Guide to the Human Genome
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Search of human proteins with 115527120

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115527120 nebulin [Homo sapiens]
         (6669 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115527120 nebulin [Homo sapiens]                                  1.354e+04   0.0  
gi|46049105 nebulin-related anchoring protein isoform S [Homo sa...  1189   0.0  
gi|46049092 nebulin-related anchoring protein isoform C [Homo sa...  1176   0.0  
gi|5453758 nebulette sarcomeric isoform [Homo sapiens]                631   e-180
gi|169217576 PREDICTED: similar to nebulin [Homo sapiens]             503   e-141
gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]             253   3e-66
gi|5453710 LIM and SH3 protein 1 [Homo sapiens]                       123   5e-27
gi|47087157 nebulette non-muscle isoform [Homo sapiens]               102   1e-20
gi|20357552 cortactin isoform a [Homo sapiens]                         64   7e-09
gi|20357556 cortactin isoform b [Homo sapiens]                         64   7e-09
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ...    60   7e-08
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ...    60   7e-08
gi|19224660 protein kinase C and casein kinase substrate in neur...    59   2e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     58   4e-07
gi|171906575 drebrin-like isoform c [Homo sapiens]                     56   1e-06
gi|62198235 drebrin-like isoform b [Homo sapiens]                      56   1e-06
gi|21361670 drebrin-like isoform a [Homo sapiens]                      56   1e-06
gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo ...    55   2e-06
gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo s...    55   2e-06
gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo s...    55   3e-06
gi|24308229 protein kinase C and casein kinase substrate in neur...    54   4e-06
gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo s...    54   5e-06
gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo s...    54   5e-06
gi|7661700 sorbin and SH3 domain containing 1 isoform 2 [Homo sa...    54   5e-06
gi|78000160 sorbin and SH3 domain containing 1 isoform 1 [Homo s...    54   5e-06
gi|148747351 protein kinase C and casein kinase substrate in neu...    54   5e-06
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ...    54   7e-06
gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo s...    53   9e-06
gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo s...    53   9e-06
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    53   9e-06

>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 1.354e+04 bits (35143), Expect = 0.0
 Identities = 6669/6669 (100%), Positives = 6669/6669 (100%)

Query: 1    MADDEDYEEVVEYYTEEVVYEEVPGETITKIYETTTTRTSDYEQSETSKPALAQPALAQP 60
            MADDEDYEEVVEYYTEEVVYEEVPGETITKIYETTTTRTSDYEQSETSKPALAQPALAQP
Sbjct: 1    MADDEDYEEVVEYYTEEVVYEEVPGETITKIYETTTTRTSDYEQSETSKPALAQPALAQP 60

Query: 61   ASAKPVERRKVIRKKVDPSKFMTPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTP 120
            ASAKPVERRKVIRKKVDPSKFMTPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTP
Sbjct: 61   ASAKPVERRKVIRKKVDPSKFMTPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTP 120

Query: 121  ELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTK 180
            ELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTK
Sbjct: 121  ELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTK 180

Query: 181  DKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDV 240
            DKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDV
Sbjct: 181  DKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDV 240

Query: 241  AYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANA 300
            AYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANA
Sbjct: 241  AYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANA 300

Query: 301  RMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKAD 360
            RMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKAD
Sbjct: 301  RMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKAD 360

Query: 361  YNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDK 420
            YNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDK
Sbjct: 361  YNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDK 420

Query: 421  KYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYE 480
            KYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYE
Sbjct: 421  KYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYE 480

Query: 481  AIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIP 540
            AIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIP
Sbjct: 481  AIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIP 540

Query: 541  PDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKD 600
            PDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKD
Sbjct: 541  PDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKD 600

Query: 601  YEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQ 660
            YEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQ
Sbjct: 601  YEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQ 660

Query: 661  LKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQ 720
            LKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQ
Sbjct: 661  LKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQ 720

Query: 721  TITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGE 780
            TITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGE
Sbjct: 721  TITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGE 780

Query: 781  KFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS 840
            KFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS
Sbjct: 781  KFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS 840

Query: 841  DVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDML 900
            DVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDML
Sbjct: 841  DVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDML 900

Query: 901  QVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCG 960
            QVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCG
Sbjct: 901  QVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCG 960

Query: 961  WVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAK 1020
            WVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAK
Sbjct: 961  WVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAK 1020

Query: 1021 GEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAAR 1080
            GEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAAR
Sbjct: 1021 GEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAAR 1080

Query: 1081 QAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTP 1140
            QAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTP
Sbjct: 1081 QAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTP 1140

Query: 1141 HDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWM 1200
            HDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWM
Sbjct: 1141 HDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWM 1200

Query: 1201 KGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL 1260
            KGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL
Sbjct: 1201 KGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL 1260

Query: 1261 YKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAA 1320
            YKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAA
Sbjct: 1261 YKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAA 1320

Query: 1321 KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTS 1380
            KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTS
Sbjct: 1321 KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTS 1380

Query: 1381 YHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEY 1440
            YHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEY
Sbjct: 1381 YHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEY 1440

Query: 1441 NSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQL 1500
            NSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQL
Sbjct: 1441 NSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQL 1500

Query: 1501 SDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIP 1560
            SDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIP
Sbjct: 1501 SDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIP 1560

Query: 1561 IVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEA 1620
            IVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEA
Sbjct: 1561 IVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEA 1620

Query: 1621 SKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLY 1680
            SKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLY
Sbjct: 1621 SKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLY 1680

Query: 1681 KSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSN 1740
            KSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSN
Sbjct: 1681 KSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSN 1740

Query: 1741 KLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRP 1800
            KLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRP
Sbjct: 1741 KLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRP 1800

Query: 1801 DAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKK 1860
            DAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKK
Sbjct: 1801 DAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKK 1860

Query: 1861 GYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQS 1920
            GYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQS
Sbjct: 1861 GYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQS 1920

Query: 1921 DNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVL 1980
            DNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVL
Sbjct: 1921 DNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVL 1980

Query: 1981 AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGY 2040
            AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGY
Sbjct: 1981 AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGY 2040

Query: 2041 DLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDR 2100
            DLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDR
Sbjct: 2041 DLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDR 2100

Query: 2101 EYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMN 2160
            EYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMN
Sbjct: 2101 EYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMN 2160

Query: 2161 RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM 2220
            RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM
Sbjct: 2161 RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM 2220

Query: 2221 DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL 2280
            DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL
Sbjct: 2221 DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL 2280

Query: 2281 KKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKM 2340
            KKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKM
Sbjct: 2281 KKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKM 2340

Query: 2341 QSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQA 2400
            QSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQA
Sbjct: 2341 QSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQA 2400

Query: 2401 KKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIP 2460
            KKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIP
Sbjct: 2401 KKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIP 2460

Query: 2461 DAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYE 2520
            DAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYE
Sbjct: 2461 DAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYE 2520

Query: 2521 ELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHV 2580
            ELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHV
Sbjct: 2521 ELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHV 2580

Query: 2581 AKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDV 2640
            AKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDV
Sbjct: 2581 AKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDV 2640

Query: 2641 IHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFS 2700
            IHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFS
Sbjct: 2641 IHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFS 2700

Query: 2701 SLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKL 2760
            SLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKL
Sbjct: 2701 SLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKL 2760

Query: 2761 GLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWS 2820
            GLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWS
Sbjct: 2761 GLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWS 2820

Query: 2821 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ 2880
            MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ
Sbjct: 2821 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ 2880

Query: 2881 SDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRF 2940
            SDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRF
Sbjct: 2881 SDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRF 2940

Query: 2941 KFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETL 3000
            KFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETL
Sbjct: 2941 KFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETL 3000

Query: 3001 YKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKM 3060
            YKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKM
Sbjct: 3001 YKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKM 3060

Query: 3061 MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCL 3120
            MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCL
Sbjct: 3061 MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCL 3120

Query: 3121 PDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPP 3180
            PDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPP
Sbjct: 3121 PDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPP 3180

Query: 3181 DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYS 3240
            DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYS
Sbjct: 3181 DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYS 3240

Query: 3241 ESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDD 3300
            ESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDD
Sbjct: 3241 ESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDD 3300

Query: 3301 PKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEW 3360
            PKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEW
Sbjct: 3301 PKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEW 3360

Query: 3361 ICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYR 3420
            ICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYR
Sbjct: 3361 ICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYR 3420

Query: 3421 QRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRI 3480
            QRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRI
Sbjct: 3421 QRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRI 3480

Query: 3481 NYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNI 3540
            NYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNI
Sbjct: 3481 NYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNI 3540

Query: 3541 KDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPL 3600
            KDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPL
Sbjct: 3541 KDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPL 3600

Query: 3601 HEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDR 3660
            HEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDR
Sbjct: 3601 HEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDR 3660

Query: 3661 KYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKS 3720
            KYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKS
Sbjct: 3661 KYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKS 3720

Query: 3721 NSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGA 3780
            NSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGA
Sbjct: 3721 NSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGA 3780

Query: 3781 QSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYR 3840
            QSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYR
Sbjct: 3781 QSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYR 3840

Query: 3841 NYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIF 3900
            NYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIF
Sbjct: 3841 NYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIF 3900

Query: 3901 CDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINL 3960
            CDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINL
Sbjct: 3901 CDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINL 3960

Query: 3961 ARANALNVSNKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYV 4020
            ARANALNVSNKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYV
Sbjct: 3961 ARANALNVSNKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYV 4020

Query: 4021 GTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMD 4080
            GTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMD
Sbjct: 4021 GTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMD 4080

Query: 4081 YRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAAD 4140
            YRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAAD
Sbjct: 4081 YRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAAD 4140

Query: 4141 IFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLH 4200
            IFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLH
Sbjct: 4141 IFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLH 4200

Query: 4201 TAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGH 4260
            TAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGH
Sbjct: 4201 TAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGH 4260

Query: 4261 YVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSD 4320
            YVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSD
Sbjct: 4261 YVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSD 4320

Query: 4321 IDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKN 4380
            IDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKN
Sbjct: 4321 IDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKN 4380

Query: 4381 QEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPD 4440
            QEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPD
Sbjct: 4381 QEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPD 4440

Query: 4441 TPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYE 4500
            TPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYE
Sbjct: 4441 TPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYE 4500

Query: 4501 KQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQ 4560
            KQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQ
Sbjct: 4501 KQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQ 4560

Query: 4561 YILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQIL 4620
            YILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQIL
Sbjct: 4561 YILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQIL 4620

Query: 4621 HAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKY 4680
            HAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKY
Sbjct: 4621 HAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKY 4680

Query: 4681 TTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKY 4740
            TTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKY
Sbjct: 4681 TTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKY 4740

Query: 4741 REEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVT 4800
            REEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVT
Sbjct: 4741 REEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVT 4800

Query: 4801 AKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWD 4860
            AKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWD
Sbjct: 4801 AKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWD 4860

Query: 4861 TPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVH 4920
            TPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVH
Sbjct: 4861 TPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVH 4920

Query: 4921 SVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMS 4980
            SVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMS
Sbjct: 4921 SVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMS 4980

Query: 4981 SYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPE 5040
            SYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPE
Sbjct: 4981 SYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPE 5040

Query: 5041 IRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKG 5100
            IRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKG
Sbjct: 5041 IRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKG 5100

Query: 5101 FGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELV 5160
            FGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELV
Sbjct: 5101 FGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELV 5160

Query: 5161 YRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAK 5220
            YRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAK
Sbjct: 5161 YRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAK 5220

Query: 5221 DVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTV 5280
            DVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTV
Sbjct: 5221 DVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTV 5280

Query: 5281 KDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDL 5340
            KDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDL
Sbjct: 5281 KDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDL 5340

Query: 5341 TWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQL 5400
            TWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQL
Sbjct: 5341 TWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQL 5400

Query: 5401 MNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPE 5460
            MNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPE
Sbjct: 5401 MNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPE 5460

Query: 5461 HLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNK 5520
            HLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNK
Sbjct: 5461 HLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNK 5520

Query: 5521 SNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDF 5580
            SNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDF
Sbjct: 5521 SNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDF 5580

Query: 5581 EYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLA 5640
            EYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLA
Sbjct: 5581 EYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLA 5640

Query: 5641 KTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKS 5700
            KTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKS
Sbjct: 5641 KTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKS 5700

Query: 5701 NYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEY 5760
            NYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEY
Sbjct: 5701 NYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEY 5760

Query: 5761 RAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVM 5820
            RAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVM
Sbjct: 5761 RAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVM 5820

Query: 5821 KDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHT 5880
            KDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHT
Sbjct: 5821 KDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHT 5880

Query: 5881 IPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKD 5940
            IPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKD
Sbjct: 5881 IPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKD 5940

Query: 5941 YEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAK 6000
            YEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAK
Sbjct: 5941 YEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAK 6000

Query: 6001 NATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANF 6060
            NATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANF
Sbjct: 6001 NATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANF 6060

Query: 6061 TSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQ 6120
            TSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQ
Sbjct: 6061 TSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQ 6120

Query: 6121 CDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMMRVKQTQDHI 6180
            CDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMMRVKQTQDHI
Sbjct: 6121 CDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMMRVKQTQDHI 6180

Query: 6181 SSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTPEIERVKRNQE 6240
            SSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTPEIERVKRNQE
Sbjct: 6181 SSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTPEIERVKRNQE 6240

Query: 6241 NFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENMGKGTPLAVTPEMERVKHN 6300
            NFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENMGKGTPLAVTPEMERVKHN
Sbjct: 6241 NFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENMGKGTPLAVTPEMERVKHN 6300

Query: 6301 QENISSVLYKENVGKATATPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVK 6360
            QENISSVLYKENVGKATATPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVK
Sbjct: 6301 QENISSVLYKENVGKATATPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVK 6360

Query: 6361 RNQENFSSVLYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDT 6420
            RNQENFSSVLYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDT
Sbjct: 6361 RNQENFSSVLYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDT 6420

Query: 6421 PEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYRGIQRKV 6480
            PEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYRGIQRKV
Sbjct: 6421 PEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYRGIQRKV 6480

Query: 6481 VEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSREQSRS 6540
            VEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSREQSRS
Sbjct: 6481 VEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSREQSRS 6540

Query: 6541 ASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTT 6600
            ASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTT
Sbjct: 6541 ASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTT 6600

Query: 6601 VSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGM 6660
            VSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGM
Sbjct: 6601 VSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGM 6660

Query: 6661 LPANYVEAI 6669
            LPANYVEAI
Sbjct: 6661 LPANYVEAI 6669


>gi|46049105 nebulin-related anchoring protein isoform S [Homo
            sapiens]
          Length = 1730

 Score = 1189 bits (3075), Expect = 0.0
 Identities = 619/1546 (40%), Positives = 974/1546 (63%), Gaps = 55/1546 (3%)

Query: 456  KNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHT-YKVHPDK--TKFTQVTDSPVLL 512
            + Y  +YE+ RGKG FP  IT  Y+  KK +Q      YK   D+  ++F+ V D+P LL
Sbjct: 155  EEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELL 214

Query: 513  QAQVNSKQLSDLNYKAKHESEKFKCHIPPD-TPAFIQHKVNAYNLSDNLYKQDWEKSKAK 571
            +++  ++  SD+ Y   +E ++ K   P   TPA+   K      SD  Y Q ++K    
Sbjct: 215  RSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRG 274

Query: 572  KFDIKVDAIPLLA----------------------------------AKANTKNTSDVMY 597
                 + A  +L                                   AK   +  SD+ Y
Sbjct: 275  MAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKY 334

Query: 598  KKDYEKNKGKM-IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQ 656
            ++D+ K KG      L   D+  +  +  V K  S+  YK++ E ++  S+NYCETP+++
Sbjct: 335  RQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFR 394

Query: 657  LDTQLKNF-SEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGK 715
              +++  F S+ +YK+ Y   + G Y G   D    H MKV +  S+ +YKA+Y+ D   
Sbjct: 395  NVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVD 454

Query: 716  CYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKA 775
              +P T+T  Y+   KL   KD  Y+   DK K+++VTD+P ++QA++N +QLS +NY+A
Sbjct: 455  YNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRA 514

Query: 776  KHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKAN 835
             +E  K    +P D PQ ++ + NA   S+  YK+ WEK+K K F++K+DA+ LLAAKA+
Sbjct: 515  DYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKAS 574

Query: 836  TKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTA 895
             +  S++ YK++YEK+KGK +G      D ++LHSL+ AK  S+ EY+K +E+SKT +  
Sbjct: 575  GELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHL 630

Query: 896  PLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSW 955
            P+DM+ +  AKK+Q +ASD+DY+  LH Y+  P+ +    AKKAY LQS+++YKAD  +W
Sbjct: 631  PMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL-AW 689

Query: 956  MKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDI 1015
            MKG GW+  GSL +E+AK+A  +++EK YRQ  D LKFTS+ D+     +K +Q  +S +
Sbjct: 690  MKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGV 749

Query: 1016 AYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRA 1075
            AYKA  E+ +H+Y +  D P F+QA+ NA N+SE +YK+  ++   KG++LR D++   A
Sbjct: 750  AYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLA 809

Query: 1076 AKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKS 1135
            AKA R  AS+V+YK+DYE+++GK++G + +Q D ++ H + ++K+QS+ EYKK +E TKS
Sbjct: 810  AKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKS 869

Query: 1136 KYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKED 1195
            + +   DM ++V A+KAQ + ++V YK + HH+T LP  M +E +K    +QSDN Y+ D
Sbjct: 870  QCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRAD 929

Query: 1196 YNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQ 1255
               WMKG+GW+  GSL+VE+ KKAG+ ++EKKYRQHPD LKFTSI D+P MVQA+ +  Q
Sbjct: 930  VK-WMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQ 988

Query: 1256 VSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAI 1315
              D LY+ +GE++KH YT + DLP+ L AK NA NIS+  YK  W  L   G  +  DA+
Sbjct: 989  AVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDAL 1048

Query: 1316 PITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYE 1375
            P  AAKAS  I SDYKYKEA+EK KG+ +G RSL+DD  L H +    LQSD  YKK +E
Sbjct: 1049 PFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFE 1108

Query: 1376 NTKTSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNV 1435
            ++K  +H P DM ++  AK AQ +A+N +YK PL  YT L + + L   +  +++QS+N+
Sbjct: 1109 HSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENL 1168

Query: 1436 YKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQH 1495
            Y+ + N F++G+  +  G+LE+E  KKA + ++E KYRQHP + K+T+V D+  ++ A+ 
Sbjct: 1169 YRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKF 1227

Query: 1496 NTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLR 1555
            + +  ++  YK  GE  +H+YT+   LP+FI+AK NA N+SDA YK  W+   A+GY L 
Sbjct: 1228 SNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLT 1287

Query: 1556 PDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYK 1615
             +A+P  AA++S +IASD  Y+  + K +GK +G  S++DDP++ H   + ++QS+ +Y+
Sbjct: 1288 IEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1347

Query: 1616 KGYEASKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQ 1675
            +G  +S+ ++H P+DMV +  AK +Q +A++ +YR  YH +T LP+ L +  ++ A  +Q
Sbjct: 1348 RGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQ 1407

Query: 1676 SDNLYKSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQA 1735
            S+  YKSD    MKGIGW+ + S ++E AKKAGE++SE KYR+ P+ +KFT  +D+ +  
Sbjct: 1408 SELRYKSDLIG-MKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLV 1466

Query: 1736 LNKSNKLNMDKRLYTEKWNKDKTTIH---VMPDTPDILLSRVNQITMSDKLYKAGWEEEK 1792
              K++ ++ ++R+Y    + D  ++H   ++PD PD   +R+N + +SDK+Y+  WE+ +
Sbjct: 1467 HAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTR 1523

Query: 1793 KKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKM 1852
               YD R DAI  + ARASR+IASD++YK+A+ + +G  IG+RS++DDP++ HF+ V ++
Sbjct: 1524 AGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRL 1583

Query: 1853 QSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELA 1912
            QSD EYKK + KS++ FH+  D   ++ AK+SQ++A++ +YR  +      P+ +    A
Sbjct: 1584 QSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHA 1643

Query: 1913 KNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEK 1958
            +   Q+QSD +YK+D  +  +G+GW P GS + E  ++A E+ + +
Sbjct: 1644 QKAHQLQSDVKYKSD-LNLTRGVGWTPPGSYKVEMARRAAELANAR 1688



 Score = 1135 bits (2936), Expect = 0.0
 Identities = 619/1646 (37%), Positives = 983/1646 (59%), Gaps = 57/1646 (3%)

Query: 109  KGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVS 168
            K   + S   TP    ++   + +S +  + DG+  K++ H D K+KD E A       +
Sbjct: 60   KNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLAN 119

Query: 169  KVLYKQNWEDTKDKYLLPPDA---PELVQAVKNTAMFSKKLYTEDWEADKSL-FYPYNDS 224
            +  Y   W    +     P A   PE+V+ V+      ++ YTED+E  +    +P   +
Sbjct: 120  ERAY---WTGYGEGNAWCPGALPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMIT 175

Query: 225  PELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENK 284
            P  +R  +A +  S V YK+G  E+ ++F+ + D P++  +K      S  +Y EDYE +
Sbjct: 176  PAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQ 235

Query: 285  IKGKWSE----TPCFEVANAR------------------------MNADNISTRK----- 311
             +GK S     TP +++A                           + A+ I TR+     
Sbjct: 236  -RGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294

Query: 312  ---YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASE 368
               Y E++E  + +  F    TP Y+  KKA   AS +KY++D+ K KG A Y+ LPA +
Sbjct: 295  GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQD 354

Query: 369  NPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLK 428
            N  L+Q ++    +S+  YK++ E ++  SINYCETP+F+  + +  F+SD KYK++Y  
Sbjct: 355  NLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQN 414

Query: 429  DILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQC 488
             + G Y G   D    H MKV +  S+  YKA+Y+ D     +P T+T  Y+   KL   
Sbjct: 415  HMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPL 474

Query: 489  KDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQ 548
            KD  Y+   DK K++ VTD+P ++QA++N++QLS +NY+A +E  K    +P D P  ++
Sbjct: 475  KDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVK 534

Query: 549  HKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKM 608
             K NA   S+  YK+ WEK+K K F++K+DA+ LLAAKA+ +  S++ YK++YEK KGK 
Sbjct: 535  AKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA 594

Query: 609  IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEAR 668
            +G      D ++LHSL++AK  S+  YK+ +E++K +       P   ++ +    ++  
Sbjct: 595  MGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR----FHLPMDMVNIRHAKKAQTL 646

Query: 669  YKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEA 728
              DL  +  L  Y    ED       K     S+  YKA+    KG  +  +      +A
Sbjct: 647  ASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQA 706

Query: 729  IKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPA 788
             K      +  Y+   D+ KFT+VTDS  +  A+ + +  S + YKA +E    +  I  
Sbjct: 707  KKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISK 766

Query: 789  DAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDY 848
            D P F+Q R NA NLS+ +YK  WE  KAK F++++D++  LAAKA     S+V YK+DY
Sbjct: 767  DEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDY 826

Query: 849  EKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKS 908
            E+S+GK+IGA  +  D +M HSL+ +K QS+ EY+K +E +K+     LDM+ +  A+K+
Sbjct: 827  ERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKA 886

Query: 909  QAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLE 968
            Q +A+DV YK   H ++  P  + V+ AKKAY LQSD +Y+AD   WMKG GWV  GSL 
Sbjct: 887  QHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLN 945

Query: 969  MEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKY 1028
            +E+AK+A ++++EKKYRQHPD LKFTSI+D P  VQ++I+  Q  D  Y+ +GE I H Y
Sbjct: 946  VEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHY 1005

Query: 1029 NLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQY 1088
                DLP+ + AK+NA NISE  YK     L   GY LR DA+P +AAKA+ +  SD +Y
Sbjct: 1006 TPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKY 1065

Query: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA 1148
            K+ +EK KG+M+G +SL+DD  L H +    +QSD  YKK +E +K++++ P DM  +V 
Sbjct: 1066 KEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVH 1125

Query: 1149 AKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPI 1208
            AKKAQ + SN +YKH L  YT L + + L  +K   ++QS+N+Y+ D  N+M+G+  +  
Sbjct: 1126 AKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL-NFMRGVACVIP 1184

Query: 1209 GSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDV 1268
            G+L++E  KKA + ++E KYRQHP + K+T++ D+P ++ AK + +  ++ LYKA GED 
Sbjct: 1185 GTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDA 1244

Query: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328
            +H+YTM+  LP+F++AK NA N+SD  YK  W +L A+G  +  +A+P  AA+AS +IAS
Sbjct: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304

Query: 1329 DYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV 1388
            D+ Y+  + K +GK +G +S++DDP++ H   + +LQS+ +Y++   +++  +H P DMV
Sbjct: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMV 1364

Query: 1389 SITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIG 1448
             +  AK AQ +A++ +Y+   H +T LP+ + +   +  + +QS+  YK +    +KGIG
Sbjct: 1365 HLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIG 1423

Query: 1449 WIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVE 1508
            W+ + S ++E  KKAG+ ++E KYR+ PD++KFT+V DS  +V A+++    ++  Y+  
Sbjct: 1424 WLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSG 1483

Query: 1509 GEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSR 1568
              +  H+YT+ P+ P F +A++NAL++SD  Y+  W++T A  YD R DAIP   A++SR
Sbjct: 1484 DAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASR 1543

Query: 1569 NIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTP 1628
             IASD +YKEA+ + +G Q+G+ S+ DDP++ H++NV ++QSD EYKK +  S++++H+ 
Sbjct: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1603

Query: 1629 LDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWM 1688
             D   +  AK+SQ++A++ +YRQ     T  P+ L + H++ A Q+QSD  YKSD  N  
Sbjct: 1604 TDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDL-NLT 1662

Query: 1689 KGIGWVPIESLEVEKAKKAGEILSEK 1714
            +G+GW P  S +VE A++A E+ + +
Sbjct: 1663 RGVGWTPPGSYKVEMARRAAELANAR 1688



 Score = 1038 bits (2683), Expect = 0.0
 Identities = 592/1602 (36%), Positives = 935/1602 (58%), Gaps = 82/1602 (5%)

Query: 1108 DPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA-AKKAQDVVSNVNYKHS-- 1164
            DP++V  +   K   + EY +DYE+ + K + P  +      AKKA  + S V YK    
Sbjct: 140  DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198

Query: 1165 --LHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDA 1222
              +  ++ + D  +L  SK   Q+QSD  Y EDY    +G G  P       ++ K  + 
Sbjct: 199  ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ-QRGKGSFPAMITPAYQIAKRANE 257

Query: 1223 LNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL---YKAKGEDVKHKYTMSPDL- 1278
            L     R H    K    +  P +      T++ +D     Y  + E+ + K +    + 
Sbjct: 258  L-ASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMIT 316

Query: 1279 PQFLQAKCNAYNISDVCYKRD---------WHDLIAKGNNVLGDAIPITAAKASRNIASD 1329
            P +  AK      SD+ Y++D         +H L A+ N VL  A      ++   + S+
Sbjct: 317  PAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQA------QSVNKLVSE 370

Query: 1330 YKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYEN-TKTSYHTPG-DM 1387
             +YK+  E S+G  + +    + P+  +   ++K  SD +YK+NY+N  +  Y   G D 
Sbjct: 371  VEYKKDLESSRGHSINYC---ETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDR 427

Query: 1388 VSITAAK---MAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFL 1444
             ++ A K   +A +VA   +YK  +  Y Y P  ++                   Y + +
Sbjct: 428  RTLHAMKVGSLASNVAYKADYKHDIVDYNY-PATLT-----------------PSYQTAM 469

Query: 1445 KGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLN 1504
            K +                   L +  YRQ  D +K++SV D+  +V A+ N +QLS +N
Sbjct: 470  KLV------------------PLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVN 511

Query: 1505 YKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAA 1564
            Y+ + EK K  YT+  ++PQ ++AK NA   S+  YK  W+KT  KG++++ DA+ ++AA
Sbjct: 512  YRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 571

Query: 1565 KSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK 1624
            K+S  +AS+ KYKE YEK KGK +G      D +L+H + +AK+ S+ EYKKG+E SKT+
Sbjct: 572  KASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR 627

Query: 1625 YHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDF 1684
            +H P+DMV++  AKK+Q +A++ +YR+  H YT+LP+ +  + ++ A  +QS+  YK+D 
Sbjct: 628  FHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL 687

Query: 1685 TNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNM 1744
              WMKG+GW+   SL +E+AKKAG+++SEK YRQ  ++LKFT   D+ +    K ++   
Sbjct: 688  A-WMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQ 746

Query: 1745 DKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIA 1804
                Y     +      +  D P  L +R N   +S+KLYK+ WE +K KG++LR D++ 
Sbjct: 747  SGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLT 806

Query: 1805 IKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEK 1864
              AA+A RD+AS+ KYK+ YE+++GK IG + ++ D ++ H +Q++K+QS+ EYKKG+E 
Sbjct: 807  FLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFED 866

Query: 1865 SKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQY 1924
            +K+  H  +DM+ +V A+K+Q +AT+  Y+   H +  LP  M  E AK    +QSDNQY
Sbjct: 867  TKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQY 926

Query: 1925 KADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNN 1984
            +AD   +MKG+GW+  GSL  E+ KKA E+ISEKKYRQHPD LK++++ D+  MV A+ +
Sbjct: 927  RAD-VKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARIS 985

Query: 1985 AKIMNEHLYKQAWEADKTKVHIMP--DIPQIILAKANAINMSDKLYKLSLEESKKKGYDL 2042
                 + LY++  + +  K H  P  D+P+++LAK NA+N+S+  YK S  + +  GY L
Sbjct: 986  YTQAVDRLYRE--QGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKL 1043

Query: 2043 RPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREY 2102
            R DA+P +AAKAS +I SDYKYK  +EK KG+M+G RSLEDD  L HS+    +QSD  Y
Sbjct: 1044 RLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNY 1103

Query: 2103 KKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRI 2162
            KK +E++K  +H P DM ++  AK AQ   +N +YKH + +Y  L + + +   +  +++
Sbjct: 1104 KKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKL 1163

Query: 2163 QSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDM 2222
            QS+N Y+ D N + +G+     G+LE+E  KKA+E  S+ KYRQHP +F++  +TD+ ++
Sbjct: 1164 QSENLYRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNL 1222

Query: 2223 VLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKK 2282
            + AK +    N+ LY       + +  +    P+ ++AK N    S   YK  W     +
Sbjct: 1223 LHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQ 1282

Query: 2283 GYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQS 2342
            GY L ++A+  Q A+AS DIASD+ Y+  + K+ G  +G +S++DDP++     + ++QS
Sbjct: 1283 GYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQS 1342

Query: 2343 EREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKK 2402
            E +Y++     + +F  P+DM+ +V AK  Q L SD DY+   H++T LP+   +  AKK
Sbjct: 1343 ELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKK 1402

Query: 2403 VYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDA 2462
             + LQSE  YKSDL  ++GIGW  L S + E  K+A E+ISE KYR+ PD  KFT++ D+
Sbjct: 1403 AHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDS 1462

Query: 2463 MDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEEL 2522
             D+V AK +  + ++R+YR    +   +  ++PD PD   A+ N ++ SDK+YR  +E+ 
Sbjct: 1463 PDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQT 1522

Query: 2523 KRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAK 2582
            +   YD  +DAIP + A+ASREIAS+++YKE F +  G  IG R+++DDP+M   ++V +
Sbjct: 1523 RAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGR 1582

Query: 2583 IQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIH 2642
            +QSD EYKKDF K +++F S  D  G++ AK+ Q L SDV Y+  L Q TC P+Q  + H
Sbjct: 1583 LQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRH 1642

Query: 2643 ARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQI 2684
            A++A+ LQSD  YKSDL   +G+GW   GS + E  +RA ++
Sbjct: 1643 AQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1684



 Score = 1022 bits (2642), Expect = 0.0
 Identities = 603/1626 (37%), Positives = 937/1626 (57%), Gaps = 61/1626 (3%)

Query: 2050 KAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENT 2109
            + A   + +A++  Y   Y +G     G      DP++V  ++  K   + EY ++YE  
Sbjct: 109  EGAPNRQPLANERAYWTGYGEGNAWCPGALP---DPEIVRMVEARKSLGE-EYTEDYEQP 164

Query: 2110 KTSYHTPADML-SVTAAKDAQANITNTNYKH----LIHKYILLPDAMNIELTRNMNRIQS 2164
            +     PA +  +   AK A    +   YK      I ++  + D   +  ++   ++QS
Sbjct: 165  RGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQS 224

Query: 2165 DNEYKQDYNEWYKGLGWSPAGSLEVEK-AKKATEYASDQKYRQHPSNFQFKKLTDSMDMV 2223
            D  Y +DY E  +G G  PA      + AK+A E ASD +Y Q       K++       
Sbjct: 225  DVRYTEDY-EQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQ----KEMRGMAGPA 279

Query: 2224 LAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKG 2283
            +  +   T                             ++    Y Q  Y   +EE   KG
Sbjct: 280  IGAEGILT-----------------------------RECADQYGQG-YPEEYEEHRGKG 309

Query: 2284 YDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGH-HVGFRSLQDDPKLVLSMNVAKMQS 2342
                +   + Q AK + ++ASD KY+Q + K  G  H      QD+  L  + +V K+ S
Sbjct: 310  SFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369

Query: 2343 EREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYK-NYLH----QWTCLPDQNDV 2397
            E EYKKD E  +    +  +        K  +  SD  YK NY +    ++  +      
Sbjct: 370  EVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRT 429

Query: 2398 VQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFT 2457
            + A KV  L S   YK+D +        P     + +       + +  YRQ  D+ K++
Sbjct: 430  LHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 489

Query: 2458 SIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRM 2517
            S+ D   IV AK NA+  S   YR  ++K+K    +  D P +V AK N    S+  Y+ 
Sbjct: 490  SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 549

Query: 2518 GYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWS 2577
            G+E+ K KG+++ +DA+ + AAKAS E+AS  KYKE + K  G  +G      D +++ S
Sbjct: 550  GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 605

Query: 2578 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ 2637
            + +AK+ S+ EYKK FE+ KT+F  P+DM+ +  AKK QTL SD+DY+  LH++T LP+ 
Sbjct: 606  LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 665

Query: 2638 SDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQF 2697
                 A++AY LQS+  YK+DL W+KG+GW+T GSL  E+ K+A Q++S+  YRQ  D+ 
Sbjct: 666  MKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725

Query: 2698 KFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKL 2757
            KF+S+ DS  M  AK +    +   Y    ++      I  D P  L A+ N  N SEKL
Sbjct: 726  KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785

Query: 2758 YKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKM 2817
            YK   E  K KG+++R+D++   AAKA RD+ASE KYKE Y +  G  IGA+ ++ D +M
Sbjct: 786  YKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQM 845

Query: 2818 MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCL 2877
              S+ ++K+QS+ EYKK FE  K++    +DM+ +V A+K Q L +DV YK   H +T L
Sbjct: 846  SHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905

Query: 2878 PDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPP 2937
            P    V  A++AY LQSDN Y++D++WM+G+GWV+ GSL+VE+ K+A E++S+K YRQ P
Sbjct: 906  PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 965

Query: 2938 DRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYS 2997
            D  KFTS+ D+ E V A+ +      RLY E  +  K       D PE++LA+ N +N S
Sbjct: 966  DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 1025

Query: 2998 ETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDD 3057
            ET YK +  + +  GY LR DA+P  AAKAS ++ISDYKYK+ + K  G  +G+R++EDD
Sbjct: 1026 ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1085

Query: 3058 PKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEW 3117
              +  S++   +QSD  YKK FE  K +F  P+DM  +V AKK QTL S+ DYK+ L ++
Sbjct: 1086 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1145

Query: 3118 TCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYR 3177
            T L +   +  A++A+ LQS+N+Y+SDL ++RG+  V  G++++   K+A+E++S++ YR
Sbjct: 1146 TSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYR 1205

Query: 3178 QPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKI 3237
            Q P   K+T+VTD+   + AK +    N+RLY  A +  + +  +    PE + A+ N  
Sbjct: 1206 QHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAA 1265

Query: 3238 NYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAV 3297
            N S++ Y+++    + +GY L  +A+P  AA+AS DIASD+ Y+  + K+ G  IG ++V
Sbjct: 1266 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSV 1325

Query: 3298 HDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPL 3357
             DDP+I     + ++QS+ +Y++     + ++  P+DM+ +V AK  Q L SD DY+   
Sbjct: 1326 RDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQY 1385

Query: 3358 HEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDT 3417
            H++  LP+   +  A+KA+ LQS+  YKSDL  MKGIGW+ + S ++  AK+AGEL+S+T
Sbjct: 1386 HKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISET 1445

Query: 3418 IYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIH---VMPDTPEIML 3474
             YR++P+++KFT++ D+P+ V AKN+ ++ N+R+Y      D +++H   ++PD P+   
Sbjct: 1446 KYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTR 1502

Query: 3475 AKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHH 3534
            A+LN ++ SDK+Y+ + E+++   YD RLDAIP Q A+ASR+IASD++YKE + +  G  
Sbjct: 1503 ARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQ 1562

Query: 3535 IGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDI 3594
            IG R++ DDP+M   ++V ++QSD EYKK+F K +++F S  D  G++ AK+ Q L SD+
Sbjct: 1563 IGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDV 1622

Query: 3595 DYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAG 3654
             Y+ PL + TC P+Q  +  A+KA+ LQSD  YKSDL   RG+GW P GS +VE  +RA 
Sbjct: 1623 HYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAA 1682

Query: 3655 EILSDR 3660
            E+ + R
Sbjct: 1683 ELANAR 1688



 Score = 1021 bits (2639), Expect = 0.0
 Identities = 589/1588 (37%), Positives = 926/1588 (58%), Gaps = 59/1588 (3%)

Query: 2328 DPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQELVSDVDYKN--- 2383
            DP++V  +   K   E EY +D+E+ + K S P  +      AKK  +L S V+YK    
Sbjct: 140  DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198

Query: 2384 -YLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEK-NKRASEI 2441
              + +++ + D  +++++K   +LQS+  Y  D E  RG G  P     A +  KRA+E+
Sbjct: 199  ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANEL 258

Query: 2442 ISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIV 2501
             S+ +Y Q   +        A+               L RE  D+               
Sbjct: 259  ASDVRYHQQYQKEMRGMAGPAI----------GAEGILTRECADQ--------------- 293

Query: 2502 LAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGH 2561
                       + Y   YEE + KG    +     + AK + E+AS+ KY++ F K  G 
Sbjct: 294  ---------YGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGA 344

Query: 2562 -HIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVS 2620
             H  +   +D+  +  +  V K+ S+ EYKKD E  +    +  +        K     S
Sbjct: 345  AHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTS 404

Query: 2621 DVDYK-NYLH----QWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLED 2675
            D  YK NY +    ++  +      +HA +   L S+  YK+D +    + +    +L  
Sbjct: 405  DNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKH-DIVDYNYPATLTP 463

Query: 2676 EKNKRATQI-LSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTV 2734
                    + L D  YRQ  D+ K+SS+ D+  +V AK NA  ++H  Y   ++K+K   
Sbjct: 464  SYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNY 523

Query: 2735 HIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKY 2794
             +  D P+++ AK N   +SE  YK G E+ K KG++M++DA+ + AAKAS ++AS  KY
Sbjct: 524  TLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKY 583

Query: 2795 KEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL 2854
            KE Y K  G  +G      D +++ S+ +AK+ S+ EYKK FE+ KT+F  P+DM+ +  
Sbjct: 584  KEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRH 639

Query: 2855 AKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIG 2914
            AKK QTL SD+DY+  LH++T LP+      A++AY LQS+  YK+DL WM+G+GW++ G
Sbjct: 640  AKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEG 699

Query: 2915 SLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDK 2974
            SL++E+ K+A +++S+K YRQ  D  KFTSVTDS +   AK +    +   Y    ++  
Sbjct: 700  SLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV 759

Query: 2975 TQIHIMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISD 3034
             Q  I  D P  + AR N  N SE LYK + E  K KG++LR D++  +AAKA RD+ S+
Sbjct: 760  HQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASE 819

Query: 3035 YKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLG 3094
             KYK+ Y +  G  IGA++++ D +M  S+ ++K+QS+ EYKK FE  K++    +DM+ 
Sbjct: 820  VKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVH 879

Query: 3095 VVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWV 3154
            +V A+K Q L +DV YK   H +T LP    V  A++AY LQSDN Y++D++W++G+GWV
Sbjct: 880  LVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWV 939

Query: 3155 PIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWD 3214
              GS++V + K+A E++S+  YRQ PD LKFTS+ D+ E V A+ +      RLY E  +
Sbjct: 940  ATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGE 999

Query: 3215 KDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDI 3274
              K       D PE++LA+ N +N SE+ Y+++  + +  GY LR DA+P  AAKAS +I
Sbjct: 1000 NIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEI 1059

Query: 3275 ASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVD 3334
             SDYKYKEA+ K  G  +G+R++ DD  +  S++   +QSD  YKK FE  K ++  P+D
Sbjct: 1060 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1119

Query: 3335 MLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGI 3394
            M  +V AKK QTL S+ DYKHPL ++  L +   +  A+KA+ LQS+NLY+SDL +M+G+
Sbjct: 1120 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1179

Query: 3395 GWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTE 3454
              V   +LE+   K+A EL+S++ YRQ P + K+T++TDTP  + AK +    N+RLY  
Sbjct: 1180 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKA 1239

Query: 3455 AWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKAS 3514
            A ++ +    +    PE + AK N  N SD  YK +    + +GY L ++A+P QAA+AS
Sbjct: 1240 AGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARAS 1299

Query: 3515 RDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSS 3574
             DIASD+ Y+  + K+ G  IG ++++DDP++     + ++QS+ +Y++     + +F  
Sbjct: 1300 GDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHL 1359

Query: 3575 PVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWL 3634
            P+DM+ +V AK  Q L SD DY+   H++T LP+   +  A+KA+ LQS+  YKSDL  +
Sbjct: 1360 PMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGM 1419

Query: 3635 RGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHL 3694
            +GIGW+ + S ++E  K+AGE++S+ KYR+  D +KFT + D+P++V AKN+ +  ++ +
Sbjct: 1420 KGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERM 1479

Query: 3695 YTEAWDADKTSIH---VMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISI 3751
            Y      D  S+H   ++PD PD   A+ N+ ++S K+Y   W++++   YD R DAI  
Sbjct: 1480 YR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPF 1536

Query: 3752 KSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKW 3811
            ++A+ASR+IASD++YKEA+ + +G  IG +S++DDP++   ++ G++QS+ EYKK+F K 
Sbjct: 1537 QTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKS 1596

Query: 3812 KTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYK 3871
            +++F S  D   +L AK+ Q L +D+ YR  L + TC P+Q  +  A+KA+ LQSD  YK
Sbjct: 1597 RSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYK 1656

Query: 3872 ADLEWLRGIGWMPQGSPEVLRVKNAQNI 3899
            +DL   RG+GW P GS +V   + A  +
Sbjct: 1657 SDLNLTRGVGWTPPGSYKVEMARRAAEL 1684



 Score =  979 bits (2531), Expect = 0.0
 Identities = 582/1622 (35%), Positives = 924/1622 (56%), Gaps = 63/1622 (3%)

Query: 2537 KAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKW 2596
            + A   + +A+E  Y  G+ +      GA     DP+++  +   K   + EY +D+E+ 
Sbjct: 109  EGAPNRQPLANERAYWTGYGEGNAWCPGAL---PDPEIVRMVEARKSLGE-EYTEDYEQP 164

Query: 2597 KTKFSSPVDMLGVVL-AKKCQTLVSDVDYKN----YLHQWTCLPDQSDVIHARQAYDLQS 2651
            + K S P  +      AKK   L S V+YK      + +++ + D  +++ ++    LQS
Sbjct: 165  RGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQS 224

Query: 2652 DNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLA 2711
            D  Y  D +  +G G                                F +++     +  
Sbjct: 225  DVRYTEDYEQQRGKG-------------------------------SFPAMITPAYQIAK 253

Query: 2712 KNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYD 2771
            + N +  + R Y + + K+   +       E +L ++    Y +  Y    EE + KG  
Sbjct: 254  RANELASDVR-YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQG-YPEEYEEHRGKGSF 311

Query: 2772 MRVDAIPIKAAKASRDIASEFKYKEGYRKQLGH-HIGARAIRDDPKMMWSMHVAKIQSDR 2830
              +     + AK + ++AS+ KY++ + K  G  H  +   +D+  +  +  V K+ S+ 
Sbjct: 312  PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371

Query: 2831 EYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYK-NYLH----QWTCLPDQSDVIH 2885
            EYKKD E  +    +  +        K     SD  YK NY +    ++  +      +H
Sbjct: 372  EYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLH 431

Query: 2886 ARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEI--LSDKIYRQPPDRFKFT 2943
            A +   L S+  YK+D  +   I   +  +      + A ++  L D  YRQ  D+ K++
Sbjct: 432  AMKVGSLASNVAYKAD--YKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 489

Query: 2944 SVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKL 3003
            SVTD+ + V AK NA  ++   Y   ++K+K    +  D P+++ A+ N   +SE  YK 
Sbjct: 490  SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 549

Query: 3004 ANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWS 3063
              E+ K KG++++ DA+ ++AAKAS ++ S+ KYK+ Y K  G  +G      D +++ S
Sbjct: 550  GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 605

Query: 3064 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQ 3123
            + +AK+ S+ EYKK FE+ KT+F  P+DM+ +  AKK QTL SD+DY+  LHE+T LP+ 
Sbjct: 606  LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 665

Query: 3124 NDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPPDKL 3183
                 A++AY LQS+  YK+DL W++G+GW+  GS+++ + K+A +++S+  YRQ  D+L
Sbjct: 666  MKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725

Query: 3184 KFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESL 3243
            KFTSVTDS +   AK +    +   Y    ++   Q  I  D P  + AR N  N SE L
Sbjct: 726  KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785

Query: 3244 YRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKI 3303
            Y+ + E  K +G++LR D++  +AAKA RD+AS+ KYKE Y +  G  IGA+ V  D ++
Sbjct: 786  YKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQM 845

Query: 3304 MWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICL 3363
              SL ++K+QS+ EYKK FE  K++    +DM+ +V A+K Q L +DV YK   H +  L
Sbjct: 846  SHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905

Query: 3364 PDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRP 3423
            P    +  A+KAY LQSDN Y++D++WMKG+GWV   SL V +AK+AGEL+S+  YRQ P
Sbjct: 906  PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 965

Query: 3424 ETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYS 3483
            + LKFTSI DTPE V A+ +      RLY E  +N K       D PE++LAKLN +N S
Sbjct: 966  DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 1025

Query: 3484 DKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDD 3543
            +  YK +  + +  GY LRLDA+P QAAKAS +I SDYKYKE + K  G  +G+R+++DD
Sbjct: 1026 ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1085

Query: 3544 PKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEW 3603
              +  S++   +QSD  YKK FE  K +F  P+DM  +V AKK Q L S+ DYKHPL ++
Sbjct: 1086 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1145

Query: 3604 TCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYR 3663
            T L +   +  A+KA+ LQS+ +Y+SDL ++RG+  V  G++E+E  K+A E++S+ KYR
Sbjct: 1146 TSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYR 1205

Query: 3664 QPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSA 3723
            Q     K+T +TDTP ++ AK +    ++ LY  A +  +    +    P+ + AK+N+A
Sbjct: 1206 QHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAA 1265

Query: 3724 NISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSI 3783
            N+S   Y + W   + + Y L  +A+  ++A+AS DIASD+ Y+  + K++G  IG QS+
Sbjct: 1266 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSV 1325

Query: 3784 EDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYL 3843
             DDP+I      G++QSE +Y++     + +F  P+DM+ ++ AK  Q L +D DYR   
Sbjct: 1326 RDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQY 1385

Query: 3844 HEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDS 3903
            H++T +P+   +  AKKA+ LQS+  YK+DL  ++GIGW+   SP++   K A  +  ++
Sbjct: 1386 HKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISET 1445

Query: 3904 VYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIH---IMPDTPEINL 3960
             YR    ++K+T++VD+P++V AK++  + +   YR     D  S+H   ++PD P+   
Sbjct: 1446 KYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTR 1502

Query: 3961 ARANALNVSNKLYREGWDEMKAGC-DVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHY 4019
            AR NAL++S+K+YR  W++ +AG  D RLDAIP Q A+ASREIASD++YK    + +G  
Sbjct: 1503 ARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQ 1562

Query: 4020 VGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDM 4079
            +G  +  DD +++  L   +LQ++ EY+ D+AK +++  S  D   +L +K SQ L SD+
Sbjct: 1563 IGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDV 1622

Query: 4080 DYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAA 4139
             YR  L Q TC P+Q  +  A+KA++LQSD  YK+DL   RG+GW P  S  V  A+ AA
Sbjct: 1623 HYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAA 1682

Query: 4140 DI 4141
            ++
Sbjct: 1683 EL 1684



 Score =  794 bits (2051), Expect = 0.0
 Identities = 480/1477 (32%), Positives = 792/1477 (53%), Gaps = 62/1477 (4%)

Query: 39   TSDYEQS--ETSKPALAQPA--LAQPASAKPVERRKVIRKKVDPSKFMTPYIAH----SQ 90
            T DYEQ   + S PA+  PA  +A+ A+    + R   + + +      P I      ++
Sbjct: 229  TEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTR 288

Query: 91   KMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHV 150
            +  D +    Y E++E+ +G+       TP  +  KK  +  S++KYR D +  K   H 
Sbjct: 289  ECADQYGQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHY 347

Query: 151  DE-KAKD---IEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKL 206
                A+D   ++ A+ V++ VS+V YK++ E ++   +   + P+     K +   S   
Sbjct: 348  HSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNK 407

Query: 207  YTEDWEADKSLFYPYNDSPELRRVAQAQKA---LSDVAYKKGLAEQQAQFT-PLADPPDI 262
            Y E+++    +   Y      RR   A K     S+VAYK         +  P    P  
Sbjct: 408  YKENYQ--NHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSY 465

Query: 263  EFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQ 322
            + A K+   +    Y++  +       ++TP  ++  A++NA  +S   Y+ D+E  K  
Sbjct: 466  QTAMKLV-PLKDANYRQSIDKLKYSSVTDTP--QIVQAKINAQQLSHVNYRADYEKNKLN 522

Query: 323  IYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDAL 382
             Y +  + P+    K      S+VKYKE +EK KGK     L A     L   KA+G+  
Sbjct: 523  -YTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAM---SLLAAKASGELA 578

Query: 383  SDKLYKENYEKTKAKSINYCET-------------------------PKFKLDTVLQNFS 417
            S+  YKE YEKTK K++   ++                          +F L   + N  
Sbjct: 579  SNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIR 638

Query: 418  SDKKYK----DSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQ 473
              KK +    D   +  L  Y    ED       K     S+  YKA+    +G G+  +
Sbjct: 639  HAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTE 698

Query: 474  TITQEYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESE 533
                  +A K      +  Y+   D+ KFT VTDS  +  A+ + +  S + YKA +E  
Sbjct: 699  GSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQS 758

Query: 534  KFKCHIPPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS 593
              +  I  D P F+Q + NA NLS+ LYK  WE  KAK F++++D++  LAAKA     S
Sbjct: 759  VHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLAS 818

Query: 594  DVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETP 653
            +V YK+DYE+++GK+IG   +  D +M HSL+++K QS+  YK+ +E TK++    C   
Sbjct: 819  EVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQ----CHVS 874

Query: 654  KYQLDTQLKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDK 713
               +       ++    D+  K    H+     D       K     SD  Y+A+ +  K
Sbjct: 875  LDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMK 934

Query: 714  GKCYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNY 773
            G  +         +A K  +   +  Y+ HPD  KFT++ D+P ++QA+++  Q  D  Y
Sbjct: 935  GMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLY 994

Query: 774  KAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAK 833
            + + E  K      AD P+ +  ++NA N+S+  YK+ W K +   + +++DA+P  AAK
Sbjct: 995  REQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAK 1054

Query: 834  ANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIY 893
            A+ +  SD  YK+ +EK KG+M+G+ S+ DD  + HS+     QSD  Y+K +E SK  +
Sbjct: 1055 ASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQF 1114

Query: 894  TAPLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYN 953
              PLDM  +  AKK+Q +AS+ DYKH L  Y+   + + +  AKKA+ LQS+  Y++D N
Sbjct: 1115 HLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN 1174

Query: 954  SWMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRS 1013
             +M+G   V  G+LE+E  K+AS++++E KYRQHP + K+T++ D P  + +K +    +
Sbjct: 1175 -FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITN 1233

Query: 1014 DIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPI 1073
            +  YKA GE+  H+Y +   LP+FI+AK NA N+S+  YK   ++L  +GY L  +A+P 
Sbjct: 1234 ERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPF 1293

Query: 1074 RAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKT 1133
            +AA+A+   ASD  Y+ D+ K +GK++G QS++DDP++ H   + ++QS+ +Y++    +
Sbjct: 1294 QAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSS 1353

Query: 1134 KSKYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYK 1193
            +++++ P DM ++V AK AQ + S+ +Y+   H +T LP+ + +  +K    +QS+  YK
Sbjct: 1354 QAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYK 1413

Query: 1194 EDYNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNT 1253
             D    MKGIGW+ + S  +E  KKAG+ ++E KYR+ PD++KFT++VDSP +V AK + 
Sbjct: 1414 SDLIG-MKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSY 1472

Query: 1254 KQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGD 1313
               ++ +Y++   +  H+YT+ PD P F +A+ NA ++SD  Y+  W    A   +   D
Sbjct: 1473 MHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLD 1532

Query: 1314 AIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKN 1373
            AIP   A+ASR IASD++YKEA+ + +G  +G+RS+ DDP++ H++NV +LQSD EYKK+
Sbjct: 1533 AIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKD 1592

Query: 1374 YENTKTSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSD 1433
            +  +++ +H+  D   +  AK +Q +A++V+Y+QPL   T  P+ + L H +  +Q+QSD
Sbjct: 1593 FAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSD 1652

Query: 1434 NVYKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNER 1470
              YK + N   +G+GW P GS +VE  ++A +  N R
Sbjct: 1653 VKYKSDLN-LTRGVGWTPPGSYKVEMARRAAELANAR 1688



 Score =  785 bits (2028), Expect = 0.0
 Identities = 504/1535 (32%), Positives = 814/1535 (53%), Gaps = 155/1535 (10%)

Query: 1784 YKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKL 1843
            Y   +E+ + KG        A + A+ +  +AS  +YK+ +++   +   F ++ D P+L
Sbjct: 157  YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISR---FSTVVDTPEL 213

Query: 1844 VHFMQVAKMQSDREYKKGYEKSKTSFHTPVDML-SVVAAKKSQEVATNANYRNVIHTYNM 1902
            +     A++QSD  Y + YE+ +     P  +  +   AK++ E+A++  Y    +   M
Sbjct: 214  LRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQ-YQKEM 272

Query: 1903 LPDAMSFELAKNMMQIQSDNQYKADYADFM---KGIGWLPLGSLEAEKN-KKAMEIISEK 1958
               A     A+ ++  +  +QY   Y +     +G G  P     A +N KKA E+ S+ 
Sbjct: 273  RGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDI 332

Query: 1959 KYRQHPDTLK----YSTLMDSMNMVL--AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQ 2012
            KYRQ  + +K    Y +L    N+VL  AQ+  K+++E  YK+  E+ +       + PQ
Sbjct: 333  KYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQ 392

Query: 2013 IILAKANAINMSDKLYKLSLEESKKKGYD----LRPDAIPIKAAKASRDIA--SDYK--- 2063
                   +   SD  YK + +   +  Y+     R     +K    + ++A  +DYK   
Sbjct: 393  FRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDI 452

Query: 2064 --YKY--------------------NYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDRE 2101
              Y Y                    NY +   K+  + S+ D P++V +   A+  S   
Sbjct: 453  VDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKL-KYSSVTDTPQIVQAKINAQQLSHVN 511

Query: 2102 YKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHK-----YILLPDAMNIELT 2156
            Y+ +YE  K +Y  P D+  +  AK      +   YK    K     + +  DAM++   
Sbjct: 512  YRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 571

Query: 2157 RNMNRIQSDNEYKQDYN---------------------------EWYKGLGWS------P 2183
            +    + S+ +YK++Y                            E+ KG   S      P
Sbjct: 572  KASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLP 631

Query: 2184 AGSLEVEKAKKATEYASDQKYRQH----------------------PSNFQFKK------ 2215
               + +  AKKA   ASD  YR+                        S  Q+K       
Sbjct: 632  MDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMK 691

Query: 2216 ----LTD-SMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQK 2270
                LT+ S+++  AK+    +++  Y      D+ K   + D+  +  AK++Q L S  
Sbjct: 692  GVGWLTEGSLNLEQAKKAGQLVSEKNYR--QRVDELKFTSVTDSSQMEHAKKSQELQSGV 749

Query: 2271 LYKLGWEEAL-----------------------------------KKGYDLPVDAISVQL 2295
             YK G E+++                                    KG++L +D+++   
Sbjct: 750  AYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLA 809

Query: 2296 AKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKT 2355
            AKA RD+AS+ KYK+ Y +  G  +G + +Q D ++  S+ ++K+QSE EYKK FE  K+
Sbjct: 810  AKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKS 869

Query: 2356 KFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSD 2415
            +    +DM+ +V A+K Q L +DV YK   H +T LP    V  AKK Y LQS+N Y++D
Sbjct: 870  QCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRAD 929

Query: 2416 LEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNR 2475
            ++W++G+GW   GSL  E+ K+A E+ISEKKYRQ PD  KFTSI D  ++V A+ +    
Sbjct: 930  VKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQA 989

Query: 2476 SDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIP 2535
             DRLYRE  +  K       D P+++LAK N +N S+  Y+  + +L+  GY L +DA+P
Sbjct: 990  VDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALP 1049

Query: 2536 IKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEK 2595
             +AAKAS EI S+YKYKE F K  G  +G+R++EDD  +  S++   +QSD  YKK FE 
Sbjct: 1050 FQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEH 1109

Query: 2596 WKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNLY 2655
             K +F  P+DM  +V AKK QTL S+ DYK+ L Q+T L +   +  A++A+ LQS+NLY
Sbjct: 1110 SKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLY 1169

Query: 2656 KSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLAKNNA 2715
            +SDL +++G+  +  G+LE E  K+A++++S+  YRQHP  FK++++ D+  ++ AK + 
Sbjct: 1170 RSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSN 1229

Query: 2716 ITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVD 2775
               N RLY  A +  +    +    PE + AK N  N S+  YK      + +GY + ++
Sbjct: 1230 QITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIE 1289

Query: 2776 AIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKD 2835
            A+P +AA+AS DIAS+F Y+  + K+ G  IG +++RDDP++     + ++QS+ +Y++ 
Sbjct: 1290 ALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRG 1349

Query: 2836 FEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSD 2895
                + +F  P+DM+ +V AK  Q L SD DY+   H++T LP+   +  A++A+ LQS+
Sbjct: 1350 ATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSE 1409

Query: 2896 NMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAK 2955
              YKSDL  M+GIGW+++ S  +E  K+A E++S+  YR+ PD  KFT+V DS + V AK
Sbjct: 1410 LRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAK 1469

Query: 2956 NNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDL 3015
            N+ ++ N+R+Y     +   +  ++PD P+   AR N ++ S+ +Y+ + E+ +   YD 
Sbjct: 1470 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1529

Query: 3016 RSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREY 3075
            R DAIP   A+ASR++ SD++YK+ + +  G  IG R+++DDP+M   ++V ++QSD EY
Sbjct: 1530 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1589

Query: 3076 KKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDL 3135
            KKDF K +++F S  D  G++ AK+ Q L SDV Y+  L + TC P+Q  + HA++A+ L
Sbjct: 1590 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQL 1649

Query: 3136 QSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEI 3170
            QSD  YKSDL   RG+GW P GS  V   +RAAE+
Sbjct: 1650 QSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1684



 Score =  754 bits (1948), Expect = 0.0
 Identities = 482/1553 (31%), Positives = 809/1553 (52%), Gaps = 73/1553 (4%)

Query: 3363 LPDQNDI--IHARKAYDLQSDNLYKSDLEWMKGIGWVP-IDSLEVVRAKRAGELLSDTIY 3419
            LPD   +  + ARK+   +    Y  D E  +G G  P + +    RAK+A +L S   Y
Sbjct: 138  LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193

Query: 3420 RQRPETL--KFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAK 3476
            ++  +    +F+++ DTPE + +K  A   +   YTE ++  + K       TP   +AK
Sbjct: 194  KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAK 253

Query: 3477 -----LNRINYSDKL-----------------------------YKLALEESKKEGYDLR 3502
                  + + Y  +                              Y    EE + +G    
Sbjct: 254  RANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPA 313

Query: 3503 LDAIPIQAAKASRDIASDYKYKEGYRKQLGH-HIGARNIKDDPKMMWSIHVAKIQSDREY 3561
            +     Q AK + ++ASD KY++ + K  G  H  +   +D+  +  +  V K+ S+ EY
Sbjct: 314  MITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEY 373

Query: 3562 KKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYK-----HPLHEWTCLPDQNDVIQAR 3616
            KK+ E  +    +  +        K     SD  YK     H    +  +      + A 
Sbjct: 374  KKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAM 433

Query: 3617 KAYDLQSDAIYKSD-----LEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKF 3671
            K   L S+  YK+D     +++       P     ++ V      L D  YRQ  D+LK+
Sbjct: 434  KVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVP-----LKDANYRQSIDKLKY 488

Query: 3672 TCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYT 3731
            + +TDTP+IV AK NA  +S   Y   ++ +K +  +  D P ++ AK+N+   S+  Y 
Sbjct: 489  SSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYK 548

Query: 3732 KGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMC 3791
            +GW+++K K ++++ DA+S+ +AKAS ++AS+ KYKE YEK KG  +G      D +++ 
Sbjct: 549  EGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLH 604

Query: 3792 AIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPD 3851
            ++   K+ SE EYKK F++ KT+F  P+DM++I  AKK QTL +D+DYR  LHE+T +P+
Sbjct: 605  SLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPE 664

Query: 3852 QNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDSVYRTPVVN 3911
                  AKKAY LQS+  YKADL W++G+GW+ +GS  + + K A  +  +  YR  V  
Sbjct: 665  DMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDE 724

Query: 3912 LKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINLARANALNVSNK 3971
            LK+TS+ D+ ++  AK + E  S   Y+   ++      I  D P    ARANA N+S K
Sbjct: 725  LKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEK 784

Query: 3972 LYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDNK 4030
            LY+  W+  KA G ++RLD++   AAKA R++AS+ KYK D+E+ +G  +G    + D++
Sbjct: 785  LYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQ 844

Query: 4031 IRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYLHQWTC 4090
            +  +L   KLQ+E EY+  +   K++    +DM+ ++H++ +Q L +D+ Y+   H +T 
Sbjct: 845  MSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTA 904

Query: 4091 MPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTK 4150
            +P    V  AKKAY LQSDN Y+AD++W++G+GW+   S++V  AK A ++ SEKKYR  
Sbjct: 905  LPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQH 964

Query: 4151 IETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLT-ETPLLHTAQEAARIL 4209
             + L FT + D  + V A+ S     D  YR+     K  YT T + P +  A+  A  +
Sbjct: 965  PDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNI 1024

Query: 4210 DQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRD 4269
             +  YKE W + +  GY L  DA+PF  A    ++ S+ KYK    K KG  +G  ++ D
Sbjct: 1025 SETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLED 1084

Query: 4270 DPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNYLHQ 4329
            D  L    +A  +Q++  YK+ +  +KA+ ++P DM +++ AK+ QTL S+ DY++ L Q
Sbjct: 1085 DISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQ 1144

Query: 4330 WMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKNQEMMSQIKY 4389
            +    +   +  A+KA+ LQS+N+YR+DL ++RG+  +   +++     K  E++S+ KY
Sbjct: 1145 YTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKY 1204

Query: 4390 KKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKD 4449
            +++   +   + +V D P ++ AK ++   ++  YK     A+ +YT +   P    +K 
Sbjct: 1205 RQH--PHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKT 1262

Query: 4450 MGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAG 4509
                 S   YK +W   +A GY L    +P   A+ +  + S+  Y+  + K++G  +  
Sbjct: 1263 NAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGP 1322

Query: 4510 KVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYR 4569
            + + + P + HC    +++S L YR+    ++A  H+P DM++ V AK  Q + SD +YR
Sbjct: 1323 QSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYR 1382

Query: 4570 HYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQ 4629
              +H++T+L E+  +   + A  + S+  YK DL  +KGIG     +PQ+  AKK+ +L 
Sbjct: 1383 TQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELI 1442

Query: 4630 SQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDY 4689
            S+ +Y    K +   +  V D+P  V A  S ++ +E  Y+    +   +YT + +  D+
Sbjct: 1443 SETKYRK--KPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1500

Query: 4690 DRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKA 4749
             R R      S  +Y+ +W++ +A SY      +    A+  + +AS  +Y+E + + + 
Sbjct: 1501 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1560

Query: 4750 LYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVS 4809
            L    RSVDDDP     L VG+L  D  Y+  + K++ + H   D   ++ AK SQ+  S
Sbjct: 1561 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1620

Query: 4810 EIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTP 4862
            ++ YR  L +  C P+     H +K     SD+ YK DLN  +G+G   W  P
Sbjct: 1621 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVG---WTPP 1670



 Score =  641 bits (1654), Expect = 0.0
 Identities = 469/1628 (28%), Positives = 772/1628 (47%), Gaps = 210/1628 (12%)

Query: 3057 DPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQTLVSDVDYKN--- 3112
            DP+++  +   K   + EY +D+E+ + K S P  +      AKK   L S V+YK    
Sbjct: 140  DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198

Query: 3113 -YLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVK-CKRAAEI 3170
              +  ++ + D  +++ ++    LQSD  Y  D +  RG G  P       +  KRA E+
Sbjct: 199  ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANEL 258

Query: 3171 LSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIM 3230
             SD  Y Q                                  + K+   +       E +
Sbjct: 259  ASDVRYHQQ---------------------------------YQKEMRGMAGPAIGAEGI 285

Query: 3231 LARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGH 3290
            L R+    Y +  Y +  EE + +G            AK + ++ASD KY++ + K  G 
Sbjct: 286  LTRECADQYGQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGA 344

Query: 3291 -HIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVS 3349
             H  +    D+  +  +  + K+ S+ EYKKD E  +    +  +        K     S
Sbjct: 345  AHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTS 404

Query: 3350 DVDYK-----HPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEV 3404
            D  YK     H    +  +      +HA K   L S+  YK+D +        P      
Sbjct: 405  DNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPS 464

Query: 3405 VRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIH 3464
             +       L D  YRQ  + LK++S+TDTP+ V AK NA  ++   Y   ++ +K    
Sbjct: 465  YQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYT 524

Query: 3465 VMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYK 3524
            +  D P+++ AK N   +S+  YK   E++K +G++++LDA+ + AAKAS ++AS+ KYK
Sbjct: 525  LPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 584

Query: 3525 EGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLA 3584
            E Y K  G  +G      D +++ S+ +AK+ S+ EYKK FE+ KT+F  P+DM+ +  A
Sbjct: 585  EEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHA 640

Query: 3585 KKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGS 3644
            KK Q L SD+DY+  LHE+T LP+      A+KAY LQS+  YK+DL W++G+GW+  GS
Sbjct: 641  KKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGS 700

Query: 3645 VEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKT 3704
            + +E+ K+AG+++S++ YRQ  D+LKFT +TD+ ++  AK +    S   Y    +    
Sbjct: 701  LNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVH 760

Query: 3705 SIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDY 3764
               +  D P  L A++N+AN+S+KLY   W+  K K ++LR D+++  +AKA RD+AS+ 
Sbjct: 761  QYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEV 820

Query: 3765 KYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSI 3824
            KYKE YE+ +G  IGA+ ++ D ++  ++   K+QSE EYKK F+  K++    +DM+ +
Sbjct: 821  KYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHL 880

Query: 3825 LLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMP 3884
            + A+K Q L TD+ Y+   H +T +P    +  AKKAY LQSD  Y+AD++W++G+GW+ 
Sbjct: 881  VHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 940

Query: 3885 QGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDK 3944
             GS  V + K A  +  +  YR     LK+TSI DTPE+V A+ +        YRE  + 
Sbjct: 941  TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGEN 1000

Query: 3945 DKTSIHIMPDTPEINLARANALNVSNKLYREGWDEMK-AGCDVRLDAIPIQAAKASREIA 4003
             K       D PE+ LA+ NA+N+S   Y+E W +++  G  +RLDA+P QAAKAS EI 
Sbjct: 1001 IKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEII 1060

Query: 4004 SDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDM 4063
            SDYKYK   EK KG  +G+ +  DD  +  ++ A  LQ++  Y+  +   KA+   P+DM
Sbjct: 1061 SDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDM 1120

Query: 4064 LSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIG 4123
             +++H+K +Q L S+ DY++ L Q+T + +   +  AKKA++LQS+N+Y++DL ++RG+ 
Sbjct: 1121 AALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVA 1180

Query: 4124 WM---------------------------------PNDSVSVNHAKHAADIFSEKKYRTK 4150
             +                                   D+ ++ HAK +  I +E+ Y+  
Sbjct: 1181 CVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAA 1240

Query: 4151 IETLN--FTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSK-YTLTETPL-LHTAQEAA 4206
             E     +T      +++ AK +   L D +Y++ W   +++ Y LT   L    A+ + 
Sbjct: 1241 GEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASG 1300

Query: 4207 RILDQYLYKEGW--ERQKATG-----------------------------------YILP 4229
             I   +LY+  +  ER K  G                                   + LP
Sbjct: 1301 DIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLP 1360

Query: 4230 PDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYK 4289
             D V  VHA +   + S+  Y+ ++ K    +  +P   +D K+ W + A  +Q+E  YK
Sbjct: 1361 MDMVHLVHAKNAQALASDHDYRTQYHK----FTALP---EDLKMAWAKKAHALQSELRYK 1413

Query: 4290 EDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNY----------------------- 4326
             D    K    +      + +AK+   L+S+  YR                         
Sbjct: 1414 SDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYM 1473

Query: 4327 --------------LHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGW-IPLDS 4371
                          LH++   PD  D  +AR      SD VYR   E  R   +   LD+
Sbjct: 1474 HCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDA 1533

Query: 4372 VDHVRVTKNQEMMSQIKYKKNALENYP---NFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428
            +       ++E+ S  +YK+  L +      +RSV D P +         QSD +YK+ F
Sbjct: 1534 IPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDF 1593

Query: 4429 NKAKGKYTFSPDTPHI-------------------------------SHSKDMGKLYSTI 4457
             K++ ++  S D P +                                H++   +L S +
Sbjct: 1594 AKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDV 1653

Query: 4458 LYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNS-----ELKYKETYEKQKGHYLAGKVI 4512
             YK     T+  G+T    Y   +  + A+L N+     +  Y+     + G + +G+V 
Sbjct: 1654 KYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQSGEVN 1713

Query: 4513 GEFPGVVH 4520
             +   ++H
Sbjct: 1714 PDATEILH 1721



 Score =  626 bits (1614), Expect = e-178
 Identities = 454/1550 (29%), Positives = 754/1550 (48%), Gaps = 124/1550 (8%)

Query: 3647 VEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSI 3706
            VE  K  GE  ++  Y QP  +  F  +  TP    AK      S+  Y    D   +  
Sbjct: 147  VEARKSLGEEYTE-DYEQPRGKGSFPAMI-TPAYQRAKKANQLASQVEYKRGHDERISRF 204

Query: 3707 HVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKY 3766
              + DTP++L +K+ +   S   YT+ +++ + K         + + AK + ++ASD +Y
Sbjct: 205  STVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRY 264

Query: 3767 KEAYEKQ----KGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDML 3822
             + Y+K+     G  IGA+ I       CA   G     + Y +E+++ + K S P  + 
Sbjct: 265  HQQYQKEMRGMAGPAIGAEGILTRE---CADQYG-----QGYPEEYEEHRGKGSFPAMIT 316

Query: 3823 -SILLAKKCQTLVTDIDYRNYLHE------WTCMPDQNDII--QAKKAYDLQSDALYKAD 3873
             +   AKK   L +DI YR   ++      +  +P Q++++  QA+    L S+  YK D
Sbjct: 317  PAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKD 376

Query: 3874 LEWLRGIGWMPQGSPEVLRVKN-------------------------------------- 3895
            LE  RG       +P+   V                                        
Sbjct: 377  LESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVG 436

Query: 3896 --AQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMP 3953
              A N+   + Y+  +V+  Y + + TP    A      +    YR+  DK K S   + 
Sbjct: 437  SLASNVAYKADYKHDIVDYNYPATL-TPSYQTAMKLVP-LKDANYRQSIDKLKYS--SVT 492

Query: 3954 DTPEINLARANALNVS----------NKL-------------------------YREGWD 3978
            DTP+I  A+ NA  +S          NKL                         Y+EGW+
Sbjct: 493  DTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWE 552

Query: 3979 EMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIA 4037
            + K  G +++LDA+ + AAKAS E+AS+ KYK ++EK KG  +GT     D+++  +L  
Sbjct: 553  KTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQI 608

Query: 4038 DKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDV 4097
             K+ +E EY+  + + K +   P+DM++I H+K +Q L SD+DYR  LH++T +P+    
Sbjct: 609  AKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKT 668

Query: 4098 IQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFT 4157
              AKKAY LQS+  YKADL W++G+GW+   S+++  AK A  + SEK YR +++ L FT
Sbjct: 669  QWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFT 728

Query: 4158 PVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLT-ETPLLHTAQEAARILDQYLYKE 4216
             V D      AK+S E+   + Y+     +  +YT++ + PL   A+  A  L + LYK 
Sbjct: 729  SVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKS 788

Query: 4217 GWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWF 4276
             WE QKA G+ L  D++ F+ A    D+ SE+KYK ++ + +G  +G   ++ D ++   
Sbjct: 789  SWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHS 848

Query: 4277 EHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQ 4336
                ++Q+E  YK+ +  TK++ ++  DMV ++ A++ Q L +D+ Y+   H +   P  
Sbjct: 849  LQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTD 908

Query: 4337 NDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKNQEMMSQIKYKKNALEN 4396
              V  A+KAY LQSDN YRAD++W++G+GW+   S++  +  K  E++S+ KY+++   +
Sbjct: 909  MKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQH--PD 966

Query: 4397 YPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYST 4456
               F S+ D PE+V A+I+     D  Y+E     K  YT + D P +  +K      S 
Sbjct: 967  ALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISE 1026

Query: 4457 ILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFP 4516
              YK +W   +  GY L    +P   AK +  + S+ KYKE +EK KG  L  + + +  
Sbjct: 1027 TRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDI 1086

Query: 4517 GVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWT 4576
             + H +    ++S +NY+K +E +KA  H+P DM   V AK+ Q + S+ +Y+H   Q+T
Sbjct: 1087 SLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYT 1146

Query: 4577 SLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTA 4636
            SL E+  +   + A ++ S+N+Y+ DLN+++G+ C +  T +I   KK+ +L S+ +Y  
Sbjct: 1147 SLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ 1206

Query: 4637 AGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLK 4696
                +   Y  VTDTP  + A  S    +E  YK      + +YT  L   ++ R +   
Sbjct: 1207 --HPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNA 1264

Query: 4697 NLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRS 4756
               S   YKE+W  ++A  Y L    L    A+    +AS   YR ++ K +     P+S
Sbjct: 1265 ANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQS 1324

Query: 4757 VDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLR 4816
            V DDP    C R+G+L  +  YR     ++ + H+  DMV +V AK++Q   S+ DYR +
Sbjct: 1325 VRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQ 1384

Query: 4817 LHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDD 4876
             H++   P+       +K     S++ YK DL  +KGIG     +P++  AK A +L  +
Sbjct: 1385 YHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISE 1444

Query: 4877 IKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLD 4936
             KY+      +  +  V D+P  V A  S    ++ +Y      S+  +        D  
Sbjct: 1445 TKYRKKPDSIK--FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLH-RYTLIPDHPDFT 1501

Query: 4937 RA-LHAYKLQSSNLYKTSLRTLPTG-YRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKA 4994
            RA L+A  L S  +Y+ S      G Y    D   F+  + +R ++S F+YKEA+   + 
Sbjct: 1502 RARLNALHL-SDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1560

Query: 4995 --YGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVS 5052
               GY     D    H   V  + S+  Y++ + K + + H++ D P + Q K++Q+  S
Sbjct: 1561 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1620

Query: 5053 ELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFG 5102
            ++ Y+             P    + H +    + SD+KYK DL + +G G
Sbjct: 1621 DVHYRQPL----PQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVG 1666



 Score =  438 bits (1127), Expect = e-122
 Identities = 404/1585 (25%), Positives = 701/1585 (44%), Gaps = 114/1585 (7%)

Query: 4045 EYRLDWAKWKAKIQSPVDML-SILHSKNSQALVSDMDYRN----YLHQWTCMPDQNDVIQ 4099
            EY  D+ + + K   P  +  +   +K +  L S ++Y+      + +++ + D  ++++
Sbjct: 156  EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLR 215

Query: 4100 AKKAYELQSDNVYKADLEWLRGIGWMPND-SVSVNHAKHAADIFSEKKYRTKIETLN--- 4155
            +K   +LQSD  Y  D E  RG G  P   + +   AK A ++ S+ +Y  + +      
Sbjct: 216  SKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGM 275

Query: 4156 FTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLHTAQEAARILDQYLYK 4215
              P       +T + + +         + +  K  +    TP    A++A  +     Y+
Sbjct: 276  AGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYR 335

Query: 4216 EGWERQKATGYI--LPP-DAVPFVHAHHCNDVQSELKYKAEHVKQKGH---YVGVPTMRD 4269
            + + + K   +   LP  D +    A   N + SE++YK +    +GH   Y   P  R+
Sbjct: 336  QDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRN 395

Query: 4270 DPKLVWFEHAGQIQNERLYKEDY--HKTKAKINIPADMVSVLAAKQGQTLVSDIDYR-NY 4326
              K+  F       ++  YKE+Y  H       +  D  ++ A K G +L S++ Y+ +Y
Sbjct: 396  VSKISKFT------SDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVG-SLASNVAYKADY 448

Query: 4327 LHQWMCHPDQNDVIQARKAYDLQSDNVYRADL--EWLRGIGWIPLDSVDHVRVTKNQEMM 4384
             H         D++          D  Y A L   +   +  +PL   ++      ++ +
Sbjct: 449  KH---------DIV----------DYNYPATLTPSYQTAMKLVPLKDANY------RQSI 483

Query: 4385 SQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHI 4444
             ++KY            SV D P+IV AKIN+   S V Y+  + K K  YT   D P +
Sbjct: 484  DKLKYS-----------SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQL 532

Query: 4445 SHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKG 4504
              +K   KL+S + YK  WE TK  G+ +    + ++ AK +  + S +KYKE YEK KG
Sbjct: 533  VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 592

Query: 4505 HYLAGKVIGEFPG-VVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYIL 4563
                 K +G     ++H L   KM S + Y+K +E++K   H+P DM+N   AK+ Q + 
Sbjct: 593  -----KAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 647

Query: 4564 SDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAK 4623
            SDL+YR   H++T L E+      + A  + S+  YK DL W+KG+G     +  +  AK
Sbjct: 648  SDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAK 707

Query: 4624 KSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTV 4683
            K+  L S+  Y     E    +  VTD+     A +S    S V YK    Q   +YT  
Sbjct: 708  KAGQLVSEKNYRQRVDE--LKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTIS 765

Query: 4684 LETVDYDRTR-NLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYRE 4742
             +   + + R N  NL S  LYK +W+  KA  + L   +L+   AK ++ LAS +KY+E
Sbjct: 766  KDEPLFLQARANAANL-SEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKE 824

Query: 4743 EYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAK 4802
            +YE+ +      + V  D   +  L++ KL  +  Y+  +E  K + H+  DMV +V A+
Sbjct: 825  DYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHAR 884

Query: 4803 DSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTP 4862
             +Q   +++ Y+   H +   P     +  +K     SD  Y+ D+ W+KG+G     + 
Sbjct: 885  KAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSL 944

Query: 4863 EILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSV 4922
             +  AK A +L  + KY+ H    +  +  + DTP  VQA  S  Q  D +Y  +   ++
Sbjct: 945  NVEQAKKAGELISEKKYRQHPDALK--FTSIKDTPEMVQARISYTQAVDRLYR-EQGENI 1001

Query: 4923 RGKVAPTTKTVDLDRALHAYKLQSSNL----YKTSLRTL-PTGYRLPGDTPHFKHIKDTR 4977
            +    P   T DL   L A KL + N+    YK S   L   GY+L  D   F+  K + 
Sbjct: 1002 KHHYTP---TADLPEVLLA-KLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASG 1057

Query: 4978 YMSSYFKYKEAYEHTKAYGYTLGPK----DVPFVHVRRVNNVTSERLYRELYHKLKDKIH 5033
             + S +KYKEA+E  K  G  LG +    D+   H     ++ S+  Y++ +   K + H
Sbjct: 1058 EIISDYKYKEAFEKMK--GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1115

Query: 5034 TTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKE 5093
               D   +   KK Q   S   YK           SL    ++   +    + S+  Y+ 
Sbjct: 1116 LPLDMAALVHAKKAQTLASNQDYKHPL----PQYTSLAEDLRLSCAKKAHKLQSENLYRS 1171

Query: 5094 DLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELK 5153
            DL  ++G  C +  T ++   +   +L S   Y         KY  V DTP     +   
Sbjct: 1172 DLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSF--KYTAVTDTPNLLHAKFSN 1229

Query: 5154 THLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQ 5212
               +E +Y+AAG+  +  +T     P+ +RAK      S   Y E     R   +    +
Sbjct: 1230 QITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIE 1289

Query: 5213 TTALKHAKDVKDMVSEKKYKIQYEKMKDKY---TPVPDTPILIRAKRAYWNASDLRYKET 5269
                + A+   D+ S+  Y+  + K + K      V D P +   +R     S+L+Y+  
Sbjct: 1290 ALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRG 1349

Query: 5270 FQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTD 5329
               ++ ++H   D + +V+ +    +   +    +Y +Q   + ++P+  +    +    
Sbjct: 1350 ATSSQAQFHLPMDMVHLVHAK----NAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHA 1405

Query: 5330 TVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSP 5389
              S+++YK DL  +KGIG  A  +P    A+K   L S+ KY++  +  K  F  V DSP
Sbjct: 1406 LQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIK--FTTVVDSP 1463

Query: 5390 INRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSK 5449
               H K +    NE+ YR+   +   +Y L+ D P    A+     +S   YR ++E+++
Sbjct: 1464 DLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTR 1523

Query: 5450 DKFTSIVDTPEHLRTTKVNKQI-SDILYKLEY--NKAKPRGYTTIHDTPMLLHVRKVKDE 5506
                         +T + +++I SD  YK  +  ++    GY ++ D P + H   V   
Sbjct: 1524 AGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRL 1583

Query: 5507 VSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPD 5566
             SD +YK+ + +++S      D   +  AK + ++ +++ Y++            P++  
Sbjct: 1584 QSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTC----DPEQLG 1639

Query: 5567 FLQAAKSSLQQSDFEYKLDREFLKG 5591
               A K+   QSD +YK D    +G
Sbjct: 1640 LRHAQKAHQLQSDVKYKSDLNLTRG 1664



 Score =  409 bits (1051), Expect = e-113
 Identities = 404/1636 (24%), Positives = 714/1636 (43%), Gaps = 200/1636 (12%)

Query: 4334 PDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIP-LDSVDHVRVTKNQEMMSQIKYKKN 4392
            P+   +++ARK+   +    Y  D E  RG G  P + +  + R  K  ++ SQ++YK+ 
Sbjct: 141  PEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196

Query: 4393 ALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTF-SPDTPHISHSKDMG 4451
              E    F +VVD PE++ +K  +  QSDV+Y E + + +GK +F +  TP    +K   
Sbjct: 197  HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRAN 256

Query: 4452 KLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELK------YKETYEKQKGH 4505
            +L S + Y       + Y   +     P +GA+   ++  E        Y E YE+ +G 
Sbjct: 257  ELASDVRYH------QQYQKEMRGMAGPAIGAE--GILTRECADQYGQGYPEEYEEHRGK 308

Query: 4506 YLAGKVIGEFPGVV-----HCLDFQKMRSALNYRKHYEDTKANVHIPN-DMMNHVLAKRC 4559
                   G FP ++     +     ++ S + YR+ +   K   H  +    ++++ K+ 
Sbjct: 309  -------GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQA 361

Query: 4560 QYI---LSDLEYRHYFHQWT----SLLEEPNVIRVRNAQEILSDNVYKDDL-NWLKGIGC 4611
            Q +   +S++EY+           +  E P    V    +  SDN YK++  N ++G   
Sbjct: 362  QSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYE 421

Query: 4612 YVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNL-VTDTPLYVTA------------- 4657
             V    + LHA K   L S + Y A  K ++ +YN   T TP Y TA             
Sbjct: 422  GVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQ 481

Query: 4658 ----------------VQSGINA---SEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNL 4698
                            VQ+ INA   S V Y+ +Y + K  YT   +     + +    L
Sbjct: 482  SIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKL 541

Query: 4699 YSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFK--ALYTLPRS 4756
            +S   YKE W++ K   + +    +SL  AK    LAS+IKY+EEYEK K  A+ T    
Sbjct: 542  FSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA--- 598

Query: 4757 VDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLR 4816
               D      L++ K++ +  Y+  +E++K + H+  DMV +  AK +Q   S++DYR +
Sbjct: 599  ---DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKK 655

Query: 4817 LHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDD 4876
            LHE+   P+       +K     S++ YK DL W+KG+G     +  +  AK A  L  +
Sbjct: 656  LHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSE 715

Query: 4877 IKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLD 4936
              Y+  + + +  +  VTD+     A KS +  S   Y      SV        + + L 
Sbjct: 716  KNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQ 773

Query: 4937 RALHAYKLQSSNLYKTSLRTLPT-GYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAY 4995
               +A  L S  LYK+S       G+ L  D+  F   K  R ++S  KYKE YE ++  
Sbjct: 774  ARANAANL-SEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSR-- 830

Query: 4996 GYTLGPKDVP----FVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAV 5051
            G  +G KDV       H  +++ + SE  Y++ +   K + H + D   +   +K Q   
Sbjct: 831  GKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLA 890

Query: 5052 SELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDM 5111
            +++ YK+     + H  +LP   +V   +    + SD +Y+ D++ +KG G     + ++
Sbjct: 891  TDVGYKT----AEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNV 946

Query: 5112 VRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSI 5171
             +++   +L S   Y      +  K+  + DTPE  + +   T   + +YR  G+  K  
Sbjct: 947  EQAKKAGELISEKKYRQHPDAL--KFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH 1004

Query: 5172 FTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKK 5230
            +T   D P++L AK      S+  Y E  +K R   +         + AK   +++S+ K
Sbjct: 1005 YTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYK 1064

Query: 5231 YKIQYEKMKDKYT---PVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIV 5287
            YK  +EKMK +      + D   L  +  A    SD+ YK+ F+ +K ++H   D   +V
Sbjct: 1065 YKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALV 1124

Query: 5288 YHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG 5347
            + +K     S   YK        +   +        H+  ++ +    Y+ DL +++G+ 
Sbjct: 1125 HAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENL----YRSDLNFMRGVA 1180

Query: 5348 CYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVA--DSPINRHFKYATQLMNEKK 5405
            C    T +    +K   L S+ KY++        FKY A  D+P   H K++ Q+ NE+ 
Sbjct: 1181 CVIPGTLEIEGRKKASELISESKYRQ----HPHSFKYTAVTDTPNLLHAKFSNQITNERL 1236

Query: 5406 YRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTT 5465
            Y+A  E  + +Y + +  P  + AKT    +S  +Y++++   + +   +       +  
Sbjct: 1237 YKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAA 1296

Query: 5466 KVNKQI-SDILYKLEYNKAKPR--GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSN 5522
            + +  I SD LY+ ++ K + +  G  ++ D P + H R++    S+L+Y+     +++ 
Sbjct: 1297 RASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQ 1356

Query: 5523 CTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEY 5582
              +  D VH+  AK+A  + ++ DY+ QY    A     P+      A K+   QS+  Y
Sbjct: 1357 FHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTA----LPEDLKMAWAKKAHALQSELRY 1412

Query: 5583 KLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKT 5642
            K D   +KG             A +   + S+ KY++K    + T   V D+P ++ AK 
Sbjct: 1413 KSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFT--TVVDSPDLVHAKN 1470

Query: 5643 VSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT--------------- 5687
                 +E  Y+    + L +  YT +P+  D    +    H+SD                
Sbjct: 1471 SYMHCNERMYRSGDAESLHR--YTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYD 1528

Query: 5688 ---------------------NYKKKFVKEKG-KSNYSIMLEPPEVKHAMEVAKKQSDVA 5725
                                  YK+ F++++G +  Y  + + P +KH + V + QSD  
Sbjct: 1529 FRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNE 1588

Query: 5726 YRKD-AKENLHYTTVADRPDIKKATQAAKQASEVEYRA--------------KHRKEGSH 5770
            Y+KD AK    + +  D+P + +A ++ + AS+V YR               +H ++   
Sbjct: 1589 YKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQ 1648

Query: 5771 -----------------GLSMLGRPDIEMAKKAAKLSS------QVKYRENFDKEKG--K 5805
                             G +  G   +EMA++AA+L++      Q  YR     E G  +
Sbjct: 1649 LQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQ 1708

Query: 5806 TPKYNPKDSQLYKVMK 5821
            + + NP  +++  V K
Sbjct: 1709 SGEVNPDATEILHVKK 1724



 Score =  348 bits (892), Expect = 1e-94
 Identities = 385/1558 (24%), Positives = 678/1558 (43%), Gaps = 103/1558 (6%)

Query: 4651 TPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDR 4710
            TP Y  A ++   AS+V+YK  + +   +++TV++T +  R++    L S   Y E +++
Sbjct: 175  TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ 234

Query: 4711 VKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVG 4770
             +         T +   AK    LAS ++Y ++Y+K       P    +   T  C    
Sbjct: 235  QRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECAD-- 292

Query: 4771 KLNIDRLYRSVYEKNKMKIHIVPDMVEMV--TAKDSQKKVSEIDYRLRLHEW-------- 4820
                 + Y   YE+++ K    P M+      AK + +  S+I YR   ++         
Sbjct: 293  --QYGQGYPEEYEEHRGK-GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHS 349

Query: 4821 ICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYK 4880
            +   D  V    + V   +S++ YK DL   +G      +TP+  +         D KYK
Sbjct: 350  LPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYK 409

Query: 4881 A-HMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRAL 4939
              +    R  Y+ V      + A+K G   S+  Y  DY H +     P T T     A+
Sbjct: 410  ENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAM 469

Query: 4940 HAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTL 4999
                L+ +N Y+ S+  L   Y    DTP     K      S+  Y+  YE  K   YTL
Sbjct: 470  KLVPLKDAN-YRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTL 525

Query: 5000 GPKDVPFVHVRRVN-NVTSERLYRELYHKLKDK-IHTTPDTPEIRQVKKTQEAVSELIYK 5057
             P+DVP +   + N  + SE  Y+E + K K K      D   +   K + E  S + YK
Sbjct: 526  -PQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 584

Query: 5058 SDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHL 5117
             ++ K +G  +      +++H   +  ++S+++YK+  +  K      +   DMV  RH 
Sbjct: 585  EEYEKTKGKAMGTA-DSRLLHSLQIAKMSSEVEYKKGFEESK---TRFHLPMDMVNIRHA 640

Query: 5118 RKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHL---SELVYRAAGKKQKSIFTS 5174
            +K  +     D  +K+ + Y V+   PE  K Q  K      SEL Y+A     K +   
Sbjct: 641  KKAQTLASDLDYRKKLHE-YTVL---PEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWL 696

Query: 5175 VPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAKDVKDMVSEKKYKIQ 5234
               + +L +AK+  +L S+  Y +   + +    +   ++ ++HAK  +++ S   YK  
Sbjct: 697  TEGSLNLEQAKKAGQLVSEKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAG 754

Query: 5235 YEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVK-DALDIVYHRKVT 5293
             E+   +YT   D P+ ++A+    N S+  YK +++  K K   ++ D+L  +  +   
Sbjct: 755  NEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKR 814

Query: 5294 DDISKIKYKENYMSQLGIW---RSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYA 5350
            D  S++KYKE+Y    G     + +    +  H   ++   S+++YK+     K     +
Sbjct: 815  DLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVS 874

Query: 5351 YDTPDFTLAEKNKTLYSKYKYKEV---FERTKSDFKYVADSPINRHFKYATQLMNEKKYR 5407
             D      A K + L +   YK     F    +D K           K A  L ++ +YR
Sbjct: 875  LDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKV-------EWAKKAYGLQSDNQYR 927

Query: 5408 ADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKV 5467
            AD +  K    +         AK AG+ IS+ KYR++ +    KFTSI DTPE ++    
Sbjct: 928  ADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDAL--KFTSIKDTPEMVQARIS 985

Query: 5468 NKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQR-NKSNCTIE 5526
              Q  D LY+ +    K   YT   D P +L  +     +S+ +YKE + +       + 
Sbjct: 986  YTQAVDRLYREQGENIK-HHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLR 1044

Query: 5527 PDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKS---SLQQSDFEYK 5583
             DA+  +AAK + ++ ++  YK+ +E  K     +    D +  A S   +  QSD  YK
Sbjct: 1045 LDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYK 1104

Query: 5584 LDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTV 5643
               E  K       D    V A +   + S+  Y  KH   + T  ++ +  ++  AK  
Sbjct: 1105 KGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDY--KHPLPQYT--SLAEDLRLSCAKKA 1160

Query: 5644 SNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYS 5703
              L SEN Y+  +  +  +G    +P T +    K+ ++ +S++ Y+    +      Y+
Sbjct: 1161 HKLQSENLYRSDL--NFMRGVACVIPGTLEIEGRKKASELISESKYR----QHPHSFKYT 1214

Query: 5704 IMLEPPEVKHAMEVAKKQSDVAYRKDAKENLH-YTTVADRPDIKKATQAAKQASEVEYRA 5762
             + + P + HA    +  ++  Y+   ++  H YT     P+  +A   A   S+  Y+ 
Sbjct: 1215 AVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKE 1274

Query: 5763 KHRKEGSHGLSM-LGRPDIEMAKKAAKLSSQVKYRENFDKEKGK-TPKYNPKDSQLYKVM 5820
              R   + G  + +     + A+ +  ++S   YR +F KE+GK     + +D    +  
Sbjct: 1275 SWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHC 1334

Query: 5821 KDANNLASEVKYK----ADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKG 5876
            +    L SE++Y+    +   + H P+    + + + H  N   LAS + Y+ +Y K   
Sbjct: 1335 RRMGQLQSELQYRRGATSSQAQFHLPM----DMVHLVHAKNAQALASDHDYRTQYHK--- 1387

Query: 5877 HYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKE 5936
             +  +P++L+    K+A  LQS ++YK      +G   L   +P   +AK++ ++ S  +
Sbjct: 1388 -FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETK 1446

Query: 5937 YRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDM 5996
            YRK   +SIK    T +  +P L+H K +    +E+ YR    ES+     T + D PD 
Sbjct: 1447 YRKK-PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLH--RYTLIPDHPDF 1500

Query: 5997 LRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEME 6056
             RA+     L++K Y+   E + +    +   +  P F  AR + +IAS  +YK++   +
Sbjct: 1501 TRARLNALHLSDKVYRNSWE-QTRAGSYDFRLDAIP-FQTARASREIASDFRYKEAFLRD 1558

Query: 6057 KA---NFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKN 6113
            +     + SV D P + H   V  L S  +YK+D  KS S + +  D P + + + +Q+ 
Sbjct: 1559 RGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQL 1618

Query: 6114 FSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNF---SSVLYKEDVSPGTAIGKTP 6168
             S + Y+  L             PE L ++  QK     S V YK D++    +G TP
Sbjct: 1619 ASDVHYRQPLPQP-------TCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTP 1669



 Score =  338 bits (866), Expect = 1e-91
 Identities = 402/1677 (23%), Positives = 712/1677 (42%), Gaps = 184/1677 (10%)

Query: 3726 SQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIED 3785
            +++ Y  G+ E          D   ++  +A + +  +Y   E YE+ +G   G+     
Sbjct: 119  NERAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYT--EDYEQPRGK--GSFPAMI 174

Query: 3786 DPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHE 3845
             P    A  A ++ S+ EYK+   +  ++FS+ VD   +L +K    L +D+ Y     +
Sbjct: 175  TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ 234

Query: 3846 WTCMPDQNDIIQ-----AKKAYDLQSDALYKADLE-WLRGIGWMPQGSPEVLRVKNAQNI 3899
                     +I      AK+A +L SD  Y    +  +RG+     G+  +L  + A   
Sbjct: 235  QRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294

Query: 3900 --FCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHI--MPDT 3955
                   Y        + +++ TP    AK   E  S  KYR+ ++K K + H   +P  
Sbjct: 295  GQGYPEEYEEHRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353

Query: 3956 PEINLARANALN--VSNKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHE 4013
              + L +A ++N  VS   Y++  +  +       +    +      +  SD KYK +++
Sbjct: 354  DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQ 413

Query: 4014 K-QKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNS 4072
               +G Y G      D +   A+    L +   Y+ D+         P  +     +   
Sbjct: 414  NHMRGRYEG---VGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMK 470

Query: 4073 QALVSDMDYRNYLH--QWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSV 4130
               + D +YR  +   +++ + D   ++QAK   +  S   Y+AD E  +    +P D  
Sbjct: 471  LVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVP 530

Query: 4131 SVNHAKHAADIFSEKKYR---TKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNAT 4187
             +  AK  A +FSE KY+    K +   F    D +  + AK SGE+  +IKY++++  T
Sbjct: 531  QLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKT 590

Query: 4188 KSKYTLT-ETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQS 4246
            K K   T ++ LLH+ Q  A++  +  YK+G+E  K T + LP D V   HA     + S
Sbjct: 591  KGKAMGTADSRLLHSLQ-IAKMSSEVEYKKGFEESK-TRFHLPMDMVNIRHAKKAQTLAS 648

Query: 4247 ELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMV 4306
            +L Y+    K+   Y  +P   +D K  W + A  +Q+E  YK D    K    +    +
Sbjct: 649  DLDYR----KKLHEYTVLP---EDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSL 701

Query: 4307 SVLAAKQGQTLVSDIDYRNYLHQ--WMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGI 4364
            ++  AK+   LVS+ +YR  + +  +    D + +  A+K+ +LQS   Y+A  E     
Sbjct: 702  NLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQ 761

Query: 4365 GWIPLDSVDHVRVTKNQEMMSQIKYKKN-ALENYPNFRSVVDPPEIVLAKINSVNQSDVK 4423
              I  D    ++   N   +S+  YK +   +    F   +D    + AK      S+VK
Sbjct: 762  YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 821

Query: 4424 YKETFNKAKGKYTFSPDT---PHISHSKDMGKLYSTILYKGAWEGTKAYGY-TLDERYIP 4479
            YKE + +++GK   + D      +SHS  M KL S + YK  +E TK+  + +LD   + 
Sbjct: 822  YKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLD--MVH 879

Query: 4480 IVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYED 4539
            +V A+ A  + +++ YK      + H+ A                               
Sbjct: 880  LVHARKAQHLATDVGYKTA----EHHFTA------------------------------- 904

Query: 4540 TKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTS-----LLEEPNVIRVRNAQEIL 4594
                  +P DM     AK+   + SD +YR    +W            NV + + A E++
Sbjct: 905  ------LPTDMKVE-WAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLNVEQAKKAGELI 956

Query: 4595 SDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLY 4654
            S+  Y+   + LK     + DTP+++ A+ SY       Y   G+    +Y    D P  
Sbjct: 957  SEKKYRQHPDALKFTS--IKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEV 1014

Query: 4655 VTAVQSGINASEVKYKENYHQIKD-KYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKA 4713
            + A  + +N SE +YKE++ +++D  Y   L+ + +   +    + S   YKEA++++K 
Sbjct: 1015 LLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK- 1073

Query: 4714 TSYILPSSTL----SLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRV 4769
               +L S +L    SL H+     L S + Y++ +E  KA + LP               
Sbjct: 1074 -GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPL-------------- 1118

Query: 4770 GKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVN 4829
                                    DM  +V AK +Q   S  DY+  L ++    +    
Sbjct: 1119 ------------------------DMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRL 1154

Query: 4830 DHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRND 4889
               +K     S+ +Y+ DLN+++G+ C +  T EI   K A +L  + KY+ H    +  
Sbjct: 1155 SCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK-- 1212

Query: 4890 YKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVA--PTTKTVDLDRALHAYKLQSS 4947
            Y  VTDTP  + A  S +  ++ +Y         G+ A    T T+ L   + A K  ++
Sbjct: 1213 YTAVTDTPNLLHAKFSNQITNERLY------KAAGEDARHEYTMTLGLPEFIRA-KTNAA 1265

Query: 4948 NL----YKTSLRTL-PTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPK 5002
            NL    YK S R L   GY+L  +   F+  + +  ++S F Y+  ++  K  G  +GP+
Sbjct: 1266 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYR--HDFVKERGKLIGPQ 1323

Query: 5003 ----DVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKS 5058
                D    H RR+  + SE  YR      + + H   D   +   K  Q   S+  Y++
Sbjct: 1324 SVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRT 1383

Query: 5059 DFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLR 5118
             + K      +LP   ++   +    + S+++YK DL  +KG G     +P M  ++   
Sbjct: 1384 QYHK----FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAG 1439

Query: 5119 KLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDT 5178
            +L S   Y  K   +  K+  V+D+P+    +    H +E +YR+   +    +T +PD 
Sbjct: 1440 ELISETKYRKKPDSI--KFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDH 1497

Query: 5179 PDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTAL-----KHAKDVKDMVSEKKYK- 5232
            PD  RA    +L + +L  ++         AG+    L     + A+  +++ S+ +YK 
Sbjct: 1498 PDFTRA----RLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKE 1553

Query: 5233 --IQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHR 5290
              ++   ++  Y  V D P +          SD  YK+ F K++ ++H+  D   ++  +
Sbjct: 1554 AFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAK 1613

Query: 5291 KVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG 5347
            +     S + Y++     L      P++    H +      SDVKYK DL   +G+G
Sbjct: 1614 RSQQLASDVHYRQ----PLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVG 1666



 Score =  323 bits (829), Expect = 3e-87
 Identities = 381/1576 (24%), Positives = 656/1576 (41%), Gaps = 122/1576 (7%)

Query: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY-VWDTPQILHAKKSYDLQSQLQYTAA 4637
            L +P ++R+  A++ L +  Y +D    +G G +    TP    AKK+  L SQ++Y   
Sbjct: 138  LPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196

Query: 4638 GKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYT-TVLETVDYDRTRNLK 4696
              E +  ++ V DTP  + +       S+V+Y E+Y Q + K +   + T  Y   +   
Sbjct: 197  HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRAN 256

Query: 4697 NLYSSNLYKEAWD---RVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTL 4753
             L S   Y + +    R  A   I     L+   A           Y EEYE+ +   + 
Sbjct: 257  ELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQ-----GYPEEYEEHRGKGSF 311

Query: 4754 PRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHI----VPDMVEMVTAKDSQKKVS 4809
            P  +   P      +  +L  D  YR  + K K   H       D + +  A+   K VS
Sbjct: 312  PAMI--TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369

Query: 4810 EIDYRLRLHEWICHP----DLQVNDHVRKVTDQISDIVYKDDL-NWLKGIGCYVWDTPEI 4864
            E++Y+  L     H     +     +V K++   SD  YK++  N ++G    V      
Sbjct: 370  EVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRT 429

Query: 4865 LHAKHAYDLRDDIKYKAHM-------------------------LKTRN--------DYK 4891
            LHA     L  ++ YKA                           LK  N         Y 
Sbjct: 430  LHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 489

Query: 4892 LVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYK 4951
             VTDTP  VQA  + +QLS   Y  DY  +      P      L +A    KL S   YK
Sbjct: 490  SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLP-QDVPQLVKAKTNAKLFSEVKYK 548

Query: 4952 TSL-RTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPKDVPFVHVR 5010
                +T   G+ +  D       K +  ++S  KYKE YE TK  G  +G  D   +H  
Sbjct: 549  EGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK--GKAMGTADSRLLHSL 606

Query: 5011 RVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISL 5070
            ++  ++SE  Y++ + + K + H   D   IR  KK Q   S+L Y+    K+  + + L
Sbjct: 607  QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRK---KLHEYTV-L 662

Query: 5071 PYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKA 5130
            P   +    +    + S+++YK DL  +KG G     + ++ +++   +L S   Y  + 
Sbjct: 663  PEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRV 722

Query: 5131 RKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKL 5190
             ++  K+  V D+ +    ++ +   S + Y+A  ++    +T   D P  L+A+     
Sbjct: 723  DEL--KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN 780

Query: 5191 QSQYLYVELATKERPH-HHAGNQTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDT- 5248
             S+ LY      ++         +     AK  +D+ SE KYK  YE+ + K     D  
Sbjct: 781  LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ 840

Query: 5249 --PILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYK--EN 5304
                +  + +     S+L YK+ F+ TK + H   D + +V+ RK     + + YK  E+
Sbjct: 841  GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH 900

Query: 5305 YMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKT 5364
            + +      ++P   +    +      SD +Y+ D+ W+KG+G  A  + +   A+K   
Sbjct: 901  HFT------ALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGE 954

Query: 5365 LYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEP 5424
            L S+ KY++  +  K  F  + D+P     + +     ++ YR   E  K  Y    D P
Sbjct: 955  LISEKKYRQHPDALK--FTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLP 1012

Query: 5425 RHLLAKTAGDQISQIKYRKNYEKSKD-KFTSIVDTPEHLRTTKVNKQISDILYKLEYNKA 5483
              LLAK     IS+ +Y++++ K +D  +   +D           + ISD  YK  + K 
Sbjct: 1013 EVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKM 1072

Query: 5484 KPR--GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKV 5541
            K +  G  ++ D   L H        SD+ YK+ ++ +K+   +  D   +  AK A  +
Sbjct: 1073 KGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTL 1132

Query: 5542 NTNLDYKKQYEANKAHWKWTPDRPDF-LQAAKSSLQ-QSDFEYKLDREFLKGCKLSVTDD 5599
             +N DYK          ++T    D  L  AK + + QS+  Y+ D  F++G    +   
Sbjct: 1133 ASNQDYKHPLP------QYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGT 1186

Query: 5600 KNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKH 5659
                   + + + S+ KY++     + T  AV DTP +L AK  + + +E  YK      
Sbjct: 1187 LEIEGRKKASELISESKYRQHPHSFKYT--AVTDTPNLLHAKFSNQITNERLYK--AAGE 1242

Query: 5660 LAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAK 5719
             A+  YT      + +  K    ++SD  YK+ + +      Y + +E    + A     
Sbjct: 1243 DARHEYTMTLGLPEFIRAKTNAANLSDARYKESW-RNLRAQGYKLTIEALPFQAARASGD 1301

Query: 5720 KQSDVAYRKD-AKEN---LHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSML 5775
              SD  YR D  KE    +   +V D P I+   +  +  SE++YR       +     +
Sbjct: 1302 IASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPM 1361

Query: 5776 GRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKAD 5835
                +  AK A  L+S   YR  + K         P+D ++    K A+ L SE++YK+D
Sbjct: 1362 DMVHLVHAKNAQALASDHDYRTQYHKFTAL-----PEDLKM-AWAKKAHALQSELRYKSD 1415

Query: 5836 LKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATE 5895
            L  +         S  M       +L S  +Y+KK +  K  + T+ D+ + +H K +  
Sbjct: 1416 LIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIK--FTTVVDSPDLVHAKNSYM 1473

Query: 5896 LQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEV 5955
              +   Y+    +   +  L  + P +  A+ +    S K YR  +E++  G     L+ 
Sbjct: 1474 HCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDA 1533

Query: 5956 TPALLHVKYATKIASEKEYRKDLEESIRGKGL----TEMEDTPDMLRAKNATQILNEKEY 6011
             P     + + +IAS+  Y+   E  +R +GL      ++D P M    N  ++ ++ EY
Sbjct: 1534 IP-FQTARASREIASDFRYK---EAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1589

Query: 6012 KRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIH 6071
            K+D     K R     + + P  ++A+ +  +AS + Y+Q         T   +   + H
Sbjct: 1590 KKDF---AKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQP----TCDPEQLGLRH 1642

Query: 6072 AQQVKNLSSQKKYKED 6087
            AQ+   L S  KYK D
Sbjct: 1643 AQKAHQLQSDVKYKSD 1658



 Score =  322 bits (825), Expect = 8e-87
 Identities = 379/1597 (23%), Positives = 669/1597 (41%), Gaps = 203/1597 (12%)

Query: 4793 PDMVEMVTAKDSQKKVSEIDYRLRLHEW----ICHPDLQVNDHVRKVTDQISDIVYKDDL 4848
            P++V MV A+ S  +    DY     +     +  P  Q     +K     S + YK   
Sbjct: 141  PEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQ---RAKKANQLASQVEYKRGH 197

Query: 4849 NWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKL-VTDTPVYVQAVKSGK 4907
            +        V DTPE+L +K    L+ D++Y     + R         TP Y  A ++ +
Sbjct: 198  DERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANE 257

Query: 4908 QLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGD- 4966
              SD  YH  Y   +RG   P      +         + ++ Y          +R  G  
Sbjct: 258  LASDVRYHQQYQKEMRGMAGPAIGAEGI------LTRECADQYGQGYPEEYEEHRGKGSF 311

Query: 4967 ----TPHFKHIKDTRYMSSYFKYKEAYEHTK--AYGYTLGPKD-VPFVHVRRVNNVTSER 5019
                TP +++ K    ++S  KY++ +   K  A+ ++L  +D +     + VN + SE 
Sbjct: 312  PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371

Query: 5020 LYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFK-MQGHMISLPYTPQVIH 5078
             Y++     +       +TP+ R V K  +  S+  YK ++   M+G    +    + +H
Sbjct: 372  EYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLH 431

Query: 5079 CRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRD--- 5135
               VG + S++ YK D +             D+V   +   L  +Y    K   ++D   
Sbjct: 432  AMKVGSLASNVAYKADYK------------HDIVDYNYPATLTPSYQTAMKLVPLKDANY 479

Query: 5136 -------KYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQ 5188
                   KY  V DTP+  + +     LS + YRA  +K K  +T   D P L++AK   
Sbjct: 480  RQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNA 539

Query: 5189 KLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPD 5247
            KL S+  Y E   K +           +L  AK   ++ S  KYK +YEK K K     D
Sbjct: 540  KLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTAD 599

Query: 5248 TPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMS 5307
            + +L   + A  + S++ YK+ F+++K ++H   D ++I + +K     S + Y++    
Sbjct: 600  SRLLHSLQIAKMS-SEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRK---- 654

Query: 5308 QLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYS 5367
            +L  +  +P+  +    +      S+++YK DL W+KG+G     + +   A+K   L S
Sbjct: 655  KLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS 714

Query: 5368 KYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHL 5427
            +  Y++  +  K  F  V DS    H K + +L +   Y+A  EQ   +Y +  DEP  L
Sbjct: 715  EKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFL 772

Query: 5428 LAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPR 5486
             A+     +S+  Y+ ++E  K K F   +D+   L         S++ YK +Y +++ +
Sbjct: 773  QARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGK 832

Query: 5487 --GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTN 5544
              G   +     + H  ++    S+L+YK+ ++  KS C +  D VH+  A+ A  + T+
Sbjct: 833  LIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATD 892

Query: 5545 LDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVL 5604
            + YK      + H+   P       A K+   QSD +Y+ D +++KG     T   N   
Sbjct: 893  VGYKTA----EHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQ 948

Query: 5605 ALRNTLIESDLKYKE----------------------------KHVKERGTC---HAVP- 5632
            A +   + S+ KY++                            +  +E+G     H  P 
Sbjct: 949  AKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPT 1008

Query: 5633 -DTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKK 5691
             D P++LLAK  +  +SE +YK+   K L  G Y    +       K   + +SD  YK+
Sbjct: 1009 ADLPEVLLAKLNAMNISETRYKESWSK-LRDGGYKLRLDALPFQAAKASGEIISDYKYKE 1067

Query: 5692 KFVKEKGKSNYSIMLEPP-EVKHAMEVAKKQSDVAYRKD---AKENLH------------ 5735
             F K KG+   S  LE    + H++     QSDV Y+K    +K   H            
Sbjct: 1068 AFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAK 1127

Query: 5736 -----------------YTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLGRP 5778
                             YT++A+   +  A +A K  SE  YR+           + G  
Sbjct: 1128 KAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTL 1187

Query: 5779 DIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKA---D 5835
            +IE  KKA++L S+ KYR++    K       P         K +N + +E  YKA   D
Sbjct: 1188 EIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHA----KFSNQITNERLYKAAGED 1243

Query: 5836 LKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYE--KSKGHYHTIPDNLEQLHLKEA 5893
             +  +     + E   +    N + L+ + +YK+ +   +++G+  TI + L     + +
Sbjct: 1244 ARHEYTMTLGLPE--FIRAKTNAANLSDA-RYKESWRNLRAQGYKLTI-EALPFQAARAS 1299

Query: 5894 TELQSIVKYKEKYEKERGK---PMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNL 5950
             ++ S   Y+  + KERGK   P    + P     +   Q+QS  +YR+    S    +L
Sbjct: 1300 GDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHL 1359

Query: 5951 TGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKE 6010
                V   L+H K A  +AS+ +YR    +       T + +   M  AK A  + +E  
Sbjct: 1360 PMDMVH--LVHAKNAQALASDHDYRTQYHK------FTALPEDLKMAWAKKAHALQSELR 1411

Query: 6011 YKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEII 6070
            YK DL   +  +G+  +A  +P    A+ A ++ S+ KY++  +  K  FT+VVD+P+++
Sbjct: 1412 YKSDL---IGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIK--FTTVVDSPDLV 1466

Query: 6071 HAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKG-- 6128
            HA+      +++ Y+    +S+  Y  + D P+  R R N  + S   Y+   + ++   
Sbjct: 1467 HAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGS 1526

Query: 6129 --------KITVVQDTPEI---LRVKE-------------------NQKNFSSV------ 6152
                         + + EI    R KE                     K+F +V      
Sbjct: 1527 YDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSD 1586

Query: 6153 -LYKEDVSPGTAIGKT----PEMMRVKQTQDHISSVKYKEAIGQGTPIPDLPEVKRVKET 6207
              YK+D +   +   +    P +++ K++Q   S V Y++ + Q T  P+   ++  ++ 
Sbjct: 1587 NEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKA 1646

Query: 6208 QKHISSVMYKENL----GTGIPTTVTPEIERVKRNQE 6240
             +  S V YK +L    G G     + ++E  +R  E
Sbjct: 1647 HQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAE 1683



 Score =  307 bits (787), Expect = 2e-82
 Identities = 385/1633 (23%), Positives = 673/1633 (41%), Gaps = 246/1633 (15%)

Query: 5109 PDMVRSRHLRKLWSNYLYTDKARKMRDKYKV-VLDTPEYRKVQELKTHLSELVYRAAGKK 5167
            P++VR    RK      YT+   + R K     + TP Y++ ++     S++ Y+    +
Sbjct: 141  PEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199

Query: 5168 QKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQTTALKHAKDVKDMV 5226
            + S F++V DTP+LLR+K G +LQS   Y E   ++R         T A + AK   ++ 
Sbjct: 200  RISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELA 259

Query: 5227 SEKKYKIQYEK-------------------MKDKYT----------------PVPDTPIL 5251
            S+ +Y  QY+K                     D+Y                 P   TP  
Sbjct: 260  SDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAY 319

Query: 5252 IRAKRAYWNASDLRYKETFQKTKGK--YHTV--KDALDIVYHRKVTDDISKIKYKENYMS 5307
              AK+A+  ASD++Y++ F K KG   YH++  +D L +   + V   +S+++YK++  S
Sbjct: 320  QNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLES 379

Query: 5308 QLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLT-----WLKGIGC-------------- 5348
              G   +  + P+  +   ++   SD KYKE+         +G+G               
Sbjct: 380  SRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLA 439

Query: 5349 --------YAYDTPDF----TLAEKNKTLYSKYKYKEVFERTKSD---FKYVADSPINRH 5393
                    Y +D  D+    TL    +T       K+   R   D   +  V D+P    
Sbjct: 440  SNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQ 499

Query: 5394 FKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK-F 5452
             K   Q ++   YRADYE+ K  Y L  D P+ + AKT     S++KY++ +EK+K K F
Sbjct: 500  AKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGF 559

Query: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKY 5512
               +D    L      +  S+I YK EY K K +   T      LLH  ++    S+++Y
Sbjct: 560  EMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSR--LLHSLQIAKMSSEVEY 617

Query: 5513 KEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAK 5572
            K+ ++ +K+   +  D V+I+ AK A  + ++LDY+K+       +   P+      A K
Sbjct: 618  KKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLH----EYTVLPEDMKTQWAKK 673

Query: 5573 SSLQQSDFEYKLDREFLKGCK---------------------------------LSVTDD 5599
            +   QS+ +YK D  ++KG                                    SVTD 
Sbjct: 674  AYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDS 733

Query: 5600 KNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKH 5659
                 A ++  ++S + YK  + +         D P  L A+  +  +SE  YK   +  
Sbjct: 734  SQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQ 793

Query: 5660 LAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLE-PPEVKHAMEVA 5718
             A+G    L ++   +  K      S+  YK+ + + +GK   +  ++   ++ H+++++
Sbjct: 794  KAKGFELRL-DSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMS 852

Query: 5719 KKQSDVAYRK---DAKENLH-----------------------------YTTVADRPDIK 5746
            K QS++ Y+K   D K   H                             +T +     ++
Sbjct: 853  KLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVE 912

Query: 5747 KATQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKT 5806
             A +A    S+ +YRA  +     G    G  ++E AKKA +L S+ KYR++ D  K  +
Sbjct: 913  WAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTS 972

Query: 5807 PKYNPKDSQLYKVMKDANNLASEVKYKA---DLKKLHKPVTDMKESLIMNHVLNTSQLAS 5863
             K  P+  Q     + +   A +  Y+    ++K  + P  D+ E L+    LN   ++ 
Sbjct: 973  IKDTPEMVQA----RISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAK--LNAMNISE 1026

Query: 5864 SYQYKKKYEKSK-GHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTY 5922
            + +YK+ + K + G Y    D L     K + E+ S  KYKE +EK +G+ +        
Sbjct: 1027 T-RYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1085

Query: 5923 ITAKES---QQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLE 5979
            I+   S     +QS   Y+K +E S K +    L++  AL+H K A  +AS ++Y+  L 
Sbjct: 1086 ISLAHSVYATSLQSDVNYKKGFEHS-KAQFHLPLDMA-ALVHAKKAQTLASNQDYKHPLP 1143

Query: 5980 ESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARN 6039
            +       T + +   +  AK A ++ +E  Y+ DL      RG+  +   T +    + 
Sbjct: 1144 Q------YTSLAEDLRLSCAKKAHKLQSENLYRSDLNFM---RGVACVIPGTLEIEGRKK 1194

Query: 6040 ATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVL 6099
            A+++ S+ KY+Q     K  +T+V DTP ++HA+    +++++ YK   E +   Y   L
Sbjct: 1195 ASELISESKYRQHPHSFK--YTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTL 1252

Query: 6100 DTPEIQRVRENQKNFSLLQYQCDLKNSKG---KITVVQDTPEILRVKENQKNFSSVLYKE 6156
              PE  R + N  N S  +Y+   +N +    K+T+  +       + +    S  LY+ 
Sbjct: 1253 GLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTI--EALPFQAARASGDIASDFLYRH 1310

Query: 6157 DV--SPGTAIGKTPEMMRVKQTQDHISSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSV 6214
            D     G  IG  P+ +R                        D P ++  +   +  S +
Sbjct: 1311 DFVKERGKLIG--PQSVR------------------------DDPRIQHCRRMGQLQSEL 1344

Query: 6215 MYKENLGTGIPTTVTP----EIERVKRNQENFSSVLYKENLGKGIPTPITPEMERVKRNQ 6270
             Y+    +       P     +   K  Q   S   Y+    K    P   +M   K+  
Sbjct: 1345 QYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAH 1404

Query: 6271 ENFSSVLYKENM----GKGTPLAVTPEMERVKHNQENISSVLYKENVGKATATPV--TPE 6324
               S + YK ++    G G     +P+ME  K   E IS   Y++       T V  +P+
Sbjct: 1405 ALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPD 1464

Query: 6325 MQRVKRNQENISSVLYK----ENLGKATPTPFTPEMERVKRNQENFSSVLYKENMRKATP 6380
            +   K +  + +  +Y+    E+L + T  P  P+  R + N  + S  +Y+ +  +   
Sbjct: 1465 LVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRA 1524

Query: 6381 TPVTPEMER-----AKRNQENISSVLYSDSFRKQIQGKAAY--VLDTPEMRRVRETQRHI 6433
                  ++      A+ ++E  S   Y ++F +    +  Y  V D P M+      R  
Sbjct: 1525 GSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQ 1584

Query: 6434 STVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYRGIQRKVVEMEQKRNDQDQE 6493
            S  +Y +DF K +  F      P   + K++ Q  SD++YR        + Q   D +Q 
Sbjct: 1585 SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYR------QPLPQPTCDPEQ- 1637

Query: 6494 TITGLRVWRTNPGSVFDYDPAEDNIQSRSL-----HMINVQAQRRSREQSRSASALSISG 6548
               GLR  +       D     D   +R +         V+  RR+ E + +A  L + G
Sbjct: 1638 --LGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELA-NARGLGLQG 1694

Query: 6549 GEEKSEHSEAPDH 6561
                +E  EA DH
Sbjct: 1695 AYRGAEAVEAGDH 1707



 Score =  282 bits (721), Expect = 9e-75
 Identities = 349/1533 (22%), Positives = 614/1533 (40%), Gaps = 199/1533 (12%)

Query: 5038 TPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQV 5097
            TP  ++ KK  +  S++ YK    +      ++  TP+++  +    + SD++Y ED + 
Sbjct: 175  TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ 234

Query: 5098 LKGFGCF-LYDTPDMVRSRHLRKLWSNYLYTDKARK-MRDKYKVVLDTPEYRKVQELKTH 5155
             +G G F    TP    ++   +L S+  Y  + +K MR      +        +    +
Sbjct: 235  QRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294

Query: 5156 LSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKER--PHHHA--GN 5211
                       + K  F ++  TP    AK+  +L S   Y +   K +   H+H+    
Sbjct: 295  GQGYPEEYEEHRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353

Query: 5212 QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQ 5271
                LK A+ V  +VSE +YK   E  +       +TP      +     SD +YKE +Q
Sbjct: 354  DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQ 413

Query: 5272 K-TKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDT 5330
               +G+Y  V      ++  KV    S + YK +Y   +  +         +        
Sbjct: 414  NHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVP 473

Query: 5331 VSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPI 5390
            + D  Y++ +  LK       DTP    A+ N    S   Y+  +E+ K ++    D P 
Sbjct: 474  LKDANYRQSIDKLKYSS--VTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQ 531

Query: 5391 NRHFKYATQLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSK 5449
                K   +L +E KY+  +E+ K K + + +D    L AK +G+  S IKY++ YEK+K
Sbjct: 532  LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591

Query: 5450 DKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSD 5509
             K     D+   L + ++ K  S++ YK  + ++K R +  + D   + H +K +   SD
Sbjct: 592  GKAMGTADS-RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPM-DMVNIRHAKKAQTLASD 649

Query: 5510 LKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQ 5569
            L Y+    +     T+ P+ +  + AK AY + + L YK      K     T    +  Q
Sbjct: 650  LDYR----KKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQ 705

Query: 5570 AAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCH 5629
            A K+    S+  Y+   + LK    SVTD      A ++  ++S + YK  + +      
Sbjct: 706  AKKAGQLVSEKNYRQRVDELKFT--SVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYT 763

Query: 5630 AVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNY 5689
               D P  L A+  +  +SE  YK   +   A+G    L ++   +  K      S+  Y
Sbjct: 764  ISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRL-DSLTFLAAKAKRDLASEVKY 822

Query: 5690 KKKFVKEKGKSNYSIMLE-PPEVKHAMEVAKKQSDVAYRK---DAKENLH---------- 5735
            K+ + + +GK   +  ++   ++ H+++++K QS++ Y+K   D K   H          
Sbjct: 823  KEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVH 882

Query: 5736 -------------------YTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLG 5776
                               +T +     ++ A +A    S+ +YRA  +     G    G
Sbjct: 883  ARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATG 942

Query: 5777 RPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQ-----------LYKVMKD--- 5822
              ++E AKKA +L S+ KYR++ D  K  + K  P+  Q           LY+   +   
Sbjct: 943  SLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIK 1002

Query: 5823 ------------------ANNLASEVKYKADLKKLHKPVTDMK-ESLIMNHVLNTSQLAS 5863
                              A N+ SE +YK    KL      ++ ++L       + ++ S
Sbjct: 1003 HHYTPTADLPEVLLAKLNAMNI-SETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1061

Query: 5864 SYQYKKKYEKSKGHY---HTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETP 5920
             Y+YK+ +EK KG      ++ D++   H   AT LQS V YK+ +E  + +  L  +  
Sbjct: 1062 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMA 1121

Query: 5921 TYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEE 5980
              + AK++Q + S ++Y+    +       T L     L   K A K+ SE  YR DL  
Sbjct: 1122 ALVHAKKAQTLASNQDYKHPLPQ------YTSLAEDLRLSCAKKAHKLQSENLYRSDLN- 1174

Query: 5981 SIRG-----KGLTEME---------------------------DTPDMLRAKNATQILNE 6008
             +RG      G  E+E                           DTP++L AK + QI NE
Sbjct: 1175 FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNE 1234

Query: 6009 KEYKR-----------------------------DLELEVKGRGLNA----MANETPDFM 6035
            + YK                              D   +   R L A    +  E   F 
Sbjct: 1235 RLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQ 1294

Query: 6036 RARNATDIASQIKYKQSAEMEKANFT---SVVDTPEIIHAQQVKNLSSQKKYKEDAEKSM 6092
             AR + DIAS   Y+     E+       SV D P I H +++  L S+ +Y+  A  S 
Sbjct: 1295 AARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQ 1354

Query: 6093 SYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSV 6152
            + +   +D   +       KN   L    D +    K T + +  ++   K+     S +
Sbjct: 1355 AQFHLPMDMVHLVHA----KNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSEL 1410

Query: 6153 LYKEDVSPGTAIG----KTPEMMRVKQTQDHISSVKYKEAIG--QGTPIPDLPEVKRVKE 6206
             YK D+     IG    ++P+M   K+  + IS  KY++     + T + D P++   K 
Sbjct: 1411 RYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKN 1470

Query: 6207 TQKHISSVMYK----ENLGTGIPTTVTPEIERVKRNQENFSSVLYKENLGKGIPTPITPE 6262
            +  H +  MY+    E+L         P+  R + N  + S  +Y+ +  +         
Sbjct: 1471 SYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFR 1530

Query: 6263 MERV-----KRNQENFSSVLYKENMGKGTPLAV-------TPEMERVKHNQENISSVLYK 6310
            ++ +     + ++E  S   YKE   +   L +        P M+   +     S   YK
Sbjct: 1531 LDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYK 1590

Query: 6311 ENVGKATA----TPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVKRNQENF 6366
            ++  K+ +    +   P + + KR+Q+  S V Y++ L + T  P    +   ++  +  
Sbjct: 1591 KDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQ 1650

Query: 6367 SSVLYKENMRKATPTPVTP----EMERAKRNQE 6395
            S V YK ++        TP    ++E A+R  E
Sbjct: 1651 SDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAE 1683



 Score = 82.8 bits (203), Expect = 1e-14
 Identities = 114/487 (23%), Positives = 199/487 (40%), Gaps = 51/487 (10%)

Query: 6031 TPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEK 6090
            TP  +  R   +  S I  ++  E  K+ F   + + +   A   + L++++ Y     +
Sbjct: 70   TPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANERAYWTGYGE 129

Query: 6091 SMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITV-VQDTPEILRVKENQKNF 6149
              ++    L  PEI R+ E +K+    +Y  D +  +GK +     TP   R K+  +  
Sbjct: 130  GNAWCPGALPDPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLA 188

Query: 6150 SSVLYK----EDVSPGTAIGKTPEMMRVKQTQDHISSVKYKEAI----GQGT-PIPDLPE 6200
            S V YK    E +S  + +  TPE++R K      S V+Y E      G+G+ P    P 
Sbjct: 189  SQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248

Query: 6201 VKRVKETQKHISSVMY-----KENLGTGIPTTVTPEI---ERVKRNQENFSSVLYKENLG 6252
             +  K   +  S V Y     KE  G   P      I   E   +  + +    Y+E+ G
Sbjct: 249  YQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEE-YEEHRG 307

Query: 6253 KG-IPTPITPEMERVKRNQENFSSVLYKENMGK--------GTPLAVTPEMERVKHNQEN 6303
            KG  P  ITP  +  K+  E  S + Y+++  K          P      +++ +   + 
Sbjct: 308  KGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKL 367

Query: 6304 ISSVLYKENVGKATATPV----TPEMQRVKRNQENISSVLYKENL-----GKATPTPFTP 6354
            +S V YK+++  +    +    TP+ + V +  +  S   YKEN      G+        
Sbjct: 368  VSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDR 427

Query: 6355 EMERVKRNQENFSSVLYKENMRKAT-----PTPVTPEMERAKRNQENISSVLYSDSFRKQ 6409
                  +     S+V YK + +        P  +TP  + A +       V   D+  +Q
Sbjct: 428  RTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMK------LVPLKDANYRQ 481

Query: 6410 IQGKAAY--VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQD 6467
               K  Y  V DTP++ + +   + +S V Y  D+EK+K  +T     P   + K N + 
Sbjct: 482  SIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKL 541

Query: 6468 FSDINYR 6474
            FS++ Y+
Sbjct: 542  FSEVKYK 548


>gi|46049092 nebulin-related anchoring protein isoform C [Homo
            sapiens]
          Length = 1695

 Score = 1176 bits (3042), Expect = 0.0
 Identities = 615/1520 (40%), Positives = 969/1520 (63%), Gaps = 38/1520 (2%)

Query: 456  KNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHT-YKVHPDK--TKFTQVTDSPVLL 512
            + Y  +YE+ RGKG FP  IT  Y+  KK +Q      YK   D+  ++F+ V D+P LL
Sbjct: 155  EEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELL 214

Query: 513  QAQVNSKQLSDLNYKAKHESEKFKCHIPPD-TPAFIQHKVNAYNLSDNLYKQDWEKSKAK 571
            +++  ++  SD+ Y   +E ++ K   P   TPA+   K      SD  Y Q ++K    
Sbjct: 215  RSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQK---- 270

Query: 572  KFDIKVDAIPLLAAKAN-TKNTSDVM---YKKDYEKNKGKMIGVLSINDDPKMLHSLKVA 627
              +++  A P + A+   T+  +D     Y ++YE+++GK  G       P   ++ K  
Sbjct: 271  --EMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGK--GSFPAMITPAYQNAKKAH 326

Query: 628  KNQSDRLYKENYEKTKAKSMNYCETPKY------QLDTQLKNFSEARYKDLYVKDVLGHY 681
            +  SD  Y++++ K K  + +Y   P        Q  +  K  SE +YK+ Y   + G Y
Sbjct: 327  ELASDIKYRQDFNKMKGAA-HYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRY 385

Query: 682  VGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKLDQCKDHTYK 741
             G   D    H MKV +  S+ +YKA+Y+ D     +P T+T  Y+   KL   KD  Y+
Sbjct: 386  EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR 445

Query: 742  VHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVNAY 801
               DK K+++VTD+P ++QA++N +QLS +NY+A +E  K    +P D PQ ++ + NA 
Sbjct: 446  QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK 505

Query: 802  NLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSI 861
              S+  YK+ WEK+K K F++K+DA+ LLAAKA+ +  S++ YK++YEK+KGK +G    
Sbjct: 506  LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA-- 563

Query: 862  NDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHIL 921
              D ++LHSL+ AK  S+ EY+K +E+SKT +  P+DM+ +  AKK+Q +ASD+DY+  L
Sbjct: 564  --DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKL 621

Query: 922  HSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASDILNE 981
            H Y+  P+ +    AKKAY LQS+++YKAD  +WMKG GW+  GSL +E+AK+A  +++E
Sbjct: 622  HEYTVLPEDMKTQWAKKAYGLQSELQYKADL-AWMKGVGWLTEGSLNLEQAKKAGQLVSE 680

Query: 982  KKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAK 1041
            K YRQ  D LKFTS+ D+     +K +Q  +S +AYKA  E+ +H+Y +  D P F+QA+
Sbjct: 681  KNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQAR 740

Query: 1042 VNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVG 1101
             NA N+SE +YK+  ++   KG++LR D++   AAKA R  AS+V+YK+DYE+++GK++G
Sbjct: 741  ANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIG 800

Query: 1102 FQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVSNVNY 1161
             + +Q D ++ H + ++K+QS+ EYKK +E TKS+ +   DM ++V A+KAQ + ++V Y
Sbjct: 801  AKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGY 860

Query: 1162 KHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGD 1221
            K + HH+T LP  M +E +K    +QSDN Y+ D   WMKG+GW+  GSL+VE+ KKAG+
Sbjct: 861  KTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVK-WMKGMGWVATGSLNVEQAKKAGE 919

Query: 1222 ALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQF 1281
             ++EKKYRQHPD LKFTSI D+P MVQA+ +  Q  D LY+ +GE++KH YT + DLP+ 
Sbjct: 920  LISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEV 979

Query: 1282 LQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKG 1341
            L AK NA NIS+  YK  W  L   G  +  DA+P  AAKAS  I SDYKYKEA+EK KG
Sbjct: 980  LLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKG 1039

Query: 1342 KHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVAT 1401
            + +G RSL+DD  L H +    LQSD  YKK +E++K  +H P DM ++  AK AQ +A+
Sbjct: 1040 QMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLAS 1099

Query: 1402 NVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVK 1461
            N +YK PL  YT L + + L   +  +++QS+N+Y+ + N F++G+  +  G+LE+E  K
Sbjct: 1100 NQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN-FMRGVACVIPGTLEIEGRK 1158

Query: 1462 KAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPE 1521
            KA + ++E KYRQHP + K+T+V D+  ++ A+ + +  ++  YK  GE  +H+YT+   
Sbjct: 1159 KASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLG 1218

Query: 1522 LPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYE 1581
            LP+FI+AK NA N+SDA YK  W+   A+GY L  +A+P  AA++S +IASD  Y+  + 
Sbjct: 1219 LPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFV 1278

Query: 1582 KAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQ 1641
            K +GK +G  S++DDP++ H   + ++QS+ +Y++G  +S+ ++H P+DMV +  AK +Q
Sbjct: 1279 KERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQ 1338

Query: 1642 EVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEV 1701
             +A++ +YR  YH +T LP+ L +  ++ A  +QS+  YKSD    MKGIGW+ + S ++
Sbjct: 1339 ALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIGWLALRSPQM 1397

Query: 1702 EKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIH 1761
            E AKKAGE++SE KYR+ P+ +KFT  +D+ +    K++ ++ ++R+Y    + D  ++H
Sbjct: 1398 ESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLH 1454

Query: 1762 ---VMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDY 1818
               ++PD PD   +R+N + +SDK+Y+  WE+ +   YD R DAI  + ARASR+IASD+
Sbjct: 1455 RYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDF 1514

Query: 1819 KYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSV 1878
            +YK+A+ + +G  IG+RS++DDP++ HF+ V ++QSD EYKK + KS++ FH+  D   +
Sbjct: 1515 RYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGL 1574

Query: 1879 VAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWL 1938
            + AK+SQ++A++ +YR  +      P+ +    A+   Q+QSD +YK+D  +  +G+GW 
Sbjct: 1575 LQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSD-LNLTRGVGWT 1633

Query: 1939 PLGSLEAEKNKKAMEIISEK 1958
            P GS + E  ++A E+ + +
Sbjct: 1634 PPGSYKVEMARRAAELANAR 1653



 Score = 1087 bits (2812), Expect = 0.0
 Identities = 607/1646 (36%), Positives = 961/1646 (58%), Gaps = 92/1646 (5%)

Query: 109  KGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVS 168
            K   + S   TP    ++   + +S +  + DG+  K++ H D K+KD E A       +
Sbjct: 60   KNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLAN 119

Query: 169  KVLYKQNWEDTKDKYLLPPDA---PELVQAVKNTAMFSKKLYTEDWEADKSL-FYPYNDS 224
            +  Y   W    +     P A   PE+V+ V+      ++ YTED+E  +    +P   +
Sbjct: 120  ERAY---WTGYGEGNAWCPGALPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMIT 175

Query: 225  PELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENK 284
            P  +R  +A +  S V YK+G  E+ ++F+ + D P++  +K      S  +Y EDYE +
Sbjct: 176  PAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQ 235

Query: 285  IKGKWSE----TPCFEVANAR------------------------MNADNISTRK----- 311
             +GK S     TP +++A                           + A+ I TR+     
Sbjct: 236  -RGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294

Query: 312  ---YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASE 368
               Y E++E  + +  F    TP Y+  KKA   AS +KY++D+ K KG A Y+ LPA +
Sbjct: 295  GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQD 354

Query: 369  NPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLK 428
            N  L+Q                     A+S+N                 S+ KYK++Y  
Sbjct: 355  NLVLKQ---------------------AQSVN--------------KLVSENKYKENYQN 379

Query: 429  DILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQC 488
             + G Y G   D    H MKV +  S+  YKA+Y+ D     +P T+T  Y+   KL   
Sbjct: 380  HMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPL 439

Query: 489  KDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQ 548
            KD  Y+   DK K++ VTD+P ++QA++N++QLS +NY+A +E  K    +P D P  ++
Sbjct: 440  KDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVK 499

Query: 549  HKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKM 608
             K NA   S+  YK+ WEK+K K F++K+DA+ LLAAKA+ +  S++ YK++YEK KGK 
Sbjct: 500  AKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA 559

Query: 609  IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEAR 668
            +G      D ++LHSL++AK  S+  YK+ +E++K +       P   ++ +    ++  
Sbjct: 560  MGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR----FHLPMDMVNIRHAKKAQTL 611

Query: 669  YKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEA 728
              DL  +  L  Y    ED       K     S+  YKA+    KG  +  +      +A
Sbjct: 612  ASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQA 671

Query: 729  IKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPA 788
             K      +  Y+   D+ KFT+VTDS  +  A+ + +  S + YKA +E    +  I  
Sbjct: 672  KKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISK 731

Query: 789  DAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDY 848
            D P F+Q R NA NLS+ +YK  WE  KAK F++++D++  LAAKA     S+V YK+DY
Sbjct: 732  DEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDY 791

Query: 849  EKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKS 908
            E+S+GK+IGA  +  D +M HSL+ +K QS+ EY+K +E +K+     LDM+ +  A+K+
Sbjct: 792  ERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKA 851

Query: 909  QAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLE 968
            Q +A+DV YK   H ++  P  + V+ AKKAY LQSD +Y+AD   WMKG GWV  GSL 
Sbjct: 852  QHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLN 910

Query: 969  MEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKY 1028
            +E+AK+A ++++EKKYRQHPD LKFTSI+D P  VQ++I+  Q  D  Y+ +GE I H Y
Sbjct: 911  VEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHY 970

Query: 1029 NLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQY 1088
                DLP+ + AK+NA NISE  YK     L   GY LR DA+P +AAKA+ +  SD +Y
Sbjct: 971  TPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKY 1030

Query: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA 1148
            K+ +EK KG+M+G +SL+DD  L H +    +QSD  YKK +E +K++++ P DM  +V 
Sbjct: 1031 KEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVH 1090

Query: 1149 AKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPI 1208
            AKKAQ + SN +YKH L  YT L + + L  +K   ++QS+N+Y+ D  N+M+G+  +  
Sbjct: 1091 AKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL-NFMRGVACVIP 1149

Query: 1209 GSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDV 1268
            G+L++E  KKA + ++E KYRQHP + K+T++ D+P ++ AK + +  ++ LYKA GED 
Sbjct: 1150 GTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDA 1209

Query: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328
            +H+YTM+  LP+F++AK NA N+SD  YK  W +L A+G  +  +A+P  AA+AS +IAS
Sbjct: 1210 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1269

Query: 1329 DYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV 1388
            D+ Y+  + K +GK +G +S++DDP++ H   + +LQS+ +Y++   +++  +H P DMV
Sbjct: 1270 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMV 1329

Query: 1389 SITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIG 1448
             +  AK AQ +A++ +Y+   H +T LP+ + +   +  + +QS+  YK +    +KGIG
Sbjct: 1330 HLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIG 1388

Query: 1449 WIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVE 1508
            W+ + S ++E  KKAG+ ++E KYR+ PD++KFT+V DS  +V A+++    ++  Y+  
Sbjct: 1389 WLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSG 1448

Query: 1509 GEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSR 1568
              +  H+YT+ P+ P F +A++NAL++SD  Y+  W++T A  YD R DAIP   A++SR
Sbjct: 1449 DAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASR 1508

Query: 1569 NIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTP 1628
             IASD +YKEA+ + +G Q+G+ S+ DDP++ H++NV ++QSD EYKK +  S++++H+ 
Sbjct: 1509 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1568

Query: 1629 LDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWM 1688
             D   +  AK+SQ++A++ +YRQ     T  P+ L + H++ A Q+QSD  YKSD  N  
Sbjct: 1569 TDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDL-NLT 1627

Query: 1689 KGIGWVPIESLEVEKAKKAGEILSEK 1714
            +G+GW P  S +VE A++A E+ + +
Sbjct: 1628 RGVGWTPPGSYKVEMARRAAELANAR 1653



 Score = 1035 bits (2675), Expect = 0.0
 Identities = 578/1564 (36%), Positives = 916/1564 (58%), Gaps = 76/1564 (4%)

Query: 1176 DLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVK--KAGDALNEK---KYRQ 1230
            D E + N   + ++  Y   Y    +G  W P    D E V+  +A  +L E+    Y Q
Sbjct: 107  DKEGAPNRQPLANERAYWTGYG---EGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQ 163

Query: 1231 HPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYN 1290
                  F +++ +P   +AK+  +  S + YK   ++   +++   D P+ L++K  A  
Sbjct: 164  PRGKGSFPAMI-TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQL 222

Query: 1291 ISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSK----GKHVGF 1346
             SDV Y  D+     KG+           AK +  +ASD +Y + Y+K      G  +G 
Sbjct: 223  QSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGA 282

Query: 1347 RSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV-SITAAKMAQDVATNVNY 1405
              +        Y         + Y + YE  +     P  +  +   AK A ++A+++ Y
Sbjct: 283  EGILTRECADQY--------GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKY 334

Query: 1406 KQPLH------HYTYLP--DAMSLEHTRNVNQIQSDNVYKDEYNSFLKG----------- 1446
            +Q  +      HY  LP  D + L+  ++VN++ S+N YK+ Y + ++G           
Sbjct: 335  RQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRT 394

Query: 1447 IGWIPIGSLEVEKVKKAGDA------------------------LNERKYRQHPDTVKFT 1482
            +  + +GSL      KA                           L +  YRQ  D +K++
Sbjct: 395  LHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 454

Query: 1483 SVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKA 1542
            SV D+  +V A+ N +QLS +NY+ + EK K  YT+  ++PQ ++AK NA   S+  YK 
Sbjct: 455  SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 514

Query: 1543 DWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHY 1602
             W+KT  KG++++ DA+ ++AAK+S  +AS+ KYKE YEK KGK +G      D +L+H 
Sbjct: 515  GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 570

Query: 1603 MNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDA 1662
            + +AK+ S+ EYKKG+E SKT++H P+DMV++  AKK+Q +A++ +YR+  H YT+LP+ 
Sbjct: 571  LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 630

Query: 1663 LNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEK 1722
            +  + ++ A  +QS+  YK+D   WMKG+GW+   SL +E+AKKAG+++SEK YRQ  ++
Sbjct: 631  MKTQWAKKAYGLQSELQYKADLA-WMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDE 689

Query: 1723 LKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDK 1782
            LKFT   D+ +    K ++       Y     +      +  D P  L +R N   +S+K
Sbjct: 690  LKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEK 749

Query: 1783 LYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPK 1842
            LYK+ WE +K KG++LR D++   AA+A RD+AS+ KYK+ YE+++GK IG + ++ D +
Sbjct: 750  LYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQ 809

Query: 1843 LVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNM 1902
            + H +Q++K+QS+ EYKKG+E +K+  H  +DM+ +V A+K+Q +AT+  Y+   H +  
Sbjct: 810  MSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTA 869

Query: 1903 LPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQ 1962
            LP  M  E AK    +QSDNQY+AD   +MKG+GW+  GSL  E+ KKA E+ISEKKYRQ
Sbjct: 870  LPTDMKVEWAKKAYGLQSDNQYRAD-VKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQ 928

Query: 1963 HPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP--DIPQIILAKANA 2020
            HPD LK++++ D+  MV A+ +     + LY++  + +  K H  P  D+P+++LAK NA
Sbjct: 929  HPDALKFTSIKDTPEMVQARISYTQAVDRLYRE--QGENIKHHYTPTADLPEVLLAKLNA 986

Query: 2021 INMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRS 2080
            +N+S+  YK S  + +  GY LR DA+P +AAKAS +I SDYKYK  +EK KG+M+G RS
Sbjct: 987  MNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRS 1046

Query: 2081 LEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHL 2140
            LEDD  L HS+    +QSD  YKK +E++K  +H P DM ++  AK AQ   +N +YKH 
Sbjct: 1047 LEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHP 1106

Query: 2141 IHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYAS 2200
            + +Y  L + + +   +  +++QS+N Y+ D N + +G+     G+LE+E  KKA+E  S
Sbjct: 1107 LPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN-FMRGVACVIPGTLEIEGRKKASELIS 1165

Query: 2201 DQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQA 2260
            + KYRQHP +F++  +TD+ +++ AK +    N+ LY       + +  +    P+ ++A
Sbjct: 1166 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA 1225

Query: 2261 KQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHV 2320
            K N    S   YK  W     +GY L ++A+  Q A+AS DIASD+ Y+  + K+ G  +
Sbjct: 1226 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI 1285

Query: 2321 GFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVD 2380
            G +S++DDP++     + ++QSE +Y++     + +F  P+DM+ +V AK  Q L SD D
Sbjct: 1286 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD 1345

Query: 2381 YKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASE 2440
            Y+   H++T LP+   +  AKK + LQSE  YKSDL  ++GIGW  L S + E  K+A E
Sbjct: 1346 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1405

Query: 2441 IISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDI 2500
            +ISE KYR+ PD  KFT++ D+ D+V AK +  + ++R+YR    +   +  ++PD PD 
Sbjct: 1406 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1465

Query: 2501 VLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLG 2560
              A+ N ++ SDK+YR  +E+ +   YD  +DAIP + A+ASREIAS+++YKE F +  G
Sbjct: 1466 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1525

Query: 2561 HHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVS 2620
              IG R+++DDP+M   ++V ++QSD EYKKDF K +++F S  D  G++ AK+ Q L S
Sbjct: 1526 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1585

Query: 2621 DVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKR 2680
            DV Y+  L Q TC P+Q  + HA++A+ LQSD  YKSDL   +G+GW   GS + E  +R
Sbjct: 1586 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR 1645

Query: 2681 ATQI 2684
            A ++
Sbjct: 1646 AAEL 1649



 Score = 1021 bits (2641), Expect = 0.0
 Identities = 601/1615 (37%), Positives = 942/1615 (58%), Gaps = 85/1615 (5%)

Query: 2108 NTKTS-YHTPADMLSVTAAKDAQANITNTN----YKHLIHKYILLPDAMNIELTRNMNRI 2162
            NT TS YHTP + L+V    +A + I +       K + H  +   D    E   N   +
Sbjct: 62   NTFTSVYHTPLN-LNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDK---EGAPNRQPL 117

Query: 2163 QSDNEYKQDYNEWYKGLGWSPAGSLEVE-----KAKKATEYASDQKYRQHPSNFQFKKLT 2217
             ++  Y   Y E   G  W P    + E     +A+K+      + Y Q      F  + 
Sbjct: 118  ANERAYWTGYGE---GNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAM- 173

Query: 2218 DSMDMVLAKQNAHTMNKHLYTIDWNKDK----TKIHVMPDTPDILQAKQNQTLYSQKLYK 2273
                +  A Q A   N+    +++ +      ++   + DTP++L++K    L S   Y 
Sbjct: 174  ----ITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYT 229

Query: 2274 LGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVL 2333
              +E+   KG    +   + Q+AK + ++ASD +Y Q Y+K++    G        + +L
Sbjct: 230  EDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMR---GMAGPAIGAEGIL 286

Query: 2334 SMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQELVSDVDYKNYLHQ----- 2387
            +   A  Q  + Y +++E+ + K S P  +      AKK  EL SD+ Y+   ++     
Sbjct: 287  TRECAD-QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAA 345

Query: 2388 -WTCLPDQNDVV--QAKKVYELQSENLYKSDLE-----WLRGIGWS-------PLGSLEA 2432
             +  LP Q+++V  QA+ V +L SEN YK + +        G+G          +GSL +
Sbjct: 346  HYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLAS 405

Query: 2433 EKNKRAS---EIIS---------------------EKKYRQPPDRNKFTSIPDAMDIVLA 2468
                +A    +I+                      +  YRQ  D+ K++S+ D   IV A
Sbjct: 406  NVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQA 465

Query: 2469 KTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYD 2528
            K NA+  S   YR  ++K+K    +  D P +V AK N    S+  Y+ G+E+ K KG++
Sbjct: 466  KINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFE 525

Query: 2529 LPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDRE 2588
            + +DA+ + AAKAS E+AS  KYKE + K  G  +G      D +++ S+ +AK+ S+ E
Sbjct: 526  MKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVE 581

Query: 2589 YKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYD 2648
            YKK FE+ KT+F  P+DM+ +  AKK QTL SD+DY+  LH++T LP+      A++AY 
Sbjct: 582  YKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYG 641

Query: 2649 LQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPM 2708
            LQS+  YK+DL W+KG+GW+T GSL  E+ K+A Q++S+  YRQ  D+ KF+S+ DS  M
Sbjct: 642  LQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQM 701

Query: 2709 VLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRK 2768
              AK +    +   Y    ++      I  D P  L A+ N  N SEKLYK   E  K K
Sbjct: 702  EHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAK 761

Query: 2769 GYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQS 2828
            G+++R+D++   AAKA RD+ASE KYKE Y +  G  IGA+ ++ D +M  S+ ++K+QS
Sbjct: 762  GFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQS 821

Query: 2829 DREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQ 2888
            + EYKK FE  K++    +DM+ +V A+K Q L +DV YK   H +T LP    V  A++
Sbjct: 822  ELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKK 881

Query: 2889 AYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDS 2948
            AY LQSDN Y++D++WM+G+GWV+ GSL+VE+ K+A E++S+K YRQ PD  KFTS+ D+
Sbjct: 882  AYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDT 941

Query: 2949 LEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEA 3008
             E V A+ +      RLY E  +  K       D PE++LA+ N +N SET YK +  + 
Sbjct: 942  PEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKL 1001

Query: 3009 KKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAK 3068
            +  GY LR DA+P  AAKAS ++ISDYKYK+ + K  G  +G+R++EDD  +  S++   
Sbjct: 1002 RDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATS 1061

Query: 3069 IQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIH 3128
            +QSD  YKK FE  K +F  P+DM  +V AKK QTL S+ DYK+ L ++T L +   +  
Sbjct: 1062 LQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSC 1121

Query: 3129 ARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSV 3188
            A++A+ LQS+N+Y+SDL ++RG+  V  G++++   K+A+E++S++ YRQ P   K+T+V
Sbjct: 1122 AKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAV 1181

Query: 3189 TDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAM 3248
            TD+   + AK +    N+RLY  A +  + +  +    PE + A+ N  N S++ Y+++ 
Sbjct: 1182 TDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESW 1241

Query: 3249 EEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLH 3308
               + +GY L  +A+P  AA+AS DIASD+ Y+  + K+ G  IG ++V DDP+I     
Sbjct: 1242 RNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRR 1301

Query: 3309 IAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQND 3368
            + ++QS+ +Y++     + ++  P+DM+ +V AK  Q L SD DY+   H++  LP+   
Sbjct: 1302 MGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLK 1361

Query: 3369 IIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKF 3428
            +  A+KA+ LQS+  YKSDL  MKGIGW+ + S ++  AK+AGEL+S+T YR++P+++KF
Sbjct: 1362 MAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKF 1421

Query: 3429 TSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIH---VMPDTPEIMLAKLNRINYSDK 3485
            T++ D+P+ V AKN+ ++ N+R+Y      D +++H   ++PD P+   A+LN ++ SDK
Sbjct: 1422 TTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDK 1478

Query: 3486 LYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPK 3545
            +Y+ + E+++   YD RLDAIP Q A+ASR+IASD++YKE + +  G  IG R++ DDP+
Sbjct: 1479 VYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPR 1538

Query: 3546 MMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTC 3605
            M   ++V ++QSD EYKK+F K +++F S  D  G++ AK+ Q L SD+ Y+ PL + TC
Sbjct: 1539 MKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTC 1598

Query: 3606 LPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDR 3660
             P+Q  +  A+KA+ LQSD  YKSDL   RG+GW P GS +VE  +RA E+ + R
Sbjct: 1599 DPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANAR 1653



 Score = 1004 bits (2595), Expect = 0.0
 Identities = 571/1519 (37%), Positives = 894/1519 (58%), Gaps = 69/1519 (4%)

Query: 2433 EKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIH 2492
            E  K   E  +E  Y QP  +  F ++         K N +  S   Y+   D+  ++  
Sbjct: 148  EARKSLGEEYTED-YEQPRGKGSFPAMITPAYQRAKKAN-QLASQVEYKRGHDERISRFS 205

Query: 2493 IMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYK 2552
             + DTP+++ +KA     SD  Y   YE+ + KG    +     + AK + E+AS+ +Y 
Sbjct: 206  TVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYH 265

Query: 2553 EGFRKQL----GHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLG 2608
            + ++K++    G  IGA  I               Q  + Y +++E+ + K S P  +  
Sbjct: 266  QQYQKEMRGMAGPAIGAEGI--------LTRECADQYGQGYPEEYEEHRGKGSFPAMITP 317

Query: 2609 VVL-AKKCQTLVSDVDYKNYLHQ------WTCLPDQSDVI--HARQAYDLQSDNLYKSDL 2659
                AKK   L SD+ Y+   ++      +  LP Q +++   A+    L S+N YK + 
Sbjct: 318  AYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENY 377

Query: 2660 Q-----WLKGIGW-------MTSGSLED-------------EKNKRATQI---------- 2684
            Q       +G+G        M  GSL               + N  AT            
Sbjct: 378  QNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLV 437

Query: 2685 -LSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEV 2743
             L D  YRQ  D+ K+SS+ D+  +V AK NA  ++H  Y   ++K+K    +  D P++
Sbjct: 438  PLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQL 497

Query: 2744 LLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLG 2803
            + AK N   +SE  YK G E+ K KG++M++DA+ + AAKAS ++AS  KYKE Y K  G
Sbjct: 498  VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 557

Query: 2804 HHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVS 2863
              +G      D +++ S+ +AK+ S+ EYKK FE+ KT+F  P+DM+ +  AKK QTL S
Sbjct: 558  KAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLAS 613

Query: 2864 DVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKR 2923
            D+DY+  LH++T LP+      A++AY LQS+  YK+DL WM+G+GW++ GSL++E+ K+
Sbjct: 614  DLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKK 673

Query: 2924 ATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDT 2983
            A +++S+K YRQ  D  KFTSVTDS +   AK +    +   Y    ++   Q  I  D 
Sbjct: 674  AGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 733

Query: 2984 PEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRK 3043
            P  + AR N  N SE LYK + E  K KG++LR D++  +AAKA RD+ S+ KYK+ Y +
Sbjct: 734  PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYER 793

Query: 3044 QLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQT 3103
              G  IGA++++ D +M  S+ ++K+QS+ EYKK FE  K++    +DM+ +V A+K Q 
Sbjct: 794  SRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQH 853

Query: 3104 LVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVK 3163
            L +DV YK   H +T LP    V  A++AY LQSDN Y++D++W++G+GWV  GS++V +
Sbjct: 854  LATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQ 913

Query: 3164 CKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIM 3223
             K+A E++S+  YRQ PD LKFTS+ D+ E V A+ +      RLY E  +  K      
Sbjct: 914  AKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPT 973

Query: 3224 PDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEA 3283
             D PE++LA+ N +N SE+ Y+++  + +  GY LR DA+P  AAKAS +I SDYKYKEA
Sbjct: 974  ADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEA 1033

Query: 3284 YRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKK 3343
            + K  G  +G+R++ DD  +  S++   +QSD  YKK FE  K ++  P+DM  +V AKK
Sbjct: 1034 FEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKK 1093

Query: 3344 CQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLE 3403
             QTL S+ DYKHPL ++  L +   +  A+KA+ LQS+NLY+SDL +M+G+  V   +LE
Sbjct: 1094 AQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLE 1153

Query: 3404 VVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTI 3463
            +   K+A EL+S++ YRQ P + K+T++TDTP  + AK +    N+RLY  A ++ +   
Sbjct: 1154 IEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEY 1213

Query: 3464 HVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKY 3523
             +    PE + AK N  N SD  YK +    + +GY L ++A+P QAA+AS DIASD+ Y
Sbjct: 1214 TMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLY 1273

Query: 3524 KEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVL 3583
            +  + K+ G  IG ++++DDP++     + ++QS+ +Y++     + +F  P+DM+ +V 
Sbjct: 1274 RHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVH 1333

Query: 3584 AKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIG 3643
            AK  Q L SD DY+   H++T LP+   +  A+KA+ LQS+  YKSDL  ++GIGW+ + 
Sbjct: 1334 AKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALR 1393

Query: 3644 SVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADK 3703
            S ++E  K+AGE++S+ KYR+  D +KFT + D+P++V AKN+ +  ++ +Y      D 
Sbjct: 1394 SPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDA 1450

Query: 3704 TSIH---VMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDI 3760
             S+H   ++PD PD   A+ N+ ++S K+Y   W++++   YD R DAI  ++A+ASR+I
Sbjct: 1451 ESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREI 1510

Query: 3761 ASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVD 3820
            ASD++YKEA+ + +G  IG +S++DDP++   ++ G++QS+ EYKK+F K +++F S  D
Sbjct: 1511 ASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTD 1570

Query: 3821 MLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGI 3880
               +L AK+ Q L +D+ YR  L + TC P+Q  +  A+KA+ LQSD  YK+DL   RG+
Sbjct: 1571 QPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGV 1630

Query: 3881 GWMPQGSPEVLRVKNAQNI 3899
            GW P GS +V   + A  +
Sbjct: 1631 GWTPPGSYKVEMARRAAEL 1649



 Score =  967 bits (2499), Expect = 0.0
 Identities = 555/1472 (37%), Positives = 860/1472 (58%), Gaps = 68/1472 (4%)

Query: 2723 YTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAA 2782
            Y    D+  +    + DTPE+L +K      S+  Y    E+ + KG    +     + A
Sbjct: 193  YKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIA 252

Query: 2783 KASRDIASEFKYKEGYRKQL----GHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEK 2838
            K + ++AS+ +Y + Y+K++    G  IGA  I               Q  + Y +++E+
Sbjct: 253  KRANELASDVRYHQQYQKEMRGMAGPAIGAEGILT--------RECADQYGQGYPEEYEE 304

Query: 2839 WKTKFSSPVDMLGVVL-AKKCQTLVSDVDYKNYLHQ------WTCLPDQSDVI--HARQA 2889
             + K S P  +      AKK   L SD+ Y+   ++      +  LP Q +++   A+  
Sbjct: 305  HRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSV 364

Query: 2890 YDLQSDNMYKSDLQ-WMRG-----------IGWVSIGSLDVEKCKRATEI---------- 2927
              L S+N YK + Q  MRG           +  + +GSL      +A             
Sbjct: 365  NKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPA 424

Query: 2928 --------------LSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKD 2973
                          L D  YRQ  D+ K++SVTD+ + V AK NA  ++   Y   ++K+
Sbjct: 425  TLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKN 484

Query: 2974 KTQIHIMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVIS 3033
            K    +  D P+++ A+ N   +SE  YK   E+ K KG++++ DA+ ++AAKAS ++ S
Sbjct: 485  KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELAS 544

Query: 3034 DYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDML 3093
            + KYK+ Y K  G  +G      D +++ S+ +AK+ S+ EYKK FE+ KT+F  P+DM+
Sbjct: 545  NIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMV 600

Query: 3094 GVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGW 3153
             +  AKK QTL SD+DY+  LHE+T LP+      A++AY LQS+  YK+DL W++G+GW
Sbjct: 601  NIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGW 660

Query: 3154 VPIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAW 3213
            +  GS+++ + K+A +++S+  YRQ  D+LKFTSVTDS +   AK +    +   Y    
Sbjct: 661  LTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGN 720

Query: 3214 DKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRD 3273
            ++   Q  I  D P  + AR N  N SE LY+ + E  K +G++LR D++  +AAKA RD
Sbjct: 721  EQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRD 780

Query: 3274 IASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPV 3333
            +AS+ KYKE Y +  G  IGA+ V  D ++  SL ++K+QS+ EYKK FE  K++    +
Sbjct: 781  LASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSL 840

Query: 3334 DMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKG 3393
            DM+ +V A+K Q L +DV YK   H +  LP    +  A+KAY LQSDN Y++D++WMKG
Sbjct: 841  DMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKG 900

Query: 3394 IGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYT 3453
            +GWV   SL V +AK+AGEL+S+  YRQ P+ LKFTSI DTPE V A+ +      RLY 
Sbjct: 901  MGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYR 960

Query: 3454 EAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKA 3513
            E  +N K       D PE++LAKLN +N S+  YK +  + +  GY LRLDA+P QAAKA
Sbjct: 961  EQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKA 1020

Query: 3514 SRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFS 3573
            S +I SDYKYKE + K  G  +G+R+++DD  +  S++   +QSD  YKK FE  K +F 
Sbjct: 1021 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1080

Query: 3574 SPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEW 3633
             P+DM  +V AKK Q L S+ DYKHPL ++T L +   +  A+KA+ LQS+ +Y+SDL +
Sbjct: 1081 LPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNF 1140

Query: 3634 LRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKH 3693
            +RG+  V  G++E+E  K+A E++S+ KYRQ     K+T +TDTP ++ AK +    ++ 
Sbjct: 1141 MRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNER 1200

Query: 3694 LYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKS 3753
            LY  A +  +    +    P+ + AK+N+AN+S   Y + W   + + Y L  +A+  ++
Sbjct: 1201 LYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQA 1260

Query: 3754 AKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKT 3813
            A+AS DIASD+ Y+  + K++G  IG QS+ DDP+I      G++QSE +Y++     + 
Sbjct: 1261 ARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQA 1320

Query: 3814 KFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKAD 3873
            +F  P+DM+ ++ AK  Q L +D DYR   H++T +P+   +  AKKA+ LQS+  YK+D
Sbjct: 1321 QFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSD 1380

Query: 3874 LEWLRGIGWMPQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENI 3933
            L  ++GIGW+   SP++   K A  +  ++ YR    ++K+T++VD+P++V AK++  + 
Sbjct: 1381 LIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHC 1440

Query: 3934 SIPKYREVWDKDKTSIH---IMPDTPEINLARANALNVSNKLYREGWDEMKAGC-DVRLD 3989
            +   YR     D  S+H   ++PD P+   AR NAL++S+K+YR  W++ +AG  D RLD
Sbjct: 1441 NERMYR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLD 1497

Query: 3990 AIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLD 4049
            AIP Q A+ASREIASD++YK    + +G  +G  +  DD +++  L   +LQ++ EY+ D
Sbjct: 1498 AIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKD 1557

Query: 4050 WAKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSD 4109
            +AK +++  S  D   +L +K SQ L SD+ YR  L Q TC P+Q  +  A+KA++LQSD
Sbjct: 1558 FAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSD 1617

Query: 4110 NVYKADLEWLRGIGWMPNDSVSVNHAKHAADI 4141
              YK+DL   RG+GW P  S  V  A+ AA++
Sbjct: 1618 VKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1649



 Score =  803 bits (2075), Expect = 0.0
 Identities = 475/1446 (32%), Positives = 793/1446 (54%), Gaps = 35/1446 (2%)

Query: 39   TSDYEQS--ETSKPALAQPA--LAQPASAKPVERRKVIRKKVDPSKFMTPYIAH----SQ 90
            T DYEQ   + S PA+  PA  +A+ A+    + R   + + +      P I      ++
Sbjct: 229  TEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTR 288

Query: 91   KMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHV 150
            +  D +    Y E++E+ +G+       TP  +  KK  +  S++KYR D +  K   H 
Sbjct: 289  ECADQYGQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHY 347

Query: 151  DE-KAKD---IEHAKKVSQQVSKVLYKQNWED-TKDKYLLPPDAPELVQAVKNTAMFSKK 205
                A+D   ++ A+ V++ VS+  YK+N+++  + +Y         + A+K  ++ S  
Sbjct: 348  HSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNV 407

Query: 206  LYTEDWEAD-KSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEF 264
             Y  D++ D     YP   +P   + A     L D  Y++ +   + +++ + D P I  
Sbjct: 408  AYKADYKHDIVDYNYPATLTPSY-QTAMKLVPLKDANYRQSI--DKLKYSSVTDTPQIVQ 464

Query: 265  AKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQIY 324
            AK    Q+S   Y+ DYE             ++  A+ NA   S  KY+E +E  K + +
Sbjct: 465  AKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGF 524

Query: 325  FMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSD 384
             M+ +       K +G  AS +KYKE+YEK KGKA    +  +++  L  L+ A    S+
Sbjct: 525  EMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA----MGTADSRLLHSLQIA-KMSSE 579

Query: 385  KLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHS 444
              YK+ +E++K +     +    +     Q  +SD  Y+       L  Y    ED    
Sbjct: 580  VEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKK-----LHEYTVLPEDMKTQ 634

Query: 445  HCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTQ 504
               K     S+  YKA+    +G G+  +      +A K      +  Y+   D+ KFT 
Sbjct: 635  WAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTS 694

Query: 505  VTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSDNLYKQD 564
            VTDS  +  A+ + +  S + YKA +E    +  I  D P F+Q + NA NLS+ LYK  
Sbjct: 695  VTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSS 754

Query: 565  WEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSL 624
            WE  KAK F++++D++  LAAKA     S+V YK+DYE+++GK+IG   +  D +M HSL
Sbjct: 755  WENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSL 814

Query: 625  KVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEARYKDLYVKDVLGHYVGS 684
            +++K QS+  YK+ +E TK++    C      +       ++    D+  K    H+   
Sbjct: 815  QMSKLQSELEYKKGFEDTKSQ----CHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 870

Query: 685  MEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKLDQCKDHTYKVHP 744
              D       K     SD  Y+A+ +  KG  +         +A K  +   +  Y+ HP
Sbjct: 871  PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 930

Query: 745  DKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLS 804
            D  KFT++ D+P ++QA+++  Q  D  Y+ + E  K      AD P+ +  ++NA N+S
Sbjct: 931  DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 990

Query: 805  DNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDD 864
            +  YK+ W K +   + +++DA+P  AAKA+ +  SD  YK+ +EK KG+M+G+ S+ DD
Sbjct: 991  ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1050

Query: 865  PKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILHSY 924
              + HS+     QSD  Y+K +E SK  +  PLDM  +  AKK+Q +AS+ DYKH L  Y
Sbjct: 1051 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1110

Query: 925  SYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASDILNEKKY 984
            +   + + +  AKKA+ LQS+  Y++D N +M+G   V  G+LE+E  K+AS++++E KY
Sbjct: 1111 TSLAEDLRLSCAKKAHKLQSENLYRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKY 1169

Query: 985  RQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNA 1044
            RQHP + K+T++ D P  + +K +    ++  YKA GE+  H+Y +   LP+FI+AK NA
Sbjct: 1170 RQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNA 1229

Query: 1045 YNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQS 1104
             N+S+  YK   ++L  +GY L  +A+P +AA+A+   ASD  Y+ D+ K +GK++G QS
Sbjct: 1230 ANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQS 1289

Query: 1105 LQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVSNVNYKHS 1164
            ++DDP++ H   + ++QS+ +Y++    ++++++ P DM ++V AK AQ + S+ +Y+  
Sbjct: 1290 VRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQ 1349

Query: 1165 LHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDALN 1224
             H +T LP+ + +  +K    +QS+  YK D    MKGIGW+ + S  +E  KKAG+ ++
Sbjct: 1350 YHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIGWLALRSPQMESAKKAGELIS 1408

Query: 1225 EKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQA 1284
            E KYR+ PD++KFT++VDSP +V AK +    ++ +Y++   +  H+YT+ PD P F +A
Sbjct: 1409 ETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRA 1468

Query: 1285 KCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKGKHV 1344
            + NA ++SD  Y+  W    A   +   DAIP   A+ASR IASD++YKEA+ + +G  +
Sbjct: 1469 RLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQI 1528

Query: 1345 GFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVATNVN 1404
            G+RS+ DDP++ H++NV +LQSD EYKK++  +++ +H+  D   +  AK +Q +A++V+
Sbjct: 1529 GYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVH 1588

Query: 1405 YKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVKKAG 1464
            Y+QPL   T  P+ + L H +  +Q+QSD  YK + N   +G+GW P GS +VE  ++A 
Sbjct: 1589 YRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLN-LTRGVGWTPPGSYKVEMARRAA 1647

Query: 1465 DALNER 1470
            +  N R
Sbjct: 1648 ELANAR 1653



 Score =  753 bits (1945), Expect = 0.0
 Identities = 483/1524 (31%), Positives = 809/1524 (53%), Gaps = 50/1524 (3%)

Query: 3363 LPDQNDI--IHARKAYDLQSDNLYKSDLEWMKGIGWVP-IDSLEVVRAKRAGELLSDTIY 3419
            LPD   +  + ARK+   +    Y  D E  +G G  P + +    RAK+A +L S   Y
Sbjct: 138  LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193

Query: 3420 RQRPETL--KFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAK 3476
            ++  +    +F+++ DTPE + +K  A   +   YTE ++  + K       TP   +AK
Sbjct: 194  KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAK 253

Query: 3477 LNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIG 3536
                  SD  Y    ++ +KE   +   AI  +    +R+ A   +Y +GY ++   H G
Sbjct: 254  RANELASDVRYH---QQYQKEMRGMAGPAIGAEGI-LTRECAD--QYGQGYPEEYEEHRG 307

Query: 3537 ARNIKD--DPKMMWSIHVAKIQSDREYKKEFEKWKTK---FSSPV-DMLGVVLAKKCQIL 3590
              +      P    +    ++ SD +Y+++F K K      S P  D L +  A+    L
Sbjct: 308  KGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKL 367

Query: 3591 VSDIDYK-----HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSD-----LEWLRGIGWV 3640
            VS+  YK     H    +  +      + A K   L S+  YK+D     +++       
Sbjct: 368  VSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLT 427

Query: 3641 PIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWD 3700
            P     ++ V      L D  YRQ  D+LK++ +TDTP+IV AK NA  +S   Y   ++
Sbjct: 428  PSYQTAMKLVP-----LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYE 482

Query: 3701 ADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDI 3760
             +K +  +  D P ++ AK+N+   S+  Y +GW+++K K ++++ DA+S+ +AKAS ++
Sbjct: 483  KNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGEL 542

Query: 3761 ASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVD 3820
            AS+ KYKE YEK KG  +G      D +++ ++   K+ SE EYKK F++ KT+F  P+D
Sbjct: 543  ASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMD 598

Query: 3821 MLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGI 3880
            M++I  AKK QTL +D+DYR  LHE+T +P+      AKKAY LQS+  YKADL W++G+
Sbjct: 599  MVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGV 658

Query: 3881 GWMPQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYRE 3940
            GW+ +GS  + + K A  +  +  YR  V  LK+TS+ D+ ++  AK + E  S   Y+ 
Sbjct: 659  GWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKA 718

Query: 3941 VWDKDKTSIHIMPDTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKAS 3999
              ++      I  D P    ARANA N+S KLY+  W+  KA G ++RLD++   AAKA 
Sbjct: 719  GNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAK 778

Query: 4000 REIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQS 4059
            R++AS+ KYK D+E+ +G  +G    + D+++  +L   KLQ+E EY+  +   K++   
Sbjct: 779  RDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHV 838

Query: 4060 PVDMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWL 4119
             +DM+ ++H++ +Q L +D+ Y+   H +T +P    V  AKKAY LQSDN Y+AD++W+
Sbjct: 839  SLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWM 898

Query: 4120 RGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIK 4179
            +G+GW+   S++V  AK A ++ SEKKYR   + L FT + D  + V A+ S     D  
Sbjct: 899  KGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRL 958

Query: 4180 YRKDWNATKSKYTLT-ETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHA 4238
            YR+     K  YT T + P +  A+  A  + +  YKE W + +  GY L  DA+PF  A
Sbjct: 959  YREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAA 1018

Query: 4239 HHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAK 4298
                ++ S+ KYK    K KG  +G  ++ DD  L    +A  +Q++  YK+ +  +KA+
Sbjct: 1019 KASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQ 1078

Query: 4299 INIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADL 4358
             ++P DM +++ AK+ QTL S+ DY++ L Q+    +   +  A+KA+ LQS+N+YR+DL
Sbjct: 1079 FHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL 1138

Query: 4359 EWLRGIGWIPLDSVDHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVN 4418
             ++RG+  +   +++     K  E++S+ KY+++   +   + +V D P ++ AK ++  
Sbjct: 1139 NFMRGVACVIPGTLEIEGRKKASELISESKYRQH--PHSFKYTAVTDTPNLLHAKFSNQI 1196

Query: 4419 QSDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYI 4478
             ++  YK     A+ +YT +   P    +K      S   YK +W   +A GY L    +
Sbjct: 1197 TNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEAL 1256

Query: 4479 PIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYE 4538
            P   A+ +  + S+  Y+  + K++G  +  + + + P + HC    +++S L YR+   
Sbjct: 1257 PFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGAT 1316

Query: 4539 DTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNV 4598
             ++A  H+P DM++ V AK  Q + SD +YR  +H++T+L E+  +   + A  + S+  
Sbjct: 1317 SSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELR 1376

Query: 4599 YKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAV 4658
            YK DL  +KGIG     +PQ+  AKK+ +L S+ +Y    K +   +  V D+P  V A 
Sbjct: 1377 YKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRK--KPDSIKFTTVVDSPDLVHAK 1434

Query: 4659 QSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYIL 4718
             S ++ +E  Y+    +   +YT + +  D+ R R      S  +Y+ +W++ +A SY  
Sbjct: 1435 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1494

Query: 4719 PSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLY 4778
                +    A+  + +AS  +Y+E + + + L    RSVDDDP     L VG+L  D  Y
Sbjct: 1495 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1554

Query: 4779 RSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQ 4838
            +  + K++ + H   D   ++ AK SQ+  S++ YR  L +  C P+     H +K    
Sbjct: 1555 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQL 1614

Query: 4839 ISDIVYKDDLNWLKGIGCYVWDTP 4862
             SD+ YK DLN  +G+G   W  P
Sbjct: 1615 QSDVKYKSDLNLTRGVG---WTPP 1635



 Score =  630 bits (1625), Expect = e-179
 Identities = 452/1581 (28%), Positives = 756/1581 (47%), Gaps = 234/1581 (14%)

Query: 3150 GIGWVP--IGSMDVVKCKRAAEILSDNI---YRQPPDKLKFTSVTDSLEQVLAKNNALNM 3204
            G  W P  +   ++V+   A + L +     Y QP  K  F ++     Q   K N L  
Sbjct: 130  GNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLAS 189

Query: 3205 NKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIP 3264
                Y    D+  ++   + DTPE++ ++      S+  Y +  E+ + +G         
Sbjct: 190  QVE-YKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248

Query: 3265 IVAAKASRDIASDYKYKEAYRKQL----GHHIGARAVHDDPKIMWSLHIAKVQSDREYKK 3320
               AK + ++ASD +Y + Y+K++    G  IGA  +               Q  + Y +
Sbjct: 249  YQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGI--------LTRECADQYGQGYPE 300

Query: 3321 DFEKYKTRYSSPVDMLGIVL-AKKCQTLVSDVDYKHPLHE------WICLPDQNDII--H 3371
            ++E+++ + S P  +      AKK   L SD+ Y+   ++      +  LP Q++++   
Sbjct: 301  EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ 360

Query: 3372 ARKAYDLQSDNLYKSDLE-----WMKGIGWVPIDSLEVVRAKRAGEL------------- 3413
            A+    L S+N YK + +       +G+G         + A + G L             
Sbjct: 361  AQSVNKLVSENKYKENYQNHMRGRYEGVGM----DRRTLHAMKVGSLASNVAYKADYKHD 416

Query: 3414 ----------------------LSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRL 3451
                                  L D  YRQ  + LK++S+TDTP+ V AK NA  ++   
Sbjct: 417  IVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVN 476

Query: 3452 YTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAA 3511
            Y   ++ +K    +  D P+++ AK N   +S+  YK   E++K +G++++LDA+ + AA
Sbjct: 477  YRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 536

Query: 3512 KASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTK 3571
            KAS ++AS+ KYKE Y K  G  +G      D +++ S+ +AK+ S+ EYKK FE+ KT+
Sbjct: 537  KASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR 592

Query: 3572 FSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDL 3631
            F  P+DM+ +  AKK Q L SD+DY+  LHE+T LP+      A+KAY LQS+  YK+DL
Sbjct: 593  FHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL 652

Query: 3632 EWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMS 3691
             W++G+GW+  GS+ +E+ K+AG+++S++ YRQ  D+LKFT +TD+ ++  AK +    S
Sbjct: 653  AWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQS 712

Query: 3692 KHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISI 3751
               Y    +       +  D P  L A++N+AN+S+KLY   W+  K K ++LR D+++ 
Sbjct: 713  GVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTF 772

Query: 3752 KSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKW 3811
             +AKA RD+AS+ KYKE YE+ +G  IGA+ ++ D ++  ++   K+QSE EYKK F+  
Sbjct: 773  LAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDT 832

Query: 3812 KTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYK 3871
            K++    +DM+ ++ A+K Q L TD+ Y+   H +T +P    +  AKKAY LQSD  Y+
Sbjct: 833  KSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYR 892

Query: 3872 ADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAE 3931
            AD++W++G+GW+  GS  V + K A  +  +  YR     LK+TSI DTPE+V A+ +  
Sbjct: 893  ADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYT 952

Query: 3932 NISIPKYREVWDKDKTSIHIMPDTPEINLARANALNVSNKLYREGWDEMK-AGCDVRLDA 3990
                  YRE  +  K       D PE+ LA+ NA+N+S   Y+E W +++  G  +RLDA
Sbjct: 953  QAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDA 1012

Query: 3991 IPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDW 4050
            +P QAAKAS EI SDYKYK   EK KG  +G+ +  DD  +  ++ A  LQ++  Y+  +
Sbjct: 1013 LPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGF 1072

Query: 4051 AKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDN 4110
               KA+   P+DM +++H+K +Q L S+ DY++ L Q+T + +   +  AKKA++LQS+N
Sbjct: 1073 EHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSEN 1132

Query: 4111 VYKADLEWLRGIGWM---------------------------------PNDSVSVNHAKH 4137
            +Y++DL ++RG+  +                                   D+ ++ HAK 
Sbjct: 1133 LYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKF 1192

Query: 4138 AADIFSEKKYRTKIETLN--FTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSK-YTLT 4194
            +  I +E+ Y+   E     +T      +++ AK +   L D +Y++ W   +++ Y LT
Sbjct: 1193 SNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLT 1252

Query: 4195 ETPL-LHTAQEAARILDQYLYKEGW--ERQKATG-------------------------- 4225
               L    A+ +  I   +LY+  +  ER K  G                          
Sbjct: 1253 IEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1312

Query: 4226 ---------YILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWF 4276
                     + LP D V  VHA +   + S+  Y+ ++ K    +  +P   +D K+ W 
Sbjct: 1313 RGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK----FTALP---EDLKMAWA 1365

Query: 4277 EHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNY---------- 4326
            + A  +Q+E  YK D    K    +      + +AK+   L+S+  YR            
Sbjct: 1366 KKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVV 1425

Query: 4327 ---------------------------LHQWMCHPDQNDVIQARKAYDLQSDNVYRADLE 4359
                                       LH++   PD  D  +AR      SD VYR   E
Sbjct: 1426 DSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWE 1485

Query: 4360 WLRGIGW-IPLDSVDHVRVTKNQEMMSQIKYKKNALENYP---NFRSVVDPPEIVLAKIN 4415
              R   +   LD++       ++E+ S  +YK+  L +      +RSV D P +      
Sbjct: 1486 QTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNV 1545

Query: 4416 SVNQSDVKYKETFNKAKGKYTFSPDTPHI------------------------------- 4444
               QSD +YK+ F K++ ++  S D P +                               
Sbjct: 1546 GRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGL 1605

Query: 4445 SHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNS-----ELKYKETY 4499
             H++   +L S + YK     T+  G+T    Y   +  + A+L N+     +  Y+   
Sbjct: 1606 RHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAE 1665

Query: 4500 EKQKGHYLAGKVIGEFPGVVH 4520
              + G + +G+V  +   ++H
Sbjct: 1666 AVEAGDHQSGEVNPDATEILH 1686



 Score =  436 bits (1122), Expect = e-121
 Identities = 387/1490 (25%), Positives = 667/1490 (44%), Gaps = 101/1490 (6%)

Query: 4165 YVTAKQSGEILDDIKYRKDWNATKSKY-TLTETPLLHTAQEAARILDQYLYKEGWERQKA 4223
            Y  AK++ ++   ++Y++  +   S++ T+ +TP L  ++  A++     Y E +E+Q+ 
Sbjct: 178  YQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRG 237

Query: 4224 TGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQ 4283
             G         +  A   N++ S+++Y  ++ K+     G     +   ++  E A Q  
Sbjct: 238  KGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEG--ILTRECADQYG 295

Query: 4284 NERLYKEDYHKTKAKINIPADMVSVLA-AKQGQTLVSDIDYRNYLHQ------WMCHPDQ 4336
                Y E+Y + + K + PA +      AK+   L SDI YR   ++      +   P Q
Sbjct: 296  QG--YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353

Query: 4337 NDVI--QARKAYDLQSDNVYRADLE-WLRG-IGWIPLDSVDHVRVTKNQEMMSQIKYKKN 4392
            ++++  QA+    L S+N Y+ + +  +RG    + +D    +   K   + S + YK +
Sbjct: 354  DNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRT-LHAMKVGSLASNVAYKAD 412

Query: 4393 ALE-----NYP-------------------NFR---------SVVDPPEIVLAKINSVNQ 4419
                    NYP                   N+R         SV D P+IV AKIN+   
Sbjct: 413  YKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQL 472

Query: 4420 SDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIP 4479
            S V Y+  + K K  YT   D P +  +K   KL+S + YK  WE TK  G+ +    + 
Sbjct: 473  SHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMS 532

Query: 4480 IVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPG-VVHCLDFQKMRSALNYRKHYE 4538
            ++ AK +  + S +KYKE YEK KG     K +G     ++H L   KM S + Y+K +E
Sbjct: 533  LLAAKASGELASNIKYKEEYEKTKG-----KAMGTADSRLLHSLQIAKMSSEVEYKKGFE 587

Query: 4539 DTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNV 4598
            ++K   H+P DM+N   AK+ Q + SDL+YR   H++T L E+      + A  + S+  
Sbjct: 588  ESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQ 647

Query: 4599 YKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAV 4658
            YK DL W+KG+G     +  +  AKK+  L S+  Y     E    +  VTD+     A 
Sbjct: 648  YKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDE--LKFTSVTDSSQMEHAK 705

Query: 4659 QSGINASEVKYKENYHQIKDKYTTVLETVDYDRTR-NLKNLYSSNLYKEAWDRVKATSYI 4717
            +S    S V YK    Q   +YT   +   + + R N  NL S  LYK +W+  KA  + 
Sbjct: 706  KSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANL-SEKLYKSSWENQKAKGFE 764

Query: 4718 LPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRL 4777
            L   +L+   AK ++ LAS +KY+E+YE+ +      + V  D   +  L++ KL  +  
Sbjct: 765  LRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELE 824

Query: 4778 YRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTD 4837
            Y+  +E  K + H+  DMV +V A+ +Q   +++ Y+   H +   P     +  +K   
Sbjct: 825  YKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYG 884

Query: 4838 QISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTP 4897
              SD  Y+ D+ W+KG+G     +  +  AK A +L  + KY+ H    +  +  + DTP
Sbjct: 885  LQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALK--FTSIKDTP 942

Query: 4898 VYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNL----YKTS 4953
              VQA  S  Q  D +Y  +   +++    P   T DL   L A KL + N+    YK S
Sbjct: 943  EMVQARISYTQAVDRLYR-EQGENIKHHYTP---TADLPEVLLA-KLNAMNISETRYKES 997

Query: 4954 LRTL-PTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPK----DVPFVH 5008
               L   GY+L  D   F+  K +  + S +KYKEA+E  K  G  LG +    D+   H
Sbjct: 998  WSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK--GQMLGSRSLEDDISLAH 1055

Query: 5009 VRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMI 5068
                 ++ S+  Y++ +   K + H   D   +   KK Q   S   YK           
Sbjct: 1056 SVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPL----PQYT 1111

Query: 5069 SLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTD 5128
            SL    ++   +    + S+  Y+ DL  ++G  C +  T ++   +   +L S   Y  
Sbjct: 1112 SLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ 1171

Query: 5129 KARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQ 5188
                   KY  V DTP     +      +E +Y+AAG+  +  +T     P+ +RAK   
Sbjct: 1172 HPHSF--KYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNA 1229

Query: 5189 KLQSQYLYVELATKERPH-HHAGNQTTALKHAKDVKDMVSEKKYKIQYEKMKDKY---TP 5244
               S   Y E     R   +    +    + A+   D+ S+  Y+  + K + K      
Sbjct: 1230 ANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQS 1289

Query: 5245 VPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKEN 5304
            V D P +   +R     S+L+Y+     ++ ++H   D + +V+ +    +   +    +
Sbjct: 1290 VRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAK----NAQALASDHD 1345

Query: 5305 YMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKT 5364
            Y +Q   + ++P+  +    +      S+++YK DL  +KGIG  A  +P    A+K   
Sbjct: 1346 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1405

Query: 5365 LYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEP 5424
            L S+ KY++  +  K  F  V DSP   H K +    NE+ YR+   +   +Y L+ D P
Sbjct: 1406 LISETKYRKKPDSIK--FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHP 1463

Query: 5425 RHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQI-SDILYKLEY--N 5481
                A+     +S   YR ++E+++             +T + +++I SD  YK  +  +
Sbjct: 1464 DFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRD 1523

Query: 5482 KAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKV 5541
            +    GY ++ D P + H   V    SD +YK+ + +++S      D   +  AK + ++
Sbjct: 1524 RGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQL 1583

Query: 5542 NTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKG 5591
             +++ Y++            P++     A K+   QSD +YK D    +G
Sbjct: 1584 ASDVHYRQPLPQPTC----DPEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1629



 Score =  350 bits (898), Expect = 3e-95
 Identities = 398/1633 (24%), Positives = 681/1633 (41%), Gaps = 179/1633 (10%)

Query: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY-VWDTPQILHAKKSYDLQSQLQYTAA 4637
            L +P ++R+  A++ L +  Y +D    +G G +    TP    AKK+  L SQ++Y   
Sbjct: 138  LPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196

Query: 4638 GKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYT-TVLETVDYDRTRNLK 4696
              E +  ++ V DTP  + +       S+V+Y E+Y Q + K +   + T  Y   +   
Sbjct: 197  HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRAN 256

Query: 4697 NLYSSNLYKEAWD---RVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTL 4753
             L S   Y + +    R  A   I     L+   A           Y EEYE+ +   + 
Sbjct: 257  ELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQ-----GYPEEYEEHRGKGSF 311

Query: 4754 PRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHI----VPDMVEMVTAKDSQKKVS 4809
            P  +      A+  +  +L  D  YR  + K K   H       D + +  A+   K VS
Sbjct: 312  PAMITPAYQNAK--KAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369

Query: 4810 EIDYRLRLHEWICHPDLQVND-----HVRKVTDQISDIVYKDDLNWLKGIGCYVWD---T 4861
            E  Y+      +      V       H  KV    S++ YK D  +   I  Y +    T
Sbjct: 370  ENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKAD--YKHDIVDYNYPATLT 427

Query: 4862 PEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHS 4921
            P    A     L+D   Y+  + K +  Y  VTDTP  VQA  + +QLS   Y  DY  +
Sbjct: 428  PSYQTAMKLVPLKD-ANYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKN 484

Query: 4922 VRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSL-RTLPTGYRLPGDTPHFKHIKDTRYMS 4980
                  P      L +A    KL S   YK    +T   G+ +  D       K +  ++
Sbjct: 485  KLNYTLPQD-VPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELA 543

Query: 4981 SYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPE 5040
            S  KYKE YE TK  G  +G  D   +H  ++  ++SE  Y++ + + K + H   D   
Sbjct: 544  SNIKYKEEYEKTK--GKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVN 601

Query: 5041 IRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKG 5100
            IR  KK Q   S+L Y+    K+  + + LP   +    +    + S+++YK DL  +KG
Sbjct: 602  IRHAKKAQTLASDLDYRK---KLHEYTV-LPEDMKTQWAKKAYGLQSELQYKADLAWMKG 657

Query: 5101 FGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELV 5160
             G     + ++ +++   +L S   Y  +  ++  K+  V D+ +    ++ +   S + 
Sbjct: 658  VGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL--KFTSVTDSSQMEHAKKSQELQSGVA 715

Query: 5161 YRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQTTALKHA 5219
            Y+A  ++    +T   D P  L+A+      S+ LY      ++         +     A
Sbjct: 716  YKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAA 775

Query: 5220 KDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNA---SDLRYKETFQKTKGK 5276
            K  +D+ SE KYK  YE+ + K     D     +   +   +   S+L YK+ F+ TK +
Sbjct: 776  KAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQ 835

Query: 5277 YHTVKDALDIVYHRKVTDDISKIKYK--ENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDV 5334
             H   D + +V+ RK     + + YK  E++ + L      P   +    +      SD 
Sbjct: 836  CHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL------PTDMKVEWAKKAYGLQSDN 889

Query: 5335 KYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPIN-RH 5393
            +Y+ D+ W+KG+G                                    +VA   +N   
Sbjct: 890  QYRADVKWMKGMG------------------------------------WVATGSLNVEQ 913

Query: 5394 FKYATQLMNEKKYRADYEQRKD--KYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK 5451
             K A +L++EKKYR    Q  D  K+  + D P  + A+ +  Q     YR+  E  K  
Sbjct: 914  AKKAGELISEKKYR----QHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH 969

Query: 5452 FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLK 5511
            +T   D PE L        IS+  YK  ++K +  GY    D       +   + +SD K
Sbjct: 970  YTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYK 1029

Query: 5512 YKEVYQRNKSNC----TIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDF 5567
            YKE +++ K       ++E D + +  +  A  + ++++YKK +E +KA +    D    
Sbjct: 1030 YKEAFEKMKGQMLGSRSLEDD-ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAAL 1088

Query: 5568 LQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGT 5627
            + A K+    S+ +YK           S+ +D     A +   ++S+  Y+      RG 
Sbjct: 1089 VHAKKAQTLASNQDYKHPLPQYT----SLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1144

Query: 5628 CHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT 5687
               +P T +I   K  S L+SE+KY+ H         YT + +T + +H K   +  ++ 
Sbjct: 1145 ACVIPGTLEIEGRKKASELISESKYRQHPHSF----KYTAVTDTPNLLHAKFSNQITNER 1200

Query: 5688 NYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKK 5747
             YK                                  A  +DA+    YT     P+  +
Sbjct: 1201 LYK----------------------------------AAGEDARHE--YTMTLGLPEFIR 1224

Query: 5748 ATQAAKQASEVEYRAKHRKEGSHGLSM-LGRPDIEMAKKAAKLSSQVKYRENFDKEKGKT 5806
            A   A   S+  Y+   R   + G  + +     + A+ +  ++S   YR +F KE+GK 
Sbjct: 1225 AKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKL 1284

Query: 5807 -PKYNPKDSQLYKVMKDANNLASEVKYK----ADLKKLHKPVTDMKESLIMNHVLNTSQL 5861
                + +D    +  +    L SE++Y+    +   + H P+    + + + H  N   L
Sbjct: 1285 IGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPM----DMVHLVHAKNAQAL 1340

Query: 5862 ASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPT 5921
            AS + Y+ +Y K    +  +P++L+    K+A  LQS ++YK      +G   L   +P 
Sbjct: 1341 ASDHDYRTQYHK----FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1396

Query: 5922 YITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEES 5981
              +AK++ ++ S  +YRK   +SIK    T +  +P L+H K +    +E+ YR    ES
Sbjct: 1397 MESAKKAGELISETKYRKK-PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYRSGDAES 1452

Query: 5982 IRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNAT 6041
            +     T + D PD  RA+     L++K Y+   E + +    +   +  P F  AR + 
Sbjct: 1453 LHR--YTLIPDHPDFTRARLNALHLSDKVYRNSWE-QTRAGSYDFRLDAIP-FQTARASR 1508

Query: 6042 DIASQIKYKQSAEMEKA---NFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETV 6098
            +IAS  +YK++   ++     + SV D P + H   V  L S  +YK+D  KS S + + 
Sbjct: 1509 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1568

Query: 6099 LDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNF---SSVLYK 6155
             D P + + + +Q+  S + Y+  L             PE L ++  QK     S V YK
Sbjct: 1569 TDQPGLLQAKRSQQLASDVHYRQPLPQP-------TCDPEQLGLRHAQKAHQLQSDVKYK 1621

Query: 6156 EDVSPGTAIGKTP 6168
             D++    +G TP
Sbjct: 1622 SDLNLTRGVGWTP 1634



 Score =  321 bits (822), Expect = 2e-86
 Identities = 402/1653 (24%), Positives = 692/1653 (41%), Gaps = 149/1653 (9%)

Query: 4407 PEIVLAKINSVNQSDVKYKETFNKAKGKYTF-SPDTPHISHSKDMGKLYSTILYK-GAWE 4464
            PEIV   + +      +Y E + + +GK +F +  TP    +K   +L S + YK G  E
Sbjct: 141  PEIV-RMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199

Query: 4465 GTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVH---- 4520
                +   +D     ++ +K    + S+++Y E YE+Q+G        G FP ++     
Sbjct: 200  RISRFSTVVDTP--ELLRSKAGAQLQSDVRYTEDYEQQRGK-------GSFPAMITPAYQ 250

Query: 4521 -CLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRC-----QYILSDLEYRHYFHQ 4574
                  ++ S + Y + Y+     +  P      +L + C     Q    + E       
Sbjct: 251  IAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGS 310

Query: 4575 WTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY----VWDTPQILHAKKSYDLQS 4630
            + +++  P     + A E+ SD  Y+ D N +KG   Y      D   +  A+    L S
Sbjct: 311  FPAMIT-PAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369

Query: 4631 QLQYTAAGKENLQN-----YNLVTDTPLYVTAVQSGINASEVKYKENY-HQIKDKYTTVL 4684
            + +Y    KEN QN     Y  V      + A++ G  AS V YK +Y H I D      
Sbjct: 370  ENKY----KENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPAT 425

Query: 4685 ETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEY 4744
             T  Y     L  L  +N Y+++ D++K +S    + T  +  AK      SH+ YR +Y
Sbjct: 426  LTPSYQTAMKLVPLKDAN-YRQSIDKLKYSSV---TDTPQIVQAKINAQQLSHVNYRADY 481

Query: 4745 EKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMK-IHIVPDMVEMVTAKD 4803
            EK K  YTLP+ V   P   +     KL  +  Y+  +EK K K   +  D + ++ AK 
Sbjct: 482  EKNKLNYTLPQDV---PQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKA 538

Query: 4804 SQKKVSEIDYRLRLHEWICHPDLQVND----HVRKVTDQISDIVYKDDLNWLKGIGCYVW 4859
            S +  S I Y+   +E      +   D    H  ++    S++ YK      K       
Sbjct: 539  SGELASNIKYKEE-YEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPM 597

Query: 4860 DTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYV 4919
            D   I HAK A  L  D+ Y+    K  ++Y ++ +      A K+    S+  Y  D  
Sbjct: 598  DMVNIRHAKKAQTLASDLDYR----KKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLA 653

Query: 4920 HSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYM 4979
              ++G    T  +++L++A  A +L S   Y+  +  L   +    D+   +H K ++ +
Sbjct: 654  W-MKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELK--FTSVTDSSQMEHAKKSQEL 710

Query: 4980 SSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDK-IHTTPDT 5038
             S   YK   E +  + YT+   +  F+  R      SE+LY+  +   K K      D+
Sbjct: 711  QSGVAYKAGNEQS-VHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDS 769

Query: 5039 PEIRQVKKTQEAVSELIYKSDFFKMQGHMIS---LPYTPQVIHCRYVGDITSDIKYKEDL 5095
                  K  ++  SE+ YK D+ + +G +I    +    Q+ H   +  + S+++YK+  
Sbjct: 770  LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGF 829

Query: 5096 QVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTH 5155
            +  K   C +  + DMV   H RK  + +L TD   K  + +                  
Sbjct: 830  EDTKS-QCHV--SLDMVHLVHARK--AQHLATDVGYKTAEHH------------------ 866

Query: 5156 LSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTA 5215
                            FT++P    +  AK+   LQS   Y       +        +  
Sbjct: 867  ----------------FTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLN 910

Query: 5216 LKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKG 5275
            ++ AK   +++SEKKY+   + +K  +T + DTP +++A+ +Y  A D  Y+E  +  K 
Sbjct: 911  VEQAKKAGELISEKKYRQHPDALK--FTSIKDTPEMVQARISYTQAVDRLYREQGENIKH 968

Query: 5276 KYHTVKDALDIVYHRKVTDDISKIKYKENYMS-QLGIWRSIPDRPEHFHHRAVTDTVSDV 5334
             Y    D  +++  +    +IS+ +YKE++   + G ++   D       +A  + +SD 
Sbjct: 969  HYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDY 1028

Query: 5335 KYKEDLTWLKG--IGCYAYDTPDFTLAEK--NKTLYSKYKYKEVFERTKSDFKYVADSPI 5390
            KYKE    +KG  +G  + +  D +LA      +L S   YK+ FE +K+ F    D   
Sbjct: 1029 KYKEAFEKMKGQMLGSRSLED-DISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAA 1087

Query: 5391 NRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKD 5450
              H K A  L + +    DY+    +Y  + ++ R   AK A    S+  YR +    + 
Sbjct: 1088 LVHAKKAQTLASNQ----DYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRG 1143

Query: 5451 KFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDL 5510
                I  T E     K ++ IS+  Y+   +  K   YT + DTP LLH +      ++ 
Sbjct: 1144 VACVIPGTLEIEGRKKASELISESKYRQHPHSFK---YTAVTDTPNLLHAKFSNQITNER 1200

Query: 5511 KYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAH-WKWTPDRPDFLQ 5569
             YK   +  +   T+         AK      ++  YK+ +   +A  +K T +   F  
Sbjct: 1201 LYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQA 1260

Query: 5570 AAKSSLQQSDFEYKLDREFLKGCKL---SVTDDKNTVLALRNTLIESDLKYKEKHVKERG 5626
            A  S    SDF Y+ D    +G  +   SV DD       R   ++S+L+Y+      + 
Sbjct: 1261 ARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQA 1320

Query: 5627 TCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSD 5686
              H   D   ++ AK    L S++ Y+    K      +T LPE       K+     S+
Sbjct: 1321 QFHLPMDMVHLVHAKNAQALASDHDYRTQYHK------FTALPEDLKMAWAKKAHALQSE 1374

Query: 5687 TNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIK 5746
              YK   +  KG     + L  P+++ A +  +  S+  YRK   +++ +TTV D PD+ 
Sbjct: 1375 LRYKSDLIGMKGIG--WLALRSPQMESAKKAGELISETKYRKKP-DSIKFTTVVDSPDLV 1431

Query: 5747 KATQAAKQASEVEYRAKHRKEGSHGLSML-GRPDIEMAKKAAKLSSQVKYRENFDKEKGK 5805
             A  +    +E  YR+    E  H  +++   PD   A+  A   S   YR ++++ +  
Sbjct: 1432 HAKNSYMHCNERMYRSGDA-ESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAG 1490

Query: 5806 TPKYNPKDSQLYKVMKDANNLASEVKYKADLKK---LHKPVTDMKESLIMNHVLNTSQLA 5862
            +  +   D+  ++  + +  +AS+ +YK    +   L      + +   M H LN  +L 
Sbjct: 1491 SYDFR-LDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQ 1549

Query: 5863 SSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTY 5922
            S  +YKK + KS+  +H+  D    L  K + +L S V Y++       +P  D E    
Sbjct: 1550 SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLP----QPTCDPEQLGL 1605

Query: 5923 ITAKESQQMQSGKEYRKDYEESIKGRNLT-GLEVT-PALLHVKYATKIASEKEYR-KDLE 5979
              A+++ Q+QS  +Y+ D        NLT G+  T P    V+ A + A     R   L+
Sbjct: 1606 RHAQKAHQLQSDVKYKSDL-------NLTRGVGWTPPGSYKVEMARRAAELANARGLGLQ 1658

Query: 5980 ESIRGKGLTEMEDTPDMLRAKNATQILNEKEYK 6012
             + RG    E  D        +AT+IL+ K+ K
Sbjct: 1659 GAYRGAEAVEAGDHQSGEVNPDATEILHVKKKK 1691



 Score =  318 bits (814), Expect = 1e-85
 Identities = 387/1603 (24%), Positives = 669/1603 (41%), Gaps = 221/1603 (13%)

Query: 5109 PDMVRSRHLRKLWSNYLYTDKARKMRDKYKV-VLDTPEYRKVQELKTHLSELVYRAAGKK 5167
            P++VR    RK      YT+   + R K     + TP Y++ ++     S++ Y+    +
Sbjct: 141  PEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199

Query: 5168 QKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPH-HHAGNQTTALKHAKDVKDMV 5226
            + S F++V DTP+LLR+K G +LQS   Y E   ++R         T A + AK   ++ 
Sbjct: 200  RISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELA 259

Query: 5227 SEKKYKIQYEK-------------------MKDKYT----------------PVPDTPIL 5251
            S+ +Y  QY+K                     D+Y                 P   TP  
Sbjct: 260  SDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAY 319

Query: 5252 IRAKRAYWNASDLRYKETFQKTKGK--YHTV--KDALDIVYHRKVTDDISKIKYKENYMS 5307
              AK+A+  ASD++Y++ F K KG   YH++  +D L +   + V   +S+ KYKENY +
Sbjct: 320  QNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQN 379

Query: 5308 QL-GIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYD---TPDFTLAEKNK 5363
             + G +  +       H   V    S+V YK D  +   I  Y Y    TP +  A K  
Sbjct: 380  HMRGRYEGVGMDRRTLHAMKVGSLASNVAYKAD--YKHDIVDYNYPATLTPSYQTAMKLV 437

Query: 5364 TLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDE 5423
             L     Y++  ++ K  +  V D+P     K   Q ++   YRADYE+ K  Y L  D 
Sbjct: 438  PLKDA-NYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDV 494

Query: 5424 PRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNK 5482
            P+ + AKT     S++KY++ +EK+K K F   +D    L      +  S+I YK EY K
Sbjct: 495  PQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEK 554

Query: 5483 AKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVN 5542
             K +   T      LLH  ++    S+++YK+ ++ +K+   +  D V+I+ AK A  + 
Sbjct: 555  TKGKAMGTADSR--LLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 612

Query: 5543 TNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCK--------- 5593
            ++LDY+K+       +   P+      A K+   QS+ +YK D  ++KG           
Sbjct: 613  SDLDYRKKLH----EYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNL 668

Query: 5594 ------------------------LSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCH 5629
                                     SVTD      A ++  ++S + YK  + +      
Sbjct: 669  EQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYT 728

Query: 5630 AVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNY 5689
               D P  L A+  +  +SE  YK   +   A+G    L ++   +  K      S+  Y
Sbjct: 729  ISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRL-DSLTFLAAKAKRDLASEVKY 787

Query: 5690 KKKFVKEKGKSNYSIMLE-PPEVKHAMEVAKKQSDVAYRK---DAKENLH---------- 5735
            K+ + + +GK   +  ++   ++ H+++++K QS++ Y+K   D K   H          
Sbjct: 788  KEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVH 847

Query: 5736 -------------------YTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLG 5776
                               +T +     ++ A +A    S+ +YRA  +     G    G
Sbjct: 848  ARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATG 907

Query: 5777 RPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKA-- 5834
              ++E AKKA +L S+ KYR++ D  K  + K  P+  Q     + +   A +  Y+   
Sbjct: 908  SLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQA----RISYTQAVDRLYREQG 963

Query: 5835 -DLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSK-GHYHTIPDNLEQLHLKE 5892
             ++K  + P  D+ E L+    LN   ++ + +YK+ + K + G Y    D L     K 
Sbjct: 964  ENIKHHYTPTADLPEVLLAK--LNAMNISET-RYKESWSKLRDGGYKLRLDALPFQAAKA 1020

Query: 5893 ATELQSIVKYKEKYEKERGKPMLDFETPTYITAKES---QQMQSGKEYRKDYEESIKGRN 5949
            + E+ S  KYKE +EK +G+ +        I+   S     +QS   Y+K +E S K + 
Sbjct: 1021 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS-KAQF 1079

Query: 5950 LTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEK 6009
               L++  AL+H K A  +AS ++Y+  L +       T + +   +  AK A ++ +E 
Sbjct: 1080 HLPLDMA-ALVHAKKAQTLASNQDYKHPLPQ------YTSLAEDLRLSCAKKAHKLQSEN 1132

Query: 6010 EYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEI 6069
             Y+ DL      RG+  +   T +    + A+++ S+ KY+Q     K  +T+V DTP +
Sbjct: 1133 LYRSDLNFM---RGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK--YTAVTDTPNL 1187

Query: 6070 IHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKG- 6128
            +HA+    +++++ YK   E +   Y   L  PE  R + N  N S  +Y+   +N +  
Sbjct: 1188 LHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQ 1247

Query: 6129 --KITVVQDTPEILRVKENQKNFSSVLYKEDV--SPGTAIGKTPEMMRVKQTQDHISSVK 6184
              K+T+  +       + +    S  LY+ D     G  IG  P+ +R            
Sbjct: 1248 GYKLTI--EALPFQAARASGDIASDFLYRHDFVKERGKLIG--PQSVR------------ 1291

Query: 6185 YKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTP----EIERVKRNQE 6240
                        D P ++  +   +  S + Y+    +       P     +   K  Q 
Sbjct: 1292 ------------DDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQA 1339

Query: 6241 NFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENM----GKGTPLAVTPEMER 6296
              S   Y+    K    P   +M   K+     S + YK ++    G G     +P+ME 
Sbjct: 1340 LASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMES 1399

Query: 6297 VKHNQENISSVLYKENVGKATATPV--TPEMQRVKRNQENISSVLYK----ENLGKATPT 6350
             K   E IS   Y++       T V  +P++   K +  + +  +Y+    E+L + T  
Sbjct: 1400 AKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLI 1459

Query: 6351 PFTPEMERVKRNQENFSSVLYKENMRKATPTPVTPEMER-----AKRNQENISSVLYSDS 6405
            P  P+  R + N  + S  +Y+ +  +         ++      A+ ++E  S   Y ++
Sbjct: 1460 PDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEA 1519

Query: 6406 FRKQIQGKAAY--VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKK 6463
            F +    +  Y  V D P M+      R  S  +Y +DF K +  F      P   + K+
Sbjct: 1520 FLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKR 1579

Query: 6464 NMQDFSDINYRGIQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSL 6523
            + Q  SD++YR        + Q   D +Q    GLR  +       D     D   +R +
Sbjct: 1580 SQQLASDVHYR------QPLPQPTCDPEQ---LGLRHAQKAHQLQSDVKYKSDLNLTRGV 1630

Query: 6524 -----HMINVQAQRRSREQSRSASALSISGGEEKSEHSEAPDH 6561
                     V+  RR+ E + +A  L + G    +E  EA DH
Sbjct: 1631 GWTPPGSYKVEMARRAAELA-NARGLGLQGAYRGAEAVEAGDH 1672



 Score =  315 bits (808), Expect = 7e-85
 Identities = 373/1541 (24%), Positives = 651/1541 (42%), Gaps = 193/1541 (12%)

Query: 4844 YKDDLNWLKGIGCY-VWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQA 4902
            Y +D    +G G +    TP    AK A  L   ++YK    +  + +  V DTP  +++
Sbjct: 157  YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRS 216

Query: 4903 VKSGKQL-SDAVYHYDYVHSVRGKVA-PTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTG 4960
             K+G QL SD  Y  DY    RGK + P   T     A  A +L S   Y    +    G
Sbjct: 217  -KAGAQLQSDVRYTEDYEQQ-RGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRG 274

Query: 4961 YRLPGDTPHFKHIKDTRYMSSYFK-YKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSER 5019
              + G     + I        Y + Y E YE  +  G         + + ++ + + S+ 
Sbjct: 275  --MAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDI 332

Query: 5020 LYRELYHKLKDKIH----TTPDTPEIRQVKKTQEAVSELIYKSDFFK-MQGHMISLPYTP 5074
             YR+ ++K+K   H       D   ++Q +   + VSE  YK ++   M+G    +    
Sbjct: 333  KYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDR 392

Query: 5075 QVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMR 5134
            + +H   VG + S++ YK D +             D+V   +   L  +Y    K   ++
Sbjct: 393  RTLHAMKVGSLASNVAYKADYK------------HDIVDYNYPATLTPSYQTAMKLVPLK 440

Query: 5135 D----------KYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRA 5184
            D          KY  V DTP+  + +     LS + YRA  +K K  +T   D P L++A
Sbjct: 441  DANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKA 500

Query: 5185 KRGQKLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYT 5243
            K   KL S+  Y E   K +           +L  AK   ++ S  KYK +YEK K K  
Sbjct: 501  KTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAM 560

Query: 5244 PVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKE 5303
               D+ +L   + A  + S++ YK+ F+++K ++H   D ++I + +K     S + Y++
Sbjct: 561  GTADSRLLHSLQIAKMS-SEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRK 619

Query: 5304 NYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNK 5363
                +L  +  +P+  +    +      S+++YK DL W+KG+G     + +   A+K  
Sbjct: 620  ----KLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAG 675

Query: 5364 TLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDE 5423
             L S+  Y++  +  K  F  V DS    H K + +L +   Y+A  EQ   +Y +  DE
Sbjct: 676  QLVSEKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 733

Query: 5424 PRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNK 5482
            P  L A+     +S+  Y+ ++E  K K F   +D+   L         S++ YK +Y +
Sbjct: 734  PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYER 793

Query: 5483 AKPR--GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYK 5540
            ++ +  G   +     + H  ++    S+L+YK+ ++  KS C +  D VH+  A+ A  
Sbjct: 794  SRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQH 853

Query: 5541 VNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDK 5600
            + T++ YK      + H+   P       A K+   QSD +Y+ D +++KG     T   
Sbjct: 854  LATDVGYKTA----EHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSL 909

Query: 5601 NTVLALRNTLIESDLKYKE----------------------------KHVKERGTC---H 5629
            N   A +   + S+ KY++                            +  +E+G     H
Sbjct: 910  NVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH 969

Query: 5630 AVP--DTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT 5687
              P  D P++LLAK  +  +SE +YK+   K L  G Y    +       K   + +SD 
Sbjct: 970  YTPTADLPEVLLAKLNAMNISETRYKESWSK-LRDGGYKLRLDALPFQAAKASGEIISDY 1028

Query: 5688 NYKKKFVKEKGKSNYSIMLEPP-EVKHAMEVAKKQSDVAYRKD---AKENLH-------- 5735
             YK+ F K KG+   S  LE    + H++     QSDV Y+K    +K   H        
Sbjct: 1029 KYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAAL 1088

Query: 5736 ---------------------YTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSM 5774
                                 YT++A+   +  A +A K  SE  YR+           +
Sbjct: 1089 VHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVI 1148

Query: 5775 LGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKA 5834
             G  +IE  KKA++L S+ KYR++    K       P         K +N + +E  YKA
Sbjct: 1149 PGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHA----KFSNQITNERLYKA 1204

Query: 5835 ---DLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYE--KSKGHYHTIPDNLEQLH 5889
               D +  +     + E   +    N + L+ + +YK+ +   +++G+  TI + L    
Sbjct: 1205 AGEDARHEYTMTLGLPE--FIRAKTNAANLSDA-RYKESWRNLRAQGYKLTI-EALPFQA 1260

Query: 5890 LKEATELQSIVKYKEKYEKERGK---PMLDFETPTYITAKESQQMQSGKEYRKDYEESIK 5946
             + + ++ S   Y+  + KERGK   P    + P     +   Q+QS  +YR+    S  
Sbjct: 1261 ARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQA 1320

Query: 5947 GRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQIL 6006
              +L    V   L+H K A  +AS+ +YR    +       T + +   M  AK A  + 
Sbjct: 1321 QFHLPMDMVH--LVHAKNAQALASDHDYRTQYHK------FTALPEDLKMAWAKKAHALQ 1372

Query: 6007 NEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDT 6066
            +E  YK DL   +  +G+  +A  +P    A+ A ++ S+ KY++  +  K  FT+VVD+
Sbjct: 1373 SELRYKSDL---IGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIK--FTTVVDS 1427

Query: 6067 PEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNS 6126
            P+++HA+      +++ Y+    +S+  Y  + D P+  R R N  + S   Y+   + +
Sbjct: 1428 PDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQT 1487

Query: 6127 KG----------KITVVQDTPEI---LRVKE-------------------NQKNFSSV-- 6152
            +                + + EI    R KE                     K+F +V  
Sbjct: 1488 RAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGR 1547

Query: 6153 -----LYKEDVSPGTAIGKT----PEMMRVKQTQDHISSVKYKEAIGQGTPIPDLPEVKR 6203
                  YK+D +   +   +    P +++ K++Q   S V Y++ + Q T  P+   ++ 
Sbjct: 1548 LQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRH 1607

Query: 6204 VKETQKHISSVMYKENL----GTGIPTTVTPEIERVKRNQE 6240
             ++  +  S V YK +L    G G     + ++E  +R  E
Sbjct: 1608 AQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAE 1648


>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
          Length = 1014

 Score =  631 bits (1628), Expect = e-180
 Identities = 352/792 (44%), Positives = 499/792 (63%), Gaps = 17/792 (2%)

Query: 5596 VTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDH 5655
            V +D +  LA + T + SD++YKE+  K +  C  V D+P +   K +   +SE KYK  
Sbjct: 33   VIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGT 92

Query: 5656 VKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAM 5715
            +K  L+   Y  +P T D+V   EVT+  S+  YK+K    KG S+Y+ M EPPEVKHAM
Sbjct: 93   IKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAM 152

Query: 5716 EVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSML 5775
            EV K QS+++YRKD ++   Y+   DRPDIK ATQ +K  S  EY+ K +   +   +++
Sbjct: 153  EVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYK-KGQGIMNKEPAVI 211

Query: 5776 GRPDIEMAKKAAKLSSQVKYRENFDKE-KGKTPKYNPKDSQLYKVMKDANNLASEVKYKA 5834
            GRPD E A +A+KLSSQ+KY+E FD E K K   YNP +S  ++  + A  LAS VKYK 
Sbjct: 212  GRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKK 271

Query: 5835 DLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEAT 5894
            D++ +H PV+D+   L ++HVL  S++ S  +YKK +E++KG YH   D +E LH K   
Sbjct: 272  DIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNA 331

Query: 5895 ELQSIVKYKEKYEKERGKPMLDF-ETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGL 5953
             LQS VKYKE+YEK +GKPML+F ETP+Y  +KE+Q+MQS K Y++D+E+ IKGR+   L
Sbjct: 332  VLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDL 391

Query: 5954 EVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKR 6013
            + TP  LHVKY T +  EKEY+KDLE  I+GKG+    +  D+ RAK A+++ +EKEYK+
Sbjct: 392  DKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKK 451

Query: 6014 DLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEME-KANFTSV-VDTPEIIH 6071
            DLE  +KG+G+ A   +T +   A+ A +IAS+  YK+  E E K     V  DT ++  
Sbjct: 452  DLESIIKGKGMQA-GTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQR 510

Query: 6072 AQQVKNLSSQKKYKEDAEKSMSY--YETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGK 6129
            A++   ++SQK+YK+D E  +     +  +D P+I R +   + +S  +Y+ + +     
Sbjct: 511  AKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSN 570

Query: 6130 ITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEMMRVKQTQDHISSVKYKEAI 6189
             + + DTPEI R+K  Q+N S+V YK++V  GTA+  +PE+ RVK+ Q +ISSVKYKE I
Sbjct: 571  YSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEI 630

Query: 6190 GQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTPEIERVKRNQENFSSVLYKE 6249
               T I D PE+KRVKE QK+IS++ YKE      P ++TPEIERV+RNQE  S+V YK 
Sbjct: 631  KHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKG 690

Query: 6250 NLGKGIPTPITPEMERVKRNQENFSSVLYKENMGKGTPLAVTPEMERVKHNQENISSVLY 6309
             L +G      PE++R K NQ+N S+V Y+  +G+ T L+VTPEMERVK NQENISSV Y
Sbjct: 691  ELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKY 750

Query: 6310 ----KENVGKATATPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEM-----ERVK 6360
                K+  G+ +    TP M+ VK  Q +IS V Y E+  K     FTP +     ERV+
Sbjct: 751  TQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVR 810

Query: 6361 RNQENFSSVLYK 6372
            +N +  S   YK
Sbjct: 811  KNTQVVSDAAYK 822



 Score =  561 bits (1447), Expect = e-159
 Identities = 373/1057 (35%), Positives = 575/1057 (54%), Gaps = 110/1057 (10%)

Query: 5639 LAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKG 5698
            LA+  + L+S+ +YK+  KK   + ++ T  ++    HVK +   +S+  YK     +  
Sbjct: 41   LARKCTELISDIRYKEEFKKSKDKCTFVT--DSPMLNHVKNIGAFISEAKYKGTIKADLS 98

Query: 5699 KSNYSIMLEPPEVKHAMEVAKKQSDVAYRKD---AKENLHYTTVADRPDIKKATQAAKQA 5755
             S Y  M    +   A EV + QS+VAY++    AK    Y  + + P++K A +  K  
Sbjct: 99   NSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQ 158

Query: 5756 SEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQ 5815
            S + YR   +   ++    L RPDI+MA + +K+ S  +Y++                  
Sbjct: 159  SNISYRKDVQDTHTYSAE-LDRPDIKMATQISKIISNAEYKKG----------------- 200

Query: 5816 LYKVMKDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYE--- 5872
                 +   N    V  + D +                H +  S+L+S  +YK+K++   
Sbjct: 201  -----QGIMNKEPAVIGRPDFE----------------HAVEASKLSSQIKYKEKFDNEM 239

Query: 5873 KSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYIT-AKESQQM 5931
            K K H++   ++      + A  L S VKYK+  +     P+ D     ++    ++ +M
Sbjct: 240  KDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHD-PVSDLPNLLFLDHVLKASKM 298

Query: 5932 QSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEME 5991
             SG+EY+K +EE+ KG      +    L H   A  + S+ +Y+++ E++ +GK + E  
Sbjct: 299  LSGREYKKLFEEN-KGMYHFDADAVEHLHHKGNAV-LQSQVKYKEEYEKN-KGKPMLEFV 355

Query: 5992 DTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQ 6051
            +TP    +K A ++ +EK YK D E E+KGR  +   ++TP+F+  +  T++  + +YK+
Sbjct: 356  ETPSYQASKEAQKMQSEKVYKEDFEKEIKGRS-SLDLDKTPEFLHVKYITNLLREKEYKK 414

Query: 6052 SAEMEKANFTSVVDTP--EIIHAQQVKNLSSQKKYKEDAEKSMSY--YETVLDTPEIQRV 6107
              E E       +++   +I  A++   ++S+K+YK+D E  +     +   DT E+Q  
Sbjct: 415  DLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHA 474

Query: 6108 RENQKNFSLLQYQCDLKNS-KGK-ITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIG 6165
            ++  +  S   Y+ DL+   KGK + V  DT ++ R K+  +  S   YK+D+       
Sbjct: 475  KKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLE------ 528

Query: 6166 KTPEMMRVKQTQDHISSVKYKEAIGQGTPIP-DLPEVKRVKETQKHISSVMYKEN----L 6220
                                 E  G+G  +  D+P++ R K T +  S   YK+     L
Sbjct: 529  --------------------NEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKML 568

Query: 6221 GTGIPTTVTPEIERVKRNQENFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKE 6280
                    TPEI+R+K  Q+N S+V YK+ +G G     +PE+ERVK+NQ+N SSV YKE
Sbjct: 569  SNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKE 628

Query: 6281 NMGKGTPLAVTPEMERVKHNQENISSVLYKENVGKATATPVTPEMQRVKRNQENISSVLY 6340
             +   T ++  PE++RVK NQ+NIS++ YKE   KAT   +TPE++RV+RNQE +S+V Y
Sbjct: 629  EIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKY 688

Query: 6341 KENLGKATPTPFTPEMERVKRNQENFSSVLYKENMRKATPTPVTPEMERAKRNQENISSV 6400
            K  L + T     PE++R K NQ+N S+V Y+  + +AT   VTPEMER K+NQENISSV
Sbjct: 689  KGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSV 748

Query: 6401 LYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFEKHKGC-FTPVVTDPITE 6459
             Y+    KQ++G+ + +LDTP MR V+E Q HIS VKYHEDFEK KG  FTPVV DP+TE
Sbjct: 749  KYTQD-HKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTE 807

Query: 6460 RVKKNMQDFSDINYRGIQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQ 6519
            RV+KN Q  SD  Y+G+   +VEM+++        I  L+VWRT+PGS+FD DP EDNIQ
Sbjct: 808  RVRKNTQVVSDAAYKGVHPHIVEMDRRPG-----IIVDLKVWRTDPGSIFDLDPLEDNIQ 862

Query: 6520 SRSLHMINVQAQ--RRSREQSRSASALSISGGEEKSEHSEAPDH-----HLSTYSDGGVF 6572
            SRSLHM++ +A   RR   +S S+S      G+++SE SE          ++  SD G  
Sbjct: 863  SRSLHMLSEKASHYRRHWSRSHSSSTFGTGLGDDRSEISEIYPSFSCCSEVTRPSDEGAP 922

Query: 6573 AVSTAYKHAKTTELPQQRSSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFK 6632
             +  AY+ + +        +SV++ +    S+   P+   + +RAMYDY A D DEVSF+
Sbjct: 923  VLPGAYQQSHSQGYGYMHQTSVSSMR----SMQHSPNL--RTYRAMYDYSAQDEDEVSFR 976

Query: 6633 DGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            DGD I+NVQ ID+GWMYGTVQRTGRTGMLPANY+E +
Sbjct: 977  DGDYIVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 1013



 Score =  286 bits (733), Expect = 4e-76
 Identities = 250/885 (28%), Positives = 414/885 (46%), Gaps = 91/885 (10%)

Query: 5389 PINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKS 5448
            P+    K  T+   EK    + E+ +  Y  V+++    LA+   + IS I+Y++ ++KS
Sbjct: 4    PVFEDIKDETE--EEKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKS 61

Query: 5449 KDKFTSIVDTPEHLRTTKVNKQISDILY----KLEYNKAKPRGYTTIHDTPMLLHVRKVK 5504
            KDK T + D+P       +   IS+  Y    K + + +  +      D+     V +++
Sbjct: 62   KDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQ 121

Query: 5505 DEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDR 5564
             EV+  K K    +  S+     +   +K A +  K  +N+ Y+K  +     +    DR
Sbjct: 122  SEVA-YKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDR 179

Query: 5565 PDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEK---H 5621
            PD   A + S   S+ EYK  +  +   + +V    +   A+  + + S +KYKEK    
Sbjct: 180  PDIKMATQISKIISNAEYKKGQGIMNK-EPAVIGRPDFEHAVEASKLSSQIKYKEKFDNE 238

Query: 5622 VKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVT 5681
            +K++   +   ++      +  + L S  KYK  ++        + LP      HV + +
Sbjct: 239  MKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQN--MHDPVSDLPNLLFLDHVLKAS 296

Query: 5682 KHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVAD 5741
            K +S   YKK F + KG  ++                          DA E+LH+     
Sbjct: 297  KMLSGREYKKLFEENKGMYHFD------------------------ADAVEHLHH----- 327

Query: 5742 RPDIKKATQAAKQASEVEYRAKHRK-EGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFD 5800
                      A   S+V+Y+ ++ K +G   L  +  P  + +K+A K+ S+  Y+E+F+
Sbjct: 328  -------KGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFE 380

Query: 5801 KE-KGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLKK--LHKPVTDMKESLIMNHVLN 5857
            KE KG++     K  +   V K   NL  E +YK DL+     K +    E L +     
Sbjct: 381  KEIKGRSSLDLDKTPEFLHV-KYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKR 439

Query: 5858 TSQLASSYQYKKKYE---KSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKE-RGKP 5913
             S++AS  +YKK  E   K KG      D LE  H K+A E+ S   YK   E E +GK 
Sbjct: 440  ASEMASEKEYKKDLESIIKGKG-MQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKG 498

Query: 5914 M-LDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEK 5972
            M +  +T     AK++ +M S K+Y+KD E  IKG+ +      P +L  K  ++I S++
Sbjct: 499  MQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQR 558

Query: 5973 EYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETP 6032
            +Y+ + E+ +     + + DTP++ R K   Q ++   YK+++       G      ++P
Sbjct: 559  KYKDEAEKML--SNYSTIADTPEIQRIKTTQQNISAVFYKKEV-------GAGTAVKDSP 609

Query: 6033 DFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSM 6092
            +  R +      S +KYK+    E  + T++ D PE+   ++ +   S  +YKE   K+ 
Sbjct: 610  EIERVKKNQQNISSVKYKE----EIKHATAISDPPELKRVKENQKNISNLQYKEQNYKA- 664

Query: 6093 SYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSV 6152
                 V  TPEI+RVR NQ+  S ++Y+ +L+      T + D PE+ R KENQKN S+V
Sbjct: 665  ---TPVSMTPEIERVRRNQEQLSAVKYKGELQRG----TAISDPPELKRAKENQKNISNV 717

Query: 6153 LYKEDVSPGTAIGKTPEMMRVKQTQDHISSVKY----KEAIGQGTPIPDLPEVKRVKETQ 6208
             Y+  +   T +  TPEM RVK+ Q++ISSVKY    K+  G+ + I D P ++ VKE Q
Sbjct: 718  YYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQ 777

Query: 6209 KHISSVMYKENL----GTGI-PTTVTPEIERVKRNQENFSSVLYK 6248
             HIS V Y E+     G G  P    P  ERV++N +  S   YK
Sbjct: 778  NHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822



 Score =  207 bits (528), Expect = 2e-52
 Identities = 215/847 (25%), Positives = 385/847 (45%), Gaps = 66/847 (7%)

Query: 486  DQCKDHTY--KVHPDKTKFTQVTDSPVLLQAQVN-----SKQLSDLNYKAKHESEKFKCH 538
            +  KD T   K+  ++ +  QV   PV+    +      ++ +SD+ YK + +  K KC 
Sbjct: 7    EDIKDETEEEKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCT 66

Query: 539  IPPDTPAFIQHKVNAYNLSDNLYK----QDWEKSKAKKFDIKVDAIPLLAAKANTKNTSD 594
               D+P     K     +S+  YK     D   S  K+    +D++    A   T+  S+
Sbjct: 67   FVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSV---FAGEVTQLQSE 123

Query: 595  VMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPK 654
            V YK+ ++  KG       + + P++ H+++V K+QS+  Y+++ + T   S    + P 
Sbjct: 124  VAYKQKHDAAKG-FSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAEL-DRPD 181

Query: 655  YQLDTQL-KNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEED- 712
             ++ TQ+ K  S A YK    + ++      +  P   H ++ +  +S   YK +++ + 
Sbjct: 182  IKMATQISKIISNAEYKK--GQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEM 239

Query: 713  KGKCYFPQTITQEYEAIKKLDQCKDHTYKVHPD-KTKFTAVTDSPVLL---QAQLNTKQL 768
            K K +    +        +L        K   D +     V+D P LL        +K L
Sbjct: 240  KDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKML 299

Query: 769  SDLNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIP 828
            S   YK   E  K   H  ADA + + H+ NA   S   YK+++EK+K K     V+   
Sbjct: 300  SGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPS 359

Query: 829  LLAAKANTKNTSDVMYKKDYEKS-KGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYE 887
              A+K   K  S+ +YK+D+EK  KG+   +L ++  P+ LH         ++EY+KD E
Sbjct: 360  YQASKEAQKMQSEKVYKEDFEKEIKGR--SSLDLDKTPEFLHVKYITNLLREKEYKKDLE 417

Query: 888  ---KSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILHS------YSYPPDSINVDLAKK 938
               K K +     ++L + +AK++  +AS+ +YK  L S           D++ +  AKK
Sbjct: 418  NEIKGKGM-ELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKK 476

Query: 939  AYALQSDVEYKADYNSWMKGCGW-VPFGSLEMEKAKRASDILNEKKYRQH-PDTLKFTSI 996
            A  + S+ +YK D  + +KG G  V   +L++++AK+AS++ ++K+Y++   + +K   +
Sbjct: 477  AAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGM 536

Query: 997  E---DAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYK 1053
            +   D P  +++K      S   YK + E+++  Y+   D P+  + K    NIS   YK
Sbjct: 537  QVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYK 596

Query: 1054 ADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVH 1113
             ++      G  ++ D+  I   K  +Q  S V+YK++ + A        ++ D P+L  
Sbjct: 597  KEV----GAGTAVK-DSPEIERVKKNQQNISSVKYKEEIKHA-------TAISDPPELKR 644

Query: 1114 YMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPD 1173
                 K  S+ +YK+   K      TP     +   ++ Q+ +S V YK  L   T + D
Sbjct: 645  VKENQKNISNLQYKEQNYKATPVSMTP----EIERVRRNQEQLSAVKYKGELQRGTAISD 700

Query: 1174 AMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPD 1233
              +L+ +K   Q    NVY          +   P    ++E+VKK  + ++  KY Q   
Sbjct: 701  PPELKRAKE-NQKNISNVYYRGQLGRATTLSVTP----EMERVKKNQENISSVKYTQDHK 755

Query: 1234 TLKF--TSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHK-YTMSPDLPQFLQAKCNAYN 1290
             +K   + I+D+P M   K+    +S + Y    E  K + +T   D P   + + N   
Sbjct: 756  QMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV 815

Query: 1291 ISDVCYK 1297
            +SD  YK
Sbjct: 816  VSDAAYK 822



 Score =  203 bits (517), Expect = 4e-51
 Identities = 219/895 (24%), Positives = 374/895 (41%), Gaps = 129/895 (14%)

Query: 4400 FRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILY 4459
            ++ V++   + LA+  +   SD++YKE F K+K K TF  D+P ++H K++G   S   Y
Sbjct: 30   YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKY 89

Query: 4460 KGAWEGTKAYG-YTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGV 4518
            KG  +   +   Y      I  V A     + SE+ YK+ ++  KG +     + E P V
Sbjct: 90   KGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG-FSDYAHMKEPPEV 148

Query: 4519 VHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSL 4578
             H ++  K +S ++YRK  +DT                                H +++ 
Sbjct: 149  KHAMEVNKHQSNISYRKDVQDT--------------------------------HTYSAE 176

Query: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY-----VWDTPQILHAKKSYDLQSQLQ 4633
            L+ P++       +I+S+  YK      KG G       V   P   HA ++  L SQ++
Sbjct: 177  LDRPDIKMATQISKIISNAEYK------KGQGIMNKEPAVIGRPDFEHAVEASKLSSQIK 230

Query: 4634 YTA----AGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDY 4689
            Y        K+   +YN +         + + + AS VKYK++   + D  + +   +  
Sbjct: 231  YKEKFDNEMKDKKHHYNPLESASFRQNQLAATL-ASNVKYKKDIQNMHDPVSDLPNLLFL 289

Query: 4690 DRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKA 4749
            D       + S   YK+ ++  K   Y   +  +   H K    L S +KY+EEYEK K 
Sbjct: 290  DHVLKASKMLSGREYKKLFEENKG-MYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKG 348

Query: 4750 LYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKN-KMKIHIVPDMV-EMVTAKDSQKK 4807
               L     + P+        K+  +++Y+  +EK  K +  +  D   E +  K     
Sbjct: 349  KPML--EFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNL 406

Query: 4808 VSEIDYRLRLHEWICHPDLQVNDHV------RKVTDQISDIVYKDDL-NWLKGIGCYV-W 4859
            + E +Y+  L   I    +++N  V      ++ ++  S+  YK DL + +KG G     
Sbjct: 407  LREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGT 466

Query: 4860 DTPEILHAKHAYDLRDDIKYKAHMLKTR---NDYKLVTDTPVYVQAVKSGKQLSDAVYHY 4916
            DT E+ HAK A ++  +  YK   L+T       ++ TDT    +A K+ +  S   Y  
Sbjct: 467  DTLEMQHAKKAAEIASEKDYKRD-LETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKK 525

Query: 4917 DYVHSVRGKVAPTTKTV-DLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKD 4975
            D  + ++GK    +  + D+ RA    ++ S   YK     + + Y    DTP  + IK 
Sbjct: 526  DLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKT 585

Query: 4976 TRYMSSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVN--NVTSERLYRELYHKLKDKIH 5033
            T+   S   YK      K  G     KD P +   + N  N++S +   E+ H       
Sbjct: 586  TQQNISAVFYK------KEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHAT----- 634

Query: 5034 TTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKE 5093
               D PE+++VK+ Q+ +S L YK   +K       +  TP++   R   +  S +KYK 
Sbjct: 635  AISDPPELKRVKENQKNISNLQYKEQNYK----ATPVSMTPEIERVRRNQEQLSAVKYKG 690

Query: 5094 DLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELK 5153
            +LQ     G  + D P++ R++  +K  SN  Y    R    +   +  TPE  +V++ +
Sbjct: 691  ELQ----RGTAISDPPELKRAKENQKNISNVYY----RGQLGRATTLSVTPEMERVKKNQ 742

Query: 5154 THLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQT 5213
             ++S + Y    K+ K   + + DTP +   K  Q                         
Sbjct: 743  ENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQ------------------------- 777

Query: 5214 TALKHAKDVKDMVSEKKYKIQYEKMKDK-YTPVPDTPILIRAKRAYWNASDLRYK 5267
                      + +S  KY   +EK K + +TPV D P+  R ++     SD  YK
Sbjct: 778  ----------NHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822



 Score =  201 bits (510), Expect = 3e-50
 Identities = 224/859 (26%), Positives = 372/859 (43%), Gaps = 108/859 (12%)

Query: 602  EKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQL 661
            E+N+   +    + +D  M  + K  +  SD  YKE ++K+K K     ++P       +
Sbjct: 21   EENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNI 80

Query: 662  KNF-SEARYKDLYVKDVLGHYVGSMEDPYHT-HCMKVAAQNSDKSYKAEYEEDKGKCYFP 719
              F SEA+YK     D+       M     +    +V    S+ +YK +++  KG  +  
Sbjct: 81   GAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG--FSD 138

Query: 720  QTITQEYEAIKKLDQCKDHTYKVH-----PDKTKFTAVTDSPVLLQAQLNTKQLSDLNYK 774
                +E   +K   +   H   +       D   ++A  D P +  A   +K +S+  YK
Sbjct: 139  YAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYK 198

Query: 775  AKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNV-YKQDWEKSKAKKFDIKVDAIPLLAAK 833
             K +G   K       P F +H V A  LS  + YK+ ++     K   K    PL +A 
Sbjct: 199  -KGQGIMNKEPAVIGRPDF-EHAVEASKLSSQIKYKEKFDNEMKDK---KHHYNPLESAS 253

Query: 834  ANTKN-----TSDVMYKKDYEKSKGKMIGALSINDDPKML---HSLKTAKNQSDREYRKD 885
                       S+V YKKD +           ++D P +L   H LK +K  S REY+K 
Sbjct: 254  FRQNQLAATLASNVKYKKDIQNMHDP------VSDLPNLLFLDHVLKASKMLSGREYKKL 307

Query: 886  YEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILHSYSYPP-----DSINVDLAKKAY 940
            +E++K +Y    D ++    K +  + S V YK         P     ++ +   +K+A 
Sbjct: 308  FEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQ 367

Query: 941  ALQSDVEYKADYNSWMKGCGWVPFGSLEMEKA------KRASDILNEKKYRQHPDTLKFT 994
             +QS+  YK D+   +KG       SL+++K       K  +++L EK+Y++  +     
Sbjct: 368  KMQSEKVYKEDFEKEIKGRS-----SLDLDKTPEFLHVKYITNLLREKEYKKDLEN---- 418

Query: 995  SIEDAPITVQSKINQAQR--------SDIAYKAKGEEIIHKYNLPP--DLPQFIQAKVNA 1044
             I+   + + S++   QR        S+  YK   E II    +    D  +   AK  A
Sbjct: 419  EIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAA 478

Query: 1045 YNISENMYKADLK-DLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYE-KAKGKMVGF 1102
               SE  YK DL+ ++  KG  + TD + ++ AK A + AS  QYKKD E + KGK  G 
Sbjct: 479  EIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGK--GM 536

Query: 1103 QSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHD----------MFNVVAA--- 1149
            Q   D P ++     ++I S R+YK + EK  S Y+T  D            N+ A    
Sbjct: 537  QVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYK 596

Query: 1150 ------------------KKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNV 1191
                              KK Q  +S+V YK  + H T + D  +L+  K   +  S+  
Sbjct: 597  KEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQ 656

Query: 1192 YKEDYNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQ 1251
            YKE  N     +   P    ++E+V++  + L+  KY+   +  + T+I D P + +AK+
Sbjct: 657  YKEQ-NYKATPVSMTP----EIERVRRNQEQLSAVKYKG--ELQRGTAISDPPELKRAKE 709

Query: 1252 NTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVL 1311
            N K +S++ Y+ +      + T     P+  + K N  NIS V Y +D   +  + + +L
Sbjct: 710  NQKNISNVYYRGQ----LGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLIL 765

Query: 1312 GDAIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYK 1371
             D   +   K ++N  S  KY E +EK+KG+  GF  + DDP         ++ SD  YK
Sbjct: 766  -DTPAMRHVKEAQNHISMVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 822

Query: 1372 KNYENTKTSYHTPGDMVSI 1390
              + +       PG +V +
Sbjct: 823  GVHPHIVEMDRRPGIIVDL 841



 Score =  199 bits (505), Expect = 1e-49
 Identities = 209/819 (25%), Positives = 368/819 (44%), Gaps = 62/819 (7%)

Query: 89  SQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYR--MDGDVAKT 146
           ++K  +L S  +YKE+F+K+K +     TD+P L  +K +   +SE KY+  +  D++ +
Sbjct: 42  ARKCTELISDIRYKEEFKKSKDK-CTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNS 100

Query: 147 ICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTK--DKYLLPPDAPELVQAVKNTAMFSK 204
           +        D   A +V+Q  S+V YKQ  +  K    Y    + PE+  A++     S 
Sbjct: 101 LYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSN 160

Query: 205 KLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEF 264
             Y +D + D   +    D P+++   Q  K +S+  YKKG      +   +   PD E 
Sbjct: 161 ISYRKDVQ-DTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKE-PAVIGRPDFEH 218

Query: 265 AKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMN---ADNISTRKYQEDFENMKD 321
           A + +   S+ KYKE ++N++K K       E A+ R N   A   S  KY++D +NM D
Sbjct: 219 AVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHD 278

Query: 322 QIYFMQTETPEYKMNK---KAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAA 378
            +    ++ P         KA    S  +YK+ +E+NKG   ++         +  L   
Sbjct: 279 PV----SDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDA------DAVEHLHHK 328

Query: 379 GDAL--SDKLYKENYEKTKAK-SINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGH-Y 434
           G+A+  S   YKE YEK K K  + + ETP ++     Q   S+K YK+ + K+I G   
Sbjct: 329 GNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSS 388

Query: 435 VGSFEDPYHSHCMKVTAQNSDKNYKAEYE-EDRGKGFFPQTITQEYEAIKKL-DQCKDHT 492
           +   + P   H   +T    +K YK + E E +GKG    +   + +  K+  +   +  
Sbjct: 389 LDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKE 448

Query: 493 YKVHPD---KTKFTQV-TDSPVLLQAQVNSKQLSDLNYKAKHESE-KFK-CHIPPDTPAF 546
           YK   +   K K  Q  TD+  +  A+  ++  S+ +YK   E+E K K   +  DT   
Sbjct: 449 YKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDV 508

Query: 547 IQHKVNAYNLSDNLYKQDWEKS-KAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNK 605
            + K  +   S   YK+D E   K K   + +D   +L A    K TS++  ++ Y+   
Sbjct: 509 QRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRA----KRTSEIYSQRKYKDEA 564

Query: 606 GKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQ-LDTQLKNF 664
            KM+   S   D   +  +K  +     ++   Y+K         ++P+ + +    +N 
Sbjct: 565 EKMLSNYSTIADTPEIQRIKTTQQNISAVF---YKKEVGAGTAVKDSPEIERVKKNQQNI 621

Query: 665 SEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQ 724
           S  +Y     K+ + H     + P     +K   +N       +Y+E   K   P ++T 
Sbjct: 622 SSVKY-----KEEIKHATAISDPPE----LKRVKENQKNISNLQYKEQNYKA-TPVSMTP 671

Query: 725 EYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKC 784
           E E +++ +Q +    K   +  + TA++D P L +A+ N K +S++ Y+    G+  + 
Sbjct: 672 EIERVRR-NQEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYR----GQLGRA 726

Query: 785 HIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMY 844
              +  P+  + + N  N+S   Y QD ++ K +   + +D   +   K    + S V Y
Sbjct: 727 TTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKY 785

Query: 845 KKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYR 883
            +D+EK+KG+  G   + DDP      K  +  SD  Y+
Sbjct: 786 HEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 822



 Score =  194 bits (492), Expect = 3e-48
 Identities = 213/902 (23%), Positives = 389/902 (43%), Gaps = 99/902 (10%)

Query: 1461 KKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDP 1520
            +K G+  NE       D V +  V + + M LA+  T+ +SD+ YK E +K K K T   
Sbjct: 16   EKIGEEENEE------DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVT 69

Query: 1521 ELPQFIQAKVNALNMSDAHYKADWKKTIAKG-YDLRPDAIPIVAAKSSRNIASDCKYKEA 1579
            + P     K     +S+A YK   K  ++   Y   P  I  V A     + S+  YK+ 
Sbjct: 70   DSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQK 129

Query: 1580 YEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKK 1639
            ++ AKG    +  +++ P++ H M V K QS+  Y+K  + + T Y   LD   +  A +
Sbjct: 130  HDAAKGFS-DYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDIKMATQ 187

Query: 1640 SQEVATNANYRQSYHHYTLLPDAL---NVEHSRNAMQIQSDNLYKSDFTNWMKG--IGWV 1694
              ++ +NA Y++        P  +   + EH+  A ++ S   YK  F N MK     + 
Sbjct: 188  ISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYN 247

Query: 1695 PIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYA----MDTMEQALNKSNKLNMDKRLYT 1750
            P+ES    + + A  + S  KY++  + +    +    +  ++  L  S  L+   R Y 
Sbjct: 248  PLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLS--GREYK 305

Query: 1751 EKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARA 1810
            + + ++K   H   D  + L  + N +  S   YK  +E+ K K      +  + +A++ 
Sbjct: 306  KLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKE 365

Query: 1811 SRDIASDYKYKKAYE-QAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEK--SKT 1867
            ++ + S+  YK+ +E + KG+      L+  P+ +H   +  +  ++EYKK  E      
Sbjct: 366  AQKMQSEKVYKEDFEKEIKGR--SSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGK 423

Query: 1868 SFHTPVDMLSVVAAKKSQEVATNANYR----NVIHTYNML--PDAMSFELAKNMMQIQSD 1921
                  ++L +  AK++ E+A+   Y+    ++I    M    D +  + AK   +I S+
Sbjct: 424  GMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASE 483

Query: 1922 NQYKADYADFMKGIGW-LPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVL 1980
              YK D    +KG G  +   +L+ ++ KKA E+ S+K+Y++           D  N + 
Sbjct: 484  KDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKK-----------DLENEIK 532

Query: 1981 AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKK--K 2038
             +                     + +  DIP I+ AK  +   S + YK   +E++K   
Sbjct: 533  GKG--------------------MQVSMDIPDILRAKRTSEIYSQRKYK---DEAEKMLS 569

Query: 2039 GYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQS 2098
             Y    D   I+  K ++   S   YK   E G G  V     +D P++    +  +  S
Sbjct: 570  NYSTIADTPEIQRIKTTQQNISAVFYK--KEVGAGTAV-----KDSPEIERVKKNQQNIS 622

Query: 2099 DREYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRN 2158
              +YK+  ++  T+   P ++  V   K+ Q NI+N  YK   +K      A  + +T  
Sbjct: 623  SVKYKEEIKHA-TAISDPPELKRV---KENQKNISNLQYKEQNYK------ATPVSMTPE 672

Query: 2159 MNRIQSDNEYKQDYNEWYKG---LGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKK 2215
            + R++ + E        YKG    G + +   E+++AK+  +  S+  YR          
Sbjct: 673  IERVRRNQEQLSAVK--YKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLS 730

Query: 2216 LTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLG 2275
            +T  M+ V  K+N   ++   YT D  + K +  ++ DTP +   K+ Q   S   Y   
Sbjct: 731  VTPEMERV--KKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHED 788

Query: 2276 WEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSM 2335
            +E+   +G+   VD    +  + +  + SD  YK       G H     +   P +++ +
Sbjct: 789  FEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK-------GVHPHIVEMDRRPGIIVDL 841

Query: 2336 NV 2337
             V
Sbjct: 842  KV 843



 Score =  191 bits (485), Expect = 2e-47
 Identities = 202/837 (24%), Positives = 358/837 (42%), Gaps = 92/837 (10%)

Query: 5002 KDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFF 5061
            +D+     R+   + S+  Y+E + K KDK     D+P +  VK     +SE  YK    
Sbjct: 35   EDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIK 94

Query: 5062 KMQGHMI--SLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLY--DTPDMVRSRHL 5117
                + +   +P T   +    V  + S++ YK+     KGF  + +  + P++  +  +
Sbjct: 95   ADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEV 154

Query: 5118 RKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPD 5177
             K  SN  Y    +     Y   LD P+ +    + T +S+++  A  KK + I    P 
Sbjct: 155  NKHQSNISYRKDVQDTHT-YSAELDRPDIK----MATQISKIISNAEYKKGQGIMNKEPA 209

Query: 5178 T---PDLLRAKRGQKLQSQYLYVEL---ATKERPHHHAGNQTTALKHAKDVKDMVSEKKY 5231
                PD   A    KL SQ  Y E      K++ HH+   ++ + +  +    + S  KY
Sbjct: 210  VIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKY 269

Query: 5232 KIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRK 5291
            K   + M D  + +P+   L    +A    S   YK+ F++ KG YH   DA++ ++H+ 
Sbjct: 270  KKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKG 329

Query: 5292 VTDDISKIKYKENYMSQLG-------------------------IWR------------- 5313
                 S++KYKE Y    G                         +++             
Sbjct: 330  NAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSL 389

Query: 5314 SIPDRPEHFHHRAVTDTVSDVKYKEDL-TWLKGIGC-YAYDTPDFTLAEKNKTLYSKYKY 5371
             +   PE  H + +T+ + + +YK+DL   +KG G     +  D   A++   + S+ +Y
Sbjct: 390  DLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEY 449

Query: 5372 KEVFER--TKSDFKYVADSPINRHFKYATQLMNEKKYRADYE-QRKDK-YHLVVDEPRHL 5427
            K+  E        +   D+   +H K A ++ +EK Y+ D E + K K   +  D     
Sbjct: 450  KKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQ 509

Query: 5428 LAKTAGDQISQIKYRKNYEKS-KDKFTSI-VDTPEHLRTTKVNKQISDILYKLEYNKAKP 5485
             AK A +  SQ +Y+K+ E   K K   + +D P+ LR  + ++  S   YK E  K   
Sbjct: 510  RAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKML- 568

Query: 5486 RGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNL 5545
              Y+TI DTP +  ++  +  +S + YK    +     T   D+  I+  K   +  +++
Sbjct: 569  SNYSTIADTPEIQRIKTTQQNISAVFYK----KEVGAGTAVKDSPEIERVKKNQQNISSV 624

Query: 5546 DYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLA 5605
             YK++ +    H     D P+  +  ++    S+ +YK   +  K   +S+T +   V  
Sbjct: 625  KYKEEIK----HATAISDPPELKRVKENQKNISNLQYK--EQNYKATPVSMTPEIERV-- 676

Query: 5606 LRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSY 5665
             RN    S +KYK +   +RGT  A+ D P++  AK     +S   Y+  +      G  
Sbjct: 677  RRNQEQLSAVKYKGE--LQRGT--AISDPPELKRAKENQKNISNVYYRGQL------GRA 726

Query: 5666 TTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVA 5725
            TTL  T +   VK+  +++S   Y +   + KG+   S++L+ P ++H  E     S V 
Sbjct: 727  TTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRP--SLILDTPAMRHVKEAQNHISMVK 784

Query: 5726 YRKDAK--ENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLGRPDI 5780
            Y +D +  +   +T V D P  ++  +  +  S+  Y+  H     H + M  RP I
Sbjct: 785  YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH----PHIVEMDRRPGI 837



 Score =  189 bits (481), Expect = 6e-47
 Identities = 214/845 (25%), Positives = 376/845 (44%), Gaps = 81/845 (9%)

Query: 5220 KDVKDMVSEKKYKIQYEKMKDK--YTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKY 5277
            +D+KD   E+K   + E  +D+  Y PV +   +  A++     SD+RYKE F+K+K K 
Sbjct: 7    EDIKDETEEEKIG-EEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKC 65

Query: 5278 HTVKDALDIVYHRKVTDDISKIKYKENYMSQL--GIWRSIPDRPEHFHHRAVTDTVSDVK 5335
              V D+  + + + +   IS+ KYK    + L   +++ +P   +      VT   S+V 
Sbjct: 66   TFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVA 125

Query: 5336 YKEDLTWLKGIGCYAY------------------------------------DTPDFTLA 5359
            YK+     KG   YA+                                    D PD  +A
Sbjct: 126  YKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMA 185

Query: 5360 EKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYE-QRKDKYH 5418
             +   + S  +YK+  +   +    V   P   H   A++L ++ KY+  ++ + KDK H
Sbjct: 186  TQISKIISNAEYKK-GQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKH 244

Query: 5419 LV--VDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQISDILY 5476
                ++       + A    S +KY+K+ +   D  + + +        K +K +S   Y
Sbjct: 245  HYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREY 304

Query: 5477 KLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIE-PDAVHIKAA 5535
            K  + + K   Y    D    LH +      S +KYKE Y++NK    +E  +    +A+
Sbjct: 305  KKLFEENKGM-YHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQAS 363

Query: 5536 KDAYKVNTNLDYKKQYEAN-KAHWKWTPDR-PDFLQAAKSSLQQSDFEYKLDRE-FLKGC 5592
            K+A K+ +   YK+ +E   K       D+ P+FL     +    + EYK D E  +KG 
Sbjct: 364  KEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGK 423

Query: 5593 KLSVTDDKNTV-LALRNTLIESDLKYK---EKHVKERGTCHAVPDTPQILLAKTVSNLVS 5648
             + +  +   +  A R + + S+ +YK   E  +K +G   A  DT ++  AK  + + S
Sbjct: 424  GMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKG-MQAGTDTLEMQHAKKAAEIAS 482

Query: 5649 ENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEP 5708
            E  YK  ++  +         +T D    K+ ++  S   YKK    E       + ++ 
Sbjct: 483  EKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDI 542

Query: 5709 PEVKHAMEVAKKQSDVAYRKDAKENL-HYTTVADRPDIKKATQAAKQASEVEYRAKHRKE 5767
            P++  A   ++  S   Y+ +A++ L +Y+T+AD P+I++     +  S V Y    +KE
Sbjct: 543  PDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFY----KKE 598

Query: 5768 GSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLA 5827
               G ++   P+IE  KK  +  S VKY+E     K  T   +P   +L +V ++  N+ 
Sbjct: 599  VGAGTAVKDSPEIERVKKNQQNISSVKYKEEI---KHATAISDP--PELKRVKENQKNI- 652

Query: 5828 SEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQ 5887
            S ++YK    K   PV+   E   +  V    +  S+ +YK + ++       I D  E 
Sbjct: 653  SNLQYKEQNYKA-TPVSMTPE---IERVRRNQEQLSAVKYKGELQRGT----AISDPPE- 703

Query: 5888 LHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEESIKG 5947
              LK A E Q  +     Y  + G+      TP     K++Q+  S  +Y +D+++ +KG
Sbjct: 704  --LKRAKENQKNIS-NVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQ-MKG 759

Query: 5948 RNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILN 6007
            R    L+ TPA+ HVK A    S  +Y +D E++ +G+G T + D P   R +  TQ+++
Sbjct: 760  RPSLILD-TPAMRHVKEAQNHISMVKYHEDFEKT-KGRGFTPVVDDPVTERVRKNTQVVS 817

Query: 6008 EKEYK 6012
            +  YK
Sbjct: 818  DAAYK 822



 Score =  176 bits (447), Expect = 5e-43
 Identities = 209/828 (25%), Positives = 352/828 (42%), Gaps = 89/828 (10%)

Query: 4156 FTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYT-LTETPLLHTAQEAARILDQYLY 4214
            + PV + +    A++  E++ DI+Y++++  +K K T +T++P+L+  +     + +  Y
Sbjct: 30   YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKY 89

Query: 4215 KEGWERQKATG-YILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKL 4273
            K   +   +   Y   P  +  V A     +QSE+ YK +H   KG +     M++ P++
Sbjct: 90   KGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG-FSDYAHMKEPPEV 148

Query: 4274 VWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYR------NYL 4327
                   + Q+   Y++D   T    +   D   +  A Q   ++S+ +Y+      N  
Sbjct: 149  KHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDIKMATQISKIISNAEYKKGQGIMNKE 207

Query: 4328 HQWMCHPDQNDVIQARK-----------------------------------AYDLQSDN 4352
               +  PD    ++A K                                   A  L S+ 
Sbjct: 208  PAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNV 267

Query: 4353 VYRADLEWLRG-IGWIP-LDSVDHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIV 4410
             Y+ D++ +   +  +P L  +DHV   K  +M+S  +YKK   EN   +    D  E +
Sbjct: 268  KYKKDIQNMHDPVSDLPNLLFLDHV--LKASKMLSGREYKKLFEENKGMYHFDADAVEHL 325

Query: 4411 LAKINSVNQSDVKYKETFNKAKGKYTFS-PDTPHISHSKDMGKLYSTILYKGAWEGTKAY 4469
              K N+V QS VKYKE + K KGK      +TP    SK+  K+ S  +YK  +E     
Sbjct: 326  HHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKG 385

Query: 4470 GYTLDERYIP-IVGAKHADLVNSELKYKETYE---KQKGHYLAGKVIGEFPGVVHCLDFQ 4525
              +LD    P  +  K+   +  E +YK+  E   K KG  L  +V+     +       
Sbjct: 386  RSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLD----IQRAKRAS 441

Query: 4526 KMRSALNYRKHYEDT--KANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTS------ 4577
            +M S   Y+K  E       +    D +    AK+   I S+ +Y+              
Sbjct: 442  EMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQV 501

Query: 4578 LLEEPNVIRVRNAQEILSDNVYKDDL-NWLKGIGCYV-WDTPQILHAKKSYDLQSQLQYT 4635
              +  +V R + A E+ S   YK DL N +KG G  V  D P IL AK++ ++ SQ +Y 
Sbjct: 502  STDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYK 561

Query: 4636 AAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNL 4695
               ++ L NY+ + DTP       +  N S V YK+         T V ++ + +R +  
Sbjct: 562  DEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEV----GAGTAVKDSPEIERVKKN 617

Query: 4696 KNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPR 4755
            +   SS  YKE    +K  + I     L     +NQK++ S+++Y+E+   +KA      
Sbjct: 618  QQNISSVKYKE---EIKHATAISDPPELKRVK-ENQKNI-SNLQYKEQ--NYKAT----- 665

Query: 4756 SVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRL 4815
             V   P   R  R    N ++L    Y+    +   + D  E+  AK++QK +S + YR 
Sbjct: 666  PVSMTPEIERVRR----NQEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRG 721

Query: 4816 RLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRD 4875
            +L            + V+K  + IS + Y  D   +KG    + DTP + H K A +   
Sbjct: 722  QLGRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHIS 781

Query: 4876 DIKYKAHMLKTRN-DYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSV 4922
             +KY     KT+   +  V D PV  +  K+ + +SDA Y   + H V
Sbjct: 782  MVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIV 829



 Score =  174 bits (440), Expect = 3e-42
 Identities = 218/835 (26%), Positives = 374/835 (44%), Gaps = 84/835 (10%)

Query: 863  DDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILH 922
            +D  M  + K  +  SD  Y+++++KSK   T   D   +   K   A  S+  YK  + 
Sbjct: 35   EDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIK 94

Query: 923  S------YSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLE-------- 968
            +      Y   P +I+   A +   LQS+V YK  +++     G+  +  ++        
Sbjct: 95   ADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDA---AKGFSDYAHMKEPPEVKHA 151

Query: 969  MEKAKRASDILNEKKYRQHPDTLKFTSIEDAP-ITVQSKINQAQRSDIAYKAKGEEIIHK 1027
            ME  K  S+I   K  +   DT  +++  D P I + ++I++   S+  YK KG+ I++K
Sbjct: 152  MEVNKHQSNISYRKDVQ---DTHTYSAELDRPDIKMATQISKII-SNAEYK-KGQGIMNK 206

Query: 1028 YNLPPDLPQFIQAKVNAYNISENMYKA----DLKDLSKKGYDLRTDAIPIRAAKAARQAA 1083
                   P F  A   +   S+  YK     ++KD  KK +    ++   R  + A   A
Sbjct: 207  EPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKD--KKHHYNPLESASFRQNQLAATLA 264

Query: 1084 SDVQYKKDYEKAKGKMVGFQSLQDDPKLV---HYMNVAKIQSDREYKKDYEKTKSKYNTP 1140
            S+V+YKKD +           + D P L+   H +  +K+ S REYKK +E+ K  Y+  
Sbjct: 265  SNVKYKKDIQNMH------DPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFD 318

Query: 1141 HDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLP-----DAMDLELSKNMMQIQSDNVYKED 1195
             D    +  K    + S V YK         P     +    + SK   ++QS+ VYKED
Sbjct: 319  ADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKED 378

Query: 1196 YNNWMKGIGWIPIGSLDVEK------VKKAGDALNEKKYRQHPDT-LKFTSI-VDSPVM- 1246
            +   +KG       SLD++K      VK   + L EK+Y++  +  +K   + ++S V+ 
Sbjct: 379  FEKEIKGRS-----SLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLD 433

Query: 1247 -VQAKQNTKQVSDILYKAKGEDVKHKYTMSP--DLPQFLQAKCNAYNISDVCYKRDWH-D 1302
              +AK+ ++  S+  YK   E +     M    D  +   AK  A   S+  YKRD   +
Sbjct: 434  IQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETE 493

Query: 1303 LIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKS-KGKHVGFRSLQDDPKLVHYMNV 1361
            +  KG  V  D + +  AK +  +AS  +YK+  E   KGK  G +   D P ++     
Sbjct: 494  IKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGK--GMQVSMDIPDILRAKRT 551

Query: 1362 AKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSL 1421
            +++ S R+YK   E   ++Y T  D   I   K  Q   + V YK+ +   T + D+  +
Sbjct: 552  SEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEI 611

Query: 1422 EHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKF 1481
            E  +   Q  S   YK+E       I   P    E+++VK+    ++  +Y++     K 
Sbjct: 612  ERVKKNQQNISSVKYKEEI-KHATAISDPP----ELKRVKENQKNISNLQYKE--QNYKA 664

Query: 1482 TSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYK 1541
            T V  +  +   + N +QLS + YK  GE  +     DP  P+  +AK N  N+S+ +Y+
Sbjct: 665  TPVSMTPEIERVRRNQEQLSAVKYK--GELQRGTAISDP--PELKRAKENQKNISNVYYR 720

Query: 1542 ADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVH 1601
                +  A    + P+   +   K+  NI+S  KY + +++ KG+    L   D P + H
Sbjct: 721  GQLGR--ATTLSVTPEMERV--KKNQENISS-VKYTQDHKQMKGRPSLIL---DTPAMRH 772

Query: 1602 YMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVT-AAKKSQEVATNANYRQSYHH 1655
                    S  +Y + +E +K +  TP+    VT   +K+ +V ++A Y+  + H
Sbjct: 773  VKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 827



 Score =  167 bits (423), Expect = 3e-40
 Identities = 202/863 (23%), Positives = 360/863 (41%), Gaps = 114/863 (13%)

Query: 1785 KAGWEEEKKKGYDLRP--DAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPK 1842
            K G EE ++     +P  + ++++ AR   ++ SD +YK+ ++++K K      + D P 
Sbjct: 17   KIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDK---CTFVTDSPM 73

Query: 1843 LVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNM 1902
            L H   +    S+ +YK                   + A  S  +            Y  
Sbjct: 74   LNHVKNIGAFISEAKYK-----------------GTIKADLSNSL------------YKR 104

Query: 1903 LPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKK--- 1959
            +P  +    A  + Q+QS+  YK  + D  KG         E  + K AME+   +    
Sbjct: 105  MPATIDSVFAGEVTQLQSEVAYKQKH-DAAKGFSDYA-HMKEPPEVKHAMEVNKHQSNIS 162

Query: 1960 YRQH-PDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIM--PDIPQIILA 2016
            YR+   DT  YS  +D  ++ +A   +KI++   YK+       +  ++  PD    +  
Sbjct: 163  YRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAV-- 220

Query: 2017 KANAINMSDKLYKLSLEESKKKGYDLRP-DAIPIKAAKASRDIASDYKYKYNYEKGKGKM 2075
            +A+ ++   K  +    E K K +   P ++   +  + +  +AS+ KYK + +     +
Sbjct: 221  EASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPV 280

Query: 2076 VGFRSLEDDPKLV---HSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANI 2132
                   D P L+   H ++ +KM S REYKK +E  K  YH  AD +     K      
Sbjct: 281  ------SDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQ 334

Query: 2133 TNTNYKHLIHKYILLP-----DAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSL 2187
            +   YK    K    P     +  + + ++   ++QS+  YK+D+ +  KG       SL
Sbjct: 335  SQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKG-----RSSL 389

Query: 2188 EVEKA------KKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDW 2241
            +++K       K  T    +++Y++   N    K  +    VL  Q A   ++     ++
Sbjct: 390  DLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEY 449

Query: 2242 NKDKTKI------HVMPDTPDILQAKQNQTLYSQKLYKLGWEEALK-KGYDLPVDAISVQ 2294
             KD   I          DT ++  AK+   + S+K YK   E  +K KG  +  D + VQ
Sbjct: 450  KKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQ 509

Query: 2295 LAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWK 2354
             AK + ++AS  +YK+    ++    G +   D P ++ +   +++ S+R+YK + EK  
Sbjct: 510  RAKKASEMASQKQYKKDLENEIKGK-GMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKML 568

Query: 2355 TKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKS 2414
            + +S+  D   +   K  Q+ +S V YK  +   T + D  ++ + KK  +  S   YK 
Sbjct: 569  SNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKE 628

Query: 2415 DLEWLRGIGWSP-----------LGSL----------------EAEKNKRASEIISEKKY 2447
            +++    I   P           + +L                E E+ +R  E +S  KY
Sbjct: 629  EIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKY 688

Query: 2448 RQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANL 2507
            +    R   T+I D  ++  AK N KN S+  YR    +  T    +  TP++   K N 
Sbjct: 689  KGELQRG--TAISDPPELKRAKENQKNISNVYYRGQLGRATT----LSVTPEMERVKKNQ 742

Query: 2508 INTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARN 2567
             N S   Y   ++++K +   L +D   ++  K ++   S  KY E F K  G   G   
Sbjct: 743  ENISSVKYTQDHKQMKGRP-SLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGR--GFTP 799

Query: 2568 IEDDPKMMWSMHVAKIQSDREYK 2590
            + DDP         ++ SD  YK
Sbjct: 800  VVDDPVTERVRKNTQVVSDAAYK 822



 Score =  166 bits (420), Expect = 7e-40
 Identities = 220/949 (23%), Positives = 388/949 (40%), Gaps = 133/949 (14%)

Query: 3181 DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYS 3240
            D++ +  V + L   LA+     ++   Y E + K K +   + D+P +   +      S
Sbjct: 26   DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFIS 85

Query: 3241 ESLYRQAME-EAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHD 3299
            E+ Y+  ++ +     Y      I  V A     + S+  YK+ +    G    A  + +
Sbjct: 86   EAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAH-MKE 144

Query: 3300 DPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHP--- 3356
             P++  ++ + K QS+  Y+KD +   T YS+ +D   I +A +   ++S+ +YK     
Sbjct: 145  PPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDIKMATQISKIISNAEYKKGQGI 203

Query: 3357 LHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWM---KGIGWVPIDSLEVVRAKRAGEL 3413
            +++   +  + D  HA +A  L S   YK   +     K   + P++S    + + A  L
Sbjct: 204  MNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATL 263

Query: 3414 LSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIM 3473
             S+  Y++  + +    ++D P  +L  ++ L  +K L                      
Sbjct: 264  ASNVKYKKDIQNMH-DPVSDLPN-LLFLDHVLKASKML---------------------- 299

Query: 3474 LAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGH 3533
                     S + YK   EE+K   Y    DA+     K +  + S  KYKE Y K  G 
Sbjct: 300  ---------SGREYKKLFEENKGM-YHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGK 349

Query: 3534 HIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSD 3593
             +      + P    S    K+QS++ YK++FEK + K  S +D                
Sbjct: 350  PM--LEFVETPSYQASKEAQKMQSEKVYKEDFEK-EIKGRSSLD---------------- 390

Query: 3594 IDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLE-WLRGIGWVPIGSV-EVEKVK 3651
                        L    + +  +   +L  +  YK DLE  ++G G      V ++++ K
Sbjct: 391  ------------LDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAK 438

Query: 3652 RAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPD 3711
            RA E+ S+++Y++           D   I+  K                     +    D
Sbjct: 439  RASEMASEKEYKK-----------DLESIIKGKG--------------------MQAGTD 467

Query: 3712 TPDILLAKSNSANISQKLYTKGWD-ESKMKDYDLRADAISIKSAKASRDIASDYKYKEAY 3770
            T ++  AK  +   S+K Y +  + E K K   +  D + ++ AK + ++AS  +YK+  
Sbjct: 468  TLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDL 527

Query: 3771 EKQ-KGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKK 3829
            E + KG   G Q   D P I+ A    +I S+R+YK E +K  + +S+  D   I   K 
Sbjct: 528  ENEIKGK--GMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKT 585

Query: 3830 CQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPE 3889
             Q  ++ + Y+  +   T + D  +I + KK     S   YK +++    I       PE
Sbjct: 586  TQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHATAI----SDPPE 641

Query: 3890 VLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSI 3949
            + RVK  Q    +  Y+    N K T +  TPE+   + N E +S  KY+    +     
Sbjct: 642  LKRVKENQKNISNLQYKEQ--NYKATPVSMTPEIERVRRNQEQLSAVKYKGELQRGTA-- 697

Query: 3950 HIMPDTPEINLARANALNVSNKLYREGWDEMKAGCDVRLDAIP-IQAAKASREIASDYKY 4008
              + D PE+  A+ N  N+SN  YR      + G    L   P ++  K ++E  S  KY
Sbjct: 698  --ISDPPELKRAKENQKNISNVYYRG-----QLGRATTLSVTPEMERVKKNQENISSVKY 750

Query: 4009 KLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPV--DMLSI 4066
              DH++ KG     L   D   +R    A    +  +Y  D+ K K +  +PV  D ++ 
Sbjct: 751  TQDHKQMKGRPSLIL---DTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTE 807

Query: 4067 LHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKAD 4115
               KN+Q +VSD  Y+        M  +  +I   K +     +++  D
Sbjct: 808  RVRKNTQ-VVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLD 855



 Score =  165 bits (417), Expect = 2e-39
 Identities = 215/851 (25%), Positives = 357/851 (41%), Gaps = 67/851 (7%)

Query: 305  DNISTRKYQEDFENMKDQIYFMQT-ETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNV 363
            D     K  E+ EN +DQ+++    E    ++ +K     S ++YKE+++K+K K  +  
Sbjct: 11   DETEEEKIGEE-ENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTF-- 67

Query: 364  LPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTV----LQNFSSD 419
               +++P L  +K  G  +S+  YK   +   + S+ Y   P   +D+V    +    S+
Sbjct: 68   --VTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSL-YKRMPA-TIDSVFAGEVTQLQSE 123

Query: 420  KKYKDSY-LKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQE 478
              YK  +        Y    E P   H M+V    S+ +Y+ + ++         T + E
Sbjct: 124  VAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQD-------THTYSAE 176

Query: 479  YEA--IKKLDQCKDHTYKVHPDK-----TKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHE 531
             +   IK   Q           K      K   V   P    A   SK  S + YK K +
Sbjct: 177  LDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFD 236

Query: 532  SE-KFKCH--IPPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKAN 588
            +E K K H   P ++ +F Q+++ A   S+  YK+D +       D+  + + L      
Sbjct: 237  NEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLP-NLLFLDHVLKA 295

Query: 589  TKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSM- 647
            +K  S   YKK +E+NKG         D  + LH    A  QS   YKE YEK K K M 
Sbjct: 296  SKMLSGREYKKLFEENKGM---YHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPML 352

Query: 648  NYCETPKYQLDTQLKNF-SEARYKDLYVKDVLGHYVGSME-DPYHTHCMKVAAQNSDKSY 705
             + ETP YQ   + +   SE  YK+ + K++ G     ++  P   H   +     +K Y
Sbjct: 353  EFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEY 412

Query: 706  KAEYE-EDKGKCYFPQTITQEYEAIKKL-DQCKDHTYKVHPDK----TKFTAVTDSPVLL 759
            K + E E KGK     +   + +  K+  +   +  YK   +         A TD+  + 
Sbjct: 413  KKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQ 472

Query: 760  QAQLNTKQLSDLNYKAKHEGE-KFK-CHIPADAPQFIQHRVNAYNLSDNVYKQDWEKS-K 816
             A+   +  S+ +YK   E E K K   +  D     + +  +   S   YK+D E   K
Sbjct: 473  HAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIK 532

Query: 817  AKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKN 876
             K   + +D   +L A    K TS++  ++ Y+    KM+   S   D   +  +KT + 
Sbjct: 533  GKGMQVSMDIPDILRA----KRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQ 588

Query: 877  QSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLA 936
                 +   Y+K     TA  D  ++ + KK+Q   S V YK  +   +   D   +   
Sbjct: 589  NISAVF---YKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHATAISDPPELKRV 645

Query: 937  KKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSI 996
            K+     S+++YK + N         P    E+E+ +R  + L+  KY+   +  + T+I
Sbjct: 646  KENQKNISNLQYK-EQNYKATPVSMTP----EIERVRRNQEQLSAVKYK--GELQRGTAI 698

Query: 997  EDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADL 1056
             D P   ++K NQ   S++ Y+ +    + +       P+  + K N  NIS   Y  D 
Sbjct: 699  SDPPELKRAKENQKNISNVYYRGQ----LGRATTLSVTPEMERVKKNQENISSVKYTQDH 754

Query: 1057 KDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMN 1116
            K + K    L  D   +R  K A+   S V+Y +D+EK KG+  GF  + DDP       
Sbjct: 755  KQM-KGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGR--GFTPVVDDPVTERVRK 811

Query: 1117 VAKIQSDREYK 1127
              ++ SD  YK
Sbjct: 812  NTQVVSDAAYK 822



 Score =  165 bits (417), Expect = 2e-39
 Identities = 193/735 (26%), Positives = 315/735 (42%), Gaps = 73/735 (9%)

Query: 91  KMQDLFSPNKYKEKFEKTKG-QPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICH 149
           ++  L S   YK+K +  KG   YA   + PE++   +V    S + YR D     T   
Sbjct: 116 EVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYS- 174

Query: 150 VDEKAKDIEHAKKVSQQVSKVLYK--QNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKLY 207
            +    DI+ A ++S+ +S   YK  Q   + +   +  PD    V+A K ++    K  
Sbjct: 175 AELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEK 234

Query: 208 TEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAK- 266
            ++   DK   Y   +S   R+   A    S+V YKK +   Q    P++D P++ F   
Sbjct: 235 FDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDI---QNMHDPVSDLPNLLFLDH 291

Query: 267 --KVTNQVSKQKYKEDYENKIKGKWS-ETPCFEVANARMNADNISTRKYQEDFENMKDQI 323
             K +  +S ++YK+ +E   KG +  +    E  + + NA   S  KY+E++E  K + 
Sbjct: 292 VLKASKMLSGREYKKLFEEN-KGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKP 350

Query: 324 YFMQTETPEYKMNKKAGVAASKVKYKEDYEKN-KGKADYNVLPASENPQLRQLKAAGDAL 382
                ETP Y+ +K+A    S+  YKED+EK  KG++    L   + P+   +K   + L
Sbjct: 351 MLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSS---LDLDKTPEFLHVKYITNLL 407

Query: 383 SDKLYK---ENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFE 439
            +K YK   EN  K K   +N  E    +        +S+K+YK      I G  + +  
Sbjct: 408 REKEYKKDLENEIKGKGMELN-SEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGT 466

Query: 440 DPYH-SHCMKVTAQNSDKNYKAEYE-EDRGKGFFPQTITQEYEAIKKL-DQCKDHTYKVH 496
           D     H  K     S+K+YK + E E +GKG    T T + +  KK  +      YK  
Sbjct: 467 DTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKD 526

Query: 497 PD---KTKFTQVT-DSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVN 552
            +   K K  QV+ D P +L+A+  S+  S   YK + E          DTP   + K  
Sbjct: 527 LENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTT 586

Query: 553 AYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVL 612
             N+S   YK++     A K   +++ +     K N +N S V YK++ +          
Sbjct: 587 QQNISAVFYKKEVGAGTAVKDSPEIERV-----KKNQQNISSVKYKEEIKH-------AT 634

Query: 613 SINDDPKMLHSLKVAKNQSDRLYKE-NYEKTKA----------KSMNYCETPKYQLDTQ- 660
           +I+D P++    +  KN S+  YKE NY+ T            ++       KY+ + Q 
Sbjct: 635 AISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKGELQR 694

Query: 661 ---------LKNFSE--ARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEY 709
                    LK   E      ++Y +  LG        P      K     S   Y  ++
Sbjct: 695 GTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVKKNQENISSVKYTQDH 754

Query: 710 EEDKGKCYFPQTITQEYEAIKKLDQCKDH--TYKVHPD--KTK---FTAVTDSPVLLQAQ 762
           ++ KG+     ++  +  A++ + + ++H    K H D  KTK   FT V D PV  + +
Sbjct: 755 KQMKGR----PSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERVR 810

Query: 763 LNTKQLSDLNYKAKH 777
            NT+ +SD  YK  H
Sbjct: 811 KNTQVVSDAAYKGVH 825



 Score =  163 bits (412), Expect = 6e-39
 Identities = 217/935 (23%), Positives = 389/935 (41%), Gaps = 135/935 (14%)

Query: 1947 KNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHI 2006
            K++   E I E++  +  D + Y  +++ ++M LA+   +++++  YK+ ++  K K   
Sbjct: 10   KDETEEEKIGEEENEE--DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTF 67

Query: 2007 MPDIPQIILAKANAINMSDKLYKLSLEESKKKG-YDLRPDAIPIKAAKASRDIASDYKYK 2065
            + D P +   K     +S+  YK +++       Y   P  I    A     + S+  YK
Sbjct: 68   VTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYK 127

Query: 2066 YNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAA 2125
              ++  KG    +  +++ P++ H+M+V K QS+  Y+K+ ++T                
Sbjct: 128  QKHDAAKG-FSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDT---------------- 170

Query: 2126 KDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPA- 2184
                            H Y    D  +I++   +++I S+ EYK+      K     PA 
Sbjct: 171  ----------------HTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNK----EPAV 210

Query: 2185 -GSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYT-IDWN 2242
             G  + E A +A++ +S  KY++   N    K      +  A    + +   L + + + 
Sbjct: 211  IGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYK 270

Query: 2243 KDKTKIH-VMPDTPDIL---QAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKA 2298
            KD   +H  + D P++L      +   + S + YK  +EE  K  Y    DA+     K 
Sbjct: 271  KDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEEN-KGMYHFDADAVEHLHHKG 329

Query: 2299 SRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFS 2358
            +  + S  KYK+ Y K  G  +      + P    S    KMQSE+ YK+DFEK + K  
Sbjct: 330  NAVLQSQVKYKEEYEKNKGKPM--LEFVETPSYQASKEAQKMQSEKVYKEDFEK-EIKGR 386

Query: 2359 SPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLE- 2417
            S +D+       K  E         +LH              K +  L  E  YK DLE 
Sbjct: 387  SSLDL------DKTPE---------FLH-------------VKYITNLLREKEYKKDLEN 418

Query: 2418 WLRGIGWSPLGS--LEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNR 2475
             ++G G   L S  L+ ++ KRASE+ SEK+Y++           D   I+  K      
Sbjct: 419  EIKGKGME-LNSEVLDIQRAKRASEMASEKEYKK-----------DLESIIKGKG----- 461

Query: 2476 SDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYE-ELKRKGYDLPVDAI 2534
                           +    DT ++  AK      S+K Y+   E E+K KG  +  D +
Sbjct: 462  ---------------MQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTL 506

Query: 2535 PIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFE 2594
             ++ AK + E+AS+ +YK+    ++    G +   D P ++ +   ++I S R+YK + E
Sbjct: 507  DVQRAKKASEMASQKQYKKDLENEIKGK-GMQVSMDIPDILRAKRTSEIYSQRKYKDEAE 565

Query: 2595 KWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNL 2654
            K  + +S+  D   +   K  Q  +S V YK  +   T + D  ++   ++     S   
Sbjct: 566  KMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVK 625

Query: 2655 YKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLAKNN 2714
            YK +++    I    S   E ++ K   + +S+  Y++    +K + +  +  +   + N
Sbjct: 626  YKEEIKHATAI----SDPPELKRVKENQKNISNLQYKE--QNYKATPVSMTPEIERVRRN 679

Query: 2715 AITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRV 2774
               ++   Y     +       + D PE+  AK+N+ N S   Y+  L  A        +
Sbjct: 680  QEQLSAVKYKGELQRGTA----ISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEM 735

Query: 2775 DAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKK 2834
            + +     K +++  S  KY + +++  G       I D P M          S  +Y +
Sbjct: 736  ERV-----KKNQENISSVKYTQDHKQMKGR---PSLILDTPAMRHVKEAQNHISMVKYHE 787

Query: 2835 DFEKWKTK-FSSPVDMLGVVLAKKCQTLVSDVDYK 2868
            DFEK K + F+  VD       +K   +VSD  YK
Sbjct: 788  DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822



 Score =  155 bits (392), Expect = 1e-36
 Identities = 170/699 (24%), Positives = 307/699 (43%), Gaps = 57/699 (8%)

Query: 32  YETTTTRTSDYEQSETSKPALAQPALAQPASAKPVERRKVIRK-----KVDPSKFMTPYI 86
           +++  +   D + + T    L +P +        +      +K       +P+    P  
Sbjct: 157 HQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDF 216

Query: 87  AHSQKMQDLFSPNKYKEKFE---KTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDV 143
            H+ +   L S  KYKEKF+   K K   Y +  ++   R+ +      S VKY+ D   
Sbjct: 217 EHAVEASKLSSQIKYKEKFDNEMKDKKHHY-NPLESASFRQNQLAATLASNVKYKKD--- 272

Query: 144 AKTICHVDEKAKD------IEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVK 197
              I ++ +   D      ++H  K S+ +S   YK+ +E+ K  Y    DA E +    
Sbjct: 273 ---IQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKG 329

Query: 198 NTAMFSKKLYTEDWEADKSL-FYPYNDSPELRRVAQAQKALSDVAYKKGLAEQ--QAQFT 254
           N  + S+  Y E++E +K      + ++P  +   +AQK  S+  YK+   ++       
Sbjct: 330 NAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSL 389

Query: 255 PLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSE--TPCFEVANARMNADNISTRKY 312
            L   P+    K +TN + +++YK+D EN+IKGK  E  +   ++  A+  ++  S ++Y
Sbjct: 390 DLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEY 449

Query: 313 QEDFEN-MKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKN-KGKADYNVLPASENP 370
           ++D E+ +K +     T+T E +  KKA   AS+  YK D E   KGK    +  +++  
Sbjct: 450 KKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGK---GMQVSTDTL 506

Query: 371 QLRQLKAAGDALSDKLYKENYE-KTKAKSINY-CETPKFKLDTVLQNFSSDKKYKDSYLK 428
            +++ K A +  S K YK++ E + K K +    + P            S +KYKD   K
Sbjct: 507 DVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEK 566

Query: 429 DILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQC 488
            +L +Y  +  D      +K T QN    +   Y+++ G G   +  + E E +KK +Q 
Sbjct: 567 -MLSNY-STIADTPEIQRIKTTQQNISAVF---YKKEVGAGTAVKD-SPEIERVKK-NQQ 619

Query: 489 KDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQ 548
              + K   +    T ++D P L + + N K +S+L YK     + +K      TP   +
Sbjct: 620 NISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQYK----EQNYKATPVSMTPEIER 675

Query: 549 HKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKM 608
            + N   LS   YK + ++  A       D   L  AK N KN S+V Y       +G++
Sbjct: 676 VRRNQEQLSAVKYKGELQRGTAIS-----DPPELKRAKENQKNISNVYY-------RGQL 723

Query: 609 IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKN-FSEA 667
               +++  P+M    K  +N S   Y +++++ K +     +TP  +   + +N  S  
Sbjct: 724 GRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMV 783

Query: 668 RYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYK 706
           +Y + + K     +   ++DP      K     SD +YK
Sbjct: 784 KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822



 Score =  153 bits (387), Expect = 5e-36
 Identities = 205/877 (23%), Positives = 351/877 (40%), Gaps = 106/877 (12%)

Query: 204  KKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIE 263
            +K+  E+ E D+  + P  +   +    +  + +SD+ YK+   + + + T + D P + 
Sbjct: 16   EKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLN 75

Query: 264  FAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQI 323
              K +   +S+ KYK                       + AD             + + +
Sbjct: 76   HVKNIGAFISEAKYK---------------------GTIKAD-------------LSNSL 101

Query: 324  YFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALS 383
            Y     T +     +     S+V YK+ ++  KG +DY  +   E P+++         S
Sbjct: 102  YKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHM--KEPPEVKHAMEVNKHQS 159

Query: 384  DKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYH 443
            +  Y+++ + T   S    + P  K+ T +    S+ +YK    + I+         P  
Sbjct: 160  NISYRKDVQDTHTYSAE-LDRPDIKMATQISKIISNAEYKKG--QGIMNKEPAVIGRPDF 216

Query: 444  SHCMKVTAQNSDKNYKAEYE-EDRGKGFFPQTITQEYEAIKKLDQCKDHTYKVHPD-KTK 501
             H ++ +  +S   YK +++ E + K      +        +L        K   D +  
Sbjct: 217  EHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNM 276

Query: 502  FTQVTDSPVLL---QAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSD 558
               V+D P LL        SK LS   YK   E  K   H   D    + HK NA   S 
Sbjct: 277  HDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQ 336

Query: 559  NLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKN-KGKMIGVLSINDD 617
              YK+++EK+K K     V+     A+K   K  S+ +YK+D+EK  KG+    L ++  
Sbjct: 337  VKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGR--SSLDLDKT 394

Query: 618  PKMLHSLKVAKNQSDRLYKENYE-KTKAKSMNYCETPKYQLDTQ-LKNFSEARYKDLYVK 675
            P+ LH   +     ++ YK++ E + K K M   E     LD Q  K  SE   +  Y K
Sbjct: 395  PEFLHVKYITNLLREKEYKKDLENEIKGKGM---ELNSEVLDIQRAKRASEMASEKEYKK 451

Query: 676  DVLGHYVG-SMEDPYHT----HCMKVAAQNSDKSYKAEYE-EDKGKCYFPQTITQEYEAI 729
            D+     G  M+    T    H  K A   S+K YK + E E KGK     T T + +  
Sbjct: 452  DLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRA 511

Query: 730  KKL-DQCKDHTYKVHPD---KTKFTAVT-DSPVLLQAQLNTKQLSDLNYKAKHEGEKFKC 784
            KK  +      YK   +   K K   V+ D P +L+A+  ++  S   YK + E      
Sbjct: 512  KKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNY 571

Query: 785  HIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMY 844
               AD P+  + +    N+S   YK++     A K   +++ +     K N +N S V Y
Sbjct: 572  STIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERV-----KKNQQNISSVKY 626

Query: 845  KKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIY----------- 893
            K++ +        A +I+D P++    +  KN S+ +Y++   K+  +            
Sbjct: 627  KEEIKH-------ATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRN 679

Query: 894  ----------------TAPLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAK 937
                            TA  D  ++ +AK++Q   S+V Y+  L   +    +  ++  K
Sbjct: 680  QEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTPEMERVK 739

Query: 938  KAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLK---FT 994
            K     S V+Y  D+   MKG   +   +  M   K A + ++  KY +  +  K   FT
Sbjct: 740  KNQENISSVKYTQDHKQ-MKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFT 798

Query: 995  SIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLP 1031
             + D P+T + + N    SD AYK     I+     P
Sbjct: 799  PVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRP 835



 Score =  149 bits (375), Expect = 1e-34
 Identities = 183/805 (22%), Positives = 325/805 (40%), Gaps = 100/805 (12%)

Query: 4288 YKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYR--------NYLHQWMCHPDQNDV 4339
            YKE++ K+K K     D   +   K     +S+  Y+        N L++ M  P   D 
Sbjct: 54   YKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRM--PATIDS 111

Query: 4340 IQARKAYDLQSDNVYRADLEWLRGIGWI-----PLDSVDHVRVTKNQEMMSQIKYKKNAL 4394
            + A +   LQS+  Y+   +  +G         P +    + V K+Q   S I Y+K+  
Sbjct: 112  VFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQ---SNISYRKDVQ 168

Query: 4395 ENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDT---PHISHSKDMG 4451
            + +  + + +D P+I +A   S   S+ +YK    K +G     P     P   H+ +  
Sbjct: 169  DTH-TYSAELDRPDIKMATQISKIISNAEYK----KGQGIMNKEPAVIGRPDFEHAVEAS 223

Query: 4452 KLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKH-----ADLVNSELKYKETYEKQKGHY 4506
            KL S I YK  ++            Y P+  A       A  + S +KYK+  +      
Sbjct: 224  KLSSQIKYKEKFDNEMK---DKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDP- 279

Query: 4507 LAGKVIGEFPGVV---HCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYIL 4563
                 + + P ++   H L   KM S   Y+K +E+ K   H   D + H+  K    + 
Sbjct: 280  -----VSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQ 334

Query: 4564 SDLEYRHYFHQ-----WTSLLEEPNVIRVRNAQEILSDNVYKDDLNW-LKGIGCYVWD-T 4616
            S ++Y+  + +         +E P+    + AQ++ S+ VYK+D    +KG      D T
Sbjct: 335  SQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKT 394

Query: 4617 PQILHAKKSYDLQSQLQYTAAGKENLQN------YNLVTDTPLYVTAVQSGINASEVKYK 4670
            P+ LH K   +L  + +Y    K++L+N        L ++      A ++   ASE +YK
Sbjct: 395  PEFLHVKYITNLLREKEY----KKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYK 450

Query: 4671 ENYHQI-KDKYTTV-LETVDYDRTRNLKNLYSSNLYKEAWD-RVKATSYILPSSTLSLTH 4727
            ++   I K K      +T++    +    + S   YK   +  +K     + + TL +  
Sbjct: 451  KDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQR 510

Query: 4728 AKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKM 4787
            AK    +AS  +Y+++ E       +  S+D  P+  R  R  ++   R Y+   EK   
Sbjct: 511  AKKASEMASQKQYKKDLENEIKGKGMQVSMDI-PDILRAKRTSEIYSQRKYKDEAEKMLS 569

Query: 4788 KIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDD 4847
                + D  E+   K +Q+ +S + Y+  +       D    + V+K    IS + YK++
Sbjct: 570  NYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEE 629

Query: 4848 LNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKT-------------RNDYKL-- 4892
            +     I     D PE+   K       +++YK    K              RN  +L  
Sbjct: 630  IKHATAIS----DPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSA 685

Query: 4893 ------------VTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALH 4940
                        ++D P   +A ++ K +S+  Y         G+    + T +++R   
Sbjct: 686  VKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL-----GRATTLSVTPEMERVKK 740

Query: 4941 AYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLG 5000
              +  SS  Y    + +     L  DTP  +H+K+ +   S  KY E +E TK  G+T  
Sbjct: 741  NQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPV 800

Query: 5001 PKDVPFVHVRRVNNVTSERLYRELY 5025
              D     VR+   V S+  Y+ ++
Sbjct: 801  VDDPVTERVRKNTQVVSDAAYKGVH 825



 Score =  147 bits (371), Expect = 3e-34
 Identities = 202/859 (23%), Positives = 368/859 (42%), Gaps = 124/859 (14%)

Query: 1412 YTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNERK 1471
            Y  + + +S+E  R   ++ SD  YK+E+        ++   S  +  VK  G  ++E K
Sbjct: 30   YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFV-TDSPMLNHVKNIGAFISEAK 88

Query: 1472 YRQHPDTVK-------FTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLK--HKYTIDPEL 1522
            Y+    T+K       +  +P ++  V A   T+  S++ YK + +  K    Y    E 
Sbjct: 89   YK---GTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEP 145

Query: 1523 PQFIQAKVNALNMSDAHYKADWKKTIAKGYDL-RPDAIPIVAAKSSRNIASDCKYKEAYE 1581
            P+   A     + S+  Y+ D + T     +L RPD   I  A     I S+ +YK    
Sbjct: 146  PEVKHAMEVNKHQSNISYRKDVQDTHTYSAELDRPD---IKMATQISKIISNAEYK---- 198

Query: 1582 KAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYE---ASKTKYHTPLDMVSVTAAK 1638
            K +G      ++   P   H +  +K+ S  +YK+ ++     K  ++ PL+  S    +
Sbjct: 199  KGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQ 258

Query: 1639 KSQEVATNANYRQSYHH----YTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWV 1694
             +  +A+N  Y++   +     + LP+ L ++H   A ++ S   YK  F    KG+   
Sbjct: 259  LAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEE-NKGMYHF 317

Query: 1695 PIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTME----QALNKSNKLNMDKRLYT 1750
              +++E    K    + S+ KY++  EK K    ++ +E    QA  ++ K+  +K +Y 
Sbjct: 318  DADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEK-VYK 376

Query: 1751 EKWNKD---KTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEE-KKKGYDLRPDAIAIK 1806
            E + K+   ++++  +  TP+ L  +     + +K YK   E E K KG +L  + + I+
Sbjct: 377  EDFEKEIKGRSSLD-LDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQ 435

Query: 1807 AARASRDIASDYKYKKAYEQ-AKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYE-- 1863
             A+ + ++AS+ +YKK  E   KGK  G ++  D  ++ H  + A++ S+++YK+  E  
Sbjct: 436  RAKRASEMASEKEYKKDLESIIKGK--GMQAGTDTLEMQHAKKAAEIASEKDYKRDLETE 493

Query: 1864 -KSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDN 1922
             K K       D L V  AKK+ E+A                               S  
Sbjct: 494  IKGK-GMQVSTDTLDVQRAKKASEMA-------------------------------SQK 521

Query: 1923 QYKADYADFMKGIGW-LPLGSLEAEKNKKAMEIISEKKYRQHPDTL--KYSTLMDSMNMV 1979
            QYK D  + +KG G  + +   +  + K+  EI S++KY+   + +   YST+ D+  + 
Sbjct: 522  QYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQ 581

Query: 1980 LAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKG 2039
              +   + ++   YK+   A       + D P+I   K N  N+S   YK  ++ +    
Sbjct: 582  RIKTTQQNISAVFYKKEVGAGTA----VKDSPEIERVKKNQQNISSVKYKEEIKHATAIS 637

Query: 2040 YDLRPDAIPIKAAKASRDIASDYKYK-YNYE-----------------------KGKGKM 2075
                 D   +K  K ++   S+ +YK  NY+                       K KG++
Sbjct: 638  -----DPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKGEL 692

Query: 2076 VGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANITNT 2135
                ++ D P+L  + +  K  S+  Y+       T   TP     +   K  Q NI++ 
Sbjct: 693  QRGTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTP----EMERVKKNQENISSV 748

Query: 2136 NY----KHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEV-E 2190
             Y    K +  +  L+ D   +   +      S  +Y +D+ E  KG G++P     V E
Sbjct: 749  KYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDF-EKTKGRGFTPVVDDPVTE 807

Query: 2191 KAKKATEYASDQKYR-QHP 2208
            + +K T+  SD  Y+  HP
Sbjct: 808  RVRKNTQVVSDAAYKGVHP 826



 Score =  146 bits (368), Expect = 8e-34
 Identities = 220/947 (23%), Positives = 389/947 (41%), Gaps = 148/947 (15%)

Query: 2674 EDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTT 2733
            ED K++   + + +       DQ  +  +++ + M LA+     ++   Y E + K K  
Sbjct: 7    EDIKDETEEEKIGEE--ENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDK 64

Query: 2734 VHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDA-IPIKAAKASRDIASEF 2792
               + D+P +   K      SE  YK  ++         R+ A I    A     + SE 
Sbjct: 65   CTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEV 124

Query: 2793 KYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGV 2852
             YK+ +    G    A  +++ P++  +M V K QS+  Y+KD +   T +S+ +D   +
Sbjct: 125  AYKQKHDAAKGFSDYAH-MKEPPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDI 182

Query: 2853 VLAKKCQTLVSDVDYKN---YLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIG 2909
             +A +   ++S+ +YK     +++   +  + D  HA +A  L S   YK          
Sbjct: 183  KMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKE--------- 233

Query: 2910 WVSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEA 2969
                        K   E+   K +  P +   F    + L   LA N             
Sbjct: 234  ------------KFDNEMKDKKHHYNPLESASFRQ--NQLAATLASN-----------VK 268

Query: 2970 WDKDKTQIHI-MPDTPEIMLARQNKINYSETL----YKLANEEAKKKGYDLRSDAIPIVA 3024
            + KD   +H  + D P ++    + +  S+ L    YK   EE K   Y   +DA+  + 
Sbjct: 269  YKKDIQNMHDPVSDLPNLLFL-DHVLKASKMLSGREYKKLFEENKGM-YHFDADAVEHLH 326

Query: 3025 AKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKT 3084
             K +  + S  KYK+ Y K  G  +      + P    S    K+QS++ YK+DFEK + 
Sbjct: 327  HKGNAVLQSQVKYKEEYEKNKGKPM--LEFVETPSYQASKEAQKMQSEKVYKEDFEK-EI 383

Query: 3085 KFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSD 3144
            K  S +D                            L    + +H +   +L  +  YK D
Sbjct: 384  KGRSSLD----------------------------LDKTPEFLHVKYITNLLREKEYKKD 415

Query: 3145 LQ-WLRGIGWVPIGS--MDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNA 3201
            L+  ++G G + + S  +D+ + KRA+E+ S+  Y++             LE ++ K   
Sbjct: 416  LENEIKGKG-MELNSEVLDIQRAKRASEMASEKEYKK------------DLESII-KGKG 461

Query: 3202 LNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAME-EAKKEGYDLRS 3260
            +                      DT E+  A++     SE  Y++ +E E K +G  + +
Sbjct: 462  MQAGT------------------DTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVST 503

Query: 3261 DAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKK 3320
            D + +  AK + ++AS  +YK+    ++    G +   D P I+ +   +++ S R+YK 
Sbjct: 504  DTLDVQRAKKASEMASQKQYKKDLENEIKGK-GMQVSMDIPDILRAKRTSEIYSQRKYKD 562

Query: 3321 DFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQS 3380
            + EK  + YS+  D   I   K  Q  +S V YK  +     + D  +I   +K     S
Sbjct: 563  EAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNIS 622

Query: 3381 DNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLA 3440
               YK +++    I     D  E+ R K   + +S+  Y++  +  K T ++ TPE    
Sbjct: 623  SVKYKEEIKHATAIS----DPPELKRVKENQKNISNLQYKE--QNYKATPVSMTPEIERV 676

Query: 3441 KNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYD 3500
            + N     ++L    +  + +    + D PE+  AK N+ N S+  Y+  L      G  
Sbjct: 677  RRN----QEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL------GRA 726

Query: 3501 LRLDAIP-IQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQ--- 3556
              L   P ++  K +++  S  KY + +++  G       I D P M    HV + Q   
Sbjct: 727  TTLSVTPEMERVKKNQENISSVKYTQDHKQMKGR---PSLILDTPAMR---HVKEAQNHI 780

Query: 3557 SDREYKKEFEKWKTKFSSPV--DMLGVVLAKKCQILVSDIDYK--HP 3599
            S  +Y ++FEK K +  +PV  D +   + K  Q+ VSD  YK  HP
Sbjct: 781  SMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV-VSDAAYKGVHP 826



 Score =  146 bits (368), Expect = 8e-34
 Identities = 192/859 (22%), Positives = 355/859 (41%), Gaps = 133/859 (15%)

Query: 3914 YTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINLARANALNVSNKLY 3973
            Y  +++   + LA+   E IS  +Y+E + K K     + D+P +N  +     +S   Y
Sbjct: 30   YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKY 89

Query: 3974 REGWD-EMKAGCDVRLDA-IPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDNKI 4031
            +     ++      R+ A I    A    ++ S+  YK  H+  KG +      ++  ++
Sbjct: 90   KGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG-FSDYAHMKEPPEV 148

Query: 4032 RWALIADKLQNEREYRLDWAK---WKAKIQSPVDMLSILHSKNSQALVSDMDYRN---YL 4085
            + A+  +K Q+   YR D      + A++  P   ++   SK    ++S+ +Y+     +
Sbjct: 149  KHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISK----IISNAEYKKGQGIM 204

Query: 4086 HQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWL---RGIGWMPNDSVSVNHAKHAADIF 4142
            ++   +  + D   A +A +L S   YK   +     +   + P +S S    + AA + 
Sbjct: 205  NKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLA 264

Query: 4143 SEKKYRTKIETLNFTPVD-------------------------------------DRVDY 4165
            S  KY+  I+ ++    D                                     D V++
Sbjct: 265  SNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEH 324

Query: 4166 VTAKQSGEILDDIKYRKDWNATKSKYTL--TETPLLHTAQEAARILDQYLYKEGWERQKA 4223
            +  K +  +   +KY++++   K K  L   ETP    ++EA ++  + +YKE +E++  
Sbjct: 325  LHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIK 384

Query: 4224 TGYILPPDAVP-FVHAHHCNDVQSELKYKAE---HVKQKGHYVGVPTMRDDPKLVWFEHA 4279
                L  D  P F+H  +  ++  E +YK +    +K KG  +    +     +   + A
Sbjct: 385  GRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVL----DIQRAKRA 440

Query: 4280 GQIQNERLYKEDYHKT-KAK-INIPADMVSVLAAKQGQTLVSDIDYRNYLHQ------WM 4331
             ++ +E+ YK+D     K K +    D + +  AK+   + S+ DY+  L          
Sbjct: 441  SEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQ 500

Query: 4332 CHPDQNDVIQARKAYDLQSDNVYRADLE-WLRGIGW-IPLDSVDHVRVTKNQEMMSQIKY 4389
               D  DV +A+KA ++ S   Y+ DLE  ++G G  + +D  D +R  +  E+ SQ KY
Sbjct: 501  VSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKY 560

Query: 4390 KKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKD 4449
            K  A +   N+ ++ D PEI   K    N S V YK    K  G  T   D+P I   K 
Sbjct: 561  KDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYK----KEVGAGTAVKDSPEIERVKK 616

Query: 4450 MGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAG 4509
              +  S++ YK                       KHA  ++   + K   E QK      
Sbjct: 617  NQQNISSVKYKEE--------------------IKHATAISDPPELKRVKENQKN----- 651

Query: 4510 KVIGEFPGVVHCLDFQKMRSALNYR-KHYEDTKANVHIPNDMMNHV-LAKRCQYILSDLE 4567
                               S L Y+ ++Y+ T      P  M   +   +R Q  LS ++
Sbjct: 652  ------------------ISNLQYKEQNYKAT------PVSMTPEIERVRRNQEQLSAVK 687

Query: 4568 YRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYD 4627
            Y+    + T++ + P + R +  Q+ +S+  Y+  L    G    +  TP++   KK+ +
Sbjct: 688  YKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL----GRATTLSVTPEMERVKKNQE 743

Query: 4628 LQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDK-YTTVLET 4686
              S ++YT   K+     +L+ DTP      ++  + S VKY E++ + K + +T V++ 
Sbjct: 744  NISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDD 803

Query: 4687 VDYDRTRNLKNLYSSNLYK 4705
               +R R    + S   YK
Sbjct: 804  PVTERVRKNTQVVSDAAYK 822



 Score =  137 bits (346), Expect = 3e-31
 Identities = 200/872 (22%), Positives = 370/872 (42%), Gaps = 98/872 (11%)

Query: 2341 QSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYL----HQWTCLPDQND 2396
            + E+  +++ E+ +  +   ++ L + LA+KC EL+SD+ YK        + T + D   
Sbjct: 14   EEEKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPM 73

Query: 2397 VVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKF 2456
            +   K +    SE  YK              G+++A+        +S   Y++       
Sbjct: 74   LNHVKNIGAFISEAKYK--------------GTIKAD--------LSNSLYKR------- 104

Query: 2457 TSIPDAMDIVLAKTNAKNRSDRLYREAWDKDK--TQIHIMPDTPDIVLAKANLINTSDKL 2514
              +P  +D V A    + +S+  Y++  D  K  +    M + P++  A     + S+  
Sbjct: 105  --MPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNIS 162

Query: 2515 YRMGYEELKRKGYDLPVDAIPIKAAKASREIAS--EYKYKEGFRKQLGHHIGARNIEDDP 2572
            YR   ++     Y   +D   IK A    +I S  EYK  +G   +    IG  + E   
Sbjct: 163  YRKDVQDTHT--YSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEH-- 218

Query: 2573 KMMWSMHVAKIQSDREYKKDFE---KWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLH 2629
                ++  +K+ S  +YK+ F+   K K    +P++       +   TL S+V YK  + 
Sbjct: 219  ----AVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQ 274

Query: 2630 QW----TCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQIL 2685
                  + LP+   + H  +A  + S   YK   +  KG+    + ++E   +K    + 
Sbjct: 275  NMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQ 334

Query: 2686 SDHVYRQHPDQFKFSSLMDSI--PMVLAKNNAITM-NHRLYTEAWDKD---KTTVHIMPD 2739
            S   Y++  ++ K   +++ +  P   A   A  M + ++Y E ++K+   ++++  +  
Sbjct: 335  SQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLD-LDK 393

Query: 2740 TPEVLLAKQNKVNYSEKLYKLGLE-EAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGY 2798
            TPE L  K       EK YK  LE E K KG ++  + + I+ AK + ++ASE +YK+  
Sbjct: 394  TPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDL 453

Query: 2799 RKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFE-KWKTK-FSSPVDMLGVVLAK 2856
               +    G +A  D  +M  +   A+I S+++YK+D E + K K      D L V  AK
Sbjct: 454  ESIIKGK-GMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAK 512

Query: 2857 KCQTLVSDVDYKNYLHQ------WTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGW 2910
            K   + S   YK  L             D  D++ A++  ++ S   YK + + M     
Sbjct: 513  KASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYS 572

Query: 2911 VSIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAW 2970
                + ++++ K   + +S   Y++  +    T+V DS E    K N  N++   Y E  
Sbjct: 573  TIADTPEIQRIKTTQQNISAVFYKK--EVGAGTAVKDSPEIERVKKNQQNISSVKYKEE- 629

Query: 2971 DKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRD 3030
             K  T I    D PE+   ++N+ N S   YK  N +A        S    I   + +++
Sbjct: 630  IKHATAI---SDPPELKRVKENQKNISNLQYKEQNYKATPV-----SMTPEIERVRRNQE 681

Query: 3031 VISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPV 3090
             +S  KYK   ++          I D P++  +    K  S+  Y+    +  T   +P 
Sbjct: 682  QLSAVKYKGELQR-------GTAISDPPELKRAKENQKNISNVYYRGQLGRATTLSVTP- 733

Query: 3091 DMLGVVLAKKCQTLVSDV----DYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQ 3146
                +   KK Q  +S V    D+K      + + D   + H ++A +  S   Y  D +
Sbjct: 734  ---EMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFE 790

Query: 3147 WLRGIGWVPIGSMDVV-KCKRAAEILSDNIYR 3177
              +G G+ P+    V  + ++  +++SD  Y+
Sbjct: 791  KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822


>gi|169217576 PREDICTED: similar to nebulin [Homo sapiens]
          Length = 410

 Score =  503 bits (1295), Expect = e-141
 Identities = 238/396 (60%), Positives = 312/396 (78%)

Query: 3472 IMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQL 3531
            ++ A +N +  S+KLY+    ++K++GYD+R DAI I+ AKASR+IAS+YKYKEGYRKQL
Sbjct: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 3532 GHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILV 3591
            GHH+G R ++DDPK +W+IH AKIQSDREYKK +EK K   ++P+DM+ +V AKKCQ+LV
Sbjct: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 3592 SDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVK 3651
            SDIDY++ LH+WTCLPDQNDVIQA+KAYDLQSD +YKSDLEWL+GIGW+P GSVEV +VK
Sbjct: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180

Query: 3652 RAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPD 3711
             A  +L++R YR   + LKFT I DTPE++ AK NA+ +S+ LY  AW+ +K +++V  D
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 3712 TPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYE 3771
            TP +L +K N+  IS K Y + W++ KM  YDLRADAI I+ AKASRDIASDY YK AYE
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 3772 KQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQ 3831
            KQKGH+IG +S ++DPK++ A +  K+Q++R YKK +   K K S PVDM+SI  AK+ Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 3832 TLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSD 3867
             L +D+DYR+YLH W+C PDQND+IQA+KAYDLQSD
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  501 bits (1291), Expect = e-141
 Identities = 240/396 (60%), Positives = 310/396 (78%), Gaps = 1/396 (0%)

Query: 3715 ILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQK 3774
            +L A  N+  IS KLY K W+++K K YD+RADAI IK AKASR+IAS+YKYKE Y KQ 
Sbjct: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 3775 GHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLV 3834
            GHH+G ++++DDPK + AIHA KIQS+REYKK ++K K   ++P+DM+SI+ AKKCQ LV
Sbjct: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 3835 TDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVK 3894
            +DIDYRNYLH+WTC+PDQND+IQAKKAYDLQSD LYK+DLEWL+GIGW+P+GS EV+RVK
Sbjct: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180

Query: 3895 NAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPD 3954
            NAQN+  + +YR     LK+TSIVDTPEV+ AK NA  IS P YR  W+K+K ++++  D
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 3955 TPEINLARANALNVSNKLYREGWDEMK-AGCDVRLDAIPIQAAKASREIASDYKYKLDHE 4013
            TP +  ++ NAL +SNK Y++ W+++K  G D+R DAI IQ AKASR+IASDY YK  +E
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 4014 KQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQ 4073
            KQKGHY+G  +A++D K+ WA    K+QN+R Y+  +   KAKI  PVDM+SI  +K  Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 4074 ALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSD 4109
            AL SD+DYR+YLH W+C PDQNDVIQA+KAY+LQSD
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  494 bits (1272), Expect = e-138
 Identities = 232/396 (58%), Positives = 303/396 (76%)

Query: 3229 IMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQL 3288
            ++ A  N +  S  LY++   + K++GYD+R+DAI I  AKASR+IAS+YKYKE YRKQL
Sbjct: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 3289 GHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLV 3348
            GHH+G R + DDPK +W++H AK+QSDREYKK +EK K  +++P+DM+ IV AKKCQ LV
Sbjct: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 3349 SDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAK 3408
            SD+DY++ LH+W CLPDQND+I A+KAYDLQSDNLYKSDLEW+KGIGW+P  S+EV+R K
Sbjct: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180

Query: 3409 RAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPD 3468
             A  LL++ +YR +PE LKFTSI DTPE + AK NA+ +++ LY  AW+ +K  ++V  D
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 3469 TPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYR 3528
            TP ++ +K+N +  S+K Y+ A E+ K  GYDLR DAI IQ AKASRDIASDY YK  Y 
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 3529 KQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQ 3588
            KQ GH+IG R+ K+DPK++W+ +V K+Q+DR YKK +   K K S PVDM+ +  AK+ Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 3589 ILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSD 3624
             L SD+DY+H LH W+C PDQNDVIQARKAYDLQSD
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  483 bits (1244), Expect = e-135
 Identities = 223/396 (56%), Positives = 301/396 (76%)

Query: 2986 IMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQL 3045
            ++ A  N +  S  LY+    + K+KGYD+R+DAI I  AKASR++ S+YKYK+GYRKQL
Sbjct: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 3046 GHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 3105
            GHH+G R ++DDPK +W++H AKIQSDREYKK +EK K   ++P+DM+ +V AKKCQ LV
Sbjct: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 3106 SDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCK 3165
            SD+DY+NYLH+WTCLPDQNDVI A++AYDLQSDN+YKSDL+WL+GIGW+P GS++V++ K
Sbjct: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180

Query: 3166 RAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPD 3225
             A  +L++ +YR  P+ LKFTS+ D+ E + AK NA+ +++ LY  AW+K+K  V++  D
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 3226 TPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYR 3285
            TP ++ ++ N +  S   Y+QA E+ K  GYDLR+DAI I  AKASRDIASDY YK AY 
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 3286 KQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQ 3345
            KQ GH+IG R+  +DPK++W+ ++ K+Q+DR YKK +  +K + S PVDM+ I  AK+ Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 3346 TLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSD 3381
             L SDVDY+H LH W C PDQND+I ARKAYDLQSD
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  478 bits (1231), Expect = e-134
 Identities = 223/393 (56%), Positives = 298/393 (75%)

Query: 2503 AKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHH 2562
            A  N +  S+KLY+  + + K+KGYD+  DAI IK AKASREIASEYKYKEG+RKQLGHH
Sbjct: 4    AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHH 63

Query: 2563 IGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDV 2622
            +G R ++DDPK +W++H AKIQSDREYKK +EK K   ++P+DM+ +V AKKCQ LVSD+
Sbjct: 64   MGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDI 123

Query: 2623 DYKNYLHQWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRAT 2682
            DY+NYLHQWTCLPDQ+DVI A++AYDLQSDNLYKSDL+WLKGIGW+  GS+E  + K A 
Sbjct: 124  DYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183

Query: 2683 QILSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPE 2742
             +L++ +YR  P+  KF+S++D+  ++ AK NA+ ++  LY  AW+K+K  V++  DTP 
Sbjct: 184  NLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPL 243

Query: 2743 VLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQL 2802
            +L +K N +  S K Y+   E+ K  GYD+R DAI I+ AKASRDIAS++ YK  Y KQ 
Sbjct: 244  MLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQK 303

Query: 2803 GHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 2862
            GH+IG R+ ++DPK++W+ +V K+Q+DR YKK +   K K S PVDM+ +  AK+ Q L 
Sbjct: 304  GHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALA 363

Query: 2863 SDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSD 2895
            SDVDY++YLH W+C PDQ+DVI AR+AYDLQSD
Sbjct: 364  SDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  478 bits (1230), Expect = e-134
 Identities = 222/396 (56%), Positives = 300/396 (75%)

Query: 2743 VLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQL 2802
            +L A  N +  S KLY+    + K+KGYD+R DAI IK AKASR+IASE+KYKEGYRKQL
Sbjct: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 2803 GHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 2862
            GHH+G R ++DDPK +W++H AKIQSDREYKK +EK K   ++P+DM+ +V AKKCQ LV
Sbjct: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 2863 SDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCK 2922
            SD+DY+NYLHQWTCLPDQ+DVI A++AYDLQSDN+YKSDL+W++GIGW+  GS++V + K
Sbjct: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180

Query: 2923 RATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPD 2982
             A  +L++++YR  P+  KFTS+ D+ E + AK NA+ +++ LY  AW+K+K  +++  D
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 2983 TPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYR 3042
            TP ++ ++ N +  S   Y+ A E+ K  GYDLR+DAI I  AKASRD+ SDY YK  Y 
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 3043 KQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQ 3102
            KQ GH+IG R+ ++DPK++W+ +V K+Q+DR YKK +   K K S PVDM+ +  AK+ Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 3103 TLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSD 3138
             L SDVDY++YLH W+C PDQNDVI AR+AYDLQSD
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  477 bits (1227), Expect = e-133
 Identities = 223/396 (56%), Positives = 300/396 (75%)

Query: 2257 ILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQL 2316
            +LQA  N    S KLY+  W +  +KGYD+  DAI ++ AKASR+IAS+YKYK+GYRKQL
Sbjct: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 2317 GHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELV 2376
            GHH+GFR+LQDDPK V +++ AK+QS+REYKK +EK K   ++P+DM+ +V AKKCQ LV
Sbjct: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 2377 SDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNK 2436
            SD+DY+NYLHQWTCLPDQNDV+QAKK Y+LQS+NLYKSDLEWL+GIGW P GS+E  + K
Sbjct: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180

Query: 2437 RASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPD 2496
             A  +++E+ YR  P+  KFTSI D  +++ AK NA   S+ LYR AW+K+K  +++  D
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 2497 TPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFR 2556
            TP ++ +K N +  S+K Y+  +E++K  GYDL  DAI I+ AKASR+IAS+Y YK  + 
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 2557 KQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQ 2616
            KQ GH+IG R+ ++DPK++W+ +V K+Q+DR YKK +   K K S PVDM+ +  AK+ Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 2617 TLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSD 2652
             L SDVDY++YLH W+C PDQ+DVI AR+AYDLQSD
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  420 bits (1079), Expect = e-116
 Identities = 206/393 (52%), Positives = 275/393 (69%), Gaps = 2/393 (0%)

Query: 3961 ARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHY 4019
            A  NAL +SNKLY++ W++ K  G D+R DAI I+ AKASREIAS+YKYK  + KQ GH+
Sbjct: 4    AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHH 63

Query: 4020 VGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDM 4079
            +G  T +DD K  WA+ A K+Q++REY+  + K K    +P+DM+SI+ +K  Q LVSD+
Sbjct: 64   MGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDI 123

Query: 4080 DYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAA 4139
            DYRNYLHQWTC+PDQNDVIQAKKAY+LQSDN+YK+DLEWL+GIGW+P  SV V   K+A 
Sbjct: 124  DYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183

Query: 4140 DIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTL-TETPL 4198
            ++ +E+ YR K E L FT + D  + + AK +   + +  YR  W   K+   +  +TPL
Sbjct: 184  NLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPL 243

Query: 4199 LHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQK 4258
            +  ++  A  +    Y++ WE  K TGY L  DA+   HA    D+ S+  YK  + KQK
Sbjct: 244  MLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQK 303

Query: 4259 GHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLV 4318
            GHY+G  + ++DPKLVW  +  ++QN+RLYK+ Y+  KAKI+IP DMVS+ AAK+GQ L 
Sbjct: 304  GHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALA 363

Query: 4319 SDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSD 4351
            SD+DYR+YLH W C PDQNDVIQARKAYDLQSD
Sbjct: 364  SDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  392 bits (1006), Expect = e-108
 Identities = 192/397 (48%), Positives = 269/397 (67%), Gaps = 1/397 (0%)

Query: 2013 IILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGK 2072
            ++ A  NA+ +S+KLY+    ++K+KGYD+R DAI IK AKASR+IAS+YKYK  Y K  
Sbjct: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 2073 GKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANI 2132
            G  +GFR+L+DDPK V ++  AK+QSDREYKK YE +K  ++TP DM+S+  AK  Q  +
Sbjct: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 2133 TNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKA 2192
            ++ +Y++ +H++  LPD  ++   +    +QSDN YK D  EW KG+GW P GS+EV + 
Sbjct: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRV 179

Query: 2193 KKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMP 2252
            K A    +++ YR  P   +F  + D+ +++ AK NA  +++ LY   W K+K  ++V  
Sbjct: 180  KNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA 239

Query: 2253 DTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGY 2312
            DTP +LQ+K N    S K Y+  WE+    GYDL  DAI +Q AKASRDIASDY YK  Y
Sbjct: 240  DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299

Query: 2313 RKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKC 2372
             KQ GH++G RS ++DPKLV + NV KMQ++R YKK +   K K S PVDM+ +  AK+ 
Sbjct: 300  EKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEG 359

Query: 2373 QELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSE 2409
            Q L SDVDY++YLH W+C PDQNDV+QA+K Y+LQS+
Sbjct: 360  QALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  380 bits (977), Expect = e-104
 Identities = 195/396 (49%), Positives = 262/396 (66%), Gaps = 1/396 (0%)

Query: 1526 IQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKG 1585
            +QA +NAL +S+  Y+ DW  T  KGYD+R DAI I  AK+SR IAS+ KYKE Y K  G
Sbjct: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61

Query: 1586 KQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQEVAT 1645
              +GF +LQDDPK V  ++ AKIQSDREYKK YE SK  ++TPLDM+S+  AKK Q + +
Sbjct: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121

Query: 1646 NANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKAK 1705
            + +YR   H +T LPD  +V  ++ A  +QSDNLYKSD   W+KGIGW+P  S+EV + K
Sbjct: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRVK 180

Query: 1706 KAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPD 1765
             A  +L+E+ YR  PE LKFT  +DT E    K N + + + LY   W K+K  ++V  D
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 1766 TPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYE 1825
            TP +L S++N + +S+K Y+  WE+ K  GYDLR DAI I+ A+ASRDIASDY YK AYE
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 1826 QAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQ 1885
            + KG +IG RS ++DPKLV    V KMQ+DR YKK Y   K     PVDM+S+ AAK+ Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 1886 EVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSD 1921
             +A++ +YR+ +H ++  PD      A+    +QSD
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  379 bits (972), Expect = e-104
 Identities = 195/396 (49%), Positives = 267/396 (67%), Gaps = 1/396 (0%)

Query: 1038 IQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKG 1097
            +QA +NA  IS  +Y+ D  D  +KGYD+R DAI I+ AKA+R+ AS+ +YK+ Y K  G
Sbjct: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61

Query: 1098 KMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVS 1157
              +GF++LQDDPK V  ++ AKIQSDREYKK YEK+K  +NTP DM ++V AKK Q +VS
Sbjct: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121

Query: 1158 NVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVK 1217
            +++Y++ LH +T LPD  D+  +K    +QSDN+YK D   W+KGIGW+P GS++V +VK
Sbjct: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180

Query: 1218 KAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPD 1277
             A + LNE+ YR  P+ LKFTSIVD+P ++QAK N  Q+S+ LY+   E  K    +  D
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 1278 LPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYE 1337
             P  LQ+K NA  IS+  Y++ W D+   G ++  DAI I  AKASR+IASDY YK AYE
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 1338 KSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQ 1397
            K KG ++G RS ++DPKLV   NV K+Q+DR YKK Y + K     P DMVSI+AAK  Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 1398 DVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSD 1433
             +A++V+Y+  LHH++  PD   +   R    +QSD
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  377 bits (967), Expect = e-103
 Identities = 186/397 (46%), Positives = 272/397 (68%), Gaps = 1/397 (0%)

Query: 1769 ILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAK 1828
            +L + +N + +S+KLY+  W + K+KGYD+R DAI IK A+ASR+IAS+YKYK+ Y +  
Sbjct: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 1829 GKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVA 1888
            G H+GFR+L+DDPK V  +  AK+QSDREYKK YEKSK   +TP+DM+S+V AKK Q + 
Sbjct: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 1889 TNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKN 1948
            ++ +YRN +H +  LPD      AK    +QSDN YK+D  +++KGIGWLP GS+E  + 
Sbjct: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRV 179

Query: 1949 KKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP 2008
            K A  +++E+ YR  P+ LK+++++D+  ++ A+ NA  ++E LY+ AWE +K  V++  
Sbjct: 180  KNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA 239

Query: 2009 DIPQIILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNY 2068
            D P ++ +K NA+ +S+K Y+ + E+ K  GYDLR DAI I+ AKASRDIASDY YK  Y
Sbjct: 240  DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299

Query: 2069 EKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDA 2128
            EK KG  +G RS ++DPKLV +  V KMQ+DR YKK Y + K     P DM+S++AAK+ 
Sbjct: 300  EKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEG 359

Query: 2129 QANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSD 2165
            QA  ++ +Y+H +H +   PD  ++   R    +QSD
Sbjct: 360  QALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  362 bits (929), Expect = 7e-99
 Identities = 188/396 (47%), Positives = 260/396 (65%), Gaps = 1/396 (0%)

Query: 1282 LQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKG 1341
            LQA  NA  IS+  Y++DW+D   KG ++  DAI I  AKASR IAS+YKYKE Y K  G
Sbjct: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61

Query: 1342 KHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVAT 1401
             H+GFR+LQDDPK V  ++ AK+QSDREYKK YE +K  ++TP DM+SI  AK  Q + +
Sbjct: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121

Query: 1402 NVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVK 1461
            +++Y+  LH +T LPD   +   +    +QSDN+YK +   +LKGIGW+P GS+EV +VK
Sbjct: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180

Query: 1462 KAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPE 1521
             A + LNER YR  P+ +KFTS+ D+  ++ A+ N  Q+S+  Y+   EK K    +  +
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 1522 LPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYE 1581
             P  +Q+K+NAL +S+  Y+  W+     GYDLR DAI I  AK+SR+IASD  YK AYE
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 1582 KAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQ 1641
            K KG  +G  S ++DPKLV   NV K+Q+DR YKK Y   K K   P+DMVS++AAK+ Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 1642 EVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSD 1677
             +A++ +YR   HH++  PD  +V  +R A  +QSD
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  355 bits (912), Expect = 6e-97
 Identities = 180/396 (45%), Positives = 257/396 (64%), Gaps = 1/396 (0%)

Query: 794  IQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKG 853
            +Q  +NA  +S+ +Y++DW  +K K +DI+ DAI +  AKA+ +  S+  YK+ Y K  G
Sbjct: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61

Query: 854  KMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIAS 913
              +G  ++ DDPK + ++  AK QSDREY+K YEKSK I+  PLDM+ + QAKK Q + S
Sbjct: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121

Query: 914  DVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAK 973
            D+DY++ LH ++  PD  +V  AKKAY LQSD  YK+D   W+KG GW+P GS+E+ + K
Sbjct: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180

Query: 974  RASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPD 1033
             A ++LNE+ YR  P+ LKFTSI D P  +Q+KIN  Q S+  Y+   E+     N+P D
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 1034 LPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYE 1093
             P  +Q+K+NA  IS   Y+   +D+   GYDLR DAI I+ AKA+R  ASD  YK  YE
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 1094 KAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQ 1153
            K KG  +G +S ++DPKLV   NV K+Q+DR YKK Y   K+K + P DM ++ AAK+ Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 1154 DVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSD 1189
             + S+V+Y+H LHH++  PD  D+  ++    +QSD
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  332 bits (850), Expect = 1e-89
 Identities = 174/386 (45%), Positives = 239/386 (61%), Gaps = 6/386 (1%)

Query: 4213 LYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPK 4272
            LY++ W   K  GY +  DA+   HA    ++ SE KYK  + KQ GH++G  T++DDPK
Sbjct: 15   LYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPK 74

Query: 4273 LVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMC 4332
             VW  HA +IQ++R YK+ Y K+K   N P DM+S++ AK+ Q LVSDIDYRNYLHQW C
Sbjct: 75   SVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTC 134

Query: 4333 HPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKNQEMMSQIKY--K 4390
             PDQNDVIQA+KAYDLQSDN+Y++DLEWL+GIGW+P  SV+ +RV   Q ++++  Y  K
Sbjct: 135  LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIK 194

Query: 4391 KNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDM 4450
              AL+    F S+VD PE++ AKIN+V  S+  Y+  + K K       DTP +  SK  
Sbjct: 195  PEALK----FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKIN 250

Query: 4451 GKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGK 4510
                S   Y+ AWE  K  GY L    I I  AK +  + S+  YK  YEKQKGHY+  +
Sbjct: 251  ALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCR 310

Query: 4511 VIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRH 4570
               E P +V   +  KM++   Y+K Y D KA + IP DM++   AK  Q + SD++YRH
Sbjct: 311  SAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYRH 370

Query: 4571 YFHQWTSLLEEPNVIRVRNAQEILSD 4596
            Y H W+   ++ +VI+ R A ++ SD
Sbjct: 371  YLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  261 bits (668), Expect = 1e-68
 Identities = 142/400 (35%), Positives = 222/400 (55%), Gaps = 4/400 (1%)

Query: 547 IQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKG 606
           +Q  +NA  +S+ LY++DW  +K K +DI+ DAI +  AKA+ +  S+  YK+ Y K  G
Sbjct: 2   LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61

Query: 607 KMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSE 666
             +G  ++ DDPK + ++  AK QSDR YK+ YEK+K        TP   +        +
Sbjct: 62  HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTPLDMMSIVQAKKCQ 117

Query: 667 ARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEY 726
               D+  ++ L  +    +        K     SD  YK++ E  KG  + P+   +  
Sbjct: 118 VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVM 177

Query: 727 EAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHI 786
                 +   +  Y++ P+  KFT++ D+P ++QA++N  Q+S+  Y+   E EK   ++
Sbjct: 178 RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNV 237

Query: 787 PADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKK 846
           PAD P  +Q ++NA  +S+  Y+Q WE  K   +D++ DAI +  AKA+    SD +YK 
Sbjct: 238 PADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKT 297

Query: 847 DYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAK 906
            YEK KG  IG  S  +DPK++ +    K Q+DR Y+K Y   K   + P+DM+ ++ AK
Sbjct: 298 AYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAK 357

Query: 907 KSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDV 946
           + QA+ASDVDY+H LH +S  PD  +V  A+KAY LQSDV
Sbjct: 358 EGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397



 Score =  241 bits (615), Expect = 2e-62
 Identities = 136/388 (35%), Positives = 205/388 (52%), Gaps = 2/388 (0%)

Query: 4455 STILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGE 4514
            S  LY+  W  TK  GY +    I I  AK +  + SE KYKE Y KQ GH++  + + +
Sbjct: 12   SNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQD 71

Query: 4515 FPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQ 4574
             P  V  +   K++S   Y+K YE +K   + P DMM+ V AK+CQ ++SD++YR+Y HQ
Sbjct: 72   DPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ 131

Query: 4575 WTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQY 4634
            WT L ++ +VI+ + A ++ SDN+YK DL WLKGIG     + +++  K + +L ++  Y
Sbjct: 132  WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLY 191

Query: 4635 TAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRN 4694
                K     +  + DTP  + A  + +  SE  Y+  + + K       +T    +++ 
Sbjct: 192  RI--KPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKI 249

Query: 4695 LKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLP 4754
                 S+  Y++AW+ VK T Y L +  + + HAK  + +AS   Y+  YEK K  Y   
Sbjct: 250  NALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGC 309

Query: 4755 RSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYR 4814
            RS  +DP       V K+  DRLY+  Y  +K KI I  DMV +  AK+ Q   S++DYR
Sbjct: 310  RSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYR 369

Query: 4815 LRLHEWICHPDLQVNDHVRKVTDQISDI 4842
              LH W C PD       RK  D  SD+
Sbjct: 370  HYLHHWSCFPDQNDVIQARKAYDLQSDV 397



 Score =  182 bits (461), Expect = 1e-44
 Identities = 124/403 (30%), Positives = 190/403 (47%), Gaps = 14/403 (3%)

Query: 4700 SSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDD 4759
            S+ LY++ W+  K   Y + +  + + HAK  + +AS  KY+E Y K    +   R++ D
Sbjct: 12   SNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQD 71

Query: 4760 DPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVP-DMVEMVTAKDSQKKVSEIDYRLRLH 4818
            DP +   +   K+  DR Y+  YEK+K  IH  P DM+ +V AK  Q  VS+IDYR  LH
Sbjct: 72   DPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH 130

Query: 4819 EWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIK 4878
            +W C PD       +K  D  SD +YK DL WLKGIG     + E++  K+A +L ++  
Sbjct: 131  QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERL 190

Query: 4879 Y--KAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLD 4936
            Y  K   LK    +  + DTP  +QA  +  Q+S+ +Y   +         P    + L 
Sbjct: 191  YRIKPEALK----FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQ 246

Query: 4937 RALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAY- 4995
              ++A ++ +    +       TGY L  D    +H K +R ++S + YK AYE  K + 
Sbjct: 247  SKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHY 306

Query: 4996 -GYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSEL 5054
             G     +D   V    V  + ++RLY++ Y+  K KI    D   I   K+ Q   S++
Sbjct: 307  IGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDV 366

Query: 5055 IYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQV 5097
             Y+        H    P    VI  R   D+ SD+      QV
Sbjct: 367  DYRHYLH----HWSCFPDQNDVIQARKAYDLQSDVSVSPRKQV 405



 Score =  177 bits (448), Expect = 4e-43
 Identities = 110/346 (31%), Positives = 175/346 (50%), Gaps = 6/346 (1%)

Query: 300 ARMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKA 359
           A +NA  IS + YQ+D+ + K + Y ++ +  E K  K +   AS+ KYKE Y K  G  
Sbjct: 4   AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH- 62

Query: 360 DYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSD 419
                   ++P+      A    SD+ YK+ YEK+K        TP   + +++Q     
Sbjct: 63  HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTP-LDMMSIVQAKKCQ 117

Query: 420 KKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEY 479
               D   ++ L  +    +        K     SD  YK++ E  +G G+ P+   +  
Sbjct: 118 VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVM 177

Query: 480 EAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHI 539
                 +   +  Y++ P+  KFT + D+P ++QA++N+ Q+S+  Y+   E EK   ++
Sbjct: 178 RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNV 237

Query: 540 PPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKK 599
           P DTP  +Q K+NA  +S+  Y+Q WE  K   +D++ DAI +  AKA+    SD +YK 
Sbjct: 238 PADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKT 297

Query: 600 DYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAK 645
            YEK KG  IG  S  +DPK++ +  V K Q+DRLYK+ Y   KAK
Sbjct: 298 AYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAK 343



 Score =  133 bits (335), Expect = 5e-30
 Identities = 119/409 (29%), Positives = 183/409 (44%), Gaps = 30/409 (7%)

Query: 4940 HAYKLQSSN-LYKTSLR-TLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGY 4997
            H   LQ SN LY+     T   GY +  D    KH K +R ++S +KYKE Y   K  G+
Sbjct: 5    HINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYR--KQLGH 62

Query: 4998 TLG-------PKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTP-DTPEIRQVKKTQE 5049
             +G       PK V  +H  ++    S+R Y++ Y K K  IH TP D   I Q KK Q 
Sbjct: 63   HMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKG-IHNTPLDMMSIVQAKKCQV 118

Query: 5050 AVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTP 5109
             VS++ Y++   +       LP    VI  +   D+ SD  YK DL+ LKG G     + 
Sbjct: 119  LVSDIDYRNYLHQWT----CLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSV 174

Query: 5110 DMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQK 5169
            +++R ++ + L +  LY  K   +  K+  ++DTPE  + +     +SE +YR A +K+K
Sbjct: 175  EVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEK 232

Query: 5170 SIFTSVPDTPDLLRAKRGQKLQSQYLYVEL-ATKERPHHHAGNQTTALKHAKDVKDMVSE 5228
            +      DTP +L++K      S   Y +     +   +        ++HAK  +D+ S+
Sbjct: 233  ANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASD 292

Query: 5229 KKYKIQYEKMKDKY---TPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALD 5285
              YK  YEK K  Y       + P L+ A       +D  YK+ +   K K     D + 
Sbjct: 293  YLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVS 352

Query: 5286 IVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDV 5334
            I   ++     S + Y+      L  W   PD+ +    R   D  SDV
Sbjct: 353  ISAAKEGQALASDVDYRH----YLHHWSCFPDQNDVIQARKAYDLQSDV 397



 Score =  126 bits (317), Expect = 6e-28
 Identities = 111/405 (27%), Positives = 164/405 (40%), Gaps = 86/405 (21%)

Query: 5216 LKHAKDVKDMVSEKKYKIQYEKMKDK---YTPVPDTPILIRAKRAYWNASDLRYKETFQK 5272
            +KHAK  +++ SE KYK  Y K       +  + D P  + A  A    SD  YK+ ++K
Sbjct: 37   IKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 96

Query: 5273 TKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVS 5332
            +KG ++T  D + IV  +K    +S I Y+ NY+ Q   W  +PD+ +    +   D  S
Sbjct: 97   SKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYLHQ---WTCLPDQNDVIQAKKAYDLQS 152

Query: 5333 DVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINR 5392
            D  YK DL WLKGIG     + +                                     
Sbjct: 153  DNLYKSDLEWLKGIGWLPEGSVEVM----------------------------------- 177

Query: 5393 HFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKF 5452
              K A  L+NE+ YR   E  K  +  +VD P  + AK    QIS+  YR  +EK K   
Sbjct: 178  RVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANV 235

Query: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKY 5512
                DTP  L++     QIS+  Y+  +   K  GY    D   + H +  +D  SD  Y
Sbjct: 236  NVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLY 295

Query: 5513 KEVYQR--------------------------------------NKSNCTIEPDAVHIKA 5534
            K  Y++                                      +K+  +I  D V I A
Sbjct: 296  KTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISA 355

Query: 5535 AKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSD 5579
            AK+   + +++DY+        HW   PD+ D +QA K+   QSD
Sbjct: 356  AKEGQALASDVDYRHYLH----HWSCFPDQNDVIQARKAYDLQSD 396



 Score =  101 bits (252), Expect = 2e-20
 Identities = 102/381 (26%), Positives = 175/381 (45%), Gaps = 30/381 (7%)

Query: 5856 LNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPML 5915
            +N  Q+++    K   +  +  Y    D +E  H K + E+ S  KYKE Y K+ G  M 
Sbjct: 6    INALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHM- 64

Query: 5916 DFET----PTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASE 5971
             F T    P  + A  + ++QS +EY+K YE+S KG + T L++  +++  K    + S+
Sbjct: 65   GFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKS-KGIHNTPLDMM-SIVQAKKCQVLVSD 122

Query: 5972 KEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANET 6031
             +YR  L +       T + D  D+++AK A  + ++  YK DLE     +G+  +   +
Sbjct: 123  IDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWL---KGIGWLPEGS 173

Query: 6032 PDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKS 6091
             + MR +NA ++ ++  Y+   E  K  FTS+VDTPE+I A+      S+  Y+   EK 
Sbjct: 174  VEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKE 231

Query: 6092 MSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSK-GKITVVQDTPEILRVKENQKNFS 6150
             +      DTP + + + N    S  +YQ   ++ K     +  D   I   K ++   S
Sbjct: 232  KANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIAS 291

Query: 6151 SVLYKE--DVSPGTAIG-----KTPEMM----RVKQTQDHISSVKYKEAIGQGTPIPDLP 6199
              LYK   +   G  IG     + P+++     +K   D +    Y +   + +   D+ 
Sbjct: 292  DYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMV 351

Query: 6200 EVKRVKETQKHISSVMYKENL 6220
             +   KE Q   S V Y+  L
Sbjct: 352  SISAAKEGQALASDVDYRHYL 372



 Score = 95.5 bits (236), Expect = 2e-18
 Identities = 91/376 (24%), Positives = 173/376 (46%), Gaps = 28/376 (7%)

Query: 5470 QISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSN----CTI 5525
            QIS+ LY+ ++N  K +GY    D   + H +  ++  S+ KYKE Y++   +     T+
Sbjct: 10   QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69

Query: 5526 EPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLD 5585
            + D   + A   A K+ ++ +YKK YE +K       D    +QA K  +  SD +Y   
Sbjct: 70   QDDPKSVWAI-HAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY--- 125

Query: 5586 REFLKGCKLSVTDDKNTVLALRNTL-IESDLKYKEKHVKERGTCHAVPDTPQILLAKTVS 5644
            R +L   + +   D+N V+  +    ++SD  YK      +G       + +++  K   
Sbjct: 126  RNYLH--QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183

Query: 5645 NLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSI 5704
            NL++E  Y+  +K    +  +T++ +T + +  K     +S+  Y+  +  EK K+N ++
Sbjct: 184  NLLNERLYR--IKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAW--EKEKANVNV 237

Query: 5705 MLEPPEVK----HAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEY 5760
              + P +     +A++++ K+   A+ +D K    Y   AD   I+ A  +   AS+  Y
Sbjct: 238  PADTPLMLQSKINALQISNKRYQQAW-EDVKMT-GYDLRADAIGIQHAKASRDIASDYLY 295

Query: 5761 RAKHRKEGSHGL---SMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLY 5817
            +  + K+  H +   S    P +  A    K+ +   Y++ ++  K K     P D    
Sbjct: 296  KTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKIS--IPVDMVSI 353

Query: 5818 KVMKDANNLASEVKYK 5833
               K+   LAS+V Y+
Sbjct: 354  SAAKEGQALASDVDYR 369



 Score = 91.7 bits (226), Expect = 2e-17
 Identities = 105/408 (25%), Positives = 171/408 (41%), Gaps = 29/408 (7%)

Query: 5397 ATQLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK---F 5452
            A Q+ N K Y+ D+   K K Y +  D      AK + +  S+ KY++ Y K       F
Sbjct: 8    ALQISN-KLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGF 66

Query: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPM----LLHVRKVKDEVS 5508
             ++ D P+ +      K  SD  YK  Y K+K      IH+TP+    ++  +K +  VS
Sbjct: 67   RTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-----GIHNTPLDMMSIVQAKKCQVLVS 121

Query: 5509 DLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPD-RPDF 5567
            D+ Y+    +     T  PD   +  AK AY + ++  YK   E  K    W P+   + 
Sbjct: 122  DIDYRNYLHQ----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-IGWLPEGSVEV 176

Query: 5568 LQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGT 5627
            ++   +    ++  Y++  E LK    S+ D    + A  N +  S+  Y+    KE+  
Sbjct: 177  MRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKAN 234

Query: 5628 CHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT 5687
             +   DTP +L +K ++ L   NK      + +    Y    +     H K      SD 
Sbjct: 235  VNVPADTPLMLQSK-INALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDY 293

Query: 5688 NYKKKFVKEKGK-SNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTV-ADRPDI 5745
             YK  + K+KG         E P++  A  V K Q+D  Y+K   ++    ++  D   I
Sbjct: 294  LYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSI 353

Query: 5746 KKATQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQV 5793
              A +    AS+V+YR        H      + D+  A+KA  L S V
Sbjct: 354  SAAKEGQALASDVDYRHYLH----HWSCFPDQNDVIQARKAYDLQSDV 397



 Score = 91.7 bits (226), Expect = 2e-17
 Identities = 84/315 (26%), Positives = 143/315 (45%), Gaps = 11/315 (3%)

Query: 86  IAHSQKMQDLFSPNKYKEKFEKTKGQPYASTT---DTPELRRIKKVQDQLSEVKYRMDGD 142
           I H++  +++ S  KYKE + K  G      T   D   +  I   + Q S+ +Y+   +
Sbjct: 37  IKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ-SDREYKKAYE 95

Query: 143 VAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMF 202
            +K I +       I  AKK    VS + Y+        ++   PD  +++QA K   + 
Sbjct: 96  KSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQ 151

Query: 203 SKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDI 262
           S  LY  D E  K + +    S E+ RV  AQ  L++  Y+  +  +  +FT + D P++
Sbjct: 152 SDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEV 209

Query: 263 EFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQ 322
             AK    Q+S+  Y+  +E +            +  +++NA  IS ++YQ+ +E++K  
Sbjct: 210 IQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMT 269

Query: 323 IYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDAL 382
            Y ++ +    +  K +   AS   YK  YEK KG        A E+P+L          
Sbjct: 270 GYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHY-IGCRSAKEDPKLVWAANVLKMQ 328

Query: 383 SDKLYKENYEKTKAK 397
           +D+LYK+ Y   KAK
Sbjct: 329 NDRLYKKAYNDHKAK 343



 Score = 84.3 bits (207), Expect = 4e-15
 Identities = 95/414 (22%), Positives = 167/414 (40%), Gaps = 53/414 (12%)

Query: 5532 IKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKG 5591
            ++A  +A +++  L  K   +  +  +    D  +   A  S    S+++YK       G
Sbjct: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61

Query: 5592 CKL---SVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVS 5648
              +   ++ DD  +V A+    I+SD +YK+ + K +G  +   D   I+ AK    LVS
Sbjct: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121

Query: 5649 ENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEP 5708
            +  Y++++ +      +T LP+  D +  K+     SD  YK      KG     I   P
Sbjct: 122  DIDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-----IGWLP 170

Query: 5709 PEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEG 5768
                  M V          K+A+  L+      +P+  K T                   
Sbjct: 171  EGSVEVMRV----------KNAQNLLNERLYRIKPEALKFT------------------- 201

Query: 5769 SHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLAS 5828
                S++  P++  AK  A   S+  YR  ++KEK       P D+ L    K      S
Sbjct: 202  ----SIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNV--PADTPLMLQSKINALQIS 255

Query: 5829 EVKYKADLKKLHKPVTDMKESLI-MNHVLNTSQLASSYQYKKKYEKSKGHY---HTIPDN 5884
              +Y+   + +     D++   I + H   +  +AS Y YK  YEK KGHY    +  ++
Sbjct: 256  NKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKED 315

Query: 5885 LEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYR 5938
             + +      ++Q+   YK+ Y   + K  +  +  +   AKE Q + S  +YR
Sbjct: 316  PKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYR 369



 Score = 79.0 bits (193), Expect = 2e-13
 Identities = 91/349 (26%), Positives = 140/349 (40%), Gaps = 53/349 (15%)

Query: 166 QVSKVLYKQNWEDTKDK-YLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSL-----FY 219
           Q+S  LY+++W DTK K Y +  DA E+  A  +  + S+  Y E +   K L     F 
Sbjct: 10  QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYR--KQLGHHMGFR 67

Query: 220 PYNDSPELRRVAQAQKALSDVAYKKGLAEQQA---------------------------- 251
              D P+      A K  SD  YKK   + +                             
Sbjct: 68  TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN 127

Query: 252 ---QFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKG-KWSETPCFEVANARMNADNI 307
              Q+T L D  D+  AKK  +  S   YK D E  +KG  W      EV   +   + +
Sbjct: 128 YLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVKNAQNLL 186

Query: 308 STRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPAS 367
           + R Y+   E +K   +    +TPE    K   V  S+  Y+  +EK K     NV   +
Sbjct: 187 NERLYRIKPEALK---FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKA----NVNVPA 239

Query: 368 ENPQLRQLKAAGDALSDKLYKENYEKTKAKSINY-CETPKFKLDTVLQNFSSDKKYKDSY 426
           + P + Q K     +S+K Y++ +E  K    +   +    +     ++ +SD  YK +Y
Sbjct: 240 DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299

Query: 427 LKDILGHYVG---SFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFP 472
            K   GHY+G   + EDP       V    +D+ YK  Y + + K   P
Sbjct: 300 EKQ-KGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIP 347



 Score = 68.9 bits (167), Expect = 2e-10
 Identities = 96/386 (24%), Positives = 156/386 (40%), Gaps = 32/386 (8%)

Query: 192 LVQAVKNTAMFSKKLYTEDWEADKSLFYPYN-DSPELRRVAQAQKALSDVAYKKGLAEQQ 250
           ++QA  N    S KLY +DW   K   Y    D+ E++    +++  S+  YK+G  +Q 
Sbjct: 1   MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 251 AQ---FTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETP-----CFEVANARM 302
                F  L D P   +A       S ++YK+ YE K KG    TP       +    ++
Sbjct: 61  GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYE-KSKG-IHNTPLDMMSIVQAKKCQV 118

Query: 303 NADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYN 362
              +I  R Y   +  + DQ   +Q         KKA    S   YK D E  KG     
Sbjct: 119 LVSDIDYRNYLHQWTCLPDQNDVIQA--------KKAYDLQSDNLYKSDLEWLKG---IG 167

Query: 363 VLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKY 422
            LP   + ++ ++K A + L+++LY+   E  K  SI   +TP+     +     S+  Y
Sbjct: 168 WLPEG-SVEVMRVKNAQNLLNERLYRIKPEALKFTSI--VDTPEVIQAKINAVQISEPLY 224

Query: 423 KDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAI 482
           ++++ K+     V + + P          Q S+K Y+  +E+ +  G+  +      +  
Sbjct: 225 RNAWEKEKANVNVPA-DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHA 283

Query: 483 K-KLDQCKDHTYKVHPDKTK-----FTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFK 536
           K   D   D+ YK   +K K          + P L+ A    K  +D  YK  +   K K
Sbjct: 284 KASRDIASDYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAK 343

Query: 537 CHIPPDTPAFIQHKVNAYNLSDNLYK 562
             IP D  +    K      SD  Y+
Sbjct: 344 ISIPVDMVSISAAKEGQALASDVDYR 369



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 52/226 (23%), Positives = 91/226 (40%), Gaps = 14/226 (6%)

Query: 6262 EMERVKRNQENFSSVLYKE--------NMGKGTPLAVTPEMERVKHNQENISSVLYKENV 6313
            E++  K ++E  S   YKE        +MG  T L   P+     H  +  S   YK+  
Sbjct: 36   EIKHAKASREIASEYKYKEGYRKQLGHHMGFRT-LQDDPKSVWAIHAAKIQSDREYKKAY 94

Query: 6314 GKATATPVTP----EMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVKRNQENFSSV 6369
             K+     TP     + + K+ Q  +S + Y+  L + T  P   ++ + K+  +  S  
Sbjct: 95   EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDN 154

Query: 6370 LYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQG-KAAYVLDTPEMRRVRE 6428
            LYK ++         PE        +N  ++L    +R + +  K   ++DTPE+ + + 
Sbjct: 155  LYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKI 214

Query: 6429 TQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYR 6474
                IS   Y   +EK K         P+  + K N    S+  Y+
Sbjct: 215  NAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQ 260



 Score = 34.7 bits (78), Expect = 3.3
 Identities = 37/162 (22%), Positives = 64/162 (39%), Gaps = 10/162 (6%)

Query: 83  TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGD 142
           TP +  S+      S  +Y++ +E  K   Y    D   ++  K  +D  S+  Y+   +
Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 143 VAKTI---CHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNT 199
             K     C   ++   +  A  V +  +  LYK+ + D K K  +P D   +  A +  
Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 200 AMFSK---KLYTEDWEADKSLFYPYNDSPELRRVAQAQKALS 238
           A+ S    + Y   W    S F   ND  + R+    Q  +S
Sbjct: 361 ALASDVDYRHYLHHW----SCFPDQNDVIQARKAYDLQSDVS 398


>gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]
          Length = 237

 Score =  253 bits (647), Expect = 3e-66
 Identities = 121/198 (61%), Positives = 151/198 (76%), Gaps = 12/198 (6%)

Query: 3495 KKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAK 3554
            K   YDL L  +P             YKYKEGYRKQLGHH+G R ++DDPK +W+IH AK
Sbjct: 9    KPHTYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAK 56

Query: 3555 IQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQ 3614
            IQSDREYKK +EK K   ++P+DM+ +V AKKCQ+LVSDIDY++ LH+WTCLPDQNDVIQ
Sbjct: 57   IQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQ 116

Query: 3615 ARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCI 3674
            A+KAYDLQSD +YKSDLEWL+GIGW+P GSVEV +VK A  +L++R YR   + LKFT I
Sbjct: 117  AKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI 176

Query: 3675 TDTPEIVLAKNNALTMSK 3692
             DTPE++ AK NA+ +S+
Sbjct: 177  VDTPEVIQAKINAVQISE 194



 Score =  249 bits (635), Expect = 8e-65
 Identities = 115/171 (67%), Positives = 143/171 (83%)

Query: 3764 YKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLS 3823
            YKYKE Y KQ GHH+G ++++DDPK + AIHA KIQS+REYKK ++K K   ++P+DM+S
Sbjct: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 3824 ILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWM 3883
            I+ AKKCQ LV+DIDYRNYLH+WTC+PDQND+IQAKKAYDLQSD LYK+DLEWL+GIGW+
Sbjct: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142

Query: 3884 PQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENIS 3934
            P+GS EV+RVKNAQN+  + +YR     LK+TSIVDTPEV+ AK NA  IS
Sbjct: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQIS 193



 Score =  248 bits (632), Expect = 2e-64
 Identities = 116/198 (58%), Positives = 148/198 (74%), Gaps = 12/198 (6%)

Query: 3252 KKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAK 3311
            K   YDL    +P             YKYKE YRKQLGHH+G R + DDPK +W++H AK
Sbjct: 9    KPHTYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAK 56

Query: 3312 VQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIH 3371
            +QSDREYKK +EK K  +++P+DM+ IV AKKCQ LVSD+DY++ LH+W CLPDQND+I 
Sbjct: 57   IQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQ 116

Query: 3372 ARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSI 3431
            A+KAYDLQSDNLYKSDLEW+KGIGW+P  S+EV+R K A  LL++ +YR +PE LKFTSI
Sbjct: 117  AKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI 176

Query: 3432 TDTPEQVLAKNNALNMNK 3449
             DTPE + AK NA+ +++
Sbjct: 177  VDTPEVIQAKINAVQISE 194



 Score =  245 bits (626), Expect = 9e-64
 Identities = 106/175 (60%), Positives = 145/175 (82%)

Query: 3032 ISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVD 3091
            +  YKYK+GYRKQLGHH+G R ++DDPK +W++H AKIQSDREYKK +EK K   ++P+D
Sbjct: 20   VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79

Query: 3092 MLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGI 3151
            M+ +V AKKCQ LVSD+DY+NYLH+WTCLPDQNDVI A++AYDLQSDN+YKSDL+WL+GI
Sbjct: 80   MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139

Query: 3152 GWVPIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNK 3206
            GW+P GS++V++ K A  +L++ +YR  P+ LKFTS+ D+ E + AK NA+ +++
Sbjct: 140  GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194



 Score =  237 bits (605), Expect = 3e-61
 Identities = 103/172 (59%), Positives = 142/172 (82%)

Query: 2792 FKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLG 2851
            +KYKEGYRKQLGHH+G R ++DDPK +W++H AKIQSDREYKK +EK K   ++P+DM+ 
Sbjct: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 2852 VVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWV 2911
            +V AKKCQ LVSD+DY+NYLHQWTCLPDQ+DVI A++AYDLQSDN+YKSDL+W++GIGW+
Sbjct: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142

Query: 2912 SIGSLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNK 2963
              GS++V + K A  +L++++YR  P+  KFTS+ D+ E + AK NA+ +++
Sbjct: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194



 Score =  236 bits (603), Expect = 4e-61
 Identities = 108/193 (55%), Positives = 146/193 (75%), Gaps = 12/193 (6%)

Query: 2527 YDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSD 2586
            YDL +  +P             YKYKEG+RKQLGHH+G R ++DDPK +W++H AKIQSD
Sbjct: 13   YDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60

Query: 2587 REYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQA 2646
            REYKK +EK K   ++P+DM+ +V AKKCQ LVSD+DY+NYLHQWTCLPDQ+DVI A++A
Sbjct: 61   REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKA 120

Query: 2647 YDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSI 2706
            YDLQSDNLYKSDL+WLKGIGW+  GS+E  + K A  +L++ +YR  P+  KF+S++D+ 
Sbjct: 121  YDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTP 180

Query: 2707 PMVLAKNNAITMN 2719
             ++ AK NA+ ++
Sbjct: 181  EVIQAKINAVQIS 193



 Score =  236 bits (602), Expect = 6e-61
 Identities = 108/172 (62%), Positives = 139/172 (80%)

Query: 2306 YKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLG 2365
            YKYK+GYRKQLGHH+GFR+LQDDPK V +++ AK+QS+REYKK +EK K   ++P+DM+ 
Sbjct: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 2366 VVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWS 2425
            +V AKKCQ LVSD+DY+NYLHQWTCLPDQNDV+QAKK Y+LQS+NLYKSDLEWL+GIGW 
Sbjct: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142

Query: 2426 PLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSD 2477
            P GS+E  + K A  +++E+ YR  P+  KFTSI D  +++ AK NA   S+
Sbjct: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194



 Score =  204 bits (518), Expect = 3e-51
 Identities = 102/184 (55%), Positives = 136/184 (73%), Gaps = 7/184 (3%)

Query: 4249 KYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSV 4308
            KYK  + KQ GH++G  T++DDPK VW  HA +IQ++R YK+ Y K+K   N P DM+S+
Sbjct: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83

Query: 4309 LAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIP 4368
            + AK+ Q LVSDIDYRNYLHQW C PDQNDVIQA+KAYDLQSDN+Y++DLEWL+GIGW+P
Sbjct: 84   VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143

Query: 4369 LDSVDHVRVTKNQEMMSQIKY--KKNALENYPNFRSVVDPPEIVLAKINSVNQSDV-KYK 4425
              SV+ +RV   Q ++++  Y  K  AL+    F S+VD PE++ AKIN+V  S+V K +
Sbjct: 144  EGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQISEVEKSR 199

Query: 4426 ETFN 4429
            + FN
Sbjct: 200  DNFN 203



 Score =  198 bits (504), Expect = 1e-49
 Identities = 92/178 (51%), Positives = 128/178 (71%)

Query: 4006 YKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLS 4065
            YKYK  + KQ GH++G  T +DD K  WA+ A K+Q++REY+  + K K    +P+DM+S
Sbjct: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 4066 ILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWM 4125
            I+ +K  Q LVSD+DYRNYLHQWTC+PDQNDVIQAKKAY+LQSDN+YK+DLEWL+GIGW+
Sbjct: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142

Query: 4126 PNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKD 4183
            P  SV V   K+A ++ +E+ YR K E L FT + D  + + AK +   + +++  +D
Sbjct: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200



 Score =  189 bits (481), Expect = 6e-47
 Identities = 93/184 (50%), Positives = 131/184 (71%), Gaps = 1/184 (0%)

Query: 1087 QYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNV 1146
            +YK+ Y K  G  +GF++LQDDPK V  ++ AKIQSDREYKK YEK+K  +NTP DM ++
Sbjct: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83

Query: 1147 VAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWI 1206
            V AKK Q +VS+++Y++ LH +T LPD  D+  +K    +QSDN+YK D   W+KGIGW+
Sbjct: 84   VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWL 142

Query: 1207 PIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGE 1266
            P GS++V +VK A + LNE+ YR  P+ LKFTSIVD+P ++QAK N  Q+S++       
Sbjct: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNF 202

Query: 1267 DVKH 1270
            +V+H
Sbjct: 203  NVRH 206



 Score =  176 bits (446), Expect = 7e-43
 Identities = 86/172 (50%), Positives = 118/172 (68%), Gaps = 1/172 (0%)

Query: 844  YKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVT 903
            YK+ Y K  G  +G  ++ DDPK + ++  AK QSDREY+K YEKSK I+  PLDM+ + 
Sbjct: 25   YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIV 84

Query: 904  QAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVP 963
            QAKK Q + SD+DY++ LH ++  PD  +V  AKKAY LQSD  YK+D   W+KG GW+P
Sbjct: 85   QAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLP 143

Query: 964  FGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDI 1015
             GS+E+ + K A ++LNE+ YR  P+ LKFTSI D P  +Q+KIN  Q S++
Sbjct: 144  EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195



 Score =  172 bits (437), Expect = 8e-42
 Identities = 85/185 (45%), Positives = 124/185 (67%), Gaps = 1/185 (0%)

Query: 1330 YKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVS 1389
            YKYKE Y K  G H+GFR+LQDDPK V  ++ AK+QSDREYKK YE +K  ++TP DM+S
Sbjct: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 1390 ITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGW 1449
            I  AK  Q + ++++Y+  LH +T LPD   +   +    +QSDN+YK +   +LKGIGW
Sbjct: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGW 141

Query: 1450 IPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEG 1509
            +P GS+EV +VK A + LNER YR  P+ +KFTS+ D+  ++ A+ N  Q+S++    + 
Sbjct: 142  LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDN 201

Query: 1510 EKLKH 1514
              ++H
Sbjct: 202  FNVRH 206



 Score =  167 bits (424), Expect = 2e-40
 Identities = 86/172 (50%), Positives = 114/172 (66%), Gaps = 1/172 (0%)

Query: 1575 KYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSV 1634
            KYKE Y K  G  +GF +LQDDPK V  ++ AKIQSDREYKK YE SK  ++TPLDM+S+
Sbjct: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83

Query: 1635 TAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWV 1694
              AKK Q + ++ +YR   H +T LPD  +V  ++ A  +QSDNLYKSD   W+KGIGW+
Sbjct: 84   VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWL 142

Query: 1695 PIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDK 1746
            P  S+EV + K A  +L+E+ YR  PE LKFT  +DT E    K N + + +
Sbjct: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194



 Score =  166 bits (421), Expect = 6e-40
 Identities = 80/173 (46%), Positives = 120/173 (69%), Gaps = 1/173 (0%)

Query: 1818 YKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLS 1877
            YKYK+ Y +  G H+GFR+L+DDPK V  +  AK+QSDREYKK YEKSK   +TP+DM+S
Sbjct: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 1878 VVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGW 1937
            +V AKK Q + ++ +YRN +H +  LPD      AK    +QSDN YK+D  +++KGIGW
Sbjct: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSD-LEWLKGIGW 141

Query: 1938 LPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNE 1990
            LP GS+E  + K A  +++E+ YR  P+ LK+++++D+  ++ A+ NA  ++E
Sbjct: 142  LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE 194



 Score =  148 bits (374), Expect = 2e-34
 Identities = 71/168 (42%), Positives = 107/168 (63%), Gaps = 1/168 (0%)

Query: 2062 YKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLS 2121
            YKYK  Y K  G  +GFR+L+DDPK V ++  AK+QSDREYKK YE +K  ++TP DM+S
Sbjct: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 2122 VTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGW 2181
            +  AK  Q  +++ +Y++ +H++  LPD  ++   +    +QSDN YK D  EW KG+GW
Sbjct: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGW 141

Query: 2182 SPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNA 2229
             P GS+EV + K A    +++ YR  P   +F  + D+ +++ AK NA
Sbjct: 142  LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINA 189



 Score =  129 bits (325), Expect = 7e-29
 Identities = 66/182 (36%), Positives = 109/182 (59%), Gaps = 3/182 (1%)

Query: 4494 KYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNH 4553
            KYKE Y KQ GH++  + + + P  V  +   K++S   Y+K YE +K   + P DMM+ 
Sbjct: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83

Query: 4554 VLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYV 4613
            V AK+CQ ++SD++YR+Y HQWT L ++ +VI+ + A ++ SDN+YK DL WLKGIG   
Sbjct: 84   VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143

Query: 4614 WDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEV-KYKEN 4672
              + +++  K + +L ++  Y    K     +  + DTP  + A  + +  SEV K ++N
Sbjct: 144  EGSVEVMRVKNAQNLLNERLYRI--KPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDN 201

Query: 4673 YH 4674
            ++
Sbjct: 202  FN 203



 Score =  107 bits (268), Expect = 3e-22
 Identities = 67/176 (38%), Positives = 95/176 (53%), Gaps = 8/176 (4%)

Query: 4739 KYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVP-DMVE 4797
            KY+E Y K    +   R++ DDP +   +   K+  DR Y+  YEK+K  IH  P DM+ 
Sbjct: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMS 82

Query: 4798 MVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCY 4857
            +V AK  Q  VS+IDYR  LH+W C PD       +K  D  SD +YK DL WLKGIG  
Sbjct: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142

Query: 4858 VWDTPEILHAKHAYDLRDDIKY--KAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSD 4911
               + E++  K+A +L ++  Y  K   LK    +  + DTP  +QA  +  Q+S+
Sbjct: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQISE 194



 Score = 81.6 bits (200), Expect = 2e-14
 Identities = 50/188 (26%), Positives = 88/188 (46%), Gaps = 9/188 (4%)

Query: 597 YKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQ 656
           YK+ Y K  G  +G  ++ DDPK + ++  AK QSDR YK+ YEK+K        TP   
Sbjct: 25  YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK----GIHNTPLDM 80

Query: 657 LDTQLKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKC 716
           +        +    D+  ++ L  +    +        K     SD  YK++ E  KG  
Sbjct: 81  MSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140

Query: 717 YFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDL----- 771
           + P+   +        +   +  Y++ P+  KFT++ D+P ++QA++N  Q+S++     
Sbjct: 141 WLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200

Query: 772 NYKAKHEG 779
           N+  +H G
Sbjct: 201 NFNVRHYG 208



 Score = 73.2 bits (178), Expect = 8e-12
 Identities = 58/185 (31%), Positives = 91/185 (49%), Gaps = 20/185 (10%)

Query: 4983 FKYKEAYEHTKAYGYTLG-------PKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTT 5035
            +KYKE Y   K  G+ +G       PK V  +H  ++    S+R Y++ Y K K  IH T
Sbjct: 23   YKYKEGYR--KQLGHHMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKG-IHNT 76

Query: 5036 P-DTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKED 5094
            P D   I Q KK Q  VS++ Y++   +       LP    VI  +   D+ SD  YK D
Sbjct: 77   PLDMMSIVQAKKCQVLVSDIDYRNYLHQWT----CLPDQNDVIQAKKAYDLQSDNLYKSD 132

Query: 5095 LQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKT 5154
            L+ LKG G     + +++R ++ + L +  LY  K   +  K+  ++DTPE  + +    
Sbjct: 133  LEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAV 190

Query: 5155 HLSEL 5159
             +SE+
Sbjct: 191  QISEV 195



 Score = 72.4 bits (176), Expect = 1e-11
 Identities = 66/230 (28%), Positives = 94/230 (40%), Gaps = 50/230 (21%)

Query: 5226 VSEKKYKIQYEKMKDK---YTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKD 5282
            V   KYK  Y K       +  + D P  + A  A    SD  YK+ ++K+KG ++T  D
Sbjct: 20   VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79

Query: 5283 ALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTW 5342
             + IV  +K    +S I Y+ NY+ Q   W  +PD+ +    +   D  SD  YK DL W
Sbjct: 80   MMSIVQAKKCQVLVSDIDYR-NYLHQ---WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEW 135

Query: 5343 LKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMN 5402
            LKGIG     + +                                       K A  L+N
Sbjct: 136  LKGIGWLPEGSVEV-----------------------------------MRVKNAQNLLN 160

Query: 5403 EKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKF 5452
            E+ YR   E    K+  +VD P  + AK    QIS++      EKS+D F
Sbjct: 161  ERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQISEV------EKSRDNF 202



 Score = 69.7 bits (169), Expect = 9e-11
 Identities = 63/231 (27%), Positives = 113/231 (48%), Gaps = 23/231 (9%)

Query: 5864 SYQYKKKYEKSKGH---YHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETP 5920
            SY+YK+ Y K  GH   + T+ D+ + +    A ++QS  +YK+ YEK +G      +  
Sbjct: 22   SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMM 81

Query: 5921 TYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEE 5980
            + + AK+ Q + S  +YR    +       T L     ++  K A  + S+  Y+ DL E
Sbjct: 82   SIVQAKKCQVLVSDIDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDL-E 134

Query: 5981 SIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLN-AMANETPDFMRAR- 6038
             ++G G    E + +++R KNA  +LNE+ Y+      +K   L      +TP+ ++A+ 
Sbjct: 135  WLKGIGWLP-EGSVEVMRVKNAQNLLNERLYR------IKPEALKFTSIVDTPEVIQAKI 187

Query: 6039 NATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQ--VKNLSSQKKYKED 6087
            NA  I+   K + +  +   ++ S +D  ++  AQQ  +  LS+   Y  D
Sbjct: 188  NAVQISEVEKSRDNFNVR--HYGSYLDQKQLGPAQQWELSELSAMWTYPSD 236



 Score = 60.5 bits (145), Expect = 6e-08
 Identities = 54/191 (28%), Positives = 88/191 (46%), Gaps = 26/191 (13%)

Query: 5470 QISDILYKLEYNK--AKPRGYTTIHDTPM---LLHVRKVKDEVSDLKYKEVYQRNKSNCT 5524
            ++    YK  Y K      G+ T+ D P     +H  K++   SD +YK+ Y+++K    
Sbjct: 19   EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKGIHN 75

Query: 5525 IEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKL 5584
               D + I  AK    + +++DY+         W   PD+ D +QA K+   QSD  YK 
Sbjct: 76   TPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKS 131

Query: 5585 DREFLKGC------KLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQIL 5638
            D E+LKG        + V   KN     +N L E   + K + +K      ++ DTP+++
Sbjct: 132  DLEWLKGIGWLPEGSVEVMRVKNA----QNLLNERLYRIKPEALK----FTSIVDTPEVI 183

Query: 5639 LAKTVSNLVSE 5649
             AK  +  +SE
Sbjct: 184  QAKINAVQISE 194



 Score = 58.9 bits (141), Expect = 2e-07
 Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 13/167 (7%)

Query: 5595 SVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKD 5654
            ++ DD  +V A+    I+SD +YK+ + K +G  +   D   I+ AK    LVS+  Y++
Sbjct: 41   TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN 100

Query: 5655 HVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHA 5714
            ++ +      +T LP+  D +  K+     SD  YK      KG     I   P      
Sbjct: 101  YLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-----IGWLPEGSVEV 149

Query: 5715 MEVAKKQSDVAYR--KDAKENLHYTTVADRPDIKKATQAAKQASEVE 5759
            M V   Q+ +  R  +   E L +T++ D P++ +A   A Q SEVE
Sbjct: 150  MRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196



 Score = 57.8 bits (138), Expect = 4e-07
 Identities = 45/189 (23%), Positives = 82/189 (43%), Gaps = 11/189 (5%)

Query: 347 KYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPK 406
           KYKE Y K  G          ++P+      A    SD+ YK+ YEK+K        TP 
Sbjct: 24  KYKEGYRKQLGH-HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTP- 77

Query: 407 FKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDR 466
             + +++Q         D   ++ L  +    +        K     SD  YK++ E  +
Sbjct: 78  LDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137

Query: 467 GKGFFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDL-- 524
           G G+ P+   +        +   +  Y++ P+  KFT + D+P ++QA++N+ Q+S++  
Sbjct: 138 GIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEK 197

Query: 525 ---NYKAKH 530
              N+  +H
Sbjct: 198 SRDNFNVRH 206



 Score = 57.8 bits (138), Expect = 4e-07
 Identities = 51/177 (28%), Positives = 84/177 (47%), Gaps = 15/177 (8%)

Query: 6048 KYKQSAEMEKAN---FTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEI 6104
            KYK+    +  +   F ++ D P+ + A     + S ++YK+  EKS   + T LD   I
Sbjct: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83

Query: 6105 QRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAI 6164
             + ++ Q    +L    D +N   + T + D  ++++ K+     S  LYK D+     I
Sbjct: 84   VQAKKCQ----VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139

Query: 6165 GKTP----EMMRVKQTQDHISSVKYK---EAIGQGTPIPDLPEVKRVKETQKHISSV 6214
            G  P    E+MRVK  Q+ ++   Y+   EA+ + T I D PEV + K     IS V
Sbjct: 140  GWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL-KFTSIVDTPEVIQAKINAVQISEV 195



 Score = 52.8 bits (125), Expect = 1e-05
 Identities = 51/183 (27%), Positives = 78/183 (42%), Gaps = 9/183 (4%)

Query: 5295 DISKIKYKENYMSQLGI---WRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAY 5351
            ++   KYKE Y  QLG    +R++ D P+           SD +YK+     KGI     
Sbjct: 19   EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78

Query: 5352 DTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYE 5411
            D      A+K + L S   Y+    +    +  + D       K A  L ++  Y++D E
Sbjct: 79   DMMSIVQAKKCQVLVSDIDYRNYLHQ----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134

Query: 5412 QRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQI 5471
              K    L       +  K A + +++  YR   E    KFTSIVDTPE ++      QI
Sbjct: 135  WLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQI 192

Query: 5472 SDI 5474
            S++
Sbjct: 193  SEV 195



 Score = 52.0 bits (123), Expect = 2e-05
 Identities = 42/165 (25%), Positives = 79/165 (47%), Gaps = 7/165 (4%)

Query: 5091 YKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQ 5150
            Y++ L    GF   L D P  V + H  K+ S+  Y     K +  +   LD     + +
Sbjct: 29   YRKQLGHHMGFRT-LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAK 87

Query: 5151 ELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAG 5210
            + +  +S++ YR         +T +PD  D+++AK+   LQS  LY       +      
Sbjct: 88   KCQVLVSDIDYR----NYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143

Query: 5211 NQTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAK 5255
              +  +   K+ +++++E+ Y+I+ E +  K+T + DTP +I+AK
Sbjct: 144  EGSVEVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAK 186



 Score = 51.2 bits (121), Expect = 3e-05
 Identities = 55/208 (26%), Positives = 95/208 (45%), Gaps = 15/208 (7%)

Query: 5547 YKKQYEANKAH---WKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTV 5603
            YK+ Y     H   ++   D P  + A  ++  QSD EYK   E  KG   +  D  + V
Sbjct: 25   YKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIV 84

Query: 5604 LALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQG 5663
             A +  ++ SD+ Y+  +   + TC  +PD   ++ AK   +L S+N YK  ++     G
Sbjct: 85   QAKKCQVLVSDIDYR--NYLHQWTC--LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140

Query: 5664 SYTTLPE-TRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQS 5722
                LPE + + + VK     +++  Y+ K    K    ++ +++ PEV  A   A + S
Sbjct: 141  ---WLPEGSVEVMRVKNAQNLLNERLYRIKPEALK----FTSIVDTPEVIQAKINAVQIS 193

Query: 5723 DVAYRKDAKENLHYTTVADRPDIKKATQ 5750
            +V   +D     HY +  D+  +  A Q
Sbjct: 194  EVEKSRDNFNVRHYGSYLDQKQLGPAQQ 221



 Score = 50.4 bits (119), Expect = 6e-05
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 10/187 (5%)

Query: 100 KYKEKFEKTKGQPYASTT---DTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKD 156
           KYKE + K  G      T   D   +  I   + Q S+ +Y+   + +K I +       
Sbjct: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ-SDREYKKAYEKSKGIHNTPLDMMS 82

Query: 157 IEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKS 216
           I  AKK    VS + Y+        ++   PD  +++QA K   + S  LY  D E  K 
Sbjct: 83  IVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138

Query: 217 LFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQK 276
           + +    S E+ RV  AQ  L++  Y+  +  +  +FT + D P++  AK    Q+S+ +
Sbjct: 139 IGWLPEGSVEVMRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVE 196

Query: 277 YKEDYEN 283
              D  N
Sbjct: 197 KSRDNFN 203



 Score = 50.1 bits (118), Expect = 8e-05
 Identities = 56/205 (27%), Positives = 82/205 (40%), Gaps = 43/205 (20%)

Query: 4860 DTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYV 4919
            D P+ + A HA  ++ D +YK    K++  +    D    VQA K    +SD  Y  +Y+
Sbjct: 44   DDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYL 102

Query: 4920 HSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYM 4979
            H  +    P     D+ +A  AY LQS NLYK+ L  L                      
Sbjct: 103  H--QWTCLPDQN--DVIQAKKAYDLQSDNLYKSDLEWL---------------------- 136

Query: 4980 SSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTP 5039
                         K  G+ L    V  + V+   N+ +ERLYR     LK    +  DTP
Sbjct: 137  -------------KGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTP 180

Query: 5040 EIRQVKKTQEAVSELIYKSDFFKMQ 5064
            E+ Q K     +SE+    D F ++
Sbjct: 181  EVIQAKINAVQISEVEKSRDNFNVR 205



 Score = 48.1 bits (113), Expect = 3e-04
 Identities = 48/175 (27%), Positives = 89/175 (50%), Gaps = 24/175 (13%)

Query: 972  AKRASDILNEKKYRQHPDTLKFTSIEDAPIT----VQSKINQAQRSDIAYKAKGEEIIHK 1027
            A  A+ I ++++Y++  +  K   I + P+     VQ+K  Q   SDI Y+      +H+
Sbjct: 51   AIHAAKIQSDREYKKAYEKSK--GIHNTPLDMMSIVQAKKCQVLVSDIDYR----NYLHQ 104

Query: 1028 YNLPPDLPQFIQAKVNAYNI-SENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDV 1086
            +   PD    IQAK  AY++ S+N+YK+DL+ L   G+ L   ++ +   K A+   ++ 
Sbjct: 105  WTCLPDQNDVIQAK-KAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNER 162

Query: 1087 QYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPH 1141
             Y     + K + + F S+ D P+++     AKI + +    + EK++  +N  H
Sbjct: 163  LY-----RIKPEALKFTSIVDTPEVIQ----AKINAVQ--ISEVEKSRDNFNVRH 206



 Score = 47.8 bits (112), Expect = 4e-04
 Identities = 45/184 (24%), Positives = 83/184 (45%), Gaps = 10/184 (5%)

Query: 5405 KYRADYEQRKDK---YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEH 5461
            KY+  Y ++      +  + D+P+ + A  A    S  +Y+K YEKSK    + +D    
Sbjct: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83

Query: 5462 LRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKS 5521
            ++  K    +SDI Y+   ++     +T + D   ++  +K  D  SD  YK   +  K 
Sbjct: 84   VQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138

Query: 5522 NCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFE 5581
               +   +V +   K+A  +     Y+ + EA K  +    D P+ +QA  +++Q S+ E
Sbjct: 139  IGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEVE 196

Query: 5582 YKLD 5585
               D
Sbjct: 197  KSRD 200



 Score = 47.0 bits (110), Expect = 6e-04
 Identities = 38/159 (23%), Positives = 72/159 (45%), Gaps = 7/159 (4%)

Query: 4615 DTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYH 4674
            D P+ + A  +  +QS  +Y  A +++   +N   D    V A +  +  S++ Y+   H
Sbjct: 44   DDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH 103

Query: 4675 QIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHL 4734
            Q    +T + +  D  + +   +L S NLYK   + +K   + LP  ++ +   KN ++L
Sbjct: 104  Q----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNL 158

Query: 4735 ASHIKYREEYE--KFKALYTLPRSVDDDPNTARCLRVGK 4771
             +   YR + E  KF ++   P  +    N  +   V K
Sbjct: 159  LNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEK 197



 Score = 47.0 bits (110), Expect = 6e-04
 Identities = 50/191 (26%), Positives = 77/191 (40%), Gaps = 48/191 (25%)

Query: 2161 RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM 2220
            +IQSD EYK+ Y E  KG+  +P   + + +AKK     SD  YR               
Sbjct: 56   KIQSDREYKKAY-EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN-------------- 100

Query: 2221 DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL 2280
                            Y   W         +PD  D++QAK+   L S  LYK   E   
Sbjct: 101  ----------------YLHQWT-------CLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137

Query: 2281 KKGYDLPVDAISVQLAKASRDIASD--YKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVA 2338
              G+ LP  ++ V   K ++++ ++  Y+ K    K       F S+ D P+++ +   A
Sbjct: 138  GIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK-------FTSIVDTPEVIQAKINA 189

Query: 2339 KMQSEREYKKD 2349
               SE E  +D
Sbjct: 190  VQISEVEKSRD 200



 Score = 46.6 bits (109), Expect = 8e-04
 Identities = 53/202 (26%), Positives = 83/202 (41%), Gaps = 9/202 (4%)

Query: 5716 EVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSML 5775
            EV   +    YRK    ++ + T+ D P    A  AAK  S+ EY+  + K      + L
Sbjct: 19   EVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPL 78

Query: 5776 GRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKAD 5835
                I  AKK   L S + YR N+  +    P  N          K A +L S+  YK+D
Sbjct: 79   DMMSIVQAKKCQVLVSDIDYR-NYLHQWTCLPDQNDVIQ-----AKKAYDLQSDNLYKSD 132

Query: 5836 LKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLK-EAT 5894
            L+ L       + S+ +  V N   L +   Y+ K E  K  + +I D  E +  K  A 
Sbjct: 133  LEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAV 190

Query: 5895 ELQSIVKYKEKYEKERGKPMLD 5916
            ++  + K ++ +        LD
Sbjct: 191  QISEVEKSRDNFNVRHYGSYLD 212



 Score = 45.8 bits (107), Expect = 0.001
 Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 8/145 (5%)

Query: 4180 YRKDWNATKSKYTLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAH 4239
            YRK         TL + P    A  AA+I     YK+ +E+ K   +  P D +  V A 
Sbjct: 29   YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGI-HNTPLDMMSIVQAK 87

Query: 4240 HCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKI 4299
             C  + S++ Y+  ++ Q   +  +P   D   ++  + A  +Q++ LYK D    K   
Sbjct: 88   KCQVLVSDIDYR-NYLHQ---WTCLPDQND---VIQAKKAYDLQSDNLYKSDLEWLKGIG 140

Query: 4300 NIPADMVSVLAAKQGQTLVSDIDYR 4324
             +P   V V+  K  Q L+++  YR
Sbjct: 141  WLPEGSVEVMRVKNAQNLLNERLYR 165



 Score = 44.3 bits (103), Expect = 0.004
 Identities = 42/158 (26%), Positives = 70/158 (44%), Gaps = 10/158 (6%)

Query: 1481 FTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHY 1540
            F ++ D    V A H  K  SD  YK   EK K  +    ++   +QAK   + +SD  Y
Sbjct: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98

Query: 1541 KADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLV 1600
                 +     +   PD   ++ AK + ++ SD  YK   E  KG  +G+L  +   +++
Sbjct: 99   -----RNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150

Query: 1601 HYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAK 1638
               N   + ++R Y+   EA   K+ + +D   V  AK
Sbjct: 151  RVKNAQNLLNERLYRIKPEA--LKFTSIVDTPEVIQAK 186



 Score = 43.5 bits (101), Expect = 0.007
 Identities = 35/106 (33%), Positives = 53/106 (50%), Gaps = 7/106 (6%)

Query: 1969 YSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP-DIPQIILAKANAINMSDKL 2027
            + TL D    V A + AKI ++  YK+A+E  K  +H  P D+  I+ AK   + +SD  
Sbjct: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMSIVQAKKCQVLVSDID 97

Query: 2028 YKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKG 2073
            Y+  L +     +   PD   +  AK + D+ SD  YK + E  KG
Sbjct: 98   YRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138



 Score = 42.0 bits (97), Expect = 0.020
 Identities = 46/217 (21%), Positives = 94/217 (43%), Gaps = 53/217 (24%)

Query: 1649 YRQSYHHY----TLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKA 1704
            YR+   H+    TL  D  +V  + +A +IQSD  YK  +    KGI   P++ + + +A
Sbjct: 29   YRKQLGHHMGFRTLQDDPKSV-WAIHAAKIQSDREYKKAYEK-SKGIHNTPLDMMSIVQA 86

Query: 1705 KKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMP 1764
            KK   ++S+  YR                               Y  +W         +P
Sbjct: 87   KKCQVLVSDIDYRN------------------------------YLHQWT-------CLP 109

Query: 1765 DTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAY 1824
            D  D++ ++      SD LYK+  E  K  G+ L   ++ +   + ++++ ++  Y+   
Sbjct: 110  DQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR--- 165

Query: 1825 EQAKGKHIGFRSLEDDPKL----VHFMQVAKMQSDRE 1857
               K + + F S+ D P++    ++ +Q+++++  R+
Sbjct: 166  --IKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200



 Score = 42.0 bits (97), Expect = 0.020
 Identities = 46/206 (22%), Positives = 84/206 (40%), Gaps = 48/206 (23%)

Query: 1900 YNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKK 1959
            +  L D      A +  +IQSD +YK  Y +  KGI   PL  +   + KK   ++S+  
Sbjct: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAY-EKSKGIHNTPLDMMSIVQAKKCQVLVSDID 97

Query: 1960 YRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKAN 2019
            YR                               Y   W         +PD   +I AK  
Sbjct: 98   YRN------------------------------YLHQWTC-------LPDQNDVIQAKKA 120

Query: 2020 AINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFR 2079
                SD LYK  LE  K  G+ L   ++ +   K ++++ ++  Y+      K + + F 
Sbjct: 121  YDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRI-----KPEALKFT 174

Query: 2080 SLEDDPKL----VHSMQVAKMQSDRE 2101
            S+ D P++    ++++Q+++++  R+
Sbjct: 175  SIVDTPEVIQAKINAVQISEVEKSRD 200



 Score = 41.6 bits (96), Expect = 0.027
 Identities = 42/154 (27%), Positives = 65/154 (42%), Gaps = 10/154 (6%)

Query: 6133 VQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTP----EMMRVKQTQDHISSVKYKEA 6188
            +QD P+ +      K  S   YK+       I  TP     +++ K+ Q  +S + Y+  
Sbjct: 42   LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY 101

Query: 6189 IGQGTPIPDLPEVKRVKETQKHISSVMYKENL----GTGIPTTVTPEIERVKRNQENFSS 6244
            + Q T +PD  +V + K+     S  +YK +L    G G     + E+ RVK  Q   + 
Sbjct: 102  LHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNE 161

Query: 6245 VLY--KENLGKGIPTPITPEMERVKRNQENFSSV 6276
             LY  K    K      TPE+ + K N    S V
Sbjct: 162  RLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 39/151 (25%), Positives = 63/151 (41%), Gaps = 6/151 (3%)

Query: 5647 VSENKYKDHVKKHLAQG-SYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIM 5705
            V   KYK+  +K L     + TL +   +V      K  SD  YKK + K KG  N    
Sbjct: 20   VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHN--TP 77

Query: 5706 LEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHR 5765
            L+   +  A +     SD+ YR    +   +T + D+ D+ +A +A    S+  Y++   
Sbjct: 78   LDMMSIVQAKKCQVLVSDIDYRNYLHQ---WTCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134

Query: 5766 KEGSHGLSMLGRPDIEMAKKAAKLSSQVKYR 5796
                 G    G  ++   K A  L ++  YR
Sbjct: 135  WLKGIGWLPEGSVEVMRVKNAQNLLNERLYR 165



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 32/123 (26%), Positives = 59/123 (47%), Gaps = 7/123 (5%)

Query: 5369 YKYKEVFERTKSD---FKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPR 5425
            YKYKE + +       F+ + D P +    +A ++ ++++Y+  YE+ K  ++  +D   
Sbjct: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 5426 HLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKP 5485
             + AK     +S I YR NY     ++T + D  + ++  K     SD LYK +    K 
Sbjct: 83   IVQAKKCQVLVSDIDYR-NY---LHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138

Query: 5486 RGY 5488
             G+
Sbjct: 139  IGW 141



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 16/151 (10%)

Query: 4388 KYK---KNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHI 4444
            KYK   +  L ++  FR++ D P+ V A   +  QSD +YK+ + K+KG +    D   I
Sbjct: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83

Query: 4445 SHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKG 4504
              +K    L S I Y+        + +T       ++ AK A  + S+  YK   E  KG
Sbjct: 84   VQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG 138

Query: 4505 HYLAGKVIGEFP-GVVHCLDFQKMRSALNYR 4534
                   IG  P G V  +  +  ++ LN R
Sbjct: 139  -------IGWLPEGSVEVMRVKNAQNLLNER 162



 Score = 39.3 bits (90), Expect = 0.13
 Identities = 34/117 (29%), Positives = 58/117 (49%), Gaps = 7/117 (5%)

Query: 2438 ASEIISEKKYRQPPDRNK--FTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMP 2495
            A++I S+++Y++  +++K    +  D M IV AK      SD  YR        Q   +P
Sbjct: 54   AAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLP 109

Query: 2496 DTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYK 2552
            D  D++ AK      SD LY+   E LK  G+ LP  ++ +   K ++ + +E  Y+
Sbjct: 110  DQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165



 Score = 38.9 bits (89), Expect = 0.17
 Identities = 54/207 (26%), Positives = 85/207 (41%), Gaps = 17/207 (8%)

Query: 993  FTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMY 1052
            F +++D P +V +      +SD  YK   E+    +N P D+   +QAK     +S+  Y
Sbjct: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98

Query: 1053 KADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLV 1112
            +  L       +    D   +  AK A    SD  YK D E  KG  +G+   +   +++
Sbjct: 99   RNYLHQ-----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150

Query: 1113 HYMNVAKIQSDREY--KKDYEKTKSKYNTPHDM---FNVVAAKKAQDVVSNVNYKH--SL 1165
               N   + ++R Y  K +  K  S  +TP  +    N V   + +    N N +H  S 
Sbjct: 151  RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210

Query: 1166 HHYTYLPDAMDLELSK--NMMQIQSDN 1190
                 L  A   ELS+   M    SDN
Sbjct: 211  LDQKQLGPAQQWELSELSAMWTYPSDN 237



 Score = 37.7 bits (86), Expect = 0.39
 Identities = 38/142 (26%), Positives = 59/142 (41%), Gaps = 8/142 (5%)

Query: 1237 FTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCY 1296
            F ++ D P  V A    K  SD  YK   E  K  +    D+   +QAK     +SD+ Y
Sbjct: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98

Query: 1297 KRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLV 1356
            +   H         L D   +  AK + ++ SD  YK   E  KG  +G+   +   +++
Sbjct: 99   RNYLHQW-----TCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGWLP-EGSVEVM 150

Query: 1357 HYMNVAKLQSDREYKKNYENTK 1378
               N   L ++R Y+   E  K
Sbjct: 151  RVKNAQNLLNERLYRIKPEALK 172



 Score = 37.4 bits (85), Expect = 0.50
 Identities = 56/207 (27%), Positives = 85/207 (41%), Gaps = 21/207 (10%)

Query: 716 CYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTK-----FTAVTDSPVLLQAQLNTKQLSD 770
           C FP+  T +      L +   + YK    K       F  + D P  + A    K  SD
Sbjct: 5   CLFPKPHTYDLS----LPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSD 60

Query: 771 LNYKAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLL 830
             YK  +E  K   + P D    +Q +     +SD  Y     ++   ++    D   ++
Sbjct: 61  REYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY-----RNYLHQWTCLPDQNDVI 115

Query: 831 AAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKN-QSDREYRKDYEKS 889
            AK      SD +YK D E  KG  IG L       M   +K A+N  ++R YR   E  
Sbjct: 116 QAKKAYDLQSDNLYKSDLEWLKG--IGWLPEGSVEVM--RVKNAQNLLNERLYRIKPEAL 171

Query: 890 KTIYTAPLDMLQVTQAKKSQAIASDVD 916
           K  +T+ +D  +V QAK +    S+V+
Sbjct: 172 K--FTSIVDTPEVIQAKINAVQISEVE 196



 Score = 37.4 bits (85), Expect = 0.50
 Identities = 52/208 (25%), Positives = 87/208 (41%), Gaps = 51/208 (24%)

Query: 421 KYKDSYLKDILGHYVGSF---EDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQ 477
           KYK+ Y K  LGH++G     +DP     +      SD+ YK  YE+ +G    P     
Sbjct: 24  KYKEGYRKQ-LGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTP----- 77

Query: 478 EYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKC 537
                                        D   ++QA+     +SD++Y+  +   ++ C
Sbjct: 78  ----------------------------LDMMSIVQAKKCQVLVSDIDYR--NYLHQWTC 107

Query: 538 HIPPDTPAFIQHKVNAYNL-SDNLYKQDWEKSKAKKFDIKVDAIPLLAAKA-NTKNTSDV 595
              PD    IQ K  AY+L SDNLYK D E  K       +  +P  + +    KN  ++
Sbjct: 108 L--PDQNDVIQAK-KAYDLQSDNLYKSDLEWLKG------IGWLPEGSVEVMRVKNAQNL 158

Query: 596 MYKKDYEKNKGKMIGVLSINDDPKMLHS 623
           + ++ Y + K + +   SI D P+++ +
Sbjct: 159 LNERLY-RIKPEALKFTSIVDTPEVIQA 185



 Score = 37.4 bits (85), Expect = 0.50
 Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 10/168 (5%)

Query: 4645 YNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLY 4704
            +  + D P  V A+ +    S+ +YK+ Y + K  + T L+ +   + +  + L S   Y
Sbjct: 39   FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 98

Query: 4705 KEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTA 4764
            +    +       LP     +  AK    L S   Y+ + E  K +  LP   +      
Sbjct: 99   RNYLHQWTC----LPDQN-DVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP---EGSVEVM 150

Query: 4765 RCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEID 4812
            R      L  +RLYR   +   +K   + D  E++ AK +  ++SE++
Sbjct: 151  RVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVE 196


>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
          Length = 261

 Score =  123 bits (309), Expect = 5e-27
 Identities = 94/258 (36%), Positives = 117/258 (45%), Gaps = 66/258 (25%)

Query: 6417 VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTD-PITERVKKNMQDFSDINYRG 6475
            V DTPE  R+++     S V+Y E+FEK+KG    VV D P  +R+KK     S+I Y  
Sbjct: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124

Query: 6476 IQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSR 6535
                  E E+ R                 P      +P   + Q  S +       RR  
Sbjct: 125  ------EFEKSR---------------MGPSGGEGMEPERRDSQDGSSY-------RRPL 156

Query: 6536 EQSRSASALSISGGEEKSEHSEAPDHHLST----YSDGGVFAVSTAYKHAKTTELPQQRS 6591
            EQ +                     HH+ T    Y       V+ +Y   K    P    
Sbjct: 157  EQQQP--------------------HHIPTSAPVYQQPQQQPVAQSYGGYKEPAAP---- 192

Query: 6592 SSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGT 6651
                     VS   S P   GK +RA+YDY AAD DEVSF+DGD I+NVQ ID+GWMYGT
Sbjct: 193  ---------VSIQRSAPGGGGKRYRAVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGT 243

Query: 6652 VQRTGRTGMLPANYVEAI 6669
            V+RTG TGMLPANYVEAI
Sbjct: 244  VERTGDTGMLPANYVEAI 261



 Score = 67.0 bits (162), Expect = 6e-10
 Identities = 31/90 (34%), Positives = 55/90 (61%), Gaps = 8/90 (8%)

Query: 5439 IKYRKNYEKS--------KDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTT 5490
            +K  K YEK         K  FT + DTPE+LR  + ++  S + YK E+ K K +G++ 
Sbjct: 41   MKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSV 100

Query: 5491 IHDTPMLLHVRKVKDEVSDLKYKEVYQRNK 5520
            + DTP L  ++K +D++S++KY E +++++
Sbjct: 101  VADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 62.0 bits (149), Expect = 2e-08
 Identities = 39/112 (34%), Positives = 56/112 (50%), Gaps = 4/112 (3%)

Query: 5339 DLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYAT 5398
            D  W K   C+  +T   TL  KN   Y K  Y       K  F  VAD+P N   K  +
Sbjct: 22   DKFWHKA--CFHCETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQS 78

Query: 5399 QLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSK 5449
            +L ++ +Y+ ++E+ K K + +V D P     K   DQIS IKY + +EKS+
Sbjct: 79   ELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 58.9 bits (141), Expect = 2e-07
 Identities = 27/55 (49%), Positives = 38/55 (69%)

Query: 83  TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKY 137
           TP     ++  +L S  +YKE+FEK KG+ ++   DTPEL+RIKK QDQ+S +KY
Sbjct: 68  TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122



 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 6/84 (7%)

Query: 6109 ENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPG-----TA 6163
            +N K +    Y C+    K   T+V DTPE LR+K+  +  S V YKE+         + 
Sbjct: 42   KNYKGYEKKPY-CNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSV 100

Query: 6164 IGKTPEMMRVKQTQDHISSVKYKE 6187
            +  TPE+ R+K+TQD IS++KY E
Sbjct: 101  VADTPELQRIKKTQDQISNIKYHE 124



 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 1/77 (1%)

Query: 6052 SAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSY-YETVLDTPEIQRVREN 6110
            +A   K +FT V DTPE +  +Q   L SQ +YKE+ EK+    +  V DTPE+QR+++ 
Sbjct: 54   NAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKT 113

Query: 6111 QKNFSLLQYQCDLKNSK 6127
            Q   S ++Y  + + S+
Sbjct: 114  QDQISNIKYHEEFEKSR 130



 Score = 58.2 bits (139), Expect = 3e-07
 Identities = 28/63 (44%), Positives = 39/63 (61%)

Query: 6384 TPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFE 6443
            TPE  R K+  E  S V Y + F K      + V DTPE++R+++TQ  IS +KYHE+FE
Sbjct: 68   TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127

Query: 6444 KHK 6446
            K +
Sbjct: 128  KSR 130



 Score = 57.0 bits (136), Expect = 6e-07
 Identities = 33/101 (32%), Positives = 54/101 (53%), Gaps = 10/101 (9%)

Query: 5393 HFKYATQLMNEKKYRADYEQR--------KDKYHLVVDEPRHLLAKTAGDQISQIKYRKN 5444
            H +     +N K Y+  YE++        K  + +V D P +L  K   +  SQ++Y++ 
Sbjct: 31   HCETCKMTLNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEE 89

Query: 5445 YEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAK 5484
            +EK+K K F+ + DTPE  R  K   QIS+I Y  E+ K++
Sbjct: 90   FEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 32/111 (28%), Positives = 61/111 (54%), Gaps = 6/111 (5%)

Query: 288 KWSETPCFEVANARMNADNISTRKYQED---FENMKDQIYFMQTETPEYKMNKKAGVAAS 344
           K+    CF     +M  +  + + Y++      +   Q + M  +TPE    K+     S
Sbjct: 23  KFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQS 82

Query: 345 KVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTK 395
           +V+YKE++EKNKGK  ++V+  ++ P+L+++K   D +S+  Y E +EK++
Sbjct: 83  QVRYKEEFEKNKGKG-FSVV--ADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 53.5 bits (127), Expect = 7e-06
 Identities = 36/97 (37%), Positives = 49/97 (50%), Gaps = 10/97 (10%)

Query: 5218 HAKDVKDMVSEKKYKIQYEKM--------KDKYTPVPDTPILIRAKRAYWNASDLRYKET 5269
            H +  K  ++ K YK  YEK         K  +T V DTP  +R K+     S +RYKE 
Sbjct: 31   HCETCKMTLNMKNYK-GYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEE 89

Query: 5270 FQKTKGK-YHTVKDALDIVYHRKVTDDISKIKYKENY 5305
            F+K KGK +  V D  ++   +K  D IS IKY E +
Sbjct: 90   FEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126



 Score = 51.6 bits (122), Expect = 3e-05
 Identities = 42/152 (27%), Positives = 68/152 (44%), Gaps = 19/152 (12%)

Query: 6056 EKANFTSVVDTPEIIHAQQVKNLSSQKKYKE-------DAEKSMSYYETVLDTPEIQRVR 6108
            EK N           H +  K   + K YK        +A      +  V DTPE  R++
Sbjct: 16   EKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLK 75

Query: 6109 ENQKNFSLLQYQCDLKNSKGK-ITVVQDTPEILRVKENQKNFSSVLYKED-----VSPGT 6162
            +  +  S ++Y+ + + +KGK  +VV DTPE+ R+K+ Q   S++ Y E+     + P  
Sbjct: 76   QQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSG 135

Query: 6163 AIGKTPEMMRVKQTQDHISSVKYKEAIGQGTP 6194
              G  PE    + +QD  S   Y+  + Q  P
Sbjct: 136  GEGMEPER---RDSQDGSS---YRRPLEQQQP 161



 Score = 51.6 bits (122), Expect = 3e-05
 Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 9/156 (5%)

Query: 196 VKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQ-FT 254
           +KN   + KK Y       K  F    D+PE  R+ Q  +  S V YK+   + + + F+
Sbjct: 41  MKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFS 99

Query: 255 PLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQE 314
            +AD P+++  KK  +Q+S  KY E++E    G     P           D+     Y+ 
Sbjct: 100 VVADTPELQRIKKTQDQISNIKYHEEFEKSRMG-----PSGGEGMEPERRDSQDGSSYRR 154

Query: 315 DFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKE 350
             E  + Q + + T  P Y+  ++  VA S   YKE
Sbjct: 155 PLE--QQQPHHIPTSAPVYQQPQQQPVAQSYGGYKE 188



 Score = 50.8 bits (120), Expect = 4e-05
 Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 9/99 (9%)

Query: 5858 TSQLASSYQYKKKYEKS--------KGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKE 5909
            T ++  + +  K YEK         K  +  + D  E L LK+ +ELQS V+YKE++EK 
Sbjct: 34   TCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN 93

Query: 5910 RGKPM-LDFETPTYITAKESQQMQSGKEYRKDYEESIKG 5947
            +GK   +  +TP     K++Q   S  +Y +++E+S  G
Sbjct: 94   KGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMG 132



 Score = 50.4 bits (119), Expect = 6e-05
 Identities = 37/101 (36%), Positives = 54/101 (53%), Gaps = 8/101 (7%)

Query: 6286 TPLAVTPEMERVKHNQENISSVLYKE----NVGKATATPV-TPEMQRVKRNQENISSVLY 6340
            T +A TPE  R+K   E  S V YKE    N GK  +    TPE+QR+K+ Q+ IS++ Y
Sbjct: 63   TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122

Query: 6341 KENLGKATPTPFTPE-MERVKRNQENFSSVLYKENMRKATP 6380
             E   K+   P   E ME  +R+ ++ SS  Y+  + +  P
Sbjct: 123  HEEFEKSRMGPSGGEGMEPERRDSQDGSS--YRRPLEQQQP 161



 Score = 47.4 bits (111), Expect = 5e-04
 Identities = 25/62 (40%), Positives = 39/62 (62%), Gaps = 5/62 (8%)

Query: 6162 TAIGKTPEMMRVKQTQDHISSVKYKEAI----GQG-TPIPDLPEVKRVKETQKHISSVMY 6216
            T +  TPE +R+KQ  +  S V+YKE      G+G + + D PE++R+K+TQ  IS++ Y
Sbjct: 63   TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122

Query: 6217 KE 6218
             E
Sbjct: 123  HE 124



 Score = 47.4 bits (111), Expect = 5e-04
 Identities = 23/66 (34%), Positives = 40/66 (60%), Gaps = 1/66 (1%)

Query: 6027 MANETPDFMRARNATDIASQIKYKQSAEMEKA-NFTSVVDTPEIIHAQQVKNLSSQKKYK 6085
            M  +TP+ +R +  +++ SQ++YK+  E  K   F+ V DTPE+   ++ ++  S  KY 
Sbjct: 64   MVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYH 123

Query: 6086 EDAEKS 6091
            E+ EKS
Sbjct: 124  EEFEKS 129



 Score = 45.8 bits (107), Expect = 0.001
 Identities = 31/89 (34%), Positives = 46/89 (51%), Gaps = 6/89 (6%)

Query: 6193 TPIPDLPEVKRVKETQKHISSVMYKE----NLGTGIPTTV-TPEIERVKRNQENFSSVLY 6247
            T + D PE  R+K+  +  S V YKE    N G G      TPE++R+K+ Q+  S++ Y
Sbjct: 63   TMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY 122

Query: 6248 KENLGKGIPTPITPE-MERVKRNQENFSS 6275
             E   K    P   E ME  +R+ ++ SS
Sbjct: 123  HEEFEKSRMGPSGGEGMEPERRDSQDGSS 151



 Score = 45.4 bits (106), Expect = 0.002
 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 1/111 (0%)

Query: 3676 DTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWD 3735
            +T ++ L   N     K  Y  A    K S  ++ DTP+ L  K  S   SQ  Y + ++
Sbjct: 33   ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91

Query: 3736 ESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDD 3786
            ++K K + + AD   ++  K ++D  S+ KY E +EK +    G + +E +
Sbjct: 92   KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142



 Score = 45.1 bits (105), Expect = 0.002
 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 6/84 (7%)

Query: 5726 YRKDAKENLHY-----TTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLG-RPD 5779
            Y K    N HY     T VAD P+  +  Q ++  S+V Y+ +  K    G S++   P+
Sbjct: 47   YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPE 106

Query: 5780 IEMAKKAAKLSSQVKYRENFDKEK 5803
            ++  KK     S +KY E F+K +
Sbjct: 107  LQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 44.7 bits (104), Expect = 0.003
 Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 2/73 (2%)

Query: 5985 KGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIA 6044
            +  T + DTP+ LR K  +++ ++  YK + E   KG+G + +A +TP+  R +   D  
Sbjct: 60   QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVA-DTPELQRIKKTQDQI 117

Query: 6045 SQIKYKQSAEMEK 6057
            S IKY +  E  +
Sbjct: 118  SNIKYHEEFEKSR 130



 Score = 44.3 bits (103), Expect = 0.004
 Identities = 23/98 (23%), Positives = 54/98 (55%), Gaps = 6/98 (6%)

Query: 5641 KTVSNLVSENKYKDHVKK-----HLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVK 5695
            +T    ++   YK + KK     H  + S+T + +T + + +K+ ++  S   YK++F K
Sbjct: 33   ETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEK 92

Query: 5696 EKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKEN 5733
             KGK  +S++ + PE++   +   + S++ Y ++ +++
Sbjct: 93   NKGK-GFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129



 Score = 44.3 bits (103), Expect = 0.004
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 3/95 (3%)

Query: 4376 RVTKNQEMMSQIKYKKNALENYP--NFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKG 4433
            ++T N +     + K     +YP  +F  V D PE +  K  S  QS V+YKE F K KG
Sbjct: 36   KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95

Query: 4434 K-YTFSPDTPHISHSKDMGKLYSTILYKGAWEGTK 4467
            K ++   DTP +   K      S I Y   +E ++
Sbjct: 96   KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 43.9 bits (102), Expect = 0.005
 Identities = 24/75 (32%), Positives = 37/75 (49%)

Query: 4672 NYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQ 4731
            N H  K  +T V +T +  R +    L S   YKE +++ K   + + + T  L   K  
Sbjct: 54   NAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKT 113

Query: 4732 KHLASHIKYREEYEK 4746
            +   S+IKY EE+EK
Sbjct: 114  QDQISNIKYHEEFEK 128



 Score = 43.9 bits (102), Expect = 0.005
 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 6353 TPEMERVKRNQENFSSVLYKENMRKA-----TPTPVTPEMERAKRNQENISSVLYSDSFR 6407
            TPE  R+K+  E  S V YKE   K      +    TPE++R K+ Q+ IS++ Y + F 
Sbjct: 68   TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127

Query: 6408 KQIQGKAAYVLDTPEMR 6424
            K   G +      PE R
Sbjct: 128  KSRMGPSGGEGMEPERR 144



 Score = 43.1 bits (100), Expect = 0.009
 Identities = 27/117 (23%), Positives = 55/117 (47%), Gaps = 1/117 (0%)

Query: 1724 KFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKL 1783
            K  +  +T +  LN  N    +K+ Y    +  K +  ++ DTP+ L  +      S   
Sbjct: 27   KACFHCETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVR 85

Query: 1784 YKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDD 1840
            YK  +E+ K KG+ +  D   ++  + ++D  S+ KY + +E+++    G   +E +
Sbjct: 86   YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142



 Score = 43.1 bits (100), Expect = 0.009
 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 9/102 (8%)

Query: 5843 VTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGH-YHTIPDNLEQLHLKEATELQSIVK 5901
            V D  E+L +      S+L S  +YK+++EK+KG  +  + D  E   +K+  +  S +K
Sbjct: 65   VADTPENLRLKQ---QSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 5902 YKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEE 5943
            Y E++EK R  P     +       E +  Q G  YR+  E+
Sbjct: 122  YHEEFEKSRMGP-----SGGEGMEPERRDSQDGSSYRRPLEQ 158



 Score = 42.7 bits (99), Expect = 0.012
 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 36/107 (33%)

Query: 5169 KSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAKDVKDMVSE 5228
            K  FT V DTP+ LR K+  +LQSQ                                   
Sbjct: 59   KQSFTMVADTPENLRLKQQSELQSQV---------------------------------- 84

Query: 5229 KKYKIQYEKMKDK-YTPVPDTPILIRAKRAYWNASDLRYKETFQKTK 5274
             +YK ++EK K K ++ V DTP L R K+     S+++Y E F+K++
Sbjct: 85   -RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 42.7 bits (99), Expect = 0.012
 Identities = 23/70 (32%), Positives = 37/70 (52%)

Query: 2245 KTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIAS 2304
            K    ++ DTP+ L+ KQ   L SQ  YK  +E+   KG+ +  D   +Q  K ++D  S
Sbjct: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118

Query: 2305 DYKYKQGYRK 2314
            + KY + + K
Sbjct: 119  NIKYHEEFEK 128



 Score = 42.7 bits (99), Expect = 0.012
 Identities = 28/110 (25%), Positives = 55/110 (50%), Gaps = 6/110 (5%)

Query: 3914 YTSIVDTPEVVLAKSNAENISIPKYREVWDKDK-TSIHIMPDTPEINLARANALNVSNKL 3972
            +T + DTPE +  K  +E  S  +Y+E ++K+K     ++ DTPE+   +     +SN  
Sbjct: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 3973 YREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHYVGT 4022
            Y E +++ + G         ++  +   +  S Y+  L  E+Q+ H++ T
Sbjct: 122  YHEEFEKSRMGPS---GGEGMEPERRDSQDGSSYRRPL--EQQQPHHIPT 166



 Score = 42.4 bits (98), Expect = 0.016
 Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 4/98 (4%)

Query: 4969 HFKHIKDTRYMSSYFKY-KEAY--EHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELY 5025
            H +  K T  M +Y  Y K+ Y   H     +T+       + +++ + + S+  Y+E +
Sbjct: 31   HCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEF 90

Query: 5026 HKLKDK-IHTTPDTPEIRQVKKTQEAVSELIYKSDFFK 5062
             K K K      DTPE++++KKTQ+ +S + Y  +F K
Sbjct: 91   EKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128



 Score = 42.4 bits (98), Expect = 0.016
 Identities = 25/61 (40%), Positives = 34/61 (55%), Gaps = 5/61 (8%)

Query: 6229 TPEIERVKRNQENFSSVLYKE----NLGKGIPTPI-TPEMERVKRNQENFSSVLYKENMG 6283
            TPE  R+K+  E  S V YKE    N GKG      TPE++R+K+ Q+  S++ Y E   
Sbjct: 68   TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127

Query: 6284 K 6284
            K
Sbjct: 128  K 128



 Score = 41.2 bits (95), Expect = 0.035
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 7/88 (7%)

Query: 525 NYKAKHESEKFKCHIPP-------DTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKV 577
           NYK   +      H P        DTP  ++ K  +   S   YK+++EK+K K F +  
Sbjct: 43  NYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA 102

Query: 578 DAIPLLAAKANTKNTSDVMYKKDYEKNK 605
           D   L   K      S++ Y +++EK++
Sbjct: 103 DTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 41.2 bits (95), Expect = 0.035
 Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 7/88 (7%)

Query: 772 NYKAKHEGEKFKCHIP-------ADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKV 824
           NYK   +      H P       AD P+ ++ +  +   S   YK+++EK+K K F +  
Sbjct: 43  NYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA 102

Query: 825 DAIPLLAAKANTKNTSDVMYKKDYEKSK 852
           D   L   K      S++ Y +++EKS+
Sbjct: 103 DTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 41.2 bits (95), Expect = 0.035
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%)

Query: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSK-YNTPHDMFNVV 1147
            KK Y  A      F  + D P+ +     +++QS   YK+++EK K K ++   D   + 
Sbjct: 49   KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108

Query: 1148 AAKKAQDVVSNVNY 1161
              KK QD +SN+ Y
Sbjct: 109  RIKKTQDQISNIKY 122



 Score = 40.8 bits (94), Expect = 0.046
 Identities = 23/72 (31%), Positives = 38/72 (52%)

Query: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328
            K  +TM  D P+ L+ K  +   S V YK ++     KG +V+ D   +   K +++  S
Sbjct: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118

Query: 1329 DYKYKEAYEKSK 1340
            + KY E +EKS+
Sbjct: 119  NIKYHEEFEKSR 130



 Score = 40.8 bits (94), Expect = 0.046
 Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 2/73 (2%)

Query: 818 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQ 877
           + F +  D    L  K  ++  S V YK+++EK+KGK  G   + D P++    KT    
Sbjct: 60  QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117

Query: 878 SDREYRKDYEKSK 890
           S+ +Y +++EKS+
Sbjct: 118 SNIKYHEEFEKSR 130



 Score = 40.8 bits (94), Expect = 0.046
 Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 7/109 (6%)

Query: 3671 FTCITDTPEIVLAKNNALTMSKHLYTEAWDADK-TSIHVMPDTPDILLAKSNSANISQKL 3729
            FT + DTPE +  K  +   S+  Y E ++ +K     V+ DTP++   K     IS   
Sbjct: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 3730 YTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHI 3778
            Y + +++S+M        +         RD      Y+   E+Q+ HHI
Sbjct: 122  YHEEFEKSRM------GPSGGEGMEPERRDSQDGSSYRRPLEQQQPHHI 164



 Score = 40.4 bits (93), Expect = 0.059
 Identities = 28/111 (25%), Positives = 49/111 (44%), Gaps = 1/111 (0%)

Query: 2947 DSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANE 3006
            ++ +  L   N     K+ Y  A    K    ++ DTPE +  +Q     S+  YK   E
Sbjct: 33   ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91

Query: 3007 EAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDD 3057
            + K KG+ + +D   +   K ++D IS+ KY + + K      G   +E +
Sbjct: 92   KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142



 Score = 40.4 bits (93), Expect = 0.059
 Identities = 23/70 (32%), Positives = 35/70 (50%)

Query: 2731 KTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIAS 2790
            K +  ++ DTPE L  KQ     S+  YK   E+ K KG+ +  D   ++  K ++D  S
Sbjct: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118

Query: 2791 EFKYKEGYRK 2800
              KY E + K
Sbjct: 119  NIKYHEEFEK 128



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 3/95 (3%)

Query: 5924 TAKESQQMQSGKEYRKD--YEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEES 5981
            T K +  M++ K Y K          ++ T +  TP  L +K  +++ S+  Y+++ E++
Sbjct: 34   TCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKN 93

Query: 5982 IRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLE 6016
             +GKG + + DTP++ R K     ++  +Y  + E
Sbjct: 94   -KGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 1/68 (1%)

Query: 4858 VWDTPEILHAKHAYDLRDDIKYKAHMLKTR-NDYKLVTDTPVYVQAVKSGKQLSDAVYHY 4916
            V DTPE L  K   +L+  ++YK    K +   + +V DTP   +  K+  Q+S+  YH 
Sbjct: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124

Query: 4917 DYVHSVRG 4924
            ++  S  G
Sbjct: 125  EFEKSRMG 132



 Score = 39.7 bits (91), Expect = 0.10
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 2/73 (2%)

Query: 571 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQ 630
           + F +  D    L  K  ++  S V YK+++EKNKGK   V++  D P++    K     
Sbjct: 60  QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVA--DTPELQRIKKTQDQI 117

Query: 631 SDRLYKENYEKTK 643
           S+  Y E +EK++
Sbjct: 118 SNIKYHEEFEKSR 130



 Score = 39.3 bits (90), Expect = 0.13
 Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 17/114 (14%)

Query: 3428 FTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAK-----LNRIN 3481
            FT + DTPE +  K  +   ++  Y E ++ +K K   V+ DTPE+   K     ++ I 
Sbjct: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 3482 YSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHI 3535
            Y ++  K  +  S  EG +              RD      Y+    +Q  HHI
Sbjct: 122  YHEEFEKSRMGPSGGEGME-----------PERRDSQDGSSYRRPLEQQQPHHI 164



 Score = 39.3 bits (90), Expect = 0.13
 Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 1/64 (1%)

Query: 4370 DSVDHVRVTKNQEMMSQIKYKKNALENY-PNFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428
            D+ +++R+ +  E+ SQ++YK+   +N    F  V D PE+   K      S++KY E F
Sbjct: 67   DTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126

Query: 4429 NKAK 4432
             K++
Sbjct: 127  EKSR 130



 Score = 38.5 bits (88), Expect = 0.23
 Identities = 18/72 (25%), Positives = 38/72 (52%)

Query: 1513 KHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIAS 1572
            K  +T+  + P+ ++ K  +   S   YK +++K   KG+ +  D   +   K +++  S
Sbjct: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118

Query: 1573 DCKYKEAYEKAK 1584
            + KY E +EK++
Sbjct: 119  NIKYHEEFEKSR 130



 Score = 38.5 bits (88), Expect = 0.23
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 1/66 (1%)

Query: 5315 IPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG-CYAYDTPDFTLAEKNKTLYSKYKYKE 5373
            + D PE+   +  ++  S V+YKE+    KG G     DTP+    +K +   S  KY E
Sbjct: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124

Query: 5374 VFERTK 5379
             FE+++
Sbjct: 125  EFEKSR 130



 Score = 38.5 bits (88), Expect = 0.23
 Identities = 19/67 (28%), Positives = 38/67 (56%), Gaps = 1/67 (1%)

Query: 5631 VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYK 5690
            V DTP+ L  K  S L S+ +YK+  +K+  +G ++ + +T +   +K+    +S+  Y 
Sbjct: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKG-FSVVADTPELQRIKKTQDQISNIKYH 123

Query: 5691 KKFVKEK 5697
            ++F K +
Sbjct: 124  EEFEKSR 130



 Score = 38.1 bits (87), Expect = 0.30
 Identities = 24/97 (24%), Positives = 45/97 (46%), Gaps = 1/97 (1%)

Query: 3190 DSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAME 3249
            ++ +  L   N     K+ Y  A    K    ++ DTPE +  +Q     S+  Y++  E
Sbjct: 33   ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91

Query: 3250 EAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRK 3286
            + K +G+ + +D   +   K ++D  S+ KY E + K
Sbjct: 92   KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128



 Score = 38.1 bits (87), Expect = 0.30
 Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 5026 HKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMIS-LPYTPQVIHCRYVGD 5084
            H  K       DTPE  ++K+  E  S++ YK +F K +G   S +  TP++   +   D
Sbjct: 56   HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115

Query: 5085 ITSDIKYKEDLQ 5096
              S+IKY E+ +
Sbjct: 116  QISNIKYHEEFE 127



 Score = 37.7 bits (86), Expect = 0.39
 Identities = 30/128 (23%), Positives = 53/128 (41%), Gaps = 6/128 (4%)

Query: 4237 HAHHCNDVQSELKYKAEHVKQ--KGHYV--GVPTMRDDPKLVWFEHAGQIQNERLYKEDY 4292
            H   C    +   YK    K     HY       + D P+ +  +   ++Q++  YKE++
Sbjct: 31   HCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEF 90

Query: 4293 HKTKAK-INIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSD 4351
             K K K  ++ AD   +   K+ Q  +S+I Y     +    P   + ++  +  D Q  
Sbjct: 91   EKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR-DSQDG 149

Query: 4352 NVYRADLE 4359
            + YR  LE
Sbjct: 150  SSYRRPLE 157



 Score = 37.7 bits (86), Expect = 0.39
 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 6/94 (6%)

Query: 724 QEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFK 783
           + Y+  +K   C  H    +P K  FT V D+P  L+ +  ++  S + YK + E  K K
Sbjct: 42  KNYKGYEKKPYCNAH----YP-KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK 96

Query: 784 -CHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSK 816
              + AD P+  + +     +S+  Y +++EKS+
Sbjct: 97  GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 37.4 bits (85), Expect = 0.50
 Identities = 28/110 (25%), Positives = 53/110 (48%), Gaps = 4/110 (3%)

Query: 4602 DLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSG 4661
            D  W K   C+  +T ++    K+Y    +  Y  A     Q++ +V DTP  +   Q  
Sbjct: 22   DKFWHKA--CFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFTMVADTPENLRLKQQS 78

Query: 4662 INASEVKYKENYHQIKDK-YTTVLETVDYDRTRNLKNLYSSNLYKEAWDR 4710
               S+V+YKE + + K K ++ V +T +  R +  ++  S+  Y E +++
Sbjct: 79   ELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128



 Score = 37.4 bits (85), Expect = 0.50
 Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 1/111 (0%)

Query: 1974 DSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLE 2033
            ++  M L   N K   +  Y  A    K    ++ D P+ +  K  +   S   YK   E
Sbjct: 33   ETCKMTLNMKNYKGYEKKPYCNA-HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFE 91

Query: 2034 ESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDD 2084
            ++K KG+ +  D   ++  K ++D  S+ KY   +EK +    G   +E +
Sbjct: 92   KNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPE 142



 Score = 37.4 bits (85), Expect = 0.50
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 1061 KKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKI 1120
            K+ + +  D       K   +  S V+YK+++EK KGK  GF  + D P+L         
Sbjct: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQ 116

Query: 1121 QSDREYKKDYEKTK 1134
             S+ +Y +++EK++
Sbjct: 117  ISNIKYHEEFEKSR 130



 Score = 37.0 bits (84), Expect = 0.66
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 1/85 (1%)

Query: 1821 KKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSK-TSFHTPVDMLSVV 1879
            KK Y  A      F  + D P+ +   Q +++QS   YK+ +EK+K   F    D   + 
Sbjct: 49   KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108

Query: 1880 AAKKSQEVATNANYRNVIHTYNMLP 1904
              KK+Q+  +N  Y        M P
Sbjct: 109  RIKKTQDQISNIKYHEEFEKSRMGP 133



 Score = 37.0 bits (84), Expect = 0.66
 Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 1/61 (1%)

Query: 5778 PDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLK 5837
            P+    K+ ++L SQV+Y+E F+K KGK         +L ++ K  + + S +KY  + +
Sbjct: 69   PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQI-SNIKYHEEFE 127

Query: 5838 K 5838
            K
Sbjct: 128  K 128



 Score = 36.6 bits (83), Expect = 0.86
 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 7/117 (5%)

Query: 3765 KYKEAYEKQK--GHHIGAQS---IEDDPKIMCAIHAGKIQSEREYKKEFQKWKTK-FSSP 3818
            K  + YEK+     H   QS   + D P+ +      ++QS+  YK+EF+K K K FS  
Sbjct: 42   KNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVV 101

Query: 3819 VDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLE 3875
             D   +   KK Q  +++I Y     +    P   + ++ ++  D Q  + Y+  LE
Sbjct: 102  ADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157



 Score = 36.2 bits (82), Expect = 1.1
 Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query: 5918 ETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKD 5977
            +TP  +  K+  ++QS   Y++++E++ KG+  + +  TP L  +K      S  +Y ++
Sbjct: 67   DTPENLRLKQQSELQSQVRYKEEFEKN-KGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125

Query: 5978 LEESIRG 5984
             E+S  G
Sbjct: 126  FEKSRMG 132



 Score = 35.8 bits (81), Expect = 1.5
 Identities = 41/171 (23%), Positives = 65/171 (38%), Gaps = 13/171 (7%)

Query: 397 KSINYCETPKFKLDTVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDK 456
           K+  +CET K  L+         K Y +++        V   + P +    + +   S  
Sbjct: 27  KACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVA--DTPENLRLKQQSELQSQV 84

Query: 457 NYKAEYEEDRGKGFFPQTITQEYEAIKKL-DQCKDHTYKVHPDKTKFTQVTD---SPVLL 512
            YK E+E+++GKGF     T E + IKK  DQ  +  Y    +K++          P   
Sbjct: 85  RYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR 144

Query: 513 QAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQHKVNAYNLSDNLYKQ 563
            +Q  S     L  +  H       HIP   P + Q +      S   YK+
Sbjct: 145 DSQDGSSYRRPLEQQQPH-------HIPTSAPVYQQPQQQPVAQSYGGYKE 188



 Score = 35.8 bits (81), Expect = 1.5
 Identities = 35/152 (23%), Positives = 60/152 (39%), Gaps = 24/152 (15%)

Query: 3164 CKRAAEILSDNIYRQPP------DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDK 3217
            CK    + +   Y + P       K  FT V D+ E +  K  +   ++  Y E ++K+K
Sbjct: 35   CKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNK 94

Query: 3218 TQ-VHIMPDTPEIMLARQ-----NKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKAS 3271
             +   ++ DTPE+   ++     + I Y E   +  M  +  EG +              
Sbjct: 95   GKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGME-----------PER 143

Query: 3272 RDIASDYKYKEAYRKQLGHHIGARA-VHDDPK 3302
            RD      Y+    +Q  HHI   A V+  P+
Sbjct: 144  RDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQ 175



 Score = 35.8 bits (81), Expect = 1.5
 Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 1/64 (1%)

Query: 180 KDKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSL-FYPYNDSPELRRVAQAQKALS 238
           K  + +  D PE ++  + + + S+  Y E++E +K   F    D+PEL+R+ + Q  +S
Sbjct: 59  KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118

Query: 239 DVAY 242
           ++ Y
Sbjct: 119 NIKY 122



 Score = 35.4 bits (80), Expect = 1.9
 Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 8/121 (6%)

Query: 5513 KEVYQRNKSNCTIE---PDAVHIKAAKDAYKVNTNLDYKKQYEAN----KAHWKWTPDRP 5565
            K VY   K NC  +       H +  K    +     Y+K+   N    K  +    D P
Sbjct: 10   KIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTP 69

Query: 5566 DFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIE-SDLKYKEKHVKE 5624
            + L+  + S  QS   YK + E  KG   SV  D   +  ++ T  + S++KY E+  K 
Sbjct: 70   ENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129

Query: 5625 R 5625
            R
Sbjct: 130  R 130



 Score = 35.0 bits (79), Expect = 2.5
 Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 17/97 (17%)

Query: 2029 KLSLEESKKKGYDLRP---------------DAIPIKAAKASRDIASDYKYKYNYEKGKG 2073
            K++L     KGY+ +P               D       K   ++ S  +YK  +EK KG
Sbjct: 36   KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95

Query: 2074 KMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTK 2110
            K  GF  + D P+L    +     S+ +Y + +E ++
Sbjct: 96   K--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 34.7 bits (78), Expect = 3.3
 Identities = 25/97 (25%), Positives = 48/97 (49%), Gaps = 2/97 (2%)

Query: 2322 FRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQELVSDVD 2380
            F  + D P+ +     +++QS+  YK++FEK K K FS   D   +   KK Q+ +S++ 
Sbjct: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 2381 YKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLE 2417
            Y     +    P   + ++ ++  + Q  + Y+  LE
Sbjct: 122  YHEEFEKSRMGPSGGEGMEPER-RDSQDGSSYRRPLE 157



 Score = 34.7 bits (78), Expect = 3.3
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 2/94 (2%)

Query: 3540 IKDDPKMMWSIHVAKIQSDREYKKEFEKWKTK-FSSPVDMLGVVLAKKCQILVSDIDYKH 3598
            + D P+ +     +++QS   YK+EFEK K K FS   D   +   KK Q  +S+I Y  
Sbjct: 65   VADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHE 124

Query: 3599 PLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLE 3632
               +    P   + ++  +  D Q  + Y+  LE
Sbjct: 125  EFEKSRMGPSGGEGMEPERR-DSQDGSSYRRPLE 157



 Score = 34.7 bits (78), Expect = 3.3
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 367 SENPQLRQLKAAGDALSDKLYKENYEKTKAKSIN-YCETPKFKLDTVLQNFSSDKKYKDS 425
           ++ P+  +LK   +  S   YKE +EK K K  +   +TP+ +     Q+  S+ KY + 
Sbjct: 66  ADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125

Query: 426 YLKDILGHYVGSFEDP 441
           + K  +G   G   +P
Sbjct: 126 FEKSRMGPSGGEGMEP 141



 Score = 34.7 bits (78), Expect = 3.3
 Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%)

Query: 5073 TPQVIHCRYVGDITSDIKYKEDLQVLKGFG-CFLYDTPDMVRSRHLRKLWSNYLYTDKAR 5131
            TP+ +  +   ++ S ++YKE+ +  KG G   + DTP++ R +  +   SN  Y ++  
Sbjct: 68   TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127

Query: 5132 KMR 5134
            K R
Sbjct: 128  KSR 130



 Score = 34.7 bits (78), Expect = 3.3
 Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%)

Query: 1321 KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTK 1378
            K    + S  +YKE +EK+KGK  GF  + D P+L          S+ +Y + +E ++
Sbjct: 75   KQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 34.3 bits (77), Expect = 4.3
 Identities = 21/84 (25%), Positives = 37/84 (44%)

Query: 2488 KTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIAS 2547
            K    ++ DTP+ +  K      S   Y+  +E+ K KG+ +  D   ++  K +++  S
Sbjct: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118

Query: 2548 EYKYKEGFRKQLGHHIGARNIEDD 2571
              KY E F K      G   +E +
Sbjct: 119  NIKYHEEFEKSRMGPSGGEGMEPE 142



 Score = 33.9 bits (76), Expect = 5.6
 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 1577 KEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK-YHTPLDMVSVT 1635
            K+ Y  A   +  F  + D P+ +     +++QS   YK+ +E +K K +    D   + 
Sbjct: 49   KKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQ 108

Query: 1636 AAKKSQEVATNANYRQSYHHYTLLP 1660
              KK+Q+  +N  Y + +    + P
Sbjct: 109  RIKKTQDQISNIKYHEEFEKSRMGP 133



 Score = 33.9 bits (76), Expect = 5.6
 Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 1/71 (1%)

Query: 111 QPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAK-TICHVDEKAKDIEHAKKVSQQVSK 169
           Q +    DTPE  R+K+  +  S+V+Y+ + +  K     V     +++  KK   Q+S 
Sbjct: 60  QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISN 119

Query: 170 VLYKQNWEDTK 180
           + Y + +E ++
Sbjct: 120 IKYHEEFEKSR 130



 Score = 33.5 bits (75), Expect = 7.3
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 10/88 (11%)

Query: 1223 LNEKKYR---------QHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHK-Y 1272
            LN K Y+          H     FT + D+P  ++ KQ ++  S + YK + E  K K +
Sbjct: 39   LNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGF 98

Query: 1273 TMSPDLPQFLQAKCNAYNISDVCYKRDW 1300
            ++  D P+  + K     IS++ Y  ++
Sbjct: 99   SVVADTPELQRIKKTQDQISNIKYHEEF 126



 Score = 33.5 bits (75), Expect = 7.3
 Identities = 17/68 (25%), Positives = 39/68 (57%), Gaps = 1/68 (1%)

Query: 3598 HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGW-VPIGSVEVEKVKRAGEI 3656
            +P   +T + D  + ++ ++  +LQS   YK + E  +G G+ V   + E++++K+  + 
Sbjct: 57   YPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQ 116

Query: 3657 LSDRKYRQ 3664
            +S+ KY +
Sbjct: 117  ISNIKYHE 124



 Score = 33.1 bits (74), Expect = 9.5
 Identities = 49/232 (21%), Positives = 84/232 (36%), Gaps = 32/232 (13%)

Query: 1719 HPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDK-TTIHVMPDTPDILLSRVNQI 1777
            H  K  FT   DT E    K       +  Y E++ K+K     V+ DTP++   +  Q 
Sbjct: 56   HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115

Query: 1778 TMSDKLYKAGWEEEK---KKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGF 1834
             +S+  Y   +E+ +     G  + P+          RD      Y++  EQ +  HI  
Sbjct: 116  QISNIKYHEEFEKSRMGPSGGEGMEPE---------RRDSQDGSSYRRPLEQQQPHHI-- 164

Query: 1835 RSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYR 1894
                  P      Q  + Q   +   GY+          +  + V+ ++S        YR
Sbjct: 165  ------PTSAPVYQQPQQQPVAQSYGGYK----------EPAAPVSIQRSAPGGGGKRYR 208

Query: 1895 NVIHTYNMLPDAMSFELAKNMMQIQS-DNQYKADYADFMKGIGWLPLGSLEA 1945
             V        D +SF+    ++ +Q  D+ +     +     G LP   +EA
Sbjct: 209  AVYDYSAADEDEVSFQDGDTIVNVQQIDDGWMYGTVERTGDTGMLPANYVEA 260



 Score = 33.1 bits (74), Expect = 9.5
 Identities = 15/81 (18%), Positives = 41/81 (50%)

Query: 1028 YNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQ 1087
            + +  D P+ ++ K  +   S+  YK + +    KG+ +  D   ++  K  +   S+++
Sbjct: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 1088 YKKDYEKAKGKMVGFQSLQDD 1108
            Y +++EK++    G + ++ +
Sbjct: 122  YHEEFEKSRMGPSGGEGMEPE 142



 Score = 33.1 bits (74), Expect = 9.5
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 2/58 (3%)

Query: 1565 KSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASK 1622
            K    + S  +YKE +EK KGK  GF  + D P+L          S+ +Y + +E S+
Sbjct: 75   KQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130


>gi|47087157 nebulette non-muscle isoform [Homo sapiens]
          Length = 270

 Score =  102 bits (254), Expect = 1e-20
 Identities = 49/73 (67%), Positives = 59/73 (80%), Gaps = 1/73 (1%)

Query: 6598 QTTVSSIPSHPSTAG-KIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTG 6656
            QT+VSS+ S   +   + +RAMYDY A D DEVSF+DGD I+NVQ ID+GWMYGTVQRTG
Sbjct: 197  QTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGTVQRTG 256

Query: 6657 RTGMLPANYVEAI 6669
            RTGMLPANY+E +
Sbjct: 257  RTGMLPANYIEFV 269



 Score = 99.0 bits (245), Expect = 1e-19
 Identities = 52/104 (50%), Positives = 67/104 (64%), Gaps = 1/104 (0%)

Query: 6384 TPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHISTVKYHEDFE 6443
            TPE  R K+  E  S V Y   F +      + V DTPE++R++ TQ  IS VKYHEDFE
Sbjct: 68   TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127

Query: 6444 KHKG-CFTPVVTDPITERVKKNMQDFSDINYRGIQRKVVEMEQK 6486
            K KG  FTPVV DP+TERV+KN Q  SD  Y+G+   +VEM+++
Sbjct: 128  KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRR 171



 Score = 78.2 bits (191), Expect = 3e-13
 Identities = 42/115 (36%), Positives = 65/115 (56%), Gaps = 1/115 (0%)

Query: 5403 EKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEH 5461
            EKK   +    K  +  V D P +L  K   +  SQ+KY++++E+SK + F+ + DTPE 
Sbjct: 48   EKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPEL 107

Query: 5462 LRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVY 5516
             R  +  +QIS++ Y  ++ K K RG+T + D P+   VRK    VSD  YK V+
Sbjct: 108  QRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162



 Score = 73.9 bits (180), Expect = 5e-12
 Identities = 42/106 (39%), Positives = 61/106 (57%), Gaps = 2/106 (1%)

Query: 6052 SAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSY-YETVLDTPEIQRVREN 6110
            +A   K +FT+V DTPE +  +Q   L SQ KYK D E+S    +  V DTPE+QR++  
Sbjct: 54   NAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRT 113

Query: 6111 QKNFSLLQYQCDLKNSKGK-ITVVQDTPEILRVKENQKNFSSVLYK 6155
            Q+  S ++Y  D + +KG+  T V D P   RV++N +  S   YK
Sbjct: 114  QEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 73.6 bits (179), Expect = 6e-12
 Identities = 47/141 (33%), Positives = 70/141 (49%), Gaps = 5/141 (3%)

Query: 5339 DLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINRHFKYAT 5398
            D  W KG  C+  +     L   N   Y K  Y       K  F  VAD+P N   K  +
Sbjct: 22   DKYWHKG--CFHCEVCKMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQS 78

Query: 5399 QLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK-FTSIV 5456
            +L ++ KY+ D+E+ K + + +V D P     K   +QIS +KY +++EK+K + FT +V
Sbjct: 79   ELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVV 138

Query: 5457 DTPEHLRTTKVNKQISDILYK 5477
            D P   R  K  + +SD  YK
Sbjct: 139  DDPVTERVRKNTQVVSDAAYK 159



 Score = 67.0 bits (162), Expect = 6e-10
 Identities = 44/118 (37%), Positives = 61/118 (51%), Gaps = 11/118 (9%)

Query: 6110 NQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIG---- 6165
            N K +    Y C+    K   T V DTPE LR+K+  +  S V YK D       G    
Sbjct: 43   NYKGYEKKPY-CNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIV 101

Query: 6166 -KTPEMMRVKQTQDHISSVKYKEAI----GQG-TPIPDLPEVKRVKETQKHISSVMYK 6217
              TPE+ R+K+TQ+ IS+VKY E      G+G TP+ D P  +RV++  + +S   YK
Sbjct: 102  TDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 63.2 bits (152), Expect = 9e-09
 Identities = 28/86 (32%), Positives = 54/86 (62%), Gaps = 8/86 (9%)

Query: 5443 KNYEKS--------KDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDT 5494
            K YEK         K  FT++ DTPE+LR  + ++  S + YK ++ ++K RG++ + DT
Sbjct: 45   KGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDT 104

Query: 5495 PMLLHVRKVKDEVSDLKYKEVYQRNK 5520
            P L  +++ ++++S++KY E +++ K
Sbjct: 105  PELQRLKRTQEQISNVKYHEDFEKTK 130



 Score = 60.5 bits (145), Expect = 6e-08
 Identities = 39/125 (31%), Positives = 65/125 (52%), Gaps = 10/125 (8%)

Query: 5860 QLASSYQYKKKYEKS--------KGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERG 5911
            ++A +    K YEK         K  + T+ D  E L LK+ +ELQS VKYK  +E+ +G
Sbjct: 36   KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95

Query: 5912 KPM-LDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIAS 5970
            +   +  +TP     K +Q+  S  +Y +D+E++ KGR  T +   P    V+  T++ S
Sbjct: 96   RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT-KGRGFTPVVDDPVTERVRKNTQVVS 154

Query: 5971 EKEYR 5975
            +  Y+
Sbjct: 155  DAAYK 159



 Score = 60.1 bits (144), Expect = 7e-08
 Identities = 38/120 (31%), Positives = 64/120 (53%), Gaps = 10/120 (8%)

Query: 6077 NLSSQKKYKEDAEKSMSY----YETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGK-IT 6131
            N+++ K Y++    +  Y    + TV DTPE  R+++  +  S ++Y+ D + SKG+  +
Sbjct: 40   NMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFS 99

Query: 6132 VVQDTPEILRVKENQKNFSSVLYKEDVSPGTAIGKTPEM-----MRVKQTQDHISSVKYK 6186
            +V DTPE+ R+K  Q+  S+V Y ED       G TP +      RV++    +S   YK
Sbjct: 100  IVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 5/94 (5%)

Query: 83  TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGD 142
           TP     ++  +L S  KYK  FE++KG+ ++  TDTPEL+R+K+ Q+Q+S VKY  D +
Sbjct: 68  TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127

Query: 143 VAK---TICHVDEKAKDIEHAKKVSQQVSKVLYK 173
             K       VD+     E  +K +Q VS   YK
Sbjct: 128 KTKGRGFTPVVDDPV--TERVRKNTQVVSDAAYK 159



 Score = 58.9 bits (141), Expect = 2e-07
 Identities = 31/95 (32%), Positives = 56/95 (58%), Gaps = 2/95 (2%)

Query: 5918 ETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKD 5977
            +TP  +  K+  ++QS  +Y++D+EES KGR  + +  TP L  +K   +  S  +Y +D
Sbjct: 67   DTPENLRLKQQSELQSQVKYKRDFEES-KGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125

Query: 5978 LEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYK 6012
             E++ +G+G T + D P   R +  TQ++++  YK
Sbjct: 126  FEKT-KGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 58.2 bits (139), Expect = 3e-07
 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 3/102 (2%)

Query: 5985 KGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIA 6044
            +  T + DTP+ LR K  +++ ++ +YKRD E E KGRG  ++  +TP+  R +   +  
Sbjct: 60   QSFTTVADTPENLRLKQQSELQSQVKYKRDFE-ESKGRGF-SIVTDTPELQRLKRTQEQI 117

Query: 6045 SQIKYKQSAEMEKA-NFTSVVDTPEIIHAQQVKNLSSQKKYK 6085
            S +KY +  E  K   FT VVD P     ++   + S   YK
Sbjct: 118  SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 57.8 bits (138), Expect = 4e-07
 Identities = 42/160 (26%), Positives = 73/160 (45%), Gaps = 7/160 (4%)

Query: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328
            K  +T   D P+ L+ K  +   S V YKRD+ +   +G +++ D   +   K ++   S
Sbjct: 59   KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 1329 DYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV 1388
            + KY E +EK+KG+  GF  + DDP         ++ SD  YK  + +       PG +V
Sbjct: 119  NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV 176

Query: 1389 S-ITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNV 1427
            + +      Q  +    Y     H T +    S++H+ N+
Sbjct: 177  APVLPGAYQQSHSQGYGYM----HQTSVSSMRSMQHSPNL 212



 Score = 57.4 bits (137), Expect = 5e-07
 Identities = 38/141 (26%), Positives = 72/141 (51%), Gaps = 12/141 (8%)

Query: 5650 NKYKDHVKK-----HLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSI 5704
            N YK + KK     H  + S+TT+ +T + + +K+ ++  S   YK+ F + KG+  +SI
Sbjct: 42   NNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR-GFSI 100

Query: 5705 MLEPPEVKHAMEVAKKQSDVAYRKDAK--ENLHYTTVADRPDIKKATQAAKQASEVEYRA 5762
            + + PE++      ++ S+V Y +D +  +   +T V D P  ++  +  +  S+  Y+ 
Sbjct: 101  VTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKG 160

Query: 5763 KHRKEGSHGLSMLGRPDIEMA 5783
             H     H + M  RP I +A
Sbjct: 161  VH----PHIVEMDRRPGIIVA 177



 Score = 57.4 bits (137), Expect = 5e-07
 Identities = 32/103 (31%), Positives = 58/103 (56%), Gaps = 3/103 (2%)

Query: 5948 RNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILN 6007
            ++ T +  TP  L +K  +++ S+ +Y++D EES +G+G + + DTP++ R K   + ++
Sbjct: 60   QSFTTVADTPENLRLKQQSELQSQVKYKRDFEES-KGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 6008 EKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYK 6050
              +Y  D E + KGRG   + ++ P   R R  T + S   YK
Sbjct: 119  NVKYHEDFE-KTKGRGFTPVVDD-PVTERVRKNTQVVSDAAYK 159



 Score = 56.2 bits (134), Expect = 1e-06
 Identities = 39/97 (40%), Positives = 52/97 (53%), Gaps = 10/97 (10%)

Query: 6286 TPLAVTPEMERVKHNQENISSVLYK----ENVGKATATPV-TPEMQRVKRNQENISSVLY 6340
            T +A TPE  R+K   E  S V YK    E+ G+  +    TPE+QR+KR QE IS+V Y
Sbjct: 63   TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122

Query: 6341 KENLGKATPTPFTPEM-----ERVKRNQENFSSVLYK 6372
             E+  K     FTP +     ERV++N +  S   YK
Sbjct: 123  HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 54.7 bits (130), Expect = 3e-06
 Identities = 35/136 (25%), Positives = 65/136 (47%), Gaps = 3/136 (2%)

Query: 1724 KFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKL 1783
            K  +  +  + ALN +N    +K+ Y    +  K +   + DTP+ L  +      S   
Sbjct: 27   KGCFHCEVCKMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVK 85

Query: 1784 YKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKL 1843
            YK  +EE K +G+ +  D   ++  + +++  S+ KY + +E+ KG+  GF  + DDP  
Sbjct: 86   YKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVT 143

Query: 1844 VHFMQVAKMQSDREYK 1859
                +  ++ SD  YK
Sbjct: 144  ERVRKNTQVVSDAAYK 159



 Score = 54.7 bits (130), Expect = 3e-06
 Identities = 40/97 (41%), Positives = 54/97 (55%), Gaps = 12/97 (12%)

Query: 6226 TTV--TPEIERVKRNQENFSSVLYK----ENLGKGIPTPI-TPEMERVKRNQENFSSVLY 6278
            TTV  TPE  R+K+  E  S V YK    E+ G+G      TPE++R+KR QE  S+V Y
Sbjct: 63   TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122

Query: 6279 KENM----GKG-TPLAVTPEMERVKHNQENISSVLYK 6310
             E+     G+G TP+   P  ERV+ N + +S   YK
Sbjct: 123  HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 9/119 (7%)

Query: 525 NYKAKHESEKFKCHIPP-------DTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKV 577
           NYK   +      H P        DTP  ++ K  +   S   YK+D+E+SK + F I  
Sbjct: 43  NYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVT 102

Query: 578 DAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYK 636
           D   L   K   +  S+V Y +D+EK KG+  G   + DDP      K  +  SD  YK
Sbjct: 103 DTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 38/98 (38%), Positives = 53/98 (54%), Gaps = 12/98 (12%)

Query: 6193 TPIPDLPEVKRVKETQKHISSVMYK----ENLGTGIP-TTVTPEIERVKRNQENFSSVLY 6247
            T + D PE  R+K+  +  S V YK    E+ G G    T TPE++R+KR QE  S+V Y
Sbjct: 63   TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122

Query: 6248 KENL----GKGIPTPIT--PEMERVKRNQENFSSVLYK 6279
             E+     G+G  TP+   P  ERV++N +  S   YK
Sbjct: 123  HEDFEKTKGRGF-TPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 53.5 bits (127), Expect = 7e-06
 Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 9/119 (7%)

Query: 772 NYKAKHEGEKFKCHIP-------ADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKV 824
           NYK   +      H P       AD P+ ++ +  +   S   YK+D+E+SK + F I  
Sbjct: 43  NYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVT 102

Query: 825 DAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYR 883
           D   L   K   +  S+V Y +D+EK+KG+  G   + DDP      K  +  SD  Y+
Sbjct: 103 DTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 53.1 bits (126), Expect = 9e-06
 Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 2/95 (2%)

Query: 1033 DLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDY 1092
            D P+ ++ K  +   S+  YK D ++   +G+ + TD   ++  K  ++  S+V+Y +D+
Sbjct: 67   DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126

Query: 1093 EKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYK 1127
            EK KG+  GF  + DDP         ++ SD  YK
Sbjct: 127  EKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 52.8 bits (125), Expect = 1e-05
 Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 2/101 (1%)

Query: 5169 KSIFTSVPDTPDLLRAKRGQKLQSQYLYV-ELATKERPHHHAGNQTTALKHAKDVKDMVS 5227
            K  FT+V DTP+ LR K+  +LQSQ  Y  +    +         T  L+  K  ++ +S
Sbjct: 59   KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 5228 EKKYKIQYEKMKDK-YTPVPDTPILIRAKRAYWNASDLRYK 5267
              KY   +EK K + +TPV D P+  R ++     SD  YK
Sbjct: 119  NVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 52.4 bits (124), Expect = 2e-05
 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 2/111 (1%)

Query: 4672 NYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQ 4731
            N H  K  +TTV +T +  R +    L S   YK  ++  K   + + + T  L   K  
Sbjct: 54   NAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRT 113

Query: 4732 KHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVY 4782
            +   S++KY E++EK K     P  V DDP T R  +  ++  D  Y+ V+
Sbjct: 114  QEQISNVKYHEDFEKTKGRGFTP--VVDDPVTERVRKNTQVVSDAAYKGVH 162



 Score = 52.4 bits (124), Expect = 2e-05
 Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 10/96 (10%)

Query: 6317 TATPVTPEMQRVKRNQENISSVLYKENLGKATPTPF-----TPEMERVKRNQENFSSVLY 6371
            T    TPE  R+K+  E  S V YK +  ++    F     TPE++R+KR QE  S+V Y
Sbjct: 63   TTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKY 122

Query: 6372 KENMRKA-----TPTPVTPEMERAKRNQENISSVLY 6402
             E+  K      TP    P  ER ++N + +S   Y
Sbjct: 123  HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158



 Score = 52.4 bits (124), Expect = 2e-05
 Identities = 31/99 (31%), Positives = 51/99 (51%), Gaps = 5/99 (5%)

Query: 290 SETPCFEVANARMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYK 349
           ++TP  E    +  ++  S  KY+ DFE  K + + + T+TPE +  K+     S VKY 
Sbjct: 66  ADTP--ENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123

Query: 350 EDYEKNKGKADYNVLPASENPQLRQLKAAGDALSDKLYK 388
           ED+EK KG+      P  ++P   +++     +SD  YK
Sbjct: 124 EDFEKTKGR---GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 52.0 bits (123), Expect = 2e-05
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 2/103 (1%)

Query: 2245 KTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIAS 2304
            K     + DTP+ L+ KQ   L SQ  YK  +EE+  +G+ +  D   +Q  K +++  S
Sbjct: 59   KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 2305 DYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYK 2347
            + KY + + K  G   GF  + DDP         ++ S+  YK
Sbjct: 119  NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 52.0 bits (123), Expect = 2e-05
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 2/96 (2%)

Query: 5314 SIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG-CYAYDTPDFTLAEKNKTLYSKYKYK 5372
            ++ D PE+   +  ++  S VKYK D    KG G     DTP+    ++ +   S  KY 
Sbjct: 64   TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123

Query: 5373 EVFERTKS-DFKYVADSPINRHFKYATQLMNEKKYR 5407
            E FE+TK   F  V D P+    +  TQ++++  Y+
Sbjct: 124  EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 51.6 bits (122), Expect = 3e-05
 Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 3/126 (2%)

Query: 1978 MVLAQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKK 2037
            M L  NN K   +  Y  A    K     + D P+ +  K  +   S   YK   EESK 
Sbjct: 37   MALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95

Query: 2038 KGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQ 2097
            +G+ +  D   ++  K +++  S+ KY  ++EK KG+  GF  + DDP      +  ++ 
Sbjct: 96   RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVV 153

Query: 2098 SDREYK 2103
            SD  YK
Sbjct: 154  SDAAYK 159



 Score = 50.8 bits (120), Expect = 4e-05
 Identities = 37/158 (23%), Positives = 69/158 (43%), Gaps = 5/158 (3%)

Query: 1513 KHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIAS 1572
            K  +T   + P+ ++ K  +   S   YK D++++  +G+ +  D   +   K ++   S
Sbjct: 59   KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 1573 DCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMV 1632
            + KY E +EK KG+  GF  + DDP         ++ SD  YK  +         P  +V
Sbjct: 119  NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIV 176

Query: 1633 SVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRN 1670
            +       Q+   + +    Y H T +    +++HS N
Sbjct: 177  APVLPGAYQQ---SHSQGYGYMHQTSVSSMRSMQHSPN 211



 Score = 50.4 bits (119), Expect = 6e-05
 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 6/121 (4%)

Query: 479 YEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFK-C 537
           Y+  +K   C  H    +P K  FT V D+P  L+ +  S+  S + YK   E  K +  
Sbjct: 44  YKGYEKKPYCNAH----YP-KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGF 98

Query: 538 HIPPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMY 597
            I  DTP   + K     +S+  Y +D+EK+K + F   VD       + NT+  SD  Y
Sbjct: 99  SIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158

Query: 598 K 598
           K
Sbjct: 159 K 159



 Score = 50.4 bits (119), Expect = 6e-05
 Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 2/112 (1%)

Query: 5228 EKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGK-YHTVKDALDI 5286
            EKK        K  +T V DTP  +R K+     S ++YK  F+++KG+ +  V D  ++
Sbjct: 48   EKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPEL 107

Query: 5287 VYHRKVTDDISKIKYKENYMSQLGI-WRSIPDRPEHFHHRAVTDTVSDVKYK 5337
               ++  + IS +KY E++    G  +  + D P     R  T  VSD  YK
Sbjct: 108  QRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 50.1 bits (118), Expect = 8e-05
 Identities = 37/105 (35%), Positives = 52/105 (49%), Gaps = 6/105 (5%)

Query: 4374 HVRVTKNQEMMSQIK-YKKNALEN--YP--NFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428
            H  V K    M+  K Y+K    N  YP  +F +V D PE +  K  S  QS VKYK  F
Sbjct: 31   HCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDF 90

Query: 4429 NKAKGK-YTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYT 4472
             ++KG+ ++   DTP +   K   +  S + Y   +E TK  G+T
Sbjct: 91   EESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135



 Score = 50.1 bits (118), Expect = 8e-05
 Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 3/127 (2%)

Query: 3679 EIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESK 3738
            ++ L  NN     K  Y  A    K S   + DTP+ L  K  S   SQ  Y + ++ESK
Sbjct: 36   KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94

Query: 3739 MKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKI 3798
             + + +  D   ++  K +++  S+ KY E +EK KG   G   + DDP         ++
Sbjct: 95   GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152

Query: 3799 QSEREYK 3805
             S+  YK
Sbjct: 153  VSDAAYK 159



 Score = 49.3 bits (116), Expect = 1e-04
 Identities = 25/76 (32%), Positives = 48/76 (63%), Gaps = 3/76 (3%)

Query: 322 QIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDA 381
           Q +    +TPE    K+     S+VKYK D+E++KG+  ++++  ++ P+L++LK   + 
Sbjct: 60  QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRG-FSIV--TDTPELQRLKRTQEQ 116

Query: 382 LSDKLYKENYEKTKAK 397
           +S+  Y E++EKTK +
Sbjct: 117 ISNVKYHEDFEKTKGR 132



 Score = 49.3 bits (116), Expect = 1e-04
 Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 2/94 (2%)

Query: 4370 DSVDHVRVTKNQEMMSQIKYKKNALENY-PNFRSVVDPPEIVLAKINSVNQSDVKYKETF 4428
            D+ +++R+ +  E+ SQ+KYK++  E+    F  V D PE+   K      S+VKY E F
Sbjct: 67   DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126

Query: 4429 NKAKGK-YTFSPDTPHISHSKDMGKLYSTILYKG 4461
             K KG+ +T   D P     +   ++ S   YKG
Sbjct: 127  EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKG 160



 Score = 48.9 bits (115), Expect = 2e-04
 Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 3/104 (2%)

Query: 818 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQ 877
           + F    D    L  K  ++  S V YK+D+E+SKG+  G   + D P++    +T +  
Sbjct: 60  QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117

Query: 878 SDREYRKDYEKSK-TIYTAPLDMLQVTQAKKSQAIASDVDYKHI 920
           S+ +Y +D+EK+K   +T  +D     + +K+  + SD  YK +
Sbjct: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGV 161



 Score = 48.5 bits (114), Expect = 2e-04
 Identities = 29/81 (35%), Positives = 44/81 (54%), Gaps = 4/81 (4%)

Query: 454 SDKNYKAEYEEDRGKGFFPQTITQEYEAIKKL-DQCKDHTYKVHPDKTK---FTQVTDSP 509
           S   YK ++EE +G+GF   T T E + +K+  +Q  +  Y    +KTK   FT V D P
Sbjct: 82  SQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDP 141

Query: 510 VLLQAQVNSKQLSDLNYKAKH 530
           V  + + N++ +SD  YK  H
Sbjct: 142 VTERVRKNTQVVSDAAYKGVH 162



 Score = 48.1 bits (113), Expect = 3e-04
 Identities = 35/127 (27%), Positives = 56/127 (44%), Gaps = 3/127 (2%)

Query: 2950 EQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKLANEEAK 3009
            +  L  NN     K+ Y  A    K     + DTPE +  +Q     S+  YK   EE+K
Sbjct: 36   KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94

Query: 3010 KKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKI 3069
             +G+ + +D   +   K +++ IS+ KY + + K  G   G   + DDP         ++
Sbjct: 95   GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152

Query: 3070 QSDREYK 3076
             SD  YK
Sbjct: 153  VSDAAYK 159



 Score = 48.1 bits (113), Expect = 3e-04
 Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 3/126 (2%)

Query: 2708 MVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKR 2767
            M L  NN      + Y  A    K +   + DTPE L  KQ     S+  YK   EE+K 
Sbjct: 37   MALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95

Query: 2768 KGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQ 2827
            +G+ +  D   ++  K +++  S  KY E + K  G   G   + DDP         ++ 
Sbjct: 96   RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVV 153

Query: 2828 SDREYK 2833
            SD  YK
Sbjct: 154  SDAAYK 159



 Score = 48.1 bits (113), Expect = 3e-04
 Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 9/127 (7%)

Query: 5837 KKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGH-YHTIPDNLEQLHLKEATE 5895
            K+    V D  E+L +      S+L S  +YK+ +E+SKG  +  + D  E   LK   E
Sbjct: 59   KQSFTTVADTPENLRLKQ---QSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQE 115

Query: 5896 LQSIVKYKEKYEKERGK---PMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTG 5952
              S VKY E +EK +G+   P++D   P     +++ Q+ S   Y+  +   ++     G
Sbjct: 116  QISNVKYHEDFEKTKGRGFTPVVD--DPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPG 173

Query: 5953 LEVTPAL 5959
            + V P L
Sbjct: 174  IIVAPVL 180



 Score = 48.1 bits (113), Expect = 3e-04
 Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 2/99 (2%)

Query: 111 QPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAK-TICHVDEKAKDIEHAKKVSQQVSK 169
           Q + +  DTPE  R+K+  +  S+VKY+ D + +K     +     +++  K+  +Q+S 
Sbjct: 60  QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISN 119

Query: 170 VLYKQNWEDTKDKYLLP-PDAPELVQAVKNTAMFSKKLY 207
           V Y +++E TK +   P  D P   +  KNT + S   Y
Sbjct: 120 VKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158



 Score = 47.8 bits (112), Expect = 4e-04
 Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 11/153 (7%)

Query: 169 KVLYKQNWEDTKDKY----LLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDS 224
           KV+Y     +  DKY        +  ++   + N   + KK Y       K  F    D+
Sbjct: 10  KVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADT 68

Query: 225 PELRRVAQAQKALSDVAYKKGLAEQQAQ-FTPLADPPDIEFAKKVTNQVSKQKYKEDYEN 283
           PE  R+ Q  +  S V YK+   E + + F+ + D P+++  K+   Q+S  KY ED+E 
Sbjct: 69  PENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE- 127

Query: 284 KIKGKWSETPCFE---VANARMNADNISTRKYQ 313
           K KG+   TP  +       R N   +S   Y+
Sbjct: 128 KTKGR-GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 47.8 bits (112), Expect = 4e-04
 Identities = 37/127 (29%), Positives = 54/127 (42%), Gaps = 3/127 (2%)

Query: 3436 EQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESK 3495
            +  L  NN     K+ Y  A    K++   + DTPE +  K      S   YK   EESK
Sbjct: 36   KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94

Query: 3496 KEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKI 3555
              G+ +  D   +Q  K +++  S+ KY E + K  G   G   + DDP         ++
Sbjct: 95   GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152

Query: 3556 QSDREYK 3562
             SD  YK
Sbjct: 153  VSDAAYK 159



 Score = 47.0 bits (110), Expect = 6e-04
 Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 4/96 (4%)

Query: 686 EDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKL-DQCKDHTYKVHP 744
           + P +    + +   S   YK ++EE KG+ +   T T E + +K+  +Q  +  Y    
Sbjct: 67  DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126

Query: 745 DKTK---FTAVTDSPVLLQAQLNTKQLSDLNYKAKH 777
           +KTK   FT V D PV  + + NT+ +SD  YK  H
Sbjct: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162



 Score = 47.0 bits (110), Expect = 6e-04
 Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 3/87 (3%)

Query: 1077 KAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSK 1136
            K   +  S V+YK+D+E++KG+  GF  + D P+L       +  S+ +Y +D+EKTK +
Sbjct: 75   KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132

Query: 1137 YNTP-HDMFNVVAAKKAQDVVSNVNYK 1162
              TP  D       +K   VVS+  YK
Sbjct: 133  GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 46.6 bits (109), Expect = 8e-04
 Identities = 30/95 (31%), Positives = 52/95 (54%), Gaps = 2/95 (2%)

Query: 4613 VWDTPQILHAKKSYDLQSQLQYTAAGKENL-QNYNLVTDTPLYVTAVQSGINASEVKYKE 4671
            V DTP+ L  K+  +LQSQ++Y    +E+  + +++VTDTP      ++    S VKY E
Sbjct: 65   VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE 124

Query: 4672 NYHQIKDK-YTTVLETVDYDRTRNLKNLYSSNLYK 4705
            ++ + K + +T V++    +R R    + S   YK
Sbjct: 125  DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 46.2 bits (108), Expect = 0.001
 Identities = 45/159 (28%), Positives = 68/159 (42%), Gaps = 10/159 (6%)

Query: 5513 KEVYQRNKSNCTIE---PDAVHIKAAKDAYKVNTNLDYKKQYEAN----KAHWKWTPDRP 5565
            K VY   K NC  +       H +  K A  +N    Y+K+   N    K  +    D P
Sbjct: 10   KVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTP 69

Query: 5566 DFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIE-SDLKYKEKHVKE 5624
            + L+  + S  QS  +YK D E  KG   S+  D   +  L+ T  + S++KY E   K 
Sbjct: 70   ENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT 129

Query: 5625 RGTCHA-VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQ 5662
            +G     V D P     +  + +VS+  YK  V  H+ +
Sbjct: 130  KGRGFTPVVDDPVTERVRKNTQVVSDAAYKG-VHPHIVE 167



 Score = 46.2 bits (108), Expect = 0.001
 Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 3/127 (2%)

Query: 3193 EQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAK 3252
            +  L  NN     K+ Y  A    K     + DTPE +  +Q     S+  Y++  EE+K
Sbjct: 36   KMALNMNNYKGYEKKPYCNA-HYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK 94

Query: 3253 KEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKV 3312
              G+ + +D   +   K +++  S+ KY E + K  G   G   V DDP         +V
Sbjct: 95   GRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQV 152

Query: 3313 QSDREYK 3319
             SD  YK
Sbjct: 153  VSDAAYK 159



 Score = 46.2 bits (108), Expect = 0.001
 Identities = 30/107 (28%), Positives = 55/107 (51%), Gaps = 5/107 (4%)

Query: 1160 NYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGW-IPIGSLDVEKVKK 1218
            N  +    +T + D  +    K   ++QS   YK D+    KG G+ I   + +++++K+
Sbjct: 54   NAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEE-SKGRGFSIVTDTPELQRLKR 112

Query: 1219 AGDALNEKKYRQHPDTLK---FTSIVDSPVMVQAKQNTKQVSDILYK 1262
              + ++  KY +  +  K   FT +VD PV  + ++NT+ VSD  YK
Sbjct: 113  TQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 46.2 bits (108), Expect = 0.001
 Identities = 41/165 (24%), Positives = 75/165 (45%), Gaps = 8/165 (4%)

Query: 5631 VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYK 5690
            V DTP+ L  K  S L S+ KYK   ++   +G ++ + +T +   +K   + +S+  Y 
Sbjct: 65   VADTPENLRLKQQSELQSQVKYKRDFEESKGRG-FSIVTDTPELQRLKRTQEQISNVKYH 123

Query: 5691 KKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKA-- 5748
            + F K KG+  ++ +++ P  +   +  +  SD AY+     + H   +  RP I  A  
Sbjct: 124  EDFEKTKGR-GFTPVVDDPVTERVRKNTQVVSDAAYK---GVHPHIVEMDRRPGIIVAPV 179

Query: 5749 -TQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQ 5792
               A +Q+    Y   H+   S   SM   P++   +     S+Q
Sbjct: 180  LPGAYQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQ 224



 Score = 45.8 bits (107), Expect = 0.001
 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 5/113 (4%)

Query: 4966 DTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELY 5025
            DTP    +K    + S  KYK  +E +K  G+++         ++R     S   Y E +
Sbjct: 67   DTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126

Query: 5026 HKLKDKIHT-TPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVI 5077
             K K +  T   D P   +V+K  + VS+  YK     +  H++ +   P +I
Sbjct: 127  EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKG----VHPHIVEMDRRPGII 175



 Score = 44.3 bits (103), Expect = 0.004
 Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 2/101 (1%)

Query: 3914 YTSIVDTPEVVLAKSNAENISIPKYREVWDKDK-TSIHIMPDTPEINLARANALNVSNKL 3972
            +T++ DTPE +  K  +E  S  KY+  +++ K     I+ DTPE+   +     +SN  
Sbjct: 62   FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 3973 YREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDH 4012
            Y E +++ K  G    +D    +  + + ++ SD  YK  H
Sbjct: 122  YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162



 Score = 43.9 bits (102), Expect = 0.005
 Identities = 27/102 (26%), Positives = 52/102 (50%), Gaps = 4/102 (3%)

Query: 3598 HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGW-VPIGSVEVEKVKRAGEI 3656
            +P   +T + D  + ++ ++  +LQS   YK D E  +G G+ +   + E++++KR  E 
Sbjct: 57   YPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQ 116

Query: 3657 LSDRKYRQPADQLK---FTCITDTPEIVLAKNNALTMSKHLY 3695
            +S+ KY +  ++ K   FT + D P     + N   +S   Y
Sbjct: 117  ISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158



 Score = 43.5 bits (101), Expect = 0.007
 Identities = 40/171 (23%), Positives = 69/171 (40%), Gaps = 19/171 (11%)

Query: 4858 VWDTPEILHAKHAYDLRDDIKYKAHMLKTRN-DYKLVTDTPVYVQAVKSGKQLSDAVYHY 4916
            V DTPE L  K   +L+  +KYK    +++   + +VTDTP   +  ++ +Q+S+  YH 
Sbjct: 65   VADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHE 124

Query: 4917 DYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDT 4976
            D+  +      P       +R     ++ S   YK             G  PH   +   
Sbjct: 125  DFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK-------------GVHPHIVEMDRR 171

Query: 4977 RYMSSYFKYKEAYE--HTKAYGYTLGPKDVPFVHVRRVNNVTSERLYRELY 5025
              +        AY+  H++ YGY           +R + +  + R YR +Y
Sbjct: 172  PGIIVAPVLPGAYQQSHSQGYGYM---HQTSVSSMRSMQHSPNLRTYRAMY 219



 Score = 43.1 bits (100), Expect = 0.009
 Identities = 29/111 (26%), Positives = 52/111 (46%), Gaps = 6/111 (5%)

Query: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSK-YNTPHDMFNVV 1147
            KK Y  A      F ++ D P+ +     +++QS  +YK+D+E++K + ++   D   + 
Sbjct: 49   KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108

Query: 1148 AAKKAQDVVSNVNYKHSLHH-----YTYLPDAMDLELSKNMMQIQSDNVYK 1193
              K+ Q+ +SNV Y           +T + D    E  +   Q+ SD  YK
Sbjct: 109  RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 43.1 bits (100), Expect = 0.009
 Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 2/103 (1%)

Query: 2488 KTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIAS 2547
            K     + DTP+ +  K      S   Y+  +EE K +G+ +  D   ++  K ++E  S
Sbjct: 59   KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 2548 EYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYK 2590
              KY E F K  G   G   + DDP         ++ SD  YK
Sbjct: 119  NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 43.1 bits (100), Expect = 0.009
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 2/102 (1%)

Query: 4155 NFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSK--YTLTETPLLHTAQEAARILDQY 4212
            +FT V D  + +  KQ  E+   +KY++D+  +K +    +T+TP L   +     +   
Sbjct: 61   SFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNV 120

Query: 4213 LYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEH 4254
             Y E +E+ K  G+    D            V S+  YK  H
Sbjct: 121  KYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVH 162



 Score = 42.7 bits (99), Expect = 0.012
 Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 21/138 (15%)

Query: 2029 KLSLEESKKKGYDLRP---------------DAIPIKAAKASRDIASDYKYKYNYEKGKG 2073
            K++L  +  KGY+ +P               D       K   ++ S  KYK ++E+ KG
Sbjct: 36   KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95

Query: 2074 KMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPA--DMLSVTAAKDAQAN 2131
            +  GF  + D P+L    +  +  S+ +Y +++E TK    TP   D ++    K+ Q  
Sbjct: 96   R--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV- 152

Query: 2132 ITNTNYKHLIHKYILLPD 2149
            +++  YK  +H +I+  D
Sbjct: 153  VSDAAYKG-VHPHIVEMD 169



 Score = 42.7 bits (99), Expect = 0.012
 Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 1/98 (1%)

Query: 253 FTPLADPPDIEFAKKVTNQVSKQKYKEDYE-NKIKGKWSETPCFEVANARMNADNISTRK 311
           FT +AD P+    K+ +   S+ KYK D+E +K +G    T   E+   +   + IS  K
Sbjct: 62  FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 312 YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYK 349
           Y EDFE  K + +    + P  +  +K     S   YK
Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 42.7 bits (99), Expect = 0.012
 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 5/99 (5%)

Query: 937  KKAYALQSDVEYKADYNSWMKGCGW-VPFGSLEMEKAKRASDILNEKKYRQHPDTLK--- 992
            K+   LQS V+YK D+    KG G+ +   + E+++ KR  + ++  KY +  +  K   
Sbjct: 75   KQQSELQSQVKYKRDFEE-SKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRG 133

Query: 993  FTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLP 1031
            FT + D P+T + + N    SD AYK     I+     P
Sbjct: 134  FTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRP 172



 Score = 42.4 bits (98), Expect = 0.016
 Identities = 35/142 (24%), Positives = 54/142 (38%), Gaps = 14/142 (9%)

Query: 955  WMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHP------DTLKFTSIEDAPITVQSKIN 1008
            W KGC          E  K A ++ N K Y + P          FT++ D P  ++ K  
Sbjct: 25   WHKGC-------FHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQ 77

Query: 1009 QAQRSDIAYKAKGEEIIHK-YNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLR 1067
               +S + YK   EE   + +++  D P+  + K     IS   Y  D +    +G+   
Sbjct: 78   SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPV 137

Query: 1068 TDAIPIRAAKAARQAASDVQYK 1089
             D       +   Q  SD  YK
Sbjct: 138  VDDPVTERVRKNTQVVSDAAYK 159



 Score = 42.0 bits (97), Expect = 0.020
 Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 2/92 (2%)

Query: 5073 TPQVIHCRYVGDITSDIKYKEDLQVLKGFG-CFLYDTPDMVRSRHLRKLWSNYLYTDKAR 5131
            TP+ +  +   ++ S +KYK D +  KG G   + DTP++ R +  ++  SN  Y +   
Sbjct: 68   TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127

Query: 5132 KMRDK-YKVVLDTPEYRKVQELKTHLSELVYR 5162
            K + + +  V+D P   +V++    +S+  Y+
Sbjct: 128  KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 41.6 bits (96), Expect = 0.027
 Identities = 29/107 (27%), Positives = 55/107 (51%), Gaps = 8/107 (7%)

Query: 571 KKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQ 630
           + F    D    L  K  ++  S V YK+D+E++KG+  G   + D P++    +  +  
Sbjct: 60  QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117

Query: 631 SDRLYKENYEKTKAKS----MNYCETPKYQLDTQLKNFSEARYKDLY 673
           S+  Y E++EKTK +     ++   T + + +TQ+   S+A YK ++
Sbjct: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV--VSDAAYKGVH 162



 Score = 41.2 bits (95), Expect = 0.035
 Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 6/111 (5%)

Query: 1577 KEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK-YHTPLDMVSVT 1635
            K+ Y  A   +  F ++ D P+ +     +++QS  +YK+ +E SK + +    D   + 
Sbjct: 49   KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108

Query: 1636 AAKKSQEVATNANYRQSYHH-----YTLLPDALNVEHSRNAMQIQSDNLYK 1681
              K++QE  +N  Y + +       +T + D    E  R   Q+ SD  YK
Sbjct: 109  RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 40.8 bits (94), Expect = 0.046
 Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 1/98 (1%)

Query: 3428 FTSITDTPEQVLAKNNALNMNKRLYTEAWDNDK-KTIHVMPDTPEIMLAKLNRINYSDKL 3486
            FT++ DTPE +  K  +   ++  Y   ++  K +   ++ DTPE+   K  +   S+  
Sbjct: 62   FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 3487 YKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYK 3524
            Y    E++K  G+   +D    +  + +  + SD  YK
Sbjct: 122  YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 4/100 (4%)

Query: 3846 WTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGW-MPQGSPEVLRVKNAQNIFCDSV 3904
            +T + D  + ++ K+  +LQS   YK D E  +G G+ +   +PE+ R+K  Q    +  
Sbjct: 62   FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 3905 YRTPVVNLK---YTSIVDTPEVVLAKSNAENISIPKYREV 3941
            Y       K   +T +VD P     + N + +S   Y+ V
Sbjct: 122  YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGV 161



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 4/98 (4%)

Query: 2388 WTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPL-GSLEAEKNKRASEIISEKK 2446
            +T + D  + ++ K+  ELQS+  YK D E  +G G+S +  + E ++ KR  E IS  K
Sbjct: 62   FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 2447 YRQPPDRNK---FTSIPDAMDIVLAKTNAKNRSDRLYR 2481
            Y +  ++ K   FT + D       + N +  SD  Y+
Sbjct: 122  YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 39.7 bits (91), Expect = 0.10
 Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 4/102 (3%)

Query: 3355 HPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGW-VPIDSLEVVRAKRAGEL 3413
            +P   +  + D  + +  ++  +LQS   YK D E  KG G+ +  D+ E+ R KR  E 
Sbjct: 57   YPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQ 116

Query: 3414 LSDTIYRQRPETLK---FTSITDTPEQVLAKNNALNMNKRLY 3452
            +S+  Y +  E  K   FT + D P     + N   ++   Y
Sbjct: 117  ISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAY 158



 Score = 39.3 bits (90), Expect = 0.13
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 6/111 (5%)

Query: 1821 KKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSK-TSFHTPVDMLSVV 1879
            KK Y  A      F ++ D P+ +   Q +++QS  +YK+ +E+SK   F    D   + 
Sbjct: 49   KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108

Query: 1880 AAKKSQEVATNANYRNVIHT-----YNMLPDAMSFELAKNMMQIQSDNQYK 1925
              K++QE  +N  Y           +  + D    E  +   Q+ SD  YK
Sbjct: 109  RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 39.3 bits (90), Expect = 0.13
 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 3/87 (3%)

Query: 2297 KASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTK 2356
            K   ++ S  KYK+ + +  G   GF  + D P+L       +  S  +Y +DFEK K +
Sbjct: 75   KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132

Query: 2357 -FSSPVDMLGVVLAKKCQELVSDVDYK 2382
             F+  VD       +K  ++VSD  YK
Sbjct: 133  GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 38.1 bits (87), Expect = 0.30
 Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 6/111 (5%)

Query: 1333 KEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTK-TSYHTPGDMVSIT 1391
            K+ Y  +      F ++ D P+ +     ++LQS  +YK+++E +K   +    D   + 
Sbjct: 49   KKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ 108

Query: 1392 AAKMAQDVATNVNYKQPLHH-----YTYLPDAMSLEHTRNVNQIQSDNVYK 1437
              K  Q+  +NV Y +         +T + D    E  R   Q+ SD  YK
Sbjct: 109  RLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 38.1 bits (87), Expect = 0.30
 Identities = 23/98 (23%), Positives = 44/98 (44%), Gaps = 1/98 (1%)

Query: 3671 FTCITDTPEIVLAKNNALTMSKHLYTEAWDADK-TSIHVMPDTPDILLAKSNSANISQKL 3729
            FT + DTPE +  K  +   S+  Y   ++  K     ++ DTP++   K     IS   
Sbjct: 62   FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 3730 YTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYK 3767
            Y + ++++K + +    D    +  + +  + SD  YK
Sbjct: 122  YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 37.7 bits (86), Expect = 0.39
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 5778 PDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLK 5837
            P+    K+ ++L SQVKY+ +F++ KG+         +L + +K      S VKY  D +
Sbjct: 69   PENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQR-LKRTQEQISNVKYHEDFE 127

Query: 5838 KLH-KPVTDMKESLIMNHVLNTSQLASSYQYK 5868
            K   +  T + +  +   V   +Q+ S   YK
Sbjct: 128  KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 37.0 bits (84), Expect = 0.66
 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 4/98 (4%)

Query: 4088 WTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGW-MPNDSVSVNHAKHAADIFSEKK 4146
            +T + D  + ++ K+  ELQS   YK D E  +G G+ +  D+  +   K   +  S  K
Sbjct: 62   FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 4147 YRTKIETL---NFTPVDDRVDYVTAKQSGEILDDIKYR 4181
            Y    E      FTPV D       +++ +++ D  Y+
Sbjct: 122  YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 37.0 bits (84), Expect = 0.66
 Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 2540 KASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTK 2599
            K   E+ S+ KYK  F +  G   G   + D P++       +  S+ +Y +DFEK K +
Sbjct: 75   KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132

Query: 2600 -FSSPVDMLGVVLAKKCQTLVSDVDYK 2625
             F+  VD       +K   +VSD  YK
Sbjct: 133  GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 36.6 bits (83), Expect = 0.86
 Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 5/107 (4%)

Query: 3253 KEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKV 3312
            K+ +   +D    +  K   ++ S  KYK  + +  G   G   V D P++       + 
Sbjct: 59   KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQ 116

Query: 3313 QSDREYKKDFEKYKTRYSSP-VDMLGIVLAKKCQTLVSDVDYK--HP 3356
             S+ +Y +DFEK K R  +P VD       +K   +VSD  YK  HP
Sbjct: 117  ISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHP 163



 Score = 36.2 bits (82), Expect = 1.1
 Identities = 46/185 (24%), Positives = 78/185 (42%), Gaps = 12/185 (6%)

Query: 3997 KASREIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAK 4056
            K   E+ S  KYK D E+ KG     +T   + + R     +++ N + Y  D+ K K +
Sbjct: 75   KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQ-RLKRTQEQISNVK-YHEDFEKTKGR 132

Query: 4057 IQSPV--DMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQA---KKAYELQSDNV 4111
              +PV  D ++    KN+Q +VSD  Y+        M  +  +I A     AY+      
Sbjct: 133  GFTPVVDDPVTERVRKNTQ-VVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHSQG 191

Query: 4112 Y----KADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVT 4167
            Y    +  +  +R +   PN         ++A    E  +R     +N  P+DD   Y T
Sbjct: 192  YGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEVSFRDGDYIVNVQPIDDGWMYGT 251

Query: 4168 AKQSG 4172
             +++G
Sbjct: 252  VQRTG 256



 Score = 35.8 bits (81), Expect = 1.5
 Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 4643 QNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDK-YTTVLETVDYDRTRNLKNLYSS 4701
            Q++  V DTP  +   Q     S+VKYK ++ + K + ++ V +T +  R +  +   S+
Sbjct: 60   QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISN 119

Query: 4702 NLYKEAWDRVKATSY 4716
              Y E +++ K   +
Sbjct: 120  VKYHEDFEKTKGRGF 134



 Score = 35.8 bits (81), Expect = 1.5
 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 4/92 (4%)

Query: 3887 SPEVLRVKNAQNIFCDSVYRTPVVNLK---YTSIVDTPEVVLAKSNAENISIPKYREVWD 3943
            +PE LR+K    +     Y+      K   ++ + DTPE+   K   E IS  KY E ++
Sbjct: 68   TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127

Query: 3944 KDK-TSIHIMPDTPEINLARANALNVSNKLYR 3974
            K K      + D P     R N   VS+  Y+
Sbjct: 128  KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 35.4 bits (80), Expect = 1.9
 Identities = 27/113 (23%), Positives = 54/113 (47%), Gaps = 11/113 (9%)

Query: 4499 YEKQ---KGHY--LAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKAN-VHIPNDMMN 4552
            YEK+     HY   +   + + P  +      +++S + Y++ +E++K     I  D   
Sbjct: 47   YEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPE 106

Query: 4553 HVLAKRCQYILSDLEYRHYFHQ-----WTSLLEEPNVIRVRNAQEILSDNVYK 4600
                KR Q  +S+++Y   F +     +T ++++P   RVR   +++SD  YK
Sbjct: 107  LQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 35.4 bits (80), Expect = 1.9
 Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 6/98 (6%)

Query: 2322 FRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTK-FSSPVDMLGVVLAKKCQELVSDVD 2380
            F ++ D P+ +     +++QS+ +YK+DFE+ K + FS   D   +   K+ QE +S+V 
Sbjct: 62   FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 2381 Y-----KNYLHQWTCLPDQNDVVQAKKVYELQSENLYK 2413
            Y     K     +T + D     + +K  ++ S+  YK
Sbjct: 122  YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 35.4 bits (80), Expect = 1.9
 Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 2783 KASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTK 2842
            K   ++ S+ KYK  + +  G   G   + D P++       +  S+ +Y +DFEK K +
Sbjct: 75   KQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132

Query: 2843 -FSSPVDMLGVVLAKKCQTLVSDVDYK 2868
             F+  VD       +K   +VSD  YK
Sbjct: 133  GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 35.4 bits (80), Expect = 1.9
 Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 5/85 (5%)

Query: 4242 NDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINI 4301
            +++QS++KYK +  + KG   G   + D P+L   +   +  +   Y ED+ KTK +   
Sbjct: 78   SELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135

Query: 4302 PA--DMVSVLAAKQGQTLVSDIDYR 4324
            P   D V+    K  Q +VSD  Y+
Sbjct: 136  PVVDDPVTERVRKNTQ-VVSDAAYK 159



 Score = 34.3 bits (77), Expect = 4.3
 Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 2/98 (2%)

Query: 4192 TLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYK 4251
            T+ +TP     ++ + +  Q  YK  +E  K  G+ +  D           +  S +KY 
Sbjct: 64   TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123

Query: 4252 AEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYK 4289
             +  K KG   G   + DDP         Q+ ++  YK
Sbjct: 124  EDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 34.3 bits (77), Expect = 4.3
 Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 6/96 (6%)

Query: 4756 SVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMK-IHIVPDMVEMVTAKDSQKKVSEIDY- 4813
            +V D P   R  +  +L     Y+  +E++K +   IV D  E+   K +Q+++S + Y 
Sbjct: 64   TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123

Query: 4814 ----RLRLHEWICHPDLQVNDHVRKVTDQISDIVYK 4845
                + +   +    D  V + VRK T  +SD  YK
Sbjct: 124  EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 33.5 bits (75), Expect = 7.3
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 1/73 (1%)

Query: 3946 KTSIHIMPDTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIAS 4004
            K S   + DTPE    +  +   S   Y+  ++E K  G  +  D   +Q  K ++E  S
Sbjct: 59   KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 4005 DYKYKLDHEKQKG 4017
            + KY  D EK KG
Sbjct: 119  NVKYHEDFEKTKG 131



 Score = 33.5 bits (75), Expect = 7.3
 Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 5/108 (4%)

Query: 367 SENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYC-ETPKFKLDTVLQNFSSDKKYKDS 425
           ++ P+  +LK   +  S   YK ++E++K +  +   +TP+ +     Q   S+ KY + 
Sbjct: 66  ADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125

Query: 426 YLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEY----EEDRGKG 469
           + K     +    +DP      K T   SD  YK  +    E DR  G
Sbjct: 126 FEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPG 173



 Score = 33.1 bits (74), Expect = 9.5
 Identities = 24/104 (23%), Positives = 46/104 (44%), Gaps = 5/104 (4%)

Query: 4484 KHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKAN 4543
            K    + S++KYK  +E+ KG   +  ++ + P +      Q+  S + Y + +E TK  
Sbjct: 75   KQQSELQSQVKYKRDFEESKGRGFS--IVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132

Query: 4544 VHIP--NDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVI 4585
               P  +D +   + K  Q ++SD  Y+        +   P +I
Sbjct: 133  GFTPVVDDPVTERVRKNTQ-VVSDAAYKGVHPHIVEMDRRPGII 175


>gi|20357552 cortactin isoform a [Homo sapiens]
          Length = 550

 Score = 63.5 bits (153), Expect = 7e-09
 Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 13/123 (10%)

Query: 6546 ISGGEEKSEHS-EAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTTVSSI 6604
            +SG E +  +S EA D+  ++   G  +A    Y+ A   E P    +  +T        
Sbjct: 437  VSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESA---EAPGHYPAEDSTYD------ 487

Query: 6605 PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN 6664
              + +  G    A+YDY AA  DE+SF   D I N++ ID+GW  G  +  GR G+ PAN
Sbjct: 488  -EYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK--GRYGLFPAN 544

Query: 6665 YVE 6667
            YVE
Sbjct: 545  YVE 547


>gi|20357556 cortactin isoform b [Homo sapiens]
          Length = 513

 Score = 63.5 bits (153), Expect = 7e-09
 Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 13/123 (10%)

Query: 6546 ISGGEEKSEHS-EAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTTVSSI 6604
            +SG E +  +S EA D+  ++   G  +A    Y+ A   E P    +  +T        
Sbjct: 400  VSGTEPEPVYSMEAADYREASSQQGLAYATEAVYESA---EAPGHYPAEDSTYD------ 450

Query: 6605 PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN 6664
              + +  G    A+YDY AA  DE+SF   D I N++ ID+GW  G  +  GR G+ PAN
Sbjct: 451  -EYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK--GRYGLFPAN 507

Query: 6665 YVE 6667
            YVE
Sbjct: 508  YVE 510


>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
            sapiens]
          Length = 492

 Score = 60.1 bits (144), Expect = 7e-08
 Identities = 53/193 (27%), Positives = 82/193 (42%), Gaps = 24/193 (12%)

Query: 6499 RVWRTNPGSVFDYDPAEDNI--QSRSLHMINVQAQRRSREQSRSASALSISGGEEKSEHS 6556
            R +R+ P S+F+Y+P + +I    R   +      R       SAS  S      KSE +
Sbjct: 122  RKFRSEPRSIFEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPA 181

Query: 6557 EAP-----DHHLSTYSDGGV------------FAVST--AYKHAKTTELPQQRSSSVATQ 6597
              P     D   S  S G V            F  S+  +   AK  E P+  SS++   
Sbjct: 182  VGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDM 241

Query: 6598 -QTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTG 6656
             ++        P       +A+YD+ A  + E+SFK GD +  ++ ID+ W  G  +  G
Sbjct: 242  GRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHG 299

Query: 6657 RTGMLPANYVEAI 6669
            R G+ P +YVE +
Sbjct: 300  RVGIFPISYVEKL 312



 Score = 50.1 bits (118), Expect = 8e-05
 Identities = 21/58 (36%), Positives = 35/58 (60%)

Query: 6612 GKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            G+ F+A+Y+Y   + DE+  ++ D I  ++  D+GW  GT +RT   G  P NYV+ +
Sbjct: 435  GEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 492



 Score = 46.6 bits (109), Expect = 8e-04
 Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 1/65 (1%)

Query: 6605 PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN 6664
            P+ P   G+   A Y++ A    E+S + GD +I ++ +D+ W  G +  T R G+ P +
Sbjct: 326  PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVS 384

Query: 6665 YVEAI 6669
            YVE +
Sbjct: 385  YVEVV 389


>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
            sapiens]
          Length = 644

 Score = 60.1 bits (144), Expect = 7e-08
 Identities = 53/193 (27%), Positives = 82/193 (42%), Gaps = 24/193 (12%)

Query: 6499 RVWRTNPGSVFDYDPAEDNI--QSRSLHMINVQAQRRSREQSRSASALSISGGEEKSEHS 6556
            R +R+ P S+F+Y+P + +I    R   +      R       SAS  S      KSE +
Sbjct: 274  RKFRSEPRSIFEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPA 333

Query: 6557 EAP-----DHHLSTYSDGGV------------FAVST--AYKHAKTTELPQQRSSSVATQ 6597
              P     D   S  S G V            F  S+  +   AK  E P+  SS++   
Sbjct: 334  VGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKDRESPRSYSSTLTDM 393

Query: 6598 -QTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTG 6656
             ++        P       +A+YD+ A  + E+SFK GD +  ++ ID+ W  G  +  G
Sbjct: 394  GRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEG--EHHG 451

Query: 6657 RTGMLPANYVEAI 6669
            R G+ P +YVE +
Sbjct: 452  RVGIFPISYVEKL 464



 Score = 50.1 bits (118), Expect = 8e-05
 Identities = 21/58 (36%), Positives = 35/58 (60%)

Query: 6612 GKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            G+ F+A+Y+Y   + DE+  ++ D I  ++  D+GW  GT +RT   G  P NYV+ +
Sbjct: 587  GEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 644



 Score = 46.6 bits (109), Expect = 8e-04
 Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 1/65 (1%)

Query: 6605 PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN 6664
            P+ P   G+   A Y++ A    E+S + GD +I ++ +D+ W  G +  T R G+ P +
Sbjct: 478  PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVS 536

Query: 6665 YVEAI 6669
            YVE +
Sbjct: 537  YVEVV 541


>gi|19224660 protein kinase C and casein kinase substrate in neurons 3
            [Homo sapiens]
          Length = 424

 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 36/89 (40%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 6584 TELPQQRSSSVATQQTTVSSIPSHPSTA--GKIFRAMYDYMAADADEVSFKDGDAIINVQ 6641
            T  P Q   S  T Q    S    P  A  G   RA+YDY   +ADE+SF+ G+ ++ + 
Sbjct: 335  TAPPPQSPGSPGTGQDEEWSDEESPRKAATGVRVRALYDYAGQEADELSFRAGEELLKMS 394

Query: 6642 AIDE-GWMYGTVQRTGRTGMLPANYVEAI 6669
              DE GW  G +Q +GR G+ PANYVE +
Sbjct: 395  EEDEQGWCQGQLQ-SGRIGLYPANYVECV 422


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 57.8 bits (138), Expect = 4e-07
 Identities = 104/515 (20%), Positives = 216/515 (41%), Gaps = 58/515 (11%)

Query: 5675 VHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENL 5734
            +H+ E TK ++     K  +++  +    ++ E     H   +  K+ ++A         
Sbjct: 336  LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHET-LEMKEEEIAQL------- 387

Query: 5735 HYTTVADRPDIKKATQAAKQASEVEYRAKHR--KEGSHGLSMLGRPDIEMAKKAAKLSSQ 5792
                   R  IK+ T   ++  E + +++    +E    LS   + +    K  A++  Q
Sbjct: 388  -------RSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 440

Query: 5793 VKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLKKLHKPVTDMKESLIM 5852
            +K  E   +E+  +     + S++ + + D    +SE +  A L+KLH+     KE  + 
Sbjct: 441  IKTIEKTSEEERIS--LQQELSRVKQEVVDVMKKSSEEQI-AKLQKLHEKELARKEQELT 497

Query: 5853 NHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGK 5912
               L T +     Q K   EKS+  Y  I    EQ   +E+  L+ +   K+    E   
Sbjct: 498  KK-LQTREREFQEQMKVALEKSQSEYLKISQEKEQ---QESLALEELELQKKAILTESEN 553

Query: 5913 PMLDF--ETPTYIT------AKESQQMQSGKEYRKDYEESIKG-RNLTGLEVTPALLHVK 5963
             + D   E  TY T      +   + +Q  K   KD    ++  +N    E+T  ++  K
Sbjct: 554  KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEIT--VMVEK 611

Query: 5964 YATKIASEKEYRKDLE----ESIRGKGLTEMEDTPDMLRAKNATQILNEKEY-------- 6011
            + T++ S K  +  L     + ++ +  TEME   +    +  T +L +KE         
Sbjct: 612  HKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKET-LLKDKEIIFQAHIEE 670

Query: 6012 --KRDLE-LEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPE 6068
              ++ LE L+VK   L ++++E  + ++AR+  +    +   Q+ +M K    + +D  +
Sbjct: 671  MNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKM-KQELEAKMDEQK 729

Query: 6069 IIHAQQVKNLSSQKKYK----EDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLK 6124
              H QQV ++  + +      E A K       +L     + ++E+Q +   L  + D+K
Sbjct: 730  NHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENL--EADIK 787

Query: 6125 NSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVS 6159
             S+G++       ++ +  ++  +  +  Y+E ++
Sbjct: 788  RSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 822



 Score = 36.2 bits (82), Expect = 1.1
 Identities = 65/343 (18%), Positives = 136/343 (39%), Gaps = 46/343 (13%)

Query: 90  QKMQDLFSPNKYK------------EKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKY 137
           +K++DL    K K            E+ E+ KG   A T         K+   +  E+K 
Sbjct: 331 EKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAET---------KRQMHETLEMKE 381

Query: 138 RMDGDVAKTICHVDEKAKDIEHAKKVSQ-----QVSKVLYK-QNWEDTKDKYLLPPDAPE 191
                +   I  +  + +++   K+ S+     ++ K L   Q  E+ + K  L  +  E
Sbjct: 382 EEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRK--LKAEMDE 439

Query: 192 LVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQA 251
            ++ ++ T+   +    ++    K             ++A+ QK      ++K LA ++ 
Sbjct: 440 QIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL-----HEKELARKEQ 494

Query: 252 QFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRK 311
           + T      + EF +++  +V+ +K + +Y  KI  +  +     +    +    I T  
Sbjct: 495 ELTKKLQTREREFQEQM--KVALEKSQSEYL-KISQEKEQQESLALEELELQKKAILTES 551

Query: 312 YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKE-----DYEKNKGKADYNVLPA 366
            +    +++ +    +T   E + + +  +  +K + K+     + EKNK   +  V+  
Sbjct: 552 -ENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVE 610

Query: 367 SENPQLRQLKAAGDAL-SDKL--YKENYEKTKAKSINYCETPK 406
               +L  LK   DAL ++KL   K+ Y+    K    CE  K
Sbjct: 611 KHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEK 653


>gi|171906575 drebrin-like isoform c [Homo sapiens]
          Length = 439

 Score = 56.2 bits (134), Expect = 1e-06
 Identities = 30/61 (49%), Positives = 35/61 (57%), Gaps = 1/61 (1%)

Query: 6609 STAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEA 6668
            S  G   RA+YDY AAD  E+SF   + I  ++ IDEGW  G     G  GM PANYVE 
Sbjct: 379  SGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVEL 437

Query: 6669 I 6669
            I
Sbjct: 438  I 438


>gi|62198235 drebrin-like isoform b [Homo sapiens]
          Length = 430

 Score = 56.2 bits (134), Expect = 1e-06
 Identities = 30/61 (49%), Positives = 35/61 (57%), Gaps = 1/61 (1%)

Query: 6609 STAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEA 6668
            S  G   RA+YDY AAD  E+SF   + I  ++ IDEGW  G     G  GM PANYVE 
Sbjct: 370  SGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVEL 428

Query: 6669 I 6669
            I
Sbjct: 429  I 429


>gi|21361670 drebrin-like isoform a [Homo sapiens]
          Length = 431

 Score = 56.2 bits (134), Expect = 1e-06
 Identities = 30/61 (49%), Positives = 35/61 (57%), Gaps = 1/61 (1%)

Query: 6609 STAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEA 6668
            S  G   RA+YDY AAD  E+SF   + I  ++ IDEGW  G     G  GM PANYVE 
Sbjct: 371  SGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVEL 429

Query: 6669 I 6669
            I
Sbjct: 430  I 430


>gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo
            sapiens]
          Length = 671

 Score = 55.1 bits (131), Expect = 2e-06
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 13/99 (13%)

Query: 6584 TELPQQRSSSVATQQTTVSSI--PSHPSTAGKI-----------FRAMYDYMAADADEVS 6630
            T+ P+ ++ ++ T    +S    PSHP   G             +RAMY Y   + DE+ 
Sbjct: 573  TQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDELE 632

Query: 6631 FKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
             ++GD +  +Q  D+GW  G  +RT + G  P NYV  +
Sbjct: 633  LREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 671



 Score = 42.4 bits (98), Expect = 0.016
 Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 6613 KIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            K  R  +D+ A    E++ + GD +   + +D+ W+ G  +  GR G+ PANYVE +
Sbjct: 383  KAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEG--EHHGRLGIFPANYVEVL 437



 Score = 42.0 bits (97), Expect = 0.020
 Identities = 18/51 (35%), Positives = 30/51 (58%)

Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVE 6667
            A Y +      E+SF+ G+ I  ++ ++E W  G +  TGR G+ PA+YV+
Sbjct: 461  AQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQ 511


>gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo
            sapiens]
          Length = 329

 Score = 55.1 bits (131), Expect = 2e-06
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 13/99 (13%)

Query: 6584 TELPQQRSSSVATQQTTVSSI--PSHPSTAGKI-----------FRAMYDYMAADADEVS 6630
            T+ P+ ++ ++ T    +S    PSHP   G             +RAMY Y   + DE+ 
Sbjct: 231  TQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDELE 290

Query: 6631 FKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
             ++GD +  +Q  D+GW  G  +RT + G  P NYV  +
Sbjct: 291  LREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV 329



 Score = 42.4 bits (98), Expect = 0.016
 Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 2/57 (3%)

Query: 6613 KIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            K  R  +D+ A    E++ + GD +   + +D+ W+ G  +  GR G+ PANYVE +
Sbjct: 41   KAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEG--EHHGRLGIFPANYVEVL 95



 Score = 42.0 bits (97), Expect = 0.020
 Identities = 18/51 (35%), Positives = 30/51 (58%)

Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVE 6667
            A Y +      E+SF+ G+ I  ++ ++E W  G +  TGR G+ PA+YV+
Sbjct: 119  AQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQ 169


>gi|78000167 sorbin and SH3 domain containing 1 isoform 5 [Homo
            sapiens]
          Length = 905

 Score = 54.7 bits (130), Expect = 3e-06
 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 2/87 (2%)

Query: 6585 ELPQQRSSSVATQQTTVSSIPSHPSTAGKIF--RAMYDYMAADADEVSFKDGDAIINVQA 6642
            +L +   S V  Q       P    T+  +F  +A+Y Y+  + DE+  +DGD +  ++ 
Sbjct: 817  DLTESEKSYVQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEK 876

Query: 6643 IDEGWMYGTVQRTGRTGMLPANYVEAI 6669
             D+GW  GT +RT + G  P NYV+ +
Sbjct: 877  CDDGWFVGTSRRTKQFGTFPGNYVKPL 903



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 17/53 (32%), Positives = 29/53 (54%)

Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            A +++      E+SF+ G+ I  ++ +DE W  G +  T R G+ P  YV+ I
Sbjct: 725  AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 777



 Score = 37.7 bits (86), Expect = 0.39
 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 6616 RAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            RA +D+ A    E+  + GD +   + ID+ W  G  +  GR G+ P  Y+E +
Sbjct: 650  RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 701


>gi|24308229 protein kinase C and casein kinase substrate in neurons 1
            [Homo sapiens]
          Length = 444

 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 40/140 (28%), Positives = 66/140 (47%), Gaps = 13/140 (9%)

Query: 6533 RSREQSRSASALSISGGEEKSEH-SEAPDH-HLSTYSDGGVFAVSTAYKHAKTTELPQQR 6590
            +  +Q + A  ++++      E  S+A D   +S+Y  G  +A   +           + 
Sbjct: 315  KKEKQPKKAEGVALTNATGAVESTSQAGDRGSVSSYDRGQPYATEWS---------DDES 365

Query: 6591 SSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDE-GWMY 6649
             +     +T   + P    + G   RA+YDY   + DE+SFK GD +  +   DE GW  
Sbjct: 366  GNPFGGSETNGGANPFEDDSKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCR 425

Query: 6650 GTVQRTGRTGMLPANYVEAI 6669
            G +  +G+ G+ PANYVEAI
Sbjct: 426  GRLD-SGQLGLYPANYVEAI 444


>gi|78000171 sorbin and SH3 domain containing 1 isoform 7 [Homo
            sapiens]
          Length = 740

 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%)

Query: 6590 RSSSVATQQTTVSS---IPSHPSTAGKIF--RAMYDYMAADADEVSFKDGDAIINVQAID 6644
            RS++ + QQ         P    T+  +F  +A+Y Y+  + DE+  +DGD +  ++  D
Sbjct: 654  RSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCD 713

Query: 6645 EGWMYGTVQRTGRTGMLPANYVEAI 6669
            +GW  GT +RT + G  P NYV+ +
Sbjct: 714  DGWFVGTSRRTKQFGTFPGNYVKPL 738



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 17/53 (32%), Positives = 29/53 (54%)

Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            A +++      E+SF+ G+ I  ++ +DE W  G +  T R G+ P  YV+ I
Sbjct: 580  AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 632



 Score = 37.7 bits (86), Expect = 0.39
 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 6616 RAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            RA +D+ A    E+  + GD +   + ID+ W  G  +  GR G+ P  Y+E +
Sbjct: 505  RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 556


>gi|78000169 sorbin and SH3 domain containing 1 isoform 6 [Homo
            sapiens]
          Length = 781

 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%)

Query: 6590 RSSSVATQQTTVSS---IPSHPSTAGKIF--RAMYDYMAADADEVSFKDGDAIINVQAID 6644
            RS++ + QQ         P    T+  +F  +A+Y Y+  + DE+  +DGD +  ++  D
Sbjct: 695  RSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCD 754

Query: 6645 EGWMYGTVQRTGRTGMLPANYVEAI 6669
            +GW  GT +RT + G  P NYV+ +
Sbjct: 755  DGWFVGTSRRTKQFGTFPGNYVKPL 779



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 17/53 (32%), Positives = 29/53 (54%)

Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            A +++      E+SF+ G+ I  ++ +DE W  G +  T R G+ P  YV+ I
Sbjct: 621  AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 673



 Score = 37.7 bits (86), Expect = 0.39
 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 6616 RAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            RA +D+ A    E+  + GD +   + ID+ W  G  +  GR G+ P  Y+E +
Sbjct: 546  RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 597


>gi|7661700 sorbin and SH3 domain containing 1 isoform 2 [Homo
            sapiens]
          Length = 816

 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%)

Query: 6590 RSSSVATQQTTVSS---IPSHPSTAGKIF--RAMYDYMAADADEVSFKDGDAIINVQAID 6644
            RS++ + QQ         P    T+  +F  +A+Y Y+  + DE+  +DGD +  ++  D
Sbjct: 730  RSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCD 789

Query: 6645 EGWMYGTVQRTGRTGMLPANYVEAI 6669
            +GW  GT +RT + G  P NYV+ +
Sbjct: 790  DGWFVGTSRRTKQFGTFPGNYVKPL 814



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 17/53 (32%), Positives = 29/53 (54%)

Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            A +++      E+SF+ G+ I  ++ +DE W  G +  T R G+ P  YV+ I
Sbjct: 656  AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 708



 Score = 38.9 bits (89), Expect = 0.17
 Identities = 40/209 (19%), Positives = 79/209 (37%), Gaps = 25/209 (11%)

Query: 6481 VEMEQKRND-QDQETITGLRVWRTNPGSVFDYDPAEDNIQSRS----------------- 6522
            ++   +RND +  +     R +R  P S+++Y P + ++ +                   
Sbjct: 429  LKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSSAISPTPEISSETP 488

Query: 6523 --LHMINVQAQRRSREQSRSASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKH 6580
              ++  N  A +R  E   +   L+    E +   S      +      G+   S++   
Sbjct: 489  GYIYSSNFHAVKR--ESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSAS- 545

Query: 6581 AKTTELPQQRSSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINV 6640
             K +E P+    +   + T       H     +  RA +D+ A    E+  + GD +   
Sbjct: 546  TKDSESPRHFIPADYLESTEEFIRRRHDDKEMRPARAKFDFKAQTLKELPLQKGDIVYIY 605

Query: 6641 QAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            + ID+ W  G  +  GR G+ P  Y+E +
Sbjct: 606  KQIDQNWYEG--EHHGRVGIFPRTYIELL 632


>gi|78000160 sorbin and SH3 domain containing 1 isoform 1 [Homo
            sapiens]
          Length = 684

 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 5/85 (5%)

Query: 6590 RSSSVATQQTTVSS---IPSHPSTAGKIF--RAMYDYMAADADEVSFKDGDAIINVQAID 6644
            RS++ + QQ         P    T+  +F  +A+Y Y+  + DE+  +DGD +  ++  D
Sbjct: 598  RSATASPQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCD 657

Query: 6645 EGWMYGTVQRTGRTGMLPANYVEAI 6669
            +GW  GT +RT + G  P NYV+ +
Sbjct: 658  DGWFVGTSRRTKQFGTFPGNYVKPL 682



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 17/53 (32%), Positives = 29/53 (54%)

Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            A +++      E+SF+ G+ I  ++ +DE W  G +  T R G+ P  YV+ I
Sbjct: 524  AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 576



 Score = 38.9 bits (89), Expect = 0.17
 Identities = 40/209 (19%), Positives = 79/209 (37%), Gaps = 25/209 (11%)

Query: 6481 VEMEQKRND-QDQETITGLRVWRTNPGSVFDYDPAEDNIQSRS----------------- 6522
            ++   +RND +  +     R +R  P S+++Y P + ++ +                   
Sbjct: 297  LKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSSAISPTPEISSETP 356

Query: 6523 --LHMINVQAQRRSREQSRSASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKH 6580
              ++  N  A +R  E   +   L+    E +   S      +      G+   S++   
Sbjct: 357  GYIYSSNFHAVKR--ESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSAS- 413

Query: 6581 AKTTELPQQRSSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINV 6640
             K +E P+    +   + T       H     +  RA +D+ A    E+  + GD +   
Sbjct: 414  TKDSESPRHFIPADYLESTEEFIRRRHDDKEMRPARAKFDFKAQTLKELPLQKGDIVYIY 473

Query: 6641 QAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            + ID+ W  G  +  GR G+ P  Y+E +
Sbjct: 474  KQIDQNWYEG--EHHGRVGIFPRTYIELL 500


>gi|148747351 protein kinase C and casein kinase substrate in neurons
            2 [Homo sapiens]
          Length = 486

 Score = 53.9 bits (128), Expect = 5e-06
 Identities = 45/148 (30%), Positives = 70/148 (47%), Gaps = 17/148 (11%)

Query: 6538 SRSASALSISGGEEKSEHSEAP-------DHHLSTYSDGGVFAVSTAYKHAKTTELPQQR 6590
            S+ +S L++     +S  S++        D   ST S+           + KT   P   
Sbjct: 339  SKPSSTLNVPSNPAQSAQSQSSYNPFEDEDDTGSTVSEKDDTKAKNVSSYEKTQSYPTDW 398

Query: 6591 SSSVATQ--QTTVSSIPSHP----STAGKIFR--AMYDYMAADADEVSFKDGDAIINVQA 6642
            S   +     +T ++  S+P    +T+G   R  A+YDY   + DE+SFK GD +  ++ 
Sbjct: 399  SDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMED 458

Query: 6643 IDE-GWMYGTVQRTGRTGMLPANYVEAI 6669
             DE GW  G +   G+ G+ PANYVEAI
Sbjct: 459  EDEQGWCKGRLD-NGQVGLYPANYVEAI 485



 Score = 35.8 bits (81), Expect = 1.5
 Identities = 55/211 (26%), Positives = 89/211 (42%), Gaps = 23/211 (10%)

Query: 5783 AKKAAKLSSQVKYR-ENFDKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLKKLHK 5841
            A++ ++L  +VK    N D EK K  +      Q+    K+     +E  ++   K   K
Sbjct: 90   AERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKE--AEDGFRKAQKPWAK 147

Query: 5842 PVTDMKESLIMNHVL-NTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIV 5900
             + +++ +   +H      +LA S +   K + S       P+ L++L  K     Q ++
Sbjct: 148  KLKEVEAAKKAHHAACKEEKLAISREANSKADPSLN-----PEQLKKLQDKIEKCKQDVL 202

Query: 5901 KYKEKYEKERGKPMLDFETPTYITAKES--QQMQSGKEYRKDYEESIKGRNLTGLEVTPA 5958
            K KEKYEK   +  LD  TP Y+   E   +Q Q  +E R  +   +       LEV   
Sbjct: 203  KTKEKYEKSLKE--LDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVL------LEVQKH 254

Query: 5959 LLHVKYATKIASEKEYRKDLEESIRGKGLTE 5989
            L      + +A  K    DLE+SIR     E
Sbjct: 255  L----DLSNVAGYKAIYHDLEQSIRAADAVE 281


>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
            sapiens]
          Length = 661

 Score = 53.5 bits (127), Expect = 7e-06
 Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 43/212 (20%)

Query: 6499 RVWRTNPGSVFDYDPAE---------------DNIQSRSLHMINVQAQRRS---REQSRS 6540
            R +R+ P S+F+Y+P +               D +Q  S  + N  +  +S   R   R 
Sbjct: 272  RKFRSEPRSIFEYEPGKSSILQHERPPPKKPLDYVQDHSSGVFNEASLYQSSIDRSLERP 331

Query: 6541 ASALSISGGEEKSEHSEAP--------DHHLSTYSDGGV------------FAVST--AY 6578
             S+ S++    K   SE          D   S  S G V            F  S+  + 
Sbjct: 332  MSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSP 391

Query: 6579 KHAKTTELPQQRSSSVATQ-QTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAI 6637
              AK  E P+  SS++    ++        P       +A+YD+ A  + E+SFK GD +
Sbjct: 392  SRAKDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTV 451

Query: 6638 INVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
              ++ ID+ W  G  +  GR G+ P +YVE +
Sbjct: 452  YILRKIDQNWYEG--EHHGRVGIFPISYVEKL 481



 Score = 50.1 bits (118), Expect = 8e-05
 Identities = 21/58 (36%), Positives = 35/58 (60%)

Query: 6612 GKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            G+ F+A+Y+Y   + DE+  ++ D I  ++  D+GW  GT +RT   G  P NYV+ +
Sbjct: 604  GEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 661



 Score = 46.6 bits (109), Expect = 8e-04
 Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 1/65 (1%)

Query: 6605 PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN 6664
            P+ P   G+   A Y++ A    E+S + GD +I ++ +D+ W  G +  T R G+ P +
Sbjct: 495  PAQPGEIGEAI-AKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVS 553

Query: 6665 YVEAI 6669
            YVE +
Sbjct: 554  YVEVV 558


>gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo
            sapiens]
          Length = 1151

 Score = 53.1 bits (126), Expect = 9e-06
 Identities = 26/79 (32%), Positives = 42/79 (53%)

Query: 6591 SSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYG 6650
            S     QQ  V+   S  S     ++A+Y Y+  + DE+  +DGD +  ++  D+GW  G
Sbjct: 1071 SQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVG 1130

Query: 6651 TVQRTGRTGMLPANYVEAI 6669
            T +RT + G  P NYV+ +
Sbjct: 1131 TSRRTKQFGTFPGNYVKPL 1149



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 17/53 (32%), Positives = 29/53 (54%)

Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            A +++      E+SF+ G+ I  ++ +DE W  G +  T R G+ P  YV+ I
Sbjct: 896  AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 948



 Score = 37.7 bits (86), Expect = 0.39
 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 6616 RAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            RA +D+ A    E+  + GD +   + ID+ W  G  +  GR G+ P  Y+E +
Sbjct: 821  RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 872


>gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo
            sapiens]
          Length = 1292

 Score = 53.1 bits (126), Expect = 9e-06
 Identities = 26/79 (32%), Positives = 42/79 (53%)

Query: 6591 SSSVATQQTTVSSIPSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYG 6650
            S     QQ  V+   S  S     ++A+Y Y+  + DE+  +DGD +  ++  D+GW  G
Sbjct: 1212 SQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVG 1271

Query: 6651 TVQRTGRTGMLPANYVEAI 6669
            T +RT + G  P NYV+ +
Sbjct: 1272 TSRRTKQFGTFPGNYVKPL 1290



 Score = 40.0 bits (92), Expect = 0.078
 Identities = 17/53 (32%), Positives = 29/53 (54%)

Query: 6617 AMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            A +++      E+SF+ G+ I  ++ +DE W  G +  T R G+ P  YV+ I
Sbjct: 874  AKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVI 926



 Score = 37.7 bits (86), Expect = 0.39
 Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)

Query: 6616 RAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPANYVEAI 6669
            RA +D+ A    E+  + GD +   + ID+ W  G  +  GR G+ P  Y+E +
Sbjct: 799  RAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEG--EHHGRVGIFPRTYIELL 850


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
            [Homo sapiens]
          Length = 651

 Score = 53.1 bits (126), Expect = 9e-06
 Identities = 104/478 (21%), Positives = 197/478 (41%), Gaps = 50/478 (10%)

Query: 5653 KDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSD-TNYKKKFVKEKGKSNYSIMLEPPEV 5711
            KD  KK    GSY T PE++  V  K   ++ +D T  K     E+ K + S     PE 
Sbjct: 129  KDSKKKG---GSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPES 185

Query: 5712 KHAMEVAK--KQSDVAYRKDAKE-NLHYTTVADRP--DIKKATQAAKQASEVEYRAKHRK 5766
            +++  V+K   Q D    K++K+ N  +    + P  D+K++  +    SE+        
Sbjct: 186  QNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEI---CSENS 242

Query: 5767 EGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKG-KTPKYNPKDSQLYKVMKDANN 5825
                 L ++G+ D E     A L +   Y +N  K    K  KY  KD++  K  K +++
Sbjct: 243  LNVDFLMLVGQSDDESINFDAWLRN---YSQNNSKNYSLKYTKYTKKDTK--KNAKKSSD 297

Query: 5826 LASE--VKYKADLKKLHKPV--TDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTI 5881
              SE     K D KK+ K V   D K+ +  +     ++   S   +K  +K K      
Sbjct: 298  AESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKD 357

Query: 5882 PDNLEQLHLKEATELQS------------IVKYKEKYEKERGKPMLDFETPTYITAKESQ 5929
                +     E+T+ +S            + K  +  +K++    + F T +    +  +
Sbjct: 358  DKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKE 417

Query: 5930 QMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIA--SEKEYRKDLEESIRGKGL 5987
              +  K+ +KD +   K       E T A    K  +K     EK+ +KD ++  + K  
Sbjct: 418  SQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDA 477

Query: 5988 ------TEMEDTPDMLRAKNATQIL--NEKEYKRDLELEVKGRGLNAMANETPDF---MR 6036
                  TEME   ++ + K  ++    ++K+ K+D   + +        +    F    +
Sbjct: 478  KKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTK 537

Query: 6037 ARNATDIASQIKYKQSA--EMEKANFTSVVDTPEIIHAQQVKNLSSQK-KYKEDAEKS 6091
             + +   + +  YK  A  ++++++ TS     E + +++   +SS+K  + E  EK+
Sbjct: 538  IKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKA 595



 Score = 38.1 bits (87), Expect = 0.30
 Identities = 93/438 (21%), Positives = 162/438 (36%), Gaps = 44/438 (10%)

Query: 69  RKVIRKKVDPSKFMTPYIAHSQKMQDLFSPNKYKEKF--EKTKGQPYASTTDTPELRRIK 126
           +K   KK    K  TP    S+K    ++ N   ++   EKTK Q  A  T        +
Sbjct: 111 KKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENE 170

Query: 127 KVQDQLSEVKYRMDGDVAKTI---CHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKY 183
           + +   S  +   +   +KT+   C   +K KD +++KK +   ++ L+ +N    KD  
Sbjct: 171 QSKKSKSSSETNPESQNSKTVSKNCSQKDK-KDSKNSKKTN---TEFLHTKN-NPKKDLK 225

Query: 184 LLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQK---ALSDV 240
                   + +     ++    L       D+S+    N    LR  +Q      +L   
Sbjct: 226 RSKTSNDPISEICSENSLNVDFLMLVGQSDDESI----NFDAWLRNYSQNNSKNYSLKYT 281

Query: 241 AYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANA 300
            Y K   ++ A+ +  A+  D + AKK + +V K   K+D +  +K     T      + 
Sbjct: 282 KYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSK 341

Query: 301 RMNADNISTRKYQEDFENMKDQIYFMQ---TETPEYKMNKKAGVAASKVKYKEDYEKNKG 357
               D    +K  +  +  KD   + +   TE+ + K  +       K    +D +K+  
Sbjct: 342 DERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAK 401

Query: 358 KADYNVLPASE----NPQLRQLKAAGDALSD--KLYKENYEKTKAKSINYCETPKFKLD- 410
           K  ++    SE      Q  + K   D+ +D  K  K + E T A S    ++ K K D 
Sbjct: 402 KITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDE 461

Query: 411 --------------TVLQNFSSDKKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDK 456
                            +N  S +   D  LK    H   S E       +K  A+   +
Sbjct: 462 KKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH---SKEKKGSKKDIKKDARKDTE 518

Query: 457 NYKAEYEEDRGKGFFPQT 474
           +  AE++E    GF   T
Sbjct: 519 STDAEFDESSKTGFKTST 536



 Score = 34.7 bits (78), Expect = 3.3
 Identities = 78/412 (18%), Positives = 142/412 (34%), Gaps = 51/412 (12%)

Query: 5780 IEMAKKAAKLSSQVKYRENFDK--EKGKTPKYNPKDSQLYKVMKDANNLASEVK-----Y 5832
            I +++ + K  +Q  +   F K  ++G   K  P  SQ+     D   L    K      
Sbjct: 18   IPISESSRKSWNQKHFALTFPKPLQRGTNDKSRPLKSQITVTRHDKRKLEEGQKPAHKWI 77

Query: 5833 KADLKKLHK--PV-TDMKESLIMNHVLNTSQLASSYQYKKKYE------------KSKGH 5877
            +   +K+ +  P+ T  +E     H+  +       +YKK  +            K  G 
Sbjct: 78   RHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGGS 137

Query: 5878 YHTIPDNLEQLHLKEATELQSI-VKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKE 5936
            Y T P++ + +  K   + ++     K  +E E+ K           +++ + + Q+ K 
Sbjct: 138  YATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKS-------SSETNPESQNSKT 190

Query: 5937 YRKDYEESIKGRNLTGLEVTPALLHVKYATK---------------IASEKEYRKDLEES 5981
              K+  +  K  +    +     LH K   K               I SE     D    
Sbjct: 191  VSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLML 250

Query: 5982 IRGKGLTEMEDTPDMLRAKNATQILNEK-EYKRDLELEVKGRGLNAMANETPDFMRARNA 6040
            + G+   E  +    LR  +     N   +Y +  + + K     +   E+ D   A+  
Sbjct: 251  V-GQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKD 309

Query: 6041 TDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKY--KEDAEKSMSYYETV 6098
            +    +   K   + +    T   D        + K+    KK   K+D +K    Y   
Sbjct: 310  SKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPES 369

Query: 6099 LDTP--EIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKN 6148
             DT   + +  R + +N        D K    KIT   D+   L  KE+QK+
Sbjct: 370  TDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKD 421


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 242,161,294
Number of Sequences: 37866
Number of extensions: 10725178
Number of successful extensions: 35734
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 264
Number of HSP's that attempted gapping in prelim test: 22078
Number of HSP's gapped (non-prelim): 1892
length of query: 6669
length of database: 18,247,518
effective HSP length: 126
effective length of query: 6543
effective length of database: 13,476,402
effective search space: 88176098286
effective search space used: 88176098286
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 74 (33.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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