVRN-AHGNKTGYIFVD 339
P++QK+ T+ H G +P +T +++ AP ++ R+V++ A G GY FV
Sbjct: 103 PSSQKKDTSNHFHVFVGDLSP-EITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVS 161
Query: 340 FSNEEEVKQAL-KCNREYMGGRYIEV-FREKNVPTTKGAPKNTTKSWQGRILGENEEEED 397
F N+ + + A+ +++GGR I + + P K +N TK ++ E+ +
Sbjct: 162 FYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTK----QLRFEDVVNQS 217
Query: 398 LAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELH-YPIDSLTKKPKGFAFITFMFPEHA 456
++ ++ + T++ + + FS +G + E+ +P KG++F+ F E A
Sbjct: 218 SPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFP-------EKGYSFVRFSTHESA 270
Query: 457 VKAYSEVDGQVFQGRML 473
A V+G +G ++
Sbjct: 271 AHAIVSVNGTTIEGHVV 287
Score = 48.1 bits (113), Expect = 4e-05
Identities = 44/185 (23%), Positives = 72/185 (38%), Gaps = 24/185 (12%)
Query: 329 HGNKTGYIFVDFSNEEEVKQALKCNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRI 388
H + Y FV+F + AL M GR I K +W
Sbjct: 61 HTSNDPYCFVEFYEHRDAAAALAA----MNGRKI-------------LGKEVKVNWATT- 102
Query: 389 LGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFI 448
+ +++D + +FV +L T ED++ F+ +G +S+ D T K KG+ F+
Sbjct: 103 --PSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFV 160
Query: 449 TFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQDKANS 508
+F A A + GQ GR + +T K A + + K+ +D N
Sbjct: 161 SFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKST----QENNTKQLRFEDVVNQ 216
Query: 509 ASSHN 513
+S N
Sbjct: 217 SSPKN 221
>gi|5031753 heterogeneous nuclear ribonucleoprotein H1 [Homo
sapiens]
Length = 449
Score = 72.8 bits (177), Expect = 1e-12
Identities = 54/169 (31%), Positives = 82/169 (48%), Gaps = 18/169 (10%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
VK+RG P++ + V F + K IR + G +G FV+ +E+EVK ALK
Sbjct: 13 VKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALK 72
Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
+RE MG RY+EVF+ NV W + G N D A G + +R LP+
Sbjct: 73 KDRETMGHRYVEVFKSNNV----------EMDWVLKHTGPN--SPDTANDGFVRLRGLPF 120
Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
++E++ + FS + + + P+D + G AF+ F E A KA
Sbjct: 121 GCSKEEIVQFFSGLEIVPNGITLPVD-FQGRSTGEAFVQFASQEIAEKA 168
Score = 59.7 bits (143), Expect = 1e-08
Identities = 29/88 (32%), Positives = 45/88 (51%)
Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
+ TT H V +RG P+ TE ++ F +PL PV + I G TG V+F+ E+
Sbjct: 284 QSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVA 343
Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
A+ ++ M RY+E+F + GA
Sbjct: 344 AMSKDKANMQHRYVELFLNSTAGASGGA 371
Score = 55.5 bits (132), Expect = 2e-07
Identities = 27/73 (36%), Positives = 48/73 (65%), Gaps = 2/73 (2%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
V+LRG PF +++ +++F + L+ P I + + G TG FV F+++E ++ALK +
Sbjct: 113 VRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKH 172
Query: 354 REYMGGRYIEVFR 366
+E +G RYIE+F+
Sbjct: 173 KERIGHRYIEIFK 185
>gi|14110407 heterogeneous nuclear ribonucleoprotein D-like [Homo
sapiens]
Length = 420
Score = 72.8 bits (177), Expect = 1e-12
Identities = 57/235 (24%), Positives = 102/235 (43%), Gaps = 28/235 (11%)
Query: 662 FSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEEE 721
F S++ Q+ + + P +V + E N EE A+ S + ++++
Sbjct: 90 FKSSSIQRSAAAAAATRTARQHPPADSSVTMEDMNEYSN-IEEFAEGSKINASKNQQDDG 148
Query: 722 EEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEY 781
+ +FI L++DT+++ L E S+ G V C+I K S GFGFV +
Sbjct: 149 K---------MFIGGLSWDTSKKDLTEYLSRFGEVVDCTI---KTDPVTGRSRGFGFVLF 196
Query: 782 RKPEQAQKALKQLQGHVVDGHKLEVRISERATKPAVTLARKKQVPRKQTTSKILVRNIPF 841
+ K L +L+ H +DG ++ + R K + K+ K+ V +
Sbjct: 197 KDAASVDKVL-ELKEHKLDGKLIDPK-------------RAKALKGKEPPKKVFVGGLSP 242
Query: 842 QAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCH 896
+I+E F FGE++ + LP T T RGF F+ + ++ K+ + H
Sbjct: 243 DTSEEQIKEYFGAFGEIENIELPMD-TKTNERRGFCFITYTDEEPVKKLLESRYH 296
Score = 47.4 bits (111), Expect = 7e-05
Identities = 38/174 (21%), Positives = 73/174 (41%), Gaps = 27/174 (15%)
Query: 300 GAPFNVTEKNVMEFLAPLKPVAIRIVRN--AHGNKTGYIFVDFSNEEEVKQALKCNREYM 357
G ++ ++K++ E+L+ V ++ G G+ FV F + V + L+ +
Sbjct: 154 GLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKL 213
Query: 358 GGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEED 417
G+ I+ R K + K PK ++FV L ++EE
Sbjct: 214 DGKLIDPKRAKALKG-KEPPK------------------------KVFVGGLSPDTSEEQ 248
Query: 418 LEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGR 471
+++ F +G + + P+D+ T + +GF FIT+ E K Q+ G+
Sbjct: 249 IKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGK 302
Score = 37.0 bits (84), Expect = 0.089
Identities = 15/66 (22%), Positives = 38/66 (57%), Gaps = 3/66 (4%)
Query: 385 QGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKG 444
+G + ++ ++D G++F+ L + ++++DL + S++G + + D +T + +G
Sbjct: 134 EGSKINASKNQQD---DGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRG 190
Query: 445 FAFITF 450
F F+ F
Sbjct: 191 FGFVLF 196
Score = 31.2 bits (69), Expect = 4.9
Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 3 RLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKF-TKDGKFRKFGFIGFKSEEEAQK 57
++ V L EE+ ++ F AFG + + L TK + R F FI + EE +K
Sbjct: 234 KVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKK 289
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 72.4 bits (176), Expect = 2e-12
Identities = 52/189 (27%), Positives = 94/189 (49%), Gaps = 10/189 (5%)
Query: 724 EESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVEYRK 783
E+ +P TL++ NL+ D TE + ++FS++G K+C + + AG + + FVE+ +
Sbjct: 2 EDEMPK-TLYVGNLSRDVTEALILQLFSQIGPCKNCKMI--MDTAG---NDPYCFVEFHE 55
Query: 784 PEQAQKALKQLQGHVVDGHKLEVR--ISERATKPAVTLARKKQVPRKQTTSKILVRNIPF 841
A AL + G + G +++V + + K + + R Q + V ++
Sbjct: 56 HRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSP 115
Query: 842 QAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHLY 901
+ + +I+ F+ FG + R+ K M TG +G+GFV F K DA+ A + L
Sbjct: 116 EITTEDIKAAFAPFGRISDARVVKDM-ATGKSKGYGFVSFFNKWDAENAIQQM-GGQWLG 173
Query: 902 GRRLVLEWA 910
GR++ WA
Sbjct: 174 GRQIRTNWA 182
Score = 54.7 bits (130), Expect = 4e-07
Identities = 54/221 (24%), Positives = 99/221 (44%), Gaps = 22/221 (9%)
Query: 304 NVTEKNVMEFLAPLKPVA-IRIVRNAHGNKTGYIFVDFSNEEEVKQALKC-NREYMGGRY 361
+VTE +++ + + P +++ + GN Y FV+F AL N + G+
Sbjct: 17 DVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMNGRKIMGKE 75
Query: 362 IEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKL 421
++V N TT + K T S ++ ++ +FV +L T ED++
Sbjct: 76 VKV----NWATTPSSQKKDTSS--STVVSTQRSQDHF----HVFVGDLSPEITTEDIKAA 125
Query: 422 FSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLHVLPSTIK 481
F+ +G +S+ D T K KG+ F++F A A ++ GQ GR + +T K
Sbjct: 126 FAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 185
Query: 482 KEASEDASALGSSSYKK--KKEAQDKANSASSHNWNTLFMG 520
A + S+Y+ K+ + D+ + SS + T++ G
Sbjct: 186 PPAPK-------STYESNTKQLSYDEVVNQSSPSNCTVYCG 219
Score = 50.1 bits (118), Expect = 1e-05
Identities = 41/172 (23%), Positives = 81/172 (47%), Gaps = 12/172 (6%)
Query: 305 VTEKNVMEFLAPLKPVA-IRIVRN-AHGNKTGYIFVDFSNEEEVKQALK-CNREYMGGRY 361
+T +++ AP ++ R+V++ A G GY FV F N+ + + A++ +++GGR
Sbjct: 117 ITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQ 176
Query: 362 IEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEKL 421
I P APK+T +S ++ + + + ++ + TE+ + +
Sbjct: 177 IRTNWATRKPP---APKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQT 233
Query: 422 FSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRML 473
FS +G + E+ D KG++F+ F E A A V+G +G ++
Sbjct: 234 FSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVV 279
Score = 38.5 bits (88), Expect = 0.030
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Query: 404 LFVRNLPYTSTEEDLEKLFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEV 463
L+V NL TE + +LFS+ GP +D+ P + F+ F HA A + +
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP--YCFVEFHEHRHAAAALAAM 66
Query: 464 DGQVFQGRMLHVLPSTIKKEASEDASALGSSSYKKKKEAQD 504
+G+ G+ + V +T +D S SS+ + +QD
Sbjct: 67 NGRKIMGKEVKVNWATTPSSQKKDTS---SSTVVSTQRSQD 104
Score = 37.4 bits (85), Expect = 0.068
Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 9/84 (10%)
Query: 719 EEEEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGF 778
+E + S CT++ + TE+ +++ FS G + + K G+ F
Sbjct: 203 DEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK---------GYSF 253
Query: 779 VEYRKPEQAQKALKQLQGHVVDGH 802
V + E A A+ + G ++GH
Sbjct: 254 VRFNSHESAAHAIVSVNGTTIEGH 277
>gi|148470406 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 71.6 bits (174), Expect = 3e-12
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 18/169 (10%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
VKLRG P++ + ++V FL+ + + G ++G FV+ +E++VK ALK
Sbjct: 13 VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72
Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
+RE MG RYIEVF+ T W + G N D A G + +R LP+
Sbjct: 73 KDRESMGHRYIEVFKS----------HRTEMDWVLKHSGPN--SADSANDGFVRLRGLPF 120
Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
T+E++ + FS + + + P+D K G AF+ F E A KA
Sbjct: 121 GCTKEEIVQFFSGLEIVPNGITLPVDP-EGKITGEAFVQFASQELAEKA 168
Score = 63.2 bits (152), Expect = 1e-09
Identities = 32/88 (36%), Positives = 45/88 (51%)
Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
+ TT H V +RG P+ TE ++ F +PL PV + I G TG V+F+ EE
Sbjct: 284 QSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVA 343
Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
A+ +R M RYIE+F + GA
Sbjct: 344 AMSKDRANMQHRYIELFLNSTTGASNGA 371
Score = 53.9 bits (128), Expect = 7e-07
Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
V+LRG PF T++ +++F + L+ P I + + G TG FV F+++E ++AL +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 354 REYMGGRYIEVFR 366
+E +G RYIEVF+
Sbjct: 173 KERIGHRYIEVFK 185
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 6 VKNLPNGMKEERFRQLFAAFGTLTD-CSLKFTKDGKFRKFGFIGFKSEEEAQKA----QK 60
++ LP G +E Q F+ + + +L +GK F+ F S+E A+KA ++
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174
Query: 61 HFNKSFIDTSRITVEFCKSFGDP 83
+I+ + + E +S+ DP
Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDP 197
>gi|148470404 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 71.6 bits (174), Expect = 3e-12
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 18/169 (10%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
VKLRG P++ + ++V FL+ + + G ++G FV+ +E++VK ALK
Sbjct: 13 VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72
Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
+RE MG RYIEVF+ T W + G N D A G + +R LP+
Sbjct: 73 KDRESMGHRYIEVFKS----------HRTEMDWVLKHSGPN--SADSANDGFVRLRGLPF 120
Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
T+E++ + FS + + + P+D K G AF+ F E A KA
Sbjct: 121 GCTKEEIVQFFSGLEIVPNGITLPVDP-EGKITGEAFVQFASQELAEKA 168
Score = 63.2 bits (152), Expect = 1e-09
Identities = 32/88 (36%), Positives = 45/88 (51%)
Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
+ TT H V +RG P+ TE ++ F +PL PV + I G TG V+F+ EE
Sbjct: 284 QSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVA 343
Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
A+ +R M RYIE+F + GA
Sbjct: 344 AMSKDRANMQHRYIELFLNSTTGASNGA 371
Score = 53.9 bits (128), Expect = 7e-07
Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
V+LRG PF T++ +++F + L+ P I + + G TG FV F+++E ++AL +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 354 REYMGGRYIEVFR 366
+E +G RYIEVF+
Sbjct: 173 KERIGHRYIEVFK 185
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 6 VKNLPNGMKEERFRQLFAAFGTLTD-CSLKFTKDGKFRKFGFIGFKSEEEAQKA----QK 60
++ LP G +E Q F+ + + +L +GK F+ F S+E A+KA ++
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174
Query: 61 HFNKSFIDTSRITVEFCKSFGDP 83
+I+ + + E +S+ DP
Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDP 197
>gi|148470402 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 71.6 bits (174), Expect = 3e-12
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 18/169 (10%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
VKLRG P++ + ++V FL+ + + G ++G FV+ +E++VK ALK
Sbjct: 13 VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72
Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
+RE MG RYIEVF+ T W + G N D A G + +R LP+
Sbjct: 73 KDRESMGHRYIEVFKS----------HRTEMDWVLKHSGPN--SADSANDGFVRLRGLPF 120
Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
T+E++ + FS + + + P+D K G AF+ F E A KA
Sbjct: 121 GCTKEEIVQFFSGLEIVPNGITLPVDP-EGKITGEAFVQFASQELAEKA 168
Score = 63.2 bits (152), Expect = 1e-09
Identities = 32/88 (36%), Positives = 45/88 (51%)
Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
+ TT H V +RG P+ TE ++ F +PL PV + I G TG V+F+ EE
Sbjct: 284 QSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVA 343
Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
A+ +R M RYIE+F + GA
Sbjct: 344 AMSKDRANMQHRYIELFLNSTTGASNGA 371
Score = 53.9 bits (128), Expect = 7e-07
Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
V+LRG PF T++ +++F + L+ P I + + G TG FV F+++E ++AL +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 354 REYMGGRYIEVFR 366
+E +G RYIEVF+
Sbjct: 173 KERIGHRYIEVFK 185
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 6 VKNLPNGMKEERFRQLFAAFGTLTD-CSLKFTKDGKFRKFGFIGFKSEEEAQKA----QK 60
++ LP G +E Q F+ + + +L +GK F+ F S+E A+KA ++
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174
Query: 61 HFNKSFIDTSRITVEFCKSFGDP 83
+I+ + + E +S+ DP
Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDP 197
>gi|148470400 heterogeneous nuclear ribonucleoprotein F [Homo
sapiens]
Length = 415
Score = 71.6 bits (174), Expect = 3e-12
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 18/169 (10%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK----PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALK 351
VKLRG P++ + ++V FL+ + + G ++G FV+ +E++VK ALK
Sbjct: 13 VKLRGLPWSCSVEDVQNFLSDCTIHDGAAGVHFIYTREGRQSGEAFVELGSEDDVKMALK 72
Query: 352 CNREYMGGRYIEVFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPY 411
+RE MG RYIEVF+ T W + G N D A G + +R LP+
Sbjct: 73 KDRESMGHRYIEVFKS----------HRTEMDWVLKHSGPN--SADSANDGFVRLRGLPF 120
Query: 412 TSTEEDLEKLFSKYGPL-SELHYPIDSLTKKPKGFAFITFMFPEHAVKA 459
T+E++ + FS + + + P+D K G AF+ F E A KA
Sbjct: 121 GCTKEEIVQFFSGLEIVPNGITLPVDP-EGKITGEAFVQFASQELAEKA 168
Score = 63.2 bits (152), Expect = 1e-09
Identities = 32/88 (36%), Positives = 45/88 (51%)
Query: 289 EPTTCHTVKLRGAPFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQ 348
+ TT H V +RG P+ TE ++ F +PL PV + I G TG V+F+ EE
Sbjct: 284 QSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEEAVA 343
Query: 349 ALKCNREYMGGRYIEVFREKNVPTTKGA 376
A+ +R M RYIE+F + GA
Sbjct: 344 AMSKDRANMQHRYIELFLNSTTGASNGA 371
Score = 53.9 bits (128), Expect = 7e-07
Identities = 28/73 (38%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 296 VKLRGAPFNVTEKNVMEFLAPLK--PVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCN 353
V+LRG PF T++ +++F + L+ P I + + G TG FV F+++E ++AL +
Sbjct: 113 VRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKH 172
Query: 354 REYMGGRYIEVFR 366
+E +G RYIEVF+
Sbjct: 173 KERIGHRYIEVFK 185
Score = 32.3 bits (72), Expect = 2.2
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 6 VKNLPNGMKEERFRQLFAAFGTLTD-CSLKFTKDGKFRKFGFIGFKSEEEAQKA----QK 60
++ LP G +E Q F+ + + +L +GK F+ F S+E A+KA ++
Sbjct: 115 LRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFASQELAEKALGKHKE 174
Query: 61 HFNKSFIDTSRITVEFCKSFGDP 83
+I+ + + E +S+ DP
Sbjct: 175 RIGHRYIEVFKSSQEEVRSYSDP 197
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,279,282
Number of Sequences: 37866
Number of extensions: 2050945
Number of successful extensions: 30353
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 509
Number of HSP's successfully gapped in prelim test: 694
Number of HSP's that attempted gapping in prelim test: 14966
Number of HSP's gapped (non-prelim): 10334
length of query: 960
length of database: 18,247,518
effective HSP length: 112
effective length of query: 848
effective length of database: 14,006,526
effective search space: 11877534048
effective search space used: 11877534048
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.