Search of human proteins with 224809578

Search of human proteins with 224809578

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224809578 RAP1 GTPase activating protein isoform a [Homo
sapiens]
         (727 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224809578 RAP1 GTPase activating protein isoform a [Homo sapi...  1474   0.0  
gi|224809582 RAP1 GTPase activating protein isoform c [Homo sapi...  1343   0.0  
gi|224809573 RAP1 GTPase activating protein isoform b [Homo sapi...  1303   0.0  
gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform ...   667   0.0  
gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform ...   647   0.0  
gi|71143119 signal-induced proliferation-associated 1 like 3 [Ho...   224   2e-58
gi|7662126 signal-induced proliferation-associated 1 like 1 [Hom...   222   1e-57
gi|112421013 signal-induced proliferation-associated 1 like 2 [H...   221   2e-57
gi|207448705 GTPase activating Rap/RanGAP domain-like 3 [Homo sa...   211   3e-54
gi|206725526 signal-induced proliferation-associated protein 1 [...   210   3e-54
gi|206725523 signal-induced proliferation-associated protein 1 [...   210   3e-54
gi|118600961 akt substrate AS250 [Homo sapiens]                        82   2e-15
gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2...    77   6e-14
gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1...    77   6e-14
gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]             73   8e-13
gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]             73   8e-13
gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]             73   8e-13
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         44   5e-04
gi|113415504 PREDICTED: similar to ribonucleic acid binding prot...    43   0.001
gi|169166499 PREDICTED: similar to ribonucleic acid binding prot...    43   0.001
gi|113415498 PREDICTED: similar to ribonucleic acid binding prot...    43   0.001
gi|88973230 PREDICTED: similar to ribonucleic acid binding prote...    43   0.001
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot...    42   0.002
gi|113415994 PREDICTED: similar to ribonucleic acid binding prot...    42   0.002
gi|6857826 RNA-binding protein S1, serine-rich domain [Homo sapi...    42   0.002
gi|18379334 RNA-binding protein S1, serine-rich domain [Homo sap...    42   0.002
gi|29570782 additional sex combs like 1 [Homo sapiens]                 40   0.006
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         40   0.008
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    40   0.010
gi|20070163 voltage-dependent calcium channel alpha 1G subunit i...    39   0.017

>gi|224809578 RAP1 GTPase activating protein isoform a [Homo
           sapiens]
          Length = 727

 Score = 1474 bits (3816), Expect = 0.0
 Identities = 727/727 (100%), Positives = 727/727 (100%)

Query: 1   MSGRKRSFTFGAYGGVDKSFTSRRSVWRSDGQNQHFPQALDLSRVNLVPSYTPSLYPKNT 60
           MSGRKRSFTFGAYGGVDKSFTSRRSVWRSDGQNQHFPQALDLSRVNLVPSYTPSLYPKNT
Sbjct: 1   MSGRKRSFTFGAYGGVDKSFTSRRSVWRSDGQNQHFPQALDLSRVNLVPSYTPSLYPKNT 60

Query: 61  DLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWI 120
           DLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWI
Sbjct: 61  DLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWI 120

Query: 121 EGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSL 180
           EGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSL
Sbjct: 121 EGTNHEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSL 180

Query: 181 KYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPK 240
           KYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPK
Sbjct: 181 KYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPK 240

Query: 241 ASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDF 300
           ASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDF
Sbjct: 241 ASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDF 300

Query: 301 KGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVV 360
           KGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVV
Sbjct: 301 KGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVV 360

Query: 361 FQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFR 420
           FQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFR
Sbjct: 361 FQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFR 420

Query: 421 KGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDED 480
           KGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDED
Sbjct: 421 KGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDED 480

Query: 481 KMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGI 540
           KMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGI
Sbjct: 481 KMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGI 540

Query: 541 SLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSEN 600
           SLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSEN
Sbjct: 541 SLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSEN 600

Query: 601 SSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVS 660
           SSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVS
Sbjct: 601 SSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVS 660

Query: 661 SSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHPDAGKLGDPACPEIKIQLEASEQ 720
           SSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHPDAGKLGDPACPEIKIQLEASEQ
Sbjct: 661 SSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHPDAGKLGDPACPEIKIQLEASEQ 720

Query: 721 HMPQLGC 727
           HMPQLGC
Sbjct: 721 HMPQLGC 727


>gi|224809582 RAP1 GTPase activating protein isoform c [Homo
           sapiens]
          Length = 663

 Score = 1343 bits (3476), Expect = 0.0
 Identities = 663/663 (100%), Positives = 663/663 (100%)

Query: 65  MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN 124
           MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
Sbjct: 1   MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN 60

Query: 125 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV 184
           HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
Sbjct: 61  HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV 120

Query: 185 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL 244
           IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
Sbjct: 121 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL 180

Query: 245 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR 304
           IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
Sbjct: 181 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR 240

Query: 305 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE 364
           GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
Sbjct: 241 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE 300

Query: 365 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE 424
           NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
Sbjct: 301 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE 360

Query: 425 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN 484
           FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
Sbjct: 361 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN 420

Query: 485 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLIV 544
           GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLIV
Sbjct: 421 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLIV 480

Query: 545 PGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQ 604
           PGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQ
Sbjct: 481 PGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQ 540

Query: 605 SSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGT 664
           SSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGT
Sbjct: 541 SSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGT 600

Query: 665 PHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHPDAGKLGDPACPEIKIQLEASEQHMPQ 724
           PHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHPDAGKLGDPACPEIKIQLEASEQHMPQ
Sbjct: 601 PHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHPDAGKLGDPACPEIKIQLEASEQHMPQ 660

Query: 725 LGC 727
           LGC
Sbjct: 661 LGC 663


>gi|224809573 RAP1 GTPase activating protein isoform b [Homo
           sapiens]
          Length = 681

 Score = 1303 bits (3372), Expect = 0.0
 Identities = 655/689 (95%), Positives = 655/689 (95%), Gaps = 34/689 (4%)

Query: 65  MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN 124
           MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN
Sbjct: 1   MIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWIEGTN 60

Query: 125 HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV 184
           HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV
Sbjct: 61  HEITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDV 120

Query: 185 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL 244
           IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL
Sbjct: 121 IGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRL 180

Query: 245 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR 304
           IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR
Sbjct: 181 IVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFR 240

Query: 305 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE 364
           GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE
Sbjct: 241 GGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDE 300

Query: 365 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE 424
           NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE
Sbjct: 301 NTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPE 360

Query: 425 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN 484
           FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN
Sbjct: 361 FQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMMGLGGDEDKMEN 420

Query: 485 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGI---- 540
           GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGI    
Sbjct: 421 GSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLLI 480

Query: 541 ----------------------SLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE 578
                                 SLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE
Sbjct: 481 PGKSASRFGRRGSAIGIGTVEESLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRE 540

Query: 579 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS 638
           SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS
Sbjct: 541 SPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASS 600

Query: 639 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHP 698
           FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSS        P
Sbjct: 601 FASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSS--------P 652

Query: 699 DAGKLGDPACPEIKIQLEASEQHMPQLGC 727
           DAGKLGDPACPEIKIQLEASEQHMPQLGC
Sbjct: 653 DAGKLGDPACPEIKIQLEASEQHMPQLGC 681


>gi|156086724 GTPase activating Rap/RanGAP domain-like 4 isoform 1
           [Homo sapiens]
          Length = 730

 Score =  667 bits (1722), Expect = 0.0
 Identities = 368/716 (51%), Positives = 481/716 (67%), Gaps = 35/716 (4%)

Query: 1   MSGRKRSFTFGAYGGVDKSFTSRRSVWRSDGQNQHFPQALDLSRVNLVPSYTPSLYPKNT 60
           M GRKRS +FG +G +DK+  +   V + +  N       D     L P  T     K++
Sbjct: 1   MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRP---LSPPLTAPPTMKSS 57

Query: 61  DLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWI 120
           + FEM+EKMQG +++EQ+   P P K ++DYIPYPS+ EV+ + GP+P ++LPQFGGYWI
Sbjct: 58  EFFEMLEKMQGIKLEEQK---PGPQKNKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWI 114

Query: 121 EGTNH---------EITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDA 171
           E   +          I    E + L   T   KLEC   AR YR+HFLGK+H N+Y   +
Sbjct: 115 EDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGS 174

Query: 172 ALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVD 231
           +LG+L+ S+K +     E+LR++LR+K +T H+ IP++ L++ P+V Q+AK  C+D    
Sbjct: 175 SLGNLILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGL 234

Query: 232 RFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFL 291
           RF PVLYPKAS++IV++DEH ++N FKFGVIYQK  QT EEELF  NEESPAF EFL+ L
Sbjct: 235 RFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLL 294

Query: 292 GQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRH 351
           G  + LQDFKGFRGGLDVTHGQTG ESVY  FR++EIMFHVSTKLP+T+GDAQQLQRKRH
Sbjct: 295 GDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRH 354

Query: 352 IGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGP 411
           IGNDIVA++FQ+ENTPFVPDMIASNFLHAY+VVQ E  G + P YKVSVTAR+DVP FGP
Sbjct: 355 IGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGP 414

Query: 412 PLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQS 471
           PLP P VF+KGPEF+EFLLTKL NAE AC K++KFAKLE+RTRAALL+ L++ELH H+Q+
Sbjct: 415 PLPSPPVFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQA 474

Query: 472 MMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNT--VSTSHSGSFAP 529
           M+GLG +EDK ENG G GGF ESFKR IR RS SM+ M    KK ++  +  S SG  + 
Sbjct: 475 MLGLGPEEDKFENG-GHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISH 533

Query: 530 NNPDLAKAAGISLIV------PGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAG 583
           N+ ++ K      +V        +SP +++SG F    +   G E   + + + +S  + 
Sbjct: 534 NSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHT---GSEGQGDSRARCDSTSST 590

Query: 584 QKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVV 643
            KTPD GH SQE KSE SS  SSPE+    N+ +   +  E  +  SRSSSS SS +S  
Sbjct: 591 PKTPDGGHSSQEIKSETSSNPSSPEI--CPNKEKPFMKLKENGRAISRSSSSTSSVSSTA 648

Query: 644 EETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGP---SRSP 696
            E E ++  D+G  S  S+ +P K++ F+YS     S  + S G++  P   SRSP
Sbjct: 649 GEGEAMEEGDSG-GSQPSTTSPFKQEVFVYSP--SPSSESPSLGAAATPIIMSRSP 701


>gi|156086740 GTPase activating Rap/RanGAP domain-like 4 isoform 2
           [Homo sapiens]
          Length = 715

 Score =  647 bits (1669), Expect = 0.0
 Identities = 362/716 (50%), Positives = 470/716 (65%), Gaps = 50/716 (6%)

Query: 1   MSGRKRSFTFGAYGGVDKSFTSRRSVWRSDGQNQHFPQALDLSRVNLVPSYTPSLYPKNT 60
           M GRKRS +FG +G +DK+  +   V + +  N       D     L P  T     K++
Sbjct: 1   MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRP---LSPPLTAPPTMKSS 57

Query: 61  DLFEMIEKMQGSRMDEQRCSFPPPLKTEEDYIPYPSVHEVLGREGPFPLILLPQFGGYWI 120
           + FEM+EKMQ                  +DYIPYPS+ EV+ + GP+P ++LPQFGGYWI
Sbjct: 58  EFFEMLEKMQ------------------DDYIPYPSIDEVVEKGGPYPQVILPQFGGYWI 99

Query: 121 EGTNH---------EITSIPETEPLQSPTTKVKLECNPTARIYRKHFLGKEHFNYYSLDA 171
           E   +          I    E + L   T   KLEC   AR YR+HFLGK+H N+Y   +
Sbjct: 100 EDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRHFLGKDHLNFYCTGS 159

Query: 172 ALGHLVFSLKYDVIGDQEHLRLLLRTKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVD 231
           +LG+L+ S+K +     E+LR++LR+K +T H+ IP++ L++ P+V Q+AK  C+D    
Sbjct: 160 SLGNLILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGL 219

Query: 232 RFYPVLYPKASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFL 291
           RF PVLYPKAS++IV++DEH ++N FKFGVIYQK  QT EEELF  NEESPAF EFL+ L
Sbjct: 220 RFNPVLYPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLL 279

Query: 292 GQKVKLQDFKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRH 351
           G  + LQDFKGFRGGLDVTHGQTG ESVY  FR++EIMFHVSTKLP+T+GDAQQLQRKRH
Sbjct: 280 GDTITLQDFKGFRGGLDVTHGQTGVESVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRH 339

Query: 352 IGNDIVAVVFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGP 411
           IGNDIVA++FQ+ENTPFVPDMIASNFLHAY+VVQ E  G + P YKVSVTAR+DVP FGP
Sbjct: 340 IGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYKVSVTAREDVPTFGP 399

Query: 412 PLPDPAVFRKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQS 471
           PLP P VF+KGPEF+EFLLTKL NAE AC K++KFAKLE+RTRAALL+ L++ELH H+Q+
Sbjct: 400 PLPSPPVFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQA 459

Query: 472 MMGLGGDEDKMENGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNT--VSTSHSGSFAP 529
           M+GLG +EDK ENG G GGF ESFKR IR RS SM+ M    KK ++  +  S SG  + 
Sbjct: 460 MLGLGPEEDKFENG-GHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISH 518

Query: 530 NNPDLAKAAGISLIV------PGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAG 583
           N+ ++ K      +V        +SP +++SG F    +   G E   + + + +S  + 
Sbjct: 519 NSMEVTKTTFSPPVVAATVKNQSRSPIKRRSGLFPRLHT---GSEGQGDSRARCDSTSST 575

Query: 584 QKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVV 643
            KTPD GH SQE KSE SS  SSPE+    N+ +   +  E  +  SRSSSS SS +S  
Sbjct: 576 PKTPDGGHSSQEIKSETSSNPSSPEI--CPNKEKPFMKLKENGRAISRSSSSTSSVSSTA 633

Query: 644 EETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGP---SRSP 696
            E E ++  D+G  S  S+ +P K++ F+YS     S  + S G++  P   SRSP
Sbjct: 634 GEGEAMEEGDSG-GSQPSTTSPFKQEVFVYSP--SPSSESPSLGAAATPIIMSRSP 686


>gi|71143119 signal-induced proliferation-associated 1 like 3 [Homo
           sapiens]
          Length = 1781

 Score =  224 bits (572), Expect = 2e-58
 Identities = 128/338 (37%), Positives = 186/338 (55%), Gaps = 33/338 (9%)

Query: 151 ARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI------GDQEHLRLLLRTK------ 198
           AR Y+ +F+GKEH NY+ +D  LG +  S+K + +      G Q   R++ RT+      
Sbjct: 501 ARYYQDYFVGKEHANYFGVDEKLGPVAVSIKREKLEDHKEHGPQYQYRIIFRTRELITLR 560

Query: 199 ---------CRTYHDV---IPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLYPKASRLIV 246
                      T H     +P+    E+  V+    + C  + ++       PK +  ++
Sbjct: 561 GSILEDATPTATKHGTGRGLPLKDALEY--VIPELNIHCLRLALNT------PKVTEQLL 612

Query: 247 TFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGG 306
             DE  +    K G++Y K GQ+SEEE+++  E  PAF EFL  +G+KV L+ F  +   
Sbjct: 613 KLDEQGLCRKHKVGILYCKAGQSSEEEMYNNEEAGPAFEEFLSLIGEKVCLKGFTKYAAQ 672

Query: 307 LDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENT 366
           LDV    TGT S+Y  +++ EIMFHVST LPYT  + QQL RKRHIGNDIV ++FQ+   
Sbjct: 673 LDVKTDSTGTHSLYTMYQDYEIMFHVSTLLPYTPNNRQQLLRKRHIGNDIVTIIFQEPGA 732

Query: 367 -PFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEF 425
            PF P  I S+F H +++V+      D   Y ++VT   D P FGPP+P    FRK   F
Sbjct: 733 LPFTPKNIRSHFQHVFIIVRVHNPCTDNVCYSMAVTRSKDAPPFGPPIPSGTTFRKSDVF 792

Query: 426 QEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYE 463
           ++FLL K+INAE A +K++KF  +  RTR   L+ L E
Sbjct: 793 RDFLLAKVINAENAAHKSDKFHTMATRTRQEYLKDLAE 830


>gi|7662126 signal-induced proliferation-associated 1 like 1 [Homo
           sapiens]
          Length = 1804

 Score =  222 bits (565), Expect = 1e-57
 Identities = 128/331 (38%), Positives = 185/331 (55%), Gaps = 17/331 (5%)

Query: 151 ARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI------GDQEHLRLLLRT------K 198
           A  YRK F  KEH+NY+  D  LG +  S++ +        G   + R++ RT      +
Sbjct: 489 AYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPDEMKENGSPYNYRIIFRTSELMTLR 548

Query: 199 CRTYHDVIPISCLTEFPNVVQMAKL---VCEDVNVDRFYPVLY-PKASRLIVTFDEHVIS 254
                D IP +        + + ++   V  ++NV         PK +  ++  DE  ++
Sbjct: 549 GSVLEDAIPSTAKHSTARGLPLKEVLEHVVPELNVQCLRLAFNTPKVTEQLMKLDEQGLN 608

Query: 255 NNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHGQT 314
              K G++Y K GQ++EEE+++     PAF EFL+ LG++V+L+ F+ +R  LD     T
Sbjct: 609 YQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDST 668

Query: 315 GTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENT-PFVPDMI 373
           GT S+Y  +++ EIMFHVST LPYT  + QQL RKRHIGNDIV +VFQ+    PF P  I
Sbjct: 669 GTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNI 728

Query: 374 ASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLTKL 433
            S+F H +V+V+      D   Y V+VT   DVP FGPP+P    F K   F++FLL K+
Sbjct: 729 RSHFQHVFVIVRVHNPCSDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKV 788

Query: 434 INAEYACYKAEKFAKLEERTRAALLETLYEE 464
           INAE A +K+EKF  +  RTR   L+ L E+
Sbjct: 789 INAENAAHKSEKFRAMATRTRQEYLKDLAEK 819


>gi|112421013 signal-induced proliferation-associated 1 like 2 [Homo
           sapiens]
          Length = 1722

 Score =  221 bits (563), Expect = 2e-57
 Identities = 132/332 (39%), Positives = 182/332 (54%), Gaps = 20/332 (6%)

Query: 151 ARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI-------GDQEHLRLLLRTKCRT-- 201
           A  YRK F GKEH NY+ +D  LG +  S++ + +       G Q + R+  RT   T  
Sbjct: 484 AYYYRKFFYGKEHQNYFGIDENLGPVAVSIRREKVEDAKEKEGSQFNYRVAFRTSELTTL 543

Query: 202 ----YHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLY-----PKASRLIVTFDEHV 252
                 D IP +        + + K V E V  +     L      PK S  ++  DE  
Sbjct: 544 RGAILEDAIPSTARHGTARGLPL-KEVLEYVIPELSIQCLRQASNSPKVSEQLLKLDEQG 602

Query: 253 ISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHG 312
           +S   K G++Y K GQ++EEE+++     PAF EFL+ LGQ+V+L+ F  +R  LD    
Sbjct: 603 LSFQHKIGILYCKAGQSTEEEMYNNETAGPAFEEFLDLLGQRVRLKGFSKYRAQLDNKTD 662

Query: 313 QTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQDENT-PFVPD 371
            TGT S+Y  +++ E+MFHVST LPY   + QQL RKRHIGNDIV +VFQ+    PF P 
Sbjct: 663 STGTHSLYTTYKDYELMFHVSTLLPYMPNNRQQLLRKRHIGNDIVTIVFQEPGALPFTPK 722

Query: 372 MIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFLLT 431
            I S+F H +V+V+      +   Y V V+   DVP FGPP+P    F K   F++FLL 
Sbjct: 723 SIRSHFQHVFVIVKVHNPCTENVCYSVGVSRSKDVPPFGPPIPKGVTFPKSAVFRDFLLA 782

Query: 432 KLINAEYACYKAEKFAKLEERTRAALLETLYE 463
           K+INAE A +K+EKF  +  RTR   L+ L E
Sbjct: 783 KVINAENAAHKSEKFRAMATRTRQEYLKDLAE 814


>gi|207448705 GTPase activating Rap/RanGAP domain-like 3 [Homo
           sapiens]
          Length = 1013

 Score =  211 bits (536), Expect = 3e-54
 Identities = 129/336 (38%), Positives = 188/336 (55%), Gaps = 20/336 (5%)

Query: 141 TKVKLECNPT--ARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVIGDQE--HLRLLLR 196
           T V LE NP    R Y K+FLG+ H NY   DA       S+      +Q     R +L 
Sbjct: 85  TDVHLE-NPEYHTRWYFKYFLGQVHQNYIGNDAEKSPFFLSVTLSDQNNQRVPQYRAILW 143

Query: 197 TKCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYP----VLYPKASRLIVTFDEHV 252
            K  T    +P S     P      K +   +N+D+F      + +P+  + ++  +E  
Sbjct: 144 RKTGTQKICLPYS-----PTKTLSVKSILSAMNLDKFEKGPREIFHPEIQKDLLVLEEQE 198

Query: 253 ISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFKGFRGGLDVTHG 312
            S NFKFGV++ K GQ +++E+FS    S  F +FL  LG  + L+ + G+RGGLD  + 
Sbjct: 199 GSVNFKFGVLFAKDGQLTDDEMFSNEIGSEPFQKFLNLLGDTITLKGWTGYRGGLDTKND 258

Query: 313 QTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVFQ--DENTP-FV 369
            TG  SVY  ++  EIMFHVST LPY++ + QQ++RKRHIGNDIV +VFQ  +E++P F 
Sbjct: 259 TTGIHSVYTVYQGHEIMFHVSTMLPYSKENKQQVERKRHIGNDIVTIVFQEGEESSPAFK 318

Query: 370 PDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVFRKGPEFQEFL 429
           P MI S+F H + +V+      +   Y++ + + + VP FGPPLP P VF    EF++FL
Sbjct: 319 PSMIRSHFTHIFALVRYNQQNDN---YRLKIFSEESVPLFGPPLPTPPVFTDHQEFRDFL 375

Query: 430 LTKLINAEYACYKAEKFAKLEERTRAALLETLYEEL 465
           L KLIN E A  +   FA+   RT   L+ +L+++L
Sbjct: 376 LVKLINGEKATLETPTFAQKRRRTLDMLIRSLHQDL 411


>gi|206725526 signal-induced proliferation-associated protein 1
           [Homo sapiens]
          Length = 1042

 Score =  210 bits (535), Expect = 3e-54
 Identities = 132/342 (38%), Positives = 185/342 (54%), Gaps = 14/342 (4%)

Query: 134 EPLQSPTTKVKLE-CNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI-----GD 187
           E  Q+ T+   LE  +  A  YRK+F GKEH N++ +D +LG +  SL+ +       G 
Sbjct: 198 EEPQNRTSAYSLEHADLGAGYYRKYFYGKEHQNFFGMDESLGPVAVSLRREEKEGSGGGT 257

Query: 188 QEHLRLLLRT-KCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLY-----PKA 241
               R+++RT + RT    I    L   P      + + E V        L      PK 
Sbjct: 258 LHSYRVIVRTTQLRTLRGTISEDALPPGPPRGLSPRKLLEHVAPQLSPSCLRLGSASPKV 317

Query: 242 SRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFK 301
            R ++T DE V+S   K G++Y + GQ SEEE+++  E  PAF++FL  LG  V+L+ F+
Sbjct: 318 PRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAFMQFLTLLGDVVRLKGFE 377

Query: 302 GFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVF 361
            +R  LD     TGT S+Y  +++ EIMFHVST LPYT  + QQL RKRHIGNDIV +VF
Sbjct: 378 SYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQLLRKRHIGNDIVTIVF 437

Query: 362 QDENT-PFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLP-DPAVF 419
           Q+  + PF P  I S+F H ++VV+A         Y+V+V+   D P FGP LP     F
Sbjct: 438 QEPGSKPFCPTTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRTQDTPAFGPALPAGGGPF 497

Query: 420 RKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETL 461
               +F+ FLL K +N E A   A +F  +  RTR   L+ L
Sbjct: 498 AANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDL 539


>gi|206725523 signal-induced proliferation-associated protein 1
           [Homo sapiens]
          Length = 1042

 Score =  210 bits (535), Expect = 3e-54
 Identities = 132/342 (38%), Positives = 185/342 (54%), Gaps = 14/342 (4%)

Query: 134 EPLQSPTTKVKLE-CNPTARIYRKHFLGKEHFNYYSLDAALGHLVFSLKYDVI-----GD 187
           E  Q+ T+   LE  +  A  YRK+F GKEH N++ +D +LG +  SL+ +       G 
Sbjct: 198 EEPQNRTSAYSLEHADLGAGYYRKYFYGKEHQNFFGMDESLGPVAVSLRREEKEGSGGGT 257

Query: 188 QEHLRLLLRT-KCRTYHDVIPISCLTEFPNVVQMAKLVCEDVNVDRFYPVLY-----PKA 241
               R+++RT + RT    I    L   P      + + E V        L      PK 
Sbjct: 258 LHSYRVIVRTTQLRTLRGTISEDALPPGPPRGLSPRKLLEHVAPQLSPSCLRLGSASPKV 317

Query: 242 SRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQDFK 301
            R ++T DE V+S   K G++Y + GQ SEEE+++  E  PAF++FL  LG  V+L+ F+
Sbjct: 318 PRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAFMQFLTLLGDVVRLKGFE 377

Query: 302 GFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAVVF 361
            +R  LD     TGT S+Y  +++ EIMFHVST LPYT  + QQL RKRHIGNDIV +VF
Sbjct: 378 SYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQLLRKRHIGNDIVTIVF 437

Query: 362 QDENT-PFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLP-DPAVF 419
           Q+  + PF P  I S+F H ++VV+A         Y+V+V+   D P FGP LP     F
Sbjct: 438 QEPGSKPFCPTTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRTQDTPAFGPALPAGGGPF 497

Query: 420 RKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETL 461
               +F+ FLL K +N E A   A +F  +  RTR   L+ L
Sbjct: 498 AANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDL 539


>gi|118600961 akt substrate AS250 [Homo sapiens]
          Length = 1873

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 62/234 (26%), Positives = 107/234 (45%), Gaps = 19/234 (8%)

Query: 240  KASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQD 299
            K  R +   D        K  V Y   GQ  +  + S    S A+ +F+  LG +V L  
Sbjct: 1630 KLLRELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWEVDLST 1689

Query: 300  FKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAV 359
              GF GGL   +G TG  + Y      E++FHVST++P ++ D    ++ RH+GND V +
Sbjct: 1690 HCGFMGGLQ-RNGSTGQTAPYYATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHI 1747

Query: 360  VFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVF 419
            V+ + +  +   +I + F    +++          ++ +++T + +VPFFGP      V 
Sbjct: 1748 VWSEHSRDYRRGIIPTAFGDVSIIIYP----MKNHMFFIAITKKPEVPFFGPLFDGAIVS 1803

Query: 420  RKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYEELHIHSQSMM 473
             K       LL  L+ A   C  A +  K        L ++ YEE  ++ ++++
Sbjct: 1804 GK-------LLPSLVCA--TCINASRAVK----CLIPLYQSFYEERALYLEAII 1844


>gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2
            [Homo sapiens]
          Length = 2083

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 59/224 (26%), Positives = 99/224 (44%), Gaps = 8/224 (3%)

Query: 240  KASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQD 299
            K  R +   D        K  V Y   GQ  +  + +    S A+ +F+  LG +V L +
Sbjct: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850

Query: 300  FKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAV 359
              GF GGL   +  TG  + Y      E++FHVST++P ++ D    ++ RH+GND V +
Sbjct: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHI 1908

Query: 360  VFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVF 419
            V+ +    +   +I + F    +V+          ++ + +  + +VPFFG PL D A+ 
Sbjct: 1909 VWSEHTRDYRRGIIPTEFGDVLIVIYP----MKNHMFSIQIMKKPEVPFFG-PLFDGAIV 1963

Query: 420  RKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYE 463
              G      +    INA  A        +     RA  L+T+ +
Sbjct: 1964 -NGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQ 2006


>gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1
            [Homo sapiens]
          Length = 2036

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 59/224 (26%), Positives = 99/224 (44%), Gaps = 8/224 (3%)

Query: 240  KASRLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEESPAFVEFLEFLGQKVKLQD 299
            K  R +   D        K  V Y   GQ  +  + +    S A+ +F+  LG +V L +
Sbjct: 1791 KLLRELRNLDSRQCRETHKIAVFYVAEGQEDKHSILTNTGGSQAYEDFVAGLGWEVNLTN 1850

Query: 300  FKGFRGGLDVTHGQTGTESVYCNFRNKEIMFHVSTKLPYTEGDAQQLQRKRHIGNDIVAV 359
              GF GGL   +  TG  + Y      E++FHVST++P ++ D    ++ RH+GND V +
Sbjct: 1851 HCGFMGGLQ-KNKSTGLTTPYFATSTVEVIFHVSTRMP-SDSDDSLTKKLRHLGNDEVHI 1908

Query: 360  VFQDENTPFVPDMIASNFLHAYVVVQAEGGGPDGPLYKVSVTARDDVPFFGPPLPDPAVF 419
            V+ +    +   +I + F    +V+          ++ + +  + +VPFFG PL D A+ 
Sbjct: 1909 VWSEHTRDYRRGIIPTEFGDVLIVIYP----MKNHMFSIQIMKKPEVPFFG-PLFDGAIV 1963

Query: 420  RKGPEFQEFLLTKLINAEYACYKAEKFAKLEERTRAALLETLYE 463
              G      +    INA  A        +     RA  L+T+ +
Sbjct: 1964 -NGKVLPIMVRATAINASRALKSLIPLYQNFYEERARYLQTIVQ 2006


>gi|116256350 tuberous sclerosis 2 isoform 4 [Homo sapiens]
          Length = 1740

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 51/159 (32%), Positives = 82/159 (51%), Gaps = 11/159 (6%)

Query: 235  PVLYPKAS----RLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEE-SPAFVEFLE 289
            P+L P  S    R +   D+    +  K  V+Y   GQ++ E    +NE  S  + EFL 
Sbjct: 1450 PILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLT 1509

Query: 290  FLGQKVKLQDF---KGFRGGLDVTHGQTGTESVYCNFRN-KEIMFHVSTKLPYTEGDAQQ 345
             LG+ ++L+D    K + GGLDV  G+ G +  YC   +  + +FH++T +P  + D  +
Sbjct: 1510 GLGRLIELKDCQPDKVYLGGLDVC-GEDG-QFTYCWHDDIMQAVFHIATLMPTKDVDKHR 1567

Query: 346  LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVV 384
              +KRH+GND V++V+ D    F    I   F   +V+V
Sbjct: 1568 CDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIV 1606


>gi|116256352 tuberous sclerosis 2 isoform 1 [Homo sapiens]
          Length = 1807

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 51/159 (32%), Positives = 82/159 (51%), Gaps = 11/159 (6%)

Query: 235  PVLYPKAS----RLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEE-SPAFVEFLE 289
            P+L P  S    R +   D+    +  K  V+Y   GQ++ E    +NE  S  + EFL 
Sbjct: 1517 PILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLT 1576

Query: 290  FLGQKVKLQDF---KGFRGGLDVTHGQTGTESVYCNFRN-KEIMFHVSTKLPYTEGDAQQ 345
             LG+ ++L+D    K + GGLDV  G+ G +  YC   +  + +FH++T +P  + D  +
Sbjct: 1577 GLGRLIELKDCQPDKVYLGGLDVC-GEDG-QFTYCWHDDIMQAVFHIATLMPTKDVDKHR 1634

Query: 346  LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVV 384
              +KRH+GND V++V+ D    F    I   F   +V+V
Sbjct: 1635 CDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIV 1673


>gi|167412124 tuberous sclerosis 2 isoform 5 [Homo sapiens]
          Length = 1784

 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 51/159 (32%), Positives = 82/159 (51%), Gaps = 11/159 (6%)

Query: 235  PVLYPKAS----RLIVTFDEHVISNNFKFGVIYQKLGQTSEEELFSTNEE-SPAFVEFLE 289
            P+L P  S    R +   D+    +  K  V+Y   GQ++ E    +NE  S  + EFL 
Sbjct: 1494 PILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLT 1553

Query: 290  FLGQKVKLQDF---KGFRGGLDVTHGQTGTESVYCNFRN-KEIMFHVSTKLPYTEGDAQQ 345
             LG+ ++L+D    K + GGLDV  G+ G +  YC   +  + +FH++T +P  + D  +
Sbjct: 1554 GLGRLIELKDCQPDKVYLGGLDVC-GEDG-QFTYCWHDDIMQAVFHIATLMPTKDVDKHR 1611

Query: 346  LQRKRHIGNDIVAVVFQDENTPFVPDMIASNFLHAYVVV 384
              +KRH+GND V++V+ D    F    I   F   +V+V
Sbjct: 1612 CDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIV 1650


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 36/132 (27%), Positives = 60/132 (45%), Gaps = 13/132 (9%)

Query: 484 NGSGGGGFFESFKRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAK-AAGISL 542
           +GSG G  +       RSRS S+ ++   +   ++ S++HS        DLA   +  S 
Sbjct: 687 SGSGSGSSYSGSSS--RSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASS 744

Query: 543 IVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRES---PPAGQKTPDSGHVSQEPKSE 599
             P  + TRK+ G   S++      + ++E + KR+S   PP   K P  G  SQ+P + 
Sbjct: 745 RSPAPAQTRKEKGK--SKKE-----DGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTP 797

Query: 600 NSSTQSSPEMPT 611
             +    P+  T
Sbjct: 798 QQAPPGQPQQGT 809



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 36/156 (23%), Positives = 62/156 (39%), Gaps = 17/156 (10%)

Query: 571 QEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSS-------------PEMPTTKNRAE 617
           ++ +EK +  P  +        ++ PK E ++T                 + P  K    
Sbjct: 473 EKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVS 532

Query: 618 TAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLE-SVSSSGTPHKRDSFIYSTW 676
            +  RA   +  S SS+SAS+ +     +    G  +    S SSS + +   S  +S++
Sbjct: 533 VSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSF 592

Query: 677 LEDSVSTTSGGSSPGPSRSPHPDAGKL---GDPACP 709
                 + S  SSP PS +P P    +   G+PA P
Sbjct: 593 SGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPP 628



 Score = 33.9 bits (76), Expect = 0.55
 Identities = 48/201 (23%), Positives = 66/201 (32%), Gaps = 13/201 (6%)

Query: 501 SRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLIV---PGKSPTRKKSGPF 557
           SRS S    G S  +  + S S   S +  +   + +   S      P  SPT     P 
Sbjct: 559 SRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRP- 617

Query: 558 GSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAE 617
            S R+         +  EK    PA    P     +  P  E +     P     K R  
Sbjct: 618 -SIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKP-GDPREARRKERPA 675

Query: 618 TAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWL 677
               R   L      S S+ S +S    +  V    +   + SSS + H  DS       
Sbjct: 676 RTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDS------- 728

Query: 678 EDSVSTTSGGSSPGPSRSPHP 698
           ED  +  +   S   SRSP P
Sbjct: 729 EDMYADLASPVSSASSRSPAP 749


>gi|113415504 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 13/140 (9%)

Query: 558 GSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAE 617
           G ++ S +G++   +    R   P  +K           +S+  S   S +   TK  +E
Sbjct: 5   GVKKKSLLGVKENNKKSSTRAPSPTKRKD----------RSDEKSKDRSKDKGATKESSE 54

Query: 618 TAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWL 677
               R +  K  S SS S+S+ +     +       TG  S SSS +   R     S+  
Sbjct: 55  KDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSG---SSST 111

Query: 678 EDSVSTTSGGSSPGPSRSPH 697
             S S++S   SP PSR  H
Sbjct: 112 SRSSSSSSSSGSPSPSRRRH 131


>gi|169166499 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 13/140 (9%)

Query: 558 GSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAE 617
           G ++ S +G++   +    R   P  +K           +S+  S   S +   TK  +E
Sbjct: 5   GVKKKSLLGVKENNKKSSTRAPSPTKRKD----------RSDEKSKDRSKDKGATKESSE 54

Query: 618 TAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWL 677
               R +  K  S SS S+S+ +     +       TG  S SSS +   R     S+  
Sbjct: 55  KDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSG---SSST 111

Query: 678 EDSVSTTSGGSSPGPSRSPH 697
             S S++S   SP PSR  H
Sbjct: 112 SRSSSSSSSSGSPSPSRRRH 131


>gi|113415498 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 13/140 (9%)

Query: 558 GSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAE 617
           G ++ S +G++   +    R   P  +K           +S+  S   S +   TK  +E
Sbjct: 5   GVKKKSLLGVKENNKKSSTRAPSPTKRKD----------RSDEKSKDRSKDKGATKESSE 54

Query: 618 TAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWL 677
               R +  K  S SS S+S+ +     +       TG  S SSS +   R     S+  
Sbjct: 55  KDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSG---SSST 111

Query: 678 EDSVSTTSGGSSPGPSRSPH 697
             S S++S   SP PSR  H
Sbjct: 112 SRSSSSSSSSGSPSPSRRRH 131


>gi|88973230 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 3 [Homo sapiens]
          Length = 305

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 13/140 (9%)

Query: 558 GSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAE 617
           G ++ S +G++   +    R   P  +K           +S+  S   S +   TK  +E
Sbjct: 5   GVKKKSLLGVKENNKKSSTRAPSPTKRKD----------RSDEKSKDRSKDKGATKESSE 54

Query: 618 TAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWL 677
               R +  K  S SS S+S+ +     +       TG  S SSS +   R     S+  
Sbjct: 55  KDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSG---SSST 111

Query: 678 EDSVSTTSGGSSPGPSRSPH 697
             S S++S   SP PSR  H
Sbjct: 112 SRSSSSSSSSGSPSPSRRRH 131


>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 6 [Homo sapiens]
          Length = 305

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 13/140 (9%)

Query: 558 GSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAE 617
           G ++ S +G++   +    R   P  +K           +S+  S   S +   TK  +E
Sbjct: 5   GVKKKSLLGVKENNKKSSTRAPSPTKRKD----------RSDEKSKDRSKDKGATKESSE 54

Query: 618 TAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWL 677
               R +  K  S SS S+S+ +     +       TG  S SSS +   R     S+  
Sbjct: 55  KDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSG---SSST 111

Query: 678 EDSVSTTSGGSSPGPSRSPH 697
             S S++S   SP PSR  H
Sbjct: 112 SRSSSSSSSSGSPSPSRRRH 131


>gi|113415994 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 2 [Homo sapiens]
          Length = 305

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 13/140 (9%)

Query: 558 GSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAE 617
           G ++ S +G++   +    R   P  +K           +S+  S   S +   TK  +E
Sbjct: 5   GVKKKSLLGVKENNKKSSTRAPSPTKRKD----------RSDEKSKDRSKDKGATKESSE 54

Query: 618 TAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWL 677
               R +  K  S SS S+S+ +     +       TG  S SSS +   R     S+  
Sbjct: 55  KDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSG---SSST 111

Query: 678 EDSVSTTSGGSSPGPSRSPH 697
             S S++S   SP PSR  H
Sbjct: 112 SRSSSSSSSSGSPSPSRRRH 131


>gi|6857826 RNA-binding protein S1, serine-rich domain [Homo
           sapiens]
          Length = 305

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 13/140 (9%)

Query: 558 GSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAE 617
           G ++ S +G++   +    R   P  +K           +S+  S   S +   TK  +E
Sbjct: 5   GVKKKSLLGVKENNKKSSTRAPSPTKRKD----------RSDEKSKDRSKDKGATKESSE 54

Query: 618 TAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWL 677
               R +  K  S SS S+S+ +     +       TG  S SSS +   R     S+  
Sbjct: 55  KDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSG---SSST 111

Query: 678 EDSVSTTSGGSSPGPSRSPH 697
             S S++S   SP PSR  H
Sbjct: 112 SRSSSSSSSSGSPSPSRRRH 131


>gi|18379334 RNA-binding protein S1, serine-rich domain [Homo
           sapiens]
          Length = 305

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 13/140 (9%)

Query: 558 GSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAE 617
           G ++ S +G++   +    R   P  +K           +S+  S   S +   TK  +E
Sbjct: 5   GVKKKSLLGVKENNKKSSTRAPSPTKRKD----------RSDEKSKDRSKDKGATKESSE 54

Query: 618 TAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWL 677
               R +  K  S SS S+S+ +     +       TG  S SSS +   R     S+  
Sbjct: 55  KDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSG---SSST 111

Query: 678 EDSVSTTSGGSSPGPSRSPH 697
             S S++S   SP PSR  H
Sbjct: 112 SRSSSSSSSSGSPSPSRRRH 131


>gi|29570782 additional sex combs like 1 [Homo sapiens]
          Length = 1541

 Score = 40.4 bits (93), Expect = 0.006
 Identities = 53/201 (26%), Positives = 81/201 (40%), Gaps = 37/201 (18%)

Query: 542 LIVPGKS-------PTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPDSGHVSQ 594
           L VPG+S        TR++ G F  R    +     + + +K+ES  AG         S 
Sbjct: 386 LCVPGESVRIQRGPATRQRDGHFKKRSRPDLRTRARRNLYKKQESEQAGVAKDAKSVASD 445

Query: 595 EPKSENSSTQ------SSPEMPTTKNRA----------ETAAQRAEALKD-FSRSSSSAS 637
            P  ++   +      SSP +P T + A          E+ A R +A  D  +R+S+S  
Sbjct: 446 VPLYKDGEAKTDPAGLSSPHLPGTSSAAPDLEGPEFPVESVASRIQAEPDNLARASASPD 505

Query: 638 SFASVVEET---EGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSR 694
              S+ +ET   E  D +    E  +S+  P K+        LED  S  +   S   + 
Sbjct: 506 RIPSLPQETVDQEPKDQKRKSFEQAASASFPEKKPR------LEDRQSFRNTIESV-HTE 558

Query: 695 SPHPDAGKLGDPACPEIKIQL 715
            P P      +P  P I+IQL
Sbjct: 559 KPQPTK---EEPKVPPIRIQL 576


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 44/173 (25%), Positives = 64/173 (36%), Gaps = 17/173 (9%)

Query: 529  PNNPDLAKAAGISLIVPGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTPD 588
            P +PD A+A          S +        S  SS+ G E         E    G K  D
Sbjct: 2541 PKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSET--------EGEEEGDKNGD 2592

Query: 589  SG-HVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETE 647
             G        S  SS  +SP        A +++  + +    S SSSS+SS +S    + 
Sbjct: 2593 GGCGTGGRNCSAASSRAASP--------ASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644

Query: 648  GVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGPSRSPHPDA 700
                  +   S SSS +     S   ST  EDS  ++   ++P P+  P   A
Sbjct: 2645 SSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQA 2697



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 43/197 (21%), Positives = 67/197 (34%), Gaps = 15/197 (7%)

Query: 524  SGSFAPNNP-------DLAKAAGISLIVPG----KSPTRKKSGPFGSRRSSAIGIENIQE 572
            +GS  P  P       DLA+  G  L        KSP + ++   G+  S +    +   
Sbjct: 2508 AGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGS 2567

Query: 573  VQEKRESPPAGQKTPDSGHVSQEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRS 632
                  S  +G +T   G    +   +              +RA + A  + +    S S
Sbjct: 2568 SSSSSSSSSSGSET--EGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSS--SSS 2623

Query: 633  SSSASSFASVVEETEGVDGEDTGLESVSSSGTPHKRDSFIYSTWLEDSVSTTSGGSSPGP 692
            SSS+SS +S    +       +   S SSS +     S   S+    S +      S   
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDD 2683

Query: 693  SRSPHPDAGKLGDPACP 709
              +P P AG     A P
Sbjct: 2684 EAAPAPTAGPSAQAALP 2700


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 39.7 bits (91), Expect = 0.010
 Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 9/96 (9%)

Query: 545 PGKSPTRKKSGPFGSRRSSAIGIENIQEVQEKRESPPAGQKTP-DSGHVSQEPKSENSST 603
           P K  ++KK G +      A   E+ Q V+EK +      KTP  S H +++ K   SS+
Sbjct: 126 PLKKDSKKKGGSY------ATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSS 179

Query: 604 QSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSF 639
           +++PE   +K  ++  +Q+ +  KD   S  + + F
Sbjct: 180 ETNPESQNSKTVSKNCSQKDK--KDSKNSKKTNTEF 213


>gi|20070163 voltage-dependent calcium channel alpha 1G subunit
            isoform 1 [Homo sapiens]
          Length = 2377

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 13/174 (7%)

Query: 496  KRVIRSRSQSMDAMGLSNKKPNTVSTSHSGSFAPNNPDLAKAAGISLIVPGKSPTRKKSG 555
            +R   S S    A       P+  S+ HS   A ++    +++  SL   G++P+ K+  
Sbjct: 1067 RRTSSSGSAEPGAAHEMKSPPSARSSPHSPWSAASSWTSRRSSRNSL---GRAPSLKRRS 1123

Query: 556  PFGSRRSSAIG----IENIQEVQEKRESPPAGQKTPDSGHVSQEPKS--ENSSTQSSPEM 609
            P G RRS   G     ++ +E  E+  + PAG      G + +E KS  +   T   P +
Sbjct: 1124 PSGERRSLLSGEGQESQDEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGL 1183

Query: 610  PTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGEDTGLESVSSSG 663
              T +   +A++     +D +  S+S     ++  +   +DG+D   E   S G
Sbjct: 1184 HRTASGRGSASEH----QDCNGKSASGRLARALRPDDPPLDGDDADDEGNLSKG 1233


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,535,639
Number of Sequences: 37866
Number of extensions: 1552365
Number of successful extensions: 5402
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 177
Number of HSP's that attempted gapping in prelim test: 5016
Number of HSP's gapped (non-prelim): 450
length of query: 727
length of database: 18,247,518
effective HSP length: 110
effective length of query: 617
effective length of database: 14,082,258
effective search space: 8688753186
effective search space used: 8688753186
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.