Guide to the Human Genome
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Search of human proteins with 224809412

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224809412 myocyte enhancer factor 2B isoform a [Homo
sapiens]
         (368 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224809412 myocyte enhancer factor 2B isoform a [Homo sapiens]      771   0.0  
gi|5174543 myocyte enhancer factor 2B isoform b [Homo sapiens]        540   e-154
gi|19923215 myocyte enhancer factor 2C isoform 1 [Homo sapiens]       191   9e-49
gi|196114945 myocyte enhancer factor 2C isoform 2 [Homo sapiens]      184   1e-46
gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]      181   7e-46
gi|195972799 myocyte enhancer factor 2A isoform 1 [Homo sapiens]      180   2e-45
gi|5174545 myocyte enhancer factor 2D [Homo sapiens]                  180   2e-45
gi|146134388 YLP motif containing 1 [Homo sapiens]                     74   2e-13
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                71   2e-12
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          69   5e-12
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          69   5e-12
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          69   5e-12
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    69   9e-12
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    68   1e-11
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    67   3e-11
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    66   6e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is...    66   6e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni...    66   6e-11
gi|160707881 formin 2 [Homo sapiens]                                   65   1e-10
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        65   1e-10
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        65   1e-10
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          64   2e-10
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                64   2e-10
gi|11386183 WAS protein family, member 2 [Homo sapiens]                64   2e-10
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               64   2e-10
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    64   3e-10
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       64   3e-10
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       64   3e-10
gi|14249150 single stranded DNA binding protein 4 isoform a [Hom...    63   4e-10
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    63   5e-10

>gi|224809412 myocyte enhancer factor 2B isoform a [Homo sapiens]
          Length = 368

 Score =  771 bits (1992), Expect = 0.0
 Identities = 368/368 (100%), Positives = 368/368 (100%)

Query: 1   MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60
           MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST
Sbjct: 1   MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60

Query: 61  DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG 120
           DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG
Sbjct: 61  DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG 120

Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180
           GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP
Sbjct: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180

Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240
           GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT
Sbjct: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240

Query: 241 PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLG 300
           PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLG
Sbjct: 241 PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLG 300

Query: 301 EEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRL 360
           EEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRL
Sbjct: 301 EEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRL 360

Query: 361 PLADGWPR 368
           PLADGWPR
Sbjct: 361 PLADGWPR 368


>gi|5174543 myocyte enhancer factor 2B isoform b [Homo sapiens]
          Length = 365

 Score =  540 bits (1392), Expect = e-154
 Identities = 281/350 (80%), Positives = 282/350 (80%), Gaps = 18/350 (5%)

Query: 1   MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60
           MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST
Sbjct: 1   MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60

Query: 61  DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG 120
           DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG
Sbjct: 61  DMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEG 120

Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180
           GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP
Sbjct: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180

Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240
           GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT
Sbjct: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240

Query: 241 PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPS------RGDGPPAV----- 289
           PGPPLGSFPFLPGGPP          P    PP   P   S      R  G PA      
Sbjct: 241 PGPPLGSFPFLPGGPPVGAEAWARRVPQPAAPPRRPPQSASSLSASLRPPGAPATFLRPS 300

Query: 290 ---SSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKT 336
               S P   +SL   GPP  G   PT        R SP    P   P T
Sbjct: 301 PIPCSSPGPWQSLCGLGPPCAGCPWPTAGPG----RRSPGGTSPERSPGT 346


>gi|19923215 myocyte enhancer factor 2C isoform 1 [Homo sapiens]
          Length = 473

 Score =  191 bits (485), Expect = 9e-49
 Identities = 130/323 (40%), Positives = 174/323 (53%), Gaps = 27/323 (8%)

Query: 1   MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60
           MGRKKIQI+RI+D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNS N+LFQYAST
Sbjct: 1   MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYAST 60

Query: 61  DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEG---PEEPGEKFRRL 116
           DMD+VLLKYTEY+EPHESRTN+DI+ETL+++G+ G D P+ + D+      E  +K+R++
Sbjct: 61  DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKI 120

Query: 117 AGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPS-PFRPAAP 175
             E  D  + R RL               A+PPP  +   +  ++P  S  S  +     
Sbjct: 121 -NEDIDLMISRQRLC--------------AVPPPNFE---MPVSIPVSSHNSLVYSNPVS 162

Query: 176 KAGPPGLVHPLFSPSHLTSKTPPPL--YLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQ 233
             G P L+ PL  PS   +   P +    P+ G    L GG      G +      +   
Sbjct: 163 SLGNPNLL-PLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRN 221

Query: 234 NPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQP 293
           +P    +PG    +       P   G+ +  P   +L PP      PS  +    + +Q 
Sbjct: 222 SPGLLVSPGNLNKNMQAKSPPPMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVDLLLNQR 281

Query: 294 -SGGRSLGEEGPPTRGASPPTPP 315
            +  +S      P    + PT P
Sbjct: 282 INNSQSAQSLATPVVSVATPTLP 304


>gi|196114945 myocyte enhancer factor 2C isoform 2 [Homo sapiens]
          Length = 463

 Score =  184 bits (467), Expect = 1e-46
 Identities = 149/404 (36%), Positives = 194/404 (48%), Gaps = 71/404 (17%)

Query: 1   MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60
           MGRKKIQI+RI+D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNS N+LFQYAST
Sbjct: 1   MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYAST 60

Query: 61  DMDRVLLKYTEYSEPHESRTNTDILETL-KRRGIGLDGPE------LEP--DEGPEEPGE 111
           DMD+VLLKYTEY+EPHESRTN+DI+E L K+   G + P+      L P  +E  ++  E
Sbjct: 61  DMDKVLLKYTEYNEPHESRTNSDIVEALNKKENKGCESPDPDSSYALTPRTEEKYKKINE 120

Query: 112 KFRRLAGEGGDPALP----------------------------RPRLYPAA-PAMP---- 138
           +F  +      PA+P                             P L P A P++     
Sbjct: 121 EFDNMIKSHKIPAVPPPNFEMPVSIPVSSHNSLVYSNPVSSLGNPNLLPLAHPSLQRNSM 180

Query: 139 SPDVVYGALPPPGCDPSGL--GEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKT 196
           SP V +   PP   +  GL  G+        +      P+  P  LV P     ++ +K+
Sbjct: 181 SPGVTH--RPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRNSPGLLVSPGNLNKNMQAKS 238

Query: 197 PPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSF--PFLP-- 252
           PPP+ L    R+ DL   +  P G  NT  S+   + N  S  +   P+ S   P LP  
Sbjct: 239 PPPMNLGMNNRKPDL--RVLIPPGSKNTMPSVNQRINNSQSAQSLATPVVSVATPTLPGQ 296

Query: 253 --GGPP---------EYGLGDPP-------PPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294
             GG P         EY L                L   ++  WQ       P  +    
Sbjct: 297 GMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQL 356

Query: 295 GGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFP 338
           G  +       +  + P T  ++IKSE +SP P      P  +P
Sbjct: 357 GACTSTHLSQSSNLSLPSTQSLNIKSEPVSP-PRDRTTTPSRYP 399


>gi|195972801 myocyte enhancer factor 2A isoform 2 [Homo sapiens]
          Length = 497

 Score =  181 bits (460), Expect = 7e-46
 Identities = 123/293 (41%), Positives = 161/293 (54%), Gaps = 29/293 (9%)

Query: 1   MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60
           MGRKKIQI+RI+D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNS+N+LFQYAST
Sbjct: 1   MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 60

Query: 61  DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEGPEEP--GEKFRRLA 117
           DMD+VLLKYTEY+EPHESRTN+DI+ETL+++G+ G + P+ + D     P   ++F +L 
Sbjct: 61  DMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDAD-DYFEHSPLSEDRFSKL- 118

Query: 118 GEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKA 177
            E  D    R       P +P P     ++  P   P+ L    P  S  SP   A+   
Sbjct: 119 NEDSDFIFKR-----GPPGLP-PQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTL 172

Query: 178 GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL--------PGGL-AGPRG-GLNTSRS 227
               ++ P  +  H       P   P+ G    +        P G  + P G G   SR+
Sbjct: 173 TDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRA 232

Query: 228 L--------YSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQP 272
                     + L     T +P PP G    +    P+  +  PP   G++ P
Sbjct: 233 SPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPP 285


>gi|195972799 myocyte enhancer factor 2A isoform 1 [Homo sapiens]
          Length = 499

 Score =  180 bits (456), Expect = 2e-45
 Identities = 123/294 (41%), Positives = 159/294 (54%), Gaps = 29/294 (9%)

Query: 1   MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60
           MGRKKIQI+RI+D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNS+N+LFQYAST
Sbjct: 1   MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST 60

Query: 61  DMDRVLLKYTEYSEPHESRTNTDILETL-KRRGIGLDGPELEPDEG---PEEPGEKFRRL 116
           DMD+VLLKYTEY+EPHESRTN+DI+E L K+   G D P  +PD          EK++++
Sbjct: 61  DMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSP--DPDTSYVLTPHTEEKYKKI 118

Query: 117 AGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPK 176
             E  +      R +  AP +P P     ++  P   P+ L    P  S  SP   A+  
Sbjct: 119 NEEFDN----MMRNHKIAPGLP-PQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASST 173

Query: 177 AGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL--------PGGL-AGPRG-GLNTSR 226
                ++ P  +  H       P   P+ G    +        P G  + P G G   SR
Sbjct: 174 LTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSR 233

Query: 227 SL--------YSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQP 272
           +          + L     T +P PP G    +    P+  +  PP   G++ P
Sbjct: 234 ASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPP 287


>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
          Length = 521

 Score =  180 bits (456), Expect = 2e-45
 Identities = 171/468 (36%), Positives = 204/468 (43%), Gaps = 130/468 (27%)

Query: 1   MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYAST 60
           MGRKKIQI RI D+RNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFN +N+LFQYAST
Sbjct: 1   MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST 60

Query: 61  DMDRVLLKYTEYSEPHESRTNTDILETLKRRGI-GLDGPELEPDEGPEEP---GEKFRRL 116
           DMD+VLLKYTEY+EPHESRTN DI+ETL+++G  G D PE + ++  E+     +K+RR 
Sbjct: 61  DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRR- 119

Query: 117 AGEGGDPALPRPRLYPAAPAMPSPDVV-------------YGALPPPG------CDPSGL 157
           A E  D    R      AP    P  V              G+L  P        DP  L
Sbjct: 120 ASEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLL 179

Query: 158 GEALPAQSRPS-----PFRPAAPKA-------------------------GPPGLVHPLF 187
               PA  R S     P RPA+  A                           PGL+ P+ 
Sbjct: 180 SPQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLL-PVA 238

Query: 188 SPSHLT----SKTPPP----LYLPTEGRRSDLPGGLAGPRGG-----------------L 222
           + + L     +K+PPP      L    R+ DL    +    G                 L
Sbjct: 239 NGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRL 298

Query: 223 NTSRSLYSGLQNPCSTATP-----GPPLGSFPFL--------------------PGG--- 254
             S+S +S      S ATP     G P  S P                      PGG   
Sbjct: 299 GVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSL 358

Query: 255 ----------PPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ--PSGGRSLGEE 302
                      P+      PP     QP    P QP +   PP   S   P    +L   
Sbjct: 359 GNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPG 418

Query: 303 GP-PTRGAS---PPTPPVSIKSERL------SPAPGGPGDFPKTFPYP 340
            P P  GA+      P +SIKSE +      SPAP  P  FP   P P
Sbjct: 419 SPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEP 466


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 73/254 (28%), Positives = 101/254 (39%), Gaps = 53/254 (20%)

Query: 123 PALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGL 182
           P +P P L P+ P    P  +   +PPPG  P  +  +LP    P    P+   AGPP  
Sbjct: 531 PTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPP-- 588

Query: 183 VHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPG 242
             P+  P  L+S  PPP+  P                               P  ++T  
Sbjct: 589 --PVLPPPSLSSAGPPPVLPP-------------------------------PSLSSTAP 615

Query: 243 PPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ----PSGGRS 298
           PP+   P L    P  G+    PPPG+   P   P Q +    PPA SSQ    P   R 
Sbjct: 616 PPVMPLPPLSSATPPPGI----PPPGV---PQGIPPQLTAAPVPPASSSQSSQVPEKPRP 668

Query: 299 LGEEGPPTRGASPPT---PPVSI--KSERL-SPAPGGPGDFP-KTFPYPLLLARSLAEPL 351
                P + G++PPT   PP+     SE++ S AP      P  +F     L  S A P 
Sbjct: 669 ALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPS 728

Query: 352 RPGPALRRLPLADG 365
           +P  A++ +P+  G
Sbjct: 729 QPITAVKDMPVRSG 742



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 77/293 (26%), Positives = 107/293 (36%), Gaps = 50/293 (17%)

Query: 116 LAGEGGDPALPRPRLYPAA--PAMPSPDV-------------VYGALPPPGCDPSGLGEA 160
           L+  G  P LP P L  A   P +P P +             +  A PPPG  P G+ + 
Sbjct: 582 LSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQG 641

Query: 161 LPAQSRPSPFRPAAPKAGP--PGLVHPLFSPSHLT-SKTPPPLYLPTEGRRSDLPGGLAG 217
           +P Q   +P  PA+       P    P   P+ ++    PP  Y P    +S  P     
Sbjct: 642 IPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPP--LQSAGPSEQVN 699

Query: 218 PRGGLNTSRSLYSGLQNPC----STATPGPPLGSFPFLP---GG----PPEYGLGDPPPP 266
            +  L+ S   YS   +      S+A P  P+ +   +P   GG    PP     + P  
Sbjct: 700 SKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRG 759

Query: 267 PGLLQPPTL----APWQPSRGDGPPAVSSQPSGGRSLGE----EGPPTRGASPPTPPVS- 317
           P    P       +  +  R  GP    ++P G R   E    EG  ++    P  P S 
Sbjct: 760 PRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQ 819

Query: 318 ---IKSERLSPAPGGP---GDFPKTFPYPLLLARSLAEPLRPGPALRRLPLAD 364
                S  LSP   GP   G  P          +S AEPL    +  + PLAD
Sbjct: 820 FYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPL----SGNKEPLAD 868



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 39/123 (31%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 241 PGPPLGSFPFLPGGPPEYGLGD--PPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ---PSG 295
           P PPL   P +PGG    G GD  PPPPP    P     +Q  +      +  Q   P G
Sbjct: 82  PPPPLPPPPVMPGG----GYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137

Query: 296 GRSLGEEGPPTRGASPPTPPVSI--KSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRP 353
              +  E PP    SPP PP S    S+   P P  P  +     YP   ++    P +P
Sbjct: 138 LVPMELESPP---ESPPVPPGSYMPPSQSYMPPPQPPPSY-----YPPTSSQPYLPPAQP 189

Query: 354 GPA 356
            P+
Sbjct: 190 SPS 192



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 65/249 (26%), Positives = 79/249 (31%), Gaps = 59/249 (23%)

Query: 131 YPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGP----------- 179
           Y  +   P P V     PPP   P  L EA P     S   PAAP +             
Sbjct: 8   YGGSSHYPPPPV-----PPP--PPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQ 60

Query: 180 --------PGLVHPLFSPSHLTSKT-PPPLYLPTEGRRSDLPGGLA-----GPRGGLNTS 225
                      +  +  P HL     PPP  +P  G     P         GP       
Sbjct: 61  LQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ 120

Query: 226 RSLYSGLQNPCSTATPG-------PPLGSFPFLPGG--PPEYGLGDPPPPPGLLQPPT-- 274
           +     + +      PG        P  S P  PG   PP      PP PP    PPT  
Sbjct: 121 QQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS 180

Query: 275 ---LAPWQPSRGDGP---------PAVSSQPSGGRSL---GEEGPPTRGASPPTPPVS-I 318
              L P QPS    P         P+ SS  S  +S     +   P+  ASP  P     
Sbjct: 181 QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS 240

Query: 319 KSERLSPAP 327
           KS+ L+P P
Sbjct: 241 KSQLLAPPP 249



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 32/107 (29%), Positives = 41/107 (38%), Gaps = 18/107 (16%)

Query: 255 PPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTP 314
           PP       PPP   + PP L P  P     P   ++ P  G       PP     PP+ 
Sbjct: 518 PPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMP-----PP---VMPPSL 569

Query: 315 PVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAE----PLRPGPAL 357
           P S+      P PG P       P P+L   SL+     P+ P P+L
Sbjct: 570 PTSV------PPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSL 610



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 57/213 (26%), Positives = 74/213 (34%), Gaps = 42/213 (19%)

Query: 125 LPRPRLYPAAPAMPSPDVVYGAL-PPPGCDPSGLGEALPAQSRPSPFRPAA--PKAGPPG 181
           LP P L P  P MP     YG   PPP   P   G AL  Q +           + GPPG
Sbjct: 81  LPPPPL-PPPPVMPGGG--YGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137

Query: 182 LVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATP 241
           LV         +   PP  Y+P    +S +P     P        S Y            
Sbjct: 138 LVPMELESPPESPPVPPGSYMPPS--QSYMPPPQPPP--------SYY------------ 175

Query: 242 GPPLGSFPFLPGGPPEYGLGDPPPPPGLLQP-PTLAPWQPSRGD----------GPPAVS 290
            PP  S P+LP  P +      PP    L P P+ +    S                A  
Sbjct: 176 -PPTSSQPYLP--PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP 232

Query: 291 SQPSGGRSLGEEGPPTRGASPPTPPVSIKSERL 323
           S+PS G S  +   P   ++PP    +++ E L
Sbjct: 233 SRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPL 265



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 5/38 (13%)

Query: 132  PAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSP 169
            P+AP +P P V + ++PPPG  P G    +P  S+P P
Sbjct: 1603 PSAPVLPPPPV-HSSIPPPGPVPMG----MPPMSKPPP 1635



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 24/65 (36%), Positives = 25/65 (38%), Gaps = 6/65 (9%)

Query: 252  PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASP 311
            PG  P  G   PPPP G        P    R   PPA SS P     +    PP     P
Sbjct: 1503 PGMYPPPGSYRPPPPMG------KPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLP 1556

Query: 312  PTPPV 316
            P PPV
Sbjct: 1557 PPPPV 1561



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 38/170 (22%), Positives = 56/170 (32%), Gaps = 31/170 (18%)

Query: 125 LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALP------AQSRPSPFRPAAPKAG 178
           LP  +  P+ P+         A PPP   P              A+++ +  + AAP+  
Sbjct: 225 LPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPD 284

Query: 179 P----PGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQN 234
           P    P      +   HL S          +  +  LPG   GP    +T   +   +  
Sbjct: 285 PSTMTPQEQQQYWYRQHLLSLQ--------QRTKVHLPGHKKGPVVAKDTPEPVKEEVTV 336

Query: 235 PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD 284
           P ++  P  P    P             P PPP    PP L P +P   D
Sbjct: 337 PATSQVPESPSSEEP-------------PLPPPNEEVPPPLPPEEPQSED 373



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 44/187 (23%), Positives = 66/187 (35%), Gaps = 38/187 (20%)

Query: 108  EPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRP 167
            E  E+ +++   G +P +    L P    + +     G  PPPG                
Sbjct: 1468 EQKEQLQKMKDFGSEPQMA-DHLPPQESRLQNTSSRPGMYPPPGS--------------- 1511

Query: 168  SPFRPAAPKAGPPG-LVHPLFSPSHLT-SKTPPPLYLPTEGRRSDLP----------GGL 215
              +RP  P   PPG +V P   P+  +   T PP+ +P       LP            +
Sbjct: 1512 --YRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAV 1569

Query: 216  AGPRGGLNTSRSLY-----SGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLL 270
               R   ++   L+      GL +   + T   P  S P LP  PP +    PP P  + 
Sbjct: 1570 EQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIP--SAPVLP-PPPVHSSIPPPGPVPMG 1626

Query: 271  QPPTLAP 277
             PP   P
Sbjct: 1627 MPPMSKP 1633



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 22/133 (16%)

Query: 231  GLQNPCSTATPGPPLGSFP---FLPGGPPEYG----------LGDPPPPPGLLQPPTLAP 277
            G+  P  +  P PP+G  P     P  PP             +  PPPPP L  PP +  
Sbjct: 1504 GMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIK 1563

Query: 278  WQPS-----RGDGPPAV----SSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPG 328
             Q S     R D         ++   G  S  +       ++P  PP  + S    P P 
Sbjct: 1564 PQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPV 1623

Query: 329  GPGDFPKTFPYPL 341
              G  P + P P+
Sbjct: 1624 PMGMPPMSKPPPV 1636


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 67/207 (32%), Positives = 76/207 (36%), Gaps = 24/207 (11%)

Query: 123 PALPRPRLYPAAPAMPSPDVVY-GALPPPGCDPSGLGEALPAQSRPSPFRPAA-----PK 176
           P+ P P +      +P P +   G+ PPP   P  L   +P    P P  P A     P 
Sbjct: 218 PSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPS 277

Query: 177 AGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRS-----DLPGGLAGPRGGLNTSRSLYSG 231
           AG PG  HP    SH      PP  +P  G          P GL  P  G   S      
Sbjct: 278 AGTPGAGHPGHGHSH--PHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGG-QPP 334

Query: 232 LQNPCSTATPGPPLGSFPFLPGGPP---EYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPA 288
            + P     PGPP    P  P GPP     G   P PP G+  PP L P  P    GPP 
Sbjct: 335 PRPPPGMPHPGPPPMGMP--PRGPPFGSPMGHPGPMPPHGMRGPPPLMP--PHGYTGPP- 389

Query: 289 VSSQPSGGRSLGEEGPPTRGASPPTPP 315
               P  G   G   PP     PP PP
Sbjct: 390 --RPPPYGYQRGPLPPPRPTPRPPVPP 414



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 69/231 (29%), Positives = 79/231 (34%), Gaps = 82/231 (35%)

Query: 135 PAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAA-----PKAGPPGLVHPLFSP 189
           P MP P      +PPPG  P G+  A+P    P P  P A     P AG PG  HP    
Sbjct: 235 PGMPPPGSFPPPVPPPGALPPGIPPAMP----PPPMPPGAAGHGPPSAGTPGAGHPGHGH 290

Query: 190 SHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATP--GPPLGS 247
           SH     P P            PGG+  P  G++  +  + G   P     P  GPP GS
Sbjct: 291 SH-----PHPFP----------PGGM--PHPGMSQMQLAHHG---PHGLGHPHAGPP-GS 329

Query: 248 FPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTR 307
                GG P      P PPPG+  P                              GPP  
Sbjct: 330 -----GGQPP-----PRPPPGMPHP------------------------------GPPPM 349

Query: 308 GASPPTPPVSIKSERLSPAPGGPGDFP---KTFPYPLLLARSLAEPLRPGP 355
           G  P  PP        SP  G PG  P      P PL+       P RP P
Sbjct: 350 GMPPRGPPFG------SPM-GHPGPMPPHGMRGPPPLMPPHGYTGPPRPPP 393



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 56/192 (29%), Positives = 64/192 (33%), Gaps = 41/192 (21%)

Query: 123 PALPRPRLYPAA--PAMPSPDVVYGALP--PPGCDPSGLGEALPAQSRPSPFRPAA---- 174
           P +P P   P    PAMP P +  GA    PP     G G      S P PF P      
Sbjct: 245 PPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHP 304

Query: 175 -----------------PKAGPPGL--VHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGL 215
                            P AGPPG     P   P  +    PPP+ +P  G     P G 
Sbjct: 305 GMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGH 364

Query: 216 AGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPP-PPPGLLQPPT 274
            GP            G++ P     P    G     P  PP YG    P PPP     P 
Sbjct: 365 PGPMPP--------HGMRGPPPLMPPHGYTG-----PPRPPPYGYQRGPLPPPRPTPRPP 411

Query: 275 LAPWQPSRGDGP 286
           + P  P RG  P
Sbjct: 412 VPPRGPLRGPLP 423



 Score = 36.2 bits (82), Expect = 0.048
 Identities = 35/114 (30%), Positives = 38/114 (33%), Gaps = 7/114 (6%)

Query: 105 GPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQ 164
           GP   G       G GG P  PRP      P MP P      +PP G  P G     P  
Sbjct: 315 GPHGLGHPHAGPPGSGGQPP-PRP-----PPGMPHPGPPPMGMPPRG-PPFGSPMGHPGP 367

Query: 165 SRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGP 218
             P   R   P   P G   P   P +   + P P   PT        G L GP
Sbjct: 368 MPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGP 421


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 75/224 (33%), Positives = 85/224 (37%), Gaps = 36/224 (16%)

Query: 126 PRPRLYPAAPAM-----PSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180
           PR +  P AP       P P      LP P           P  S PSPF   A    PP
Sbjct: 359 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP-----PHLSGPSPFSMNANLPPPP 413

Query: 181 GLVHPLFSPS--HLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSL----YSGLQN 234
            L  PL S S  H  S  PPPL L  + +   LP   A P G L  S++L     S    
Sbjct: 414 AL-KPLSSLSTHHPPSAHPPPLQLMPQSQ--PLPSSPAQPPG-LTQSQNLPPPPASHPPT 469

Query: 235 PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294
                 P PP    PF+PGGPP      PP  P    PP      P     PP   +  S
Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPA----GPGTSAQPPCSGAAAS 522

Query: 295 GGRSLGEEGPPTRGASPPTPPVSIKSERLSPA--PGGPGDFPKT 336
           GG   G       G+S P P V IK E L  A  P  P   P++
Sbjct: 523 GGSIAG-------GSSCPLPTVQIKEEALDDAEEPESPPPPPRS 559



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 68/257 (26%), Positives = 89/257 (34%), Gaps = 28/257 (10%)

Query: 123 PAL-PRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPG 181
           PAL P+    P  P  PSP      L      PS    A P      P  P + +AGP  
Sbjct: 250 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL- 308

Query: 182 LVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGG----LAGPRGGLN--TSRSLYSGLQNP 235
           L HP           P P  LP +  +   P G     A P   L    S+S     Q P
Sbjct: 309 LQHP---------GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 359

Query: 236 CSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQP--SRGDGPPAVSSQP 293
                P  PL      P  PP   +   P P     PP L+   P     + PP  + +P
Sbjct: 360 REQPLPPAPLAMPHIKP--PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 417

Query: 294 SGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTF---PYPLLLARSLAEP 350
               SL    PP+  A PP   +  +S+ L  +P  P    ++    P P     +    
Sbjct: 418 LS--SLSTHHPPS--AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 473

Query: 351 LRPGPALRRLPLADGWP 367
           + P P   + P   G P
Sbjct: 474 VAPQPPFAQHPFVPGGP 490



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 71/254 (27%), Positives = 89/254 (35%), Gaps = 52/254 (20%)

Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180
           G P LP P   P+A A+P               P G   A  A ++P    P AP     
Sbjct: 203 GTPQLPTPGPTPSATAVP---------------PQGSPTASQAPNQPQ--APTAPVPHTH 245

Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240
               P   P    S  PPP   P       L G    P    +    L+   Q P     
Sbjct: 246 IQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHG--QGP----- 297

Query: 241 PGP-PLGSFPFL--PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGP----PAVSSQ- 292
           PGP  L + P L  PG P  +GL           PP  +  Q   G  P    P  S Q 
Sbjct: 298 PGPHSLQAGPLLQHPGPPQPFGL-----------PPQASQGQAPLGTSPAAAYPHTSLQL 346

Query: 293 PSGGRSLGEEGPPTRGASPPTPPV--SIKSERLSPAPGGPGDFPKTFPYPLLLAR----S 346
           P+   +L  + PP     PP P     IK    +P P  P   P+   +P  L+     S
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA--PQAHKHPPHLSGPSPFS 404

Query: 347 LAEPLRPGPALRRL 360
           +   L P PAL+ L
Sbjct: 405 MNANLPPPPALKPL 418



 Score = 35.4 bits (80), Expect = 0.082
 Identities = 50/162 (30%), Positives = 61/162 (37%), Gaps = 43/162 (26%)

Query: 125 LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVH 184
           +P+ +  P++PA P        LPPP           PA   P+     AP+  PP   H
Sbjct: 437 MPQSQPLPSSPAQPPGLTQSQNLPPP-----------PASHPPTGLHQVAPQ--PPFAQH 483

Query: 185 PLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCS--TATPG 242
           P F P       PPP+  PT    S  P   AGP           +  Q PCS   A+ G
Sbjct: 484 P-FVPG-----GPPPITPPTCPSTSTPP---AGPG----------TSAQPPCSGAAASGG 524

Query: 243 PPLG--SFPFLPGGPPEYGLGD------PPPPPGLLQP-PTL 275
              G  S P       E  L D      PPPPP    P PT+
Sbjct: 525 SIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 566



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 2/54 (3%)

Query: 240 TPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDG--PPAVSS 291
           T GP L  FP+ PG  P   LG PP    +L+ P      P    G  PP +S+
Sbjct: 906 TAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSA 959



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 47/190 (24%), Positives = 71/190 (37%), Gaps = 14/190 (7%)

Query: 75  PHESRTNTDILETLKRRGIGLDGPELEPDEG-PEEPGEK---FRRLAGEGGDPALPRPRL 130
           PH   +    L  L+R  + L GP+L P+   P+    +     R+A    DP L R ++
Sbjct: 807 PHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP-LARLQM 865

Query: 131 YPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAG----PPG-LVHP 185
           +   P       ++  L     DP   G A P      P   A P       PPG L +P
Sbjct: 866 FNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPL-TAGPHLARFPYPPGTLPNP 924

Query: 186 LF-SPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPP 244
           L   P H       P++     R  DLPG +  P    +  +++++        A     
Sbjct: 925 LLGQPPHEHEMLRHPVFGTPYPR--DLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQW 982

Query: 245 LGSFPFLPGG 254
           L   P + GG
Sbjct: 983 LHGHPHMHGG 992



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 39/164 (23%), Positives = 56/164 (34%), Gaps = 11/164 (6%)

Query: 203 PTEGR------RSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPP 256
           P+EG       RS    G + P+     +RS    + +P    +          L   PP
Sbjct: 126 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 185

Query: 257 EYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPV 316
                    P     PP   P  P+ G  P A +  P G  +  +     +  + P P  
Sbjct: 186 ALQAPTGVTPAPSSAPPG-TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 244

Query: 317 SI-KSERLSP-APGGPGDFPKTFPYPLL--LARSLAEPLRPGPA 356
            I ++  L P  P  P   P   P+P L  L  S  +P  P  A
Sbjct: 245 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 288


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 75/224 (33%), Positives = 85/224 (37%), Gaps = 36/224 (16%)

Query: 126  PRPRLYPAAPAM-----PSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180
            PR +  P AP       P P      LP P           P  S PSPF   A    PP
Sbjct: 913  PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP-----PHLSGPSPFSMNANLPPPP 967

Query: 181  GLVHPLFSPS--HLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSL----YSGLQN 234
             L  PL S S  H  S  PPPL L  + +   LP   A P G L  S++L     S    
Sbjct: 968  AL-KPLSSLSTHHPPSAHPPPLQLMPQSQ--PLPSSPAQPPG-LTQSQNLPPPPASHPPT 1023

Query: 235  PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294
                  P PP    PF+PGGPP      PP  P    PP      P     PP   +  S
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPA----GPGTSAQPPCSGAAAS 1076

Query: 295  GGRSLGEEGPPTRGASPPTPPVSIKSERLSPA--PGGPGDFPKT 336
            GG   G       G+S P P V IK E L  A  P  P   P++
Sbjct: 1077 GGSIAG-------GSSCPLPTVQIKEEALDDAEEPESPPPPPRS 1113



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 68/257 (26%), Positives = 89/257 (34%), Gaps = 28/257 (10%)

Query: 123  PAL-PRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPG 181
            PAL P+    P  P  PSP      L      PS    A P      P  P + +AGP  
Sbjct: 804  PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL- 862

Query: 182  LVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGG----LAGPRGGLN--TSRSLYSGLQNP 235
            L HP           P P  LP +  +   P G     A P   L    S+S     Q P
Sbjct: 863  LQHP---------GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913

Query: 236  CSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQP--SRGDGPPAVSSQP 293
                 P  PL      P  PP   +   P P     PP L+   P     + PP  + +P
Sbjct: 914  REQPLPPAPLAMPHIKP--PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 971

Query: 294  SGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTF---PYPLLLARSLAEP 350
                SL    PP+  A PP   +  +S+ L  +P  P    ++    P P     +    
Sbjct: 972  LS--SLSTHHPPS--AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027

Query: 351  LRPGPALRRLPLADGWP 367
            + P P   + P   G P
Sbjct: 1028 VAPQPPFAQHPFVPGGP 1044



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 71/254 (27%), Positives = 89/254 (35%), Gaps = 52/254 (20%)

Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180
           G P LP P   P+A A+P               P G   A  A ++P    P AP     
Sbjct: 757 GTPQLPTPGPTPSATAVP---------------PQGSPTASQAPNQPQ--APTAPVPHTH 799

Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240
               P   P    S  PPP   P       L G    P    +    L+   Q P     
Sbjct: 800 IQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHG--QGP----- 851

Query: 241 PGP-PLGSFPFL--PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGP----PAVSSQ- 292
           PGP  L + P L  PG P  +GL           PP  +  Q   G  P    P  S Q 
Sbjct: 852 PGPHSLQAGPLLQHPGPPQPFGL-----------PPQASQGQAPLGTSPAAAYPHTSLQL 900

Query: 293 PSGGRSLGEEGPPTRGASPPTPPV--SIKSERLSPAPGGPGDFPKTFPYPLLLAR----S 346
           P+   +L  + PP     PP P     IK    +P P  P   P+   +P  L+     S
Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA--PQAHKHPPHLSGPSPFS 958

Query: 347 LAEPLRPGPALRRL 360
           +   L P PAL+ L
Sbjct: 959 MNANLPPPPALKPL 972



 Score = 35.4 bits (80), Expect = 0.082
 Identities = 50/162 (30%), Positives = 61/162 (37%), Gaps = 43/162 (26%)

Query: 125  LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVH 184
            +P+ +  P++PA P        LPPP           PA   P+     AP+  PP   H
Sbjct: 991  MPQSQPLPSSPAQPPGLTQSQNLPPP-----------PASHPPTGLHQVAPQ--PPFAQH 1037

Query: 185  PLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCS--TATPG 242
            P F P       PPP+  PT    S  P   AGP           +  Q PCS   A+ G
Sbjct: 1038 P-FVPG-----GPPPITPPTCPSTSTPP---AGPG----------TSAQPPCSGAAASGG 1078

Query: 243  PPLG--SFPFLPGGPPEYGLGD------PPPPPGLLQP-PTL 275
               G  S P       E  L D      PPPPP    P PT+
Sbjct: 1079 SIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 1120



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 2/54 (3%)

Query: 240  TPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDG--PPAVSS 291
            T GP L  FP+ PG  P   LG PP    +L+ P      P    G  PP +S+
Sbjct: 1460 TAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSA 1513



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 47/190 (24%), Positives = 71/190 (37%), Gaps = 14/190 (7%)

Query: 75   PHESRTNTDILETLKRRGIGLDGPELEPDEG-PEEPGEK---FRRLAGEGGDPALPRPRL 130
            PH   +    L  L+R  + L GP+L P+   P+    +     R+A    DP L R ++
Sbjct: 1361 PHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP-LARLQM 1419

Query: 131  YPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAG----PPG-LVHP 185
            +   P       ++  L     DP   G A P      P   A P       PPG L +P
Sbjct: 1420 FNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPL-TAGPHLARFPYPPGTLPNP 1478

Query: 186  LF-SPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPP 244
            L   P H       P++     R  DLPG +  P    +  +++++        A     
Sbjct: 1479 LLGQPPHEHEMLRHPVFGTPYPR--DLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQW 1536

Query: 245  LGSFPFLPGG 254
            L   P + GG
Sbjct: 1537 LHGHPHMHGG 1546



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 39/164 (23%), Positives = 56/164 (34%), Gaps = 11/164 (6%)

Query: 203 PTEGR------RSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPP 256
           P+EG       RS    G + P+     +RS    + +P    +          L   PP
Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739

Query: 257 EYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPV 316
                    P     PP   P  P+ G  P A +  P G  +  +     +  + P P  
Sbjct: 740 ALQAPTGVTPAPSSAPPG-TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 798

Query: 317 SI-KSERLSP-APGGPGDFPKTFPYPLL--LARSLAEPLRPGPA 356
            I ++  L P  P  P   P   P+P L  L  S  +P  P  A
Sbjct: 799 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 842


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 75/224 (33%), Positives = 85/224 (37%), Gaps = 36/224 (16%)

Query: 126  PRPRLYPAAPAM-----PSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180
            PR +  P AP       P P      LP P           P  S PSPF   A    PP
Sbjct: 913  PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHP-----PHLSGPSPFSMNANLPPPP 967

Query: 181  GLVHPLFSPS--HLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSL----YSGLQN 234
             L  PL S S  H  S  PPPL L  + +   LP   A P G L  S++L     S    
Sbjct: 968  AL-KPLSSLSTHHPPSAHPPPLQLMPQSQ--PLPSSPAQPPG-LTQSQNLPPPPASHPPT 1023

Query: 235  PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294
                  P PP    PF+PGGPP      PP  P    PP      P     PP   +  S
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPA----GPGTSAQPPCSGAAAS 1076

Query: 295  GGRSLGEEGPPTRGASPPTPPVSIKSERLSPA--PGGPGDFPKT 336
            GG   G       G+S P P V IK E L  A  P  P   P++
Sbjct: 1077 GGSIAG-------GSSCPLPTVQIKEEALDDAEEPESPPPPPRS 1113



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 68/257 (26%), Positives = 89/257 (34%), Gaps = 28/257 (10%)

Query: 123  PAL-PRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPG 181
            PAL P+    P  P  PSP      L      PS    A P      P  P + +AGP  
Sbjct: 804  PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL- 862

Query: 182  LVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGG----LAGPRGGLN--TSRSLYSGLQNP 235
            L HP           P P  LP +  +   P G     A P   L    S+S     Q P
Sbjct: 863  LQHP---------GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913

Query: 236  CSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQP--SRGDGPPAVSSQP 293
                 P  PL      P  PP   +   P P     PP L+   P     + PP  + +P
Sbjct: 914  REQPLPPAPLAMPHIKP--PPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKP 971

Query: 294  SGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTF---PYPLLLARSLAEP 350
                SL    PP+  A PP   +  +S+ L  +P  P    ++    P P     +    
Sbjct: 972  LS--SLSTHHPPS--AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQ 1027

Query: 351  LRPGPALRRLPLADGWP 367
            + P P   + P   G P
Sbjct: 1028 VAPQPPFAQHPFVPGGP 1044



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 71/254 (27%), Positives = 89/254 (35%), Gaps = 52/254 (20%)

Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180
           G P LP P   P+A A+P               P G   A  A ++P    P AP     
Sbjct: 757 GTPQLPTPGPTPSATAVP---------------PQGSPTASQAPNQPQ--APTAPVPHTH 799

Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240
               P   P    S  PPP   P       L G    P    +    L+   Q P     
Sbjct: 800 IQQAPALHPQRPPSPHPPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHG--QGP----- 851

Query: 241 PGP-PLGSFPFL--PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGP----PAVSSQ- 292
           PGP  L + P L  PG P  +GL           PP  +  Q   G  P    P  S Q 
Sbjct: 852 PGPHSLQAGPLLQHPGPPQPFGL-----------PPQASQGQAPLGTSPAAAYPHTSLQL 900

Query: 293 PSGGRSLGEEGPPTRGASPPTPPV--SIKSERLSPAPGGPGDFPKTFPYPLLLAR----S 346
           P+   +L  + PP     PP P     IK    +P P  P   P+   +P  L+     S
Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA--PQAHKHPPHLSGPSPFS 958

Query: 347 LAEPLRPGPALRRL 360
           +   L P PAL+ L
Sbjct: 959 MNANLPPPPALKPL 972



 Score = 35.4 bits (80), Expect = 0.082
 Identities = 50/162 (30%), Positives = 61/162 (37%), Gaps = 43/162 (26%)

Query: 125  LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVH 184
            +P+ +  P++PA P        LPPP           PA   P+     AP+  PP   H
Sbjct: 991  MPQSQPLPSSPAQPPGLTQSQNLPPP-----------PASHPPTGLHQVAPQ--PPFAQH 1037

Query: 185  PLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCS--TATPG 242
            P F P       PPP+  PT    S  P   AGP           +  Q PCS   A+ G
Sbjct: 1038 P-FVPG-----GPPPITPPTCPSTSTPP---AGPG----------TSAQPPCSGAAASGG 1078

Query: 243  PPLG--SFPFLPGGPPEYGLGD------PPPPPGLLQP-PTL 275
               G  S P       E  L D      PPPPP    P PT+
Sbjct: 1079 SIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTV 1120



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 20/54 (37%), Positives = 25/54 (46%), Gaps = 2/54 (3%)

Query: 240  TPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDG--PPAVSS 291
            T GP L  FP+ PG  P   LG PP    +L+ P      P    G  PP +S+
Sbjct: 1460 TAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSA 1513



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 47/190 (24%), Positives = 71/190 (37%), Gaps = 14/190 (7%)

Query: 75   PHESRTNTDILETLKRRGIGLDGPELEPDEG-PEEPGEK---FRRLAGEGGDPALPRPRL 130
            PH   +    L  L+R  + L GP+L P+   P+    +     R+A    DP L R ++
Sbjct: 1361 PHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDP-LARLQM 1419

Query: 131  YPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAG----PPG-LVHP 185
            +   P       ++  L     DP   G A P      P   A P       PPG L +P
Sbjct: 1420 FNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPL-TAGPHLARFPYPPGTLPNP 1478

Query: 186  LF-SPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPP 244
            L   P H       P++     R  DLPG +  P    +  +++++        A     
Sbjct: 1479 LLGQPPHEHEMLRHPVFGTPYPR--DLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQW 1536

Query: 245  LGSFPFLPGG 254
            L   P + GG
Sbjct: 1537 LHGHPHMHGG 1546



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 39/164 (23%), Positives = 56/164 (34%), Gaps = 11/164 (6%)

Query: 203 PTEGR------RSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPP 256
           P+EG       RS    G + P+     +RS    + +P    +          L   PP
Sbjct: 680 PSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 739

Query: 257 EYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPV 316
                    P     PP   P  P+ G  P A +  P G  +  +     +  + P P  
Sbjct: 740 ALQAPTGVTPAPSSAPPG-TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHT 798

Query: 317 SI-KSERLSP-APGGPGDFPKTFPYPLL--LARSLAEPLRPGPA 356
            I ++  L P  P  P   P   P+P L  L  S  +P  P  A
Sbjct: 799 HIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHA 842


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 68.6 bits (166), Expect = 9e-12
 Identities = 85/269 (31%), Positives = 102/269 (37%), Gaps = 61/269 (22%)

Query: 94   GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALP----------RPRLYPAAPAMPSPD 141
            GL GP+ EP     P  PG K     G  GDP LP          +P L P  P  P P 
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIK-----GSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPP 1130

Query: 142  VVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAP-------KAGPPGLVHPLFSPSHLTS 194
               G   PPG +P   GE  P      P +P  P       + G PG       P     
Sbjct: 1131 GPKGISGPPG-NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 195  KTPPPLYLP-TEGRRSD--LPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLG 246
              P P  LP   G++ D  LPG     GL GP+G        + G+Q P     PGPP  
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG--EPGFHGFPGVQGP-----PGPPGS 1242

Query: 247  SFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPT 306
              P L G     G   PP  PGL  P           +GPP +   P  G   GE+G P 
Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGLPGP-----------EGPPGL---PGNGGIKGEKGNPG 1288

Query: 307  RGASPPTPPVSIKSERLSPA----PGGPG 331
            +   P  P   +K ++  P     PG PG
Sbjct: 1289 QPGLPGLP--GLKGDQGPPGLQGNPGRPG 1315



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 89/310 (28%), Positives = 106/310 (34%), Gaps = 53/310 (17%)

Query: 94  GLDGPELEPDEGPEEPGEK-FRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGC 152
           G+ GP+ +P +   +PG+       G  GD  LP     P  P +P    + G+   PG 
Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG---IPGSKGEPGI 703

Query: 153 DPSGL-GEALPAQSRPSPFRPAAPKA-GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSD 210
              GL G   P      P  P AP   G  GL  P   P     K  P   LP       
Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763

Query: 211 LPG--GLAGPRGGLN-------TSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLG 261
           LPG  G  GP+G            R+   GL  P     P    G  P  P G P  G+ 
Sbjct: 764 LPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG--PMGPPGLPGIGVQ 821

Query: 262 DPPPPPGLLQP---PTLAPWQPSRGD---------GPPAVSSQPSGGRSLGEEGPP---- 305
            PP PPG+  P   P L      +GD         GPP     P    + G  GPP    
Sbjct: 822 GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 306 ------------TRG----ASPPTPPVSIKSERLSPAPGGPGD----FPKTFPYPLLLAR 345
                       T+G      PP PP  +     S  PG  GD         P P     
Sbjct: 882 LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 346 SLAEPLRPGP 355
           S  EP  PGP
Sbjct: 942 SKGEPGLPGP 951



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 70/245 (28%), Positives = 89/245 (36%), Gaps = 57/245 (23%)

Query: 106  PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQS 165
            P +PG+    L+G+ G P  P P+  P  P  P      G + PPG     L   +    
Sbjct: 987  PGDPGQP--GLSGQPGLPGPPGPKGNPGLPGQP------GLIGPPG-----LKGTIGDMG 1033

Query: 166  RPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPG-------GLAGP 218
             P P        GPPG       PS +  +   P     +G + D PG       GL GP
Sbjct: 1034 FPGP----QGVEGPPG-------PSGVPGQPGSPGLPGQKGDKGD-PGISSIGLPGLPGP 1081

Query: 219  RG-----GLNTSRSLYSGLQNPCSTATPGPP-------LGSFPFLPGGPPEYGLGDPPPP 266
            +G     G   +  +   + +P     PG P       L  FP  PG P   G+  PP  
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141

Query: 267  PGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326
            PGL   P      P  G G P     P      GE+G P +   P   P   K E   P 
Sbjct: 1142 PGLPGEP-----GPVGGGGHPGQPGPP------GEKGKPGQDGIP--GPAGQKGEPGQPG 1188

Query: 327  PGGPG 331
             G PG
Sbjct: 1189 FGNPG 1193



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 78/276 (28%), Positives = 94/276 (34%), Gaps = 47/276 (17%)

Query: 92  GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAA------------PAMPS 139
           G+  D  EL     P  PG       G+ G P LP P+  P              P +P 
Sbjct: 555 GMKGDKGELGSPGAPGLPG--LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612

Query: 140 PDVVYGALPPPGCDPSG-LGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP 198
                G + PPG  P G +GE           +  A   G PG+  P   P    ++   
Sbjct: 613 LPGNIGPMGPPGFGPPGPVGE--------KGIQGVAGNPGQPGIPGPKGDPGQTITQPGK 664

Query: 199 PLYLPTEGRRSD--LPG--GLAGPRG--GLNTSRSLYSGLQNPCSTATPGPP-------L 245
           P      GR  D  LPG  GL G  G  G+  S+    G         PGPP       +
Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK----GEPGIPGIGLPGPPGPKGFPGI 720

Query: 246 GSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAV-----SSQPSGGRSL- 299
              P  PG P   GL  PP PPG   P     +      GPP +     +  P G R   
Sbjct: 721 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 780

Query: 300 GEEGPPTRGASPPTP-PVSIKSERLSPAPGGPGDFP 334
           G  GPP R      P P         P P GP   P
Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 84/265 (31%), Positives = 92/265 (34%), Gaps = 75/265 (28%)

Query: 94  GLDGPELEP-------DEG-PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145
           G  GPE  P       D+G P  PG K     G  G P LP     P  P MP  D   G
Sbjct: 63  GFPGPEGPPGPRGQKGDDGIPGPPGPK-----GIRGPPGLPGFPGTPGLPGMPGHDGAPG 117

Query: 146 ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSP-SHLTSKTPPPLYLP 203
               PGC+ +      P     SP  P      GPPG+      P S + S  P P   P
Sbjct: 118 PQGIPGCNGTKGERGFPG----SPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP 173

Query: 204 TEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDP 263
                     G  GP G          GL  P  T  PG P+G     P GPP  GL  P
Sbjct: 174 ----------GYPGPPG--------IQGLPGP--TGIPG-PIG-----PPGPP--GLMGP 205

Query: 264 PPPPGL----------------------LQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGE 301
           P PPGL                      LQ P   P Q S    P  V  Q       G+
Sbjct: 206 PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD 265

Query: 302 EGPP----TRGASPPTPPVSIKSER 322
            GPP     RG  PP PP   K E+
Sbjct: 266 RGPPGPPGIRG--PPGPPGGEKGEK 288



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 70/220 (31%), Positives = 78/220 (35%), Gaps = 67/220 (30%)

Query: 94   GLDG-PELEPDEGPE----EPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALP 148
            GL G P L+ D+GP      PG     L G  GDP LP     P  P M  P  V G+  
Sbjct: 1291 GLPGLPGLKGDQGPPGLQGNPGRP--GLNGMKGDPGLPG---VPGFPGMKGPSGVPGSAG 1345

Query: 149  PPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRR 208
            P G +P  +G                   GPPGL  P      +     PP      G +
Sbjct: 1346 PEG-EPGLIGPP-----------------GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK 1387

Query: 209  SDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPP----LGSF---------PFLPGGP 255
                 GL GP+G          GL  P  T  PG P    L  F         P LPG P
Sbjct: 1388 -----GLPGPQGP--------QGLPGP--TGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP 1432

Query: 256  PEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSG 295
               GL  PP P GL  PP           GPP  SS   G
Sbjct: 1433 GTRGLDGPPGPDGLQGPP-----------GPPGTSSVAHG 1461



 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 85/290 (29%), Positives = 102/290 (35%), Gaps = 66/290 (22%)

Query: 94   GLDG-PELEPDEGPE-------EPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145
            GLDG P  + D GP         PG     + G  G P +P P   P    +P      G
Sbjct: 790  GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEK---G 846

Query: 146  ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSPSHLTSKTPPPLYLPT 204
               PPG D  G     P   R SP  P AP   GPPG      SP  L  K     +  T
Sbjct: 847  DPGPPGLDVPG-----PPGERGSPGIPGAPGPIGPPG------SPG-LPGKAGASGFPGT 894

Query: 205  EGRRSDL-PGGLAGPRG--------GLNTSRSLYS--GLQNPCST-------ATPGPPLG 246
            +G    + P G  GP G        GL     L    GL  P            PGPP  
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 247  ---------------SFPFLPG--GPPEY-GLGDPPPPPGLLQPPTLAPWQPSRGD---- 284
                             P +PG  GP  Y GL   P  PGL   P L      +G+    
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 285  GPPAVSSQPSGGRSLGEEG-PPTRGASPPTPPVSIKSERLSPA-PGGPGD 332
            G P +   P    ++G+ G P  +G   P  P  +  +  SP  PG  GD
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 89/338 (26%), Positives = 109/338 (32%), Gaps = 96/338 (28%)

Query: 94  GLDGPELEPD-EGPE-EPGEKFRR-LAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPP 150
           GL GP   P   G + EPG      L G  G+P  P P   P    +P P  + G + PP
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP---PGIQGLPGPTGIPGPIGPP 197

Query: 151 GCDPSGLGEALPAQSRPSP-------FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLP 203
           G  P GL         P P       F+    + G  GL  P   P  ++ +  P   + 
Sbjct: 198 G--PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP---ID 252

Query: 204 TEGRRSD--LPG--------GLAGPRG------------------------GLNTSRSLY 229
            E ++ D  LPG        G+ GP G                        G N    + 
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 230 SGLQNPC---------------STATPGPP------------LGS-----FPFLPGGPPE 257
               +P                 T  PGPP            +G       P LPG   E
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 258 YGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVS 317
            G      PPGL  PP  A        GPP     P      G+EGPP  G S P PP  
Sbjct: 373 RGFPGIQGPPGLPGPPGAAVM------GPPGPPGFPGERGQKGDEGPP--GISIPGPPGL 424

Query: 318 IKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGP 355
                    PG PG      P     +  + EP  PGP
Sbjct: 425 DGQPGAPGLPGPPGPAGPHIP----PSDEICEPGPPGP 458



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 91/323 (28%), Positives = 110/323 (34%), Gaps = 73/323 (22%)

Query: 94  GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151
           G  G + EP +   P + GE      G+ G P LP    YP  P         G   PPG
Sbjct: 286 GEKGEQGEPGKRGKPGKDGEN-----GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340

Query: 152 CDPSGL-----GEALPAQSRPSPFRPAAPKA----------GPPGLVHPLFSPSHLTSKT 196
             P GL     G  +    + +   P  P            GPPGL  P   P       
Sbjct: 341 --PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP---PGAAVMGP 395

Query: 197 PPPLYLPTE-GRRSDL--PG-GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLP 252
           P P   P E G++ D   PG  + GP G          G   P +   PGPP  + P +P
Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPG--------LDG--QPGAPGLPGPPGPAGPHIP 445

Query: 253 GGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD-----------------GPPAVSSQPSG 295
               E     PP PPG      L   Q  +GD                 G P +   P  
Sbjct: 446 PS-DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGP 504

Query: 296 GRSLGEEGPP-TRGASPPTPPVSIKSERLSPAPGGPGDFP---------KTFPYPLLLAR 345
             SLG  G    +G +  T P  +    +  APG PG FP          TFP       
Sbjct: 505 PGSLGFPGQKGEKGQAGATGPKGLPG--IPGAPGAPG-FPGSKGEPGDILTFPGMKGDKG 561

Query: 346 SLAEPLRPG-PALRRLPLADGWP 367
            L  P  PG P L   P  DG P
Sbjct: 562 ELGSPGAPGLPGLPGTPGQDGLP 584


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 74/231 (32%), Positives = 91/231 (39%), Gaps = 20/231 (8%)

Query: 126  PRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPA---APKAGPPGL 182
            PRP   PA P    P      LP P   P+G  + +PAQ   S   PA   AP+ GP   
Sbjct: 897  PRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQ 956

Query: 183  VHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPG 242
             HP   PS      PP   LP +      P        GL   +S Y     P     P 
Sbjct: 957  PHPQPHPSQAFGPQPPQQPLPLQH-----PHLFPPQAPGLLPPQSPYPYAPQPGVLGQPP 1011

Query: 243  PPLGS--FPFLPGGP-PEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRS- 298
            PPL +  +P     P P +    P P PG  QPP      P    G PA S++P G ++ 
Sbjct: 1012 PPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPP-----HPPLAYG-PAPSTRPMGPQAA 1065

Query: 299  -LGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLA 348
             L   GP + G S P+P + + S   SP PG     P     P  L R  A
Sbjct: 1066 PLTIRGPSSAGQSTPSPHL-VPSPAPSPGPGPVPPRPPAAEPPPCLRRGAA 1115



 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 75/267 (28%), Positives = 86/267 (32%), Gaps = 56/267 (20%)

Query: 115  RLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPS---GLGEALPAQSRPSPFR 171
            R  G    P  P P LYPA    P   +V  + P  G   S   G+G             
Sbjct: 806  RAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVG------------- 852

Query: 172  PAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSG 231
            PA P AG P    P FS   L     P      +  ++ +P   A               
Sbjct: 853  PAPPVAGLPSAPPPQFSGPELAMAVRPAT-TTVDSIQAPIPSHTA--------------- 896

Query: 232  LQNPCSTATPGPPLGSFPFLPGGPPEYGLGDP-PPPPGLLQPPTLAPWQPSRGDGPPAVS 290
               P    TP PP   FP     PP   L  P   P G  QP    P Q     G PA  
Sbjct: 897  ---PRPNPTPAPPPPCFPV----PPPQPLPTPYTYPAGAKQP---IPAQHHFSSGIPAGF 946

Query: 291  SQPSGGRSLGEEGPP----TRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARS 346
              P  G        P      G  PP  P+ ++   L P P  PG  P   PYP      
Sbjct: 947  PAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFP-PQAPGLLPPQSPYPYAPQPG 1005

Query: 347  -LAEP-------LRPGPALRRLPLADG 365
             L +P       L PGPA   LP   G
Sbjct: 1006 VLGQPPPPLHTQLYPGPAQDPLPAHSG 1032



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 32/118 (27%), Positives = 41/118 (34%), Gaps = 33/118 (27%)

Query: 124  ALPRPRLYPAAPAMPSPDVVYGALP---PPGCD--------PSGLGEALPA--------- 163
            ALP P   P  P  P P + YG  P   P G          PS  G++ P+         
Sbjct: 1033 ALPFPS--PGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAP 1090

Query: 164  QSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGG 221
               P P  P  P A PP  +    + + L S +P   +           GG   P GG
Sbjct: 1091 SPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQH-----------GGTQSPGGG 1137



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 6/59 (10%)

Query: 124  ALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPS--PFRPAAPKAGPP 180
            +LP P   P  P    P+    + P P   P  L   LP   +P   P  P AP +GPP
Sbjct: 1519 SLPGPAEPPGLPPASLPE----STPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPP 1573


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 86/269 (31%), Positives = 103/269 (38%), Gaps = 55/269 (20%)

Query: 94   GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALP----------RPRLYPAAPAMPSPD 141
            GL GP+ EP     P  PG K     G  GDP LP          +P L P  P  P P 
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIK-----GSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPP 1130

Query: 142  VVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAP-------KAGPPGLVHPLFSPSHLTS 194
               G   PPG +P   GE  P      P +P  P       + G PG       P     
Sbjct: 1131 GPKGISGPPG-NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 195  KTPPPLYLP-TEGRRSD--LPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLG 246
              P P  LP   G++ D  LPG     GL GP+G        + G+Q P     PGPP  
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG--EPGFHGFPGVQGP-----PGPPGS 1242

Query: 247  SFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPT 306
              P L G     G   PP  PG    PT     P   +GPP +   P  G   GE+G P 
Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPG----PTGFQGLPG-PEGPPGL---PGNGGIKGEKGNPG 1294

Query: 307  RGASPPTPPVSIKSERLSPA----PGGPG 331
            +   P  P   +K ++  P     PG PG
Sbjct: 1295 QPGLPGLP--GLKGDQGPPGLQGNPGRPG 1321



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 89/310 (28%), Positives = 106/310 (34%), Gaps = 53/310 (17%)

Query: 94  GLDGPELEPDEGPEEPGEK-FRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGC 152
           G+ GP+ +P +   +PG+       G  GD  LP     P  P +P    + G+   PG 
Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG---IPGSKGEPGI 703

Query: 153 DPSGL-GEALPAQSRPSPFRPAAPKA-GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSD 210
              GL G   P      P  P AP   G  GL  P   P     K  P   LP       
Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763

Query: 211 LPG--GLAGPRGGLN-------TSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLG 261
           LPG  G  GP+G            R+   GL  P     P    G  P  P G P  G+ 
Sbjct: 764 LPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG--PMGPPGLPGIGVQ 821

Query: 262 DPPPPPGLLQP---PTLAPWQPSRGD---------GPPAVSSQPSGGRSLGEEGPP---- 305
            PP PPG+  P   P L      +GD         GPP     P    + G  GPP    
Sbjct: 822 GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 306 ------------TRG----ASPPTPPVSIKSERLSPAPGGPGD----FPKTFPYPLLLAR 345
                       T+G      PP PP  +     S  PG  GD         P P     
Sbjct: 882 LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 346 SLAEPLRPGP 355
           S  EP  PGP
Sbjct: 942 SKGEPGLPGP 951



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 70/245 (28%), Positives = 89/245 (36%), Gaps = 57/245 (23%)

Query: 106  PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQS 165
            P +PG+    L+G+ G P  P P+  P  P  P      G + PPG     L   +    
Sbjct: 987  PGDPGQP--GLSGQPGLPGPPGPKGNPGLPGQP------GLIGPPG-----LKGTIGDMG 1033

Query: 166  RPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPG-------GLAGP 218
             P P        GPPG       PS +  +   P     +G + D PG       GL GP
Sbjct: 1034 FPGP----QGVEGPPG-------PSGVPGQPGSPGLPGQKGDKGD-PGISSIGLPGLPGP 1081

Query: 219  RG-----GLNTSRSLYSGLQNPCSTATPGPP-------LGSFPFLPGGPPEYGLGDPPPP 266
            +G     G   +  +   + +P     PG P       L  FP  PG P   G+  PP  
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141

Query: 267  PGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326
            PGL   P      P  G G P     P      GE+G P +   P   P   K E   P 
Sbjct: 1142 PGLPGEP-----GPVGGGGHPGQPGPP------GEKGKPGQDGIP--GPAGQKGEPGQPG 1188

Query: 327  PGGPG 331
             G PG
Sbjct: 1189 FGNPG 1193



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 78/276 (28%), Positives = 94/276 (34%), Gaps = 47/276 (17%)

Query: 92  GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAA------------PAMPS 139
           G+  D  EL     P  PG       G+ G P LP P+  P              P +P 
Sbjct: 555 GMKGDKGELGSPGAPGLPG--LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612

Query: 140 PDVVYGALPPPGCDPSG-LGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP 198
                G + PPG  P G +GE           +  A   G PG+  P   P    ++   
Sbjct: 613 LPGNIGPMGPPGFGPPGPVGE--------KGIQGVAGNPGQPGIPGPKGDPGQTITQPGK 664

Query: 199 PLYLPTEGRRSD--LPG--GLAGPRG--GLNTSRSLYSGLQNPCSTATPGPP-------L 245
           P      GR  D  LPG  GL G  G  G+  S+    G         PGPP       +
Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK----GEPGIPGIGLPGPPGPKGFPGI 720

Query: 246 GSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAV-----SSQPSGGRSL- 299
              P  PG P   GL  PP PPG   P     +      GPP +     +  P G R   
Sbjct: 721 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 780

Query: 300 GEEGPPTRGASPPTP-PVSIKSERLSPAPGGPGDFP 334
           G  GPP R      P P         P P GP   P
Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 84/265 (31%), Positives = 92/265 (34%), Gaps = 75/265 (28%)

Query: 94  GLDGPELEP-------DEG-PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145
           G  GPE  P       D+G P  PG K     G  G P LP     P  P MP  D   G
Sbjct: 63  GFPGPEGPPGPRGQKGDDGIPGPPGPK-----GIRGPPGLPGFPGTPGLPGMPGHDGAPG 117

Query: 146 ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSP-SHLTSKTPPPLYLP 203
               PGC+ +      P     SP  P      GPPG+      P S + S  P P   P
Sbjct: 118 PQGIPGCNGTKGERGFPG----SPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP 173

Query: 204 TEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDP 263
                     G  GP G          GL  P  T  PG P+G     P GPP  GL  P
Sbjct: 174 ----------GYPGPPG--------IQGLPGP--TGIPG-PIG-----PPGPP--GLMGP 205

Query: 264 PPPPGL----------------------LQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGE 301
           P PPGL                      LQ P   P Q S    P  V  Q       G+
Sbjct: 206 PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD 265

Query: 302 EGPP----TRGASPPTPPVSIKSER 322
            GPP     RG  PP PP   K E+
Sbjct: 266 RGPPGPPGIRG--PPGPPGGEKGEK 288



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 72/248 (29%), Positives = 88/248 (35%), Gaps = 68/248 (27%)

Query: 92   GIGLDGPELEPDEGPEEPGEK-----FRRLAGEGGDPALPR------PRLYPAAPAMPSP 140
            G  L+GP+  P  GP+ P  +     F+ L G  G P LP        +  P  P +P  
Sbjct: 1244 GPALEGPKGNP--GPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1301

Query: 141  DVVYGALPPPGC--------------DPSGLG-EALPAQSRPSPFRPAAPKAGPPGLVHP 185
              + G   PPG               DP   G    P    PS    +A   G PGL+ P
Sbjct: 1302 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1361

Query: 186  LFSPSHLTSKTPPPLYLPTEGRRSDLPG-----GLAGPRGGLNTSRSLYSGLQNPCSTAT 240
               P  L   +   + +  +     +PG     GL GP+G          GL  P  T  
Sbjct: 1362 P-GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP--------QGLPGP--TGP 1410

Query: 241  PGPP----LGSF---------PFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPP 287
            PG P    L  F         P LPG P   GL  PP P GL  PP           GPP
Sbjct: 1411 PGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP-----------GPP 1459

Query: 288  AVSSQPSG 295
              SS   G
Sbjct: 1460 GTSSVAHG 1467



 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 85/290 (29%), Positives = 102/290 (35%), Gaps = 66/290 (22%)

Query: 94   GLDG-PELEPDEGPE-------EPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145
            GLDG P  + D GP         PG     + G  G P +P P   P    +P      G
Sbjct: 790  GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEK---G 846

Query: 146  ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSPSHLTSKTPPPLYLPT 204
               PPG D  G     P   R SP  P AP   GPPG      SP  L  K     +  T
Sbjct: 847  DPGPPGLDVPG-----PPGERGSPGIPGAPGPIGPPG------SPG-LPGKAGASGFPGT 894

Query: 205  EGRRSDL-PGGLAGPRG--------GLNTSRSLYS--GLQNPCST-------ATPGPPLG 246
            +G    + P G  GP G        GL     L    GL  P            PGPP  
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 247  ---------------SFPFLPG--GPPEY-GLGDPPPPPGLLQPPTLAPWQPSRGD---- 284
                             P +PG  GP  Y GL   P  PGL   P L      +G+    
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 285  GPPAVSSQPSGGRSLGEEG-PPTRGASPPTPPVSIKSERLSPA-PGGPGD 332
            G P +   P    ++G+ G P  +G   P  P  +  +  SP  PG  GD
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 89/338 (26%), Positives = 109/338 (32%), Gaps = 96/338 (28%)

Query: 94  GLDGPELEPD-EGPE-EPGEKFRR-LAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPP 150
           GL GP   P   G + EPG      L G  G+P  P P   P    +P P  + G + PP
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP---PGIQGLPGPTGIPGPIGPP 197

Query: 151 GCDPSGLGEALPAQSRPSP-------FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLP 203
           G  P GL         P P       F+    + G  GL  P   P  ++ +  P   + 
Sbjct: 198 G--PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP---ID 252

Query: 204 TEGRRSD--LPG--------GLAGPRG------------------------GLNTSRSLY 229
            E ++ D  LPG        G+ GP G                        G N    + 
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 230 SGLQNPC---------------STATPGPP------------LGS-----FPFLPGGPPE 257
               +P                 T  PGPP            +G       P LPG   E
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 258 YGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVS 317
            G      PPGL  PP  A        GPP     P      G+EGPP  G S P PP  
Sbjct: 373 RGFPGIQGPPGLPGPPGAAVM------GPPGPPGFPGERGQKGDEGPP--GISIPGPPGL 424

Query: 318 IKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGP 355
                    PG PG      P     +  + EP  PGP
Sbjct: 425 DGQPGAPGLPGPPGPAGPHIP----PSDEICEPGPPGP 458



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 91/323 (28%), Positives = 110/323 (34%), Gaps = 73/323 (22%)

Query: 94  GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151
           G  G + EP +   P + GE      G+ G P LP    YP  P         G   PPG
Sbjct: 286 GEKGEQGEPGKRGKPGKDGEN-----GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340

Query: 152 CDPSGL-----GEALPAQSRPSPFRPAAPKA----------GPPGLVHPLFSPSHLTSKT 196
             P GL     G  +    + +   P  P            GPPGL  P   P       
Sbjct: 341 --PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP---PGAAVMGP 395

Query: 197 PPPLYLPTE-GRRSDL--PG-GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLP 252
           P P   P E G++ D   PG  + GP G          G   P +   PGPP  + P +P
Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPG--------LDG--QPGAPGLPGPPGPAGPHIP 445

Query: 253 GGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD-----------------GPPAVSSQPSG 295
               E     PP PPG      L   Q  +GD                 G P +   P  
Sbjct: 446 PS-DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGP 504

Query: 296 GRSLGEEGPP-TRGASPPTPPVSIKSERLSPAPGGPGDFP---------KTFPYPLLLAR 345
             SLG  G    +G +  T P  +    +  APG PG FP          TFP       
Sbjct: 505 PGSLGFPGQKGEKGQAGATGPKGLPG--IPGAPGAPG-FPGSKGEPGDILTFPGMKGDKG 561

Query: 346 SLAEPLRPG-PALRRLPLADGWP 367
            L  P  PG P L   P  DG P
Sbjct: 562 ELGSPGAPGLPGLPGTPGQDGLP 584


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 84/269 (31%), Positives = 101/269 (37%), Gaps = 58/269 (21%)

Query: 94   GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALP----------RPRLYPAAPAMPSPD 141
            GL GP+ EP     P  PG K     G  GDP LP          +P L P  P  P P 
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIK-----GSVGDPGLPGLPGTPGAKGQPGL-PGFPGTPGPP 1130

Query: 142  VVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAP-------KAGPPGLVHPLFSPSHLTS 194
               G   PPG +P   GE  P      P +P  P       + G PG       P     
Sbjct: 1131 GPKGISGPPG-NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 195  KTPPPLYLP-TEGRRSD--LPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLG 246
              P P  LP   G++ D  LPG     GL GP+G        + G+Q P     PGPP  
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG--EPGFHGFPGVQGP-----PGPPGS 1242

Query: 247  SFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPT 306
              P L G     G   PP  PG    P          +GPP +   P  G   GE+G P 
Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGFQGLPG--------PEGPPGL---PGNGGIKGEKGNPG 1291

Query: 307  RGASPPTPPVSIKSERLSPA----PGGPG 331
            +   P  P   +K ++  P     PG PG
Sbjct: 1292 QPGLPGLP--GLKGDQGPPGLQGNPGRPG 1318



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 89/310 (28%), Positives = 106/310 (34%), Gaps = 53/310 (17%)

Query: 94  GLDGPELEPDEGPEEPGEK-FRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGC 152
           G+ GP+ +P +   +PG+       G  GD  LP     P  P +P    + G+   PG 
Sbjct: 647 GIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG---IPGSKGEPGI 703

Query: 153 DPSGL-GEALPAQSRPSPFRPAAPKA-GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSD 210
              GL G   P      P  P AP   G  GL  P   P     K  P   LP       
Sbjct: 704 PGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763

Query: 211 LPG--GLAGPRGGLN-------TSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLG 261
           LPG  G  GP+G            R+   GL  P     P    G  P  P G P  G+ 
Sbjct: 764 LPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG--PMGPPGLPGIGVQ 821

Query: 262 DPPPPPGLLQP---PTLAPWQPSRGD---------GPPAVSSQPSGGRSLGEEGPP---- 305
            PP PPG+  P   P L      +GD         GPP     P    + G  GPP    
Sbjct: 822 GPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 306 ------------TRG----ASPPTPPVSIKSERLSPAPGGPGD----FPKTFPYPLLLAR 345
                       T+G      PP PP  +     S  PG  GD         P P     
Sbjct: 882 LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 346 SLAEPLRPGP 355
           S  EP  PGP
Sbjct: 942 SKGEPGLPGP 951



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 70/245 (28%), Positives = 89/245 (36%), Gaps = 57/245 (23%)

Query: 106  PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQS 165
            P +PG+    L+G+ G P  P P+  P  P  P      G + PPG     L   +    
Sbjct: 987  PGDPGQP--GLSGQPGLPGPPGPKGNPGLPGQP------GLIGPPG-----LKGTIGDMG 1033

Query: 166  RPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPG-------GLAGP 218
             P P        GPPG       PS +  +   P     +G + D PG       GL GP
Sbjct: 1034 FPGP----QGVEGPPG-------PSGVPGQPGSPGLPGQKGDKGD-PGISSIGLPGLPGP 1081

Query: 219  RG-----GLNTSRSLYSGLQNPCSTATPGPP-------LGSFPFLPGGPPEYGLGDPPPP 266
            +G     G   +  +   + +P     PG P       L  FP  PG P   G+  PP  
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141

Query: 267  PGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326
            PGL   P      P  G G P     P      GE+G P +   P   P   K E   P 
Sbjct: 1142 PGLPGEP-----GPVGGGGHPGQPGPP------GEKGKPGQDGIP--GPAGQKGEPGQPG 1188

Query: 327  PGGPG 331
             G PG
Sbjct: 1189 FGNPG 1193



 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 72/245 (29%), Positives = 88/245 (35%), Gaps = 65/245 (26%)

Query: 92   GIGLDGPELEPDEGPEEPGEK--FRRLAGEGGDPALPR------PRLYPAAPAMPSPDVV 143
            G  L+GP+  P  GP+ P  +  F+ L G  G P LP        +  P  P +P    +
Sbjct: 1244 GPALEGPKGNP--GPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301

Query: 144  YGALPPPGC--------------DPSGLG-EALPAQSRPSPFRPAAPKAGPPGLVHPLFS 188
             G   PPG               DP   G    P    PS    +A   G PGL+ P   
Sbjct: 1302 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP-G 1360

Query: 189  PSHLTSKTPPPLYLPTEGRRSDLPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGP 243
            P  L   +   + +  +     +PG     GL GP+G          GL  P  T  PG 
Sbjct: 1361 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGP--------QGLPGP--TGPPGD 1410

Query: 244  P----LGSF---------PFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVS 290
            P    L  F         P LPG P   GL  PP P GL  PP           GPP  S
Sbjct: 1411 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP-----------GPPGTS 1459

Query: 291  SQPSG 295
            S   G
Sbjct: 1460 SVAHG 1464



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 78/276 (28%), Positives = 94/276 (34%), Gaps = 47/276 (17%)

Query: 92  GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAA------------PAMPS 139
           G+  D  EL     P  PG       G+ G P LP P+  P              P +P 
Sbjct: 555 GMKGDKGELGSPGAPGLPG--LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612

Query: 140 PDVVYGALPPPGCDPSG-LGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP 198
                G + PPG  P G +GE           +  A   G PG+  P   P    ++   
Sbjct: 613 LPGNIGPMGPPGFGPPGPVGE--------KGIQGVAGNPGQPGIPGPKGDPGQTITQPGK 664

Query: 199 PLYLPTEGRRSD--LPG--GLAGPRG--GLNTSRSLYSGLQNPCSTATPGPP-------L 245
           P      GR  D  LPG  GL G  G  G+  S+    G         PGPP       +
Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK----GEPGIPGIGLPGPPGPKGFPGI 720

Query: 246 GSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAV-----SSQPSGGRSL- 299
              P  PG P   GL  PP PPG   P     +      GPP +     +  P G R   
Sbjct: 721 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 780

Query: 300 GEEGPPTRGASPPTP-PVSIKSERLSPAPGGPGDFP 334
           G  GPP R      P P         P P GP   P
Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 84/265 (31%), Positives = 92/265 (34%), Gaps = 75/265 (28%)

Query: 94  GLDGPELEP-------DEG-PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145
           G  GPE  P       D+G P  PG K     G  G P LP     P  P MP  D   G
Sbjct: 63  GFPGPEGPPGPRGQKGDDGIPGPPGPK-----GIRGPPGLPGFPGTPGLPGMPGHDGAPG 117

Query: 146 ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSP-SHLTSKTPPPLYLP 203
               PGC+ +      P     SP  P      GPPG+      P S + S  P P   P
Sbjct: 118 PQGIPGCNGTKGERGFPG----SPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNP 173

Query: 204 TEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDP 263
                     G  GP G          GL  P  T  PG P+G     P GPP  GL  P
Sbjct: 174 ----------GYPGPPG--------IQGLPGP--TGIPG-PIG-----PPGPP--GLMGP 205

Query: 264 PPPPGL----------------------LQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGE 301
           P PPGL                      LQ P   P Q S    P  V  Q       G+
Sbjct: 206 PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD 265

Query: 302 EGPP----TRGASPPTPPVSIKSER 322
            GPP     RG  PP PP   K E+
Sbjct: 266 RGPPGPPGIRG--PPGPPGGEKGEK 288



 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 85/290 (29%), Positives = 102/290 (35%), Gaps = 66/290 (22%)

Query: 94   GLDG-PELEPDEGPE-------EPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYG 145
            GLDG P  + D GP         PG     + G  G P +P P   P    +P      G
Sbjct: 790  GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEK---G 846

Query: 146  ALPPPGCDPSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSPSHLTSKTPPPLYLPT 204
               PPG D  G     P   R SP  P AP   GPPG      SP  L  K     +  T
Sbjct: 847  DPGPPGLDVPG-----PPGERGSPGIPGAPGPIGPPG------SPG-LPGKAGASGFPGT 894

Query: 205  EGRRSDL-PGGLAGPRG--------GLNTSRSLYS--GLQNPCST-------ATPGPPLG 246
            +G    + P G  GP G        GL     L    GL  P            PGPP  
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 247  ---------------SFPFLPG--GPPEY-GLGDPPPPPGLLQPPTLAPWQPSRGD---- 284
                             P +PG  GP  Y GL   P  PGL   P L      +G+    
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 285  GPPAVSSQPSGGRSLGEEG-PPTRGASPPTPPVSIKSERLSPA-PGGPGD 332
            G P +   P    ++G+ G P  +G   P  P  +  +  SP  PG  GD
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 89/338 (26%), Positives = 109/338 (32%), Gaps = 96/338 (28%)

Query: 94  GLDGPELEPD-EGPE-EPGEKFRR-LAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPP 150
           GL GP   P   G + EPG      L G  G+P  P P   P    +P P  + G + PP
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP---PGIQGLPGPTGIPGPIGPP 197

Query: 151 GCDPSGLGEALPAQSRPSP-------FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLP 203
           G  P GL         P P       F+    + G  GL  P   P  ++ +  P   + 
Sbjct: 198 G--PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP---ID 252

Query: 204 TEGRRSD--LPG--------GLAGPRG------------------------GLNTSRSLY 229
            E ++ D  LPG        G+ GP G                        G N    + 
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 230 SGLQNPC---------------STATPGPP------------LGS-----FPFLPGGPPE 257
               +P                 T  PGPP            +G       P LPG   E
Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 258 YGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVS 317
            G      PPGL  PP  A        GPP     P      G+EGPP  G S P PP  
Sbjct: 373 RGFPGIQGPPGLPGPPGAAVM------GPPGPPGFPGERGQKGDEGPP--GISIPGPPGL 424

Query: 318 IKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGP 355
                    PG PG      P     +  + EP  PGP
Sbjct: 425 DGQPGAPGLPGPPGPAGPHIP----PSDEICEPGPPGP 458



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 91/323 (28%), Positives = 110/323 (34%), Gaps = 73/323 (22%)

Query: 94  GLDGPELEPDEG--PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151
           G  G + EP +   P + GE      G+ G P LP    YP  P         G   PPG
Sbjct: 286 GEKGEQGEPGKRGKPGKDGEN-----GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340

Query: 152 CDPSGL-----GEALPAQSRPSPFRPAAPKA----------GPPGLVHPLFSPSHLTSKT 196
             P GL     G  +    + +   P  P            GPPGL  P   P       
Sbjct: 341 --PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP---PGAAVMGP 395

Query: 197 PPPLYLPTE-GRRSDL--PG-GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLP 252
           P P   P E G++ D   PG  + GP G          G   P +   PGPP  + P +P
Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPG--------LDG--QPGAPGLPGPPGPAGPHIP 445

Query: 253 GGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD-----------------GPPAVSSQPSG 295
               E     PP PPG      L   Q  +GD                 G P +   P  
Sbjct: 446 PS-DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGP 504

Query: 296 GRSLGEEGPP-TRGASPPTPPVSIKSERLSPAPGGPGDFP---------KTFPYPLLLAR 345
             SLG  G    +G +  T P  +    +  APG PG FP          TFP       
Sbjct: 505 PGSLGFPGQKGEKGQAGATGPKGLPG--IPGAPGAPG-FPGSKGEPGDILTFPGMKGDKG 561

Query: 346 SLAEPLRPG-PALRRLPLADGWP 367
            L  P  PG P L   P  DG P
Sbjct: 562 ELGSPGAPGLPGLPGTPGQDGLP 584


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 59/189 (31%), Positives = 84/189 (44%), Gaps = 22/189 (11%)

Query: 148 PPPGCDPSGLGEALPAQSRPSPFRPAAPK--AGPPGL-VHPLFSPSHLTSKTPP-----P 199
           PPP   P   G A+ AQ +P+P  P+ P+  A PP L +H +   + +   TPP     P
Sbjct: 712 PPPPPPPPTPGSAM-AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIP 770

Query: 200 LYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYG 259
             LP +     L   +  P     TS    + +    +  TP PP+      P  P  Y 
Sbjct: 771 APLPPQAPPKPLV-TIPAP-----TSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI 824

Query: 260 LGDPPPPPGLLQPPTLAPWQPSRGDGPPA-VSSQPSGGRSLGEEGPPTRGASPPTPPVSI 318
              PP PP  + PPTL   Q      PP+ +S  PS  + +  + PP     PPTPP ++
Sbjct: 825 PPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPP-----PPTPP-AM 878

Query: 319 KSERLSPAP 327
           +S+ L P P
Sbjct: 879 ESQPLKPVP 887



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 56/205 (27%), Positives = 72/205 (35%), Gaps = 36/205 (17%)

Query: 123 PALPRPRLYPAAPAM---PSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGP 179
           P +P  +  PA PA    PSP      +PPP          LP Q       P +P +  
Sbjct: 808 PPVPPAKKQPAFPASYIPPSPPTPPVPVPPP---------TLPKQQSFCAKPPPSPLSPV 858

Query: 180 PGLVHPLFSPSHLTSKTPPPLYLPTEGRR--SDLPGGLAGPRGGLNTSRSLYSGLQNPCS 237
           P +V        + S+ PPP   P    +    +P  +A        ++  +     P S
Sbjct: 859 PSVV------KQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ----PSS 908

Query: 238 TATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGR 297
              P P        P  PPE  L  PPPPP     P  AP  P      P      S G+
Sbjct: 909 IPVPSPDF------PPPPPESSLVFPPPPPS----PVPAPPPPPPPTASPTPDKSGSPGK 958

Query: 298 SLGEEGPPTRGASPPTPP--VSIKS 320
              +   P     PPTP    SIKS
Sbjct: 959 KTSKTSSPGGKKPPPTPQRNSSIKS 983



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 42/131 (32%), Positives = 52/131 (39%), Gaps = 14/131 (10%)

Query: 235 PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294
           P + + P PPL   P  P  PP      PPPPP    PP  +   PS G   P      +
Sbjct: 618 PYTASQPSPPLPPPP--PPPPP------PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669

Query: 295 GGRSLGEEGPPTRGASPPTPPV----SIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEP 350
             R             PPTPPV    S+K + L P P G    P   P P     ++A+ 
Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP-PNGVVPPPPPPPPPPTPGSAMAQ- 727

Query: 351 LRPGPALRRLP 361
           L+P P    LP
Sbjct: 728 LKPAPCAPSLP 738



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 59/257 (22%), Positives = 78/257 (30%), Gaps = 32/257 (12%)

Query: 98  PELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYP--------------AAPAMPSPDVV 143
           P   P   P  PG    +L      P+LP+    P              A P  P P  +
Sbjct: 710 PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI 769

Query: 144 YGALPPPGCD--------PSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSK 195
              LPP            P+      P  ++ +P  P  P   PP    P F  S++   
Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV--PPAKKQPAFPASYIPPS 827

Query: 196 TP-PPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGG 254
            P PP+ +P              P   L+   S+   + +        P + S P  P  
Sbjct: 828 PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV- 886

Query: 255 PPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTP 314
           P       P  PP +   P    WQPS    P      P    SL    PP      P P
Sbjct: 887 PANVA---PQSPPAVKAKPK---WQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940

Query: 315 PVSIKSERLSPAPGGPG 331
           P    +       G PG
Sbjct: 941 PPPPTASPTPDKSGSPG 957



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 61/224 (27%), Positives = 79/224 (35%), Gaps = 50/224 (22%)

Query: 137 MPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKT 196
           M S +  Y +L PP      +     A S+PSP  P  P   PP    P           
Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTA-SQPSPPLPPPPPPPPPPPPPP----------P 643

Query: 197 PPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTA-----TPGPPLGSFPFL 251
           PPP  LP++   S      AG    +    S  + LQN    +      P PP+     +
Sbjct: 644 PPPPPLPSQSAPS------AGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV 697

Query: 252 PGG---PPEYGLGDPPPPP---------GLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSL 299
                 PP   +  PPPPP           L+P   AP  P     PP +       + +
Sbjct: 698 KPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV--QHI 755

Query: 300 GEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPK---TFPYP 340
            +  PPT    PP PP+        PAP  P   PK   T P P
Sbjct: 756 TQVAPPT---PPPPPPI--------PAPLPPQAPPKPLVTIPAP 788



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 59/214 (27%), Positives = 71/214 (33%), Gaps = 28/214 (13%)

Query: 135  PAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP-----------GLV 183
            P  PSP       PPP   P+      P +       P   K  P            G  
Sbjct: 929  PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAE 988

Query: 184  HP---LFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGG-LNTSRSLYSG-LQNPCST 238
            HP     S   L SK  PP    +  + + LP   A P+ G LN S     G LQ  C +
Sbjct: 989  HPEPKRPSVDSLVSKFTPPAESGSPSKET-LPPPAAPPKPGKLNLSGVNLPGVLQQGCVS 1047

Query: 239  ATP----GPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGP--PAVSSQ 292
            A      G    S    P  P +     PPP   L  PP   P   S    P    V+ Q
Sbjct: 1048 AKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQ 1107

Query: 293  PSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326
            P     +       + A PPT P    S RL+ A
Sbjct: 1108 PQQWSKMS-----VKKAPPPTRPKRNDSTRLTQA 1136


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 66/240 (27%), Positives = 79/240 (32%), Gaps = 34/240 (14%)

Query: 121  GDPALPRPRLYPAAPAMPSPDVVYG---------ALPPPGCDPSGLGEALPAQSRPSPFR 171
            G PA P P+  P  PA   P    G           PP    PS  G       + +P  
Sbjct: 952  GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011

Query: 172  PAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPT-EGRRSDLPGGLAGPRGGLNTSRSLYS 230
            PA     P G   P  +P    + TPP    P+ +G  +  P     P     T  S   
Sbjct: 1012 PAVTPPSPKG--SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069

Query: 231  GLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRG------- 283
            G   P     P PP  + P   GGP        P P G   PP   P  P  G       
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPA------TPSPKGAPMPPAATPPSPKGGLATPPHK 1123

Query: 284  ---DGPPAVSSQPSGGRSLGEEGPPTRGA--SPPTPPVSIKSERLSPAPGGPGDFPKTFP 338
                 P A    P GG +     PP +GA  +P   P S K    +P P G    P   P
Sbjct: 1124 GAPTTPAATPPSPKGGLAT----PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179



 Score = 65.9 bits (159), Expect = 6e-11
 Identities = 70/253 (27%), Positives = 83/253 (32%), Gaps = 39/253 (15%)

Query: 121  GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPF---------- 170
            G  A P P+  P  PA   P    G   P    P G     PA + PSP           
Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATP---SPKG-APTTPAATPPSPKGGLATPSPKG 1216

Query: 171  RPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYS 230
             P  P A PP     L +PS   + T P    P+       P     P     T  SL  
Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276

Query: 231  GLQNPCSTATPGPPLGSFPFLPGGP---PEYGLGDP--------------PPPPGLLQPP 273
            GL  P     P P + + P   GGP   P  G   P              PPP G   PP
Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336

Query: 274  TLAPWQPSRGDGPPAVSSQPSGGRSL--GEEGP------PTRGASPPTPPVSIKSERLSP 325
             + P  P      PA +    GG +    +EGP      P+    P   P S K     P
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396

Query: 326  APGGPGDFPKTFP 338
            +P G    P   P
Sbjct: 1397 SPKGDPTSPAVIP 1409



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 86/301 (28%), Positives = 107/301 (35%), Gaps = 83/301 (27%)

Query: 121  GDPALPRPRLYPAAPAMPSPDVVYGALPPPGC-----------DPSGLGEALPAQSRPSP 169
            G PA P P+  P  PA   P +  G   PP              P G     P +  P+P
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312

Query: 170  --FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRS 227
                P +PK G PG   P  +P      TPP +  P+      LP      +GG  T   
Sbjct: 1313 PAATPPSPK-GSPGTPPPKGAP------TPPAVTPPSPKGTPTLPATTPSSKGGPTT--- 1362

Query: 228  LYSGLQNPCSTATPGPPLGSFPFLPGGP------PEYG------LGDPPPPPGLLQPPTL 275
                   P S   P PP  + P   GGP      P+ G       GDP  P  +   P  
Sbjct: 1363 -------PSSKEGPTPPAAT-PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414

Query: 276  APWQP---------SRGD-GPPAVS----------SQPSGGRSL-GEEGPPTRGA----S 310
            AP  P         S+GD  PPAV+          S P GG +    +G PT  A    S
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474

Query: 311  PPTPPV--------SIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRLPL 362
            P  PP         S K    +PAP G    P   P       S  + +   P+ RR P+
Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP-------SSPKEVPATPSSRRDPI 1527

Query: 363  A 363
            A
Sbjct: 1528 A 1528



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 76/270 (28%), Positives = 93/270 (34%), Gaps = 33/270 (12%)

Query: 119  EGGDPALPRPRLYPAAPA--MPSPD------VVYGA-LPPPGCDPSGLGEALPAQSRPSP 169
            +G   A P P+  P  PA  +PSP        + GA  PP    PS  G       + +P
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103

Query: 170  FRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLY 229
              PAA    P G    L +P H  + T P    P+       P     P     T  S  
Sbjct: 1104 MPPAATPPSPKG---GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160

Query: 230  SGLQNP-------CSTATPGPPLGSFPF-LPGGPPEYGLGDPPPPPGLLQPPTLAPWQPS 281
             GL  P          ATP  P G      P G P      PP P G L  P+       
Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS----PKG 1216

Query: 282  RGDGPPAVSSQPSGGRSL--GEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPY 339
                P A    P GG +    +  P T  A+PP+P    K    +P P G    P   P 
Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP----KGGPATPPPKGAPTPPAATP- 1271

Query: 340  PLLLARSLAEPLR--PGPALRRLPLADGWP 367
            P L       P +  P PA+   P   G P
Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 61/221 (27%), Positives = 73/221 (33%), Gaps = 29/221 (13%)

Query: 132  PAAPAMPSPDVVYGALPPPGCDP-SGLGEALPAQSRPSP--FRPAAPKAGP--------P 180
            PA    P+P    GA  P    P S  G  LP +  P+P       PK GP        P
Sbjct: 850  PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909

Query: 181  GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240
             L     SP    + TP P  +P        P     P     T  S   G   P     
Sbjct: 910  ALSMTSSSPKKARA-TPAPKGIPAS------PSPKGAPTPPAATPPSPKGGPATPSPKWA 962

Query: 241  PGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLG 300
            P PP  + P   GGP        P P G   PP   P  P  G   P+    P G  +  
Sbjct: 963  PTPPAATPPSPKGGPAT------PSPKGAPTPPAATPPSPKGGPATPS----PKGAPTPP 1012

Query: 301  EEGPPT-RGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYP 340
               PP+ +G+   TP     S   +  P  P   P   P P
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 64/228 (28%), Positives = 78/228 (34%), Gaps = 27/228 (11%)

Query: 102  PDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEAL 161
            P  GP  P  K        GDP LP     P+    P+P  V  +  P     +      
Sbjct: 1452 PKGGPATPSSK--------GDPTLPAVTP-PSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502

Query: 162  PAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGG 221
            P      P  P    A P     P+   + L SK  P    P E     +P  +  P   
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL---IPPAMTVP--- 1556

Query: 222  LNTSRSLYSGLQNPCST-ATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQP 280
               S      +  P    ATP     S P  P   P    G P P   LL PP +    P
Sbjct: 1557 ---SPKKTPAIPTPKEAPATPSSKEASSP--PAVTPSTYKGAPSPKE-LLIPPAVTSPSP 1610

Query: 281  SRGDGPPAVS--SQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326
                 PPAV+  S   G  +   +G PT   SPP  P S+K    SPA
Sbjct: 1611 KEAPTPPAVTPPSPEKGPATPAPKGTPT---SPPVTPSSLKDSPTSPA 1655



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 56/211 (26%), Positives = 72/211 (34%), Gaps = 37/211 (17%)

Query: 125  LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVH 184
            LP P+  PA PA            P       +  + P ++R +P    APK  P     
Sbjct: 893  LPFPKEGPATPA------------PKQAPALSMTSSSPKKARATP----APKGIPA---- 932

Query: 185  PLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPP 244
               SPS   + TPP    P+       P     P     T  S   G   P     P PP
Sbjct: 933  ---SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP 989

Query: 245  LGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGP 304
              + P   GGP        P P G   PP + P  P    G PA +  P G  +     P
Sbjct: 990  AATPPSPKGGPA------TPSPKGAPTPPAVTPPSPK---GSPAATPFPKGASTPPAATP 1040

Query: 305  PTRGASPPTPPV-----SIKSERLSPAPGGP 330
            P+   SP   P+     +  +  L    GGP
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 64/229 (27%), Positives = 85/229 (37%), Gaps = 30/229 (13%)

Query: 130 LYPAAP-AMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAA--PKAGPP---GLV 183
           L P  P ++PSP     +LPP G  P    + +   S  S   P A  PK  P    G  
Sbjct: 726 LAPEIPKSVPSP-----SLPPAGTPPGT--KKVDGISHTSALAPVASSPKECPTEDSGAS 778

Query: 184 HPLFSPSHLT----SKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTA 239
               S   LT    S +P  + +  + +R     G AGP   +    S  S ++   ++ 
Sbjct: 779 ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE---ASF 835

Query: 240 TPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS-GGRS 298
            P   L SF      P       PP P G   P  + P  P     PP  +  PS     
Sbjct: 836 LPENSL-SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP 894

Query: 299 LGEEGPPTRGASPPTPPVSI-----KSERLSPAPGG--PGDFPKTFPYP 340
             +EGP T  A    P +S+     K  R +PAP G      PK  P P
Sbjct: 895 FPKEGPAT-PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 84/264 (31%), Positives = 94/264 (35%), Gaps = 36/264 (13%)

Query: 95   LDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDP 154
            L G E+ P   P  PG          G   LP P L P A   P P +   A+PPP   P
Sbjct: 902  LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPL-PGAGIPPPPPLPGAAIPPPPPLP 960

Query: 155  SG---LGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL 211
                 L   LP    P P  P  P AG P        P    +  PPP  LP  G    +
Sbjct: 961  GAGIPLPPPLPGAGIPPP--PPLPGAGIPP------PPPLPGAGIPPPPPLPGAG----I 1008

Query: 212  PGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGG-----PPEYGLGDPPPP 266
            P     P  G+     L  G   P     PG  +   P LPG      PP  G G PPPP
Sbjct: 1009 PPPPPLPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1067

Query: 267  P----GLLQPPTL-----APWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVS 317
            P    G+  PP L      P  P  G G P     P  G       PP  GA  P PP  
Sbjct: 1068 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI---PPPPPLPGAGIPPPP-P 1123

Query: 318  IKSERLSPAPGGPG-DFPKTFPYP 340
            +    + P P  PG   P   P P
Sbjct: 1124 LPGAGIPPPPPLPGAGIPPPPPLP 1147



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 87/293 (29%), Positives = 103/293 (35%), Gaps = 43/293 (14%)

Query: 92   GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151
            G G+  P   P  G   P      L G G    +P P   P A   P P +    +PPP 
Sbjct: 983  GAGIPPPPPLPGAGIPPPPP----LPGAG----IPPPPPLPGAGIPPPPPLPGAGIPPPP 1034

Query: 152  CDP-SGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSD 210
              P +G+    P      P  P  P AG P        P    +  PPP  LP  G    
Sbjct: 1035 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP------PPPLPGAGIPPPPPLPGAG---- 1084

Query: 211  LPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGG-----PPEYGLGDPPP 265
            +P     P  G+     L  G+  P     PG  +   P LPG      PP  G G PPP
Sbjct: 1085 IPPPPPLPGAGIPPPPPL-PGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1143

Query: 266  PP----GLLQPPTLA-----PWQPSRGDGPPAVSSQPSGG-------RSLGEEGPPTRGA 309
            PP    G+  PP L      P  P  G G P     P  G         +G   PP    
Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPG 1203

Query: 310  SPPTPPVSIKSERLSPAPGGPGDFPKT-FPYPLLLARSLAEPLRPGPALRRLP 361
            +   PP  +    + PAP  P   P T  P P LL  S   PL P      LP
Sbjct: 1204 AGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVS-GPPLLPQVGSSTLP 1255



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 75/236 (31%), Positives = 87/236 (36%), Gaps = 36/236 (15%)

Query: 92   GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151
            G G+  P   P  G   P      L G G    +P P   P A   P P +    +PPP 
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPP----LPGAG----IPPPPPLPGAGIPPPPPLPGAGIPPPP 1100

Query: 152  CDPSGLG----EALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGR 207
              P G+G      LP    P P  P  P AG P        P    +  PPP  LP  G 
Sbjct: 1101 PLP-GVGIPPPPPLPGAGIPPP--PPLPGAGIPP------PPPLPGAGIPPPPPLPRVG- 1150

Query: 208  RSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPG-----GPPEYGLGD 262
               +P     P  G+     L  G   P     PG  +   P LPG      PP  G G 
Sbjct: 1151 ---IPPPPPLPGAGIPPPPPL-PGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGI 1206

Query: 263  PPPPP--GLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPV 316
            PPPPP  G+  PP  AP  P  G G P     P  G  L    P    ++ PTP V
Sbjct: 1207 PPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPL---LPQVGSSTLPTPQV 1259



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 68/228 (29%), Positives = 79/228 (34%), Gaps = 35/228 (15%)

Query: 125  LPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVH 184
            +P P   P   +  S   +    PPP   P      LP+ + P P     P  G   L  
Sbjct: 855  IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQP----PPLQGTEMLPP 910

Query: 185  PLFSPSHLTSKTPPPLYLPTEG--RRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPG 242
            P   P    +  PPP  LP  G      LPG    P   L            P +   P 
Sbjct: 911  P--PPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL------------PGAAIPPP 956

Query: 243  PPLGSFPFLPGGPPEYGLGDPPPPP----GLLQPPTL-----APWQPSRGDGPPAVSSQP 293
            PPL     +P  PP  G G PPPPP    G+  PP L      P  P  G G P     P
Sbjct: 957  PPLPGAG-IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015

Query: 294  SGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPG-DFPKTFPYP 340
              G       PP  GA  P PP  +    + P P  PG   P   P P
Sbjct: 1016 GAGI---PPPPPLPGAGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLP 1059



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 52/204 (25%), Positives = 67/204 (32%), Gaps = 28/204 (13%)

Query: 161 LPAQSRPSPFRPAAPKAGPPGLVHP-----------LFSPSHLTSKTP-PPLYLPTEGRR 208
           L  Q +    + A   A PP  V P           L  PS    + P  P         
Sbjct: 217 LQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSAL 276

Query: 209 SDLPGGLAG-PR--------GGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYG 259
           SDLP  LA  PR        GGL  S +       P +  +P     +FPF   GP E  
Sbjct: 277 SDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSST--AFPFPEAGPGEEA 334

Query: 260 LGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIK 319
            G P    G     T    +    +  P  S        +GE+ P   G  P        
Sbjct: 335 AGAPVRGAG----DTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPD 390

Query: 320 SERLSPAPGGPGDFPKTF-PYPLL 342
           +   +  PG P    + F PYPL+
Sbjct: 391 APAAASLPGSPAPSQRCFKPYPLI 414



 Score = 29.3 bits (64), Expect = 5.9
 Identities = 26/101 (25%), Positives = 37/101 (36%), Gaps = 5/101 (4%)

Query: 256 PEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPP-AVSSQPSGGRSLGEEGPPTRGASPPTP 314
           P   +  PPPPP LL     +  Q   G  PP ++S++                 + P+P
Sbjct: 803 PTQSISQPPPPPSLL----WSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP 858

Query: 315 PVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGP 355
           P    +E  S  PG     P   P P +   +L     P P
Sbjct: 859 PPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQP 899


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 79/251 (31%), Positives = 91/251 (36%), Gaps = 40/251 (15%)

Query: 94  GLDGPELEPDEG-PEEPGEKFRRLAG-----------EG--GDPALPRPRLYPAAPAMPS 139
           GL GP   P  G P  PG K  R  G           +G  G P +  P   P  P +P 
Sbjct: 340 GLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPG 399

Query: 140 PDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP- 198
           P    GA+  PG  P G G  +  Q  P P        G PGL      P  L    PP 
Sbjct: 400 PMGPPGAIGFPG--PKGEGGIVGPQGPPGP-------KGEPGLQGFPGKPGFLGEVGPPG 450

Query: 199 ------PLYLPTEGRRSDLPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGS 247
                 P+    E  +  +PG     GL GP+G          GLQ P      G P G 
Sbjct: 451 MRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGD--QGLQGPPGIPGIGGPSGP 508

Query: 248 F--PFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPP 305
              P +PG   E GL  PP  PG+ +P       P    G      QP      G  GPP
Sbjct: 509 IGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPP 568

Query: 306 TRGA-SPPTPP 315
              A  PPTPP
Sbjct: 569 GPPAVMPPTPP 579



 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 79/279 (28%), Positives = 99/279 (35%), Gaps = 56/279 (20%)

Query: 86  ETLKRRGIGLDGPELEPDEGPE-EPGEKFRRLAGEGGDPALPR-----------PRLYPA 133
           E + ++G  +    L  ++GP  EPG +     G  G P LP            P+ YP 
Sbjct: 102 EAVPKKGKEIPLASLRGEQGPRGEPGPR-----GPPGPPGLPGHGIPGIKGKPGPQGYPG 156

Query: 134 A--PAMPSPDVVYGALPPPGCDPS-GLGEALPAQSRPSPFRPAAP-------KAGPPGLV 183
              P MP      GA+  PG     G    +     P P  P  P       K G PGL 
Sbjct: 157 VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLP 216

Query: 184 HPLFSPSHLTSKTPPPLYLPT--EGRRSD----LPG--GLAGPRGGLNTSRSL-YSGLQN 234
                P     + P  L  P    G + D    +PG  G+ GP G       +   G+  
Sbjct: 217 G---QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGK 273

Query: 235 PCSTATPGP--PLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ 292
           P  T  PGP  PLG     PG P E G   P   PG+  PP +        DG P     
Sbjct: 274 PGVTGFPGPQGPLGK----PGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGF 329

Query: 293 PSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPG 331
           P G    GE+G P     P  P +          PG PG
Sbjct: 330 PGG---KGEQGLPGLPGPPGLPGIG--------KPGFPG 357



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 69/248 (27%), Positives = 84/248 (33%), Gaps = 53/248 (21%)

Query: 97  GPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDV--VYGALPP---PG 151
           G E  P +G E P      L GE G    P PR  P  P +P   +  + G   P   PG
Sbjct: 100 GKEAVPKKGKEIP---LASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPG 156

Query: 152 CDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL 211
               G+   +P +        A  + G  G + P+  P       P P  LP  G+    
Sbjct: 157 VGKPGM-PGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG--PQGPPGPHGLPGIGKPGG- 212

Query: 212 PG--GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLG-SFPFLPG--GPPEYGLGDPPPP 266
           PG  G  GP+G          GL  P     P    G   P  PG  GPP  G+  PP P
Sbjct: 213 PGLPGQPGPKGDRGPK-----GLPGPQGLRGPKGDKGFGMPGAPGVKGPP--GMHGPPGP 265

Query: 267 PGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326
            GL             G G P V+  P     LG+ G P                   P 
Sbjct: 266 VGL------------PGVGKPGVTGFPGPQGPLGKPGAPGE-----------------PG 296

Query: 327 PGGPGDFP 334
           P GP   P
Sbjct: 297 PQGPIGVP 304



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 75/259 (28%), Positives = 90/259 (34%), Gaps = 58/259 (22%)

Query: 92  GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAA--PAMPSPDVVYGALPP 149
           GIG  G +  P + P  PG K     GE G P LP P   P    P  P P    G    
Sbjct: 314 GIGKPGQDGIPGQ-PGFPGGK-----GEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367

Query: 150 PGC-DPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRR 208
           PG   P G    + A     P  P  P  G PG+  P+           PP  +   G +
Sbjct: 368 PGALGPRGEKGPIGAPGIGGP--PGEP--GLPGIPGPM----------GPPGAIGFPGPK 413

Query: 209 SDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPG 268
            +  GG+ GP+G              P     PG  L  FP  PG   E G   PP   G
Sbjct: 414 GE--GGIVGPQGP-------------PGPKGEPG--LQGFPGKPGFLGEVG---PPGMRG 453

Query: 269 LLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGE---------EGPP----TRGASPPTPP 315
           L  P  + P   +   G P +   P      GE         +GPP      G S P  P
Sbjct: 454 L--PGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGP 511

Query: 316 VSIKSERLSPAPGGPGDFP 334
             I   +  P   GP  FP
Sbjct: 512 PGIPGPKGEPGLPGPPGFP 530



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 33/106 (31%), Positives = 40/106 (37%), Gaps = 17/106 (16%)

Query: 94  GLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPP-GC 152
           GL GP       P +PG       G  G P LP P   P  P  P P  V    PPP G 
Sbjct: 539 GLHGP-------PGKPGA-----LGPQGQPGLPGP---PGPPGPPGPPAVMPPTPPPQGE 583

Query: 153 DPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP 198
               +G  +     P  +     K G P    P F+ + LT+  PP
Sbjct: 584 YLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFT-AELTAPFPP 628


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 79/251 (31%), Positives = 91/251 (36%), Gaps = 40/251 (15%)

Query: 94  GLDGPELEPDEG-PEEPGEKFRRLAG-----------EG--GDPALPRPRLYPAAPAMPS 139
           GL GP   P  G P  PG K  R  G           +G  G P +  P   P  P +P 
Sbjct: 340 GLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPG 399

Query: 140 PDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP- 198
           P    GA+  PG  P G G  +  Q  P P        G PGL      P  L    PP 
Sbjct: 400 PMGPPGAIGFPG--PKGEGGIVGPQGPPGP-------KGEPGLQGFPGKPGFLGEVGPPG 450

Query: 199 ------PLYLPTEGRRSDLPG-----GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGS 247
                 P+    E  +  +PG     GL GP+G          GLQ P      G P G 
Sbjct: 451 MRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGD--QGLQGPPGIPGIGGPSGP 508

Query: 248 F--PFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPP 305
              P +PG   E GL  PP  PG+ +P       P    G      QP      G  GPP
Sbjct: 509 IGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPP 568

Query: 306 TRGA-SPPTPP 315
              A  PPTPP
Sbjct: 569 GPPAVMPPTPP 579



 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 79/279 (28%), Positives = 99/279 (35%), Gaps = 56/279 (20%)

Query: 86  ETLKRRGIGLDGPELEPDEGPE-EPGEKFRRLAGEGGDPALPR-----------PRLYPA 133
           E + ++G  +    L  ++GP  EPG +     G  G P LP            P+ YP 
Sbjct: 102 EAVPKKGKEIPLASLRGEQGPRGEPGPR-----GPPGPPGLPGHGIPGIKGKPGPQGYPG 156

Query: 134 A--PAMPSPDVVYGALPPPGCDPS-GLGEALPAQSRPSPFRPAAP-------KAGPPGLV 183
              P MP      GA+  PG     G    +     P P  P  P       K G PGL 
Sbjct: 157 VGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLP 216

Query: 184 HPLFSPSHLTSKTPPPLYLPT--EGRRSD----LPG--GLAGPRGGLNTSRSL-YSGLQN 234
                P     + P  L  P    G + D    +PG  G+ GP G       +   G+  
Sbjct: 217 G---QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGK 273

Query: 235 PCSTATPGP--PLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQ 292
           P  T  PGP  PLG     PG P E G   P   PG+  PP +        DG P     
Sbjct: 274 PGVTGFPGPQGPLGK----PGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGF 329

Query: 293 PSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPG 331
           P G    GE+G P     P  P +          PG PG
Sbjct: 330 PGG---KGEQGLPGLPGPPGLPGIG--------KPGFPG 357



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 69/248 (27%), Positives = 84/248 (33%), Gaps = 53/248 (21%)

Query: 97  GPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDV--VYGALPP---PG 151
           G E  P +G E P      L GE G    P PR  P  P +P   +  + G   P   PG
Sbjct: 100 GKEAVPKKGKEIP---LASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPG 156

Query: 152 CDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL 211
               G+   +P +        A  + G  G + P+  P       P P  LP  G+    
Sbjct: 157 VGKPGM-PGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPG--PQGPPGPHGLPGIGKPGG- 212

Query: 212 PG--GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLG-SFPFLPG--GPPEYGLGDPPPP 266
           PG  G  GP+G          GL  P     P    G   P  PG  GPP  G+  PP P
Sbjct: 213 PGLPGQPGPKGDRGPK-----GLPGPQGLRGPKGDKGFGMPGAPGVKGPP--GMHGPPGP 265

Query: 267 PGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPA 326
            GL             G G P V+  P     LG+ G P                   P 
Sbjct: 266 VGL------------PGVGKPGVTGFPGPQGPLGKPGAPGE-----------------PG 296

Query: 327 PGGPGDFP 334
           P GP   P
Sbjct: 297 PQGPIGVP 304



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 75/259 (28%), Positives = 90/259 (34%), Gaps = 58/259 (22%)

Query: 92  GIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAA--PAMPSPDVVYGALPP 149
           GIG  G +  P + P  PG K     GE G P LP P   P    P  P P    G    
Sbjct: 314 GIGKPGQDGIPGQ-PGFPGGK-----GEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGV 367

Query: 150 PGC-DPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRR 208
           PG   P G    + A     P  P  P  G PG+  P+           PP  +   G +
Sbjct: 368 PGALGPRGEKGPIGAPGIGGP--PGEP--GLPGIPGPM----------GPPGAIGFPGPK 413

Query: 209 SDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPG 268
            +  GG+ GP+G              P     PG  L  FP  PG   E G   PP   G
Sbjct: 414 GE--GGIVGPQGP-------------PGPKGEPG--LQGFPGKPGFLGEVG---PPGMRG 453

Query: 269 LLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGE---------EGPP----TRGASPPTPP 315
           L  P  + P   +   G P +   P      GE         +GPP      G S P  P
Sbjct: 454 L--PGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGP 511

Query: 316 VSIKSERLSPAPGGPGDFP 334
             I   +  P   GP  FP
Sbjct: 512 PGIPGPKGEPGLPGPPGFP 530



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 33/106 (31%), Positives = 40/106 (37%), Gaps = 17/106 (16%)

Query: 94  GLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPP-GC 152
           GL GP       P +PG       G  G P LP P   P  P  P P  V    PPP G 
Sbjct: 539 GLHGP-------PGKPGA-----LGPQGQPGLPGP---PGPPGPPGPPAVMPPTPPPQGE 583

Query: 153 DPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPP 198
               +G  +     P  +     K G P    P F+ + LT+  PP
Sbjct: 584 YLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFT-AELTAPFPP 628


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 76/260 (29%), Positives = 86/260 (33%), Gaps = 41/260 (15%)

Query: 108  EPGEK-FRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCD--PSGLGEALPAQ 164
            EPGE   R   G  GDP LP     P     P      G    PG D  P   G A    
Sbjct: 1258 EPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRA---- 1313

Query: 165  SRPSPFRPAAPKA-GPPGLVHPLFSPSHLTSKTP------PPLYLPTEG-----RRSDL- 211
               +P  P AP   G PGL  P   P     + P      P   +  EG     R+ D  
Sbjct: 1314 --GNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPG 1371

Query: 212  PGGLAGPRGGLNT----------SRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLG 261
            P G  GPRG L              ++     +      PGP  G     PG P   GL 
Sbjct: 1372 PSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIA--PGEPGLPGLP 1429

Query: 262  DPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPP-------TRGASPPTP 314
              P P G + PP     +    DG P +  QP      G  GPP        RG   P  
Sbjct: 1430 GSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLG 1489

Query: 315  PVSIKSERLSPAPGGPGDFP 334
                K ER  P P G    P
Sbjct: 1490 EAGEKGERGPPGPAGSRGLP 1509



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 69/240 (28%), Positives = 89/240 (37%), Gaps = 34/240 (14%)

Query: 118  GEGGDPALPRPRLYPAAPAMPSPDVVYGALPP--PGCDPSGLGEALPAQSRPSPFRPAAP 175
            G  G+P  P       +P +P P    G   P  P  +P   G+ +  +    P R   P
Sbjct: 1311 GRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDP 1370

Query: 176  -KAGPPGLVHPLFSPSHLTSKTPPPLY-LPTEGRRSDL-PGGLAGP-RGGLNTSRSLYSG 231
              +GPPG   PL  P     + PP L     +G + D    G  GP  GG+        G
Sbjct: 1371 GPSGPPGPRGPLGDPG---PRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPG 1427

Query: 232  LQ-NPCSTATPGPP---------LGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPS 281
            L  +P      GPP             P LPG P   G   P  PPG + P     +   
Sbjct: 1428 LPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGP 1487

Query: 282  RGD-------GPPAVSSQPSGGRSL-GEEGPP-TRGASPPTPPVSIKSERLSPAPGGPGD 332
             G+       GPP     P+G R L G  G P  +G   P  P   + E+    PG PGD
Sbjct: 1488 LGEAGEKGERGPPG----PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEK--GEPGRPGD 1541



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 93/331 (28%), Positives = 107/331 (32%), Gaps = 100/331 (30%)

Query: 94   GLDGPELEPDE----GPE-EPGEKFRRLAGEG-------GDPAL------------PRPR 129
            GL GP  +P E    GP+ EPG   + + GEG       GDP              P PR
Sbjct: 1329 GLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPR 1388

Query: 130  LYPAAP--AMPSPDVVYGALPPPGCDPSGLGEALPA----QSRPSPFRPAAPKA------ 177
              P  P  AM       G   PPG    G+    P        P P  P  P        
Sbjct: 1389 GPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG 1448

Query: 178  ----GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRG-----GLNTSRSL 228
                G PGL     SP     + PP    P   R    P G AG +G     G   SR L
Sbjct: 1449 DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGL 1508

Query: 229  YSGLQNPCSTATPGPPLGSF-------PFLPGGP---------PEYGLGDPPP------- 265
                  P +    GPP  +        P  PG P         P+   GD  P       
Sbjct: 1509 PGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGAT 1568

Query: 266  -------PPGLLQPPTLAPWQPSRGD----------GPPAVSSQPSGGRSLGEEGPPTRG 308
                   PPGL+ P    P +   GD          GPP  S  P      GE+G P R 
Sbjct: 1569 GVQGERGPPGLVLPGDPGP-KGDPGDRGPIGLTGRAGPPGDSGPP------GEKGDPGRP 1621

Query: 309  ASP-PTPP------VSIKSERLSPA-PGGPG 331
              P P  P      V  K +   P  PG PG
Sbjct: 1622 GPPGPVGPRGRDGEVGEKGDEGPPGDPGLPG 1652



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 66/209 (31%), Positives = 80/209 (38%), Gaps = 29/209 (13%)

Query: 151  GCDPSGLGEALPAQSRPSPFRPAAPKAGPP------GLVHPLFSPSHLTSKTPPP--LYL 202
            G DP  L    P       F   A   GP       GL   L   S  T   P P  +Y 
Sbjct: 1194 GADPEQLRRLAPGMDSVQTF--FAVDDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYC 1251

Query: 203  PTEGRRSDLPG-----GLAGPRG--GLNTSRSLYSGLQNPCSTATPGPPLGSFPFL---P 252
            P +G++ + PG     G  GP G  GL   R+   G Q P  +AT     G FP     P
Sbjct: 1252 P-KGQKGE-PGEMGLRGQVGPPGDPGL-PGRTGAPGPQGPPGSATAKGERG-FPGADGRP 1307

Query: 253  GGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD-GPPAVSSQPSG-GRSLGEEGP--PTRG 308
            G P   G    P  PGL   P L   +   G+ GP     +P   G+ +G EGP  P R 
Sbjct: 1308 GSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRK 1367

Query: 309  ASP-PTPPVSIKSERLSPAPGGPGDFPKT 336
              P P+ P   +     P P GP   P T
Sbjct: 1368 GDPGPSGPPGPRGPLGDPGPRGPPGLPGT 1396



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 77/262 (29%), Positives = 91/262 (34%), Gaps = 40/262 (15%)

Query: 94   GLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCD 153
            GL G + EP    ++  +  R + G  GD   P PR     P +P    + G    PG  
Sbjct: 2111 GLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQ 2170

Query: 154  -PSGLGEALPAQSRPSPFRPAAP-KAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDL 211
             P G    +     P P  P AP  AGP G   P           PP   L        L
Sbjct: 2171 GPRGPPGPVGGHGDPGP--PGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGL 2228

Query: 212  PG-----GLAGPRGGLNTSRSLYSGLQNPC-STATPGPP-----------LGSFPFLPGG 254
            PG     GL GP+G          GL      T  PG P            GS P +PG 
Sbjct: 2229 PGPPGPSGLVGPQGS--------PGLPGQVGETGKPGAPGRDGASGKDGDRGS-PGVPGS 2279

Query: 255  PPEYGLGDPPPPPGLLQPPTLAPWQPSRG-DGPPAVSSQPSG--GRSLGEEGPPTRGASP 311
            P   G   P   PG    PT AP Q   G  G       P G  G  +GE  P  +G   
Sbjct: 2280 PGLPGPVGPKGEPG----PTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE--PGAKGDRG 2333

Query: 312  PTPPVSIKSER-LSPAPGGPGD 332
               P   K E   +  PG PG+
Sbjct: 2334 LPGPRGEKGEAGRAGEPGDPGE 2355



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 79/298 (26%), Positives = 100/298 (33%), Gaps = 62/298 (20%)

Query: 94   GLDGPELEPDEG-PEEPG----EKFRRLAGEGGDPALPRPRLYPAAP-AMPSPDVVYGAL 147
            GL GP   P +G P  PG    +  R   G  G+  LP  R     P ++P+ D +   L
Sbjct: 1890 GLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRL---L 1946

Query: 148  PPPGCDPSGLGEALPAQSR------PSPFRPAAPKA-----GPPGLVHPLFSPSH----- 191
               G   S L E +           P P R   PK      GPPG   P+  P       
Sbjct: 1947 ETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKG 2006

Query: 192  --------------LTSKTPP-PLYLPTEGRRSDLPG-----------GLAGPRG--GLN 223
                          L  + PP P  L  E  +  +PG           G  G RG  G  
Sbjct: 2007 DRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEK 2066

Query: 224  TSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLL----QPPTLAPWQ 279
              R        P    TPGPP    P +    P  GL     PPGL     +P +     
Sbjct: 2067 GERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQG 2126

Query: 280  PSRGDGPPAVSSQPSGGRSLGEEG----PPTRGASPPTPPVSIKSERLSPAP-GGPGD 332
            P    G P +          G++G    P  RG + P     ++  R  P P GG GD
Sbjct: 2127 PKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGD 2184



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 80/305 (26%), Positives = 99/305 (32%), Gaps = 84/305 (27%)

Query: 94   GLDGPELEPDEGPEEPGEK----FRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPP 149
            G  GP+ +P   P  PGE+    FR   G  GDP +              P    G   P
Sbjct: 1728 GPRGPKGDPGL-PGAPGERGIEGFRGPPGPQGDPGVR------------GPAGEKGDRGP 1774

Query: 150  PGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGL--VHPLFSPSHLTSKTPPPLYLPTEGR 207
            PG D     +  P  + PS    AA KAG PG   +  L     L   + PP  LP +  
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP-GLPGKPG 1833

Query: 208  RSDLPG-----------------------------GLAGPRGGLNTSRSLYSGLQNPCST 238
                PG                             G  GP+G       L  G Q P   
Sbjct: 1834 EDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGIL--GPQGPPGL 1891

Query: 239  ATP-GPPLGSFPFLPGG------------------PPEYGL-GDPPPPPG---LLQP--- 272
              P GPP   FP +PGG                  P E GL G+P   P    LL+    
Sbjct: 1892 PGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGI 1951

Query: 273  ------PTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTP-PVSIKSERLSP 325
                    +  W  S G   P    +       GE+GPP +      P    +K +R  P
Sbjct: 1952 KASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDP 2011

Query: 326  APGGP 330
             P GP
Sbjct: 2012 GPQGP 2016



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 66/244 (27%), Positives = 78/244 (31%), Gaps = 66/244 (27%)

Query: 94   GLDGPELEPDEGPE--EPGEKFRRLAGEGGDPALPRPRLY--------PAAPAMPSPDVV 143
            GL GP  E  E     EPG+      GE G    P P+ +        P +P  P P  V
Sbjct: 2333 GLPGPRGEKGEAGRAGEPGDP-----GEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGV 2387

Query: 144  YGALPPPGCDPSGLGEALPAQS---------RPSPFRPAAPKAGPPGLVHPLFSPSHLTS 194
             G L  PG   +      P Q+          PS  R  A   G  G+  PL  P    S
Sbjct: 2388 KGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGS 2447

Query: 195  KTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGG 254
              PP      +G + D   GL GPRG                               PG 
Sbjct: 2448 VGPPGA-SGLKGDKGDPGVGLPGPRGERGE---------------------------PGI 2479

Query: 255  PPEYGLGDPPPPPGLLQPPTLAPWQPSRGD----------GPPAVSSQPSGGR----SLG 300
              E G      P GL  PP     +  +GD          G  AV   P G R     +G
Sbjct: 2480 RGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMG 2539

Query: 301  EEGP 304
            E GP
Sbjct: 2540 ERGP 2543



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 79/305 (25%), Positives = 94/305 (30%), Gaps = 114/305 (37%)

Query: 106  PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEA----L 161
            P E G   R L G  G   LP P         P P  + G    PG  P  +GE      
Sbjct: 2209 PGETGPPGRGLTGPTGAVGLPGP---------PGPSGLVGPQGSPGL-PGQVGETGKPGA 2258

Query: 162  PAQS--------RPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPG 213
            P +         R SP  P +P  G PG V P   P    +     + LP        PG
Sbjct: 2259 PGRDGASGKDGDRGSPGVPGSP--GLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPG 2316

Query: 214  GLAG----------------PRGGLNTSRSLYS----------------------GLQNP 235
            GLAG                PRG    +                           G+  P
Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP 2376

Query: 236  CSTATPGPP-----LGSFPFLPGGPP---------------------EYGLGDPPP---- 265
             S   PGPP     LG  P LPG P                      E GL  PP     
Sbjct: 2377 GSPGPPGPPGVKGDLG-LPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI 2435

Query: 266  --------PPGLLQPPTLAPWQPSRGD------GPPAVSSQP----SGGRSLGEEGPPTR 307
                    PPG + PP  +  +  +GD      GP     +P      GR  G+EGP  R
Sbjct: 2436 PGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRP-GQEGP--R 2492

Query: 308  GASPP 312
            G + P
Sbjct: 2493 GLTGP 2497



 Score = 36.2 bits (82), Expect = 0.048
 Identities = 74/270 (27%), Positives = 92/270 (34%), Gaps = 63/270 (23%)

Query: 93   IGLDGPE-LEPDEGPE-------------EPGEK-------FRRLAGEGGDPALPRPRLY 131
            +G  GP  L+ D+GP              EPG+K        R L G  G P        
Sbjct: 2538 MGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAG---I 2594

Query: 132  PAAPAMPSPDVVYGALPPPG----CDPSGL-GE-ALPAQSRPSPFRPAAPKAGPPGLVHP 185
            P  P  P  D V G     G      P GL GE  +         +    +AGPPG    
Sbjct: 2595 PGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGL 2654

Query: 186  LFSPSHLTSKTPPPLYLPTEGRRSDLPG--GLAGPRG--GLNTSRSLYSGLQNPCSTATP 241
                  +     P         +S  PG  GL GP+G  G +                TP
Sbjct: 2655 AGHKGEMGEPGVPG--------QSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTP 2706

Query: 242  GPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGD-GPPAVSSQPSGGRSLG 300
            G  +G F   PG     G   PP PPG + P      Q  +G+ GPP       G R +G
Sbjct: 2707 G--IGGF---PGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPP-------GERVVG 2754

Query: 301  EEGPPTRGASPPTPPVSIKSERLSPAPGGP 330
              G P  GA         + E+  P P GP
Sbjct: 2755 APGVP--GAP------GERGEQGRPGPAGP 2776


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 83/251 (33%), Positives = 94/251 (37%), Gaps = 53/251 (21%)

Query: 94  GLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCD 153
           GL G   EP E  E PGE+  +  G GG P LP     P     P P    G   PPG  
Sbjct: 334 GLLGDRGEPGEDGE-PGEQGPQ--GLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGV- 389

Query: 154 PSGLGEALPAQSRPSPFRPAA---PKA-GPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRS 209
           P   G+  P+     P  P     P A GPPG   P   P   T +   P      G++ 
Sbjct: 390 PGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPG-FTGRPGGPGVAGALGQKG 448

Query: 210 DL--PG--GLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPP 265
           DL  PG  GL GP G          GLQ P   A P  P G    LPG   E GL  PP 
Sbjct: 449 DLGLPGQPGLRGPSG--------IPGLQGP---AGPIGPQG----LPGLKGEPGLPGPPG 493

Query: 266 PPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSP 325
                +P T  P  P    G P ++  P         GPP     PP P           
Sbjct: 494 EGRAGEPGTAGPTGPPGVPGSPGITGPP---------GPP----GPPGP----------- 529

Query: 326 APGGPGDFPKT 336
            PG PG F +T
Sbjct: 530 -PGAPGAFDET 539



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 83/258 (32%), Positives = 96/258 (37%), Gaps = 45/258 (17%)

Query: 92  GIGLDGPELEPDEG-----PEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGA 146
           G+G  G    P +G     P  PG       G  G P  P  +     P +P P    GA
Sbjct: 209 GVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGA 268

Query: 147 L---PPPGCDPSGLGEA--LPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLY 201
           +    PPG D  G+  A  LP    PS  +      GPPGL+ P       T    P L 
Sbjct: 269 VGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGP-------TGYGMPGLP 321

Query: 202 LPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPG--GPP--- 256
            P   R      GL G RG          G Q P     P P L     LPG  GPP   
Sbjct: 322 GPKGDRGPAGVPGLLGDRG--EPGEDGEPGEQGPQGLGGP-PGLPGSAGLPGRRGPPGPK 378

Query: 257 -EYGLGDPPPPPGLLQPPTLAPWQPSRGD-GPPAVSSQPSGGRSLGEEGPPTRGASPPTP 314
            E G G PP  PG+            RGD GP  ++ +P      GE G P  GA  P  
Sbjct: 379 GEAGPGGPPGVPGI------------RGDQGPSGLAGKPG---VPGERGLP--GAHGPPG 421

Query: 315 PVSIKSE-RLSPAPGGPG 331
           P   K E   +  PGGPG
Sbjct: 422 PTGPKGEPGFTGRPGGPG 439



 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 82/279 (29%), Positives = 93/279 (33%), Gaps = 57/279 (20%)

Query: 116 LAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAP 175
           L GE G P  P PR  P  P  P           PG    GL    P  + P  F     
Sbjct: 75  LKGEPGPPGKPGPRGPPGPPGFPG---------KPGMGKPGL-HGQPGPAGPPGFSRMG- 123

Query: 176 KAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNP 235
           KAGPPGL   +  P     +  P +      R    P GL GP G     +    G+  P
Sbjct: 124 KAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGP 183

Query: 236 CS-------TATPGPP----------LGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPW 278
                       PGPP          +G  P LPG P   G G  P PPGL  P      
Sbjct: 184 PGFQGEPGPQGEPGPPGDRGLKGDNGVGQ-PGLPGAP---GQGGAPGPPGLPGP------ 233

Query: 279 QPSRGDGPPAVSSQPSGGRSLGEEGPP----TRG----ASPPTPP----VSIKSERLSPA 326
               G G P +   P      GE GPP     RG      P  PP    V +      P 
Sbjct: 234 ---AGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPG 290

Query: 327 PGGP----GDFPKTFPYPLLLARSLAEPLRPGPALRRLP 361
           P GP    G+     P  L+       P  PGP   R P
Sbjct: 291 PQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGP 329



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 75/238 (31%), Positives = 86/238 (36%), Gaps = 34/238 (14%)

Query: 151 GCDP---SGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGR 207
           GC P   SG G    A   P  +     K GP G   P         + P PL LP + +
Sbjct: 21  GCGPRASSGGGAGGAAGYAPVKYIQPMQK-GPVG--PPFREGKGQYLEMPLPL-LPMDLK 76

Query: 208 RSDLPGGLAGPRGGLNTSRSLYS-GLQNPCSTATPGP--PLGSFPFLPGGPPEY-GLGDP 263
               P G  GPRG           G+  P     PGP  P G       GPP   G   P
Sbjct: 77  GEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGP 136

Query: 264 PPPPGLLQPPTLAPWQPSRG-DGPPAVSSQPSG----GR--SLGEEGPPTRGASP----- 311
           P  PGL   P +   Q  RG  GPP +   PSG    G+  + G  GPP     P     
Sbjct: 137 PGQPGLRGEPGIRGDQGLRGPPGPPGLPG-PSGITIPGKPGAQGVPGPPGFQGEPGPQGE 195

Query: 312 PTPP--VSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPALRRLPLADGWP 367
           P PP    +K +     PG PG  P     P         P  PGPA    P  DG P
Sbjct: 196 PGPPGDRGLKGDNGVGQPGLPG-APGQGGAP-------GPPGLPGPAGLGKPGLDGLP 245



 Score = 28.9 bits (63), Expect = 7.7
 Identities = 43/146 (29%), Positives = 53/146 (36%), Gaps = 17/146 (11%)

Query: 94  GLDGPELEPDEGPEEPGEKFRRLAGEGGD------PALPRPRLYPA--APAMP-SPDVVY 144
           G  GP+ EP       G       G+ GD      P L  P   P    PA P  P  + 
Sbjct: 421 GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP 480

Query: 145 GALPPPGCD-PSGLGEA-LPAQSRPS--PFRPAAP----KAGPPGLVHPLFSPSHLTSKT 196
           G    PG   P G G A  P  + P+  P  P +P      GPPG   P  +P       
Sbjct: 481 GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETG 540

Query: 197 PPPLYLPTEGRRSDLPGGLAGPRGGL 222
              L+LP  G    + G    P+ GL
Sbjct: 541 IAGLHLPNGGVEGAVLGKGGKPQFGL 566


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 75/246 (30%), Positives = 92/246 (37%), Gaps = 54/246 (21%)

Query: 131 YPAAP-----AMPSPDVVYGALPPPGCDPS-------GLGEALPAQSR---PSPFRPAAP 175
           YP  P     + PSP      LPPP  + S       G G A P +S    PS   PA P
Sbjct: 246 YPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPP 305

Query: 176 KAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNP 235
              PPG   P F+P       PPP+             G+  P   +        G  +P
Sbjct: 306 LGSPPG-PKPGFAPPPAPPPPPPPMI------------GIPPPPPPV--------GFGSP 344

Query: 236 CSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSG 295
            +   P PP  SFP      P++    PPPPP     PTL          PP   SQP+G
Sbjct: 345 GTPPPPSPP--SFP----PHPDFAAPPPPPPPPAADYPTL----------PPPPLSQPTG 388

Query: 296 GRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARS-LAEPLRPG 354
           G       PP  G  PP P      +   P P      PK+    +  ARS L   +R G
Sbjct: 389 GAPPPPPPPPPPG-PPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQG 447

Query: 355 PALRRL 360
             LRR+
Sbjct: 448 FQLRRV 453



 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 56/200 (28%), Positives = 67/200 (33%), Gaps = 64/200 (32%)

Query: 90  RRGIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPP 149
           +RG GL GP+      P  P       A   G P  P+P   P     P P  + G  PP
Sbjct: 281 QRGSGLAGPKRSSVVSPSHPPP-----APPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPP 335

Query: 150 PGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRS 209
           P   P G G        P    P +P + PP   HP F      +  PPP   P     +
Sbjct: 336 P--PPVGFGS-------PGTPPPPSPPSFPP---HPDF------AAPPPPPPPPAADYPT 377

Query: 210 DLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGL 269
             P  L+ P GG                 A P PP                  PPPPPG 
Sbjct: 378 LPPPPLSQPTGG-----------------APPPPP------------------PPPPPGP 402

Query: 270 LQPPTLAPWQPSRGDGPPAV 289
             PP       +  DG PA+
Sbjct: 403 PPPPF------TGADGQPAI 416



 Score = 37.4 bits (85), Expect = 0.022
 Identities = 35/102 (34%), Positives = 37/102 (36%), Gaps = 11/102 (10%)

Query: 118 GEGGDPALPRPRLYP-----AAPAMPSPDVV--YGALPPPGCDPSGLGEALPAQSRPSPF 170
           G  G P  P P  +P     AAP  P P     Y  LPPP       G   P    P P 
Sbjct: 342 GSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPG 401

Query: 171 RPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLP-TEGRRSDL 211
            P  P  G  G   P   P  L+  T P   LP     RSDL
Sbjct: 402 PPPPPFTGADG--QPAIPPP-LSDTTKPKSSLPAVSDARSDL 440


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 70/234 (29%), Positives = 87/234 (37%), Gaps = 35/234 (14%)

Query: 126 PRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSP-FRPAAPKAGPPGL-V 183
           PRP L  + P  P   +    +PP G  PSG     P    P+P   P AP   PP   V
Sbjct: 243 PRPPLPESLPPPPPGGLPLPPMPPTGPAPSG-PPGPPQLPPPAPGVHPPAPVVHPPASGV 301

Query: 184 HP----LFSPSHLTSKTPPPLYLPTEGRRSDLPG------GLAGPRGGLNTSRSLYSGLQ 233
           HP    +  P+       P ++ PT G     PG      G+  P  G++       G+ 
Sbjct: 302 HPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPA---PGVH 358

Query: 234 NPCSTATPGPPLGSFPFLPGGPPEYGLGDP------PPPPGL-LQPPTLAPWQPSRGDGP 286
            P     P P  G  P  PG  P      P      PP PG+  Q P + P  P      
Sbjct: 359 PPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSA 418

Query: 287 PAVSSQPSGGRSLGEEGPPTRGASPPTP-PVSIKSERLSPAPG-GPGDFPKTFP 338
           P V  QP G        P   G  PPTP P  ++     P P  GPG+ P   P
Sbjct: 419 PGVHPQPPGVH------PSNPGVHPPTPMPPMLR----PPLPSEGPGNIPPPPP 462



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 74/259 (28%), Positives = 92/259 (35%), Gaps = 45/259 (17%)

Query: 132 PAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSH 191
           PA P++P+        PPP      L   LP   RP P   + P   P GL  P   P+ 
Sbjct: 218 PAPPSLPAGPPGVKRPPPP------LMNGLPP--RP-PLPESLPPPPPGGLPLPPMPPTG 268

Query: 192 LTSKTPP-PLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPF 250
                PP P  LP        P  +  P           SG+  P     P  P G  P 
Sbjct: 269 PAPSGPPGPPQLPPPAPGVHPPAPVVHPPA---------SGVHPPAPGVHPPAP-GVHPP 318

Query: 251 LPG-GPPEYGLGDP-----PPPPGLLQPPTLAPWQPSRGDGPPA--VSSQPSGGRSLGEE 302
            PG  PP  G+  P     PP PG+  PP      P+ G  PPA  V   PS G      
Sbjct: 319 APGVHPPTSGVHPPAPGVHPPAPGV-HPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAP 377

Query: 303 G---------PPTRGASPPTPPVSIKSERLSPAPGG-----PGDFPKTFPYPLLLARSLA 348
           G         P   G  PP P +  ++  + P P G     PG  P+  P  +  +    
Sbjct: 378 GVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQ--PPGVHPSNPGV 435

Query: 349 EPLRPGPALRRLPLADGWP 367
            P  P P + R PL    P
Sbjct: 436 HPPTPMPPMLRPPLPSEGP 454



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 23/71 (32%), Positives = 27/71 (38%), Gaps = 3/71 (4%)

Query: 286 PPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLAR 345
           PPA  S P+G   +    PP     PP PP+    E L P P G    P   P     + 
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPL---PESLPPPPPGGLPLPPMPPTGPAPSG 273

Query: 346 SLAEPLRPGPA 356
               P  P PA
Sbjct: 274 PPGPPQLPPPA 284


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 79/281 (28%), Positives = 95/281 (33%), Gaps = 58/281 (20%)

Query: 92  GIGLDGP-ELEPDEGPEEPGEKFRRLAGEGGD-PALPRPRLYPAAPAMPSPDVVYGALPP 149
           G G   P E  P   PE P     R  G G   P  P PR  P  PA P+P       PP
Sbjct: 72  GAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRR-PLVPAGPAPPAAKLRPPP 130

Query: 150 PG----CDPSGLGEALPAQSRPSPFRPAAP--------KAGP------------------ 179
            G    C P     A+ A   P+P  PA P        +AGP                  
Sbjct: 131 EGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA 190

Query: 180 -PGLVHPLFSPSHLTSK---TPPPLYLPTEGRRSDLPGGLAGPRG-GLNTSRSLYSGLQN 234
            PG    L   + L +      P + L   G  + LP  L  P   G       + G   
Sbjct: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLP--LPKPAAPGTVIQTPPFVGAAA 248

Query: 235 PCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQ--------PPTLAPWQP------ 280
           P + A P PP    P  P   P      PPP P  L         PPT AP  P      
Sbjct: 249 PPAPAAPSPPAAPAPAAPAAAPP----PPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQ 304

Query: 281 SRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSE 321
           + G    A +  P+ G   G  G P  GA+   P   +K+E
Sbjct: 305 NGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAE 345



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 43/162 (26%), Positives = 50/162 (30%), Gaps = 50/162 (30%)

Query: 172 PAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSG 231
           PAAP  G PG            +  PPP              G A P GG          
Sbjct: 75  PAAPAEGAPG-----------AAPEPPP-------------AGRARPGGG---------- 100

Query: 232 LQNPCSTATPGPPLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGP---PA 288
                    PGPP    P +P GP        PPP G        P   +   GP   PA
Sbjct: 101 -----GPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPA 155

Query: 289 VSSQPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGP 330
             ++P+G  +L     P  G  P   P         P PG P
Sbjct: 156 GPAKPAGPAALAARAGPGPGPGPGPGP--------GPGPGKP 189



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 56/216 (25%), Positives = 67/216 (31%), Gaps = 59/216 (27%)

Query: 121 GDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPP 180
           G  A P P   P+ PA P+P     A PPP   P+ L       +RP P  PA P    P
Sbjct: 245 GAAAPPAPAA-PSPPAAPAPAAPAAAPPPPPPAPATL-------ARP-PGHPAGPPTAAP 295

Query: 181 GLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTAT 240
            +              PPP             GG AG                     A 
Sbjct: 296 AV--------------PPPAAAQN--------GGSAG---------------------AA 312

Query: 241 PGP-PLGSFPFLPGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGGRSL 299
           P P P    P    G P  G     P PG+         Q +        +S P+   + 
Sbjct: 313 PAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372

Query: 300 GEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPK 335
              GP  +GA P    V        PAPG P   PK
Sbjct: 373 MVIGPTMQGALPSPAAVP------PPAPGTPTGLPK 402



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 40/141 (28%), Positives = 48/141 (34%), Gaps = 36/141 (25%)

Query: 242 GPPLGSFPFLPGGPPEYGLGD--PPPPPGLLQPPTLAPWQPS----------RGDGPPAV 289
           G P G+    P  P E   G    PPP G  +P    P +P            G  PPA 
Sbjct: 65  GSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAA 124

Query: 290 SSQPSGGRSLGE-----------EGPPTRGASP--PTPPVSIKSERLSPAPG-GPGDFPK 335
             +P    S G             GP    A P  P  P ++ + R  P PG GPG  P 
Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL-AARAGPGPGPGPGPGPG 183

Query: 336 TFPYPLLLARSLAEPLRPGPA 356
             P          +P  PG A
Sbjct: 184 PGP---------GKPAGPGAA 195


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 73/245 (29%), Positives = 85/245 (34%), Gaps = 34/245 (13%)

Query: 124 ALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLV 183
           ALPR R   A+P   S    +G  P PG  P G   +      P+  RP  P+ GPP   
Sbjct: 417 ALPRQRQRDASPGRGS----HGQTPSPGALPLGRQTSQQPAGPPAQQRPP-PQGGPP--- 468

Query: 184 HPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSR--SLYSGLQNPCSTATP 241
                P     +  PPL      +      GL  P G     R  S  S  Q P S A P
Sbjct: 469 ----QPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP 524

Query: 242 ---GPPLGSFPFL--PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGG 296
              G    S P    PG PP       P P     PP         G  PP  S  P GG
Sbjct: 525 PTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGG 584

Query: 297 RSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPA 356
           +    +GPP +   P  P     + + S A   P   P T   P         P  PGPA
Sbjct: 585 QQ--RQGPPQKPPGPAGP-----TRQASQAGPVPRTGPPTTQQP--------RPSGPGPA 629

Query: 357 LRRLP 361
            R  P
Sbjct: 630 GRPKP 634



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 5/43 (11%)

Query: 263 PPPPPGLLQP-----PTLAPWQPSRGDGPPAVSSQPSGGRSLG 300
           PPPPPG   P     P  A  + S G  P A  + PS G S G
Sbjct: 31  PPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 73/245 (29%), Positives = 85/245 (34%), Gaps = 34/245 (13%)

Query: 124 ALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLV 183
           ALPR R   A+P   S    +G  P PG  P G   +      P+  RP  P+ GPP   
Sbjct: 417 ALPRQRQRDASPGRGS----HGQTPSPGALPLGRQTSQQPAGPPAQQRPP-PQGGPP--- 468

Query: 184 HPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSR--SLYSGLQNPCSTATP 241
                P     +  PPL      +      GL  P G     R  S  S  Q P S A P
Sbjct: 469 ----QPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP 524

Query: 242 ---GPPLGSFPFL--PGGPPEYGLGDPPPPPGLLQPPTLAPWQPSRGDGPPAVSSQPSGG 296
              G    S P    PG PP       P P     PP         G  PP  S  P GG
Sbjct: 525 PTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGG 584

Query: 297 RSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPKTFPYPLLLARSLAEPLRPGPA 356
           +    +GPP +   P  P     + + S A   P   P T   P         P  PGPA
Sbjct: 585 QQ--RQGPPQKPPGPAGP-----TRQASQAGPVPRTGPPTTQQP--------RPSGPGPA 629

Query: 357 LRRLP 361
            R  P
Sbjct: 630 GRPKP 634



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 49/202 (24%), Positives = 64/202 (31%), Gaps = 29/202 (14%)

Query: 101 EPDEGPEEPGEKFRR---------LAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPG 151
           +P  GP+  G   ++         L+G G     P P+  P+  + P       A P  G
Sbjct: 469 QPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQG 528

Query: 152 ----CDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHP--LFSPSHLTSKTPPPLYLPTE 205
                 P   G   P  +RP        +AGPP       +  P+   +   PP     +
Sbjct: 529 QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQ 588

Query: 206 GRRSDLPG--------GLAGP---RGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGG 254
           G     PG          AGP    G   T +   SG   P     P P L   P     
Sbjct: 589 GPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSG---PGPAGRPKPQLAQKPSQDVP 645

Query: 255 PPEYGLGDPPPPPGLLQPPTLA 276
           PP       PP P L   P  A
Sbjct: 646 PPATAAAGGPPHPQLKASPAQA 667



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 5/43 (11%)

Query: 263 PPPPPGLLQP-----PTLAPWQPSRGDGPPAVSSQPSGGRSLG 300
           PPPPPG   P     P  A  + S G  P A  + PS G S G
Sbjct: 31  PPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73


>gi|14249150 single stranded DNA binding protein 4 isoform a [Homo
           sapiens]
          Length = 385

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 77/248 (31%), Positives = 95/248 (38%), Gaps = 55/248 (22%)

Query: 133 AAPAMPSPDVVYGALPPPGCDPSGLGEAL----PAQSRPSPFRPAAPKAGPPGLVHPLFS 188
           +A A PSP  V G++ P     +G   A     P  S+PSP  P AP  GP G   P  S
Sbjct: 94  SAAAAPSP--VMGSMAPGDTMAAGSMAAGFFQGPPGSQPSPHNPNAPMMGPHG--QPFMS 149

Query: 189 PSH-------LTSKTPPPLYLPTEGRRSDLPGGLA-GPRGGLNTSRSLYSGLQNPCSTAT 240
           P         L   + PP  LP  G +  LPG +   PR   + S      +  P    T
Sbjct: 150 PRFPGGPRPTLRMPSQPPAGLP--GSQPLLPGAMEPSPRAQGHPS------MGGPMQRVT 201

Query: 241 PGPPLGSFPFLPGGPPEYGLGDPPPP-----PGL----LQPPTLAPWQPSRGDGPPAVSS 291
           P   + S      GP  YG G  PPP     PGL    + P    PW    G+  P  SS
Sbjct: 202 PPRGMASV-----GPQSYGGGMRPPPNSLAGPGLPAMNMGPGVRGPWASPSGNSIPYSSS 256

Query: 292 QPSGGRSLGEEGPPTRGASPPTPPVSIKSERLSPAPGGPGDFPK---TFPYPLLLARSLA 348
            P         GPP  G  P TP        + P+PG   +  +   T   P+      A
Sbjct: 257 SPG-----SYTGPPGGGGPPGTP--------IMPSPGDSTNSSENMYTIMNPIGQGAGRA 303

Query: 349 E-PLRPGP 355
             PL PGP
Sbjct: 304 NFPLGPGP 311


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 66/190 (34%), Positives = 74/190 (38%), Gaps = 38/190 (20%)

Query: 176 KAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNP 235
           KAGPPG       P     +   P  +P  G R   P G  GP                P
Sbjct: 185 KAGPPGGSSRAAFPQGGRGRGRFPGAVPG-GDRFPGPAGPGGPPPPF------------P 231

Query: 236 CSTATPGPPLGSFPFLPGGPPEYGLGDP-PPPPGLLQPPTLAPWQPSRGDGPPAVSSQPS 294
                P PPLG     P GPP    G P PPPPG + PP LA   P+RGD PP     P 
Sbjct: 232 AGQTPPRPPLG-----PPGPP----GPPGPPPPGQVLPPPLAG-PPNRGDRPPPPVLFP- 280

Query: 295 GGRSLGEEGPPTRGASPPTPPVSIKSERLSPA--------PGGPGDFPKTFPYPLLLARS 346
            G+  G+   P  G  PP PP  +      P         P  PG FP   P PL    +
Sbjct: 281 -GQPFGQ---PPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT 336

Query: 347 LAEPLR-PGP 355
           LA P   PGP
Sbjct: 337 LAPPPHLPGP 346



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 77/252 (30%), Positives = 90/252 (35%), Gaps = 58/252 (23%)

Query: 101 EPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEA 160
           E   GP  PG   R    +GG      P   P     P P    G  PPP   P+G    
Sbjct: 183 EGKAGP--PGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGP-AGPGGPPPPF--PAGQTPP 237

Query: 161 LPAQSRPSPFRPAAPKAGPPGLV--HPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGP 218
            P    P P  P  P   PPG V   PL  P +   + PPP+  P +            P
Sbjct: 238 RPPLGPPGP--PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ------------P 283

Query: 219 RGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPG-----GPPEYGLGDPPPP------- 266
            G            Q P     PGPP    P +PG     GPP    G PPPP       
Sbjct: 284 FG------------QPPLGPLPPGPP----PPVPGYGPPPGPPPPQQGPPPPPGPFPPRP 327

Query: 267 PGLL-QPPTLAPWQPSRGDGPPAVSSQPSGGRSLGEEGPPTRGASPPT----PPVSIKSE 321
           PG L  P TLAP  P    GPP  +  P+   +     PPT    P +    PP +    
Sbjct: 328 PGPLGPPLTLAP--PPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYG 385

Query: 322 RLSPAPGGPGDF 333
           R  P P   GD+
Sbjct: 386 R--PPPYDRGDY 395



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 63/194 (32%), Positives = 71/194 (36%), Gaps = 42/194 (21%)

Query: 86  ETLKRRGIGLDGPELEPDEGPEEPGEKFRR-LAG---EGGDPALP---------RPRLYP 132
           +T  R  +G  GP   P  GP  PG+     LAG    G  P  P         +P L P
Sbjct: 234 QTPPRPPLGPPGPPGPP--GPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291

Query: 133 AAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHL 192
             P  P P   YG  PPPG  P   G   P    P PF P  P  GP G    L  P HL
Sbjct: 292 LPPGPPPPVPGYG--PPPGPPPPQQGPPPP----PGPFPPRPP--GPLGPPLTLAPPPHL 343

Query: 193 TSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLP 252
               PPP   P     +  P     P           SG+  P S +   PP   +    
Sbjct: 344 PG--PPPGAPPPAPHVN--PAFFPPPTN---------SGM--PTSDSRGPPPTDPY---- 384

Query: 253 GGPPEYGLGDPPPP 266
           G PP Y  GD  PP
Sbjct: 385 GRPPPYDRGDYGPP 398


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.140    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,336,058
Number of Sequences: 37866
Number of extensions: 1958176
Number of successful extensions: 18513
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 310
Number of HSP's successfully gapped in prelim test: 1624
Number of HSP's that attempted gapping in prelim test: 8344
Number of HSP's gapped (non-prelim): 6759
length of query: 368
length of database: 18,247,518
effective HSP length: 104
effective length of query: 264
effective length of database: 14,309,454
effective search space: 3777695856
effective search space used: 3777695856
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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