BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo sapiens] (665 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 1311 0.0 gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 1221 0.0 gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 993 0.0 gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 114 2e-25 gi|27262638 sperm associated antigen 1 [Homo sapiens] 109 7e-24 gi|27262636 sperm associated antigen 1 [Homo sapiens] 109 7e-24 gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 103 7e-22 gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 96 1e-19 gi|54607135 translocase of outer mitochondrial membrane 70 homol... 93 7e-19 gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 84 5e-16 gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 82 2e-15 gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 81 4e-15 gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 79 1e-14 gi|4503729 FK506 binding protein 52 [Homo sapiens] 77 5e-14 gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 77 7e-14 gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 76 1e-13 gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 76 1e-13 gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 76 1e-13 gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 75 2e-13 gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 71 4e-12 gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 71 4e-12 gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sap... 67 5e-11 gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 67 5e-11 gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] 65 3e-10 gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] 65 3e-10 gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom... 62 2e-09 gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens] 62 2e-09 gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 61 3e-09 gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 61 3e-09 gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 61 3e-09 >gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo sapiens] Length = 665 Score = 1311 bits (3394), Expect = 0.0 Identities = 665/665 (100%), Positives = 665/665 (100%) Query: 1 MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN 60 MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN Sbjct: 1 MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN 60 Query: 61 FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE 120 FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE Sbjct: 61 FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE 120 Query: 121 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL Sbjct: 121 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180 Query: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE Sbjct: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240 Query: 241 LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER 300 LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER Sbjct: 241 LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER 300 Query: 301 AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR 360 AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR Sbjct: 301 AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR 360 Query: 361 TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPI 420 TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPI Sbjct: 361 TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPI 420 Query: 421 DNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNS 480 DNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNS Sbjct: 421 DNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNS 480 Query: 481 SQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATT 540 SQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATT Sbjct: 481 SQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATT 540 Query: 541 VLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHD 600 VLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHD Sbjct: 541 VLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHD 600 Query: 601 FYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELK 660 FYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELK Sbjct: 601 FYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELK 660 Query: 661 KRYGG 665 KRYGG Sbjct: 661 KRYGG 665 >gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo sapiens] Length = 631 Score = 1221 bits (3159), Expect = 0.0 Identities = 631/665 (94%), Positives = 631/665 (94%), Gaps = 34/665 (5%) Query: 1 MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN 60 MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN Sbjct: 1 MTSANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKDMELRRQNGVPEENLPPIRNGN 60 Query: 61 FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE 120 FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE Sbjct: 61 FRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESE 120 Query: 121 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL Sbjct: 121 SEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL 180 Query: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE Sbjct: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240 Query: 241 LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER 300 LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER Sbjct: 241 LRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYER 300 Query: 301 AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR 360 AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR Sbjct: 301 AIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTAR 360 Query: 361 TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPI 420 TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK Sbjct: 361 TFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK------------------------- 395 Query: 421 DNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNS 480 KPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNS Sbjct: 396 ---------KPLKKVIIEETGNLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNS 446 Query: 481 SQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATT 540 SQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATT Sbjct: 447 SQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVCQSYSEKMPIEIEQKPAQFATT 506 Query: 541 VLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHD 600 VLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHD Sbjct: 507 VLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYPKLFQKNLDPDVFNQIVKILHD 566 Query: 601 FYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELK 660 FYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELK Sbjct: 567 FYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIARALFNHIDKSGLKDSSVEELK 626 Query: 661 KRYGG 665 KRYGG Sbjct: 627 KRYGG 631 >gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo sapiens] Length = 506 Score = 993 bits (2568), Expect = 0.0 Identities = 506/506 (100%), Positives = 506/506 (100%) Query: 160 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 219 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE Sbjct: 1 MDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE 60 Query: 220 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 279 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK Sbjct: 61 AKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNK 120 Query: 280 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 339 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC Sbjct: 121 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 180 Query: 340 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 399 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE Sbjct: 181 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240 Query: 400 KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE 459 KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE Sbjct: 241 KGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVPDSTTAAAPE 300 Query: 460 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC 519 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC Sbjct: 301 NNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEEVSDTSSLQPQASLKQDVC 360 Query: 520 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP 579 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP Sbjct: 361 QSYSEKMPIEIEQKPAQFATTVLPPIPANSFQLESDFRQLKSSPDMLYQYLKQIEPSLYP 420 Query: 580 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA 639 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA Sbjct: 421 KLFQKNLDPDVFNQIVKILHDFYIEKEKPLLIFEILQRLSELKRFDMAVMFMSETEKKIA 480 Query: 640 RALFNHIDKSGLKDSSVEELKKRYGG 665 RALFNHIDKSGLKDSSVEELKKRYGG Sbjct: 481 RALFNHIDKSGLKDSSVEELKKRYGG 506 Score = 134 bits (337), Expect = 3e-31 Identities = 66/136 (48%), Positives = 93/136 (68%) Query: 116 SQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRAS 175 S E E ++ + Q+A+ K++GN +FK+GKY+ AI+CYT+G+ AD N +LP NRA Sbjct: 106 STEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAM 165 Query: 176 AYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNF 235 AY +++K+ AE DC A+ L+ SY+KA++RRG AR L KL EAK+D+E VL LEP N Sbjct: 166 AYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNK 225 Query: 236 EATNELRKISQALASK 251 +A EL KI + L K Sbjct: 226 QAVTELSKIKKELIEK 241 >gi|21361356 translocase of outer mitochondrial membrane 34 [Homo sapiens] Length = 309 Score = 114 bits (286), Expect = 2e-25 Identities = 85/297 (28%), Positives = 137/297 (46%), Gaps = 35/297 (11%) Query: 136 LKEKGNKYFKQGKYDEAIDCYTKGM-------DADPYNP-VLPTNRASAYFRLKKFAVAE 187 L+ GN+ F+ G+Y EA Y + + +DP VL +NRA+ + + Sbjct: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCI 71 Query: 188 SDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQA 247 DC A+AL K RR +A AL+K A DY+ VL+++ N A + ++++A Sbjct: 72 KDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRA 131 Query: 248 LAS----------------------KENSYPKE-----ADIVIKSTEGERKQIEAQQNKQ 280 L + NS P E A K T + ++ + + + Sbjct: 132 LMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVE 191 Query: 281 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCT 340 +A K+ GN K+G +++AIE Y+ + + +NRA+ YL +++Y EA KDCT Sbjct: 192 KARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCT 251 Query: 341 QAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 397 +A+ LDG KAF RR A L + D +L +EP N A ++K+ L Sbjct: 252 EALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNL 308 Score = 71.6 bits (174), Expect = 2e-12 Identities = 40/120 (33%), Positives = 65/120 (54%) Query: 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAES 188 D +KA VLKE+GN+ K+G + +AI+ Y++ + +NRA Y LK++ A Sbjct: 189 DVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVK 248 Query: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248 DC A+ L+ KA+ RR A AL+ + + D +L++EP N A +++ Q L Sbjct: 249 DCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNL 308 Score = 50.4 bits (119), Expect = 5e-06 Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 8/119 (6%) Query: 289 GNGFFKEGKYERAIECYTRGIA---ADGAN-----ALLPANRAMAYLKIQKYEEAEKDCT 340 GN F+ G+Y A Y R + A G++ ++L +NRA +LK + KDCT Sbjct: 16 GNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCT 75 Query: 341 QAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 399 A+ L K RR +A L K A D++TVL ++ AV ++++ + L++ Sbjct: 76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMD 134 >gi|27262638 sperm associated antigen 1 [Homo sapiens] Length = 926 Score = 109 bits (273), Expect = 7e-24 Identities = 117/499 (23%), Positives = 209/499 (41%), Gaps = 47/499 (9%) Query: 55 PIRNGNFRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHES 114 P GN +KK GKA+ + R + + EA A D+ ++ + Sbjct: 379 PCVMGNIQKKLTGKAEGGKRPARGAPQRGQTP----EAGA--------DKRSPRRASAAA 426 Query: 115 LSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTK--------GMDADPYN 166 + + G ++ LK +GN+ F+ G++ EA Y+ G + Sbjct: 427 AAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDL 486 Query: 167 PVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYER 226 +L +NRA+ Y + + DCN A+ L+ K RR A L++ +A DY+ Sbjct: 487 SILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKT 546 Query: 227 VLELEPNNFEATNELRKISQALASKENSYPKE---------ADIVIKSTEGERKQIEAQ- 276 VL+++ A + + ++S+ L + +E A + +++ ++ I Q Sbjct: 547 VLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWHPAKEMISKQA 606 Query: 277 ----QNKQQAISE-------KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMA 325 ++QQ I++ K+ GN + Y+ A+ Y+ + + + NRA+ Sbjct: 607 GDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALC 666 Query: 326 YLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQ 385 YLK+ ++EEA++DC QA+ L KAF RR A L ++ D V+LL+P + Sbjct: 667 YLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIE 726 Query: 386 AVTELSKIKKELIEKGHWDDVFLDSTQR----QNVVKPIDNPPHPGSTKPLKKVIIEETG 441 A EL ++ + L K + +R Q V + + P P + + E+ G Sbjct: 727 AKMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCLASEKGG 786 Query: 442 NLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEE 501 ++ + P+ A P NN +I A T K + L T+ L + Sbjct: 787 KSSRSPEDPEKLPIAKP-NNAYEFGQIINALSTRKDKEACAHLLAITAPKDLPMFLSNKL 845 Query: 502 VSDTSSLQPQASLKQDVCQ 520 DT L Q SLK ++ + Sbjct: 846 EGDTFLLLIQ-SLKNNLIE 863 Score = 102 bits (255), Expect = 9e-22 Identities = 82/284 (28%), Positives = 134/284 (47%), Gaps = 29/284 (10%) Query: 18 AEELQDFMRDLENWEKDIKQKD--MELRRQNGVP--EENLPPIRNGNFRKKKKGKAKESS 73 AEE + D+++W +IK+++ M P ++NLPP+R N GK K S Sbjct: 89 AEEWEKIDGDIKSWVSEIKKEEDKMHFHETETFPAMKDNLPPVRGSN-SCLHVGKEKYSK 147 Query: 74 KKTREENTKNRIKSYDYEAWAKLDVDRILDELDKD-------DSTHESLSQESESEEDGI 126 + T+++ + DY W K DV++ ++D+D D +H S E+ + G+ Sbjct: 148 RPTKKKTPR------DYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLS-KIETRIDTAGL 200 Query: 127 HVDSQKALVL--KEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184 + L KEKGN+ F G Y+EA+ YT+ + A P V NRA A +L+ + Sbjct: 201 TEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALP-TVVAYNNRAQAEIKLQNWN 259 Query: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 244 A DC + L KA RR KL EA +D +VL++EP+N A L ++ Sbjct: 260 SAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEV 319 Query: 245 SQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDR 288 + L + E + + T+G+R I+ +N + + R Sbjct: 320 ERDLKNSEAASETQ-------TKGKRMVIQEIENSEDEEGKSGR 356 Score = 76.6 bits (187), Expect = 7e-14 Identities = 52/167 (31%), Positives = 82/167 (49%), Gaps = 3/167 (1%) Query: 231 EPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGN 290 E + F+ E KI + KE + ++ + T + + ++ A EK++GN Sbjct: 160 EWDKFDVEKECLKIDEDY--KEKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGN 217 Query: 291 GFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYS 350 F G YE A+ YTR I+A + NRA A +K+Q + A +DC + + L+ Sbjct: 218 EAFNSGDYEEAVMYYTRSISAL-PTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNV 276 Query: 351 KAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 397 KA RR T KL EA +D VL +EP N A LS+++++L Sbjct: 277 KALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDL 323 >gi|27262636 sperm associated antigen 1 [Homo sapiens] Length = 926 Score = 109 bits (273), Expect = 7e-24 Identities = 117/499 (23%), Positives = 209/499 (41%), Gaps = 47/499 (9%) Query: 55 PIRNGNFRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHES 114 P GN +KK GKA+ + R + + EA A D+ ++ + Sbjct: 379 PCVMGNIQKKLTGKAEGGKRPARGAPQRGQTP----EAGA--------DKRSPRRASAAA 426 Query: 115 LSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTK--------GMDADPYN 166 + + G ++ LK +GN+ F+ G++ EA Y+ G + Sbjct: 427 AAGGGATGHPGGGQGAENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDL 486 Query: 167 PVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYER 226 +L +NRA+ Y + + DCN A+ L+ K RR A L++ +A DY+ Sbjct: 487 SILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKT 546 Query: 227 VLELEPNNFEATNELRKISQALASKENSYPKE---------ADIVIKSTEGERKQIEAQ- 276 VL+++ A + + ++S+ L + +E A + +++ ++ I Q Sbjct: 547 VLQIDCGLQLANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQAWHPAKEMISKQA 606 Query: 277 ----QNKQQAISE-------KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMA 325 ++QQ I++ K+ GN + Y+ A+ Y+ + + + NRA+ Sbjct: 607 GDSSSHRQQGITDEKTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALC 666 Query: 326 YLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQ 385 YLK+ ++EEA++DC QA+ L KAF RR A L ++ D V+LL+P + Sbjct: 667 YLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIE 726 Query: 386 AVTELSKIKKELIEKGHWDDVFLDSTQR----QNVVKPIDNPPHPGSTKPLKKVIIEETG 441 A EL ++ + L K + +R Q V + + P P + + E+ G Sbjct: 727 AKMELEEVTRLLNLKDKTAPFNKEKERRKIEIQEVNEGKEEPGRPAGEVSMGCLASEKGG 786 Query: 442 NLIQTIDVPDSTTAAAPENNPINLANVIAATGTTSKKNSSQDDLFPTSDTPRAKVLKIEE 501 ++ + P+ A P NN +I A T K + L T+ L + Sbjct: 787 KSSRSPEDPEKLPIAKP-NNAYEFGQIINALSTRKDKEACAHLLAITAPKDLPMFLSNKL 845 Query: 502 VSDTSSLQPQASLKQDVCQ 520 DT L Q SLK ++ + Sbjct: 846 EGDTFLLLIQ-SLKNNLIE 863 Score = 102 bits (255), Expect = 9e-22 Identities = 82/284 (28%), Positives = 134/284 (47%), Gaps = 29/284 (10%) Query: 18 AEELQDFMRDLENWEKDIKQKD--MELRRQNGVP--EENLPPIRNGNFRKKKKGKAKESS 73 AEE + D+++W +IK+++ M P ++NLPP+R N GK K S Sbjct: 89 AEEWEKIDGDIKSWVSEIKKEEDKMHFHETETFPAMKDNLPPVRGSN-SCLHVGKEKYSK 147 Query: 74 KKTREENTKNRIKSYDYEAWAKLDVDRILDELDKD-------DSTHESLSQESESEEDGI 126 + T+++ + DY W K DV++ ++D+D D +H S E+ + G+ Sbjct: 148 RPTKKKTPR------DYAEWDKFDVEKECLKIDEDYKEKTVIDKSHLS-KIETRIDTAGL 200 Query: 127 HVDSQKALVL--KEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184 + L KEKGN+ F G Y+EA+ YT+ + A P V NRA A +L+ + Sbjct: 201 TEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALP-TVVAYNNRAQAEIKLQNWN 259 Query: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 244 A DC + L KA RR KL EA +D +VL++EP+N A L ++ Sbjct: 260 SAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEV 319 Query: 245 SQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDR 288 + L + E + + T+G+R I+ +N + + R Sbjct: 320 ERDLKNSEAASETQ-------TKGKRMVIQEIENSEDEEGKSGR 356 Score = 76.6 bits (187), Expect = 7e-14 Identities = 52/167 (31%), Positives = 82/167 (49%), Gaps = 3/167 (1%) Query: 231 EPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGN 290 E + F+ E KI + KE + ++ + T + + ++ A EK++GN Sbjct: 160 EWDKFDVEKECLKIDEDY--KEKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGN 217 Query: 291 GFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYS 350 F G YE A+ YTR I+A + NRA A +K+Q + A +DC + + L+ Sbjct: 218 EAFNSGDYEEAVMYYTRSISAL-PTVVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNV 276 Query: 351 KAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 397 KA RR T KL EA +D VL +EP N A LS+++++L Sbjct: 277 KALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDL 323 >gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein) [Homo sapiens] Length = 543 Score = 103 bits (256), Expect = 7e-22 Identities = 77/274 (28%), Positives = 130/274 (47%), Gaps = 28/274 (10%) Query: 120 ESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFR 179 E E+ + + ++AL KE GN +K+ +D A+ Y K + DP N TN+A+ YF Sbjct: 212 EPMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFE 271 Query: 180 LKKFAVAESDCNLAVALN-------RSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232 + C A+ + R KAY+R G + F +K ++A Y + L Sbjct: 272 KGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSLA--- 328 Query: 233 NNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGF 292 + L+K Q A+ ++K E ER A N A+ EK++GN Sbjct: 329 -EHRTPDVLKKCQQ------------AEKILK--EQERL---AYINPDLALEEKNKGNEC 370 Query: 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352 F++G Y +A++ YT I + +A L +NRA Y K+ +++ A KDC + I L+ ++ K Sbjct: 371 FQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKG 430 Query: 353 FARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 386 + R+ A + +A ++ L L+ K+A Sbjct: 431 YTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEA 464 Score = 83.2 bits (204), Expect = 7e-16 Identities = 57/163 (34%), Positives = 83/163 (50%), Gaps = 12/163 (7%) Query: 136 LKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVA 195 LKEKGNK G D+A+ CY++ + DP+N VL +NR++AY + + A D V Sbjct: 7 LKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVD 66 Query: 196 LNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE--- 252 L + K YSR+ AA L + EEAK+ YE L+ E NN + L+ + LA ++ Sbjct: 67 LKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERKFMN 126 Query: 253 -----NSYPK-EAD---IVIKSTEGERKQIEAQQNKQQAISEK 286 N Y K E+D + S R+ IE +NK + K Sbjct: 127 PFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTK 169 Score = 82.4 bits (202), Expect = 1e-15 Identities = 68/262 (25%), Positives = 128/262 (48%), Gaps = 29/262 (11%) Query: 33 KDIKQKDMELRRQNGVPEENLPPIRNGNFRKKKKGKAKESSKKTREENTKNRIKSYDYEA 92 +++ +K +E+ R+N ++R+ K A+ + +EE K+ I Y+ Sbjct: 279 RELCEKAIEVGREN-----------REDYRQIAKAYARIGNSYFKEEKYKDAIHFYN--- 324 Query: 93 WAKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEA 152 L R D L K + L ++ E +++ AL K KGN+ F++G Y +A Sbjct: 325 -KSLAEHRTPDVLKKCQQAEKILKEQ----ERLAYINPDLALEEKNKGNECFQKGDYPQA 379 Query: 153 IDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARF 212 + YT+ + +P + L +NRA+ Y +L +F +A DC + L ++ K Y+R+ AA Sbjct: 380 MKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQLEPTFIKGYTRKAAALE 439 Query: 213 ALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE------ADIVIK-- 264 A++ +A Y++ L+L+ + EA + ++ A ++ +S P++ AD ++ Sbjct: 440 AMKDYTKAMDVYQKALDLDSSCKEAADGYQRCMMAQYNRHDS-PEDVKRRAMADPEVQQI 498 Query: 265 -STEGERKQIEAQQNKQQAISE 285 S R +E Q QA+SE Sbjct: 499 MSDPAMRLILEQMQKDPQALSE 520 Score = 70.9 bits (172), Expect = 4e-12 Identities = 44/165 (26%), Positives = 81/165 (49%), Gaps = 7/165 (4%) Query: 280 QQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDC 339 +Q K++GN G + A++CY+ I D N +L +NR+ AY K Y++A +D Sbjct: 2 EQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDG 61 Query: 340 TQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 399 + + L + K ++R+ A FL + EAK+ +E L E N Q L ++ L E Sbjct: 62 CKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAE 121 Query: 400 KGHWDDVFLDSTQRQNVVKPIDNPPHPGS--TKPLKKVIIEETGN 442 + F++ N+ + +++ P + + P + +IE+ N Sbjct: 122 R-----KFMNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRN 161 Score = 50.4 bits (119), Expect = 5e-06 Identities = 64/283 (22%), Positives = 109/283 (38%), Gaps = 49/283 (17%) Query: 124 DGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKF 183 + I +D ++ + Y K+G Y +A + K +D P + +A+A L +F Sbjct: 29 EAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRF 88 Query: 184 AVAES--DCNLAVALNRSYTKAYSRRGAARFA-------------LQKLEEAKKDYERVL 228 A+ + L N K + AR A QKLE + R L Sbjct: 89 EEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERKFMNPFNMPNLYQKLESDPRT--RTL 146 Query: 229 ELEPNNFEATNELRKISQALASKEN-----------------SYPKEADIVI-------- 263 +P E +LR L +K S +E +I Sbjct: 147 LSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPK 206 Query: 264 KSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRA 323 K T+ E + + +NK+QA+ EK+ GN +K+ ++ A++ Y + D N N+A Sbjct: 207 KETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQA 266 Query: 324 MAYLKIQKYEEAEKDCTQAILLD-------GSYSKAFARRGTA 359 Y + Y + + C +AI + +KA+AR G + Sbjct: 267 AVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYARIGNS 309 >gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta [Homo sapiens] Length = 304 Score = 95.9 bits (237), Expect = 1e-19 Identities = 49/120 (40%), Positives = 70/120 (58%) Query: 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAES 188 D KA LK++GN + K+ Y A+DCYT+ ++ DP N V NRA+A +L + A Sbjct: 81 DVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIK 140 Query: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248 DC A+A++ Y+KAY R G A AL K EEA Y++ L+L+P N + L+ Q L Sbjct: 141 DCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKL 200 Score = 88.6 bits (218), Expect = 2e-17 Identities = 47/114 (41%), Positives = 63/114 (55%) Query: 286 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 345 KD GN KE Y A++CYT+ I D NA+ NRA A K+ Y +A KDC +AI + Sbjct: 89 KDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAI 148 Query: 346 DGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 399 D YSKA+ R G A T L K EA ++ L L+P N + L +++L E Sbjct: 149 DSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202 Score = 32.3 bits (72), Expect = 1.4 Identities = 30/117 (25%), Positives = 54/117 (46%), Gaps = 15/117 (12%) Query: 78 EENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESE----EDGIHVDSQKA 133 ++ N +K +Y A I ELD +++ + ++S+ D I D +KA Sbjct: 89 KDEGNNHMKEENYAAAVDCYTQAI--ELDPNNAVYYCNRAAAQSKLGHYTDAIK-DCEKA 145 Query: 134 LVLKEKGNK-YFKQG-------KYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182 + + K +K Y + G K++EA+ Y K +D DP N +N A +L++ Sbjct: 146 IAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIAEQKLRE 202 >gi|54607135 translocase of outer mitochondrial membrane 70 homolog A [Homo sapiens] Length = 608 Score = 93.2 bits (230), Expect = 7e-19 Identities = 83/281 (29%), Positives = 121/281 (43%), Gaps = 37/281 (13%) Query: 122 EEDGIHVDSQ---KALVLKEKGNKYFKQGKYDEAIDCYTKGMDADP--YNPVLPT---NR 173 E G H+D +A K KGNKYFK GKY++AI CYT+ + P N L T NR Sbjct: 100 EGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNR 159 Query: 174 ASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPN 233 A+A+ +L+K+ DC AV LN Y KA RR A L +E +D V LE Sbjct: 160 AAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILE-- 217 Query: 234 NFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFF 293 F+ + S LA K + G+ K E +N++ + +F Sbjct: 218 GFQ-----NQQSMLLADK-----------VLKLLGKEKAKEKYKNREPLMPSPQFIKSYF 261 Query: 294 KEGKYERAIECYTRGIAA----DGANALLPANRAMAYLKIQKYEEAE------KDCTQAI 343 + + +G + D L YLK ++Y E E +C++ I Sbjct: 262 SSFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISECSKEI 321 Query: 344 LLDGSY-SKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383 +G Y ++A R T +G N AK D + V+ L+ N Sbjct: 322 DAEGKYMAEALLLRATFYLLIGNANAAKPDLDKVISLKEAN 362 Score = 75.5 bits (184), Expect = 1e-13 Identities = 45/123 (36%), Positives = 69/123 (56%), Gaps = 6/123 (4%) Query: 281 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGAN-----ALLPANRAMAYLKIQKYEEA 335 +A + K++GN +FK GKYE+AI+CYT I+ + NRA A+ ++QK++E Sbjct: 113 RAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWKEV 172 Query: 336 EKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEP-GNKQAVTELSKIK 394 +DCT+A+ L+ Y KA RR A L E +D V +LE N+Q++ K+ Sbjct: 173 AQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEGFQNQQSMLLADKVL 232 Query: 395 KEL 397 K L Sbjct: 233 KLL 235 Score = 40.8 bits (94), Expect = 0.004 Identities = 56/286 (19%), Positives = 108/286 (37%), Gaps = 31/286 (10%) Query: 108 DDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNP 167 ++ ++ + E E D +AL+L+ Y G + A K + N Sbjct: 306 EEENYDKIISECSKEIDAEGKYMAEALLLR--ATFYLLIGNANAAKPDLDKVISLKEANV 363 Query: 168 VLPTN----RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKD 223 L N R S Y + ++ ++ D N+A ++ Y RG + L ++EEA D Sbjct: 364 KLRANALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVAD 423 Query: 224 YERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI 283 ++ + L P + L + + A +Y T QI+A + + Sbjct: 424 FDECIRLRPE-----SALAQAQKCFALYRQAY----------TGNNSSQIQAAMKGFEEV 468 Query: 284 SEK----DRGNGFFKEG-----KYERAIECYTRGIAADGANALLPANRAMAYLK-IQKYE 333 +K G + + ++ +A E Y + I + NA ++ + L+ Q + Sbjct: 469 IKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLD 528 Query: 334 EAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLL 379 + ++AI +D A+ GT G + +A F + L Sbjct: 529 RGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINL 574 >gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1 [Homo sapiens] Length = 494 Score = 83.6 bits (205), Expect = 5e-16 Identities = 87/355 (24%), Positives = 135/355 (38%), Gaps = 89/355 (25%) Query: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVA---- 186 ++A KE+GN Y+ + Y+EA + YTK +D P N NRA+ L +F A Sbjct: 26 REAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDA 85 Query: 187 ----------------ESDCNL----AVALNRSYTKAYSRRGAARFALQKLEEAKK--DY 224 E C+L A+A RS+ +A A Q+ + A +Y Sbjct: 86 QQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVMEY 145 Query: 225 ERVLE--LEPNNFE--------------ATNELRKISQALASKENSYPKEADIV------ 262 E++ E E +F A + + + + YP+ + Sbjct: 146 EKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRM 205 Query: 263 -------------------------------IKSTEGERKQIEAQQNKQQAISEKDRGNG 291 ++ K A +N + ++K+ GN Sbjct: 206 DSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALKAKKEDGNK 265 Query: 292 FFKEGKYERAIECYTRGIAADG----ANALLPANRAMAYLKIQKYEEAEKDCTQAILLDG 347 FKEG Y+ A E YT + D NA L NR K++K ++A +DCT A+ LD Sbjct: 266 AFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDD 325 Query: 348 SYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN------KQAVTELSKIKKE 396 +Y KA+ RR + EA +D+E V E K A EL K K++ Sbjct: 326 TYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKRK 380 Score = 75.9 bits (185), Expect = 1e-13 Identities = 64/198 (32%), Positives = 91/198 (45%), Gaps = 20/198 (10%) Query: 113 ESLSQESESEEDGIHVDSQKAL-VLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN----P 167 ++L + E+ I + KAL KE GNK FK+G Y A + YT+ + DP N Sbjct: 235 QALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNA 294 Query: 168 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 227 L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE+V Sbjct: 295 KLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKV 354 Query: 228 LELEPNN------FEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQ 281 + E A ELRK SK Y K + ++E E I+ K+ Sbjct: 355 YQTEKTKEHKQLLKNAQLELRK------SKRKDYYKILGVDKNASEDE---IKKAYRKRA 405 Query: 282 AISEKDRGNGFFKEGKYE 299 + DR +G E + E Sbjct: 406 LMHHPDRHSGASAEVQKE 423 Score = 68.2 bits (165), Expect = 2e-11 Identities = 41/132 (31%), Positives = 67/132 (50%), Gaps = 2/132 (1%) Query: 258 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 317 E D+V+ +TE E ++ Q+ K++A + K++GN ++ + Y A YT+ I NA Sbjct: 6 ECDVVMAATEPEL--LDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNAS 63 Query: 318 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 377 NRA + + ++ EA D Q++ LD S+ + R G LG A + F+ L Sbjct: 64 YYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRAL 123 Query: 378 LLEPGNKQAVTE 389 L+ N QA E Sbjct: 124 ELDHKNAQAQQE 135 >gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] Length = 499 Score = 81.6 bits (200), Expect = 2e-15 Identities = 48/155 (30%), Positives = 84/155 (54%), Gaps = 1/155 (0%) Query: 267 EGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAY 326 E R + A ++A K + N +FK YE AI+ Y++ I + +NA+ NR++AY Sbjct: 13 EPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAY 72 Query: 327 LKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 386 L+ + Y A D T+AI LD Y K + RR + LGK A +D+ETV+ ++P +K A Sbjct: 73 LRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDA 132 Query: 387 VTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPID 421 + + K ++++ ++ +++VV +D Sbjct: 133 KMKYQECNK-IVKQKAFERAIAGDEHKRSVVDSLD 166 Score = 78.6 bits (192), Expect = 2e-14 Identities = 39/121 (32%), Positives = 70/121 (57%) Query: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDC 190 ++A LK + N YFK Y+ AI Y++ ++ +P N + NR+ AY R + + A D Sbjct: 26 KRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDA 85 Query: 191 NLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALAS 250 A+ L++ Y K Y RR A+ AL K A +DYE V++++P++ +A + ++ ++ + Sbjct: 86 TRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQ 145 Query: 251 K 251 K Sbjct: 146 K 146 >gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] Length = 313 Score = 80.9 bits (198), Expect = 4e-15 Identities = 48/141 (34%), Positives = 79/141 (56%), Gaps = 2/141 (1%) Query: 96 LDVDRILDELDKDDSTHESLSQE--SESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAI 153 L + + L E+ + +T + + Q+ S + DS +A LK +GN+ K ++ A+ Sbjct: 52 LALPQTLPEIFEAAATGKEMPQDLRSPARTPPSEEDSAEAERLKTEGNEQMKVENFEAAV 111 Query: 154 DCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFA 213 Y K ++ +P N V NRA+AY +L +A A DC A+ ++ +Y+KAY R G A + Sbjct: 112 HFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSKAYGRMGLALSS 171 Query: 214 LQKLEEAKKDYERVLELEPNN 234 L K EA Y++ LEL+P+N Sbjct: 172 LNKHVEAVAYYKKALELDPDN 192 Score = 76.3 bits (186), Expect = 9e-14 Identities = 56/168 (33%), Positives = 80/168 (47%), Gaps = 18/168 (10%) Query: 232 PNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNG 291 P FEA +++ Q L S + P E D S E ER + E GN Sbjct: 59 PEIFEAAATGKEMPQDLRSPARTPPSEED----SAEAERLKTE--------------GNE 100 Query: 292 FFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSK 351 K +E A+ Y + I + ANA+ NRA AY K+ Y A +DC +AI +D +YSK Sbjct: 101 QMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDCERAICIDPAYSK 160 Query: 352 AFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 399 A+ R G A + L K EA ++ L L+P N+ + L + +L E Sbjct: 161 AYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYKSNLKIAELKLRE 208 >gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] Length = 705 Score = 79.3 bits (194), Expect = 1e-14 Identities = 72/295 (24%), Positives = 143/295 (48%), Gaps = 34/295 (11%) Query: 4 ANKAIELQLQVKQNAEELQDFMRDLENWEKDIKQKD-MELRRQNGVPEENLPPIRNGNFR 62 A+K +LQ +K N +E+ + ++++ + + ++QK +E ++ + EE+ Sbjct: 3 ADKEKDLQKFLK-NVDEISNLIQEMNSDDPVVQQKAVLETEKRLLLMEED---------- 51 Query: 63 KKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESE 122 +++ + + + KT + +KS + +++ + L ++KD +E++ Sbjct: 52 -QEEDECRTTLNKTMISPPQTAMKSAE-----EINSEAFLASVEKDAKERAKRRRENKVL 105 Query: 123 EDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKK 182 D LKEKGN+ F +G Y+ AI Y++G++ VL TNRA AY +L+ Sbjct: 106 ADA----------LKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLED 155 Query: 183 FAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPN-NFEATNEL 241 + A DC A+ + TKAY G A AL+ +++ Y+++LE+ P + L Sbjct: 156 YEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQTQVKGYL 215 Query: 242 RKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEG 296 ++ L K + KEA ++ S G+ + +N + +S+ D+ F+ G Sbjct: 216 NQVD--LQEKADLQEKEAHELLDS--GKNTAV-TTKNLLETLSKPDQIPLFYAGG 265 Score = 67.8 bits (164), Expect = 3e-11 Identities = 52/197 (26%), Positives = 90/197 (45%), Gaps = 25/197 (12%) Query: 258 EADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANAL 317 EA + + + + ++NK A + K++GN F EG YE AI Y+ G+ + Sbjct: 82 EAFLASVEKDAKERAKRRRENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKV 141 Query: 318 LPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVL 377 L NRA AY+K++ YE+A DC A+ D +KA+ G A L + +++ ++ +L Sbjct: 142 LYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKIL 201 Query: 378 LLEPGNKQAVTELSKIKKELIEKGHWDDVFLD---STQRQNVVKPIDNPPHPGSTKPLKK 434 + P K + KG+ + V L Q + + +D+ + T Sbjct: 202 EINP------------KLQTQVKGYLNQVDLQEKADLQEKEAHELLDSGKNTAVT----- 244 Query: 435 VIIEETGNLIQTIDVPD 451 T NL++T+ PD Sbjct: 245 -----TKNLLETLSKPD 256 >gi|4503729 FK506 binding protein 52 [Homo sapiens] Length = 459 Score = 77.0 bits (188), Expect = 5e-14 Identities = 58/194 (29%), Positives = 101/194 (52%), Gaps = 23/194 (11%) Query: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIA------- 310 ++ +KS E ++ ++ +++ +Q+ K+RG +FKEGKY++A+ Y + ++ Sbjct: 246 ELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESS 305 Query: 311 -----ADGANALLPA---NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362 A A AL A N AM +LK+Q + A + C +A+ LD + K RRG A Sbjct: 306 FSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLA 365 Query: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELS----KIKKELI-EKGHWDDVFLDSTQRQNVV 417 + A+ DF+ VL L P NK A T+L+ +I+++L EK + ++F + +N Sbjct: 366 VNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKA 425 Query: 418 K-PIDNPPHPGSTK 430 K + HP T+ Sbjct: 426 KAEASSGDHPTDTE 439 Score = 71.6 bits (174), Expect = 2e-12 Identities = 51/178 (28%), Positives = 84/178 (47%), Gaps = 22/178 (12%) Query: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTK-------------- 158 +S + ES E +++ ++KE+G YFK+GKY +A+ Y K Sbjct: 250 KSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNE 309 Query: 159 -GMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKL 217 A N A + +L+ F+ A CN A+ L+ + K RRG A A+ Sbjct: 310 EAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDF 369 Query: 218 EEAKKDYERVLELEPNNFEATNEL----RKISQALASKENSYPKEADIVIKSTEGERK 271 E A+ D+++VL+L PNN A +L ++I + LA ++ Y A++ + E E K Sbjct: 370 ELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLY---ANMFERLAEEENK 424 >gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] Length = 292 Score = 76.6 bits (187), Expect = 7e-14 Identities = 54/194 (27%), Positives = 94/194 (48%), Gaps = 18/194 (9%) Query: 71 ESSKKTREENTKNRIKSYDYEAWAKLDVDR-ILDELDKDDSTHESLSQESESEEDGIHVD 129 + S EE +++++ E ++D L EL+K+ S E + ES Sbjct: 65 DCSASFEEEPGADKVENKSNEDVNSSELDEEYLIELEKNMSDEEKQKRREESTR------ 118 Query: 130 SQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPY-----NPVLPTNRASAYFRLKKFA 184 LKE+GN+ FK+G Y EA Y++ ++ P +L +NRA+A + K Sbjct: 119 ------LKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKE 172 Query: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 244 +A +DC+ A+ LN SY +A RR KL+EA +DY+ +LE +P+ +A ++ Sbjct: 173 MAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRL 232 Query: 245 SQALASKENSYPKE 258 + + + +E Sbjct: 233 PKQIEERNERLKEE 246 Score = 69.7 bits (169), Expect = 8e-12 Identities = 49/172 (28%), Positives = 84/172 (48%), Gaps = 6/172 (3%) Query: 234 NFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFF 293 +FE K+ NS + + +I+ E E Q+ ++++ K+ GN F Sbjct: 69 SFEEEPGADKVENKSNEDVNSSELDEEYLIE-LEKNMSDEEKQKRREESTRLKEEGNEQF 127 Query: 294 KEGKYERAIECYTRGIAA-----DGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGS 348 K+G Y A Y+R + ++L +NRA A +K K E A DC++AI L+ S Sbjct: 128 KKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEMAINDCSKAIQLNPS 187 Query: 349 YSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEK 400 Y +A RR KL+EA +D++++L +P QA ++ K++ E+ Sbjct: 188 YIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEER 239 >gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] Length = 457 Score = 75.9 bits (185), Expect = 1e-13 Identities = 51/162 (31%), Positives = 87/162 (53%), Gaps = 17/162 (10%) Query: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308 ++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G Sbjct: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303 Query: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362 ++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+ Sbjct: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363 Query: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWD 404 + + AK DFE VL + P NK A ++S +K+ E D Sbjct: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 405 Score = 68.2 bits (165), Expect = 2e-11 Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 19/192 (9%) Query: 111 THESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMD--------- 161 T +S + ES E ++A ++KEKG YFK GKY +A+ Y K + Sbjct: 246 TLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLS 305 Query: 162 ------ADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215 ++ + N A Y +L+++ A C+ A+ L+ + K RRG A+ + Sbjct: 306 EKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365 Query: 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQI 273 + E AK D+E+VLE+ P N A ++ + Q A + N + A++ K E + K+ Sbjct: 366 EFESAKGDFEKVLEVNPQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE- 423 Query: 274 EAQQNKQQAISE 285 EA + + SE Sbjct: 424 EANKAMGKKTSE 435 >gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] Length = 457 Score = 75.9 bits (185), Expect = 1e-13 Identities = 51/162 (31%), Positives = 87/162 (53%), Gaps = 17/162 (10%) Query: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308 ++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G Sbjct: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303 Query: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362 ++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+ Sbjct: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363 Query: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWD 404 + + AK DFE VL + P NK A ++S +K+ E D Sbjct: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 405 Score = 68.2 bits (165), Expect = 2e-11 Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 19/192 (9%) Query: 111 THESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMD--------- 161 T +S + ES E ++A ++KEKG YFK GKY +A+ Y K + Sbjct: 246 TLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLS 305 Query: 162 ------ADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215 ++ + N A Y +L+++ A C+ A+ L+ + K RRG A+ + Sbjct: 306 EKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365 Query: 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQI 273 + E AK D+E+VLE+ P N A ++ + Q A + N + A++ K E + K+ Sbjct: 366 EFESAKGDFEKVLEVNPQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE- 423 Query: 274 EAQQNKQQAISE 285 EA + + SE Sbjct: 424 EANKAMGKKTSE 435 >gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] Length = 457 Score = 75.9 bits (185), Expect = 1e-13 Identities = 51/162 (31%), Positives = 87/162 (53%), Gaps = 17/162 (10%) Query: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308 ++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G Sbjct: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303 Query: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362 ++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+ Sbjct: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363 Query: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWD 404 + + AK DFE VL + P NK A ++S +K+ E D Sbjct: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 405 Score = 68.2 bits (165), Expect = 2e-11 Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 19/192 (9%) Query: 111 THESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMD--------- 161 T +S + ES E ++A ++KEKG YFK GKY +A+ Y K + Sbjct: 246 TLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLS 305 Query: 162 ------ADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215 ++ + N A Y +L+++ A C+ A+ L+ + K RRG A+ + Sbjct: 306 EKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365 Query: 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQI 273 + E AK D+E+VLE+ P N A ++ + Q A + N + A++ K E + K+ Sbjct: 366 EFESAKGDFEKVLEVNPQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE- 423 Query: 274 EAQQNKQQAISE 285 EA + + SE Sbjct: 424 EANKAMGKKTSE 435 >gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2 [Homo sapiens] Length = 438 Score = 75.1 bits (183), Expect = 2e-13 Identities = 62/194 (31%), Positives = 92/194 (47%), Gaps = 12/194 (6%) Query: 113 ESLSQESESEEDGIHVDSQKAL-VLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN----P 167 ++L + E+ I + KAL KE GNK FK+G Y A + YT+ + DP N Sbjct: 179 QALRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNA 238 Query: 168 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 227 L NR + +L+K A DC AV L+ +Y KAY RR ++ EEA +DYE+V Sbjct: 239 KLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKV 298 Query: 228 LELEPNNFEATNELRKISQ--ALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISE 285 + E + +L K +Q SK Y K + ++E E I+ K+ + Sbjct: 299 YQTEKT--KEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDE---IKKAYRKRALMHH 353 Query: 286 KDRGNGFFKEGKYE 299 DR +G E + E Sbjct: 354 PDRHSGASAEVQKE 367 Score = 70.9 bits (172), Expect = 4e-12 Identities = 47/144 (32%), Positives = 69/144 (47%), Gaps = 10/144 (6%) Query: 263 IKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADG----ANALL 318 ++ K A +N + ++K+ GN FKEG Y+ A E YT + D NA L Sbjct: 181 LRMAPDHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKL 240 Query: 319 PANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLL 378 NR K++K ++A +DCT A+ LD +Y KA+ RR + EA +D+E V Sbjct: 241 YCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ 300 Query: 379 LEPGN------KQAVTELSKIKKE 396 E K A EL K K++ Sbjct: 301 TEKTKEHKQLLKNAQLELKKSKRK 324 Score = 48.9 bits (115), Expect = 1e-05 Identities = 44/223 (19%), Positives = 85/223 (38%), Gaps = 35/223 (15%) Query: 164 PYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKD 223 P N NRA+ L +F A D +V L+ S+ + + R G +L A + Sbjct: 3 PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62 Query: 224 YERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI 283 ++R LEL+ N +A E + + + + + I Sbjct: 63 FQRALELDHKNAQAQQEFKNANAVM------------------------------EYEKI 92 Query: 284 SEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAI 343 +E D F++ + + + C R + A +A + +Y EA+ + + Sbjct: 93 AETD-----FEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDIL 147 Query: 344 LLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQA 386 +D + + A RG + + +A Q F L + P +++A Sbjct: 148 RMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKA 190 Score = 40.8 bits (94), Expect = 0.004 Identities = 24/75 (32%), Positives = 35/75 (46%) Query: 315 NALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFE 374 NA NRA + + ++ EA D Q++ LD S+ + R G LG A + F+ Sbjct: 5 NASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQ 64 Query: 375 TVLLLEPGNKQAVTE 389 L L+ N QA E Sbjct: 65 RALELDHKNAQAQQE 79 >gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo sapiens] Length = 929 Score = 70.9 bits (172), Expect = 4e-12 Identities = 43/118 (36%), Positives = 63/118 (53%), Gaps = 3/118 (2%) Query: 286 KDRGNGFFKEGKYERAIECYTRGIAADGA---NALLPANRAMAYLKIQKYEEAEKDCTQA 342 + GN FK G Y A+ YT+ + D A+L NRA +LK++ Y++AE + ++A Sbjct: 10 RKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKA 69 Query: 343 ILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEK 400 I DG KA RR A LG+L++A D + + LEP NK L I ++ EK Sbjct: 70 IEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEK 127 Score = 66.2 bits (160), Expect = 9e-11 Identities = 50/165 (30%), Positives = 81/165 (49%), Gaps = 12/165 (7%) Query: 136 LKEKGNKYFKQGKYDEAIDCYTK--GMDADPYN-PVLPTNRASAYFRLKKFAVAESDCNL 192 L+++GN+ FK G Y A+ YT+ G+DA P + VL NRA+ + +L+ + AE++ + Sbjct: 9 LRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASK 68 Query: 193 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252 A+ + KA RR A L +L++A D +R + LEP N LR I + K Sbjct: 69 AIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKV 128 Query: 253 NSYPKEADIVIKS-----TEGERKQIEAQQNKQQ---AISEKDRG 289 Y D ++ + E K E +Q Q ++ +D G Sbjct: 129 R-YMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAG 172 >gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo sapiens] Length = 944 Score = 70.9 bits (172), Expect = 4e-12 Identities = 43/118 (36%), Positives = 63/118 (53%), Gaps = 3/118 (2%) Query: 286 KDRGNGFFKEGKYERAIECYTRGIAADGA---NALLPANRAMAYLKIQKYEEAEKDCTQA 342 + GN FK G Y A+ YT+ + D A+L NRA +LK++ Y++AE + ++A Sbjct: 25 RKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASKA 84 Query: 343 ILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEK 400 I DG KA RR A LG+L++A D + + LEP NK L I ++ EK Sbjct: 85 IEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEK 142 Score = 66.2 bits (160), Expect = 9e-11 Identities = 50/165 (30%), Positives = 81/165 (49%), Gaps = 12/165 (7%) Query: 136 LKEKGNKYFKQGKYDEAIDCYTK--GMDADPYN-PVLPTNRASAYFRLKKFAVAESDCNL 192 L+++GN+ FK G Y A+ YT+ G+DA P + VL NRA+ + +L+ + AE++ + Sbjct: 24 LRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEASK 83 Query: 193 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKE 252 A+ + KA RR A L +L++A D +R + LEP N LR I + K Sbjct: 84 AIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKVFQEALRNIGGQIQEKV 143 Query: 253 NSYPKEADIVIKS-----TEGERKQIEAQQNKQQ---AISEKDRG 289 Y D ++ + E K E +Q Q ++ +D G Sbjct: 144 R-YMSSTDAKVEQMFQILLDPEEKGTEKKQKASQNLVVLAREDAG 187 >gi|5453980 DnaJ (Hsp40) homolog, subfamily C, member 3 [Homo sapiens] Length = 504 Score = 67.0 bits (162), Expect = 5e-11 Identities = 71/295 (24%), Positives = 117/295 (39%), Gaps = 44/295 (14%) Query: 120 ESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFR 179 E E G++ D +K L E G K G+ +A+ + +D DP N + RA+ + Sbjct: 27 EGAECGVNADVEKHL---ELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLA 83 Query: 180 LKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATN 239 + K A D + L +T A +RG KL+EA+ D+++VL+ P+ Sbjct: 84 MGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPS------ 137 Query: 240 ELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYE 299 EN + +IKS E Q+ + QA++ F G Y Sbjct: 138 ------------ENEEKEAQSQLIKSD-------EMQRLRSQALNA-------FGSGDYT 171 Query: 300 RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTA 359 AI + + +A L RA ++K + +A D A L ++AF + T Sbjct: 172 AAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTL 231 Query: 360 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK---------ELIEKGHWDD 405 LG + + L L+ +K+ ++KK ELI G + D Sbjct: 232 YYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTD 286 Score = 36.6 bits (83), Expect = 0.076 Identities = 56/300 (18%), Positives = 116/300 (38%), Gaps = 33/300 (11%) Query: 98 VDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYT 157 +D D+ K ++ S ++E E++ I D + L + + F G Y AI Sbjct: 121 LDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRL--RSQALNAFGSGDYTAAIAFLD 178 Query: 158 KGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKL 217 K ++ ++ L RA + + + A SD A L T+A+ + + L Sbjct: 179 KILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDH 238 Query: 218 EEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQ 277 E + + L+L+ ++ +++ K N + A+ +I+ + + +A Sbjct: 239 ELSLSEVRECLKLDQDHKRCFAHYKQVK-----KLNKLIESAEELIR----DGRYTDAT- 288 Query: 278 NKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEK 337 +K +++ + + + ER C++ K +K EA + Sbjct: 289 SKYESVMKTEPSIAEYTVRSKERICHCFS---------------------KDEKPVEAIR 327 Query: 338 DCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 397 C++ + ++ A R A +EA QD+ET ++Q L K ++ L Sbjct: 328 VCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLL 387 Score = 31.6 bits (70), Expect = 2.5 Identities = 41/198 (20%), Positives = 73/198 (36%), Gaps = 8/198 (4%) Query: 68 KAKESSKKTREENTKNRIKSYDYEAWAKLDV--DRILDELDKDDSTHESLSQESESEEDG 125 K E K + +++K+ + EA+ K+ ++ D E L + + + Sbjct: 200 KEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCF 259 Query: 126 IHVDSQKAL-VLKEKGNKYFKQGKYDEAIDCYTKGMDADP----YNPVLPTNRASAYFRL 180 H K L L E + + G+Y +A Y M +P Y + + Sbjct: 260 AHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKD 319 Query: 181 KKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNE 240 +K A C+ + + A R A + +EA +DYE E N+ + Sbjct: 320 EKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREG 379 Query: 241 LRKISQAL-ASKENSYPK 257 L K + L S++ Y K Sbjct: 380 LEKAQRLLKQSQKRDYYK 397 >gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] Length = 2481 Score = 67.0 bits (162), Expect = 5e-11 Identities = 38/120 (31%), Positives = 65/120 (54%) Query: 266 TEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMA 325 T G+R +K + + + + N +G + AI Y +A D N +L +NR+ A Sbjct: 42 TIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAA 101 Query: 326 YLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQ 385 Y+KIQ+Y++A D +A LL+ + KA+ R+G A +LG+ +A F + L +P + Q Sbjct: 102 YMKIQQYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQ 161 Score = 49.3 bits (116), Expect = 1e-05 Identities = 28/98 (28%), Positives = 50/98 (51%) Query: 139 KGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNR 198 + N+ G + AI Y + + DP N +L +NR++AY +++++ A D A LN Sbjct: 64 QSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNP 123 Query: 199 SYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFE 236 + KAY R+G A L + +A + L +P + + Sbjct: 124 KWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQ 161 Score = 36.2 bits (82), Expect = 0.100 Identities = 56/222 (25%), Positives = 89/222 (40%), Gaps = 38/222 (17%) Query: 143 YFKQGKYDEAIDCYTKGMD-----------ADPYNPVLPT-------NRASAYFRLKKFA 184 Y GKY A CY + +D A Y + T A YF + Sbjct: 804 YMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAM 863 Query: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI 244 + + N +V L+R +AY G AL EEA K YE+ L + ++ N ++ Sbjct: 864 LQQLSGNESV-LDRG--RAYGNLGDCYEALGDYEEAIKYYEQYLSVA----QSLNRMQDQ 916 Query: 245 SQALASKENSYPKEADIVIKSTEGERKQIEAQQ-----NKQQAISEKDRGNGFFKEGKYE 299 ++A N + + E++ + A + NK QA E G+ + G YE Sbjct: 917 AKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAFNKAQAYGE--LGSLHSQLGNYE 974 Query: 300 RAIECYTR--GIAADGANALLPANRAM----AYLKIQKYEEA 335 +AI C R IA D + L ++ A Y ++ +Y+ A Sbjct: 975 QAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTA 1016 >gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] Length = 929 Score = 64.7 bits (156), Expect = 3e-10 Identities = 40/123 (32%), Positives = 66/123 (53%), Gaps = 3/123 (2%) Query: 132 KALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT---NRASAYFRLKKFAVAES 188 +A+ LKE+GN++F+ Y A + Y++ + +L T NRA+ + + + A S Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64 Query: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248 D + A+ +N S KA RR A L KL++A KD +R LEP N LR+++ ++ Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124 Query: 249 ASK 251 K Sbjct: 125 QEK 127 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/123 (32%), Positives = 62/123 (50%), Gaps = 3/123 (2%) Query: 281 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPA---NRAMAYLKIQKYEEAEK 337 +A+ K+ GN F+ Y+ A Y++ + ALL NRA LK + Y +A Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64 Query: 338 DCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 397 D ++AI ++ S KA RR A LGKL++A +D + LEP N+ L ++ + Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124 Query: 398 IEK 400 EK Sbjct: 125 QEK 127 >gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] Length = 931 Score = 64.7 bits (156), Expect = 3e-10 Identities = 40/123 (32%), Positives = 66/123 (53%), Gaps = 3/123 (2%) Query: 132 KALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT---NRASAYFRLKKFAVAES 188 +A+ LKE+GN++F+ Y A + Y++ + +L T NRA+ + + + A S Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64 Query: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248 D + A+ +N S KA RR A L KL++A KD +R LEP N LR+++ ++ Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124 Query: 249 ASK 251 K Sbjct: 125 QEK 127 Score = 61.2 bits (147), Expect = 3e-09 Identities = 40/123 (32%), Positives = 62/123 (50%), Gaps = 3/123 (2%) Query: 281 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPA---NRAMAYLKIQKYEEAEK 337 +A+ K+ GN F+ Y+ A Y++ + ALL NRA LK + Y +A Sbjct: 5 EAVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAAS 64 Query: 338 DCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 397 D ++AI ++ S KA RR A LGKL++A +D + LEP N+ L ++ + Sbjct: 65 DASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124 Query: 398 IEK 400 EK Sbjct: 125 QEK 127 >gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo sapiens] Length = 420 Score = 62.0 bits (149), Expect = 2e-09 Identities = 66/265 (24%), Positives = 113/265 (42%), Gaps = 18/265 (6%) Query: 4 ANKAIELQLQVKQNAEELQDFMRD--LENWEKDIKQKDMELRRQN---GVPEENLPPIRN 58 A KA+E + ++ AEE + R+ L EK IK++ +++ ++ + NL P + Sbjct: 155 ATKALEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKSLTRNLASRNLAP-KG 213 Query: 59 GNFRKKKKGKAKESSKKTREENTKNRIKSYDYEAWAKLDVDRILDE---LDKDDSTHESL 115 N K KE S +I L ++ +E L K ++ Sbjct: 214 RNSENIFTEKLKEDSIPAPRSVGSIKINFTPRVFPTALRESQVAEEEEWLHKQAEARRAM 273 Query: 116 SQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRAS 175 + + +E + + + LK+KGNK F Y AI+ Y + + P+L NRA+ Sbjct: 274 NTDI-AELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAA 332 Query: 176 AYFRLKKFAVAESDCNLAVAL--------NRSYTKAYSRRGAARFALQKLEEAKKDYERV 227 + +LK A D + A+ L + KA+ RRG A L+ E +DYE Sbjct: 333 CHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAA 392 Query: 228 LELEPNNFEATNELRKISQALASKE 252 L+++P+N + KI + E Sbjct: 393 LKIDPSNKIVQIDAEKIRNVIQGTE 417 Score = 58.9 bits (141), Expect = 1e-08 Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 22/155 (14%) Query: 262 VIKSTEGERKQIEAQQNKQQAISE--------------KDRGNGFFKEGKYERAIECYTR 307 V + E KQ EA++ I+E KD+GN F Y AI Y Sbjct: 256 VAEEEEWLHKQAEARRAMNTDIAELCDLKEEEKNPEWLKDKGNKLFATENYLAAINAYNL 315 Query: 308 GIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL--------DGSYSKAFARRGTA 359 I + LL NRA +LK++ +A +D ++A+ L + KA RRGTA Sbjct: 316 AIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALELLMPPVTDNANARMKAHVRRGTA 375 Query: 360 RTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIK 394 L E QD+E L ++P NK + KI+ Sbjct: 376 FCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIR 410 >gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens] Length = 349 Score = 62.0 bits (149), Expect = 2e-09 Identities = 38/130 (29%), Positives = 61/130 (46%), Gaps = 8/130 (6%) Query: 272 QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIA--------ADGANALLPANRA 323 ++E + + A E+ RG F+ G E A CY R + +L AN A Sbjct: 200 ELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLA 259 Query: 324 MAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383 L + + + A + C + + + + KA RRG A+ LG L +A D + VL ++P N Sbjct: 260 ACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKN 319 Query: 384 KQAVTELSKI 393 + A EL K+ Sbjct: 320 RAAQEELGKV 329 Score = 56.2 bits (134), Expect = 9e-08 Identities = 42/144 (29%), Positives = 67/144 (46%), Gaps = 12/144 (8%) Query: 111 THESLSQESESEEDGIHVDSQKALVLKEK--GNKYFKQGKYDEAIDCYTKGM-------- 160 T S +Q +S E + ++AL +E+ G + F+ G + A CY + + Sbjct: 188 TLASFTQGRDSWE--LETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPP 245 Query: 161 DADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEA 220 P VL N A+ L + +A C+ + + KA RRG A+ AL LE+A Sbjct: 246 PGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKA 305 Query: 221 KKDYERVLELEPNNFEATNELRKI 244 D ++VL ++P N A EL K+ Sbjct: 306 TADLKKVLAIDPKNRAAQEELGKV 329 >gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo sapiens] Length = 1614 Score = 61.2 bits (147), Expect = 3e-09 Identities = 62/268 (23%), Positives = 110/268 (41%), Gaps = 14/268 (5%) Query: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTN 172 E+ Q + +H++ G QGK+ +A + +T +D DP N + Sbjct: 1355 EATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEG 1414 Query: 173 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232 RA ++ A D N A+ ++ + + + RG + + A KDY+ + L P Sbjct: 1415 RAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNP 1473 Query: 233 NNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGF 292 K S A + N Y ++++ K ++ + + + N Sbjct: 1474 ----------KYSLAYFNAGNIYFHHRQFS-QASDYFSKALKFDPENEYVLMNRAITNTI 1522 Query: 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352 K KYE A E + I + A + NRA Y +++YE AE+D +A+ L + + Sbjct: 1523 LK--KYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALV 1580 Query: 353 FARRGTARTFLGKLNEAKQDFETVLLLE 380 + R R +G + EA D+ L LE Sbjct: 1581 YNFRAKVRGKIGLIEEAMADYNQALDLE 1608 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/120 (29%), Positives = 59/120 (49%) Query: 112 HESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT 171 H SQ S+ + D + VL + KY+EA + + +++ P+ + Sbjct: 1489 HRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYF 1548 Query: 172 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 231 NRA Y+ LK++ +AE D N A++L + Y+ R R + +EEA DY + L+LE Sbjct: 1549 NRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608 Score = 41.2 bits (95), Expect = 0.003 Identities = 65/292 (22%), Positives = 116/292 (39%), Gaps = 61/292 (20%) Query: 143 YFKQGKYDE------AIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVAL 196 YF++G+ E AID ++K + DP R Y + + A D + + Sbjct: 1022 YFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNI 1081 Query: 197 NRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYP 256 + ++A RG ++ + AK ++ E++ + +EL + QAL S+ Sbjct: 1082 DHQNSQA---RGQYLLMMKYYDLAKFTIYQIAEMD----KGLSELSPMQQALIY---SFC 1131 Query: 257 KEADIVIKSTEG--------------ERKQIEAQQNKQ---------QAISEKDRGNG-- 291 + D I+ +G + Q++A++ K+ A S D+G Sbjct: 1132 ENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDASSHSDKGPDAT 1191 Query: 292 -------------FFKEGK----YERAIECYTRGIAADGANALLPANRAMAYLKIQKYEE 334 + +EG Y+ AI T I+ D + + NRA+ Y KI++ + Sbjct: 1192 TISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQM 1251 Query: 335 AEKDCTQAILLDGSYS---KAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383 A D +LLD + + F RG LG+ A +DF+ L+ N Sbjct: 1252 ALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTN 1303 Score = 38.5 bits (88), Expect = 0.020 Identities = 57/220 (25%), Positives = 96/220 (43%), Gaps = 35/220 (15%) Query: 203 AYSRRGAARFALQKLEEAKKDYERVLELEP---NNF--------------EATNELRKIS 245 AY RRGA L KL+ A D +RV+ LEP N + EA ++L I Sbjct: 919 AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIH 978 Query: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI-SEKDRGNGFFKEGK-YE---- 299 + + +Y +A+I G++ A N QAI S + +F+ G+ YE Sbjct: 979 KYNKNNTEAYLSKAEIY----RGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNK 1034 Query: 300 -RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGT 358 AI+ +++ I D R + Y + + + A +D T + +D S+A RG Sbjct: 1035 VLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQA---RGQ 1091 Query: 359 ARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELI 398 + + AK + ++ G ++ELS +++ LI Sbjct: 1092 YLLMMKYYDLAKFTIYQIAEMDKG----LSELSPMQQALI 1127 Score = 34.7 bits (78), Expect = 0.29 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%) Query: 287 DRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 346 +RG + + G+Y A+E + + N L AM + +I ++EEA T A+ ++ Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKIN 1334 Query: 347 GSYSKAFARRGTARTFLG---KLNEAKQDFETVLLLEP 381 + A+ RG + G +A++DF L + P Sbjct: 1335 PCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 1372 Score = 34.3 bits (77), Expect = 0.38 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 329 IQKYEEAEKDCTQAILLDGSYSK-AFARRGTARTFLGKLNEAKQDFETVLLLEP 381 I+ YE K T+ I Y A+ RRG LGKL A D + V+LLEP Sbjct: 895 IKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 948 >gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo sapiens] Length = 1614 Score = 61.2 bits (147), Expect = 3e-09 Identities = 62/268 (23%), Positives = 110/268 (41%), Gaps = 14/268 (5%) Query: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTN 172 E+ Q + +H++ G QGK+ +A + +T +D DP N + Sbjct: 1355 EATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEG 1414 Query: 173 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232 RA ++ A D N A+ ++ + + + RG + + A KDY+ + L P Sbjct: 1415 RAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNP 1473 Query: 233 NNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGF 292 K S A + N Y ++++ K ++ + + + N Sbjct: 1474 ----------KYSLAYFNAGNIYFHHRQFS-QASDYFSKALKFDPENEYVLMNRAITNTI 1522 Query: 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352 K KYE A E + I + A + NRA Y +++YE AE+D +A+ L + + Sbjct: 1523 LK--KYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALV 1580 Query: 353 FARRGTARTFLGKLNEAKQDFETVLLLE 380 + R R +G + EA D+ L LE Sbjct: 1581 YNFRAKVRGKIGLIEEAMADYNQALDLE 1608 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/120 (29%), Positives = 59/120 (49%) Query: 112 HESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT 171 H SQ S+ + D + VL + KY+EA + + +++ P+ + Sbjct: 1489 HRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYF 1548 Query: 172 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 231 NRA Y+ LK++ +AE D N A++L + Y+ R R + +EEA DY + L+LE Sbjct: 1549 NRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608 Score = 43.5 bits (101), Expect = 6e-04 Identities = 66/292 (22%), Positives = 117/292 (40%), Gaps = 61/292 (20%) Query: 143 YFKQGKYDE------AIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVAL 196 YF++G+ E AID ++K + DP R Y + + A D + + Sbjct: 1022 YFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNI 1081 Query: 197 NRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYP 256 + ++A RG ++ + AK ++ E++ + +EL + QAL S+ Sbjct: 1082 DHQNSQA---RGQYLLMMKYYDLAKFTIYQIAEMD----KGLSELSPMQQALIY---SFC 1131 Query: 257 KEADIVIKSTEG--------------ERKQIEAQQNKQ---------QAISEKDRGNG-- 291 + D I+ +G + Q++A++ K+ AIS D+G Sbjct: 1132 ENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDAT 1191 Query: 292 -------------FFKEGK----YERAIECYTRGIAADGANALLPANRAMAYLKIQKYEE 334 + +EG Y+ AI T I+ D + + NRA+ Y KI++ + Sbjct: 1192 AISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYIAFYNRALCYTKIRELQM 1251 Query: 335 AEKDCTQAILLDGSYS---KAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383 A D +LLD + + F RG LG+ A +DF+ L+ N Sbjct: 1252 ALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTN 1303 Score = 38.5 bits (88), Expect = 0.020 Identities = 57/220 (25%), Positives = 96/220 (43%), Gaps = 35/220 (15%) Query: 203 AYSRRGAARFALQKLEEAKKDYERVLELEP---NNF--------------EATNELRKIS 245 AY RRGA L KL+ A D +RV+ LEP N + EA ++L I Sbjct: 919 AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIH 978 Query: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI-SEKDRGNGFFKEGK-YE---- 299 + + +Y +A+I G++ A N QAI S + +F+ G+ YE Sbjct: 979 KYNKNNTEAYLSKAEIY----RGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNK 1034 Query: 300 -RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGT 358 AI+ +++ I D R + Y + + + A +D T + +D S+A RG Sbjct: 1035 VLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQA---RGQ 1091 Query: 359 ARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELI 398 + + AK + ++ G ++ELS +++ LI Sbjct: 1092 YLLMMKYYDLAKFTIYQIAEMDKG----LSELSPMQQALI 1127 Score = 34.7 bits (78), Expect = 0.29 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%) Query: 287 DRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 346 +RG + + G+Y A+E + + N L AM + +I ++EEA T A+ ++ Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKIN 1334 Query: 347 GSYSKAFARRGTARTFLG---KLNEAKQDFETVLLLEP 381 + A+ RG + G +A++DF L + P Sbjct: 1335 PCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 1372 Score = 34.3 bits (77), Expect = 0.38 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 329 IQKYEEAEKDCTQAILLDGSYSK-AFARRGTARTFLGKLNEAKQDFETVLLLEP 381 I+ YE K T+ I Y A+ RRG LGKL A D + V+LLEP Sbjct: 895 IKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 948 >gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo sapiens] Length = 1614 Score = 61.2 bits (147), Expect = 3e-09 Identities = 62/268 (23%), Positives = 110/268 (41%), Gaps = 14/268 (5%) Query: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTN 172 E+ Q + +H++ G QGK+ +A + +T +D DP N + Sbjct: 1355 EATKQAQKDFLKALHINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEG 1414 Query: 173 RASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232 RA ++ A D N A+ ++ + + + RG + + A KDY+ + L P Sbjct: 1415 RAVVCLQMGNNFAAMQDINAAMKISTT-AEFLTNRGVIHEFMGHKQNAMKDYQDAITLNP 1473 Query: 233 NNFEATNELRKISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGF 292 K S A + N Y ++++ K ++ + + + N Sbjct: 1474 ----------KYSLAYFNAGNIYFHHRQFS-QASDYFSKALKFDPENEYVLMNRAITNTI 1522 Query: 293 FKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKA 352 K KYE A E + I + A + NRA Y +++YE AE+D +A+ L + + Sbjct: 1523 LK--KYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALV 1580 Query: 353 FARRGTARTFLGKLNEAKQDFETVLLLE 380 + R R +G + EA D+ L LE Sbjct: 1581 YNFRAKVRGKIGLIEEAMADYNQALDLE 1608 Score = 58.9 bits (141), Expect = 1e-08 Identities = 35/120 (29%), Positives = 59/120 (49%) Query: 112 HESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPT 171 H SQ S+ + D + VL + KY+EA + + +++ P+ + Sbjct: 1489 HRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYF 1548 Query: 172 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 231 NRA Y+ LK++ +AE D N A++L + Y+ R R + +EEA DY + L+LE Sbjct: 1549 NRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLIEEAMADYNQALDLE 1608 Score = 42.4 bits (98), Expect = 0.001 Identities = 66/292 (22%), Positives = 116/292 (39%), Gaps = 61/292 (20%) Query: 143 YFKQGKYDE------AIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVAL 196 YF++G+ E AID ++K + DP R Y + + A D + + Sbjct: 1022 YFRRGEMYEITNKVLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNI 1081 Query: 197 NRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYP 256 + ++A RG ++ + AK ++ E++ + +EL + QAL S+ Sbjct: 1082 DHQNSQA---RGQYLLMMKYYDLAKFTIYQIAEMD----KGLSELSPMQQALIY---SFC 1131 Query: 257 KEADIVIKSTEG--------------ERKQIEAQQNKQ---------QAISEKDRGNG-- 291 + D I+ +G + Q++A++ K+ AIS D+G Sbjct: 1132 ENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDAT 1191 Query: 292 -------------FFKEGK----YERAIECYTRGIAADGANALLPANRAMAYLKIQKYEE 334 + +EG Y+ AI T I+ D + NRA+ Y KI++ + Sbjct: 1192 AISADCLYNLGLCYMEEGNLQMTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQM 1251 Query: 335 AEKDCTQAILLDGSYS---KAFARRGTARTFLGKLNEAKQDFETVLLLEPGN 383 A D +LLD + + F RG LG+ A +DF+ L+ N Sbjct: 1252 ALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALEDFKQAALISRTN 1303 Score = 38.5 bits (88), Expect = 0.020 Identities = 57/220 (25%), Positives = 96/220 (43%), Gaps = 35/220 (15%) Query: 203 AYSRRGAARFALQKLEEAKKDYERVLELEP---NNF--------------EATNELRKIS 245 AY RRGA L KL+ A D +RV+ LEP N + EA ++L I Sbjct: 919 AYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIH 978 Query: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAI-SEKDRGNGFFKEGK-YE---- 299 + + +Y +A+I G++ A N QAI S + +F+ G+ YE Sbjct: 979 KYNKNNTEAYLSKAEIY----RGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYEITNK 1034 Query: 300 -RAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGT 358 AI+ +++ I D R + Y + + + A +D T + +D S+A RG Sbjct: 1035 VLAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLNIDHQNSQA---RGQ 1091 Query: 359 ARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELI 398 + + AK + ++ G ++ELS +++ LI Sbjct: 1092 YLLMMKYYDLAKFTIYQIAEMDKG----LSELSPMQQALI 1127 Score = 34.7 bits (78), Expect = 0.29 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 3/98 (3%) Query: 287 DRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLD 346 +RG + + G+Y A+E + + N L AM + +I ++EEA T A+ ++ Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKIN 1334 Query: 347 GSYSKAFARRGTARTFLG---KLNEAKQDFETVLLLEP 381 + A+ RG + G +A++DF L + P Sbjct: 1335 PCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINP 1372 Score = 34.3 bits (77), Expect = 0.38 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 1/54 (1%) Query: 329 IQKYEEAEKDCTQAILLDGSYSK-AFARRGTARTFLGKLNEAKQDFETVLLLEP 381 I+ YE K T+ I Y A+ RRG LGKL A D + V+LLEP Sbjct: 895 IKYYESEVKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEP 948 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.129 0.354 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,912,968 Number of Sequences: 37866 Number of extensions: 1083912 Number of successful extensions: 5558 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 100 Number of HSP's successfully gapped in prelim test: 279 Number of HSP's that attempted gapping in prelim test: 4673 Number of HSP's gapped (non-prelim): 999 length of query: 665 length of database: 18,247,518 effective HSP length: 109 effective length of query: 556 effective length of database: 14,120,124 effective search space: 7850788944 effective search space used: 7850788944 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.