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Search of human proteins with 115430259
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115430259 solute carrier family 39 (zinc transporter),
member 4 isoform 1 [Homo sapiens]
(622 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115430259 solute carrier family 39 (zinc transporter), member... 1250 0.0
gi|115430255 solute carrier family 39 (zinc transporter), member... 1170 0.0
gi|223633939 solute carrier family 39 (zinc transporter), member... 286 5e-77
gi|223633937 solute carrier family 39 (zinc transporter), member... 271 2e-72
gi|190358541 solute carrier family 39 (zinc transporter), member... 204 2e-52
gi|206597541 solute carrier family 39 (metal ion transporter), m... 201 1e-51
gi|206597539 solute carrier family 39 (metal ion transporter), m... 201 1e-51
gi|205830424 solute carrier family 39 (zinc transporter), member... 197 2e-50
gi|190360568 solute carrier family 39 (zinc transporter), member... 197 2e-50
gi|24586665 solute carrier family 39 (zinc transporter), member ... 186 4e-47
gi|205830403 solute carrier family 39 (zinc transporter), member... 186 4e-47
gi|205830407 solute carrier family 39 (zinc transporter), member... 184 3e-46
gi|205830426 solute carrier family 39 (zinc transporter), member... 176 6e-44
gi|205830405 solute carrier family 39 (zinc transporter), member... 170 3e-42
gi|187936949 solute carrier family 39 (zinc transporter), member... 161 2e-39
gi|55741750 solute carrier family 39 (zinc transporter), member ... 161 2e-39
gi|153252201 solute carrier family 39 (zinc transporter), member... 154 2e-37
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 146 5e-35
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 146 5e-35
gi|153252214 solute carrier family 39 (zinc transporter), member... 130 3e-30
gi|40255101 solute carrier family 39 (zinc transporter), member ... 116 5e-26
gi|190014617 solute carrier family 39 (zinc transporter), member... 115 9e-26
gi|40254928 solute carrier family 39 (zinc transporter), member ... 51 3e-06
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 50 6e-06
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 50 6e-06
gi|156415986 solute carrier family 39 (zinc transporter), member... 45 2e-04
gi|124378039 SEC16 homolog A [Homo sapiens] 36 0.093
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 33 0.78
gi|239741896 PREDICTED: hypothetical protein XP_002342335 [Homo ... 33 0.78
gi|23308499 zinc finger protein 488 [Homo sapiens] 33 1.0
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 1250 bits (3235), Expect = 0.0
Identities = 622/622 (100%), Positives = 622/622 (100%)
Query: 1 MVDVVGLERETGPRGSPWPGLPLPSLVGPAPLLTCLCPQCLSVEDALGLGEPEGSGLPPG 60
MVDVVGLERETGPRGSPWPGLPLPSLVGPAPLLTCLCPQCLSVEDALGLGEPEGSGLPPG
Sbjct: 1 MVDVVGLERETGPRGSPWPGLPLPSLVGPAPLLTCLCPQCLSVEDALGLGEPEGSGLPPG 60
Query: 61 PVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALLESPKALTPGLSWLLQ 120
PVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALLESPKALTPGLSWLLQ
Sbjct: 61 PVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALLESPKALTPGLSWLLQ 120
Query: 121 RMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGGVLAALLDHVRSGSCFHALPSPQYF 180
RMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGGVLAALLDHVRSGSCFHALPSPQYF
Sbjct: 121 RMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGGVLAALLDHVRSGSCFHALPSPQYF 180
Query: 181 VDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDHSHRHRGASSRDPVPLISSSNSSSV 240
VDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDHSHRHRGASSRDPVPLISSSNSSSV
Sbjct: 181 VDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDHSHRHRGASSRDPVPLISSSNSSSV 240
Query: 241 WDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSE 300
WDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSE
Sbjct: 241 WDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSE 300
Query: 301 RYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVL 360
RYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVL
Sbjct: 301 RYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVL 360
Query: 361 GLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGG 420
GLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGG
Sbjct: 361 GLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGG 420
Query: 421 HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDA 480
HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDA
Sbjct: 421 HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDA 480
Query: 481 VHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLAS 540
VHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLAS
Sbjct: 481 VHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLAS 540
Query: 541 ALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHN 600
ALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHN
Sbjct: 541 ALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHN 600
Query: 601 VGLLGGWTVLLLLSLYEDDITF 622
VGLLGGWTVLLLLSLYEDDITF
Sbjct: 601 VGLLGGWTVLLLLSLYEDDITF 622
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 1170 bits (3026), Expect = 0.0
Identities = 584/586 (99%), Positives = 585/586 (99%)
Query: 37 CPQCLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWAS 96
C +CLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWAS
Sbjct: 62 CGKCLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWAS 121
Query: 97 HADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGG 156
HADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGG
Sbjct: 122 HADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGG 181
Query: 157 VLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDH 216
VLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDH
Sbjct: 182 VLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDH 241
Query: 217 SHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALL 276
SHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALL
Sbjct: 242 SHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALL 301
Query: 277 QQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYIL 336
QQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYIL
Sbjct: 302 QQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYIL 361
Query: 337 QTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFN 396
QTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFN
Sbjct: 362 QTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFN 421
Query: 397 LLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL 456
LLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL
Sbjct: 422 LLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL 481
Query: 457 LNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHE 516
LNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHE
Sbjct: 482 LNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHE 541
Query: 517 LGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVA 576
LGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVA
Sbjct: 542 LGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVA 601
Query: 577 LCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 622
LCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF
Sbjct: 602 LCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 647
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 286 bits (731), Expect = 5e-77
Identities = 171/471 (36%), Positives = 253/471 (53%), Gaps = 32/471 (6%)
Query: 174 LPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGV------GREAHSDHSHRHRGASSRD 227
LPSP YF +++F + + L+EL L+ L + H ++ +
Sbjct: 227 LPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQ 286
Query: 228 PVPLISSSNSSSV------WDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLS 281
SSS WD C SAR ++ + + ++ E + Q+SP ++QQ LS
Sbjct: 287 DYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLS 346
Query: 282 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 341
+C + + E+Y Y ++A L+ L ++ G L+ C ILQ F+
Sbjct: 347 CSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVG 406
Query: 342 LAVGALTGDAVLHLTPKVLGLHTHSEEGL-----SPQPTWRLLAMLAGLYAFFLFENLFN 396
LAVG L+GDA+LHL P+VLGLH S W+L+ ++ G++ FFL E F
Sbjct: 407 LAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFI 466
Query: 397 LLL-PRDPEDLE--DGPCGHSSH----SHGGHSHGVSLQLAPSELRQPKPPHEGSRADLV 449
LL+ P D + L +G GHS H S G + +L+ P+ D
Sbjct: 467 LLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPE--------DSQ 518
Query: 450 AEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVF 509
A E P R + LL MI +GD++HNFADGLA+GAAF+SS ++G+ T++A+
Sbjct: 519 AAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAIL 578
Query: 510 CHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVAT 569
CHE+PHE+GDFA LL +GLS++ A+L+N S+LTAF GLY+ L+V + WI V
Sbjct: 579 CHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTA 638
Query: 570 GLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDI 620
G+FLY++L +MLP M V+ RPW++FLL N GL+ GW LLLL++YE +I
Sbjct: 639 GMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNI 689
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 271 bits (692), Expect = 2e-72
Identities = 161/464 (34%), Positives = 242/464 (52%), Gaps = 55/464 (11%)
Query: 174 LPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGV------GREAHSDHSHRHRGASSRD 227
LPSP YF +++F + + L+EL L+ L + H ++ +
Sbjct: 227 LPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCIKNEKIHQFQRKQNNIITHDQ 286
Query: 228 PVPLISSSNSSSV------WDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLS 281
SSS WD C SAR ++ + + ++ E + Q+SP ++QQ LS
Sbjct: 287 DYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLSLISKEDFKQMSPGIIQQLLS 346
Query: 282 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 341
+C + + E+Y Y ++A L+ L ++ G L+ C ILQ F+
Sbjct: 347 CSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYRLILQLFVG 406
Query: 342 LAVGALTGDAVLHLTPKVLGLHTHSEEGL-----SPQPTWRLLAMLAGLYAFFLFENLFN 396
LAVG L+GDA+LHL P+VLGLH S W+L+ ++ G++ FFL E F
Sbjct: 407 LAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKLMGLIGGIHGFFLIEKCFI 466
Query: 397 LLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL 456
LL+ +P++ + P+ D A E P
Sbjct: 467 LLV------------------------------SPNDKKSPE--------DSQAAEMPIG 488
Query: 457 LNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHE 516
R + LL MI +GD++HNFADGLA+GAAF+SS ++G+ T++A+ CHE+PHE
Sbjct: 489 SMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHE 548
Query: 517 LGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVA 576
+GDFA LL +GLS++ A+L+N S+LTAF GLY+ L+V + WI V G+FLY++
Sbjct: 549 MGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQDWIFTVTAGMFLYLS 608
Query: 577 LCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDI 620
L +MLP M V+ RPW++FLL N GL+ GW LLLL++YE +I
Sbjct: 609 LVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIYEQNI 652
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 204 bits (520), Expect = 2e-52
Identities = 148/480 (30%), Positives = 233/480 (48%), Gaps = 72/480 (15%)
Query: 180 FVDFVFQQHSSEVPMTLAELSALMQRL--GVGREAHSDHSHRHRGASSRDPVPLISSSNS 237
F+ + ++ +TL +L AL+ L GVGR + H HR S+
Sbjct: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLST------------ 90
Query: 238 SSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLS 297
C S+ D+ A+ SEQ+ + + P +LQQ S ACTS+++ +++ +
Sbjct: 91 -------CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQT 143
Query: 298 QSER------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDA 351
+ R + +G L+ LI L ++ G+L+L CT + +L F++L++G L +A
Sbjct: 144 EEGRPSAVEVWGFGFLSVSLINLASLLGVLVLPCTE-KAFFSRVLTYFIALSIGTLLSNA 202
Query: 352 VLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPC 411
+ L P+ G + + +S + + G Y FF E + +LL + E
Sbjct: 203 LFQLIPEAFGFNPLEDYYVS-----KSAVVFGGFYLFFFTEKILKILLKQKNEH------ 251
Query: 412 GHSSHSHGG---------HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL-----L 457
H HSH GV +L +L P H S D A E L
Sbjct: 252 -HHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSL 310
Query: 458 NPEPRRLSP------------ELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATS 505
+ + + S ++ L +MITL D +HNF DGLA+GA+F S G++TS
Sbjct: 311 SVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTS 370
Query: 506 LAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWIL 565
+A+ C E PHELGDF LL+AG+S++QAL N SA + GL + G S S WI
Sbjct: 371 VAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG-SHFSANWIF 429
Query: 566 AVATGLFLYVALCDMLPAMLKV--RDPRPWLL---FLLHNVGLLGGWTVLLLLSLYEDDI 620
A+A G+FLY++L DM P M +V D R + F++ N+GLL G+T++++L++Y I
Sbjct: 430 ALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVLTMYSGQI 489
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 201 bits (512), Expect = 1e-51
Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 22/385 (5%)
Query: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRP-PVQDQLSQSERYL 303
CL+ ++ +GLS A +TP +A L PALL Q S C P P D LS L
Sbjct: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA---LL 214
Query: 304 YGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLH 363
+LA LL+ L + LLLL G R + +L +LAVG L GDA+LHL P
Sbjct: 215 QSALAVLLLSLPSPLSLLLLRLLGPR-LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGR 273
Query: 364 THSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHS- 422
GL + L++L GL+ F+ EN+ LL R L C + +
Sbjct: 274 HAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRG---LRPRCCRRKRRNLETRNL 330
Query: 423 ---HGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRL---LPYMIT 476
+G + L P + P+P +G R + ++ P L P + S + + +M+
Sbjct: 331 DPENGSGMALQPLQAA-PEPGAQGQR-EKNSQHPPALAPPGHQGHSHGHQGGTDITWMVL 388
Query: 477 LGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLL 536
LGD +HN DGLA+GAAF+ + +GL+T+LAVFCHELPHELGDFA LL +GLS R+ LLL
Sbjct: 389 LGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLL 448
Query: 537 NLASALTAFAGLYVALAVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPW 593
+L S G L VG+S W+ V G+FLYVAL DMLPA+L+ +P P
Sbjct: 449 SLVSGALGLGG--AVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPT 506
Query: 594 LLFLLHNVGLLGGWTVLLLLSLYED 618
LL +GLL G ++L ++L E+
Sbjct: 507 PHVLLQGLGLLLGGGLMLAITLLEE 531
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 201 bits (512), Expect = 1e-51
Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 22/385 (5%)
Query: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRP-PVQDQLSQSERYL 303
CL+ ++ +GLS A +TP +A L PALL Q S C P P D LS L
Sbjct: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA---LL 214
Query: 304 YGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLH 363
+LA LL+ L + LLLL G R + +L +LAVG L GDA+LHL P
Sbjct: 215 QSALAVLLLSLPSPLSLLLLRLLGPR-LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGR 273
Query: 364 THSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHS- 422
GL + L++L GL+ F+ EN+ LL R L C + +
Sbjct: 274 HAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRG---LRPRCCRRKRRNLETRNL 330
Query: 423 ---HGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRL---LPYMIT 476
+G + L P + P+P +G R + ++ P L P + S + + +M+
Sbjct: 331 DPENGSGMALQPLQAA-PEPGAQGQR-EKNSQHPPALAPPGHQGHSHGHQGGTDITWMVL 388
Query: 477 LGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLL 536
LGD +HN DGLA+GAAF+ + +GL+T+LAVFCHELPHELGDFA LL +GLS R+ LLL
Sbjct: 389 LGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLL 448
Query: 537 NLASALTAFAGLYVALAVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPW 593
+L S G L VG+S W+ V G+FLYVAL DMLPA+L+ +P P
Sbjct: 449 SLVSGALGLGG--AVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPT 506
Query: 594 LLFLLHNVGLLGGWTVLLLLSLYED 618
LL +GLL G ++L ++L E+
Sbjct: 507 PHVLLQGLGLLLGGGLMLAITLLEE 531
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 197 bits (502), Expect = 2e-50
Identities = 148/482 (30%), Positives = 230/482 (47%), Gaps = 76/482 (15%)
Query: 180 FVDFVFQQHSSEVPMTLAELSALMQRL--GVGREAHSDHSHRHRGASSRDPVPLISSSNS 237
F+ + ++ +TL +L AL+ L GVGR + H HR S+
Sbjct: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLST------------ 90
Query: 238 SSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLS 297
C S+ D+ A+ SEQ+ + + P +LQQ S ACTS+++ +++ +
Sbjct: 91 -------CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQT 143
Query: 298 QSER------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHY--ILQTFLSLAVGALTG 349
+ R + YG L +I LC++ G ++ T Y +L F++LA+G L
Sbjct: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMK---KTFYKRLLLYFIALAIGTLYS 200
Query: 350 DAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDG 409
+A+ L P+ G + + +S + + G Y FF E + +LL + E
Sbjct: 201 NALFQLIPEAFGFNPLEDYYVS-----KSAVVFGGFYLFFFTEKILKILLKQKNEH---- 251
Query: 410 PCGHSSHSHGG---------HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL---- 456
H HSH GV +L +L P H S D A E
Sbjct: 252 ---HHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVG 308
Query: 457 -LNPEPRRLSP------------ELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLA 503
L+ + + S ++ L +MITL D +HNF DGLA+GA+F S G++
Sbjct: 309 SLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGIS 368
Query: 504 TSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAW 563
TS+A+ C E PHELGDF LL+AG+S++QAL N SA + GL + G S S W
Sbjct: 369 TSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG-SHFSANW 427
Query: 564 ILAVATGLFLYVALCDMLPAMLKV--RDPRPWLL---FLLHNVGLLGGWTVLLLLSLYED 618
I A+A G+FLY++L DM P M +V D R + F++ N+GLL G+T++++L++Y
Sbjct: 428 IFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVLTMYSG 487
Query: 619 DI 620
I
Sbjct: 488 QI 489
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 197 bits (502), Expect = 2e-50
Identities = 148/482 (30%), Positives = 230/482 (47%), Gaps = 76/482 (15%)
Query: 180 FVDFVFQQHSSEVPMTLAELSALMQRL--GVGREAHSDHSHRHRGASSRDPVPLISSSNS 237
F+ + ++ +TL +L AL+ L GVGR + H HR S+
Sbjct: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLST------------ 90
Query: 238 SSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLS 297
C S+ D+ A+ SEQ+ + + P +LQQ S ACTS+++ +++ +
Sbjct: 91 -------CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQT 143
Query: 298 QSER------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHY--ILQTFLSLAVGALTG 349
+ R + YG L +I LC++ G ++ T Y +L F++LA+G L
Sbjct: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMK---KTFYKRLLLYFIALAIGTLYS 200
Query: 350 DAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDG 409
+A+ L P+ G + + +S + + G Y FF E + +LL + E
Sbjct: 201 NALFQLIPEAFGFNPLEDYYVS-----KSAVVFGGFYLFFFTEKILKILLKQKNEH---- 251
Query: 410 PCGHSSHSHGG---------HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL---- 456
H HSH GV +L +L P H S D A E
Sbjct: 252 ---HHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVG 308
Query: 457 -LNPEPRRLSP------------ELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLA 503
L+ + + S ++ L +MITL D +HNF DGLA+GA+F S G++
Sbjct: 309 SLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGIS 368
Query: 504 TSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAW 563
TS+A+ C E PHELGDF LL+AG+S++QAL N SA + GL + G S S W
Sbjct: 369 TSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG-SHFSANW 427
Query: 564 ILAVATGLFLYVALCDMLPAMLKV--RDPRPWLL---FLLHNVGLLGGWTVLLLLSLYED 618
I A+A G+FLY++L DM P M +V D R + F++ N+GLL G+T++++L++Y
Sbjct: 428 IFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVLTMYSG 487
Query: 619 DI 620
I
Sbjct: 488 QI 489
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 186 bits (473), Expect = 4e-47
Identities = 138/440 (31%), Positives = 210/440 (47%), Gaps = 59/440 (13%)
Query: 212 AHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQL 271
A H GA+SR VP + CL+A ++ + +G S +T ++ +
Sbjct: 46 AQLQHLLEQMGAASRVGVP-----EPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVI 100
Query: 272 SPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGV 331
PA+LQQ C + RP + + S SE + YG L+ +I L ++ GL+L +
Sbjct: 101 CPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIK-KSY 157
Query: 332 THYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLF 391
IL F+ LA+G L +A+ L P+ G + + + +A+ G Y F F
Sbjct: 158 FPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVE-----KAVAVFGGFYLLFFF 212
Query: 392 ENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSE-LRQPK--PPHEGSRA-- 446
E + +LL ++ GH+H + P E QPK P G
Sbjct: 213 ERMLKMLL--------------KTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYA 258
Query: 447 -------------DLVAEESPELLNPEPRRLS-------PELRLLPYMITLGDAVHNFAD 486
D V+ S + EP + E+ + +MITL DA+HNF D
Sbjct: 259 NPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFID 318
Query: 487 GLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFA 546
GLA+GA+ S GL+TS+A+ C E PHELGDF LL+AG+S RQALL N SA + +
Sbjct: 319 GLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYV 378
Query: 547 GLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPR------PWLLFLLHN 600
GL + VG + + I A+A G+FLY++L DM P M + + + F++ N
Sbjct: 379 GLAFGILVG-NNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQN 437
Query: 601 VGLLGGWTVLLLLSLYEDDI 620
G+L G+T +LL++LY +I
Sbjct: 438 AGMLTGFTAILLITLYAGEI 457
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 186 bits (473), Expect = 4e-47
Identities = 138/440 (31%), Positives = 210/440 (47%), Gaps = 59/440 (13%)
Query: 212 AHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQL 271
A H GA+SR VP + CL+A ++ + +G S +T ++ +
Sbjct: 46 AQLQHLLEQMGAASRVGVP-----EPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVI 100
Query: 272 SPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGV 331
PA+LQQ C + RP + + S SE + YG L+ +I L ++ GL+L +
Sbjct: 101 CPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIK-KSY 157
Query: 332 THYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLF 391
IL F+ LA+G L +A+ L P+ G + + + +A+ G Y F F
Sbjct: 158 FPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVE-----KAVAVFGGFYLLFFF 212
Query: 392 ENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSE-LRQPK--PPHEGSRA-- 446
E + +LL ++ GH+H + P E QPK P G
Sbjct: 213 ERMLKMLL--------------KTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYA 258
Query: 447 -------------DLVAEESPELLNPEPRRLS-------PELRLLPYMITLGDAVHNFAD 486
D V+ S + EP + E+ + +MITL DA+HNF D
Sbjct: 259 NPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFID 318
Query: 487 GLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFA 546
GLA+GA+ S GL+TS+A+ C E PHELGDF LL+AG+S RQALL N SA + +
Sbjct: 319 GLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYV 378
Query: 547 GLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPR------PWLLFLLHN 600
GL + VG + + I A+A G+FLY++L DM P M + + + F++ N
Sbjct: 379 GLAFGILVG-NNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQN 437
Query: 601 VGLLGGWTVLLLLSLYEDDI 620
G+L G+T +LL++LY +I
Sbjct: 438 AGMLTGFTAILLITLYAGEI 457
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 184 bits (466), Expect = 3e-46
Identities = 130/407 (31%), Positives = 200/407 (49%), Gaps = 54/407 (13%)
Query: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLY 304
CL+A ++ + +G S +T ++ + PA+LQQ C + RP + + S SE + Y
Sbjct: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGY 64
Query: 305 GSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHT 364
G L+ +I L ++ GL+L + IL F+ LA+G L +A+ L P+ G
Sbjct: 65 GFLSVTIINLASLLGLILTPLIK-KSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDP 123
Query: 365 HSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHG 424
+ + + +A+ G Y F FE + +LL ++ GH+H
Sbjct: 124 KVDSYVE-----KAVAVFGGFYLLFFFERMLKMLL--------------KTYGQNGHTHF 164
Query: 425 VSLQLAPSE-LRQPK--PPHEGSRA---------------DLVAEESPELLNPEPRRLS- 465
+ P E QPK P G D V+ S + EP +
Sbjct: 165 GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTC 224
Query: 466 ------PELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGD 519
E+ + +MITL DA+HNF DGLA+GA+ S GL+TS+A+ C E PHELGD
Sbjct: 225 LKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGD 284
Query: 520 FAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCD 579
F LL+AG+S RQALL N SA + + GL + VG + + I A+A G+FLY++L D
Sbjct: 285 FVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVG-NNFAPNIIFALAGGMFLYISLAD 343
Query: 580 MLPAMLKVRDPR------PWLLFLLHNVGLLGGWTVLLLLSLYEDDI 620
M P M + + + F++ N G+L G+T +LL++LY +I
Sbjct: 344 MFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 390
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 176 bits (446), Expect = 6e-44
Identities = 133/438 (30%), Positives = 204/438 (46%), Gaps = 71/438 (16%)
Query: 180 FVDFVFQQHSSEVPMTLAELSALMQRL--GVGREAHSDHSHRHRGASSRDPVPLISSSNS 237
F+ + ++ +TL +L AL+ L GVGR + H HR S+
Sbjct: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLST------------ 90
Query: 238 SSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLS 297
C S+ D+ A+ SEQ+ + + P +LQQ S ACTS+++ +++ +
Sbjct: 91 -------CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQT 143
Query: 298 QSER------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHY--ILQTFLSLAVGALTG 349
+ R + YG L +I LC++ G ++ T Y +L F++LA+G L
Sbjct: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMK---KTFYKRLLLYFIALAIGTLYS 200
Query: 350 DAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDG 409
+A+ L P+ G + + +S + + G Y FF E + +LL + E
Sbjct: 201 NALFQLIPEAFGFNPLEDYYVS-----KSAVVFGGFYLFFFTEKILKILLKQKNEH---- 251
Query: 410 PCGHSSHSHGG---------HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL---- 456
H HSH GV +L +L P H S D A E
Sbjct: 252 ---HHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVG 308
Query: 457 -LNPEPRRLSP------------ELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLA 503
L+ + + S ++ L +MITL D +HNF DGLA+GA+F S G++
Sbjct: 309 SLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGIS 368
Query: 504 TSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAW 563
TS+A+ C E PHELGDF LL+AG+S++QAL N SA + GL + G S S W
Sbjct: 369 TSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG-SHFSANW 427
Query: 564 ILAVATGLFLYVALCDML 581
I A+A G+FLY++L DM+
Sbjct: 428 IFALAGGMFLYISLADMM 445
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 170 bits (431), Expect = 3e-42
Identities = 127/398 (31%), Positives = 188/398 (47%), Gaps = 53/398 (13%)
Query: 212 AHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQL 271
A H GA+SR VP + CL+A ++ + +G S +T ++ +
Sbjct: 46 AQLQHLLEQMGAASRVGVP-----EPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVI 100
Query: 272 SPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGV 331
PA+LQQ C + RP + + S SE + YG L+ +I L ++ GL+L +
Sbjct: 101 CPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIK-KSY 157
Query: 332 THYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLF 391
IL F+ LA+G L +A+ L P+ G + + + +A+ G Y F F
Sbjct: 158 FPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVE-----KAVAVFGGFYLLFFF 212
Query: 392 ENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSE-LRQPK--PPHEGSRA-- 446
E + +LL ++ GH+H + P E QPK P G
Sbjct: 213 ERMLKMLL--------------KTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYA 258
Query: 447 -------------DLVAEESPELLNPEPRRLS-------PELRLLPYMITLGDAVHNFAD 486
D V+ S + EP + E+ + +MITL DA+HNF D
Sbjct: 259 NPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFID 318
Query: 487 GLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFA 546
GLA+GA+ S GL+TS+A+ C E PHELGDF LL+AG+S RQALL N SA + +
Sbjct: 319 GLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYV 378
Query: 547 GLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAM 584
GL + VG + + I A+A G+FLY++L DM P M
Sbjct: 379 GLAFGILVG-NNFAPNIIFALAGGMFLYISLADMFPEM 415
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 161 bits (407), Expect = 2e-39
Identities = 93/214 (43%), Positives = 126/214 (58%), Gaps = 38/214 (17%)
Query: 416 HSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMI 475
H H HSHG P H GS DL + + N + +M+
Sbjct: 645 HKHSHHSHG--------------PCHSGS--DL---KETGIAN------------IAWMV 673
Query: 476 TLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALL 535
+GD +HNF+DGLA+GAAF++ G++TS+AVFCHELPHELGDFA LL AG++V+QA++
Sbjct: 674 IMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIV 733
Query: 536 LNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPR--- 591
NL SA+ A+ G+ + AVG + WI AV G+FLYVAL DMLP ML
Sbjct: 734 YNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEH 793
Query: 592 ---PWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 622
P F+L N+GLL G+ ++L+++LYED I F
Sbjct: 794 GFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVF 827
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 14/137 (10%)
Query: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSER--- 301
CL+ ++ YG + ++ + + L PALL Q S C + + +++ +
Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
Query: 302 ----------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDA 351
++ G ++ +I L ++ G++L+ +G ++L ++LAVG ++GDA
Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIIN-QGCFKFLLTFLVALAVGTMSGDA 455
Query: 352 VLHLTPKVLGLHTHSEE 368
+LHL P G H HS +
Sbjct: 456 LLHLLPHSQGGHDHSHQ 472
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 161 bits (407), Expect = 2e-39
Identities = 93/214 (43%), Positives = 126/214 (58%), Gaps = 38/214 (17%)
Query: 416 HSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMI 475
H H HSHG P H GS DL + + N + +M+
Sbjct: 645 HKHSHHSHG--------------PCHSGS--DL---KETGIAN------------IAWMV 673
Query: 476 TLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALL 535
+GD +HNF+DGLA+GAAF++ G++TS+AVFCHELPHELGDFA LL AG++V+QA++
Sbjct: 674 IMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIV 733
Query: 536 LNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPR--- 591
NL SA+ A+ G+ + AVG + WI AV G+FLYVAL DMLP ML
Sbjct: 734 YNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEH 793
Query: 592 ---PWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 622
P F+L N+GLL G+ ++L+++LYED I F
Sbjct: 794 GFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVF 827
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 14/137 (10%)
Query: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSER--- 301
CL+ ++ YG + ++ + + L PALL Q S C + + +++ +
Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
Query: 302 ----------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDA 351
++ G ++ +I L ++ G++L+ +G ++L ++LAVG ++GDA
Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIIN-QGCFKFLLTFLVALAVGTMSGDA 455
Query: 352 VLHLTPKVLGLHTHSEE 368
+LHL P G H HS +
Sbjct: 456 LLHLLPHSQGGHDHSHQ 472
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 154 bits (390), Expect = 2e-37
Identities = 77/157 (49%), Positives = 106/157 (67%), Gaps = 5/157 (3%)
Query: 471 LPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSV 530
L +M+ +GD +HNF+DGLA+GAAF +GL+TS+AVFCHELPHELGDFA LL AG++V
Sbjct: 595 LAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTV 654
Query: 531 RQALLLNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDMLPAML---- 585
+QA+L N SA+ A+ G+ + +G +E WI A+ GLF+YVAL DM+P ML
Sbjct: 655 KQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDA 714
Query: 586 KVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 622
W F L N G+L G+ ++LL+S++E I F
Sbjct: 715 SDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIVF 751
Score = 60.5 bits (145), Expect = 5e-09
Identities = 47/182 (25%), Positives = 81/182 (44%), Gaps = 29/182 (15%)
Query: 245 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGAC---TSQSRPPVQDQL-SQSE 300
C +A ++ ++G+ Q + + L PA++ Q + +C TS+ + + + S
Sbjct: 264 CFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQI 323
Query: 301 RYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVL 360
++ G +A +I ++ G++L+ R ++L ++LAVG L+GDA LHL P
Sbjct: 324 AWVGGFIAISIISFLSLLGVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHLLPHSH 382
Query: 361 GLHTHS------------------------EEGLSPQPTWRLLAMLAGLYAFFLFENLFN 396
H HS EE TW+ L L GLY FL E++
Sbjct: 383 ASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLT 442
Query: 397 LL 398
L+
Sbjct: 443 LI 444
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 146 bits (369), Expect = 5e-35
Identities = 116/368 (31%), Positives = 165/368 (44%), Gaps = 45/368 (12%)
Query: 282 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 341
G P ++ L + Y AT+LI F L L+ +LQ LS
Sbjct: 115 GGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLS 174
Query: 342 LAVGALTGDAVLHLTPKVLGLHTH----------SEEGLSPQPTWRLLAMLAGLYAFFLF 391
A G L GDA LHL P L H+H S G P + L +L+G+ AF +
Sbjct: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLW-VLSGIVAFLVV 233
Query: 392 ENLFNLLLPRDPEDLEDGPCGHS-------SHSHGGHSHG------VSLQLAPSELRQPK 438
E + G GHS SH+ G H HG Q + E ++ +
Sbjct: 234 EKFVRHV---------KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETR 284
Query: 439 PPHEGSRADLVAEESP-ELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASS 497
+ V ++ P N E + +LR+ Y+ D HNF DGLA+GA+F
Sbjct: 285 GVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGG 344
Query: 498 WKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVAL----- 552
G+ T++ V HE+PHE+GDFA L+ +G S +QA+ L L +A+ A AG AL
Sbjct: 345 RGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGG 404
Query: 553 AVG---VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTV 609
AVG W+L G F+YVA +LP +L+ P L LL +GLLGG +
Sbjct: 405 AVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIM 461
Query: 610 LLLLSLYE 617
++L++ E
Sbjct: 462 MVLIAHLE 469
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 146 bits (369), Expect = 5e-35
Identities = 116/368 (31%), Positives = 165/368 (44%), Gaps = 45/368 (12%)
Query: 282 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 341
G P ++ L + Y AT+LI F L L+ +LQ LS
Sbjct: 115 GGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLS 174
Query: 342 LAVGALTGDAVLHLTPKVLGLHTH----------SEEGLSPQPTWRLLAMLAGLYAFFLF 391
A G L GDA LHL P L H+H S G P + L +L+G+ AF +
Sbjct: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLW-VLSGIVAFLVV 233
Query: 392 ENLFNLLLPRDPEDLEDGPCGHS-------SHSHGGHSHG------VSLQLAPSELRQPK 438
E + G GHS SH+ G H HG Q + E ++ +
Sbjct: 234 EKFVRHV---------KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETR 284
Query: 439 PPHEGSRADLVAEESP-ELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASS 497
+ V ++ P N E + +LR+ Y+ D HNF DGLA+GA+F
Sbjct: 285 GVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGG 344
Query: 498 WKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVAL----- 552
G+ T++ V HE+PHE+GDFA L+ +G S +QA+ L L +A+ A AG AL
Sbjct: 345 RGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGG 404
Query: 553 AVG---VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTV 609
AVG W+L G F+YVA +LP +L+ P L LL +GLLGG +
Sbjct: 405 AVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIM 461
Query: 610 LLLLSLYE 617
++L++ E
Sbjct: 462 MVLIAHLE 469
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 130 bits (328), Expect = 3e-30
Identities = 61/112 (54%), Positives = 83/112 (74%), Gaps = 1/112 (0%)
Query: 471 LPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSV 530
L +M+ +GD +HNF+DGLA+GAAF +GL+TS+AVFCHELPHELGDFA LL AG++V
Sbjct: 320 LAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTV 379
Query: 531 RQALLLNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDML 581
+QA+L N SA+ A+ G+ + +G +E WI A+ GLF+YVAL DM+
Sbjct: 380 KQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMV 431
Score = 52.0 bits (123), Expect = 2e-06
Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 29/156 (18%)
Query: 271 LSPALLQQQLSGAC---TSQSRPPVQDQL-SQSERYLYGSLATLLICLCAVFGLLLLTCT 326
L PA++ Q + +C TS+ + + + S ++ G +A +I ++ G++L+
Sbjct: 15 LCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLM 74
Query: 327 GCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHS-------------------- 366
R ++L ++LAVG L+GDA LHL P H HS
Sbjct: 75 N-RVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLS 133
Query: 367 ----EEGLSPQPTWRLLAMLAGLYAFFLFENLFNLL 398
EE TW+ L L GLY FL E++ L+
Sbjct: 134 SQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLI 169
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 116 bits (291), Expect = 5e-26
Identities = 113/366 (30%), Positives = 165/366 (45%), Gaps = 56/366 (15%)
Query: 273 PALLQQQLSGACTSQSRPPVQ-DQLSQSER---YLYGSLATLLICLCAVFGLLLLTC--- 325
PAL + + AC ++ L ER ++ L +L++ L VF LL++
Sbjct: 35 PALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMG 94
Query: 326 TGCRGVTH-YILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSE---EGLSPQPTWRL-LA 380
T R + L+ LS A+G L G+ LHL P+ + EG S Q +L L
Sbjct: 95 TMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLW 154
Query: 381 MLAGLYAFFLFENLFNLLLPRDPEDLEDGP----CGHSSHSHGGHSHGVSLQLAPSELRQ 436
++AG+ F E +F L E P ++ +GGH L Q
Sbjct: 155 VIAGILTFLALEKMF---LDSKEEGTSQAPNKDPTAAAAALNGGHC-----------LAQ 200
Query: 437 PKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFAS 496
P P + +++ Y+ L + + NF GLAV A+F
Sbjct: 201 PAA------------------EPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLV 242
Query: 497 SWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAV-- 554
S K GL T++A+ HE+PHE+GDFA LL AG A L L++AL G A+
Sbjct: 243 SKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQS 302
Query: 555 --GVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLL 612
GV EE+ AW+L +G FLY+AL ++LP +L+ DP L LL L G V++L
Sbjct: 303 PKGV-EETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLL---LCAGIVVMVL 358
Query: 613 LSLYED 618
SL+ D
Sbjct: 359 FSLFVD 364
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 115 bits (289), Expect = 9e-26
Identities = 114/372 (30%), Positives = 166/372 (44%), Gaps = 61/372 (16%)
Query: 273 PALLQQQLSGACTSQSRPPVQ-DQLSQSER---YLYGSLATLLICLCAVFGLLLLTC--- 325
PAL + + AC ++ L ER ++ L +L++ L VF LL++
Sbjct: 35 PALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMG 94
Query: 326 TGCRGVTH-YILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSE---EGLSPQPTWRL-LA 380
T R + L+ LS A+G L G+ LHL P+ + EG S Q +L L
Sbjct: 95 TMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLW 154
Query: 381 MLAGLYAFFLFENLFNLLLPRDPEDLEDGP----CGHSSHSHGGHSHGVSLQLAPSELRQ 436
++AG+ F E +F L E P ++ +GGH L Q
Sbjct: 155 VIAGILTFLALEKMF---LDSKEEGTSQAPNKDPTAAAAALNGGHC-----------LAQ 200
Query: 437 PKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFAS 496
P P + +++ Y+ L + + NF GLAV A+F
Sbjct: 201 PAA------------------EPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLV 242
Query: 497 SWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVAL---- 552
S K GL T++A+ HE+PHE+GDFA LL AG A L L++AL G A+
Sbjct: 243 SKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQS 302
Query: 553 ---AVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGG 606
VG S EE+ AW+L +G FLY+AL ++LP +L+ DP L LL L G
Sbjct: 303 PKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLL---LCAG 359
Query: 607 WTVLLLLSLYED 618
V++L SL+ D
Sbjct: 360 IVVMVLFSLFVD 371
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 476 TLGDAVHNFADGLAVGAAFASS-WKTGLATSLAVFCHELPHELGDFAALLHAGLS---VR 531
TLG VH ADG+A+GAA ++S L +A+ H+ P G + L+HAGL +R
Sbjct: 149 TLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIR 208
Query: 532 QALLLNLASA----LTAFAGLYVALAVGVSEESEAWI-LAVATGLFLYVALCDMLP 582
+ LL+ +A + + GL + +SE + + + + G FLYVA +LP
Sbjct: 209 KHLLVFALAAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLP 264
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 50.1 bits (118), Expect = 6e-06
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 474 MITLGDAVHNFADGLAVGAAFASSWKTGLAT-------SLAVFCHELPHELGDFAALLHA 526
++ L +HN +GLAVG F + KT AT ++ + P L L A
Sbjct: 196 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 255
Query: 527 GLSVRQALLLN-LASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCDMLP 582
G S +A L+ + AG++ A AV ++E + LA A G +YV + D++P
Sbjct: 256 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIP 312
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 50.1 bits (118), Expect = 6e-06
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 474 MITLGDAVHNFADGLAVGAAFASSWKTGLAT-------SLAVFCHELPHELGDFAALLHA 526
++ L +HN +GLAVG F + KT AT ++ + P L L A
Sbjct: 189 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 248
Query: 527 GLSVRQALLLN-LASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCDMLP 582
G S +A L+ + AG++ A AV ++E + LA A G +YV + D++P
Sbjct: 249 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIP 305
>gi|156415986 solute carrier family 39 (zinc transporter), member 2
[Homo sapiens]
Length = 309
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/124 (36%), Positives = 61/124 (49%), Gaps = 10/124 (8%)
Query: 468 LRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAG 527
LR L +++L + H+ +GLAVG + L LAV H+ G L+H G
Sbjct: 163 LRALVLLLSL--SFHSVFEGLAVGLQPTVAATVQLC--LAVLAHKGLVVFGVGMRLVHLG 218
Query: 528 LSVRQALLLNLASALTAFAGLYVALAV--GVSEE----SEAWILAVATGLFLYVALCDML 581
S R A+ L AL + GL V LAV G SE ++A + VA G FLYV ++L
Sbjct: 219 TSSRWAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEIL 278
Query: 582 PAML 585
P L
Sbjct: 279 PREL 282
>gi|124378039 SEC16 homolog A [Homo sapiens]
Length = 2357
Score = 36.2 bits (82), Expect = 0.093
Identities = 26/61 (42%), Positives = 33/61 (54%), Gaps = 8/61 (13%)
Query: 12 GPRGSPW--PGLPLPSLVGPAPLLTCLCPQCLSVEDALGLGEPEGSGLPPG--PVLEARY 67
GP SP P P+P + P PL P C++ ALG EP G GLPPG P+ E R+
Sbjct: 1960 GPLASPARVPMFPVP--LPPGPLEPG--PGCVTPGPALGFLEPSGPGLPPGVPPLQERRH 2015
Query: 68 V 68
+
Sbjct: 2016 L 2016
>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
Length = 1243
Score = 33.1 bits (74), Expect = 0.78
Identities = 31/103 (30%), Positives = 44/103 (42%), Gaps = 18/103 (17%)
Query: 191 EVPMTLAELSALMQRLGVGREAHSDHSHRHRGASSRDPVPLISSSNSSSVW-----DTVC 245
E LAE + LG G E D + S P+ S+ S VW ++C
Sbjct: 1065 ETREALAESDRAAEGLGAGVEEEGDDGKEPQVGGSPQPL-----SHPSPVWMNYSYSSLC 1119
Query: 246 LSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQS 288
LS+ + SE +G E WA+L +L Q+ LS T Q+
Sbjct: 1120 LSSEE-------SESSGEDEEFWAELQ-SLRQKHLSEVETLQT 1154
>gi|239741896 PREDICTED: hypothetical protein XP_002342335 [Homo
sapiens]
Length = 347
Score = 33.1 bits (74), Expect = 0.78
Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 2/61 (3%)
Query: 207 GVGREAHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPE 266
G+ ++H +H H+GAS PL S+ VW + CL+ +G EQ PE
Sbjct: 285 GLRIQSHPGTTHLHQGASFTSSEPLSGISSPRGVWASGCLAPFPQPLIHG--EQRRALPE 342
Query: 267 A 267
A
Sbjct: 343 A 343
>gi|23308499 zinc finger protein 488 [Homo sapiens]
Length = 340
Score = 32.7 bits (73), Expect = 1.0
Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 14/120 (11%)
Query: 38 PQCLSVEDALGLGEPEGSGLPPGPVLEARY------VARLSAAAVLYLSNPEG-TCEDAR 90
P CLSV AL + G G P P E R+ + R +L +N G R
Sbjct: 5 PPCLSVAPALVITMAAGKGAPLSPSAENRWRLSEPELGRGCKPVLLEKTNRLGPEAAVGR 64
Query: 91 AGLWASHADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKTACVDIPQLLEEAVGAGA 150
AG A+ LALL +P PG + + + G+ ++A ++P++ + V A A
Sbjct: 65 AGRDVGSAE--LALLVAPGKPRPG-----KPLPPKTRGEQRQSAFTELPRMKDRQVDAQA 117
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,101,914
Number of Sequences: 37866
Number of extensions: 1412034
Number of successful extensions: 4528
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 4380
Number of HSP's gapped (non-prelim): 91
length of query: 622
length of database: 18,247,518
effective HSP length: 108
effective length of query: 514
effective length of database: 14,157,990
effective search space: 7277206860
effective search space used: 7277206860
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.