BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|115527120 nebulin [Homo sapiens] (6669 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|115527120 nebulin [Homo sapiens] 1.354e+04 0.0 gi|46049105 nebulin-related anchoring protein isoform S [Homo sa... 1189 0.0 gi|46049092 nebulin-related anchoring protein isoform C [Homo sa... 1176 0.0 gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 631 e-180 gi|169217576 PREDICTED: similar to nebulin [Homo sapiens] 503 e-141 gi|239752495 PREDICTED: similar to nebulin [Homo sapiens] 253 3e-66 gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 123 5e-27 gi|47087157 nebulette non-muscle isoform [Homo sapiens] 102 1e-20 gi|20357552 cortactin isoform a [Homo sapiens] 64 7e-09 gi|20357556 cortactin isoform b [Homo sapiens] 64 7e-09 gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ... 60 7e-08 gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ... 60 7e-08 gi|19224660 protein kinase C and casein kinase substrate in neur... 59 2e-07 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 58 4e-07 gi|171906575 drebrin-like isoform c [Homo sapiens] 56 1e-06 gi|62198235 drebrin-like isoform b [Homo sapiens] 56 1e-06 gi|21361670 drebrin-like isoform a [Homo sapiens] 56 1e-06 gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo ... 55 2e-06 gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo s... 55 2e-06 gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo s... 55 3e-06 gi|24308229 protein kinase C and casein kinase substrate in neur... 54 4e-06 gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo s... 54 5e-06 gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo s... 54 5e-06 gi|7661700 sorbin and SH3 domain containing 1 isoform 2 [Homo sa... 54 5e-06 gi|78000160 sorbin and SH3 domain containing 1 isoform 1 [Homo s... 54 5e-06 gi|148747351 protein kinase C and casein kinase substrate in neu... 54 5e-06 gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ... 54 7e-06 gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo s... 53 9e-06 gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo s... 53 9e-06 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 53 9e-06 >gi|115527120 nebulin [Homo sapiens] Length = 6669 Score = 1.354e+04 bits (35143), Expect = 0.0 Identities = 6669/6669 (100%), Positives = 6669/6669 (100%) Query: 1 MADDEDYEEVVEYYTEEVVYEEVPGETITKIYETTTTRTSDYEQSETSKPALAQPALAQP 60 MADDEDYEEVVEYYTEEVVYEEVPGETITKIYETTTTRTSDYEQSETSKPALAQPALAQP Sbjct: 1 MADDEDYEEVVEYYTEEVVYEEVPGETITKIYETTTTRTSDYEQSETSKPALAQPALAQP 60 Query: 61 ASAKPVERRKVIRKKVDPSKFMTPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTP 120 ASAKPVERRKVIRKKVDPSKFMTPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTP Sbjct: 61 ASAKPVERRKVIRKKVDPSKFMTPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTP 120 Query: 121 ELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTK 180 ELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTK Sbjct: 121 ELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTK 180 Query: 181 DKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDV 240 DKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDV Sbjct: 181 DKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDV 240 Query: 241 AYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANA 300 AYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANA Sbjct: 241 AYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANA 300 Query: 301 RMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKAD 360 RMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKAD Sbjct: 301 RMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKAD 360 Query: 361 YNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDK 420 YNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDK Sbjct: 361 YNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDK 420 Query: 421 KYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYE 480 KYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYE Sbjct: 421 KYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYE 480 Query: 481 AIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIP 540 AIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIP Sbjct: 481 AIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIP 540 Query: 541 PDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKD 600 PDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKD Sbjct: 541 PDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKD 600 Query: 601 YEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQ 660 YEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQ Sbjct: 601 YEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQ 660 Query: 661 LKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQ 720 LKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQ Sbjct: 661 LKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQ 720 Query: 721 TITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGE 780 TITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGE Sbjct: 721 TITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGE 780 Query: 781 KFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS 840 KFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS Sbjct: 781 KFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS 840 Query: 841 DVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDML 900 DVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDML Sbjct: 841 DVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDML 900 Query: 901 QVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCG 960 QVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCG Sbjct: 901 QVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCG 960 Query: 961 WVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAK 1020 WVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAK Sbjct: 961 WVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAK 1020 Query: 1021 GEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAAR 1080 GEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAAR Sbjct: 1021 GEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAAR 1080 Query: 1081 QAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTP 1140 QAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTP Sbjct: 1081 QAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTP 1140 Query: 1141 HDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWM 1200 HDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWM Sbjct: 1141 HDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWM 1200 Query: 1201 KGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL 1260 KGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL Sbjct: 1201 KGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL 1260 Query: 1261 YKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAA 1320 YKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAA Sbjct: 1261 YKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAA 1320 Query: 1321 KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTS 1380 KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTS Sbjct: 1321 KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTS 1380 Query: 1381 YHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEY 1440 YHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEY Sbjct: 1381 YHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEY 1440 Query: 1441 NSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQL 1500 NSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQL Sbjct: 1441 NSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQL 1500 Query: 1501 SDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIP 1560 SDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIP Sbjct: 1501 SDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIP 1560 Query: 1561 IVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEA 1620 IVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEA Sbjct: 1561 IVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEA 1620 Query: 1621 SKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLY 1680 SKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLY Sbjct: 1621 SKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLY 1680 Query: 1681 KSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSN 1740 KSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSN Sbjct: 1681 KSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSN 1740 Query: 1741 KLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRP 1800 KLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRP Sbjct: 1741 KLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRP 1800 Query: 1801 DAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKK 1860 DAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKK Sbjct: 1801 DAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKK 1860 Query: 1861 GYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQS 1920 GYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQS Sbjct: 1861 GYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQS 1920 Query: 1921 DNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVL 1980 DNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVL Sbjct: 1921 DNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVL 1980 Query: 1981 AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGY 2040 AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGY Sbjct: 1981 AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGY 2040 Query: 2041 DLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDR 2100 DLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDR Sbjct: 2041 DLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDR 2100 Query: 2101 EYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMN 2160 EYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMN Sbjct: 2101 EYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMN 2160 Query: 2161 RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM 2220 RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM Sbjct: 2161 RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM 2220 Query: 2221 DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL 2280 DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL Sbjct: 2221 DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL 2280 Query: 2281 KKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKM 2340 KKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKM Sbjct: 2281 KKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKM 2340 Query: 2341 QSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQA 2400 QSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQA Sbjct: 2341 QSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQA 2400 Query: 2401 KKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIP 2460 KKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIP Sbjct: 2401 KKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIP 2460 Query: 2461 DAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYE 2520 DAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYE Sbjct: 2461 DAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYE 2520 Query: 2521 ELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHV 2580 ELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHV Sbjct: 2521 ELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHV 2580 Query: 2581 AKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDV 2640 AKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDV Sbjct: 2581 AKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDV 2640 Query: 2641 IHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFS 2700 IHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFS Sbjct: 2641 IHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFS 2700 Query: 2701 SLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKL 2760 SLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKL Sbjct: 2701 SLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKL 2760 Query: 2761 GLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWS 2820 GLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWS Sbjct: 2761 GLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWS 2820 Query: 2821 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ 2880 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ Sbjct: 2821 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ 2880 Query: 2881 SDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRF 2940 SDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRF Sbjct: 2881 SDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRF 2940 Query: 2941 KFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETL 3000 KFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETL Sbjct: 2941 KFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETL 3000 Query: 3001 YKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKM 3060 YKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKM Sbjct: 3001 YKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKM 3060 Query: 3061 MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCL 3120 MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCL Sbjct: 3061 MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCL 3120 Query: 3121 PDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPP 3180 PDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPP Sbjct: 3121 PDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPP 3180 Query: 3181 DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYS 3240 DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYS Sbjct: 3181 DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYS 3240 Query: 3241 ESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDD 3300 ESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDD Sbjct: 3241 ESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDD 3300 Query: 3301 PKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEW 3360 PKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEW Sbjct: 3301 PKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEW 3360 Query: 3361 ICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYR 3420 ICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYR Sbjct: 3361 ICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYR 3420 Query: 3421 QRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRI 3480 QRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRI Sbjct: 3421 QRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRI 3480 Query: 3481 NYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNI 3540 NYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNI Sbjct: 3481 NYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNI 3540 Query: 3541 KDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPL 3600 KDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPL Sbjct: 3541 KDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPL 3600 Query: 3601 HEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDR 3660 HEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDR Sbjct: 3601 HEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDR 3660 Query: 3661 KYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKS 3720 KYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKS Sbjct: 3661 KYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKS 3720 Query: 3721 NSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGA 3780 NSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGA Sbjct: 3721 NSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGA 3780 Query: 3781 QSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYR 3840 QSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYR Sbjct: 3781 QSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYR 3840 Query: 3841 NYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIF 3900 NYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIF Sbjct: 3841 NYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIF 3900 Query: 3901 CDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINL 3960 CDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINL Sbjct: 3901 CDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINL 3960 Query: 3961 ARANALNVSNKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYV 4020 ARANALNVSNKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYV Sbjct: 3961 ARANALNVSNKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYV 4020 Query: 4021 GTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMD 4080 GTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMD Sbjct: 4021 GTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMD 4080 Query: 4081 YRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAAD 4140 YRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAAD Sbjct: 4081 YRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAAD 4140 Query: 4141 IFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLH 4200 IFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLH Sbjct: 4141 IFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLH 4200 Query: 4201 TAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGH 4260 TAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGH Sbjct: 4201 TAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGH 4260 Query: 4261 YVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSD 4320 YVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSD Sbjct: 4261 YVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSD 4320 Query: 4321 IDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKN 4380 IDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKN Sbjct: 4321 IDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKN 4380 Query: 4381 QEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPD 4440 QEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPD Sbjct: 4381 QEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPD 4440 Query: 4441 TPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYE 4500 TPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYE Sbjct: 4441 TPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYE 4500 Query: 4501 KQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQ 4560 KQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQ Sbjct: 4501 KQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQ 4560 Query: 4561 YILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQIL 4620 YILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQIL Sbjct: 4561 YILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQIL 4620 Query: 4621 HAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKY 4680 HAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKY Sbjct: 4621 HAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKY 4680 Query: 4681 TTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKY 4740 TTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKY Sbjct: 4681 TTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKY 4740 Query: 4741 REEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVT 4800 REEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVT Sbjct: 4741 REEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVT 4800 Query: 4801 AKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWD 4860 AKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWD Sbjct: 4801 AKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWD 4860 Query: 4861 TPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVH 4920 TPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVH Sbjct: 4861 TPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVH 4920 Query: 4921 SVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMS 4980 SVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMS Sbjct: 4921 SVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMS 4980 Query: 4981 SYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPE 5040 SYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPE Sbjct: 4981 SYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPE 5040 Query: 5041 IRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKG 5100 IRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKG Sbjct: 5041 IRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKG 5100 Query: 5101 FGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELV 5160 FGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELV Sbjct: 5101 FGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELV 5160 Query: 5161 YRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAK 5220 YRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAK Sbjct: 5161 YRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAK 5220 Query: 5221 DVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTV 5280 DVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTV Sbjct: 5221 DVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTV 5280 Query: 5281 KDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDL 5340 KDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDL Sbjct: 5281 KDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDL 5340 Query: 5341 TWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQL 5400 TWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQL Sbjct: 5341 TWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQL 5400 Query: 5401 MNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPE 5460 MNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPE Sbjct: 5401 MNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPE 5460 Query: 5461 HLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNK 5520 HLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNK Sbjct: 5461 HLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNK 5520 Query: 5521 SNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDF 5580 SNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDF Sbjct: 5521 SNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDF 5580 Query: 5581 EYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLA 5640 EYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLA Sbjct: 5581 EYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLA 5640 Query: 5641 KTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKS 5700 KTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKS Sbjct: 5641 KTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKS 5700 Query: 5701 NYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEY 5760 NYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEY Sbjct: 5701 NYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEY 5760 Query: 5761 RAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVM 5820 RAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVM Sbjct: 5761 RAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVM 5820 Query: 5821 KDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHT 5880 KDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHT Sbjct: 5821 KDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHT 5880 Query: 5881 IPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKD 5940 IPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKD Sbjct: 5881 IPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKD 5940 Query: 5941 YEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAK 6000 YEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAK Sbjct: 5941 YEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAK 6000 Query: 6001 NATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANF 6060 NATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANF Sbjct: 6001 NATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANF 6060 Query: 6061 TSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQ 6120 TSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQ Sbjct: 6061 TSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQ 6120 Query: 6121 CDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMMRVKQTQDHI 6180 CDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMMRVKQTQDHI Sbjct: 6121 CDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMMRVKQTQDHI 6180 Query: 6181 SSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTPEIERVKRNQE 6240 SSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTPEIERVKRNQE Sbjct: 6181 SSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTPEIERVKRNQE 6240 Query: 6241 NFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENMGKGTPLAVTPEMERVKHN 6300 NFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENMGKGTPLAVTPEMERVKHN Sbjct: 6241 NFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENMGKGTPLAVTPEMERVKHN 6300 Query: 6301 QENISSVLYKENVGKATATPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVK 6360 QENISSVLYKENVGKATATPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVK Sbjct: 6301 QENISSVLYKENVGKATATPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVK 6360 Query: 6361 RNQENFSSVLYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDT 6420 RNQENFSSVLYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDT Sbjct: 6361 RNQENFSSVLYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDT 6420 Query: 6421 PEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYRGIQRKV 6480 PEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYRGIQRKV Sbjct: 6421 PEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYRGIQRKV 6480 Query: 6481 VEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSREQSRS 6540 VEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSREQSRS Sbjct: 6481 VEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSREQSRS 6540 Query: 6541 ASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTT 6600 ASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTT Sbjct: 6541 ASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTT 6600 Query: 6601 VSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGM 6660 VSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGM Sbjct: 6601 VSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGM 6660 Query: 6661 LPANYVEAI 6669 LPANYVEAI Sbjct: 6661 LPANYVEAI 6669 >gi|46049105 nebulin-related anchoring protein isoform S [Homo sapiens] Length = 1730 Score = 1189 bits (3075), Expect = 0.0 Identities = 619/1546 (40%), Positives = 974/1546 (63%), Gaps = 55/1546 (3%) Query: 456 KNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHT-YKVHPDK--TKFTQVTDSPVLL 512 + Y +YE+ RGKG FP IT Y+ KK +Q YK D+ ++F+ V D+P LL Sbjct: 155 EEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELL 214 Query: 513 QAQVNSKQLSDLNYKAKHESEKFKCHIPPD-TPAFIQHKVNAYNLSDNLYKQDWEKSKAK 571 +++ ++ SD+ Y +E ++ K P TPA+ K SD Y Q ++K Sbjct: 215 RSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRG 274 Query: 572 KFDIKVDAIPLLA----------------------------------AKANTKNTSDVMY 597 + A +L AK + SD+ Y Sbjct: 275 MAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKY 334 Query: 598 KKDYEKNKGKM-IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQ 656 ++D+ K KG L D+ + + V K S+ YK++ E ++ S+NYCETP+++ Sbjct: 335 RQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFR 394 Query: 657 LDTQLKNF-SEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGK 715 +++ F S+ +YK+ Y + G Y G D H MKV + S+ +YKA+Y+ D Sbjct: 395 NVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVD 454 Query: 716 CYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKA 775 +P T+T Y+ KL KD Y+ DK K+++VTD+P ++QA++N +QLS +NY+A Sbjct: 455 YNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRA 514 Query: 776 KHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKAN 835 +E K +P D PQ ++ + NA S+ YK+ WEK+K K F++K+DA+ LLAAKA+ Sbjct: 515 DYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKAS 574 Query: 836 TKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTA 895 + S++ YK++YEK+KGK +G D ++LHSL+ AK S+ EY+K +E+SKT + Sbjct: 575 GELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHL 630 Query: 896 PLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSW 955 P+DM+ + AKK+Q +ASD+DY+ LH Y+ P+ + AKKAY LQS+++YKAD +W Sbjct: 631 PMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL-AW 689 Query: 956 MKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDI 1015 MKG GW+ GSL +E+AK+A +++EK YRQ D LKFTS+ D+ +K +Q +S + Sbjct: 690 MKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGV 749 Query: 1016 AYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRA 1075 AYKA E+ +H+Y + D P F+QA+ NA N+SE +YK+ ++ KG++LR D++ A Sbjct: 750 AYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLA 809 Query: 1076 AKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKS 1135 AKA R AS+V+YK+DYE+++GK++G + +Q D ++ H + ++K+QS+ EYKK +E TKS Sbjct: 810 AKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKS 869 Query: 1136 KYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKED 1195 + + DM ++V A+KAQ + ++V YK + HH+T LP M +E +K +QSDN Y+ D Sbjct: 870 QCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRAD 929 Query: 1196 YNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQ 1255 WMKG+GW+ GSL+VE+ KKAG+ ++EKKYRQHPD LKFTSI D+P MVQA+ + Q Sbjct: 930 VK-WMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQ 988 Query: 1256 VSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAI 1315 D LY+ +GE++KH YT + DLP+ L AK NA NIS+ YK W L G + DA+ Sbjct: 989 AVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDAL 1048 Query: 1316 PITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYE 1375 P AAKAS I SDYKYKEA+EK KG+ +G RSL+DD L H + LQSD YKK +E Sbjct: 1049 PFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFE 1108 Query: 1376 NTKTSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNV 1435 ++K +H P DM ++ AK AQ +A+N +YK PL YT L + + L + +++QS+N+ Sbjct: 1109 HSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENL 1168 Query: 1436 YKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQH 1495 Y+ + N F++G+ + G+LE+E KKA + ++E KYRQHP + K+T+V D+ ++ A+ Sbjct: 1169 YRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKF 1227 Query: 1496 NTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLR 1555 + + ++ YK GE +H+YT+ LP+FI+AK NA N+SDA YK W+ A+GY L Sbjct: 1228 SNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLT 1287 Query: 1556 PDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYK 1615 +A+P AA++S +IASD Y+ + K +GK +G S++DDP++ H + ++QS+ +Y+ Sbjct: 1288 IEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1347 Query: 1616 KGYEASKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQ 1675 +G +S+ ++H P+DMV + AK +Q +A++ +YR YH +T LP+ L + ++ A +Q Sbjct: 1348 RGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQ 1407 Query: 1676 SDNLYKSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQA 1735 S+ YKSD MKGIGW+ + S ++E AKKAGE++SE KYR+ P+ +KFT +D+ + Sbjct: 1408 SELRYKSDLIG-MKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLV 1466 Query: 1736 LNKSNKLNMDKRLYTEKWNKDKTTIH---VMPDTPDILLSRVNQITMSDKLYKAGWEEEK 1792 K++ ++ ++R+Y + D ++H ++PD PD +R+N + +SDK+Y+ WE+ + Sbjct: 1467 HAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTR 1523 Query: 1793 KKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKM 1852 YD R DAI + ARASR+IASD++YK+A+ + +G IG+RS++DDP++ HF+ V ++ Sbjct: 1524 AGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRL 1583 Query: 1853 QSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELA 1912 QSD EYKK + KS++ FH+ D ++ AK+SQ++A++ +YR + P+ + A Sbjct: 1584 QSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHA 1643 Query: 1913 KNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEK 1958 + Q+QSD +YK+D + +G+GW P GS + E ++A E+ + + Sbjct: 1644 QKAHQLQSDVKYKSD-LNLTRGVGWTPPGSYKVEMARRAAELANAR 1688 Score = 1135 bits (2936), Expect = 0.0 Identities = 619/1646 (37%), Positives = 983/1646 (59%), Gaps = 57/1646 (3%) Query: 109 KGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVS 168 K + S TP ++ + +S + + DG+ K++ H D K+KD E A + Sbjct: 60 KNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLAN 119 Query: 169 KVLYKQNWEDTKDKYLLPPDA---PELVQAVKNTAMFSKKLYTEDWEADKSL-FYPYNDS 224 + Y W + P A PE+V+ V+ ++ YTED+E + +P + Sbjct: 120 ERAY---WTGYGEGNAWCPGALPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMIT 175 Query: 225 PELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENK 284 P +R +A + S V YK+G E+ ++F+ + D P++ +K S +Y EDYE + Sbjct: 176 PAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQ 235 Query: 285 IKGKWSE----TPCFEVANAR------------------------MNADNISTRK----- 311 +GK S TP +++A + A+ I TR+ Sbjct: 236 -RGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294 Query: 312 ---YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASE 368 Y E++E + + F TP Y+ KKA AS +KY++D+ K KG A Y+ LPA + Sbjct: 295 GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQD 354 Query: 369 NPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLK 428 N L+Q ++ +S+ YK++ E ++ SINYCETP+F+ + + F+SD KYK++Y Sbjct: 355 NLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQN 414 Query: 429 DILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQC 488 + G Y G D H MKV + S+ YKA+Y+ D +P T+T Y+ KL Sbjct: 415 HMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPL 474 Query: 489 KDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQ 548 KD Y+ DK K++ VTD+P ++QA++N++QLS +NY+A +E K +P D P ++ Sbjct: 475 KDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVK 534 Query: 549 HKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKM 608 K NA S+ YK+ WEK+K K F++K+DA+ LLAAKA+ + S++ YK++YEK KGK Sbjct: 535 AKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA 594 Query: 609 IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEAR 668 +G D ++LHSL++AK S+ YK+ +E++K + P ++ + ++ Sbjct: 595 MGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR----FHLPMDMVNIRHAKKAQTL 646 Query: 669 YKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEA 728 DL + L Y ED K S+ YKA+ KG + + +A Sbjct: 647 ASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQA 706 Query: 729 IKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPA 788 K + Y+ D+ KFT+VTDS + A+ + + S + YKA +E + I Sbjct: 707 KKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISK 766 Query: 789 DAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDY 848 D P F+Q R NA NLS+ +YK WE KAK F++++D++ LAAKA S+V YK+DY Sbjct: 767 DEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDY 826 Query: 849 EKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKS 908 E+S+GK+IGA + D +M HSL+ +K QS+ EY+K +E +K+ LDM+ + A+K+ Sbjct: 827 ERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKA 886 Query: 909 QAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLE 968 Q +A+DV YK H ++ P + V+ AKKAY LQSD +Y+AD WMKG GWV GSL Sbjct: 887 QHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLN 945 Query: 969 MEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKY 1028 +E+AK+A ++++EKKYRQHPD LKFTSI+D P VQ++I+ Q D Y+ +GE I H Y Sbjct: 946 VEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHY 1005 Query: 1029 NLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQY 1088 DLP+ + AK+NA NISE YK L GY LR DA+P +AAKA+ + SD +Y Sbjct: 1006 TPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKY 1065 Query: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA 1148 K+ +EK KG+M+G +SL+DD L H + +QSD YKK +E +K++++ P DM +V Sbjct: 1066 KEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVH 1125 Query: 1149 AKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPI 1208 AKKAQ + SN +YKH L YT L + + L +K ++QS+N+Y+ D N+M+G+ + Sbjct: 1126 AKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL-NFMRGVACVIP 1184 Query: 1209 GSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDV 1268 G+L++E KKA + ++E KYRQHP + K+T++ D+P ++ AK + + ++ LYKA GED Sbjct: 1185 GTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDA 1244 Query: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328 +H+YTM+ LP+F++AK NA N+SD YK W +L A+G + +A+P AA+AS +IAS Sbjct: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304 Query: 1329 DYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV 1388 D+ Y+ + K +GK +G +S++DDP++ H + +LQS+ +Y++ +++ +H P DMV Sbjct: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMV 1364 Query: 1389 SITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIG 1448 + AK AQ +A++ +Y+ H +T LP+ + + + + +QS+ YK + +KGIG Sbjct: 1365 HLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIG 1423 Query: 1449 WIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVE 1508 W+ + S ++E KKAG+ ++E KYR+ PD++KFT+V DS +V A+++ ++ Y+ Sbjct: 1424 WLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSG 1483 Query: 1509 GEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSR 1568 + H+YT+ P+ P F +A++NAL++SD Y+ W++T A YD R DAIP A++SR Sbjct: 1484 DAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASR 1543 Query: 1569 NIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTP 1628 IASD +YKEA+ + +G Q+G+ S+ DDP++ H++NV ++QSD EYKK + S++++H+ Sbjct: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1603 Query: 1629 LDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWM 1688 D + AK+SQ++A++ +YRQ T P+ L + H++ A Q+QSD YKSD N Sbjct: 1604 TDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDL-NLT 1662 Query: 1689 KGIGWVPIESLEVEKAKKAGEILSEK 1714 +G+GW P S +VE A++A E+ + + Sbjct: 1663 RGVGWTPPGSYKVEMARRAAELANAR 1688 Score = 1038 bits (2683), Expect = 0.0 Identities = 592/1602 (36%), Positives = 935/1602 (58%), Gaps = 82/1602 (5%) Query: 1108 DPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA-AKKAQDVVSNVNYKHS-- 1164 DP++V + K + EY +DYE+ + K + P + AKKA + S V YK Sbjct: 140 DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198 Query: 1165 --LHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDA 1222 + ++ + D +L SK Q+QSD Y EDY +G G P ++ K + Sbjct: 199 ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ-QRGKGSFPAMITPAYQIAKRANE 257 Query: 1223 LNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL---YKAKGEDVKHKYTMSPDL- 1278 L R H K + P + T++ +D Y + E+ + K + + Sbjct: 258 L-ASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMIT 316 Query: 1279 PQFLQAKCNAYNISDVCYKRD---------WHDLIAKGNNVLGDAIPITAAKASRNIASD 1329 P + AK SD+ Y++D +H L A+ N VL A ++ + S+ Sbjct: 317 PAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQA------QSVNKLVSE 370 Query: 1330 YKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYEN-TKTSYHTPG-DM 1387 +YK+ E S+G + + + P+ + ++K SD +YK+NY+N + Y G D Sbjct: 371 VEYKKDLESSRGHSINYC---ETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDR 427 Query: 1388 VSITAAK---MAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFL 1444 ++ A K +A +VA +YK + Y Y P ++ Y + + Sbjct: 428 RTLHAMKVGSLASNVAYKADYKHDIVDYNY-PATLT-----------------PSYQTAM 469 Query: 1445 KGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLN 1504 K + L + YRQ D +K++SV D+ +V A+ N +QLS +N Sbjct: 470 KLV------------------PLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVN 511 Query: 1505 YKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAA 1564 Y+ + EK K YT+ ++PQ ++AK NA S+ YK W+KT KG++++ DA+ ++AA Sbjct: 512 YRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 571 Query: 1565 KSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK 1624 K+S +AS+ KYKE YEK KGK +G D +L+H + +AK+ S+ EYKKG+E SKT+ Sbjct: 572 KASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR 627 Query: 1625 YHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDF 1684 +H P+DMV++ AKK+Q +A++ +YR+ H YT+LP+ + + ++ A +QS+ YK+D Sbjct: 628 FHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL 687 Query: 1685 TNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNM 1744 WMKG+GW+ SL +E+AKKAG+++SEK YRQ ++LKFT D+ + K ++ Sbjct: 688 A-WMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQ 746 Query: 1745 DKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIA 1804 Y + + D P L +R N +S+KLYK+ WE +K KG++LR D++ Sbjct: 747 SGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLT 806 Query: 1805 IKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEK 1864 AA+A RD+AS+ KYK+ YE+++GK IG + ++ D ++ H +Q++K+QS+ EYKKG+E Sbjct: 807 FLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFED 866 Query: 1865 SKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQY 1924 +K+ H +DM+ +V A+K+Q +AT+ Y+ H + LP M E AK +QSDNQY Sbjct: 867 TKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQY 926 Query: 1925 KADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNN 1984 +AD +MKG+GW+ GSL E+ KKA E+ISEKKYRQHPD LK++++ D+ MV A+ + Sbjct: 927 RAD-VKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARIS 985 Query: 1985 AKIMNEHLYKQAWEADKTKVHIMP--DIPQIILAKANAINMSDKLYKLSLEESKKKGYDL 2042 + LY++ + + K H P D+P+++LAK NA+N+S+ YK S + + GY L Sbjct: 986 YTQAVDRLYRE--QGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKL 1043 Query: 2043 RPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREY 2102 R DA+P +AAKAS +I SDYKYK +EK KG+M+G RSLEDD L HS+ +QSD Y Sbjct: 1044 RLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNY 1103 Query: 2103 KKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRI 2162 KK +E++K +H P DM ++ AK AQ +N +YKH + +Y L + + + + +++ Sbjct: 1104 KKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKL 1163 Query: 2163 QSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDM 2222 QS+N Y+ D N + +G+ G+LE+E KKA+E S+ KYRQHP +F++ +TD+ ++ Sbjct: 1164 QSENLYRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNL 1222 Query: 2223 VLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKK 2282 + AK + N+ LY + + + P+ ++AK N S YK W + Sbjct: 1223 LHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQ 1282 Query: 2283 GYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQS 2342 GY L ++A+ Q A+AS DIASD+ Y+ + K+ G +G +S++DDP++ + ++QS Sbjct: 1283 GYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQS 1342 Query: 2343 EREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKK 2402 E +Y++ + +F P+DM+ +V AK Q L SD DY+ H++T LP+ + AKK Sbjct: 1343 ELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKK 1402 Query: 2403 VYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDA 2462 + LQSE YKSDL ++GIGW L S + E K+A E+ISE KYR+ PD KFT++ D+ Sbjct: 1403 AHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDS 1462 Query: 2463 MDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEEL 2522 D+V AK + + ++R+YR + + ++PD PD A+ N ++ SDK+YR +E+ Sbjct: 1463 PDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQT 1522 Query: 2523 KRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAK 2582 + YD +DAIP + A+ASREIAS+++YKE F + G IG R+++DDP+M ++V + Sbjct: 1523 RAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGR 1582 Query: 2583 IQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIH 2642 +QSD EYKKDF K +++F S D G++ AK+ Q L SDV Y+ L Q TC P+Q + H Sbjct: 1583 LQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRH 1642 Query: 2643 ARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQI 2684 A++A+ LQSD YKSDL +G+GW GS + E +RA ++ Sbjct: 1643 AQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1684 Score = 1022 bits (2642), Expect = 0.0 Identities = 603/1626 (37%), Positives = 937/1626 (57%), Gaps = 61/1626 (3%) Query: 2050 KAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENT 2109 + A + +A++ Y Y +G G DP++V ++ K + EY ++YE Sbjct: 109 EGAPNRQPLANERAYWTGYGEGNAWCPGALP---DPEIVRMVEARKSLGE-EYTEDYEQP 164 Query: 2110 KTSYHTPADML-SVTAAKDAQANITNTNYKH----LIHKYILLPDAMNIELTRNMNRIQS 2164 + PA + + AK A + YK I ++ + D + ++ ++QS Sbjct: 165 RGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQS 224 Query: 2165 DNEYKQDYNEWYKGLGWSPAGSLEVEK-AKKATEYASDQKYRQHPSNFQFKKLTDSMDMV 2223 D Y +DY E +G G PA + AK+A E ASD +Y Q K++ Sbjct: 225 DVRYTEDY-EQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQ----KEMRGMAGPA 279 Query: 2224 LAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKG 2283 + + T ++ Y Q Y +EE KG Sbjct: 280 IGAEGILT-----------------------------RECADQYGQG-YPEEYEEHRGKG 309 Query: 2284 YDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGH-HVGFRSLQDDPKLVLSMNVAKMQS 2342 + + Q AK + ++ASD KY+Q + K G H QD+ L + +V K+ S Sbjct: 310 SFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369 Query: 2343 EREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYK-NYLH----QWTCLPDQNDV 2397 E EYKKD E + + + K + SD YK NY + ++ + Sbjct: 370 EVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRT 429 Query: 2398 VQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFT 2457 + A KV L S YK+D + P + + + + YRQ D+ K++ Sbjct: 430 LHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 489 Query: 2458 SIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRM 2517 S+ D IV AK NA+ S YR ++K+K + D P +V AK N S+ Y+ Sbjct: 490 SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 549 Query: 2518 GYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWS 2577 G+E+ K KG+++ +DA+ + AAKAS E+AS KYKE + K G +G D +++ S Sbjct: 550 GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 605 Query: 2578 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ 2637 + +AK+ S+ EYKK FE+ KT+F P+DM+ + AKK QTL SD+DY+ LH++T LP+ Sbjct: 606 LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 665 Query: 2638 SDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQF 2697 A++AY LQS+ YK+DL W+KG+GW+T GSL E+ K+A Q++S+ YRQ D+ Sbjct: 666 MKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725 Query: 2698 KFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKL 2757 KF+S+ DS M AK + + Y ++ I D P L A+ N N SEKL Sbjct: 726 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785 Query: 2758 YKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKM 2817 YK E K KG+++R+D++ AAKA RD+ASE KYKE Y + G IGA+ ++ D +M Sbjct: 786 YKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQM 845 Query: 2818 MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCL 2877 S+ ++K+QS+ EYKK FE K++ +DM+ +V A+K Q L +DV YK H +T L Sbjct: 846 SHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905 Query: 2878 PDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPP 2937 P V A++AY LQSDN Y++D++WM+G+GWV+ GSL+VE+ K+A E++S+K YRQ P Sbjct: 906 PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 965 Query: 2938 DRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYS 2997 D KFTS+ D+ E V A+ + RLY E + K D PE++LA+ N +N S Sbjct: 966 DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 1025 Query: 2998 ETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDD 3057 ET YK + + + GY LR DA+P AAKAS ++ISDYKYK+ + K G +G+R++EDD Sbjct: 1026 ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1085 Query: 3058 PKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEW 3117 + S++ +QSD YKK FE K +F P+DM +V AKK QTL S+ DYK+ L ++ Sbjct: 1086 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1145 Query: 3118 TCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYR 3177 T L + + A++A+ LQS+N+Y+SDL ++RG+ V G++++ K+A+E++S++ YR Sbjct: 1146 TSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYR 1205 Query: 3178 QPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKI 3237 Q P K+T+VTD+ + AK + N+RLY A + + + + PE + A+ N Sbjct: 1206 QHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAA 1265 Query: 3238 NYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAV 3297 N S++ Y+++ + +GY L +A+P AA+AS DIASD+ Y+ + K+ G IG ++V Sbjct: 1266 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSV 1325 Query: 3298 HDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPL 3357 DDP+I + ++QS+ +Y++ + ++ P+DM+ +V AK Q L SD DY+ Sbjct: 1326 RDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQY 1385 Query: 3358 HEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDT 3417 H++ LP+ + A+KA+ LQS+ YKSDL MKGIGW+ + S ++ AK+AGEL+S+T Sbjct: 1386 HKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISET 1445 Query: 3418 IYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIH---VMPDTPEIML 3474 YR++P+++KFT++ D+P+ V AKN+ ++ N+R+Y D +++H ++PD P+ Sbjct: 1446 KYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTR 1502 Query: 3475 AKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHH 3534 A+LN ++ SDK+Y+ + E+++ YD RLDAIP Q A+ASR+IASD++YKE + + G Sbjct: 1503 ARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQ 1562 Query: 3535 IGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDI 3594 IG R++ DDP+M ++V ++QSD EYKK+F K +++F S D G++ AK+ Q L SD+ Sbjct: 1563 IGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDV 1622 Query: 3595 DYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAG 3654 Y+ PL + TC P+Q + A+KA+ LQSD YKSDL RG+GW P GS +VE +RA Sbjct: 1623 HYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAA 1682 Query: 3655 EILSDR 3660 E+ + R Sbjct: 1683 ELANAR 1688 Score = 1021 bits (2639), Expect = 0.0 Identities = 589/1588 (37%), Positives = 926/1588 (58%), Gaps = 59/1588 (3%) Query: 2328 DPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQELVSDVDYKN--- 2383 DP++V + K E EY +D+E+ + K S P + AKK +L S V+YK Sbjct: 140 DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198 Query: 2384 -YLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEK-NKRASEI 2441 + +++ + D +++++K +LQS+ Y D E RG G P A + KRA+E+ Sbjct: 199 ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANEL 258 Query: 2442 ISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIV 2501 S+ +Y Q + A+ L RE D+ Sbjct: 259 ASDVRYHQQYQKEMRGMAGPAI----------GAEGILTRECADQ--------------- 293 Query: 2502 LAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGH 2561 + Y YEE + KG + + AK + E+AS+ KY++ F K G Sbjct: 294 ---------YGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGA 344 Query: 2562 -HIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVS 2620 H + +D+ + + V K+ S+ EYKKD E + + + K S Sbjct: 345 AHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTS 404 Query: 2621 DVDYK-NYLH----QWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLED 2675 D YK NY + ++ + +HA + L S+ YK+D + + + +L Sbjct: 405 DNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKH-DIVDYNYPATLTP 463 Query: 2676 EKNKRATQI-LSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTV 2734 + L D YRQ D+ K+SS+ D+ +V AK NA ++H Y ++K+K Sbjct: 464 SYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNY 523 Query: 2735 HIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKY 2794 + D P+++ AK N +SE YK G E+ K KG++M++DA+ + AAKAS ++AS KY Sbjct: 524 TLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKY 583 Query: 2795 KEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL 2854 KE Y K G +G D +++ S+ +AK+ S+ EYKK FE+ KT+F P+DM+ + Sbjct: 584 KEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRH 639 Query: 2855 AKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIG 2914 AKK QTL SD+DY+ LH++T LP+ A++AY LQS+ YK+DL WM+G+GW++ G Sbjct: 640 AKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEG 699 Query: 2915 SLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDK 2974 SL++E+ K+A +++S+K YRQ D KFTSVTDS + AK + + Y ++ Sbjct: 700 SLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV 759 Query: 2975 TQIHIMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISD 3034 Q I D P + AR N N SE LYK + E K KG++LR D++ +AAKA RD+ S+ Sbjct: 760 HQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASE 819 Query: 3035 YKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLG 3094 KYK+ Y + G IGA++++ D +M S+ ++K+QS+ EYKK FE K++ +DM+ Sbjct: 820 VKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVH 879 Query: 3095 VVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWV 3154 +V A+K Q L +DV YK H +T LP V A++AY LQSDN Y++D++W++G+GWV Sbjct: 880 LVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWV 939 Query: 3155 PIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWD 3214 GS++V + K+A E++S+ YRQ PD LKFTS+ D+ E V A+ + RLY E + Sbjct: 940 ATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGE 999 Query: 3215 KDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDI 3274 K D PE++LA+ N +N SE+ Y+++ + + GY LR DA+P AAKAS +I Sbjct: 1000 NIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEI 1059 Query: 3275 ASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVD 3334 SDYKYKEA+ K G +G+R++ DD + S++ +QSD YKK FE K ++ P+D Sbjct: 1060 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1119 Query: 3335 MLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGI 3394 M +V AKK QTL S+ DYKHPL ++ L + + A+KA+ LQS+NLY+SDL +M+G+ Sbjct: 1120 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1179 Query: 3395 GWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTE 3454 V +LE+ K+A EL+S++ YRQ P + K+T++TDTP + AK + N+RLY Sbjct: 1180 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKA 1239 Query: 3455 AWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKAS 3514 A ++ + + PE + AK N N SD YK + + +GY L ++A+P QAA+AS Sbjct: 1240 AGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARAS 1299 Query: 3515 RDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSS 3574 DIASD+ Y+ + K+ G IG ++++DDP++ + ++QS+ +Y++ + +F Sbjct: 1300 GDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHL 1359 Query: 3575 PVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWL 3634 P+DM+ +V AK Q L SD DY+ H++T LP+ + A+KA+ LQS+ YKSDL + Sbjct: 1360 PMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGM 1419 Query: 3635 RGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHL 3694 +GIGW+ + S ++E K+AGE++S+ KYR+ D +KFT + D+P++V AKN+ + ++ + Sbjct: 1420 KGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERM 1479 Query: 3695 YTEAWDADKTSIH---VMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISI 3751 Y D S+H ++PD PD A+ N+ ++S K+Y W++++ YD R DAI Sbjct: 1480 YR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPF 1536 Query: 3752 KSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKW 3811 ++A+ASR+IASD++YKEA+ + +G IG +S++DDP++ ++ G++QS+ EYKK+F K Sbjct: 1537 QTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKS 1596 Query: 3812 KTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYK 3871 +++F S D +L AK+ Q L +D+ YR L + TC P+Q + A+KA+ LQSD YK Sbjct: 1597 RSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYK 1656 Query: 3872 ADLEWLRGIGWMPQGSPEVLRVKNAQNI 3899 +DL RG+GW P GS +V + A + Sbjct: 1657 SDLNLTRGVGWTPPGSYKVEMARRAAEL 1684 Score = 979 bits (2531), Expect = 0.0 Identities = 582/1622 (35%), Positives = 924/1622 (56%), Gaps = 63/1622 (3%) Query: 2537 KAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKW 2596 + A + +A+E Y G+ + GA DP+++ + K + EY +D+E+ Sbjct: 109 EGAPNRQPLANERAYWTGYGEGNAWCPGAL---PDPEIVRMVEARKSLGE-EYTEDYEQP 164 Query: 2597 KTKFSSPVDMLGVVL-AKKCQTLVSDVDYKN----YLHQWTCLPDQSDVIHARQAYDLQS 2651 + K S P + AKK L S V+YK + +++ + D +++ ++ LQS Sbjct: 165 RGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQS 224 Query: 2652 DNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLA 2711 D Y D + +G G F +++ + Sbjct: 225 DVRYTEDYEQQRGKG-------------------------------SFPAMITPAYQIAK 253 Query: 2712 KNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYD 2771 + N + + R Y + + K+ + E +L ++ Y + Y EE + KG Sbjct: 254 RANELASDVR-YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQG-YPEEYEEHRGKGSF 311 Query: 2772 MRVDAIPIKAAKASRDIASEFKYKEGYRKQLGH-HIGARAIRDDPKMMWSMHVAKIQSDR 2830 + + AK + ++AS+ KY++ + K G H + +D+ + + V K+ S+ Sbjct: 312 PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371 Query: 2831 EYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYK-NYLH----QWTCLPDQSDVIH 2885 EYKKD E + + + K SD YK NY + ++ + +H Sbjct: 372 EYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLH 431 Query: 2886 ARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEI--LSDKIYRQPPDRFKFT 2943 A + L S+ YK+D + I + + + A ++ L D YRQ D+ K++ Sbjct: 432 AMKVGSLASNVAYKAD--YKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 489 Query: 2944 SVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKL 3003 SVTD+ + V AK NA ++ Y ++K+K + D P+++ A+ N +SE YK Sbjct: 490 SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 549 Query: 3004 ANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWS 3063 E+ K KG++++ DA+ ++AAKAS ++ S+ KYK+ Y K G +G D +++ S Sbjct: 550 GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 605 Query: 3064 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQ 3123 + +AK+ S+ EYKK FE+ KT+F P+DM+ + AKK QTL SD+DY+ LHE+T LP+ Sbjct: 606 LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 665 Query: 3124 NDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPPDKL 3183 A++AY LQS+ YK+DL W++G+GW+ GS+++ + K+A +++S+ YRQ D+L Sbjct: 666 MKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725 Query: 3184 KFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESL 3243 KFTSVTDS + AK + + Y ++ Q I D P + AR N N SE L Sbjct: 726 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785 Query: 3244 YRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKI 3303 Y+ + E K +G++LR D++ +AAKA RD+AS+ KYKE Y + G IGA+ V D ++ Sbjct: 786 YKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQM 845 Query: 3304 MWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICL 3363 SL ++K+QS+ EYKK FE K++ +DM+ +V A+K Q L +DV YK H + L Sbjct: 846 SHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905 Query: 3364 PDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRP 3423 P + A+KAY LQSDN Y++D++WMKG+GWV SL V +AK+AGEL+S+ YRQ P Sbjct: 906 PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 965 Query: 3424 ETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYS 3483 + LKFTSI DTPE V A+ + RLY E +N K D PE++LAKLN +N S Sbjct: 966 DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 1025 Query: 3484 DKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDD 3543 + YK + + + GY LRLDA+P QAAKAS +I SDYKYKE + K G +G+R+++DD Sbjct: 1026 ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1085 Query: 3544 PKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEW 3603 + S++ +QSD YKK FE K +F P+DM +V AKK Q L S+ DYKHPL ++ Sbjct: 1086 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1145 Query: 3604 TCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYR 3663 T L + + A+KA+ LQS+ +Y+SDL ++RG+ V G++E+E K+A E++S+ KYR Sbjct: 1146 TSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYR 1205 Query: 3664 QPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSA 3723 Q K+T +TDTP ++ AK + ++ LY A + + + P+ + AK+N+A Sbjct: 1206 QHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAA 1265 Query: 3724 NISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSI 3783 N+S Y + W + + Y L +A+ ++A+AS DIASD+ Y+ + K++G IG QS+ Sbjct: 1266 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSV 1325 Query: 3784 EDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYL 3843 DDP+I G++QSE +Y++ + +F P+DM+ ++ AK Q L +D DYR Sbjct: 1326 RDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQY 1385 Query: 3844 HEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDS 3903 H++T +P+ + AKKA+ LQS+ YK+DL ++GIGW+ SP++ K A + ++ Sbjct: 1386 HKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISET 1445 Query: 3904 VYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIH---IMPDTPEINL 3960 YR ++K+T++VD+P++V AK++ + + YR D S+H ++PD P+ Sbjct: 1446 KYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTR 1502 Query: 3961 ARANALNVSNKLYREGWDEMKAGC-DVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHY 4019 AR NAL++S+K+YR W++ +AG D RLDAIP Q A+ASREIASD++YK + +G Sbjct: 1503 ARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQ 1562 Query: 4020 VGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDM 4079 +G + DD +++ L +LQ++ EY+ D+AK +++ S D +L +K SQ L SD+ Sbjct: 1563 IGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDV 1622 Query: 4080 DYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAA 4139 YR L Q TC P+Q + A+KA++LQSD YK+DL RG+GW P S V A+ AA Sbjct: 1623 HYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAA 1682 Query: 4140 DI 4141 ++ Sbjct: 1683 EL 1684 Score = 794 bits (2051), Expect = 0.0 Identities = 480/1477 (32%), Positives = 792/1477 (53%), Gaps = 62/1477 (4%) Query: 39 TSDYEQS--ETSKPALAQPA--LAQPASAKPVERRKVIRKKVDPSKFMTPYIAH----SQ 90 T DYEQ + S PA+ PA +A+ A+ + R + + + P I ++ Sbjct: 229 TEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTR 288 Query: 91 KMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHV 150 + D + Y E++E+ +G+ TP + KK + S++KYR D + K H Sbjct: 289 ECADQYGQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHY 347 Query: 151 DE-KAKD---IEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKL 206 A+D ++ A+ V++ VS+V YK++ E ++ + + P+ K + S Sbjct: 348 HSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNK 407 Query: 207 YTEDWEADKSLFYPYNDSPELRRVAQAQKA---LSDVAYKKGLAEQQAQFT-PLADPPDI 262 Y E+++ + Y RR A K S+VAYK + P P Sbjct: 408 YKENYQ--NHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSY 465 Query: 263 EFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQ 322 + A K+ + Y++ + ++TP ++ A++NA +S Y+ D+E K Sbjct: 466 QTAMKLV-PLKDANYRQSIDKLKYSSVTDTP--QIVQAKINAQQLSHVNYRADYEKNKLN 522 Query: 323 IYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDAL 382 Y + + P+ K S+VKYKE +EK KGK L A L KA+G+ Sbjct: 523 -YTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAM---SLLAAKASGELA 578 Query: 383 SDKLYKENYEKTKAKSINYCET-------------------------PKFKLDTVLQNFS 417 S+ YKE YEKTK K++ ++ +F L + N Sbjct: 579 SNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIR 638 Query: 418 SDKKYK----DSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQ 473 KK + D + L Y ED K S+ YKA+ +G G+ + Sbjct: 639 HAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTE 698 Query: 474 TITQEYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESE 533 +A K + Y+ D+ KFT VTDS + A+ + + S + YKA +E Sbjct: 699 GSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQS 758 Query: 534 KFKCHIPPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS 593 + I D P F+Q + NA NLS+ LYK WE KAK F++++D++ LAAKA S Sbjct: 759 VHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLAS 818 Query: 594 DVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETP 653 +V YK+DYE+++GK+IG + D +M HSL+++K QS+ YK+ +E TK++ C Sbjct: 819 EVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQ----CHVS 874 Query: 654 KYQLDTQLKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDK 713 + ++ D+ K H+ D K SD Y+A+ + K Sbjct: 875 LDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMK 934 Query: 714 GKCYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNY 773 G + +A K + + Y+ HPD KFT++ D+P ++QA+++ Q D Y Sbjct: 935 GMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLY 994 Query: 774 KAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAK 833 + + E K AD P+ + ++NA N+S+ YK+ W K + + +++DA+P AAK Sbjct: 995 REQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAK 1054 Query: 834 ANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIY 893 A+ + SD YK+ +EK KG+M+G+ S+ DD + HS+ QSD Y+K +E SK + Sbjct: 1055 ASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQF 1114 Query: 894 TAPLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYN 953 PLDM + AKK+Q +AS+ DYKH L Y+ + + + AKKA+ LQS+ Y++D N Sbjct: 1115 HLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN 1174 Query: 954 SWMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRS 1013 +M+G V G+LE+E K+AS++++E KYRQHP + K+T++ D P + +K + + Sbjct: 1175 -FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITN 1233 Query: 1014 DIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPI 1073 + YKA GE+ H+Y + LP+FI+AK NA N+S+ YK ++L +GY L +A+P Sbjct: 1234 ERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPF 1293 Query: 1074 RAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKT 1133 +AA+A+ ASD Y+ D+ K +GK++G QS++DDP++ H + ++QS+ +Y++ + Sbjct: 1294 QAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSS 1353 Query: 1134 KSKYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYK 1193 +++++ P DM ++V AK AQ + S+ +Y+ H +T LP+ + + +K +QS+ YK Sbjct: 1354 QAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYK 1413 Query: 1194 EDYNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNT 1253 D MKGIGW+ + S +E KKAG+ ++E KYR+ PD++KFT++VDSP +V AK + Sbjct: 1414 SDLIG-MKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSY 1472 Query: 1254 KQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGD 1313 ++ +Y++ + H+YT+ PD P F +A+ NA ++SD Y+ W A + D Sbjct: 1473 MHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLD 1532 Query: 1314 AIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKN 1373 AIP A+ASR IASD++YKEA+ + +G +G+RS+ DDP++ H++NV +LQSD EYKK+ Sbjct: 1533 AIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKD 1592 Query: 1374 YENTKTSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSD 1433 + +++ +H+ D + AK +Q +A++V+Y+QPL T P+ + L H + +Q+QSD Sbjct: 1593 FAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSD 1652 Query: 1434 NVYKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNER 1470 YK + N +G+GW P GS +VE ++A + N R Sbjct: 1653 VKYKSDLN-LTRGVGWTPPGSYKVEMARRAAELANAR 1688 Score = 785 bits (2028), Expect = 0.0 Identities = 504/1535 (32%), Positives = 814/1535 (53%), Gaps = 155/1535 (10%) Query: 1784 YKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKL 1843 Y +E+ + KG A + A+ + +AS +YK+ +++ + F ++ D P+L Sbjct: 157 YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISR---FSTVVDTPEL 213 Query: 1844 VHFMQVAKMQSDREYKKGYEKSKTSFHTPVDML-SVVAAKKSQEVATNANYRNVIHTYNM 1902 + A++QSD Y + YE+ + P + + AK++ E+A++ Y + M Sbjct: 214 LRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQ-YQKEM 272 Query: 1903 LPDAMSFELAKNMMQIQSDNQYKADYADFM---KGIGWLPLGSLEAEKN-KKAMEIISEK 1958 A A+ ++ + +QY Y + +G G P A +N KKA E+ S+ Sbjct: 273 RGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDI 332 Query: 1959 KYRQHPDTLK----YSTLMDSMNMVL--AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQ 2012 KYRQ + +K Y +L N+VL AQ+ K+++E YK+ E+ + + PQ Sbjct: 333 KYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQ 392 Query: 2013 IILAKANAINMSDKLYKLSLEESKKKGYD----LRPDAIPIKAAKASRDIA--SDYK--- 2063 + SD YK + + + Y+ R +K + ++A +DYK Sbjct: 393 FRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDI 452 Query: 2064 --YKY--------------------NYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDRE 2101 Y Y NY + K+ + S+ D P++V + A+ S Sbjct: 453 VDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKL-KYSSVTDTPQIVQAKINAQQLSHVN 511 Query: 2102 YKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHK-----YILLPDAMNIELT 2156 Y+ +YE K +Y P D+ + AK + YK K + + DAM++ Sbjct: 512 YRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 571 Query: 2157 RNMNRIQSDNEYKQDYN---------------------------EWYKGLGWS------P 2183 + + S+ +YK++Y E+ KG S P Sbjct: 572 KASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLP 631 Query: 2184 AGSLEVEKAKKATEYASDQKYRQH----------------------PSNFQFKK------ 2215 + + AKKA ASD YR+ S Q+K Sbjct: 632 MDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMK 691 Query: 2216 ----LTD-SMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQK 2270 LT+ S+++ AK+ +++ Y D+ K + D+ + AK++Q L S Sbjct: 692 GVGWLTEGSLNLEQAKKAGQLVSEKNYR--QRVDELKFTSVTDSSQMEHAKKSQELQSGV 749 Query: 2271 LYKLGWEEAL-----------------------------------KKGYDLPVDAISVQL 2295 YK G E+++ KG++L +D+++ Sbjct: 750 AYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLA 809 Query: 2296 AKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKT 2355 AKA RD+AS+ KYK+ Y + G +G + +Q D ++ S+ ++K+QSE EYKK FE K+ Sbjct: 810 AKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKS 869 Query: 2356 KFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSD 2415 + +DM+ +V A+K Q L +DV YK H +T LP V AKK Y LQS+N Y++D Sbjct: 870 QCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRAD 929 Query: 2416 LEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNR 2475 ++W++G+GW GSL E+ K+A E+ISEKKYRQ PD KFTSI D ++V A+ + Sbjct: 930 VKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQA 989 Query: 2476 SDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIP 2535 DRLYRE + K D P+++LAK N +N S+ Y+ + +L+ GY L +DA+P Sbjct: 990 VDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALP 1049 Query: 2536 IKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEK 2595 +AAKAS EI S+YKYKE F K G +G+R++EDD + S++ +QSD YKK FE Sbjct: 1050 FQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEH 1109 Query: 2596 WKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNLY 2655 K +F P+DM +V AKK QTL S+ DYK+ L Q+T L + + A++A+ LQS+NLY Sbjct: 1110 SKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLY 1169 Query: 2656 KSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLAKNNA 2715 +SDL +++G+ + G+LE E K+A++++S+ YRQHP FK++++ D+ ++ AK + Sbjct: 1170 RSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSN 1229 Query: 2716 ITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVD 2775 N RLY A + + + PE + AK N N S+ YK + +GY + ++ Sbjct: 1230 QITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIE 1289 Query: 2776 AIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKD 2835 A+P +AA+AS DIAS+F Y+ + K+ G IG +++RDDP++ + ++QS+ +Y++ Sbjct: 1290 ALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRG 1349 Query: 2836 FEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSD 2895 + +F P+DM+ +V AK Q L SD DY+ H++T LP+ + A++A+ LQS+ Sbjct: 1350 ATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSE 1409 Query: 2896 NMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAK 2955 YKSDL M+GIGW+++ S +E K+A E++S+ YR+ PD KFT+V DS + V AK Sbjct: 1410 LRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAK 1469 Query: 2956 NNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDL 3015 N+ ++ N+R+Y + + ++PD P+ AR N ++ S+ +Y+ + E+ + YD Sbjct: 1470 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1529 Query: 3016 RSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREY 3075 R DAIP A+ASR++ SD++YK+ + + G IG R+++DDP+M ++V ++QSD EY Sbjct: 1530 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1589 Query: 3076 KKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDL 3135 KKDF K +++F S D G++ AK+ Q L SDV Y+ L + TC P+Q + HA++A+ L Sbjct: 1590 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQL 1649 Query: 3136 QSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEI 3170 QSD YKSDL RG+GW P GS V +RAAE+ Sbjct: 1650 QSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1684 Score = 754 bits (1948), Expect = 0.0 Identities = 482/1553 (31%), Positives = 809/1553 (52%), Gaps = 73/1553 (4%) Query: 3363 LPDQNDI--IHARKAYDLQSDNLYKSDLEWMKGIGWVP-IDSLEVVRAKRAGELLSDTIY 3419 LPD + + ARK+ + Y D E +G G P + + RAK+A +L S Y Sbjct: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193 Query: 3420 RQRPETL--KFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAK 3476 ++ + +F+++ DTPE + +K A + YTE ++ + K TP +AK Sbjct: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAK 253 Query: 3477 -----LNRINYSDKL-----------------------------YKLALEESKKEGYDLR 3502 + + Y + Y EE + +G Sbjct: 254 RANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPA 313 Query: 3503 LDAIPIQAAKASRDIASDYKYKEGYRKQLGH-HIGARNIKDDPKMMWSIHVAKIQSDREY 3561 + Q AK + ++ASD KY++ + K G H + +D+ + + V K+ S+ EY Sbjct: 314 MITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEY 373 Query: 3562 KKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYK-----HPLHEWTCLPDQNDVIQAR 3616 KK+ E + + + K SD YK H + + + A Sbjct: 374 KKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAM 433 Query: 3617 KAYDLQSDAIYKSD-----LEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKF 3671 K L S+ YK+D +++ P ++ V L D YRQ D+LK+ Sbjct: 434 KVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVP-----LKDANYRQSIDKLKY 488 Query: 3672 TCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYT 3731 + +TDTP+IV AK NA +S Y ++ +K + + D P ++ AK+N+ S+ Y Sbjct: 489 SSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYK 548 Query: 3732 KGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMC 3791 +GW+++K K ++++ DA+S+ +AKAS ++AS+ KYKE YEK KG +G D +++ Sbjct: 549 EGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLH 604 Query: 3792 AIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPD 3851 ++ K+ SE EYKK F++ KT+F P+DM++I AKK QTL +D+DYR LHE+T +P+ Sbjct: 605 SLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPE 664 Query: 3852 QNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDSVYRTPVVN 3911 AKKAY LQS+ YKADL W++G+GW+ +GS + + K A + + YR V Sbjct: 665 DMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDE 724 Query: 3912 LKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINLARANALNVSNK 3971 LK+TS+ D+ ++ AK + E S Y+ ++ I D P ARANA N+S K Sbjct: 725 LKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEK 784 Query: 3972 LYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDNK 4030 LY+ W+ KA G ++RLD++ AAKA R++AS+ KYK D+E+ +G +G + D++ Sbjct: 785 LYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQ 844 Query: 4031 IRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYLHQWTC 4090 + +L KLQ+E EY+ + K++ +DM+ ++H++ +Q L +D+ Y+ H +T Sbjct: 845 MSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTA 904 Query: 4091 MPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTK 4150 +P V AKKAY LQSDN Y+AD++W++G+GW+ S++V AK A ++ SEKKYR Sbjct: 905 LPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQH 964 Query: 4151 IETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLT-ETPLLHTAQEAARIL 4209 + L FT + D + V A+ S D YR+ K YT T + P + A+ A + Sbjct: 965 PDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNI 1024 Query: 4210 DQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRD 4269 + YKE W + + GY L DA+PF A ++ S+ KYK K KG +G ++ D Sbjct: 1025 SETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLED 1084 Query: 4270 DPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNYLHQ 4329 D L +A +Q++ YK+ + +KA+ ++P DM +++ AK+ QTL S+ DY++ L Q Sbjct: 1085 DISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQ 1144 Query: 4330 WMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKNQEMMSQIKY 4389 + + + A+KA+ LQS+N+YR+DL ++RG+ + +++ K E++S+ KY Sbjct: 1145 YTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKY 1204 Query: 4390 KKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKD 4449 +++ + + +V D P ++ AK ++ ++ YK A+ +YT + P +K Sbjct: 1205 RQH--PHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKT 1262 Query: 4450 MGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAG 4509 S YK +W +A GY L +P A+ + + S+ Y+ + K++G + Sbjct: 1263 NAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGP 1322 Query: 4510 KVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYR 4569 + + + P + HC +++S L YR+ ++A H+P DM++ V AK Q + SD +YR Sbjct: 1323 QSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYR 1382 Query: 4570 HYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQ 4629 +H++T+L E+ + + A + S+ YK DL +KGIG +PQ+ AKK+ +L Sbjct: 1383 TQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELI 1442 Query: 4630 SQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDY 4689 S+ +Y K + + V D+P V A S ++ +E Y+ + +YT + + D+ Sbjct: 1443 SETKYRK--KPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1500 Query: 4690 DRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKA 4749 R R S +Y+ +W++ +A SY + A+ + +AS +Y+E + + + Sbjct: 1501 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1560 Query: 4750 LYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVS 4809 L RSVDDDP L VG+L D Y+ + K++ + H D ++ AK SQ+ S Sbjct: 1561 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1620 Query: 4810 EIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTP 4862 ++ YR L + C P+ H +K SD+ YK DLN +G+G W P Sbjct: 1621 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVG---WTPP 1670 Score = 641 bits (1654), Expect = 0.0 Identities = 469/1628 (28%), Positives = 772/1628 (47%), Gaps = 210/1628 (12%) Query: 3057 DPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQTLVSDVDYKN--- 3112 DP+++ + K + EY +D+E+ + K S P + AKK L S V+YK Sbjct: 140 DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198 Query: 3113 -YLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVK-CKRAAEI 3170 + ++ + D +++ ++ LQSD Y D + RG G P + KRA E+ Sbjct: 199 ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANEL 258 Query: 3171 LSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIM 3230 SD Y Q + K+ + E + Sbjct: 259 ASDVRYHQQ---------------------------------YQKEMRGMAGPAIGAEGI 285 Query: 3231 LARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGH 3290 L R+ Y + Y + EE + +G AK + ++ASD KY++ + K G Sbjct: 286 LTRECADQYGQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGA 344 Query: 3291 -HIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVS 3349 H + D+ + + + K+ S+ EYKKD E + + + K S Sbjct: 345 AHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTS 404 Query: 3350 DVDYK-----HPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEV 3404 D YK H + + +HA K L S+ YK+D + P Sbjct: 405 DNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPS 464 Query: 3405 VRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIH 3464 + L D YRQ + LK++S+TDTP+ V AK NA ++ Y ++ +K Sbjct: 465 YQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYT 524 Query: 3465 VMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYK 3524 + D P+++ AK N +S+ YK E++K +G++++LDA+ + AAKAS ++AS+ KYK Sbjct: 525 LPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 584 Query: 3525 EGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLA 3584 E Y K G +G D +++ S+ +AK+ S+ EYKK FE+ KT+F P+DM+ + A Sbjct: 585 EEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHA 640 Query: 3585 KKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGS 3644 KK Q L SD+DY+ LHE+T LP+ A+KAY LQS+ YK+DL W++G+GW+ GS Sbjct: 641 KKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGS 700 Query: 3645 VEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKT 3704 + +E+ K+AG+++S++ YRQ D+LKFT +TD+ ++ AK + S Y + Sbjct: 701 LNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVH 760 Query: 3705 SIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDY 3764 + D P L A++N+AN+S+KLY W+ K K ++LR D+++ +AKA RD+AS+ Sbjct: 761 QYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEV 820 Query: 3765 KYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSI 3824 KYKE YE+ +G IGA+ ++ D ++ ++ K+QSE EYKK F+ K++ +DM+ + Sbjct: 821 KYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHL 880 Query: 3825 LLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMP 3884 + A+K Q L TD+ Y+ H +T +P + AKKAY LQSD Y+AD++W++G+GW+ Sbjct: 881 VHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 940 Query: 3885 QGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDK 3944 GS V + K A + + YR LK+TSI DTPE+V A+ + YRE + Sbjct: 941 TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGEN 1000 Query: 3945 DKTSIHIMPDTPEINLARANALNVSNKLYREGWDEMK-AGCDVRLDAIPIQAAKASREIA 4003 K D PE+ LA+ NA+N+S Y+E W +++ G +RLDA+P QAAKAS EI Sbjct: 1001 IKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEII 1060 Query: 4004 SDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDM 4063 SDYKYK EK KG +G+ + DD + ++ A LQ++ Y+ + KA+ P+DM Sbjct: 1061 SDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDM 1120 Query: 4064 LSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIG 4123 +++H+K +Q L S+ DY++ L Q+T + + + AKKA++LQS+N+Y++DL ++RG+ Sbjct: 1121 AALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVA 1180 Query: 4124 WM---------------------------------PNDSVSVNHAKHAADIFSEKKYRTK 4150 + D+ ++ HAK + I +E+ Y+ Sbjct: 1181 CVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAA 1240 Query: 4151 IETLN--FTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSK-YTLTETPL-LHTAQEAA 4206 E +T +++ AK + L D +Y++ W +++ Y LT L A+ + Sbjct: 1241 GEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASG 1300 Query: 4207 RILDQYLYKEGW--ERQKATG-----------------------------------YILP 4229 I +LY+ + ER K G + LP Sbjct: 1301 DIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLP 1360 Query: 4230 PDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYK 4289 D V VHA + + S+ Y+ ++ K + +P +D K+ W + A +Q+E YK Sbjct: 1361 MDMVHLVHAKNAQALASDHDYRTQYHK----FTALP---EDLKMAWAKKAHALQSELRYK 1413 Query: 4290 EDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNY----------------------- 4326 D K + + +AK+ L+S+ YR Sbjct: 1414 SDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYM 1473 Query: 4327 --------------LHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGW-IPLDS 4371 LH++ PD D +AR SD VYR E R + LD+ Sbjct: 1474 HCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDA 1533 Query: 4372 VDHVRVTKNQEMMSQIKYKKNALENYP---NFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428 + ++E+ S +YK+ L + +RSV D P + QSD +YK+ F Sbjct: 1534 IPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDF 1593 Query: 4429 NKAKGKYTFSPDTPHI-------------------------------SHSKDMGKLYSTI 4457 K++ ++ S D P + H++ +L S + Sbjct: 1594 AKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDV 1653 Query: 4458 LYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNS-----ELKYKETYEKQKGHYLAGKVI 4512 YK T+ G+T Y + + A+L N+ + Y+ + G + +G+V Sbjct: 1654 KYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQSGEVN 1713 Query: 4513 GEFPGVVH 4520 + ++H Sbjct: 1714 PDATEILH 1721 Score = 626 bits (1614), Expect = e-178 Identities = 454/1550 (29%), Positives = 754/1550 (48%), Gaps = 124/1550 (8%) Query: 3647 VEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSI 3706 VE K GE ++ Y QP + F + TP AK S+ Y D + Sbjct: 147 VEARKSLGEEYTE-DYEQPRGKGSFPAMI-TPAYQRAKKANQLASQVEYKRGHDERISRF 204 Query: 3707 HVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKY 3766 + DTP++L +K+ + S YT+ +++ + K + + AK + ++ASD +Y Sbjct: 205 STVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRY 264 Query: 3767 KEAYEKQ----KGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDML 3822 + Y+K+ G IGA+ I CA G + Y +E+++ + K S P + Sbjct: 265 HQQYQKEMRGMAGPAIGAEGILTRE---CADQYG-----QGYPEEYEEHRGKGSFPAMIT 316 Query: 3823 -SILLAKKCQTLVTDIDYRNYLHE------WTCMPDQNDII--QAKKAYDLQSDALYKAD 3873 + AKK L +DI YR ++ + +P Q++++ QA+ L S+ YK D Sbjct: 317 PAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKD 376 Query: 3874 LEWLRGIGWMPQGSPEVLRVKN-------------------------------------- 3895 LE RG +P+ V Sbjct: 377 LESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVG 436 Query: 3896 --AQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMP 3953 A N+ + Y+ +V+ Y + + TP A + YR+ DK K S + Sbjct: 437 SLASNVAYKADYKHDIVDYNYPATL-TPSYQTAMKLVP-LKDANYRQSIDKLKYS--SVT 492 Query: 3954 DTPEINLARANALNVS----------NKL-------------------------YREGWD 3978 DTP+I A+ NA +S NKL Y+EGW+ Sbjct: 493 DTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWE 552 Query: 3979 EMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIA 4037 + K G +++LDA+ + AAKAS E+AS+ KYK ++EK KG +GT D+++ +L Sbjct: 553 KTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQI 608 Query: 4038 DKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDV 4097 K+ +E EY+ + + K + P+DM++I H+K +Q L SD+DYR LH++T +P+ Sbjct: 609 AKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKT 668 Query: 4098 IQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFT 4157 AKKAY LQS+ YKADL W++G+GW+ S+++ AK A + SEK YR +++ L FT Sbjct: 669 QWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFT 728 Query: 4158 PVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLT-ETPLLHTAQEAARILDQYLYKE 4216 V D AK+S E+ + Y+ + +YT++ + PL A+ A L + LYK Sbjct: 729 SVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKS 788 Query: 4217 GWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWF 4276 WE QKA G+ L D++ F+ A D+ SE+KYK ++ + +G +G ++ D ++ Sbjct: 789 SWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHS 848 Query: 4277 EHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQ 4336 ++Q+E YK+ + TK++ ++ DMV ++ A++ Q L +D+ Y+ H + P Sbjct: 849 LQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTD 908 Query: 4337 NDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKNQEMMSQIKYKKNALEN 4396 V A+KAY LQSDN YRAD++W++G+GW+ S++ + K E++S+ KY+++ + Sbjct: 909 MKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQH--PD 966 Query: 4397 YPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYST 4456 F S+ D PE+V A+I+ D Y+E K YT + D P + +K S Sbjct: 967 ALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISE 1026 Query: 4457 ILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFP 4516 YK +W + GY L +P AK + + S+ KYKE +EK KG L + + + Sbjct: 1027 TRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDI 1086 Query: 4517 GVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWT 4576 + H + ++S +NY+K +E +KA H+P DM V AK+ Q + S+ +Y+H Q+T Sbjct: 1087 SLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYT 1146 Query: 4577 SLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTA 4636 SL E+ + + A ++ S+N+Y+ DLN+++G+ C + T +I KK+ +L S+ +Y Sbjct: 1147 SLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ 1206 Query: 4637 AGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLK 4696 + Y VTDTP + A S +E YK + +YT L ++ R + Sbjct: 1207 --HPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNA 1264 Query: 4697 NLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRS 4756 S YKE+W ++A Y L L A+ +AS YR ++ K + P+S Sbjct: 1265 ANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQS 1324 Query: 4757 VDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLR 4816 V DDP C R+G+L + YR ++ + H+ DMV +V AK++Q S+ DYR + Sbjct: 1325 VRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQ 1384 Query: 4817 LHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDD 4876 H++ P+ +K S++ YK DL +KGIG +P++ AK A +L + Sbjct: 1385 YHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISE 1444 Query: 4877 IKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLD 4936 KY+ + + V D+P V A S ++ +Y S+ + D Sbjct: 1445 TKYRKKPDSIK--FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLH-RYTLIPDHPDFT 1501 Query: 4937 RA-LHAYKLQSSNLYKTSLRTLPTG-YRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKA 4994 RA L+A L S +Y+ S G Y D F+ + +R ++S F+YKEA+ + Sbjct: 1502 RARLNALHL-SDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1560 Query: 4995 --YGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVS 5052 GY D H V + S+ Y++ + K + + H++ D P + Q K++Q+ S Sbjct: 1561 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1620 Query: 5053 ELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFG 5102 ++ Y+ P + H + + SD+KYK DL + +G G Sbjct: 1621 DVHYRQPL----PQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVG 1666 Score = 438 bits (1127), Expect = e-122 Identities = 404/1585 (25%), Positives = 701/1585 (44%), Gaps = 114/1585 (7%) Query: 4045 EYRLDWAKWKAKIQSPVDML-SILHSKNSQALVSDMDYRN----YLHQWTCMPDQNDVIQ 4099 EY D+ + + K P + + +K + L S ++Y+ + +++ + D ++++ Sbjct: 156 EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLR 215 Query: 4100 AKKAYELQSDNVYKADLEWLRGIGWMPND-SVSVNHAKHAADIFSEKKYRTKIETLN--- 4155 +K +LQSD Y D E RG G P + + AK A ++ S+ +Y + + Sbjct: 216 SKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGM 275 Query: 4156 FTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLHTAQEAARILDQYLYK 4215 P +T + + + + + K + TP A++A + Y+ Sbjct: 276 AGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYR 335 Query: 4216 EGWERQKATGYI--LPP-DAVPFVHAHHCNDVQSELKYKAEHVKQKGH---YVGVPTMRD 4269 + + + K + LP D + A N + SE++YK + +GH Y P R+ Sbjct: 336 QDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRN 395 Query: 4270 DPKLVWFEHAGQIQNERLYKEDY--HKTKAKINIPADMVSVLAAKQGQTLVSDIDYR-NY 4326 K+ F ++ YKE+Y H + D ++ A K G +L S++ Y+ +Y Sbjct: 396 VSKISKFT------SDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVG-SLASNVAYKADY 448 Query: 4327 LHQWMCHPDQNDVIQARKAYDLQSDNVYRADL--EWLRGIGWIPLDSVDHVRVTKNQEMM 4384 H D++ D Y A L + + +PL ++ ++ + Sbjct: 449 KH---------DIV----------DYNYPATLTPSYQTAMKLVPLKDANY------RQSI 483 Query: 4385 SQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHI 4444 ++KY SV D P+IV AKIN+ S V Y+ + K K YT D P + Sbjct: 484 DKLKYS-----------SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQL 532 Query: 4445 SHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKG 4504 +K KL+S + YK WE TK G+ + + ++ AK + + S +KYKE YEK KG Sbjct: 533 VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 592 Query: 4505 HYLAGKVIGEFPG-VVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYIL 4563 K +G ++H L KM S + Y+K +E++K H+P DM+N AK+ Q + Sbjct: 593 -----KAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 647 Query: 4564 SDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAK 4623 SDL+YR H++T L E+ + A + S+ YK DL W+KG+G + + AK Sbjct: 648 SDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAK 707 Query: 4624 KSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTV 4683 K+ L S+ Y E + VTD+ A +S S V YK Q +YT Sbjct: 708 KAGQLVSEKNYRQRVDE--LKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTIS 765 Query: 4684 LETVDYDRTR-NLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYRE 4742 + + + R N NL S LYK +W+ KA + L +L+ AK ++ LAS +KY+E Sbjct: 766 KDEPLFLQARANAANL-SEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKE 824 Query: 4743 EYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAK 4802 +YE+ + + V D + L++ KL + Y+ +E K + H+ DMV +V A+ Sbjct: 825 DYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHAR 884 Query: 4803 DSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTP 4862 +Q +++ Y+ H + P + +K SD Y+ D+ W+KG+G + Sbjct: 885 KAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSL 944 Query: 4863 EILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSV 4922 + AK A +L + KY+ H + + + DTP VQA S Q D +Y + ++ Sbjct: 945 NVEQAKKAGELISEKKYRQHPDALK--FTSIKDTPEMVQARISYTQAVDRLYR-EQGENI 1001 Query: 4923 RGKVAPTTKTVDLDRALHAYKLQSSNL----YKTSLRTL-PTGYRLPGDTPHFKHIKDTR 4977 + P T DL L A KL + N+ YK S L GY+L D F+ K + Sbjct: 1002 KHHYTP---TADLPEVLLA-KLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASG 1057 Query: 4978 YMSSYFKYKEAYEHTKAYGYTLGPK----DVPFVHVRRVNNVTSERLYRELYHKLKDKIH 5033 + S +KYKEA+E K G LG + D+ H ++ S+ Y++ + K + H Sbjct: 1058 EIISDYKYKEAFEKMK--GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1115 Query: 5034 TTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKE 5093 D + KK Q S YK SL ++ + + S+ Y+ Sbjct: 1116 LPLDMAALVHAKKAQTLASNQDYKHPL----PQYTSLAEDLRLSCAKKAHKLQSENLYRS 1171 Query: 5094 DLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELK 5153 DL ++G C + T ++ + +L S Y KY V DTP + Sbjct: 1172 DLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSF--KYTAVTDTPNLLHAKFSN 1229 Query: 5154 THLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQ 5212 +E +Y+AAG+ + +T P+ +RAK S Y E R + + Sbjct: 1230 QITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIE 1289 Query: 5213 TTALKHAKDVKDMVSEKKYKIQYEKMKDKY---TPVPDTPILIRAKRAYWNASDLRYKET 5269 + A+ D+ S+ Y+ + K + K V D P + +R S+L+Y+ Sbjct: 1290 ALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRG 1349 Query: 5270 FQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTD 5329 ++ ++H D + +V+ + + + +Y +Q + ++P+ + + Sbjct: 1350 ATSSQAQFHLPMDMVHLVHAK----NAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHA 1405 Query: 5330 TVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSP 5389 S+++YK DL +KGIG A +P A+K L S+ KY++ + K F V DSP Sbjct: 1406 LQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIK--FTTVVDSP 1463 Query: 5390 INRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSK 5449 H K + NE+ YR+ + +Y L+ D P A+ +S YR ++E+++ Sbjct: 1464 DLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTR 1523 Query: 5450 DKFTSIVDTPEHLRTTKVNKQI-SDILYKLEY--NKAKPRGYTTIHDTPMLLHVRKVKDE 5506 +T + +++I SD YK + ++ GY ++ D P + H V Sbjct: 1524 AGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRL 1583 Query: 5507 VSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPD 5566 SD +YK+ + +++S D + AK + ++ +++ Y++ P++ Sbjct: 1584 QSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTC----DPEQLG 1639 Query: 5567 FLQAAKSSLQQSDFEYKLDREFLKG 5591 A K+ QSD +YK D +G Sbjct: 1640 LRHAQKAHQLQSDVKYKSDLNLTRG 1664 Score = 409 bits (1051), Expect = e-113 Identities = 404/1636 (24%), Positives = 714/1636 (43%), Gaps = 200/1636 (12%) Query: 4334 PDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIP-LDSVDHVRVTKNQEMMSQIKYKKN 4392 P+ +++ARK+ + Y D E RG G P + + + R K ++ SQ++YK+ Sbjct: 141 PEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196 Query: 4393 ALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTF-SPDTPHISHSKDMG 4451 E F +VVD PE++ +K + QSDV+Y E + + +GK +F + TP +K Sbjct: 197 HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRAN 256 Query: 4452 KLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELK------YKETYEKQKGH 4505 +L S + Y + Y + P +GA+ ++ E Y E YE+ +G Sbjct: 257 ELASDVRYH------QQYQKEMRGMAGPAIGAE--GILTRECADQYGQGYPEEYEEHRGK 308 Query: 4506 YLAGKVIGEFPGVV-----HCLDFQKMRSALNYRKHYEDTKANVHIPN-DMMNHVLAKRC 4559 G FP ++ + ++ S + YR+ + K H + ++++ K+ Sbjct: 309 -------GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQA 361 Query: 4560 QYI---LSDLEYRHYFHQWT----SLLEEPNVIRVRNAQEILSDNVYKDDL-NWLKGIGC 4611 Q + +S++EY+ + E P V + SDN YK++ N ++G Sbjct: 362 QSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYE 421 Query: 4612 YVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNL-VTDTPLYVTA------------- 4657 V + LHA K L S + Y A K ++ +YN T TP Y TA Sbjct: 422 GVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQ 481 Query: 4658 ----------------VQSGINA---SEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNL 4698 VQ+ INA S V Y+ +Y + K YT + + + L Sbjct: 482 SIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKL 541 Query: 4699 YSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFK--ALYTLPRS 4756 +S YKE W++ K + + +SL AK LAS+IKY+EEYEK K A+ T Sbjct: 542 FSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA--- 598 Query: 4757 VDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLR 4816 D L++ K++ + Y+ +E++K + H+ DMV + AK +Q S++DYR + Sbjct: 599 ---DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKK 655 Query: 4817 LHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDD 4876 LHE+ P+ +K S++ YK DL W+KG+G + + AK A L + Sbjct: 656 LHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSE 715 Query: 4877 IKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLD 4936 Y+ + + + + VTD+ A KS + S Y SV + + L Sbjct: 716 KNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQ 773 Query: 4937 RALHAYKLQSSNLYKTSLRTLPT-GYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAY 4995 +A L S LYK+S G+ L D+ F K R ++S KYKE YE ++ Sbjct: 774 ARANAANL-SEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSR-- 830 Query: 4996 GYTLGPKDVP----FVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAV 5051 G +G KDV H +++ + SE Y++ + K + H + D + +K Q Sbjct: 831 GKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLA 890 Query: 5052 SELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDM 5111 +++ YK+ + H +LP +V + + SD +Y+ D++ +KG G + ++ Sbjct: 891 TDVGYKT----AEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNV 946 Query: 5112 VRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSI 5171 +++ +L S Y + K+ + DTPE + + T + +YR G+ K Sbjct: 947 EQAKKAGELISEKKYRQHPDAL--KFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH 1004 Query: 5172 FTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKK 5230 +T D P++L AK S+ Y E +K R + + AK +++S+ K Sbjct: 1005 YTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYK 1064 Query: 5231 YKIQYEKMKDKYT---PVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIV 5287 YK +EKMK + + D L + A SD+ YK+ F+ +K ++H D +V Sbjct: 1065 YKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALV 1124 Query: 5288 YHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG 5347 + +K S YK + + H+ ++ + Y+ DL +++G+ Sbjct: 1125 HAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENL----YRSDLNFMRGVA 1180 Query: 5348 CYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVA--DSPINRHFKYATQLMNEKK 5405 C T + +K L S+ KY++ FKY A D+P H K++ Q+ NE+ Sbjct: 1181 CVIPGTLEIEGRKKASELISESKYRQ----HPHSFKYTAVTDTPNLLHAKFSNQITNERL 1236 Query: 5406 YRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTT 5465 Y+A E + +Y + + P + AKT +S +Y++++ + + + + Sbjct: 1237 YKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAA 1296 Query: 5466 KVNKQI-SDILYKLEYNKAKPR--GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSN 5522 + + I SD LY+ ++ K + + G ++ D P + H R++ S+L+Y+ +++ Sbjct: 1297 RASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQ 1356 Query: 5523 CTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEY 5582 + D VH+ AK+A + ++ DY+ QY A P+ A K+ QS+ Y Sbjct: 1357 FHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTA----LPEDLKMAWAKKAHALQSELRY 1412 Query: 5583 KLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKT 5642 K D +KG A + + S+ KY++K + T V D+P ++ AK Sbjct: 1413 KSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFT--TVVDSPDLVHAKN 1470 Query: 5643 VSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT--------------- 5687 +E Y+ + L + YT +P+ D + H+SD Sbjct: 1471 SYMHCNERMYRSGDAESLHR--YTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYD 1528 Query: 5688 ---------------------NYKKKFVKEKG-KSNYSIMLEPPEVKHAMEVAKKQSDVA 5725 YK+ F++++G + Y + + P +KH + V + QSD Sbjct: 1529 FRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNE 1588 Query: 5726 YRKD-AKENLHYTTVADRPDIKKATQAAKQASEVEYRA--------------KHRKEGSH 5770 Y+KD AK + + D+P + +A ++ + AS+V YR +H ++ Sbjct: 1589 YKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQ 1648 Query: 5771 -----------------GLSMLGRPDIEMAKKAAKLSS------QVKYRENFDKEKG--K 5805 G + G +EMA++AA+L++ Q YR E G + Sbjct: 1649 LQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQ 1708 Query: 5806 TPKYNPKDSQLYKVMK 5821 + + NP +++ V K Sbjct: 1709 SGEVNPDATEILHVKK 1724 Score = 348 bits (892), Expect = 1e-94 Identities = 385/1558 (24%), Positives = 678/1558 (43%), Gaps = 103/1558 (6%) Query: 4651 TPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDR 4710 TP Y A ++ AS+V+YK + + +++TV++T + R++ L S Y E +++ Sbjct: 175 TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ 234 Query: 4711 VKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVG 4770 + T + AK LAS ++Y ++Y+K P + T C Sbjct: 235 QRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECAD-- 292 Query: 4771 KLNIDRLYRSVYEKNKMKIHIVPDMVEMV--TAKDSQKKVSEIDYRLRLHEW-------- 4820 + Y YE+++ K P M+ AK + + S+I YR ++ Sbjct: 293 --QYGQGYPEEYEEHRGK-GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHS 349 Query: 4821 ICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYK 4880 + D V + V +S++ YK DL +G +TP+ + D KYK Sbjct: 350 LPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYK 409 Query: 4881 A-HMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRAL 4939 + R Y+ V + A+K G S+ Y DY H + P T T A+ Sbjct: 410 ENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAM 469 Query: 4940 HAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTL 4999 L+ +N Y+ S+ L Y DTP K S+ Y+ YE K YTL Sbjct: 470 KLVPLKDAN-YRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTL 525 Query: 5000 GPKDVPFVHVRRVN-NVTSERLYRELYHKLKDK-IHTTPDTPEIRQVKKTQEAVSELIYK 5057 P+DVP + + N + SE Y+E + K K K D + K + E S + YK Sbjct: 526 -PQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 584 Query: 5058 SDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHL 5117 ++ K +G + +++H + ++S+++YK+ + K + DMV RH Sbjct: 585 EEYEKTKGKAMGTA-DSRLLHSLQIAKMSSEVEYKKGFEESK---TRFHLPMDMVNIRHA 640 Query: 5118 RKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHL---SELVYRAAGKKQKSIFTS 5174 +K + D +K+ + Y V+ PE K Q K SEL Y+A K + Sbjct: 641 KKAQTLASDLDYRKKLHE-YTVL---PEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWL 696 Query: 5175 VPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAKDVKDMVSEKKYKIQ 5234 + +L +AK+ +L S+ Y + + + + ++ ++HAK +++ S YK Sbjct: 697 TEGSLNLEQAKKAGQLVSEKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAG 754 Query: 5235 YEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVK-DALDIVYHRKVT 5293 E+ +YT D P+ ++A+ N S+ YK +++ K K ++ D+L + + Sbjct: 755 NEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKR 814 Query: 5294 DDISKIKYKENYMSQLGIW---RSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYA 5350 D S++KYKE+Y G + + + H ++ S+++YK+ K + Sbjct: 815 DLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVS 874 Query: 5351 YDTPDFTLAEKNKTLYSKYKYKEV---FERTKSDFKYVADSPINRHFKYATQLMNEKKYR 5407 D A K + L + YK F +D K K A L ++ +YR Sbjct: 875 LDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKV-------EWAKKAYGLQSDNQYR 927 Query: 5408 ADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKV 5467 AD + K + AK AG+ IS+ KYR++ + KFTSI DTPE ++ Sbjct: 928 ADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDAL--KFTSIKDTPEMVQARIS 985 Query: 5468 NKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQR-NKSNCTIE 5526 Q D LY+ + K YT D P +L + +S+ +YKE + + + Sbjct: 986 YTQAVDRLYREQGENIK-HHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLR 1044 Query: 5527 PDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKS---SLQQSDFEYK 5583 DA+ +AAK + ++ ++ YK+ +E K + D + A S + QSD YK Sbjct: 1045 LDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYK 1104 Query: 5584 LDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTV 5643 E K D V A + + S+ Y KH + T ++ + ++ AK Sbjct: 1105 KGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDY--KHPLPQYT--SLAEDLRLSCAKKA 1160 Query: 5644 SNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYS 5703 L SEN Y+ + + +G +P T + K+ ++ +S++ Y+ + Y+ Sbjct: 1161 HKLQSENLYRSDL--NFMRGVACVIPGTLEIEGRKKASELISESKYR----QHPHSFKYT 1214 Query: 5704 IMLEPPEVKHAMEVAKKQSDVAYRKDAKENLH-YTTVADRPDIKKATQAAKQASEVEYRA 5762 + + P + HA + ++ Y+ ++ H YT P+ +A A S+ Y+ Sbjct: 1215 AVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKE 1274 Query: 5763 KHRKEGSHGLSM-LGRPDIEMAKKAAKLSSQVKYRENFDKEKGK-TPKYNPKDSQLYKVM 5820 R + G + + + A+ + ++S YR +F KE+GK + +D + Sbjct: 1275 SWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHC 1334 Query: 5821 KDANNLASEVKYK----ADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKG 5876 + L SE++Y+ + + H P+ + + + H N LAS + Y+ +Y K Sbjct: 1335 RRMGQLQSELQYRRGATSSQAQFHLPM----DMVHLVHAKNAQALASDHDYRTQYHK--- 1387 Query: 5877 HYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKE 5936 + +P++L+ K+A LQS ++YK +G L +P +AK++ ++ S + Sbjct: 1388 -FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETK 1446 Query: 5937 YRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDM 5996 YRK +SIK T + +P L+H K + +E+ YR ES+ T + D PD Sbjct: 1447 YRKK-PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLH--RYTLIPDHPDF 1500 Query: 5997 LRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEME 6056 RA+ L++K Y+ E + + + + P F AR + +IAS +YK++ + Sbjct: 1501 TRARLNALHLSDKVYRNSWE-QTRAGSYDFRLDAIP-FQTARASREIASDFRYKEAFLRD 1558 Query: 6057 KA---NFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKN 6113 + + SV D P + H V L S +YK+D KS S + + D P + + + +Q+ Sbjct: 1559 RGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQL 1618 Query: 6114 FSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNF---SSVLYKEDVSPGTAIGKTP 6168 S + Y+ L PE L ++ QK S V YK D++ +G TP Sbjct: 1619 ASDVHYRQPLPQP-------TCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTP 1669 Score = 338 bits (866), Expect = 1e-91 Identities = 402/1677 (23%), Positives = 712/1677 (42%), Gaps = 184/1677 (10%) Query: 3726 SQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIED 3785 +++ Y G+ E D ++ +A + + +Y E YE+ +G G+ Sbjct: 119 NERAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYT--EDYEQPRGK--GSFPAMI 174 Query: 3786 DPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHE 3845 P A A ++ S+ EYK+ + ++FS+ VD +L +K L +D+ Y + Sbjct: 175 TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ 234 Query: 3846 WTCMPDQNDIIQ-----AKKAYDLQSDALYKADLE-WLRGIGWMPQGSPEVLRVKNAQNI 3899 +I AK+A +L SD Y + +RG+ G+ +L + A Sbjct: 235 QRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294 Query: 3900 --FCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHI--MPDT 3955 Y + +++ TP AK E S KYR+ ++K K + H +P Sbjct: 295 GQGYPEEYEEHRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353 Query: 3956 PEINLARANALN--VSNKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHE 4013 + L +A ++N VS Y++ + + + + + SD KYK +++ Sbjct: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQ 413 Query: 4014 K-QKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNS 4072 +G Y G D + A+ L + Y+ D+ P + + Sbjct: 414 NHMRGRYEG---VGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMK 470 Query: 4073 QALVSDMDYRNYLH--QWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSV 4130 + D +YR + +++ + D ++QAK + S Y+AD E + +P D Sbjct: 471 LVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVP 530 Query: 4131 SVNHAKHAADIFSEKKYR---TKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNAT 4187 + AK A +FSE KY+ K + F D + + AK SGE+ +IKY++++ T Sbjct: 531 QLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKT 590 Query: 4188 KSKYTLT-ETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQS 4246 K K T ++ LLH+ Q A++ + YK+G+E K T + LP D V HA + S Sbjct: 591 KGKAMGTADSRLLHSLQ-IAKMSSEVEYKKGFEESK-TRFHLPMDMVNIRHAKKAQTLAS 648 Query: 4247 ELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMV 4306 +L Y+ K+ Y +P +D K W + A +Q+E YK D K + + Sbjct: 649 DLDYR----KKLHEYTVLP---EDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSL 701 Query: 4307 SVLAAKQGQTLVSDIDYRNYLHQ--WMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGI 4364 ++ AK+ LVS+ +YR + + + D + + A+K+ +LQS Y+A E Sbjct: 702 NLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQ 761 Query: 4365 GWIPLDSVDHVRVTKNQEMMSQIKYKKN-ALENYPNFRSVVDPPEIVLAKINSVNQSDVK 4423 I D ++ N +S+ YK + + F +D + AK S+VK Sbjct: 762 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 821 Query: 4424 YKETFNKAKGKYTFSPDT---PHISHSKDMGKLYSTILYKGAWEGTKAYGY-TLDERYIP 4479 YKE + +++GK + D +SHS M KL S + YK +E TK+ + +LD + Sbjct: 822 YKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLD--MVH 879 Query: 4480 IVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYED 4539 +V A+ A + +++ YK + H+ A Sbjct: 880 LVHARKAQHLATDVGYKTA----EHHFTA------------------------------- 904 Query: 4540 TKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTS-----LLEEPNVIRVRNAQEIL 4594 +P DM AK+ + SD +YR +W NV + + A E++ Sbjct: 905 ------LPTDMKVE-WAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLNVEQAKKAGELI 956 Query: 4595 SDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLY 4654 S+ Y+ + LK + DTP+++ A+ SY Y G+ +Y D P Sbjct: 957 SEKKYRQHPDALKFTS--IKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEV 1014 Query: 4655 VTAVQSGINASEVKYKENYHQIKD-KYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKA 4713 + A + +N SE +YKE++ +++D Y L+ + + + + S YKEA++++K Sbjct: 1015 LLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK- 1073 Query: 4714 TSYILPSSTL----SLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRV 4769 +L S +L SL H+ L S + Y++ +E KA + LP Sbjct: 1074 -GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPL-------------- 1118 Query: 4770 GKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVN 4829 DM +V AK +Q S DY+ L ++ + Sbjct: 1119 ------------------------DMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRL 1154 Query: 4830 DHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRND 4889 +K S+ +Y+ DLN+++G+ C + T EI K A +L + KY+ H + Sbjct: 1155 SCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK-- 1212 Query: 4890 YKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVA--PTTKTVDLDRALHAYKLQSS 4947 Y VTDTP + A S + ++ +Y G+ A T T+ L + A K ++ Sbjct: 1213 YTAVTDTPNLLHAKFSNQITNERLY------KAAGEDARHEYTMTLGLPEFIRA-KTNAA 1265 Query: 4948 NL----YKTSLRTL-PTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPK 5002 NL YK S R L GY+L + F+ + + ++S F Y+ ++ K G +GP+ Sbjct: 1266 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYR--HDFVKERGKLIGPQ 1323 Query: 5003 ----DVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKS 5058 D H RR+ + SE YR + + H D + K Q S+ Y++ Sbjct: 1324 SVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRT 1383 Query: 5059 DFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLR 5118 + K +LP ++ + + S+++YK DL +KG G +P M ++ Sbjct: 1384 QYHK----FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAG 1439 Query: 5119 KLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDT 5178 +L S Y K + K+ V+D+P+ + H +E +YR+ + +T +PD Sbjct: 1440 ELISETKYRKKPDSI--KFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDH 1497 Query: 5179 PDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTAL-----KHAKDVKDMVSEKKYK- 5232 PD RA +L + +L ++ AG+ L + A+ +++ S+ +YK Sbjct: 1498 PDFTRA----RLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKE 1553 Query: 5233 --IQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHR 5290 ++ ++ Y V D P + SD YK+ F K++ ++H+ D ++ + Sbjct: 1554 AFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAK 1613 Query: 5291 KVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG 5347 + S + Y++ L P++ H + SDVKYK DL +G+G Sbjct: 1614 RSQQLASDVHYRQ----PLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVG 1666 Score = 323 bits (829), Expect = 3e-87 Identities = 381/1576 (24%), Positives = 656/1576 (41%), Gaps = 122/1576 (7%) Query: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY-VWDTPQILHAKKSYDLQSQLQYTAA 4637 L +P ++R+ A++ L + Y +D +G G + TP AKK+ L SQ++Y Sbjct: 138 LPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196 Query: 4638 GKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYT-TVLETVDYDRTRNLK 4696 E + ++ V DTP + + S+V+Y E+Y Q + K + + T Y + Sbjct: 197 HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRAN 256 Query: 4697 NLYSSNLYKEAWD---RVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTL 4753 L S Y + + R A I L+ A Y EEYE+ + + Sbjct: 257 ELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQ-----GYPEEYEEHRGKGSF 311 Query: 4754 PRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHI----VPDMVEMVTAKDSQKKVS 4809 P + P + +L D YR + K K H D + + A+ K VS Sbjct: 312 PAMI--TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369 Query: 4810 EIDYRLRLHEWICHP----DLQVNDHVRKVTDQISDIVYKDDL-NWLKGIGCYVWDTPEI 4864 E++Y+ L H + +V K++ SD YK++ N ++G V Sbjct: 370 EVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRT 429 Query: 4865 LHAKHAYDLRDDIKYKAHM-------------------------LKTRN--------DYK 4891 LHA L ++ YKA LK N Y Sbjct: 430 LHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 489 Query: 4892 LVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYK 4951 VTDTP VQA + +QLS Y DY + P L +A KL S YK Sbjct: 490 SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLP-QDVPQLVKAKTNAKLFSEVKYK 548 Query: 4952 TSL-RTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPKDVPFVHVR 5010 +T G+ + D K + ++S KYKE YE TK G +G D +H Sbjct: 549 EGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK--GKAMGTADSRLLHSL 606 Query: 5011 RVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISL 5070 ++ ++SE Y++ + + K + H D IR KK Q S+L Y+ K+ + + L Sbjct: 607 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRK---KLHEYTV-L 662 Query: 5071 PYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKA 5130 P + + + S+++YK DL +KG G + ++ +++ +L S Y + Sbjct: 663 PEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRV 722 Query: 5131 RKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKL 5190 ++ K+ V D+ + ++ + S + Y+A ++ +T D P L+A+ Sbjct: 723 DEL--KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN 780 Query: 5191 QSQYLYVELATKERPH-HHAGNQTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDT- 5248 S+ LY ++ + AK +D+ SE KYK YE+ + K D Sbjct: 781 LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ 840 Query: 5249 --PILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYK--EN 5304 + + + S+L YK+ F+ TK + H D + +V+ RK + + YK E+ Sbjct: 841 GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH 900 Query: 5305 YMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKT 5364 + + ++P + + SD +Y+ D+ W+KG+G A + + A+K Sbjct: 901 HFT------ALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGE 954 Query: 5365 LYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEP 5424 L S+ KY++ + K F + D+P + + ++ YR E K Y D P Sbjct: 955 LISEKKYRQHPDALK--FTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLP 1012 Query: 5425 RHLLAKTAGDQISQIKYRKNYEKSKD-KFTSIVDTPEHLRTTKVNKQISDILYKLEYNKA 5483 LLAK IS+ +Y++++ K +D + +D + ISD YK + K Sbjct: 1013 EVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKM 1072 Query: 5484 KPR--GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKV 5541 K + G ++ D L H SD+ YK+ ++ +K+ + D + AK A + Sbjct: 1073 KGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTL 1132 Query: 5542 NTNLDYKKQYEANKAHWKWTPDRPDF-LQAAKSSLQ-QSDFEYKLDREFLKGCKLSVTDD 5599 +N DYK ++T D L AK + + QS+ Y+ D F++G + Sbjct: 1133 ASNQDYKHPLP------QYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGT 1186 Query: 5600 KNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKH 5659 + + + S+ KY++ + T AV DTP +L AK + + +E YK Sbjct: 1187 LEIEGRKKASELISESKYRQHPHSFKYT--AVTDTPNLLHAKFSNQITNERLYK--AAGE 1242 Query: 5660 LAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAK 5719 A+ YT + + K ++SD YK+ + + Y + +E + A Sbjct: 1243 DARHEYTMTLGLPEFIRAKTNAANLSDARYKESW-RNLRAQGYKLTIEALPFQAARASGD 1301 Query: 5720 KQSDVAYRKD-AKEN---LHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSML 5775 SD YR D KE + +V D P I+ + + SE++YR + + Sbjct: 1302 IASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPM 1361 Query: 5776 GRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKAD 5835 + AK A L+S YR + K P+D ++ K A+ L SE++YK+D Sbjct: 1362 DMVHLVHAKNAQALASDHDYRTQYHKFTAL-----PEDLKM-AWAKKAHALQSELRYKSD 1415 Query: 5836 LKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATE 5895 L + S M +L S +Y+KK + K + T+ D+ + +H K + Sbjct: 1416 LIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIK--FTTVVDSPDLVHAKNSYM 1473 Query: 5896 LQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEV 5955 + Y+ + + L + P + A+ + S K YR +E++ G L+ Sbjct: 1474 HCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDA 1533 Query: 5956 TPALLHVKYATKIASEKEYRKDLEESIRGKGL----TEMEDTPDMLRAKNATQILNEKEY 6011 P + + +IAS+ Y+ E +R +GL ++D P M N ++ ++ EY Sbjct: 1534 IP-FQTARASREIASDFRYK---EAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1589 Query: 6012 KRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIH 6071 K+D K R + + P ++A+ + +AS + Y+Q T + + H Sbjct: 1590 KKDF---AKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQP----TCDPEQLGLRH 1642 Query: 6072 AQQVKNLSSQKKYKED 6087 AQ+ L S KYK D Sbjct: 1643 AQKAHQLQSDVKYKSD 1658 Score = 322 bits (825), Expect = 8e-87 Identities = 379/1597 (23%), Positives = 669/1597 (41%), Gaps = 203/1597 (12%) Query: 4793 PDMVEMVTAKDSQKKVSEIDYRLRLHEW----ICHPDLQVNDHVRKVTDQISDIVYKDDL 4848 P++V MV A+ S + DY + + P Q +K S + YK Sbjct: 141 PEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQ---RAKKANQLASQVEYKRGH 197 Query: 4849 NWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKL-VTDTPVYVQAVKSGK 4907 + V DTPE+L +K L+ D++Y + R TP Y A ++ + Sbjct: 198 DERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANE 257 Query: 4908 QLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGD- 4966 SD YH Y +RG P + + ++ Y +R G Sbjct: 258 LASDVRYHQQYQKEMRGMAGPAIGAEGI------LTRECADQYGQGYPEEYEEHRGKGSF 311 Query: 4967 ----TPHFKHIKDTRYMSSYFKYKEAYEHTK--AYGYTLGPKD-VPFVHVRRVNNVTSER 5019 TP +++ K ++S KY++ + K A+ ++L +D + + VN + SE Sbjct: 312 PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371 Query: 5020 LYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFK-MQGHMISLPYTPQVIH 5078 Y++ + +TP+ R V K + S+ YK ++ M+G + + +H Sbjct: 372 EYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLH 431 Query: 5079 CRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRD--- 5135 VG + S++ YK D + D+V + L +Y K ++D Sbjct: 432 AMKVGSLASNVAYKADYK------------HDIVDYNYPATLTPSYQTAMKLVPLKDANY 479 Query: 5136 -------KYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQ 5188 KY V DTP+ + + LS + YRA +K K +T D P L++AK Sbjct: 480 RQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNA 539 Query: 5189 KLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPD 5247 KL S+ Y E K + +L AK ++ S KYK +YEK K K D Sbjct: 540 KLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTAD 599 Query: 5248 TPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMS 5307 + +L + A + S++ YK+ F+++K ++H D ++I + +K S + Y++ Sbjct: 600 SRLLHSLQIAKMS-SEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRK---- 654 Query: 5308 QLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYS 5367 +L + +P+ + + S+++YK DL W+KG+G + + A+K L S Sbjct: 655 KLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS 714 Query: 5368 KYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHL 5427 + Y++ + K F V DS H K + +L + Y+A EQ +Y + DEP L Sbjct: 715 EKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFL 772 Query: 5428 LAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPR 5486 A+ +S+ Y+ ++E K K F +D+ L S++ YK +Y +++ + Sbjct: 773 QARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGK 832 Query: 5487 --GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTN 5544 G + + H ++ S+L+YK+ ++ KS C + D VH+ A+ A + T+ Sbjct: 833 LIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATD 892 Query: 5545 LDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVL 5604 + YK + H+ P A K+ QSD +Y+ D +++KG T N Sbjct: 893 VGYKTA----EHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQ 948 Query: 5605 ALRNTLIESDLKYKE----------------------------KHVKERGTC---HAVP- 5632 A + + S+ KY++ + +E+G H P Sbjct: 949 AKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPT 1008 Query: 5633 -DTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKK 5691 D P++LLAK + +SE +YK+ K L G Y + K + +SD YK+ Sbjct: 1009 ADLPEVLLAKLNAMNISETRYKESWSK-LRDGGYKLRLDALPFQAAKASGEIISDYKYKE 1067 Query: 5692 KFVKEKGKSNYSIMLEPP-EVKHAMEVAKKQSDVAYRKD---AKENLH------------ 5735 F K KG+ S LE + H++ QSDV Y+K +K H Sbjct: 1068 AFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAK 1127 Query: 5736 -----------------YTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLGRP 5778 YT++A+ + A +A K SE YR+ + G Sbjct: 1128 KAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTL 1187 Query: 5779 DIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKA---D 5835 +IE KKA++L S+ KYR++ K P K +N + +E YKA D Sbjct: 1188 EIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHA----KFSNQITNERLYKAAGED 1243 Query: 5836 LKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYE--KSKGHYHTIPDNLEQLHLKEA 5893 + + + E + N + L+ + +YK+ + +++G+ TI + L + + Sbjct: 1244 ARHEYTMTLGLPE--FIRAKTNAANLSDA-RYKESWRNLRAQGYKLTI-EALPFQAARAS 1299 Query: 5894 TELQSIVKYKEKYEKERGK---PMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNL 5950 ++ S Y+ + KERGK P + P + Q+QS +YR+ S +L Sbjct: 1300 GDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHL 1359 Query: 5951 TGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKE 6010 V L+H K A +AS+ +YR + T + + M AK A + +E Sbjct: 1360 PMDMVH--LVHAKNAQALASDHDYRTQYHK------FTALPEDLKMAWAKKAHALQSELR 1411 Query: 6011 YKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEII 6070 YK DL + +G+ +A +P A+ A ++ S+ KY++ + K FT+VVD+P+++ Sbjct: 1412 YKSDL---IGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIK--FTTVVDSPDLV 1466 Query: 6071 HAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKG-- 6128 HA+ +++ Y+ +S+ Y + D P+ R R N + S Y+ + ++ Sbjct: 1467 HAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGS 1526 Query: 6129 --------KITVVQDTPEI---LRVKE-------------------NQKNFSSV------ 6152 + + EI R KE K+F +V Sbjct: 1527 YDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSD 1586 Query: 6153 -LYKEDVSPGTAIGKT----PEMMRVKQTQDHISSVKYKEAIGQGTPIPDLPEVKRVKET 6207 YK+D + + + P +++ K++Q S V Y++ + Q T P+ ++ ++ Sbjct: 1587 NEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKA 1646 Query: 6208 QKHISSVMYKENL----GTGIPTTVTPEIERVKRNQE 6240 + S V YK +L G G + ++E +R E Sbjct: 1647 HQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAE 1683 Score = 307 bits (787), Expect = 2e-82 Identities = 385/1633 (23%), Positives = 673/1633 (41%), Gaps = 246/1633 (15%) Query: 5109 PDMVRSRHLRKLWSNYLYTDKARKMRDKYKV-VLDTPEYRKVQELKTHLSELVYRAAGKK 5167 P++VR RK YT+ + R K + TP Y++ ++ S++ Y+ + Sbjct: 141 PEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199 Query: 5168 QKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQTTALKHAKDVKDMV 5226 + S F++V DTP+LLR+K G +LQS Y E ++R T A + AK ++ Sbjct: 200 RISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELA 259 Query: 5227 SEKKYKIQYEK-------------------MKDKYT----------------PVPDTPIL 5251 S+ +Y QY+K D+Y P TP Sbjct: 260 SDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAY 319 Query: 5252 IRAKRAYWNASDLRYKETFQKTKGK--YHTV--KDALDIVYHRKVTDDISKIKYKENYMS 5307 AK+A+ ASD++Y++ F K KG YH++ +D L + + V +S+++YK++ S Sbjct: 320 QNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLES 379 Query: 5308 QLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLT-----WLKGIGC-------------- 5348 G + + P+ + ++ SD KYKE+ +G+G Sbjct: 380 SRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLA 439 Query: 5349 --------YAYDTPDF----TLAEKNKTLYSKYKYKEVFERTKSD---FKYVADSPINRH 5393 Y +D D+ TL +T K+ R D + V D+P Sbjct: 440 SNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQ 499 Query: 5394 FKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK-F 5452 K Q ++ YRADYE+ K Y L D P+ + AKT S++KY++ +EK+K K F Sbjct: 500 AKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGF 559 Query: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKY 5512 +D L + S+I YK EY K K + T LLH ++ S+++Y Sbjct: 560 EMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSR--LLHSLQIAKMSSEVEY 617 Query: 5513 KEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAK 5572 K+ ++ +K+ + D V+I+ AK A + ++LDY+K+ + P+ A K Sbjct: 618 KKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLH----EYTVLPEDMKTQWAKK 673 Query: 5573 SSLQQSDFEYKLDREFLKGCK---------------------------------LSVTDD 5599 + QS+ +YK D ++KG SVTD Sbjct: 674 AYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDS 733 Query: 5600 KNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKH 5659 A ++ ++S + YK + + D P L A+ + +SE YK + Sbjct: 734 SQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQ 793 Query: 5660 LAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLE-PPEVKHAMEVA 5718 A+G L ++ + K S+ YK+ + + +GK + ++ ++ H+++++ Sbjct: 794 KAKGFELRL-DSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMS 852 Query: 5719 KKQSDVAYRK---DAKENLH-----------------------------YTTVADRPDIK 5746 K QS++ Y+K D K H +T + ++ Sbjct: 853 KLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVE 912 Query: 5747 KATQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKT 5806 A +A S+ +YRA + G G ++E AKKA +L S+ KYR++ D K + Sbjct: 913 WAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTS 972 Query: 5807 PKYNPKDSQLYKVMKDANNLASEVKYKA---DLKKLHKPVTDMKESLIMNHVLNTSQLAS 5863 K P+ Q + + A + Y+ ++K + P D+ E L+ LN ++ Sbjct: 973 IKDTPEMVQA----RISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAK--LNAMNISE 1026 Query: 5864 SYQYKKKYEKSK-GHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTY 5922 + +YK+ + K + G Y D L K + E+ S KYKE +EK +G+ + Sbjct: 1027 T-RYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1085 Query: 5923 ITAKES---QQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLE 5979 I+ S +QS Y+K +E S K + L++ AL+H K A +AS ++Y+ L Sbjct: 1086 ISLAHSVYATSLQSDVNYKKGFEHS-KAQFHLPLDMA-ALVHAKKAQTLASNQDYKHPLP 1143 Query: 5980 ESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARN 6039 + T + + + AK A ++ +E Y+ DL RG+ + T + + Sbjct: 1144 Q------YTSLAEDLRLSCAKKAHKLQSENLYRSDLNFM---RGVACVIPGTLEIEGRKK 1194 Query: 6040 ATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVL 6099 A+++ S+ KY+Q K +T+V DTP ++HA+ +++++ YK E + Y L Sbjct: 1195 ASELISESKYRQHPHSFK--YTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTL 1252 Query: 6100 DTPEIQRVRENQKNFSLLQYQCDLKNSKG---KITVVQDTPEILRVKENQKNFSSVLYKE 6156 PE R + N N S +Y+ +N + K+T+ + + + S LY+ Sbjct: 1253 GLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTI--EALPFQAARASGDIASDFLYRH 1310 Query: 6157 DV--SPGTAIGKTPEMMRVKQTQDHISSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSV 6214 D G IG P+ +R D P ++ + + S + Sbjct: 1311 DFVKERGKLIG--PQSVR------------------------DDPRIQHCRRMGQLQSEL 1344 Query: 6215 MYKENLGTGIPTTVTP----EIERVKRNQENFSSVLYKENLGKGIPTPITPEMERVKRNQ 6270 Y+ + P + K Q S Y+ K P +M K+ Sbjct: 1345 QYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAH 1404 Query: 6271 ENFSSVLYKENM----GKGTPLAVTPEMERVKHNQENISSVLYKENVGKATATPV--TPE 6324 S + YK ++ G G +P+ME K E IS Y++ T V +P+ Sbjct: 1405 ALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPD 1464 Query: 6325 MQRVKRNQENISSVLYK----ENLGKATPTPFTPEMERVKRNQENFSSVLYKENMRKATP 6380 + K + + + +Y+ E+L + T P P+ R + N + S +Y+ + + Sbjct: 1465 LVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRA 1524 Query: 6381 TPVTPEMER-----AKRNQENISSVLYSDSFRKQIQGKAAY--VLDTPEMRRVRETQRHI 6433 ++ A+ ++E S Y ++F + + Y V D P M+ R Sbjct: 1525 GSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQ 1584 Query: 6434 STVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYRGIQRKVVEMEQKRNDQDQE 6493 S +Y +DF K + F P + K++ Q SD++YR + Q D +Q Sbjct: 1585 SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYR------QPLPQPTCDPEQ- 1637 Query: 6494 TITGLRVWRTNPGSVFDYDPAEDNIQSRSL-----HMINVQAQRRSREQSRSASALSISG 6548 GLR + D D +R + V+ RR+ E + +A L + G Sbjct: 1638 --LGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELA-NARGLGLQG 1694 Query: 6549 GEEKSEHSEAPDH 6561 +E EA DH Sbjct: 1695 AYRGAEAVEAGDH 1707 Score = 282 bits (721), Expect = 9e-75 Identities = 349/1533 (22%), Positives = 614/1533 (40%), Gaps = 199/1533 (12%) Query: 5038 TPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQV 5097 TP ++ KK + S++ YK + ++ TP+++ + + SD++Y ED + Sbjct: 175 TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ 234 Query: 5098 LKGFGCF-LYDTPDMVRSRHLRKLWSNYLYTDKARK-MRDKYKVVLDTPEYRKVQELKTH 5155 +G G F TP ++ +L S+ Y + +K MR + + + Sbjct: 235 QRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294 Query: 5156 LSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKER--PHHHA--GN 5211 + K F ++ TP AK+ +L S Y + K + H+H+ Sbjct: 295 GQGYPEEYEEHRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353 Query: 5212 QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQ 5271 LK A+ V +VSE +YK E + +TP + SD +YKE +Q Sbjct: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQ 413 Query: 5272 K-TKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDT 5330 +G+Y V ++ KV S + YK +Y + + + Sbjct: 414 NHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVP 473 Query: 5331 VSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPI 5390 + D Y++ + LK DTP A+ N S Y+ +E+ K ++ D P Sbjct: 474 LKDANYRQSIDKLKYSS--VTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQ 531 Query: 5391 NRHFKYATQLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSK 5449 K +L +E KY+ +E+ K K + + +D L AK +G+ S IKY++ YEK+K Sbjct: 532 LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591 Query: 5450 DKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSD 5509 K D+ L + ++ K S++ YK + ++K R + + D + H +K + SD Sbjct: 592 GKAMGTADS-RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPM-DMVNIRHAKKAQTLASD 649 Query: 5510 LKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQ 5569 L Y+ + T+ P+ + + AK AY + + L YK K T + Q Sbjct: 650 LDYR----KKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQ 705 Query: 5570 AAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCH 5629 A K+ S+ Y+ + LK SVTD A ++ ++S + YK + + Sbjct: 706 AKKAGQLVSEKNYRQRVDELKFT--SVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYT 763 Query: 5630 AVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNY 5689 D P L A+ + +SE YK + A+G L ++ + K S+ Y Sbjct: 764 ISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRL-DSLTFLAAKAKRDLASEVKY 822 Query: 5690 KKKFVKEKGKSNYSIMLE-PPEVKHAMEVAKKQSDVAYRK---DAKENLH---------- 5735 K+ + + +GK + ++ ++ H+++++K QS++ Y+K D K H Sbjct: 823 KEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVH 882 Query: 5736 -------------------YTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLG 5776 +T + ++ A +A S+ +YRA + G G Sbjct: 883 ARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATG 942 Query: 5777 RPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQ-----------LYKVMKD--- 5822 ++E AKKA +L S+ KYR++ D K + K P+ Q LY+ + Sbjct: 943 SLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIK 1002 Query: 5823 ------------------ANNLASEVKYKADLKKLHKPVTDMK-ESLIMNHVLNTSQLAS 5863 A N+ SE +YK KL ++ ++L + ++ S Sbjct: 1003 HHYTPTADLPEVLLAKLNAMNI-SETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1061 Query: 5864 SYQYKKKYEKSKGHY---HTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETP 5920 Y+YK+ +EK KG ++ D++ H AT LQS V YK+ +E + + L + Sbjct: 1062 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMA 1121 Query: 5921 TYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEE 5980 + AK++Q + S ++Y+ + T L L K A K+ SE YR DL Sbjct: 1122 ALVHAKKAQTLASNQDYKHPLPQ------YTSLAEDLRLSCAKKAHKLQSENLYRSDLN- 1174 Query: 5981 SIRG-----KGLTEME---------------------------DTPDMLRAKNATQILNE 6008 +RG G E+E DTP++L AK + QI NE Sbjct: 1175 FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNE 1234 Query: 6009 KEYKR-----------------------------DLELEVKGRGLNA----MANETPDFM 6035 + YK D + R L A + E F Sbjct: 1235 RLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQ 1294 Query: 6036 RARNATDIASQIKYKQSAEMEKANFT---SVVDTPEIIHAQQVKNLSSQKKYKEDAEKSM 6092 AR + DIAS Y+ E+ SV D P I H +++ L S+ +Y+ A S Sbjct: 1295 AARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQ 1354 Query: 6093 SYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSV 6152 + + +D + KN L D + K T + + ++ K+ S + Sbjct: 1355 AQFHLPMDMVHLVHA----KNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSEL 1410 Query: 6153 LYKEDVSPGTAIG----KTPEMMRVKQTQDHISSVKYKEAIG--QGTPIPDLPEVKRVKE 6206 YK D+ IG ++P+M K+ + IS KY++ + T + D P++ K Sbjct: 1411 RYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKN 1470 Query: 6207 TQKHISSVMYK----ENLGTGIPTTVTPEIERVKRNQENFSSVLYKENLGKGIPTPITPE 6262 + H + MY+ E+L P+ R + N + S +Y+ + + Sbjct: 1471 SYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFR 1530 Query: 6263 MERV-----KRNQENFSSVLYKENMGKGTPLAV-------TPEMERVKHNQENISSVLYK 6310 ++ + + ++E S YKE + L + P M+ + S YK Sbjct: 1531 LDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYK 1590 Query: 6311 ENVGKATA----TPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVKRNQENF 6366 ++ K+ + + P + + KR+Q+ S V Y++ L + T P + ++ + Sbjct: 1591 KDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQ 1650 Query: 6367 SSVLYKENMRKATPTPVTP----EMERAKRNQE 6395 S V YK ++ TP ++E A+R E Sbjct: 1651 SDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAE 1683 Score = 82.8 bits (203), Expect = 1e-14 Identities = 114/487 (23%), Positives = 199/487 (40%), Gaps = 51/487 (10%) Query: 6031 TPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEK 6090 TP + R + S I ++ E K+ F + + + A + L++++ Y + Sbjct: 70 TPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANERAYWTGYGE 129 Query: 6091 SMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITV-VQDTPEILRVKENQKNF 6149 ++ L PEI R+ E +K+ +Y D + +GK + TP R K+ + Sbjct: 130 GNAWCPGALPDPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLA 188 Query: 6150 SSVLYK----EDVSPGTAIGKTPEMMRVKQTQDHISSVKYKEAI----GQGT-PIPDLPE 6200 S V YK E +S + + TPE++R K S V+Y E G+G+ P P Sbjct: 189 SQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248 Query: 6201 VKRVKETQKHISSVMY-----KENLGTGIPTTVTPEI---ERVKRNQENFSSVLYKENLG 6252 + K + S V Y KE G P I E + + + Y+E+ G Sbjct: 249 YQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEE-YEEHRG 307 Query: 6253 KG-IPTPITPEMERVKRNQENFSSVLYKENMGK--------GTPLAVTPEMERVKHNQEN 6303 KG P ITP + K+ E S + Y+++ K P +++ + + Sbjct: 308 KGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKL 367 Query: 6304 ISSVLYKENVGKATATPV----TPEMQRVKRNQENISSVLYKENL-----GKATPTPFTP 6354 +S V YK+++ + + TP+ + V + + S YKEN G+ Sbjct: 368 VSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDR 427 Query: 6355 EMERVKRNQENFSSVLYKENMRKAT-----PTPVTPEMERAKRNQENISSVLYSDSFRKQ 6409 + S+V YK + + P +TP + A + V D+ +Q Sbjct: 428 RTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMK------LVPLKDANYRQ 481 Query: 6410 IQGKAAY--VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQD 6467 K Y V DTP++ + + + +S V Y D+EK+K +T P + K N + Sbjct: 482 SIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKL 541 Query: 6468 FSDINYR 6474 FS++ Y+ Sbjct: 542 FSEVKYK 548 >gi|46049092 nebulin-related anchoring protein isoform C [Homo sapiens] Length = 1695 Score = 1176 bits (3042), Expect = 0.0 Identities = 615/1520 (40%), Positives = 969/1520 (63%), Gaps = 38/1520 (2%) Query: 456 KNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHT-YKVHPDK--TKFTQVTDSPVLL 512 + Y +YE+ RGKG FP IT Y+ KK +Q YK D+ ++F+ V D+P LL Sbjct: 155 EEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELL 214 Query: 513 QAQVNSKQLSDLNYKAKHESEKFKCHIPPD-TPAFIQHKVNAYNLSDNLYKQDWEKSKAK 571 +++ ++ SD+ Y +E ++ K P TPA+ K SD Y Q ++K Sbjct: 215 RSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQK---- 270 Query: 572 KFDIKVDAIPLLAAKAN-TKNTSDVM---YKKDYEKNKGKMIGVLSINDDPKMLHSLKVA 627 +++ A P + A+ T+ +D Y ++YE+++GK G P ++ K Sbjct: 271 --EMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGK--GSFPAMITPAYQNAKKAH 326 Query: 628 KNQSDRLYKENYEKTKAKSMNYCETPKY------QLDTQLKNFSEARYKDLYVKDVLGHY 681 + SD Y++++ K K + +Y P Q + K SE +YK+ Y + G Y Sbjct: 327 ELASDIKYRQDFNKMKGAA-HYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRY 385 Query: 682 VGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKLDQCKDHTYK 741 G D H MKV + S+ +YKA+Y+ D +P T+T Y+ KL KD Y+ Sbjct: 386 EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR 445 Query: 742 VHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVNAY 801 DK K+++VTD+P ++QA++N +QLS +NY+A +E K +P D PQ ++ + NA Sbjct: 446 QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK 505 Query: 802 NLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSI 861 S+ YK+ WEK+K K F++K+DA+ LLAAKA+ + S++ YK++YEK+KGK +G Sbjct: 506 LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA-- 563 Query: 862 NDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHIL 921 D ++LHSL+ AK S+ EY+K +E+SKT + P+DM+ + AKK+Q +ASD+DY+ L Sbjct: 564 --DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKL 621 Query: 922 HSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASDILNE 981 H Y+ P+ + AKKAY LQS+++YKAD +WMKG GW+ GSL +E+AK+A +++E Sbjct: 622 HEYTVLPEDMKTQWAKKAYGLQSELQYKADL-AWMKGVGWLTEGSLNLEQAKKAGQLVSE 680 Query: 982 KKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAK 1041 K YRQ D LKFTS+ D+ +K +Q +S +AYKA E+ +H+Y + D P F+QA+ Sbjct: 681 KNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQAR 740 Query: 1042 VNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVG 1101 NA N+SE +YK+ ++ KG++LR D++ AAKA R AS+V+YK+DYE+++GK++G Sbjct: 741 ANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIG 800 Query: 1102 FQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVSNVNY 1161 + +Q D ++ H + ++K+QS+ EYKK +E TKS+ + DM ++V A+KAQ + ++V Y Sbjct: 801 AKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGY 860 Query: 1162 KHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGD 1221 K + HH+T LP M +E +K +QSDN Y+ D WMKG+GW+ GSL+VE+ KKAG+ Sbjct: 861 KTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVK-WMKGMGWVATGSLNVEQAKKAGE 919 Query: 1222 ALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQF 1281 ++EKKYRQHPD LKFTSI D+P MVQA+ + Q D LY+ +GE++KH YT + DLP+ Sbjct: 920 LISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEV 979 Query: 1282 LQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKG 1341 L AK NA NIS+ YK W L G + DA+P AAKAS I SDYKYKEA+EK KG Sbjct: 980 LLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKG 1039 Query: 1342 KHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVAT 1401 + +G RSL+DD L H + LQSD YKK +E++K +H P DM ++ AK AQ +A+ Sbjct: 1040 QMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLAS 1099 Query: 1402 NVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVK 1461 N +YK PL YT L + + L + +++QS+N+Y+ + N F++G+ + G+LE+E K Sbjct: 1100 NQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN-FMRGVACVIPGTLEIEGRK 1158 Query: 1462 KAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPE 1521 KA + ++E KYRQHP + K+T+V D+ ++ A+ + + ++ YK GE +H+YT+ Sbjct: 1159 KASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLG 1218 Query: 1522 LPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYE 1581 LP+FI+AK NA N+SDA YK W+ A+GY L +A+P AA++S +IASD Y+ + Sbjct: 1219 LPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFV 1278 Query: 1582 KAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQ 1641 K +GK +G S++DDP++ H + ++QS+ +Y++G +S+ ++H P+DMV + AK +Q Sbjct: 1279 KERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQ 1338 Query: 1642 EVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEV 1701 +A++ +YR YH +T LP+ L + ++ A +QS+ YKSD MKGIGW+ + S ++ Sbjct: 1339 ALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIGWLALRSPQM 1397 Query: 1702 EKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIH 1761 E AKKAGE++SE KYR+ P+ +KFT +D+ + K++ ++ ++R+Y + D ++H Sbjct: 1398 ESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLH 1454 Query: 1762 ---VMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDY 1818 ++PD PD +R+N + +SDK+Y+ WE+ + YD R DAI + ARASR+IASD+ Sbjct: 1455 RYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDF 1514 Query: 1819 KYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSV 1878 +YK+A+ + +G IG+RS++DDP++ HF+ V ++QSD EYKK + KS++ FH+ D + Sbjct: 1515 RYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGL 1574 Query: 1879 VAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWL 1938 + AK+SQ++A++ +YR + P+ + A+ Q+QSD +YK+D + +G+GW Sbjct: 1575 LQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSD-LNLTRGVGWT 1633 Query: 1939 PLGSLEAEKNKKAMEIISEK 1958 P GS + E ++A E+ + + Sbjct: 1634 PPGSYKVEMARRAAELANAR 1653 Score = 1087 bits (2812), Expect = 0.0 Identities = 607/1646 (36%), Positives = 961/1646 (58%), Gaps = 92/1646 (5%) Query: 109 KGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVS 168 K + S TP ++ + +S + + DG+ K++ H D K+KD E A + Sbjct: 60 KNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLAN 119 Query: 169 KVLYKQNWEDTKDKYLLPPDA---PELVQAVKNTAMFSKKLYTEDWEADKSL-FYPYNDS 224 + Y W + P A PE+V+ V+ ++ YTED+E + +P + Sbjct: 120 ERAY---WTGYGEGNAWCPGALPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMIT 175 Query: 225 PELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENK 284 P +R +A + S V YK+G E+ ++F+ + D P++ +K S +Y EDYE + Sbjct: 176 PAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQ 235 Query: 285 IKGKWSE----TPCFEVANAR------------------------MNADNISTRK----- 311 +GK S TP +++A + A+ I TR+ Sbjct: 236 -RGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294 Query: 312 ---YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASE 368 Y E++E + + F TP Y+ KKA AS +KY++D+ K KG A Y+ LPA + Sbjct: 295 GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQD 354 Query: 369 NPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLK 428 N L+Q A+S+N S+ KYK++Y Sbjct: 355 NLVLKQ---------------------AQSVN--------------KLVSENKYKENYQN 379 Query: 429 DILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQC 488 + G Y G D H MKV + S+ YKA+Y+ D +P T+T Y+ KL Sbjct: 380 HMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPL 439 Query: 489 KDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQ 548 KD Y+ DK K++ VTD+P ++QA++N++QLS +NY+A +E K +P D P ++ Sbjct: 440 KDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVK 499 Query: 549 HKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKM 608 K NA S+ YK+ WEK+K K F++K+DA+ LLAAKA+ + S++ YK++YEK KGK Sbjct: 500 AKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA 559 Query: 609 IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEAR 668 +G D ++LHSL++AK S+ YK+ +E++K + P ++ + ++ Sbjct: 560 MGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR----FHLPMDMVNIRHAKKAQTL 611 Query: 669 YKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEA 728 DL + L Y ED K S+ YKA+ KG + + +A Sbjct: 612 ASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQA 671 Query: 729 IKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPA 788 K + Y+ D+ KFT+VTDS + A+ + + S + YKA +E + I Sbjct: 672 KKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISK 731 Query: 789 DAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDY 848 D P F+Q R NA NLS+ +YK WE KAK F++++D++ LAAKA S+V YK+DY Sbjct: 732 DEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDY 791 Query: 849 EKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKS 908 E+S+GK+IGA + D +M HSL+ +K QS+ EY+K +E +K+ LDM+ + A+K+ Sbjct: 792 ERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKA 851 Query: 909 QAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLE 968 Q +A+DV YK H ++ P + V+ AKKAY LQSD +Y+AD WMKG GWV GSL Sbjct: 852 QHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLN 910 Query: 969 MEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKY 1028 +E+AK+A ++++EKKYRQHPD LKFTSI+D P VQ++I+ Q D Y+ +GE I H Y Sbjct: 911 VEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHY 970 Query: 1029 NLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQY 1088 DLP+ + AK+NA NISE YK L GY LR DA+P +AAKA+ + SD +Y Sbjct: 971 TPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKY 1030 Query: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA 1148 K+ +EK KG+M+G +SL+DD L H + +QSD YKK +E +K++++ P DM +V Sbjct: 1031 KEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVH 1090 Query: 1149 AKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPI 1208 AKKAQ + SN +YKH L YT L + + L +K ++QS+N+Y+ D N+M+G+ + Sbjct: 1091 AKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL-NFMRGVACVIP 1149 Query: 1209 GSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDV 1268 G+L++E KKA + ++E KYRQHP + K+T++ D+P ++ AK + + ++ LYKA GED Sbjct: 1150 GTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDA 1209 Query: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328 +H+YTM+ LP+F++AK NA N+SD YK W +L A+G + +A+P AA+AS +IAS Sbjct: 1210 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1269 Query: 1329 DYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV 1388 D+ Y+ + K +GK +G +S++DDP++ H + +LQS+ +Y++ +++ +H P DMV Sbjct: 1270 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMV 1329 Query: 1389 SITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIG 1448 + AK AQ +A++ +Y+ H +T LP+ + + + + +QS+ YK + +KGIG Sbjct: 1330 HLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIG 1388 Query: 1449 WIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVE 1508 W+ + S ++E KKAG+ ++E KYR+ PD++KFT+V DS +V A+++ ++ Y+ Sbjct: 1389 WLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSG 1448 Query: 1509 GEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSR 1568 + H+YT+ P+ P F +A++NAL++SD Y+ W++T A YD R DAIP A++SR Sbjct: 1449 DAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASR 1508 Query: 1569 NIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTP 1628 IASD +YKEA+ + +G Q+G+ S+ DDP++ H++NV ++QSD EYKK + S++++H+ Sbjct: 1509 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1568 Query: 1629 LDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWM 1688 D + AK+SQ++A++ +YRQ T P+ L + H++ A Q+QSD YKSD N Sbjct: 1569 TDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDL-NLT 1627 Query: 1689 KGIGWVPIESLEVEKAKKAGEILSEK 1714 +G+GW P S +VE A++A E+ + + Sbjct: 1628 RGVGWTPPGSYKVEMARRAAELANAR 1653 Score = 1035 bits (2675), Expect = 0.0 Identities = 578/1564 (36%), Positives = 916/1564 (58%), Gaps = 76/1564 (4%) Query: 1176 DLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVK--KAGDALNEK---KYRQ 1230 D E + N + ++ Y Y +G W P D E V+ +A +L E+ Y Q Sbjct: 107 DKEGAPNRQPLANERAYWTGYG---EGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQ 163 Query: 1231 HPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYN 1290 F +++ +P +AK+ + S + YK ++ +++ D P+ L++K A Sbjct: 164 PRGKGSFPAMI-TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQL 222 Query: 1291 ISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSK----GKHVGF 1346 SDV Y D+ KG+ AK + +ASD +Y + Y+K G +G Sbjct: 223 QSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGA 282 Query: 1347 RSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV-SITAAKMAQDVATNVNY 1405 + Y + Y + YE + P + + AK A ++A+++ Y Sbjct: 283 EGILTRECADQY--------GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKY 334 Query: 1406 KQPLH------HYTYLP--DAMSLEHTRNVNQIQSDNVYKDEYNSFLKG----------- 1446 +Q + HY LP D + L+ ++VN++ S+N YK+ Y + ++G Sbjct: 335 RQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRT 394 Query: 1447 IGWIPIGSLEVEKVKKAGDA------------------------LNERKYRQHPDTVKFT 1482 + + +GSL KA L + YRQ D +K++ Sbjct: 395 LHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 454 Query: 1483 SVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKA 1542 SV D+ +V A+ N +QLS +NY+ + EK K YT+ ++PQ ++AK NA S+ YK Sbjct: 455 SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 514 Query: 1543 DWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHY 1602 W+KT KG++++ DA+ ++AAK+S +AS+ KYKE YEK KGK +G D +L+H Sbjct: 515 GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 570 Query: 1603 MNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDA 1662 + +AK+ S+ EYKKG+E SKT++H P+DMV++ AKK+Q +A++ +YR+ H YT+LP+ Sbjct: 571 LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 630 Query: 1663 LNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEK 1722 + + ++ A +QS+ YK+D WMKG+GW+ SL +E+AKKAG+++SEK YRQ ++ Sbjct: 631 MKTQWAKKAYGLQSELQYKADLA-WMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDE 689 Query: 1723 LKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDK 1782 LKFT D+ + K ++ Y + + D P L +R N +S+K Sbjct: 690 LKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEK 749 Query: 1783 LYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPK 1842 LYK+ WE +K KG++LR D++ AA+A RD+AS+ KYK+ YE+++GK IG + ++ D + Sbjct: 750 LYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQ 809 Query: 1843 LVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNM 1902 + H +Q++K+QS+ EYKKG+E +K+ H +DM+ +V A+K+Q +AT+ Y+ H + Sbjct: 810 MSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTA 869 Query: 1903 LPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQ 1962 LP M E AK +QSDNQY+AD +MKG+GW+ GSL E+ KKA E+ISEKKYRQ Sbjct: 870 LPTDMKVEWAKKAYGLQSDNQYRAD-VKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQ 928 Query: 1963 HPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP--DIPQIILAKANA 2020 HPD LK++++ D+ MV A+ + + LY++ + + K H P D+P+++LAK NA Sbjct: 929 HPDALKFTSIKDTPEMVQARISYTQAVDRLYRE--QGENIKHHYTPTADLPEVLLAKLNA 986 Query: 2021 INMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRS 2080 +N+S+ YK S + + GY LR DA+P +AAKAS +I SDYKYK +EK KG+M+G RS Sbjct: 987 MNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRS 1046 Query: 2081 LEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHL 2140 LEDD L HS+ +QSD YKK +E++K +H P DM ++ AK AQ +N +YKH Sbjct: 1047 LEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHP 1106 Query: 2141 IHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYAS 2200 + +Y L + + + + +++QS+N Y+ D N + +G+ G+LE+E KKA+E S Sbjct: 1107 LPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN-FMRGVACVIPGTLEIEGRKKASELIS 1165 Query: 2201 DQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQA 2260 + KYRQHP +F++ +TD+ +++ AK + N+ LY + + + P+ ++A Sbjct: 1166 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA 1225 Query: 2261 KQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHV 2320 K N S YK W +GY L ++A+ Q A+AS DIASD+ Y+ + K+ G + Sbjct: 1226 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI 1285 Query: 2321 GFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVD 2380 G +S++DDP++ + ++QSE +Y++ + +F P+DM+ +V AK Q L SD D Sbjct: 1286 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD 1345 Query: 2381 YKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASE 2440 Y+ H++T LP+ + AKK + LQSE YKSDL ++GIGW L S + E K+A E Sbjct: 1346 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1405 Query: 2441 IISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDI 2500 +ISE KYR+ PD KFT++ D+ D+V AK + + ++R+YR + + ++PD PD Sbjct: 1406 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1465 Query: 2501 VLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLG 2560 A+ N ++ SDK+YR +E+ + YD +DAIP + A+ASREIAS+++YKE F + G Sbjct: 1466 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1525 Query: 2561 HHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVS 2620 IG R+++DDP+M ++V ++QSD EYKKDF K +++F S D G++ AK+ Q L S Sbjct: 1526 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1585 Query: 2621 DVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKR 2680 DV Y+ L Q TC P+Q + HA++A+ LQSD YKSDL +G+GW GS + E +R Sbjct: 1586 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR 1645 Query: 2681 ATQI 2684 A ++ Sbjct: 1646 AAEL 1649 Score = 1021 bits (2641), Expect = 0.0 Identities = 601/1615 (37%), Positives = 942/1615 (58%), Gaps = 85/1615 (5%) Query: 2108 NTKTS-YHTPADMLSVTAAKDAQANITNTN----YKHLIHKYILLPDAMNIELTRNMNRI 2162 NT TS YHTP + L+V +A + I + K + H + D E N + Sbjct: 62 NTFTSVYHTPLN-LNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDK---EGAPNRQPL 117 Query: 2163 QSDNEYKQDYNEWYKGLGWSPAGSLEVE-----KAKKATEYASDQKYRQHPSNFQFKKLT 2217 ++ Y Y E G W P + E +A+K+ + Y Q F + Sbjct: 118 ANERAYWTGYGE---GNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAM- 173 Query: 2218 DSMDMVLAKQNAHTMNKHLYTIDWNKDK----TKIHVMPDTPDILQAKQNQTLYSQKLYK 2273 + A Q A N+ +++ + ++ + DTP++L++K L S Y Sbjct: 174 ----ITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYT 229 Query: 2274 LGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVL 2333 +E+ KG + + Q+AK + ++ASD +Y Q Y+K++ G + +L Sbjct: 230 EDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMR---GMAGPAIGAEGIL 286 Query: 2334 SMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQELVSDVDYKNYLHQ----- 2387 + A Q + Y +++E+ + K S P + AKK EL SD+ Y+ ++ Sbjct: 287 TRECAD-QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAA 345 Query: 2388 -WTCLPDQNDVV--QAKKVYELQSENLYKSDLE-----WLRGIGWS-------PLGSLEA 2432 + LP Q+++V QA+ V +L SEN YK + + G+G +GSL + Sbjct: 346 HYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLAS 405 Query: 2433 EKNKRAS---EIIS---------------------EKKYRQPPDRNKFTSIPDAMDIVLA 2468 +A +I+ + YRQ D+ K++S+ D IV A Sbjct: 406 NVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQA 465 Query: 2469 KTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYD 2528 K NA+ S YR ++K+K + D P +V AK N S+ Y+ G+E+ K KG++ Sbjct: 466 KINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFE 525 Query: 2529 LPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDRE 2588 + +DA+ + AAKAS E+AS KYKE + K G +G D +++ S+ +AK+ S+ E Sbjct: 526 MKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVE 581 Query: 2589 YKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYD 2648 YKK FE+ KT+F P+DM+ + AKK QTL SD+DY+ LH++T LP+ A++AY Sbjct: 582 YKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYG 641 Query: 2649 LQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPM 2708 LQS+ YK+DL W+KG+GW+T GSL E+ K+A Q++S+ YRQ D+ KF+S+ DS M Sbjct: 642 LQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQM 701 Query: 2709 VLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRK 2768 AK + + Y ++ I D P L A+ N N SEKLYK E K K Sbjct: 702 EHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAK 761 Query: 2769 GYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQS 2828 G+++R+D++ AAKA RD+ASE KYKE Y + G IGA+ ++ D +M S+ ++K+QS Sbjct: 762 GFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQS 821 Query: 2829 DREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQ 2888 + EYKK FE K++ +DM+ +V A+K Q L +DV YK H +T LP V A++ Sbjct: 822 ELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKK 881 Query: 2889 AYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDS 2948 AY LQSDN Y++D++WM+G+GWV+ GSL+VE+ K+A E++S+K YRQ PD KFTS+ D+ Sbjct: 882 AYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDT 941 Query: 2949 LEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEA 3008 E V A+ + RLY E + K D PE++LA+ N +N SET YK + + Sbjct: 942 PEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKL 1001 Query: 3009 KKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAK 3068 + GY LR DA+P AAKAS ++ISDYKYK+ + K G +G+R++EDD + S++ Sbjct: 1002 RDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATS 1061 Query: 3069 IQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIH 3128 +QSD YKK FE K +F P+DM +V AKK QTL S+ DYK+ L ++T L + + Sbjct: 1062 LQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSC 1121 Query: 3129 ARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSV 3188 A++A+ LQS+N+Y+SDL ++RG+ V G++++ K+A+E++S++ YRQ P K+T+V Sbjct: 1122 AKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAV 1181 Query: 3189 TDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAM 3248 TD+ + AK + N+RLY A + + + + PE + A+ N N S++ Y+++ Sbjct: 1182 TDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESW 1241 Query: 3249 EEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLH 3308 + +GY L +A+P AA+AS DIASD+ Y+ + K+ G IG ++V DDP+I Sbjct: 1242 RNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRR 1301 Query: 3309 IAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQND 3368 + ++QS+ +Y++ + ++ P+DM+ +V AK Q L SD DY+ H++ LP+ Sbjct: 1302 MGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLK 1361 Query: 3369 IIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKF 3428 + A+KA+ LQS+ YKSDL MKGIGW+ + S ++ AK+AGEL+S+T YR++P+++KF Sbjct: 1362 MAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKF 1421 Query: 3429 TSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIH---VMPDTPEIMLAKLNRINYSDK 3485 T++ D+P+ V AKN+ ++ N+R+Y D +++H ++PD P+ A+LN ++ SDK Sbjct: 1422 TTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDK 1478 Query: 3486 LYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPK 3545 +Y+ + E+++ YD RLDAIP Q A+ASR+IASD++YKE + + G IG R++ DDP+ Sbjct: 1479 VYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPR 1538 Query: 3546 MMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTC 3605 M ++V ++QSD EYKK+F K +++F S D G++ AK+ Q L SD+ Y+ PL + TC Sbjct: 1539 MKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTC 1598 Query: 3606 LPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDR 3660 P+Q + A+KA+ LQSD YKSDL RG+GW P GS +VE +RA E+ + R Sbjct: 1599 DPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANAR 1653 Score = 1004 bits (2595), Expect = 0.0 Identities = 571/1519 (37%), Positives = 894/1519 (58%), Gaps = 69/1519 (4%) Query: 2433 EKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIH 2492 E K E +E Y QP + F ++ K N + S Y+ D+ ++ Sbjct: 148 EARKSLGEEYTED-YEQPRGKGSFPAMITPAYQRAKKAN-QLASQVEYKRGHDERISRFS 205 Query: 2493 IMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYK 2552 + DTP+++ +KA SD Y YE+ + KG + + AK + E+AS+ +Y Sbjct: 206 TVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYH 265 Query: 2553 EGFRKQL----GHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLG 2608 + ++K++ G IGA I Q + Y +++E+ + K S P + Sbjct: 266 QQYQKEMRGMAGPAIGAEGI--------LTRECADQYGQGYPEEYEEHRGKGSFPAMITP 317 Query: 2609 VVL-AKKCQTLVSDVDYKNYLHQ------WTCLPDQSDVI--HARQAYDLQSDNLYKSDL 2659 AKK L SD+ Y+ ++ + LP Q +++ A+ L S+N YK + Sbjct: 318 AYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENY 377 Query: 2660 Q-----WLKGIGW-------MTSGSLED-------------EKNKRATQI---------- 2684 Q +G+G M GSL + N AT Sbjct: 378 QNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLV 437 Query: 2685 -LSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEV 2743 L D YRQ D+ K+SS+ D+ +V AK NA ++H Y ++K+K + D P++ Sbjct: 438 PLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQL 497 Query: 2744 LLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLG 2803 + AK N +SE YK G E+ K KG++M++DA+ + AAKAS ++AS KYKE Y K G Sbjct: 498 VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 557 Query: 2804 HHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVS 2863 +G D +++ S+ +AK+ S+ EYKK FE+ KT+F P+DM+ + AKK QTL S Sbjct: 558 KAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLAS 613 Query: 2864 DVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKR 2923 D+DY+ LH++T LP+ A++AY LQS+ YK+DL WM+G+GW++ GSL++E+ K+ Sbjct: 614 DLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKK 673 Query: 2924 ATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDT 2983 A +++S+K YRQ D KFTSVTDS + AK + + Y ++ Q I D Sbjct: 674 AGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 733 Query: 2984 PEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRK 3043 P + AR N N SE LYK + E K KG++LR D++ +AAKA RD+ S+ KYK+ Y + Sbjct: 734 PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYER 793 Query: 3044 QLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQT 3103 G IGA++++ D +M S+ ++K+QS+ EYKK FE K++ +DM+ +V A+K Q Sbjct: 794 SRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQH 853 Query: 3104 LVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVK 3163 L +DV YK H +T LP V A++AY LQSDN Y++D++W++G+GWV GS++V + Sbjct: 854 LATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQ 913 Query: 3164 CKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIM 3223 K+A E++S+ YRQ PD LKFTS+ D+ E V A+ + RLY E + K Sbjct: 914 AKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPT 973 Query: 3224 PDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEA 3283 D PE++LA+ N +N SE+ Y+++ + + GY LR DA+P AAKAS +I SDYKYKEA Sbjct: 974 ADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEA 1033 Query: 3284 YRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKK 3343 + K G +G+R++ DD + S++ +QSD YKK FE K ++ P+DM +V AKK Sbjct: 1034 FEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKK 1093 Query: 3344 CQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLE 3403 QTL S+ DYKHPL ++ L + + A+KA+ LQS+NLY+SDL +M+G+ V +LE Sbjct: 1094 AQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLE 1153 Query: 3404 VVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTI 3463 + K+A EL+S++ YRQ P + K+T++TDTP + AK + N+RLY A ++ + Sbjct: 1154 IEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEY 1213 Query: 3464 HVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKY 3523 + PE + AK N N SD YK + + +GY L ++A+P QAA+AS DIASD+ Y Sbjct: 1214 TMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLY 1273 Query: 3524 KEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVL 3583 + + K+ G IG ++++DDP++ + ++QS+ +Y++ + +F P+DM+ +V Sbjct: 1274 RHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVH 1333 Query: 3584 AKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIG 3643 AK Q L SD DY+ H++T LP+ + A+KA+ LQS+ YKSDL ++GIGW+ + Sbjct: 1334 AKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALR 1393 Query: 3644 SVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADK 3703 S ++E K+AGE++S+ KYR+ D +KFT + D+P++V AKN+ + ++ +Y D Sbjct: 1394 SPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDA 1450 Query: 3704 TSIH---VMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDI 3760 S+H ++PD PD A+ N+ ++S K+Y W++++ YD R DAI ++A+ASR+I Sbjct: 1451 ESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREI 1510 Query: 3761 ASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVD 3820 ASD++YKEA+ + +G IG +S++DDP++ ++ G++QS+ EYKK+F K +++F S D Sbjct: 1511 ASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTD 1570 Query: 3821 MLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGI 3880 +L AK+ Q L +D+ YR L + TC P+Q + A+KA+ LQSD YK+DL RG+ Sbjct: 1571 QPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGV 1630 Query: 3881 GWMPQGSPEVLRVKNAQNI 3899 GW P GS +V + A + Sbjct: 1631 GWTPPGSYKVEMARRAAEL 1649 Score = 967 bits (2499), Expect = 0.0 Identities = 555/1472 (37%), Positives = 860/1472 (58%), Gaps = 68/1472 (4%) Query: 2723 YTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAA 2782 Y D+ + + DTPE+L +K S+ Y E+ + KG + + A Sbjct: 193 YKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIA 252 Query: 2783 KASRDIASEFKYKEGYRKQL----GHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEK 2838 K + ++AS+ +Y + Y+K++ G IGA I Q + Y +++E+ Sbjct: 253 KRANELASDVRYHQQYQKEMRGMAGPAIGAEGILT--------RECADQYGQGYPEEYEE 304 Query: 2839 WKTKFSSPVDMLGVVL-AKKCQTLVSDVDYKNYLHQ------WTCLPDQSDVI--HARQA 2889 + K S P + AKK L SD+ Y+ ++ + LP Q +++ A+ Sbjct: 305 HRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSV 364 Query: 2890 YDLQSDNMYKSDLQ-WMRG-----------IGWVSIGSLDVEKCKRATEI---------- 2927 L S+N YK + Q MRG + + +GSL +A Sbjct: 365 NKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPA 424 Query: 2928 --------------LSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKD 2973 L D YRQ D+ K++SVTD+ + V AK NA ++ Y ++K+ Sbjct: 425 TLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKN 484 Query: 2974 KTQIHIMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVIS 3033 K + D P+++ A+ N +SE YK E+ K KG++++ DA+ ++AAKAS ++ S Sbjct: 485 KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELAS 544 Query: 3034 DYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDML 3093 + KYK+ Y K G +G D +++ S+ +AK+ S+ EYKK FE+ KT+F P+DM+ Sbjct: 545 NIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMV 600 Query: 3094 GVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGW 3153 + AKK QTL SD+DY+ LHE+T LP+ A++AY LQS+ YK+DL W++G+GW Sbjct: 601 NIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGW 660 Query: 3154 VPIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAW 3213 + GS+++ + K+A +++S+ YRQ D+LKFTSVTDS + AK + + Y Sbjct: 661 LTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGN 720 Query: 3214 DKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRD 3273 ++ Q I D P + AR N N SE LY+ + E K +G++LR D++ +AAKA RD Sbjct: 721 EQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRD 780 Query: 3274 IASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPV 3333 +AS+ KYKE Y + G IGA+ V D ++ SL ++K+QS+ EYKK FE K++ + Sbjct: 781 LASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSL 840 Query: 3334 DMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKG 3393 DM+ +V A+K Q L +DV YK H + LP + A+KAY LQSDN Y++D++WMKG Sbjct: 841 DMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKG 900 Query: 3394 IGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYT 3453 +GWV SL V +AK+AGEL+S+ YRQ P+ LKFTSI DTPE V A+ + RLY Sbjct: 901 MGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYR 960 Query: 3454 EAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKA 3513 E +N K D PE++LAKLN +N S+ YK + + + GY LRLDA+P QAAKA Sbjct: 961 EQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKA 1020 Query: 3514 SRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFS 3573 S +I SDYKYKE + K G +G+R+++DD + S++ +QSD YKK FE K +F Sbjct: 1021 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1080 Query: 3574 SPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEW 3633 P+DM +V AKK Q L S+ DYKHPL ++T L + + A+KA+ LQS+ +Y+SDL + Sbjct: 1081 LPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNF 1140 Query: 3634 LRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKH 3693 +RG+ V G++E+E K+A E++S+ KYRQ K+T +TDTP ++ AK + ++ Sbjct: 1141 MRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNER 1200 Query: 3694 LYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKS 3753 LY A + + + P+ + AK+N+AN+S Y + W + + Y L +A+ ++ Sbjct: 1201 LYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQA 1260 Query: 3754 AKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKT 3813 A+AS DIASD+ Y+ + K++G IG QS+ DDP+I G++QSE +Y++ + Sbjct: 1261 ARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQA 1320 Query: 3814 KFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKAD 3873 +F P+DM+ ++ AK Q L +D DYR H++T +P+ + AKKA+ LQS+ YK+D Sbjct: 1321 QFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSD 1380 Query: 3874 LEWLRGIGWMPQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENI 3933 L ++GIGW+ SP++ K A + ++ YR ++K+T++VD+P++V AK++ + Sbjct: 1381 LIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHC 1440 Query: 3934 SIPKYREVWDKDKTSIH---IMPDTPEINLARANALNVSNKLYREGWDEMKAGC-DVRLD 3989 + YR D S+H ++PD P+ AR NAL++S+K+YR W++ +AG D RLD Sbjct: 1441 NERMYR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLD 1497 Query: 3990 AIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLD 4049 AIP Q A+ASREIASD++YK + +G +G + DD +++ L +LQ++ EY+ D Sbjct: 1498 AIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKD 1557 Query: 4050 WAKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSD 4109 +AK +++ S D +L +K SQ L SD+ YR L Q TC P+Q + A+KA++LQSD Sbjct: 1558 FAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSD 1617 Query: 4110 NVYKADLEWLRGIGWMPNDSVSVNHAKHAADI 4141 YK+DL RG+GW P S V A+ AA++ Sbjct: 1618 VKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1649 Score = 803 bits (2075), Expect = 0.0 Identities = 475/1446 (32%), Positives = 793/1446 (54%), Gaps = 35/1446 (2%) Query: 39 TSDYEQS--ETSKPALAQPA--LAQPASAKPVERRKVIRKKVDPSKFMTPYIAH----SQ 90 T DYEQ + S PA+ PA +A+ A+ + R + + + P I ++ Sbjct: 229 TEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTR 288 Query: 91 KMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHV 150 + D + Y E++E+ +G+ TP + KK + S++KYR D + K H Sbjct: 289 ECADQYGQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHY 347 Query: 151 DE-KAKD---IEHAKKVSQQVSKVLYKQNWED-TKDKYLLPPDAPELVQAVKNTAMFSKK 205 A+D ++ A+ V++ VS+ YK+N+++ + +Y + A+K ++ S Sbjct: 348 HSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNV 407 Query: 206 LYTEDWEAD-KSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEF 264 Y D++ D YP +P + A L D Y++ + + +++ + D P I Sbjct: 408 AYKADYKHDIVDYNYPATLTPSY-QTAMKLVPLKDANYRQSI--DKLKYSSVTDTPQIVQ 464 Query: 265 AKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQIY 324 AK Q+S Y+ DYE ++ A+ NA S KY+E +E K + + Sbjct: 465 AKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGF 524 Query: 325 FMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSD 384 M+ + K +G AS +KYKE+YEK KGKA + +++ L L+ A S+ Sbjct: 525 EMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA----MGTADSRLLHSLQIA-KMSSE 579 Query: 385 KLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHS 444 YK+ +E++K + + + Q +SD Y+ L Y ED Sbjct: 580 VEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKK-----LHEYTVLPEDMKTQ 634 Query: 445 HCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTQ 504 K S+ YKA+ +G G+ + +A K + Y+ D+ KFT Sbjct: 635 WAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTS 694 Query: 505 VTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSDNLYKQD 564 VTDS + A+ + + S + YKA +E + I D P F+Q + NA NLS+ LYK Sbjct: 695 VTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSS 754 Query: 565 WEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSL 624 WE KAK F++++D++ LAAKA S+V YK+DYE+++GK+IG + D +M HSL Sbjct: 755 WENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSL 814 Query: 625 KVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEARYKDLYVKDVLGHYVGS 684 +++K QS+ YK+ +E TK++ C + ++ D+ K H+ Sbjct: 815 QMSKLQSELEYKKGFEDTKSQ----CHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 870 Query: 685 MEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKLDQCKDHTYKVHP 744 D K SD Y+A+ + KG + +A K + + Y+ HP Sbjct: 871 PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 930 Query: 745 DKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLS 804 D KFT++ D+P ++QA+++ Q D Y+ + E K AD P+ + ++NA N+S Sbjct: 931 DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 990 Query: 805 DNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDD 864 + YK+ W K + + +++DA+P AAKA+ + SD YK+ +EK KG+M+G+ S+ DD Sbjct: 991 ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1050 Query: 865 PKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILHSY 924 + HS+ QSD Y+K +E SK + PLDM + AKK+Q +AS+ DYKH L Y Sbjct: 1051 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1110 Query: 925 SYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASDILNEKKY 984 + + + + AKKA+ LQS+ Y++D N +M+G V G+LE+E K+AS++++E KY Sbjct: 1111 TSLAEDLRLSCAKKAHKLQSENLYRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKY 1169 Query: 985 RQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNA 1044 RQHP + K+T++ D P + +K + ++ YKA GE+ H+Y + LP+FI+AK NA Sbjct: 1170 RQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNA 1229 Query: 1045 YNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQS 1104 N+S+ YK ++L +GY L +A+P +AA+A+ ASD Y+ D+ K +GK++G QS Sbjct: 1230 ANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQS 1289 Query: 1105 LQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVSNVNYKHS 1164 ++DDP++ H + ++QS+ +Y++ ++++++ P DM ++V AK AQ + S+ +Y+ Sbjct: 1290 VRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQ 1349 Query: 1165 LHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDALN 1224 H +T LP+ + + +K +QS+ YK D MKGIGW+ + S +E KKAG+ ++ Sbjct: 1350 YHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIGWLALRSPQMESAKKAGELIS 1408 Query: 1225 EKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQA 1284 E KYR+ PD++KFT++VDSP +V AK + ++ +Y++ + H+YT+ PD P F +A Sbjct: 1409 ETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRA 1468 Query: 1285 KCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKGKHV 1344 + NA ++SD Y+ W A + DAIP A+ASR IASD++YKEA+ + +G + Sbjct: 1469 RLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQI 1528 Query: 1345 GFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVATNVN 1404 G+RS+ DDP++ H++NV +LQSD EYKK++ +++ +H+ D + AK +Q +A++V+ Sbjct: 1529 GYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVH 1588 Query: 1405 YKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVKKAG 1464 Y+QPL T P+ + L H + +Q+QSD YK + N +G+GW P GS +VE ++A Sbjct: 1589 YRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLN-LTRGVGWTPPGSYKVEMARRAA 1647 Query: 1465 DALNER 1470 + N R Sbjct: 1648 ELANAR 1653 Score = 753 bits (1945), Expect = 0.0 Identities = 483/1524 (31%), Positives = 809/1524 (53%), Gaps = 50/1524 (3%) Query: 3363 LPDQNDI--IHARKAYDLQSDNLYKSDLEWMKGIGWVP-IDSLEVVRAKRAGELLSDTIY 3419 LPD + + ARK+ + Y D E +G G P + + RAK+A +L S Y Sbjct: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193 Query: 3420 RQRPETL--KFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAK 3476 ++ + +F+++ DTPE + +K A + YTE ++ + K TP +AK Sbjct: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAK 253 Query: 3477 LNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIG 3536 SD Y ++ +KE + AI + +R+ A +Y +GY ++ H G Sbjct: 254 RANELASDVRYH---QQYQKEMRGMAGPAIGAEGI-LTRECAD--QYGQGYPEEYEEHRG 307 Query: 3537 ARNIKD--DPKMMWSIHVAKIQSDREYKKEFEKWKTK---FSSPV-DMLGVVLAKKCQIL 3590 + P + ++ SD +Y+++F K K S P D L + A+ L Sbjct: 308 KGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKL 367 Query: 3591 VSDIDYK-----HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSD-----LEWLRGIGWV 3640 VS+ YK H + + + A K L S+ YK+D +++ Sbjct: 368 VSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLT 427 Query: 3641 PIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWD 3700 P ++ V L D YRQ D+LK++ +TDTP+IV AK NA +S Y ++ Sbjct: 428 PSYQTAMKLVP-----LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYE 482 Query: 3701 ADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDI 3760 +K + + D P ++ AK+N+ S+ Y +GW+++K K ++++ DA+S+ +AKAS ++ Sbjct: 483 KNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGEL 542 Query: 3761 ASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVD 3820 AS+ KYKE YEK KG +G D +++ ++ K+ SE EYKK F++ KT+F P+D Sbjct: 543 ASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMD 598 Query: 3821 MLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGI 3880 M++I AKK QTL +D+DYR LHE+T +P+ AKKAY LQS+ YKADL W++G+ Sbjct: 599 MVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGV 658 Query: 3881 GWMPQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYRE 3940 GW+ +GS + + K A + + YR V LK+TS+ D+ ++ AK + E S Y+ Sbjct: 659 GWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKA 718 Query: 3941 VWDKDKTSIHIMPDTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKAS 3999 ++ I D P ARANA N+S KLY+ W+ KA G ++RLD++ AAKA Sbjct: 719 GNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAK 778 Query: 4000 REIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQS 4059 R++AS+ KYK D+E+ +G +G + D+++ +L KLQ+E EY+ + K++ Sbjct: 779 RDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHV 838 Query: 4060 PVDMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWL 4119 +DM+ ++H++ +Q L +D+ Y+ H +T +P V AKKAY LQSDN Y+AD++W+ Sbjct: 839 SLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWM 898 Query: 4120 RGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIK 4179 +G+GW+ S++V AK A ++ SEKKYR + L FT + D + V A+ S D Sbjct: 899 KGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRL 958 Query: 4180 YRKDWNATKSKYTLT-ETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHA 4238 YR+ K YT T + P + A+ A + + YKE W + + GY L DA+PF A Sbjct: 959 YREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAA 1018 Query: 4239 HHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAK 4298 ++ S+ KYK K KG +G ++ DD L +A +Q++ YK+ + +KA+ Sbjct: 1019 KASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQ 1078 Query: 4299 INIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADL 4358 ++P DM +++ AK+ QTL S+ DY++ L Q+ + + A+KA+ LQS+N+YR+DL Sbjct: 1079 FHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL 1138 Query: 4359 EWLRGIGWIPLDSVDHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVN 4418 ++RG+ + +++ K E++S+ KY+++ + + +V D P ++ AK ++ Sbjct: 1139 NFMRGVACVIPGTLEIEGRKKASELISESKYRQH--PHSFKYTAVTDTPNLLHAKFSNQI 1196 Query: 4419 QSDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYI 4478 ++ YK A+ +YT + P +K S YK +W +A GY L + Sbjct: 1197 TNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEAL 1256 Query: 4479 PIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYE 4538 P A+ + + S+ Y+ + K++G + + + + P + HC +++S L YR+ Sbjct: 1257 PFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGAT 1316 Query: 4539 DTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNV 4598 ++A H+P DM++ V AK Q + SD +YR +H++T+L E+ + + A + S+ Sbjct: 1317 SSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELR 1376 Query: 4599 YKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAV 4658 YK DL +KGIG +PQ+ AKK+ +L S+ +Y K + + V D+P V A Sbjct: 1377 YKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRK--KPDSIKFTTVVDSPDLVHAK 1434 Query: 4659 QSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYIL 4718 S ++ +E Y+ + +YT + + D+ R R S +Y+ +W++ +A SY Sbjct: 1435 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1494 Query: 4719 PSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLY 4778 + A+ + +AS +Y+E + + + L RSVDDDP L VG+L D Y Sbjct: 1495 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1554 Query: 4779 RSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQ 4838 + + K++ + H D ++ AK SQ+ S++ YR L + C P+ H +K Sbjct: 1555 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQL 1614 Query: 4839 ISDIVYKDDLNWLKGIGCYVWDTP 4862 SD+ YK DLN +G+G W P Sbjct: 1615 QSDVKYKSDLNLTRGVG---WTPP 1635 Score = 630 bits (1625), Expect = e-179 Identities = 452/1581 (28%), Positives = 756/1581 (47%), Gaps = 234/1581 (14%) Query: 3150 GIGWVP--IGSMDVVKCKRAAEILSDNI---YRQPPDKLKFTSVTDSLEQVLAKNNALNM 3204 G W P + ++V+ A + L + Y QP K F ++ Q K N L Sbjct: 130 GNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLAS 189 Query: 3205 NKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIP 3264 Y D+ ++ + DTPE++ ++ S+ Y + E+ + +G Sbjct: 190 QVE-YKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248 Query: 3265 IVAAKASRDIASDYKYKEAYRKQL----GHHIGARAVHDDPKIMWSLHIAKVQSDREYKK 3320 AK + ++ASD +Y + Y+K++ G IGA + Q + Y + Sbjct: 249 YQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGI--------LTRECADQYGQGYPE 300 Query: 3321 DFEKYKTRYSSPVDMLGIVL-AKKCQTLVSDVDYKHPLHE------WICLPDQNDII--H 3371 ++E+++ + S P + AKK L SD+ Y+ ++ + LP Q++++ Sbjct: 301 EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ 360 Query: 3372 ARKAYDLQSDNLYKSDLE-----WMKGIGWVPIDSLEVVRAKRAGEL------------- 3413 A+ L S+N YK + + +G+G + A + G L Sbjct: 361 AQSVNKLVSENKYKENYQNHMRGRYEGVGM----DRRTLHAMKVGSLASNVAYKADYKHD 416 Query: 3414 ----------------------LSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRL 3451 L D YRQ + LK++S+TDTP+ V AK NA ++ Sbjct: 417 IVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVN 476 Query: 3452 YTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAA 3511 Y ++ +K + D P+++ AK N +S+ YK E++K +G++++LDA+ + AA Sbjct: 477 YRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 536 Query: 3512 KASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTK 3571 KAS ++AS+ KYKE Y K G +G D +++ S+ +AK+ S+ EYKK FE+ KT+ Sbjct: 537 KASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR 592 Query: 3572 FSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDL 3631 F P+DM+ + AKK Q L SD+DY+ LHE+T LP+ A+KAY LQS+ YK+DL Sbjct: 593 FHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL 652 Query: 3632 EWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMS 3691 W++G+GW+ GS+ +E+ K+AG+++S++ YRQ D+LKFT +TD+ ++ AK + S Sbjct: 653 AWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQS 712 Query: 3692 KHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISI 3751 Y + + D P L A++N+AN+S+KLY W+ K K ++LR D+++ Sbjct: 713 GVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTF 772 Query: 3752 KSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKW 3811 +AKA RD+AS+ KYKE YE+ +G IGA+ ++ D ++ ++ K+QSE EYKK F+ Sbjct: 773 LAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDT 832 Query: 3812 KTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYK 3871 K++ +DM+ ++ A+K Q L TD+ Y+ H +T +P + AKKAY LQSD Y+ Sbjct: 833 KSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYR 892 Query: 3872 ADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAE 3931 AD++W++G+GW+ GS V + K A + + YR LK+TSI DTPE+V A+ + Sbjct: 893 ADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYT 952 Query: 3932 NISIPKYREVWDKDKTSIHIMPDTPEINLARANALNVSNKLYREGWDEMK-AGCDVRLDA 3990 YRE + K D PE+ LA+ NA+N+S Y+E W +++ G +RLDA Sbjct: 953 QAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDA 1012 Query: 3991 IPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDW 4050 +P QAAKAS EI SDYKYK EK KG +G+ + DD + ++ A LQ++ Y+ + Sbjct: 1013 LPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGF 1072 Query: 4051 AKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDN 4110 KA+ P+DM +++H+K +Q L S+ DY++ L Q+T + + + AKKA++LQS+N Sbjct: 1073 EHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSEN 1132 Query: 4111 VYKADLEWLRGIGWM---------------------------------PNDSVSVNHAKH 4137 +Y++DL ++RG+ + D+ ++ HAK Sbjct: 1133 LYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKF 1192 Query: 4138 AADIFSEKKYRTKIETLN--FTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSK-YTLT 4194 + I +E+ Y+ E +T +++ AK + L D +Y++ W +++ Y LT Sbjct: 1193 SNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLT 1252 Query: 4195 ETPL-LHTAQEAARILDQYLYKEGW--ERQKATG-------------------------- 4225 L A+ + I +LY+ + ER K G Sbjct: 1253 IEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1312 Query: 4226 ---------YILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWF 4276 + LP D V VHA + + S+ Y+ ++ K + +P +D K+ W Sbjct: 1313 RGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK----FTALP---EDLKMAWA 1365 Query: 4277 EHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNY---------- 4326 + A +Q+E YK D K + + +AK+ L+S+ YR Sbjct: 1366 KKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVV 1425 Query: 4327 ---------------------------LHQWMCHPDQNDVIQARKAYDLQSDNVYRADLE 4359 LH++ PD D +AR SD VYR E Sbjct: 1426 DSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWE 1485 Query: 4360 WLRGIGW-IPLDSVDHVRVTKNQEMMSQIKYKKNALENYP---NFRSVVDPPEIVLAKIN 4415 R + LD++ ++E+ S +YK+ L + +RSV D P + Sbjct: 1486 QTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNV 1545 Query: 4416 SVNQSDVKYKETFNKAKGKYTFSPDTPHI------------------------------- 4444 QSD +YK+ F K++ ++ S D P + Sbjct: 1546 GRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGL 1605 Query: 4445 SHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNS-----ELKYKETY 4499 H++ +L S + YK T+ G+T Y + + A+L N+ + Y+ Sbjct: 1606 RHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAE 1665 Query: 4500 EKQKGHYLAGKVIGEFPGVVH 4520 + G + +G+V + ++H Sbjct: 1666 AVEAGDHQSGEVNPDATEILH 1686 Score = 436 bits (1122), Expect = e-121 Identities = 387/1490 (25%), Positives = 667/1490 (44%), Gaps = 101/1490 (6%) Query: 4165 YVTAKQSGEILDDIKYRKDWNATKSKY-TLTETPLLHTAQEAARILDQYLYKEGWERQKA 4223 Y AK++ ++ ++Y++ + S++ T+ +TP L ++ A++ Y E +E+Q+ Sbjct: 178 YQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRG 237 Query: 4224 TGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQ 4283 G + A N++ S+++Y ++ K+ G + ++ E A Q Sbjct: 238 KGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEG--ILTRECADQYG 295 Query: 4284 NERLYKEDYHKTKAKINIPADMVSVLA-AKQGQTLVSDIDYRNYLHQ------WMCHPDQ 4336 Y E+Y + + K + PA + AK+ L SDI YR ++ + P Q Sbjct: 296 QG--YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353 Query: 4337 NDVI--QARKAYDLQSDNVYRADLE-WLRG-IGWIPLDSVDHVRVTKNQEMMSQIKYKKN 4392 ++++ QA+ L S+N Y+ + + +RG + +D + K + S + YK + Sbjct: 354 DNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRT-LHAMKVGSLASNVAYKAD 412 Query: 4393 ALE-----NYP-------------------NFR---------SVVDPPEIVLAKINSVNQ 4419 NYP N+R SV D P+IV AKIN+ Sbjct: 413 YKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQL 472 Query: 4420 SDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIP 4479 S V Y+ + K K YT D P + +K KL+S + YK WE TK G+ + + Sbjct: 473 SHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMS 532 Query: 4480 IVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPG-VVHCLDFQKMRSALNYRKHYE 4538 ++ AK + + S +KYKE YEK KG K +G ++H L KM S + Y+K +E Sbjct: 533 LLAAKASGELASNIKYKEEYEKTKG-----KAMGTADSRLLHSLQIAKMSSEVEYKKGFE 587 Query: 4539 DTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNV 4598 ++K H+P DM+N AK+ Q + SDL+YR H++T L E+ + A + S+ Sbjct: 588 ESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQ 647 Query: 4599 YKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAV 4658 YK DL W+KG+G + + AKK+ L S+ Y E + VTD+ A Sbjct: 648 YKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDE--LKFTSVTDSSQMEHAK 705 Query: 4659 QSGINASEVKYKENYHQIKDKYTTVLETVDYDRTR-NLKNLYSSNLYKEAWDRVKATSYI 4717 +S S V YK Q +YT + + + R N NL S LYK +W+ KA + Sbjct: 706 KSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANL-SEKLYKSSWENQKAKGFE 764 Query: 4718 LPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRL 4777 L +L+ AK ++ LAS +KY+E+YE+ + + V D + L++ KL + Sbjct: 765 LRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELE 824 Query: 4778 YRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTD 4837 Y+ +E K + H+ DMV +V A+ +Q +++ Y+ H + P + +K Sbjct: 825 YKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYG 884 Query: 4838 QISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTP 4897 SD Y+ D+ W+KG+G + + AK A +L + KY+ H + + + DTP Sbjct: 885 LQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALK--FTSIKDTP 942 Query: 4898 VYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNL----YKTS 4953 VQA S Q D +Y + +++ P T DL L A KL + N+ YK S Sbjct: 943 EMVQARISYTQAVDRLYR-EQGENIKHHYTP---TADLPEVLLA-KLNAMNISETRYKES 997 Query: 4954 LRTL-PTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPK----DVPFVH 5008 L GY+L D F+ K + + S +KYKEA+E K G LG + D+ H Sbjct: 998 WSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK--GQMLGSRSLEDDISLAH 1055 Query: 5009 VRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMI 5068 ++ S+ Y++ + K + H D + KK Q S YK Sbjct: 1056 SVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPL----PQYT 1111 Query: 5069 SLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTD 5128 SL ++ + + S+ Y+ DL ++G C + T ++ + +L S Y Sbjct: 1112 SLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ 1171 Query: 5129 KARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQ 5188 KY V DTP + +E +Y+AAG+ + +T P+ +RAK Sbjct: 1172 HPHSF--KYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNA 1229 Query: 5189 KLQSQYLYVELATKERPH-HHAGNQTTALKHAKDVKDMVSEKKYKIQYEKMKDKY---TP 5244 S Y E R + + + A+ D+ S+ Y+ + K + K Sbjct: 1230 ANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQS 1289 Query: 5245 VPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKEN 5304 V D P + +R S+L+Y+ ++ ++H D + +V+ + + + + Sbjct: 1290 VRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAK----NAQALASDHD 1345 Query: 5305 YMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKT 5364 Y +Q + ++P+ + + S+++YK DL +KGIG A +P A+K Sbjct: 1346 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1405 Query: 5365 LYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEP 5424 L S+ KY++ + K F V DSP H K + NE+ YR+ + +Y L+ D P Sbjct: 1406 LISETKYRKKPDSIK--FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHP 1463 Query: 5425 RHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQI-SDILYKLEY--N 5481 A+ +S YR ++E+++ +T + +++I SD YK + + Sbjct: 1464 DFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRD 1523 Query: 5482 KAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKV 5541 + GY ++ D P + H V SD +YK+ + +++S D + AK + ++ Sbjct: 1524 RGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQL 1583 Query: 5542 NTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKG 5591 +++ Y++ P++ A K+ QSD +YK D +G Sbjct: 1584 ASDVHYRQPLPQPTC----DPEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1629 Score = 350 bits (898), Expect = 3e-95 Identities = 398/1633 (24%), Positives = 681/1633 (41%), Gaps = 179/1633 (10%) Query: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY-VWDTPQILHAKKSYDLQSQLQYTAA 4637 L +P ++R+ A++ L + Y +D +G G + TP AKK+ L SQ++Y Sbjct: 138 LPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196 Query: 4638 GKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYT-TVLETVDYDRTRNLK 4696 E + ++ V DTP + + S+V+Y E+Y Q + K + + T Y + Sbjct: 197 HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRAN 256 Query: 4697 NLYSSNLYKEAWD---RVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTL 4753 L S Y + + R A I L+ A Y EEYE+ + + Sbjct: 257 ELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQ-----GYPEEYEEHRGKGSF 311 Query: 4754 PRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHI----VPDMVEMVTAKDSQKKVS 4809 P + A+ + +L D YR + K K H D + + A+ K VS Sbjct: 312 PAMITPAYQNAK--KAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369 Query: 4810 EIDYRLRLHEWICHPDLQVND-----HVRKVTDQISDIVYKDDLNWLKGIGCYVWD---T 4861 E Y+ + V H KV S++ YK D + I Y + T Sbjct: 370 ENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKAD--YKHDIVDYNYPATLT 427 Query: 4862 PEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHS 4921 P A L+D Y+ + K + Y VTDTP VQA + +QLS Y DY + Sbjct: 428 PSYQTAMKLVPLKD-ANYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKN 484 Query: 4922 VRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSL-RTLPTGYRLPGDTPHFKHIKDTRYMS 4980 P L +A KL S YK +T G+ + D K + ++ Sbjct: 485 KLNYTLPQD-VPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELA 543 Query: 4981 SYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPE 5040 S KYKE YE TK G +G D +H ++ ++SE Y++ + + K + H D Sbjct: 544 SNIKYKEEYEKTK--GKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVN 601 Query: 5041 IRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKG 5100 IR KK Q S+L Y+ K+ + + LP + + + S+++YK DL +KG Sbjct: 602 IRHAKKAQTLASDLDYRK---KLHEYTV-LPEDMKTQWAKKAYGLQSELQYKADLAWMKG 657 Query: 5101 FGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELV 5160 G + ++ +++ +L S Y + ++ K+ V D+ + ++ + S + Sbjct: 658 VGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL--KFTSVTDSSQMEHAKKSQELQSGVA 715 Query: 5161 YRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQTTALKHA 5219 Y+A ++ +T D P L+A+ S+ LY ++ + A Sbjct: 716 YKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAA 775 Query: 5220 KDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNA---SDLRYKETFQKTKGK 5276 K +D+ SE KYK YE+ + K D + + + S+L YK+ F+ TK + Sbjct: 776 KAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQ 835 Query: 5277 YHTVKDALDIVYHRKVTDDISKIKYK--ENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDV 5334 H D + +V+ RK + + YK E++ + L P + + SD Sbjct: 836 CHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL------PTDMKVEWAKKAYGLQSDN 889 Query: 5335 KYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPIN-RH 5393 +Y+ D+ W+KG+G +VA +N Sbjct: 890 QYRADVKWMKGMG------------------------------------WVATGSLNVEQ 913 Query: 5394 FKYATQLMNEKKYRADYEQRKD--KYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK 5451 K A +L++EKKYR Q D K+ + D P + A+ + Q YR+ E K Sbjct: 914 AKKAGELISEKKYR----QHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH 969 Query: 5452 FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLK 5511 +T D PE L IS+ YK ++K + GY D + + +SD K Sbjct: 970 YTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYK 1029 Query: 5512 YKEVYQRNKSNC----TIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDF 5567 YKE +++ K ++E D + + + A + ++++YKK +E +KA + D Sbjct: 1030 YKEAFEKMKGQMLGSRSLEDD-ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAAL 1088 Query: 5568 LQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGT 5627 + A K+ S+ +YK S+ +D A + ++S+ Y+ RG Sbjct: 1089 VHAKKAQTLASNQDYKHPLPQYT----SLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1144 Query: 5628 CHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT 5687 +P T +I K S L+SE+KY+ H YT + +T + +H K + ++ Sbjct: 1145 ACVIPGTLEIEGRKKASELISESKYRQHPHSF----KYTAVTDTPNLLHAKFSNQITNER 1200 Query: 5688 NYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKK 5747 YK A +DA+ YT P+ + Sbjct: 1201 LYK----------------------------------AAGEDARHE--YTMTLGLPEFIR 1224 Query: 5748 ATQAAKQASEVEYRAKHRKEGSHGLSM-LGRPDIEMAKKAAKLSSQVKYRENFDKEKGKT 5806 A A S+ Y+ R + G + + + A+ + ++S YR +F KE+GK Sbjct: 1225 AKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKL 1284 Query: 5807 -PKYNPKDSQLYKVMKDANNLASEVKYK----ADLKKLHKPVTDMKESLIMNHVLNTSQL 5861 + +D + + L SE++Y+ + + H P+ + + + H N L Sbjct: 1285 IGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPM----DMVHLVHAKNAQAL 1340 Query: 5862 ASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPT 5921 AS + Y+ +Y K + +P++L+ K+A LQS ++YK +G L +P Sbjct: 1341 ASDHDYRTQYHK----FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1396 Query: 5922 YITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEES 5981 +AK++ ++ S +YRK +SIK T + +P L+H K + +E+ YR ES Sbjct: 1397 MESAKKAGELISETKYRKK-PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYRSGDAES 1452 Query: 5982 IRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNAT 6041 + T + D PD RA+ L++K Y+ E + + + + P F AR + Sbjct: 1453 LHR--YTLIPDHPDFTRARLNALHLSDKVYRNSWE-QTRAGSYDFRLDAIP-FQTARASR 1508 Query: 6042 DIASQIKYKQSAEMEKA---NFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETV 6098 +IAS +YK++ ++ + SV D P + H V L S +YK+D KS S + + Sbjct: 1509 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1568 Query: 6099 LDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNF---SSVLYK 6155 D P + + + +Q+ S + Y+ L PE L ++ QK S V YK Sbjct: 1569 TDQPGLLQAKRSQQLASDVHYRQPLPQP-------TCDPEQLGLRHAQKAHQLQSDVKYK 1621 Query: 6156 EDVSPGTAIGKTP 6168 D++ +G TP Sbjct: 1622 SDLNLTRGVGWTP 1634 Score = 321 bits (822), Expect = 2e-86 Identities = 402/1653 (24%), Positives = 692/1653 (41%), Gaps = 149/1653 (9%) Query: 4407 PEIVLAKINSVNQSDVKYKETFNKAKGKYTF-SPDTPHISHSKDMGKLYSTILYK-GAWE 4464 PEIV + + +Y E + + +GK +F + TP +K +L S + YK G E Sbjct: 141 PEIV-RMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199 Query: 4465 GTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVH---- 4520 + +D ++ +K + S+++Y E YE+Q+G G FP ++ Sbjct: 200 RISRFSTVVDTP--ELLRSKAGAQLQSDVRYTEDYEQQRGK-------GSFPAMITPAYQ 250 Query: 4521 -CLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRC-----QYILSDLEYRHYFHQ 4574 ++ S + Y + Y+ + P +L + C Q + E Sbjct: 251 IAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGS 310 Query: 4575 WTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY----VWDTPQILHAKKSYDLQS 4630 + +++ P + A E+ SD Y+ D N +KG Y D + A+ L S Sbjct: 311 FPAMIT-PAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369 Query: 4631 QLQYTAAGKENLQN-----YNLVTDTPLYVTAVQSGINASEVKYKENY-HQIKDKYTTVL 4684 + +Y KEN QN Y V + A++ G AS V YK +Y H I D Sbjct: 370 ENKY----KENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPAT 425 Query: 4685 ETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEY 4744 T Y L L +N Y+++ D++K +S + T + AK SH+ YR +Y Sbjct: 426 LTPSYQTAMKLVPLKDAN-YRQSIDKLKYSSV---TDTPQIVQAKINAQQLSHVNYRADY 481 Query: 4745 EKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMK-IHIVPDMVEMVTAKD 4803 EK K YTLP+ V P + KL + Y+ +EK K K + D + ++ AK Sbjct: 482 EKNKLNYTLPQDV---PQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKA 538 Query: 4804 SQKKVSEIDYRLRLHEWICHPDLQVND----HVRKVTDQISDIVYKDDLNWLKGIGCYVW 4859 S + S I Y+ +E + D H ++ S++ YK K Sbjct: 539 SGELASNIKYKEE-YEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPM 597 Query: 4860 DTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYV 4919 D I HAK A L D+ Y+ K ++Y ++ + A K+ S+ Y D Sbjct: 598 DMVNIRHAKKAQTLASDLDYR----KKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLA 653 Query: 4920 HSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYM 4979 ++G T +++L++A A +L S Y+ + L + D+ +H K ++ + Sbjct: 654 W-MKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELK--FTSVTDSSQMEHAKKSQEL 710 Query: 4980 SSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDK-IHTTPDT 5038 S YK E + + YT+ + F+ R SE+LY+ + K K D+ Sbjct: 711 QSGVAYKAGNEQS-VHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDS 769 Query: 5039 PEIRQVKKTQEAVSELIYKSDFFKMQGHMIS---LPYTPQVIHCRYVGDITSDIKYKEDL 5095 K ++ SE+ YK D+ + +G +I + Q+ H + + S+++YK+ Sbjct: 770 LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGF 829 Query: 5096 QVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTH 5155 + K C + + DMV H RK + +L TD K + + Sbjct: 830 EDTKS-QCHV--SLDMVHLVHARK--AQHLATDVGYKTAEHH------------------ 866 Query: 5156 LSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTA 5215 FT++P + AK+ LQS Y + + Sbjct: 867 ----------------FTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLN 910 Query: 5216 LKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKG 5275 ++ AK +++SEKKY+ + +K +T + DTP +++A+ +Y A D Y+E + K Sbjct: 911 VEQAKKAGELISEKKYRQHPDALK--FTSIKDTPEMVQARISYTQAVDRLYREQGENIKH 968 Query: 5276 KYHTVKDALDIVYHRKVTDDISKIKYKENYMS-QLGIWRSIPDRPEHFHHRAVTDTVSDV 5334 Y D +++ + +IS+ +YKE++ + G ++ D +A + +SD Sbjct: 969 HYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDY 1028 Query: 5335 KYKEDLTWLKG--IGCYAYDTPDFTLAEK--NKTLYSKYKYKEVFERTKSDFKYVADSPI 5390 KYKE +KG +G + + D +LA +L S YK+ FE +K+ F D Sbjct: 1029 KYKEAFEKMKGQMLGSRSLED-DISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAA 1087 Query: 5391 NRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKD 5450 H K A L + + DY+ +Y + ++ R AK A S+ YR + + Sbjct: 1088 LVHAKKAQTLASNQ----DYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRG 1143 Query: 5451 KFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDL 5510 I T E K ++ IS+ Y+ + K YT + DTP LLH + ++ Sbjct: 1144 VACVIPGTLEIEGRKKASELISESKYRQHPHSFK---YTAVTDTPNLLHAKFSNQITNER 1200 Query: 5511 KYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAH-WKWTPDRPDFLQ 5569 YK + + T+ AK ++ YK+ + +A +K T + F Sbjct: 1201 LYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQA 1260 Query: 5570 AAKSSLQQSDFEYKLDREFLKGCKL---SVTDDKNTVLALRNTLIESDLKYKEKHVKERG 5626 A S SDF Y+ D +G + SV DD R ++S+L+Y+ + Sbjct: 1261 ARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQA 1320 Query: 5627 TCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSD 5686 H D ++ AK L S++ Y+ K +T LPE K+ S+ Sbjct: 1321 QFHLPMDMVHLVHAKNAQALASDHDYRTQYHK------FTALPEDLKMAWAKKAHALQSE 1374 Query: 5687 TNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIK 5746 YK + KG + L P+++ A + + S+ YRK +++ +TTV D PD+ Sbjct: 1375 LRYKSDLIGMKGIG--WLALRSPQMESAKKAGELISETKYRKKP-DSIKFTTVVDSPDLV 1431 Query: 5747 KATQAAKQASEVEYRAKHRKEGSHGLSML-GRPDIEMAKKAAKLSSQVKYRENFDKEKGK 5805 A + +E YR+ E H +++ PD A+ A S YR ++++ + Sbjct: 1432 HAKNSYMHCNERMYRSGDA-ESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAG 1490 Query: 5806 TPKYNPKDSQLYKVMKDANNLASEVKYKADLKK---LHKPVTDMKESLIMNHVLNTSQLA 5862 + + D+ ++ + + +AS+ +YK + L + + M H LN +L Sbjct: 1491 SYDFR-LDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQ 1549 Query: 5863 SSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTY 5922 S +YKK + KS+ +H+ D L K + +L S V Y++ +P D E Sbjct: 1550 SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLP----QPTCDPEQLGL 1605 Query: 5923 ITAKESQQMQSGKEYRKDYEESIKGRNLT-GLEVT-PALLHVKYATKIASEKEYR-KDLE 5979 A+++ Q+QS +Y+ D NLT G+ T P V+ A + A R L+ Sbjct: 1606 RHAQKAHQLQSDVKYKSDL-------NLTRGVGWTPPGSYKVEMARRAAELANARGLGLQ 1658 Query: 5980 ESIRGKGLTEMEDTPDMLRAKNATQILNEKEYK 6012 + RG E D +AT+IL+ K+ K Sbjct: 1659 GAYRGAEAVEAGDHQSGEVNPDATEILHVKKKK 1691 Score = 318 bits (814), Expect = 1e-85 Identities = 387/1603 (24%), Positives = 669/1603 (41%), Gaps = 221/1603 (13%) Query: 5109 PDMVRSRHLRKLWSNYLYTDKARKMRDKYKV-VLDTPEYRKVQELKTHLSELVYRAAGKK 5167 P++VR RK YT+ + R K + TP Y++ ++ S++ Y+ + Sbjct: 141 PEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199 Query: 5168 QKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQTTALKHAKDVKDMV 5226 + S F++V DTP+LLR+K G +LQS Y E ++R T A + AK ++ Sbjct: 200 RISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELA 259 Query: 5227 SEKKYKIQYEK-------------------MKDKYT----------------PVPDTPIL 5251 S+ +Y QY+K D+Y P TP Sbjct: 260 SDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAY 319 Query: 5252 IRAKRAYWNASDLRYKETFQKTKGK--YHTV--KDALDIVYHRKVTDDISKIKYKENYMS 5307 AK+A+ ASD++Y++ F K KG YH++ +D L + + V +S+ KYKENY + Sbjct: 320 QNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQN 379 Query: 5308 QL-GIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYD---TPDFTLAEKNK 5363 + G + + H V S+V YK D + I Y Y TP + A K Sbjct: 380 HMRGRYEGVGMDRRTLHAMKVGSLASNVAYKAD--YKHDIVDYNYPATLTPSYQTAMKLV 437 Query: 5364 TLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDE 5423 L Y++ ++ K + V D+P K Q ++ YRADYE+ K Y L D Sbjct: 438 PLKDA-NYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDV 494 Query: 5424 PRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNK 5482 P+ + AKT S++KY++ +EK+K K F +D L + S+I YK EY K Sbjct: 495 PQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEK 554 Query: 5483 AKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVN 5542 K + T LLH ++ S+++YK+ ++ +K+ + D V+I+ AK A + Sbjct: 555 TKGKAMGTADSR--LLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 612 Query: 5543 TNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCK--------- 5593 ++LDY+K+ + P+ A K+ QS+ +YK D ++KG Sbjct: 613 SDLDYRKKLH----EYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNL 668 Query: 5594 ------------------------LSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCH 5629 SVTD A ++ ++S + YK + + Sbjct: 669 EQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYT 728 Query: 5630 AVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNY 5689 D P L A+ + +SE YK + A+G L ++ + K S+ Y Sbjct: 729 ISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRL-DSLTFLAAKAKRDLASEVKY 787 Query: 5690 KKKFVKEKGKSNYSIMLE-PPEVKHAMEVAKKQSDVAYRK---DAKENLH---------- 5735 K+ + + +GK + ++ ++ H+++++K QS++ Y+K D K H Sbjct: 788 KEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVH 847 Query: 5736 -------------------YTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLG 5776 +T + ++ A +A S+ +YRA + G G Sbjct: 848 ARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATG 907 Query: 5777 RPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKA-- 5834 ++E AKKA +L S+ KYR++ D K + K P+ Q + + A + Y+ Sbjct: 908 SLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQA----RISYTQAVDRLYREQG 963 Query: 5835 -DLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSK-GHYHTIPDNLEQLHLKE 5892 ++K + P D+ E L+ LN ++ + +YK+ + K + G Y D L K Sbjct: 964 ENIKHHYTPTADLPEVLLAK--LNAMNISET-RYKESWSKLRDGGYKLRLDALPFQAAKA 1020 Query: 5893 ATELQSIVKYKEKYEKERGKPMLDFETPTYITAKES---QQMQSGKEYRKDYEESIKGRN 5949 + E+ S KYKE +EK +G+ + I+ S +QS Y+K +E S K + Sbjct: 1021 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS-KAQF 1079 Query: 5950 LTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEK 6009 L++ AL+H K A +AS ++Y+ L + T + + + AK A ++ +E Sbjct: 1080 HLPLDMA-ALVHAKKAQTLASNQDYKHPLPQ------YTSLAEDLRLSCAKKAHKLQSEN 1132 Query: 6010 EYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEI 6069 Y+ DL RG+ + T + + A+++ S+ KY+Q K +T+V DTP + Sbjct: 1133 LYRSDLNFM---RGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK--YTAVTDTPNL 1187 Query: 6070 IHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKG- 6128 +HA+ +++++ YK E + Y L PE R + N N S +Y+ +N + Sbjct: 1188 LHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQ 1247 Query: 6129 --KITVVQDTPEILRVKENQKNFSSVLYKEDV--SPGTAIGKTPEMMRVKQTQDHISSVK 6184 K+T+ + + + S LY+ D G IG P+ +R Sbjct: 1248 GYKLTI--EALPFQAARASGDIASDFLYRHDFVKERGKLIG--PQSVR------------ 1291 Query: 6185 YKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTP----EIERVKRNQE 6240 D P ++ + + S + Y+ + P + K Q Sbjct: 1292 ------------DDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQA 1339 Query: 6241 NFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENM----GKGTPLAVTPEMER 6296 S Y+ K P +M K+ S + YK ++ G G +P+ME Sbjct: 1340 LASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMES 1399 Query: 6297 VKHNQENISSVLYKENVGKATATPV--TPEMQRVKRNQENISSVLYK----ENLGKATPT 6350 K E IS Y++ T V +P++ K + + + +Y+ E+L + T Sbjct: 1400 AKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLI 1459 Query: 6351 PFTPEMERVKRNQENFSSVLYKENMRKATPTPVTPEMER-----AKRNQENISSVLYSDS 6405 P P+ R + N + S +Y+ + + ++ A+ ++E S Y ++ Sbjct: 1460 PDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEA 1519 Query: 6406 FRKQIQGKAAY--VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKK 6463 F + + Y V D P M+ R S +Y +DF K + F P + K+ Sbjct: 1520 FLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKR 1579 Query: 6464 NMQDFSDINYRGIQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSL 6523 + Q SD++YR + Q D +Q GLR + D D +R + Sbjct: 1580 SQQLASDVHYR------QPLPQPTCDPEQ---LGLRHAQKAHQLQSDVKYKSDLNLTRGV 1630 Query: 6524 -----HMINVQAQRRSREQSRSASALSISGGEEKSEHSEAPDH 6561 V+ RR+ E + +A L + G +E EA DH Sbjct: 1631 GWTPPGSYKVEMARRAAELA-NARGLGLQGAYRGAEAVEAGDH 1672 Score = 315 bits (808), Expect = 7e-85 Identities = 373/1541 (24%), Positives = 651/1541 (42%), Gaps = 193/1541 (12%) Query: 4844 YKDDLNWLKGIGCY-VWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQA 4902 Y +D +G G + TP AK A L ++YK + + + V DTP +++ Sbjct: 157 YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRS 216 Query: 4903 VKSGKQL-SDAVYHYDYVHSVRGKVA-PTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTG 4960 K+G QL SD Y DY RGK + P T A A +L S Y + G Sbjct: 217 -KAGAQLQSDVRYTEDYEQQ-RGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRG 274 Query: 4961 YRLPGDTPHFKHIKDTRYMSSYFK-YKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSER 5019 + G + I Y + Y E YE + G + + ++ + + S+ Sbjct: 275 --MAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDI 332 Query: 5020 LYRELYHKLKDKIH----TTPDTPEIRQVKKTQEAVSELIYKSDFFK-MQGHMISLPYTP 5074 YR+ ++K+K H D ++Q + + VSE YK ++ M+G + Sbjct: 333 KYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDR 392 Query: 5075 QVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMR 5134 + +H VG + S++ YK D + D+V + L +Y K ++ Sbjct: 393 RTLHAMKVGSLASNVAYKADYK------------HDIVDYNYPATLTPSYQTAMKLVPLK 440 Query: 5135 D----------KYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRA 5184 D KY V DTP+ + + LS + YRA +K K +T D P L++A Sbjct: 441 DANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKA 500 Query: 5185 KRGQKLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYT 5243 K KL S+ Y E K + +L AK ++ S KYK +YEK K K Sbjct: 501 KTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAM 560 Query: 5244 PVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKE 5303 D+ +L + A + S++ YK+ F+++K ++H D ++I + +K S + Y++ Sbjct: 561 GTADSRLLHSLQIAKMS-SEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRK 619 Query: 5304 NYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNK 5363 +L + +P+ + + S+++YK DL W+KG+G + + A+K Sbjct: 620 ----KLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAG 675 Query: 5364 TLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDE 5423 L S+ Y++ + K F V DS H K + +L + Y+A EQ +Y + DE Sbjct: 676 QLVSEKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 733 Query: 5424 PRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNK 5482 P L A+ +S+ Y+ ++E K K F +D+ L S++ YK +Y + Sbjct: 734 PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYER 793 Query: 5483 AKPR--GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYK 5540 ++ + G + + H ++ S+L+YK+ ++ KS C + D VH+ A+ A Sbjct: 794 SRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQH 853 Query: 5541 VNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDK 5600 + T++ YK + H+ P A K+ QSD +Y+ D +++KG T Sbjct: 854 LATDVGYKTA----EHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSL 909 Query: 5601 NTVLALRNTLIESDLKYKE----------------------------KHVKERGTC---H 5629 N A + + S+ KY++ + +E+G H Sbjct: 910 NVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH 969 Query: 5630 AVP--DTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT 5687 P D P++LLAK + +SE +YK+ K L G Y + K + +SD Sbjct: 970 YTPTADLPEVLLAKLNAMNISETRYKESWSK-LRDGGYKLRLDALPFQAAKASGEIISDY 1028 Query: 5688 NYKKKFVKEKGKSNYSIMLEPP-EVKHAMEVAKKQSDVAYRKD---AKENLH-------- 5735 YK+ F K KG+ S LE + H++ QSDV Y+K +K H Sbjct: 1029 KYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAAL 1088 Query: 5736 ---------------------YTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSM 5774 YT++A+ + A +A K SE YR+ + Sbjct: 1089 VHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVI 1148 Query: 5775 LGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKA 5834 G +IE KKA++L S+ KYR++ K P K +N + +E YKA Sbjct: 1149 PGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHA----KFSNQITNERLYKA 1204 Query: 5835 ---DLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYE--KSKGHYHTIPDNLEQLH 5889 D + + + E + N + L+ + +YK+ + +++G+ TI + L Sbjct: 1205 AGEDARHEYTMTLGLPE--FIRAKTNAANLSDA-RYKESWRNLRAQGYKLTI-EALPFQA 1260 Query: 5890 LKEATELQSIVKYKEKYEKERGK---PMLDFETPTYITAKESQQMQSGKEYRKDYEESIK 5946 + + ++ S Y+ + KERGK P + P + Q+QS +YR+ S Sbjct: 1261 ARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQA 1320 Query: 5947 GRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQIL 6006 +L V L+H K A +AS+ +YR + T + + M AK A + Sbjct: 1321 QFHLPMDMVH--LVHAKNAQALASDHDYRTQYHK------FTALPEDLKMAWAKKAHALQ 1372 Query: 6007 NEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDT 6066 +E YK DL + +G+ +A +P A+ A ++ S+ KY++ + K FT+VVD+ Sbjct: 1373 SELRYKSDL---IGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIK--FTTVVDS 1427 Query: 6067 PEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNS 6126 P+++HA+ +++ Y+ +S+ Y + D P+ R R N + S Y+ + + Sbjct: 1428 PDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQT 1487 Query: 6127 KG----------KITVVQDTPEI---LRVKE-------------------NQKNFSSV-- 6152 + + + EI R KE K+F +V Sbjct: 1488 RAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGR 1547 Query: 6153 -----LYKEDVSPGTAIGKT----PEMMRVKQTQDHISSVKYKEAIGQGTPIPDLPEVKR 6203 YK+D + + + P +++ K++Q S V Y++ + Q T P+ ++ Sbjct: 1548 LQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRH 1607 Query: 6204 VKETQKHISSVMYKENL----GTGIPTTVTPEIERVKRNQE 6240 ++ + S V YK +L G G + ++E +R E Sbjct: 1608 AQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAE 1648 >gi|5453758 nebulette sarcomeric isoform [Homo sapiens] Length = 1014 Score = 631 bits (1628), Expect = e-180 Identities = 352/792 (44%), Positives = 499/792 (63%), Gaps = 17/792 (2%) Query: 5596 VTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDH 5655 V +D + LA + T + SD++YKE+ K + C V D+P + K + +SE KYK Sbjct: 33 VIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGT 92 Query: 5656 VKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAM 5715 +K L+ Y +P T D+V EVT+ S+ YK+K KG S+Y+ M EPPEVKHAM Sbjct: 93 IKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAM 152 Query: 5716 EVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSML 5775 EV K QS+++YRKD ++ Y+ DRPDIK ATQ +K S EY+ K + + +++ Sbjct: 153 EVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYK-KGQGIMNKEPAVI 211 Query: 5776 GRPDIEMAKKAAKLSSQVKYRENFDKE-KGKTPKYNPKDSQLYKVMKDANNLASEVKYKA 5834 GRPD E A +A+KLSSQ+KY+E FD E K K YNP +S ++ + A LAS VKYK Sbjct: 212 GRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKK 271 Query: 5835 DLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEAT 5894 D++ +H PV+D+ L ++HVL S++ S +YKK +E++KG YH D +E LH K Sbjct: 272 DIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNA 331 Query: 5895 ELQSIVKYKEKYEKERGKPMLDF-ETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGL 5953 LQS VKYKE+YEK +GKPML+F ETP+Y +KE+Q+MQS K Y++D+E+ IKGR+ L Sbjct: 332 VLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDL 391 Query: 5954 EVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKR 6013 + TP LHVKY T + EKEY+KDLE I+GKG+ + D+ RAK A+++ +EKEYK+ Sbjct: 392 DKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKK 451 Query: 6014 DLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEME-KANFTSV-VDTPEIIH 6071 DLE +KG+G+ A +T + A+ A +IAS+ YK+ E E K V DT ++ Sbjct: 452 DLESIIKGKGMQA-GTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQR 510 Query: 6072 AQQVKNLSSQKKYKEDAEKSMSY--YETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGK 6129 A++ ++SQK+YK+D E + + +D P+I R + + +S +Y+ + + Sbjct: 511 AKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSN 570 Query: 6130 ITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMMRVKQTQDHISSVKYKEAI 6189 + + DTPEI R+K Q+N S+V YK++V GTA+ +PE+ RVK+ Q +ISSVKYKE I Sbjct: 571 YSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEI 630 Query: 6190 GQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTPEIERVKRNQENFSSVLYKE 6249 T I D PE+KRVKE QK+IS++ YKE P ++TPEIERV+RNQE S+V YK Sbjct: 631 KHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKG 690 Query: 6250 NLGKGIPTPITPEMERVKRNQENFSSVLYKENMGKGTPLAVTPEMERVKHNQENISSVLY 6309 L +G PE++R K NQ+N S+V Y+ +G+ T L+VTPEMERVK NQENISSV Y Sbjct: 691 ELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKY 750 Query: 6310 ----KENVGKATATPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEM-----ERVK 6360 K+ G+ + TP M+ VK Q +IS V Y E+ K FTP + ERV+ Sbjct: 751 TQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVR 810 Query: 6361 RNQENFSSVLYK 6372 +N + S YK Sbjct: 811 KNTQVVSDAAYK 822 Score = 561 bits (1447), Expect = e-159 Identities = 373/1057 (35%), Positives = 575/1057 (54%), Gaps = 110/1057 (10%) Query: 5639 LAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKG 5698 LA+ + L+S+ +YK+ KK + ++ T ++ HVK + +S+ YK + Sbjct: 41 LARKCTELISDIRYKEEFKKSKDKCTFVT--DSPMLNHVKNIGAFISEAKYKGTIKADLS 98 Query: 5699 KSNYSIMLEPPEVKHAMEVAKKQSDVAYRKD---AKENLHYTTVADRPDIKKATQAAKQA 5755 S Y M + A EV + QS+VAY++ AK Y + + P++K A + K Sbjct: 99 NSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQ 158 Query: 5756 SEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQ 5815 S + YR + ++ L RPDI+MA + +K+ S +Y++ Sbjct: 159 SNISYRKDVQDTHTYSAE-LDRPDIKMATQISKIISNAEYKKG----------------- 200 Query: 5816 LYKVMKDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYE--- 5872 + N V + D + H + S+L+S +YK+K++ Sbjct: 201 -----QGIMNKEPAVIGRPDFE----------------HAVEASKLSSQIKYKEKFDNEM 239 Query: 5873 KSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYIT-AKESQQM 5931 K K H++ ++ + A L S VKYK+ + P+ D ++ ++ +M Sbjct: 240 KDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHD-PVSDLPNLLFLDHVLKASKM 298 Query: 5932 QSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEME 5991 SG+EY+K +EE+ KG + L H A + S+ +Y+++ E++ +GK + E Sbjct: 299 LSGREYKKLFEEN-KGMYHFDADAVEHLHHKGNAV-LQSQVKYKEEYEKN-KGKPMLEFV 355 Query: 5992 DTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQ 6051 +TP +K A ++ +EK YK D E E+KGR + ++TP+F+ + T++ + +YK+ Sbjct: 356 ETPSYQASKEAQKMQSEKVYKEDFEKEIKGRS-SLDLDKTPEFLHVKYITNLLREKEYKK 414 Query: 6052 SAEMEKANFTSVVDTP--EIIHAQQVKNLSSQKKYKEDAEKSMSY--YETVLDTPEIQRV 6107 E E +++ +I A++ ++S+K+YK+D E + + DT E+Q Sbjct: 415 DLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHA 474 Query: 6108 RENQKNFSLLQYQCDLKNS-KGK-ITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIG 6165 ++ + S Y+ DL+ KGK + V DT ++ R K+ + S YK+D+ Sbjct: 475 KKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLE------ 528 Query: 6166 KTPEMMRVKQTQDHISSVKYKEAIGQGTPIP-DLPEVKRVKETQKHISSVMYKEN----L 6220 E G+G + D+P++ R K T + S YK+ L Sbjct: 529 --------------------NEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKML 568 Query: 6221 GTGIPTTVTPEIERVKRNQENFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKE 6280 TPEI+R+K Q+N S+V YK+ +G G +PE+ERVK+NQ+N SSV YKE Sbjct: 569 SNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKE 628 Query: 6281 NMGKGTPLAVTPEMERVKHNQENISSVLYKENVGKATATPVTPEMQRVKRNQENISSVLY 6340 + T ++ PE++RVK NQ+NIS++ YKE KAT +TPE++RV+RNQE +S+V Y Sbjct: 629 EIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKY 688 Query: 6341 KENLGKATPTPFTPEMERVKRNQENFSSVLYKENMRKATPTPVTPEMERAKRNQENISSV 6400 K L + T PE++R K NQ+N S+V Y+ + +AT VTPEMER K+NQENISSV Sbjct: 689 KGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSV 748 Query: 6401 LYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFEKHKGC-FTPVVTDPITE 6459 Y+ KQ++G+ + +LDTP MR V+E Q HIS VKYHEDFEK KG FTPVV DP+TE Sbjct: 749 KYTQD-HKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTE 807 Query: 6460 RVKKNMQDFSDINYRGIQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQ 6519 RV+KN Q SD Y+G+ +VEM+++ I L+VWRT+PGS+FD DP EDNIQ Sbjct: 808 RVRKNTQVVSDAAYKGVHPHIVEMDRRPG-----IIVDLKVWRTDPGSIFDLDPLEDNIQ 862 Query: 6520 SRSLHMINVQAQ--RRSREQSRSASALSISGGEEKSEHSEAPDH-----HLSTYSDGGVF 6572 SRSLHM++ +A RR +S S+S G+++SE SE ++ SD G Sbjct: 863 SRSLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAP 922 Query: 6573 AVSTAYKHAKTTELPQQRSSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFK 6632 + AY+ + + +SV++ + S+ P+ + +RAMYDY A D DEVSF+ Sbjct: 923 VLPGAYQQSHSQGYGYMHQTSVSSMR----SMQHSPNL--RTYRAMYDYSAQDEDEVSFR 976 Query: 6633 DGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 DGD I+NVQ ID+GWMYGTVQRTGRTGMLPANY+E + Sbjct: 977 DGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 1013 Score = 286 bits (733), Expect = 4e-76 Identities = 250/885 (28%), Positives = 414/885 (46%), Gaps = 91/885 (10%) Query: 5389 PINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKS 5448 P+ K T+ EK + E+ + Y V+++ LA+ + IS I+Y++ ++KS Sbjct: 4 PVFEDIKDETE--EEKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKS 61 Query: 5449 KDKFTSIVDTPEHLRTTKVNKQISDILY----KLEYNKAKPRGYTTIHDTPMLLHVRKVK 5504 KDK T + D+P + IS+ Y K + + + + D+ V +++ Sbjct: 62 KDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQ 121 Query: 5505 DEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDR 5564 EV+ K K + S+ + +K A + K +N+ Y+K + + DR Sbjct: 122 SEVA-YKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDR 179 Query: 5565 PDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEK---H 5621 PD A + S S+ EYK + + + +V + A+ + + S +KYKEK Sbjct: 180 PDIKMATQISKIISNAEYKKGQGIMNK-EPAVIGRPDFEHAVEASKLSSQIKYKEKFDNE 238 Query: 5622 VKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVT 5681 +K++ + ++ + + L S KYK ++ + LP HV + + Sbjct: 239 MKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQN--MHDPVSDLPNLLFLDHVLKAS 296 Query: 5682 KHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVAD 5741 K +S YKK F + KG ++ DA E+LH+ Sbjct: 297 KMLSGREYKKLFEENKGMYHFD------------------------ADAVEHLHH----- 327 Query: 5742 RPDIKKATQAAKQASEVEYRAKHRK-EGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFD 5800 A S+V+Y+ ++ K +G L + P + +K+A K+ S+ Y+E+F+ Sbjct: 328 -------KGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFE 380 Query: 5801 KE-KGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLKK--LHKPVTDMKESLIMNHVLN 5857 KE KG++ K + V K NL E +YK DL+ K + E L + Sbjct: 381 KEIKGRSSLDLDKTPEFLHV-KYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKR 439 Query: 5858 TSQLASSYQYKKKYE---KSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKE-RGKP 5913 S++AS +YKK E K KG D LE H K+A E+ S YK E E +GK Sbjct: 440 ASEMASEKEYKKDLESIIKGKG-MQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKG 498 Query: 5914 M-LDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEK 5972 M + +T AK++ +M S K+Y+KD E IKG+ + P +L K ++I S++ Sbjct: 499 MQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQR 558 Query: 5973 EYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETP 6032 +Y+ + E+ + + + DTP++ R K Q ++ YK+++ G ++P Sbjct: 559 KYKDEAEKML--SNYSTIADTPEIQRIKTTQQNISAVFYKKEV-------GAGTAVKDSP 609 Query: 6033 DFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSM 6092 + R + S +KYK+ E + T++ D PE+ ++ + S +YKE K+ Sbjct: 610 EIERVKKNQQNISSVKYKE----EIKHATAISDPPELKRVKENQKNISNLQYKEQNYKA- 664 Query: 6093 SYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSV 6152 V TPEI+RVR NQ+ S ++Y+ +L+ T + D PE+ R KENQKN S+V Sbjct: 665 ---TPVSMTPEIERVRRNQEQLSAVKYKGELQRG----TAISDPPELKRAKENQKNISNV 717 Query: 6153 LYKEDVSPGTAIGKTPEMMRVKQTQDHISSVKY----KEAIGQGTPIPDLPEVKRVKETQ 6208 Y+ + T + TPEM RVK+ Q++ISSVKY K+ G+ + I D P ++ VKE Q Sbjct: 718 YYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQ 777 Query: 6209 KHISSVMYKENL----GTGI-PTTVTPEIERVKRNQENFSSVLYK 6248 HIS V Y E+ G G P P ERV++N + S YK Sbjct: 778 NHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822 Score = 207 bits (528), Expect = 2e-52 Identities = 215/847 (25%), Positives = 385/847 (45%), Gaps = 66/847 (7%) Query: 486 DQCKDHTY--KVHPDKTKFTQVTDSPVLLQAQVN-----SKQLSDLNYKAKHESEKFKCH 538 + KD T K+ ++ + QV PV+ + ++ +SD+ YK + + K KC Sbjct: 7 EDIKDETEEEKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCT 66 Query: 539 IPPDTPAFIQHKVNAYNLSDNLYK----QDWEKSKAKKFDIKVDAIPLLAAKANTKNTSD 594 D+P K +S+ YK D S K+ +D++ A T+ S+ Sbjct: 67 FVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSV---FAGEVTQLQSE 123 Query: 595 VMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPK 654 V YK+ ++ KG + + P++ H+++V K+QS+ Y+++ + T S + P Sbjct: 124 VAYKQKHDAAKG-FSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAEL-DRPD 181 Query: 655 YQLDTQL-KNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEED- 712 ++ TQ+ K S A YK + ++ + P H ++ + +S YK +++ + Sbjct: 182 IKMATQISKIISNAEYKK--GQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEM 239 Query: 713 KGKCYFPQTITQEYEAIKKLDQCKDHTYKVHPD-KTKFTAVTDSPVLL---QAQLNTKQL 768 K K + + +L K D + V+D P LL +K L Sbjct: 240 KDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKML 299 Query: 769 SDLNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIP 828 S YK E K H ADA + + H+ NA S YK+++EK+K K V+ Sbjct: 300 SGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPS 359 Query: 829 LLAAKANTKNTSDVMYKKDYEKS-KGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYE 887 A+K K S+ +YK+D+EK KG+ +L ++ P+ LH ++EY+KD E Sbjct: 360 YQASKEAQKMQSEKVYKEDFEKEIKGR--SSLDLDKTPEFLHVKYITNLLREKEYKKDLE 417 Query: 888 ---KSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILHS------YSYPPDSINVDLAKK 938 K K + ++L + +AK++ +AS+ +YK L S D++ + AKK Sbjct: 418 NEIKGKGM-ELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKK 476 Query: 939 AYALQSDVEYKADYNSWMKGCGW-VPFGSLEMEKAKRASDILNEKKYRQH-PDTLKFTSI 996 A + S+ +YK D + +KG G V +L++++AK+AS++ ++K+Y++ + +K + Sbjct: 477 AAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGM 536 Query: 997 E---DAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYK 1053 + D P +++K S YK + E+++ Y+ D P+ + K NIS YK Sbjct: 537 QVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYK 596 Query: 1054 ADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVH 1113 ++ G ++ D+ I K +Q S V+YK++ + A ++ D P+L Sbjct: 597 KEV----GAGTAVK-DSPEIERVKKNQQNISSVKYKEEIKHA-------TAISDPPELKR 644 Query: 1114 YMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPD 1173 K S+ +YK+ K TP + ++ Q+ +S V YK L T + D Sbjct: 645 VKENQKNISNLQYKEQNYKATPVSMTP----EIERVRRNQEQLSAVKYKGELQRGTAISD 700 Query: 1174 AMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPD 1233 +L+ +K Q NVY + P ++E+VKK + ++ KY Q Sbjct: 701 PPELKRAKE-NQKNISNVYYRGQLGRATTLSVTP----EMERVKKNQENISSVKYTQDHK 755 Query: 1234 TLKF--TSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHK-YTMSPDLPQFLQAKCNAYN 1290 +K + I+D+P M K+ +S + Y E K + +T D P + + N Sbjct: 756 QMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV 815 Query: 1291 ISDVCYK 1297 +SD YK Sbjct: 816 VSDAAYK 822 Score = 203 bits (517), Expect = 4e-51 Identities = 219/895 (24%), Positives = 374/895 (41%), Gaps = 129/895 (14%) Query: 4400 FRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILY 4459 ++ V++ + LA+ + SD++YKE F K+K K TF D+P ++H K++G S Y Sbjct: 30 YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKY 89 Query: 4460 KGAWEGTKAYG-YTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGV 4518 KG + + Y I V A + SE+ YK+ ++ KG + + E P V Sbjct: 90 KGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG-FSDYAHMKEPPEV 148 Query: 4519 VHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSL 4578 H ++ K +S ++YRK +DT H +++ Sbjct: 149 KHAMEVNKHQSNISYRKDVQDT--------------------------------HTYSAE 176 Query: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY-----VWDTPQILHAKKSYDLQSQLQ 4633 L+ P++ +I+S+ YK KG G V P HA ++ L SQ++ Sbjct: 177 LDRPDIKMATQISKIISNAEYK------KGQGIMNKEPAVIGRPDFEHAVEASKLSSQIK 230 Query: 4634 YTA----AGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDY 4689 Y K+ +YN + + + + AS VKYK++ + D + + + Sbjct: 231 YKEKFDNEMKDKKHHYNPLESASFRQNQLAATL-ASNVKYKKDIQNMHDPVSDLPNLLFL 289 Query: 4690 DRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKA 4749 D + S YK+ ++ K Y + + H K L S +KY+EEYEK K Sbjct: 290 DHVLKASKMLSGREYKKLFEENKG-MYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKG 348 Query: 4750 LYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKN-KMKIHIVPDMV-EMVTAKDSQKK 4807 L + P+ K+ +++Y+ +EK K + + D E + K Sbjct: 349 KPML--EFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNL 406 Query: 4808 VSEIDYRLRLHEWICHPDLQVNDHV------RKVTDQISDIVYKDDL-NWLKGIGCYV-W 4859 + E +Y+ L I +++N V ++ ++ S+ YK DL + +KG G Sbjct: 407 LREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGT 466 Query: 4860 DTPEILHAKHAYDLRDDIKYKAHMLKTR---NDYKLVTDTPVYVQAVKSGKQLSDAVYHY 4916 DT E+ HAK A ++ + YK L+T ++ TDT +A K+ + S Y Sbjct: 467 DTLEMQHAKKAAEIASEKDYKRD-LETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKK 525 Query: 4917 DYVHSVRGKVAPTTKTV-DLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKD 4975 D + ++GK + + D+ RA ++ S YK + + Y DTP + IK Sbjct: 526 DLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKT 585 Query: 4976 TRYMSSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVN--NVTSERLYRELYHKLKDKIH 5033 T+ S YK K G KD P + + N N++S + E+ H Sbjct: 586 TQQNISAVFYK------KEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHAT----- 634 Query: 5034 TTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKE 5093 D PE+++VK+ Q+ +S L YK +K + TP++ R + S +KYK Sbjct: 635 AISDPPELKRVKENQKNISNLQYKEQNYK----ATPVSMTPEIERVRRNQEQLSAVKYKG 690 Query: 5094 DLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELK 5153 +LQ G + D P++ R++ +K SN Y R + + TPE +V++ + Sbjct: 691 ELQ----RGTAISDPPELKRAKENQKNISNVYY----RGQLGRATTLSVTPEMERVKKNQ 742 Query: 5154 THLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQT 5213 ++S + Y K+ K + + DTP + K Q Sbjct: 743 ENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQ------------------------- 777 Query: 5214 TALKHAKDVKDMVSEKKYKIQYEKMKDK-YTPVPDTPILIRAKRAYWNASDLRYK 5267 + +S KY +EK K + +TPV D P+ R ++ SD YK Sbjct: 778 ----------NHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822 Score = 201 bits (510), Expect = 3e-50 Identities = 224/859 (26%), Positives = 372/859 (43%), Gaps = 108/859 (12%) Query: 602 EKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQL 661 E+N+ + + +D M + K + SD YKE ++K+K K ++P + Sbjct: 21 EENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNI 80 Query: 662 KNF-SEARYKDLYVKDVLGHYVGSMEDPYHT-HCMKVAAQNSDKSYKAEYEEDKGKCYFP 719 F SEA+YK D+ M + +V S+ +YK +++ KG + Sbjct: 81 GAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG--FSD 138 Query: 720 QTITQEYEAIKKLDQCKDHTYKVH-----PDKTKFTAVTDSPVLLQAQLNTKQLSDLNYK 774 +E +K + H + D ++A D P + A +K +S+ YK Sbjct: 139 YAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYK 198 Query: 775 AKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNV-YKQDWEKSKAKKFDIKVDAIPLLAAK 833 K +G K P F +H V A LS + YK+ ++ K K PL +A Sbjct: 199 -KGQGIMNKEPAVIGRPDF-EHAVEASKLSSQIKYKEKFDNEMKDK---KHHYNPLESAS 253 Query: 834 ANTKN-----TSDVMYKKDYEKSKGKMIGALSINDDPKML---HSLKTAKNQSDREYRKD 885 S+V YKKD + ++D P +L H LK +K S REY+K Sbjct: 254 FRQNQLAATLASNVKYKKDIQNMHDP------VSDLPNLLFLDHVLKASKMLSGREYKKL 307 Query: 886 YEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILHSYSYPP-----DSINVDLAKKAY 940 +E++K +Y D ++ K + + S V YK P ++ + +K+A Sbjct: 308 FEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQ 367 Query: 941 ALQSDVEYKADYNSWMKGCGWVPFGSLEMEKA------KRASDILNEKKYRQHPDTLKFT 994 +QS+ YK D+ +KG SL+++K K +++L EK+Y++ + Sbjct: 368 KMQSEKVYKEDFEKEIKGRS-----SLDLDKTPEFLHVKYITNLLREKEYKKDLEN---- 418 Query: 995 SIEDAPITVQSKINQAQR--------SDIAYKAKGEEIIHKYNLPP--DLPQFIQAKVNA 1044 I+ + + S++ QR S+ YK E II + D + AK A Sbjct: 419 EIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAA 478 Query: 1045 YNISENMYKADLK-DLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYE-KAKGKMVGF 1102 SE YK DL+ ++ KG + TD + ++ AK A + AS QYKKD E + KGK G Sbjct: 479 EIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGK--GM 536 Query: 1103 QSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHD----------MFNVVAA--- 1149 Q D P ++ ++I S R+YK + EK S Y+T D N+ A Sbjct: 537 QVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYK 596 Query: 1150 ------------------KKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNV 1191 KK Q +S+V YK + H T + D +L+ K + S+ Sbjct: 597 KEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQ 656 Query: 1192 YKEDYNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQ 1251 YKE N + P ++E+V++ + L+ KY+ + + T+I D P + +AK+ Sbjct: 657 YKEQ-NYKATPVSMTP----EIERVRRNQEQLSAVKYKG--ELQRGTAISDPPELKRAKE 709 Query: 1252 NTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVL 1311 N K +S++ Y+ + + T P+ + K N NIS V Y +D + + + +L Sbjct: 710 NQKNISNVYYRGQ----LGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLIL 765 Query: 1312 GDAIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYK 1371 D + K ++N S KY E +EK+KG+ GF + DDP ++ SD YK Sbjct: 766 -DTPAMRHVKEAQNHISMVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 822 Query: 1372 KNYENTKTSYHTPGDMVSI 1390 + + PG +V + Sbjct: 823 GVHPHIVEMDRRPGIIVDL 841 Score = 199 bits (505), Expect = 1e-49 Identities = 209/819 (25%), Positives = 368/819 (44%), Gaps = 62/819 (7%) Query: 89 SQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYR--MDGDVAKT 146 ++K +L S +YKE+F+K+K + TD+P L +K + +SE KY+ + D++ + Sbjct: 42 ARKCTELISDIRYKEEFKKSKDK-CTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNS 100 Query: 147 ICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTK--DKYLLPPDAPELVQAVKNTAMFSK 204 + D A +V+Q S+V YKQ + K Y + PE+ A++ S Sbjct: 101 LYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSN 160 Query: 205 KLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEF 264 Y +D + D + D P+++ Q K +S+ YKKG + + PD E Sbjct: 161 ISYRKDVQ-DTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKE-PAVIGRPDFEH 218 Query: 265 AKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMN---ADNISTRKYQEDFENMKD 321 A + + S+ KYKE ++N++K K E A+ R N A S KY++D +NM D Sbjct: 219 AVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHD 278 Query: 322 QIYFMQTETPEYKMNK---KAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAA 378 + ++ P KA S +YK+ +E+NKG ++ + L Sbjct: 279 PV----SDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDA------DAVEHLHHK 328 Query: 379 GDAL--SDKLYKENYEKTKAK-SINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGH-Y 434 G+A+ S YKE YEK K K + + ETP ++ Q S+K YK+ + K+I G Sbjct: 329 GNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSS 388 Query: 435 VGSFEDPYHSHCMKVTAQNSDKNYKAEYE-EDRGKGFFPQTITQEYEAIKKL-DQCKDHT 492 + + P H +T +K YK + E E +GKG + + + K+ + + Sbjct: 389 LDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKE 448 Query: 493 YKVHPD---KTKFTQV-TDSPVLLQAQVNSKQLSDLNYKAKHESE-KFK-CHIPPDTPAF 546 YK + K K Q TD+ + A+ ++ S+ +YK E+E K K + DT Sbjct: 449 YKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDV 508 Query: 547 IQHKVNAYNLSDNLYKQDWEKS-KAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNK 605 + K + S YK+D E K K + +D +L A K TS++ ++ Y+ Sbjct: 509 QRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRA----KRTSEIYSQRKYKDEA 564 Query: 606 GKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQ-LDTQLKNF 664 KM+ S D + +K + ++ Y+K ++P+ + + +N Sbjct: 565 EKMLSNYSTIADTPEIQRIKTTQQNISAVF---YKKEVGAGTAVKDSPEIERVKKNQQNI 621 Query: 665 SEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQ 724 S +Y K+ + H + P +K +N +Y+E K P ++T Sbjct: 622 SSVKY-----KEEIKHATAISDPPE----LKRVKENQKNISNLQYKEQNYKA-TPVSMTP 671 Query: 725 EYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKC 784 E E +++ +Q + K + + TA++D P L +A+ N K +S++ Y+ G+ + Sbjct: 672 EIERVRR-NQEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYR----GQLGRA 726 Query: 785 HIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMY 844 + P+ + + N N+S Y QD ++ K + + +D + K + S V Y Sbjct: 727 TTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKY 785 Query: 845 KKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYR 883 +D+EK+KG+ G + DDP K + SD Y+ Sbjct: 786 HEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 822 Score = 194 bits (492), Expect = 3e-48 Identities = 213/902 (23%), Positives = 389/902 (43%), Gaps = 99/902 (10%) Query: 1461 KKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDP 1520 +K G+ NE D V + V + + M LA+ T+ +SD+ YK E +K K K T Sbjct: 16 EKIGEEENEE------DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVT 69 Query: 1521 ELPQFIQAKVNALNMSDAHYKADWKKTIAKG-YDLRPDAIPIVAAKSSRNIASDCKYKEA 1579 + P K +S+A YK K ++ Y P I V A + S+ YK+ Sbjct: 70 DSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQK 129 Query: 1580 YEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKK 1639 ++ AKG + +++ P++ H M V K QS+ Y+K + + T Y LD + A + Sbjct: 130 HDAAKGFS-DYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDIKMATQ 187 Query: 1640 SQEVATNANYRQSYHHYTLLPDAL---NVEHSRNAMQIQSDNLYKSDFTNWMKG--IGWV 1694 ++ +NA Y++ P + + EH+ A ++ S YK F N MK + Sbjct: 188 ISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYN 247 Query: 1695 PIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYA----MDTMEQALNKSNKLNMDKRLYT 1750 P+ES + + A + S KY++ + + + + ++ L S L+ R Y Sbjct: 248 PLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLS--GREYK 305 Query: 1751 EKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARA 1810 + + ++K H D + L + N + S YK +E+ K K + + +A++ Sbjct: 306 KLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKE 365 Query: 1811 SRDIASDYKYKKAYE-QAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEK--SKT 1867 ++ + S+ YK+ +E + KG+ L+ P+ +H + + ++EYKK E Sbjct: 366 AQKMQSEKVYKEDFEKEIKGR--SSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGK 423 Query: 1868 SFHTPVDMLSVVAAKKSQEVATNANYR----NVIHTYNML--PDAMSFELAKNMMQIQSD 1921 ++L + AK++ E+A+ Y+ ++I M D + + AK +I S+ Sbjct: 424 GMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASE 483 Query: 1922 NQYKADYADFMKGIGW-LPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVL 1980 YK D +KG G + +L+ ++ KKA E+ S+K+Y++ D N + Sbjct: 484 KDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKK-----------DLENEIK 532 Query: 1981 AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKK--K 2038 + + + DIP I+ AK + S + YK +E++K Sbjct: 533 GKG--------------------MQVSMDIPDILRAKRTSEIYSQRKYK---DEAEKMLS 569 Query: 2039 GYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQS 2098 Y D I+ K ++ S YK E G G V +D P++ + + S Sbjct: 570 NYSTIADTPEIQRIKTTQQNISAVFYK--KEVGAGTAV-----KDSPEIERVKKNQQNIS 622 Query: 2099 DREYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRN 2158 +YK+ ++ T+ P ++ V K+ Q NI+N YK +K A + +T Sbjct: 623 SVKYKEEIKHA-TAISDPPELKRV---KENQKNISNLQYKEQNYK------ATPVSMTPE 672 Query: 2159 MNRIQSDNEYKQDYNEWYKG---LGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKK 2215 + R++ + E YKG G + + E+++AK+ + S+ YR Sbjct: 673 IERVRRNQEQLSAVK--YKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLS 730 Query: 2216 LTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLG 2275 +T M+ V K+N ++ YT D + K + ++ DTP + K+ Q S Y Sbjct: 731 VTPEMERV--KKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHED 788 Query: 2276 WEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSM 2335 +E+ +G+ VD + + + + SD YK G H + P +++ + Sbjct: 789 FEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK-------GVHPHIVEMDRRPGIIVDL 841 Query: 2336 NV 2337 V Sbjct: 842 KV 843 Score = 191 bits (485), Expect = 2e-47 Identities = 202/837 (24%), Positives = 358/837 (42%), Gaps = 92/837 (10%) Query: 5002 KDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFF 5061 +D+ R+ + S+ Y+E + K KDK D+P + VK +SE YK Sbjct: 35 EDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIK 94 Query: 5062 KMQGHMI--SLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLY--DTPDMVRSRHL 5117 + + +P T + V + S++ YK+ KGF + + + P++ + + Sbjct: 95 ADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEV 154 Query: 5118 RKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPD 5177 K SN Y + Y LD P+ + + T +S+++ A KK + I P Sbjct: 155 NKHQSNISYRKDVQDTHT-YSAELDRPDIK----MATQISKIISNAEYKKGQGIMNKEPA 209 Query: 5178 T---PDLLRAKRGQKLQSQYLYVEL---ATKERPHHHAGNQTTALKHAKDVKDMVSEKKY 5231 PD A KL SQ Y E K++ HH+ ++ + + + + S KY Sbjct: 210 VIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKY 269 Query: 5232 KIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRK 5291 K + M D + +P+ L +A S YK+ F++ KG YH DA++ ++H+ Sbjct: 270 KKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKG 329 Query: 5292 VTDDISKIKYKENYMSQLG-------------------------IWR------------- 5313 S++KYKE Y G +++ Sbjct: 330 NAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSL 389 Query: 5314 SIPDRPEHFHHRAVTDTVSDVKYKEDL-TWLKGIGC-YAYDTPDFTLAEKNKTLYSKYKY 5371 + PE H + +T+ + + +YK+DL +KG G + D A++ + S+ +Y Sbjct: 390 DLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEY 449 Query: 5372 KEVFER--TKSDFKYVADSPINRHFKYATQLMNEKKYRADYE-QRKDK-YHLVVDEPRHL 5427 K+ E + D+ +H K A ++ +EK Y+ D E + K K + D Sbjct: 450 KKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQ 509 Query: 5428 LAKTAGDQISQIKYRKNYEKS-KDKFTSI-VDTPEHLRTTKVNKQISDILYKLEYNKAKP 5485 AK A + SQ +Y+K+ E K K + +D P+ LR + ++ S YK E K Sbjct: 510 RAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKML- 568 Query: 5486 RGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNL 5545 Y+TI DTP + ++ + +S + YK + T D+ I+ K + +++ Sbjct: 569 SNYSTIADTPEIQRIKTTQQNISAVFYK----KEVGAGTAVKDSPEIERVKKNQQNISSV 624 Query: 5546 DYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLA 5605 YK++ + H D P+ + ++ S+ +YK + K +S+T + V Sbjct: 625 KYKEEIK----HATAISDPPELKRVKENQKNISNLQYK--EQNYKATPVSMTPEIERV-- 676 Query: 5606 LRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSY 5665 RN S +KYK + +RGT A+ D P++ AK +S Y+ + G Sbjct: 677 RRNQEQLSAVKYKGE--LQRGT--AISDPPELKRAKENQKNISNVYYRGQL------GRA 726 Query: 5666 TTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVA 5725 TTL T + VK+ +++S Y + + KG+ S++L+ P ++H E S V Sbjct: 727 TTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRP--SLILDTPAMRHVKEAQNHISMVK 784 Query: 5726 YRKDAK--ENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLGRPDI 5780 Y +D + + +T V D P ++ + + S+ Y+ H H + M RP I Sbjct: 785 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH----PHIVEMDRRPGI 837 Score = 189 bits (481), Expect = 6e-47 Identities = 214/845 (25%), Positives = 376/845 (44%), Gaps = 81/845 (9%) Query: 5220 KDVKDMVSEKKYKIQYEKMKDK--YTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKY 5277 +D+KD E+K + E +D+ Y PV + + A++ SD+RYKE F+K+K K Sbjct: 7 EDIKDETEEEKIG-EEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKC 65 Query: 5278 HTVKDALDIVYHRKVTDDISKIKYKENYMSQL--GIWRSIPDRPEHFHHRAVTDTVSDVK 5335 V D+ + + + + IS+ KYK + L +++ +P + VT S+V Sbjct: 66 TFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVA 125 Query: 5336 YKEDLTWLKGIGCYAY------------------------------------DTPDFTLA 5359 YK+ KG YA+ D PD +A Sbjct: 126 YKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMA 185 Query: 5360 EKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYE-QRKDKYH 5418 + + S +YK+ + + V P H A++L ++ KY+ ++ + KDK H Sbjct: 186 TQISKIISNAEYKK-GQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKH 244 Query: 5419 LV--VDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQISDILY 5476 ++ + A S +KY+K+ + D + + + K +K +S Y Sbjct: 245 HYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREY 304 Query: 5477 KLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIE-PDAVHIKAA 5535 K + + K Y D LH + S +KYKE Y++NK +E + +A+ Sbjct: 305 KKLFEENKGM-YHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQAS 363 Query: 5536 KDAYKVNTNLDYKKQYEAN-KAHWKWTPDR-PDFLQAAKSSLQQSDFEYKLDRE-FLKGC 5592 K+A K+ + YK+ +E K D+ P+FL + + EYK D E +KG Sbjct: 364 KEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGK 423 Query: 5593 KLSVTDDKNTV-LALRNTLIESDLKYK---EKHVKERGTCHAVPDTPQILLAKTVSNLVS 5648 + + + + A R + + S+ +YK E +K +G A DT ++ AK + + S Sbjct: 424 GMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKG-MQAGTDTLEMQHAKKAAEIAS 482 Query: 5649 ENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEP 5708 E YK ++ + +T D K+ ++ S YKK E + ++ Sbjct: 483 EKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDI 542 Query: 5709 PEVKHAMEVAKKQSDVAYRKDAKENL-HYTTVADRPDIKKATQAAKQASEVEYRAKHRKE 5767 P++ A ++ S Y+ +A++ L +Y+T+AD P+I++ + S V Y +KE Sbjct: 543 PDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFY----KKE 598 Query: 5768 GSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLA 5827 G ++ P+IE KK + S VKY+E K T +P +L +V ++ N+ Sbjct: 599 VGAGTAVKDSPEIERVKKNQQNISSVKYKEEI---KHATAISDP--PELKRVKENQKNI- 652 Query: 5828 SEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQ 5887 S ++YK K PV+ E + V + S+ +YK + ++ I D E Sbjct: 653 SNLQYKEQNYKA-TPVSMTPE---IERVRRNQEQLSAVKYKGELQRGT----AISDPPE- 703 Query: 5888 LHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEESIKG 5947 LK A E Q + Y + G+ TP K++Q+ S +Y +D+++ +KG Sbjct: 704 --LKRAKENQKNIS-NVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQ-MKG 759 Query: 5948 RNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILN 6007 R L+ TPA+ HVK A S +Y +D E++ +G+G T + D P R + TQ+++ Sbjct: 760 RPSLILD-TPAMRHVKEAQNHISMVKYHEDFEKT-KGRGFTPVVDDPVTERVRKNTQVVS 817 Query: 6008 EKEYK 6012 + YK Sbjct: 818 DAAYK 822 Score = 176 bits (447), Expect = 5e-43 Identities = 209/828 (25%), Positives = 352/828 (42%), Gaps = 89/828 (10%) Query: 4156 FTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYT-LTETPLLHTAQEAARILDQYLY 4214 + PV + + A++ E++ DI+Y++++ +K K T +T++P+L+ + + + Y Sbjct: 30 YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKY 89 Query: 4215 KEGWERQKATG-YILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKL 4273 K + + Y P + V A +QSE+ YK +H KG + M++ P++ Sbjct: 90 KGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG-FSDYAHMKEPPEV 148 Query: 4274 VWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYR------NYL 4327 + Q+ Y++D T + D + A Q ++S+ +Y+ N Sbjct: 149 KHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDIKMATQISKIISNAEYKKGQGIMNKE 207 Query: 4328 HQWMCHPDQNDVIQARK-----------------------------------AYDLQSDN 4352 + PD ++A K A L S+ Sbjct: 208 PAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNV 267 Query: 4353 VYRADLEWLRG-IGWIP-LDSVDHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIV 4410 Y+ D++ + + +P L +DHV K +M+S +YKK EN + D E + Sbjct: 268 KYKKDIQNMHDPVSDLPNLLFLDHV--LKASKMLSGREYKKLFEENKGMYHFDADAVEHL 325 Query: 4411 LAKINSVNQSDVKYKETFNKAKGKYTFS-PDTPHISHSKDMGKLYSTILYKGAWEGTKAY 4469 K N+V QS VKYKE + K KGK +TP SK+ K+ S +YK +E Sbjct: 326 HHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKG 385 Query: 4470 GYTLDERYIP-IVGAKHADLVNSELKYKETYE---KQKGHYLAGKVIGEFPGVVHCLDFQ 4525 +LD P + K+ + E +YK+ E K KG L +V+ + Sbjct: 386 RSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLD----IQRAKRAS 441 Query: 4526 KMRSALNYRKHYEDT--KANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTS------ 4577 +M S Y+K E + D + AK+ I S+ +Y+ Sbjct: 442 EMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQV 501 Query: 4578 LLEEPNVIRVRNAQEILSDNVYKDDL-NWLKGIGCYV-WDTPQILHAKKSYDLQSQLQYT 4635 + +V R + A E+ S YK DL N +KG G V D P IL AK++ ++ SQ +Y Sbjct: 502 STDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYK 561 Query: 4636 AAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNL 4695 ++ L NY+ + DTP + N S V YK+ T V ++ + +R + Sbjct: 562 DEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEV----GAGTAVKDSPEIERVKKN 617 Query: 4696 KNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPR 4755 + SS YKE +K + I L +NQK++ S+++Y+E+ +KA Sbjct: 618 QQNISSVKYKE---EIKHATAISDPPELKRVK-ENQKNI-SNLQYKEQ--NYKAT----- 665 Query: 4756 SVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRL 4815 V P R R N ++L Y+ + + D E+ AK++QK +S + YR Sbjct: 666 PVSMTPEIERVRR----NQEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRG 721 Query: 4816 RLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRD 4875 +L + V+K + IS + Y D +KG + DTP + H K A + Sbjct: 722 QLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHIS 781 Query: 4876 DIKYKAHMLKTRN-DYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSV 4922 +KY KT+ + V D PV + K+ + +SDA Y + H V Sbjct: 782 MVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV 829 Score = 174 bits (440), Expect = 3e-42 Identities = 218/835 (26%), Positives = 374/835 (44%), Gaps = 84/835 (10%) Query: 863 DDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILH 922 +D M + K + SD Y+++++KSK T D + K A S+ YK + Sbjct: 35 EDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIK 94 Query: 923 S------YSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLE-------- 968 + Y P +I+ A + LQS+V YK +++ G+ + ++ Sbjct: 95 ADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDA---AKGFSDYAHMKEPPEVKHA 151 Query: 969 MEKAKRASDILNEKKYRQHPDTLKFTSIEDAP-ITVQSKINQAQRSDIAYKAKGEEIIHK 1027 ME K S+I K + DT +++ D P I + ++I++ S+ YK KG+ I++K Sbjct: 152 MEVNKHQSNISYRKDVQ---DTHTYSAELDRPDIKMATQISKII-SNAEYK-KGQGIMNK 206 Query: 1028 YNLPPDLPQFIQAKVNAYNISENMYKA----DLKDLSKKGYDLRTDAIPIRAAKAARQAA 1083 P F A + S+ YK ++KD KK + ++ R + A A Sbjct: 207 EPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKD--KKHHYNPLESASFRQNQLAATLA 264 Query: 1084 SDVQYKKDYEKAKGKMVGFQSLQDDPKLV---HYMNVAKIQSDREYKKDYEKTKSKYNTP 1140 S+V+YKKD + + D P L+ H + +K+ S REYKK +E+ K Y+ Sbjct: 265 SNVKYKKDIQNMH------DPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFD 318 Query: 1141 HDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLP-----DAMDLELSKNMMQIQSDNVYKED 1195 D + K + S V YK P + + SK ++QS+ VYKED Sbjct: 319 ADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKED 378 Query: 1196 YNNWMKGIGWIPIGSLDVEK------VKKAGDALNEKKYRQHPDT-LKFTSI-VDSPVM- 1246 + +KG SLD++K VK + L EK+Y++ + +K + ++S V+ Sbjct: 379 FEKEIKGRS-----SLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLD 433 Query: 1247 -VQAKQNTKQVSDILYKAKGEDVKHKYTMSP--DLPQFLQAKCNAYNISDVCYKRDWH-D 1302 +AK+ ++ S+ YK E + M D + AK A S+ YKRD + Sbjct: 434 IQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETE 493 Query: 1303 LIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKS-KGKHVGFRSLQDDPKLVHYMNV 1361 + KG V D + + AK + +AS +YK+ E KGK G + D P ++ Sbjct: 494 IKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGK--GMQVSMDIPDILRAKRT 551 Query: 1362 AKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSL 1421 +++ S R+YK E ++Y T D I K Q + V YK+ + T + D+ + Sbjct: 552 SEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEI 611 Query: 1422 EHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKF 1481 E + Q S YK+E I P E+++VK+ ++ +Y++ K Sbjct: 612 ERVKKNQQNISSVKYKEEI-KHATAISDPP----ELKRVKENQKNISNLQYKE--QNYKA 664 Query: 1482 TSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYK 1541 T V + + + N +QLS + YK GE + DP P+ +AK N N+S+ +Y+ Sbjct: 665 TPVSMTPEIERVRRNQEQLSAVKYK--GELQRGTAISDP--PELKRAKENQKNISNVYYR 720 Query: 1542 ADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVH 1601 + A + P+ + K+ NI+S KY + +++ KG+ L D P + H Sbjct: 721 GQLGR--ATTLSVTPEMERV--KKNQENISS-VKYTQDHKQMKGRPSLIL---DTPAMRH 772 Query: 1602 YMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVT-AAKKSQEVATNANYRQSYHH 1655 S +Y + +E +K + TP+ VT +K+ +V ++A Y+ + H Sbjct: 773 VKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 827 Score = 167 bits (423), Expect = 3e-40 Identities = 202/863 (23%), Positives = 360/863 (41%), Gaps = 114/863 (13%) Query: 1785 KAGWEEEKKKGYDLRP--DAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPK 1842 K G EE ++ +P + ++++ AR ++ SD +YK+ ++++K K + D P Sbjct: 17 KIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDK---CTFVTDSPM 73 Query: 1843 LVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNM 1902 L H + S+ +YK + A S + Y Sbjct: 74 LNHVKNIGAFISEAKYK-----------------GTIKADLSNSL------------YKR 104 Query: 1903 LPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKK--- 1959 +P + A + Q+QS+ YK + D KG E + K AME+ + Sbjct: 105 MPATIDSVFAGEVTQLQSEVAYKQKH-DAAKGFSDYA-HMKEPPEVKHAMEVNKHQSNIS 162 Query: 1960 YRQH-PDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIM--PDIPQIILA 2016 YR+ DT YS +D ++ +A +KI++ YK+ + ++ PD + Sbjct: 163 YRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAV-- 220 Query: 2017 KANAINMSDKLYKLSLEESKKKGYDLRP-DAIPIKAAKASRDIASDYKYKYNYEKGKGKM 2075 +A+ ++ K + E K K + P ++ + + + +AS+ KYK + + + Sbjct: 221 EASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPV 280 Query: 2076 VGFRSLEDDPKLV---HSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANI 2132 D P L+ H ++ +KM S REYKK +E K YH AD + K Sbjct: 281 ------SDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQ 334 Query: 2133 TNTNYKHLIHKYILLP-----DAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSL 2187 + YK K P + + + ++ ++QS+ YK+D+ + KG SL Sbjct: 335 SQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKG-----RSSL 389 Query: 2188 EVEKA------KKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDW 2241 +++K K T +++Y++ N K + VL Q A ++ ++ Sbjct: 390 DLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEY 449 Query: 2242 NKDKTKI------HVMPDTPDILQAKQNQTLYSQKLYKLGWEEALK-KGYDLPVDAISVQ 2294 KD I DT ++ AK+ + S+K YK E +K KG + D + VQ Sbjct: 450 KKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQ 509 Query: 2295 LAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWK 2354 AK + ++AS +YK+ ++ G + D P ++ + +++ S+R+YK + EK Sbjct: 510 RAKKASEMASQKQYKKDLENEIKGK-GMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKML 568 Query: 2355 TKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKS 2414 + +S+ D + K Q+ +S V YK + T + D ++ + KK + S YK Sbjct: 569 SNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKE 628 Query: 2415 DLEWLRGIGWSP-----------LGSL----------------EAEKNKRASEIISEKKY 2447 +++ I P + +L E E+ +R E +S KY Sbjct: 629 EIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKY 688 Query: 2448 RQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANL 2507 + R T+I D ++ AK N KN S+ YR + T + TP++ K N Sbjct: 689 KGELQRG--TAISDPPELKRAKENQKNISNVYYRGQLGRATT----LSVTPEMERVKKNQ 742 Query: 2508 INTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARN 2567 N S Y ++++K + L +D ++ K ++ S KY E F K G G Sbjct: 743 ENISSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGR--GFTP 799 Query: 2568 IEDDPKMMWSMHVAKIQSDREYK 2590 + DDP ++ SD YK Sbjct: 800 VVDDPVTERVRKNTQVVSDAAYK 822 Score = 166 bits (420), Expect = 7e-40 Identities = 220/949 (23%), Positives = 388/949 (40%), Gaps = 133/949 (14%) Query: 3181 DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYS 3240 D++ + V + L LA+ ++ Y E + K K + + D+P + + S Sbjct: 26 DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFIS 85 Query: 3241 ESLYRQAME-EAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHD 3299 E+ Y+ ++ + Y I V A + S+ YK+ + G A + + Sbjct: 86 EAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAH-MKE 144 Query: 3300 DPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHP--- 3356 P++ ++ + K QS+ Y+KD + T YS+ +D I +A + ++S+ +YK Sbjct: 145 PPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDIKMATQISKIISNAEYKKGQGI 203 Query: 3357 LHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWM---KGIGWVPIDSLEVVRAKRAGEL 3413 +++ + + D HA +A L S YK + K + P++S + + A L Sbjct: 204 MNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATL 263 Query: 3414 LSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIM 3473 S+ Y++ + + ++D P +L ++ L +K L Sbjct: 264 ASNVKYKKDIQNMH-DPVSDLPN-LLFLDHVLKASKML---------------------- 299 Query: 3474 LAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGH 3533 S + YK EE+K Y DA+ K + + S KYKE Y K G Sbjct: 300 ---------SGREYKKLFEENKGM-YHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGK 349 Query: 3534 HIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSD 3593 + + P S K+QS++ YK++FEK + K S +D Sbjct: 350 PM--LEFVETPSYQASKEAQKMQSEKVYKEDFEK-EIKGRSSLD---------------- 390 Query: 3594 IDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLE-WLRGIGWVPIGSV-EVEKVK 3651 L + + + +L + YK DLE ++G G V ++++ K Sbjct: 391 ------------LDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAK 438 Query: 3652 RAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPD 3711 RA E+ S+++Y++ D I+ K + D Sbjct: 439 RASEMASEKEYKK-----------DLESIIKGKG--------------------MQAGTD 467 Query: 3712 TPDILLAKSNSANISQKLYTKGWD-ESKMKDYDLRADAISIKSAKASRDIASDYKYKEAY 3770 T ++ AK + S+K Y + + E K K + D + ++ AK + ++AS +YK+ Sbjct: 468 TLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDL 527 Query: 3771 EKQ-KGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKK 3829 E + KG G Q D P I+ A +I S+R+YK E +K + +S+ D I K Sbjct: 528 ENEIKGK--GMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKT 585 Query: 3830 CQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPE 3889 Q ++ + Y+ + T + D +I + KK S YK +++ I PE Sbjct: 586 TQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHATAI----SDPPE 641 Query: 3890 VLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSI 3949 + RVK Q + Y+ N K T + TPE+ + N E +S KY+ + Sbjct: 642 LKRVKENQKNISNLQYKEQ--NYKATPVSMTPEIERVRRNQEQLSAVKYKGELQRGTA-- 697 Query: 3950 HIMPDTPEINLARANALNVSNKLYREGWDEMKAGCDVRLDAIP-IQAAKASREIASDYKY 4008 + D PE+ A+ N N+SN YR + G L P ++ K ++E S KY Sbjct: 698 --ISDPPELKRAKENQKNISNVYYRG-----QLGRATTLSVTPEMERVKKNQENISSVKY 750 Query: 4009 KLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPV--DMLSI 4066 DH++ KG L D +R A + +Y D+ K K + +PV D ++ Sbjct: 751 TQDHKQMKGRPSLIL---DTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTE 807 Query: 4067 LHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKAD 4115 KN+Q +VSD Y+ M + +I K + +++ D Sbjct: 808 RVRKNTQ-VVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLD 855 Score = 165 bits (417), Expect = 2e-39 Identities = 215/851 (25%), Positives = 357/851 (41%), Gaps = 67/851 (7%) Query: 305 DNISTRKYQEDFENMKDQIYFMQT-ETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNV 363 D K E+ EN +DQ+++ E ++ +K S ++YKE+++K+K K + Sbjct: 11 DETEEEKIGEE-ENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTF-- 67 Query: 364 LPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTV----LQNFSSD 419 +++P L +K G +S+ YK + + S+ Y P +D+V + S+ Sbjct: 68 --VTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSL-YKRMPA-TIDSVFAGEVTQLQSE 123 Query: 420 KKYKDSY-LKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQE 478 YK + Y E P H M+V S+ +Y+ + ++ T + E Sbjct: 124 VAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQD-------THTYSAE 176 Query: 479 YEA--IKKLDQCKDHTYKVHPDK-----TKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHE 531 + IK Q K K V P A SK S + YK K + Sbjct: 177 LDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFD 236 Query: 532 SE-KFKCH--IPPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKAN 588 +E K K H P ++ +F Q+++ A S+ YK+D + D+ + + L Sbjct: 237 NEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLP-NLLFLDHVLKA 295 Query: 589 TKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSM- 647 +K S YKK +E+NKG D + LH A QS YKE YEK K K M Sbjct: 296 SKMLSGREYKKLFEENKGM---YHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPML 352 Query: 648 NYCETPKYQLDTQLKNF-SEARYKDLYVKDVLGHYVGSME-DPYHTHCMKVAAQNSDKSY 705 + ETP YQ + + SE YK+ + K++ G ++ P H + +K Y Sbjct: 353 EFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEY 412 Query: 706 KAEYE-EDKGKCYFPQTITQEYEAIKKL-DQCKDHTYKVHPDK----TKFTAVTDSPVLL 759 K + E E KGK + + + K+ + + YK + A TD+ + Sbjct: 413 KKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQ 472 Query: 760 QAQLNTKQLSDLNYKAKHEGE-KFK-CHIPADAPQFIQHRVNAYNLSDNVYKQDWEKS-K 816 A+ + S+ +YK E E K K + D + + + S YK+D E K Sbjct: 473 HAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIK 532 Query: 817 AKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKN 876 K + +D +L A K TS++ ++ Y+ KM+ S D + +KT + Sbjct: 533 GKGMQVSMDIPDILRA----KRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQ 588 Query: 877 QSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLA 936 + Y+K TA D ++ + KK+Q S V YK + + D + Sbjct: 589 NISAVF---YKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHATAISDPPELKRV 645 Query: 937 KKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSI 996 K+ S+++YK + N P E+E+ +R + L+ KY+ + + T+I Sbjct: 646 KENQKNISNLQYK-EQNYKATPVSMTP----EIERVRRNQEQLSAVKYK--GELQRGTAI 698 Query: 997 EDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADL 1056 D P ++K NQ S++ Y+ + + + P+ + K N NIS Y D Sbjct: 699 SDPPELKRAKENQKNISNVYYRGQ----LGRATTLSVTPEMERVKKNQENISSVKYTQDH 754 Query: 1057 KDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMN 1116 K + K L D +R K A+ S V+Y +D+EK KG+ GF + DDP Sbjct: 755 KQM-KGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGR--GFTPVVDDPVTERVRK 811 Query: 1117 VAKIQSDREYK 1127 ++ SD YK Sbjct: 812 NTQVVSDAAYK 822 Score = 165 bits (417), Expect = 2e-39 Identities = 193/735 (26%), Positives = 315/735 (42%), Gaps = 73/735 (9%) Query: 91 KMQDLFSPNKYKEKFEKTKG-QPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICH 149 ++ L S YK+K + KG YA + PE++ +V S + YR D T Sbjct: 116 EVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYS- 174 Query: 150 VDEKAKDIEHAKKVSQQVSKVLYK--QNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKLY 207 + DI+ A ++S+ +S YK Q + + + PD V+A K ++ K Sbjct: 175 AELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEK 234 Query: 208 TEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAK- 266 ++ DK Y +S R+ A S+V YKK + Q P++D P++ F Sbjct: 235 FDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDI---QNMHDPVSDLPNLLFLDH 291 Query: 267 --KVTNQVSKQKYKEDYENKIKGKWS-ETPCFEVANARMNADNISTRKYQEDFENMKDQI 323 K + +S ++YK+ +E KG + + E + + NA S KY+E++E K + Sbjct: 292 VLKASKMLSGREYKKLFEEN-KGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKP 350 Query: 324 YFMQTETPEYKMNKKAGVAASKVKYKEDYEKN-KGKADYNVLPASENPQLRQLKAAGDAL 382 ETP Y+ +K+A S+ YKED+EK KG++ L + P+ +K + L Sbjct: 351 MLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSS---LDLDKTPEFLHVKYITNLL 407 Query: 383 SDKLYK---ENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFE 439 +K YK EN K K +N E + +S+K+YK I G + + Sbjct: 408 REKEYKKDLENEIKGKGMELN-SEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGT 466 Query: 440 DPYH-SHCMKVTAQNSDKNYKAEYE-EDRGKGFFPQTITQEYEAIKKL-DQCKDHTYKVH 496 D H K S+K+YK + E E +GKG T T + + KK + YK Sbjct: 467 DTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKD 526 Query: 497 PD---KTKFTQVT-DSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVN 552 + K K QV+ D P +L+A+ S+ S YK + E DTP + K Sbjct: 527 LENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTT 586 Query: 553 AYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVL 612 N+S YK++ A K +++ + K N +N S V YK++ + Sbjct: 587 QQNISAVFYKKEVGAGTAVKDSPEIERV-----KKNQQNISSVKYKEEIKH-------AT 634 Query: 613 SINDDPKMLHSLKVAKNQSDRLYKE-NYEKTKA----------KSMNYCETPKYQLDTQ- 660 +I+D P++ + KN S+ YKE NY+ T ++ KY+ + Q Sbjct: 635 AISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKGELQR 694 Query: 661 ---------LKNFSE--ARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEY 709 LK E ++Y + LG P K S Y ++ Sbjct: 695 GTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDH 754 Query: 710 EEDKGKCYFPQTITQEYEAIKKLDQCKDH--TYKVHPD--KTK---FTAVTDSPVLLQAQ 762 ++ KG+ ++ + A++ + + ++H K H D KTK FT V D PV + + Sbjct: 755 KQMKGR----PSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVR 810 Query: 763 LNTKQLSDLNYKAKH 777 NT+ +SD YK H Sbjct: 811 KNTQVVSDAAYKGVH 825 Score = 163 bits (412), Expect = 6e-39 Identities = 217/935 (23%), Positives = 389/935 (41%), Gaps = 135/935 (14%) Query: 1947 KNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHI 2006 K++ E I E++ + D + Y +++ ++M LA+ +++++ YK+ ++ K K Sbjct: 10 KDETEEEKIGEEENEE--DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTF 67 Query: 2007 MPDIPQIILAKANAINMSDKLYKLSLEESKKKG-YDLRPDAIPIKAAKASRDIASDYKYK 2065 + D P + K +S+ YK +++ Y P I A + S+ YK Sbjct: 68 VTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYK 127 Query: 2066 YNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAA 2125 ++ KG + +++ P++ H+M+V K QS+ Y+K+ ++T Sbjct: 128 QKHDAAKG-FSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDT---------------- 170 Query: 2126 KDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPA- 2184 H Y D +I++ +++I S+ EYK+ K PA Sbjct: 171 ----------------HTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNK----EPAV 210 Query: 2185 -GSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYT-IDWN 2242 G + E A +A++ +S KY++ N K + A + + L + + + Sbjct: 211 IGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYK 270 Query: 2243 KDKTKIH-VMPDTPDIL---QAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKA 2298 KD +H + D P++L + + S + YK +EE K Y DA+ K Sbjct: 271 KDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEEN-KGMYHFDADAVEHLHHKG 329 Query: 2299 SRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFS 2358 + + S KYK+ Y K G + + P S KMQSE+ YK+DFEK + K Sbjct: 330 NAVLQSQVKYKEEYEKNKGKPM--LEFVETPSYQASKEAQKMQSEKVYKEDFEK-EIKGR 386 Query: 2359 SPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLE- 2417 S +D+ K E +LH K + L E YK DLE Sbjct: 387 SSLDL------DKTPE---------FLH-------------VKYITNLLREKEYKKDLEN 418 Query: 2418 WLRGIGWSPLGS--LEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNR 2475 ++G G L S L+ ++ KRASE+ SEK+Y++ D I+ K Sbjct: 419 EIKGKGME-LNSEVLDIQRAKRASEMASEKEYKK-----------DLESIIKGKG----- 461 Query: 2476 SDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYE-ELKRKGYDLPVDAI 2534 + DT ++ AK S+K Y+ E E+K KG + D + Sbjct: 462 ---------------MQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTL 506 Query: 2535 PIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFE 2594 ++ AK + E+AS+ +YK+ ++ G + D P ++ + ++I S R+YK + E Sbjct: 507 DVQRAKKASEMASQKQYKKDLENEIKGK-GMQVSMDIPDILRAKRTSEIYSQRKYKDEAE 565 Query: 2595 KWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNL 2654 K + +S+ D + K Q +S V YK + T + D ++ ++ S Sbjct: 566 KMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVK 625 Query: 2655 YKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLAKNN 2714 YK +++ I S E ++ K + +S+ Y++ +K + + + + + N Sbjct: 626 YKEEIKHATAI----SDPPELKRVKENQKNISNLQYKE--QNYKATPVSMTPEIERVRRN 679 Query: 2715 AITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRV 2774 ++ Y + + D PE+ AK+N+ N S Y+ L A + Sbjct: 680 QEQLSAVKYKGELQRGTA----ISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEM 735 Query: 2775 DAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKK 2834 + + K +++ S KY + +++ G I D P M S +Y + Sbjct: 736 ERV-----KKNQENISSVKYTQDHKQMKGR---PSLILDTPAMRHVKEAQNHISMVKYHE 787 Query: 2835 DFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDYK 2868 DFEK K + F+ VD +K +VSD YK Sbjct: 788 DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822 Score = 155 bits (392), Expect = 1e-36 Identities = 170/699 (24%), Positives = 307/699 (43%), Gaps = 57/699 (8%) Query: 32 YETTTTRTSDYEQSETSKPALAQPALAQPASAKPVERRKVIRK-----KVDPSKFMTPYI 86 +++ + D + + T L +P + + +K +P+ P Sbjct: 157 HQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDF 216 Query: 87 AHSQKMQDLFSPNKYKEKFE---KTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDV 143 H+ + L S KYKEKF+ K K Y + ++ R+ + S VKY+ D Sbjct: 217 EHAVEASKLSSQIKYKEKFDNEMKDKKHHY-NPLESASFRQNQLAATLASNVKYKKD--- 272 Query: 144 AKTICHVDEKAKD------IEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVK 197 I ++ + D ++H K S+ +S YK+ +E+ K Y DA E + Sbjct: 273 ---IQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKG 329 Query: 198 NTAMFSKKLYTEDWEADKSL-FYPYNDSPELRRVAQAQKALSDVAYKKGLAEQ--QAQFT 254 N + S+ Y E++E +K + ++P + +AQK S+ YK+ ++ Sbjct: 330 NAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSL 389 Query: 255 PLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSE--TPCFEVANARMNADNISTRKY 312 L P+ K +TN + +++YK+D EN+IKGK E + ++ A+ ++ S ++Y Sbjct: 390 DLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEY 449 Query: 313 QEDFEN-MKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKN-KGKADYNVLPASENP 370 ++D E+ +K + T+T E + KKA AS+ YK D E KGK + +++ Sbjct: 450 KKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGK---GMQVSTDTL 506 Query: 371 QLRQLKAAGDALSDKLYKENYE-KTKAKSINY-CETPKFKLDTVLQNFSSDKKYKDSYLK 428 +++ K A + S K YK++ E + K K + + P S +KYKD K Sbjct: 507 DVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEK 566 Query: 429 DILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQC 488 +L +Y + D +K T QN + Y+++ G G + + E E +KK +Q Sbjct: 567 -MLSNY-STIADTPEIQRIKTTQQNISAVF---YKKEVGAGTAVKD-SPEIERVKK-NQQ 619 Query: 489 KDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQ 548 + K + T ++D P L + + N K +S+L YK + +K TP + Sbjct: 620 NISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQYK----EQNYKATPVSMTPEIER 675 Query: 549 HKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKM 608 + N LS YK + ++ A D L AK N KN S+V Y +G++ Sbjct: 676 VRRNQEQLSAVKYKGELQRGTAIS-----DPPELKRAKENQKNISNVYY-------RGQL 723 Query: 609 IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKN-FSEA 667 +++ P+M K +N S Y +++++ K + +TP + + +N S Sbjct: 724 GRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMV 783 Query: 668 RYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYK 706 +Y + + K + ++DP K SD +YK Sbjct: 784 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822 Score = 153 bits (387), Expect = 5e-36 Identities = 205/877 (23%), Positives = 351/877 (40%), Gaps = 106/877 (12%) Query: 204 KKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIE 263 +K+ E+ E D+ + P + + + + +SD+ YK+ + + + T + D P + Sbjct: 16 EKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLN 75 Query: 264 FAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQI 323 K + +S+ KYK + AD + + + Sbjct: 76 HVKNIGAFISEAKYK---------------------GTIKAD-------------LSNSL 101 Query: 324 YFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALS 383 Y T + + S+V YK+ ++ KG +DY + E P+++ S Sbjct: 102 YKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHM--KEPPEVKHAMEVNKHQS 159 Query: 384 DKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYH 443 + Y+++ + T S + P K+ T + S+ +YK + I+ P Sbjct: 160 NISYRKDVQDTHTYSAE-LDRPDIKMATQISKIISNAEYKKG--QGIMNKEPAVIGRPDF 216 Query: 444 SHCMKVTAQNSDKNYKAEYE-EDRGKGFFPQTITQEYEAIKKLDQCKDHTYKVHPD-KTK 501 H ++ + +S YK +++ E + K + +L K D + Sbjct: 217 EHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNM 276 Query: 502 FTQVTDSPVLL---QAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSD 558 V+D P LL SK LS YK E K H D + HK NA S Sbjct: 277 HDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQ 336 Query: 559 NLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKN-KGKMIGVLSINDD 617 YK+++EK+K K V+ A+K K S+ +YK+D+EK KG+ L ++ Sbjct: 337 VKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGR--SSLDLDKT 394 Query: 618 PKMLHSLKVAKNQSDRLYKENYE-KTKAKSMNYCETPKYQLDTQ-LKNFSEARYKDLYVK 675 P+ LH + ++ YK++ E + K K M E LD Q K SE + Y K Sbjct: 395 PEFLHVKYITNLLREKEYKKDLENEIKGKGM---ELNSEVLDIQRAKRASEMASEKEYKK 451 Query: 676 DVLGHYVG-SMEDPYHT----HCMKVAAQNSDKSYKAEYE-EDKGKCYFPQTITQEYEAI 729 D+ G M+ T H K A S+K YK + E E KGK T T + + Sbjct: 452 DLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRA 511 Query: 730 KKL-DQCKDHTYKVHPD---KTKFTAVT-DSPVLLQAQLNTKQLSDLNYKAKHEGEKFKC 784 KK + YK + K K V+ D P +L+A+ ++ S YK + E Sbjct: 512 KKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNY 571 Query: 785 HIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMY 844 AD P+ + + N+S YK++ A K +++ + K N +N S V Y Sbjct: 572 STIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERV-----KKNQQNISSVKY 626 Query: 845 KKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIY----------- 893 K++ + A +I+D P++ + KN S+ +Y++ K+ + Sbjct: 627 KEEIKH-------ATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRN 679 Query: 894 ----------------TAPLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAK 937 TA D ++ +AK++Q S+V Y+ L + + ++ K Sbjct: 680 QEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVK 739 Query: 938 KAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLK---FT 994 K S V+Y D+ MKG + + M K A + ++ KY + + K FT Sbjct: 740 KNQENISSVKYTQDHKQ-MKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFT 798 Query: 995 SIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLP 1031 + D P+T + + N SD AYK I+ P Sbjct: 799 PVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRP 835 Score = 149 bits (375), Expect = 1e-34 Identities = 183/805 (22%), Positives = 325/805 (40%), Gaps = 100/805 (12%) Query: 4288 YKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYR--------NYLHQWMCHPDQNDV 4339 YKE++ K+K K D + K +S+ Y+ N L++ M P D Sbjct: 54 YKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRM--PATIDS 111 Query: 4340 IQARKAYDLQSDNVYRADLEWLRGIGWI-----PLDSVDHVRVTKNQEMMSQIKYKKNAL 4394 + A + LQS+ Y+ + +G P + + V K+Q S I Y+K+ Sbjct: 112 VFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQ---SNISYRKDVQ 168 Query: 4395 ENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDT---PHISHSKDMG 4451 + + + + +D P+I +A S S+ +YK K +G P P H+ + Sbjct: 169 DTH-TYSAELDRPDIKMATQISKIISNAEYK----KGQGIMNKEPAVIGRPDFEHAVEAS 223 Query: 4452 KLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKH-----ADLVNSELKYKETYEKQKGHY 4506 KL S I YK ++ Y P+ A A + S +KYK+ + Sbjct: 224 KLSSQIKYKEKFDNEMK---DKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDP- 279 Query: 4507 LAGKVIGEFPGVV---HCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYIL 4563 + + P ++ H L KM S Y+K +E+ K H D + H+ K + Sbjct: 280 -----VSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQ 334 Query: 4564 SDLEYRHYFHQ-----WTSLLEEPNVIRVRNAQEILSDNVYKDDLNW-LKGIGCYVWD-T 4616 S ++Y+ + + +E P+ + AQ++ S+ VYK+D +KG D T Sbjct: 335 SQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKT 394 Query: 4617 PQILHAKKSYDLQSQLQYTAAGKENLQN------YNLVTDTPLYVTAVQSGINASEVKYK 4670 P+ LH K +L + +Y K++L+N L ++ A ++ ASE +YK Sbjct: 395 PEFLHVKYITNLLREKEY----KKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYK 450 Query: 4671 ENYHQI-KDKYTTV-LETVDYDRTRNLKNLYSSNLYKEAWD-RVKATSYILPSSTLSLTH 4727 ++ I K K +T++ + + S YK + +K + + TL + Sbjct: 451 KDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQR 510 Query: 4728 AKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKM 4787 AK +AS +Y+++ E + S+D P+ R R ++ R Y+ EK Sbjct: 511 AKKASEMASQKQYKKDLENEIKGKGMQVSMDI-PDILRAKRTSEIYSQRKYKDEAEKMLS 569 Query: 4788 KIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDD 4847 + D E+ K +Q+ +S + Y+ + D + V+K IS + YK++ Sbjct: 570 NYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEE 629 Query: 4848 LNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKT-------------RNDYKL-- 4892 + I D PE+ K +++YK K RN +L Sbjct: 630 IKHATAIS----DPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSA 685 Query: 4893 ------------VTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALH 4940 ++D P +A ++ K +S+ Y G+ + T +++R Sbjct: 686 VKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL-----GRATTLSVTPEMERVKK 740 Query: 4941 AYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLG 5000 + SS Y + + L DTP +H+K+ + S KY E +E TK G+T Sbjct: 741 NQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPV 800 Query: 5001 PKDVPFVHVRRVNNVTSERLYRELY 5025 D VR+ V S+ Y+ ++ Sbjct: 801 VDDPVTERVRKNTQVVSDAAYKGVH 825 Score = 147 bits (371), Expect = 3e-34 Identities = 202/859 (23%), Positives = 368/859 (42%), Gaps = 124/859 (14%) Query: 1412 YTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNERK 1471 Y + + +S+E R ++ SD YK+E+ ++ S + VK G ++E K Sbjct: 30 YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFV-TDSPMLNHVKNIGAFISEAK 88 Query: 1472 YRQHPDTVK-------FTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLK--HKYTIDPEL 1522 Y+ T+K + +P ++ V A T+ S++ YK + + K Y E Sbjct: 89 YK---GTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEP 145 Query: 1523 PQFIQAKVNALNMSDAHYKADWKKTIAKGYDL-RPDAIPIVAAKSSRNIASDCKYKEAYE 1581 P+ A + S+ Y+ D + T +L RPD I A I S+ +YK Sbjct: 146 PEVKHAMEVNKHQSNISYRKDVQDTHTYSAELDRPD---IKMATQISKIISNAEYK---- 198 Query: 1582 KAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYE---ASKTKYHTPLDMVSVTAAK 1638 K +G ++ P H + +K+ S +YK+ ++ K ++ PL+ S + Sbjct: 199 KGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQ 258 Query: 1639 KSQEVATNANYRQSYHH----YTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWV 1694 + +A+N Y++ + + LP+ L ++H A ++ S YK F KG+ Sbjct: 259 LAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEE-NKGMYHF 317 Query: 1695 PIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTME----QALNKSNKLNMDKRLYT 1750 +++E K + S+ KY++ EK K ++ +E QA ++ K+ +K +Y Sbjct: 318 DADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEK-VYK 376 Query: 1751 EKWNKD---KTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEE-KKKGYDLRPDAIAIK 1806 E + K+ ++++ + TP+ L + + +K YK E E K KG +L + + I+ Sbjct: 377 EDFEKEIKGRSSLD-LDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQ 435 Query: 1807 AARASRDIASDYKYKKAYEQ-AKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYE-- 1863 A+ + ++AS+ +YKK E KGK G ++ D ++ H + A++ S+++YK+ E Sbjct: 436 RAKRASEMASEKEYKKDLESIIKGK--GMQAGTDTLEMQHAKKAAEIASEKDYKRDLETE 493 Query: 1864 -KSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDN 1922 K K D L V AKK+ E+A S Sbjct: 494 IKGK-GMQVSTDTLDVQRAKKASEMA-------------------------------SQK 521 Query: 1923 QYKADYADFMKGIGW-LPLGSLEAEKNKKAMEIISEKKYRQHPDTL--KYSTLMDSMNMV 1979 QYK D + +KG G + + + + K+ EI S++KY+ + + YST+ D+ + Sbjct: 522 QYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQ 581 Query: 1980 LAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKG 2039 + + ++ YK+ A + D P+I K N N+S YK ++ + Sbjct: 582 RIKTTQQNISAVFYKKEVGAGTA----VKDSPEIERVKKNQQNISSVKYKEEIKHATAIS 637 Query: 2040 YDLRPDAIPIKAAKASRDIASDYKYK-YNYE-----------------------KGKGKM 2075 D +K K ++ S+ +YK NY+ K KG++ Sbjct: 638 -----DPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKGEL 692 Query: 2076 VGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANITNT 2135 ++ D P+L + + K S+ Y+ T TP + K Q NI++ Sbjct: 693 QRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTP----EMERVKKNQENISSV 748 Query: 2136 NY----KHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEV-E 2190 Y K + + L+ D + + S +Y +D+ E KG G++P V E Sbjct: 749 KYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDF-EKTKGRGFTPVVDDPVTE 807 Query: 2191 KAKKATEYASDQKYR-QHP 2208 + +K T+ SD Y+ HP Sbjct: 808 RVRKNTQVVSDAAYKGVHP 826 Score = 146 bits (368), Expect = 8e-34 Identities = 220/947 (23%), Positives = 389/947 (41%), Gaps = 148/947 (15%) Query: 2674 EDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTT 2733 ED K++ + + + DQ + +++ + M LA+ ++ Y E + K K Sbjct: 7 EDIKDETEEEKIGEE--ENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDK 64 Query: 2734 VHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDA-IPIKAAKASRDIASEF 2792 + D+P + K SE YK ++ R+ A I A + SE Sbjct: 65 CTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEV 124 Query: 2793 KYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGV 2852 YK+ + G A +++ P++ +M V K QS+ Y+KD + T +S+ +D + Sbjct: 125 AYKQKHDAAKGFSDYAH-MKEPPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDI 182 Query: 2853 VLAKKCQTLVSDVDYKN---YLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIG 2909 +A + ++S+ +YK +++ + + D HA +A L S YK Sbjct: 183 KMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKE--------- 233 Query: 2910 WVSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEA 2969 K E+ K + P + F + L LA N Sbjct: 234 ------------KFDNEMKDKKHHYNPLESASFRQ--NQLAATLASN-----------VK 268 Query: 2970 WDKDKTQIHI-MPDTPEIMLARQNKINYSETL----YKLANEEAKKKGYDLRSDAIPIVA 3024 + KD +H + D P ++ + + S+ L YK EE K Y +DA+ + Sbjct: 269 YKKDIQNMHDPVSDLPNLLFL-DHVLKASKMLSGREYKKLFEENKGM-YHFDADAVEHLH 326 Query: 3025 AKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKT 3084 K + + S KYK+ Y K G + + P S K+QS++ YK+DFEK + Sbjct: 327 HKGNAVLQSQVKYKEEYEKNKGKPM--LEFVETPSYQASKEAQKMQSEKVYKEDFEK-EI 383 Query: 3085 KFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSD 3144 K S +D L + +H + +L + YK D Sbjct: 384 KGRSSLD----------------------------LDKTPEFLHVKYITNLLREKEYKKD 415 Query: 3145 LQ-WLRGIGWVPIGS--MDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNA 3201 L+ ++G G + + S +D+ + KRA+E+ S+ Y++ LE ++ K Sbjct: 416 LENEIKGKG-MELNSEVLDIQRAKRASEMASEKEYKK------------DLESII-KGKG 461 Query: 3202 LNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAME-EAKKEGYDLRS 3260 + DT E+ A++ SE Y++ +E E K +G + + Sbjct: 462 MQAGT------------------DTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVST 503 Query: 3261 DAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKK 3320 D + + AK + ++AS +YK+ ++ G + D P I+ + +++ S R+YK Sbjct: 504 DTLDVQRAKKASEMASQKQYKKDLENEIKGK-GMQVSMDIPDILRAKRTSEIYSQRKYKD 562 Query: 3321 DFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQS 3380 + EK + YS+ D I K Q +S V YK + + D +I +K S Sbjct: 563 EAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNIS 622 Query: 3381 DNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLA 3440 YK +++ I D E+ R K + +S+ Y++ + K T ++ TPE Sbjct: 623 SVKYKEEIKHATAIS----DPPELKRVKENQKNISNLQYKE--QNYKATPVSMTPEIERV 676 Query: 3441 KNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYD 3500 + N ++L + + + + D PE+ AK N+ N S+ Y+ L G Sbjct: 677 RRN----QEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL------GRA 726 Query: 3501 LRLDAIP-IQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQ--- 3556 L P ++ K +++ S KY + +++ G I D P M HV + Q Sbjct: 727 TTLSVTPEMERVKKNQENISSVKYTQDHKQMKGR---PSLILDTPAMR---HVKEAQNHI 780 Query: 3557 SDREYKKEFEKWKTKFSSPV--DMLGVVLAKKCQILVSDIDYK--HP 3599 S +Y ++FEK K + +PV D + + K Q+ VSD YK HP Sbjct: 781 SMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV-VSDAAYKGVHP 826 Score = 146 bits (368), Expect = 8e-34 Identities = 192/859 (22%), Positives = 355/859 (41%), Gaps = 133/859 (15%) Query: 3914 YTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINLARANALNVSNKLY 3973 Y +++ + LA+ E IS +Y+E + K K + D+P +N + +S Y Sbjct: 30 YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKY 89 Query: 3974 REGWD-EMKAGCDVRLDA-IPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDNKI 4031 + ++ R+ A I A ++ S+ YK H+ KG + ++ ++ Sbjct: 90 KGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG-FSDYAHMKEPPEV 148 Query: 4032 RWALIADKLQNEREYRLDWAK---WKAKIQSPVDMLSILHSKNSQALVSDMDYRN---YL 4085 + A+ +K Q+ YR D + A++ P ++ SK ++S+ +Y+ + Sbjct: 149 KHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISK----IISNAEYKKGQGIM 204 Query: 4086 HQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWL---RGIGWMPNDSVSVNHAKHAADIF 4142 ++ + + D A +A +L S YK + + + P +S S + AA + Sbjct: 205 NKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLA 264 Query: 4143 SEKKYRTKIETLNFTPVD-------------------------------------DRVDY 4165 S KY+ I+ ++ D D V++ Sbjct: 265 SNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEH 324 Query: 4166 VTAKQSGEILDDIKYRKDWNATKSKYTL--TETPLLHTAQEAARILDQYLYKEGWERQKA 4223 + K + + +KY++++ K K L ETP ++EA ++ + +YKE +E++ Sbjct: 325 LHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIK 384 Query: 4224 TGYILPPDAVP-FVHAHHCNDVQSELKYKAE---HVKQKGHYVGVPTMRDDPKLVWFEHA 4279 L D P F+H + ++ E +YK + +K KG + + + + A Sbjct: 385 GRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVL----DIQRAKRA 440 Query: 4280 GQIQNERLYKEDYHKT-KAK-INIPADMVSVLAAKQGQTLVSDIDYRNYLHQ------WM 4331 ++ +E+ YK+D K K + D + + AK+ + S+ DY+ L Sbjct: 441 SEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQ 500 Query: 4332 CHPDQNDVIQARKAYDLQSDNVYRADLE-WLRGIGW-IPLDSVDHVRVTKNQEMMSQIKY 4389 D DV +A+KA ++ S Y+ DLE ++G G + +D D +R + E+ SQ KY Sbjct: 501 VSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKY 560 Query: 4390 KKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKD 4449 K A + N+ ++ D PEI K N S V YK K G T D+P I K Sbjct: 561 KDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYK----KEVGAGTAVKDSPEIERVKK 616 Query: 4450 MGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAG 4509 + S++ YK KHA ++ + K E QK Sbjct: 617 NQQNISSVKYKEE--------------------IKHATAISDPPELKRVKENQKN----- 651 Query: 4510 KVIGEFPGVVHCLDFQKMRSALNYR-KHYEDTKANVHIPNDMMNHV-LAKRCQYILSDLE 4567 S L Y+ ++Y+ T P M + +R Q LS ++ Sbjct: 652 ------------------ISNLQYKEQNYKAT------PVSMTPEIERVRRNQEQLSAVK 687 Query: 4568 YRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYD 4627 Y+ + T++ + P + R + Q+ +S+ Y+ L G + TP++ KK+ + Sbjct: 688 YKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL----GRATTLSVTPEMERVKKNQE 743 Query: 4628 LQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDK-YTTVLET 4686 S ++YT K+ +L+ DTP ++ + S VKY E++ + K + +T V++ Sbjct: 744 NISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDD 803 Query: 4687 VDYDRTRNLKNLYSSNLYK 4705 +R R + S YK Sbjct: 804 PVTERVRKNTQVVSDAAYK 822 Score = 137 bits (346), Expect = 3e-31 Identities = 200/872 (22%), Positives = 370/872 (42%), Gaps = 98/872 (11%) Query: 2341 QSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYL----HQWTCLPDQND 2396 + E+ +++ E+ + + ++ L + LA+KC EL+SD+ YK + T + D Sbjct: 14 EEEKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPM 73 Query: 2397 VVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKF 2456 + K + SE YK G+++A+ +S Y++ Sbjct: 74 LNHVKNIGAFISEAKYK--------------GTIKAD--------LSNSLYKR------- 104 Query: 2457 TSIPDAMDIVLAKTNAKNRSDRLYREAWDKDK--TQIHIMPDTPDIVLAKANLINTSDKL 2514 +P +D V A + +S+ Y++ D K + M + P++ A + S+ Sbjct: 105 --MPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNIS 162 Query: 2515 YRMGYEELKRKGYDLPVDAIPIKAAKASREIAS--EYKYKEGFRKQLGHHIGARNIEDDP 2572 YR ++ Y +D IK A +I S EYK +G + IG + E Sbjct: 163 YRKDVQDTHT--YSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEH-- 218 Query: 2573 KMMWSMHVAKIQSDREYKKDFE---KWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLH 2629 ++ +K+ S +YK+ F+ K K +P++ + TL S+V YK + Sbjct: 219 ----AVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQ 274 Query: 2630 QW----TCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQIL 2685 + LP+ + H +A + S YK + KG+ + ++E +K + Sbjct: 275 NMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQ 334 Query: 2686 SDHVYRQHPDQFKFSSLMDSI--PMVLAKNNAITM-NHRLYTEAWDKD---KTTVHIMPD 2739 S Y++ ++ K +++ + P A A M + ++Y E ++K+ ++++ + Sbjct: 335 SQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLD-LDK 393 Query: 2740 TPEVLLAKQNKVNYSEKLYKLGLE-EAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGY 2798 TPE L K EK YK LE E K KG ++ + + I+ AK + ++ASE +YK+ Sbjct: 394 TPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDL 453 Query: 2799 RKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFE-KWKTK-FSSPVDMLGVVLAK 2856 + G +A D +M + A+I S+++YK+D E + K K D L V AK Sbjct: 454 ESIIKGK-GMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAK 512 Query: 2857 KCQTLVSDVDYKNYLHQ------WTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGW 2910 K + S YK L D D++ A++ ++ S YK + + M Sbjct: 513 KASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYS 572 Query: 2911 VSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAW 2970 + ++++ K + +S Y++ + T+V DS E K N N++ Y E Sbjct: 573 TIADTPEIQRIKTTQQNISAVFYKK--EVGAGTAVKDSPEIERVKKNQQNISSVKYKEE- 629 Query: 2971 DKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRD 3030 K T I D PE+ ++N+ N S YK N +A S I + +++ Sbjct: 630 IKHATAI---SDPPELKRVKENQKNISNLQYKEQNYKATPV-----SMTPEIERVRRNQE 681 Query: 3031 VISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPV 3090 +S KYK ++ I D P++ + K S+ Y+ + T +P Sbjct: 682 QLSAVKYKGELQR-------GTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTP- 733 Query: 3091 DMLGVVLAKKCQTLVSDV----DYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQ 3146 + KK Q +S V D+K + + D + H ++A + S Y D + Sbjct: 734 ---EMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFE 790 Query: 3147 WLRGIGWVPIGSMDVV-KCKRAAEILSDNIYR 3177 +G G+ P+ V + ++ +++SD Y+ Sbjct: 791 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822 >gi|169217576 PREDICTED: similar to nebulin [Homo sapiens] Length = 410 Score = 503 bits (1295), Expect = e-141 Identities = 238/396 (60%), Positives = 312/396 (78%) Query: 3472 IMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQL 3531 ++ A +N + S+KLY+ ++K++GYD+R DAI I+ AKASR+IAS+YKYKEGYRKQL Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 3532 GHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILV 3591 GHH+G R ++DDPK +W+IH AKIQSDREYKK +EK K ++P+DM+ +V AKKCQ+LV Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 3592 SDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVK 3651 SDIDY++ LH+WTCLPDQNDVIQA+KAYDLQSD +YKSDLEWL+GIGW+P GSVEV +VK Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 3652 RAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPD 3711 A +L++R YR + LKFT I DTPE++ AK NA+ +S+ LY AW+ +K +++V D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 3712 TPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYE 3771 TP +L +K N+ IS K Y + W++ KM YDLRADAI I+ AKASRDIASDY YK AYE Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 3772 KQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQ 3831 KQKGH+IG +S ++DPK++ A + K+Q++R YKK + K K S PVDM+SI AK+ Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 3832 TLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSD 3867 L +D+DYR+YLH W+C PDQND+IQA+KAYDLQSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 501 bits (1291), Expect = e-141 Identities = 240/396 (60%), Positives = 310/396 (78%), Gaps = 1/396 (0%) Query: 3715 ILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQK 3774 +L A N+ IS KLY K W+++K K YD+RADAI IK AKASR+IAS+YKYKE Y KQ Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 3775 GHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLV 3834 GHH+G ++++DDPK + AIHA KIQS+REYKK ++K K ++P+DM+SI+ AKKCQ LV Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 3835 TDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVK 3894 +DIDYRNYLH+WTC+PDQND+IQAKKAYDLQSD LYK+DLEWL+GIGW+P+GS EV+RVK Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 3895 NAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPD 3954 NAQN+ + +YR LK+TSIVDTPEV+ AK NA IS P YR W+K+K ++++ D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 3955 TPEINLARANALNVSNKLYREGWDEMK-AGCDVRLDAIPIQAAKASREIASDYKYKLDHE 4013 TP + ++ NAL +SNK Y++ W+++K G D+R DAI IQ AKASR+IASDY YK +E Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 4014 KQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQ 4073 KQKGHY+G +A++D K+ WA K+QN+R Y+ + KAKI PVDM+SI +K Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 4074 ALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSD 4109 AL SD+DYR+YLH W+C PDQNDVIQA+KAY+LQSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 494 bits (1272), Expect = e-138 Identities = 232/396 (58%), Positives = 303/396 (76%) Query: 3229 IMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQL 3288 ++ A N + S LY++ + K++GYD+R+DAI I AKASR+IAS+YKYKE YRKQL Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 3289 GHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLV 3348 GHH+G R + DDPK +W++H AK+QSDREYKK +EK K +++P+DM+ IV AKKCQ LV Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 3349 SDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAK 3408 SD+DY++ LH+W CLPDQND+I A+KAYDLQSDNLYKSDLEW+KGIGW+P S+EV+R K Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 3409 RAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPD 3468 A LL++ +YR +PE LKFTSI DTPE + AK NA+ +++ LY AW+ +K ++V D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 3469 TPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYR 3528 TP ++ +K+N + S+K Y+ A E+ K GYDLR DAI IQ AKASRDIASDY YK Y Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 3529 KQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQ 3588 KQ GH+IG R+ K+DPK++W+ +V K+Q+DR YKK + K K S PVDM+ + AK+ Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 3589 ILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSD 3624 L SD+DY+H LH W+C PDQNDVIQARKAYDLQSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 483 bits (1244), Expect = e-135 Identities = 223/396 (56%), Positives = 301/396 (76%) Query: 2986 IMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQL 3045 ++ A N + S LY+ + K+KGYD+R+DAI I AKASR++ S+YKYK+GYRKQL Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 3046 GHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 3105 GHH+G R ++DDPK +W++H AKIQSDREYKK +EK K ++P+DM+ +V AKKCQ LV Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 3106 SDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCK 3165 SD+DY+NYLH+WTCLPDQNDVI A++AYDLQSDN+YKSDL+WL+GIGW+P GS++V++ K Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 3166 RAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPD 3225 A +L++ +YR P+ LKFTS+ D+ E + AK NA+ +++ LY AW+K+K V++ D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 3226 TPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYR 3285 TP ++ ++ N + S Y+QA E+ K GYDLR+DAI I AKASRDIASDY YK AY Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 3286 KQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQ 3345 KQ GH+IG R+ +DPK++W+ ++ K+Q+DR YKK + +K + S PVDM+ I AK+ Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 3346 TLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSD 3381 L SDVDY+H LH W C PDQND+I ARKAYDLQSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 478 bits (1231), Expect = e-134 Identities = 223/393 (56%), Positives = 298/393 (75%) Query: 2503 AKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHH 2562 A N + S+KLY+ + + K+KGYD+ DAI IK AKASREIASEYKYKEG+RKQLGHH Sbjct: 4 AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHH 63 Query: 2563 IGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDV 2622 +G R ++DDPK +W++H AKIQSDREYKK +EK K ++P+DM+ +V AKKCQ LVSD+ Sbjct: 64 MGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDI 123 Query: 2623 DYKNYLHQWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRAT 2682 DY+NYLHQWTCLPDQ+DVI A++AYDLQSDNLYKSDL+WLKGIGW+ GS+E + K A Sbjct: 124 DYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183 Query: 2683 QILSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPE 2742 +L++ +YR P+ KF+S++D+ ++ AK NA+ ++ LY AW+K+K V++ DTP Sbjct: 184 NLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPL 243 Query: 2743 VLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQL 2802 +L +K N + S K Y+ E+ K GYD+R DAI I+ AKASRDIAS++ YK Y KQ Sbjct: 244 MLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQK 303 Query: 2803 GHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 2862 GH+IG R+ ++DPK++W+ +V K+Q+DR YKK + K K S PVDM+ + AK+ Q L Sbjct: 304 GHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALA 363 Query: 2863 SDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSD 2895 SDVDY++YLH W+C PDQ+DVI AR+AYDLQSD Sbjct: 364 SDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 478 bits (1230), Expect = e-134 Identities = 222/396 (56%), Positives = 300/396 (75%) Query: 2743 VLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQL 2802 +L A N + S KLY+ + K+KGYD+R DAI IK AKASR+IASE+KYKEGYRKQL Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 2803 GHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 2862 GHH+G R ++DDPK +W++H AKIQSDREYKK +EK K ++P+DM+ +V AKKCQ LV Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 2863 SDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCK 2922 SD+DY+NYLHQWTCLPDQ+DVI A++AYDLQSDN+YKSDL+W++GIGW+ GS++V + K Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 2923 RATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPD 2982 A +L++++YR P+ KFTS+ D+ E + AK NA+ +++ LY AW+K+K +++ D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 2983 TPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYR 3042 TP ++ ++ N + S Y+ A E+ K GYDLR+DAI I AKASRD+ SDY YK Y Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 3043 KQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQ 3102 KQ GH+IG R+ ++DPK++W+ +V K+Q+DR YKK + K K S PVDM+ + AK+ Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 3103 TLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSD 3138 L SDVDY++YLH W+C PDQNDVI AR+AYDLQSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 477 bits (1227), Expect = e-133 Identities = 223/396 (56%), Positives = 300/396 (75%) Query: 2257 ILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQL 2316 +LQA N S KLY+ W + +KGYD+ DAI ++ AKASR+IAS+YKYK+GYRKQL Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 2317 GHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELV 2376 GHH+GFR+LQDDPK V +++ AK+QS+REYKK +EK K ++P+DM+ +V AKKCQ LV Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 2377 SDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNK 2436 SD+DY+NYLHQWTCLPDQNDV+QAKK Y+LQS+NLYKSDLEWL+GIGW P GS+E + K Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 2437 RASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPD 2496 A +++E+ YR P+ KFTSI D +++ AK NA S+ LYR AW+K+K +++ D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 2497 TPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFR 2556 TP ++ +K N + S+K Y+ +E++K GYDL DAI I+ AKASR+IAS+Y YK + Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 2557 KQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQ 2616 KQ GH+IG R+ ++DPK++W+ +V K+Q+DR YKK + K K S PVDM+ + AK+ Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 2617 TLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSD 2652 L SDVDY++YLH W+C PDQ+DVI AR+AYDLQSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 420 bits (1079), Expect = e-116 Identities = 206/393 (52%), Positives = 275/393 (69%), Gaps = 2/393 (0%) Query: 3961 ARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHY 4019 A NAL +SNKLY++ W++ K G D+R DAI I+ AKASREIAS+YKYK + KQ GH+ Sbjct: 4 AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHH 63 Query: 4020 VGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDM 4079 +G T +DD K WA+ A K+Q++REY+ + K K +P+DM+SI+ +K Q LVSD+ Sbjct: 64 MGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDI 123 Query: 4080 DYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAA 4139 DYRNYLHQWTC+PDQNDVIQAKKAY+LQSDN+YK+DLEWL+GIGW+P SV V K+A Sbjct: 124 DYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183 Query: 4140 DIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTL-TETPL 4198 ++ +E+ YR K E L FT + D + + AK + + + YR W K+ + +TPL Sbjct: 184 NLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPL 243 Query: 4199 LHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQK 4258 + ++ A + Y++ WE K TGY L DA+ HA D+ S+ YK + KQK Sbjct: 244 MLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQK 303 Query: 4259 GHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLV 4318 GHY+G + ++DPKLVW + ++QN+RLYK+ Y+ KAKI+IP DMVS+ AAK+GQ L Sbjct: 304 GHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALA 363 Query: 4319 SDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSD 4351 SD+DYR+YLH W C PDQNDVIQARKAYDLQSD Sbjct: 364 SDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 392 bits (1006), Expect = e-108 Identities = 192/397 (48%), Positives = 269/397 (67%), Gaps = 1/397 (0%) Query: 2013 IILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGK 2072 ++ A NA+ +S+KLY+ ++K+KGYD+R DAI IK AKASR+IAS+YKYK Y K Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 2073 GKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANI 2132 G +GFR+L+DDPK V ++ AK+QSDREYKK YE +K ++TP DM+S+ AK Q + Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 2133 TNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKA 2192 ++ +Y++ +H++ LPD ++ + +QSDN YK D EW KG+GW P GS+EV + Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRV 179 Query: 2193 KKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMP 2252 K A +++ YR P +F + D+ +++ AK NA +++ LY W K+K ++V Sbjct: 180 KNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA 239 Query: 2253 DTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGY 2312 DTP +LQ+K N S K Y+ WE+ GYDL DAI +Q AKASRDIASDY YK Y Sbjct: 240 DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299 Query: 2313 RKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKC 2372 KQ GH++G RS ++DPKLV + NV KMQ++R YKK + K K S PVDM+ + AK+ Sbjct: 300 EKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEG 359 Query: 2373 QELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSE 2409 Q L SDVDY++YLH W+C PDQNDV+QA+K Y+LQS+ Sbjct: 360 QALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 380 bits (977), Expect = e-104 Identities = 195/396 (49%), Positives = 262/396 (66%), Gaps = 1/396 (0%) Query: 1526 IQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKG 1585 +QA +NAL +S+ Y+ DW T KGYD+R DAI I AK+SR IAS+ KYKE Y K G Sbjct: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 Query: 1586 KQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQEVAT 1645 +GF +LQDDPK V ++ AKIQSDREYKK YE SK ++TPLDM+S+ AKK Q + + Sbjct: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 Query: 1646 NANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKAK 1705 + +YR H +T LPD +V ++ A +QSDNLYKSD W+KGIGW+P S+EV + K Sbjct: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRVK 180 Query: 1706 KAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPD 1765 A +L+E+ YR PE LKFT +DT E K N + + + LY W K+K ++V D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 1766 TPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYE 1825 TP +L S++N + +S+K Y+ WE+ K GYDLR DAI I+ A+ASRDIASDY YK AYE Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 1826 QAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQ 1885 + KG +IG RS ++DPKLV V KMQ+DR YKK Y K PVDM+S+ AAK+ Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 1886 EVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSD 1921 +A++ +YR+ +H ++ PD A+ +QSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 379 bits (972), Expect = e-104 Identities = 195/396 (49%), Positives = 267/396 (67%), Gaps = 1/396 (0%) Query: 1038 IQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKG 1097 +QA +NA IS +Y+ D D +KGYD+R DAI I+ AKA+R+ AS+ +YK+ Y K G Sbjct: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 Query: 1098 KMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVS 1157 +GF++LQDDPK V ++ AKIQSDREYKK YEK+K +NTP DM ++V AKK Q +VS Sbjct: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 Query: 1158 NVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVK 1217 +++Y++ LH +T LPD D+ +K +QSDN+YK D W+KGIGW+P GS++V +VK Sbjct: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180 Query: 1218 KAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPD 1277 A + LNE+ YR P+ LKFTSIVD+P ++QAK N Q+S+ LY+ E K + D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 1278 LPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYE 1337 P LQ+K NA IS+ Y++ W D+ G ++ DAI I AKASR+IASDY YK AYE Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 1338 KSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQ 1397 K KG ++G RS ++DPKLV NV K+Q+DR YKK Y + K P DMVSI+AAK Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 1398 DVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSD 1433 +A++V+Y+ LHH++ PD + R +QSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 377 bits (967), Expect = e-103 Identities = 186/397 (46%), Positives = 272/397 (68%), Gaps = 1/397 (0%) Query: 1769 ILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAK 1828 +L + +N + +S+KLY+ W + K+KGYD+R DAI IK A+ASR+IAS+YKYK+ Y + Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 1829 GKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVA 1888 G H+GFR+L+DDPK V + AK+QSDREYKK YEKSK +TP+DM+S+V AKK Q + Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 1889 TNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKN 1948 ++ +YRN +H + LPD AK +QSDN YK+D +++KGIGWLP GS+E + Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRV 179 Query: 1949 KKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP 2008 K A +++E+ YR P+ LK+++++D+ ++ A+ NA ++E LY+ AWE +K V++ Sbjct: 180 KNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA 239 Query: 2009 DIPQIILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNY 2068 D P ++ +K NA+ +S+K Y+ + E+ K GYDLR DAI I+ AKASRDIASDY YK Y Sbjct: 240 DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299 Query: 2069 EKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDA 2128 EK KG +G RS ++DPKLV + V KMQ+DR YKK Y + K P DM+S++AAK+ Sbjct: 300 EKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEG 359 Query: 2129 QANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSD 2165 QA ++ +Y+H +H + PD ++ R +QSD Sbjct: 360 QALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 362 bits (929), Expect = 7e-99 Identities = 188/396 (47%), Positives = 260/396 (65%), Gaps = 1/396 (0%) Query: 1282 LQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKG 1341 LQA NA IS+ Y++DW+D KG ++ DAI I AKASR IAS+YKYKE Y K G Sbjct: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 Query: 1342 KHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVAT 1401 H+GFR+LQDDPK V ++ AK+QSDREYKK YE +K ++TP DM+SI AK Q + + Sbjct: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 Query: 1402 NVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVK 1461 +++Y+ LH +T LPD + + +QSDN+YK + +LKGIGW+P GS+EV +VK Sbjct: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180 Query: 1462 KAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPE 1521 A + LNER YR P+ +KFTS+ D+ ++ A+ N Q+S+ Y+ EK K + + Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 1522 LPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYE 1581 P +Q+K+NAL +S+ Y+ W+ GYDLR DAI I AK+SR+IASD YK AYE Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 1582 KAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQ 1641 K KG +G S ++DPKLV NV K+Q+DR YKK Y K K P+DMVS++AAK+ Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 1642 EVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSD 1677 +A++ +YR HH++ PD +V +R A +QSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 355 bits (912), Expect = 6e-97 Identities = 180/396 (45%), Positives = 257/396 (64%), Gaps = 1/396 (0%) Query: 794 IQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKG 853 +Q +NA +S+ +Y++DW +K K +DI+ DAI + AKA+ + S+ YK+ Y K G Sbjct: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 Query: 854 KMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIAS 913 +G ++ DDPK + ++ AK QSDREY+K YEKSK I+ PLDM+ + QAKK Q + S Sbjct: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 Query: 914 DVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAK 973 D+DY++ LH ++ PD +V AKKAY LQSD YK+D W+KG GW+P GS+E+ + K Sbjct: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180 Query: 974 RASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPD 1033 A ++LNE+ YR P+ LKFTSI D P +Q+KIN Q S+ Y+ E+ N+P D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 1034 LPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYE 1093 P +Q+K+NA IS Y+ +D+ GYDLR DAI I+ AKA+R ASD YK YE Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 1094 KAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQ 1153 K KG +G +S ++DPKLV NV K+Q+DR YKK Y K+K + P DM ++ AAK+ Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 1154 DVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSD 1189 + S+V+Y+H LHH++ PD D+ ++ +QSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 332 bits (850), Expect = 1e-89 Identities = 174/386 (45%), Positives = 239/386 (61%), Gaps = 6/386 (1%) Query: 4213 LYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPK 4272 LY++ W K GY + DA+ HA ++ SE KYK + KQ GH++G T++DDPK Sbjct: 15 LYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPK 74 Query: 4273 LVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMC 4332 VW HA +IQ++R YK+ Y K+K N P DM+S++ AK+ Q LVSDIDYRNYLHQW C Sbjct: 75 SVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTC 134 Query: 4333 HPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKNQEMMSQIKY--K 4390 PDQNDVIQA+KAYDLQSDN+Y++DLEWL+GIGW+P SV+ +RV Q ++++ Y K Sbjct: 135 LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIK 194 Query: 4391 KNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDM 4450 AL+ F S+VD PE++ AKIN+V S+ Y+ + K K DTP + SK Sbjct: 195 PEALK----FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKIN 250 Query: 4451 GKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGK 4510 S Y+ AWE K GY L I I AK + + S+ YK YEKQKGHY+ + Sbjct: 251 ALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCR 310 Query: 4511 VIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRH 4570 E P +V + KM++ Y+K Y D KA + IP DM++ AK Q + SD++YRH Sbjct: 311 SAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYRH 370 Query: 4571 YFHQWTSLLEEPNVIRVRNAQEILSD 4596 Y H W+ ++ +VI+ R A ++ SD Sbjct: 371 YLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 261 bits (668), Expect = 1e-68 Identities = 142/400 (35%), Positives = 222/400 (55%), Gaps = 4/400 (1%) Query: 547 IQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKG 606 +Q +NA +S+ LY++DW +K K +DI+ DAI + AKA+ + S+ YK+ Y K G Sbjct: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 Query: 607 KMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSE 666 +G ++ DDPK + ++ AK QSDR YK+ YEK+K TP + + Sbjct: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTPLDMMSIVQAKKCQ 117 Query: 667 ARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEY 726 D+ ++ L + + K SD YK++ E KG + P+ + Sbjct: 118 VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVM 177 Query: 727 EAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHI 786 + + Y++ P+ KFT++ D+P ++QA++N Q+S+ Y+ E EK ++ Sbjct: 178 RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNV 237 Query: 787 PADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKK 846 PAD P +Q ++NA +S+ Y+Q WE K +D++ DAI + AKA+ SD +YK Sbjct: 238 PADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKT 297 Query: 847 DYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAK 906 YEK KG IG S +DPK++ + K Q+DR Y+K Y K + P+DM+ ++ AK Sbjct: 298 AYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAK 357 Query: 907 KSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDV 946 + QA+ASDVDY+H LH +S PD +V A+KAY LQSDV Sbjct: 358 EGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 Score = 241 bits (615), Expect = 2e-62 Identities = 136/388 (35%), Positives = 205/388 (52%), Gaps = 2/388 (0%) Query: 4455 STILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGE 4514 S LY+ W TK GY + I I AK + + SE KYKE Y KQ GH++ + + + Sbjct: 12 SNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQD 71 Query: 4515 FPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQ 4574 P V + K++S Y+K YE +K + P DMM+ V AK+CQ ++SD++YR+Y HQ Sbjct: 72 DPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ 131 Query: 4575 WTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQY 4634 WT L ++ +VI+ + A ++ SDN+YK DL WLKGIG + +++ K + +L ++ Y Sbjct: 132 WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLY 191 Query: 4635 TAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRN 4694 K + + DTP + A + + SE Y+ + + K +T +++ Sbjct: 192 RI--KPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKI 249 Query: 4695 LKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLP 4754 S+ Y++AW+ VK T Y L + + + HAK + +AS Y+ YEK K Y Sbjct: 250 NALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGC 309 Query: 4755 RSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYR 4814 RS +DP V K+ DRLY+ Y +K KI I DMV + AK+ Q S++DYR Sbjct: 310 RSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYR 369 Query: 4815 LRLHEWICHPDLQVNDHVRKVTDQISDI 4842 LH W C PD RK D SD+ Sbjct: 370 HYLHHWSCFPDQNDVIQARKAYDLQSDV 397 Score = 182 bits (461), Expect = 1e-44 Identities = 124/403 (30%), Positives = 190/403 (47%), Gaps = 14/403 (3%) Query: 4700 SSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDD 4759 S+ LY++ W+ K Y + + + + HAK + +AS KY+E Y K + R++ D Sbjct: 12 SNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQD 71 Query: 4760 DPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVP-DMVEMVTAKDSQKKVSEIDYRLRLH 4818 DP + + K+ DR Y+ YEK+K IH P DM+ +V AK Q VS+IDYR LH Sbjct: 72 DPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH 130 Query: 4819 EWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIK 4878 +W C PD +K D SD +YK DL WLKGIG + E++ K+A +L ++ Sbjct: 131 QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERL 190 Query: 4879 Y--KAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLD 4936 Y K LK + + DTP +QA + Q+S+ +Y + P + L Sbjct: 191 YRIKPEALK----FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQ 246 Query: 4937 RALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAY- 4995 ++A ++ + + TGY L D +H K +R ++S + YK AYE K + Sbjct: 247 SKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHY 306 Query: 4996 -GYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSEL 5054 G +D V V + ++RLY++ Y+ K KI D I K+ Q S++ Sbjct: 307 IGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDV 366 Query: 5055 IYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQV 5097 Y+ H P VI R D+ SD+ QV Sbjct: 367 DYRHYLH----HWSCFPDQNDVIQARKAYDLQSDVSVSPRKQV 405 Score = 177 bits (448), Expect = 4e-43 Identities = 110/346 (31%), Positives = 175/346 (50%), Gaps = 6/346 (1%) Query: 300 ARMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKA 359 A +NA IS + YQ+D+ + K + Y ++ + E K K + AS+ KYKE Y K G Sbjct: 4 AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH- 62 Query: 360 DYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSD 419 ++P+ A SD+ YK+ YEK+K TP + +++Q Sbjct: 63 HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTP-LDMMSIVQAKKCQ 117 Query: 420 KKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEY 479 D ++ L + + K SD YK++ E +G G+ P+ + Sbjct: 118 VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVM 177 Query: 480 EAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHI 539 + + Y++ P+ KFT + D+P ++QA++N+ Q+S+ Y+ E EK ++ Sbjct: 178 RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNV 237 Query: 540 PPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKK 599 P DTP +Q K+NA +S+ Y+Q WE K +D++ DAI + AKA+ SD +YK Sbjct: 238 PADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKT 297 Query: 600 DYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAK 645 YEK KG IG S +DPK++ + V K Q+DRLYK+ Y KAK Sbjct: 298 AYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAK 343 Score = 133 bits (335), Expect = 5e-30 Identities = 119/409 (29%), Positives = 183/409 (44%), Gaps = 30/409 (7%) Query: 4940 HAYKLQSSN-LYKTSLR-TLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGY 4997 H LQ SN LY+ T GY + D KH K +R ++S +KYKE Y K G+ Sbjct: 5 HINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYR--KQLGH 62 Query: 4998 TLG-------PKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTP-DTPEIRQVKKTQE 5049 +G PK V +H ++ S+R Y++ Y K K IH TP D I Q KK Q Sbjct: 63 HMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKG-IHNTPLDMMSIVQAKKCQV 118 Query: 5050 AVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTP 5109 VS++ Y++ + LP VI + D+ SD YK DL+ LKG G + Sbjct: 119 LVSDIDYRNYLHQWT----CLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSV 174 Query: 5110 DMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQK 5169 +++R ++ + L + LY K + K+ ++DTPE + + +SE +YR A +K+K Sbjct: 175 EVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEK 232 Query: 5170 SIFTSVPDTPDLLRAKRGQKLQSQYLYVEL-ATKERPHHHAGNQTTALKHAKDVKDMVSE 5228 + DTP +L++K S Y + + + ++HAK +D+ S+ Sbjct: 233 ANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASD 292 Query: 5229 KKYKIQYEKMKDKY---TPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALD 5285 YK YEK K Y + P L+ A +D YK+ + K K D + Sbjct: 293 YLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVS 352 Query: 5286 IVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDV 5334 I ++ S + Y+ L W PD+ + R D SDV Sbjct: 353 ISAAKEGQALASDVDYRH----YLHHWSCFPDQNDVIQARKAYDLQSDV 397 Score = 126 bits (317), Expect = 6e-28 Identities = 111/405 (27%), Positives = 164/405 (40%), Gaps = 86/405 (21%) Query: 5216 LKHAKDVKDMVSEKKYKIQYEKMKDK---YTPVPDTPILIRAKRAYWNASDLRYKETFQK 5272 +KHAK +++ SE KYK Y K + + D P + A A SD YK+ ++K Sbjct: 37 IKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 96 Query: 5273 TKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVS 5332 +KG ++T D + IV +K +S I Y+ NY+ Q W +PD+ + + D S Sbjct: 97 SKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYLHQ---WTCLPDQNDVIQAKKAYDLQS 152 Query: 5333 DVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINR 5392 D YK DL WLKGIG + + Sbjct: 153 DNLYKSDLEWLKGIGWLPEGSVEVM----------------------------------- 177 Query: 5393 HFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKF 5452 K A L+NE+ YR E K + +VD P + AK QIS+ YR +EK K Sbjct: 178 RVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANV 235 Query: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKY 5512 DTP L++ QIS+ Y+ + K GY D + H + +D SD Y Sbjct: 236 NVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLY 295 Query: 5513 KEVYQR--------------------------------------NKSNCTIEPDAVHIKA 5534 K Y++ +K+ +I D V I A Sbjct: 296 KTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISA 355 Query: 5535 AKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSD 5579 AK+ + +++DY+ HW PD+ D +QA K+ QSD Sbjct: 356 AKEGQALASDVDYRHYLH----HWSCFPDQNDVIQARKAYDLQSD 396 Score = 101 bits (252), Expect = 2e-20 Identities = 102/381 (26%), Positives = 175/381 (45%), Gaps = 30/381 (7%) Query: 5856 LNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPML 5915 +N Q+++ K + + Y D +E H K + E+ S KYKE Y K+ G M Sbjct: 6 INALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHM- 64 Query: 5916 DFET----PTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASE 5971 F T P + A + ++QS +EY+K YE+S KG + T L++ +++ K + S+ Sbjct: 65 GFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKS-KGIHNTPLDMM-SIVQAKKCQVLVSD 122 Query: 5972 KEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANET 6031 +YR L + T + D D+++AK A + ++ YK DLE +G+ + + Sbjct: 123 IDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWL---KGIGWLPEGS 173 Query: 6032 PDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKS 6091 + MR +NA ++ ++ Y+ E K FTS+VDTPE+I A+ S+ Y+ EK Sbjct: 174 VEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKE 231 Query: 6092 MSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSK-GKITVVQDTPEILRVKENQKNFS 6150 + DTP + + + N S +YQ ++ K + D I K ++ S Sbjct: 232 KANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIAS 291 Query: 6151 SVLYKE--DVSPGTAIG-----KTPEMM----RVKQTQDHISSVKYKEAIGQGTPIPDLP 6199 LYK + G IG + P+++ +K D + Y + + + D+ Sbjct: 292 DYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMV 351 Query: 6200 EVKRVKETQKHISSVMYKENL 6220 + KE Q S V Y+ L Sbjct: 352 SISAAKEGQALASDVDYRHYL 372 Score = 95.5 bits (236), Expect = 2e-18 Identities = 91/376 (24%), Positives = 173/376 (46%), Gaps = 28/376 (7%) Query: 5470 QISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSN----CTI 5525 QIS+ LY+ ++N K +GY D + H + ++ S+ KYKE Y++ + T+ Sbjct: 10 QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69 Query: 5526 EPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLD 5585 + D + A A K+ ++ +YKK YE +K D +QA K + SD +Y Sbjct: 70 QDDPKSVWAI-HAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY--- 125 Query: 5586 REFLKGCKLSVTDDKNTVLALRNTL-IESDLKYKEKHVKERGTCHAVPDTPQILLAKTVS 5644 R +L + + D+N V+ + ++SD YK +G + +++ K Sbjct: 126 RNYLH--QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183 Query: 5645 NLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSI 5704 NL++E Y+ +K + +T++ +T + + K +S+ Y+ + EK K+N ++ Sbjct: 184 NLLNERLYR--IKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAW--EKEKANVNV 237 Query: 5705 MLEPPEVK----HAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEY 5760 + P + +A++++ K+ A+ +D K Y AD I+ A + AS+ Y Sbjct: 238 PADTPLMLQSKINALQISNKRYQQAW-EDVKMT-GYDLRADAIGIQHAKASRDIASDYLY 295 Query: 5761 RAKHRKEGSHGL---SMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLY 5817 + + K+ H + S P + A K+ + Y++ ++ K K P D Sbjct: 296 KTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKIS--IPVDMVSI 353 Query: 5818 KVMKDANNLASEVKYK 5833 K+ LAS+V Y+ Sbjct: 354 SAAKEGQALASDVDYR 369 Score = 91.7 bits (226), Expect = 2e-17 Identities = 105/408 (25%), Positives = 171/408 (41%), Gaps = 29/408 (7%) Query: 5397 ATQLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK---F 5452 A Q+ N K Y+ D+ K K Y + D AK + + S+ KY++ Y K F Sbjct: 8 ALQISN-KLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGF 66 Query: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPM----LLHVRKVKDEVS 5508 ++ D P+ + K SD YK Y K+K IH+TP+ ++ +K + VS Sbjct: 67 RTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-----GIHNTPLDMMSIVQAKKCQVLVS 121 Query: 5509 DLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPD-RPDF 5567 D+ Y+ + T PD + AK AY + ++ YK E K W P+ + Sbjct: 122 DIDYRNYLHQ----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-IGWLPEGSVEV 176 Query: 5568 LQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGT 5627 ++ + ++ Y++ E LK S+ D + A N + S+ Y+ KE+ Sbjct: 177 MRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKAN 234 Query: 5628 CHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT 5687 + DTP +L +K ++ L NK + + Y + H K SD Sbjct: 235 VNVPADTPLMLQSK-INALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDY 293 Query: 5688 NYKKKFVKEKGK-SNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTV-ADRPDI 5745 YK + K+KG E P++ A V K Q+D Y+K ++ ++ D I Sbjct: 294 LYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSI 353 Query: 5746 KKATQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQV 5793 A + AS+V+YR H + D+ A+KA L S V Sbjct: 354 SAAKEGQALASDVDYRHYLH----HWSCFPDQNDVIQARKAYDLQSDV 397 Score = 91.7 bits (226), Expect = 2e-17 Identities = 84/315 (26%), Positives = 143/315 (45%), Gaps = 11/315 (3%) Query: 86 IAHSQKMQDLFSPNKYKEKFEKTKGQPYASTT---DTPELRRIKKVQDQLSEVKYRMDGD 142 I H++ +++ S KYKE + K G T D + I + Q S+ +Y+ + Sbjct: 37 IKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ-SDREYKKAYE 95 Query: 143 VAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMF 202 +K I + I AKK VS + Y+ ++ PD +++QA K + Sbjct: 96 KSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQ 151 Query: 203 SKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDI 262 S LY D E K + + S E+ RV AQ L++ Y+ + + +FT + D P++ Sbjct: 152 SDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEV 209 Query: 263 EFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQ 322 AK Q+S+ Y+ +E + + +++NA IS ++YQ+ +E++K Sbjct: 210 IQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMT 269 Query: 323 IYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDAL 382 Y ++ + + K + AS YK YEK KG A E+P+L Sbjct: 270 GYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHY-IGCRSAKEDPKLVWAANVLKMQ 328 Query: 383 SDKLYKENYEKTKAK 397 +D+LYK+ Y KAK Sbjct: 329 NDRLYKKAYNDHKAK 343 Score = 84.3 bits (207), Expect = 4e-15 Identities = 95/414 (22%), Positives = 167/414 (40%), Gaps = 53/414 (12%) Query: 5532 IKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKG 5591 ++A +A +++ L K + + + D + A S S+++YK G Sbjct: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 Query: 5592 CKL---SVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVS 5648 + ++ DD +V A+ I+SD +YK+ + K +G + D I+ AK LVS Sbjct: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 Query: 5649 ENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEP 5708 + Y++++ + +T LP+ D + K+ SD YK KG I P Sbjct: 122 DIDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-----IGWLP 170 Query: 5709 PEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEG 5768 M V K+A+ L+ +P+ K T Sbjct: 171 EGSVEVMRV----------KNAQNLLNERLYRIKPEALKFT------------------- 201 Query: 5769 SHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLAS 5828 S++ P++ AK A S+ YR ++KEK P D+ L K S Sbjct: 202 ----SIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNV--PADTPLMLQSKINALQIS 255 Query: 5829 EVKYKADLKKLHKPVTDMKESLI-MNHVLNTSQLASSYQYKKKYEKSKGHY---HTIPDN 5884 +Y+ + + D++ I + H + +AS Y YK YEK KGHY + ++ Sbjct: 256 NKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKED 315 Query: 5885 LEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYR 5938 + + ++Q+ YK+ Y + K + + + AKE Q + S +YR Sbjct: 316 PKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYR 369 Score = 79.0 bits (193), Expect = 2e-13 Identities = 91/349 (26%), Positives = 140/349 (40%), Gaps = 53/349 (15%) Query: 166 QVSKVLYKQNWEDTKDK-YLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSL-----FY 219 Q+S LY+++W DTK K Y + DA E+ A + + S+ Y E + K L F Sbjct: 10 QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYR--KQLGHHMGFR 67 Query: 220 PYNDSPELRRVAQAQKALSDVAYKKGLAEQQA---------------------------- 251 D P+ A K SD YKK + + Sbjct: 68 TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN 127 Query: 252 ---QFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKG-KWSETPCFEVANARMNADNI 307 Q+T L D D+ AKK + S YK D E +KG W EV + + + Sbjct: 128 YLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVKNAQNLL 186 Query: 308 STRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPAS 367 + R Y+ E +K + +TPE K V S+ Y+ +EK K NV + Sbjct: 187 NERLYRIKPEALK---FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKA----NVNVPA 239 Query: 368 ENPQLRQLKAAGDALSDKLYKENYEKTKAKSINY-CETPKFKLDTVLQNFSSDKKYKDSY 426 + P + Q K +S+K Y++ +E K + + + ++ +SD YK +Y Sbjct: 240 DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299 Query: 427 LKDILGHYVG---SFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFP 472 K GHY+G + EDP V +D+ YK Y + + K P Sbjct: 300 EKQ-KGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIP 347 Score = 68.9 bits (167), Expect = 2e-10 Identities = 96/386 (24%), Positives = 156/386 (40%), Gaps = 32/386 (8%) Query: 192 LVQAVKNTAMFSKKLYTEDWEADKSLFYPYN-DSPELRRVAQAQKALSDVAYKKGLAEQQ 250 ++QA N S KLY +DW K Y D+ E++ +++ S+ YK+G +Q Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 251 AQ---FTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETP-----CFEVANARM 302 F L D P +A S ++YK+ YE K KG TP + ++ Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYE-KSKG-IHNTPLDMMSIVQAKKCQV 118 Query: 303 NADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYN 362 +I R Y + + DQ +Q KKA S YK D E KG Sbjct: 119 LVSDIDYRNYLHQWTCLPDQNDVIQA--------KKAYDLQSDNLYKSDLEWLKG---IG 167 Query: 363 VLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKY 422 LP + ++ ++K A + L+++LY+ E K SI +TP+ + S+ Y Sbjct: 168 WLPEG-SVEVMRVKNAQNLLNERLYRIKPEALKFTSI--VDTPEVIQAKINAVQISEPLY 224 Query: 423 KDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAI 482 ++++ K+ V + + P Q S+K Y+ +E+ + G+ + + Sbjct: 225 RNAWEKEKANVNVPA-DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHA 283 Query: 483 K-KLDQCKDHTYKVHPDKTK-----FTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFK 536 K D D+ YK +K K + P L+ A K +D YK + K K Sbjct: 284 KASRDIASDYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAK 343 Query: 537 CHIPPDTPAFIQHKVNAYNLSDNLYK 562 IP D + K SD Y+ Sbjct: 344 ISIPVDMVSISAAKEGQALASDVDYR 369 Score = 40.0 bits (92), Expect = 0.078 Identities = 52/226 (23%), Positives = 91/226 (40%), Gaps = 14/226 (6%) Query: 6262 EMERVKRNQENFSSVLYKE--------NMGKGTPLAVTPEMERVKHNQENISSVLYKENV 6313 E++ K ++E S YKE +MG T L P+ H + S YK+ Sbjct: 36 EIKHAKASREIASEYKYKEGYRKQLGHHMGFRT-LQDDPKSVWAIHAAKIQSDREYKKAY 94 Query: 6314 GKATATPVTP----EMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVKRNQENFSSV 6369 K+ TP + + K+ Q +S + Y+ L + T P ++ + K+ + S Sbjct: 95 EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDN 154 Query: 6370 LYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQG-KAAYVLDTPEMRRVRE 6428 LYK ++ PE +N ++L +R + + K ++DTPE+ + + Sbjct: 155 LYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKI 214 Query: 6429 TQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYR 6474 IS Y +EK K P+ + K N S+ Y+ Sbjct: 215 NAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQ 260 Score = 34.7 bits (78), Expect = 3.3 Identities = 37/162 (22%), Positives = 64/162 (39%), Gaps = 10/162 (6%) Query: 83 TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGD 142 TP + S+ S +Y++ +E K Y D ++ K +D S+ Y+ + Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 143 VAKTI---CHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNT 199 K C ++ + A V + + LYK+ + D K K +P D + A + Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 200 AMFSK---KLYTEDWEADKSLFYPYNDSPELRRVAQAQKALS 238 A+ S + Y W S F ND + R+ Q +S Sbjct: 361 ALASDVDYRHYLHHW----SCFPDQNDVIQARKAYDLQSDVS 398 >gi|239752495 PREDICTED: similar to nebulin [Homo sapiens] Length = 237 Score = 253 bits (647), Expect = 3e-66 Identities = 121/198 (61%), Positives = 151/198 (76%), Gaps = 12/198 (6%) Query: 3495 KKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAK 3554 K YDL L +P YKYKEGYRKQLGHH+G R ++DDPK +W+IH AK Sbjct: 9 KPHTYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAK 56 Query: 3555 IQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQ 3614 IQSDREYKK +EK K ++P+DM+ +V AKKCQ+LVSDIDY++ LH+WTCLPDQNDVIQ Sbjct: 57 IQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQ 116 Query: 3615 ARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCI 3674 A+KAYDLQSD +YKSDLEWL+GIGW+P GSVEV +VK A +L++R YR + LKFT I Sbjct: 117 AKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI 176 Query: 3675 TDTPEIVLAKNNALTMSK 3692 DTPE++ AK NA+ +S+ Sbjct: 177 VDTPEVIQAKINAVQISE 194 Score = 249 bits (635), Expect = 8e-65 Identities = 115/171 (67%), Positives = 143/171 (83%) Query: 3764 YKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLS 3823 YKYKE Y KQ GHH+G ++++DDPK + AIHA KIQS+REYKK ++K K ++P+DM+S Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 3824 ILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWM 3883 I+ AKKCQ LV+DIDYRNYLH+WTC+PDQND+IQAKKAYDLQSD LYK+DLEWL+GIGW+ Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142 Query: 3884 PQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENIS 3934 P+GS EV+RVKNAQN+ + +YR LK+TSIVDTPEV+ AK NA IS Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQIS 193 Score = 248 bits (632), Expect = 2e-64 Identities = 116/198 (58%), Positives = 148/198 (74%), Gaps = 12/198 (6%) Query: 3252 KKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAK 3311 K YDL +P YKYKE YRKQLGHH+G R + DDPK +W++H AK Sbjct: 9 KPHTYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAK 56 Query: 3312 VQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIH 3371 +QSDREYKK +EK K +++P+DM+ IV AKKCQ LVSD+DY++ LH+W CLPDQND+I Sbjct: 57 IQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQ 116 Query: 3372 ARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSI 3431 A+KAYDLQSDNLYKSDLEW+KGIGW+P S+EV+R K A LL++ +YR +PE LKFTSI Sbjct: 117 AKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI 176 Query: 3432 TDTPEQVLAKNNALNMNK 3449 DTPE + AK NA+ +++ Sbjct: 177 VDTPEVIQAKINAVQISE 194 Score = 245 bits (626), Expect = 9e-64 Identities = 106/175 (60%), Positives = 145/175 (82%) Query: 3032 ISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVD 3091 + YKYK+GYRKQLGHH+G R ++DDPK +W++H AKIQSDREYKK +EK K ++P+D Sbjct: 20 VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79 Query: 3092 MLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGI 3151 M+ +V AKKCQ LVSD+DY+NYLH+WTCLPDQNDVI A++AYDLQSDN+YKSDL+WL+GI Sbjct: 80 MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139 Query: 3152 GWVPIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNK 3206 GW+P GS++V++ K A +L++ +YR P+ LKFTS+ D+ E + AK NA+ +++ Sbjct: 140 GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194 Score = 237 bits (605), Expect = 3e-61 Identities = 103/172 (59%), Positives = 142/172 (82%) Query: 2792 FKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLG 2851 +KYKEGYRKQLGHH+G R ++DDPK +W++H AKIQSDREYKK +EK K ++P+DM+ Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 2852 VVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWV 2911 +V AKKCQ LVSD+DY+NYLHQWTCLPDQ+DVI A++AYDLQSDN+YKSDL+W++GIGW+ Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142 Query: 2912 SIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNK 2963 GS++V + K A +L++++YR P+ KFTS+ D+ E + AK NA+ +++ Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194 Score = 236 bits (603), Expect = 4e-61 Identities = 108/193 (55%), Positives = 146/193 (75%), Gaps = 12/193 (6%) Query: 2527 YDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSD 2586 YDL + +P YKYKEG+RKQLGHH+G R ++DDPK +W++H AKIQSD Sbjct: 13 YDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60 Query: 2587 REYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQA 2646 REYKK +EK K ++P+DM+ +V AKKCQ LVSD+DY+NYLHQWTCLPDQ+DVI A++A Sbjct: 61 REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA 120 Query: 2647 YDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSI 2706 YDLQSDNLYKSDL+WLKGIGW+ GS+E + K A +L++ +YR P+ KF+S++D+ Sbjct: 121 YDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTP 180 Query: 2707 PMVLAKNNAITMN 2719 ++ AK NA+ ++ Sbjct: 181 EVIQAKINAVQIS 193 Score = 236 bits (602), Expect = 6e-61 Identities = 108/172 (62%), Positives = 139/172 (80%) Query: 2306 YKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLG 2365 YKYK+GYRKQLGHH+GFR+LQDDPK V +++ AK+QS+REYKK +EK K ++P+DM+ Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 2366 VVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWS 2425 +V AKKCQ LVSD+DY+NYLHQWTCLPDQNDV+QAKK Y+LQS+NLYKSDLEWL+GIGW Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142 Query: 2426 PLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSD 2477 P GS+E + K A +++E+ YR P+ KFTSI D +++ AK NA S+ Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194 Score = 204 bits (518), Expect = 3e-51 Identities = 102/184 (55%), Positives = 136/184 (73%), Gaps = 7/184 (3%) Query: 4249 KYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSV 4308 KYK + KQ GH++G T++DDPK VW HA +IQ++R YK+ Y K+K N P DM+S+ Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 4309 LAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIP 4368 + AK+ Q LVSDIDYRNYLHQW C PDQNDVIQA+KAYDLQSDN+Y++DLEWL+GIGW+P Sbjct: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143 Query: 4369 LDSVDHVRVTKNQEMMSQIKY--KKNALENYPNFRSVVDPPEIVLAKINSVNQSDV-KYK 4425 SV+ +RV Q ++++ Y K AL+ F S+VD PE++ AKIN+V S+V K + Sbjct: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQISEVEKSR 199 Query: 4426 ETFN 4429 + FN Sbjct: 200 DNFN 203 Score = 198 bits (504), Expect = 1e-49 Identities = 92/178 (51%), Positives = 128/178 (71%) Query: 4006 YKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLS 4065 YKYK + KQ GH++G T +DD K WA+ A K+Q++REY+ + K K +P+DM+S Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 4066 ILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWM 4125 I+ +K Q LVSD+DYRNYLHQWTC+PDQNDVIQAKKAY+LQSDN+YK+DLEWL+GIGW+ Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142 Query: 4126 PNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKD 4183 P SV V K+A ++ +E+ YR K E L FT + D + + AK + + +++ +D Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200 Score = 189 bits (481), Expect = 6e-47 Identities = 93/184 (50%), Positives = 131/184 (71%), Gaps = 1/184 (0%) Query: 1087 QYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNV 1146 +YK+ Y K G +GF++LQDDPK V ++ AKIQSDREYKK YEK+K +NTP DM ++ Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 1147 VAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWI 1206 V AKK Q +VS+++Y++ LH +T LPD D+ +K +QSDN+YK D W+KGIGW+ Sbjct: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWL 142 Query: 1207 PIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGE 1266 P GS++V +VK A + LNE+ YR P+ LKFTSIVD+P ++QAK N Q+S++ Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNF 202 Query: 1267 DVKH 1270 +V+H Sbjct: 203 NVRH 206 Score = 176 bits (446), Expect = 7e-43 Identities = 86/172 (50%), Positives = 118/172 (68%), Gaps = 1/172 (0%) Query: 844 YKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVT 903 YK+ Y K G +G ++ DDPK + ++ AK QSDREY+K YEKSK I+ PLDM+ + Sbjct: 25 YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIV 84 Query: 904 QAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVP 963 QAKK Q + SD+DY++ LH ++ PD +V AKKAY LQSD YK+D W+KG GW+P Sbjct: 85 QAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLP 143 Query: 964 FGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDI 1015 GS+E+ + K A ++LNE+ YR P+ LKFTSI D P +Q+KIN Q S++ Sbjct: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195 Score = 172 bits (437), Expect = 8e-42 Identities = 85/185 (45%), Positives = 124/185 (67%), Gaps = 1/185 (0%) Query: 1330 YKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVS 1389 YKYKE Y K G H+GFR+LQDDPK V ++ AK+QSDREYKK YE +K ++TP DM+S Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 1390 ITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGW 1449 I AK Q + ++++Y+ LH +T LPD + + +QSDN+YK + +LKGIGW Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGW 141 Query: 1450 IPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEG 1509 +P GS+EV +VK A + LNER YR P+ +KFTS+ D+ ++ A+ N Q+S++ + Sbjct: 142 LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDN 201 Query: 1510 EKLKH 1514 ++H Sbjct: 202 FNVRH 206 Score = 167 bits (424), Expect = 2e-40 Identities = 86/172 (50%), Positives = 114/172 (66%), Gaps = 1/172 (0%) Query: 1575 KYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSV 1634 KYKE Y K G +GF +LQDDPK V ++ AKIQSDREYKK YE SK ++TPLDM+S+ Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 1635 TAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWV 1694 AKK Q + ++ +YR H +T LPD +V ++ A +QSDNLYKSD W+KGIGW+ Sbjct: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWL 142 Query: 1695 PIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDK 1746 P S+EV + K A +L+E+ YR PE LKFT +DT E K N + + + Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194 Score = 166 bits (421), Expect = 6e-40 Identities = 80/173 (46%), Positives = 120/173 (69%), Gaps = 1/173 (0%) Query: 1818 YKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLS 1877 YKYK+ Y + G H+GFR+L+DDPK V + AK+QSDREYKK YEKSK +TP+DM+S Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 1878 VVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGW 1937 +V AKK Q + ++ +YRN +H + LPD AK +QSDN YK+D +++KGIGW Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSD-LEWLKGIGW 141 Query: 1938 LPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNE 1990 LP GS+E + K A +++E+ YR P+ LK+++++D+ ++ A+ NA ++E Sbjct: 142 LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194 Score = 148 bits (374), Expect = 2e-34 Identities = 71/168 (42%), Positives = 107/168 (63%), Gaps = 1/168 (0%) Query: 2062 YKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLS 2121 YKYK Y K G +GFR+L+DDPK V ++ AK+QSDREYKK YE +K ++TP DM+S Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 2122 VTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGW 2181 + AK Q +++ +Y++ +H++ LPD ++ + +QSDN YK D EW KG+GW Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGW 141 Query: 2182 SPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNA 2229 P GS+EV + K A +++ YR P +F + D+ +++ AK NA Sbjct: 142 LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINA 189 Score = 129 bits (325), Expect = 7e-29 Identities = 66/182 (36%), Positives = 109/182 (59%), Gaps = 3/182 (1%) Query: 4494 KYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNH 4553 KYKE Y KQ GH++ + + + P V + K++S Y+K YE +K + P DMM+ Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 4554 VLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYV 4613 V AK+CQ ++SD++YR+Y HQWT L ++ +VI+ + A ++ SDN+YK DL WLKGIG Sbjct: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143 Query: 4614 WDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEV-KYKEN 4672 + +++ K + +L ++ Y K + + DTP + A + + SEV K ++N Sbjct: 144 EGSVEVMRVKNAQNLLNERLYRI--KPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDN 201 Query: 4673 YH 4674 ++ Sbjct: 202 FN 203 Score = 107 bits (268), Expect = 3e-22 Identities = 67/176 (38%), Positives = 95/176 (53%), Gaps = 8/176 (4%) Query: 4739 KYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVP-DMVE 4797 KY+E Y K + R++ DDP + + K+ DR Y+ YEK+K IH P DM+ Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMS 82 Query: 4798 MVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCY 4857 +V AK Q VS+IDYR LH+W C PD +K D SD +YK DL WLKGIG Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142 Query: 4858 VWDTPEILHAKHAYDLRDDIKY--KAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSD 4911 + E++ K+A +L ++ Y K LK + + DTP +QA + Q+S+ Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQISE 194 Score = 81.6 bits (200), Expect = 2e-14 Identities = 50/188 (26%), Positives = 88/188 (46%), Gaps = 9/188 (4%) Query: 597 YKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQ 656 YK+ Y K G +G ++ DDPK + ++ AK QSDR YK+ YEK+K TP Sbjct: 25 YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK----GIHNTPLDM 80 Query: 657 LDTQLKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKC 716 + + D+ ++ L + + K SD YK++ E KG Sbjct: 81 MSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140 Query: 717 YFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDL----- 771 + P+ + + + Y++ P+ KFT++ D+P ++QA++N Q+S++ Sbjct: 141 WLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200 Query: 772 NYKAKHEG 779 N+ +H G Sbjct: 201 NFNVRHYG 208 Score = 73.2 bits (178), Expect = 8e-12 Identities = 58/185 (31%), Positives = 91/185 (49%), Gaps = 20/185 (10%) Query: 4983 FKYKEAYEHTKAYGYTLG-------PKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTT 5035 +KYKE Y K G+ +G PK V +H ++ S+R Y++ Y K K IH T Sbjct: 23 YKYKEGYR--KQLGHHMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKG-IHNT 76 Query: 5036 P-DTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKED 5094 P D I Q KK Q VS++ Y++ + LP VI + D+ SD YK D Sbjct: 77 PLDMMSIVQAKKCQVLVSDIDYRNYLHQWT----CLPDQNDVIQAKKAYDLQSDNLYKSD 132 Query: 5095 LQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKT 5154 L+ LKG G + +++R ++ + L + LY K + K+ ++DTPE + + Sbjct: 133 LEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAV 190 Query: 5155 HLSEL 5159 +SE+ Sbjct: 191 QISEV 195 Score = 72.4 bits (176), Expect = 1e-11 Identities = 66/230 (28%), Positives = 94/230 (40%), Gaps = 50/230 (21%) Query: 5226 VSEKKYKIQYEKMKDK---YTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKD 5282 V KYK Y K + + D P + A A SD YK+ ++K+KG ++T D Sbjct: 20 VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79 Query: 5283 ALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTW 5342 + IV +K +S I Y+ NY+ Q W +PD+ + + D SD YK DL W Sbjct: 80 MMSIVQAKKCQVLVSDIDYR-NYLHQ---WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEW 135 Query: 5343 LKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMN 5402 LKGIG + + K A L+N Sbjct: 136 LKGIGWLPEGSVEV-----------------------------------MRVKNAQNLLN 160 Query: 5403 EKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKF 5452 E+ YR E K+ +VD P + AK QIS++ EKS+D F Sbjct: 161 ERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQISEV------EKSRDNF 202 Score = 69.7 bits (169), Expect = 9e-11 Identities = 63/231 (27%), Positives = 113/231 (48%), Gaps = 23/231 (9%) Query: 5864 SYQYKKKYEKSKGH---YHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETP 5920 SY+YK+ Y K GH + T+ D+ + + A ++QS +YK+ YEK +G + Sbjct: 22 SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMM 81 Query: 5921 TYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEE 5980 + + AK+ Q + S +YR + T L ++ K A + S+ Y+ DL E Sbjct: 82 SIVQAKKCQVLVSDIDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDL-E 134 Query: 5981 SIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLN-AMANETPDFMRAR- 6038 ++G G E + +++R KNA +LNE+ Y+ +K L +TP+ ++A+ Sbjct: 135 WLKGIGWLP-EGSVEVMRVKNAQNLLNERLYR------IKPEALKFTSIVDTPEVIQAKI 187 Query: 6039 NATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQ--VKNLSSQKKYKED 6087 NA I+ K + + + ++ S +D ++ AQQ + LS+ Y D Sbjct: 188 NAVQISEVEKSRDNFNVR--HYGSYLDQKQLGPAQQWELSELSAMWTYPSD 236 Score = 60.5 bits (145), Expect = 6e-08 Identities = 54/191 (28%), Positives = 88/191 (46%), Gaps = 26/191 (13%) Query: 5470 QISDILYKLEYNK--AKPRGYTTIHDTPM---LLHVRKVKDEVSDLKYKEVYQRNKSNCT 5524 ++ YK Y K G+ T+ D P +H K++ SD +YK+ Y+++K Sbjct: 19 EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKGIHN 75 Query: 5525 IEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKL 5584 D + I AK + +++DY+ W PD+ D +QA K+ QSD YK Sbjct: 76 TPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKS 131 Query: 5585 DREFLKGC------KLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQIL 5638 D E+LKG + V KN +N L E + K + +K ++ DTP+++ Sbjct: 132 DLEWLKGIGWLPEGSVEVMRVKNA----QNLLNERLYRIKPEALK----FTSIVDTPEVI 183 Query: 5639 LAKTVSNLVSE 5649 AK + +SE Sbjct: 184 QAKINAVQISE 194 Score = 58.9 bits (141), Expect = 2e-07 Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 13/167 (7%) Query: 5595 SVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKD 5654 ++ DD +V A+ I+SD +YK+ + K +G + D I+ AK LVS+ Y++ Sbjct: 41 TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN 100 Query: 5655 HVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHA 5714 ++ + +T LP+ D + K+ SD YK KG I P Sbjct: 101 YLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-----IGWLPEGSVEV 149 Query: 5715 MEVAKKQSDVAYR--KDAKENLHYTTVADRPDIKKATQAAKQASEVE 5759 M V Q+ + R + E L +T++ D P++ +A A Q SEVE Sbjct: 150 MRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196 Score = 57.8 bits (138), Expect = 4e-07 Identities = 45/189 (23%), Positives = 82/189 (43%), Gaps = 11/189 (5%) Query: 347 KYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPK 406 KYKE Y K G ++P+ A SD+ YK+ YEK+K TP Sbjct: 24 KYKEGYRKQLGH-HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTP- 77 Query: 407 FKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDR 466 + +++Q D ++ L + + K SD YK++ E + Sbjct: 78 LDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137 Query: 467 GKGFFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDL-- 524 G G+ P+ + + + Y++ P+ KFT + D+P ++QA++N+ Q+S++ Sbjct: 138 GIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEK 197 Query: 525 ---NYKAKH 530 N+ +H Sbjct: 198 SRDNFNVRH 206 Score = 57.8 bits (138), Expect = 4e-07 Identities = 51/177 (28%), Positives = 84/177 (47%), Gaps = 15/177 (8%) Query: 6048 KYKQSAEMEKAN---FTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEI 6104 KYK+ + + F ++ D P+ + A + S ++YK+ EKS + T LD I Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 6105 QRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAI 6164 + ++ Q +L D +N + T + D ++++ K+ S LYK D+ I Sbjct: 84 VQAKKCQ----VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139 Query: 6165 GKTP----EMMRVKQTQDHISSVKYK---EAIGQGTPIPDLPEVKRVKETQKHISSV 6214 G P E+MRVK Q+ ++ Y+ EA+ + T I D PEV + K IS V Sbjct: 140 GWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL-KFTSIVDTPEVIQAKINAVQISEV 195 Score = 52.8 bits (125), Expect = 1e-05 Identities = 51/183 (27%), Positives = 78/183 (42%), Gaps = 9/183 (4%) Query: 5295 DISKIKYKENYMSQLGI---WRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAY 5351 ++ KYKE Y QLG +R++ D P+ SD +YK+ KGI Sbjct: 19 EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78 Query: 5352 DTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYE 5411 D A+K + L S Y+ + + + D K A L ++ Y++D E Sbjct: 79 DMMSIVQAKKCQVLVSDIDYRNYLHQ----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134 Query: 5412 QRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQI 5471 K L + K A + +++ YR E KFTSIVDTPE ++ QI Sbjct: 135 WLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQI 192 Query: 5472 SDI 5474 S++ Sbjct: 193 SEV 195 Score = 52.0 bits (123), Expect = 2e-05 Identities = 42/165 (25%), Positives = 79/165 (47%), Gaps = 7/165 (4%) Query: 5091 YKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQ 5150 Y++ L GF L D P V + H K+ S+ Y K + + LD + + Sbjct: 29 YRKQLGHHMGFRT-LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAK 87 Query: 5151 ELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAG 5210 + + +S++ YR +T +PD D+++AK+ LQS LY + Sbjct: 88 KCQVLVSDIDYR----NYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143 Query: 5211 NQTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAK 5255 + + K+ +++++E+ Y+I+ E + K+T + DTP +I+AK Sbjct: 144 EGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAK 186 Score = 51.2 bits (121), Expect = 3e-05 Identities = 55/208 (26%), Positives = 95/208 (45%), Gaps = 15/208 (7%) Query: 5547 YKKQYEANKAH---WKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTV 5603 YK+ Y H ++ D P + A ++ QSD EYK E KG + D + V Sbjct: 25 YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIV 84 Query: 5604 LALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQG 5663 A + ++ SD+ Y+ + + TC +PD ++ AK +L S+N YK ++ G Sbjct: 85 QAKKCQVLVSDIDYR--NYLHQWTC--LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140 Query: 5664 SYTTLPE-TRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQS 5722 LPE + + + VK +++ Y+ K K ++ +++ PEV A A + S Sbjct: 141 ---WLPEGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQIS 193 Query: 5723 DVAYRKDAKENLHYTTVADRPDIKKATQ 5750 +V +D HY + D+ + A Q Sbjct: 194 EVEKSRDNFNVRHYGSYLDQKQLGPAQQ 221 Score = 50.4 bits (119), Expect = 6e-05 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 10/187 (5%) Query: 100 KYKEKFEKTKGQPYASTT---DTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKD 156 KYKE + K G T D + I + Q S+ +Y+ + +K I + Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ-SDREYKKAYEKSKGIHNTPLDMMS 82 Query: 157 IEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKS 216 I AKK VS + Y+ ++ PD +++QA K + S LY D E K Sbjct: 83 IVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138 Query: 217 LFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQK 276 + + S E+ RV AQ L++ Y+ + + +FT + D P++ AK Q+S+ + Sbjct: 139 IGWLPEGSVEVMRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVE 196 Query: 277 YKEDYEN 283 D N Sbjct: 197 KSRDNFN 203 Score = 50.1 bits (118), Expect = 8e-05 Identities = 56/205 (27%), Positives = 82/205 (40%), Gaps = 43/205 (20%) Query: 4860 DTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYV 4919 D P+ + A HA ++ D +YK K++ + D VQA K +SD Y +Y+ Sbjct: 44 DDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYL 102 Query: 4920 HSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYM 4979 H + P D+ +A AY LQS NLYK+ L L Sbjct: 103 H--QWTCLPDQN--DVIQAKKAYDLQSDNLYKSDLEWL---------------------- 136 Query: 4980 SSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTP 5039 K G+ L V + V+ N+ +ERLYR LK + DTP Sbjct: 137 -------------KGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTP 180 Query: 5040 EIRQVKKTQEAVSELIYKSDFFKMQ 5064 E+ Q K +SE+ D F ++ Sbjct: 181 EVIQAKINAVQISEVEKSRDNFNVR 205 Score = 48.1 bits (113), Expect = 3e-04 Identities = 48/175 (27%), Positives = 89/175 (50%), Gaps = 24/175 (13%) Query: 972 AKRASDILNEKKYRQHPDTLKFTSIEDAPIT----VQSKINQAQRSDIAYKAKGEEIIHK 1027 A A+ I ++++Y++ + K I + P+ VQ+K Q SDI Y+ +H+ Sbjct: 51 AIHAAKIQSDREYKKAYEKSK--GIHNTPLDMMSIVQAKKCQVLVSDIDYR----NYLHQ 104 Query: 1028 YNLPPDLPQFIQAKVNAYNI-SENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDV 1086 + PD IQAK AY++ S+N+YK+DL+ L G+ L ++ + K A+ ++ Sbjct: 105 WTCLPDQNDVIQAK-KAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNER 162 Query: 1087 QYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPH 1141 Y + K + + F S+ D P+++ AKI + + + EK++ +N H Sbjct: 163 LY-----RIKPEALKFTSIVDTPEVIQ----AKINAVQ--ISEVEKSRDNFNVRH 206 Score = 47.8 bits (112), Expect = 4e-04 Identities = 45/184 (24%), Positives = 83/184 (45%), Gaps = 10/184 (5%) Query: 5405 KYRADYEQRKDK---YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEH 5461 KY+ Y ++ + + D+P+ + A A S +Y+K YEKSK + +D Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 5462 LRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKS 5521 ++ K +SDI Y+ ++ +T + D ++ +K D SD YK + K Sbjct: 84 VQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138 Query: 5522 NCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFE 5581 + +V + K+A + Y+ + EA K + D P+ +QA +++Q S+ E Sbjct: 139 IGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEVE 196 Query: 5582 YKLD 5585 D Sbjct: 197 KSRD 200 Score = 47.0 bits (110), Expect = 6e-04 Identities = 38/159 (23%), Positives = 72/159 (45%), Gaps = 7/159 (4%) Query: 4615 DTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYH 4674 D P+ + A + +QS +Y A +++ +N D V A + + S++ Y+ H Sbjct: 44 DDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH 103 Query: 4675 QIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHL 4734 Q +T + + D + + +L S NLYK + +K + LP ++ + KN ++L Sbjct: 104 Q----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNL 158 Query: 4735 ASHIKYREEYE--KFKALYTLPRSVDDDPNTARCLRVGK 4771 + YR + E KF ++ P + N + V K Sbjct: 159 LNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEK 197 Score = 47.0 bits (110), Expect = 6e-04 Identities = 50/191 (26%), Positives = 77/191 (40%), Gaps = 48/191 (25%) Query: 2161 RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM 2220 +IQSD EYK+ Y E KG+ +P + + +AKK SD YR Sbjct: 56 KIQSDREYKKAY-EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN-------------- 100 Query: 2221 DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL 2280 Y W +PD D++QAK+ L S LYK E Sbjct: 101 ----------------YLHQWT-------CLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137 Query: 2281 KKGYDLPVDAISVQLAKASRDIASD--YKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVA 2338 G+ LP ++ V K ++++ ++ Y+ K K F S+ D P+++ + A Sbjct: 138 GIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK-------FTSIVDTPEVIQAKINA 189 Query: 2339 KMQSEREYKKD 2349 SE E +D Sbjct: 190 VQISEVEKSRD 200 Score = 46.6 bits (109), Expect = 8e-04 Identities = 53/202 (26%), Positives = 83/202 (41%), Gaps = 9/202 (4%) Query: 5716 EVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSML 5775 EV + YRK ++ + T+ D P A AAK S+ EY+ + K + L Sbjct: 19 EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78 Query: 5776 GRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKAD 5835 I AKK L S + YR N+ + P N K A +L S+ YK+D Sbjct: 79 DMMSIVQAKKCQVLVSDIDYR-NYLHQWTCLPDQNDVIQ-----AKKAYDLQSDNLYKSD 132 Query: 5836 LKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLK-EAT 5894 L+ L + S+ + V N L + Y+ K E K + +I D E + K A Sbjct: 133 LEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAV 190 Query: 5895 ELQSIVKYKEKYEKERGKPMLD 5916 ++ + K ++ + LD Sbjct: 191 QISEVEKSRDNFNVRHYGSYLD 212 Score = 45.8 bits (107), Expect = 0.001 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%) Query: 4180 YRKDWNATKSKYTLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAH 4239 YRK TL + P A AA+I YK+ +E+ K + P D + V A Sbjct: 29 YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGI-HNTPLDMMSIVQAK 87 Query: 4240 HCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKI 4299 C + S++ Y+ ++ Q + +P D ++ + A +Q++ LYK D K Sbjct: 88 KCQVLVSDIDYR-NYLHQ---WTCLPDQND---VIQAKKAYDLQSDNLYKSDLEWLKGIG 140 Query: 4300 NIPADMVSVLAAKQGQTLVSDIDYR 4324 +P V V+ K Q L+++ YR Sbjct: 141 WLPEGSVEVMRVKNAQNLLNERLYR 165 Score = 44.3 bits (103), Expect = 0.004 Identities = 42/158 (26%), Positives = 70/158 (44%), Gaps = 10/158 (6%) Query: 1481 FTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHY 1540 F ++ D V A H K SD YK EK K + ++ +QAK + +SD Y Sbjct: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98 Query: 1541 KADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLV 1600 + + PD ++ AK + ++ SD YK E KG +G+L + +++ Sbjct: 99 -----RNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150 Query: 1601 HYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAK 1638 N + ++R Y+ EA K+ + +D V AK Sbjct: 151 RVKNAQNLLNERLYRIKPEA--LKFTSIVDTPEVIQAK 186 Score = 43.5 bits (101), Expect = 0.007 Identities = 35/106 (33%), Positives = 53/106 (50%), Gaps = 7/106 (6%) Query: 1969 YSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP-DIPQIILAKANAINMSDKL 2027 + TL D V A + AKI ++ YK+A+E K +H P D+ I+ AK + +SD Sbjct: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMSIVQAKKCQVLVSDID 97 Query: 2028 YKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKG 2073 Y+ L + + PD + AK + D+ SD YK + E KG Sbjct: 98 YRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138 Score = 42.0 bits (97), Expect = 0.020 Identities = 46/217 (21%), Positives = 94/217 (43%), Gaps = 53/217 (24%) Query: 1649 YRQSYHHY----TLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKA 1704 YR+ H+ TL D +V + +A +IQSD YK + KGI P++ + + +A Sbjct: 29 YRKQLGHHMGFRTLQDDPKSV-WAIHAAKIQSDREYKKAYEK-SKGIHNTPLDMMSIVQA 86 Query: 1705 KKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMP 1764 KK ++S+ YR Y +W +P Sbjct: 87 KKCQVLVSDIDYRN------------------------------YLHQWT-------CLP 109 Query: 1765 DTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAY 1824 D D++ ++ SD LYK+ E K G+ L ++ + + ++++ ++ Y+ Sbjct: 110 DQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR--- 165 Query: 1825 EQAKGKHIGFRSLEDDPKL----VHFMQVAKMQSDRE 1857 K + + F S+ D P++ ++ +Q+++++ R+ Sbjct: 166 --IKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200 Score = 42.0 bits (97), Expect = 0.020 Identities = 46/206 (22%), Positives = 84/206 (40%), Gaps = 48/206 (23%) Query: 1900 YNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKK 1959 + L D A + +IQSD +YK Y + KGI PL + + KK ++S+ Sbjct: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAY-EKSKGIHNTPLDMMSIVQAKKCQVLVSDID 97 Query: 1960 YRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKAN 2019 YR Y W +PD +I AK Sbjct: 98 YRN------------------------------YLHQWTC-------LPDQNDVIQAKKA 120 Query: 2020 AINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFR 2079 SD LYK LE K G+ L ++ + K ++++ ++ Y+ K + + F Sbjct: 121 YDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRI-----KPEALKFT 174 Query: 2080 SLEDDPKL----VHSMQVAKMQSDRE 2101 S+ D P++ ++++Q+++++ R+ Sbjct: 175 SIVDTPEVIQAKINAVQISEVEKSRD 200 Score = 41.6 bits (96), Expect = 0.027 Identities = 42/154 (27%), Positives = 65/154 (42%), Gaps = 10/154 (6%) Query: 6133 VQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTP----EMMRVKQTQDHISSVKYKEA 6188 +QD P+ + K S YK+ I TP +++ K+ Q +S + Y+ Sbjct: 42 LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY 101 Query: 6189 IGQGTPIPDLPEVKRVKETQKHISSVMYKENL----GTGIPTTVTPEIERVKRNQENFSS 6244 + Q T +PD +V + K+ S +YK +L G G + E+ RVK Q + Sbjct: 102 LHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNE 161 Query: 6245 VLY--KENLGKGIPTPITPEMERVKRNQENFSSV 6276 LY K K TPE+ + K N S V Sbjct: 162 RLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195 Score = 40.0 bits (92), Expect = 0.078 Identities = 39/151 (25%), Positives = 63/151 (41%), Gaps = 6/151 (3%) Query: 5647 VSENKYKDHVKKHLAQG-SYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIM 5705 V KYK+ +K L + TL + +V K SD YKK + K KG N Sbjct: 20 VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHN--TP 77 Query: 5706 LEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHR 5765 L+ + A + SD+ YR + +T + D+ D+ +A +A S+ Y++ Sbjct: 78 LDMMSIVQAKKCQVLVSDIDYRNYLHQ---WTCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134 Query: 5766 KEGSHGLSMLGRPDIEMAKKAAKLSSQVKYR 5796 G G ++ K A L ++ YR Sbjct: 135 WLKGIGWLPEGSVEVMRVKNAQNLLNERLYR 165 Score = 40.0 bits (92), Expect = 0.078 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 7/123 (5%) Query: 5369 YKYKEVFERTKSD---FKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPR 5425 YKYKE + + F+ + D P + +A ++ ++++Y+ YE+ K ++ +D Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 5426 HLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKP 5485 + AK +S I YR NY ++T + D + ++ K SD LYK + K Sbjct: 83 IVQAKKCQVLVSDIDYR-NY---LHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138 Query: 5486 RGY 5488 G+ Sbjct: 139 IGW 141 Score = 40.0 bits (92), Expect = 0.078 Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 16/151 (10%) Query: 4388 KYK---KNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHI 4444 KYK + L ++ FR++ D P+ V A + QSD +YK+ + K+KG + D I Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 4445 SHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKG 4504 +K L S I Y+ + +T ++ AK A + S+ YK E KG Sbjct: 84 VQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138 Query: 4505 HYLAGKVIGEFP-GVVHCLDFQKMRSALNYR 4534 IG P G V + + ++ LN R Sbjct: 139 -------IGWLPEGSVEVMRVKNAQNLLNER 162 Score = 39.3 bits (90), Expect = 0.13 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 7/117 (5%) Query: 2438 ASEIISEKKYRQPPDRNK--FTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMP 2495 A++I S+++Y++ +++K + D M IV AK SD YR Q +P Sbjct: 54 AAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLP 109 Query: 2496 DTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYK 2552 D D++ AK SD LY+ E LK G+ LP ++ + K ++ + +E Y+ Sbjct: 110 DQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165 Score = 38.9 bits (89), Expect = 0.17 Identities = 54/207 (26%), Positives = 85/207 (41%), Gaps = 17/207 (8%) Query: 993 FTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMY 1052 F +++D P +V + +SD YK E+ +N P D+ +QAK +S+ Y Sbjct: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98 Query: 1053 KADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLV 1112 + L + D + AK A SD YK D E KG +G+ + +++ Sbjct: 99 RNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150 Query: 1113 HYMNVAKIQSDREY--KKDYEKTKSKYNTPHDM---FNVVAAKKAQDVVSNVNYKH--SL 1165 N + ++R Y K + K S +TP + N V + + N N +H S Sbjct: 151 RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210 Query: 1166 HHYTYLPDAMDLELSK--NMMQIQSDN 1190 L A ELS+ M SDN Sbjct: 211 LDQKQLGPAQQWELSELSAMWTYPSDN 237 Score = 37.7 bits (86), Expect = 0.39 Identities = 38/142 (26%), Positives = 59/142 (41%), Gaps = 8/142 (5%) Query: 1237 FTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCY 1296 F ++ D P V A K SD YK E K + D+ +QAK +SD+ Y Sbjct: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98 Query: 1297 KRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLV 1356 + H L D + AK + ++ SD YK E KG +G+ + +++ Sbjct: 99 RNYLHQW-----TCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150 Query: 1357 HYMNVAKLQSDREYKKNYENTK 1378 N L ++R Y+ E K Sbjct: 151 RVKNAQNLLNERLYRIKPEALK 172 Score = 37.4 bits (85), Expect = 0.50 Identities = 56/207 (27%), Positives = 85/207 (41%), Gaps = 21/207 (10%) Query: 716 CYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTK-----FTAVTDSPVLLQAQLNTKQLSD 770 C FP+ T + L + + YK K F + D P + A K SD Sbjct: 5 CLFPKPHTYDLS----LPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60 Query: 771 LNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLL 830 YK +E K + P D +Q + +SD Y ++ ++ D ++ Sbjct: 61 REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY-----RNYLHQWTCLPDQNDVI 115 Query: 831 AAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKN-QSDREYRKDYEKS 889 AK SD +YK D E KG IG L M +K A+N ++R YR E Sbjct: 116 QAKKAYDLQSDNLYKSDLEWLKG--IGWLPEGSVEVM--RVKNAQNLLNERLYRIKPEAL 171 Query: 890 KTIYTAPLDMLQVTQAKKSQAIASDVD 916 K +T+ +D +V QAK + S+V+ Sbjct: 172 K--FTSIVDTPEVIQAKINAVQISEVE 196 Score = 37.4 bits (85), Expect = 0.50 Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 51/208 (24%) Query: 421 KYKDSYLKDILGHYVGSF---EDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQ 477 KYK+ Y K LGH++G +DP + SD+ YK YE+ +G P Sbjct: 24 KYKEGYRKQ-LGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTP----- 77 Query: 478 EYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKC 537 D ++QA+ +SD++Y+ + ++ C Sbjct: 78 ----------------------------LDMMSIVQAKKCQVLVSDIDYR--NYLHQWTC 107 Query: 538 HIPPDTPAFIQHKVNAYNL-SDNLYKQDWEKSKAKKFDIKVDAIPLLAAKA-NTKNTSDV 595 PD IQ K AY+L SDNLYK D E K + +P + + KN ++ Sbjct: 108 L--PDQNDVIQAK-KAYDLQSDNLYKSDLEWLKG------IGWLPEGSVEVMRVKNAQNL 158 Query: 596 MYKKDYEKNKGKMIGVLSINDDPKMLHS 623 + ++ Y + K + + SI D P+++ + Sbjct: 159 LNERLY-RIKPEALKFTSIVDTPEVIQA 185 Score = 37.4 bits (85), Expect = 0.50 Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 10/168 (5%) Query: 4645 YNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLY 4704 + + D P V A+ + S+ +YK+ Y + K + T L+ + + + + L S Y Sbjct: 39 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98 Query: 4705 KEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTA 4764 + + LP + AK L S Y+ + E K + LP + Sbjct: 99 RNYLHQWTC----LPDQN-DVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP---EGSVEVM 150 Query: 4765 RCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEID 4812 R L +RLYR + +K + D E++ AK + ++SE++ Sbjct: 151 RVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVE 196 >gi|5453710 LIM and SH3 protein 1 [Homo sapiens] Length = 261 Score = 123 bits (309), Expect = 5e-27 Identities = 94/258 (36%), Positives = 117/258 (45%), Gaps = 66/258 (25%) Query: 6417 VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTD-PITERVKKNMQDFSDINYRG 6475 V DTPE R+++ S V+Y E+FEK+KG VV D P +R+KK S+I Y Sbjct: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 Query: 6476 IQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSR 6535 E E+ R P +P + Q S + RR Sbjct: 125 ------EFEKSR---------------MGPSGGEGMEPERRDSQDGSSY-------RRPL 156 Query: 6536 EQSRSASALSISGGEEKSEHSEAPDHHLST----YSDGGVFAVSTAYKHAKTTELPQQRS 6591 EQ + HH+ T Y V+ +Y K P Sbjct: 157 EQQQP--------------------HHIPTSAPVYQQPQQQPVAQSYGGYKEPAAP---- 192 Query: 6592 SSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGT 6651 VS S P GK +RA+YDY AAD DEVSF+DGD I+NVQ ID+GWMYGT Sbjct: 193 ---------VSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGT 243 Query: 6652 VQRTGRTGMLPANYVEAI 6669 V+RTG TGMLPANYVEAI Sbjct: 244 VERTGDTGMLPANYVEAI 261 Score = 67.0 bits (162), Expect = 6e-10 Identities = 31/90 (34%), Positives = 55/90 (61%), Gaps = 8/90 (8%) Query: 5439 IKYRKNYEKS--------KDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTT 5490 +K K YEK K FT + DTPE+LR + ++ S + YK E+ K K +G++ Sbjct: 41 MKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSV 100 Query: 5491 IHDTPMLLHVRKVKDEVSDLKYKEVYQRNK 5520 + DTP L ++K +D++S++KY E +++++ Sbjct: 101 VADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 62.0 bits (149), Expect = 2e-08 Identities = 39/112 (34%), Positives = 56/112 (50%), Gaps = 4/112 (3%) Query: 5339 DLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYAT 5398 D W K C+ +T TL KN Y K Y K F VAD+P N K + Sbjct: 22 DKFWHKA--CFHCETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQS 78 Query: 5399 QLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSK 5449 +L ++ +Y+ ++E+ K K + +V D P K DQIS IKY + +EKS+ Sbjct: 79 ELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 58.9 bits (141), Expect = 2e-07 Identities = 27/55 (49%), Positives = 38/55 (69%) Query: 83 TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKY 137 TP ++ +L S +YKE+FEK KG+ ++ DTPEL+RIKK QDQ+S +KY Sbjct: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 Score = 58.5 bits (140), Expect = 2e-07 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 6/84 (7%) Query: 6109 ENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPG-----TA 6163 +N K + Y C+ K T+V DTPE LR+K+ + S V YKE+ + Sbjct: 42 KNYKGYEKKPY-CNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSV 100 Query: 6164 IGKTPEMMRVKQTQDHISSVKYKE 6187 + TPE+ R+K+TQD IS++KY E Sbjct: 101 VADTPELQRIKKTQDQISNIKYHE 124 Score = 58.5 bits (140), Expect = 2e-07 Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Query: 6052 SAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSY-YETVLDTPEIQRVREN 6110 +A K +FT V DTPE + +Q L SQ +YKE+ EK+ + V DTPE+QR+++ Sbjct: 54 NAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKT 113 Query: 6111 QKNFSLLQYQCDLKNSK 6127 Q S ++Y + + S+ Sbjct: 114 QDQISNIKYHEEFEKSR 130 Score = 58.2 bits (139), Expect = 3e-07 Identities = 28/63 (44%), Positives = 39/63 (61%) Query: 6384 TPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFE 6443 TPE R K+ E S V Y + F K + V DTPE++R+++TQ IS +KYHE+FE Sbjct: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 Query: 6444 KHK 6446 K + Sbjct: 128 KSR 130 Score = 57.0 bits (136), Expect = 6e-07 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 10/101 (9%) Query: 5393 HFKYATQLMNEKKYRADYEQR--------KDKYHLVVDEPRHLLAKTAGDQISQIKYRKN 5444 H + +N K Y+ YE++ K + +V D P +L K + SQ++Y++ Sbjct: 31 HCETCKMTLNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEE 89 Query: 5445 YEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAK 5484 +EK+K K F+ + DTPE R K QIS+I Y E+ K++ Sbjct: 90 FEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 53.9 bits (128), Expect = 5e-06 Identities = 32/111 (28%), Positives = 61/111 (54%), Gaps = 6/111 (5%) Query: 288 KWSETPCFEVANARMNADNISTRKYQED---FENMKDQIYFMQTETPEYKMNKKAGVAAS 344 K+ CF +M + + + Y++ + Q + M +TPE K+ S Sbjct: 23 KFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQS 82 Query: 345 KVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTK 395 +V+YKE++EKNKGK ++V+ ++ P+L+++K D +S+ Y E +EK++ Sbjct: 83 QVRYKEEFEKNKGKG-FSVV--ADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 53.5 bits (127), Expect = 7e-06 Identities = 36/97 (37%), Positives = 49/97 (50%), Gaps = 10/97 (10%) Query: 5218 HAKDVKDMVSEKKYKIQYEKM--------KDKYTPVPDTPILIRAKRAYWNASDLRYKET 5269 H + K ++ K YK YEK K +T V DTP +R K+ S +RYKE Sbjct: 31 HCETCKMTLNMKNYK-GYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEE 89 Query: 5270 FQKTKGK-YHTVKDALDIVYHRKVTDDISKIKYKENY 5305 F+K KGK + V D ++ +K D IS IKY E + Sbjct: 90 FEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126 Score = 51.6 bits (122), Expect = 3e-05 Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 19/152 (12%) Query: 6056 EKANFTSVVDTPEIIHAQQVKNLSSQKKYKE-------DAEKSMSYYETVLDTPEIQRVR 6108 EK N H + K + K YK +A + V DTPE R++ Sbjct: 16 EKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLK 75 Query: 6109 ENQKNFSLLQYQCDLKNSKGK-ITVVQDTPEILRVKENQKNFSSVLYKED-----VSPGT 6162 + + S ++Y+ + + +KGK +VV DTPE+ R+K+ Q S++ Y E+ + P Sbjct: 76 QQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSG 135 Query: 6163 AIGKTPEMMRVKQTQDHISSVKYKEAIGQGTP 6194 G PE + +QD S Y+ + Q P Sbjct: 136 GEGMEPER---RDSQDGSS---YRRPLEQQQP 161 Score = 51.6 bits (122), Expect = 3e-05 Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 9/156 (5%) Query: 196 VKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQ-FT 254 +KN + KK Y K F D+PE R+ Q + S V YK+ + + + F+ Sbjct: 41 MKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFS 99 Query: 255 PLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQE 314 +AD P+++ KK +Q+S KY E++E G P D+ Y+ Sbjct: 100 VVADTPELQRIKKTQDQISNIKYHEEFEKSRMG-----PSGGEGMEPERRDSQDGSSYRR 154 Query: 315 DFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKE 350 E + Q + + T P Y+ ++ VA S YKE Sbjct: 155 PLE--QQQPHHIPTSAPVYQQPQQQPVAQSYGGYKE 188 Score = 50.8 bits (120), Expect = 4e-05 Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 9/99 (9%) Query: 5858 TSQLASSYQYKKKYEKS--------KGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKE 5909 T ++ + + K YEK K + + D E L LK+ +ELQS V+YKE++EK Sbjct: 34 TCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN 93 Query: 5910 RGKPM-LDFETPTYITAKESQQMQSGKEYRKDYEESIKG 5947 +GK + +TP K++Q S +Y +++E+S G Sbjct: 94 KGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMG 132 Score = 50.4 bits (119), Expect = 6e-05 Identities = 37/101 (36%), Positives = 54/101 (53%), Gaps = 8/101 (7%) Query: 6286 TPLAVTPEMERVKHNQENISSVLYKE----NVGKATATPV-TPEMQRVKRNQENISSVLY 6340 T +A TPE R+K E S V YKE N GK + TPE+QR+K+ Q+ IS++ Y Sbjct: 63 TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 Query: 6341 KENLGKATPTPFTPE-MERVKRNQENFSSVLYKENMRKATP 6380 E K+ P E ME +R+ ++ SS Y+ + + P Sbjct: 123 HEEFEKSRMGPSGGEGMEPERRDSQDGSS--YRRPLEQQQP 161 Score = 47.4 bits (111), Expect = 5e-04 Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 5/62 (8%) Query: 6162 TAIGKTPEMMRVKQTQDHISSVKYKEAI----GQG-TPIPDLPEVKRVKETQKHISSVMY 6216 T + TPE +R+KQ + S V+YKE G+G + + D PE++R+K+TQ IS++ Y Sbjct: 63 TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 Query: 6217 KE 6218 E Sbjct: 123 HE 124 Score = 47.4 bits (111), Expect = 5e-04 Identities = 23/66 (34%), Positives = 40/66 (60%), Gaps = 1/66 (1%) Query: 6027 MANETPDFMRARNATDIASQIKYKQSAEMEKA-NFTSVVDTPEIIHAQQVKNLSSQKKYK 6085 M +TP+ +R + +++ SQ++YK+ E K F+ V DTPE+ ++ ++ S KY Sbjct: 64 MVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYH 123 Query: 6086 EDAEKS 6091 E+ EKS Sbjct: 124 EEFEKS 129 Score = 45.8 bits (107), Expect = 0.001 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 6/89 (6%) Query: 6193 TPIPDLPEVKRVKETQKHISSVMYKE----NLGTGIPTTV-TPEIERVKRNQENFSSVLY 6247 T + D PE R+K+ + S V YKE N G G TPE++R+K+ Q+ S++ Y Sbjct: 63 TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122 Query: 6248 KENLGKGIPTPITPE-MERVKRNQENFSS 6275 E K P E ME +R+ ++ SS Sbjct: 123 HEEFEKSRMGPSGGEGMEPERRDSQDGSS 151 Score = 45.4 bits (106), Expect = 0.002 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 1/111 (0%) Query: 3676 DTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWD 3735 +T ++ L N K Y A K S ++ DTP+ L K S SQ Y + ++ Sbjct: 33 ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91 Query: 3736 ESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDD 3786 ++K K + + AD ++ K ++D S+ KY E +EK + G + +E + Sbjct: 92 KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142 Score = 45.1 bits (105), Expect = 0.002 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 6/84 (7%) Query: 5726 YRKDAKENLHY-----TTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLG-RPD 5779 Y K N HY T VAD P+ + Q ++ S+V Y+ + K G S++ P+ Sbjct: 47 YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPE 106 Query: 5780 IEMAKKAAKLSSQVKYRENFDKEK 5803 ++ KK S +KY E F+K + Sbjct: 107 LQRIKKTQDQISNIKYHEEFEKSR 130 Score = 44.7 bits (104), Expect = 0.003 Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 2/73 (2%) Query: 5985 KGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIA 6044 + T + DTP+ LR K +++ ++ YK + E KG+G + +A +TP+ R + D Sbjct: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVA-DTPELQRIKKTQDQI 117 Query: 6045 SQIKYKQSAEMEK 6057 S IKY + E + Sbjct: 118 SNIKYHEEFEKSR 130 Score = 44.3 bits (103), Expect = 0.004 Identities = 23/98 (23%), Positives = 54/98 (55%), Gaps = 6/98 (6%) Query: 5641 KTVSNLVSENKYKDHVKK-----HLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVK 5695 +T ++ YK + KK H + S+T + +T + + +K+ ++ S YK++F K Sbjct: 33 ETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEK 92 Query: 5696 EKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKEN 5733 KGK +S++ + PE++ + + S++ Y ++ +++ Sbjct: 93 NKGK-GFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129 Score = 44.3 bits (103), Expect = 0.004 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 3/95 (3%) Query: 4376 RVTKNQEMMSQIKYKKNALENYP--NFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKG 4433 ++T N + + K +YP +F V D PE + K S QS V+YKE F K KG Sbjct: 36 KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95 Query: 4434 K-YTFSPDTPHISHSKDMGKLYSTILYKGAWEGTK 4467 K ++ DTP + K S I Y +E ++ Sbjct: 96 KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 43.9 bits (102), Expect = 0.005 Identities = 24/75 (32%), Positives = 37/75 (49%) Query: 4672 NYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQ 4731 N H K +T V +T + R + L S YKE +++ K + + + T L K Sbjct: 54 NAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKT 113 Query: 4732 KHLASHIKYREEYEK 4746 + S+IKY EE+EK Sbjct: 114 QDQISNIKYHEEFEK 128 Score = 43.9 bits (102), Expect = 0.005 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 5/77 (6%) Query: 6353 TPEMERVKRNQENFSSVLYKENMRKA-----TPTPVTPEMERAKRNQENISSVLYSDSFR 6407 TPE R+K+ E S V YKE K + TPE++R K+ Q+ IS++ Y + F Sbjct: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 Query: 6408 KQIQGKAAYVLDTPEMR 6424 K G + PE R Sbjct: 128 KSRMGPSGGEGMEPERR 144 Score = 43.1 bits (100), Expect = 0.009 Identities = 27/117 (23%), Positives = 55/117 (47%), Gaps = 1/117 (0%) Query: 1724 KFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKL 1783 K + +T + LN N +K+ Y + K + ++ DTP+ L + S Sbjct: 27 KACFHCETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVR 85 Query: 1784 YKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDD 1840 YK +E+ K KG+ + D ++ + ++D S+ KY + +E+++ G +E + Sbjct: 86 YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142 Score = 43.1 bits (100), Expect = 0.009 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 9/102 (8%) Query: 5843 VTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGH-YHTIPDNLEQLHLKEATELQSIVK 5901 V D E+L + S+L S +YK+++EK+KG + + D E +K+ + S +K Sbjct: 65 VADTPENLRLKQ---QSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 5902 YKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEE 5943 Y E++EK R P + E + Q G YR+ E+ Sbjct: 122 YHEEFEKSRMGP-----SGGEGMEPERRDSQDGSSYRRPLEQ 158 Score = 42.7 bits (99), Expect = 0.012 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 36/107 (33%) Query: 5169 KSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAKDVKDMVSE 5228 K FT V DTP+ LR K+ +LQSQ Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQV---------------------------------- 84 Query: 5229 KKYKIQYEKMKDK-YTPVPDTPILIRAKRAYWNASDLRYKETFQKTK 5274 +YK ++EK K K ++ V DTP L R K+ S+++Y E F+K++ Sbjct: 85 -RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 42.7 bits (99), Expect = 0.012 Identities = 23/70 (32%), Positives = 37/70 (52%) Query: 2245 KTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIAS 2304 K ++ DTP+ L+ KQ L SQ YK +E+ KG+ + D +Q K ++D S Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 2305 DYKYKQGYRK 2314 + KY + + K Sbjct: 119 NIKYHEEFEK 128 Score = 42.7 bits (99), Expect = 0.012 Identities = 28/110 (25%), Positives = 55/110 (50%), Gaps = 6/110 (5%) Query: 3914 YTSIVDTPEVVLAKSNAENISIPKYREVWDKDK-TSIHIMPDTPEINLARANALNVSNKL 3972 +T + DTPE + K +E S +Y+E ++K+K ++ DTPE+ + +SN Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 3973 YREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGT 4022 Y E +++ + G ++ + + S Y+ L E+Q+ H++ T Sbjct: 122 YHEEFEKSRMGPS---GGEGMEPERRDSQDGSSYRRPL--EQQQPHHIPT 166 Score = 42.4 bits (98), Expect = 0.016 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 4/98 (4%) Query: 4969 HFKHIKDTRYMSSYFKY-KEAY--EHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELY 5025 H + K T M +Y Y K+ Y H +T+ + +++ + + S+ Y+E + Sbjct: 31 HCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEF 90 Query: 5026 HKLKDK-IHTTPDTPEIRQVKKTQEAVSELIYKSDFFK 5062 K K K DTPE++++KKTQ+ +S + Y +F K Sbjct: 91 EKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128 Score = 42.4 bits (98), Expect = 0.016 Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 5/61 (8%) Query: 6229 TPEIERVKRNQENFSSVLYKE----NLGKGIPTPI-TPEMERVKRNQENFSSVLYKENMG 6283 TPE R+K+ E S V YKE N GKG TPE++R+K+ Q+ S++ Y E Sbjct: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 Query: 6284 K 6284 K Sbjct: 128 K 128 Score = 41.2 bits (95), Expect = 0.035 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Query: 525 NYKAKHESEKFKCHIPP-------DTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKV 577 NYK + H P DTP ++ K + S YK+++EK+K K F + Sbjct: 43 NYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA 102 Query: 578 DAIPLLAAKANTKNTSDVMYKKDYEKNK 605 D L K S++ Y +++EK++ Sbjct: 103 DTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 41.2 bits (95), Expect = 0.035 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 7/88 (7%) Query: 772 NYKAKHEGEKFKCHIP-------ADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKV 824 NYK + H P AD P+ ++ + + S YK+++EK+K K F + Sbjct: 43 NYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA 102 Query: 825 DAIPLLAAKANTKNTSDVMYKKDYEKSK 852 D L K S++ Y +++EKS+ Sbjct: 103 DTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 41.2 bits (95), Expect = 0.035 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Query: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSK-YNTPHDMFNVV 1147 KK Y A F + D P+ + +++QS YK+++EK K K ++ D + Sbjct: 49 KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108 Query: 1148 AAKKAQDVVSNVNY 1161 KK QD +SN+ Y Sbjct: 109 RIKKTQDQISNIKY 122 Score = 40.8 bits (94), Expect = 0.046 Identities = 23/72 (31%), Positives = 38/72 (52%) Query: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328 K +TM D P+ L+ K + S V YK ++ KG +V+ D + K +++ S Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 1329 DYKYKEAYEKSK 1340 + KY E +EKS+ Sbjct: 119 NIKYHEEFEKSR 130 Score = 40.8 bits (94), Expect = 0.046 Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 2/73 (2%) Query: 818 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQ 877 + F + D L K ++ S V YK+++EK+KGK G + D P++ KT Sbjct: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117 Query: 878 SDREYRKDYEKSK 890 S+ +Y +++EKS+ Sbjct: 118 SNIKYHEEFEKSR 130 Score = 40.8 bits (94), Expect = 0.046 Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 7/109 (6%) Query: 3671 FTCITDTPEIVLAKNNALTMSKHLYTEAWDADK-TSIHVMPDTPDILLAKSNSANISQKL 3729 FT + DTPE + K + S+ Y E ++ +K V+ DTP++ K IS Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 3730 YTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHI 3778 Y + +++S+M + RD Y+ E+Q+ HHI Sbjct: 122 YHEEFEKSRM------GPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHI 164 Score = 40.4 bits (93), Expect = 0.059 Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 1/111 (0%) Query: 2947 DSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANE 3006 ++ + L N K+ Y A K ++ DTPE + +Q S+ YK E Sbjct: 33 ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91 Query: 3007 EAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDD 3057 + K KG+ + +D + K ++D IS+ KY + + K G +E + Sbjct: 92 KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142 Score = 40.4 bits (93), Expect = 0.059 Identities = 23/70 (32%), Positives = 35/70 (50%) Query: 2731 KTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIAS 2790 K + ++ DTPE L KQ S+ YK E+ K KG+ + D ++ K ++D S Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 2791 EFKYKEGYRK 2800 KY E + K Sbjct: 119 NIKYHEEFEK 128 Score = 40.0 bits (92), Expect = 0.078 Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 3/95 (3%) Query: 5924 TAKESQQMQSGKEYRKD--YEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEES 5981 T K + M++ K Y K ++ T + TP L +K +++ S+ Y+++ E++ Sbjct: 34 TCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN 93 Query: 5982 IRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLE 6016 +GKG + + DTP++ R K ++ +Y + E Sbjct: 94 -KGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 Score = 40.0 bits (92), Expect = 0.078 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Query: 4858 VWDTPEILHAKHAYDLRDDIKYKAHMLKTR-NDYKLVTDTPVYVQAVKSGKQLSDAVYHY 4916 V DTPE L K +L+ ++YK K + + +V DTP + K+ Q+S+ YH Sbjct: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 Query: 4917 DYVHSVRG 4924 ++ S G Sbjct: 125 EFEKSRMG 132 Score = 39.7 bits (91), Expect = 0.10 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 2/73 (2%) Query: 571 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQ 630 + F + D L K ++ S V YK+++EKNKGK V++ D P++ K Sbjct: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA--DTPELQRIKKTQDQI 117 Query: 631 SDRLYKENYEKTK 643 S+ Y E +EK++ Sbjct: 118 SNIKYHEEFEKSR 130 Score = 39.3 bits (90), Expect = 0.13 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 17/114 (14%) Query: 3428 FTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAK-----LNRIN 3481 FT + DTPE + K + ++ Y E ++ +K K V+ DTPE+ K ++ I Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 3482 YSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHI 3535 Y ++ K + S EG + RD Y+ +Q HHI Sbjct: 122 YHEEFEKSRMGPSGGEGME-----------PERRDSQDGSSYRRPLEQQQPHHI 164 Score = 39.3 bits (90), Expect = 0.13 Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 1/64 (1%) Query: 4370 DSVDHVRVTKNQEMMSQIKYKKNALENY-PNFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428 D+ +++R+ + E+ SQ++YK+ +N F V D PE+ K S++KY E F Sbjct: 67 DTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126 Query: 4429 NKAK 4432 K++ Sbjct: 127 EKSR 130 Score = 38.5 bits (88), Expect = 0.23 Identities = 18/72 (25%), Positives = 38/72 (52%) Query: 1513 KHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIAS 1572 K +T+ + P+ ++ K + S YK +++K KG+ + D + K +++ S Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 1573 DCKYKEAYEKAK 1584 + KY E +EK++ Sbjct: 119 NIKYHEEFEKSR 130 Score = 38.5 bits (88), Expect = 0.23 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 1/66 (1%) Query: 5315 IPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG-CYAYDTPDFTLAEKNKTLYSKYKYKE 5373 + D PE+ + ++ S V+YKE+ KG G DTP+ +K + S KY E Sbjct: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 Query: 5374 VFERTK 5379 FE+++ Sbjct: 125 EFEKSR 130 Score = 38.5 bits (88), Expect = 0.23 Identities = 19/67 (28%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Query: 5631 VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYK 5690 V DTP+ L K S L S+ +YK+ +K+ +G ++ + +T + +K+ +S+ Y Sbjct: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKG-FSVVADTPELQRIKKTQDQISNIKYH 123 Query: 5691 KKFVKEK 5697 ++F K + Sbjct: 124 EEFEKSR 130 Score = 38.1 bits (87), Expect = 0.30 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 1/97 (1%) Query: 3190 DSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAME 3249 ++ + L N K+ Y A K ++ DTPE + +Q S+ Y++ E Sbjct: 33 ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91 Query: 3250 EAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRK 3286 + K +G+ + +D + K ++D S+ KY E + K Sbjct: 92 KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128 Score = 38.1 bits (87), Expect = 0.30 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 5026 HKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMIS-LPYTPQVIHCRYVGD 5084 H K DTPE ++K+ E S++ YK +F K +G S + TP++ + D Sbjct: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115 Query: 5085 ITSDIKYKEDLQ 5096 S+IKY E+ + Sbjct: 116 QISNIKYHEEFE 127 Score = 37.7 bits (86), Expect = 0.39 Identities = 30/128 (23%), Positives = 53/128 (41%), Gaps = 6/128 (4%) Query: 4237 HAHHCNDVQSELKYKAEHVKQ--KGHYV--GVPTMRDDPKLVWFEHAGQIQNERLYKEDY 4292 H C + YK K HY + D P+ + + ++Q++ YKE++ Sbjct: 31 HCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEF 90 Query: 4293 HKTKAK-INIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSD 4351 K K K ++ AD + K+ Q +S+I Y + P + ++ + D Q Sbjct: 91 EKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR-DSQDG 149 Query: 4352 NVYRADLE 4359 + YR LE Sbjct: 150 SSYRRPLE 157 Score = 37.7 bits (86), Expect = 0.39 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 6/94 (6%) Query: 724 QEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFK 783 + Y+ +K C H +P K FT V D+P L+ + ++ S + YK + E K K Sbjct: 42 KNYKGYEKKPYCNAH----YP-KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK 96 Query: 784 -CHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSK 816 + AD P+ + + +S+ Y +++EKS+ Sbjct: 97 GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 37.4 bits (85), Expect = 0.50 Identities = 28/110 (25%), Positives = 53/110 (48%), Gaps = 4/110 (3%) Query: 4602 DLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSG 4661 D W K C+ +T ++ K+Y + Y A Q++ +V DTP + Q Sbjct: 22 DKFWHKA--CFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFTMVADTPENLRLKQQS 78 Query: 4662 INASEVKYKENYHQIKDK-YTTVLETVDYDRTRNLKNLYSSNLYKEAWDR 4710 S+V+YKE + + K K ++ V +T + R + ++ S+ Y E +++ Sbjct: 79 ELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128 Score = 37.4 bits (85), Expect = 0.50 Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 1/111 (0%) Query: 1974 DSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLE 2033 ++ M L N K + Y A K ++ D P+ + K + S YK E Sbjct: 33 ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91 Query: 2034 ESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDD 2084 ++K KG+ + D ++ K ++D S+ KY +EK + G +E + Sbjct: 92 KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142 Score = 37.4 bits (85), Expect = 0.50 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%) Query: 1061 KKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKI 1120 K+ + + D K + S V+YK+++EK KGK GF + D P+L Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQ 116 Query: 1121 QSDREYKKDYEKTK 1134 S+ +Y +++EK++ Sbjct: 117 ISNIKYHEEFEKSR 130 Score = 37.0 bits (84), Expect = 0.66 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 1/85 (1%) Query: 1821 KKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSK-TSFHTPVDMLSVV 1879 KK Y A F + D P+ + Q +++QS YK+ +EK+K F D + Sbjct: 49 KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108 Query: 1880 AAKKSQEVATNANYRNVIHTYNMLP 1904 KK+Q+ +N Y M P Sbjct: 109 RIKKTQDQISNIKYHEEFEKSRMGP 133 Score = 37.0 bits (84), Expect = 0.66 Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 1/61 (1%) Query: 5778 PDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLK 5837 P+ K+ ++L SQV+Y+E F+K KGK +L ++ K + + S +KY + + Sbjct: 69 PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQI-SNIKYHEEFE 127 Query: 5838 K 5838 K Sbjct: 128 K 128 Score = 36.6 bits (83), Expect = 0.86 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 7/117 (5%) Query: 3765 KYKEAYEKQK--GHHIGAQS---IEDDPKIMCAIHAGKIQSEREYKKEFQKWKTK-FSSP 3818 K + YEK+ H QS + D P+ + ++QS+ YK+EF+K K K FS Sbjct: 42 KNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVV 101 Query: 3819 VDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLE 3875 D + KK Q +++I Y + P + ++ ++ D Q + Y+ LE Sbjct: 102 ADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157 Score = 36.2 bits (82), Expect = 1.1 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Query: 5918 ETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKD 5977 +TP + K+ ++QS Y++++E++ KG+ + + TP L +K S +Y ++ Sbjct: 67 DTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 Query: 5978 LEESIRG 5984 E+S G Sbjct: 126 FEKSRMG 132 Score = 35.8 bits (81), Expect = 1.5 Identities = 41/171 (23%), Positives = 65/171 (38%), Gaps = 13/171 (7%) Query: 397 KSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDK 456 K+ +CET K L+ K Y +++ V + P + + + S Sbjct: 27 KACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVA--DTPENLRLKQQSELQSQV 84 Query: 457 NYKAEYEEDRGKGFFPQTITQEYEAIKKL-DQCKDHTYKVHPDKTKFTQVTD---SPVLL 512 YK E+E+++GKGF T E + IKK DQ + Y +K++ P Sbjct: 85 RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR 144 Query: 513 QAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSDNLYKQ 563 +Q S L + H HIP P + Q + S YK+ Sbjct: 145 DSQDGSSYRRPLEQQQPH-------HIPTSAPVYQQPQQQPVAQSYGGYKE 188 Score = 35.8 bits (81), Expect = 1.5 Identities = 35/152 (23%), Positives = 60/152 (39%), Gaps = 24/152 (15%) Query: 3164 CKRAAEILSDNIYRQPP------DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDK 3217 CK + + Y + P K FT V D+ E + K + ++ Y E ++K+K Sbjct: 35 CKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNK 94 Query: 3218 TQ-VHIMPDTPEIMLARQ-----NKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKAS 3271 + ++ DTPE+ ++ + I Y E + M + EG + Sbjct: 95 GKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGME-----------PER 143 Query: 3272 RDIASDYKYKEAYRKQLGHHIGARA-VHDDPK 3302 RD Y+ +Q HHI A V+ P+ Sbjct: 144 RDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQ 175 Score = 35.8 bits (81), Expect = 1.5 Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 1/64 (1%) Query: 180 KDKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSL-FYPYNDSPELRRVAQAQKALS 238 K + + D PE ++ + + + S+ Y E++E +K F D+PEL+R+ + Q +S Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 239 DVAY 242 ++ Y Sbjct: 119 NIKY 122 Score = 35.4 bits (80), Expect = 1.9 Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 8/121 (6%) Query: 5513 KEVYQRNKSNCTIE---PDAVHIKAAKDAYKVNTNLDYKKQYEAN----KAHWKWTPDRP 5565 K VY K NC + H + K + Y+K+ N K + D P Sbjct: 10 KIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTP 69 Query: 5566 DFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIE-SDLKYKEKHVKE 5624 + L+ + S QS YK + E KG SV D + ++ T + S++KY E+ K Sbjct: 70 ENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129 Query: 5625 R 5625 R Sbjct: 130 R 130 Score = 35.0 bits (79), Expect = 2.5 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 17/97 (17%) Query: 2029 KLSLEESKKKGYDLRP---------------DAIPIKAAKASRDIASDYKYKYNYEKGKG 2073 K++L KGY+ +P D K ++ S +YK +EK KG Sbjct: 36 KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95 Query: 2074 KMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTK 2110 K GF + D P+L + S+ +Y + +E ++ Sbjct: 96 K--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 34.7 bits (78), Expect = 3.3 Identities = 25/97 (25%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Query: 2322 FRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQELVSDVD 2380 F + D P+ + +++QS+ YK++FEK K K FS D + KK Q+ +S++ Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 2381 YKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLE 2417 Y + P + ++ ++ + Q + Y+ LE Sbjct: 122 YHEEFEKSRMGPSGGEGMEPER-RDSQDGSSYRRPLE 157 Score = 34.7 bits (78), Expect = 3.3 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 2/94 (2%) Query: 3540 IKDDPKMMWSIHVAKIQSDREYKKEFEKWKTK-FSSPVDMLGVVLAKKCQILVSDIDYKH 3598 + D P+ + +++QS YK+EFEK K K FS D + KK Q +S+I Y Sbjct: 65 VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124 Query: 3599 PLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLE 3632 + P + ++ + D Q + Y+ LE Sbjct: 125 EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157 Score = 34.7 bits (78), Expect = 3.3 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Query: 367 SENPQLRQLKAAGDALSDKLYKENYEKTKAKSIN-YCETPKFKLDTVLQNFSSDKKYKDS 425 ++ P+ +LK + S YKE +EK K K + +TP+ + Q+ S+ KY + Sbjct: 66 ADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 Query: 426 YLKDILGHYVGSFEDP 441 + K +G G +P Sbjct: 126 FEKSRMGPSGGEGMEP 141 Score = 34.7 bits (78), Expect = 3.3 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Query: 5073 TPQVIHCRYVGDITSDIKYKEDLQVLKGFG-CFLYDTPDMVRSRHLRKLWSNYLYTDKAR 5131 TP+ + + ++ S ++YKE+ + KG G + DTP++ R + + SN Y ++ Sbjct: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 Query: 5132 KMR 5134 K R Sbjct: 128 KSR 130 Score = 34.7 bits (78), Expect = 3.3 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Query: 1321 KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTK 1378 K + S +YKE +EK+KGK GF + D P+L S+ +Y + +E ++ Sbjct: 75 KQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 34.3 bits (77), Expect = 4.3 Identities = 21/84 (25%), Positives = 37/84 (44%) Query: 2488 KTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIAS 2547 K ++ DTP+ + K S Y+ +E+ K KG+ + D ++ K +++ S Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 2548 EYKYKEGFRKQLGHHIGARNIEDD 2571 KY E F K G +E + Sbjct: 119 NIKYHEEFEKSRMGPSGGEGMEPE 142 Score = 33.9 bits (76), Expect = 5.6 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 1577 KEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK-YHTPLDMVSVT 1635 K+ Y A + F + D P+ + +++QS YK+ +E +K K + D + Sbjct: 49 KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108 Query: 1636 AAKKSQEVATNANYRQSYHHYTLLP 1660 KK+Q+ +N Y + + + P Sbjct: 109 RIKKTQDQISNIKYHEEFEKSRMGP 133 Score = 33.9 bits (76), Expect = 5.6 Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 1/71 (1%) Query: 111 QPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAK-TICHVDEKAKDIEHAKKVSQQVSK 169 Q + DTPE R+K+ + S+V+Y+ + + K V +++ KK Q+S Sbjct: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISN 119 Query: 170 VLYKQNWEDTK 180 + Y + +E ++ Sbjct: 120 IKYHEEFEKSR 130 Score = 33.5 bits (75), Expect = 7.3 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 10/88 (11%) Query: 1223 LNEKKYR---------QHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHK-Y 1272 LN K Y+ H FT + D+P ++ KQ ++ S + YK + E K K + Sbjct: 39 LNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGF 98 Query: 1273 TMSPDLPQFLQAKCNAYNISDVCYKRDW 1300 ++ D P+ + K IS++ Y ++ Sbjct: 99 SVVADTPELQRIKKTQDQISNIKYHEEF 126 Score = 33.5 bits (75), Expect = 7.3 Identities = 17/68 (25%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Query: 3598 HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGW-VPIGSVEVEKVKRAGEI 3656 +P +T + D + ++ ++ +LQS YK + E +G G+ V + E++++K+ + Sbjct: 57 YPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ 116 Query: 3657 LSDRKYRQ 3664 +S+ KY + Sbjct: 117 ISNIKYHE 124 Score = 33.1 bits (74), Expect = 9.5 Identities = 49/232 (21%), Positives = 84/232 (36%), Gaps = 32/232 (13%) Query: 1719 HPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDK-TTIHVMPDTPDILLSRVNQI 1777 H K FT DT E K + Y E++ K+K V+ DTP++ + Q Sbjct: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115 Query: 1778 TMSDKLYKAGWEEEK---KKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGF 1834 +S+ Y +E+ + G + P+ RD Y++ EQ + HI Sbjct: 116 QISNIKYHEEFEKSRMGPSGGEGMEPE---------RRDSQDGSSYRRPLEQQQPHHI-- 164 Query: 1835 RSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYR 1894 P Q + Q + GY+ + + V+ ++S YR Sbjct: 165 ------PTSAPVYQQPQQQPVAQSYGGYK----------EPAAPVSIQRSAPGGGGKRYR 208 Query: 1895 NVIHTYNMLPDAMSFELAKNMMQIQS-DNQYKADYADFMKGIGWLPLGSLEA 1945 V D +SF+ ++ +Q D+ + + G LP +EA Sbjct: 209 AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEA 260 Score = 33.1 bits (74), Expect = 9.5 Identities = 15/81 (18%), Positives = 41/81 (50%) Query: 1028 YNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQ 1087 + + D P+ ++ K + S+ YK + + KG+ + D ++ K + S+++ Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 1088 YKKDYEKAKGKMVGFQSLQDD 1108 Y +++EK++ G + ++ + Sbjct: 122 YHEEFEKSRMGPSGGEGMEPE 142 Score = 33.1 bits (74), Expect = 9.5 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%) Query: 1565 KSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASK 1622 K + S +YKE +EK KGK GF + D P+L S+ +Y + +E S+ Sbjct: 75 KQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 >gi|47087157 nebulette non-muscle isoform [Homo sapiens] Length = 270 Score = 102 bits (254), Expect = 1e-20 Identities = 49/73 (67%), Positives = 59/73 (80%), Gaps = 1/73 (1%) Query: 6598 QTTVSSIPSHPSTAG-KIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTG 6656 QT+VSS+ S + + +RAMYDY A D DEVSF+DGD I+NVQ ID+GWMYGTVQRTG Sbjct: 197 QTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTG 256 Query: 6657 RTGMLPANYVEAI 6669 RTGMLPANY+E + Sbjct: 257 RTGMLPANYIEFV 269 Score = 99.0 bits (245), Expect = 1e-19 Identities = 52/104 (50%), Positives = 67/104 (64%), Gaps = 1/104 (0%) Query: 6384 TPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFE 6443 TPE R K+ E S V Y F + + V DTPE++R++ TQ IS VKYHEDFE Sbjct: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127 Query: 6444 KHKG-CFTPVVTDPITERVKKNMQDFSDINYRGIQRKVVEMEQK 6486 K KG FTPVV DP+TERV+KN Q SD Y+G+ +VEM+++ Sbjct: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRR 171 Score = 78.2 bits (191), Expect = 3e-13 Identities = 42/115 (36%), Positives = 65/115 (56%), Gaps = 1/115 (0%) Query: 5403 EKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEH 5461 EKK + K + V D P +L K + SQ+KY++++E+SK + F+ + DTPE Sbjct: 48 EKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPEL 107 Query: 5462 LRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVY 5516 R + +QIS++ Y ++ K K RG+T + D P+ VRK VSD YK V+ Sbjct: 108 QRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162 Score = 73.9 bits (180), Expect = 5e-12 Identities = 42/106 (39%), Positives = 61/106 (57%), Gaps = 2/106 (1%) Query: 6052 SAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSY-YETVLDTPEIQRVREN 6110 +A K +FT+V DTPE + +Q L SQ KYK D E+S + V DTPE+QR++ Sbjct: 54 NAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRT 113 Query: 6111 QKNFSLLQYQCDLKNSKGK-ITVVQDTPEILRVKENQKNFSSVLYK 6155 Q+ S ++Y D + +KG+ T V D P RV++N + S YK Sbjct: 114 QEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 73.6 bits (179), Expect = 6e-12 Identities = 47/141 (33%), Positives = 70/141 (49%), Gaps = 5/141 (3%) Query: 5339 DLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYAT 5398 D W KG C+ + L N Y K Y K F VAD+P N K + Sbjct: 22 DKYWHKG--CFHCEVCKMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQS 78 Query: 5399 QLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIV 5456 +L ++ KY+ D+E+ K + + +V D P K +QIS +KY +++EK+K + FT +V Sbjct: 79 ELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVV 138 Query: 5457 DTPEHLRTTKVNKQISDILYK 5477 D P R K + +SD YK Sbjct: 139 DDPVTERVRKNTQVVSDAAYK 159 Score = 67.0 bits (162), Expect = 6e-10 Identities = 44/118 (37%), Positives = 61/118 (51%), Gaps = 11/118 (9%) Query: 6110 NQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIG---- 6165 N K + Y C+ K T V DTPE LR+K+ + S V YK D G Sbjct: 43 NYKGYEKKPY-CNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIV 101 Query: 6166 -KTPEMMRVKQTQDHISSVKYKEAI----GQG-TPIPDLPEVKRVKETQKHISSVMYK 6217 TPE+ R+K+TQ+ IS+VKY E G+G TP+ D P +RV++ + +S YK Sbjct: 102 TDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 63.2 bits (152), Expect = 9e-09 Identities = 28/86 (32%), Positives = 54/86 (62%), Gaps = 8/86 (9%) Query: 5443 KNYEKS--------KDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDT 5494 K YEK K FT++ DTPE+LR + ++ S + YK ++ ++K RG++ + DT Sbjct: 45 KGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDT 104 Query: 5495 PMLLHVRKVKDEVSDLKYKEVYQRNK 5520 P L +++ ++++S++KY E +++ K Sbjct: 105 PELQRLKRTQEQISNVKYHEDFEKTK 130 Score = 60.5 bits (145), Expect = 6e-08 Identities = 39/125 (31%), Positives = 65/125 (52%), Gaps = 10/125 (8%) Query: 5860 QLASSYQYKKKYEKS--------KGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERG 5911 ++A + K YEK K + T+ D E L LK+ +ELQS VKYK +E+ +G Sbjct: 36 KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95 Query: 5912 KPM-LDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIAS 5970 + + +TP K +Q+ S +Y +D+E++ KGR T + P V+ T++ S Sbjct: 96 RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT-KGRGFTPVVDDPVTERVRKNTQVVS 154 Query: 5971 EKEYR 5975 + Y+ Sbjct: 155 DAAYK 159 Score = 60.1 bits (144), Expect = 7e-08 Identities = 38/120 (31%), Positives = 64/120 (53%), Gaps = 10/120 (8%) Query: 6077 NLSSQKKYKEDAEKSMSY----YETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGK-IT 6131 N+++ K Y++ + Y + TV DTPE R+++ + S ++Y+ D + SKG+ + Sbjct: 40 NMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFS 99 Query: 6132 VVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEM-----MRVKQTQDHISSVKYK 6186 +V DTPE+ R+K Q+ S+V Y ED G TP + RV++ +S YK Sbjct: 100 IVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 59.3 bits (142), Expect = 1e-07 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 5/94 (5%) Query: 83 TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGD 142 TP ++ +L S KYK FE++KG+ ++ TDTPEL+R+K+ Q+Q+S VKY D + Sbjct: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127 Query: 143 VAK---TICHVDEKAKDIEHAKKVSQQVSKVLYK 173 K VD+ E +K +Q VS YK Sbjct: 128 KTKGRGFTPVVDDPV--TERVRKNTQVVSDAAYK 159 Score = 58.9 bits (141), Expect = 2e-07 Identities = 31/95 (32%), Positives = 56/95 (58%), Gaps = 2/95 (2%) Query: 5918 ETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKD 5977 +TP + K+ ++QS +Y++D+EES KGR + + TP L +K + S +Y +D Sbjct: 67 DTPENLRLKQQSELQSQVKYKRDFEES-KGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125 Query: 5978 LEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYK 6012 E++ +G+G T + D P R + TQ++++ YK Sbjct: 126 FEKT-KGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 58.2 bits (139), Expect = 3e-07 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 3/102 (2%) Query: 5985 KGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIA 6044 + T + DTP+ LR K +++ ++ +YKRD E E KGRG ++ +TP+ R + + Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFE-ESKGRGF-SIVTDTPELQRLKRTQEQI 117 Query: 6045 SQIKYKQSAEMEKA-NFTSVVDTPEIIHAQQVKNLSSQKKYK 6085 S +KY + E K FT VVD P ++ + S YK Sbjct: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 57.8 bits (138), Expect = 4e-07 Identities = 42/160 (26%), Positives = 73/160 (45%), Gaps = 7/160 (4%) Query: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328 K +T D P+ L+ K + S V YKRD+ + +G +++ D + K ++ S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 1329 DYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV 1388 + KY E +EK+KG+ GF + DDP ++ SD YK + + PG +V Sbjct: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV 176 Query: 1389 S-ITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNV 1427 + + Q + Y H T + S++H+ N+ Sbjct: 177 APVLPGAYQQSHSQGYGYM----HQTSVSSMRSMQHSPNL 212 Score = 57.4 bits (137), Expect = 5e-07 Identities = 38/141 (26%), Positives = 72/141 (51%), Gaps = 12/141 (8%) Query: 5650 NKYKDHVKK-----HLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSI 5704 N YK + KK H + S+TT+ +T + + +K+ ++ S YK+ F + KG+ +SI Sbjct: 42 NNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR-GFSI 100 Query: 5705 MLEPPEVKHAMEVAKKQSDVAYRKDAK--ENLHYTTVADRPDIKKATQAAKQASEVEYRA 5762 + + PE++ ++ S+V Y +D + + +T V D P ++ + + S+ Y+ Sbjct: 101 VTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKG 160 Query: 5763 KHRKEGSHGLSMLGRPDIEMA 5783 H H + M RP I +A Sbjct: 161 VH----PHIVEMDRRPGIIVA 177 Score = 57.4 bits (137), Expect = 5e-07 Identities = 32/103 (31%), Positives = 58/103 (56%), Gaps = 3/103 (2%) Query: 5948 RNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILN 6007 ++ T + TP L +K +++ S+ +Y++D EES +G+G + + DTP++ R K + ++ Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEES-KGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 6008 EKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYK 6050 +Y D E + KGRG + ++ P R R T + S YK Sbjct: 119 NVKYHEDFE-KTKGRGFTPVVDD-PVTERVRKNTQVVSDAAYK 159 Score = 56.2 bits (134), Expect = 1e-06 Identities = 39/97 (40%), Positives = 52/97 (53%), Gaps = 10/97 (10%) Query: 6286 TPLAVTPEMERVKHNQENISSVLYK----ENVGKATATPV-TPEMQRVKRNQENISSVLY 6340 T +A TPE R+K E S V YK E+ G+ + TPE+QR+KR QE IS+V Y Sbjct: 63 TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122 Query: 6341 KENLGKATPTPFTPEM-----ERVKRNQENFSSVLYK 6372 E+ K FTP + ERV++N + S YK Sbjct: 123 HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 54.7 bits (130), Expect = 3e-06 Identities = 35/136 (25%), Positives = 65/136 (47%), Gaps = 3/136 (2%) Query: 1724 KFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKL 1783 K + + + ALN +N +K+ Y + K + + DTP+ L + S Sbjct: 27 KGCFHCEVCKMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVK 85 Query: 1784 YKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKL 1843 YK +EE K +G+ + D ++ + +++ S+ KY + +E+ KG+ GF + DDP Sbjct: 86 YKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVT 143 Query: 1844 VHFMQVAKMQSDREYK 1859 + ++ SD YK Sbjct: 144 ERVRKNTQVVSDAAYK 159 Score = 54.7 bits (130), Expect = 3e-06 Identities = 40/97 (41%), Positives = 54/97 (55%), Gaps = 12/97 (12%) Query: 6226 TTV--TPEIERVKRNQENFSSVLYK----ENLGKGIPTPI-TPEMERVKRNQENFSSVLY 6278 TTV TPE R+K+ E S V YK E+ G+G TPE++R+KR QE S+V Y Sbjct: 63 TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122 Query: 6279 KENM----GKG-TPLAVTPEMERVKHNQENISSVLYK 6310 E+ G+G TP+ P ERV+ N + +S YK Sbjct: 123 HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 54.3 bits (129), Expect = 4e-06 Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 9/119 (7%) Query: 525 NYKAKHESEKFKCHIPP-------DTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKV 577 NYK + H P DTP ++ K + S YK+D+E+SK + F I Sbjct: 43 NYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVT 102 Query: 578 DAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYK 636 D L K + S+V Y +D+EK KG+ G + DDP K + SD YK Sbjct: 103 DTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 53.9 bits (128), Expect = 5e-06 Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 12/98 (12%) Query: 6193 TPIPDLPEVKRVKETQKHISSVMYK----ENLGTGIP-TTVTPEIERVKRNQENFSSVLY 6247 T + D PE R+K+ + S V YK E+ G G T TPE++R+KR QE S+V Y Sbjct: 63 TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122 Query: 6248 KENL----GKGIPTPIT--PEMERVKRNQENFSSVLYK 6279 E+ G+G TP+ P ERV++N + S YK Sbjct: 123 HEDFEKTKGRGF-TPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 53.5 bits (127), Expect = 7e-06 Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 9/119 (7%) Query: 772 NYKAKHEGEKFKCHIP-------ADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKV 824 NYK + H P AD P+ ++ + + S YK+D+E+SK + F I Sbjct: 43 NYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVT 102 Query: 825 DAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYR 883 D L K + S+V Y +D+EK+KG+ G + DDP K + SD Y+ Sbjct: 103 DTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 53.1 bits (126), Expect = 9e-06 Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 2/95 (2%) Query: 1033 DLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDY 1092 D P+ ++ K + S+ YK D ++ +G+ + TD ++ K ++ S+V+Y +D+ Sbjct: 67 DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126 Query: 1093 EKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYK 1127 EK KG+ GF + DDP ++ SD YK Sbjct: 127 EKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 52.8 bits (125), Expect = 1e-05 Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Query: 5169 KSIFTSVPDTPDLLRAKRGQKLQSQYLYV-ELATKERPHHHAGNQTTALKHAKDVKDMVS 5227 K FT+V DTP+ LR K+ +LQSQ Y + + T L+ K ++ +S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 5228 EKKYKIQYEKMKDK-YTPVPDTPILIRAKRAYWNASDLRYK 5267 KY +EK K + +TPV D P+ R ++ SD YK Sbjct: 119 NVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 52.4 bits (124), Expect = 2e-05 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 2/111 (1%) Query: 4672 NYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQ 4731 N H K +TTV +T + R + L S YK ++ K + + + T L K Sbjct: 54 NAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRT 113 Query: 4732 KHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVY 4782 + S++KY E++EK K P V DDP T R + ++ D Y+ V+ Sbjct: 114 QEQISNVKYHEDFEKTKGRGFTP--VVDDPVTERVRKNTQVVSDAAYKGVH 162 Score = 52.4 bits (124), Expect = 2e-05 Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 10/96 (10%) Query: 6317 TATPVTPEMQRVKRNQENISSVLYKENLGKATPTPF-----TPEMERVKRNQENFSSVLY 6371 T TPE R+K+ E S V YK + ++ F TPE++R+KR QE S+V Y Sbjct: 63 TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122 Query: 6372 KENMRKA-----TPTPVTPEMERAKRNQENISSVLY 6402 E+ K TP P ER ++N + +S Y Sbjct: 123 HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158 Score = 52.4 bits (124), Expect = 2e-05 Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 5/99 (5%) Query: 290 SETPCFEVANARMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYK 349 ++TP E + ++ S KY+ DFE K + + + T+TPE + K+ S VKY Sbjct: 66 ADTP--ENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123 Query: 350 EDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYK 388 ED+EK KG+ P ++P +++ +SD YK Sbjct: 124 EDFEKTKGR---GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 52.0 bits (123), Expect = 2e-05 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 2/103 (1%) Query: 2245 KTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIAS 2304 K + DTP+ L+ KQ L SQ YK +EE+ +G+ + D +Q K +++ S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 2305 DYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYK 2347 + KY + + K G GF + DDP ++ S+ YK Sbjct: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 52.0 bits (123), Expect = 2e-05 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 2/96 (2%) Query: 5314 SIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG-CYAYDTPDFTLAEKNKTLYSKYKYK 5372 ++ D PE+ + ++ S VKYK D KG G DTP+ ++ + S KY Sbjct: 64 TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123 Query: 5373 EVFERTKS-DFKYVADSPINRHFKYATQLMNEKKYR 5407 E FE+TK F V D P+ + TQ++++ Y+ Sbjct: 124 EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 51.6 bits (122), Expect = 3e-05 Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 3/126 (2%) Query: 1978 MVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKK 2037 M L NN K + Y A K + D P+ + K + S YK EESK Sbjct: 37 MALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95 Query: 2038 KGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQ 2097 +G+ + D ++ K +++ S+ KY ++EK KG+ GF + DDP + ++ Sbjct: 96 RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVV 153 Query: 2098 SDREYK 2103 SD YK Sbjct: 154 SDAAYK 159 Score = 50.8 bits (120), Expect = 4e-05 Identities = 37/158 (23%), Positives = 69/158 (43%), Gaps = 5/158 (3%) Query: 1513 KHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIAS 1572 K +T + P+ ++ K + S YK D++++ +G+ + D + K ++ S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 1573 DCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMV 1632 + KY E +EK KG+ GF + DDP ++ SD YK + P +V Sbjct: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV 176 Query: 1633 SVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRN 1670 + Q+ + + Y H T + +++HS N Sbjct: 177 APVLPGAYQQ---SHSQGYGYMHQTSVSSMRSMQHSPN 211 Score = 50.4 bits (119), Expect = 6e-05 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 6/121 (4%) Query: 479 YEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFK-C 537 Y+ +K C H +P K FT V D+P L+ + S+ S + YK E K + Sbjct: 44 YKGYEKKPYCNAH----YP-KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGF 98 Query: 538 HIPPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMY 597 I DTP + K +S+ Y +D+EK+K + F VD + NT+ SD Y Sbjct: 99 SIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158 Query: 598 K 598 K Sbjct: 159 K 159 Score = 50.4 bits (119), Expect = 6e-05 Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 2/112 (1%) Query: 5228 EKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGK-YHTVKDALDI 5286 EKK K +T V DTP +R K+ S ++YK F+++KG+ + V D ++ Sbjct: 48 EKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPEL 107 Query: 5287 VYHRKVTDDISKIKYKENYMSQLGI-WRSIPDRPEHFHHRAVTDTVSDVKYK 5337 ++ + IS +KY E++ G + + D P R T VSD YK Sbjct: 108 QRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 50.1 bits (118), Expect = 8e-05 Identities = 37/105 (35%), Positives = 52/105 (49%), Gaps = 6/105 (5%) Query: 4374 HVRVTKNQEMMSQIK-YKKNALEN--YP--NFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428 H V K M+ K Y+K N YP +F +V D PE + K S QS VKYK F Sbjct: 31 HCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDF 90 Query: 4429 NKAKGK-YTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYT 4472 ++KG+ ++ DTP + K + S + Y +E TK G+T Sbjct: 91 EESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135 Score = 50.1 bits (118), Expect = 8e-05 Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 3/127 (2%) Query: 3679 EIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESK 3738 ++ L NN K Y A K S + DTP+ L K S SQ Y + ++ESK Sbjct: 36 KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94 Query: 3739 MKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKI 3798 + + + D ++ K +++ S+ KY E +EK KG G + DDP ++ Sbjct: 95 GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152 Query: 3799 QSEREYK 3805 S+ YK Sbjct: 153 VSDAAYK 159 Score = 49.3 bits (116), Expect = 1e-04 Identities = 25/76 (32%), Positives = 48/76 (63%), Gaps = 3/76 (3%) Query: 322 QIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDA 381 Q + +TPE K+ S+VKYK D+E++KG+ ++++ ++ P+L++LK + Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRG-FSIV--TDTPELQRLKRTQEQ 116 Query: 382 LSDKLYKENYEKTKAK 397 +S+ Y E++EKTK + Sbjct: 117 ISNVKYHEDFEKTKGR 132 Score = 49.3 bits (116), Expect = 1e-04 Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 2/94 (2%) Query: 4370 DSVDHVRVTKNQEMMSQIKYKKNALENY-PNFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428 D+ +++R+ + E+ SQ+KYK++ E+ F V D PE+ K S+VKY E F Sbjct: 67 DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126 Query: 4429 NKAKGK-YTFSPDTPHISHSKDMGKLYSTILYKG 4461 K KG+ +T D P + ++ S YKG Sbjct: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKG 160 Score = 48.9 bits (115), Expect = 2e-04 Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 3/104 (2%) Query: 818 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQ 877 + F D L K ++ S V YK+D+E+SKG+ G + D P++ +T + Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117 Query: 878 SDREYRKDYEKSK-TIYTAPLDMLQVTQAKKSQAIASDVDYKHI 920 S+ +Y +D+EK+K +T +D + +K+ + SD YK + Sbjct: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGV 161 Score = 48.5 bits (114), Expect = 2e-04 Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 4/81 (4%) Query: 454 SDKNYKAEYEEDRGKGFFPQTITQEYEAIKKL-DQCKDHTYKVHPDKTK---FTQVTDSP 509 S YK ++EE +G+GF T T E + +K+ +Q + Y +KTK FT V D P Sbjct: 82 SQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDP 141 Query: 510 VLLQAQVNSKQLSDLNYKAKH 530 V + + N++ +SD YK H Sbjct: 142 VTERVRKNTQVVSDAAYKGVH 162 Score = 48.1 bits (113), Expect = 3e-04 Identities = 35/127 (27%), Positives = 56/127 (44%), Gaps = 3/127 (2%) Query: 2950 EQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEAK 3009 + L NN K+ Y A K + DTPE + +Q S+ YK EE+K Sbjct: 36 KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94 Query: 3010 KKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKI 3069 +G+ + +D + K +++ IS+ KY + + K G G + DDP ++ Sbjct: 95 GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152 Query: 3070 QSDREYK 3076 SD YK Sbjct: 153 VSDAAYK 159 Score = 48.1 bits (113), Expect = 3e-04 Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 3/126 (2%) Query: 2708 MVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKR 2767 M L NN + Y A K + + DTPE L KQ S+ YK EE+K Sbjct: 37 MALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95 Query: 2768 KGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQ 2827 +G+ + D ++ K +++ S KY E + K G G + DDP ++ Sbjct: 96 RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVV 153 Query: 2828 SDREYK 2833 SD YK Sbjct: 154 SDAAYK 159 Score = 48.1 bits (113), Expect = 3e-04 Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 9/127 (7%) Query: 5837 KKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGH-YHTIPDNLEQLHLKEATE 5895 K+ V D E+L + S+L S +YK+ +E+SKG + + D E LK E Sbjct: 59 KQSFTTVADTPENLRLKQ---QSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQE 115 Query: 5896 LQSIVKYKEKYEKERGK---PMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTG 5952 S VKY E +EK +G+ P++D P +++ Q+ S Y+ + ++ G Sbjct: 116 QISNVKYHEDFEKTKGRGFTPVVD--DPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPG 173 Query: 5953 LEVTPAL 5959 + V P L Sbjct: 174 IIVAPVL 180 Score = 48.1 bits (113), Expect = 3e-04 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 2/99 (2%) Query: 111 QPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAK-TICHVDEKAKDIEHAKKVSQQVSK 169 Q + + DTPE R+K+ + S+VKY+ D + +K + +++ K+ +Q+S Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISN 119 Query: 170 VLYKQNWEDTKDKYLLP-PDAPELVQAVKNTAMFSKKLY 207 V Y +++E TK + P D P + KNT + S Y Sbjct: 120 VKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158 Score = 47.8 bits (112), Expect = 4e-04 Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 11/153 (7%) Query: 169 KVLYKQNWEDTKDKY----LLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDS 224 KV+Y + DKY + ++ + N + KK Y K F D+ Sbjct: 10 KVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADT 68 Query: 225 PELRRVAQAQKALSDVAYKKGLAEQQAQ-FTPLADPPDIEFAKKVTNQVSKQKYKEDYEN 283 PE R+ Q + S V YK+ E + + F+ + D P+++ K+ Q+S KY ED+E Sbjct: 69 PENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE- 127 Query: 284 KIKGKWSETPCFE---VANARMNADNISTRKYQ 313 K KG+ TP + R N +S Y+ Sbjct: 128 KTKGR-GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 47.8 bits (112), Expect = 4e-04 Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 3/127 (2%) Query: 3436 EQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESK 3495 + L NN K+ Y A K++ + DTPE + K S YK EESK Sbjct: 36 KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94 Query: 3496 KEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKI 3555 G+ + D +Q K +++ S+ KY E + K G G + DDP ++ Sbjct: 95 GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152 Query: 3556 QSDREYK 3562 SD YK Sbjct: 153 VSDAAYK 159 Score = 47.0 bits (110), Expect = 6e-04 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 4/96 (4%) Query: 686 EDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKL-DQCKDHTYKVHP 744 + P + + + S YK ++EE KG+ + T T E + +K+ +Q + Y Sbjct: 67 DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126 Query: 745 DKTK---FTAVTDSPVLLQAQLNTKQLSDLNYKAKH 777 +KTK FT V D PV + + NT+ +SD YK H Sbjct: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162 Score = 47.0 bits (110), Expect = 6e-04 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 3/87 (3%) Query: 1077 KAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSK 1136 K + S V+YK+D+E++KG+ GF + D P+L + S+ +Y +D+EKTK + Sbjct: 75 KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132 Query: 1137 YNTP-HDMFNVVAAKKAQDVVSNVNYK 1162 TP D +K VVS+ YK Sbjct: 133 GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 46.6 bits (109), Expect = 8e-04 Identities = 30/95 (31%), Positives = 52/95 (54%), Gaps = 2/95 (2%) Query: 4613 VWDTPQILHAKKSYDLQSQLQYTAAGKENL-QNYNLVTDTPLYVTAVQSGINASEVKYKE 4671 V DTP+ L K+ +LQSQ++Y +E+ + +++VTDTP ++ S VKY E Sbjct: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE 124 Query: 4672 NYHQIKDK-YTTVLETVDYDRTRNLKNLYSSNLYK 4705 ++ + K + +T V++ +R R + S YK Sbjct: 125 DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 46.2 bits (108), Expect = 0.001 Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 10/159 (6%) Query: 5513 KEVYQRNKSNCTIE---PDAVHIKAAKDAYKVNTNLDYKKQYEAN----KAHWKWTPDRP 5565 K VY K NC + H + K A +N Y+K+ N K + D P Sbjct: 10 KVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTP 69 Query: 5566 DFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIE-SDLKYKEKHVKE 5624 + L+ + S QS +YK D E KG S+ D + L+ T + S++KY E K Sbjct: 70 ENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT 129 Query: 5625 RGTCHA-VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQ 5662 +G V D P + + +VS+ YK V H+ + Sbjct: 130 KGRGFTPVVDDPVTERVRKNTQVVSDAAYKG-VHPHIVE 167 Score = 46.2 bits (108), Expect = 0.001 Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 3/127 (2%) Query: 3193 EQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAK 3252 + L NN K+ Y A K + DTPE + +Q S+ Y++ EE+K Sbjct: 36 KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94 Query: 3253 KEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKV 3312 G+ + +D + K +++ S+ KY E + K G G V DDP +V Sbjct: 95 GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152 Query: 3313 QSDREYK 3319 SD YK Sbjct: 153 VSDAAYK 159 Score = 46.2 bits (108), Expect = 0.001 Identities = 30/107 (28%), Positives = 55/107 (51%), Gaps = 5/107 (4%) Query: 1160 NYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGW-IPIGSLDVEKVKK 1218 N + +T + D + K ++QS YK D+ KG G+ I + +++++K+ Sbjct: 54 NAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEE-SKGRGFSIVTDTPELQRLKR 112 Query: 1219 AGDALNEKKYRQHPDTLK---FTSIVDSPVMVQAKQNTKQVSDILYK 1262 + ++ KY + + K FT +VD PV + ++NT+ VSD YK Sbjct: 113 TQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 46.2 bits (108), Expect = 0.001 Identities = 41/165 (24%), Positives = 75/165 (45%), Gaps = 8/165 (4%) Query: 5631 VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYK 5690 V DTP+ L K S L S+ KYK ++ +G ++ + +T + +K + +S+ Y Sbjct: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRG-FSIVTDTPELQRLKRTQEQISNVKYH 123 Query: 5691 KKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKA-- 5748 + F K KG+ ++ +++ P + + + SD AY+ + H + RP I A Sbjct: 124 EDFEKTKGR-GFTPVVDDPVTERVRKNTQVVSDAAYK---GVHPHIVEMDRRPGIIVAPV 179 Query: 5749 -TQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQ 5792 A +Q+ Y H+ S SM P++ + S+Q Sbjct: 180 LPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQ 224 Score = 45.8 bits (107), Expect = 0.001 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 5/113 (4%) Query: 4966 DTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELY 5025 DTP +K + S KYK +E +K G+++ ++R S Y E + Sbjct: 67 DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126 Query: 5026 HKLKDKIHT-TPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVI 5077 K K + T D P +V+K + VS+ YK + H++ + P +I Sbjct: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKG----VHPHIVEMDRRPGII 175 Score = 44.3 bits (103), Expect = 0.004 Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 2/101 (1%) Query: 3914 YTSIVDTPEVVLAKSNAENISIPKYREVWDKDK-TSIHIMPDTPEINLARANALNVSNKL 3972 +T++ DTPE + K +E S KY+ +++ K I+ DTPE+ + +SN Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 3973 YREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDH 4012 Y E +++ K G +D + + + ++ SD YK H Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162 Score = 43.9 bits (102), Expect = 0.005 Identities = 27/102 (26%), Positives = 52/102 (50%), Gaps = 4/102 (3%) Query: 3598 HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGW-VPIGSVEVEKVKRAGEI 3656 +P +T + D + ++ ++ +LQS YK D E +G G+ + + E++++KR E Sbjct: 57 YPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQ 116 Query: 3657 LSDRKYRQPADQLK---FTCITDTPEIVLAKNNALTMSKHLY 3695 +S+ KY + ++ K FT + D P + N +S Y Sbjct: 117 ISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158 Score = 43.5 bits (101), Expect = 0.007 Identities = 40/171 (23%), Positives = 69/171 (40%), Gaps = 19/171 (11%) Query: 4858 VWDTPEILHAKHAYDLRDDIKYKAHMLKTRN-DYKLVTDTPVYVQAVKSGKQLSDAVYHY 4916 V DTPE L K +L+ +KYK +++ + +VTDTP + ++ +Q+S+ YH Sbjct: 65 VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE 124 Query: 4917 DYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDT 4976 D+ + P +R ++ S YK G PH + Sbjct: 125 DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK-------------GVHPHIVEMDRR 171 Query: 4977 RYMSSYFKYKEAYE--HTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELY 5025 + AY+ H++ YGY +R + + + R YR +Y Sbjct: 172 PGIIVAPVLPGAYQQSHSQGYGYM---HQTSVSSMRSMQHSPNLRTYRAMY 219 Score = 43.1 bits (100), Expect = 0.009 Identities = 29/111 (26%), Positives = 52/111 (46%), Gaps = 6/111 (5%) Query: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSK-YNTPHDMFNVV 1147 KK Y A F ++ D P+ + +++QS +YK+D+E++K + ++ D + Sbjct: 49 KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108 Query: 1148 AAKKAQDVVSNVNYKHSLHH-----YTYLPDAMDLELSKNMMQIQSDNVYK 1193 K+ Q+ +SNV Y +T + D E + Q+ SD YK Sbjct: 109 RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 43.1 bits (100), Expect = 0.009 Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 2/103 (1%) Query: 2488 KTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIAS 2547 K + DTP+ + K S Y+ +EE K +G+ + D ++ K ++E S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 2548 EYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYK 2590 KY E F K G G + DDP ++ SD YK Sbjct: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 43.1 bits (100), Expect = 0.009 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 2/102 (1%) Query: 4155 NFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSK--YTLTETPLLHTAQEAARILDQY 4212 +FT V D + + KQ E+ +KY++D+ +K + +T+TP L + + Sbjct: 61 SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 120 Query: 4213 LYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEH 4254 Y E +E+ K G+ D V S+ YK H Sbjct: 121 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162 Score = 42.7 bits (99), Expect = 0.012 Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 21/138 (15%) Query: 2029 KLSLEESKKKGYDLRP---------------DAIPIKAAKASRDIASDYKYKYNYEKGKG 2073 K++L + KGY+ +P D K ++ S KYK ++E+ KG Sbjct: 36 KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95 Query: 2074 KMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPA--DMLSVTAAKDAQAN 2131 + GF + D P+L + + S+ +Y +++E TK TP D ++ K+ Q Sbjct: 96 R--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV- 152 Query: 2132 ITNTNYKHLIHKYILLPD 2149 +++ YK +H +I+ D Sbjct: 153 VSDAAYKG-VHPHIVEMD 169 Score = 42.7 bits (99), Expect = 0.012 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Query: 253 FTPLADPPDIEFAKKVTNQVSKQKYKEDYE-NKIKGKWSETPCFEVANARMNADNISTRK 311 FT +AD P+ K+ + S+ KYK D+E +K +G T E+ + + IS K Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 312 YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYK 349 Y EDFE K + + + P + +K S YK Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 42.7 bits (99), Expect = 0.012 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 5/99 (5%) Query: 937 KKAYALQSDVEYKADYNSWMKGCGW-VPFGSLEMEKAKRASDILNEKKYRQHPDTLK--- 992 K+ LQS V+YK D+ KG G+ + + E+++ KR + ++ KY + + K Sbjct: 75 KQQSELQSQVKYKRDFEE-SKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRG 133 Query: 993 FTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLP 1031 FT + D P+T + + N SD AYK I+ P Sbjct: 134 FTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRP 172 Score = 42.4 bits (98), Expect = 0.016 Identities = 35/142 (24%), Positives = 54/142 (38%), Gaps = 14/142 (9%) Query: 955 WMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHP------DTLKFTSIEDAPITVQSKIN 1008 W KGC E K A ++ N K Y + P FT++ D P ++ K Sbjct: 25 WHKGC-------FHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQ 77 Query: 1009 QAQRSDIAYKAKGEEIIHK-YNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLR 1067 +S + YK EE + +++ D P+ + K IS Y D + +G+ Sbjct: 78 SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPV 137 Query: 1068 TDAIPIRAAKAARQAASDVQYK 1089 D + Q SD YK Sbjct: 138 VDDPVTERVRKNTQVVSDAAYK 159 Score = 42.0 bits (97), Expect = 0.020 Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 2/92 (2%) Query: 5073 TPQVIHCRYVGDITSDIKYKEDLQVLKGFG-CFLYDTPDMVRSRHLRKLWSNYLYTDKAR 5131 TP+ + + ++ S +KYK D + KG G + DTP++ R + ++ SN Y + Sbjct: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127 Query: 5132 KMRDK-YKVVLDTPEYRKVQELKTHLSELVYR 5162 K + + + V+D P +V++ +S+ Y+ Sbjct: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 41.6 bits (96), Expect = 0.027 Identities = 29/107 (27%), Positives = 55/107 (51%), Gaps = 8/107 (7%) Query: 571 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQ 630 + F D L K ++ S V YK+D+E++KG+ G + D P++ + + Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117 Query: 631 SDRLYKENYEKTKAKS----MNYCETPKYQLDTQLKNFSEARYKDLY 673 S+ Y E++EKTK + ++ T + + +TQ+ S+A YK ++ Sbjct: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV--VSDAAYKGVH 162 Score = 41.2 bits (95), Expect = 0.035 Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 6/111 (5%) Query: 1577 KEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK-YHTPLDMVSVT 1635 K+ Y A + F ++ D P+ + +++QS +YK+ +E SK + + D + Sbjct: 49 KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108 Query: 1636 AAKKSQEVATNANYRQSYHH-----YTLLPDALNVEHSRNAMQIQSDNLYK 1681 K++QE +N Y + + +T + D E R Q+ SD YK Sbjct: 109 RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 40.8 bits (94), Expect = 0.046 Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 1/98 (1%) Query: 3428 FTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAKLNRINYSDKL 3486 FT++ DTPE + K + ++ Y ++ K + ++ DTPE+ K + S+ Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 3487 YKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYK 3524 Y E++K G+ +D + + + + SD YK Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 40.0 bits (92), Expect = 0.078 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 4/100 (4%) Query: 3846 WTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGW-MPQGSPEVLRVKNAQNIFCDSV 3904 +T + D + ++ K+ +LQS YK D E +G G+ + +PE+ R+K Q + Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 3905 YRTPVVNLK---YTSIVDTPEVVLAKSNAENISIPKYREV 3941 Y K +T +VD P + N + +S Y+ V Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGV 161 Score = 40.0 bits (92), Expect = 0.078 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 4/98 (4%) Query: 2388 WTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPL-GSLEAEKNKRASEIISEKK 2446 +T + D + ++ K+ ELQS+ YK D E +G G+S + + E ++ KR E IS K Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 2447 YRQPPDRNK---FTSIPDAMDIVLAKTNAKNRSDRLYR 2481 Y + ++ K FT + D + N + SD Y+ Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 39.7 bits (91), Expect = 0.10 Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 4/102 (3%) Query: 3355 HPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGW-VPIDSLEVVRAKRAGEL 3413 +P + + D + + ++ +LQS YK D E KG G+ + D+ E+ R KR E Sbjct: 57 YPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQ 116 Query: 3414 LSDTIYRQRPETLK---FTSITDTPEQVLAKNNALNMNKRLY 3452 +S+ Y + E K FT + D P + N ++ Y Sbjct: 117 ISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158 Score = 39.3 bits (90), Expect = 0.13 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 6/111 (5%) Query: 1821 KKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSK-TSFHTPVDMLSVV 1879 KK Y A F ++ D P+ + Q +++QS +YK+ +E+SK F D + Sbjct: 49 KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108 Query: 1880 AAKKSQEVATNANYRNVIHT-----YNMLPDAMSFELAKNMMQIQSDNQYK 1925 K++QE +N Y + + D E + Q+ SD YK Sbjct: 109 RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 39.3 bits (90), Expect = 0.13 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Query: 2297 KASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTK 2356 K ++ S KYK+ + + G GF + D P+L + S +Y +DFEK K + Sbjct: 75 KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132 Query: 2357 -FSSPVDMLGVVLAKKCQELVSDVDYK 2382 F+ VD +K ++VSD YK Sbjct: 133 GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 38.1 bits (87), Expect = 0.30 Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 6/111 (5%) Query: 1333 KEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTK-TSYHTPGDMVSIT 1391 K+ Y + F ++ D P+ + ++LQS +YK+++E +K + D + Sbjct: 49 KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108 Query: 1392 AAKMAQDVATNVNYKQPLHH-----YTYLPDAMSLEHTRNVNQIQSDNVYK 1437 K Q+ +NV Y + +T + D E R Q+ SD YK Sbjct: 109 RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 38.1 bits (87), Expect = 0.30 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 1/98 (1%) Query: 3671 FTCITDTPEIVLAKNNALTMSKHLYTEAWDADK-TSIHVMPDTPDILLAKSNSANISQKL 3729 FT + DTPE + K + S+ Y ++ K ++ DTP++ K IS Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 3730 YTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYK 3767 Y + ++++K + + D + + + + SD YK Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 37.7 bits (86), Expect = 0.39 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 2/92 (2%) Query: 5778 PDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLK 5837 P+ K+ ++L SQVKY+ +F++ KG+ +L + +K S VKY D + Sbjct: 69 PENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQR-LKRTQEQISNVKYHEDFE 127 Query: 5838 KLH-KPVTDMKESLIMNHVLNTSQLASSYQYK 5868 K + T + + + V +Q+ S YK Sbjct: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 37.0 bits (84), Expect = 0.66 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 4/98 (4%) Query: 4088 WTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGW-MPNDSVSVNHAKHAADIFSEKK 4146 +T + D + ++ K+ ELQS YK D E +G G+ + D+ + K + S K Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 4147 YRTKIETL---NFTPVDDRVDYVTAKQSGEILDDIKYR 4181 Y E FTPV D +++ +++ D Y+ Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 37.0 bits (84), Expect = 0.66 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query: 2540 KASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTK 2599 K E+ S+ KYK F + G G + D P++ + S+ +Y +DFEK K + Sbjct: 75 KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132 Query: 2600 -FSSPVDMLGVVLAKKCQTLVSDVDYK 2625 F+ VD +K +VSD YK Sbjct: 133 GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 36.6 bits (83), Expect = 0.86 Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 5/107 (4%) Query: 3253 KEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKV 3312 K+ + +D + K ++ S KYK + + G G V D P++ + Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQ 116 Query: 3313 QSDREYKKDFEKYKTRYSSP-VDMLGIVLAKKCQTLVSDVDYK--HP 3356 S+ +Y +DFEK K R +P VD +K +VSD YK HP Sbjct: 117 ISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHP 163 Score = 36.2 bits (82), Expect = 1.1 Identities = 46/185 (24%), Positives = 78/185 (42%), Gaps = 12/185 (6%) Query: 3997 KASREIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAK 4056 K E+ S KYK D E+ KG +T + + R +++ N + Y D+ K K + Sbjct: 75 KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ-RLKRTQEQISNVK-YHEDFEKTKGR 132 Query: 4057 IQSPV--DMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQA---KKAYELQSDNV 4111 +PV D ++ KN+Q +VSD Y+ M + +I A AY+ Sbjct: 133 GFTPVVDDPVTERVRKNTQ-VVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHSQG 191 Query: 4112 Y----KADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVT 4167 Y + + +R + PN ++A E +R +N P+DD Y T Sbjct: 192 YGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGT 251 Query: 4168 AKQSG 4172 +++G Sbjct: 252 VQRTG 256 Score = 35.8 bits (81), Expect = 1.5 Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Query: 4643 QNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDK-YTTVLETVDYDRTRNLKNLYSS 4701 Q++ V DTP + Q S+VKYK ++ + K + ++ V +T + R + + S+ Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISN 119 Query: 4702 NLYKEAWDRVKATSY 4716 Y E +++ K + Sbjct: 120 VKYHEDFEKTKGRGF 134 Score = 35.8 bits (81), Expect = 1.5 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 4/92 (4%) Query: 3887 SPEVLRVKNAQNIFCDSVYRTPVVNLK---YTSIVDTPEVVLAKSNAENISIPKYREVWD 3943 +PE LR+K + Y+ K ++ + DTPE+ K E IS KY E ++ Sbjct: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127 Query: 3944 KDK-TSIHIMPDTPEINLARANALNVSNKLYR 3974 K K + D P R N VS+ Y+ Sbjct: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 35.4 bits (80), Expect = 1.9 Identities = 27/113 (23%), Positives = 54/113 (47%), Gaps = 11/113 (9%) Query: 4499 YEKQ---KGHY--LAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKAN-VHIPNDMMN 4552 YEK+ HY + + + P + +++S + Y++ +E++K I D Sbjct: 47 YEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPE 106 Query: 4553 HVLAKRCQYILSDLEYRHYFHQ-----WTSLLEEPNVIRVRNAQEILSDNVYK 4600 KR Q +S+++Y F + +T ++++P RVR +++SD YK Sbjct: 107 LQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 35.4 bits (80), Expect = 1.9 Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 6/98 (6%) Query: 2322 FRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQELVSDVD 2380 F ++ D P+ + +++QS+ +YK+DFE+ K + FS D + K+ QE +S+V Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 2381 Y-----KNYLHQWTCLPDQNDVVQAKKVYELQSENLYK 2413 Y K +T + D + +K ++ S+ YK Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 35.4 bits (80), Expect = 1.9 Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query: 2783 KASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTK 2842 K ++ S+ KYK + + G G + D P++ + S+ +Y +DFEK K + Sbjct: 75 KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132 Query: 2843 -FSSPVDMLGVVLAKKCQTLVSDVDYK 2868 F+ VD +K +VSD YK Sbjct: 133 GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 35.4 bits (80), Expect = 1.9 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 5/85 (5%) Query: 4242 NDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINI 4301 +++QS++KYK + + KG G + D P+L + + + Y ED+ KTK + Sbjct: 78 SELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135 Query: 4302 PA--DMVSVLAAKQGQTLVSDIDYR 4324 P D V+ K Q +VSD Y+ Sbjct: 136 PVVDDPVTERVRKNTQ-VVSDAAYK 159 Score = 34.3 bits (77), Expect = 4.3 Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 2/98 (2%) Query: 4192 TLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYK 4251 T+ +TP ++ + + Q YK +E K G+ + D + S +KY Sbjct: 64 TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123 Query: 4252 AEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYK 4289 + K KG G + DDP Q+ ++ YK Sbjct: 124 EDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 34.3 bits (77), Expect = 4.3 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 6/96 (6%) Query: 4756 SVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMK-IHIVPDMVEMVTAKDSQKKVSEIDY- 4813 +V D P R + +L Y+ +E++K + IV D E+ K +Q+++S + Y Sbjct: 64 TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123 Query: 4814 ----RLRLHEWICHPDLQVNDHVRKVTDQISDIVYK 4845 + + + D V + VRK T +SD YK Sbjct: 124 EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 33.5 bits (75), Expect = 7.3 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Query: 3946 KTSIHIMPDTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIAS 4004 K S + DTPE + + S Y+ ++E K G + D +Q K ++E S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 4005 DYKYKLDHEKQKG 4017 + KY D EK KG Sbjct: 119 NVKYHEDFEKTKG 131 Score = 33.5 bits (75), Expect = 7.3 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 5/108 (4%) Query: 367 SENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYC-ETPKFKLDTVLQNFSSDKKYKDS 425 ++ P+ +LK + S YK ++E++K + + +TP+ + Q S+ KY + Sbjct: 66 ADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125 Query: 426 YLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEY----EEDRGKG 469 + K + +DP K T SD YK + E DR G Sbjct: 126 FEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPG 173 Score = 33.1 bits (74), Expect = 9.5 Identities = 24/104 (23%), Positives = 46/104 (44%), Gaps = 5/104 (4%) Query: 4484 KHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKAN 4543 K + S++KYK +E+ KG + ++ + P + Q+ S + Y + +E TK Sbjct: 75 KQQSELQSQVKYKRDFEESKGRGFS--IVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132 Query: 4544 VHIP--NDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVI 4585 P +D + + K Q ++SD Y+ + P +I Sbjct: 133 GFTPVVDDPVTERVRKNTQ-VVSDAAYKGVHPHIVEMDRRPGII 175 >gi|20357552 cortactin isoform a [Homo sapiens] Length = 550 Score = 63.5 bits (153), Expect = 7e-09 Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 13/123 (10%) Query: 6546 ISGGEEKSEHS-EAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTTVSSI 6604 +SG E + +S EA D+ ++ G +A Y+ A E P + +T Sbjct: 437 VSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESA---EAPGHYPAEDSTYD------ 487 Query: 6605 PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN 6664 + + G A+YDY AA DE+SF D I N++ ID+GW G + GR G+ PAN Sbjct: 488 -EYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK--GRYGLFPAN 544 Query: 6665 YVE 6667 YVE Sbjct: 545 YVE 547 >gi|20357556 cortactin isoform b [Homo sapiens] Length = 513 Score = 63.5 bits (153), Expect = 7e-09 Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 13/123 (10%) Query: 6546 ISGGEEKSEHS-EAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTTVSSI 6604 +SG E + +S EA D+ ++ G +A Y+ A E P + +T Sbjct: 400 VSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESA---EAPGHYPAEDSTYD------ 450 Query: 6605 PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN 6664 + + G A+YDY AA DE+SF D I N++ ID+GW G + GR G+ PAN Sbjct: 451 -EYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK--GRYGLFPAN 507 Query: 6665 YVE 6667 YVE Sbjct: 508 YVE 510 >gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo sapiens] Length = 492 Score = 60.1 bits (144), Expect = 7e-08 Identities = 53/193 (27%), Positives = 82/193 (42%), Gaps = 24/193 (12%) Query: 6499 RVWRTNPGSVFDYDPAEDNI--QSRSLHMINVQAQRRSREQSRSASALSISGGEEKSEHS 6556 R +R+ P S+F+Y+P + +I R + R SAS S KSE + Sbjct: 122 RKFRSEPRSIFEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPA 181 Query: 6557 EAP-----DHHLSTYSDGGV------------FAVST--AYKHAKTTELPQQRSSSVATQ 6597 P D S S G V F S+ + AK E P+ SS++ Sbjct: 182 VGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDM 241 Query: 6598 -QTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTG 6656 ++ P +A+YD+ A + E+SFK GD + ++ ID+ W G + G Sbjct: 242 GRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHG 299 Query: 6657 RTGMLPANYVEAI 6669 R G+ P +YVE + Sbjct: 300 RVGIFPISYVEKL 312 Score = 50.1 bits (118), Expect = 8e-05 Identities = 21/58 (36%), Positives = 35/58 (60%) Query: 6612 GKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 G+ F+A+Y+Y + DE+ ++ D I ++ D+GW GT +RT G P NYV+ + Sbjct: 435 GEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 492 Score = 46.6 bits (109), Expect = 8e-04 Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Query: 6605 PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN 6664 P+ P G+ A Y++ A E+S + GD +I ++ +D+ W G + T R G+ P + Sbjct: 326 PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVS 384 Query: 6665 YVEAI 6669 YVE + Sbjct: 385 YVEVV 389 >gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo sapiens] Length = 644 Score = 60.1 bits (144), Expect = 7e-08 Identities = 53/193 (27%), Positives = 82/193 (42%), Gaps = 24/193 (12%) Query: 6499 RVWRTNPGSVFDYDPAEDNI--QSRSLHMINVQAQRRSREQSRSASALSISGGEEKSEHS 6556 R +R+ P S+F+Y+P + +I R + R SAS S KSE + Sbjct: 274 RKFRSEPRSIFEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPA 333 Query: 6557 EAP-----DHHLSTYSDGGV------------FAVST--AYKHAKTTELPQQRSSSVATQ 6597 P D S S G V F S+ + AK E P+ SS++ Sbjct: 334 VGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDM 393 Query: 6598 -QTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTG 6656 ++ P +A+YD+ A + E+SFK GD + ++ ID+ W G + G Sbjct: 394 GRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHG 451 Query: 6657 RTGMLPANYVEAI 6669 R G+ P +YVE + Sbjct: 452 RVGIFPISYVEKL 464 Score = 50.1 bits (118), Expect = 8e-05 Identities = 21/58 (36%), Positives = 35/58 (60%) Query: 6612 GKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 G+ F+A+Y+Y + DE+ ++ D I ++ D+GW GT +RT G P NYV+ + Sbjct: 587 GEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 644 Score = 46.6 bits (109), Expect = 8e-04 Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Query: 6605 PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN 6664 P+ P G+ A Y++ A E+S + GD +I ++ +D+ W G + T R G+ P + Sbjct: 478 PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVS 536 Query: 6665 YVEAI 6669 YVE + Sbjct: 537 YVEVV 541 >gi|19224660 protein kinase C and casein kinase substrate in neurons 3 [Homo sapiens] Length = 424 Score = 58.5 bits (140), Expect = 2e-07 Identities = 36/89 (40%), Positives = 48/89 (53%), Gaps = 4/89 (4%) Query: 6584 TELPQQRSSSVATQQTTVSSIPSHPSTA--GKIFRAMYDYMAADADEVSFKDGDAIINVQ 6641 T P Q S T Q S P A G RA+YDY +ADE+SF+ G+ ++ + Sbjct: 335 TAPPPQSPGSPGTGQDEEWSDEESPRKAATGVRVRALYDYAGQEADELSFRAGEELLKMS 394 Query: 6642 AIDE-GWMYGTVQRTGRTGMLPANYVEAI 6669 DE GW G +Q +GR G+ PANYVE + Sbjct: 395 EEDEQGWCQGQLQ-SGRIGLYPANYVECV 422 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 57.8 bits (138), Expect = 4e-07 Identities = 104/515 (20%), Positives = 216/515 (41%), Gaps = 58/515 (11%) Query: 5675 VHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENL 5734 +H+ E TK ++ K +++ + ++ E H + K+ ++A Sbjct: 336 LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHET-LEMKEEEIAQL------- 387 Query: 5735 HYTTVADRPDIKKATQAAKQASEVEYRAKHR--KEGSHGLSMLGRPDIEMAKKAAKLSSQ 5792 R IK+ T ++ E + +++ +E LS + + K A++ Q Sbjct: 388 -------RSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 440 Query: 5793 VKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLKKLHKPVTDMKESLIM 5852 +K E +E+ + + S++ + + D +SE + A L+KLH+ KE + Sbjct: 441 IKTIEKTSEEERIS--LQQELSRVKQEVVDVMKKSSEEQI-AKLQKLHEKELARKEQELT 497 Query: 5853 NHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGK 5912 L T + Q K EKS+ Y I EQ +E+ L+ + K+ E Sbjct: 498 KK-LQTREREFQEQMKVALEKSQSEYLKISQEKEQ---QESLALEELELQKKAILTESEN 553 Query: 5913 PMLDF--ETPTYIT------AKESQQMQSGKEYRKDYEESIKG-RNLTGLEVTPALLHVK 5963 + D E TY T + + +Q K KD ++ +N E+T ++ K Sbjct: 554 KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEIT--VMVEK 611 Query: 5964 YATKIASEKEYRKDLE----ESIRGKGLTEMEDTPDMLRAKNATQILNEKEY-------- 6011 + T++ S K + L + ++ + TEME + + T +L +KE Sbjct: 612 HKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKET-LLKDKEIIFQAHIEE 670 Query: 6012 --KRDLE-LEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPE 6068 ++ LE L+VK L ++++E + ++AR+ + + Q+ +M K + +D + Sbjct: 671 MNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKM-KQELEAKMDEQK 729 Query: 6069 IIHAQQVKNLSSQKKYK----EDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLK 6124 H QQV ++ + + E A K +L + ++E+Q + L + D+K Sbjct: 730 NHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENL--EADIK 787 Query: 6125 NSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVS 6159 S+G++ ++ + ++ + + Y+E ++ Sbjct: 788 RSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 822 Score = 36.2 bits (82), Expect = 1.1 Identities = 65/343 (18%), Positives = 136/343 (39%), Gaps = 46/343 (13%) Query: 90 QKMQDLFSPNKYK------------EKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKY 137 +K++DL K K E+ E+ KG A T K+ + E+K Sbjct: 331 EKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAET---------KRQMHETLEMKE 381 Query: 138 RMDGDVAKTICHVDEKAKDIEHAKKVSQ-----QVSKVLYK-QNWEDTKDKYLLPPDAPE 191 + I + + +++ K+ S+ ++ K L Q E+ + K L + E Sbjct: 382 EEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRK--LKAEMDE 439 Query: 192 LVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQA 251 ++ ++ T+ + ++ K ++A+ QK ++K LA ++ Sbjct: 440 QIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL-----HEKELARKEQ 494 Query: 252 QFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRK 311 + T + EF +++ +V+ +K + +Y KI + + + + I T Sbjct: 495 ELTKKLQTREREFQEQM--KVALEKSQSEYL-KISQEKEQQESLALEELELQKKAILTES 551 Query: 312 YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKE-----DYEKNKGKADYNVLPA 366 + +++ + +T E + + + + +K + K+ + EKNK + V+ Sbjct: 552 -ENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVE 610 Query: 367 SENPQLRQLKAAGDAL-SDKL--YKENYEKTKAKSINYCETPK 406 +L LK DAL ++KL K+ Y+ K CE K Sbjct: 611 KHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEK 653 >gi|171906575 drebrin-like isoform c [Homo sapiens] Length = 439 Score = 56.2 bits (134), Expect = 1e-06 Identities = 30/61 (49%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Query: 6609 STAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEA 6668 S G RA+YDY AAD E+SF + I ++ IDEGW G G GM PANYVE Sbjct: 379 SGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVEL 437 Query: 6669 I 6669 I Sbjct: 438 I 438 >gi|62198235 drebrin-like isoform b [Homo sapiens] Length = 430 Score = 56.2 bits (134), Expect = 1e-06 Identities = 30/61 (49%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Query: 6609 STAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEA 6668 S G RA+YDY AAD E+SF + I ++ IDEGW G G GM PANYVE Sbjct: 370 SGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVEL 428 Query: 6669 I 6669 I Sbjct: 429 I 429 >gi|21361670 drebrin-like isoform a [Homo sapiens] Length = 431 Score = 56.2 bits (134), Expect = 1e-06 Identities = 30/61 (49%), Positives = 35/61 (57%), Gaps = 1/61 (1%) Query: 6609 STAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEA 6668 S G RA+YDY AAD E+SF + I ++ IDEGW G G GM PANYVE Sbjct: 371 SGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVEL 429 Query: 6669 I 6669 I Sbjct: 430 I 430 >gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo sapiens] Length = 671 Score = 55.1 bits (131), Expect = 2e-06 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 13/99 (13%) Query: 6584 TELPQQRSSSVATQQTTVSSI--PSHPSTAGKI-----------FRAMYDYMAADADEVS 6630 T+ P+ ++ ++ T +S PSHP G +RAMY Y + DE+ Sbjct: 573 TQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDELE 632 Query: 6631 FKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 ++GD + +Q D+GW G +RT + G P NYV + Sbjct: 633 LREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 671 Score = 42.4 bits (98), Expect = 0.016 Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 2/57 (3%) Query: 6613 KIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 K R +D+ A E++ + GD + + +D+ W+ G + GR G+ PANYVE + Sbjct: 383 KAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEG--EHHGRLGIFPANYVEVL 437 Score = 42.0 bits (97), Expect = 0.020 Identities = 18/51 (35%), Positives = 30/51 (58%) Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVE 6667 A Y + E+SF+ G+ I ++ ++E W G + TGR G+ PA+YV+ Sbjct: 461 AQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQ 511 >gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo sapiens] Length = 329 Score = 55.1 bits (131), Expect = 2e-06 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 13/99 (13%) Query: 6584 TELPQQRSSSVATQQTTVSSI--PSHPSTAGKI-----------FRAMYDYMAADADEVS 6630 T+ P+ ++ ++ T +S PSHP G +RAMY Y + DE+ Sbjct: 231 TQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDELE 290 Query: 6631 FKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 ++GD + +Q D+GW G +RT + G P NYV + Sbjct: 291 LREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 329 Score = 42.4 bits (98), Expect = 0.016 Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 2/57 (3%) Query: 6613 KIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 K R +D+ A E++ + GD + + +D+ W+ G + GR G+ PANYVE + Sbjct: 41 KAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEG--EHHGRLGIFPANYVEVL 95 Score = 42.0 bits (97), Expect = 0.020 Identities = 18/51 (35%), Positives = 30/51 (58%) Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVE 6667 A Y + E+SF+ G+ I ++ ++E W G + TGR G+ PA+YV+ Sbjct: 119 AQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQ 169 >gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo sapiens] Length = 905 Score = 54.7 bits (130), Expect = 3e-06 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 2/87 (2%) Query: 6585 ELPQQRSSSVATQQTTVSSIPSHPSTAGKIF--RAMYDYMAADADEVSFKDGDAIINVQA 6642 +L + S V Q P T+ +F +A+Y Y+ + DE+ +DGD + ++ Sbjct: 817 DLTESEKSYVQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEK 876 Query: 6643 IDEGWMYGTVQRTGRTGMLPANYVEAI 6669 D+GW GT +RT + G P NYV+ + Sbjct: 877 CDDGWFVGTSRRTKQFGTFPGNYVKPL 903 Score = 40.0 bits (92), Expect = 0.078 Identities = 17/53 (32%), Positives = 29/53 (54%) Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 A +++ E+SF+ G+ I ++ +DE W G + T R G+ P YV+ I Sbjct: 725 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 777 Score = 37.7 bits (86), Expect = 0.39 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 6616 RAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 RA +D+ A E+ + GD + + ID+ W G + GR G+ P Y+E + Sbjct: 650 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 701 >gi|24308229 protein kinase C and casein kinase substrate in neurons 1 [Homo sapiens] Length = 444 Score = 54.3 bits (129), Expect = 4e-06 Identities = 40/140 (28%), Positives = 66/140 (47%), Gaps = 13/140 (9%) Query: 6533 RSREQSRSASALSISGGEEKSEH-SEAPDH-HLSTYSDGGVFAVSTAYKHAKTTELPQQR 6590 + +Q + A ++++ E S+A D +S+Y G +A + + Sbjct: 315 KKEKQPKKAEGVALTNATGAVESTSQAGDRGSVSSYDRGQPYATEWS---------DDES 365 Query: 6591 SSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDE-GWMY 6649 + +T + P + G RA+YDY + DE+SFK GD + + DE GW Sbjct: 366 GNPFGGSETNGGANPFEDDSKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCR 425 Query: 6650 GTVQRTGRTGMLPANYVEAI 6669 G + +G+ G+ PANYVEAI Sbjct: 426 GRLD-SGQLGLYPANYVEAI 444 >gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo sapiens] Length = 740 Score = 53.9 bits (128), Expect = 5e-06 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%) Query: 6590 RSSSVATQQTTVSS---IPSHPSTAGKIF--RAMYDYMAADADEVSFKDGDAIINVQAID 6644 RS++ + QQ P T+ +F +A+Y Y+ + DE+ +DGD + ++ D Sbjct: 654 RSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCD 713 Query: 6645 EGWMYGTVQRTGRTGMLPANYVEAI 6669 +GW GT +RT + G P NYV+ + Sbjct: 714 DGWFVGTSRRTKQFGTFPGNYVKPL 738 Score = 40.0 bits (92), Expect = 0.078 Identities = 17/53 (32%), Positives = 29/53 (54%) Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 A +++ E+SF+ G+ I ++ +DE W G + T R G+ P YV+ I Sbjct: 580 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 632 Score = 37.7 bits (86), Expect = 0.39 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 6616 RAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 RA +D+ A E+ + GD + + ID+ W G + GR G+ P Y+E + Sbjct: 505 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 556 >gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo sapiens] Length = 781 Score = 53.9 bits (128), Expect = 5e-06 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%) Query: 6590 RSSSVATQQTTVSS---IPSHPSTAGKIF--RAMYDYMAADADEVSFKDGDAIINVQAID 6644 RS++ + QQ P T+ +F +A+Y Y+ + DE+ +DGD + ++ D Sbjct: 695 RSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCD 754 Query: 6645 EGWMYGTVQRTGRTGMLPANYVEAI 6669 +GW GT +RT + G P NYV+ + Sbjct: 755 DGWFVGTSRRTKQFGTFPGNYVKPL 779 Score = 40.0 bits (92), Expect = 0.078 Identities = 17/53 (32%), Positives = 29/53 (54%) Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 A +++ E+SF+ G+ I ++ +DE W G + T R G+ P YV+ I Sbjct: 621 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 673 Score = 37.7 bits (86), Expect = 0.39 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 6616 RAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 RA +D+ A E+ + GD + + ID+ W G + GR G+ P Y+E + Sbjct: 546 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 597 >gi|7661700 sorbin and SH3 domain containing 1 isoform 2 [Homo sapiens] Length = 816 Score = 53.9 bits (128), Expect = 5e-06 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%) Query: 6590 RSSSVATQQTTVSS---IPSHPSTAGKIF--RAMYDYMAADADEVSFKDGDAIINVQAID 6644 RS++ + QQ P T+ +F +A+Y Y+ + DE+ +DGD + ++ D Sbjct: 730 RSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCD 789 Query: 6645 EGWMYGTVQRTGRTGMLPANYVEAI 6669 +GW GT +RT + G P NYV+ + Sbjct: 790 DGWFVGTSRRTKQFGTFPGNYVKPL 814 Score = 40.0 bits (92), Expect = 0.078 Identities = 17/53 (32%), Positives = 29/53 (54%) Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 A +++ E+SF+ G+ I ++ +DE W G + T R G+ P YV+ I Sbjct: 656 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 708 Score = 38.9 bits (89), Expect = 0.17 Identities = 40/209 (19%), Positives = 79/209 (37%), Gaps = 25/209 (11%) Query: 6481 VEMEQKRND-QDQETITGLRVWRTNPGSVFDYDPAEDNIQSRS----------------- 6522 ++ +RND + + R +R P S+++Y P + ++ + Sbjct: 429 LKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSSAISPTPEISSETP 488 Query: 6523 --LHMINVQAQRRSREQSRSASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKH 6580 ++ N A +R E + L+ E + S + G+ S++ Sbjct: 489 GYIYSSNFHAVKR--ESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSAS- 545 Query: 6581 AKTTELPQQRSSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINV 6640 K +E P+ + + T H + RA +D+ A E+ + GD + Sbjct: 546 TKDSESPRHFIPADYLESTEEFIRRRHDDKEMRPARAKFDFKAQTLKELPLQKGDIVYIY 605 Query: 6641 QAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 + ID+ W G + GR G+ P Y+E + Sbjct: 606 KQIDQNWYEG--EHHGRVGIFPRTYIELL 632 >gi|78000160 sorbin and SH3 domain containing 1 isoform 1 [Homo sapiens] Length = 684 Score = 53.9 bits (128), Expect = 5e-06 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%) Query: 6590 RSSSVATQQTTVSS---IPSHPSTAGKIF--RAMYDYMAADADEVSFKDGDAIINVQAID 6644 RS++ + QQ P T+ +F +A+Y Y+ + DE+ +DGD + ++ D Sbjct: 598 RSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCD 657 Query: 6645 EGWMYGTVQRTGRTGMLPANYVEAI 6669 +GW GT +RT + G P NYV+ + Sbjct: 658 DGWFVGTSRRTKQFGTFPGNYVKPL 682 Score = 40.0 bits (92), Expect = 0.078 Identities = 17/53 (32%), Positives = 29/53 (54%) Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 A +++ E+SF+ G+ I ++ +DE W G + T R G+ P YV+ I Sbjct: 524 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 576 Score = 38.9 bits (89), Expect = 0.17 Identities = 40/209 (19%), Positives = 79/209 (37%), Gaps = 25/209 (11%) Query: 6481 VEMEQKRND-QDQETITGLRVWRTNPGSVFDYDPAEDNIQSRS----------------- 6522 ++ +RND + + R +R P S+++Y P + ++ + Sbjct: 297 LKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSSAISPTPEISSETP 356 Query: 6523 --LHMINVQAQRRSREQSRSASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKH 6580 ++ N A +R E + L+ E + S + G+ S++ Sbjct: 357 GYIYSSNFHAVKR--ESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSAS- 413 Query: 6581 AKTTELPQQRSSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINV 6640 K +E P+ + + T H + RA +D+ A E+ + GD + Sbjct: 414 TKDSESPRHFIPADYLESTEEFIRRRHDDKEMRPARAKFDFKAQTLKELPLQKGDIVYIY 473 Query: 6641 QAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 + ID+ W G + GR G+ P Y+E + Sbjct: 474 KQIDQNWYEG--EHHGRVGIFPRTYIELL 500 >gi|148747351 protein kinase C and casein kinase substrate in neurons 2 [Homo sapiens] Length = 486 Score = 53.9 bits (128), Expect = 5e-06 Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 17/148 (11%) Query: 6538 SRSASALSISGGEEKSEHSEAP-------DHHLSTYSDGGVFAVSTAYKHAKTTELPQQR 6590 S+ +S L++ +S S++ D ST S+ + KT P Sbjct: 339 SKPSSTLNVPSNPAQSAQSQSSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDW 398 Query: 6591 SSSVATQ--QTTVSSIPSHP----STAGKIFR--AMYDYMAADADEVSFKDGDAIINVQA 6642 S + +T ++ S+P +T+G R A+YDY + DE+SFK GD + ++ Sbjct: 399 SDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMED 458 Query: 6643 IDE-GWMYGTVQRTGRTGMLPANYVEAI 6669 DE GW G + G+ G+ PANYVEAI Sbjct: 459 EDEQGWCKGRLD-NGQVGLYPANYVEAI 485 Score = 35.8 bits (81), Expect = 1.5 Identities = 55/211 (26%), Positives = 89/211 (42%), Gaps = 23/211 (10%) Query: 5783 AKKAAKLSSQVKYR-ENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLKKLHK 5841 A++ ++L +VK N D EK K + Q+ K+ +E ++ K K Sbjct: 90 AERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKE--AEDGFRKAQKPWAK 147 Query: 5842 PVTDMKESLIMNHVL-NTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIV 5900 + +++ + +H +LA S + K + S P+ L++L K Q ++ Sbjct: 148 KLKEVEAAKKAHHAACKEEKLAISREANSKADPSLN-----PEQLKKLQDKIEKCKQDVL 202 Query: 5901 KYKEKYEKERGKPMLDFETPTYITAKES--QQMQSGKEYRKDYEESIKGRNLTGLEVTPA 5958 K KEKYEK + LD TP Y+ E +Q Q +E R + + LEV Sbjct: 203 KTKEKYEKSLKE--LDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVL------LEVQKH 254 Query: 5959 LLHVKYATKIASEKEYRKDLEESIRGKGLTE 5989 L + +A K DLE+SIR E Sbjct: 255 L----DLSNVAGYKAIYHDLEQSIRAADAVE 281 >gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo sapiens] Length = 661 Score = 53.5 bits (127), Expect = 7e-06 Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 43/212 (20%) Query: 6499 RVWRTNPGSVFDYDPAE---------------DNIQSRSLHMINVQAQRRS---REQSRS 6540 R +R+ P S+F+Y+P + D +Q S + N + +S R R Sbjct: 272 RKFRSEPRSIFEYEPGKSSILQHERPPPKKPLDYVQDHSSGVFNEASLYQSSIDRSLERP 331 Query: 6541 ASALSISGGEEKSEHSEAP--------DHHLSTYSDGGV------------FAVST--AY 6578 S+ S++ K SE D S S G V F S+ + Sbjct: 332 MSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSP 391 Query: 6579 KHAKTTELPQQRSSSVATQ-QTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAI 6637 AK E P+ SS++ ++ P +A+YD+ A + E+SFK GD + Sbjct: 392 SRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTV 451 Query: 6638 INVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 ++ ID+ W G + GR G+ P +YVE + Sbjct: 452 YILRKIDQNWYEG--EHHGRVGIFPISYVEKL 481 Score = 50.1 bits (118), Expect = 8e-05 Identities = 21/58 (36%), Positives = 35/58 (60%) Query: 6612 GKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 G+ F+A+Y+Y + DE+ ++ D I ++ D+GW GT +RT G P NYV+ + Sbjct: 604 GEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 661 Score = 46.6 bits (109), Expect = 8e-04 Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Query: 6605 PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN 6664 P+ P G+ A Y++ A E+S + GD +I ++ +D+ W G + T R G+ P + Sbjct: 495 PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVS 553 Query: 6665 YVEAI 6669 YVE + Sbjct: 554 YVEVV 558 >gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo sapiens] Length = 1151 Score = 53.1 bits (126), Expect = 9e-06 Identities = 26/79 (32%), Positives = 42/79 (53%) Query: 6591 SSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYG 6650 S QQ V+ S S ++A+Y Y+ + DE+ +DGD + ++ D+GW G Sbjct: 1071 SQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVG 1130 Query: 6651 TVQRTGRTGMLPANYVEAI 6669 T +RT + G P NYV+ + Sbjct: 1131 TSRRTKQFGTFPGNYVKPL 1149 Score = 40.0 bits (92), Expect = 0.078 Identities = 17/53 (32%), Positives = 29/53 (54%) Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 A +++ E+SF+ G+ I ++ +DE W G + T R G+ P YV+ I Sbjct: 896 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 948 Score = 37.7 bits (86), Expect = 0.39 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 6616 RAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 RA +D+ A E+ + GD + + ID+ W G + GR G+ P Y+E + Sbjct: 821 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 872 >gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo sapiens] Length = 1292 Score = 53.1 bits (126), Expect = 9e-06 Identities = 26/79 (32%), Positives = 42/79 (53%) Query: 6591 SSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYG 6650 S QQ V+ S S ++A+Y Y+ + DE+ +DGD + ++ D+GW G Sbjct: 1212 SQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVG 1271 Query: 6651 TVQRTGRTGMLPANYVEAI 6669 T +RT + G P NYV+ + Sbjct: 1272 TSRRTKQFGTFPGNYVKPL 1290 Score = 40.0 bits (92), Expect = 0.078 Identities = 17/53 (32%), Positives = 29/53 (54%) Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 A +++ E+SF+ G+ I ++ +DE W G + T R G+ P YV+ I Sbjct: 874 AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 926 Score = 37.7 bits (86), Expect = 0.39 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 6616 RAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669 RA +D+ A E+ + GD + + ID+ W G + GR G+ P Y+E + Sbjct: 799 RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 850 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 53.1 bits (126), Expect = 9e-06 Identities = 104/478 (21%), Positives = 197/478 (41%), Gaps = 50/478 (10%) Query: 5653 KDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSD-TNYKKKFVKEKGKSNYSIMLEPPEV 5711 KD KK GSY T PE++ V K ++ +D T K E+ K + S PE Sbjct: 129 KDSKKKG---GSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPES 185 Query: 5712 KHAMEVAK--KQSDVAYRKDAKE-NLHYTTVADRP--DIKKATQAAKQASEVEYRAKHRK 5766 +++ V+K Q D K++K+ N + + P D+K++ + SE+ Sbjct: 186 QNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEI---CSENS 242 Query: 5767 EGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKG-KTPKYNPKDSQLYKVMKDANN 5825 L ++G+ D E A L + Y +N K K KY KD++ K K +++ Sbjct: 243 LNVDFLMLVGQSDDESINFDAWLRN---YSQNNSKNYSLKYTKYTKKDTK--KNAKKSSD 297 Query: 5826 LASE--VKYKADLKKLHKPV--TDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTI 5881 SE K D KK+ K V D K+ + + ++ S +K +K K Sbjct: 298 AESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKD 357 Query: 5882 PDNLEQLHLKEATELQS------------IVKYKEKYEKERGKPMLDFETPTYITAKESQ 5929 + E+T+ +S + K + +K++ + F T + + + Sbjct: 358 DKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKE 417 Query: 5930 QMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIA--SEKEYRKDLEESIRGKGL 5987 + K+ +KD + K E T A K +K EK+ +KD ++ + K Sbjct: 418 SQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDA 477 Query: 5988 ------TEMEDTPDMLRAKNATQIL--NEKEYKRDLELEVKGRGLNAMANETPDF---MR 6036 TEME ++ + K ++ ++K+ K+D + + + F + Sbjct: 478 KKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTK 537 Query: 6037 ARNATDIASQIKYKQSA--EMEKANFTSVVDTPEIIHAQQVKNLSSQK-KYKEDAEKS 6091 + + + + YK A ++++++ TS E + +++ +SS+K + E EK+ Sbjct: 538 IKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKA 595 Score = 38.1 bits (87), Expect = 0.30 Identities = 93/438 (21%), Positives = 162/438 (36%), Gaps = 44/438 (10%) Query: 69 RKVIRKKVDPSKFMTPYIAHSQKMQDLFSPNKYKEKF--EKTKGQPYASTTDTPELRRIK 126 +K KK K TP S+K ++ N ++ EKTK Q A T + Sbjct: 111 KKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENE 170 Query: 127 KVQDQLSEVKYRMDGDVAKTI---CHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKY 183 + + S + + +KT+ C +K KD +++KK + ++ L+ +N KD Sbjct: 171 QSKKSKSSSETNPESQNSKTVSKNCSQKDK-KDSKNSKKTN---TEFLHTKN-NPKKDLK 225 Query: 184 LLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQK---ALSDV 240 + + ++ L D+S+ N LR +Q +L Sbjct: 226 RSKTSNDPISEICSENSLNVDFLMLVGQSDDESI----NFDAWLRNYSQNNSKNYSLKYT 281 Query: 241 AYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANA 300 Y K ++ A+ + A+ D + AKK + +V K K+D + +K T + Sbjct: 282 KYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSK 341 Query: 301 RMNADNISTRKYQEDFENMKDQIYFMQ---TETPEYKMNKKAGVAASKVKYKEDYEKNKG 357 D +K + + KD + + TE+ + K + K +D +K+ Sbjct: 342 DERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAK 401 Query: 358 KADYNVLPASE----NPQLRQLKAAGDALSD--KLYKENYEKTKAKSINYCETPKFKLD- 410 K ++ SE Q + K D+ +D K K + E T A S ++ K K D Sbjct: 402 KITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDE 461 Query: 411 --------------TVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDK 456 +N S + D LK H S E +K A+ + Sbjct: 462 KKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH---SKEKKGSKKDIKKDARKDTE 518 Query: 457 NYKAEYEEDRGKGFFPQT 474 + AE++E GF T Sbjct: 519 STDAEFDESSKTGFKTST 536 Score = 34.7 bits (78), Expect = 3.3 Identities = 78/412 (18%), Positives = 142/412 (34%), Gaps = 51/412 (12%) Query: 5780 IEMAKKAAKLSSQVKYRENFDK--EKGKTPKYNPKDSQLYKVMKDANNLASEVK-----Y 5832 I +++ + K +Q + F K ++G K P SQ+ D L K Sbjct: 18 IPISESSRKSWNQKHFALTFPKPLQRGTNDKSRPLKSQITVTRHDKRKLEEGQKPAHKWI 77 Query: 5833 KADLKKLHK--PV-TDMKESLIMNHVLNTSQLASSYQYKKKYE------------KSKGH 5877 + +K+ + P+ T +E H+ + +YKK + K G Sbjct: 78 RHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGGS 137 Query: 5878 YHTIPDNLEQLHLKEATELQSI-VKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKE 5936 Y T P++ + + K + ++ K +E E+ K +++ + + Q+ K Sbjct: 138 YATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKS-------SSETNPESQNSKT 190 Query: 5937 YRKDYEESIKGRNLTGLEVTPALLHVKYATK---------------IASEKEYRKDLEES 5981 K+ + K + + LH K K I SE D Sbjct: 191 VSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLML 250 Query: 5982 IRGKGLTEMEDTPDMLRAKNATQILNEK-EYKRDLELEVKGRGLNAMANETPDFMRARNA 6040 + G+ E + LR + N +Y + + + K + E+ D A+ Sbjct: 251 V-GQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKD 309 Query: 6041 TDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKY--KEDAEKSMSYYETV 6098 + + K + + T D + K+ KK K+D +K Y Sbjct: 310 SKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPES 369 Query: 6099 LDTP--EIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKN 6148 DT + + R + +N D K KIT D+ L KE+QK+ Sbjct: 370 TDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKD 421 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.130 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 242,161,294 Number of Sequences: 37866 Number of extensions: 10725178 Number of successful extensions: 35734 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 82 Number of HSP's successfully gapped in prelim test: 264 Number of HSP's that attempted gapping in prelim test: 22078 Number of HSP's gapped (non-prelim): 1892 length of query: 6669 length of database: 18,247,518 effective HSP length: 126 effective length of query: 6543 effective length of database: 13,476,402 effective search space: 88176098286 effective search space used: 88176098286 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 74 (33.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.