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Search of human proteins with 226437606
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226437606 ankyrin repeat domain 34C [Homo sapiens]
(535 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226437606 ankyrin repeat domain 34C [Homo sapiens] 1063 0.0
gi|239745252 PREDICTED: ankyrin repeat domain 34C [Homo sapiens] 1063 0.0
gi|239756364 PREDICTED: ankyrin repeat domain 34C [Homo sapiens] 1061 0.0
gi|239750889 PREDICTED: ankyrin repeat domain 34C [Homo sapiens] 1061 0.0
gi|52138747 ankyrin repeat domain 34B [Homo sapiens] 371 e-102
gi|89941470 ankyrin repeat domain 34 [Homo sapiens] 344 1e-94
gi|121582655 ankyrin repeat domain 35 [Homo sapiens] 67 3e-11
gi|34304381 inversin isoform a [Homo sapiens] 64 3e-10
gi|34304379 inversin isoform b [Homo sapiens] 64 3e-10
gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo... 62 1e-09
gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo... 62 1e-09
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 62 1e-09
gi|17864094 feminization 1 homolog a [Homo sapiens] 61 2e-09
gi|126723390 ankyrin repeat domain 24 [Homo sapiens] 61 3e-09
gi|52856430 protein expressed in prostate, ovary, testis, and pl... 60 4e-09
gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo ... 60 4e-09
gi|52856434 POTE ankyrin domain family, member G [Homo sapiens] 60 5e-09
gi|224282147 prostate-specific P704P [Homo sapiens] 60 5e-09
gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens] 60 5e-09
gi|153792284 pote protein [Homo sapiens] 60 7e-09
gi|239747116 PREDICTED: hypothetical protein XP_002343915 isofor... 60 7e-09
gi|239747114 PREDICTED: hypothetical protein XP_002343914 isofor... 60 7e-09
gi|7657265 fem-1 homolog b [Homo sapiens] 60 7e-09
gi|134133226 protein expressed in prostate, ovary, testis, and p... 59 9e-09
gi|153791352 prostate, ovary, testis expressed protein on chromo... 59 9e-09
gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens] 59 1e-08
gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] 59 1e-08
gi|113413200 PREDICTED: similar to protein expressed in prostate... 58 2e-08
gi|239741769 PREDICTED: similar to protein expressed in prostate... 58 2e-08
gi|88953571 PREDICTED: similar to protein expressed in prostate,... 58 2e-08
>gi|226437606 ankyrin repeat domain 34C [Homo sapiens]
Length = 535
Score = 1063 bits (2750), Expect = 0.0
Identities = 535/535 (100%), Positives = 535/535 (100%)
Query: 1 MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQ 60
MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQ
Sbjct: 1 MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQ 60
Query: 61 SISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGA 120
SISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGA
Sbjct: 61 SISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGA 120
Query: 121 SALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRH 180
SALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRH
Sbjct: 121 SALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRH 180
Query: 181 SPPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLK 240
SPPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLK
Sbjct: 181 SPPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLK 240
Query: 241 RARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTN 300
RARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTN
Sbjct: 241 RARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTN 300
Query: 301 SIDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGP 360
SIDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGP
Sbjct: 301 SIDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGP 360
Query: 361 SGPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSR 420
SGPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSR
Sbjct: 361 SGPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSR 420
Query: 421 ESLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSS 480
ESLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSS
Sbjct: 421 ESLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSS 480
Query: 481 SKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT 535
SKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT
Sbjct: 481 SKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT 535
>gi|239745252 PREDICTED: ankyrin repeat domain 34C [Homo sapiens]
Length = 535
Score = 1063 bits (2750), Expect = 0.0
Identities = 535/535 (100%), Positives = 535/535 (100%)
Query: 1 MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQ 60
MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQ
Sbjct: 1 MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQ 60
Query: 61 SISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGA 120
SISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGA
Sbjct: 61 SISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGA 120
Query: 121 SALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRH 180
SALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRH
Sbjct: 121 SALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRH 180
Query: 181 SPPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLK 240
SPPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLK
Sbjct: 181 SPPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLK 240
Query: 241 RARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTN 300
RARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTN
Sbjct: 241 RARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTN 300
Query: 301 SIDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGP 360
SIDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGP
Sbjct: 301 SIDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGP 360
Query: 361 SGPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSR 420
SGPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSR
Sbjct: 361 SGPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSR 420
Query: 421 ESLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSS 480
ESLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSS
Sbjct: 421 ESLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSS 480
Query: 481 SKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT 535
SKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT
Sbjct: 481 SKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT 535
>gi|239756364 PREDICTED: ankyrin repeat domain 34C [Homo sapiens]
Length = 534
Score = 1061 bits (2745), Expect = 0.0
Identities = 534/534 (100%), Positives = 534/534 (100%)
Query: 2 MDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQS 61
MDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQS
Sbjct: 1 MDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQS 60
Query: 62 ISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGAS 121
ISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGAS
Sbjct: 61 ISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGAS 120
Query: 122 ALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHS 181
ALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHS
Sbjct: 121 ALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHS 180
Query: 182 PPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLKR 241
PPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLKR
Sbjct: 181 PPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLKR 240
Query: 242 ARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTNS 301
ARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTNS
Sbjct: 241 ARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTNS 300
Query: 302 IDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGPS 361
IDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGPS
Sbjct: 301 IDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGPS 360
Query: 362 GPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSRE 421
GPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSRE
Sbjct: 361 GPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSRE 420
Query: 422 SLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSSS 481
SLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSSS
Sbjct: 421 SLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSSS 480
Query: 482 KPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT 535
KPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT
Sbjct: 481 KPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT 534
>gi|239750889 PREDICTED: ankyrin repeat domain 34C [Homo sapiens]
Length = 534
Score = 1061 bits (2745), Expect = 0.0
Identities = 534/534 (100%), Positives = 534/534 (100%)
Query: 2 MDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQS 61
MDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQS
Sbjct: 1 MDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQS 60
Query: 62 ISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGAS 121
ISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGAS
Sbjct: 61 ISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGAS 120
Query: 122 ALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHS 181
ALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHS
Sbjct: 121 ALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHS 180
Query: 182 PPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLKR 241
PPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLKR
Sbjct: 181 PPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNEPGSPTRKVSNLKR 240
Query: 242 ARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTNS 301
ARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTNS
Sbjct: 241 ARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTNS 300
Query: 302 IDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGPS 361
IDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGPS
Sbjct: 301 IDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGPS 360
Query: 362 GPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSRE 421
GPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSRE
Sbjct: 361 GPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSRE 420
Query: 422 SLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSSS 481
SLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSSS
Sbjct: 421 SLDTVPSTSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSSS 480
Query: 482 KPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT 535
KPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT
Sbjct: 481 KPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT 534
>gi|52138747 ankyrin repeat domain 34B [Homo sapiens]
Length = 514
Score = 371 bits (952), Expect = e-102
Identities = 239/537 (44%), Positives = 318/537 (59%), Gaps = 31/537 (5%)
Query: 2 MDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQS 61
MD+ E+ ++GNSL+KAV RLRLTRLLLEGGAYINESND+GET LM+AC TKHVD QS
Sbjct: 1 MDEGMEISSEGNSLIKAVHQSRLRLTRLLLEGGAYINESNDRGETPLMIACKTKHVDHQS 60
Query: 62 ISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGAS 121
+SK+KMVKYLL+N ADPNIQDKSGKTAL+HAC+ +AG EVVSLLL++GAD SL+D + S
Sbjct: 61 VSKAKMVKYLLENNADPNIQDKSGKTALMHACLEKAGPEVVSLLLKSGADLSLQDHSSYS 120
Query: 122 ALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHS 181
ALVYAIN++D + LK LL ACKAKGKEVIIITT KS G TTKQYLN+PP ++ HS
Sbjct: 121 ALVYAINSEDTETLKVLLSACKAKGKEVIIITTAKSPCGKHTTKQYLNMPP-VDIDGCHS 179
Query: 182 PPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHP-SSCNTSKAVNEPGSPTRKVSNLK 240
P C +PS+I++K SPL+ + +L ++ +PGSP R K
Sbjct: 180 PATCTTPSEIDIKT--ASSPLSHSSETELTLFGFKDLELAGSNDDTWDPGSPVR-----K 232
Query: 241 RARLPQLKRLQSEPWGLIAPSVLAASTR----QDETHGASTDNEVIKSISDISFPKRGPL 296
A P+ +L P + +P +L R Q+E + + E+ + ++ KR +
Sbjct: 233 PALAPKGPKLPHAPPWVKSPPLLMHQNRVASLQEELQDITPEEELSYKTNGLALSKRF-I 291
Query: 297 SRTNSIDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEKC 356
+R SID KD +Q +S + ++ +G + +PVDQ+
Sbjct: 292 TRHQSIDVKDTAHLLRAFDQASSRKMSYDEINCQSYLSEGN------QQCIEVPVDQDPD 345
Query: 357 GMGPSGPSALKEPASLKWLENDLYDLDIQ--PGPDPPNSISLESGKGPLDRKKLNSSHLS 414
S L+ + L + Y D Q G PP S E GK + +KK+ S S
Sbjct: 346 SNQTIFASTLRSIVQKRNLGANHYSSDSQLSAGLTPPTS---EDGKALIGKKKILSPSPS 402
Query: 415 LFHGSRESLDTVPSTSPSSARRRPPHLLERRGSGTLLLDR-ISHTRPGFLPPLNVNLNPP 473
S+E L+ +P P RR +LE RGSG LD ++ TR GFLPPLNVN +PP
Sbjct: 403 QLSESKELLENIP---PGPLSRRNHAVLEGRGSGAFPLDHSVTQTRQGFLPPLNVNSHPP 459
Query: 474 IPDIRSSSKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDF 530
I DI ++K L+ G K ++P P PK + +SKK LLRR S+Q EQ+KQL +F
Sbjct: 460 ISDINVNNKICSLLSCGQKVLMPTVPIFPK--EFKSKKMLLRRQSLQTEQIKQLVNF 514
>gi|89941470 ankyrin repeat domain 34 [Homo sapiens]
Length = 496
Score = 344 bits (883), Expect = 1e-94
Identities = 233/547 (42%), Positives = 305/547 (55%), Gaps = 81/547 (14%)
Query: 8 LRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
L T+G++LL+AV G+LRL RLLLEGGAY+NE + +GETALM AC ++ D Q+ K++M
Sbjct: 2 LHTEGHALLRAVGQGKLRLARLLLEGGAYVNEGDAQGETALMAACRARYDDPQN--KARM 59
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
V+YLL+ ADPNI D+ G+TAL+HAC G V SLLL +GADPS+ D GASALV+A+
Sbjct: 60 VRYLLEQGADPNIADRLGRTALMHACAGGGGAAVASLLLAHGADPSVRDHAGASALVHAL 119
Query: 128 NADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVED----RHSPP 183
+ D++ L LLDACKAKG EVIIITTD S SGTK T+QYLN PPSP VED SP
Sbjct: 120 DRGDRETLATLLDACKAKGTEVIIITTDTSPSGTKKTRQYLNSPPSPGVEDPAPASPSPG 179
Query: 184 LCASPSDIELKAL-----GLDSPLTEKED---DFFSLQAGHPSSCNTSKAVNEPGSPTRK 235
C SPS+I+L+ G+ SP ++E+ D F P + SP+
Sbjct: 180 FCTSPSEIQLQTAGGGGRGMLSPRAQEEEEKRDVFEFPLPKPP---------DDPSPSEP 230
Query: 236 VSNLKRARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGP 295
+ R LKRL SEPWGL+AP T G + + ++ R
Sbjct: 231 LPKPPRHPPKPLKRLNSEPWGLVAP-----PQPVPPTEGRPGIERLTAEFNGLTLTGRPR 285
Query: 296 LSRTNSIDSKDPTLFHTVTEQVLKIPVSSAPASWKAAYEKGQAPHPRLARRGTLPVDQEK 355
LSR +S + + P W G L+RR T P QE
Sbjct: 286 LSRRHSTEGPED------------------PPPWAEKVTSGGP----LSRRNTAPEAQES 323
Query: 356 CGMGPSGPSALKEPASLKWLENDLYDLDIQPG---PDPPNSISLESGKGPLDRKKLNSSH 412
GP PS L++ S + +LD PG PD P ES + L+R++ ++S
Sbjct: 324 ---GP--PSGLRQKLS----RMEPVELD-TPGHLCPDSP-----ESSRLSLERRRYSASP 368
Query: 413 LSL-----FHGSRESLDTVP-STSPSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPL 466
L+L R+S +++P + SP S RRR P LLERRGSGTLLLD IS TRPGFLPPL
Sbjct: 369 LTLPPAGSAPSPRQSQESLPGAVSPLSGRRRSPGLLERRGSGTLLLDHISQTRPGFLPPL 428
Query: 467 NVNLNPPIPDIRSSSKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQ 526
NV+ +PPIPDIR G +P P + R+K+KL+RRHSMQ EQ++
Sbjct: 429 NVSPHPPIPDIRPQ-------PGGRAPSLPAPPYAGAPGSPRTKRKLVRRHSMQTEQIRL 481
Query: 527 LSDFEEI 533
L F+ +
Sbjct: 482 LGGFQSL 488
>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
Length = 1001
Score = 67.4 bits (163), Expect = 3e-11
Identities = 53/194 (27%), Positives = 90/194 (46%), Gaps = 23/194 (11%)
Query: 29 LLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGKTA 88
LL + A+++ ++ G T LM+A + H + + LL A N+ DK+ K+A
Sbjct: 138 LLCDHEAFLDVLDNDGRTPLMIASLGGH--------AAICSQLLQRGARVNVTDKNDKSA 189
Query: 89 LIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDAC--KAKG 146
LI AC + EV LLL +GAD D TG AL YA++ DK +HL A + +G
Sbjct: 190 LILAC-EKGSAEVAELLLSHGADAGAVDSTGHDALHYALHTQDKALWRHLQQALSRRRRG 248
Query: 147 KEVIIITTDKSSSGTKTTKQYLNVP-------PSPKVEDRHSPPLCASP-----SDIELK 194
+ ++ D +S + + Q + P P + E++ C+ + K
Sbjct: 249 GQRLVQHPDLASQASPSEPQAGSPPKSSWRAEPEEEQEEKEDEDPCSEEWRWKYEEERRK 308
Query: 195 ALGLDSPLTEKEDD 208
+ L+ L +K ++
Sbjct: 309 VVRLEQELVQKTEE 322
>gi|34304381 inversin isoform a [Homo sapiens]
Length = 1065
Score = 63.9 bits (154), Expect = 3e-10
Identities = 40/128 (31%), Positives = 74/128 (57%), Gaps = 13/128 (10%)
Query: 15 LLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDN 74
L +A +G + + L++GGA ++ + G + L A + + D + + L++N
Sbjct: 394 LFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNAD--------VCQILIEN 445
Query: 75 RADPNIQDKSGKTALIHACIRRAGGEV--VSLLLENGADPSLEDRTGASALVYAINADDK 132
+ +PN+QD +G+T L A GG + +++L+EN ADP+++D+ G +AL ++ N
Sbjct: 446 KINPNVQDYAGRTPLQCAAY---GGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYL 502
Query: 133 DALKHLLD 140
DA+K LLD
Sbjct: 503 DAIKLLLD 510
Score = 44.3 bits (103), Expect = 3e-04
Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 9/114 (7%)
Query: 27 TRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGK 86
T L L+ IN ++ G TAL A ++ HV VK LL+N A + D
Sbjct: 340 TMLSLKSDIDINMADKYGGTALHAAALSGHV--------STVKLLLENNAQVDATDVMKH 391
Query: 87 TALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLD 140
T L AC +V+ L++ GA L D+ G S L +A + D + L++
Sbjct: 392 TPLFRAC-EMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIE 444
>gi|34304379 inversin isoform b [Homo sapiens]
Length = 895
Score = 63.9 bits (154), Expect = 3e-10
Identities = 40/128 (31%), Positives = 74/128 (57%), Gaps = 13/128 (10%)
Query: 15 LLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDN 74
L +A +G + + L++GGA ++ + G + L A + + D + + L++N
Sbjct: 394 LFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNAD--------VCQILIEN 445
Query: 75 RADPNIQDKSGKTALIHACIRRAGGEV--VSLLLENGADPSLEDRTGASALVYAINADDK 132
+ +PN+QD +G+T L A GG + +++L+EN ADP+++D+ G +AL ++ N
Sbjct: 446 KINPNVQDYAGRTPLQCAAY---GGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYL 502
Query: 133 DALKHLLD 140
DA+K LLD
Sbjct: 503 DAIKLLLD 510
Score = 44.3 bits (103), Expect = 3e-04
Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 9/114 (7%)
Query: 27 TRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGK 86
T L L+ IN ++ G TAL A ++ HV VK LL+N A + D
Sbjct: 340 TMLSLKSDIDINMADKYGGTALHAAALSGHV--------STVKLLLENNAQVDATDVMKH 391
Query: 87 TALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLD 140
T L AC +V+ L++ GA L D+ G S L +A + D + L++
Sbjct: 392 TPLFRAC-EMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIE 444
>gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo
sapiens]
Length = 452
Score = 62.4 bits (150), Expect = 1e-09
Identities = 45/132 (34%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D L +A W G + R +++ G IN+ + K TAL +AC S++
Sbjct: 63 REDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACAN--------GNSEV 114
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
V LLD + ++ D +TALI A ++ E +LL++G DP+L D G +AL YA+
Sbjct: 115 VSLLLDRQCQLHVFDSKKRTALIKA-VQCQEDECALMLLQHGTDPNLPDMYGNTALHYAV 173
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 174 YNEDKLMAKTLL 185
Score = 29.6 bits (65), Expect = 7.2
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 9/76 (11%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L AV+ + + LL GA I N G T L++A + K +MVK+
Sbjct: 165 GNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQ--------KQRMVKF 216
Query: 71 LLDNRADPNIQDKSGK 86
L+ +A+ N D+ G+
Sbjct: 217 LIKKKANLNALDRFGR 232
>gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo
sapiens]
Length = 498
Score = 62.4 bits (150), Expect = 1e-09
Identities = 45/132 (34%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D L +A W G + R +++ G IN+ + K TAL +AC S++
Sbjct: 63 REDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACAN--------GNSEV 114
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
V LLD + ++ D +TALI A ++ E +LL++G DP+L D G +AL YA+
Sbjct: 115 VSLLLDRQCQLHVFDSKKRTALIKA-VQCQEDECALMLLQHGTDPNLPDMYGNTALHYAV 173
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 174 YNEDKLMAKTLL 185
Score = 52.0 bits (123), Expect = 1e-06
Identities = 41/119 (34%), Positives = 63/119 (52%), Gaps = 10/119 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L AV+ + + LL GA I N G T L++A + K +MVK+
Sbjct: 165 GNTALHYAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQ--------KQRMVKF 216
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINA 129
L+ +A+ N D+ G+TALI A +R +VSLLL+ D +D G +A YA+++
Sbjct: 217 LIKKKANLNALDRFGRTALILA-VRCGSASIVSLLLQQNIDVFSQDVFGQTAEDYAVSS 274
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 62.4 bits (150), Expect = 1e-09
Identities = 66/252 (26%), Positives = 111/252 (44%), Gaps = 32/252 (12%)
Query: 5 DTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISK 64
D + RT +L A W G + LL+ GA +N+++++G TAL+ A H
Sbjct: 641 DADSRT---ALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGH-------- 689
Query: 65 SKMVKYLLDNRADPNIQDKSGKTALIHA--CIRRAGG--EVVSLLLENGADPSLEDRTGA 120
++V++LLD+ A+ N +D G+TAL A C+ + G VVSLL++ GA+ D+ G
Sbjct: 690 REIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGM 749
Query: 121 SALVYAINADDKDALKHLL------DACKAKGKEVIIITTDKSSSGTKTTKQYLNVP-PS 173
+ L+ A D + LL D G+ ++ + T + S
Sbjct: 750 TPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDS 809
Query: 174 PKVEDRHSPPLCASPSDIELKALGLDSPLTEKEDD-------FFSLQAGHPSSCNTSKAV 226
E R + ++ ++E+ LD L E D + GH C +A+
Sbjct: 810 IDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLIC---EAL 866
Query: 227 NEPGSPTRKVSN 238
E G+ T ++ N
Sbjct: 867 IEQGARTNEIDN 878
Score = 57.0 bits (136), Expect = 4e-08
Identities = 31/98 (31%), Positives = 57/98 (58%), Gaps = 9/98 (9%)
Query: 13 NSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLL 72
++L A W G +++ +LL+E GA ++ + ++G TAL +A H+D +V+ LL
Sbjct: 1014 SALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHID--------VVQVLL 1065
Query: 73 DNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGA 110
++ ADPN D+ G+TA+ + +++ LL + GA
Sbjct: 1066 EHGADPNHADQFGRTAM-RVAAKNGHSQIIKLLEKYGA 1102
Score = 50.4 bits (119), Expect = 4e-06
Identities = 32/99 (32%), Positives = 54/99 (54%), Gaps = 11/99 (11%)
Query: 28 RLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGKT 87
+LL++ GA++N +D+ +CI + Q++ + ++ LLDN A N D +G+T
Sbjct: 498 QLLVKAGAHVNSEDDR------TSCIVR----QALEREDSIRTLLDNGASVNQCDSNGRT 547
Query: 88 ALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYA 126
L +A +VV+LL+ GAD +ED G + L A
Sbjct: 548 LLANAAY-SGSLDVVNLLVSRGADLEIEDAHGHTPLTLA 585
Score = 49.3 bits (116), Expect = 9e-06
Identities = 41/131 (31%), Positives = 63/131 (48%), Gaps = 10/131 (7%)
Query: 11 DGNSLLKAVWL-GRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVK 69
DG L + L +L + LE GA + S+ +G TAL V+C H++ MV+
Sbjct: 945 DGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHME--------MVQ 996
Query: 70 YLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINA 129
L+ AD N D ++AL + + +VV LL+E+GA GA+AL A
Sbjct: 997 VLIAYHADVNAADNEKRSAL-QSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQE 1055
Query: 130 DDKDALKHLLD 140
D ++ LL+
Sbjct: 1056 GHIDVVQVLLE 1066
Score = 47.8 bits (112), Expect = 3e-05
Identities = 41/136 (30%), Positives = 68/136 (50%), Gaps = 16/136 (11%)
Query: 5 DTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISK 64
D E RT +L + W G + + ++L+ A +N ++++ +AL A HV
Sbjct: 976 DAEGRT---ALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHV------- 1025
Query: 65 SKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGG--EVVSLLLENGADPSLEDRTGASA 122
K+V+ L+++ A + G TAL CI G +VV +LLE+GADP+ D+ G +A
Sbjct: 1026 -KVVQLLIEHGAVVDHTCNQGATAL---CIAAQEGHIDVVQVLLEHGADPNHADQFGRTA 1081
Query: 123 LVYAINADDKDALKHL 138
+ A +K L
Sbjct: 1082 MRVAAKNGHSQIIKLL 1097
Score = 38.5 bits (88), Expect = 0.016
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 18 AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRAD 77
A + G + L+E GA NE ++ G ++A H D V+ LL+N+++
Sbjct: 854 AAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYD--------CVQILLENKSN 905
Query: 78 PNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASAL 123
+ + G+ AL A + ++V LL +GAD + +D G L
Sbjct: 906 IDQRGYDGRNALRVAAL-EGHRDIVELLFSHGADVNCKDADGRPTL 950
Score = 38.5 bits (88), Expect = 0.016
Identities = 33/118 (27%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 7 ELRTDGN-SLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKS 65
E+ DG + A G ++LLE + I++ G AL VA + H D
Sbjct: 875 EIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRD------- 927
Query: 66 KMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASAL 123
+V+ L + AD N +D G+ L + + LENGA+ D G +AL
Sbjct: 928 -IVELLFSHGADVNCKDADGRPTLYILALENQ-LTMAEYFLENGANVEASDAEGRTAL 983
>gi|17864094 feminization 1 homolog a [Homo sapiens]
Length = 617
Score = 61.2 bits (147), Expect = 2e-09
Identities = 43/143 (30%), Positives = 70/143 (48%), Gaps = 9/143 (6%)
Query: 22 GRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQ 81
G L++ + LL GA +N + T L AC H++ +VKYL++++AD +
Sbjct: 94 GHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLE--------IVKYLVEHKADLEVS 145
Query: 82 DKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDA 141
++ G T L+ +C + E+ LLE GAD + + G +AL + D +K LL
Sbjct: 146 NRHGHTCLMISCYK-GHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMY 204
Query: 142 CKAKGKEVIIITTDKSSSGTKTT 164
C K+ +T S+S T T
Sbjct: 205 CAKMEKDGYGMTPLLSASVTGHT 227
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 9/97 (9%)
Query: 10 TDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVK 69
T+ L A + G L + + L+E A + SN G T LM++C H ++ +
Sbjct: 115 TNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGH--------KEIAQ 166
Query: 70 YLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLL 106
YLL+ AD N + G TAL H C +++ +LL
Sbjct: 167 YLLEKGADVNRKSVKGNTAL-HDCAESGSLDIMKMLL 202
>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
Length = 1146
Score = 60.8 bits (146), Expect = 3e-09
Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 9/162 (5%)
Query: 22 GRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQ 81
G L + +L A++N + G T L++A H D + + LL A N Q
Sbjct: 159 GCLSCSEVLCSFKAHLNPQDRSGATPLIIAAQMCHTD--------LCRLLLQQGAAANDQ 210
Query: 82 DKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDA 141
D G+TAL+ AC A E V +LL+ GA P + D G A Y A DK L L +A
Sbjct: 211 DLQGRTALMLAC-EGASPETVEVLLQGGAQPGITDALGQDAAHYGALAGDKLILHLLQEA 269
Query: 142 CKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHSPP 183
+ + D + ++ + +PK PP
Sbjct: 270 AQRPSPPSALTEDDSGEASSQNSMSSHGKQGAPKKRKAPPPP 311
Score = 43.1 bits (100), Expect = 6e-04
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 10/102 (9%)
Query: 9 RTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMV 68
R+ L+ A + L RLLL+ GA N+ + +G TALM+AC + + V
Sbjct: 179 RSGATPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLAC--------EGASPETV 230
Query: 69 KYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGA 110
+ LL A P I D G+ A + + AG +++ LL+ A
Sbjct: 231 EVLLQGGAQPGITDALGQDAAHYGAL--AGDKLILHLLQEAA 270
Score = 36.2 bits (82), Expect = 0.077
Identities = 59/257 (22%), Positives = 103/257 (40%), Gaps = 34/257 (13%)
Query: 6 TELRTDGNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISK 64
T+L +G S A G +++ G+ + ++ G AL +A H
Sbjct: 76 TKLDPEGKSAFHLAAMRGAASCLEVMIAHGSNVMSADGAGYNALHLAAKYGH-------- 127
Query: 65 SKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGG--EVVSLLLENGADPSLEDRTGASA 122
+ +K LL ++ D SG TAL HA AGG +L A + +DR+GA+
Sbjct: 128 PQCLKQLLQASCVVDVVDSSGWTALHHAA---AGGCLSCSEVLCSFKAHLNPQDRSGATP 184
Query: 123 LVYAINADDKDALKHLLDACKA------KGKEVIIITTDKSSSGTKTTKQYLNVPPSPKV 176
L+ A D + LL A +G+ +++ + +S +T + L P +
Sbjct: 185 LIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLACEGAS--PETVEVLLQGGAQPGI 242
Query: 177 ED------RHSPPLCASPSDIEL--KALGLDSPLTEKEDDFFSLQAGHPSSCNTSKAVNE 228
D H L + L +A SP + +D +G SS N+ + +
Sbjct: 243 TDALGQDAAHYGALAGDKLILHLLQEAAQRPSPPSALTED----DSGEASSQNSMSSHGK 298
Query: 229 PGSPTRKVSNLKRARLP 245
G+P ++ + A +P
Sbjct: 299 QGAPKKRKAPPPPASIP 315
>gi|52856430 protein expressed in prostate, ovary, testis, and
placenta 15 [Homo sapiens]
Length = 581
Score = 60.5 bits (145), Expect = 4e-09
Identities = 45/132 (34%), Positives = 71/132 (53%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S++
Sbjct: 137 REDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASAN--------GNSEV 188
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
V+ LLD R N+ D +TALI A ++ E V +LLE+GAD +++D G +AL YAI
Sbjct: 189 VQLLLDRRCQLNVLDNKKRTALIKA-VQCQEDECVLMLLEHGADGNIQDEYGNTALHYAI 247
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 248 YNEDKLMAKALL 259
Score = 53.1 bits (126), Expect = 6e-07
Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 239 GNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLG-----VHEQ---KQQVVKF 290
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N D+ G+TALI A + +V+LLLE D S +D +G +A YA+++
Sbjct: 291 LIKKKANLNALDRYGRTALILA-VCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSH 349
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ I+++ S+
Sbjct: 350 HHVICELLSD---YKEKQMLKISSENSN 374
Score = 33.1 bits (74), Expect = 0.65
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 77 DPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALK 136
D N +DK +TAL H EVV LLL+ ++ D +AL+ A+ + + +
Sbjct: 165 DMNKRDKQKRTAL-HLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVL 223
Query: 137 HLLD 140
LL+
Sbjct: 224 MLLE 227
>gi|239745058 PREDICTED: hypothetical protein XP_002343353 [Homo
sapiens]
Length = 544
Score = 60.5 bits (145), Expect = 4e-09
Identities = 45/132 (34%), Positives = 71/132 (53%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S++
Sbjct: 100 REDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASAN--------GNSEV 151
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
V+ LLD R N+ D +TALI A ++ E V +LLE+GAD +++D G +AL YAI
Sbjct: 152 VQLLLDRRCQLNVLDNKKRTALIKA-VQCQEDECVLMLLEHGADGNIQDEYGNTALHYAI 210
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 211 YNEDKLMAKALL 222
Score = 53.1 bits (126), Expect = 6e-07
Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 202 GNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLG-----VHEQ---KQEVVKF 253
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N D+ G+TALI A + +V+LLLE D S +D +G +A YA+++
Sbjct: 254 LIKKKANLNALDRYGRTALILA-VCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSH 312
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ I+++ S+
Sbjct: 313 HHVICELLSD---YKEKQMLKISSENSN 337
Score = 33.1 bits (74), Expect = 0.65
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 77 DPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALK 136
D N +DK +TAL H EVV LLL+ ++ D +AL+ A+ + + +
Sbjct: 128 DMNKRDKQKRTAL-HLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVL 186
Query: 137 HLLD 140
LL+
Sbjct: 187 MLLE 190
>gi|52856434 POTE ankyrin domain family, member G [Homo sapiens]
Length = 508
Score = 60.1 bits (144), Expect = 5e-09
Identities = 45/132 (34%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S++
Sbjct: 137 REDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASAN--------GNSEV 188
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
VK LLD R NI D +TAL A ++ E +LLE+G DP++ D G +AL YAI
Sbjct: 189 VKLLLDRRCQLNILDNKKRTALTKA-VQCREDECALMLLEHGTDPNIPDEYGNTALHYAI 247
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 248 YNEDKLMAKALL 259
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 239 GNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQ---KQQVVKF 290
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N D+ G+TALI A + +VSLLLE D S +D +G +A YA+++
Sbjct: 291 LIKKKANLNALDRYGRTALILA-VCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSH 349
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ ++++ S+
Sbjct: 350 HNVICQLLSD---YKEKQMLKVSSENSN 374
>gi|224282147 prostate-specific P704P [Homo sapiens]
Length = 508
Score = 60.1 bits (144), Expect = 5e-09
Identities = 45/132 (34%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S++
Sbjct: 137 REDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASAN--------GNSEV 188
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
VK LLD R NI D +TAL A ++ E +LLE+G DP++ D G +AL YAI
Sbjct: 189 VKLLLDRRCQLNILDNKKRTALTKA-VQCQEDECALMLLEHGTDPNIPDEYGNTALHYAI 247
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 248 YNEDKLMAKALL 259
Score = 53.5 bits (127), Expect = 5e-07
Identities = 45/148 (30%), Positives = 78/148 (52%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 239 GNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQ---KQQVVKF 290
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N D+ G+T LI A + +VSLLLE D S +D +G +A YA+++
Sbjct: 291 LIKKKANLNALDRYGRTVLILA-VCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSR 349
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ ++++ S+
Sbjct: 350 HNVICQLLSD---YKEKQILKVSSENSN 374
>gi|209977003 ANKRD26-like family C, member 3 [Homo sapiens]
Length = 545
Score = 60.1 bits (144), Expect = 5e-09
Identities = 45/132 (34%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S++
Sbjct: 174 REDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASAN--------GNSEV 225
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
VK LLD R NI D +TAL A ++ E +LLE+G DP++ D G +AL YAI
Sbjct: 226 VKLLLDRRCQLNILDNKKRTALTKA-VQCQEDECALMLLEHGTDPNIPDEYGNTALHYAI 284
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 285 YNEDKLMAKALL 296
Score = 55.1 bits (131), Expect = 2e-07
Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 276 GNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQ---KQQVVKF 327
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N D+ G+TALI A + +VSLLLE D S +D +G +A YA+++
Sbjct: 328 LIKKKANLNALDRYGRTALILA-VCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSR 386
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ ++++ S+
Sbjct: 387 HNVICQLLSD---YKEKQILKVSSENSN 411
>gi|153792284 pote protein [Homo sapiens]
Length = 584
Score = 59.7 bits (143), Expect = 7e-09
Identities = 46/132 (34%), Positives = 70/132 (53%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S++
Sbjct: 137 REDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASAN--------GNSEV 188
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
V+ LLD R N+ D +TALI A I+ E V +LLE+GAD ++ D G +AL YAI
Sbjct: 189 VQLLLDRRCQLNVLDNKKRTALIKA-IQCQEDECVLMLLEHGADRNIPDEYGNTALHYAI 247
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 248 YNEDKLMAKALL 259
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/148 (31%), Positives = 80/148 (54%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 239 GNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLG-----VHEQ---KQQVVKF 290
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N+ D+ G+TALI A + +V+LLLE D S +D +G +A YA+++
Sbjct: 291 LIKKKANLNVLDRYGRTALILA-VCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSH 349
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ I+++ S+
Sbjct: 350 HHVICELLSD---YKEKQMLKISSENSN 374
Score = 43.1 bits (100), Expect = 6e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 9/118 (7%)
Query: 22 GRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQ 81
G + +LLL+ +N ++K TAL+ A + + V LL++ AD NI
Sbjct: 184 GNSEVVQLLLDRRCQLNVLDNKKRTALIKAI--------QCQEDECVLMLLEHGADRNIP 235
Query: 82 DKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLL 139
D+ G TAL H I + LL GAD +++ G + L+ ++ + +K L+
Sbjct: 236 DEYGNTAL-HYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLI 292
Score = 33.5 bits (75), Expect = 0.50
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 77 DPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALK 136
D N +DK +TAL H EVV LLL+ ++ D +AL+ AI + + +
Sbjct: 165 DMNKRDKEKRTAL-HLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVL 223
Query: 137 HLLD 140
LL+
Sbjct: 224 MLLE 227
>gi|239747116 PREDICTED: hypothetical protein XP_002343915 isoform 2
[Homo sapiens]
Length = 551
Score = 59.7 bits (143), Expect = 7e-09
Identities = 46/132 (34%), Positives = 70/132 (53%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S++
Sbjct: 104 REDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASAN--------GNSEV 155
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
V+ LLD R N+ D +TALI A I+ E V +LLE+GAD ++ D G +AL YAI
Sbjct: 156 VQLLLDRRCQLNVLDNKKRTALIKA-IQCQEDECVLMLLEHGADRNIPDEYGNTALHYAI 214
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 215 YNEDKLMAKALL 226
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/148 (31%), Positives = 80/148 (54%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 206 GNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLG-----VHEQ---KQQVVKF 257
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N+ D+ G+TALI A + +V+LLLE D S +D +G +A YA+++
Sbjct: 258 LIKKKANLNVLDRYGRTALILA-VCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSH 316
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ I+++ S+
Sbjct: 317 HHVICELLSD---YKEKQMLKISSENSN 341
Score = 43.1 bits (100), Expect = 6e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 9/118 (7%)
Query: 22 GRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQ 81
G + +LLL+ +N ++K TAL+ A + + V LL++ AD NI
Sbjct: 151 GNSEVVQLLLDRRCQLNVLDNKKRTALIKAI--------QCQEDECVLMLLEHGADRNIP 202
Query: 82 DKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLL 139
D+ G TAL H I + LL GAD +++ G + L+ ++ + +K L+
Sbjct: 203 DEYGNTAL-HYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLI 259
Score = 33.5 bits (75), Expect = 0.50
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 77 DPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALK 136
D N +DK +TAL H EVV LLL+ ++ D +AL+ AI + + +
Sbjct: 132 DMNKRDKEKRTAL-HLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVL 190
Query: 137 HLLD 140
LL+
Sbjct: 191 MLLE 194
>gi|239747114 PREDICTED: hypothetical protein XP_002343914 isoform 1
[Homo sapiens]
Length = 584
Score = 59.7 bits (143), Expect = 7e-09
Identities = 46/132 (34%), Positives = 70/132 (53%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S++
Sbjct: 137 REDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKEKRTALHLASAN--------GNSEV 188
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
V+ LLD R N+ D +TALI A I+ E V +LLE+GAD ++ D G +AL YAI
Sbjct: 189 VQLLLDRRCQLNVLDNKKRTALIKA-IQCQEDECVLMLLEHGADRNIPDEYGNTALHYAI 247
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 248 YNEDKLMAKALL 259
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/148 (31%), Positives = 80/148 (54%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 239 GNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLG-----VHEQ---KQQVVKF 290
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N+ D+ G+TALI A + +V+LLLE D S +D +G +A YA+++
Sbjct: 291 LIKKKANLNVLDRYGRTALILA-VCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSH 349
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ I+++ S+
Sbjct: 350 HHVICELLSD---YKEKQMLKISSENSN 374
Score = 43.1 bits (100), Expect = 6e-04
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 9/118 (7%)
Query: 22 GRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQ 81
G + +LLL+ +N ++K TAL+ A + + V LL++ AD NI
Sbjct: 184 GNSEVVQLLLDRRCQLNVLDNKKRTALIKAI--------QCQEDECVLMLLEHGADRNIP 235
Query: 82 DKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLL 139
D+ G TAL H I + LL GAD +++ G + L+ ++ + +K L+
Sbjct: 236 DEYGNTAL-HYAIYNEDKLMAKALLLYGADIESKNKCGLTPLLLGVHEQKQQVVKFLI 292
Score = 33.5 bits (75), Expect = 0.50
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 77 DPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALK 136
D N +DK +TAL H EVV LLL+ ++ D +AL+ AI + + +
Sbjct: 165 DMNKRDKEKRTAL-HLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAIQCQEDECVL 223
Query: 137 HLLD 140
LL+
Sbjct: 224 MLLE 227
>gi|7657265 fem-1 homolog b [Homo sapiens]
Length = 627
Score = 59.7 bits (143), Expect = 7e-09
Identities = 40/122 (32%), Positives = 61/122 (50%), Gaps = 9/122 (7%)
Query: 18 AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRAD 77
A G + +LL+ GA +N + T L AC +D +VKYL++N A+
Sbjct: 95 AAGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLD--------IVKYLVENNAN 146
Query: 78 PNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKH 137
+I +K T L+ A + +VV LLE ADP+ + GA+AL +A A D +K
Sbjct: 147 ISIANKYDNTCLMIAAYK-GHTDVVRYLLEQRADPNAKAHCGATALHFAAEAGHIDIVKE 205
Query: 138 LL 139
L+
Sbjct: 206 LI 207
Score = 52.4 bits (124), Expect = 1e-06
Identities = 42/146 (28%), Positives = 64/146 (43%), Gaps = 22/146 (15%)
Query: 10 TDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVK 69
T+ L A + GRL + + L+E A I+ +N T LM+A H D +V+
Sbjct: 120 TNSTPLRAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTD--------VVR 171
Query: 70 YLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINA 129
YLL+ RADPN + G TAL H ++V L++ A +N
Sbjct: 172 YLLEQRADPNAKAHCGATAL-HFAAEAGHIDIVKELIKWRA-------------AIVVNG 217
Query: 130 DDKDALKHLLDACKAKGKEVIIITTD 155
LK ++CKA E+++ D
Sbjct: 218 HGMTPLKVAAESCKADVVELLLSHAD 243
>gi|134133226 protein expressed in prostate, ovary, testis, and
placenta 2 [Homo sapiens]
Length = 1075
Score = 59.3 bits (142), Expect = 9e-09
Identities = 43/130 (33%), Positives = 67/130 (51%), Gaps = 10/130 (7%)
Query: 11 DGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVK 69
D + L +A W G++ R +++ +N+ + + TAL +A S++VK
Sbjct: 139 DLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASAN--------GNSEVVK 190
Query: 70 YLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINA 129
LLD R N+ D +TALI A ++ E +LLE+G DP++ D G + L YAI
Sbjct: 191 LLLDRRCQLNVLDNKKRTALIKA-VQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYN 249
Query: 130 DDKDALKHLL 139
+DK K LL
Sbjct: 250 EDKLMAKALL 259
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/148 (31%), Positives = 79/148 (53%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 239 GNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQ---KQQVVKF 290
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N D+ G+TALI A + +VSLLLE D S +D +G +A YA+++
Sbjct: 291 LIKKKANLNALDRYGRTALILA-VCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSH 349
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ I+++ S+
Sbjct: 350 HHVICQLLSD---YKEKQMLKISSENSN 374
Score = 32.3 bits (72), Expect = 1.1
Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 77 DPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALK 136
D N +DK +TAL H EVV LLL+ ++ D +AL+ A+ + +
Sbjct: 165 DVNKKDKQKRTAL-HLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECAL 223
Query: 137 HLLD 140
LL+
Sbjct: 224 MLLE 227
>gi|153791352 prostate, ovary, testis expressed protein on
chromosome 2 [Homo sapiens]
Length = 1075
Score = 59.3 bits (142), Expect = 9e-09
Identities = 43/130 (33%), Positives = 67/130 (51%), Gaps = 10/130 (7%)
Query: 11 DGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVK 69
D + L +A W G++ R +++ +N+ + + TAL +A S++VK
Sbjct: 139 DLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASAN--------GNSEVVK 190
Query: 70 YLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINA 129
LLD R N+ D +TALI A ++ E +LLE+G DP++ D G + L YAI
Sbjct: 191 LLLDRRCQLNVLDNKKRTALIKA-VQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAIYN 249
Query: 130 DDKDALKHLL 139
+DK K LL
Sbjct: 250 EDKLMAKALL 259
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/148 (31%), Positives = 79/148 (53%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 239 GNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQ---KQQVVKF 290
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N D+ G+TALI A + +VSLLLE D S +D +G +A YA+++
Sbjct: 291 LIKKKANLNALDRYGRTALILA-VCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSH 349
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ I+++ S+
Sbjct: 350 HHVICQLLSD---YKEKQMLKISSENSN 374
Score = 33.9 bits (76), Expect = 0.38
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 77 DPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALK 136
D N QDK +TAL H EVV LLL+ ++ D +AL+ A+ + +
Sbjct: 165 DVNKQDKQKRTAL-HLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECAL 223
Query: 137 HLLD 140
LL+
Sbjct: 224 MLLE 227
>gi|212549546 ANKRD26-like family B, member 2 [Homo sapiens]
Length = 542
Score = 58.9 bits (141), Expect = 1e-08
Identities = 43/132 (32%), Positives = 70/132 (53%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S++
Sbjct: 137 REDLDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASAN--------GNSEV 188
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
V+ LLD R N+ D +TALI A ++ E V +LLE+GAD ++ D G + L YA+
Sbjct: 189 VQLLLDRRCQLNVLDNKKRTALIKA-VQCQEDECVLMLLEHGADQNIPDEYGNTTLHYAV 247
Query: 128 NADDKDALKHLL 139
+ +DK K LL
Sbjct: 248 HNEDKLMAKALL 259
Score = 52.8 bits (125), Expect = 8e-07
Identities = 42/133 (31%), Positives = 72/133 (54%), Gaps = 12/133 (9%)
Query: 26 LTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSG 85
+ + LL GA I N G T L++ V +Q K ++VK+L+ +A+ N D+ G
Sbjct: 254 MAKALLLYGADIESKNKCGLTPLLLG-----VHEQ---KQQVVKFLIKKKANLNALDRYG 305
Query: 86 KTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDACKAK 145
+TALI A + +V+LLLE D S +D +G +A YA+++ + L D K
Sbjct: 306 RTALILA-VCCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSD---YK 361
Query: 146 GKEVIIITTDKSS 158
K+++ I+++ S+
Sbjct: 362 EKQMLKISSENSN 374
Score = 33.1 bits (74), Expect = 0.65
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 77 DPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALK 136
D N +DK +TAL H EVV LLL+ ++ D +AL+ A+ + + +
Sbjct: 165 DMNKRDKQKRTAL-HLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQEDECVL 223
Query: 137 HLLD 140
LL+
Sbjct: 224 MLLE 227
>gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]
Length = 1050
Score = 58.9 bits (141), Expect = 1e-08
Identities = 47/120 (39%), Positives = 64/120 (53%), Gaps = 14/120 (11%)
Query: 11 DGNSLLKAVWL-GRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVK 69
DG+S L L GR L LLL+ GA N L +AC H ++VK
Sbjct: 743 DGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVPLHLACQQGHF--------QVVK 794
Query: 70 YLLDNRADPNIQDKSGKTALIHACIRRAGG--EVVSLLLENGADPSLEDRTGASALVYAI 127
LLD+ A PN +D SG T LI+AC +GG E+V+LLL++GA + + G +AL A+
Sbjct: 795 CLLDSNAKPNKKDLSGNTPLIYAC---SGGHHELVALLLQHGASINASNNKGNTALHEAV 851
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/79 (40%), Positives = 43/79 (54%), Gaps = 9/79 (11%)
Query: 12 GNS-LLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L+ A G L LLL+ GA IN SN+KG TAL A I KHV +V+
Sbjct: 810 GNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVIEKHV--------FVVEL 861
Query: 71 LLDNRADPNIQDKSGKTAL 89
LL + A + +K +TA+
Sbjct: 862 LLLHGASVQVLNKRQRTAV 880
Score = 38.1 bits (87), Expect = 0.020
Identities = 53/213 (24%), Positives = 92/213 (43%), Gaps = 20/213 (9%)
Query: 22 GRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDN-RADPNI 80
G +T LLL A ++ G T L +AC H D +V Y +++ R D I
Sbjct: 507 GYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHED----CVKALVYYDVESCRLD--I 560
Query: 81 QDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALK--HL 138
++ G T L H R V+ LL+NGA +++R + L A+N+ ++ HL
Sbjct: 561 GNEKGDTPL-HIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKILSVMEAYHL 619
Query: 139 LDACKAKGKEVIIITTDK---SSSGTKTTKQYLNVPPSPKVED-----RHSPPLCASPSD 190
+ K E + + + S S +T + ++ S + E+ R L + +D
Sbjct: 620 SFERRQKSSEAPVQSPQRSVDSISQESSTSSFSSMSASSRQEETKKDYREVEKLLRAVAD 679
Query: 191 IELKALGLDSPLTEK--EDDFFSLQAGHPSSCN 221
+L+ + TE+ ED ++ A P C+
Sbjct: 680 GDLEMVRYLLEWTEEDLEDAEDTVSAADPEFCH 712
Score = 37.7 bits (86), Expect = 0.027
Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 22 GRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQ 81
G ++ + LL+ A N+ + G T L+ AC H ++V LL + A N
Sbjct: 788 GHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGH--------HELVALLLQHGASINAS 839
Query: 82 DKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDA 141
+ G TAL H + VV LLL +GA + ++ +A+ A L ++ +
Sbjct: 840 NNKGNTAL-HEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSKIMELLQVVPS 898
Query: 142 CKAKGKEV 149
C A +V
Sbjct: 899 CVASLDDV 906
>gi|113413200 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 1038
Score = 57.8 bits (138), Expect = 2e-08
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S +
Sbjct: 100 REDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASAN--------GNSGV 151
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
VK LLD R N+ D +TAL A ++ E +LLE+G DP++ D G + L YAI
Sbjct: 152 VKLLLDRRCQLNVLDNKKRTALTKA-VQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAI 210
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 211 YNEDKLMAKALL 222
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/148 (31%), Positives = 79/148 (53%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 202 GNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQ---KQQVVKF 253
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N D+ G+TALI A + +VSLLLE D S +D +G +A YA+++
Sbjct: 254 LIKKKANLNALDRYGRTALILA-VCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSH 312
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ I+++ S+
Sbjct: 313 HHVICQLLSD---YKEKQMLKISSENSN 337
>gi|239741769 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 [Homo sapiens]
Length = 952
Score = 57.8 bits (138), Expect = 2e-08
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S +
Sbjct: 137 REDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASAN--------GNSGV 188
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
VK LLD R N+ D +TAL A ++ E +LLE+G DP++ D G + L YAI
Sbjct: 189 VKLLLDRRCQLNVLDNKKRTALTKA-VQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAI 247
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 248 YNEDKLMAKALL 259
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/148 (31%), Positives = 79/148 (53%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 239 GNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQ---KQQVVKF 290
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N D+ G+TALI A + +VSLLLE D S +D +G +A YA+++
Sbjct: 291 LIKKKANLNALDRYGRTALILA-VCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSH 349
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ I+++ S+
Sbjct: 350 HHVICQLLSD---YKEKQMLKISSENSN 374
>gi|88953571 PREDICTED: similar to protein expressed in prostate,
ovary, testis, and placenta 2 isoform 2 [Homo sapiens]
Length = 1075
Score = 57.8 bits (138), Expect = 2e-08
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 10/132 (7%)
Query: 9 RTDGNSLLKAVWLGRL-RLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKM 67
R D + L +A W G++ R +++ +N+ + + TAL +A S +
Sbjct: 137 REDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASAN--------GNSGV 188
Query: 68 VKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAI 127
VK LLD R N+ D +TAL A ++ E +LLE+G DP++ D G + L YAI
Sbjct: 189 VKLLLDRRCQLNVLDNKKRTALTKA-VQCQEDECALMLLEHGTDPNIPDEYGNTTLHYAI 247
Query: 128 NADDKDALKHLL 139
+DK K LL
Sbjct: 248 YNEDKLMAKALL 259
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/148 (31%), Positives = 79/148 (53%), Gaps = 13/148 (8%)
Query: 12 GNSLLK-AVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKY 70
GN+ L A++ + + LL GA I N G T L++ V +Q K ++VK+
Sbjct: 239 GNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLG-----VHEQ---KQQVVKF 290
Query: 71 LLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINAD 130
L+ +A+ N D+ G+TALI A + +VSLLLE D S +D +G +A YA+++
Sbjct: 291 LIKKKANLNALDRYGRTALILA-VCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSH 349
Query: 131 DKDALKHLLDACKAKGKEVIIITTDKSS 158
+ L D K K+++ I+++ S+
Sbjct: 350 HHVICQLLSD---YKEKQMLKISSENSN 374
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,455,931
Number of Sequences: 37866
Number of extensions: 1239133
Number of successful extensions: 4902
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 186
Number of HSP's successfully gapped in prelim test: 215
Number of HSP's that attempted gapping in prelim test: 3459
Number of HSP's gapped (non-prelim): 1068
length of query: 535
length of database: 18,247,518
effective HSP length: 107
effective length of query: 428
effective length of database: 14,195,856
effective search space: 6075826368
effective search space used: 6075826368
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.