Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 115495445
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
(1341 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 2667 0.0
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 1346 0.0
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 499 e-141
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 383 e-106
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 380 e-105
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 370 e-102
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 349 9e-96
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 343 6e-94
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 330 7e-90
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 330 7e-90
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 330 7e-90
gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 312 1e-84
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 295 2e-79
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 295 2e-79
gi|239744894 PREDICTED: similar to Putative ankyrin repeat domai... 293 1e-78
gi|239757617 PREDICTED: similar to hCG1793014 [Homo sapiens] 287 5e-77
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 284 4e-76
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 283 6e-76
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 283 1e-75
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 281 3e-75
gi|239756223 PREDICTED: ankyrin repeat domain-containing protein... 277 6e-74
gi|239745040 PREDICTED: ankyrin repeat domain-containing protein... 277 6e-74
gi|169209369 PREDICTED: similar to Putative ankyrin repeat domai... 275 2e-73
gi|169194585 PREDICTED: similar to hCG1793014 [Homo sapiens] 256 1e-67
gi|169201955 PREDICTED: similar to hCG1793014 [Homo sapiens] 256 1e-67
gi|169192125 PREDICTED: similar to UNCoordinated family member (... 250 6e-66
gi|153791352 prostate, ovary, testis expressed protein on chromo... 219 1e-56
gi|239756067 PREDICTED: similar to Putative ankyrin repeat domai... 218 4e-56
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 215 2e-55
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 215 2e-55
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 2667 bits (6913), Expect = 0.0
Identities = 1341/1341 (100%), Positives = 1341/1341 (100%)
Query: 1 MTKRKKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQC 60
MTKRKKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQC
Sbjct: 1 MTKRKKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQC 60
Query: 61 HQEACANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPL 120
HQEACANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPL
Sbjct: 61 HQEACANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPL 120
Query: 121 LLSITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADI 180
LLSITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADI
Sbjct: 121 LLSITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADI 180
Query: 181 CGVTAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAE 240
CGVTAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAE
Sbjct: 181 CGVTAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAE 240
Query: 241 SLVEKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEE 300
SLVEKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEE
Sbjct: 241 SLVEKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEE 300
Query: 301 TPREITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRK 360
TPREITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRK
Sbjct: 301 TPREITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRK 360
Query: 361 IAWEKKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEE 420
IAWEKKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEE
Sbjct: 361 IAWEKKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEE 420
Query: 421 DEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQNSVPNK 480
DEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQNSVPNK
Sbjct: 421 DEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQNSVPNK 480
Query: 481 AFELKNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKING 540
AFELKNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKING
Sbjct: 481 AFELKNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKING 540
Query: 541 KLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKA 600
KLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKA
Sbjct: 541 KLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKA 600
Query: 601 LELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGK 660
LELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGK
Sbjct: 601 LELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGK 660
Query: 661 LEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKAL 720
LEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKAL
Sbjct: 661 LEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKAL 720
Query: 721 ELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKL 780
ELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKL
Sbjct: 721 ELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKL 780
Query: 781 EESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALE 840
EESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALE
Sbjct: 781 EESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALE 840
Query: 841 LKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDKISGKLE 900
LKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDKISGKLE
Sbjct: 841 LKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDKISGKLE 900
Query: 901 DSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQ 960
DSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQ
Sbjct: 901 DSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQ 960
Query: 961 KVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQ 1020
KVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQ
Sbjct: 961 KVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQ 1020
Query: 1021 DIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDI 1080
DIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDI
Sbjct: 1021 DIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDI 1080
Query: 1081 KILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKLKEKQDKEILEAEIE 1140
KILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKLKEKQDKEILEAEIE
Sbjct: 1081 KILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKLKEKQDKEILEAEIE 1140
Query: 1141 SHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDACLQRKMNVDVSSTIYNNEVLHQPLSEA 1200
SHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDACLQRKMNVDVSSTIYNNEVLHQPLSEA
Sbjct: 1141 SHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDACLQRKMNVDVSSTIYNNEVLHQPLSEA 1200
Query: 1201 QRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQ 1260
QRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQ
Sbjct: 1201 QRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQ 1260
Query: 1261 ESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHFLERKMQHHLLKEKNEEIFNY 1320
ESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHFLERKMQHHLLKEKNEEIFNY
Sbjct: 1261 ESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHFLERKMQHHLLKEKNEEIFNY 1320
Query: 1321 NNHLKNRIYQYEKEKAETENS 1341
NNHLKNRIYQYEKEKAETENS
Sbjct: 1321 NNHLKNRIYQYEKEKAETENS 1341
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 1346 bits (3483), Expect = 0.0
Identities = 799/1469 (54%), Positives = 930/1469 (63%), Gaps = 278/1469 (18%)
Query: 1 MTKRKKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQC 60
MT KK +NLN +D +KRTALHWACVNGH EVVTFLVDRKCQL+VLDGE RTPLMKALQC
Sbjct: 57 MTVGKKPVNLNKRDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQC 116
Query: 61 HQEACANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPL 120
+EACANILID+GAD+N VDVYGNTALHYAVYSE L +VA LLS+GAVIEV NKASLTPL
Sbjct: 117 EREACANILIDAGADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPL 176
Query: 121 LLSITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADI 180
LL+I KRS+Q VEFLL KNANANA N+ KCTALMLA+C GSSEIVGMLLQQNVDVFA DI
Sbjct: 177 LLAIQKRSKQTVEFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDI 236
Query: 181 CGVTAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAE 240
G+TAE YA CG ++IH+Q++E+IRKL KN QNTNPEGTS GTPDEAAPLAERTPDTAE
Sbjct: 237 HGITAERYAAACGVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAE 296
Query: 241 SLVEKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEE 300
SL+EKTPD EAA LVEGTS KIQCL KATSGKFEQS EE
Sbjct: 297 SLLEKTPD----------------------EAARLVEGTSAKIQCLGKATSGKFEQSTEE 334
Query: 301 TPREITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRK 360
TPR+I P KETSEKF+WPAK R RKI W
Sbjct: 335 TPRKILRPTKETSEKFSWPAKERSRKITW------------------------------- 363
Query: 361 IAWEKKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSE----- 415
E+KET VKT CVA VT NKT+VLEKG S MIACPTKE+STKAS N E
Sbjct: 364 ---EEKETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSL 420
Query: 416 -----------SKQEED-------------EEYSCDSRSLFESSAK-------------- 437
+K EED + Y+C + ++ K
Sbjct: 421 FGTRTIENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSE 480
Query: 438 ----------------------IQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQN 475
QVCIPES+YQKVMEINREVEE P+KPSAFKPA+EMQ
Sbjct: 481 SKREEDEEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQK 540
Query: 476 SVPNKAFELKNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEI 535
+VPNKAFELKNEQTLRA MFP ESKQKD EENSWDSES CETVSQKDV LPKATHQKE
Sbjct: 541 TVPNKAFELKNEQTLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEF 600
Query: 536 DKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKS 595
D ++GKLEESP KDGLLK TCG KVS+P KALELKD +TFKAE P K +P + S
Sbjct: 601 DTLSGKLEESPVKDGLLKPTCGRKVSLPNKALELKDRETFKAESPDKDGLLKPTCGRKVS 660
Query: 596 VPNKALELKNEQTLRAD----------------------------------EILPSESKQ 621
+PNKALELK+ +TL+A+ ++ PSESKQ
Sbjct: 661 LPNKALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQ 720
Query: 622 KDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSI 681
KD EENSWD ES ET+ Q DVCLPKA HQKE D ++GKLE SP KDGLLK CGMK+S+
Sbjct: 721 KDDEENSWDFESFLETLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISL 780
Query: 682 PTKALELMDMQTFKAEPPEK-PSAF----EPAIEMQKSV-------------PNKALELK 723
P KALEL D +TFKAE S F +P E +S K + +
Sbjct: 781 PNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTKEGATKTVTGQ 840
Query: 724 NEQTLRADEILP---------SESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEID 774
E+ + E P SE +K+ +S+ DSE + + +Q CLP+AT+QKEI
Sbjct: 841 QERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEIK 900
Query: 775 KINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSV 834
NGK+EESP+ + M+ S+P K LE
Sbjct: 901 TTNGKIEESPEKPSHFEPATEMQNSVPNKGLE---------------------------- 932
Query: 835 PNKALELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDK 894
KN+QTLRAD + K+ + E RE +KD C ++
Sbjct: 933 ------WKNKQTLRAD-----STTLSKILDALPSCERGREL--KKDNC----------EQ 969
Query: 895 ISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIK 954
I+ K+E + + +L A+E+ K E + K EQ + C ++ L++ +E +
Sbjct: 970 ITAKMEQTKNKFCVLQ--KELSEAKEI-KSQLENQKAKWEQ---ELCSVRLTLNQEEEKR 1023
Query: 955 SQLE--NQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQ 1012
++ +K++ E++L Q E+ R DI + + L ++ H E ++
Sbjct: 1024 RNVDILKEKIRPEEQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDL--- 1080
Query: 1013 LEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEK 1072
HEN L E MLK E +ATLKHQ+Q K
Sbjct: 1081 ------------------------FHEN-CMLKKEIAMLKLE-------VATLKHQHQVK 1108
Query: 1073 ENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKLKEKQDK 1132
ENKYFEDIKIL+EKNAELQMTLKLK++++TKRASQY QLKVL AENTMLTSKLKEKQDK
Sbjct: 1109 ENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKLKEKQDK 1168
Query: 1133 EILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDACLQRKMNVDVSSTIYNNEV 1192
EILE EIESHHPRLASA+QDHDQ VTSRK+QE AFH AGDA LQ MNVDVS+TIYNNEV
Sbjct: 1169 EILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGDAPLQGIMNVDVSNTIYNNEV 1228
Query: 1193 LHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDN 1252
LHQPL EAQRKSKS KINLNYAGD LREN LVSEHAQRD+ ETQCQMK+AEHMYQNEQDN
Sbjct: 1229 LHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQRDRCETQCQMKKAEHMYQNEQDN 1288
Query: 1253 VNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHFLERKMQHHLLKE 1312
V+KHTEQQESL+QKLFQL+SKN WL+QQLV+AHKK NKSK+TI+I F E KMQ H L E
Sbjct: 1289 VDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKV-NKSKVTINIQFPEMKMQRH-LNE 1346
Query: 1313 KNEEIFNYNNHLKNRIYQYEKEKAETENS 1341
KNEE+FNY NHLK RI QYEKEKAE E S
Sbjct: 1347 KNEEVFNYGNHLKERIDQYEKEKAEREVS 1375
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 499 bits (1284), Expect = e-141
Identities = 384/1078 (35%), Positives = 556/1078 (51%), Gaps = 134/1078 (12%)
Query: 364 EKKETPVKTGCVARVTSNKTKVLE---KGRSKMIACPTKESSTK--ASANDQRFPSESKQ 418
E K T + V+ K +++E K ++ + A ESS + + ++R P S Q
Sbjct: 173 EAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVDKLESSHQLISEYKEERIPKHSSQ 232
Query: 419 EED--EEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQNS 476
+ +E S DS S + P S + ++N + + PK PS K Q S
Sbjct: 233 NSNSVDESSEDSLSRLSGKPGVDDSWPTSDDE---DLNFDTKNVPK-PSLAKLMTASQQS 288
Query: 477 VPNKAFELKNEQTLRADPMFPPESKQKD------YEENSWDSESLCETVSQKDVCLPKAT 530
N +T +S +D S + Q LPK +
Sbjct: 289 RKNLEATYGTVRTGNRTLFEDRDSDSQDEVVVESLPTTSIKVQCFSHPTYQSPDLLPKPS 348
Query: 531 HQKEIDKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPAT 590
H+ + G ++E P K G+ K G+ + E A
Sbjct: 349 HKSLANP--GLMKEEPTKPGIAKKENGIDI-------------------------IESAP 381
Query: 591 EMQKSVPNKALELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVC-LPKAA 649
Q + N + + R+D + Q++ E+ WD+ES+ E QK V L AA
Sbjct: 382 LEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWDSESISENFPQKYVDPLAGAA 441
Query: 650 HQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI 709
KE + N + E + + K++ + + M E PE+ +P I
Sbjct: 442 DGKEKNIGNEQAEDVFYIPSCMSGSRNFKMA-KLEDTRNVGMPVAHMESPERYLHLKPTI 500
Query: 710 EMQKSVPNKALELKNEQTLRADEI-LPSESKQKDYEESSWDSESLCETVSQKDVCLPKAT 768
EM+ SVPNKA +K+ QT +A E L S+++ E S +++ E +K
Sbjct: 501 EMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSENNQPQVEEERKKHRNNEMEV 560
Query: 769 HQKEIDKINGKLEESPDNDGFL---KAPCRMKVSIPTK----------ALELMDMQ-TFK 814
D E+ D+DG + K+ P K AL++ +++ T K
Sbjct: 561 SANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKENKEYASSGPALQMKEVKSTEK 620
Query: 815 AEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRA---DQMFPSE------SKQKKVEEN 865
+ K S P + L++ ++ +L D+ P++ +K K ++
Sbjct: 621 EKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDEGRPTKKTSNEKNKVKNQIQS 680
Query: 866 SWDSESLRET--VSQKDVCVPKATHQKEM---DKISGKLEDSTSLSKILDTVHSCERARE 920
D + L ++ + +D +P ++++ M +++ + +DS SL KI D SCER E
Sbjct: 681 MDDVDDLTQSSETASEDCELPHSSYKNFMLLIEQLGMECKDSVSLLKIQDAALSCERLLE 740
Query: 921 LQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEE 980
L+K+HCE T K+++M+ K VL+++LSE KEIKSQLE+QKV+WE+ELCS+R +LNQEEE
Sbjct: 741 LKKNHCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEE 800
Query: 981 KRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQV------ 1034
KRRNAD L EKIRE+L R EEQ+RKE+EVKQQLE +L+ ++EL++V+SNLNQV
Sbjct: 801 KRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERND 860
Query: 1035 ----------------------------------------SHTHENENYLLHENCMLKKE 1054
SH+HE E L H+N ML++E
Sbjct: 861 AQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEE 920
Query: 1055 IAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKV 1114
IAML+LEI T+K+Q QEKE K FED+KI+KEKN +LQ T+K EE+LT+ SQY+G+L V
Sbjct: 921 IAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSV 980
Query: 1115 LIAENTMLTSKLK-EKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDA 1173
L AEN ML SKL+ EKQ KE LEAE+ES+H RLA+A+ D DQ TS++ E AF A D
Sbjct: 981 LTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDE 1040
Query: 1174 C--LQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRD 1231
C LQ KMN DVS+ NNE+L Q L + + K SL+I ++ DALRE TL E Q+D
Sbjct: 1041 CSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKD 1100
Query: 1232 QRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNK 1291
+TQCQMKE E YQNEQ VNK+ +QES++++L QLQS+NM L+QQL AH KADNK
Sbjct: 1101 LSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNK 1160
Query: 1292 SKITIDI----HFLERKMQHH------LLKEKNEEIFNYNNHLKNRIYQYEKEKAETE 1339
K I+I H + +K+Q LL+E+N+E+ + NHLK R YQYE EKAE E
Sbjct: 1161 EKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAERE 1218
Score = 211 bits (537), Expect = 4e-54
Identities = 311/1437 (21%), Positives = 575/1437 (40%), Gaps = 236/1437 (16%)
Query: 10 LNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANIL 69
LN +D RTALH AC NGH EVVT LVDRKCQL+V D E+RT LMKA+QC +E CA IL
Sbjct: 73 LNDRDKMNRTALHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATIL 132
Query: 70 IDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSE 129
++ GAD NL DV+GNTALHYAVY+E +SV KLL +
Sbjct: 133 LEHGADPNLADVHGNTALHYAVYNEDISVATKLLLY------------------------ 168
Query: 130 QIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYA 189
+AN A NK T L+LAV ++V L+++ +V A D
Sbjct: 169 ---------DANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKANVNAVD---------- 209
Query: 190 VTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPDE 249
H+ I EY + H + N + D + L+ + P +S ++
Sbjct: 210 ---KLESSHQLISEYKEERIPKHSSQNSNSVDESSEDSLSRLSGK-PGVDDSWPTSDDED 265
Query: 250 AAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPREITSPA 309
+ P + + + ++ +E T ++ + FE ++ E+ +
Sbjct: 266 LNFDTKNVPKPSLAKLMTASQQSRKNLEATYGTVRTGNRTL---FEDRDSDSQDEVVVES 322
Query: 310 KETS----EKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEK 365
T+ + F+ P P +++ S K P K K
Sbjct: 323 LPTTSIKVQCFSHPTYQSP-------------DLLPKPSHKSLANPGLMKEEPTKPGIAK 369
Query: 366 KETPVK--TGCVARVTSNKT-----KVLEKGRSKMIAC------PTKESSTKASANDQRF 412
KE + T+N +V + RS M++ ES + + + F
Sbjct: 370 KENGIDIIESAPLEQTNNDNLTYVDEVHKNNRSDMMSALGLGQEEDIESPWDSESISENF 429
Query: 413 PSE-----------------SKQEEDEEY--SCDSRSLFESSAKIQVCIPESIYQKVMEI 453
P + ++Q ED Y SC S S AK++ ++ V +
Sbjct: 430 PQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKMAKLE--DTRNVGMPVAHM 487
Query: 454 NREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLR-ADPMFPPESKQKDYEENSWDS 512
E P++ KP IEM++SVPNKA +K+ QT + A+ S+++ E S ++
Sbjct: 488 -----ESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSENN 542
Query: 513 ESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKATCGMKV---SIPTK---- 565
+ E +K D E+ + DGL++ + P K
Sbjct: 543 QPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGETDHQQFPRKENKE 602
Query: 566 ------ALELKDMQ-TFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTLR---ADEIL 615
AL++K+++ T K + K S P + L++ ++ +L DE
Sbjct: 603 YASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDDSSLSEIDEDEGR 662
Query: 616 PS------ESKQKDYEENSWDTESLCET--VSQKDVCLPKAAHQKEIDKINGKLEGSPVK 667
P+ ++K K+ ++ D + L ++ + +D LP ++++ +
Sbjct: 663 PTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFM------------- 709
Query: 668 DGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQK------SVPNKALE 721
LL GM+ L++ D + E +E++K +V K +E
Sbjct: 710 --LLIEQLGMECKDSVSLLKIQDAAL----------SCERLLELKKNHCELLTVKIKKME 757
Query: 722 LKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLE 781
K R Q ++++ W+ E LC L + +Q+E + N
Sbjct: 758 DKVNVLQRELSETKEIKSQLEHQKVEWERE-LCS--------LRFSLNQEEEKRRNADTL 808
Query: 782 ESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALEL 841
+ + + + + K + +QT + E S ++ + +
Sbjct: 809 YEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSRE 868
Query: 842 KNEQTLRADQMFPSESKQKKVE--ENSWDSESLRETVSQKDVCVPKATHQKEMDKISGKL 899
+N + L+ + SKQK++E + +SE+ +KD+ + Q+E+ + +L
Sbjct: 869 QNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAML--RL 926
Query: 900 EDSTSLSKILDTVHSC--------ERARELQK----------DHCEQRTGKMEQMKKKFC 941
E T ++ + C E+ +LQK Q G++ + +
Sbjct: 927 EIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENA 986
Query: 942 VLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEE 1001
+L KL K+ K +LE + + L + +Q E +R ++ ++ R+E R+++
Sbjct: 987 MLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQD 1046
Query: 1002 QHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCM----LKKEIAM 1057
+ ++ L+ I +L ES LN + + L E + ++K+++
Sbjct: 1047 KMNFDV---SNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQ 1103
Query: 1058 LKLEIATLKHQYQE---KENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKV 1114
+ ++ ++ +YQ K NKY + ++E+ ++LQ L + L ++ + K
Sbjct: 1104 TQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKT 1163
Query: 1115 LI---AENTMLTSKLKEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAG 1171
+I + + KL+ + +K+ L +E + L S + ++++ A
Sbjct: 1164 VINIQDQFHAIVQKLQAESEKQSL--LLEERNKELISECNHLKERQYQYENEK-----AE 1216
Query: 1172 DACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKS-LKINLNYAGDALRE-----NTLVS 1225
+ R++ +++ T+ Q +SEA + S +INL L++ +
Sbjct: 1217 REVVVRQLQQELADTLKK-----QSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQ 1271
Query: 1226 EHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAH 1285
E R +C K +H + E+DN ++ +D K LQ+ L++A+
Sbjct: 1272 EAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMD--------KIEELQKNLLNAN 1323
Query: 1286 KKADNKSKITIDIHFLERKMQHHLLKE--KNEEIFNYNNHLKNRIYQYEKEKAETEN 1340
D K ++ + L++ ++ +L +E KN E+ KN + K+ E EN
Sbjct: 1324 LSEDEKEQLK-KLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYEN 1379
Score = 52.0 bits (123), Expect = 4e-06
Identities = 137/663 (20%), Positives = 259/663 (39%), Gaps = 88/663 (13%)
Query: 499 ESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKATCGM 558
E QK ++N E+L +T+SQ + L T + + +N KLE L+A
Sbjct: 954 EDLQKTIKQNE---ETLTQTISQYNGRLSVLTAENAM--LNSKLENEKQSKERLEAEVES 1008
Query: 559 KVSIPTKALELKDM-QTFKAEPP-GKPSAFEPATEMQKSVPNKALELKNEQTLRADEILP 616
S A+ +D +T K E A + + +Q + LK+ + + ++
Sbjct: 1009 YHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFK 1068
Query: 617 SESKQKDYE-----------ENSWDTESLCETVSQKDVCLPKAAHQK------EIDKING 659
+ESK E E + E + + +SQ C K QK +++K G
Sbjct: 1069 TESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQ-CQMKEMEQKYQNEQVKVNKYIG 1127
Query: 660 KLEG----------------SPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPS 703
K E + D KA+ K I + +Q +AE ++
Sbjct: 1128 KQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSL 1187
Query: 704 AFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWD-------SESLCET 756
E E K + ++ LK Q +E E + ++ D SE+ E
Sbjct: 1188 LLE---ERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEV 1244
Query: 757 VSQKDVCLPKATH--QKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFK 814
S+ + L T +K++ +I +L+E+ D C K+ + LE D K
Sbjct: 1245 TSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEA-VRCAEKMQDHKQKLE-KDNAKLK 1302
Query: 815 AEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSESLRE 874
++ E E+QK++ N L ++ L+ + +E + E RE
Sbjct: 1303 VTVKKQMDKIE---ELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELERE 1359
Query: 875 TVSQKDVC--VPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGK 932
K++ K ++ E + S + TS ++ ++ + + E K
Sbjct: 1360 ITGFKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSK 1419
Query: 933 MEQMKKKFCVLKKKLSEAKEIKSQ---LENQKVKWEQELCSVRLTLNQEEEKRRNADILN 989
+ K +L+++L K ++ + L+ K K EQE+ ++R +
Sbjct: 1420 CLHLDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHI-------------- 1465
Query: 990 EKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENC 1049
E+ ELG+++ Q+++E+E + + E A +++++ L +Q + EN
Sbjct: 1466 ERNMVELGQVK-QYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKS 1524
Query: 1050 MLKKEIAMLKLEIATLKHQYQEKENK---------YFEDIKILKEKNAELQMTLKLKEES 1100
++ I L+ E++ +K QE NK Y E++K+ K +++L T + E
Sbjct: 1525 QMELRIKDLESELSKIKTS-QEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEV 1583
Query: 1101 LTK 1103
TK
Sbjct: 1584 NTK 1586
Score = 50.1 bits (118), Expect = 1e-05
Identities = 137/797 (17%), Positives = 317/797 (39%), Gaps = 87/797 (10%)
Query: 418 QEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVE--------EPPKKPSAFKP 469
QEE++ + D+ L+E + Q+ E Y+K +E+ +++E E S
Sbjct: 797 QEEEKRRNADT--LYEKIRE-QLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQ 853
Query: 470 AIEMQNSVPNKAFELKNEQTLRADPMFPPESKQKDYE--ENSWDSESLCETVSQKDVCLP 527
++ +N + +N + L+ + SKQK+ E + +SE+ +KD+
Sbjct: 854 VVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSENSHSHEEEKDLSHK 913
Query: 528 KATHQKEIDKINGKLEESPNKDGLLKATCGMKVSIPTKALE-----LKDMQTFKAEPPGK 582
+ Q+EI + +++ N++ + C + I + E +K + + +
Sbjct: 914 NSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQ 973
Query: 583 PSAFEPATEMQKSVPNKALELKNEQTLRADEILPS---------------ESKQKDYEEN 627
+ + ++ N LE + + R + + S E+ +++ E
Sbjct: 974 YNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELA 1033
Query: 628 SWDTESLCETVSQK---DVCLPKAAHQ-------KEIDKING-KLEGSPVKDGLLKANCG 676
C + K DV K ++ K K+N ++E +D L + G
Sbjct: 1034 FQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLG 1093
Query: 677 MKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPS 736
++ + M+ + + + I Q+SV + +L++E L ++ +
Sbjct: 1094 LERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDA 1153
Query: 737 ESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKA-PCR 795
+K + E++ + + + QK +A +K+ + + +E LK +
Sbjct: 1154 HNKADNKEKTVINIQDQFHAIVQK----LQAESEKQSLLLEERNKELISECNHLKERQYQ 1209
Query: 796 MKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQK----SVPNKALELKNEQTLRADQ 851
+ + + + +Q A+ +K S E ++E+ ++ ++ +LK + +Q
Sbjct: 1210 YENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQ 1269
Query: 852 MFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDT 911
+ ++ + + + + ++ + +KD K T +K+MDKI ++ + + D
Sbjct: 1270 LQEAQDRHTEAVRCAEKMQDHKQKL-EKDNAKLKVTVKKQMDKIEELQKNLLNANLSEDE 1328
Query: 912 VHSCERARELQKD---HCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQEL 968
++ EL++ + +Q K +++++ K L ++ ++ EN + + +L
Sbjct: 1329 KEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDL 1388
Query: 969 CSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRK--ELEVKQQLEQALRIQDIELKS 1026
+ + ++ + K L KI + +E K L+ K Q+ Q EL S
Sbjct: 1389 KTSQFEMDIQINK------LKHKIDDLTAELETAGSKCLHLDTKNQILQE------ELLS 1436
Query: 1027 VESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEK 1086
+++ + +N+ L E L+ I +E+ +K QE E +
Sbjct: 1437 MKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEER----------- 1485
Query: 1087 NAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKLKEKQDKEILEAEIESHHPRL 1146
A ++ KLKE +L +A S + EN + K E+ ++ES ++
Sbjct: 1486 -ARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASM----KSQMELRIKDLESELSKI 1540
Query: 1147 ASAVQDHDQIVTSRKSQ 1163
++ +D ++ + Q
Sbjct: 1541 KTSQEDFNKTELEKYKQ 1557
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 383 bits (983), Expect = e-106
Identities = 359/1226 (29%), Positives = 568/1226 (46%), Gaps = 134/1226 (10%)
Query: 184 TAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLV 243
+AE CG + + + K + G A E PL T ++ +
Sbjct: 156 SAEKLDAACGIDKTENGTLFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDSDHIS 215
Query: 244 EKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPR 303
+ L ++E E+ P +L E + + S P
Sbjct: 216 TRFLGSMDSLT-----SSEESSERPPLSTLTLKEADPSSKAAMRRKDS---------PPP 261
Query: 304 EITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAW 363
S K+ +EK T K IA E KE +S K+ +EK T K IA
Sbjct: 262 GKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIAT 321
Query: 364 EKKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEE 423
E KE ++G V+ + KV+ K + ++ T+ + S + S Q++
Sbjct: 322 EIKEGQ-QSGTVSPQKQSAWKVIFKKKVSLLNIATRITGGGKSG------TVSSQKQPPS 374
Query: 424 YSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQNSVPNKAFE 483
+ ++ +S+ I I + + + +K A K + ++SV N A E
Sbjct: 375 KATSDKT--DSALNIATEIKDGLQCGTVS--------SQKQPALKATTDEEDSVSNIATE 424
Query: 484 LKN-EQTLRADPMFPPESKQKDYEENSW--------DSESLCETVSQKDVCLPKATHQKE 534
+K+ E++ P K EE+S D E SQK L T +++
Sbjct: 425 IKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEED 484
Query: 535 -IDKINGKLEE-------SPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAF 586
+ I ++++ S K LKAT K S E KD + + KP A
Sbjct: 485 SVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPAL 544
Query: 587 EPATEMQKSVPNKALELKNEQTLRA---------------DEILPSESKQKDYEENSWDT 631
+ ++ + SV + A E K+ + R + L + ++ K Y E +
Sbjct: 545 KATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRV 604
Query: 632 ES----LCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALE 687
S + S K+ +P A + + ++I+G + S K LKA K S+ E
Sbjct: 605 SSHKQPALKATSDKENSVPNMATETKDEQISGTV--SSQKQPALKATSDKKDSVSNIPTE 662
Query: 688 LMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESS 747
+ D Q +K A++ + SV N A E+K+ Q I + S Q+
Sbjct: 663 IKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATEIKDGQ------IRGTVSSQRQ----- 711
Query: 748 WDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALEL 807
+L T +KD A K+ +K +G + SP K + KVS+ A +
Sbjct: 712 ---PALKATGDEKDSVSNIAREIKDGEK-SGTV--SPQKQSAQKVIFKKKVSLLNIATRI 765
Query: 808 MDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQT---LRADQMFPSESKQKKVEE 864
E PE + IE + SV N A ++K+ QT D SE +QK++EE
Sbjct: 766 TGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEE 825
Query: 865 NSWDSESLRETVSQKD------------------VCVPKATHQKEMDKISGKLEDSTSLS 906
+ ++ + +D +C +D+ K +D L
Sbjct: 826 YENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLL 885
Query: 907 KILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQ 966
KI T C+R EL+ +HCEQ K+ ++K K VL+K+LSE +EIKSQL+++ ++ E+
Sbjct: 886 KIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEK 945
Query: 967 ELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKS 1026
ELCS+R + QE++KRRN + L++K+RE+L EEQ+R E +V + ++ AL+ ++ELK+
Sbjct: 946 ELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKT 1005
Query: 1027 VESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEK 1086
+N NQVS T E E+ LLHEN +++ EIA L+LE T+K+Q EK KY +D +I+K K
Sbjct: 1006 GGNNSNQVSETDEKED-LLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRK 1062
Query: 1087 NAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAEIESHHPR 1145
+ +LQ LK EE+L + + YSGQL L ENT L SKL K+++ + LE E++S+ R
Sbjct: 1063 HEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCR 1122
Query: 1146 LASAVQDHDQIVTSRKSQEPAFHIAGDAC--LQRKMNVDVSSTIYNNEVLHQPLSEAQRK 1203
L +A+ DHDQ +S++ QE AF D C LQ +N V +L LS+A+ K
Sbjct: 1123 LNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVL-------ILSLQLSKAESK 1175
Query: 1204 SKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESL 1263
+ L+ L+Y G+AL+E LV EH Q + ++ Q QMK+ E MY++ + + K E+QE
Sbjct: 1176 FRVLETELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE-- 1233
Query: 1264 DQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF--------LERKMQHH--LLKEK 1313
+ QL+ +NM LQQQL A KADN+ K ++I L+ + + H LL+E
Sbjct: 1234 --RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEED 1291
Query: 1314 NEEIFNYNNHLKNRIYQYEKEKAETE 1339
N+ + N NH K + QYEKEKAE E
Sbjct: 1292 NKMLVNELNHSKEKKCQYEKEKAERE 1317
Score = 76.3 bits (186), Expect = 2e-13
Identities = 218/1134 (19%), Positives = 427/1134 (37%), Gaps = 158/1134 (13%)
Query: 255 ERTPDTAESLVEKTPDEAASLVEGTSDKIQC----LEKATSGKFEQSAEETPREITSPAK 310
++ P A S +KT D A ++ D +QC +K + K E++ I + K
Sbjct: 370 KQPPSKATS--DKT-DSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIK 426
Query: 311 ETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKETPV 370
+ + T ++ +P A +ED+ I + K+ + T +++ +P A +E V
Sbjct: 427 DGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTDEEDSV 486
Query: 371 KTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRS 430
T++ + +S ++ K + S F + +++++D E S S
Sbjct: 487 SIIA--------TEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSS 538
Query: 431 LFESSAKIQVCIPESIYQKVMEINREVEEPPK-------KPSAFKPAIEMQNSVPNKAFE 483
+ K +S V+ I RE ++ K +P K + ++S+ N A
Sbjct: 539 QKPPALKATSDEEDS----VLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARG 594
Query: 484 LK-NEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKL 542
K E+T R P K +ENS +P + + ++I+G +
Sbjct: 595 KKYGEKTRRVSSHKQPALKATSDKENS----------------VPNMATETKDEQISGTV 638
Query: 543 EESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALE 602
S K LKAT K S+ E+KD Q K A++ + + SV N A E
Sbjct: 639 --SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQLAWKATSVKKDSVSNIATE 696
Query: 603 LKNEQ-----TLRADEILPSESKQKDYEENSW----DTESLCETVSQKDVCLPKAAHQKE 653
+K+ Q + + L + +KD N D E TVS + K +K+
Sbjct: 697 IKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEK-SGTVSPQKQSAQKVIFKKK 755
Query: 654 IDKIN-------GKLEGSPVKDGL--LKANCGMKVSIPTKALELMDMQTFKAEPPEKPSA 704
+ +N G G+ + L LKA K S+ A ++ D+QT + A
Sbjct: 756 VSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMA 815
Query: 705 FEPAIEMQKSVPNKALELKNEQTLRADE---ILPSESKQKDYEESSWDSESLCETVSQKD 761
E + + N ++KN+ R D I S++ +D + + +++ + Q +
Sbjct: 816 SEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHE 875
Query: 762 VCLPKATHQKEIDK---INGKLEESPDND-GFLKAPCRM---KVSIPTKALELMDMQTFK 814
+ H +I K + +L E DN L+ R K S+ K L + + K
Sbjct: 876 MKCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLS--EKEEIK 933
Query: 815 AEPPEKPSAFEPAI------------------EMQKSVPNKALELKNEQTLRADQMFPSE 856
++ + E + E+ + V K + + + AD P +
Sbjct: 934 SQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIK 993
Query: 857 SKQKKVE----ENSWDSESLRETVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKIL--- 909
K E +S + ET ++D+ Q E+ ++ +LE T ++ L
Sbjct: 994 PALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARL--RLEKDTIKNQNLEKK 1051
Query: 910 -------------DTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQ 956
D + +R E + +G++ + + L+ KL + +E +
Sbjct: 1052 YLKDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQR 1111
Query: 957 LENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQA 1016
LE + + L + +Q +R+ ++ + G ++ K +++ L
Sbjct: 1112 LETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQ------GTVD----KCCHLQENLNSH 1161
Query: 1017 LRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKY 1076
+ I ++L ES + L E ++ + + + E+ + Q ++ E Y
Sbjct: 1162 VLILSLQLSKAESKFRVLETELHYTGEALKEKALVFEHV---QSELKQKQSQMKDIEKMY 1218
Query: 1077 FEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKLKEKQDKEILE 1136
+++ + + +LK++++ + + K E +L + + E L+
Sbjct: 1219 KSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQ 1278
Query: 1137 AEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDACLQRKMNVDVSSTIYNNEVLHQP 1196
AE H L +D+ +V H C K + + L Q
Sbjct: 1279 AECRKHRLLLE---EDNKMLVNELN------HSKEKKCQYEKEKAEREVAVRQ---LQQK 1326
Query: 1197 LSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKH 1256
+ K + K L DA + + E+ +D R+ QM+ Q++ +
Sbjct: 1327 QDDVLNKRSATKALL----DASSRHCIYLENGMQDSRKKLDQMRSQFQEIQDQLTATIRC 1382
Query: 1257 TEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHFLERKMQHHLL 1310
T++ E QK L+ +N+ +++ + KK D + I E+ +QH L
Sbjct: 1383 TKEMEGDAQK---LEVENVMMRKII----KKQDEQ------IERFEKILQHSSL 1423
Score = 54.3 bits (129), Expect = 8e-07
Identities = 177/930 (19%), Positives = 350/930 (37%), Gaps = 118/930 (12%)
Query: 207 KLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPDEAAPLVERTPDTAESLVE 266
++S+ + P A + +E + L+ + E P ++ T D +SL+
Sbjct: 531 EISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLN 590
Query: 267 KTPDEA-ASLVEGTSDKIQCLEKATSGKFEQSAEETPREITSPAKETSEKFTWPAKGRPR 325
+ S Q KATS K E + + + K+ T ++ +P
Sbjct: 591 IARGKKYGEKTRRVSSHKQPALKATSDK-----ENSVPNMATETKDEQISGTVSSQKQPA 645
Query: 326 KIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKETPVKTGCVARVTSNKTKV 385
A K+D+ I + K+ + T +++ +++AW K T VK V+ + +
Sbjct: 646 LKATSDKKDSVSNIPTEIKDGQQSGTVSSQ---KQLAW--KATSVKKDSVSNIATE---- 696
Query: 386 LEKGRSKMIACPTKESSTKASANDQRFPSESKQE-EDEEYSCDSRSLFESSAKIQVCIPE 444
++ G+ + ++ + KA+ +++ S +E +D E S +S+ K+
Sbjct: 697 IKDGQIRGTVSSQRQPALKATGDEKDSVSNIAREIKDGEKSGTVSPQKQSAQKVIFKKKV 756
Query: 445 SIYQKVMEIN---REVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQT---LRADPMFPP 498
S+ I + E P+ K IE +NSV N A ++K+ QT D
Sbjct: 757 SLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMAS 816
Query: 499 ESKQK---DYEENSWDSESLCETVSQKDVCLPKATHQKE---------------IDKING 540
E +QK +YE N ++ + D + + E ID+
Sbjct: 817 EGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEM 876
Query: 541 KLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPAT----EMQKSV 596
K ++ + + K C K K + ++ + K S + E++ +
Sbjct: 877 KCKDCVHLLKIKKTFCLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQL 936
Query: 597 PNKALELKNEQTLRADEILPSESKQKDYEE-NSWDTESLCETVSQ----KDVCLP--KAA 649
++ LEL+ E I + K+++ EE + E L T Q DV P A
Sbjct: 937 KHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPAL 996
Query: 650 HQKEIDKINGKLEGSPV-----KDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSA 704
E++ G + V K+ LL N M+ I LE T K + EK
Sbjct: 997 KSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLE---KDTIKNQNLEKKYL 1053
Query: 705 FEPAIEMQKSVPNKALELKNEQTLR-------------ADEILPSESKQKDYEESSWDSE 751
+ I +K + +NE+TL DE SK + ES
Sbjct: 1054 KDFEIVKRKHEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESG---- 1109
Query: 752 SLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQ 811
ET Q C A + K ++ G + C ++ ++ + L ++ +Q
Sbjct: 1110 QRLETEMQSYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVL-ILSLQ 1168
Query: 812 TFKAEPPEKPSAFEPAIEMQ-KSVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSE 870
KAE K E + +++ KAL ++ Q+ ++ +S+ K +E+
Sbjct: 1169 LSKAE--SKFRVLETELHYTGEALKEKALVFEHVQS----ELKQKQSQMKDIEKMYKSGY 1222
Query: 871 SLRETVSQKD--VCVPKATH---QKEMDKISGKLEDSTSL---------SKILDTVHSCE 916
+ E +K C K + Q+++D K ++ +++ + C
Sbjct: 1223 NTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVENLQAECR 1282
Query: 917 RARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTL- 975
+ R L ++ + ++ K+K C +K+ +E + QL+ ++ + + + L
Sbjct: 1283 KHRLLLEEDNKMLVNELNHSKEKKCQYEKEKAEREVAVRQLQQKQDDVLNKRSATKALLD 1342
Query: 976 ----------NQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLE---QALRIQDI 1022
N ++ R+ D ++R + I++Q + +++E Q L ++++
Sbjct: 1343 ASSRHCIYLENGMQDSRKKLD----QMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENV 1398
Query: 1023 ELKSVESNLNQVSHTHENENYLLHENCMLK 1052
++ + Q E L H + ML+
Sbjct: 1399 MMRKIIK--KQDEQIERFEKILQHSSLMLQ 1426
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 380 bits (975), Expect = e-105
Identities = 382/1290 (29%), Positives = 581/1290 (45%), Gaps = 168/1290 (13%)
Query: 184 TAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLV 243
+AE+ CG M + + K + G A E PL T + +
Sbjct: 156 SAENLDAACGIDKTENGNMFEDQNVDKEGKALPATGQKANVSPEQPPLFTHTVKDRDHIS 215
Query: 244 EK--------TPDEAAPLVERTPDTAESLVEKTPDEAASLVEG-------TSDKIQCLEK 288
+ T E + ER P + +L E P A++ S + Q EK
Sbjct: 216 TRFLGGMDSLTSSEESS--ERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEK 273
Query: 289 ATSGKFEQSAEETPREI--------TSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIM 340
ATS + S EI S K+ +EK T K IA E K+ +
Sbjct: 274 ATSDD-KDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKKGQQSGTV 332
Query: 341 SPAKETSEKFTWAAKGRPRKIAWEKKETPVKTGCVARVTSNKTKVLEKGRSKM------I 394
SP K+++ K + K IA T + G + S++ + K S I
Sbjct: 333 SPQKQSAWKVIFKKKVSLLNIA-----TRIMGGGKSGTVSSQKQPASKATSDKTDSALNI 387
Query: 395 ACPTKESSTKASANDQRFPSESKQEEDEEYSC--------DSRSLFESSAKIQVCIPESI 446
A K+ + + Q+ P+ K DEE S D S++ Q + +
Sbjct: 388 ATEIKDGLQCGTVSSQKQPA-LKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALKATT 446
Query: 447 YQK--VMEINREVEEPPK-------KPSAFKPAIEMQNSV-----PNKAFELKNEQTLRA 492
+K V I E+++ K KP A + + SV NK E + R
Sbjct: 447 DEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRK 506
Query: 493 DPMFPPESKQKDYEEN----SWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNK 548
P S +KD N D E + SQK L K T +E D + G E NK
Sbjct: 507 KPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTL-KGTSDEE-DSVLGIARE--NK 562
Query: 549 DGL------------LKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSV 596
DG LKA+ K S+ A KD + K K + E ++ + S
Sbjct: 563 DGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSF 622
Query: 597 PNKALELKNEQTLRA----------------DEILPSESKQKDYEEN----SWDTESLCE 636
N E K+ + R D +L + KD E++ S L
Sbjct: 623 SNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKA 682
Query: 637 TVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKA 696
T +KD L A +K+ +K + SP K LKA C + S+P A E D Q
Sbjct: 683 TSDEKDSVLNIARGKKDGEKT--RTVSSP-KQPALKAICDKEDSVPNMATEKKDEQISGT 739
Query: 697 EPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCET 756
+K A + + + SV N E+K+ Q S KQ ++ +S +S+
Sbjct: 740 VSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGT----VSSQKQPAWKATSVKKDSVSNI 795
Query: 757 VSQ------KDVCLPKATHQKEIDKINGKLEE-------SPDNDGFLKAPCRMKVSIPTK 803
++ + + + T D+I K SP K + KVS+
Sbjct: 796 ATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLNKSAGVSPQKQSAQKVIFKKKVSLLNI 855
Query: 804 ALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQT---LRADQMFPSESKQK 860
A + E PE + IE + SV N A ++K+ QT D SE +QK
Sbjct: 856 ATRITGGWKSGTEYPENLPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQK 915
Query: 861 KVEENSWDSESLRETVSQKD------------------VCVPKATHQKEMDKISGKLEDS 902
++EE + ++ + +D +C +D+ K +D
Sbjct: 916 RLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDC 975
Query: 903 TSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKV 962
L KI +T +R +L+ +HCEQ K+ ++K K VL+K++SE +EIKSQL+++ +
Sbjct: 976 VHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEIL 1035
Query: 963 KWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDI 1022
+ E+ELCS+R + QE++KRRN + +++K+RE+L EEQ+R E +V + ++ AL+ ++
Sbjct: 1036 ELEKELCSLRFAIQQEKKKRRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEV 1095
Query: 1023 ELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKI 1082
ELK+ +N NQVS T E E+ LLHEN +++ EIA L+LE T+K+Q EK KY +D +I
Sbjct: 1096 ELKTGGNNSNQVSETDEKED-LLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEI 1152
Query: 1083 LKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAEIES 1141
+K K+ +LQ LK E+L K + YSGQL L ENT L SKL K+++ ++ LE E++S
Sbjct: 1153 VKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQS 1212
Query: 1142 HHPRLASAVQDHDQIVTSRKSQEPAFHIAGDAC--LQRKMNVDVSSTIYNNEVLHQPLSE 1199
+H RL +A DHDQ +S++ QE AF D C LQ +N V +L LS+
Sbjct: 1213 YHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------ILSLQLSK 1265
Query: 1200 AQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQ 1259
A+ KS+ LK L+Y G+AL+E LV EH Q + ++ Q QMK+ E MY++ + + K E+
Sbjct: 1266 AESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEK 1325
Query: 1260 QESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF--------LERKMQHH--L 1309
QE + QL+ +NM LQQQL A KADN+ K ++I L+ + + H L
Sbjct: 1326 QE----RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHRLL 1381
Query: 1310 LKEKNEEIFNYNNHLKNRIYQYEKEKAETE 1339
L+E N+ + N NH K + QYEKEKAE E
Sbjct: 1382 LEEDNKMLVNELNHSKEKECQYEKEKAERE 1411
Score = 70.5 bits (171), Expect = 1e-11
Identities = 227/1092 (20%), Positives = 408/1092 (37%), Gaps = 142/1092 (13%)
Query: 295 EQSAEETPREITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAA 354
E E R ++S K+ + K T K I KK+ +S K + K T
Sbjct: 492 ENKDGEKSRTVSS-RKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDE 550
Query: 355 KGRPRKIAWEKKE-TPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFP 413
+ IA E K+ +T + K EK IA K+ + ++ P
Sbjct: 551 EDSVLGIARENKDGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKP 610
Query: 414 S-ESKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIE 472
S E+ +E + +S +R +K EI+R+V +KP A K +
Sbjct: 611 SLEATSDEKDSFSNITRE-----------------KKDGEISRKVSS--QKPPALKGTSD 651
Query: 473 MQNSVPNKAFELKNEQTLRA-----DPMFPPESKQKDYEEN--------------SWDSE 513
++SV A E K+ + R P S +KD N S +
Sbjct: 652 EEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQ 711
Query: 514 SLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQ 573
+ + K+ +P +K+ ++I+G + S K LKAT K S+ E+KD Q
Sbjct: 712 PALKAICDKEDSVPNMATEKKDEQISGTV--SCQKQPALKATSDKKDSVSNIPTEIKDGQ 769
Query: 574 TFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEENSWDTES 633
K A++ + + SV N A E+K+ Q + + + D E + + +
Sbjct: 770 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTGILEYTFNVMFDQIEEKFTSLN 829
Query: 634 LCETVSQKDVCLPKAAHQKEIDKIN-------GKLEGSPVKDGL--LKANCGMKVSIPTK 684
VS + K +K++ +N G G+ + L LKA K S+
Sbjct: 830 KSAGVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATIENKNSVLNT 889
Query: 685 ALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLR--ADEILPSESKQKD 742
A ++ D+QT + A E + + N ++KN+ R D+I+ S
Sbjct: 890 ATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSS----- 944
Query: 743 YEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPT 802
+ S D +SLC + K+V L ID+ K ++ C K I
Sbjct: 945 -QTVSEDGDSLC--CNCKNVILL-------IDQHEMKCKDCVHLLKIKNTFCLWKRLIKL 994
Query: 803 KALELMDMQTFKAEPPEKPSAFEPAI----EMQKSVPNKALELKNEQTLRADQMFPSESK 858
K ++ + K S + I E++ + ++ LEL+ E + + K
Sbjct: 995 KDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKK 1054
Query: 859 QKKVEE-NSWDSESLRETVSQ----KDVCVPKATHQKEMD---KISGKLEDSTS-LSKIL 909
++ VEE + E LR T Q DV P K + K G + S +
Sbjct: 1055 RRNVEEVHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKE 1114
Query: 910 DTVHSCERAR-ELQKDHCEQRTGKMEQMKKKFC----VLKKKLSEA-KEIKSQLEN---- 959
D +H + E+ + E+ T K + ++KK+ ++K+K + K +K E
Sbjct: 1115 DLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKT 1174
Query: 960 ------QKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQL 1013
Q E ++R L ++ E R+ + + L H + K+
Sbjct: 1175 IACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHDQSHSSKRDQ 1234
Query: 1014 EQALRIQDIELKSVESNLN--------QVSHTHENENYL---LHENCMLKKEIAML---- 1058
E A + + + ++ NLN Q+S L LH KE A++
Sbjct: 1235 ELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHV 1294
Query: 1059 KLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAE 1118
+ E+ + Q ++ E Y +++ + + +LK++++ + + K E
Sbjct: 1295 QSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQE 1354
Query: 1119 NTMLTSKLKEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDACLQRK 1178
+L + + + L+AE H L +D+ +V H C K
Sbjct: 1355 KAILNIQARCDARVQNLQAECRKHRLLLE---EDNKMLVNELN------HSKEKECQYEK 1405
Query: 1179 MNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQ 1238
+ + L Q + K + K L DA + E+ +D R+ Q
Sbjct: 1406 EKAEREVAVRQ---LQQKRDDVLNKGSATKALL----DASSRHCTYLENGMQDSRKKLDQ 1458
Query: 1239 MKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDI 1298
M+ Q++ + T++ E QK L+ +++ +++ + KK D++ I
Sbjct: 1459 MRSQFQEIQDQLTATIRCTKEMEGDTQK---LEVEHVMMRKII----KKQDDQ------I 1505
Query: 1299 HFLERKMQHHLL 1310
LE+ +QH L
Sbjct: 1506 ERLEKILQHSSL 1517
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 370 bits (949), Expect = e-102
Identities = 333/1068 (31%), Positives = 516/1068 (48%), Gaps = 118/1068 (11%)
Query: 307 SPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKK 366
SP K+ +EK T K IA E KE +S K+ +EK T K IA E K
Sbjct: 24 SPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIK 83
Query: 367 ETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSC 426
E ++G V+ + KV+ K + ++ T+ S S KQ + S
Sbjct: 84 EGQ-QSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGT----VSSQKQPASKTASD 138
Query: 427 DSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQNSVPNKAFELKN 486
+ S ++ +I+ + +K A K + + SV N A E+K+
Sbjct: 139 KTDSALNTATEIKDGLQCGTVSS------------QKQQALKATTDEEGSVSNIATEIKD 186
Query: 487 EQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESP 546
+K +S +L T +KD T +K+ +I+ + S
Sbjct: 187 --------------GEKSGTVSSQKKPALKATSDEKD-SFSNITREKKDGEISRTV--SS 229
Query: 547 NKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKN- 605
K LKAT + S+ A E KD + + +P + + + S+ N A K+
Sbjct: 230 QKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDG 289
Query: 606 EQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSP 665
E+T R S KQ + S K+ +P A + + ++I+G + S
Sbjct: 290 EKTRRV-----SSHKQPSLKATS-----------DKEDSVPNMATETKDEQISGTV--SC 331
Query: 666 VKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNE 725
K LKA K S+ E+ D Q +K A++ + SV N A E+K+
Sbjct: 332 QKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDG 391
Query: 726 QTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPD 785
Q I + S Q+ +L T +KD A K+ +K +G + SP
Sbjct: 392 Q------IRGTVSSQR--------RPALKTTGDEKDSVSNIAREIKDGEK-SGTV--SPQ 434
Query: 786 NDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQ 845
K + KVS+ A + E PE + IE + SV N A ++K Q
Sbjct: 435 KQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKMKEVQ 494
Query: 846 T---LRADQMFPSESKQKKVEENSWDSESLRETVSQKD------------------VCVP 884
T D SE +QK++EE + ++ + +D +C
Sbjct: 495 TSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCN 554
Query: 885 KATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLK 944
+D+ K +D L KI +T +R +L+ +HCEQ K+ ++K K VL+
Sbjct: 555 CKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQ 614
Query: 945 KKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHR 1004
K++SE +EIKSQL+++ ++ E+ELCS+R + QE++KRRN + L++K+RE+L EEQ+R
Sbjct: 615 KRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYR 674
Query: 1005 KELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIAT 1064
E +V + ++ AL+ ++ELK+ +N NQVS T E E+ LLHEN +++ EIA L+LE T
Sbjct: 675 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKED-LLHENRLMQDEIARLRLEKDT 733
Query: 1065 LKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTS 1124
+K+Q EK KY +D +I+K K+ +LQ LK E+L K + YSGQL L ENT L S
Sbjct: 734 IKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRS 791
Query: 1125 KL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDAC--LQRKMNV 1181
KL K+++ ++ LE E++S+ RL +A DHDQ +S++ QE AF D C LQ +N
Sbjct: 792 KLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNS 851
Query: 1182 DVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKE 1241
V +L LS+A+ KS+ LK L+Y G+AL+E LV EH Q + ++ Q QMK+
Sbjct: 852 HVL-------ILSLQLSKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKD 904
Query: 1242 AEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF- 1300
E MY++ + + K E+QE + QL+ +NM LQQQL A KADN+ K ++I
Sbjct: 905 IEKMYKSGYNTMEKCIEKQE----RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQAR 960
Query: 1301 -------LERKMQHH--LLKEKNEEIFNYNNHLKNRIYQYEKEKAETE 1339
L+ + + H LL+E N+ + N NH K + QYEKEKAE E
Sbjct: 961 CDARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAERE 1008
Score = 79.3 bits (194), Expect = 2e-14
Identities = 245/1160 (21%), Positives = 429/1160 (36%), Gaps = 198/1160 (17%)
Query: 280 SDKIQCLEKATSGKFEQSAEETPREI--------TSPAKETSEKFTWPAKGRPRKIAWEK 331
S + Q EKATS + S EI S K+ +EK T K IA E
Sbjct: 24 SPQKQRAEKATSDD-KDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEI 82
Query: 332 KEDTPREIMSPAKETSEKFTWAAK-------------GRPRKIAWEKKE----------- 367
KE +SP K++++K + K G+ ++ +K+
Sbjct: 83 KEGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDS 142
Query: 368 -----TPVKTGC-VARVTSNKTKVL-----EKGRSKMIACPTKESSTKASANDQRFPS-E 415
T +K G V+S K + L E+G IA K+ + + Q+ P+ +
Sbjct: 143 ALNTATEIKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALK 202
Query: 416 SKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQN 475
+ +E + +S +R +K EI+R V +KP A K ++
Sbjct: 203 ATSDEKDSFSNITRE-----------------KKDGEISRTVSS--QKPPALKATSVKED 243
Query: 476 SVPNKAFELKNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEI 535
SV N A E K+ + +S+ +E+ L T +KD L A +K+
Sbjct: 244 SVLNIAREKKDGE----------KSRTVSFEQ----PPGLKATRDEKDSLLNIARGKKDG 289
Query: 536 DKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKS 595
+K S +K LKAT + S+P A E KD Q K A + ++ + S
Sbjct: 290 EKTR---RVSSHKQPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDS 346
Query: 596 VPNKALELKNEQ----------------TLRADEILPSESKQKDYE----ENSWDTESLC 635
V N E+K+ Q +++ D + ++ KD + +S +L
Sbjct: 347 VSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALK 406
Query: 636 ETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFK 695
T +KD A K+ +K +G + SP K K KVS+ A +
Sbjct: 407 TTGDEKDSVSNIAREIKDGEK-SGTV--SPQKQSAQKVIFKKKVSLLNIATRITGGGKSG 463
Query: 696 AEPPEKPSAFEPAIEMQKSVPNKALELKNEQT---LRADEILPSESKQKDYEESSWDSES 752
E PE + IE + SV N A ++K QT D + SE +QK EE +
Sbjct: 464 TEYPENLRTLKATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQ 523
Query: 753 LCETVSQKD------------------VCLPKATHQKEIDKINGKLEESPDNDGFLKAPC 794
+ + +D +C ID+ K ++ C
Sbjct: 524 VKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFC 583
Query: 795 RMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI----EMQKSVPNKALELKNEQTLRAD 850
K I K ++ + K S + I E++ + ++ LEL+ E
Sbjct: 584 LWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRF 643
Query: 851 QMFPSESKQKKVEE-NSWDSESLRETVSQ----KDVCVPKATHQKEMD---KISGKLEDS 902
+ + K++ VEE + E LR T Q DV P K + K G +
Sbjct: 644 AIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQ 703
Query: 903 TS-LSKILDTVHSCERAR-ELQKDHCEQRTGKMEQMKKKFC----VLKKKLSEA-KEIKS 955
S + D +H + E+ + E+ T K + ++KK+ ++K+K + K +K
Sbjct: 704 VSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKR 763
Query: 956 QLEN----------QKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRK 1005
E Q E ++R L ++ E R+ + + R L H +
Sbjct: 764 NGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQ 823
Query: 1006 ELEVKQQLEQALRIQDIELKSVESNLN--------QVSHTHENENYL---LHENCMLKKE 1054
K+ E A + + + ++ NLN Q+S L LH KE
Sbjct: 824 SHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEALKE 883
Query: 1055 IAML----KLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSG 1110
A++ + E+ + Q ++ E Y +++ + + +LK++++ +
Sbjct: 884 KALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDA 943
Query: 1111 QLKVLIAENTMLTSKLKEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIA 1170
+ K E +L + + + L+AE H L +D+ +V H
Sbjct: 944 RNKADNQEKAILNIQARCDARVQNLQAECRKHRLLLE---EDNKMLVNELN------HSK 994
Query: 1171 GDACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQR 1230
C K + + L Q + K + K L DA + E+ +
Sbjct: 995 EKECQYEKEKAEREVAVRQ---LQQKRDDVLNKGSATKALL----DASSRHCTYLENGMQ 1047
Query: 1231 DQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADN 1290
D R+ QM+ Q++ + T++ E QK L+ +++ +++ + KK D+
Sbjct: 1048 DSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDTQK---LEVEHVMMRKII----KKQDD 1100
Query: 1291 KSKITIDIHFLERKMQHHLL 1310
+ I LE+ +QH L
Sbjct: 1101 Q------IERLEKILQHSSL 1114
Score = 62.4 bits (150), Expect = 3e-09
Identities = 144/665 (21%), Positives = 256/665 (38%), Gaps = 96/665 (14%)
Query: 533 KEIDKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEM 592
++I + ++E SP K KAT K S+ A E+K+ K A + ++
Sbjct: 12 QKIMPVRLRIELSPQKQRAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDE 71
Query: 593 QKSVPNKALELKNEQTLRADEILP-SESKQKDYEENSWDTESLCE---------TVSQKD 642
+ SV N A E+K Q ++ + P +S QK + ++ TVS +
Sbjct: 72 KDSVSNIATEIKEGQ--QSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQK 129
Query: 643 VCLPKAAHQKEIDKINGKLEGSPVKDGL------------LKANCGMKVSIPTKALELMD 690
K A K +N E +KDGL LKA + S+ A E+ D
Sbjct: 130 QPASKTASDKTDSALNTATE---IKDGLQCGTVSSQKQQALKATTDEEGSVSNIATEIKD 186
Query: 691 MQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQ----------------TLRADEIL 734
+ +K A + + + S N E K+ + +++ D +L
Sbjct: 187 GEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSVKEDSVL 246
Query: 735 PSESKQKDYEESSWDS----ESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFL 790
++KD E+S S L T +KD L A +K+ +K S L
Sbjct: 247 NIAREKKDGEKSRTVSFEQPPGLKATRDEKDSLLNIARGKKDGEKTR---RVSSHKQPSL 303
Query: 791 KAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRAD 850
KA + S+P A E D Q +K A + + + SV N E+K+ Q
Sbjct: 304 KATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQ----Q 359
Query: 851 QMFPSESKQKKVEENSWDSESLRETVSQ-KDVCVPKATHQKEMDKISGKLEDSTSLSKIL 909
S KQ + S +S+ ++ KD + + + ++ S+S I
Sbjct: 360 SGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRRPALKTTGDEKDSVSNI- 418
Query: 910 DTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLE---NQKVKWEQ 966
ARE+ KD + T ++ + + KKK+S I +++ ++ +
Sbjct: 419 --------AREI-KDGEKSGTVSPQKQSAQKVIFKKKVS-LLNIATRITGGGKSGTEYPE 468
Query: 967 ELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKS 1026
L +++ T+ ++ A + E + +Q LE A + L+
Sbjct: 469 NLRTLKATIENKDSVLNTATKMKEV------------QTSTPAEQDLEMASEGEQKRLEE 516
Query: 1027 VESNLNQVS---HTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKIL 1083
E+N QV H+ ++ + ++ + + ++ L + + E K + + +L
Sbjct: 517 YENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLL 576
Query: 1084 KEKNAEL--QMTLKLKE---ESLTKRASQYSGQLKVL---IAENTMLTSKLKEKQDKEIL 1135
K KN + +KLK+ E L + + + VL I+E + S+LK EIL
Sbjct: 577 KIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKH----EIL 632
Query: 1136 EAEIE 1140
E E E
Sbjct: 633 ELEKE 637
Score = 42.7 bits (99), Expect = 0.002
Identities = 154/834 (18%), Positives = 311/834 (37%), Gaps = 89/834 (10%)
Query: 249 EAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPREITSP 308
E P ++ T D +SL+ + A +G + K S K E++ + +
Sbjct: 264 EQPPGLKATRDEKDSLL----NIARGKKDGEKTRRVSSHKQPSLKATSDKEDSVPNMATE 319
Query: 309 AKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKET 368
K+ T + +P A K+D+ I + K+ + T +++ +P AW K T
Sbjct: 320 TKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQP---AW--KAT 374
Query: 369 PVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQE-EDEEYSCD 427
VK V+ + + ++ G+ + + + K + +++ S +E +D E S
Sbjct: 375 SVKKDSVSNIATE----IKDGQIRGTVSSQRRPALKTTGDEKDSVSNIAREIKDGEKSGT 430
Query: 428 SRSLFESSAKIQVCIPESIYQKVMEIN---REVEEPPKKPSAFKPAIEMQNSVPNKAFEL 484
+S+ K+ S+ I + E P+ K IE ++SV N A ++
Sbjct: 431 VSPQKQSAQKVIFKKKVSLLNIATRITGGGKSGTEYPENLRTLKATIENKDSVLNTATKM 490
Query: 485 KNEQT---LRADPMFPPESKQK---DYEENSWDSESLCETVSQKDVCLPKATHQKE---- 534
K QT D E +QK +YE N ++ + D + + E
Sbjct: 491 KEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDS 550
Query: 535 -----------IDKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPPGKP 583
ID+ K ++ + + C K I K + ++ + K
Sbjct: 551 LCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKA 610
Query: 584 SAFEPAT----EMQKSVPNKALELKNEQTLRADEILPSESKQKDYEE-NSWDTESLCETV 638
S + E++ + ++ LEL+ E I + K+++ EE + E L T
Sbjct: 611 SVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITE 670
Query: 639 SQ----KDVCLP--KAAHQKEIDKINGKLEGSPV-----KDGLLKANCGMKVSIPTKALE 687
Q DV P A E++ G + V K+ LL N M+ I LE
Sbjct: 671 EQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDEKEDLLHENRLMQDEIARLRLE 730
Query: 688 LMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTL---------RADEILPSES 738
T K + EK + I +K + +N +TL + + +
Sbjct: 731 ---KDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENT 787
Query: 739 KQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKV 798
+ E +S ET Q C A + K ++ G + ++
Sbjct: 788 TLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQE 847
Query: 799 SIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFPSESK 858
++ + L ++ +Q KAE + E + ++ KAL ++ Q+ ++ +S+
Sbjct: 848 NLNSHVL-ILSLQLSKAESKSRVLKTELHYTGE-ALKEKALVFEHVQS----ELKQKQSQ 901
Query: 859 QKKVEENSWDSESLRETVSQKD--VCVPKATH---QKEMDKISGKLEDSTSL-------- 905
K +E+ + E +K C K + Q+++D K ++
Sbjct: 902 MKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARC 961
Query: 906 -SKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKW 964
+++ + C + R L ++ + ++ K+K C +K+ +E + QL+ ++
Sbjct: 962 DARVQNLQAECRKHRLLLEEDNKMLVNELNHSKEKECQYEKEKAEREVAVRQLQQKR--- 1018
Query: 965 EQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALR 1018
+ L T + R+ L +++ ++++ + E++ QL +R
Sbjct: 1019 DDVLNKGSATKALLDASSRHCTYLENGMQDSRKKLDQMRSQFQEIQDQLTATIR 1072
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 349 bits (896), Expect = 9e-96
Identities = 271/793 (34%), Positives = 414/793 (52%), Gaps = 84/793 (10%)
Query: 582 KPSAFEPATEMQKSVPNKALELKN-EQTLRADEILPSESKQKDYEENSWDTESLCETVSQ 640
KPS + ++ + SV N A K+ E+T R S KQ + S
Sbjct: 12 KPSGLKATSDEKDSVLNIARGKKHGEKTRRV-----SSHKQP-----------ALKATSD 55
Query: 641 KDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPE 700
K+ +P A + + ++I+G + S K LKA K S+ E+ D Q +
Sbjct: 56 KENSVPNMATETKDEQISGTV--SSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQ 113
Query: 701 KPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQK 760
K A++ + SV N A E+K+ Q I + S Q+ +L T +K
Sbjct: 114 KQPAWKATSVKKDSVSNIATEIKDGQ------IRGTVSSQRQ--------PALKATGDEK 159
Query: 761 DVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEK 820
D A K+ +K +G + SP K + KVS+ A + E PE
Sbjct: 160 DSVSNIAREIKDGEK-SGTV--SPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPEN 216
Query: 821 PSAFEPAIEMQKSVPNKALELKNEQT---LRADQMFPSESKQKKVEENSWDSESLRETVS 877
+ IE + SV N A ++K+ QT D SE +QK++EE + ++ +
Sbjct: 217 LPTLKATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIH 276
Query: 878 QKD------------------VCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERAR 919
+D +C +D+ K +D L KI T C+R
Sbjct: 277 SRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLT 336
Query: 920 ELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEE 979
EL+ +HCEQ K+ ++K K VL+K+LSE +EIKSQL+++ ++ E+ELCS+R + QE+
Sbjct: 337 ELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEK 396
Query: 980 EKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHE 1039
+KRRN + L++K+RE+L EEQ+R E +V + ++ AL+ ++ELK+ +N NQVS T E
Sbjct: 397 KKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSNQVSETDE 456
Query: 1040 NENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEE 1099
E+ LLHEN +++ EIA L+LE T+K+Q EK KY +D +I+K K+ +LQ LK EE
Sbjct: 457 KED-LLHENRLMQDEIARLRLEKDTIKNQNLEK--KYLKDFEIVKRKHEDLQKALKRNEE 513
Query: 1100 SLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVT 1158
+L + + YSGQL L ENT L SKL K+++ + LE E++S+ RL +A+ DHDQ +
Sbjct: 514 TLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHS 573
Query: 1159 SRKSQEPAFHIAGDAC--LQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGD 1216
S++ QE AF D C LQ +N V +L LS+A+ K + L+ L+Y G+
Sbjct: 574 SKRDQELAFQGTVDKCCHLQENLNSHVL-------ILSLQLSKAESKFRVLETELHYTGE 626
Query: 1217 ALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMW 1276
AL+E LV EH Q + ++ Q QMK+ E MY++ + + K E+QE + QL+ +NM
Sbjct: 627 ALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQE----RFCQLKKQNML 682
Query: 1277 LQQQLVHAHKKADNKSKITIDIHF--------LERKMQHH--LLKEKNEEIFNYNNHLKN 1326
LQQQL A KADN+ K ++I L+ + + H LL+E N+ + N H K
Sbjct: 683 LQQQLDDARNKADNQEKAILNIQARCDARVENLQAECRKHRLLLEEDNKMLVNELTHSKE 742
Query: 1327 RIYQYEKEKAETE 1339
+ QYEKEKAE E
Sbjct: 743 KECQYEKEKAERE 755
Score = 52.4 bits (124), Expect = 3e-06
Identities = 171/849 (20%), Positives = 334/849 (39%), Gaps = 134/849 (15%)
Query: 399 KESSTKASANDQR-FPSESKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREV 457
K+ + KA+++ + P+ + + +DE+ S S + + K +S+ EI
Sbjct: 46 KQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKDGQ 105
Query: 458 EE---PPKKPSAFKPAIEMQNSVPNKAFELKNEQ-----TLRADPMFPPESKQKDYEENS 509
+ +K A+K ++SV N A E+K+ Q + + P +KD N
Sbjct: 106 QSGTVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSSQRQPALKATGDEKDSVSNI 165
Query: 510 W----DSESLCETVSQKDVCLPKATHQKEIDKINGKLE---------ESPNKDGLLKATC 556
D E TVS + K +K++ +N E P LKAT
Sbjct: 166 AREIKDGEK-SGTVSPQKQSAQKVIFKKKVSLLNIATRITGGWKSGTEYPENLPTLKATI 224
Query: 557 GMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTLR--ADEI 614
K S+ A ++KD+QT A E + + N ++KN+ R D+I
Sbjct: 225 ENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDDLDDI 284
Query: 615 LPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKAN 674
+ S + S D +SLC + K+V L H+ + L+ + K
Sbjct: 285 IQSS------QTVSEDGDSLC--CNCKNVILLIDQHEMKCKDCVHLLK-------IKKTF 329
Query: 675 CGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI----EMQKSVPNKALELKNEQTLRA 730
C K K ++ + K S + + E++ + ++ LEL+ E
Sbjct: 330 CLCKRLTELKDNHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLR 389
Query: 731 DEILPSESKQKDYEESSWD-SESLCETVSQ----KDVCLP--KATHQKEIDKING----- 778
I + K+++ EE E L T Q DV P A E++ G
Sbjct: 390 FAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSAEVELKTGGNNSN 449
Query: 779 KLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKA 838
++ E+ + + L M+ I LE T K + EK + I +K +
Sbjct: 450 QVSETDEKEDLLHENRLMQDEIARLRLE---KDTIKNQNLEKKYLKDFEIVKRKHEDLQK 506
Query: 839 LELKNEQTLR-------------ADQMFPSESKQKKVEENSWDSESLRETVS---QKDVC 882
+NE+TL D+ SK +K E+ E+ ++ +C
Sbjct: 507 ALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALC 566
Query: 883 VPKATHQKEMDK---ISGKLEDSTSLSKILDTVHSCERARELQKDHCEQR--------TG 931
+H + D+ G ++ L + L++ H + +L K + R TG
Sbjct: 567 DHDQSHSSKRDQELAFQGTVDKCCHLQENLNS-HVLILSLQLSKAESKFRVLETELHYTG 625
Query: 932 KMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEE----KRRNADI 987
E +K+K V + SE K+ +SQ+++ + ++ ++ + ++E K++N +
Sbjct: 626 --EALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCIEKQERFCQLKKQNM-L 682
Query: 988 LNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNL----------NQVSHT 1037
L +++ + + + Q + L ++ + + R+++++ + + L N+++H+
Sbjct: 683 LQQQLDDARNKADNQEKAILNIQARCD--ARVENLQAECRKHRLLLEEDNKMLVNELTHS 740
Query: 1038 HENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENK----------------YFED-I 1080
E E C +KE A ++ + L+ + + NK Y E+ +
Sbjct: 741 KEKE-------CQYEKEKAEREVAVRQLQQKRDDVLNKGSATKALLDASSRHCTYLENGM 793
Query: 1081 KILKEKNAELQMTLKLKEESLT---KRASQYSGQLKVLIAENTMLTSKLKEKQDKEILEA 1137
+ ++K +++ + ++ LT + + G + L EN M+ K+ +KQD++I
Sbjct: 794 QDSRKKLDQMRSQFQEIQDQLTATIRCTKEMEGDAQKLEVENVMM-RKIIKKQDEQIERF 852
Query: 1138 EIESHHPRL 1146
E H L
Sbjct: 853 EKILQHSSL 861
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 343 bits (880), Expect = 6e-94
Identities = 212/500 (42%), Positives = 300/500 (60%), Gaps = 55/500 (11%)
Query: 892 MDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAK 951
++++ + +DS SL +I DT CE +L+ +HC+Q T K++QM+ VL+ +LSE K
Sbjct: 622 IEQLRMEYKDSASLPRIQDTFCLCEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSETK 681
Query: 952 EIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQ 1011
+ K QLE QK++WE+EL +RL L QE E++RNAD+L K E+L EE+ K +E KQ
Sbjct: 682 KTKLQLELQKIEWEKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQ 741
Query: 1012 QLEQALRIQDIELKSVESNL---------------------------------------- 1031
QL+ LR EL++V +NL
Sbjct: 742 QLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARK 801
Query: 1032 ---NQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNA 1088
+++SH H+ E L HE+CML++EIA+L+LEI T+K+Q ++KE KYFEDI+ +KEKN
Sbjct: 802 KMNSEISHRHQKEKDLFHEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKND 861
Query: 1089 ELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKLKE-KQDKEILEAEIESHHPRLA 1147
LQ +KL EE+LT+ QYSGQL L AEN +L S+L+ KQ++E LE E+ES+ RLA
Sbjct: 862 NLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLA 921
Query: 1148 SAVQDHDQIVTSRKSQEPAFHIAGD-ACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKS 1206
+AV+D DQ T+R + + L KM VD+S NE+L + LS A+ K S
Sbjct: 922 AAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSEKLSNAESKINS 981
Query: 1207 LKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQK 1266
L+I L+ DAL +L+ E QRD +TQCQ KE E MYQ EQ + K+ +QES++++
Sbjct: 982 LQIQLHNTRDALGRESLILERVQRDLSQTQCQKKETEQMYQIEQSKLKKYIAKQESVEER 1041
Query: 1267 LFQLQSKNMWLQQQLVHAHKKADNKSKI--TIDIHF--------LERKMQHHLLKEKNEE 1316
L QLQS+NM L+QQL AHKKA+++ K TI F E + Q L+EKN+E
Sbjct: 1042 LSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKE 1101
Query: 1317 IFNYNNHLKNRIYQYEKEKA 1336
+ + NHLK R+ Q EKEKA
Sbjct: 1102 LMDEYNHLKERMDQCEKEKA 1121
Score = 47.4 bits (111), Expect = 9e-05
Identities = 130/707 (18%), Positives = 274/707 (38%), Gaps = 129/707 (18%)
Query: 593 QKSVPNKALELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQK 652
+++ K L + + + D+IL S+ K+ + ++E +S + HQK
Sbjct: 767 ERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSE-----ISHR--------HQK 813
Query: 653 EIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQ 712
E D L +C ++ I AL +++ T K + +K + IE
Sbjct: 814 EKD--------------LFHEDCMLQEEI---ALLRLEIDTIKNQNKQKEKKYFEDIE-- 854
Query: 713 KSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKE 772
A++ KN+ + ++ + E+L ET+ Q L T + +
Sbjct: 855 ------AVKEKNDNLQKIIKL---------------NEETLTETILQYSGQLNNLTAENK 893
Query: 773 IDKINGKLEESPDNDGFLKAP-----CRMKVSI-----PTKALEL-MDMQTFKAEPPEKP 821
I +N +LE N L+ CR+ ++ A +L +D Q + E
Sbjct: 894 I--LNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQE----- 946
Query: 822 SAFEPAIEMQKSVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDV 881
+ + V L+ KNE + ++++ +ES K+ + R+ + ++ +
Sbjct: 947 ---WVRLHDKMKVDMSGLQAKNE--ILSEKLSNAES---KINSLQIQLHNTRDALGRESL 998
Query: 882 CVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRT--GKMEQMKKK 939
++++ L + K + ++ E+++ L+K +Q + ++ Q++ +
Sbjct: 999 I---------LERVQRDLSQTQCQKKETEQMYQIEQSK-LKKYIAKQESVEERLSQLQSE 1048
Query: 940 FCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKR------RNADILNE--K 991
+L+++L +A + + E + + S L E EK+ +N ++++E
Sbjct: 1049 NMLLRQQLDDAHKKANSQEKTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNH 1108
Query: 992 IREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCML 1051
++E + + E++ + ++ + + + L E+ + Q+ T + + + L
Sbjct: 1109 LKERMDQCEKEKAGRKIDLTEAQETVPSRCLHL-DAENEVLQLQQTLFSMKAIQKQCETL 1167
Query: 1052 KKEIAMLKLEIATLKHQYQEK---ENKYFEDIKILKEKNAELQMTLKLKEESLT--KRAS 1106
+K LK E+ LK Y E+ E E K+L E+ A ++ KL E LT K+A+
Sbjct: 1168 QKNKKQLKQEVVNLK-SYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAA 1226
Query: 1107 QYSGQLKVLIAENTMLTSKLKEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPA 1166
QL L +NT K E+ ++ES R+ ++ D ++ R +
Sbjct: 1227 VSHEQLVQLREDNT-----TSIKTQMELTIKDLESEISRIKTSQADFNKTELERYKEL-- 1279
Query: 1167 FHIAGDACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSE 1226
+ E L LS + L + R +L +
Sbjct: 1280 ----------------YLEEVKVRESLSNELSRTNEMIAEVSTQLTVEKEQTRSRSLFTA 1323
Query: 1227 HAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSK 1273
+A R E+ C + N + K + ++ L ++Q K
Sbjct: 1324 YATRPVLESPCVGNLNDSEGLNRKHIPRKKRSALKDMESYLLKMQQK 1370
Score = 44.3 bits (103), Expect = 8e-04
Identities = 84/452 (18%), Positives = 178/452 (39%), Gaps = 82/452 (18%)
Query: 709 IEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKAT 768
+ +++ K L + + + D+IL S+ K+ + +SE +S +
Sbjct: 764 VVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSE-----ISHR-------- 810
Query: 769 HQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI 828
HQKE D C ++ I AL +++ T K + +K + I
Sbjct: 811 HQKEKD--------------LFHEDCMLQEEI---ALLRLEIDTIKNQNKQKEKKYFEDI 853
Query: 829 EMQKSVPN---KALELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPK 885
E K + K ++L E + + E +SE +Q+ + +
Sbjct: 854 EAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEM 913
Query: 886 ATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKK 945
+++ +++ + D D +R R+ ++ M ++ K +L +
Sbjct: 914 ESYR---CRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSE 970
Query: 946 KLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRK 1005
KLS A E ++ S+++ L+ + ++ E+++ +L + + Q +K
Sbjct: 971 KLSNA--------------ESKINSLQIQLHNTRDALGRESLILERVQRDLSQTQCQ-KK 1015
Query: 1006 ELEVKQQLEQA-LRIQDIELKSVESNLNQVSHTHENENYLLHENC-MLKKEIAMLKLEIA 1063
E E Q+EQ+ L+ + +SVE L+Q+ ++EN LL + K+ + +
Sbjct: 1016 ETEQMYQIEQSKLKKYIAKQESVEERLSQL----QSENMLLRQQLDDAHKKANSQEKTSS 1071
Query: 1064 TLKHQY------------------QEKENKYFEDIKILKEK-------NAELQMTLKLKE 1098
T++ Q+ QEK + ++ LKE+ A ++ L +
Sbjct: 1072 TIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQ 1131
Query: 1099 ESLTKRASQYSGQLKVLIAENTMLTSKLKEKQ 1130
E++ R + +VL + T+ + K +KQ
Sbjct: 1132 ETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQ 1163
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 330 bits (845), Expect = 7e-90
Identities = 199/448 (44%), Positives = 283/448 (63%), Gaps = 14/448 (3%)
Query: 900 EDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLEN 959
+D SLSK + +C R+ E QK +CE+ K ++MK VL+K LSE + KSQ E+
Sbjct: 413 KDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEH 472
Query: 960 QKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRI 1019
Q ++ +++LC++R L Q+EE+R A+ L EK EEL +EEQ+R + EVK+Q + L+
Sbjct: 473 QNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKS 532
Query: 1020 QDIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFED 1079
++ELK+V SN NQ HTHE E L EN +++ EIA L+LEI T+KHQ QE ENKYF+D
Sbjct: 533 LEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKD 592
Query: 1080 IKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAE 1138
I+I+KE N +L+ TLK EE+LTK ++YS +L VL+ ENTML S+L KEKQ LE E
Sbjct: 593 IEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETE 652
Query: 1139 IESHHPRLASAVQDHDQIVTSRKSQEPAFH-IAGDACLQRKMNVDVSSTIYNNEVLHQPL 1197
+ES+ RLA+A+ DHDQ +S++ + AF + C + D +S I ++L Q L
Sbjct: 653 MESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWC---HLQEDTNSHI---QILSQQL 706
Query: 1198 SEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHT 1257
S+A+ S L+ L+Y +AL+E TL EH Q TQ ++++ EHMYQN+Q + K+
Sbjct: 707 SKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYV 766
Query: 1258 EQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF----LERKMQHHL--LK 1311
+Q+S++ LFQLQS+N+ QQQ A KKADN+ K I+I K+Q L+
Sbjct: 767 RKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLE 826
Query: 1312 EKNEEIFNYNNHLKNRIYQYEKEKAETE 1339
E N+ + LK R QYEKEK E E
Sbjct: 827 ENNKGLMKECTLLKERQCQYEKEKEERE 854
Score = 189 bits (481), Expect = 1e-47
Identities = 107/239 (44%), Positives = 149/239 (62%), Gaps = 5/239 (2%)
Query: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANI 68
+LN +D + RTAL AC +G VV LV RKCQL++ D E+RT L+KA+QC +E CA+I
Sbjct: 64 DLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASI 123
Query: 69 LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRS 128
L++ GA+ N+ D+YGNTALHYA+ +E +S+ KLL++GA IE ++ T LLL++ ++
Sbjct: 124 LLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKK 183
Query: 129 EQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHY 188
EQ+V FLL K + A++ + TAL+LA +GS+ +V LLQ N+DVF DI G TAE Y
Sbjct: 184 EQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDY 243
Query: 189 AVTCGFHHIHEQIMEY-IRKLSKNHQNTNPEG----TSAGTPDEAAPLAERTPDTAESL 242
AV F I I EY K K+ QN+N E TS G + P E +
Sbjct: 244 AVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKM 302
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 330 bits (845), Expect = 7e-90
Identities = 199/448 (44%), Positives = 283/448 (63%), Gaps = 14/448 (3%)
Query: 900 EDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLEN 959
+D SLSK + +C R+ E QK +CE+ K ++MK VL+K LSE + KSQ E+
Sbjct: 413 KDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEH 472
Query: 960 QKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRI 1019
Q ++ +++LC++R L Q+EE+R A+ L EK EEL +EEQ+R + EVK+Q + L+
Sbjct: 473 QNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKS 532
Query: 1020 QDIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFED 1079
++ELK+V SN NQ HTHE E L EN +++ EIA L+LEI T+KHQ QE ENKYF+D
Sbjct: 533 LEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKD 592
Query: 1080 IKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAE 1138
I+I+KE N +L+ TLK EE+LTK ++YS +L VL+ ENTML S+L KEKQ LE E
Sbjct: 593 IEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETE 652
Query: 1139 IESHHPRLASAVQDHDQIVTSRKSQEPAFH-IAGDACLQRKMNVDVSSTIYNNEVLHQPL 1197
+ES+ RLA+A+ DHDQ +S++ + AF + C + D +S I ++L Q L
Sbjct: 653 MESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWC---HLQEDTNSHI---QILSQQL 706
Query: 1198 SEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHT 1257
S+A+ S L+ L+Y +AL+E TL EH Q TQ ++++ EHMYQN+Q + K+
Sbjct: 707 SKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYV 766
Query: 1258 EQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF----LERKMQHHL--LK 1311
+Q+S++ LFQLQS+N+ QQQ A KKADN+ K I+I K+Q L+
Sbjct: 767 RKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLE 826
Query: 1312 EKNEEIFNYNNHLKNRIYQYEKEKAETE 1339
E N+ + LK R QYEKEK E E
Sbjct: 827 ENNKGLMKECTLLKERQCQYEKEKEERE 854
Score = 189 bits (481), Expect = 1e-47
Identities = 107/239 (44%), Positives = 149/239 (62%), Gaps = 5/239 (2%)
Query: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANI 68
+LN +D + RTAL AC +G VV LV RKCQL++ D E+RT L+KA+QC +E CA+I
Sbjct: 64 DLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASI 123
Query: 69 LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRS 128
L++ GA+ N+ D+YGNTALHYA+ +E +S+ KLL++GA IE ++ T LLL++ ++
Sbjct: 124 LLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKK 183
Query: 129 EQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHY 188
EQ+V FLL K + A++ + TAL+LA +GS+ +V LLQ N+DVF DI G TAE Y
Sbjct: 184 EQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDY 243
Query: 189 AVTCGFHHIHEQIMEY-IRKLSKNHQNTNPEG----TSAGTPDEAAPLAERTPDTAESL 242
AV F I I EY K K+ QN+N E TS G + P E +
Sbjct: 244 AVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKM 302
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 330 bits (845), Expect = 7e-90
Identities = 199/448 (44%), Positives = 283/448 (63%), Gaps = 14/448 (3%)
Query: 900 EDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLEN 959
+D SLSK + +C R+ E QK +CE+ K ++MK VL+K LSE + KSQ E+
Sbjct: 413 KDFVSLSKSKNATAACGRSIEDQKCYCERLKVKFQKMKNNISVLQKVLSETDKTKSQSEH 472
Query: 960 QKVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRI 1019
Q ++ +++LC++R L Q+EE+R A+ L EK EEL +EEQ+R + EVK+Q + L+
Sbjct: 473 QNLQGKKKLCNLRFILQQQEEERIKAEELYEKDIEELKIMEEQYRTQTEVKKQSKLTLKS 532
Query: 1020 QDIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFED 1079
++ELK+V SN NQ HTHE E L EN +++ EIA L+LEI T+KHQ QE ENKYF+D
Sbjct: 533 LEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQNQETENKYFKD 592
Query: 1080 IKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAE 1138
I+I+KE N +L+ TLK EE+LTK ++YS +L VL+ ENTML S+L KEKQ LE E
Sbjct: 593 IEIIKENNEDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNSELQKEKQSMSRLETE 652
Query: 1139 IESHHPRLASAVQDHDQIVTSRKSQEPAFH-IAGDACLQRKMNVDVSSTIYNNEVLHQPL 1197
+ES+ RLA+A+ DHDQ +S++ + AF + C + D +S I ++L Q L
Sbjct: 653 MESYRCRLAAALCDHDQRQSSKRDLQLAFQSTVNEWC---HLQEDTNSHI---QILSQQL 706
Query: 1198 SEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHT 1257
S+A+ S L+ L+Y +AL+E TL EH Q TQ ++++ EHMYQN+Q + K+
Sbjct: 707 SKAESTSSGLETELHYEREALKEKTLHIEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYV 766
Query: 1258 EQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF----LERKMQHHL--LK 1311
+Q+S++ LFQLQS+N+ QQQ A KKADN+ K I+I K+Q L+
Sbjct: 767 RKQQSVEDGLFQLQSQNLLYQQQCNDARKKADNQEKTIINIQVKCEDTVEKLQAECRKLE 826
Query: 1312 EKNEEIFNYNNHLKNRIYQYEKEKAETE 1339
E N+ + LK R QYEKEK E E
Sbjct: 827 ENNKGLMKECTLLKERQCQYEKEKEERE 854
Score = 189 bits (480), Expect = 2e-47
Identities = 107/239 (44%), Positives = 149/239 (62%), Gaps = 5/239 (2%)
Query: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANI 68
+LN +D + RTAL AC +G VV LV RKCQL++ D E+RT L+KA+QC +E CA+I
Sbjct: 64 DLNDRDKKNRTALLLACAHGRPGVVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASI 123
Query: 69 LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRS 128
L++ GA+ N+ D+YGNTALHYA+ +E +S+ KLL++GA IE ++ T LLL++ ++
Sbjct: 124 LLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKK 183
Query: 129 EQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHY 188
EQ+V FLL K + A++ + TAL+LA +GS+ +V LLQ N+DVF DI G TAE Y
Sbjct: 184 EQMVAFLLKKKPDLTAIDNFGRTALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDY 243
Query: 189 AVTCGFHHIHEQIMEY-IRKLSKNHQNTNPEG----TSAGTPDEAAPLAERTPDTAESL 242
AV F I I EY K K+ QN+N E TS G + P E +
Sbjct: 244 AVASKFQAIRGMISEYKANKRCKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKM 302
>gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 475
Score = 312 bits (800), Expect = 1e-84
Identities = 192/454 (42%), Positives = 286/454 (62%), Gaps = 27/454 (5%)
Query: 901 DSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQ 960
D L KI +T +R +L+ +HCEQ K+ ++K K VL+K++SE +EIKSQL+++
Sbjct: 24 DCVHLLKIKNTFCLWKRLIKLKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHE 83
Query: 961 KVKWEQELCSVRLTLNQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQ 1020
++ E+ELCS+R + QE++KRRN + L++K+RE+L EEQ+R E +V + ++ AL+
Sbjct: 84 ILELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQYRIEADVTKPIKPALKSA 143
Query: 1021 DIELKSVESNLNQVSHTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDI 1080
++ELK+ +N NQVS T E E+ LLHEN +++ EIA L+L+ T+K+Q EK KY +D
Sbjct: 144 EVELKTGGNNSNQVSETDEKED-LLHENRLMQDEIARLRLDTDTIKNQNLEK--KYLKDF 200
Query: 1081 KILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAEI 1139
+I+K K+ +LQ LK E+L K + YSGQL L ENT L SKL K+++ ++ LE E+
Sbjct: 201 EIVKRKHEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEM 260
Query: 1140 ESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDAC--LQRKMNVDVSSTIYNNEVLHQPL 1197
+S+H RL +A DHDQ +S++ QE AF D C LQ +N V +L L
Sbjct: 261 QSYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVL-------ILSLQL 313
Query: 1198 SEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHT 1257
S+A+ KS+ LK L+Y G+AL+E LV EH Q + ++ Q QMK+ E MY++ + + K
Sbjct: 314 SKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQMKDIEKMYKSGYNTMEKCI 373
Query: 1258 EQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSKITIDIHF--------LERKMQHH- 1308
E+QE + QL+ +NM LQQQL A KADN+ K ++I L+ + + H
Sbjct: 374 EKQE----RFCQLKKQNMLLQQQLDDARNKADNQEKAILNIQARCDARVQNLQAECRKHR 429
Query: 1309 -LLKEKNEEIFNYNNHLKNRIYQYEKEKAETENS 1341
LL+E N+ + N NH K + QYEKEKAE E S
Sbjct: 430 LLLEEDNKMLVNELNHSKEKECQYEKEKAEREVS 463
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 295 bits (756), Expect = 2e-79
Identities = 192/529 (36%), Positives = 290/529 (54%), Gaps = 57/529 (10%)
Query: 817 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFP--SESKQKKVEENSWDSESLRE 874
PP K + +P+ EM+ A++ KN QTLRA+Q P SE +Q++ E R
Sbjct: 328 PPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRE---------RS 378
Query: 875 TVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKME 934
Q V T++ E ++S + ST
Sbjct: 379 EKKQPQVIEGNNTYKSEKIQLSENICHST------------------------------- 407
Query: 935 QMKKKFCVLKKKLSEAKEIKSQLENQ---KVKWEQELCSVRLTLNQEEEKRRNADILNEK 991
F +L++ ++I Q K+K E + C TL QE E++ N ++L++K
Sbjct: 408 -----FSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENEEKTNVNMLHKK 458
Query: 992 IREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCML 1051
REEL R E+Q++KE+E KQ LE ++ +++ K+ + NQ H HE L+ ENC+L
Sbjct: 459 NREELERKEKQYKKEVEAKQ-LEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCIL 517
Query: 1052 KKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQ 1111
K +IA+L+ EI T+K+ EKENKY +DIKI KE NA L+ +KL EE +TK A Y +
Sbjct: 518 KTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQE 577
Query: 1112 LKVLIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIA 1170
L L AENT L S+L KEK+ K+ LEAEIES+ RLA+A+ H + V + ++ + A
Sbjct: 578 LNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERT 637
Query: 1171 GDACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQR 1230
D Q KM+ D+S N L + LS+ Q K +LK D LR+ +L E Q
Sbjct: 638 QDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQN 697
Query: 1231 DQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADN 1290
D +TQ Q+KE + MYQ+ + V+K T + +++++ QLQ +N WL+QQLV H+K D+
Sbjct: 698 DLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDH 757
Query: 1291 KS-KITIDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAET 1338
K I I F+E + + +L+EKN+++ N +HLK ++QYE++KAET
Sbjct: 758 KEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQYERQKAET 806
Score = 213 bits (542), Expect = 1e-54
Identities = 111/225 (49%), Positives = 158/225 (70%), Gaps = 6/225 (2%)
Query: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
+++ +L+ D Q RTALH AC +GH +VVT LV+RKCQ+D+ D E+RTPL++A+ C +EA
Sbjct: 55 RRSGDLDALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEA 114
Query: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSI 124
CA IL++ GA+ NL D+YGNTALHYAVYSE S+ KLL HG IE +K S TPLL +I
Sbjct: 115 CAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAI 174
Query: 125 TKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVT 184
+ E++VEFLL A+ +AV++ + TALMLAV + S IV +LL+Q+++VF D+CG
Sbjct: 175 ICKKEKMVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRD 234
Query: 185 AEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAA 229
AE YA++C I +QI+E+ + + KN + G+ DE+A
Sbjct: 235 AEDYAISCRLTKIQQQILEHKKMILKN------DKPDVGSSDESA 273
Score = 66.6 bits (161), Expect = 2e-10
Identities = 115/528 (21%), Positives = 205/528 (38%), Gaps = 66/528 (12%)
Query: 579 PPGKPSAFEPATEMQKSVPNKALELKNEQTLRADEILP--SESKQKDYEENSWDTESLCE 636
PP K + +P+TEM+ A++ KN QTLRA++ LP SE +Q+ E + + E
Sbjct: 328 PPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQVIE 387
Query: 637 ---TVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQT 693
T + + L + +L K P K E D T
Sbjct: 388 GNNTYKSEKIQLSENICHSTFSAAADRLTQQ------RKIGKTYPQQFPKKLKEEHDRCT 441
Query: 694 FKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESL 753
K E EK + L KN + L E K+K Y++ +++ L
Sbjct: 442 LKQENEEKTNV-------------NMLHKKNREEL--------ERKEKQYKKEV-EAKQL 479
Query: 754 CETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTF 813
TV ++ A + D N EE D + C +K I A+ ++ T
Sbjct: 480 EPTVQSLEMKPKTARNTPNQDFHNH--EEVKD---LMDENCILKTDI---AILRQEICTM 531
Query: 814 KAEPPEKPSAFEPAIEMQK---SVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSE 870
K + EK + + I++ K + K ++L E + + E K E +SE
Sbjct: 532 KNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSE 591
Query: 871 SLRETVSQKDVCVPKATHQKEM----DKISGKLEDSTSLSKILDTVHSCERARELQKDHC 926
L+E S+K + ++Q + K S ++ +L L+ ++ D
Sbjct: 592 LLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDIS 651
Query: 927 EQR------TGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEE 980
E T ++ +M+ KF LK K + ++ + + +L + + + +E
Sbjct: 652 EIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKE 711
Query: 981 KRRNADILNEKIREELGRIEEQ----HRKELEVKQQLEQALRIQDIELKSVESNLNQVSH 1036
++A+ K + +EE+ R+ ++QQL + +D K + N+ +
Sbjct: 712 MYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKED--HKEIVINIQRGFI 769
Query: 1037 THENENYLLHE-NCMLKKEIAMLKLEIATLKHQYQE-----KENKYFE 1078
++ +L E N L E LK + + Q E KE+KYF+
Sbjct: 770 ESRKKDLMLEEKNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQ 817
Score = 61.2 bits (147), Expect = 6e-09
Identities = 136/620 (21%), Positives = 229/620 (36%), Gaps = 90/620 (14%)
Query: 377 RVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFES-- 434
R+T + ++LE KMI K ++D ES E DS S +
Sbjct: 243 RLTKIQQQILE--HKKMIL---KNDKPDVGSSD-----ESAVSIFHELCVDSLSALDDEL 292
Query: 435 -SAKIQVCIPESIYQKVME---------INREVEEPPKKPSAFKPAIEMQNSVPNKAFEL 484
S + C+PE + + + +N + E PP K + KP+ EM++ A +
Sbjct: 293 LSVAAKQCVPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQX 352
Query: 485 KNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEE 544
KN QTLRA+ P S+++ + + Q V T++ E +++ +
Sbjct: 353 KNVQTLRAEQALPVASEEEQQRRERSEKK-------QPQVIEGNNTYKSEKIQLSENICH 405
Query: 545 SPNKDGLLKATCGMKV------SIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPN 598
S + T K+ P K E D T K E K +
Sbjct: 406 STFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV------------- 452
Query: 599 KALELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKIN 658
L KN + L E K+K Y++ + + L TV ++ PK A +
Sbjct: 453 NMLHKKNREEL--------ERKEKQYKKEV-EAKQLEPTVQSLEM-KPKTARNTPNQDFH 502
Query: 659 GKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQK---SV 715
E VKD L+ NC +K I A+ ++ T K + EK + + I++ K +
Sbjct: 503 NHEE---VKD-LMDENCILKTDI---AILRQEICTMKNDNLEKENKYLKDIKIAKETNAA 555
Query: 716 PNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDK 775
K ++L E + E E + +SE L E S+K + ++Q +
Sbjct: 556 LEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAA 615
Query: 776 INGKLEESPDNDGFLKAPCRM------KVSIPTKALELMDMQTFKAEPPEKPSAFEPAIE 829
K E+ + LK +V + + E+ D F E K
Sbjct: 616 AISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQI------ 669
Query: 830 MQKSVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQ 889
K K K TLR + E+ Q + + + ++E + V K+T +
Sbjct: 670 --KFNTLKDKFRKTRDTLRKKSL-ALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGK 726
Query: 890 KEM--DKISGKLEDSTSLSKILDTVHSCERARE----LQKDHCEQRTGKMEQMKKKFCVL 943
++I ++ L + L VH E +E +Q+ E R K +++K L
Sbjct: 727 WNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRK-KDLMLEEKNKKL 785
Query: 944 KKKLSEAKEIKSQLENQKVK 963
+ KE Q E QK +
Sbjct: 786 MNEYDHLKESLFQYERQKAE 805
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 295 bits (756), Expect = 2e-79
Identities = 192/529 (36%), Positives = 290/529 (54%), Gaps = 57/529 (10%)
Query: 817 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFP--SESKQKKVEENSWDSESLRE 874
PP K + +P+ EM+ A++ KN QTLRA+Q P SE +Q++ E R
Sbjct: 328 PPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRE---------RS 378
Query: 875 TVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKME 934
Q V T++ E ++S + ST
Sbjct: 379 EKKQPQVIEGNNTYKSEKIQLSENICHST------------------------------- 407
Query: 935 QMKKKFCVLKKKLSEAKEIKSQLENQ---KVKWEQELCSVRLTLNQEEEKRRNADILNEK 991
F +L++ ++I Q K+K E + C TL QE E++ N ++L++K
Sbjct: 408 -----FSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENEEKTNVNMLHKK 458
Query: 992 IREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCML 1051
REEL R E+Q++KE+E KQ LE ++ +++ K+ + NQ H HE L+ ENC+L
Sbjct: 459 NREELERKEKQYKKEVEAKQ-LEPTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCIL 517
Query: 1052 KKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQ 1111
K +IA+L+ EI T+K+ EKENKY +DIKI KE NA L+ +KL EE +TK A Y +
Sbjct: 518 KTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQE 577
Query: 1112 LKVLIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIA 1170
L L AENT L S+L KEK+ K+ LEAEIES+ RLA+A+ H + V + ++ + A
Sbjct: 578 LNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERT 637
Query: 1171 GDACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQR 1230
D Q KM+ D+S N L + LS+ Q K +LK D LR+ +L E Q
Sbjct: 638 QDISEQVKMSSDISEIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQN 697
Query: 1231 DQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADN 1290
D +TQ Q+KE + MYQ+ + V+K T + +++++ QLQ +N WL+QQLV H+K D+
Sbjct: 698 DLSQTQQQIKEMKEMYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDH 757
Query: 1291 KS-KITIDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAET 1338
K I I F+E + + +L+EKN+++ N +HLK ++QYE++KAET
Sbjct: 758 KEIVINIQRGFIESRKKDLMLEEKNKKLMNEYDHLKESLFQYERQKAET 806
Score = 213 bits (542), Expect = 1e-54
Identities = 111/225 (49%), Positives = 158/225 (70%), Gaps = 6/225 (2%)
Query: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
+++ +L+ D Q RTALH AC +GH +VVT LV+RKCQ+D+ D E+RTPL++A+ C +EA
Sbjct: 55 RRSGDLDALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEA 114
Query: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSI 124
CA IL++ GA+ NL D+YGNTALHYAVYSE S+ KLL HG IE +K S TPLL +I
Sbjct: 115 CAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAI 174
Query: 125 TKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVT 184
+ E++VEFLL A+ +AV++ + TALMLAV + S IV +LL+Q+++VF D+CG
Sbjct: 175 ICKKEKMVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRD 234
Query: 185 AEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAA 229
AE YA++C I +QI+E+ + + KN + G+ DE+A
Sbjct: 235 AEDYAISCRLTKIQQQILEHKKMILKN------DKPDVGSSDESA 273
Score = 66.6 bits (161), Expect = 2e-10
Identities = 115/528 (21%), Positives = 205/528 (38%), Gaps = 66/528 (12%)
Query: 579 PPGKPSAFEPATEMQKSVPNKALELKNEQTLRADEILP--SESKQKDYEENSWDTESLCE 636
PP K + +P+TEM+ A++ KN QTLRA++ LP SE +Q+ E + + E
Sbjct: 328 PPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQVIE 387
Query: 637 ---TVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQT 693
T + + L + +L K P K E D T
Sbjct: 388 GNNTYKSEKIQLSENICHSTFSAAADRLTQQ------RKIGKTYPQQFPKKLKEEHDRCT 441
Query: 694 FKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESL 753
K E EK + L KN + L E K+K Y++ +++ L
Sbjct: 442 LKQENEEKTNV-------------NMLHKKNREEL--------ERKEKQYKKEV-EAKQL 479
Query: 754 CETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTF 813
TV ++ A + D N EE D + C +K I A+ ++ T
Sbjct: 480 EPTVQSLEMKPKTARNTPNQDFHNH--EEVKD---LMDENCILKTDI---AILRQEICTM 531
Query: 814 KAEPPEKPSAFEPAIEMQK---SVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSE 870
K + EK + + I++ K + K ++L E + + E K E +SE
Sbjct: 532 KNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSE 591
Query: 871 SLRETVSQKDVCVPKATHQKEM----DKISGKLEDSTSLSKILDTVHSCERARELQKDHC 926
L+E S+K + ++Q + K S ++ +L L+ ++ D
Sbjct: 592 LLKEKESKKKLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDIS 651
Query: 927 EQR------TGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEE 980
E T ++ +M+ KF LK K + ++ + + +L + + + +E
Sbjct: 652 EIEDKNXFLTEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKE 711
Query: 981 KRRNADILNEKIREELGRIEEQ----HRKELEVKQQLEQALRIQDIELKSVESNLNQVSH 1036
++A+ K + +EE+ R+ ++QQL + +D K + N+ +
Sbjct: 712 MYQSAEAKVSKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKED--HKEIVINIQRGFI 769
Query: 1037 THENENYLLHE-NCMLKKEIAMLKLEIATLKHQYQE-----KENKYFE 1078
++ +L E N L E LK + + Q E KE+KYF+
Sbjct: 770 ESRKKDLMLEEKNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQ 817
Score = 61.2 bits (147), Expect = 6e-09
Identities = 136/620 (21%), Positives = 229/620 (36%), Gaps = 90/620 (14%)
Query: 377 RVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFES-- 434
R+T + ++LE KMI K ++D ES E DS S +
Sbjct: 243 RLTKIQQQILE--HKKMIL---KNDKPDVGSSD-----ESAVSIFHELCVDSLSALDDEL 292
Query: 435 -SAKIQVCIPESIYQKVME---------INREVEEPPKKPSAFKPAIEMQNSVPNKAFEL 484
S + C+PE + + + +N + E PP K + KP+ EM++ A +
Sbjct: 293 LSVAAKQCVPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQX 352
Query: 485 KNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEE 544
KN QTLRA+ P S+++ + + Q V T++ E +++ +
Sbjct: 353 KNVQTLRAEQALPVASEEEQQRRERSEKK-------QPQVIEGNNTYKSEKIQLSENICH 405
Query: 545 SPNKDGLLKATCGMKV------SIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPN 598
S + T K+ P K E D T K E K +
Sbjct: 406 STFSAAADRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV------------- 452
Query: 599 KALELKNEQTLRADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKIN 658
L KN + L E K+K Y++ + + L TV ++ PK A +
Sbjct: 453 NMLHKKNREEL--------ERKEKQYKKEV-EAKQLEPTVQSLEM-KPKTARNTPNQDFH 502
Query: 659 GKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQK---SV 715
E VKD L+ NC +K I A+ ++ T K + EK + + I++ K +
Sbjct: 503 NHEE---VKD-LMDENCILKTDI---AILRQEICTMKNDNLEKENKYLKDIKIAKETNAA 555
Query: 716 PNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDK 775
K ++L E + E E + +SE L E S+K + ++Q +
Sbjct: 556 LEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAA 615
Query: 776 INGKLEESPDNDGFLKAPCRM------KVSIPTKALELMDMQTFKAEPPEKPSAFEPAIE 829
K E+ + LK +V + + E+ D F E K
Sbjct: 616 AISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFLTEQLSKMQI------ 669
Query: 830 MQKSVPNKALELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQ 889
K K K TLR + E+ Q + + + ++E + V K+T +
Sbjct: 670 --KFNTLKDKFRKTRDTLRKKSL-ALETVQNDLSQTQQQIKEMKEMYQSAEAKVSKSTGK 726
Query: 890 KEM--DKISGKLEDSTSLSKILDTVHSCERARE----LQKDHCEQRTGKMEQMKKKFCVL 943
++I ++ L + L VH E +E +Q+ E R K +++K L
Sbjct: 727 WNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRK-KDLMLEEKNKKL 785
Query: 944 KKKLSEAKEIKSQLENQKVK 963
+ KE Q E QK +
Sbjct: 786 MNEYDHLKESLFQYERQKAE 805
>gi|239744894 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383069 [Homo sapiens]
Length = 197
Score = 293 bits (749), Expect = 1e-78
Identities = 148/194 (76%), Positives = 167/194 (86%), Gaps = 2/194 (1%)
Query: 4 RKKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQE 63
+K T++ NI+DA+KRTALHWAC NGH EVVT LVDRKCQLDVLDGE+ TPLMKA+QC +E
Sbjct: 3 KKTTMDPNIRDAKKRTALHWACANGHAEVVTLLVDRKCQLDVLDGENGTPLMKAVQCQRE 62
Query: 64 ACANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLS 123
CANILIDSGAD N+VDVY NTA+HYAVY E LSVVAKLLS GA I+V NKA TPLLL+
Sbjct: 63 VCANILIDSGADPNIVDVYVNTAVHYAVYGENLSVVAKLLSCGADIKVKNKAGHTPLLLA 122
Query: 124 ITKRSEQIVEFLLIKNANANA--VNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADIC 181
I KRSEQIVEFLL KNANANA V+K+KCTALMLA+CHGSSEIVGM+LQQNVD+ A D C
Sbjct: 123 IRKRSEQIVEFLLTKNANANANSVDKFKCTALMLAICHGSSEIVGMVLQQNVDICAVDTC 182
Query: 182 GVTAEHYAVTCGFH 195
G+ AE YAV CGF+
Sbjct: 183 GMIAERYAVACGFN 196
>gi|239757617 PREDICTED: similar to hCG1793014 [Homo sapiens]
Length = 251
Score = 287 bits (734), Expect = 5e-77
Identities = 143/192 (74%), Positives = 164/192 (85%)
Query: 4 RKKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQE 63
+K T++LNI+DA+KRTALHWAC NG EVVT LVDRKCQLD+LDGE+RT LMKA+QC +E
Sbjct: 59 KKTTMDLNIRDAKKRTALHWACANGRAEVVTLLVDRKCQLDILDGENRTTLMKAVQCQRE 118
Query: 64 ACANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLS 123
CANILIDSGAD N+VDVYGNTA+HYA+ E LSVVAKLLS GA IEV NK TPLLL
Sbjct: 119 VCANILIDSGADPNIVDVYGNTAVHYALIGENLSVVAKLLSCGADIEVKNKTGHTPLLLV 178
Query: 124 ITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGV 183
+ KRSEQIVEFLL KNANANAV+K+KCTALMLA+CHGSSEIVGM+LQ+NVD+ A D G+
Sbjct: 179 MRKRSEQIVEFLLTKNANANAVDKFKCTALMLAMCHGSSEIVGMVLQENVDICAEDTWGM 238
Query: 184 TAEHYAVTCGFH 195
AE YAV CGF+
Sbjct: 239 IAERYAVACGFN 250
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sapiens]
Length = 823
Score = 284 bits (727), Expect = 4e-76
Identities = 186/525 (35%), Positives = 289/525 (55%), Gaps = 51/525 (9%)
Query: 817 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFP--SESKQKKVEENSWDSESLRE 874
PP K + +P+ E++ A++ KN QTLRA+Q P SE +Q++ E R
Sbjct: 328 PPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHE---------RS 378
Query: 875 TVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKME 934
Q V T++ E ++S + DSTS + G++
Sbjct: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAA----------------------AGRLT 416
Query: 935 QMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIRE 994
Q +K K Q +K+K E + C TL QE E++ N ++L +K RE
Sbjct: 417 QQRKI----------GKTYPQQFP-KKLKEEHDRC----TLKQENEEKTNVNMLYKKNRE 461
Query: 995 ELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKE 1054
EL R E+Q++KE+E KQ LE ++ +++ K+ + N+ H HE L+ ENC+LK +
Sbjct: 462 ELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKAD 520
Query: 1055 IAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKV 1114
IA+L+ EI T+K+ EKENKY +DIKI+KE NA L+ +KL EE +T+ A +Y +L
Sbjct: 521 IAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNY 580
Query: 1115 LIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDA 1173
L AENT L ++L KEK+ K+ LEA+IES+ RLA+A+ H + V + ++ + A D
Sbjct: 581 LKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDV 640
Query: 1174 CLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQR 1233
+Q +M+ +S NE L + LSE Q K +LK D+LR+ +L E Q D
Sbjct: 641 SVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLS 700
Query: 1234 ETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSK 1293
+TQ Q +E + MYQN + VN T + +++++ LQ +N WL QQL H+K D+K
Sbjct: 701 QTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEI 760
Query: 1294 IT-IDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAE 1337
+T I F+E + +L+EK++++ N +HLK ++QYE+EK E
Sbjct: 761 VTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTE 805
Score = 225 bits (574), Expect = 2e-58
Identities = 167/499 (33%), Positives = 256/499 (51%), Gaps = 63/499 (12%)
Query: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
+++ +L+ D Q RTALH AC +GH +VVT LV+RKCQ+DV D E+RTPL++A+ C +EA
Sbjct: 55 RRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEA 114
Query: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSI 124
CA IL++ GA+ NL D+YGNTALHYAVYSE S+ KLLSHGA IE +K + TPLL +I
Sbjct: 115 CAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAI 174
Query: 125 TKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVT 184
+ E++VEFLL + A+++AV++ + +ALMLAV + S IV +LL+QN+DVFA D+CG
Sbjct: 175 ICKKEKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRD 234
Query: 185 AEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVE 244
AE YA++ I +QI+E+ +K+ K E + G+ DE +A S+
Sbjct: 235 AEDYAISHHLTKIQQQILEHKKKILKK------EKSDVGSSDE----------SAVSIFH 278
Query: 245 KTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPRE 304
+ ++ P + D + + P++ + + G+S + + E P
Sbjct: 279 ELRVDSLPASD-DKDLNVATKQCVPEKVSEPLPGSSHE-------KGNRIVNGQGEGP-- 328
Query: 305 ITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWE 364
PAK S K + + K A ++K SE + + R E
Sbjct: 329 ---PAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASE------EEQERHERSE 379
Query: 365 KKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQR---------FPSE 415
KK+ VK G N T EK + C + S+ QR FP +
Sbjct: 380 KKQPQVKEG-------NNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKK 432
Query: 416 SKQEEDEEYSCDSRSLFESSAKIQVCIP---ESIYQKVMEINREVEEPPKKPSAFKPAIE 472
K+E D C + E + + E + +K + +EVE +P+ ++E
Sbjct: 433 LKEEHDR---CTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTV--QSLE 487
Query: 473 MQN----SVPNKAFELKNE 487
M++ + PN+ F E
Sbjct: 488 MKSKTARNTPNRDFHNHEE 506
Score = 55.1 bits (131), Expect = 5e-07
Identities = 122/602 (20%), Positives = 234/602 (38%), Gaps = 76/602 (12%)
Query: 377 RVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFESSA 436
++ +K K+L+K +S + + + S + ++ R S ++ + + + E
Sbjct: 250 QILEHKKKILKKEKSDV---GSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE--- 303
Query: 437 KIQVCIPESIYQKVMEI-NREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPM 495
K+ +P S ++K I N + E PP K + KP+ E+++ A + KN QTLRA+
Sbjct: 304 KVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQA 363
Query: 496 FPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKAT 555
P S+++ +E SE Q V T++ E +++ + +S + + T
Sbjct: 364 LPVASEEE--QERHERSEK-----KQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLT 416
Query: 556 CGMKV------SIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTL 609
K+ P K E D T K E K + L KN + L
Sbjct: 417 QQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------NMLYKKNREEL 463
Query: 610 RADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDG 669
E K+K Y++ + + L TV ++ A + D N + G
Sbjct: 464 --------ERKEKQYKKEV-EAKQLEPTVQSLEMKSKTARNTPNRDFHNHE-----EMKG 509
Query: 670 LLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLR 729
L+ NC +K I E+ M+ E K ++ + K ++L E
Sbjct: 510 LMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569
Query: 730 ADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGF 789
E E + ++E L E S+K + ++Q + K ES +
Sbjct: 570 TAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERN 629
Query: 790 LKAPCR------MKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI-----EMQKSVPNKA 838
LK ++V + + ++ D F E + A+ + + S+ K+
Sbjct: 630 LKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKS 689
Query: 839 LELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDKISGK 898
L L+ Q + + ++ + ++++E ++E+ + K CV ++I
Sbjct: 690 LALETVQ----NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVE--------ERICHL 737
Query: 899 LEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCV---LKKKLSEAKEIKS 955
++ L + LD VH E +E+ + + G +E KK + KK ++E +K
Sbjct: 738 QRENAWLVQQLDDVHQKEDHKEIVTN---IQRGFIESGKKDLVLEEKSKKLMNECDHLKE 794
Query: 956 QL 957
L
Sbjct: 795 SL 796
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sapiens]
Length = 823
Score = 283 bits (725), Expect = 6e-76
Identities = 186/525 (35%), Positives = 289/525 (55%), Gaps = 51/525 (9%)
Query: 817 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFP--SESKQKKVEENSWDSESLRE 874
PP K + +P+ E++ A++ KN QTLRA+Q P SE +Q++ E R
Sbjct: 328 PPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHE---------RS 378
Query: 875 TVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKME 934
Q V T++ E ++S + DSTS + G++
Sbjct: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAA----------------------AGRLT 416
Query: 935 QMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIRE 994
Q +K K Q +K+K E + C TL QE E++ N ++L +K RE
Sbjct: 417 QQRKI----------GKTYPQQFP-KKLKEEHDRC----TLKQENEEKTNVNMLYKKNRE 461
Query: 995 ELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKE 1054
EL R E+Q++KE+E KQ LE ++ +++ K+ + N+ H HE L+ ENC+LK +
Sbjct: 462 ELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKAD 520
Query: 1055 IAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKV 1114
IA+L+ EI T+K+ EKENKY +DIKI+KE NA L+ +KL EE +T+ A +Y +L
Sbjct: 521 IAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELND 580
Query: 1115 LIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDA 1173
L AENT L ++L KEK+ K+ LEA+IES+ RLA+A+ H + V + ++ + A D
Sbjct: 581 LKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDV 640
Query: 1174 CLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQR 1233
+Q +M+ +S NE L + LSE Q K +LK D+LR+ +L E Q D
Sbjct: 641 SVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLS 700
Query: 1234 ETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSK 1293
+TQ Q +E + MYQN + VN T + +++++ LQ +N WL QQL H+K D+K
Sbjct: 701 QTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEI 760
Query: 1294 IT-IDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAE 1337
+T I F+E + +L+EK++++ N +HLK ++QYE+EK E
Sbjct: 761 VTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTE 805
Score = 225 bits (574), Expect = 2e-58
Identities = 167/499 (33%), Positives = 256/499 (51%), Gaps = 63/499 (12%)
Query: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
+++ +L+ D Q RTALH AC +GH +VVT LV+RKCQ+DV D E+RTPL++A+ C +EA
Sbjct: 55 RRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEA 114
Query: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSI 124
CA IL++ GA+ NL D+YGNTALHYAVYSE S+ KLLSHGA IE +K + TPLL +I
Sbjct: 115 CAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAI 174
Query: 125 TKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVT 184
+ E++VEFLL + A+++AV++ + +ALMLAV + S IV +LL+QN+DVFA D+CG
Sbjct: 175 ICKKEKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRD 234
Query: 185 AEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVE 244
AE YA++ I +QI+E+ +K+ K E + G+ DE +A S+
Sbjct: 235 AEDYAISHHLTKIQQQILEHKKKILKK------EKSDVGSSDE----------SAVSIFH 278
Query: 245 KTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPRE 304
+ ++ P + D + + P++ + + G+S + + E P
Sbjct: 279 ELRVDSLPASD-DKDLNVATKQCVPEKVSEPLPGSSHE-------KGNRIVNGQGEGP-- 328
Query: 305 ITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWE 364
PAK S K + + K A ++K SE + + R E
Sbjct: 329 ---PAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASE------EEQERHERSE 379
Query: 365 KKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQR---------FPSE 415
KK+ VK G N T EK + C + S+ QR FP +
Sbjct: 380 KKQPQVKEG-------NNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKK 432
Query: 416 SKQEEDEEYSCDSRSLFESSAKIQVCIP---ESIYQKVMEINREVEEPPKKPSAFKPAIE 472
K+E D C + E + + E + +K + +EVE +P+ ++E
Sbjct: 433 LKEEHDR---CTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTV--QSLE 487
Query: 473 MQN----SVPNKAFELKNE 487
M++ + PN+ F E
Sbjct: 488 MKSKTARNTPNRDFHNHEE 506
Score = 55.5 bits (132), Expect = 3e-07
Identities = 122/602 (20%), Positives = 234/602 (38%), Gaps = 76/602 (12%)
Query: 377 RVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFESSA 436
++ +K K+L+K +S + + + S + ++ R S ++ + + + E
Sbjct: 250 QILEHKKKILKKEKSDV---GSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE--- 303
Query: 437 KIQVCIPESIYQKVMEI-NREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPM 495
K+ +P S ++K I N + E PP K + KP+ E+++ A + KN QTLRA+
Sbjct: 304 KVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQA 363
Query: 496 FPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKAT 555
P S+++ +E SE Q V T++ E +++ + +S + + T
Sbjct: 364 LPVASEEE--QERHERSEK-----KQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLT 416
Query: 556 CGMKV------SIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTL 609
K+ P K E D T K E K + L KN + L
Sbjct: 417 QQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------NMLYKKNREEL 463
Query: 610 RADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDG 669
E K+K Y++ + + L TV ++ A + D N + G
Sbjct: 464 --------ERKEKQYKKEV-EAKQLEPTVQSLEMKSKTARNTPNRDFHNHE-----EMKG 509
Query: 670 LLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLR 729
L+ NC +K I E+ M+ E K ++ + K ++L E
Sbjct: 510 LMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569
Query: 730 ADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGF 789
E E + ++E L E S+K + ++Q + K ES +
Sbjct: 570 TAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERN 629
Query: 790 LKAPCR------MKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI-----EMQKSVPNKA 838
LK ++V + + ++ D F E + A+ + + S+ K+
Sbjct: 630 LKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKS 689
Query: 839 LELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDKISGK 898
L L+ Q + + ++ + ++++E ++E+ + K CV ++I
Sbjct: 690 LALETVQ----NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVE--------ERICHL 737
Query: 899 LEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCV---LKKKLSEAKEIKS 955
++ L + LD VH E +E+ + + G +E KK + KK ++E +K
Sbjct: 738 QRENAWLVQQLDDVHQKEDHKEIVTN---IQRGFIESGKKDLVLEEKSKKLMNECDHLKE 794
Query: 956 QL 957
L
Sbjct: 795 SL 796
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 283 bits (723), Expect = 1e-75
Identities = 186/525 (35%), Positives = 288/525 (54%), Gaps = 51/525 (9%)
Query: 817 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFP--SESKQKKVEENSWDSESLRE 874
PP K + +P+ E++ A++ KN QTLRA+Q P SE +Q++ E R
Sbjct: 328 PPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHE---------RS 378
Query: 875 TVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKME 934
Q V T++ E ++S + DSTS + G++
Sbjct: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAA----------------------AGRLT 416
Query: 935 QMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIRE 994
Q +K K Q +K+K E + C TL QE E++ N ++L +K RE
Sbjct: 417 QQRKI----------GKTYPQQFP-KKLKEEHDRC----TLKQENEEKTNVNMLYKKNRE 461
Query: 995 ELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKE 1054
EL R E+Q++KE+E KQ LE ++ +++ K+ + N H HE L+ ENC+LK +
Sbjct: 462 ELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKAD 520
Query: 1055 IAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKV 1114
IA+L+ EI T+K+ EKENKY +DIKI+KE NA L+ +KL EE +T+ A +Y +L
Sbjct: 521 IAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELND 580
Query: 1115 LIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDA 1173
L AENT L ++L KEK+ K+ LEA+IES+ RLA+A+ H + V + ++ + A D
Sbjct: 581 LKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDV 640
Query: 1174 CLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQR 1233
+Q +M+ +S NE L + LSE Q K +LK D+LR+ +L E Q D
Sbjct: 641 SVQVEMSSAISKVKAENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLS 700
Query: 1234 ETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSK 1293
+TQ Q +E + MYQN + VN T + +++++ LQ +N WL QQL H+K D+K
Sbjct: 701 QTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEI 760
Query: 1294 IT-IDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAE 1337
+T I F+E + +L+EK++++ N +HLK ++QYE+EK E
Sbjct: 761 VTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTE 805
Score = 225 bits (573), Expect = 3e-58
Identities = 171/500 (34%), Positives = 258/500 (51%), Gaps = 67/500 (13%)
Query: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
+++ +L+ D Q RTALH AC +GH +VVT LV+RKCQ+DV D E+RTPL++A+ C +EA
Sbjct: 55 RRSGDLDALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEA 114
Query: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSI 124
CA IL++ GA+ NL D+YGNTALHYAVYSE S+ KLLSHGA IE +K + TPLL +I
Sbjct: 115 CAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAI 174
Query: 125 TKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVT 184
+ E++VEFLL K A+++AV++ + +ALMLAV + S IV +LL+QN+DVFA D+CG
Sbjct: 175 ICKKEKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRD 234
Query: 185 AEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVE 244
AE YA++ I +QI+E+ +K+ K E + G+ DE +A S+
Sbjct: 235 AEDYAISHHLTKIQQQILEHKKKILKK------EKSDVGSSDE----------SAVSIFH 278
Query: 245 KTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPRE 304
+ ++ P + D + + P++ + + G+S + + E P
Sbjct: 279 ELRVDSLPASD-DKDLNVATKQCVPEKVSEPLPGSSHE-------KGNRIVNGQGEGP-- 328
Query: 305 ITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWE 364
PAK S K + + K A ++K SE + + R E
Sbjct: 329 ---PAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASE------EEQERHERSE 379
Query: 365 KKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQR---------FPSE 415
KK+ VK G N T EK + C + S+ QR FP +
Sbjct: 380 KKQPQVKEG-------NNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKK 432
Query: 416 SKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQN 475
K+E D C + E + + +Y+K NR EE +K +K +E +
Sbjct: 433 LKEEHDR---CTLKQENEEKTNVNM-----LYKK----NR--EELERKEKQYKKEVEAKQ 478
Query: 476 SVPN-KAFELKNEQTLRADP 494
P ++ E+K+ +T R P
Sbjct: 479 LEPTVQSLEMKS-KTARNTP 497
Score = 55.8 bits (133), Expect = 3e-07
Identities = 120/595 (20%), Positives = 226/595 (37%), Gaps = 62/595 (10%)
Query: 377 RVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFESSA 436
++ +K K+L+K +S + + + S + ++ R S ++ + + + E
Sbjct: 250 QILEHKKKILKKEKSDV---GSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE--- 303
Query: 437 KIQVCIPESIYQKVMEI-NREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPM 495
K+ +P S ++K I N + E PP K + KP+ E+++ A + KN QTLRA+
Sbjct: 304 KVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQA 363
Query: 496 FPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKAT 555
P S+++ +E SE Q V T++ E +++ + +S + + T
Sbjct: 364 LPVASEEE--QERHERSEK-----KQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLT 416
Query: 556 CGMKV------SIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTL 609
K+ P K E D T K E K + L KN + L
Sbjct: 417 QQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------NMLYKKNREEL 463
Query: 610 RADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDG 669
E K+K Y++ + + L TV ++ A + D N + G
Sbjct: 464 --------ERKEKQYKKEV-EAKQLEPTVQSLEMKSKTARNTPNWDFHNHE-----EMKG 509
Query: 670 LLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLR 729
L+ NC +K I E+ M+ E K ++ + K ++L E
Sbjct: 510 LMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569
Query: 730 ADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGF 789
E E + ++E L E S+K + ++Q + K ES +
Sbjct: 570 TAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERN 629
Query: 790 LKAPCRMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLRA 849
LK + + + KAE + F + + AL+ K +T +
Sbjct: 630 LKLALERTRDVSVQVEMSSAISKVKAE-----NEFLTEQLSETQIKFNALKDKFRKTRDS 684
Query: 850 --DQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEM--DKISGKLEDSTSL 905
+ E+ Q + + ++ ++E + V +T + ++I ++ L
Sbjct: 685 LRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWL 744
Query: 906 SKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCV---LKKKLSEAKEIKSQL 957
+ LD VH E +E+ + + G +E KK + KK ++E +K L
Sbjct: 745 VQQLDDVHQKEDHKEIVTN---IQRGFIESGKKDLVLEEKSKKLMNECDHLKESL 796
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 281 bits (719), Expect = 3e-75
Identities = 185/525 (35%), Positives = 288/525 (54%), Gaps = 51/525 (9%)
Query: 817 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFP--SESKQKKVEENSWDSESLRE 874
PP K + +P+ E++ A++ KN QTLRA+Q P SE +Q++ E R
Sbjct: 328 PPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQQRHE---------RS 378
Query: 875 TVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKME 934
Q V T++ E ++S + DSTS + G++
Sbjct: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAA----------------------AGRLT 416
Query: 935 QMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIRE 994
Q +K K Q +K+K E + C TL QE E++ N ++L +K RE
Sbjct: 417 QQRKI----------GKTYPQQFP-KKLKEEHDRC----TLKQENEEKTNVNMLYKKNRE 461
Query: 995 ELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKE 1054
EL R E+Q++KE+E KQ LE ++ +++ K+ + N H HE L+ ENC+LK +
Sbjct: 462 ELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKAD 520
Query: 1055 IAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKV 1114
IA+L+ EI T+K+ EKENKY +DIKI+KE NA L+ +KL EE +T+ A +Y +L
Sbjct: 521 IAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELND 580
Query: 1115 LIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDA 1173
L AENT L ++L KEK+ K+ LEA+IES+ RLA+A+ H + V + ++ + A D
Sbjct: 581 LKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDV 640
Query: 1174 CLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQR 1233
+Q +M+ +S NE L + LSE Q K +LK D+LR+ +L E Q +
Sbjct: 641 SVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLS 700
Query: 1234 ETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSK 1293
+TQ Q +E + MYQN + VN T + +++++ LQ +N WL QQL H+K D+K
Sbjct: 701 QTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEI 760
Query: 1294 IT-IDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAE 1337
+T I F+E + +L+EK++++ N +HLK ++QYE+EK E
Sbjct: 761 VTNIQRGFIESGKKDFVLEEKSKKLMNECDHLKESLFQYEREKTE 805
Score = 224 bits (572), Expect = 3e-58
Identities = 171/500 (34%), Positives = 257/500 (51%), Gaps = 67/500 (13%)
Query: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
+++ L+ D Q RTALH AC +GH +VVT LV+RKCQ+DV D E+RTPL++A+ C +EA
Sbjct: 55 RRSGELDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEA 114
Query: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSI 124
CA IL++ GA+ NL D+YGNTALHYAVYSE S+ KLLSHGA IE +K + TPLL +I
Sbjct: 115 CAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAI 174
Query: 125 TKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVT 184
+ E++VEFLL K A+++AV++ + +ALMLAV + S IV +LL+QN+DVFA D+CG
Sbjct: 175 ICKKEKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRD 234
Query: 185 AEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVE 244
AE YA++ I +QI+E+ +K+ K E + G+ DE +A S+
Sbjct: 235 AEDYAISHHLTKIQQQILEHKKKILKK------EKSDVGSSDE----------SAVSIFH 278
Query: 245 KTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPRE 304
+ ++ P + D + + P++ + + G+S + + E P
Sbjct: 279 ELRVDSLPASD-DKDLNVATKQCVPEKVSEPLPGSSHE-------KGNRIVNGQGEGP-- 328
Query: 305 ITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWE 364
PAK S K + + K A ++K SE + + R E
Sbjct: 329 ---PAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASE------EEQQRHERSE 379
Query: 365 KKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQR---------FPSE 415
KK+ VK G N T EK + C + S+ QR FP +
Sbjct: 380 KKQPQVKEG-------NNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKK 432
Query: 416 SKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPKKPSAFKPAIEMQN 475
K+E D C + E + + +Y+K NR EE +K +K +E +
Sbjct: 433 LKEEHDR---CTLKQENEEKTNVNM-----LYKK----NR--EELERKEKQYKKEVEAKQ 478
Query: 476 SVPN-KAFELKNEQTLRADP 494
P ++ E+K+ +T R P
Sbjct: 479 LEPTVQSLEMKS-KTARNTP 497
Score = 60.1 bits (144), Expect = 1e-08
Identities = 122/621 (19%), Positives = 244/621 (39%), Gaps = 74/621 (11%)
Query: 377 RVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFESSA 436
++ +K K+L+K +S + + + S + ++ R S ++ + + + E
Sbjct: 250 QILEHKKKILKKEKSDV---GSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE--- 303
Query: 437 KIQVCIPESIYQKVMEI-NREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPM 495
K+ +P S ++K I N + E PP K + KP+ E+++ A + KN QTLRA+
Sbjct: 304 KVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQA 363
Query: 496 FPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKAT 555
P S+++ + + Q V T++ E +++ + +S + + T
Sbjct: 364 LPVASEEEQQRHERSEKK-------QPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLT 416
Query: 556 CGMKV------SIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTL 609
K+ P K E D T K E K + L KN + L
Sbjct: 417 QQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------NMLYKKNREEL 463
Query: 610 RADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDG 669
E K+K Y++ + + L TV ++ A + D N + G
Sbjct: 464 --------ERKEKQYKKEV-EAKQLEPTVQSLEMKSKTARNTPNWDFHNHE-----EMKG 509
Query: 670 LLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLR 729
L+ NC +K I E+ M+ E K ++ + K ++L E
Sbjct: 510 LMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569
Query: 730 ADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGF 789
E E + ++E L E S+K + ++Q + K ES +
Sbjct: 570 TAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERN 629
Query: 790 LKAPCR------MKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI-----EMQKSVPNKA 838
LK ++V + + ++ D F E + A+ + + S+ K+
Sbjct: 630 LKLALERTQDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKS 689
Query: 839 LELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDKISGK 898
L L+ Q + + ++ + ++++E ++E+ + K CV ++I
Sbjct: 690 LALETVQ----NNLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVE--------ERICHL 737
Query: 899 LEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLE 958
++ L + LD VH E +E+ + + G +E KK F VL++K + L+
Sbjct: 738 QRENAWLVQQLDDVHQKEDHKEIVTN---IQRGFIESGKKDF-VLEEKSKKLMNECDHLK 793
Query: 959 NQKVKWEQELCSVRLTLNQEE 979
++E+E V +++ +++
Sbjct: 794 ESLFQYEREKTEVVVSIKEDK 814
>gi|239756223 PREDICTED: ankyrin repeat domain-containing protein
ENSP00000383090-like [Homo sapiens]
Length = 270
Score = 277 bits (708), Expect = 6e-74
Identities = 147/235 (62%), Positives = 165/235 (70%), Gaps = 46/235 (19%)
Query: 15 AQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILIDSGA 74
A ++TALHW C NGH EVVT LVDRKCQLD+LDGE+RTPLMKA QC +E CANILIDSGA
Sbjct: 82 AVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGA 141
Query: 75 DINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIVEF 134
D N+VDVYGNTA+HYA+Y E LSVVAKLLS GA IEV NKA TPLLL+I KRSEQIVEF
Sbjct: 142 DPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEF 201
Query: 135 LLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTCGF 194
LL KN NANAV+K+KC
Sbjct: 202 LLTKNTNANAVDKFKC-------------------------------------------- 217
Query: 195 HHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPDE 249
IH+Q++EY +K+SKN QN+NPEGTS GTPDEAAPL ERTPD AESLVE+TPDE
Sbjct: 218 --IHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 270
Score = 35.4 bits (80), Expect = 0.37
Identities = 20/72 (27%), Positives = 33/72 (45%)
Query: 11 NIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILI 70
NI D TA+H+A + VV L+ ++V + TPL+ A++ E L+
Sbjct: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
Query: 71 DSGADINLVDVY 82
+ N VD +
Sbjct: 204 TKNTNANAVDKF 215
>gi|239745040 PREDICTED: ankyrin repeat domain-containing protein
ENSP00000383090-like [Homo sapiens]
Length = 270
Score = 277 bits (708), Expect = 6e-74
Identities = 147/235 (62%), Positives = 165/235 (70%), Gaps = 46/235 (19%)
Query: 15 AQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILIDSGA 74
A ++TALHW C NGH EVVT LVDRKCQLD+LDGE+RTPLMKA QC +E CANILIDSGA
Sbjct: 82 AVEKTALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGA 141
Query: 75 DINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIVEF 134
D N+VDVYGNTA+HYA+Y E LSVVAKLLS GA IEV NKA TPLLL+I KRSEQIVEF
Sbjct: 142 DPNIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEF 201
Query: 135 LLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTCGF 194
LL KN NANAV+K+KC
Sbjct: 202 LLTKNTNANAVDKFKC-------------------------------------------- 217
Query: 195 HHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPDE 249
IH+Q++EY +K+SKN QN+NPEGTS GTPDEAAPL ERTPD AESLVE+TPDE
Sbjct: 218 --IHQQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 270
Score = 35.4 bits (80), Expect = 0.37
Identities = 20/72 (27%), Positives = 33/72 (45%)
Query: 11 NIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILI 70
NI D TA+H+A + VV L+ ++V + TPL+ A++ E L+
Sbjct: 144 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 203
Query: 71 DSGADINLVDVY 82
+ N VD +
Sbjct: 204 TKNTNANAVDKF 215
>gi|169209369 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383090 [Homo sapiens]
Length = 193
Score = 275 bits (703), Expect = 2e-73
Identities = 146/231 (63%), Positives = 162/231 (70%), Gaps = 46/231 (19%)
Query: 19 TALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILIDSGADINL 78
TALHW C NGH EVVT LVDRKCQLD+LDGE+RTPLMKA QC +E CANILIDSGAD N+
Sbjct: 9 TALHWVCANGHAEVVTPLVDRKCQLDILDGENRTPLMKAAQCQREVCANILIDSGADPNI 68
Query: 79 VDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIVEFLLIK 138
VDVYGNTA+HYA+Y E LSVVAKLLS GA IEV NKA TPLLL+I KRSEQIVEFLL K
Sbjct: 69 VDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLLTK 128
Query: 139 NANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTCGFHHIH 198
N NANAV+K+KC IH
Sbjct: 129 NTNANAVDKFKC----------------------------------------------IH 142
Query: 199 EQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPDE 249
+Q++EY +K+SKN QN+NPEGTS GTPDEAAPL ERTPD AESLVE+TPDE
Sbjct: 143 QQLLEYKQKISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 193
Score = 35.4 bits (80), Expect = 0.37
Identities = 20/72 (27%), Positives = 33/72 (45%)
Query: 11 NIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILI 70
NI D TA+H+A + VV L+ ++V + TPL+ A++ E L+
Sbjct: 67 NIVDVYGNTAVHYALYGENLSVVAKLLSCGADIEVKNKAGHTPLLLAIRKRSEQIVEFLL 126
Query: 71 DSGADINLVDVY 82
+ N VD +
Sbjct: 127 TKNTNANAVDKF 138
>gi|169194585 PREDICTED: similar to hCG1793014 [Homo sapiens]
Length = 366
Score = 256 bits (653), Expect = 1e-67
Identities = 130/177 (73%), Positives = 148/177 (83%)
Query: 19 TALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILIDSGADINL 78
TALH ACVN H EV+T L DRKC+LDV D E+RTPLMKALQC +EACANIL+DSG N+
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREACANILVDSGPSPNI 86
Query: 79 VDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIVEFLLIK 138
VDVYGN ALHYAVYSE LSVVAKLLS GA IEV NKA LTPLLL ITKRSE+IVEFL+ K
Sbjct: 87 VDVYGNMALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLVTK 146
Query: 139 NANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTCGFH 195
NA+ANAV+K+KCTALMLAVCHGS E V +LLQQ++D+ A D+CG+TA YAV F+
Sbjct: 147 NASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASRFN 203
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/108 (29%), Positives = 46/108 (42%)
Query: 11 NIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILI 70
NI D ALH+A + + VV L+ R ++V + TPL+ + E L+
Sbjct: 85 NIVDVYGNMALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLV 144
Query: 71 DSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLT 118
A N VD + TAL AV L V+ LL I + +T
Sbjct: 145 TKNASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMT 192
>gi|169201955 PREDICTED: similar to hCG1793014 [Homo sapiens]
Length = 366
Score = 256 bits (653), Expect = 1e-67
Identities = 130/177 (73%), Positives = 148/177 (83%)
Query: 19 TALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILIDSGADINL 78
TALH ACVN H EV+T L DRKC+LDV D E+RTPLMKALQC +EACANIL+DSG N+
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREACANILVDSGPSPNI 86
Query: 79 VDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIVEFLLIK 138
VDVYGN ALHYAVYSE LSVVAKLLS GA IEV NKA LTPLLL ITKRSE+IVEFL+ K
Sbjct: 87 VDVYGNMALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLVTK 146
Query: 139 NANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTCGFH 195
NA+ANAV+K+KCTALMLAVCHGS E V +LLQQ++D+ A D+CG+TA YAV F+
Sbjct: 147 NASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASRFN 203
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/108 (29%), Positives = 46/108 (42%)
Query: 11 NIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILI 70
NI D ALH+A + + VV L+ R ++V + TPL+ + E L+
Sbjct: 85 NIVDVYGNMALHYAVYSENLSVVAKLLSRGADIEVKNKACLTPLLLVITKRSEEIVEFLV 144
Query: 71 DSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLT 118
A N VD + TAL AV L V+ LL I + +T
Sbjct: 145 TKNASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMT 192
>gi|169192125 PREDICTED: similar to UNCoordinated family member
(unc-44) [Homo sapiens]
Length = 393
Score = 250 bits (639), Expect = 6e-66
Identities = 128/177 (72%), Positives = 147/177 (83%)
Query: 19 TALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILIDSGADINL 78
TALH ACVN H EV+T L DRKC+LDV D E+RTPLMKALQC +EA ANIL+DSG N+
Sbjct: 27 TALHGACVNSHVEVITLLADRKCRLDVRDSENRTPLMKALQCWREAYANILVDSGPSPNI 86
Query: 79 VDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIVEFLLIK 138
VDVYGN ALHYAVYSE LSVVAKLLS GA I+V NKA LTPLLL ITKRSE+IVEFL+ K
Sbjct: 87 VDVYGNMALHYAVYSENLSVVAKLLSRGADIQVKNKACLTPLLLVITKRSEEIVEFLVTK 146
Query: 139 NANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTCGFH 195
NA+ANAV+K+KCTALMLAVCHGS E V +LLQQ++D+ A D+CG+TA YAV F+
Sbjct: 147 NASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMTAGGYAVASRFN 203
Score = 42.4 bits (98), Expect = 0.003
Identities = 32/108 (29%), Positives = 45/108 (41%)
Query: 11 NIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANILI 70
NI D ALH+A + + VV L+ R + V + TPL+ + E L+
Sbjct: 85 NIVDVYGNMALHYAVYSENLSVVAKLLSRGADIQVKNKACLTPLLLVITKRSEEIVEFLV 144
Query: 71 DSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLT 118
A N VD + TAL AV L V+ LL I + +T
Sbjct: 145 TKNASANAVDKFKCTALMLAVCHGSLERVSILLQQDIDICAEDMCGMT 192
>gi|153791352 prostate, ovary, testis expressed protein on
chromosome 2 [Homo sapiens]
Length = 1075
Score = 219 bits (558), Expect = 1e-56
Identities = 151/443 (34%), Positives = 235/443 (53%), Gaps = 31/443 (6%)
Query: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANI 68
++N QD QKRTALH A NG+ EVV L+DR+CQL+VLD + RT L+KA+QC ++ CA +
Sbjct: 165 DVNKQDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALM 224
Query: 69 LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRS 128
L++ G D N+ D YGNT LHYA+Y+E + LL +GA IE NK LTPLLL + ++
Sbjct: 225 LLEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQK 284
Query: 129 EQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHY 188
+Q+V+FL+ K AN NA+++Y TAL+LAVC GS+ IV +LL+QN+DV + D+ G TA Y
Sbjct: 285 QQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREY 344
Query: 189 AVTCGFHHIHEQIMEYIRK--LSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKT 246
AV+ H I + + +Y K L + +N+NPE T +E ++R + S EK
Sbjct: 345 AVSSHHHVICQLLSDYKEKQMLKISSENSNPEQDLKLTSEEE---SQRFKGSENSQPEKM 401
Query: 247 PDEAAPLVERTPD-TAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPREI 305
E P + + D E ++K L+E ++ + +G Q TP
Sbjct: 402 SQE--PEINKDGDREVEEEMKKHESNNVGLLENLTNGVTA-GNGDNGLIPQRKSRTPENQ 458
Query: 306 TSPAKETSEKF-------TWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRP 358
P E+ E + K P+ + + + +++ ++E S++ + G+P
Sbjct: 459 QFPDNESEEYHRICELLSDYKEKQMPKYSS--ENSNPEQDLKLTSEEESQRLKGSENGQP 516
Query: 359 RKIAWEKKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTK--ESSTKASANDQRFP--- 413
K + E + K G + ++K RS + P +T + +D P
Sbjct: 517 EKRSQEPEIN--KDGDRELENFMAIEEMKKHRSTHVGFPENLTNGATAGNGDDGLIPPRK 574
Query: 414 ---SESKQ---EEDEEYSCDSRS 430
ES+Q E+EEY D ++
Sbjct: 575 SRTPESQQFPDTENEEYHSDEQN 597
Score = 69.3 bits (168), Expect = 2e-11
Identities = 41/120 (34%), Positives = 72/120 (60%), Gaps = 1/120 (0%)
Query: 980 EKRRNADILNEKIR-EELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTH 1038
E ++ D NE+ +E ++Q +E ++ L ++ +++ VE +++S +
Sbjct: 579 ESQQFPDTENEEYHSDEQNDTQKQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSC 638
Query: 1039 ENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKE 1098
+ E +LHEN L++EIAML+LE+ T+KHQ Q +E KY EDI+ +K++N L L+L E
Sbjct: 639 KKEKDILHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKRNDNLLKALQLNE 698
Score = 35.8 bits (81), Expect = 0.28
Identities = 107/577 (18%), Positives = 209/577 (36%), Gaps = 121/577 (20%)
Query: 135 LLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTCGF 194
+++++ + N +K K TAL LA +G+SE+V +LL + + D TA AV C
Sbjct: 159 VMLRDTDVNKQDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQE 218
Query: 195 HHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAP-------------LAERTPDTAES 241
++E+ GT PDE +A+
Sbjct: 219 DECALMLLEH--------------GTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGAD 264
Query: 242 LVEKTPDEAAPLV----ERTPDTAESLVEKTPDEAA-----------SLVEGTSDKIQ-C 285
+ K PL+ E+ + L++K + A ++ G++ +
Sbjct: 265 IESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVSLL 324
Query: 286 LEKATSGKFEQSAEETPRE--ITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPA 343
LE+ + + +T RE ++S + + + + KI+ E + +++ +
Sbjct: 325 LEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSE-NSNPEQDLKLTS 383
Query: 344 KETSEKFTWAAKGRPRKIAWE---------------KKETPVKTGCVARVTSNKTKVLEK 388
+E S++F + +P K++ E KK G + +T+ T
Sbjct: 384 EEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGVT----A 439
Query: 389 GRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFESSAKIQVCIPESIYQ 448
G P ++S T +Q+FP +E Y
Sbjct: 440 GNGDNGLIPQRKSRT---PENQQFPDNESEE---------------------------YH 469
Query: 449 KVMEINREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNE---QTLRADPMFPPESKQKDY 505
++ E+ + +E P +NS P + +L +E Q L+ PE + ++
Sbjct: 470 RICELLSDYKEKQ------MPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEP 523
Query: 506 EENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKATCGMKVSIPTK 565
E N L ++ +++ ++TH + + DGL IP +
Sbjct: 524 EINKDGDRELENFMAIEEMKKHRSTHVGFPENLTNGATAGNGDDGL----------IPPR 573
Query: 566 ALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTLRADEILPSESKQKDYE 625
+ Q F P + + ++ Q + E +N L DEIL E KQ +
Sbjct: 574 KSRTPESQQF---PDTENEEYH--SDEQNDTQKQFCEEQNTGILH-DEILIHEEKQIEVV 627
Query: 626 ENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLE 662
E ++E +KD+ + ++EI + +L+
Sbjct: 628 E-KMNSELSLSCKKEKDILHENSTLREEIAMLRLELD 663
Score = 32.0 bits (71), Expect = 4.1
Identities = 20/67 (29%), Positives = 29/67 (43%)
Query: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
KK NLN D RTAL A G +V+ L+++ + D +T A+ H
Sbjct: 293 KKKANLNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHV 352
Query: 65 CANILID 71
+L D
Sbjct: 353 ICQLLSD 359
>gi|239756067 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383069 [Homo sapiens]
Length = 157
Score = 218 bits (554), Expect = 4e-56
Identities = 113/148 (76%), Positives = 127/148 (85%), Gaps = 2/148 (1%)
Query: 4 RKKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQE 63
+K T++ NI+DA+KRTALHWAC NGH EVVT LVDRKCQLDVLDGE+ TPLMKA+QC +E
Sbjct: 3 KKTTMDPNIRDAKKRTALHWACANGHAEVVTLLVDRKCQLDVLDGENGTPLMKAVQCQRE 62
Query: 64 ACANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLS 123
CANILIDSGAD N+VDVY NTA+HYAVY E LSVVAKLLS GA I+V NKA TPLLL+
Sbjct: 63 VCANILIDSGADPNIVDVYVNTAVHYAVYGENLSVVAKLLSCGADIKVKNKAGHTPLLLA 122
Query: 124 ITKRSEQIVEFLLIKNANANA--VNKYK 149
I KRSEQIVEFLL KNANANA V+K+K
Sbjct: 123 IRKRSEQIVEFLLTKNANANANSVDKFK 150
Score = 47.4 bits (111), Expect = 9e-05
Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 6/137 (4%)
Query: 75 DINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRSEQIVEF 134
D N+ D TALH+A + VV L+ ++V + + TPL+ ++ + E
Sbjct: 8 DPNIRDAKKRTALHWACANGHAEVVTLLVDRKCQLDVLDGENGTPLMKAVQCQREVCANI 67
Query: 135 LLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHYAVTCGF 194
L+ A+ N V+ Y TA+ AV + +V LL D+ + G H +
Sbjct: 68 LIDSGADPNIVDVYVNTAVHYAVYGENLSVVAKLLSCGADIKVKNKAG----HTPLLLAI 123
Query: 195 HHIHEQIMEYIRKLSKN 211
EQI+E++ L+KN
Sbjct: 124 RKRSEQIVEFL--LTKN 138
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 215 bits (548), Expect = 2e-55
Identities = 116/266 (43%), Positives = 161/266 (60%)
Query: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANI 68
+L+++D + RT LH AC +G +VVT L+DRKCQ+++ D +RTPLMKA+ C +EACA I
Sbjct: 159 DLDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAII 218
Query: 69 LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRS 128
L+ GA+ N+ D+YGNTALHYAVY+E S+ +LLSH A IE NK TPLL +I R
Sbjct: 219 LLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRR 278
Query: 129 EQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHY 188
+ +VEFLL AN +AV+ +K TAL+LAV H S IV +LLQQN+ + + D+ G TAE Y
Sbjct: 279 QHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDY 338
Query: 189 AVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPD 248
A C I +QI+E+ K+ KNH + + T+A P+ +R K
Sbjct: 339 AFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEH 398
Query: 249 EAAPLVERTPDTAESLVEKTPDEAAS 274
E + E K P ++ S
Sbjct: 399 NLKVASEEKQERLERSENKQPQDSQS 424
Score = 206 bits (524), Expect = 1e-52
Identities = 134/367 (36%), Positives = 213/367 (58%), Gaps = 10/367 (2%)
Query: 976 NQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVS 1035
NQE + ++ K R++L + +E + E +K E+ + L+ E+ Q S
Sbjct: 367 NQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEE----KQERLERSENKQPQDS 422
Query: 1036 HTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLK 1095
++ + + N MLK++IAMLK E+ +K+ KE KY ++IK + E NA + +++
Sbjct: 423 QSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVR 482
Query: 1096 LKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHD 1154
L EE +TK+ +QYS QL L AEN L SKL KEK +KE LEAE+ES H LA+A+ +++
Sbjct: 483 LNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYN 542
Query: 1155 QIVTSRKSQEPAFHIAGDACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYA 1214
+I+ RK E A D M ++S NE+L + + +A+ K +LK L
Sbjct: 543 EIL-ERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 601
Query: 1215 GDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKN 1274
DALRE TL E Q D ++ Q ++KE + M+ N + ++ +Q S ++++ Q + +N
Sbjct: 602 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELEN 661
Query: 1275 MWLQQQLVHAHKKADNKSKITIDIH--FLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYE 1332
+ L++QL A K+ DNK +I I+IH LE + LL+E+N+E+ N N+LK ++ QYE
Sbjct: 662 LLLERQLEDARKEGDNK-EIVINIHRDCLENG-KEDLLEERNKELMNEYNYLKEKLLQYE 719
Query: 1333 KEKAETE 1339
KEKAE E
Sbjct: 720 KEKAERE 726
Score = 54.7 bits (130), Expect = 6e-07
Identities = 32/99 (32%), Positives = 51/99 (51%)
Query: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
K+ N NI+D TALH+A N + L+ ++ L+ E TPL+ A+ ++
Sbjct: 221 KRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQH 280
Query: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLL 103
L+ + A+I+ VD + TAL AV + S+V LL
Sbjct: 281 MVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLL 319
Score = 43.9 bits (102), Expect = 0.001
Identities = 197/1005 (19%), Positives = 379/1005 (37%), Gaps = 156/1005 (15%)
Query: 109 IEVHNKASLTPLLLSITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGML 168
++V +K T L L+ Q+V LL + N ++ T LM AV +L
Sbjct: 160 LDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIIL 219
Query: 169 LQQNVDVFAADICGVTAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEA 228
L++ + DI G TA HYAV + + +L +H N TP
Sbjct: 220 LKRGANPNIKDIYGNTALHYAV-------YNEGTSLAERLLSHHANIEALNKEGNTPLLF 272
Query: 229 APLAERTPDTAESLVEKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEK 288
A + R L + A +RT +L+ +S+V T Q +
Sbjct: 273 AINSRRQHMVEFLLKNQANIHAVDNFKRT-----ALILAVQHNLSSIV--TLLLQQNIHI 325
Query: 289 ATSGKFEQSAEETPREITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSE 348
++ F Q+AE+ F + ++I K + + + +ET+
Sbjct: 326 SSQDMFGQTAEDYA-------------FCCDLRSIQQQILEHKNKMLKNHLRNDNQETAA 372
Query: 349 KFTWAAKGRPRKIAWEKKETPVKTGCVARVTSN-KTKVLEKGRSKMIACPTKESSTKASA 407
K R ++ +K++ K +V S K + LE+ +K ++S +
Sbjct: 373 MKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ----PQDSQSYGKK 428
Query: 408 NDQRFPSESKQEE-----DEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPK 462
D+ F + + + +E Y+ + SL + IQ + + EIN E+ +
Sbjct: 429 KDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEI------KSITEINANFEKSVR 482
Query: 463 KPSAFKPAIEMQNSVPNKAFELKNEQTLRADPMFPPESKQKDYEENSWDS--ESLCETVS 520
Q S + +LK E R + E K+ E +S +L ++
Sbjct: 483 LNEEMITKKVAQYS--QQLNDLKAENA-RLNSKLEKEKHNKERLEAEVESLHSNLATAIN 539
Query: 521 QKDVCLPKATHQKEIDKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPP 580
+ + L + K+++ + + ++ + T G +S T EL Q KA
Sbjct: 540 EYNEILER----KDLELVLWRADDVSRHE-----TMGSNISQLTDKNELLTEQVHKARVK 590
Query: 581 GKPSAFEPATEMQKSVPNKALELKNEQT-LRADEILPSESKQKDYEENSWDTESLCETVS 639
+ E + ++ K L L++ Q L+ + E KQ + +++S+ + S
Sbjct: 591 FNTLKGK-LRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNS 649
Query: 640 QKDVCLPKAAHQKEIDKI--NGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAE 697
++ Q+E++ + +LE + K+G N + ++I LE +
Sbjct: 650 SEE-----RIRQRELENLLLERQLEDAR-KEG---DNKEIVINIHRDCLENGKEDLLEER 700
Query: 698 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCETV 757
E + + E K L+ + E+ R + + + D+ + SES E
Sbjct: 701 NKELMNEYNYLKE-------KLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGT 753
Query: 758 SQKDVCLPKA-THQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAE 816
S + L + T +K++ ++ + EE + K EL+ + + A+
Sbjct: 754 SHCHINLDETWTSKKKLFQVEIQPEEKHEEF--------------RKVFELISLLNYTAD 799
Query: 817 PPEKPS------------AFEPAIEMQKSVPNKALELK---NEQTLRADQMFPSESKQKK 861
K + E I M + N+ N L+ D +F KK
Sbjct: 800 QIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILF------KK 853
Query: 862 VEENSWDSESLRETVSQKDVCVPKATHQKEMDKIS-GKLEDSTSLSKILDTVHSCERARE 920
+++ D + +E VS K V + K + +S GK+++ CE+ E
Sbjct: 854 LKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEK------------CEKL-E 900
Query: 921 LQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEE 980
K E++ ++ +K V +L + +E KS+L+ + ++ ++L + L E E
Sbjct: 901 KDKKMLEEKVLNLKTHMEKDMV---ELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYE 957
Query: 981 KRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHEN 1040
K +L ++ + + L+ K+ L ++D+E K + T E
Sbjct: 958 K-------------QLEQLNKDNTASLKKKE-----LTLKDVECKFSKMKTAYEDVTTEL 999
Query: 1041 ENY------LLHENCMLKKEIAMLKLEIATLKHQ-YQEKEN-KYF 1077
E Y L N + ++I +IA + + + EKE +YF
Sbjct: 1000 EEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYF 1044
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 215 bits (548), Expect = 2e-55
Identities = 116/266 (43%), Positives = 161/266 (60%)
Query: 9 NLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEACANI 68
+L+++D + RT LH AC +G +VVT L+DRKCQ+++ D +RTPLMKA+ C +EACA I
Sbjct: 188 DLDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAII 247
Query: 69 LIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSITKRS 128
L+ GA+ N+ D+YGNTALHYAVY+E S+ +LLSH A IE NK TPLL +I R
Sbjct: 248 LLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRR 307
Query: 129 EQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVTAEHY 188
+ +VEFLL AN +AV+ +K TAL+LAV H S IV +LLQQN+ + + D+ G TAE Y
Sbjct: 308 QHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDY 367
Query: 189 AVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPD 248
A C I +QI+E+ K+ KNH + + T+A P+ +R K
Sbjct: 368 AFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEH 427
Query: 249 EAAPLVERTPDTAESLVEKTPDEAAS 274
E + E K P ++ S
Sbjct: 428 NLKVASEEKQERLERSENKQPQDSQS 453
Score = 206 bits (524), Expect = 1e-52
Identities = 134/367 (36%), Positives = 213/367 (58%), Gaps = 10/367 (2%)
Query: 976 NQEEEKRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVS 1035
NQE + ++ K R++L + +E + E +K E+ + L+ E+ Q S
Sbjct: 396 NQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEE----KQERLERSENKQPQDS 451
Query: 1036 HTHENENYLLHENCMLKKEIAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLK 1095
++ + + N MLK++IAMLK E+ +K+ KE KY ++IK + E NA + +++
Sbjct: 452 QSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVR 511
Query: 1096 LKEESLTKRASQYSGQLKVLIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHD 1154
L EE +TK+ +QYS QL L AEN L SKL KEK +KE LEAE+ES H LA+A+ +++
Sbjct: 512 LNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYN 571
Query: 1155 QIVTSRKSQEPAFHIAGDACLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYA 1214
+I+ RK E A D M ++S NE+L + + +A+ K +LK L
Sbjct: 572 EIL-ERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 630
Query: 1215 GDALRENTLVSEHAQRDQRETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKN 1274
DALRE TL E Q D ++ Q ++KE + M+ N + ++ +Q S ++++ Q + +N
Sbjct: 631 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELEN 690
Query: 1275 MWLQQQLVHAHKKADNKSKITIDIH--FLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYE 1332
+ L++QL A K+ DNK +I I+IH LE + LL+E+N+E+ N N+LK ++ QYE
Sbjct: 691 LLLERQLEDARKEGDNK-EIVINIHRDCLENG-KEDLLEERNKELMNEYNYLKEKLLQYE 748
Query: 1333 KEKAETE 1339
KEKAE E
Sbjct: 749 KEKAERE 755
Score = 54.7 bits (130), Expect = 6e-07
Identities = 32/99 (32%), Positives = 51/99 (51%)
Query: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64
K+ N NI+D TALH+A N + L+ ++ L+ E TPL+ A+ ++
Sbjct: 250 KRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQH 309
Query: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLL 103
L+ + A+I+ VD + TAL AV + S+V LL
Sbjct: 310 MVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLL 348
Score = 43.9 bits (102), Expect = 0.001
Identities = 197/1005 (19%), Positives = 379/1005 (37%), Gaps = 156/1005 (15%)
Query: 109 IEVHNKASLTPLLLSITKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGML 168
++V +K T L L+ Q+V LL + N ++ T LM AV +L
Sbjct: 189 LDVRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIIL 248
Query: 169 LQQNVDVFAADICGVTAEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEA 228
L++ + DI G TA HYAV + + +L +H N TP
Sbjct: 249 LKRGANPNIKDIYGNTALHYAV-------YNEGTSLAERLLSHHANIEALNKEGNTPLLF 301
Query: 229 APLAERTPDTAESLVEKTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEK 288
A + R L + A +RT +L+ +S+V T Q +
Sbjct: 302 AINSRRQHMVEFLLKNQANIHAVDNFKRT-----ALILAVQHNLSSIV--TLLLQQNIHI 354
Query: 289 ATSGKFEQSAEETPREITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSE 348
++ F Q+AE+ F + ++I K + + + +ET+
Sbjct: 355 SSQDMFGQTAEDYA-------------FCCDLRSIQQQILEHKNKMLKNHLRNDNQETAA 401
Query: 349 KFTWAAKGRPRKIAWEKKETPVKTGCVARVTSN-KTKVLEKGRSKMIACPTKESSTKASA 407
K R ++ +K++ K +V S K + LE+ +K ++S +
Sbjct: 402 MKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQ----PQDSQSYGKK 457
Query: 408 NDQRFPSESKQEE-----DEEYSCDSRSLFESSAKIQVCIPESIYQKVMEINREVEEPPK 462
D+ F + + + +E Y+ + SL + IQ + + EIN E+ +
Sbjct: 458 KDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEI------KSITEINANFEKSVR 511
Query: 463 KPSAFKPAIEMQNSVPNKAFELKNEQTLRADPMFPPESKQKDYEENSWDS--ESLCETVS 520
Q S + +LK E R + E K+ E +S +L ++
Sbjct: 512 LNEEMITKKVAQYS--QQLNDLKAENA-RLNSKLEKEKHNKERLEAEVESLHSNLATAIN 568
Query: 521 QKDVCLPKATHQKEIDKINGKLEESPNKDGLLKATCGMKVSIPTKALELKDMQTFKAEPP 580
+ + L + K+++ + + ++ + T G +S T EL Q KA
Sbjct: 569 EYNEILER----KDLELVLWRADDVSRHE-----TMGSNISQLTDKNELLTEQVHKARVK 619
Query: 581 GKPSAFEPATEMQKSVPNKALELKNEQT-LRADEILPSESKQKDYEENSWDTESLCETVS 639
+ E + ++ K L L++ Q L+ + E KQ + +++S+ + S
Sbjct: 620 FNTLKGK-LRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNS 678
Query: 640 QKDVCLPKAAHQKEIDKI--NGKLEGSPVKDGLLKANCGMKVSIPTKALELMDMQTFKAE 697
++ Q+E++ + +LE + K+G N + ++I LE +
Sbjct: 679 SEE-----RIRQRELENLLLERQLEDAR-KEG---DNKEIVINIHRDCLENGKEDLLEER 729
Query: 698 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADEILPSESKQKDYEESSWDSESLCETV 757
E + + E K L+ + E+ R + + + D+ + SES E
Sbjct: 730 NKELMNEYNYLKE-------KLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGT 782
Query: 758 SQKDVCLPKA-THQKEIDKINGKLEESPDNDGFLKAPCRMKVSIPTKALELMDMQTFKAE 816
S + L + T +K++ ++ + EE + K EL+ + + A+
Sbjct: 783 SHCHINLDETWTSKKKLFQVEIQPEEKHEEF--------------RKVFELISLLNYTAD 828
Query: 817 PPEKPS------------AFEPAIEMQKSVPNKALELK---NEQTLRADQMFPSESKQKK 861
K + E I M + N+ N L+ D +F KK
Sbjct: 829 QIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILF------KK 882
Query: 862 VEENSWDSESLRETVSQKDVCVPKATHQKEMDKIS-GKLEDSTSLSKILDTVHSCERARE 920
+++ D + +E VS K V + K + +S GK+++ CE+ E
Sbjct: 883 LKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEK------------CEKL-E 929
Query: 921 LQKDHCEQRTGKMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEE 980
K E++ ++ +K V +L + +E KS+L+ + ++ ++L + L E E
Sbjct: 930 KDKKMLEEKVLNLKTHMEKDMV---ELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYE 986
Query: 981 KRRNADILNEKIREELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHEN 1040
K +L ++ + + L+ K+ L ++D+E K + T E
Sbjct: 987 K-------------QLEQLNKDNTASLKKKE-----LTLKDVECKFSKMKTAYEDVTTEL 1028
Query: 1041 ENY------LLHENCMLKKEIAMLKLEIATLKHQ-YQEKEN-KYF 1077
E Y L N + ++I +IA + + + EKE +YF
Sbjct: 1029 EEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYF 1073
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,641,941
Number of Sequences: 37866
Number of extensions: 2411810
Number of successful extensions: 19264
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 480
Number of HSP's successfully gapped in prelim test: 1034
Number of HSP's that attempted gapping in prelim test: 9320
Number of HSP's gapped (non-prelim): 6008
length of query: 1341
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1227
effective length of database: 13,930,794
effective search space: 17093084238
effective search space used: 17093084238
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.