BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|224809412 myocyte enhancer factor 2B isoform a [Homo sapiens] (368 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|224809412 myocyte enhancer factor 2B isoform a [Homo sapiens] 771 0.0 gi|5174543 myocyte enhancer factor 2B isoform b [Homo sapiens] 540 e-154 gi|19923215 myocyte enhancer factor 2C isoform 1 [Homo sapiens] 191 9e-49 gi|196114945 myocyte enhancer factor 2C isoform 2 [Homo sapiens] 184 1e-46 gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens] 181 7e-46 gi|195972799 myocyte enhancer factor 2A isoform 1 [Homo sapiens] 180 2e-45 gi|5174545 myocyte enhancer factor 2D [Homo sapiens] 180 2e-45 gi|146134388 YLP motif containing 1 [Homo sapiens] 74 2e-13 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 71 2e-12 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 69 5e-12 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 69 5e-12 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 69 5e-12 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 69 9e-12 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 68 1e-11 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 67 3e-11 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 66 6e-11 gi|47132519 Ras association and pleckstrin homology domains 1 is... 66 6e-11 gi|163965366 nascent polypeptide-associated complex alpha subuni... 66 6e-11 gi|160707881 formin 2 [Homo sapiens] 65 1e-10 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 65 1e-10 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 65 1e-10 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 64 2e-10 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 64 2e-10 gi|11386183 WAS protein family, member 2 [Homo sapiens] 64 2e-10 gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 64 2e-10 gi|110832843 TBP-associated factor 4 [Homo sapiens] 64 3e-10 gi|19924099 synapsin I isoform Ia [Homo sapiens] 64 3e-10 gi|19924097 synapsin I isoform Ib [Homo sapiens] 64 3e-10 gi|14249150 single stranded DNA binding protein 4 isoform a [Hom... 63 4e-10 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 63 5e-10 >gi|224809412 myocyte enhancer factor 2B isoform a [Homo sapiens] Length = 368 Score = 771 bits (1992), Expect = 0.0 Identities = 368/368 (100%), Positives = 368/368 (100%) Query: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST Sbjct: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60 Query: 61 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG 120 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG Sbjct: 61 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG 120 Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP Sbjct: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT Sbjct: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240 Query: 241 PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLG 300 PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLG Sbjct: 241 PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLG 300 Query: 301 EEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRL 360 EEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRL Sbjct: 301 EEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRL 360 Query: 361 PLADGWPR 368 PLADGWPR Sbjct: 361 PLADGWPR 368 >gi|5174543 myocyte enhancer factor 2B isoform b [Homo sapiens] Length = 365 Score = 540 bits (1392), Expect = e-154 Identities = 281/350 (80%), Positives = 282/350 (80%), Gaps = 18/350 (5%) Query: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST Sbjct: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60 Query: 61 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG 120 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG Sbjct: 61 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG 120 Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP Sbjct: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT Sbjct: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240 Query: 241 PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPS------RGDGPPAV----- 289 PGPPLGSFPFLPGGPP P PP P S R G PA Sbjct: 241 PGPPLGSFPFLPGGPPVGAEAWARRVPQPAAPPRRPPQSASSLSASLRPPGAPATFLRPS 300 Query: 290 ---SSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKT 336 S P +SL GPP G PT R SP P P T Sbjct: 301 PIPCSSPGPWQSLCGLGPPCAGCPWPTAGPG----RRSPGGTSPERSPGT 346 >gi|19923215 myocyte enhancer factor 2C isoform 1 [Homo sapiens] Length = 473 Score = 191 bits (485), Expect = 9e-49 Identities = 130/323 (40%), Positives = 174/323 (53%), Gaps = 27/323 (8%) Query: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60 MGRKKIQI+RI+D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNS N+LFQYAST Sbjct: 1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYAST 60 Query: 61 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEG---PEEPGEKFRRL 116 DMD+VLLKYTEY+EPHESRTN+DI+ETL+++G+ G D P+ + D+ E +K+R++ Sbjct: 61 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKI 120 Query: 117 AGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPS-PFRPAAP 175 E D + R RL A+PPP + + ++P S S + Sbjct: 121 -NEDIDLMISRQRLC--------------AVPPPNFE---MPVSIPVSSHNSLVYSNPVS 162 Query: 176 KAGPPGLVHPLFSPSHLTSKTPPPL--YLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQ 233 G P L+ PL PS + P + P+ G L GG G + + Sbjct: 163 SLGNPNLL-PLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRN 221 Query: 234 NPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQP 293 +P +PG + P G+ + P +L PP PS + + +Q Sbjct: 222 SPGLLVSPGNLNKNMQAKSPPPMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVDLLLNQR 281 Query: 294 -SGGRSLGEEGPPTRGASPPTPP 315 + +S P + PT P Sbjct: 282 INNSQSAQSLATPVVSVATPTLP 304 >gi|196114945 myocyte enhancer factor 2C isoform 2 [Homo sapiens] Length = 463 Score = 184 bits (467), Expect = 1e-46 Identities = 149/404 (36%), Positives = 194/404 (48%), Gaps = 71/404 (17%) Query: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60 MGRKKIQI+RI+D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNS N+LFQYAST Sbjct: 1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYAST 60 Query: 61 DMDRVLLKYTEYSEPHESRTNTDILETL-KRRGIGLDGPE------LEP--DEGPEEPGE 111 DMD+VLLKYTEY+EPHESRTN+DI+E L K+ G + P+ L P +E ++ E Sbjct: 61 DMDKVLLKYTEYNEPHESRTNSDIVEALNKKENKGCESPDPDSSYALTPRTEEKYKKINE 120 Query: 112 KFRRLAGEGGDPALP----------------------------RPRLYPAA-PAMP---- 138 +F + PA+P P L P A P++ Sbjct: 121 EFDNMIKSHKIPAVPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLPLAHPSLQRNSM 180 Query: 139 SPDVVYGALPPPGCDPSGL--GEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKT 196 SP V + PP + GL G+ + P+ P LV P ++ +K+ Sbjct: 181 SPGVTH--RPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRNSPGLLVSPGNLNKNMQAKS 238 Query: 197 PPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSF--PFLP-- 252 PPP+ L R+ DL + P G NT S+ + N S + P+ S P LP Sbjct: 239 PPPMNLGMNNRKPDL--RVLIPPGSKNTMPSVNQRINNSQSAQSLATPVVSVATPTLPGQ 296 Query: 253 --GGPP---------EYGLGDPP-------PPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294 GG P EY L L ++ WQ P + Sbjct: 297 GMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQL 356 Query: 295 GGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFP 338 G + + + P T ++IKSE +SP P P +P Sbjct: 357 GACTSTHLSQSSNLSLPSTQSLNIKSEPVSP-PRDRTTTPSRYP 399 >gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens] Length = 497 Score = 181 bits (460), Expect = 7e-46 Identities = 123/293 (41%), Positives = 161/293 (54%), Gaps = 29/293 (9%) Query: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60 MGRKKIQI+RI+D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNS+N+LFQYAST Sbjct: 1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 60 Query: 61 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEGPEEP--GEKFRRLA 117 DMD+VLLKYTEY+EPHESRTN+DI+ETL+++G+ G + P+ + D P ++F +L Sbjct: 61 DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDAD-DYFEHSPLSEDRFSKL- 118 Query: 118 GEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKA 177 E D R P +P P ++ P P+ L P S SP A+ Sbjct: 119 NEDSDFIFKR-----GPPGLP-PQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTL 172 Query: 178 GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL--------PGGL-AGPRG-GLNTSRS 227 ++ P + H P P+ G + P G + P G G SR+ Sbjct: 173 TDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRA 232 Query: 228 L--------YSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQP 272 + L T +P PP G + P+ + PP G++ P Sbjct: 233 SPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPP 285 >gi|195972799 myocyte enhancer factor 2A isoform 1 [Homo sapiens] Length = 499 Score = 180 bits (456), Expect = 2e-45 Identities = 123/294 (41%), Positives = 159/294 (54%), Gaps = 29/294 (9%) Query: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60 MGRKKIQI+RI+D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNS+N+LFQYAST Sbjct: 1 MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 60 Query: 61 DMDRVLLKYTEYSEPHESRTNTDILETL-KRRGIGLDGPELEPDEG---PEEPGEKFRRL 116 DMD+VLLKYTEY+EPHESRTN+DI+E L K+ G D P +PD EK++++ Sbjct: 61 DMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSP--DPDTSYVLTPHTEEKYKKI 118 Query: 117 AGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPK 176 E + R + AP +P P ++ P P+ L P S SP A+ Sbjct: 119 NEEFDN----MMRNHKIAPGLP-PQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASST 173 Query: 177 AGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL--------PGGL-AGPRG-GLNTSR 226 ++ P + H P P+ G + P G + P G G SR Sbjct: 174 LTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSR 233 Query: 227 SL--------YSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQP 272 + + L T +P PP G + P+ + PP G++ P Sbjct: 234 ASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPP 287 >gi|5174545 myocyte enhancer factor 2D [Homo sapiens] Length = 521 Score = 180 bits (456), Expect = 2e-45 Identities = 171/468 (36%), Positives = 204/468 (43%), Gaps = 130/468 (27%) Query: 1 MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60 MGRKKIQI RI D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFN +N+LFQYAST Sbjct: 1 MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60 Query: 61 DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEGPEEP---GEKFRRL 116 DMD+VLLKYTEY+EPHESRTN DI+ETL+++G G D PE + ++ E+ +K+RR Sbjct: 61 DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRR- 119 Query: 117 AGEGGDPALPRPRLYPAAPAMPSPDVV-------------YGALPPPG------CDPSGL 157 A E D R AP P V G+L P DP L Sbjct: 120 ASEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLL 179 Query: 158 GEALPAQSRPS-----PFRPAAPKA-------------------------GPPGLVHPLF 187 PA R S P RPA+ A PGL+ P+ Sbjct: 180 SPQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLL-PVA 238 Query: 188 SPSHLT----SKTPPP----LYLPTEGRRSDLPGGLAGPRGG-----------------L 222 + + L +K+PPP L R+ DL + G L Sbjct: 239 NGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRL 298 Query: 223 NTSRSLYSGLQNPCSTATP-----GPPLGSFPFL--------------------PGG--- 254 S+S +S S ATP G P S P PGG Sbjct: 299 GVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSL 358 Query: 255 ----------PPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ--PSGGRSLGEE 302 P+ PP QP P QP + PP S P +L Sbjct: 359 GNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPG 418 Query: 303 GP-PTRGAS---PPTPPVSIKSERL------SPAPGGPGDFPKTFPYP 340 P P GA+ P +SIKSE + SPAP P FP P P Sbjct: 419 SPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEP 466 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 74.3 bits (181), Expect = 2e-13 Identities = 73/254 (28%), Positives = 101/254 (39%), Gaps = 53/254 (20%) Query: 123 PALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGL 182 P +P P L P+ P P + +PPPG P + +LP P P+ AGPP Sbjct: 531 PTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPP-- 588 Query: 183 VHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPG 242 P+ P L+S PPP+ P P ++T Sbjct: 589 --PVLPPPSLSSAGPPPVLPP-------------------------------PSLSSTAP 615 Query: 243 PPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ----PSGGRS 298 PP+ P L P G+ PPPG+ P P Q + PPA SSQ P R Sbjct: 616 PPVMPLPPLSSATPPPGI----PPPGV---PQGIPPQLTAAPVPPASSSQSSQVPEKPRP 668 Query: 299 LGEEGPPTRGASPPT---PPVSI--KSERL-SPAPGGPGDFP-KTFPYPLLLARSLAEPL 351 P + G++PPT PP+ SE++ S AP P +F L S A P Sbjct: 669 ALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPS 728 Query: 352 RPGPALRRLPLADG 365 +P A++ +P+ G Sbjct: 729 QPITAVKDMPVRSG 742 Score = 53.1 bits (126), Expect = 4e-07 Identities = 77/293 (26%), Positives = 107/293 (36%), Gaps = 50/293 (17%) Query: 116 LAGEGGDPALPRPRLYPAA--PAMPSPDV-------------VYGALPPPGCDPSGLGEA 160 L+ G P LP P L A P +P P + + A PPPG P G+ + Sbjct: 582 LSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQG 641 Query: 161 LPAQSRPSPFRPAAPKAGP--PGLVHPLFSPSHLT-SKTPPPLYLPTEGRRSDLPGGLAG 217 +P Q +P PA+ P P P+ ++ PP Y P +S P Sbjct: 642 IPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPP--LQSAGPSEQVN 699 Query: 218 PRGGLNTSRSLYSGLQNPC----STATPGPPLGSFPFLP---GG----PPEYGLGDPPPP 266 + L+ S YS + S+A P P+ + +P GG PP + P Sbjct: 700 SKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRG 759 Query: 267 PGLLQPPTL----APWQPSRGDGPPAVSSQPSGGRSLGE----EGPPTRGASPPTPPVS- 317 P P + + R GP ++P G R E EG ++ P P S Sbjct: 760 PRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQ 819 Query: 318 ---IKSERLSPAPGGP---GDFPKTFPYPLLLARSLAEPLRPGPALRRLPLAD 364 S LSP GP G P +S AEPL + + PLAD Sbjct: 820 FYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPL----SGNKEPLAD 868 Score = 42.7 bits (99), Expect = 5e-04 Identities = 39/123 (31%), Positives = 50/123 (40%), Gaps = 19/123 (15%) Query: 241 PGPPLGSFPFLPGGPPEYGLGD--PPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ---PSG 295 P PPL P +PGG G GD PPPPP P +Q + + Q P G Sbjct: 82 PPPPLPPPPVMPGG----GYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137 Query: 296 GRSLGEEGPPTRGASPPTPPVSI--KSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRP 353 + E PP SPP PP S S+ P P P + YP ++ P +P Sbjct: 138 LVPMELESPP---ESPPVPPGSYMPPSQSYMPPPQPPPSY-----YPPTSSQPYLPPAQP 189 Query: 354 GPA 356 P+ Sbjct: 190 SPS 192 Score = 37.7 bits (86), Expect = 0.017 Identities = 65/249 (26%), Positives = 79/249 (31%), Gaps = 59/249 (23%) Query: 131 YPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGP----------- 179 Y + P P V PPP P L EA P S PAAP + Sbjct: 8 YGGSSHYPPPPV-----PPP--PPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQ 60 Query: 180 --------PGLVHPLFSPSHLTSKT-PPPLYLPTEGRRSDLPGGLA-----GPRGGLNTS 225 + + P HL PPP +P G P GP Sbjct: 61 LQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ 120 Query: 226 RSLYSGLQNPCSTATPG-------PPLGSFPFLPGG--PPEYGLGDPPPPPGLLQPPT-- 274 + + + PG P S P PG PP PP PP PPT Sbjct: 121 QQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS 180 Query: 275 ---LAPWQPSRGDGP---------PAVSSQPSGGRSL---GEEGPPTRGASPPTPPVS-I 318 L P QPS P P+ SS S +S + P+ ASP P Sbjct: 181 QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS 240 Query: 319 KSERLSPAP 327 KS+ L+P P Sbjct: 241 KSQLLAPPP 249 Score = 36.6 bits (83), Expect = 0.037 Identities = 32/107 (29%), Positives = 41/107 (38%), Gaps = 18/107 (16%) Query: 255 PPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTP 314 PP PPP + PP L P P P ++ P G PP PP+ Sbjct: 518 PPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMP-----PP---VMPPSL 569 Query: 315 PVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAE----PLRPGPAL 357 P S+ P PG P P P+L SL+ P+ P P+L Sbjct: 570 PTSV------PPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSL 610 Score = 35.0 bits (79), Expect = 0.11 Identities = 57/213 (26%), Positives = 74/213 (34%), Gaps = 42/213 (19%) Query: 125 LPRPRLYPAAPAMPSPDVVYGAL-PPPGCDPSGLGEALPAQSRPSPFRPAA--PKAGPPG 181 LP P L P P MP YG PPP P G AL Q + + GPPG Sbjct: 81 LPPPPL-PPPPVMPGGG--YGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137 Query: 182 LVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATP 241 LV + PP Y+P +S +P P S Y Sbjct: 138 LVPMELESPPESPPVPPGSYMPPS--QSYMPPPQPPP--------SYY------------ 175 Query: 242 GPPLGSFPFLPGGPPEYGLGDPPPPPGLLQP-PTLAPWQPSRGD----------GPPAVS 290 PP S P+LP P + PP L P P+ + S A Sbjct: 176 -PPTSSQPYLP--PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP 232 Query: 291 SQPSGGRSLGEEGPPTRGASPPTPPVSIKSERL 323 S+PS G S + P ++PP +++ E L Sbjct: 233 SRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPL 265 Score = 33.5 bits (75), Expect = 0.31 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 5/38 (13%) Query: 132 PAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSP 169 P+AP +P P V + ++PPPG P G +P S+P P Sbjct: 1603 PSAPVLPPPPV-HSSIPPPGPVPMG----MPPMSKPPP 1635 Score = 32.7 bits (73), Expect = 0.53 Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 6/65 (9%) Query: 252 PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASP 311 PG P G PPPP G P R PPA SS P + PP P Sbjct: 1503 PGMYPPPGSYRPPPPMG------KPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLP 1556 Query: 312 PTPPV 316 P PPV Sbjct: 1557 PPPPV 1561 Score = 30.8 bits (68), Expect = 2.0 Identities = 38/170 (22%), Positives = 56/170 (32%), Gaps = 31/170 (18%) Query: 125 LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALP------AQSRPSPFRPAAPKAG 178 LP + P+ P+ A PPP P A+++ + + AAP+ Sbjct: 225 LPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPD 284 Query: 179 P----PGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQN 234 P P + HL S + + LPG GP +T + + Sbjct: 285 PSTMTPQEQQQYWYRQHLLSLQ--------QRTKVHLPGHKKGPVVAKDTPEPVKEEVTV 336 Query: 235 PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD 284 P ++ P P P P PPP PP L P +P D Sbjct: 337 PATSQVPESPSSEEP-------------PLPPPNEEVPPPLPPEEPQSED 373 Score = 30.4 bits (67), Expect = 2.6 Identities = 44/187 (23%), Positives = 66/187 (35%), Gaps = 38/187 (20%) Query: 108 EPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRP 167 E E+ +++ G +P + L P + + G PPPG Sbjct: 1468 EQKEQLQKMKDFGSEPQMA-DHLPPQESRLQNTSSRPGMYPPPGS--------------- 1511 Query: 168 SPFRPAAPKAGPPG-LVHPLFSPSHLT-SKTPPPLYLPTEGRRSDLP----------GGL 215 +RP P PPG +V P P+ + T PP+ +P LP + Sbjct: 1512 --YRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAV 1569 Query: 216 AGPRGGLNTSRSLY-----SGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLL 270 R ++ L+ GL + + T P S P LP PP + PP P + Sbjct: 1570 EQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIP--SAPVLP-PPPVHSSIPPPGPVPMG 1626 Query: 271 QPPTLAP 277 PP P Sbjct: 1627 MPPMSKP 1633 Score = 30.4 bits (67), Expect = 2.6 Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 22/133 (16%) Query: 231 GLQNPCSTATPGPPLGSFP---FLPGGPPEYG----------LGDPPPPPGLLQPPTLAP 277 G+ P + P PP+G P P PP + PPPPP L PP + Sbjct: 1504 GMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIK 1563 Query: 278 WQPS-----RGDGPPAV----SSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPG 328 Q S R D ++ G S + ++P PP + S P P Sbjct: 1564 PQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPV 1623 Query: 329 GPGDFPKTFPYPL 341 G P + P P+ Sbjct: 1624 PMGMPPMSKPPPV 1636 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 70.9 bits (172), Expect = 2e-12 Identities = 67/207 (32%), Positives = 76/207 (36%), Gaps = 24/207 (11%) Query: 123 PALPRPRLYPAAPAMPSPDVVY-GALPPPGCDPSGLGEALPAQSRPSPFRPAA-----PK 176 P+ P P + +P P + G+ PPP P L +P P P P A P Sbjct: 218 PSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPS 277 Query: 177 AGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRS-----DLPGGLAGPRGGLNTSRSLYSG 231 AG PG HP SH PP +P G P GL P G S Sbjct: 278 AGTPGAGHPGHGHSH--PHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGG-QPP 334 Query: 232 LQNPCSTATPGPPLGSFPFLPGGPP---EYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPA 288 + P PGPP P P GPP G P PP G+ PP L P P GPP Sbjct: 335 PRPPPGMPHPGPPPMGMP--PRGPPFGSPMGHPGPMPPHGMRGPPPLMP--PHGYTGPP- 389 Query: 289 VSSQPSGGRSLGEEGPPTRGASPPTPP 315 P G G PP PP PP Sbjct: 390 --RPPPYGYQRGPLPPPRPTPRPPVPP 414 Score = 55.1 bits (131), Expect = 1e-07 Identities = 69/231 (29%), Positives = 79/231 (34%), Gaps = 82/231 (35%) Query: 135 PAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAA-----PKAGPPGLVHPLFSP 189 P MP P +PPPG P G+ A+P P P P A P AG PG HP Sbjct: 235 PGMPPPGSFPPPVPPPGALPPGIPPAMP----PPPMPPGAAGHGPPSAGTPGAGHPGHGH 290 Query: 190 SHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATP--GPPLGS 247 SH P P PGG+ P G++ + + G P P GPP GS Sbjct: 291 SH-----PHPFP----------PGGM--PHPGMSQMQLAHHG---PHGLGHPHAGPP-GS 329 Query: 248 FPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTR 307 GG P P PPPG+ P GPP Sbjct: 330 -----GGQPP-----PRPPPGMPHP------------------------------GPPPM 349 Query: 308 GASPPTPPVSIKSERLSPAPGGPGDFP---KTFPYPLLLARSLAEPLRPGP 355 G P PP SP G PG P P PL+ P RP P Sbjct: 350 GMPPRGPPFG------SPM-GHPGPMPPHGMRGPPPLMPPHGYTGPPRPPP 393 Score = 53.5 bits (127), Expect = 3e-07 Identities = 56/192 (29%), Positives = 64/192 (33%), Gaps = 41/192 (21%) Query: 123 PALPRPRLYPAA--PAMPSPDVVYGALP--PPGCDPSGLGEALPAQSRPSPFRPAA---- 174 P +P P P PAMP P + GA PP G G S P PF P Sbjct: 245 PPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHP 304 Query: 175 -----------------PKAGPPGL--VHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGL 215 P AGPPG P P + PPP+ +P G P G Sbjct: 305 GMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGH 364 Query: 216 AGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPP-PPPGLLQPPT 274 GP G++ P P G P PP YG P PPP P Sbjct: 365 PGPMPP--------HGMRGPPPLMPPHGYTG-----PPRPPPYGYQRGPLPPPRPTPRPP 411 Query: 275 LAPWQPSRGDGP 286 + P P RG P Sbjct: 412 VPPRGPLRGPLP 423 Score = 36.2 bits (82), Expect = 0.048 Identities = 35/114 (30%), Positives = 38/114 (33%), Gaps = 7/114 (6%) Query: 105 GPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQ 164 GP G G GG P PRP P MP P +PP G P G P Sbjct: 315 GPHGLGHPHAGPPGSGGQPP-PRP-----PPGMPHPGPPPMGMPPRG-PPFGSPMGHPGP 367 Query: 165 SRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGP 218 P R P P G P P + + P P PT G L GP Sbjct: 368 MPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGP 421 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 69.3 bits (168), Expect = 5e-12 Identities = 75/224 (33%), Positives = 85/224 (37%), Gaps = 36/224 (16%) Query: 126 PRPRLYPAAPAM-----PSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 PR + P AP P P LP P P S PSPF A PP Sbjct: 359 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP-----PHLSGPSPFSMNANLPPPP 413 Query: 181 GLVHPLFSPS--HLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSL----YSGLQN 234 L PL S S H S PPPL L + + LP A P G L S++L S Sbjct: 414 AL-KPLSSLSTHHPPSAHPPPLQLMPQSQ--PLPSSPAQPPG-LTQSQNLPPPPASHPPT 469 Query: 235 PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294 P PP PF+PGGPP PP P PP P PP + S Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPA----GPGTSAQPPCSGAAAS 522 Query: 295 GGRSLGEEGPPTRGASPPTPPVSIKSERLSPA--PGGPGDFPKT 336 GG G G+S P P V IK E L A P P P++ Sbjct: 523 GGSIAG-------GSSCPLPTVQIKEEALDDAEEPESPPPPPRS 559 Score = 44.3 bits (103), Expect = 2e-04 Identities = 68/257 (26%), Positives = 89/257 (34%), Gaps = 28/257 (10%) Query: 123 PAL-PRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPG 181 PAL P+ P P PSP L PS A P P P + +AGP Sbjct: 250 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL- 308 Query: 182 LVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGG----LAGPRGGLN--TSRSLYSGLQNP 235 L HP P P LP + + P G A P L S+S Q P Sbjct: 309 LQHP---------GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 359 Query: 236 CSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQP--SRGDGPPAVSSQP 293 P PL P PP + P P PP L+ P + PP + +P Sbjct: 360 REQPLPPAPLAMPHIKP--PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 417 Query: 294 SGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTF---PYPLLLARSLAEP 350 SL PP+ A PP + +S+ L +P P ++ P P + Sbjct: 418 LS--SLSTHHPPS--AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 473 Query: 351 LRPGPALRRLPLADGWP 367 + P P + P G P Sbjct: 474 VAPQPPFAQHPFVPGGP 490 Score = 43.1 bits (100), Expect = 4e-04 Identities = 71/254 (27%), Positives = 89/254 (35%), Gaps = 52/254 (20%) Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 G P LP P P+A A+P P G A A ++P P AP Sbjct: 203 GTPQLPTPGPTPSATAVP---------------PQGSPTASQAPNQPQ--APTAPVPHTH 245 Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240 P P S PPP P L G P + L+ Q P Sbjct: 246 IQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHG--QGP----- 297 Query: 241 PGP-PLGSFPFL--PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGP----PAVSSQ- 292 PGP L + P L PG P +GL PP + Q G P P S Q Sbjct: 298 PGPHSLQAGPLLQHPGPPQPFGL-----------PPQASQGQAPLGTSPAAAYPHTSLQL 346 Query: 293 PSGGRSLGEEGPPTRGASPPTPPV--SIKSERLSPAPGGPGDFPKTFPYPLLLAR----S 346 P+ +L + PP PP P IK +P P P P+ +P L+ S Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA--PQAHKHPPHLSGPSPFS 404 Query: 347 LAEPLRPGPALRRL 360 + L P PAL+ L Sbjct: 405 MNANLPPPPALKPL 418 Score = 35.4 bits (80), Expect = 0.082 Identities = 50/162 (30%), Positives = 61/162 (37%), Gaps = 43/162 (26%) Query: 125 LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVH 184 +P+ + P++PA P LPPP PA P+ AP+ PP H Sbjct: 437 MPQSQPLPSSPAQPPGLTQSQNLPPP-----------PASHPPTGLHQVAPQ--PPFAQH 483 Query: 185 PLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCS--TATPG 242 P F P PPP+ PT S P AGP + Q PCS A+ G Sbjct: 484 P-FVPG-----GPPPITPPTCPSTSTPP---AGPG----------TSAQPPCSGAAASGG 524 Query: 243 PPLG--SFPFLPGGPPEYGLGD------PPPPPGLLQP-PTL 275 G S P E L D PPPPP P PT+ Sbjct: 525 SIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 566 Score = 32.7 bits (73), Expect = 0.53 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 2/54 (3%) Query: 240 TPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDG--PPAVSS 291 T GP L FP+ PG P LG PP +L+ P P G PP +S+ Sbjct: 906 TAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSA 959 Score = 31.6 bits (70), Expect = 1.2 Identities = 47/190 (24%), Positives = 71/190 (37%), Gaps = 14/190 (7%) Query: 75 PHESRTNTDILETLKRRGIGLDGPELEPDEG-PEEPGEK---FRRLAGEGGDPALPRPRL 130 PH + L L+R + L GP+L P+ P+ + R+A DP L R ++ Sbjct: 807 PHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP-LARLQM 865 Query: 131 YPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAG----PPG-LVHP 185 + P ++ L DP G A P P A P PPG L +P Sbjct: 866 FNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPL-TAGPHLARFPYPPGTLPNP 924 Query: 186 LF-SPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPP 244 L P H P++ R DLPG + P + +++++ A Sbjct: 925 LLGQPPHEHEMLRHPVFGTPYPR--DLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQW 982 Query: 245 LGSFPFLPGG 254 L P + GG Sbjct: 983 LHGHPHMHGG 992 Score = 30.4 bits (67), Expect = 2.6 Identities = 39/164 (23%), Positives = 56/164 (34%), Gaps = 11/164 (6%) Query: 203 PTEGR------RSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPP 256 P+EG RS G + P+ +RS + +P + L PP Sbjct: 126 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 185 Query: 257 EYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPV 316 P PP P P+ G P A + P G + + + + P P Sbjct: 186 ALQAPTGVTPAPSSAPPG-TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 244 Query: 317 SI-KSERLSP-APGGPGDFPKTFPYPLL--LARSLAEPLRPGPA 356 I ++ L P P P P P+P L L S +P P A Sbjct: 245 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 288 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 69.3 bits (168), Expect = 5e-12 Identities = 75/224 (33%), Positives = 85/224 (37%), Gaps = 36/224 (16%) Query: 126 PRPRLYPAAPAM-----PSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 PR + P AP P P LP P P S PSPF A PP Sbjct: 913 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP-----PHLSGPSPFSMNANLPPPP 967 Query: 181 GLVHPLFSPS--HLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSL----YSGLQN 234 L PL S S H S PPPL L + + LP A P G L S++L S Sbjct: 968 AL-KPLSSLSTHHPPSAHPPPLQLMPQSQ--PLPSSPAQPPG-LTQSQNLPPPPASHPPT 1023 Query: 235 PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294 P PP PF+PGGPP PP P PP P PP + S Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPA----GPGTSAQPPCSGAAAS 1076 Query: 295 GGRSLGEEGPPTRGASPPTPPVSIKSERLSPA--PGGPGDFPKT 336 GG G G+S P P V IK E L A P P P++ Sbjct: 1077 GGSIAG-------GSSCPLPTVQIKEEALDDAEEPESPPPPPRS 1113 Score = 44.3 bits (103), Expect = 2e-04 Identities = 68/257 (26%), Positives = 89/257 (34%), Gaps = 28/257 (10%) Query: 123 PAL-PRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPG 181 PAL P+ P P PSP L PS A P P P + +AGP Sbjct: 804 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL- 862 Query: 182 LVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGG----LAGPRGGLN--TSRSLYSGLQNP 235 L HP P P LP + + P G A P L S+S Q P Sbjct: 863 LQHP---------GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913 Query: 236 CSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQP--SRGDGPPAVSSQP 293 P PL P PP + P P PP L+ P + PP + +P Sbjct: 914 REQPLPPAPLAMPHIKP--PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 971 Query: 294 SGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTF---PYPLLLARSLAEP 350 SL PP+ A PP + +S+ L +P P ++ P P + Sbjct: 972 LS--SLSTHHPPS--AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027 Query: 351 LRPGPALRRLPLADGWP 367 + P P + P G P Sbjct: 1028 VAPQPPFAQHPFVPGGP 1044 Score = 43.1 bits (100), Expect = 4e-04 Identities = 71/254 (27%), Positives = 89/254 (35%), Gaps = 52/254 (20%) Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 G P LP P P+A A+P P G A A ++P P AP Sbjct: 757 GTPQLPTPGPTPSATAVP---------------PQGSPTASQAPNQPQ--APTAPVPHTH 799 Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240 P P S PPP P L G P + L+ Q P Sbjct: 800 IQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHG--QGP----- 851 Query: 241 PGP-PLGSFPFL--PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGP----PAVSSQ- 292 PGP L + P L PG P +GL PP + Q G P P S Q Sbjct: 852 PGPHSLQAGPLLQHPGPPQPFGL-----------PPQASQGQAPLGTSPAAAYPHTSLQL 900 Query: 293 PSGGRSLGEEGPPTRGASPPTPPV--SIKSERLSPAPGGPGDFPKTFPYPLLLAR----S 346 P+ +L + PP PP P IK +P P P P+ +P L+ S Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA--PQAHKHPPHLSGPSPFS 958 Query: 347 LAEPLRPGPALRRL 360 + L P PAL+ L Sbjct: 959 MNANLPPPPALKPL 972 Score = 35.4 bits (80), Expect = 0.082 Identities = 50/162 (30%), Positives = 61/162 (37%), Gaps = 43/162 (26%) Query: 125 LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVH 184 +P+ + P++PA P LPPP PA P+ AP+ PP H Sbjct: 991 MPQSQPLPSSPAQPPGLTQSQNLPPP-----------PASHPPTGLHQVAPQ--PPFAQH 1037 Query: 185 PLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCS--TATPG 242 P F P PPP+ PT S P AGP + Q PCS A+ G Sbjct: 1038 P-FVPG-----GPPPITPPTCPSTSTPP---AGPG----------TSAQPPCSGAAASGG 1078 Query: 243 PPLG--SFPFLPGGPPEYGLGD------PPPPPGLLQP-PTL 275 G S P E L D PPPPP P PT+ Sbjct: 1079 SIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 1120 Score = 32.7 bits (73), Expect = 0.53 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 2/54 (3%) Query: 240 TPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDG--PPAVSS 291 T GP L FP+ PG P LG PP +L+ P P G PP +S+ Sbjct: 1460 TAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSA 1513 Score = 31.6 bits (70), Expect = 1.2 Identities = 47/190 (24%), Positives = 71/190 (37%), Gaps = 14/190 (7%) Query: 75 PHESRTNTDILETLKRRGIGLDGPELEPDEG-PEEPGEK---FRRLAGEGGDPALPRPRL 130 PH + L L+R + L GP+L P+ P+ + R+A DP L R ++ Sbjct: 1361 PHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP-LARLQM 1419 Query: 131 YPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAG----PPG-LVHP 185 + P ++ L DP G A P P A P PPG L +P Sbjct: 1420 FNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPL-TAGPHLARFPYPPGTLPNP 1478 Query: 186 LF-SPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPP 244 L P H P++ R DLPG + P + +++++ A Sbjct: 1479 LLGQPPHEHEMLRHPVFGTPYPR--DLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQW 1536 Query: 245 LGSFPFLPGG 254 L P + GG Sbjct: 1537 LHGHPHMHGG 1546 Score = 30.4 bits (67), Expect = 2.6 Identities = 39/164 (23%), Positives = 56/164 (34%), Gaps = 11/164 (6%) Query: 203 PTEGR------RSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPP 256 P+EG RS G + P+ +RS + +P + L PP Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739 Query: 257 EYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPV 316 P PP P P+ G P A + P G + + + + P P Sbjct: 740 ALQAPTGVTPAPSSAPPG-TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 798 Query: 317 SI-KSERLSP-APGGPGDFPKTFPYPLL--LARSLAEPLRPGPA 356 I ++ L P P P P P+P L L S +P P A Sbjct: 799 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 842 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 69.3 bits (168), Expect = 5e-12 Identities = 75/224 (33%), Positives = 85/224 (37%), Gaps = 36/224 (16%) Query: 126 PRPRLYPAAPAM-----PSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 PR + P AP P P LP P P S PSPF A PP Sbjct: 913 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP-----PHLSGPSPFSMNANLPPPP 967 Query: 181 GLVHPLFSPS--HLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSL----YSGLQN 234 L PL S S H S PPPL L + + LP A P G L S++L S Sbjct: 968 AL-KPLSSLSTHHPPSAHPPPLQLMPQSQ--PLPSSPAQPPG-LTQSQNLPPPPASHPPT 1023 Query: 235 PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294 P PP PF+PGGPP PP P PP P PP + S Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPA----GPGTSAQPPCSGAAAS 1076 Query: 295 GGRSLGEEGPPTRGASPPTPPVSIKSERLSPA--PGGPGDFPKT 336 GG G G+S P P V IK E L A P P P++ Sbjct: 1077 GGSIAG-------GSSCPLPTVQIKEEALDDAEEPESPPPPPRS 1113 Score = 44.3 bits (103), Expect = 2e-04 Identities = 68/257 (26%), Positives = 89/257 (34%), Gaps = 28/257 (10%) Query: 123 PAL-PRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPG 181 PAL P+ P P PSP L PS A P P P + +AGP Sbjct: 804 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL- 862 Query: 182 LVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGG----LAGPRGGLN--TSRSLYSGLQNP 235 L HP P P LP + + P G A P L S+S Q P Sbjct: 863 LQHP---------GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913 Query: 236 CSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQP--SRGDGPPAVSSQP 293 P PL P PP + P P PP L+ P + PP + +P Sbjct: 914 REQPLPPAPLAMPHIKP--PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 971 Query: 294 SGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTF---PYPLLLARSLAEP 350 SL PP+ A PP + +S+ L +P P ++ P P + Sbjct: 972 LS--SLSTHHPPS--AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027 Query: 351 LRPGPALRRLPLADGWP 367 + P P + P G P Sbjct: 1028 VAPQPPFAQHPFVPGGP 1044 Score = 43.1 bits (100), Expect = 4e-04 Identities = 71/254 (27%), Positives = 89/254 (35%), Gaps = 52/254 (20%) Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 G P LP P P+A A+P P G A A ++P P AP Sbjct: 757 GTPQLPTPGPTPSATAVP---------------PQGSPTASQAPNQPQ--APTAPVPHTH 799 Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240 P P S PPP P L G P + L+ Q P Sbjct: 800 IQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHG--QGP----- 851 Query: 241 PGP-PLGSFPFL--PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGP----PAVSSQ- 292 PGP L + P L PG P +GL PP + Q G P P S Q Sbjct: 852 PGPHSLQAGPLLQHPGPPQPFGL-----------PPQASQGQAPLGTSPAAAYPHTSLQL 900 Query: 293 PSGGRSLGEEGPPTRGASPPTPPV--SIKSERLSPAPGGPGDFPKTFPYPLLLAR----S 346 P+ +L + PP PP P IK +P P P P+ +P L+ S Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA--PQAHKHPPHLSGPSPFS 958 Query: 347 LAEPLRPGPALRRL 360 + L P PAL+ L Sbjct: 959 MNANLPPPPALKPL 972 Score = 35.4 bits (80), Expect = 0.082 Identities = 50/162 (30%), Positives = 61/162 (37%), Gaps = 43/162 (26%) Query: 125 LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVH 184 +P+ + P++PA P LPPP PA P+ AP+ PP H Sbjct: 991 MPQSQPLPSSPAQPPGLTQSQNLPPP-----------PASHPPTGLHQVAPQ--PPFAQH 1037 Query: 185 PLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCS--TATPG 242 P F P PPP+ PT S P AGP + Q PCS A+ G Sbjct: 1038 P-FVPG-----GPPPITPPTCPSTSTPP---AGPG----------TSAQPPCSGAAASGG 1078 Query: 243 PPLG--SFPFLPGGPPEYGLGD------PPPPPGLLQP-PTL 275 G S P E L D PPPPP P PT+ Sbjct: 1079 SIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 1120 Score = 32.7 bits (73), Expect = 0.53 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 2/54 (3%) Query: 240 TPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDG--PPAVSS 291 T GP L FP+ PG P LG PP +L+ P P G PP +S+ Sbjct: 1460 TAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSA 1513 Score = 31.6 bits (70), Expect = 1.2 Identities = 47/190 (24%), Positives = 71/190 (37%), Gaps = 14/190 (7%) Query: 75 PHESRTNTDILETLKRRGIGLDGPELEPDEG-PEEPGEK---FRRLAGEGGDPALPRPRL 130 PH + L L+R + L GP+L P+ P+ + R+A DP L R ++ Sbjct: 1361 PHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP-LARLQM 1419 Query: 131 YPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAG----PPG-LVHP 185 + P ++ L DP G A P P A P PPG L +P Sbjct: 1420 FNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPL-TAGPHLARFPYPPGTLPNP 1478 Query: 186 LF-SPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPP 244 L P H P++ R DLPG + P + +++++ A Sbjct: 1479 LLGQPPHEHEMLRHPVFGTPYPR--DLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQW 1536 Query: 245 LGSFPFLPGG 254 L P + GG Sbjct: 1537 LHGHPHMHGG 1546 Score = 30.4 bits (67), Expect = 2.6 Identities = 39/164 (23%), Positives = 56/164 (34%), Gaps = 11/164 (6%) Query: 203 PTEGR------RSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPP 256 P+EG RS G + P+ +RS + +P + L PP Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739 Query: 257 EYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPV 316 P PP P P+ G P A + P G + + + + P P Sbjct: 740 ALQAPTGVTPAPSSAPPG-TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 798 Query: 317 SI-KSERLSP-APGGPGDFPKTFPYPLL--LARSLAEPLRPGPA 356 I ++ L P P P P P+P L L S +P P A Sbjct: 799 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 842 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 68.6 bits (166), Expect = 9e-12 Identities = 85/269 (31%), Positives = 102/269 (37%), Gaps = 61/269 (22%) Query: 94 GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALP----------RPRLYPAAPAMPSPD 141 GL GP+ EP P PG K G GDP LP +P L P P P P Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIK-----GSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPP 1130 Query: 142 VVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAP-------KAGPPGLVHPLFSPSHLTS 194 G PPG +P GE P P +P P + G PG P Sbjct: 1131 GPKGISGPPG-NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 195 KTPPPLYLP-TEGRRSD--LPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLG 246 P P LP G++ D LPG GL GP+G + G+Q P PGPP Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG--EPGFHGFPGVQGP-----PGPPGS 1242 Query: 247 SFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPT 306 P L G G PP PGL P +GPP + P G GE+G P Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGLPGP-----------EGPPGL---PGNGGIKGEKGNPG 1288 Query: 307 RGASPPTPPVSIKSERLSPA----PGGPG 331 + P P +K ++ P PG PG Sbjct: 1289 QPGLPGLP--GLKGDQGPPGLQGNPGRPG 1315 Score = 64.7 bits (156), Expect = 1e-10 Identities = 89/310 (28%), Positives = 106/310 (34%), Gaps = 53/310 (17%) Query: 94 GLDGPELEPDEGPEEPGEK-FRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGC 152 G+ GP+ +P + +PG+ G GD LP P P +P + G+ PG Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG---IPGSKGEPGI 703 Query: 153 DPSGL-GEALPAQSRPSPFRPAAPKA-GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSD 210 GL G P P P AP G GL P P K P LP Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 211 LPG--GLAGPRGGLN-------TSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLG 261 LPG G GP+G R+ GL P P G P P G P G+ Sbjct: 764 LPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG--PMGPPGLPGIGVQ 821 Query: 262 DPPPPPGLLQP---PTLAPWQPSRGD---------GPPAVSSQPSGGRSLGEEGPP---- 305 PP PPG+ P P L +GD GPP P + G GPP Sbjct: 822 GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881 Query: 306 ------------TRG----ASPPTPPVSIKSERLSPAPGGPGD----FPKTFPYPLLLAR 345 T+G PP PP + S PG GD P P Sbjct: 882 LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941 Query: 346 SLAEPLRPGP 355 S EP PGP Sbjct: 942 SKGEPGLPGP 951 Score = 58.5 bits (140), Expect = 9e-09 Identities = 70/245 (28%), Positives = 89/245 (36%), Gaps = 57/245 (23%) Query: 106 PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQS 165 P +PG+ L+G+ G P P P+ P P P G + PPG L + Sbjct: 987 PGDPGQP--GLSGQPGLPGPPGPKGNPGLPGQP------GLIGPPG-----LKGTIGDMG 1033 Query: 166 RPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPG-------GLAGP 218 P P GPPG PS + + P +G + D PG GL GP Sbjct: 1034 FPGP----QGVEGPPG-------PSGVPGQPGSPGLPGQKGDKGD-PGISSIGLPGLPGP 1081 Query: 219 RG-----GLNTSRSLYSGLQNPCSTATPGPP-------LGSFPFLPGGPPEYGLGDPPPP 266 +G G + + + +P PG P L FP PG P G+ PP Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141 Query: 267 PGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326 PGL P P G G P P GE+G P + P P K E P Sbjct: 1142 PGLPGEP-----GPVGGGGHPGQPGPP------GEKGKPGQDGIP--GPAGQKGEPGQPG 1188 Query: 327 PGGPG 331 G PG Sbjct: 1189 FGNPG 1193 Score = 58.2 bits (139), Expect = 1e-08 Identities = 78/276 (28%), Positives = 94/276 (34%), Gaps = 47/276 (17%) Query: 92 GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAA------------PAMPS 139 G+ D EL P PG G+ G P LP P+ P P +P Sbjct: 555 GMKGDKGELGSPGAPGLPG--LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612 Query: 140 PDVVYGALPPPGCDPSG-LGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP 198 G + PPG P G +GE + A G PG+ P P ++ Sbjct: 613 LPGNIGPMGPPGFGPPGPVGE--------KGIQGVAGNPGQPGIPGPKGDPGQTITQPGK 664 Query: 199 PLYLPTEGRRSD--LPG--GLAGPRG--GLNTSRSLYSGLQNPCSTATPGPP-------L 245 P GR D LPG GL G G G+ S+ G PGPP + Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK----GEPGIPGIGLPGPPGPKGFPGI 720 Query: 246 GSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAV-----SSQPSGGRSL- 299 P PG P GL PP PPG P + GPP + + P G R Sbjct: 721 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 780 Query: 300 GEEGPPTRGASPPTP-PVSIKSERLSPAPGGPGDFP 334 G GPP R P P P P GP P Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816 Score = 57.4 bits (137), Expect = 2e-08 Identities = 84/265 (31%), Positives = 92/265 (34%), Gaps = 75/265 (28%) Query: 94 GLDGPELEP-------DEG-PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145 G GPE P D+G P PG K G G P LP P P MP D G Sbjct: 63 GFPGPEGPPGPRGQKGDDGIPGPPGPK-----GIRGPPGLPGFPGTPGLPGMPGHDGAPG 117 Query: 146 ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSP-SHLTSKTPPPLYLP 203 PGC+ + P SP P GPPG+ P S + S P P P Sbjct: 118 PQGIPGCNGTKGERGFPG----SPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP 173 Query: 204 TEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDP 263 G GP G GL P T PG P+G P GPP GL P Sbjct: 174 ----------GYPGPPG--------IQGLPGP--TGIPG-PIG-----PPGPP--GLMGP 205 Query: 264 PPPPGL----------------------LQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGE 301 P PPGL LQ P P Q S P V Q G+ Sbjct: 206 PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD 265 Query: 302 EGPP----TRGASPPTPPVSIKSER 322 GPP RG PP PP K E+ Sbjct: 266 RGPPGPPGIRG--PPGPPGGEKGEK 288 Score = 55.5 bits (132), Expect = 8e-08 Identities = 70/220 (31%), Positives = 78/220 (35%), Gaps = 67/220 (30%) Query: 94 GLDG-PELEPDEGPE----EPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALP 148 GL G P L+ D+GP PG L G GDP LP P P M P V G+ Sbjct: 1291 GLPGLPGLKGDQGPPGLQGNPGRP--GLNGMKGDPGLPG---VPGFPGMKGPSGVPGSAG 1345 Query: 149 PPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRR 208 P G +P +G GPPGL P + PP G + Sbjct: 1346 PEG-EPGLIGPP-----------------GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK 1387 Query: 209 SDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPP----LGSF---------PFLPGGP 255 GL GP+G GL P T PG P L F P LPG P Sbjct: 1388 -----GLPGPQGP--------QGLPGP--TGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP 1432 Query: 256 PEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSG 295 GL PP P GL PP GPP SS G Sbjct: 1433 GTRGLDGPPGPDGLQGPP-----------GPPGTSSVAHG 1461 Score = 52.0 bits (123), Expect = 8e-07 Identities = 85/290 (29%), Positives = 102/290 (35%), Gaps = 66/290 (22%) Query: 94 GLDG-PELEPDEGPE-------EPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145 GLDG P + D GP PG + G G P +P P P +P G Sbjct: 790 GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEK---G 846 Query: 146 ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSPSHLTSKTPPPLYLPT 204 PPG D G P R SP P AP GPPG SP L K + T Sbjct: 847 DPGPPGLDVPG-----PPGERGSPGIPGAPGPIGPPG------SPG-LPGKAGASGFPGT 894 Query: 205 EGRRSDL-PGGLAGPRG--------GLNTSRSLYS--GLQNPCST-------ATPGPPLG 246 +G + P G GP G GL L GL P PGPP Sbjct: 895 KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954 Query: 247 ---------------SFPFLPG--GPPEY-GLGDPPPPPGLLQPPTLAPWQPSRGD---- 284 P +PG GP Y GL P PGL P L +G+ Sbjct: 955 MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014 Query: 285 GPPAVSSQPSGGRSLGEEG-PPTRGASPPTPPVSIKSERLSPA-PGGPGD 332 G P + P ++G+ G P +G P P + + SP PG GD Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064 Score = 51.2 bits (121), Expect = 1e-06 Identities = 89/338 (26%), Positives = 109/338 (32%), Gaps = 96/338 (28%) Query: 94 GLDGPELEPD-EGPE-EPGEKFRR-LAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPP 150 GL GP P G + EPG L G G+P P P P +P P + G + PP Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP---PGIQGLPGPTGIPGPIGPP 197 Query: 151 GCDPSGLGEALPAQSRPSP-------FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLP 203 G P GL P P F+ + G GL P P ++ + P + Sbjct: 198 G--PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP---ID 252 Query: 204 TEGRRSD--LPG--------GLAGPRG------------------------GLNTSRSLY 229 E ++ D LPG G+ GP G G N + Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 230 SGLQNPC---------------STATPGPP------------LGS-----FPFLPGGPPE 257 +P T PGPP +G P LPG E Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 258 YGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVS 317 G PPGL PP A GPP P G+EGPP G S P PP Sbjct: 373 RGFPGIQGPPGLPGPPGAAVM------GPPGPPGFPGERGQKGDEGPP--GISIPGPPGL 424 Query: 318 IKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGP 355 PG PG P + + EP PGP Sbjct: 425 DGQPGAPGLPGPPGPAGPHIP----PSDEICEPGPPGP 458 Score = 47.8 bits (112), Expect = 2e-05 Identities = 91/323 (28%), Positives = 110/323 (34%), Gaps = 73/323 (22%) Query: 94 GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151 G G + EP + P + GE G+ G P LP YP P G PPG Sbjct: 286 GEKGEQGEPGKRGKPGKDGEN-----GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340 Query: 152 CDPSGL-----GEALPAQSRPSPFRPAAPKA----------GPPGLVHPLFSPSHLTSKT 196 P GL G + + + P P GPPGL P P Sbjct: 341 --PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP---PGAAVMGP 395 Query: 197 PPPLYLPTE-GRRSDL--PG-GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLP 252 P P P E G++ D PG + GP G G P + PGPP + P +P Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPG--------LDG--QPGAPGLPGPPGPAGPHIP 445 Query: 253 GGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD-----------------GPPAVSSQPSG 295 E PP PPG L Q +GD G P + P Sbjct: 446 PS-DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGP 504 Query: 296 GRSLGEEGPP-TRGASPPTPPVSIKSERLSPAPGGPGDFP---------KTFPYPLLLAR 345 SLG G +G + T P + + APG PG FP TFP Sbjct: 505 PGSLGFPGQKGEKGQAGATGPKGLPG--IPGAPGAPG-FPGSKGEPGDILTFPGMKGDKG 561 Query: 346 SLAEPLRPG-PALRRLPLADGWP 367 L P PG P L P DG P Sbjct: 562 ELGSPGAPGLPGLPGTPGQDGLP 584 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 67.8 bits (164), Expect = 1e-11 Identities = 74/231 (32%), Positives = 91/231 (39%), Gaps = 20/231 (8%) Query: 126 PRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPA---APKAGPPGL 182 PRP PA P P LP P P+G + +PAQ S PA AP+ GP Sbjct: 897 PRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQ 956 Query: 183 VHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPG 242 HP PS PP LP + P GL +S Y P P Sbjct: 957 PHPQPHPSQAFGPQPPQQPLPLQH-----PHLFPPQAPGLLPPQSPYPYAPQPGVLGQPP 1011 Query: 243 PPLGS--FPFLPGGP-PEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRS- 298 PPL + +P P P + P P PG QPP P G PA S++P G ++ Sbjct: 1012 PPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPP-----HPPLAYG-PAPSTRPMGPQAA 1065 Query: 299 -LGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLA 348 L GP + G S P+P + + S SP PG P P L R A Sbjct: 1066 PLTIRGPSSAGQSTPSPHL-VPSPAPSPGPGPVPPRPPAAEPPPCLRRGAA 1115 Score = 52.0 bits (123), Expect = 8e-07 Identities = 75/267 (28%), Positives = 86/267 (32%), Gaps = 56/267 (20%) Query: 115 RLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPS---GLGEALPAQSRPSPFR 171 R G P P P LYPA P +V + P G S G+G Sbjct: 806 RAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVG------------- 852 Query: 172 PAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSG 231 PA P AG P P FS L P + ++ +P A Sbjct: 853 PAPPVAGLPSAPPPQFSGPELAMAVRPAT-TTVDSIQAPIPSHTA--------------- 896 Query: 232 LQNPCSTATPGPPLGSFPFLPGGPPEYGLGDP-PPPPGLLQPPTLAPWQPSRGDGPPAVS 290 P TP PP FP PP L P P G QP P Q G PA Sbjct: 897 ---PRPNPTPAPPPPCFPV----PPPQPLPTPYTYPAGAKQP---IPAQHHFSSGIPAGF 946 Query: 291 SQPSGGRSLGEEGPP----TRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARS 346 P G P G PP P+ ++ L P P PG P PYP Sbjct: 947 PAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFP-PQAPGLLPPQSPYPYAPQPG 1005 Query: 347 -LAEP-------LRPGPALRRLPLADG 365 L +P L PGPA LP G Sbjct: 1006 VLGQPPPPLHTQLYPGPAQDPLPAHSG 1032 Score = 31.6 bits (70), Expect = 1.2 Identities = 32/118 (27%), Positives = 41/118 (34%), Gaps = 33/118 (27%) Query: 124 ALPRPRLYPAAPAMPSPDVVYGALP---PPGCD--------PSGLGEALPA--------- 163 ALP P P P P P + YG P P G PS G++ P+ Sbjct: 1033 ALPFPS--PGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAP 1090 Query: 164 QSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGG 221 P P P P A PP + + + L S +P + GG P GG Sbjct: 1091 SPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQH-----------GGTQSPGGG 1137 Score = 31.6 bits (70), Expect = 1.2 Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 6/59 (10%) Query: 124 ALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPS--PFRPAAPKAGPP 180 +LP P P P P+ + P P P L LP +P P P AP +GPP Sbjct: 1519 SLPGPAEPPGLPPASLPE----STPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPP 1573 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 66.6 bits (161), Expect = 3e-11 Identities = 86/269 (31%), Positives = 103/269 (38%), Gaps = 55/269 (20%) Query: 94 GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALP----------RPRLYPAAPAMPSPD 141 GL GP+ EP P PG K G GDP LP +P L P P P P Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIK-----GSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPP 1130 Query: 142 VVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAP-------KAGPPGLVHPLFSPSHLTS 194 G PPG +P GE P P +P P + G PG P Sbjct: 1131 GPKGISGPPG-NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 195 KTPPPLYLP-TEGRRSD--LPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLG 246 P P LP G++ D LPG GL GP+G + G+Q P PGPP Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG--EPGFHGFPGVQGP-----PGPPGS 1242 Query: 247 SFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPT 306 P L G G PP PG PT P +GPP + P G GE+G P Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPG----PTGFQGLPG-PEGPPGL---PGNGGIKGEKGNPG 1294 Query: 307 RGASPPTPPVSIKSERLSPA----PGGPG 331 + P P +K ++ P PG PG Sbjct: 1295 QPGLPGLP--GLKGDQGPPGLQGNPGRPG 1321 Score = 64.7 bits (156), Expect = 1e-10 Identities = 89/310 (28%), Positives = 106/310 (34%), Gaps = 53/310 (17%) Query: 94 GLDGPELEPDEGPEEPGEK-FRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGC 152 G+ GP+ +P + +PG+ G GD LP P P +P + G+ PG Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG---IPGSKGEPGI 703 Query: 153 DPSGL-GEALPAQSRPSPFRPAAPKA-GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSD 210 GL G P P P AP G GL P P K P LP Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 211 LPG--GLAGPRGGLN-------TSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLG 261 LPG G GP+G R+ GL P P G P P G P G+ Sbjct: 764 LPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG--PMGPPGLPGIGVQ 821 Query: 262 DPPPPPGLLQP---PTLAPWQPSRGD---------GPPAVSSQPSGGRSLGEEGPP---- 305 PP PPG+ P P L +GD GPP P + G GPP Sbjct: 822 GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881 Query: 306 ------------TRG----ASPPTPPVSIKSERLSPAPGGPGD----FPKTFPYPLLLAR 345 T+G PP PP + S PG GD P P Sbjct: 882 LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941 Query: 346 SLAEPLRPGP 355 S EP PGP Sbjct: 942 SKGEPGLPGP 951 Score = 58.5 bits (140), Expect = 9e-09 Identities = 70/245 (28%), Positives = 89/245 (36%), Gaps = 57/245 (23%) Query: 106 PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQS 165 P +PG+ L+G+ G P P P+ P P P G + PPG L + Sbjct: 987 PGDPGQP--GLSGQPGLPGPPGPKGNPGLPGQP------GLIGPPG-----LKGTIGDMG 1033 Query: 166 RPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPG-------GLAGP 218 P P GPPG PS + + P +G + D PG GL GP Sbjct: 1034 FPGP----QGVEGPPG-------PSGVPGQPGSPGLPGQKGDKGD-PGISSIGLPGLPGP 1081 Query: 219 RG-----GLNTSRSLYSGLQNPCSTATPGPP-------LGSFPFLPGGPPEYGLGDPPPP 266 +G G + + + +P PG P L FP PG P G+ PP Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141 Query: 267 PGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326 PGL P P G G P P GE+G P + P P K E P Sbjct: 1142 PGLPGEP-----GPVGGGGHPGQPGPP------GEKGKPGQDGIP--GPAGQKGEPGQPG 1188 Query: 327 PGGPG 331 G PG Sbjct: 1189 FGNPG 1193 Score = 58.2 bits (139), Expect = 1e-08 Identities = 78/276 (28%), Positives = 94/276 (34%), Gaps = 47/276 (17%) Query: 92 GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAA------------PAMPS 139 G+ D EL P PG G+ G P LP P+ P P +P Sbjct: 555 GMKGDKGELGSPGAPGLPG--LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612 Query: 140 PDVVYGALPPPGCDPSG-LGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP 198 G + PPG P G +GE + A G PG+ P P ++ Sbjct: 613 LPGNIGPMGPPGFGPPGPVGE--------KGIQGVAGNPGQPGIPGPKGDPGQTITQPGK 664 Query: 199 PLYLPTEGRRSD--LPG--GLAGPRG--GLNTSRSLYSGLQNPCSTATPGPP-------L 245 P GR D LPG GL G G G+ S+ G PGPP + Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK----GEPGIPGIGLPGPPGPKGFPGI 720 Query: 246 GSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAV-----SSQPSGGRSL- 299 P PG P GL PP PPG P + GPP + + P G R Sbjct: 721 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 780 Query: 300 GEEGPPTRGASPPTP-PVSIKSERLSPAPGGPGDFP 334 G GPP R P P P P GP P Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816 Score = 57.4 bits (137), Expect = 2e-08 Identities = 84/265 (31%), Positives = 92/265 (34%), Gaps = 75/265 (28%) Query: 94 GLDGPELEP-------DEG-PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145 G GPE P D+G P PG K G G P LP P P MP D G Sbjct: 63 GFPGPEGPPGPRGQKGDDGIPGPPGPK-----GIRGPPGLPGFPGTPGLPGMPGHDGAPG 117 Query: 146 ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSP-SHLTSKTPPPLYLP 203 PGC+ + P SP P GPPG+ P S + S P P P Sbjct: 118 PQGIPGCNGTKGERGFPG----SPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP 173 Query: 204 TEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDP 263 G GP G GL P T PG P+G P GPP GL P Sbjct: 174 ----------GYPGPPG--------IQGLPGP--TGIPG-PIG-----PPGPP--GLMGP 205 Query: 264 PPPPGL----------------------LQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGE 301 P PPGL LQ P P Q S P V Q G+ Sbjct: 206 PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD 265 Query: 302 EGPP----TRGASPPTPPVSIKSER 322 GPP RG PP PP K E+ Sbjct: 266 RGPPGPPGIRG--PPGPPGGEKGEK 288 Score = 57.4 bits (137), Expect = 2e-08 Identities = 72/248 (29%), Positives = 88/248 (35%), Gaps = 68/248 (27%) Query: 92 GIGLDGPELEPDEGPEEPGEK-----FRRLAGEGGDPALPR------PRLYPAAPAMPSP 140 G L+GP+ P GP+ P + F+ L G G P LP + P P +P Sbjct: 1244 GPALEGPKGNP--GPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1301 Query: 141 DVVYGALPPPGC--------------DPSGLG-EALPAQSRPSPFRPAAPKAGPPGLVHP 185 + G PPG DP G P PS +A G PGL+ P Sbjct: 1302 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1361 Query: 186 LFSPSHLTSKTPPPLYLPTEGRRSDLPG-----GLAGPRGGLNTSRSLYSGLQNPCSTAT 240 P L + + + + +PG GL GP+G GL P T Sbjct: 1362 P-GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP--------QGLPGP--TGP 1410 Query: 241 PGPP----LGSF---------PFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPP 287 PG P L F P LPG P GL PP P GL PP GPP Sbjct: 1411 PGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP-----------GPP 1459 Query: 288 AVSSQPSG 295 SS G Sbjct: 1460 GTSSVAHG 1467 Score = 52.0 bits (123), Expect = 8e-07 Identities = 85/290 (29%), Positives = 102/290 (35%), Gaps = 66/290 (22%) Query: 94 GLDG-PELEPDEGPE-------EPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145 GLDG P + D GP PG + G G P +P P P +P G Sbjct: 790 GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEK---G 846 Query: 146 ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSPSHLTSKTPPPLYLPT 204 PPG D G P R SP P AP GPPG SP L K + T Sbjct: 847 DPGPPGLDVPG-----PPGERGSPGIPGAPGPIGPPG------SPG-LPGKAGASGFPGT 894 Query: 205 EGRRSDL-PGGLAGPRG--------GLNTSRSLYS--GLQNPCST-------ATPGPPLG 246 +G + P G GP G GL L GL P PGPP Sbjct: 895 KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954 Query: 247 ---------------SFPFLPG--GPPEY-GLGDPPPPPGLLQPPTLAPWQPSRGD---- 284 P +PG GP Y GL P PGL P L +G+ Sbjct: 955 MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014 Query: 285 GPPAVSSQPSGGRSLGEEG-PPTRGASPPTPPVSIKSERLSPA-PGGPGD 332 G P + P ++G+ G P +G P P + + SP PG GD Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064 Score = 51.2 bits (121), Expect = 1e-06 Identities = 89/338 (26%), Positives = 109/338 (32%), Gaps = 96/338 (28%) Query: 94 GLDGPELEPD-EGPE-EPGEKFRR-LAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPP 150 GL GP P G + EPG L G G+P P P P +P P + G + PP Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP---PGIQGLPGPTGIPGPIGPP 197 Query: 151 GCDPSGLGEALPAQSRPSP-------FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLP 203 G P GL P P F+ + G GL P P ++ + P + Sbjct: 198 G--PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP---ID 252 Query: 204 TEGRRSD--LPG--------GLAGPRG------------------------GLNTSRSLY 229 E ++ D LPG G+ GP G G N + Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 230 SGLQNPC---------------STATPGPP------------LGS-----FPFLPGGPPE 257 +P T PGPP +G P LPG E Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 258 YGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVS 317 G PPGL PP A GPP P G+EGPP G S P PP Sbjct: 373 RGFPGIQGPPGLPGPPGAAVM------GPPGPPGFPGERGQKGDEGPP--GISIPGPPGL 424 Query: 318 IKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGP 355 PG PG P + + EP PGP Sbjct: 425 DGQPGAPGLPGPPGPAGPHIP----PSDEICEPGPPGP 458 Score = 47.8 bits (112), Expect = 2e-05 Identities = 91/323 (28%), Positives = 110/323 (34%), Gaps = 73/323 (22%) Query: 94 GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151 G G + EP + P + GE G+ G P LP YP P G PPG Sbjct: 286 GEKGEQGEPGKRGKPGKDGEN-----GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340 Query: 152 CDPSGL-----GEALPAQSRPSPFRPAAPKA----------GPPGLVHPLFSPSHLTSKT 196 P GL G + + + P P GPPGL P P Sbjct: 341 --PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP---PGAAVMGP 395 Query: 197 PPPLYLPTE-GRRSDL--PG-GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLP 252 P P P E G++ D PG + GP G G P + PGPP + P +P Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPG--------LDG--QPGAPGLPGPPGPAGPHIP 445 Query: 253 GGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD-----------------GPPAVSSQPSG 295 E PP PPG L Q +GD G P + P Sbjct: 446 PS-DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGP 504 Query: 296 GRSLGEEGPP-TRGASPPTPPVSIKSERLSPAPGGPGDFP---------KTFPYPLLLAR 345 SLG G +G + T P + + APG PG FP TFP Sbjct: 505 PGSLGFPGQKGEKGQAGATGPKGLPG--IPGAPGAPG-FPGSKGEPGDILTFPGMKGDKG 561 Query: 346 SLAEPLRPG-PALRRLPLADGWP 367 L P PG P L P DG P Sbjct: 562 ELGSPGAPGLPGLPGTPGQDGLP 584 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 65.9 bits (159), Expect = 6e-11 Identities = 84/269 (31%), Positives = 101/269 (37%), Gaps = 58/269 (21%) Query: 94 GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALP----------RPRLYPAAPAMPSPD 141 GL GP+ EP P PG K G GDP LP +P L P P P P Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIK-----GSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPP 1130 Query: 142 VVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAP-------KAGPPGLVHPLFSPSHLTS 194 G PPG +P GE P P +P P + G PG P Sbjct: 1131 GPKGISGPPG-NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 195 KTPPPLYLP-TEGRRSD--LPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLG 246 P P LP G++ D LPG GL GP+G + G+Q P PGPP Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG--EPGFHGFPGVQGP-----PGPPGS 1242 Query: 247 SFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPT 306 P L G G PP PG P +GPP + P G GE+G P Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGFQGLPG--------PEGPPGL---PGNGGIKGEKGNPG 1291 Query: 307 RGASPPTPPVSIKSERLSPA----PGGPG 331 + P P +K ++ P PG PG Sbjct: 1292 QPGLPGLP--GLKGDQGPPGLQGNPGRPG 1318 Score = 64.7 bits (156), Expect = 1e-10 Identities = 89/310 (28%), Positives = 106/310 (34%), Gaps = 53/310 (17%) Query: 94 GLDGPELEPDEGPEEPGEK-FRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGC 152 G+ GP+ +P + +PG+ G GD LP P P +P + G+ PG Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG---IPGSKGEPGI 703 Query: 153 DPSGL-GEALPAQSRPSPFRPAAPKA-GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSD 210 GL G P P P AP G GL P P K P LP Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 211 LPG--GLAGPRGGLN-------TSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLG 261 LPG G GP+G R+ GL P P G P P G P G+ Sbjct: 764 LPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG--PMGPPGLPGIGVQ 821 Query: 262 DPPPPPGLLQP---PTLAPWQPSRGD---------GPPAVSSQPSGGRSLGEEGPP---- 305 PP PPG+ P P L +GD GPP P + G GPP Sbjct: 822 GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881 Query: 306 ------------TRG----ASPPTPPVSIKSERLSPAPGGPGD----FPKTFPYPLLLAR 345 T+G PP PP + S PG GD P P Sbjct: 882 LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941 Query: 346 SLAEPLRPGP 355 S EP PGP Sbjct: 942 SKGEPGLPGP 951 Score = 58.5 bits (140), Expect = 9e-09 Identities = 70/245 (28%), Positives = 89/245 (36%), Gaps = 57/245 (23%) Query: 106 PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQS 165 P +PG+ L+G+ G P P P+ P P P G + PPG L + Sbjct: 987 PGDPGQP--GLSGQPGLPGPPGPKGNPGLPGQP------GLIGPPG-----LKGTIGDMG 1033 Query: 166 RPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPG-------GLAGP 218 P P GPPG PS + + P +G + D PG GL GP Sbjct: 1034 FPGP----QGVEGPPG-------PSGVPGQPGSPGLPGQKGDKGD-PGISSIGLPGLPGP 1081 Query: 219 RG-----GLNTSRSLYSGLQNPCSTATPGPP-------LGSFPFLPGGPPEYGLGDPPPP 266 +G G + + + +P PG P L FP PG P G+ PP Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141 Query: 267 PGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326 PGL P P G G P P GE+G P + P P K E P Sbjct: 1142 PGLPGEP-----GPVGGGGHPGQPGPP------GEKGKPGQDGIP--GPAGQKGEPGQPG 1188 Query: 327 PGGPG 331 G PG Sbjct: 1189 FGNPG 1193 Score = 58.5 bits (140), Expect = 9e-09 Identities = 72/245 (29%), Positives = 88/245 (35%), Gaps = 65/245 (26%) Query: 92 GIGLDGPELEPDEGPEEPGEK--FRRLAGEGGDPALPR------PRLYPAAPAMPSPDVV 143 G L+GP+ P GP+ P + F+ L G G P LP + P P +P + Sbjct: 1244 GPALEGPKGNP--GPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301 Query: 144 YGALPPPGC--------------DPSGLG-EALPAQSRPSPFRPAAPKAGPPGLVHPLFS 188 G PPG DP G P PS +A G PGL+ P Sbjct: 1302 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP-G 1360 Query: 189 PSHLTSKTPPPLYLPTEGRRSDLPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGP 243 P L + + + + +PG GL GP+G GL P T PG Sbjct: 1361 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP--------QGLPGP--TGPPGD 1410 Query: 244 P----LGSF---------PFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVS 290 P L F P LPG P GL PP P GL PP GPP S Sbjct: 1411 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP-----------GPPGTS 1459 Query: 291 SQPSG 295 S G Sbjct: 1460 SVAHG 1464 Score = 58.2 bits (139), Expect = 1e-08 Identities = 78/276 (28%), Positives = 94/276 (34%), Gaps = 47/276 (17%) Query: 92 GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAA------------PAMPS 139 G+ D EL P PG G+ G P LP P+ P P +P Sbjct: 555 GMKGDKGELGSPGAPGLPG--LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612 Query: 140 PDVVYGALPPPGCDPSG-LGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP 198 G + PPG P G +GE + A G PG+ P P ++ Sbjct: 613 LPGNIGPMGPPGFGPPGPVGE--------KGIQGVAGNPGQPGIPGPKGDPGQTITQPGK 664 Query: 199 PLYLPTEGRRSD--LPG--GLAGPRG--GLNTSRSLYSGLQNPCSTATPGPP-------L 245 P GR D LPG GL G G G+ S+ G PGPP + Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK----GEPGIPGIGLPGPPGPKGFPGI 720 Query: 246 GSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAV-----SSQPSGGRSL- 299 P PG P GL PP PPG P + GPP + + P G R Sbjct: 721 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 780 Query: 300 GEEGPPTRGASPPTP-PVSIKSERLSPAPGGPGDFP 334 G GPP R P P P P GP P Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816 Score = 57.4 bits (137), Expect = 2e-08 Identities = 84/265 (31%), Positives = 92/265 (34%), Gaps = 75/265 (28%) Query: 94 GLDGPELEP-------DEG-PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145 G GPE P D+G P PG K G G P LP P P MP D G Sbjct: 63 GFPGPEGPPGPRGQKGDDGIPGPPGPK-----GIRGPPGLPGFPGTPGLPGMPGHDGAPG 117 Query: 146 ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSP-SHLTSKTPPPLYLP 203 PGC+ + P SP P GPPG+ P S + S P P P Sbjct: 118 PQGIPGCNGTKGERGFPG----SPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP 173 Query: 204 TEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDP 263 G GP G GL P T PG P+G P GPP GL P Sbjct: 174 ----------GYPGPPG--------IQGLPGP--TGIPG-PIG-----PPGPP--GLMGP 205 Query: 264 PPPPGL----------------------LQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGE 301 P PPGL LQ P P Q S P V Q G+ Sbjct: 206 PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD 265 Query: 302 EGPP----TRGASPPTPPVSIKSER 322 GPP RG PP PP K E+ Sbjct: 266 RGPPGPPGIRG--PPGPPGGEKGEK 288 Score = 52.0 bits (123), Expect = 8e-07 Identities = 85/290 (29%), Positives = 102/290 (35%), Gaps = 66/290 (22%) Query: 94 GLDG-PELEPDEGPE-------EPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145 GLDG P + D GP PG + G G P +P P P +P G Sbjct: 790 GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEK---G 846 Query: 146 ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSPSHLTSKTPPPLYLPT 204 PPG D G P R SP P AP GPPG SP L K + T Sbjct: 847 DPGPPGLDVPG-----PPGERGSPGIPGAPGPIGPPG------SPG-LPGKAGASGFPGT 894 Query: 205 EGRRSDL-PGGLAGPRG--------GLNTSRSLYS--GLQNPCST-------ATPGPPLG 246 +G + P G GP G GL L GL P PGPP Sbjct: 895 KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954 Query: 247 ---------------SFPFLPG--GPPEY-GLGDPPPPPGLLQPPTLAPWQPSRGD---- 284 P +PG GP Y GL P PGL P L +G+ Sbjct: 955 MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014 Query: 285 GPPAVSSQPSGGRSLGEEG-PPTRGASPPTPPVSIKSERLSPA-PGGPGD 332 G P + P ++G+ G P +G P P + + SP PG GD Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064 Score = 51.2 bits (121), Expect = 1e-06 Identities = 89/338 (26%), Positives = 109/338 (32%), Gaps = 96/338 (28%) Query: 94 GLDGPELEPD-EGPE-EPGEKFRR-LAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPP 150 GL GP P G + EPG L G G+P P P P +P P + G + PP Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP---PGIQGLPGPTGIPGPIGPP 197 Query: 151 GCDPSGLGEALPAQSRPSP-------FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLP 203 G P GL P P F+ + G GL P P ++ + P + Sbjct: 198 G--PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP---ID 252 Query: 204 TEGRRSD--LPG--------GLAGPRG------------------------GLNTSRSLY 229 E ++ D LPG G+ GP G G N + Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 230 SGLQNPC---------------STATPGPP------------LGS-----FPFLPGGPPE 257 +P T PGPP +G P LPG E Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 258 YGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVS 317 G PPGL PP A GPP P G+EGPP G S P PP Sbjct: 373 RGFPGIQGPPGLPGPPGAAVM------GPPGPPGFPGERGQKGDEGPP--GISIPGPPGL 424 Query: 318 IKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGP 355 PG PG P + + EP PGP Sbjct: 425 DGQPGAPGLPGPPGPAGPHIP----PSDEICEPGPPGP 458 Score = 47.8 bits (112), Expect = 2e-05 Identities = 91/323 (28%), Positives = 110/323 (34%), Gaps = 73/323 (22%) Query: 94 GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151 G G + EP + P + GE G+ G P LP YP P G PPG Sbjct: 286 GEKGEQGEPGKRGKPGKDGEN-----GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340 Query: 152 CDPSGL-----GEALPAQSRPSPFRPAAPKA----------GPPGLVHPLFSPSHLTSKT 196 P GL G + + + P P GPPGL P P Sbjct: 341 --PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP---PGAAVMGP 395 Query: 197 PPPLYLPTE-GRRSDL--PG-GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLP 252 P P P E G++ D PG + GP G G P + PGPP + P +P Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPG--------LDG--QPGAPGLPGPPGPAGPHIP 445 Query: 253 GGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD-----------------GPPAVSSQPSG 295 E PP PPG L Q +GD G P + P Sbjct: 446 PS-DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGP 504 Query: 296 GRSLGEEGPP-TRGASPPTPPVSIKSERLSPAPGGPGDFP---------KTFPYPLLLAR 345 SLG G +G + T P + + APG PG FP TFP Sbjct: 505 PGSLGFPGQKGEKGQAGATGPKGLPG--IPGAPGAPG-FPGSKGEPGDILTFPGMKGDKG 561 Query: 346 SLAEPLRPG-PALRRLPLADGWP 367 L P PG P L P DG P Sbjct: 562 ELGSPGAPGLPGLPGTPGQDGLP 584 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 65.9 bits (159), Expect = 6e-11 Identities = 59/189 (31%), Positives = 84/189 (44%), Gaps = 22/189 (11%) Query: 148 PPPGCDPSGLGEALPAQSRPSPFRPAAPK--AGPPGL-VHPLFSPSHLTSKTPP-----P 199 PPP P G A+ AQ +P+P P+ P+ A PP L +H + + + TPP P Sbjct: 712 PPPPPPPPTPGSAM-AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIP 770 Query: 200 LYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYG 259 LP + L + P TS + + + TP PP+ P P Y Sbjct: 771 APLPPQAPPKPLV-TIPAP-----TSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI 824 Query: 260 LGDPPPPPGLLQPPTLAPWQPSRGDGPPA-VSSQPSGGRSLGEEGPPTRGASPPTPPVSI 318 PP PP + PPTL Q PP+ +S PS + + + PP PPTPP ++ Sbjct: 825 PPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPP-----PPTPP-AM 878 Query: 319 KSERLSPAP 327 +S+ L P P Sbjct: 879 ESQPLKPVP 887 Score = 48.9 bits (115), Expect = 7e-06 Identities = 56/205 (27%), Positives = 72/205 (35%), Gaps = 36/205 (17%) Query: 123 PALPRPRLYPAAPAM---PSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGP 179 P +P + PA PA PSP +PPP LP Q P +P + Sbjct: 808 PPVPPAKKQPAFPASYIPPSPPTPPVPVPPP---------TLPKQQSFCAKPPPSPLSPV 858 Query: 180 PGLVHPLFSPSHLTSKTPPPLYLPTEGRR--SDLPGGLAGPRGGLNTSRSLYSGLQNPCS 237 P +V + S+ PPP P + +P +A ++ + P S Sbjct: 859 PSVV------KQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ----PSS 908 Query: 238 TATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGR 297 P P P PPE L PPPPP P AP P P S G+ Sbjct: 909 IPVPSPDF------PPPPPESSLVFPPPPPS----PVPAPPPPPPPTASPTPDKSGSPGK 958 Query: 298 SLGEEGPPTRGASPPTPP--VSIKS 320 + P PPTP SIKS Sbjct: 959 KTSKTSSPGGKKPPPTPQRNSSIKS 983 Score = 45.8 bits (107), Expect = 6e-05 Identities = 42/131 (32%), Positives = 52/131 (39%), Gaps = 14/131 (10%) Query: 235 PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294 P + + P PPL P P PP PPPPP PP + PS G P + Sbjct: 618 PYTASQPSPPLPPPP--PPPPP------PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669 Query: 295 GGRSLGEEGPPTRGASPPTPPV----SIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEP 350 R PPTPPV S+K + L P P G P P P ++A+ Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP-PNGVVPPPPPPPPPPTPGSAMAQ- 727 Query: 351 LRPGPALRRLP 361 L+P P LP Sbjct: 728 LKPAPCAPSLP 738 Score = 42.4 bits (98), Expect = 7e-04 Identities = 59/257 (22%), Positives = 78/257 (30%), Gaps = 32/257 (12%) Query: 98 PELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYP--------------AAPAMPSPDVV 143 P P P PG +L P+LP+ P A P P P + Sbjct: 710 PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI 769 Query: 144 YGALPPPGCD--------PSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSK 195 LPP P+ P ++ +P P P PP P F S++ Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV--PPAKKQPAFPASYIPPS 827 Query: 196 TP-PPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGG 254 P PP+ +P P L+ S+ + + P + S P P Sbjct: 828 PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV- 886 Query: 255 PPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTP 314 P P PP + P WQPS P P SL PP P P Sbjct: 887 PANVA---PQSPPAVKAKPK---WQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940 Query: 315 PVSIKSERLSPAPGGPG 331 P + G PG Sbjct: 941 PPPPTASPTPDKSGSPG 957 Score = 40.4 bits (93), Expect = 0.003 Identities = 61/224 (27%), Positives = 79/224 (35%), Gaps = 50/224 (22%) Query: 137 MPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKT 196 M S + Y +L PP + A S+PSP P P PP P Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTA-SQPSPPLPPPPPPPPPPPPPP----------P 643 Query: 197 PPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTA-----TPGPPLGSFPFL 251 PPP LP++ S AG + S + LQN + P PP+ + Sbjct: 644 PPPPPLPSQSAPS------AGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV 697 Query: 252 PGG---PPEYGLGDPPPPP---------GLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSL 299 PP + PPPPP L+P AP P PP + + + Sbjct: 698 KPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV--QHI 755 Query: 300 GEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPK---TFPYP 340 + PPT PP PP+ PAP P PK T P P Sbjct: 756 TQVAPPT---PPPPPPI--------PAPLPPQAPPKPLVTIPAP 788 Score = 38.9 bits (89), Expect = 0.007 Identities = 59/214 (27%), Positives = 71/214 (33%), Gaps = 28/214 (13%) Query: 135 PAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP-----------GLV 183 P PSP PPP P+ P + P K P G Sbjct: 929 PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAE 988 Query: 184 HP---LFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGG-LNTSRSLYSG-LQNPCST 238 HP S L SK PP + + + LP A P+ G LN S G LQ C + Sbjct: 989 HPEPKRPSVDSLVSKFTPPAESGSPSKET-LPPPAAPPKPGKLNLSGVNLPGVLQQGCVS 1047 Query: 239 ATP----GPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGP--PAVSSQ 292 A G S P P + PPP L PP P S P V+ Q Sbjct: 1048 AKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQ 1107 Query: 293 PSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326 P + + A PPT P S RL+ A Sbjct: 1108 PQQWSKMS-----VKKAPPPTRPKRNDSTRLTQA 1136 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 65.9 bits (159), Expect = 6e-11 Identities = 66/240 (27%), Positives = 79/240 (32%), Gaps = 34/240 (14%) Query: 121 GDPALPRPRLYPAAPAMPSPDVVYG---------ALPPPGCDPSGLGEALPAQSRPSPFR 171 G PA P P+ P PA P G PP PS G + +P Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011 Query: 172 PAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPT-EGRRSDLPGGLAGPRGGLNTSRSLYS 230 PA P G P +P + TPP P+ +G + P P T S Sbjct: 1012 PAVTPPSPKG--SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069 Query: 231 GLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRG------- 283 G P P PP + P GGP P P G PP P P G Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPA------TPSPKGAPMPPAATPPSPKGGLATPPHK 1123 Query: 284 ---DGPPAVSSQPSGGRSLGEEGPPTRGA--SPPTPPVSIKSERLSPAPGGPGDFPKTFP 338 P A P GG + PP +GA +P P S K +P P G P P Sbjct: 1124 GAPTTPAATPPSPKGGLAT----PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179 Score = 65.9 bits (159), Expect = 6e-11 Identities = 70/253 (27%), Positives = 83/253 (32%), Gaps = 39/253 (15%) Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPF---------- 170 G A P P+ P PA P G P P G PA + PSP Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATP---SPKG-APTTPAATPPSPKGGLATPSPKG 1216 Query: 171 RPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYS 230 P P A PP L +PS + T P P+ P P T SL Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276 Query: 231 GLQNPCSTATPGPPLGSFPFLPGGP---PEYGLGDP--------------PPPPGLLQPP 273 GL P P P + + P GGP P G P PPP G PP Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336 Query: 274 TLAPWQPSRGDGPPAVSSQPSGGRSL--GEEGP------PTRGASPPTPPVSIKSERLSP 325 + P P PA + GG + +EGP P+ P P S K P Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396 Query: 326 APGGPGDFPKTFP 338 +P G P P Sbjct: 1397 SPKGDPTSPAVIP 1409 Score = 61.6 bits (148), Expect = 1e-09 Identities = 86/301 (28%), Positives = 107/301 (35%), Gaps = 83/301 (27%) Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGC-----------DPSGLGEALPAQSRPSP 169 G PA P P+ P PA P + G PP P G P + P+P Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312 Query: 170 --FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRS 227 P +PK G PG P +P TPP + P+ LP +GG T Sbjct: 1313 PAATPPSPK-GSPGTPPPKGAP------TPPAVTPPSPKGTPTLPATTPSSKGGPTT--- 1362 Query: 228 LYSGLQNPCSTATPGPPLGSFPFLPGGP------PEYG------LGDPPPPPGLLQPPTL 275 P S P PP + P GGP P+ G GDP P + P Sbjct: 1363 -------PSSKEGPTPPAAT-PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414 Query: 276 APWQP---------SRGD-GPPAVS----------SQPSGGRSL-GEEGPPTRGA----S 310 AP P S+GD PPAV+ S P GG + +G PT A S Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474 Query: 311 PPTPPV--------SIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRLPL 362 P PP S K +PAP G P P S + + P+ RR P+ Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP-------SSPKEVPATPSSRRDPI 1527 Query: 363 A 363 A Sbjct: 1528 A 1528 Score = 59.3 bits (142), Expect = 5e-09 Identities = 76/270 (28%), Positives = 93/270 (34%), Gaps = 33/270 (12%) Query: 119 EGGDPALPRPRLYPAAPA--MPSPD------VVYGA-LPPPGCDPSGLGEALPAQSRPSP 169 +G A P P+ P PA +PSP + GA PP PS G + +P Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103 Query: 170 FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLY 229 PAA P G L +P H + T P P+ P P T S Sbjct: 1104 MPPAATPPSPKG---GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160 Query: 230 SGLQNP-------CSTATPGPPLGSFPF-LPGGPPEYGLGDPPPPPGLLQPPTLAPWQPS 281 GL P ATP P G P G P PP P G L P+ Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS----PKG 1216 Query: 282 RGDGPPAVSSQPSGGRSL--GEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPY 339 P A P GG + + P T A+PP+P K +P P G P P Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP----KGGPATPPPKGAPTPPAATP- 1271 Query: 340 PLLLARSLAEPLR--PGPALRRLPLADGWP 367 P L P + P PA+ P G P Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301 Score = 52.8 bits (125), Expect = 5e-07 Identities = 61/221 (27%), Positives = 73/221 (33%), Gaps = 29/221 (13%) Query: 132 PAAPAMPSPDVVYGALPPPGCDP-SGLGEALPAQSRPSP--FRPAAPKAGP--------P 180 PA P+P GA P P S G LP + P+P PK GP P Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909 Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240 L SP + TP P +P P P T S G P Sbjct: 910 ALSMTSSSPKKARA-TPAPKGIPAS------PSPKGAPTPPAATPPSPKGGPATPSPKWA 962 Query: 241 PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLG 300 P PP + P GGP P P G PP P P G P+ P G + Sbjct: 963 PTPPAATPPSPKGGPAT------PSPKGAPTPPAATPPSPKGGPATPS----PKGAPTPP 1012 Query: 301 EEGPPT-RGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYP 340 PP+ +G+ TP S + P P P P P Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053 Score = 52.8 bits (125), Expect = 5e-07 Identities = 64/228 (28%), Positives = 78/228 (34%), Gaps = 27/228 (11%) Query: 102 PDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEAL 161 P GP P K GDP LP P+ P+P V + P + Sbjct: 1452 PKGGPATPSSK--------GDPTLPAVTP-PSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502 Query: 162 PAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGG 221 P P P A P P+ + L SK P P E +P + P Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL---IPPAMTVP--- 1556 Query: 222 LNTSRSLYSGLQNPCST-ATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQP 280 S + P ATP S P P P G P P LL PP + P Sbjct: 1557 ---SPKKTPAIPTPKEAPATPSSKEASSP--PAVTPSTYKGAPSPKE-LLIPPAVTSPSP 1610 Query: 281 SRGDGPPAVS--SQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326 PPAV+ S G + +G PT SPP P S+K SPA Sbjct: 1611 KEAPTPPAVTPPSPEKGPATPAPKGTPT---SPPVTPSSLKDSPTSPA 1655 Score = 52.4 bits (124), Expect = 6e-07 Identities = 56/211 (26%), Positives = 72/211 (34%), Gaps = 37/211 (17%) Query: 125 LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVH 184 LP P+ PA PA P + + P ++R +P APK P Sbjct: 893 LPFPKEGPATPA------------PKQAPALSMTSSSPKKARATP----APKGIPA---- 932 Query: 185 PLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPP 244 SPS + TPP P+ P P T S G P P PP Sbjct: 933 ---SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP 989 Query: 245 LGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGP 304 + P GGP P P G PP + P P G PA + P G + P Sbjct: 990 AATPPSPKGGPA------TPSPKGAPTPPAVTPPSPK---GSPAATPFPKGASTPPAATP 1040 Query: 305 PTRGASPPTPPV-----SIKSERLSPAPGGP 330 P+ SP P+ + + L GGP Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071 Score = 36.6 bits (83), Expect = 0.037 Identities = 64/229 (27%), Positives = 85/229 (37%), Gaps = 30/229 (13%) Query: 130 LYPAAP-AMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAA--PKAGPP---GLV 183 L P P ++PSP +LPP G P + + S S P A PK P G Sbjct: 726 LAPEIPKSVPSP-----SLPPAGTPPGT--KKVDGISHTSALAPVASSPKECPTEDSGAS 778 Query: 184 HPLFSPSHLT----SKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTA 239 S LT S +P + + + +R G AGP + S S ++ ++ Sbjct: 779 ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE---ASF 835 Query: 240 TPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS-GGRS 298 P L SF P PP P G P + P P PP + PS Sbjct: 836 LPENSL-SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP 894 Query: 299 LGEEGPPTRGASPPTPPVSI-----KSERLSPAPGG--PGDFPKTFPYP 340 +EGP T A P +S+ K R +PAP G PK P P Sbjct: 895 FPKEGPAT-PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 64.7 bits (156), Expect = 1e-10 Identities = 84/264 (31%), Positives = 94/264 (35%), Gaps = 36/264 (13%) Query: 95 LDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDP 154 L G E+ P P PG G LP P L P A P P + A+PPP P Sbjct: 902 LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPL-PGAGIPPPPPLPGAAIPPPPPLP 960 Query: 155 SG---LGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL 211 L LP P P P P AG P P + PPP LP G + Sbjct: 961 GAGIPLPPPLPGAGIPPP--PPLPGAGIPP------PPPLPGAGIPPPPPLPGAG----I 1008 Query: 212 PGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGG-----PPEYGLGDPPPP 266 P P G+ L G P PG + P LPG PP G G PPPP Sbjct: 1009 PPPPPLPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1067 Query: 267 P----GLLQPPTL-----APWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVS 317 P G+ PP L P P G G P P G PP GA P PP Sbjct: 1068 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI---PPPPPLPGAGIPPPP-P 1123 Query: 318 IKSERLSPAPGGPG-DFPKTFPYP 340 + + P P PG P P P Sbjct: 1124 LPGAGIPPPPPLPGAGIPPPPPLP 1147 Score = 61.2 bits (147), Expect = 1e-09 Identities = 87/293 (29%), Positives = 103/293 (35%), Gaps = 43/293 (14%) Query: 92 GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151 G G+ P P G P L G G +P P P A P P + +PPP Sbjct: 983 GAGIPPPPPLPGAGIPPPPP----LPGAG----IPPPPPLPGAGIPPPPPLPGAGIPPPP 1034 Query: 152 CDP-SGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSD 210 P +G+ P P P P AG P P + PPP LP G Sbjct: 1035 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP------PPPLPGAGIPPPPPLPGAG---- 1084 Query: 211 LPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGG-----PPEYGLGDPPP 265 +P P G+ L G+ P PG + P LPG PP G G PPP Sbjct: 1085 IPPPPPLPGAGIPPPPPL-PGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1143 Query: 266 PP----GLLQPPTLA-----PWQPSRGDGPPAVSSQPSGG-------RSLGEEGPPTRGA 309 PP G+ PP L P P G G P P G +G PP Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPG 1203 Query: 310 SPPTPPVSIKSERLSPAPGGPGDFPKT-FPYPLLLARSLAEPLRPGPALRRLP 361 + PP + + PAP P P T P P LL S PL P LP Sbjct: 1204 AGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVS-GPPLLPQVGSSTLP 1255 Score = 57.4 bits (137), Expect = 2e-08 Identities = 75/236 (31%), Positives = 87/236 (36%), Gaps = 36/236 (15%) Query: 92 GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151 G G+ P P G P L G G +P P P A P P + +PPP Sbjct: 1049 GAGIPPPPPLPGAGIPPPPP----LPGAG----IPPPPPLPGAGIPPPPPLPGAGIPPPP 1100 Query: 152 CDPSGLG----EALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGR 207 P G+G LP P P P P AG P P + PPP LP G Sbjct: 1101 PLP-GVGIPPPPPLPGAGIPPP--PPLPGAGIPP------PPPLPGAGIPPPPPLPRVG- 1150 Query: 208 RSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPG-----GPPEYGLGD 262 +P P G+ L G P PG + P LPG PP G G Sbjct: 1151 ---IPPPPPLPGAGIPPPPPL-PGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGI 1206 Query: 263 PPPPP--GLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPV 316 PPPPP G+ PP AP P G G P P G L P ++ PTP V Sbjct: 1207 PPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPL---LPQVGSSTLPTPQV 1259 Score = 50.1 bits (118), Expect = 3e-06 Identities = 68/228 (29%), Positives = 79/228 (34%), Gaps = 35/228 (15%) Query: 125 LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVH 184 +P P P + S + PPP P LP+ + P P P G L Sbjct: 855 IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQP----PPLQGTEMLPP 910 Query: 185 PLFSPSHLTSKTPPPLYLPTEG--RRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPG 242 P P + PPP LP G LPG P L P + P Sbjct: 911 P--PPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL------------PGAAIPPP 956 Query: 243 PPLGSFPFLPGGPPEYGLGDPPPPP----GLLQPPTL-----APWQPSRGDGPPAVSSQP 293 PPL +P PP G G PPPPP G+ PP L P P G G P P Sbjct: 957 PPLPGAG-IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015 Query: 294 SGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPG-DFPKTFPYP 340 G PP GA P PP + + P P PG P P P Sbjct: 1016 GAGI---PPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLP 1059 Score = 38.5 bits (88), Expect = 0.010 Identities = 52/204 (25%), Positives = 67/204 (32%), Gaps = 28/204 (13%) Query: 161 LPAQSRPSPFRPAAPKAGPPGLVHP-----------LFSPSHLTSKTP-PPLYLPTEGRR 208 L Q + + A A PP V P L PS + P P Sbjct: 217 LQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSAL 276 Query: 209 SDLPGGLAG-PR--------GGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYG 259 SDLP LA PR GGL S + P + +P +FPF GP E Sbjct: 277 SDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSST--AFPFPEAGPGEEA 334 Query: 260 LGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIK 319 G P G T + + P S +GE+ P G P Sbjct: 335 AGAPVRGAG----DTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPD 390 Query: 320 SERLSPAPGGPGDFPKTF-PYPLL 342 + + PG P + F PYPL+ Sbjct: 391 APAAASLPGSPAPSQRCFKPYPLI 414 Score = 29.3 bits (64), Expect = 5.9 Identities = 26/101 (25%), Positives = 37/101 (36%), Gaps = 5/101 (4%) Query: 256 PEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPP-AVSSQPSGGRSLGEEGPPTRGASPPTP 314 P + PPPPP LL + Q G PP ++S++ + P+P Sbjct: 803 PTQSISQPPPPPSLL----WSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP 858 Query: 315 PVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGP 355 P +E S PG P P P + +L P P Sbjct: 859 PPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQP 899 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 64.7 bits (156), Expect = 1e-10 Identities = 79/251 (31%), Positives = 91/251 (36%), Gaps = 40/251 (15%) Query: 94 GLDGPELEPDEG-PEEPGEKFRRLAG-----------EG--GDPALPRPRLYPAAPAMPS 139 GL GP P G P PG K R G +G G P + P P P +P Sbjct: 340 GLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPG 399 Query: 140 PDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP- 198 P GA+ PG P G G + Q P P G PGL P L PP Sbjct: 400 PMGPPGAIGFPG--PKGEGGIVGPQGPPGP-------KGEPGLQGFPGKPGFLGEVGPPG 450 Query: 199 ------PLYLPTEGRRSDLPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGS 247 P+ E + +PG GL GP+G GLQ P G P G Sbjct: 451 MRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGD--QGLQGPPGIPGIGGPSGP 508 Query: 248 F--PFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPP 305 P +PG E GL PP PG+ +P P G QP G GPP Sbjct: 509 IGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPP 568 Query: 306 TRGA-SPPTPP 315 A PPTPP Sbjct: 569 GPPAVMPPTPP 579 Score = 52.0 bits (123), Expect = 8e-07 Identities = 79/279 (28%), Positives = 99/279 (35%), Gaps = 56/279 (20%) Query: 86 ETLKRRGIGLDGPELEPDEGPE-EPGEKFRRLAGEGGDPALPR-----------PRLYPA 133 E + ++G + L ++GP EPG + G G P LP P+ YP Sbjct: 102 EAVPKKGKEIPLASLRGEQGPRGEPGPR-----GPPGPPGLPGHGIPGIKGKPGPQGYPG 156 Query: 134 A--PAMPSPDVVYGALPPPGCDPS-GLGEALPAQSRPSPFRPAAP-------KAGPPGLV 183 P MP GA+ PG G + P P P P K G PGL Sbjct: 157 VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLP 216 Query: 184 HPLFSPSHLTSKTPPPLYLPT--EGRRSD----LPG--GLAGPRGGLNTSRSL-YSGLQN 234 P + P L P G + D +PG G+ GP G + G+ Sbjct: 217 G---QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGK 273 Query: 235 PCSTATPGP--PLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ 292 P T PGP PLG PG P E G P PG+ PP + DG P Sbjct: 274 PGVTGFPGPQGPLGK----PGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGF 329 Query: 293 PSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPG 331 P G GE+G P P P + PG PG Sbjct: 330 PGG---KGEQGLPGLPGPPGLPGIG--------KPGFPG 357 Score = 45.8 bits (107), Expect = 6e-05 Identities = 69/248 (27%), Positives = 84/248 (33%), Gaps = 53/248 (21%) Query: 97 GPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDV--VYGALPP---PG 151 G E P +G E P L GE G P PR P P +P + + G P PG Sbjct: 100 GKEAVPKKGKEIP---LASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPG 156 Query: 152 CDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL 211 G+ +P + A + G G + P+ P P P LP G+ Sbjct: 157 VGKPGM-PGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG--PQGPPGPHGLPGIGKPGG- 212 Query: 212 PG--GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLG-SFPFLPG--GPPEYGLGDPPPP 266 PG G GP+G GL P P G P PG GPP G+ PP P Sbjct: 213 PGLPGQPGPKGDRGPK-----GLPGPQGLRGPKGDKGFGMPGAPGVKGPP--GMHGPPGP 265 Query: 267 PGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326 GL G G P V+ P LG+ G P P Sbjct: 266 VGL------------PGVGKPGVTGFPGPQGPLGKPGAPGE-----------------PG 296 Query: 327 PGGPGDFP 334 P GP P Sbjct: 297 PQGPIGVP 304 Score = 44.3 bits (103), Expect = 2e-04 Identities = 75/259 (28%), Positives = 90/259 (34%), Gaps = 58/259 (22%) Query: 92 GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAA--PAMPSPDVVYGALPP 149 GIG G + P + P PG K GE G P LP P P P P P G Sbjct: 314 GIGKPGQDGIPGQ-PGFPGGK-----GEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367 Query: 150 PGC-DPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRR 208 PG P G + A P P P G PG+ P+ PP + G + Sbjct: 368 PGALGPRGEKGPIGAPGIGGP--PGEP--GLPGIPGPM----------GPPGAIGFPGPK 413 Query: 209 SDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPG 268 + GG+ GP+G P PG L FP PG E G PP G Sbjct: 414 GE--GGIVGPQGP-------------PGPKGEPG--LQGFPGKPGFLGEVG---PPGMRG 453 Query: 269 LLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGE---------EGPP----TRGASPPTPP 315 L P + P + G P + P GE +GPP G S P P Sbjct: 454 L--PGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGP 511 Query: 316 VSIKSERLSPAPGGPGDFP 334 I + P GP FP Sbjct: 512 PGIPGPKGEPGLPGPPGFP 530 Score = 37.0 bits (84), Expect = 0.028 Identities = 33/106 (31%), Positives = 40/106 (37%), Gaps = 17/106 (16%) Query: 94 GLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPP-GC 152 GL GP P +PG G G P LP P P P P P V PPP G Sbjct: 539 GLHGP-------PGKPGA-----LGPQGQPGLPGP---PGPPGPPGPPAVMPPTPPPQGE 583 Query: 153 DPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP 198 +G + P + K G P P F+ + LT+ PP Sbjct: 584 YLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFT-AELTAPFPP 628 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 64.7 bits (156), Expect = 1e-10 Identities = 79/251 (31%), Positives = 91/251 (36%), Gaps = 40/251 (15%) Query: 94 GLDGPELEPDEG-PEEPGEKFRRLAG-----------EG--GDPALPRPRLYPAAPAMPS 139 GL GP P G P PG K R G +G G P + P P P +P Sbjct: 340 GLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPG 399 Query: 140 PDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP- 198 P GA+ PG P G G + Q P P G PGL P L PP Sbjct: 400 PMGPPGAIGFPG--PKGEGGIVGPQGPPGP-------KGEPGLQGFPGKPGFLGEVGPPG 450 Query: 199 ------PLYLPTEGRRSDLPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGS 247 P+ E + +PG GL GP+G GLQ P G P G Sbjct: 451 MRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGD--QGLQGPPGIPGIGGPSGP 508 Query: 248 F--PFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPP 305 P +PG E GL PP PG+ +P P G QP G GPP Sbjct: 509 IGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPP 568 Query: 306 TRGA-SPPTPP 315 A PPTPP Sbjct: 569 GPPAVMPPTPP 579 Score = 52.0 bits (123), Expect = 8e-07 Identities = 79/279 (28%), Positives = 99/279 (35%), Gaps = 56/279 (20%) Query: 86 ETLKRRGIGLDGPELEPDEGPE-EPGEKFRRLAGEGGDPALPR-----------PRLYPA 133 E + ++G + L ++GP EPG + G G P LP P+ YP Sbjct: 102 EAVPKKGKEIPLASLRGEQGPRGEPGPR-----GPPGPPGLPGHGIPGIKGKPGPQGYPG 156 Query: 134 A--PAMPSPDVVYGALPPPGCDPS-GLGEALPAQSRPSPFRPAAP-------KAGPPGLV 183 P MP GA+ PG G + P P P P K G PGL Sbjct: 157 VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLP 216 Query: 184 HPLFSPSHLTSKTPPPLYLPT--EGRRSD----LPG--GLAGPRGGLNTSRSL-YSGLQN 234 P + P L P G + D +PG G+ GP G + G+ Sbjct: 217 G---QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGK 273 Query: 235 PCSTATPGP--PLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ 292 P T PGP PLG PG P E G P PG+ PP + DG P Sbjct: 274 PGVTGFPGPQGPLGK----PGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGF 329 Query: 293 PSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPG 331 P G GE+G P P P + PG PG Sbjct: 330 PGG---KGEQGLPGLPGPPGLPGIG--------KPGFPG 357 Score = 45.8 bits (107), Expect = 6e-05 Identities = 69/248 (27%), Positives = 84/248 (33%), Gaps = 53/248 (21%) Query: 97 GPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDV--VYGALPP---PG 151 G E P +G E P L GE G P PR P P +P + + G P PG Sbjct: 100 GKEAVPKKGKEIP---LASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPG 156 Query: 152 CDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL 211 G+ +P + A + G G + P+ P P P LP G+ Sbjct: 157 VGKPGM-PGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG--PQGPPGPHGLPGIGKPGG- 212 Query: 212 PG--GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLG-SFPFLPG--GPPEYGLGDPPPP 266 PG G GP+G GL P P G P PG GPP G+ PP P Sbjct: 213 PGLPGQPGPKGDRGPK-----GLPGPQGLRGPKGDKGFGMPGAPGVKGPP--GMHGPPGP 265 Query: 267 PGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326 GL G G P V+ P LG+ G P P Sbjct: 266 VGL------------PGVGKPGVTGFPGPQGPLGKPGAPGE-----------------PG 296 Query: 327 PGGPGDFP 334 P GP P Sbjct: 297 PQGPIGVP 304 Score = 44.3 bits (103), Expect = 2e-04 Identities = 75/259 (28%), Positives = 90/259 (34%), Gaps = 58/259 (22%) Query: 92 GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAA--PAMPSPDVVYGALPP 149 GIG G + P + P PG K GE G P LP P P P P P G Sbjct: 314 GIGKPGQDGIPGQ-PGFPGGK-----GEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367 Query: 150 PGC-DPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRR 208 PG P G + A P P P G PG+ P+ PP + G + Sbjct: 368 PGALGPRGEKGPIGAPGIGGP--PGEP--GLPGIPGPM----------GPPGAIGFPGPK 413 Query: 209 SDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPG 268 + GG+ GP+G P PG L FP PG E G PP G Sbjct: 414 GE--GGIVGPQGP-------------PGPKGEPG--LQGFPGKPGFLGEVG---PPGMRG 453 Query: 269 LLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGE---------EGPP----TRGASPPTPP 315 L P + P + G P + P GE +GPP G S P P Sbjct: 454 L--PGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGP 511 Query: 316 VSIKSERLSPAPGGPGDFP 334 I + P GP FP Sbjct: 512 PGIPGPKGEPGLPGPPGFP 530 Score = 37.0 bits (84), Expect = 0.028 Identities = 33/106 (31%), Positives = 40/106 (37%), Gaps = 17/106 (16%) Query: 94 GLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPP-GC 152 GL GP P +PG G G P LP P P P P P V PPP G Sbjct: 539 GLHGP-------PGKPGA-----LGPQGQPGLPGP---PGPPGPPGPPAVMPPTPPPQGE 583 Query: 153 DPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP 198 +G + P + K G P P F+ + LT+ PP Sbjct: 584 YLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFT-AELTAPFPP 628 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 64.3 bits (155), Expect = 2e-10 Identities = 76/260 (29%), Positives = 86/260 (33%), Gaps = 41/260 (15%) Query: 108 EPGEK-FRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCD--PSGLGEALPAQ 164 EPGE R G GDP LP P P G PG D P G A Sbjct: 1258 EPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRA---- 1313 Query: 165 SRPSPFRPAAPKA-GPPGLVHPLFSPSHLTSKTP------PPLYLPTEG-----RRSDL- 211 +P P AP G PGL P P + P P + EG R+ D Sbjct: 1314 --GNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPG 1371 Query: 212 PGGLAGPRGGLNT----------SRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLG 261 P G GPRG L ++ + PGP G PG P GL Sbjct: 1372 PSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIA--PGEPGLPGLP 1429 Query: 262 DPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPP-------TRGASPPTP 314 P P G + PP + DG P + QP G GPP RG P Sbjct: 1430 GSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLG 1489 Query: 315 PVSIKSERLSPAPGGPGDFP 334 K ER P P G P Sbjct: 1490 EAGEKGERGPPGPAGSRGLP 1509 Score = 52.4 bits (124), Expect = 6e-07 Identities = 69/240 (28%), Positives = 89/240 (37%), Gaps = 34/240 (14%) Query: 118 GEGGDPALPRPRLYPAAPAMPSPDVVYGALPP--PGCDPSGLGEALPAQSRPSPFRPAAP 175 G G+P P +P +P P G P P +P G+ + + P R P Sbjct: 1311 GRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDP 1370 Query: 176 -KAGPPGLVHPLFSPSHLTSKTPPPLY-LPTEGRRSDL-PGGLAGP-RGGLNTSRSLYSG 231 +GPPG PL P + PP L +G + D G GP GG+ G Sbjct: 1371 GPSGPPGPRGPLGDPG---PRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPG 1427 Query: 232 LQ-NPCSTATPGPP---------LGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPS 281 L +P GPP P LPG P G P PPG + P + Sbjct: 1428 LPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGP 1487 Query: 282 RGD-------GPPAVSSQPSGGRSL-GEEGPP-TRGASPPTPPVSIKSERLSPAPGGPGD 332 G+ GPP P+G R L G G P +G P P + E+ PG PGD Sbjct: 1488 LGEAGEKGERGPPG----PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEK--GEPGRPGD 1541 Score = 48.1 bits (113), Expect = 1e-05 Identities = 93/331 (28%), Positives = 107/331 (32%), Gaps = 100/331 (30%) Query: 94 GLDGPELEPDE----GPE-EPGEKFRRLAGEG-------GDPAL------------PRPR 129 GL GP +P E GP+ EPG + + GEG GDP P PR Sbjct: 1329 GLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPR 1388 Query: 130 LYPAAP--AMPSPDVVYGALPPPGCDPSGLGEALPA----QSRPSPFRPAAPKA------ 177 P P AM G PPG G+ P P P P P Sbjct: 1389 GPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG 1448 Query: 178 ----GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRG-----GLNTSRSL 228 G PGL SP + PP P R P G AG +G G SR L Sbjct: 1449 DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGL 1508 Query: 229 YSGLQNPCSTATPGPPLGSF-------PFLPGGP---------PEYGLGDPPP------- 265 P + GPP + P PG P P+ GD P Sbjct: 1509 PGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGAT 1568 Query: 266 -------PPGLLQPPTLAPWQPSRGD----------GPPAVSSQPSGGRSLGEEGPPTRG 308 PPGL+ P P + GD GPP S P GE+G P R Sbjct: 1569 GVQGERGPPGLVLPGDPGP-KGDPGDRGPIGLTGRAGPPGDSGPP------GEKGDPGRP 1621 Query: 309 ASP-PTPP------VSIKSERLSPA-PGGPG 331 P P P V K + P PG PG Sbjct: 1622 GPPGPVGPRGRDGEVGEKGDEGPPGDPGLPG 1652 Score = 47.0 bits (110), Expect = 3e-05 Identities = 66/209 (31%), Positives = 80/209 (38%), Gaps = 29/209 (13%) Query: 151 GCDPSGLGEALPAQSRPSPFRPAAPKAGPP------GLVHPLFSPSHLTSKTPPP--LYL 202 G DP L P F A GP GL L S T P P +Y Sbjct: 1194 GADPEQLRRLAPGMDSVQTF--FAVDDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYC 1251 Query: 203 PTEGRRSDLPG-----GLAGPRG--GLNTSRSLYSGLQNPCSTATPGPPLGSFPFL---P 252 P +G++ + PG G GP G GL R+ G Q P +AT G FP P Sbjct: 1252 P-KGQKGE-PGEMGLRGQVGPPGDPGL-PGRTGAPGPQGPPGSATAKGERG-FPGADGRP 1307 Query: 253 GGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD-GPPAVSSQPSG-GRSLGEEGP--PTRG 308 G P G P PGL P L + G+ GP +P G+ +G EGP P R Sbjct: 1308 GSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRK 1367 Query: 309 ASP-PTPPVSIKSERLSPAPGGPGDFPKT 336 P P+ P + P P GP P T Sbjct: 1368 GDPGPSGPPGPRGPLGDPGPRGPPGLPGT 1396 Score = 46.6 bits (109), Expect = 4e-05 Identities = 77/262 (29%), Positives = 91/262 (34%), Gaps = 40/262 (15%) Query: 94 GLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCD 153 GL G + EP ++ + R + G GD P PR P +P + G PG Sbjct: 2111 GLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQ 2170 Query: 154 -PSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL 211 P G + P P P AP AGP G P PP L L Sbjct: 2171 GPRGPPGPVGGHGDPGP--PGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGL 2228 Query: 212 PG-----GLAGPRGGLNTSRSLYSGLQNPC-STATPGPP-----------LGSFPFLPGG 254 PG GL GP+G GL T PG P GS P +PG Sbjct: 2229 PGPPGPSGLVGPQGS--------PGLPGQVGETGKPGAPGRDGASGKDGDRGS-PGVPGS 2279 Query: 255 PPEYGLGDPPPPPGLLQPPTLAPWQPSRG-DGPPAVSSQPSG--GRSLGEEGPPTRGASP 311 P G P PG PT AP Q G G P G G +GE P +G Sbjct: 2280 PGLPGPVGPKGEPG----PTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE--PGAKGDRG 2333 Query: 312 PTPPVSIKSER-LSPAPGGPGD 332 P K E + PG PG+ Sbjct: 2334 LPGPRGEKGEAGRAGEPGDPGE 2355 Score = 45.8 bits (107), Expect = 6e-05 Identities = 79/298 (26%), Positives = 100/298 (33%), Gaps = 62/298 (20%) Query: 94 GLDGPELEPDEG-PEEPG----EKFRRLAGEGGDPALPRPRLYPAAP-AMPSPDVVYGAL 147 GL GP P +G P PG + R G G+ LP R P ++P+ D + L Sbjct: 1890 GLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRL---L 1946 Query: 148 PPPGCDPSGLGEALPAQSR------PSPFRPAAPKA-----GPPGLVHPLFSPSH----- 191 G S L E + P P R PK GPPG P+ P Sbjct: 1947 ETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKG 2006 Query: 192 --------------LTSKTPP-PLYLPTEGRRSDLPG-----------GLAGPRG--GLN 223 L + PP P L E + +PG G G RG G Sbjct: 2007 DRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEK 2066 Query: 224 TSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLL----QPPTLAPWQ 279 R P TPGPP P + P GL PPGL +P + Sbjct: 2067 GERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQG 2126 Query: 280 PSRGDGPPAVSSQPSGGRSLGEEG----PPTRGASPPTPPVSIKSERLSPAP-GGPGD 332 P G P + G++G P RG + P ++ R P P GG GD Sbjct: 2127 PKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGD 2184 Score = 43.1 bits (100), Expect = 4e-04 Identities = 80/305 (26%), Positives = 99/305 (32%), Gaps = 84/305 (27%) Query: 94 GLDGPELEPDEGPEEPGEK----FRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPP 149 G GP+ +P P PGE+ FR G GDP + P G P Sbjct: 1728 GPRGPKGDPGL-PGAPGERGIEGFRGPPGPQGDPGVR------------GPAGEKGDRGP 1774 Query: 150 PGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGL--VHPLFSPSHLTSKTPPPLYLPTEGR 207 PG D + P + PS AA KAG PG + L L + PP LP + Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP-GLPGKPG 1833 Query: 208 RSDLPG-----------------------------GLAGPRGGLNTSRSLYSGLQNPCST 238 PG G GP+G L G Q P Sbjct: 1834 EDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGIL--GPQGPPGL 1891 Query: 239 ATP-GPPLGSFPFLPGG------------------PPEYGL-GDPPPPPG---LLQP--- 272 P GPP FP +PGG P E GL G+P P LL+ Sbjct: 1892 PGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGI 1951 Query: 273 ------PTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTP-PVSIKSERLSP 325 + W S G P + GE+GPP + P +K +R P Sbjct: 1952 KASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDP 2011 Query: 326 APGGP 330 P GP Sbjct: 2012 GPQGP 2016 Score = 41.2 bits (95), Expect = 0.001 Identities = 66/244 (27%), Positives = 78/244 (31%), Gaps = 66/244 (27%) Query: 94 GLDGPELEPDEGPE--EPGEKFRRLAGEGGDPALPRPRLY--------PAAPAMPSPDVV 143 GL GP E E EPG+ GE G P P+ + P +P P P V Sbjct: 2333 GLPGPRGEKGEAGRAGEPGDP-----GEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGV 2387 Query: 144 YGALPPPGCDPSGLGEALPAQS---------RPSPFRPAAPKAGPPGLVHPLFSPSHLTS 194 G L PG + P Q+ PS R A G G+ PL P S Sbjct: 2388 KGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGS 2447 Query: 195 KTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGG 254 PP +G + D GL GPRG PG Sbjct: 2448 VGPPGA-SGLKGDKGDPGVGLPGPRGERGE---------------------------PGI 2479 Query: 255 PPEYGLGDPPPPPGLLQPPTLAPWQPSRGD----------GPPAVSSQPSGGR----SLG 300 E G P GL PP + +GD G AV P G R +G Sbjct: 2480 RGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMG 2539 Query: 301 EEGP 304 E GP Sbjct: 2540 ERGP 2543 Score = 36.6 bits (83), Expect = 0.037 Identities = 79/305 (25%), Positives = 94/305 (30%), Gaps = 114/305 (37%) Query: 106 PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEA----L 161 P E G R L G G LP P P P + G PG P +GE Sbjct: 2209 PGETGPPGRGLTGPTGAVGLPGP---------PGPSGLVGPQGSPGL-PGQVGETGKPGA 2258 Query: 162 PAQS--------RPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPG 213 P + R SP P +P G PG V P P + + LP PG Sbjct: 2259 PGRDGASGKDGDRGSPGVPGSP--GLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPG 2316 Query: 214 GLAG----------------PRGGLNTSRSLYS----------------------GLQNP 235 GLAG PRG + G+ P Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP 2376 Query: 236 CSTATPGPP-----LGSFPFLPGGPP---------------------EYGLGDPPP---- 265 S PGPP LG P LPG P E GL PP Sbjct: 2377 GSPGPPGPPGVKGDLG-LPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI 2435 Query: 266 --------PPGLLQPPTLAPWQPSRGD------GPPAVSSQP----SGGRSLGEEGPPTR 307 PPG + PP + + +GD GP +P GR G+EGP R Sbjct: 2436 PGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRP-GQEGP--R 2492 Query: 308 GASPP 312 G + P Sbjct: 2493 GLTGP 2497 Score = 36.2 bits (82), Expect = 0.048 Identities = 74/270 (27%), Positives = 92/270 (34%), Gaps = 63/270 (23%) Query: 93 IGLDGPE-LEPDEGPE-------------EPGEK-------FRRLAGEGGDPALPRPRLY 131 +G GP L+ D+GP EPG+K R L G G P Sbjct: 2538 MGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAG---I 2594 Query: 132 PAAPAMPSPDVVYGALPPPG----CDPSGL-GE-ALPAQSRPSPFRPAAPKAGPPGLVHP 185 P P P D V G G P GL GE + + +AGPPG Sbjct: 2595 PGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGL 2654 Query: 186 LFSPSHLTSKTPPPLYLPTEGRRSDLPG--GLAGPRG--GLNTSRSLYSGLQNPCSTATP 241 + P +S PG GL GP+G G + TP Sbjct: 2655 AGHKGEMGEPGVPG--------QSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTP 2706 Query: 242 GPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD-GPPAVSSQPSGGRSLG 300 G +G F PG G PP PPG + P Q +G+ GPP G R +G Sbjct: 2707 G--IGGF---PGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPP-------GERVVG 2754 Query: 301 EEGPPTRGASPPTPPVSIKSERLSPAPGGP 330 G P GA + E+ P P GP Sbjct: 2755 APGVP--GAP------GERGEQGRPGPAGP 2776 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 64.3 bits (155), Expect = 2e-10 Identities = 83/251 (33%), Positives = 94/251 (37%), Gaps = 53/251 (21%) Query: 94 GLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCD 153 GL G EP E E PGE+ + G GG P LP P P P G PPG Sbjct: 334 GLLGDRGEPGEDGE-PGEQGPQ--GLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGV- 389 Query: 154 PSGLGEALPAQSRPSPFRPAA---PKA-GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRS 209 P G+ P+ P P P A GPPG P P T + P G++ Sbjct: 390 PGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPG-FTGRPGGPGVAGALGQKG 448 Query: 210 DL--PG--GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPP 265 DL PG GL GP G GLQ P A P P G LPG E GL PP Sbjct: 449 DLGLPGQPGLRGPSG--------IPGLQGP---AGPIGPQG----LPGLKGEPGLPGPPG 493 Query: 266 PPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSP 325 +P T P P G P ++ P GPP PP P Sbjct: 494 EGRAGEPGTAGPTGPPGVPGSPGITGPP---------GPP----GPPGP----------- 529 Query: 326 APGGPGDFPKT 336 PG PG F +T Sbjct: 530 -PGAPGAFDET 539 Score = 63.5 bits (153), Expect = 3e-10 Identities = 83/258 (32%), Positives = 96/258 (37%), Gaps = 45/258 (17%) Query: 92 GIGLDGPELEPDEG-----PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGA 146 G+G G P +G P PG G G P P + P +P P GA Sbjct: 209 GVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGA 268 Query: 147 L---PPPGCDPSGLGEA--LPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLY 201 + PPG D G+ A LP PS + GPPGL+ P T P L Sbjct: 269 VGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGP-------TGYGMPGLP 321 Query: 202 LPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPG--GPP--- 256 P R GL G RG G Q P P P L LPG GPP Sbjct: 322 GPKGDRGPAGVPGLLGDRG--EPGEDGEPGEQGPQGLGGP-PGLPGSAGLPGRRGPPGPK 378 Query: 257 -EYGLGDPPPPPGLLQPPTLAPWQPSRGD-GPPAVSSQPSGGRSLGEEGPPTRGASPPTP 314 E G G PP PG+ RGD GP ++ +P GE G P GA P Sbjct: 379 GEAGPGGPPGVPGI------------RGDQGPSGLAGKPG---VPGERGLP--GAHGPPG 421 Query: 315 PVSIKSE-RLSPAPGGPG 331 P K E + PGGPG Sbjct: 422 PTGPKGEPGFTGRPGGPG 439 Score = 62.4 bits (150), Expect = 6e-10 Identities = 82/279 (29%), Positives = 93/279 (33%), Gaps = 57/279 (20%) Query: 116 LAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAP 175 L GE G P P PR P P P PG GL P + P F Sbjct: 75 LKGEPGPPGKPGPRGPPGPPGFPG---------KPGMGKPGL-HGQPGPAGPPGFSRMG- 123 Query: 176 KAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNP 235 KAGPPGL + P + P + R P GL GP G + G+ P Sbjct: 124 KAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGP 183 Query: 236 CS-------TATPGPP----------LGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPW 278 PGPP +G P LPG P G G P PPGL P Sbjct: 184 PGFQGEPGPQGEPGPPGDRGLKGDNGVGQ-PGLPGAP---GQGGAPGPPGLPGP------ 233 Query: 279 QPSRGDGPPAVSSQPSGGRSLGEEGPP----TRG----ASPPTPP----VSIKSERLSPA 326 G G P + P GE GPP RG P PP V + P Sbjct: 234 ---AGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPG 290 Query: 327 PGGP----GDFPKTFPYPLLLARSLAEPLRPGPALRRLP 361 P GP G+ P L+ P PGP R P Sbjct: 291 PQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGP 329 Score = 38.9 bits (89), Expect = 0.007 Identities = 75/238 (31%), Positives = 86/238 (36%), Gaps = 34/238 (14%) Query: 151 GCDP---SGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGR 207 GC P SG G A P + K GP G P + P PL LP + + Sbjct: 21 GCGPRASSGGGAGGAAGYAPVKYIQPMQK-GPVG--PPFREGKGQYLEMPLPL-LPMDLK 76 Query: 208 RSDLPGGLAGPRGGLNTSRSLYS-GLQNPCSTATPGP--PLGSFPFLPGGPPEY-GLGDP 263 P G GPRG G+ P PGP P G GPP G P Sbjct: 77 GEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGP 136 Query: 264 PPPPGLLQPPTLAPWQPSRG-DGPPAVSSQPSG----GR--SLGEEGPPTRGASP----- 311 P PGL P + Q RG GPP + PSG G+ + G GPP P Sbjct: 137 PGQPGLRGEPGIRGDQGLRGPPGPPGLPG-PSGITIPGKPGAQGVPGPPGFQGEPGPQGE 195 Query: 312 PTPP--VSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRLPLADGWP 367 P PP +K + PG PG P P P PGPA P DG P Sbjct: 196 PGPPGDRGLKGDNGVGQPGLPG-APGQGGAP-------GPPGLPGPAGLGKPGLDGLP 245 Score = 28.9 bits (63), Expect = 7.7 Identities = 43/146 (29%), Positives = 53/146 (36%), Gaps = 17/146 (11%) Query: 94 GLDGPELEPDEGPEEPGEKFRRLAGEGGD------PALPRPRLYPA--APAMP-SPDVVY 144 G GP+ EP G G+ GD P L P P PA P P + Sbjct: 421 GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP 480 Query: 145 GALPPPGCD-PSGLGEA-LPAQSRPS--PFRPAAP----KAGPPGLVHPLFSPSHLTSKT 196 G PG P G G A P + P+ P P +P GPPG P +P Sbjct: 481 GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETG 540 Query: 197 PPPLYLPTEGRRSDLPGGLAGPRGGL 222 L+LP G + G P+ GL Sbjct: 541 IAGLHLPNGGVEGAVLGKGGKPQFGL 566 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 63.9 bits (154), Expect = 2e-10 Identities = 75/246 (30%), Positives = 92/246 (37%), Gaps = 54/246 (21%) Query: 131 YPAAP-----AMPSPDVVYGALPPPGCDPS-------GLGEALPAQSR---PSPFRPAAP 175 YP P + PSP LPPP + S G G A P +S PS PA P Sbjct: 246 YPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPP 305 Query: 176 KAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNP 235 PPG P F+P PPP+ G+ P + G +P Sbjct: 306 LGSPPG-PKPGFAPPPAPPPPPPPMI------------GIPPPPPPV--------GFGSP 344 Query: 236 CSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSG 295 + P PP SFP P++ PPPPP PTL PP SQP+G Sbjct: 345 GTPPPPSPP--SFP----PHPDFAAPPPPPPPPAADYPTL----------PPPPLSQPTG 388 Query: 296 GRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARS-LAEPLRPG 354 G PP G PP P + P P PK+ + ARS L +R G Sbjct: 389 GAPPPPPPPPPPG-PPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQG 447 Query: 355 PALRRL 360 LRR+ Sbjct: 448 FQLRRV 453 Score = 48.5 bits (114), Expect = 9e-06 Identities = 56/200 (28%), Positives = 67/200 (33%), Gaps = 64/200 (32%) Query: 90 RRGIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPP 149 +RG GL GP+ P P A G P P+P P P P + G PP Sbjct: 281 QRGSGLAGPKRSSVVSPSHPPP-----APPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPP 335 Query: 150 PGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRS 209 P P G G P P +P + PP HP F + PPP P + Sbjct: 336 P--PPVGFGS-------PGTPPPPSPPSFPP---HPDF------AAPPPPPPPPAADYPT 377 Query: 210 DLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGL 269 P L+ P GG A P PP PPPPPG Sbjct: 378 LPPPPLSQPTGG-----------------APPPPP------------------PPPPPGP 402 Query: 270 LQPPTLAPWQPSRGDGPPAV 289 PP + DG PA+ Sbjct: 403 PPPPF------TGADGQPAI 416 Score = 37.4 bits (85), Expect = 0.022 Identities = 35/102 (34%), Positives = 37/102 (36%), Gaps = 11/102 (10%) Query: 118 GEGGDPALPRPRLYP-----AAPAMPSPDVV--YGALPPPGCDPSGLGEALPAQSRPSPF 170 G G P P P +P AAP P P Y LPPP G P P P Sbjct: 342 GSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG 401 Query: 171 RPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLP-TEGRRSDL 211 P P G G P P L+ T P LP RSDL Sbjct: 402 PPPPPFTGADG--QPAIPPP-LSDTTKPKSSLPAVSDARSDL 440 >gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] Length = 464 Score = 63.9 bits (154), Expect = 2e-10 Identities = 70/234 (29%), Positives = 87/234 (37%), Gaps = 35/234 (14%) Query: 126 PRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSP-FRPAAPKAGPPGL-V 183 PRP L + P P + +PP G PSG P P+P P AP PP V Sbjct: 243 PRPPLPESLPPPPPGGLPLPPMPPTGPAPSG-PPGPPQLPPPAPGVHPPAPVVHPPASGV 301 Query: 184 HP----LFSPSHLTSKTPPPLYLPTEGRRSDLPG------GLAGPRGGLNTSRSLYSGLQ 233 HP + P+ P ++ PT G PG G+ P G++ G+ Sbjct: 302 HPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPA---PGVH 358 Query: 234 NPCSTATPGPPLGSFPFLPGGPPEYGLGDP------PPPPGL-LQPPTLAPWQPSRGDGP 286 P P P G P PG P P PP PG+ Q P + P P Sbjct: 359 PPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSA 418 Query: 287 PAVSSQPSGGRSLGEEGPPTRGASPPTP-PVSIKSERLSPAPG-GPGDFPKTFP 338 P V QP G P G PPTP P ++ P P GPG+ P P Sbjct: 419 PGVHPQPPGVH------PSNPGVHPPTPMPPMLR----PPLPSEGPGNIPPPPP 462 Score = 52.4 bits (124), Expect = 6e-07 Identities = 74/259 (28%), Positives = 92/259 (35%), Gaps = 45/259 (17%) Query: 132 PAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSH 191 PA P++P+ PPP L LP RP P + P P GL P P+ Sbjct: 218 PAPPSLPAGPPGVKRPPPP------LMNGLPP--RP-PLPESLPPPPPGGLPLPPMPPTG 268 Query: 192 LTSKTPP-PLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPF 250 PP P LP P + P SG+ P P P G P Sbjct: 269 PAPSGPPGPPQLPPPAPGVHPPAPVVHPPA---------SGVHPPAPGVHPPAP-GVHPP 318 Query: 251 LPG-GPPEYGLGDP-----PPPPGLLQPPTLAPWQPSRGDGPPA--VSSQPSGGRSLGEE 302 PG PP G+ P PP PG+ PP P+ G PPA V PS G Sbjct: 319 APGVHPPTSGVHPPAPGVHPPAPGV-HPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAP 377 Query: 303 G---------PPTRGASPPTPPVSIKSERLSPAPGG-----PGDFPKTFPYPLLLARSLA 348 G P G PP P + ++ + P P G PG P+ P + + Sbjct: 378 GVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQ--PPGVHPSNPGV 435 Query: 349 EPLRPGPALRRLPLADGWP 367 P P P + R PL P Sbjct: 436 HPPTPMPPMLRPPLPSEGP 454 Score = 32.7 bits (73), Expect = 0.53 Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 3/71 (4%) Query: 286 PPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLAR 345 PPA S P+G + PP PP PP+ E L P P G P P + Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPL---PESLPPPPPGGLPLPPMPPTGPAPSG 273 Query: 346 SLAEPLRPGPA 356 P P PA Sbjct: 274 PPGPPQLPPPA 284 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 63.5 bits (153), Expect = 3e-10 Identities = 79/281 (28%), Positives = 95/281 (33%), Gaps = 58/281 (20%) Query: 92 GIGLDGP-ELEPDEGPEEPGEKFRRLAGEGGD-PALPRPRLYPAAPAMPSPDVVYGALPP 149 G G P E P PE P R G G P P PR P PA P+P PP Sbjct: 72 GAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRR-PLVPAGPAPPAAKLRPPP 130 Query: 150 PG----CDPSGLGEALPAQSRPSPFRPAAP--------KAGP------------------ 179 G C P A+ A P+P PA P +AGP Sbjct: 131 EGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA 190 Query: 180 -PGLVHPLFSPSHLTSK---TPPPLYLPTEGRRSDLPGGLAGPRG-GLNTSRSLYSGLQN 234 PG L + L + P + L G + LP L P G + G Sbjct: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLP--LPKPAAPGTVIQTPPFVGAAA 248 Query: 235 PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQ--------PPTLAPWQP------ 280 P + A P PP P P P PPP P L PPT AP P Sbjct: 249 PPAPAAPSPPAAPAPAAPAAAPP----PPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQ 304 Query: 281 SRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSE 321 + G A + P+ G G G P GA+ P +K+E Sbjct: 305 NGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAE 345 Score = 41.2 bits (95), Expect = 0.001 Identities = 43/162 (26%), Positives = 50/162 (30%), Gaps = 50/162 (30%) Query: 172 PAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSG 231 PAAP G PG + PPP G A P GG Sbjct: 75 PAAPAEGAPG-----------AAPEPPP-------------AGRARPGGG---------- 100 Query: 232 LQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGP---PA 288 PGPP P +P GP PPP G P + GP PA Sbjct: 101 -----GPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPA 155 Query: 289 VSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGP 330 ++P+G +L P G P P P PG P Sbjct: 156 GPAKPAGPAALAARAGPGPGPGPGPGP--------GPGPGKP 189 Score = 38.5 bits (88), Expect = 0.010 Identities = 56/216 (25%), Positives = 67/216 (31%), Gaps = 59/216 (27%) Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180 G A P P P+ PA P+P A PPP P+ L +RP P PA P P Sbjct: 245 GAAAPPAPAA-PSPPAAPAPAAPAAAPPPPPPAPATL-------ARP-PGHPAGPPTAAP 295 Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240 + PPP GG AG A Sbjct: 296 AV--------------PPPAAAQN--------GGSAG---------------------AA 312 Query: 241 PGP-PLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSL 299 P P P P G P G P PG+ Q + +S P+ + Sbjct: 313 PAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372 Query: 300 GEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPK 335 GP +GA P V PAPG P PK Sbjct: 373 MVIGPTMQGALPSPAAVP------PPAPGTPTGLPK 402 Score = 34.3 bits (77), Expect = 0.18 Identities = 40/141 (28%), Positives = 48/141 (34%), Gaps = 36/141 (25%) Query: 242 GPPLGSFPFLPGGPPEYGLGD--PPPPPGLLQPPTLAPWQPS----------RGDGPPAV 289 G P G+ P P E G PPP G +P P +P G PPA Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAA 124 Query: 290 SSQPSGGRSLGE-----------EGPPTRGASP--PTPPVSIKSERLSPAPG-GPGDFPK 335 +P S G GP A P P P ++ + R P PG GPG P Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL-AARAGPGPGPGPGPGPG 183 Query: 336 TFPYPLLLARSLAEPLRPGPA 356 P +P PG A Sbjct: 184 PGP---------GKPAGPGAA 195 >gi|19924099 synapsin I isoform Ia [Homo sapiens] Length = 705 Score = 63.5 bits (153), Expect = 3e-10 Identities = 73/245 (29%), Positives = 85/245 (34%), Gaps = 34/245 (13%) Query: 124 ALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLV 183 ALPR R A+P S +G P PG P G + P+ RP P+ GPP Sbjct: 417 ALPRQRQRDASPGRGS----HGQTPSPGALPLGRQTSQQPAGPPAQQRPP-PQGGPP--- 468 Query: 184 HPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSR--SLYSGLQNPCSTATP 241 P + PPL + GL P G R S S Q P S A P Sbjct: 469 ----QPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP 524 Query: 242 ---GPPLGSFPFL--PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGG 296 G S P PG PP P P PP G PP S P GG Sbjct: 525 PTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGG 584 Query: 297 RSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPA 356 + +GPP + P P + + S A P P T P P PGPA Sbjct: 585 QQ--RQGPPQKPPGPAGP-----TRQASQAGPVPRTGPPTTQQP--------RPSGPGPA 629 Query: 357 LRRLP 361 R P Sbjct: 630 GRPKP 634 Score = 29.6 bits (65), Expect = 4.5 Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 5/43 (11%) Query: 263 PPPPPGLLQP-----PTLAPWQPSRGDGPPAVSSQPSGGRSLG 300 PPPPPG P P A + S G P A + PS G S G Sbjct: 31 PPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73 >gi|19924097 synapsin I isoform Ib [Homo sapiens] Length = 669 Score = 63.5 bits (153), Expect = 3e-10 Identities = 73/245 (29%), Positives = 85/245 (34%), Gaps = 34/245 (13%) Query: 124 ALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLV 183 ALPR R A+P S +G P PG P G + P+ RP P+ GPP Sbjct: 417 ALPRQRQRDASPGRGS----HGQTPSPGALPLGRQTSQQPAGPPAQQRPP-PQGGPP--- 468 Query: 184 HPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSR--SLYSGLQNPCSTATP 241 P + PPL + GL P G R S S Q P S A P Sbjct: 469 ----QPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP 524 Query: 242 ---GPPLGSFPFL--PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGG 296 G S P PG PP P P PP G PP S P GG Sbjct: 525 PTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGG 584 Query: 297 RSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPA 356 + +GPP + P P + + S A P P T P P PGPA Sbjct: 585 QQ--RQGPPQKPPGPAGP-----TRQASQAGPVPRTGPPTTQQP--------RPSGPGPA 629 Query: 357 LRRLP 361 R P Sbjct: 630 GRPKP 634 Score = 37.0 bits (84), Expect = 0.028 Identities = 49/202 (24%), Positives = 64/202 (31%), Gaps = 29/202 (14%) Query: 101 EPDEGPEEPGEKFRR---------LAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151 +P GP+ G ++ L+G G P P+ P+ + P A P G Sbjct: 469 QPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQG 528 Query: 152 ----CDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHP--LFSPSHLTSKTPPPLYLPTE 205 P G P +RP +AGPP + P+ + PP + Sbjct: 529 QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQ 588 Query: 206 GRRSDLPG--------GLAGP---RGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGG 254 G PG AGP G T + SG P P P L P Sbjct: 589 GPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSG---PGPAGRPKPQLAQKPSQDVP 645 Query: 255 PPEYGLGDPPPPPGLLQPPTLA 276 PP PP P L P A Sbjct: 646 PPATAAAGGPPHPQLKASPAQA 667 Score = 29.6 bits (65), Expect = 4.5 Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 5/43 (11%) Query: 263 PPPPPGLLQP-----PTLAPWQPSRGDGPPAVSSQPSGGRSLG 300 PPPPPG P P A + S G P A + PS G S G Sbjct: 31 PPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73 >gi|14249150 single stranded DNA binding protein 4 isoform a [Homo sapiens] Length = 385 Score = 63.2 bits (152), Expect = 4e-10 Identities = 77/248 (31%), Positives = 95/248 (38%), Gaps = 55/248 (22%) Query: 133 AAPAMPSPDVVYGALPPPGCDPSGLGEAL----PAQSRPSPFRPAAPKAGPPGLVHPLFS 188 +A A PSP V G++ P +G A P S+PSP P AP GP G P S Sbjct: 94 SAAAAPSP--VMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHG--QPFMS 149 Query: 189 PSH-------LTSKTPPPLYLPTEGRRSDLPGGLA-GPRGGLNTSRSLYSGLQNPCSTAT 240 P L + PP LP G + LPG + PR + S + P T Sbjct: 150 PRFPGGPRPTLRMPSQPPAGLP--GSQPLLPGAMEPSPRAQGHPS------MGGPMQRVT 201 Query: 241 PGPPLGSFPFLPGGPPEYGLGDPPPP-----PGL----LQPPTLAPWQPSRGDGPPAVSS 291 P + S GP YG G PPP PGL + P PW G+ P SS Sbjct: 202 PPRGMASV-----GPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSS 256 Query: 292 QPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPK---TFPYPLLLARSLA 348 P GPP G P TP + P+PG + + T P+ A Sbjct: 257 SPG-----SYTGPPGGGGPPGTP--------IMPSPGDSTNSSENMYTIMNPIGQGAGRA 303 Query: 349 E-PLRPGP 355 PL PGP Sbjct: 304 NFPLGPGP 311 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 62.8 bits (151), Expect = 5e-10 Identities = 66/190 (34%), Positives = 74/190 (38%), Gaps = 38/190 (20%) Query: 176 KAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNP 235 KAGPPG P + P +P G R P G GP P Sbjct: 185 KAGPPGGSSRAAFPQGGRGRGRFPGAVPG-GDRFPGPAGPGGPPPPF------------P 231 Query: 236 CSTATPGPPLGSFPFLPGGPPEYGLGDP-PPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294 P PPLG P GPP G P PPPPG + PP LA P+RGD PP P Sbjct: 232 AGQTPPRPPLG-----PPGPP----GPPGPPPPGQVLPPPLAG-PPNRGDRPPPPVLFP- 280 Query: 295 GGRSLGEEGPPTRGASPPTPPVSIKSERLSPA--------PGGPGDFPKTFPYPLLLARS 346 G+ G+ P G PP PP + P P PG FP P PL + Sbjct: 281 -GQPFGQ---PPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT 336 Query: 347 LAEPLR-PGP 355 LA P PGP Sbjct: 337 LAPPPHLPGP 346 Score = 60.1 bits (144), Expect = 3e-09 Identities = 77/252 (30%), Positives = 90/252 (35%), Gaps = 58/252 (23%) Query: 101 EPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEA 160 E GP PG R +GG P P P P G PPP P+G Sbjct: 183 EGKAGP--PGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGP-AGPGGPPPPF--PAGQTPP 237 Query: 161 LPAQSRPSPFRPAAPKAGPPGLV--HPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGP 218 P P P P P PPG V PL P + + PPP+ P + P Sbjct: 238 RPPLGPPGP--PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ------------P 283 Query: 219 RGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPG-----GPPEYGLGDPPPP------- 266 G Q P PGPP P +PG GPP G PPPP Sbjct: 284 FG------------QPPLGPLPPGPP----PPVPGYGPPPGPPPPQQGPPPPPGPFPPRP 327 Query: 267 PGLL-QPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPT----PPVSIKSE 321 PG L P TLAP P GPP + P+ + PPT P + PP + Sbjct: 328 PGPLGPPLTLAP--PPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYG 385 Query: 322 RLSPAPGGPGDF 333 R P P GD+ Sbjct: 386 R--PPPYDRGDY 395 Score = 47.4 bits (111), Expect = 2e-05 Identities = 63/194 (32%), Positives = 71/194 (36%), Gaps = 42/194 (21%) Query: 86 ETLKRRGIGLDGPELEPDEGPEEPGEKFRR-LAG---EGGDPALP---------RPRLYP 132 +T R +G GP P GP PG+ LAG G P P +P L P Sbjct: 234 QTPPRPPLGPPGPPGPP--GPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291 Query: 133 AAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHL 192 P P P YG PPPG P G P P PF P P GP G L P HL Sbjct: 292 LPPGPPPPVPGYG--PPPGPPPPQQGPPPP----PGPFPPRPP--GPLGPPLTLAPPPHL 343 Query: 193 TSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLP 252 PPP P + P P SG+ P S + PP + Sbjct: 344 PG--PPPGAPPPAPHVN--PAFFPPPTN---------SGM--PTSDSRGPPPTDPY---- 384 Query: 253 GGPPEYGLGDPPPP 266 G PP Y GD PP Sbjct: 385 GRPPPYDRGDYGPP 398 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.140 0.441 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,336,058 Number of Sequences: 37866 Number of extensions: 1958176 Number of successful extensions: 18513 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 310 Number of HSP's successfully gapped in prelim test: 1624 Number of HSP's that attempted gapping in prelim test: 8344 Number of HSP's gapped (non-prelim): 6759 length of query: 368 length of database: 18,247,518 effective HSP length: 104 effective length of query: 264 effective length of database: 14,309,454 effective search space: 3777695856 effective search space used: 3777695856 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.