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Search of human proteins with 225703104
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225703104 major facilitator superfamily domain containing 10
[Homo sapiens]
(455 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225703102 major facilitator superfamily domain containing 10 ... 900 0.0
gi|225703104 major facilitator superfamily domain containing 10 ... 900 0.0
gi|217416366 major facilitator superfamily domain containing 9 [... 80 4e-15
gi|166064062 tumor suppressing subtransferable candidate 5 [Homo... 66 7e-11
gi|166064060 tumor suppressing subtransferable candidate 5 [Homo... 66 7e-11
gi|94721311 hippocampus abundant transcript-like 1 [Homo sapiens] 66 7e-11
gi|39753965 hippocampus abundant transcript 1 [Homo sapiens] 65 1e-10
gi|22749525 major facilitator superfamily domain containing 8 [H... 51 2e-06
gi|238814326 solute carrier family 22, member 20 [Homo sapiens] 48 2e-05
gi|21361449 solute carrier family 2 (facilitated glucose transpo... 47 3e-05
gi|8923870 solute carrier family 22 member 11 [Homo sapiens] 46 6e-05
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 43 5e-04
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 43 5e-04
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 43 5e-04
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 43 5e-04
gi|211059435 solute carrier family 22, member 24 [Homo sapiens] 41 0.002
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 41 0.003
gi|31543204 proton-coupled folate transporter [Homo sapiens] 40 0.003
gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 39 0.007
gi|118582257 vesicular acetylcholine transporter [Homo sapiens] 39 0.013
gi|148664184 solute carrier family 22, member 10 [Homo sapiens] 38 0.017
gi|194239645 spinster homolog 3 [Homo sapiens] 38 0.022
gi|215272392 solute carrier family 18 (vesicular monoamine), mem... 37 0.028
gi|215272390 solute carrier family 18 (vesicular monoamine), mem... 37 0.028
gi|208879454 solute carrier family 18 (vesicular monoamine), mem... 37 0.028
gi|4506987 solute carrier family 18 (vesicular monoamine), membe... 37 0.028
gi|42476325 solute carrier family 18 (vesicular monoamine), memb... 37 0.037
gi|203098995 solute carrier family 2 (facilitated glucose transp... 37 0.037
gi|185136021 spinster homolog 2 [Homo sapiens] 37 0.048
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 37 0.048
>gi|225703102 major facilitator superfamily domain containing 10
[Homo sapiens]
Length = 455
Score = 900 bits (2325), Expect = 0.0
Identities = 455/455 (100%), Positives = 455/455 (100%)
Query: 1 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL 60
MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL
Sbjct: 1 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL 60
Query: 61 YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM 120
YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM
Sbjct: 61 YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM 120
Query: 121 LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI 180
LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI
Sbjct: 121 LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI 180
Query: 181 GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR 240
GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR
Sbjct: 181 GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR 240
Query: 241 DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR 300
DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR
Sbjct: 241 DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR 300
Query: 301 FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP 360
FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP
Sbjct: 301 FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP 360
Query: 361 VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW 420
VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW
Sbjct: 361 VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW 420
Query: 421 LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE 455
LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
Sbjct: 421 LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE 455
>gi|225703104 major facilitator superfamily domain containing 10
[Homo sapiens]
Length = 455
Score = 900 bits (2325), Expect = 0.0
Identities = 455/455 (100%), Positives = 455/455 (100%)
Query: 1 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL 60
MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL
Sbjct: 1 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL 60
Query: 61 YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM 120
YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM
Sbjct: 61 YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM 120
Query: 121 LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI 180
LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI
Sbjct: 121 LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI 180
Query: 181 GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR 240
GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR
Sbjct: 181 GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR 240
Query: 241 DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR 300
DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR
Sbjct: 241 DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR 300
Query: 301 FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP 360
FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP
Sbjct: 301 FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP 360
Query: 361 VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW 420
VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW
Sbjct: 361 VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW 420
Query: 421 LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE 455
LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
Sbjct: 421 LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE 455
>gi|217416366 major facilitator superfamily domain containing 9
[Homo sapiens]
Length = 474
Score = 80.1 bits (196), Expect = 4e-15
Identities = 89/375 (23%), Positives = 162/375 (43%), Gaps = 29/375 (7%)
Query: 67 GVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMG 126
GV + + V+ S G++GS++ +LQ + L G SD +GRR +L C++
Sbjct: 59 GVSMVVPLLSLHVKSLGASPTVAGIVGSSYGILQLFSSTLVGCWSDVVGRRSSLLACILL 118
Query: 127 VATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSL 186
A Y + + + F+ +R+ GI K +S+S A+++D+ R + A +
Sbjct: 119 SALGYLLLGAATNVFLFVLARVPAGIFKHTLSISRALLSDVVPEKERPLVIGHFNTASGV 178
Query: 187 GFTLGPMLGASLPLEMAPWFALLFAASDLLFIF-----CFLP--ETLP------LEKRAP 233
GF LGP++G L E+ F L L+FI F P E P L R
Sbjct: 179 GFILGPVVGGYL-TELEDGFYLTAFICFLVFILNAGLVWFFPWREAKPGSTEKGLPLRKT 237
Query: 234 SIALGFRDAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLY---LFLFSGLE 290
+ LG + D + A R + ++ P + + +LR + + F +FL L
Sbjct: 238 HVLLG--RSHDTVQEAATSRRARASKKTAQPWVEVVLALRNMKNLLFSEMWDIFLVRLLM 295
Query: 291 YTLSFLTHQRFQFSSLQQ-GKMFFLIG--LTMATIQGAYA-------RRIHPGGEVAAVK 340
L + F + ++ G + G ++ +++ GA A R++ A +
Sbjct: 296 AMAVMLYYSNFVLALEERFGVRPKVTGYLISYSSMLGAVAGLALGPILRLYKHNSQALLL 355
Query: 341 RALLLLVPAFLLIGWGRSLPVLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTL 400
+ +L LL ++ + L L SF+ A+ C++ + G GT++G
Sbjct: 356 HSSILTCTLLLLYSLAPTMGAVVLSSTLLSFSTAIGRTCITDLQLTVGGAQASGTLIGVG 415
Query: 401 RSLGALARAAGPLVA 415
+S+ A+ R PL++
Sbjct: 416 QSVTAVGRIIAPLLS 430
>gi|166064062 tumor suppressing subtransferable candidate 5 [Homo
sapiens]
Length = 424
Score = 65.9 bits (159), Expect = 7e-11
Identities = 86/358 (24%), Positives = 142/358 (39%), Gaps = 48/358 (13%)
Query: 84 NSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAA- 142
+S+ FG L + F VLQ L P+ G +D G R + L + Y + A + S A
Sbjct: 57 DSIAFGYL-QTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALP 115
Query: 143 ----FLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASL 198
ASRL G + + + ++ DL +P R + +G+ F +G LG +LG +L
Sbjct: 116 GVYLLFASRLPGALMH-TLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTL 174
Query: 199 --------PLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFRDAA--DLLSP 248
P +A LL A +L C T + A + G A+ DL +
Sbjct: 175 VSAYGIQCPAILAALATLLGA---VLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAI 231
Query: 249 LALLRFSAVAR------GQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQRFQ 302
+LLR V R + P+G L++ +FS ++ FQ
Sbjct: 232 ASLLRLPDVPRIFLVKVASNCPTG--------------LFMVMFS-------IISMDFFQ 270
Query: 303 FSSLQQGKMFFLIGLTMATIQGAYARRIHPG-GEVAAVKRALLLLVPAFLLIGWGRSLPV 361
+ Q G + GL QG ++ E ++ ++L+ + L + W S+
Sbjct: 271 LEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVLLRASVLVFIVVGLAMAWMSSVFH 330
Query: 362 LGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVY 419
L + F+ + S++ S GT++G S+ L R GP V +Y
Sbjct: 331 FCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDTGTMLGLCASVQPLLRTLGPTVGGLLY 388
>gi|166064060 tumor suppressing subtransferable candidate 5 [Homo
sapiens]
Length = 424
Score = 65.9 bits (159), Expect = 7e-11
Identities = 86/358 (24%), Positives = 142/358 (39%), Gaps = 48/358 (13%)
Query: 84 NSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAA- 142
+S+ FG L + F VLQ L P+ G +D G R + L + Y + A + S A
Sbjct: 57 DSIAFGYL-QTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALP 115
Query: 143 ----FLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASL 198
ASRL G + + + ++ DL +P R + +G+ F +G LG +LG +L
Sbjct: 116 GVYLLFASRLPGALMH-TLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTL 174
Query: 199 --------PLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFRDAA--DLLSP 248
P +A LL A +L C T + A + G A+ DL +
Sbjct: 175 VSAYGIQCPAILAALATLLGA---VLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAI 231
Query: 249 LALLRFSAVAR------GQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQRFQ 302
+LLR V R + P+G L++ +FS ++ FQ
Sbjct: 232 ASLLRLPDVPRIFLVKVASNCPTG--------------LFMVMFS-------IISMDFFQ 270
Query: 303 FSSLQQGKMFFLIGLTMATIQGAYARRIHPG-GEVAAVKRALLLLVPAFLLIGWGRSLPV 361
+ Q G + GL QG ++ E ++ ++L+ + L + W S+
Sbjct: 271 LEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVLLRASVLVFIVVGLAMAWMSSVFH 330
Query: 362 LGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVY 419
L + F+ + S++ S GT++G S+ L R GP V +Y
Sbjct: 331 FCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDTGTMLGLCASVQPLLRTLGPTVGGLLY 388
>gi|94721311 hippocampus abundant transcript-like 1 [Homo sapiens]
Length = 506
Score = 65.9 bits (159), Expect = 7e-11
Identities = 80/350 (22%), Positives = 136/350 (38%), Gaps = 35/350 (10%)
Query: 84 NSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAF 143
++ L GLI +L FL APL GA SD GR+P +L + T + + S +
Sbjct: 77 HTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVF--FTCFPIPLMRISPWWY 134
Query: 144 LASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPL--- 200
A + G+ S+ A VAD+ RS + F+ P +GA L
Sbjct: 135 FAMISVSGVFSVTFSVIFAYVADVTQEHERSTAYGWVSATFAASLVSSPAIGAYLSASYG 194
Query: 201 -EMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFRDAADLLSPLALLRFSAVAR 259
+ A + A D+ FI +PE+LP EK P ++ G + + P A L+
Sbjct: 195 DSLVVLVATVVALLDICFILVAVPESLP-EKMRP-VSWGAQISWKQADPFASLK----KV 248
Query: 260 GQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTM 319
G+D S++ + + FL +G + Q F S++ ++G+
Sbjct: 249 GKD-------STVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIAAFIAMVGILS 301
Query: 320 ATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLPVLGLGLLLYSFAAA----- 374
Q A+ + + LL L L + W G G + AA
Sbjct: 302 IVAQTAFLSILM--RSLGNKNTVLLGLGFQMLQLAW------YGFGSQAWMMWAAGTVAA 353
Query: 375 ---VVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYWL 421
+ P +S++V+ Q+G G + + L GP + ++++
Sbjct: 354 MSSITFPAISALVSRNAESDQQGVAQGIITGIRGLCNGLGPALYGFIFYM 403
>gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]
Length = 490
Score = 65.1 bits (157), Expect = 1e-10
Identities = 81/347 (23%), Positives = 140/347 (40%), Gaps = 29/347 (8%)
Query: 84 NSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAF 143
++ L GLI +L FL APL GA SD GR+ +LL + + S + +
Sbjct: 69 HTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWW--Y 126
Query: 144 LASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAF--------SLGFTLGPMLG 195
A + G+ S+ A VAD+ RS ++ F ++G LG + G
Sbjct: 127 FAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGRVYG 186
Query: 196 ASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFRDAADLLSPLALLRFS 255
SL + +A ALL D+ FI +PE+LP EK P+ + G + + P A L+
Sbjct: 187 DSLVVVLATAIALL----DICFILVAVPESLP-EKMRPA-SWGAPISWEQADPFASLK-- 238
Query: 256 AVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLI 315
GQD S + + + FL +G + Q +FS ++
Sbjct: 239 --KVGQD-------SIVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFSPESVAAFIAVL 289
Query: 316 GLTMATIQG-AYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLPVLGLGLLLYSFAAA 374
G+ Q + + G + L + G+G S P + + ++
Sbjct: 290 GILSIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFG-SEPWMMWAAGAVAAMSS 348
Query: 375 VVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYWL 421
+ P +S++V+ Q+G V G + + L GP + ++++
Sbjct: 349 ITFPAVSALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYI 395
>gi|22749525 major facilitator superfamily domain containing 8 [Homo
sapiens]
Length = 518
Score = 51.2 bits (121), Expect = 2e-06
Identities = 98/442 (22%), Positives = 171/442 (38%), Gaps = 104/442 (23%)
Query: 88 FGGLIGSAFSVLQFLCAPLTGATSDCLGRR-PVMLLCLMGVATS----YAVWATSRSFAA 142
F G + +++S+ Q + +P+ G S+ R+ P+++ L+ VA + Y S +
Sbjct: 75 FLGWVIASYSLGQMVASPIFGLWSNYRPRKEPLIVSILISVAANCLYAYLHIPASHNKYY 134
Query: 143 FLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPM-------LG 195
L +R + GI GNV++ + A S R+ MA I + +LGF LGP+ LG
Sbjct: 135 MLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLG 194
Query: 196 --------ASLPLEMAPWFALLFA---ASDLLFIFCFLPETLPLEKRAPSIALGFRDAAD 244
L + M LL A +++ I L E + ++ F +A
Sbjct: 195 EKGVTWDVIKLQINMYTTPVLLSAFLGILNIILILAILREHRVDDSGRQCKSINFEEA-- 252
Query: 245 LLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQRFQFS 304
+ Q P ++ + +++F+ LF+F+ E ++ LT + ++
Sbjct: 253 -----------STDEAQVPQGNIDQVAVVAINVLFFVTLFIFALFETIITPLTMDMYAWT 301
Query: 305 SLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVK---RALLL------LVPAFLLIGW 355
Q + G+ +A + G A I G ++ + K RA+LL V F+L+ W
Sbjct: 302 ---QEQAVLYNGIILAAL-GVEAVVIFLGVKLLSKKIGERAILLGGLIVVWVGFFILLPW 357
Query: 356 GRSLP--------------------VLGL-------------------GLLLYSFAAAVV 376
G P ++GL LY+ +
Sbjct: 358 GNQFPKIQWEDLHNNSIPNTTFGEIIIGLWKSPMEDDNERPTGCSIEQAWCLYTPVIHLA 417
Query: 377 VPCLSSVVAGYG----------------SPGQKGTVMGTLRSLGALARAAGPLVAASVYW 420
S+V+ G G P +G MG L + G+ AR GP+ + VY
Sbjct: 418 QFLTSAVLIGLGYPVCNLMSYTLYSKILGPKPQGVYMGWLTASGSGARILGPMFISQVYA 477
Query: 421 LAGAQACFTTWSGLFLLPFFLL 442
G + F+ G+ +L LL
Sbjct: 478 HWGPRWAFSLVCGIIVLTITLL 499
>gi|238814326 solute carrier family 22, member 20 [Homo sapiens]
Length = 555
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 104 APLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAI 163
A + G+ +D LG + ++ + +A S A A SF+A+ R + G++ + L++
Sbjct: 151 AAVFGSLADRLGCKGPLVWSYLQLAASGAATAYFSSFSAYCVFRFLMGMTFSGIILNSVS 210
Query: 164 VADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLP 223
+ P ++G V G+ FTLG ++ A + + PW L FA S IF
Sbjct: 211 LVVEWMP---TRGRTVAGILLGYSFTLGQLILAGVAYLIRPWRCLQFAISAPFLIFFLYS 267
Query: 224 ETLPLEKR 231
LP R
Sbjct: 268 WWLPESSR 275
>gi|21361449 solute carrier family 2 (facilitated glucose
transporter), member 8 [Homo sapiens]
Length = 477
Score = 47.4 bits (111), Expect = 3e-05
Identities = 64/272 (23%), Positives = 102/272 (37%), Gaps = 40/272 (14%)
Query: 13 PPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPLYGSWQGGVDWFA 72
PP P RRV F L L+F L + S RA P WF
Sbjct: 15 PPGGSAPRGRRVFLAAFAAAL-GPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFG 73
Query: 73 TAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYA 132
+ + GG++G G D GR+ +LLC + +A
Sbjct: 74 AVVTL-------GAAAGGVLG--------------GWLVDRAGRKLSLLLCSVPFVAGFA 112
Query: 133 VWATSRSFAAFLASRLIGGISKGNVSLSTAI-VADLGSPLARSQGMAVIGVAFSLGFTLG 191
V ++ L RL+ G++ G SL + ++++ P R + + + +G L
Sbjct: 113 VITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA 172
Query: 192 PMLGASLPLEMAPWFALL--FAASDLLFIFCFLPETLPLEKRAPSIALGFRDAADLLSPL 249
+ G L W A+L S +L + CF+PET P L + ++ L
Sbjct: 173 YLAGWVLEWR---WLAVLGCVPPSLMLLLMCFMPET-------PRFLLTQHRRQEAMAAL 222
Query: 250 ALLRFSAVARGQDPPSGD----RLSSLRRLGL 277
L + + +DPP G L+ LR+ G+
Sbjct: 223 RFL-WGSEQGWEDPPIGAEQSFHLALLRQPGI 253
>gi|8923870 solute carrier family 22 member 11 [Homo sapiens]
Length = 550
Score = 46.2 bits (108), Expect = 6e-05
Identities = 86/360 (23%), Positives = 135/360 (37%), Gaps = 48/360 (13%)
Query: 85 SVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFL 144
S+ G++ +F + G S GR+P++ C + +A + + +F +
Sbjct: 147 SIFMSGILVGSF---------IWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYC 197
Query: 145 ASRLIGGISKGNVSLST-AIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA 203
R + + LS+ ++ + + R+ M V+G AFS G LG L +
Sbjct: 198 GLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVGCAFSAGQAA---LGG-LAFALR 253
Query: 204 PWFALLFAASDLLFIFCFLPETLP------LEKRAPSIAL----------GFRDAADLLS 247
W L AAS F + LP + K P AL G ++A +L
Sbjct: 254 DWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTI 313
Query: 248 PLALLRFSA-VARGQDPPSGDRLSSLRRLG-------LVYFLYLFLFSGLEYTLSFLTHQ 299
+ + VA ++P S L + L +V F L + GL + L L
Sbjct: 314 EVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNFSLLISYYGLVFDLQSLGRD 373
Query: 300 RFQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALL--LLVPAFLLIGWGR 357
F +L G + FL T A + RR G A A+L +LVP L
Sbjct: 374 IFLLQALF-GAVDFLGRATTALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQT-LRV 431
Query: 358 SLPVLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAAS 417
VLG G + + CL+ A + T G L ++G L GPL+ S
Sbjct: 432 VFAVLGKGCF------GISLTCLTIYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMS 485
>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
sapiens]
Length = 519
Score = 43.1 bits (100), Expect = 5e-04
Identities = 44/177 (24%), Positives = 70/177 (39%), Gaps = 3/177 (1%)
Query: 43 LPLLPGLLESHGRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFL 102
LP L G + A +P W F + I + + L S + V L
Sbjct: 88 LPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLL 147
Query: 103 CAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTA 162
A + G +D LGRR V++L + A S A + +F + A RL+ G++ +SL+
Sbjct: 148 GAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCM 207
Query: 163 IVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIF 219
+ P+ A +G ++LG L A + + W L S F F
Sbjct: 208 TLNVEWMPI---HTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAF 261
>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
sapiens]
Length = 506
Score = 43.1 bits (100), Expect = 5e-04
Identities = 44/177 (24%), Positives = 70/177 (39%), Gaps = 3/177 (1%)
Query: 43 LPLLPGLLESHGRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFL 102
LP L G + A +P W F + I + + L S + V L
Sbjct: 88 LPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLL 147
Query: 103 CAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTA 162
A + G +D LGRR V++L + A S A + +F + A RL+ G++ +SL+
Sbjct: 148 GAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCM 207
Query: 163 IVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIF 219
+ P+ A +G ++LG L A + + W L S F F
Sbjct: 208 TLNVEWMPI---HTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAF 261
>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
sapiens]
Length = 550
Score = 43.1 bits (100), Expect = 5e-04
Identities = 44/177 (24%), Positives = 70/177 (39%), Gaps = 3/177 (1%)
Query: 43 LPLLPGLLESHGRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFL 102
LP L G + A +P W F + I + + L S + V L
Sbjct: 88 LPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLL 147
Query: 103 CAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTA 162
A + G +D LGRR V++L + A S A + +F + A RL+ G++ +SL+
Sbjct: 148 GAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCM 207
Query: 163 IVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIF 219
+ P+ A +G ++LG L A + + W L S F F
Sbjct: 208 TLNVEWMPI---HTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAF 261
>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
sapiens]
Length = 563
Score = 43.1 bits (100), Expect = 5e-04
Identities = 44/177 (24%), Positives = 70/177 (39%), Gaps = 3/177 (1%)
Query: 43 LPLLPGLLESHGRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFL 102
LP L G + A +P W F + I + + L S + V L
Sbjct: 88 LPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLL 147
Query: 103 CAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTA 162
A + G +D LGRR V++L + A S A + +F + A RL+ G++ +SL+
Sbjct: 148 GAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCM 207
Query: 163 IVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIF 219
+ P+ A +G ++LG L A + + W L S F F
Sbjct: 208 TLNVEWMPI---HTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAF 261
>gi|211059435 solute carrier family 22, member 24 [Homo sapiens]
Length = 551
Score = 41.2 bits (95), Expect = 0.002
Identities = 31/128 (24%), Positives = 55/128 (42%), Gaps = 3/128 (2%)
Query: 91 LIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIG 150
++ S F L + G SD +GR+ + LC + +A S A + +F + R +
Sbjct: 147 MVQSLFMAGSLLGGLIYGHLSDRVGRKIICKLCFLQLAISNTCAAFAPTFLVYCILRFLA 206
Query: 151 GISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLF 210
G S + L + L L RS+ M ++ + S +++G ML L + W L
Sbjct: 207 GFSTMTI-LGNTFILSLEWTLPRSRSMTIMVLLCS--YSVGQMLLGGLAFAIQDWHILQL 263
Query: 211 AASDLLFI 218
S + +
Sbjct: 264 TVSTPIIV 271
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 40.8 bits (94), Expect = 0.003
Identities = 44/163 (26%), Positives = 67/163 (41%), Gaps = 10/163 (6%)
Query: 108 GATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADL 167
G SD GRRP++ + +A S + A S +F ++ R + G ++LST I L
Sbjct: 141 GDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVI---L 197
Query: 168 GSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLP 227
++ A++ A +T G + L + W L S F+F FL
Sbjct: 198 NVEWVPTRMRAIMSTALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVF-FLSSWWT 256
Query: 228 LEKRAPSIALGFRDAADLLSPLALLRFSAVARGQDPPSGDRLS 270
E + G A L +LR AV G+ G+RLS
Sbjct: 257 PESIRWLVLSGKSSKA-----LKILRRVAVFNGK-KEEGERLS 293
>gi|31543204 proton-coupled folate transporter [Homo sapiens]
Length = 459
Score = 40.4 bits (93), Expect = 0.003
Identities = 46/145 (31%), Positives = 64/145 (44%), Gaps = 18/145 (12%)
Query: 89 GGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGV----ATSYAVWATSRSFAAFL 144
GG + FS + L GA SD +GRRP+++L +G+ S V F+
Sbjct: 92 GGFLVGLFS------STLLGAWSDSVGRRPLLVLASLGLLLQALVSVFVVQLQLHVGYFV 145
Query: 145 ASRLIG---GISKGNVSLSTAIVADLGSPLARSQGMAV----IGVAFSLGFTLGPMLGAS 197
R++ G G ++ S A VAD+ S +R+ MA+ IGVA L LG +
Sbjct: 146 LGRILCALLGDFGGLLAASFASVADVSSSRSRTFRMALLEASIGVAGMLASLLGGHWLRA 205
Query: 198 LPLEMAPWFAL-LFAASDLLFIFCF 221
W AL L A L FCF
Sbjct: 206 QGYANPFWLALALLIAMTLYAAFCF 230
>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
Length = 556
Score = 39.3 bits (90), Expect = 0.007
Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 6/135 (4%)
Query: 99 LQFLCAPLT-GATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGI-SKGN 156
L FL T G +D GR + LL +GV + V A + +F F+ R + G+ KG
Sbjct: 163 LGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGT 222
Query: 157 VSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLL 216
IV ++ S+ ++G+ + FTLG ++ + + W + A +
Sbjct: 223 WMTCYVIVTEI----VGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPS 278
Query: 217 FIFCFLPETLPLEKR 231
F+F +P R
Sbjct: 279 FLFLLYYWVVPESPR 293
>gi|118582257 vesicular acetylcholine transporter [Homo sapiens]
Length = 532
Score = 38.5 bits (88), Expect = 0.013
Identities = 49/211 (23%), Positives = 86/211 (40%), Gaps = 30/211 (14%)
Query: 17 QQPPERR--VVTVVFLGLLLDLLAFTLLLPLLPGLLESHGR------------------- 55
Q+P +R V+ +V + LLLD + + +++P++P + +H R
Sbjct: 26 QEPRRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYI-AHMRGGGEGPTRTPEVWEPTLPL 84
Query: 56 ---AHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFS---VLQFLCAPLTGA 109
A+ Y + A G + RY + IG F+ +LQ L PL+G
Sbjct: 85 PTPANASAYTANTSASPTAAWPAGSALRPRYPTESEDVKIGVLFASKAILQLLVNPLSGP 144
Query: 110 TSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLS-TAIVAD-L 167
D + +L+ L + S ++A + +A A+R + G+ S A++AD
Sbjct: 145 FIDRMSYDVPLLIGLGVMFASTVLFAFAEDYATLFAARSLQGLGSAFADTSGIAMIADKY 204
Query: 168 GSPLARSQGMAVIGVAFSLGFTLGPMLGASL 198
RS+ + V S G + P G L
Sbjct: 205 PEEPERSRALGVALAFISFGSLVAPPFGGIL 235
>gi|148664184 solute carrier family 22, member 10 [Homo sapiens]
Length = 541
Score = 38.1 bits (87), Expect = 0.017
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 16/140 (11%)
Query: 97 SVLQFLCAP-------LTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLI 149
SV+QFL + G SD GRR ++ CL+ +A + A + +F + R +
Sbjct: 146 SVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCLLQLAITDTCAAFAPTFPVYCVLRFL 205
Query: 150 GGISKGNVSLSTAIVADLGSPLA---RSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWF 206
G S S I+++ P+ R A++ + S ++G ++ L W
Sbjct: 206 AGFS------SMIIISNNSLPITEWIRPNSKALVVILSSGALSIGQIILGGLAYVFRDWQ 259
Query: 207 ALLFAASDLLFIFCFLPETL 226
L AS F+F L L
Sbjct: 260 TLHVVASVPFFVFFLLSRWL 279
>gi|194239645 spinster homolog 3 [Homo sapiens]
Length = 512
Score = 37.7 bits (86), Expect = 0.022
Identities = 29/119 (24%), Positives = 55/119 (46%), Gaps = 3/119 (2%)
Query: 90 GLIGSAFSVLQFLCAPLTGATSDCLGRRPVM---LLCLMGVATSYAVWATSRSFAAFLAS 146
GL+ + F L AP+ G D R+ M +L G S + + S+ FL+
Sbjct: 84 GLLQTVFVSCLLLSAPVFGYLGDRHSRKATMSFGILLWSGAGLSSSFISPRYSWLFFLSR 143
Query: 147 RLIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPW 205
++G S +++ ++ DL R++ +AV + +G LG +LG+++ + W
Sbjct: 144 GIVGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSGLGYVLGSAVTMLTGNW 202
>gi|215272392 solute carrier family 18 (vesicular monoamine), member
1 isoform c [Homo sapiens]
Length = 472
Score = 37.4 bits (85), Expect = 0.028
Identities = 57/256 (22%), Positives = 98/256 (38%), Gaps = 61/256 (23%)
Query: 24 VVTVVFLGLLLDLLAFTLLLPLLPGLL------ESHGRAH------------DPLYG--- 62
V+ VVF+ LLLD + FT+++P++P L E + H P +
Sbjct: 23 VLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHALASPAFSTIF 82
Query: 63 ------------SWQGGVDWF---ATAIGMP----VEKRYNSVLFG-----------GLI 92
S G+ W A+ I P + N+ L G G++
Sbjct: 83 SFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVL 142
Query: 93 GSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGI 152
++ +V+Q L P G ++ +G M + + S ++A S ++ +R + GI
Sbjct: 143 FASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGI 202
Query: 153 SKGNVSLS----TAIVADLGSPLARSQGMAVIGVAFSL------GFTLGPMLGASLPLEM 202
S++ A V R+ G A+ G+A L G + +G S P +
Sbjct: 203 GSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLI 262
Query: 203 APWFALLFAASDLLFI 218
+ ALL A L +
Sbjct: 263 LAFLALLDGALQLCIL 278
>gi|215272390 solute carrier family 18 (vesicular monoamine), member
1 isoform b [Homo sapiens]
Length = 493
Score = 37.4 bits (85), Expect = 0.028
Identities = 57/256 (22%), Positives = 98/256 (38%), Gaps = 61/256 (23%)
Query: 24 VVTVVFLGLLLDLLAFTLLLPLLPGLL------ESHGRAH------------DPLYG--- 62
V+ VVF+ LLLD + FT+++P++P L E + H P +
Sbjct: 23 VLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHALASPAFSTIF 82
Query: 63 ------------SWQGGVDWF---ATAIGMP----VEKRYNSVLFG-----------GLI 92
S G+ W A+ I P + N+ L G G++
Sbjct: 83 SFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVL 142
Query: 93 GSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGI 152
++ +V+Q L P G ++ +G M + + S ++A S ++ +R + GI
Sbjct: 143 FASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGI 202
Query: 153 SKGNVSLS----TAIVADLGSPLARSQGMAVIGVAFSL------GFTLGPMLGASLPLEM 202
S++ A V R+ G A+ G+A L G + +G S P +
Sbjct: 203 GSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLI 262
Query: 203 APWFALLFAASDLLFI 218
+ ALL A L +
Sbjct: 263 LAFLALLDGALQLCIL 278
Score = 33.5 bits (75), Expect = 0.41
Identities = 32/152 (21%), Positives = 62/152 (40%), Gaps = 6/152 (3%)
Query: 90 GLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLI 149
GL SV + L G ++ +GR L+ ++ V TS + + +
Sbjct: 307 GLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNAG 366
Query: 150 GGISKGNVSLSTAIV----ADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA-P 204
G++ G V S + DL A+ VAF +GF +GP G ++ + P
Sbjct: 367 LGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGFP 426
Query: 205 WFALLFAASDLLFI-FCFLPETLPLEKRAPSI 235
W ++ ++++ C+ + P ++ +I
Sbjct: 427 WLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 458
>gi|208879454 solute carrier family 18 (vesicular monoamine), member
1 isoform a [Homo sapiens]
Length = 525
Score = 37.4 bits (85), Expect = 0.028
Identities = 57/256 (22%), Positives = 98/256 (38%), Gaps = 61/256 (23%)
Query: 24 VVTVVFLGLLLDLLAFTLLLPLLPGLL------ESHGRAH------------DPLYG--- 62
V+ VVF+ LLLD + FT+++P++P L E + H P +
Sbjct: 23 VLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHALASPAFSTIF 82
Query: 63 ------------SWQGGVDWF---ATAIGMP----VEKRYNSVLFG-----------GLI 92
S G+ W A+ I P + N+ L G G++
Sbjct: 83 SFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVL 142
Query: 93 GSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGI 152
++ +V+Q L P G ++ +G M + + S ++A S ++ +R + GI
Sbjct: 143 FASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGI 202
Query: 153 SKGNVSLS----TAIVADLGSPLARSQGMAVIGVAFSL------GFTLGPMLGASLPLEM 202
S++ A V R+ G A+ G+A L G + +G S P +
Sbjct: 203 GSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLI 262
Query: 203 APWFALLFAASDLLFI 218
+ ALL A L +
Sbjct: 263 LAFLALLDGALQLCIL 278
Score = 33.9 bits (76), Expect = 0.31
Identities = 33/153 (21%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 92 IGSAF---SVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRL 148
+G AF SV + L G ++ +GR L+ ++ V TS + + +
Sbjct: 338 LGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNA 397
Query: 149 IGGISKGNVSLSTAIV----ADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA- 203
G++ G V S + DL A+ VAF +GF +GP G ++ +
Sbjct: 398 GLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGF 457
Query: 204 PWFALLFAASDLLFI-FCFLPETLPLEKRAPSI 235
PW ++ ++++ C+ + P ++ +I
Sbjct: 458 PWLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 490
>gi|4506987 solute carrier family 18 (vesicular monoamine), member 1
isoform a [Homo sapiens]
Length = 525
Score = 37.4 bits (85), Expect = 0.028
Identities = 57/256 (22%), Positives = 98/256 (38%), Gaps = 61/256 (23%)
Query: 24 VVTVVFLGLLLDLLAFTLLLPLLPGLL------ESHGRAH------------DPLYG--- 62
V+ VVF+ LLLD + FT+++P++P L E + H P +
Sbjct: 23 VLVVVFVALLLDNMLFTVVVPIVPTFLYDMEFKEVNSSLHLGHAGSSPHALASPAFSTIF 82
Query: 63 ------------SWQGGVDWF---ATAIGMP----VEKRYNSVLFG-----------GLI 92
S G+ W A+ I P + N+ L G G++
Sbjct: 83 SFFNNNTVAVEESVPSGIAWMNDTASTIPPPATEAISAHKNNCLQGTGFLEEEITRVGVL 142
Query: 93 GSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGI 152
++ +V+Q L P G ++ +G M + + S ++A S ++ +R + GI
Sbjct: 143 FASKAVMQLLVNPFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFVARTLQGI 202
Query: 153 SKGNVSLS----TAIVADLGSPLARSQGMAVIGVAFSL------GFTLGPMLGASLPLEM 202
S++ A V R+ G A+ G+A L G + +G S P +
Sbjct: 203 GSSFSSVAGLGMLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLI 262
Query: 203 APWFALLFAASDLLFI 218
+ ALL A L +
Sbjct: 263 LAFLALLDGALQLCIL 278
Score = 33.9 bits (76), Expect = 0.31
Identities = 33/153 (21%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 92 IGSAF---SVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRL 148
+G AF SV + L G ++ +GR L+ ++ V TS + + +
Sbjct: 338 LGLAFLPASVSYLIGTNLFGVLANKMGRWLCSLIGMLVVGTSLLCVPLAHNIFGLIGPNA 397
Query: 149 IGGISKGNVSLSTAIV----ADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA- 203
G++ G V S + DL A+ VAF +GF +GP G ++ +
Sbjct: 398 GLGLAIGMVDSSMMPIMGHLVDLRHTSVYGSVYAIADVAFCMGFAIGPSTGGAIVKAIGF 457
Query: 204 PWFALLFAASDLLFI-FCFLPETLPLEKRAPSI 235
PW ++ ++++ C+ + P ++ +I
Sbjct: 458 PWLMVITGVINIVYAPLCYYLRSPPAKEEKLAI 490
>gi|42476325 solute carrier family 18 (vesicular monoamine), member
2 [Homo sapiens]
Length = 514
Score = 37.0 bits (84), Expect = 0.037
Identities = 35/155 (22%), Positives = 63/155 (40%), Gaps = 9/155 (5%)
Query: 92 IGSAF---SVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRL 148
+G AF S+ + + G + +GR LL ++ V S +++ +A
Sbjct: 330 LGVAFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSILCIPFAKNIYGLIAPNF 389
Query: 149 IGGISKGNVSLST----AIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMA- 203
G + G V S + DL A+ VAF +G+ +GP G ++ +
Sbjct: 390 GVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGF 449
Query: 204 PWFALLFAASDLLFI-FCFLPETLPLEKRAPSIAL 237
PW + D+LF CF + P ++ +I +
Sbjct: 450 PWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAILM 484
Score = 30.0 bits (66), Expect = 4.5
Identities = 12/29 (41%), Positives = 21/29 (72%)
Query: 24 VVTVVFLGLLLDLLAFTLLLPLLPGLLES 52
++ +VFL LLLD + T+++P++P L S
Sbjct: 22 ILFIVFLALLLDNMLLTVVVPIIPSYLYS 50
>gi|203098995 solute carrier family 2 (facilitated glucose
transporter), member 13 [Homo sapiens]
Length = 648
Score = 37.0 bits (84), Expect = 0.037
Identities = 36/125 (28%), Positives = 55/125 (44%), Gaps = 8/125 (6%)
Query: 108 GATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAI-VAD 166
GA + GRR +LL AV A + + LA RL+ G+ G S++ + +A+
Sbjct: 139 GALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAE 198
Query: 167 LGSPLARSQGMAVIGVAFSLG--FTLGPMLGASLPLEMAPWFALLFAAS----DLLFIFC 220
+ P R + + I F G F + GA L+ W +L A+ F F
Sbjct: 199 VSPPNLRGR-LVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFL 257
Query: 221 FLPET 225
FLPE+
Sbjct: 258 FLPES 262
>gi|185136021 spinster homolog 2 [Homo sapiens]
Length = 549
Score = 36.6 bits (83), Expect = 0.048
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 5/120 (4%)
Query: 90 GLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLC---LMGVATSYAVWATSRSFAAFLAS 146
GL+ S F + AP+ G D R+ V+L C T + + + F + S
Sbjct: 141 GLLQSVFICSFMVAAPIFGYLGDRFNRK-VILSCGIFFWSAVTFSSSFIPQQYFWLLVLS 199
Query: 147 RLIGGISKGNVS-LSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPW 205
R + GI + + S ++ I+ DL + R+ ++V A LG LG + G+S+ W
Sbjct: 200 RGLVGIGEASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITGSSVKQAAGDW 259
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 36.6 bits (83), Expect = 0.048
Identities = 51/180 (28%), Positives = 77/180 (42%), Gaps = 32/180 (17%)
Query: 55 RAHDPLYGSWQGGVDWFATAIGMPVEKRYNSV--------LFGGLIGSAFSVLQFLCAPL 106
R+H PL G Q G W G + +N V LF + + F L L
Sbjct: 113 RSHLPL-GPCQDG--WVYDTPGSSIVTEFNLVCADSWKLDLFQSCLNAGF-----LFGSL 164
Query: 107 -TGATSDCLGRRPVMLLCLMGV----ATSYAVWATSRSFAAFLASRLIGG-ISKGN-VSL 159
G +D GR+ LCL+G A S + A S ++ + L RL+ G +SKGN ++
Sbjct: 165 GVGYFADRFGRK----LCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAG 220
Query: 160 STAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIF 219
T I +GS R+ + + + + FT+G + L + W L A S F+F
Sbjct: 221 YTLITEFVGSGSRRT-----VAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLF 275
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.142 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,061,142
Number of Sequences: 37866
Number of extensions: 751750
Number of successful extensions: 2664
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 2585
Number of HSP's gapped (non-prelim): 97
length of query: 455
length of database: 18,247,518
effective HSP length: 106
effective length of query: 349
effective length of database: 14,233,722
effective search space: 4967568978
effective search space used: 4967568978
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.