Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 224593764
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224593764 CDC20 cell division cycle 20 homolog B isoform 2
[Homo sapiens]
(477 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224593764 CDC20 cell division cycle 20 homolog B isoform 2 [H... 974 0.0
gi|22749275 CDC20 cell division cycle 20 homolog B isoform 1 [Ho... 936 0.0
gi|118402582 cell division cycle 20 [Homo sapiens] 250 2e-66
gi|209969680 Fzr1 protein isoform 1 [Homo sapiens] 174 2e-43
gi|33620742 Fzr1 protein isoform 2 [Homo sapiens] 174 2e-43
gi|209969678 Fzr1 protein isoform 3 [Homo sapiens] 140 2e-33
gi|13376840 WD repeat domain 61 [Homo sapiens] 65 2e-10
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 60 4e-09
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 59 1e-08
gi|23199987 WD repeat domain 5B [Homo sapiens] 58 2e-08
gi|16554629 WD repeat domain 5 [Homo sapiens] 57 3e-08
gi|16554627 WD repeat domain 5 [Homo sapiens] 57 3e-08
gi|19913367 transducin beta-like 1Y [Homo sapiens] 57 4e-08
gi|19913365 transducin beta-like 1Y [Homo sapiens] 57 4e-08
gi|15150805 transducin beta-like 1Y [Homo sapiens] 57 4e-08
gi|62234438 Notchless gene homolog isoform b [Homo sapiens] 55 1e-07
gi|32189425 WD repeat domain 69 [Homo sapiens] 55 2e-07
gi|21071067 TBP-associated factor 5 [Homo sapiens] 54 2e-07
gi|113865883 WD repeat domain 38 [Homo sapiens] 54 2e-07
gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is... 54 3e-07
gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i... 54 3e-07
gi|157739942 gemin 5 [Homo sapiens] 52 9e-07
gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 52 9e-07
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 49 8e-06
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 48 2e-05
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 48 2e-05
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 48 2e-05
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 48 2e-05
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 48 2e-05
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 47 4e-05
>gi|224593764 CDC20 cell division cycle 20 homolog B isoform 2 [Homo
sapiens]
Length = 477
Score = 974 bits (2519), Expect = 0.0
Identities = 477/477 (100%), Positives = 477/477 (100%)
Query: 1 MEWKLERTAPRRVRTEEEMLWESIMRVLSKDLKQKRSQDSANVLDSVNATYSDFKSNFAK 60
MEWKLERTAPRRVRTEEEMLWESIMRVLSKDLKQKRSQDSANVLDSVNATYSDFKSNFAK
Sbjct: 1 MEWKLERTAPRRVRTEEEMLWESIMRVLSKDLKQKRSQDSANVLDSVNATYSDFKSNFAK 60
Query: 61 RLSAEVPVASSPITTRWQQSQTRALSSDSFGEEQSTTYLPEASGSVLKTPPEKETLTLGS 120
RLSAEVPVASSPITTRWQQSQTRALSSDSFGEEQSTTYLPEASGSVLKTPPEKETLTLGS
Sbjct: 61 RLSAEVPVASSPITTRWQQSQTRALSSDSFGEEQSTTYLPEASGSVLKTPPEKETLTLGS 120
Query: 121 RKEQLKTPSKGISETSNSALHFCKAPHAMDRDWKESVASKGQKCLKQLFVTQNVVQQANG 180
RKEQLKTPSKGISETSNSALHFCKAPHAMDRDWKESVASKGQKCLKQLFVTQNVVQQANG
Sbjct: 121 RKEQLKTPSKGISETSNSALHFCKAPHAMDRDWKESVASKGQKCLKQLFVTQNVVQQANG 180
Query: 181 KMQLCEQSECVWKGCKDGVRDESFHLKSSGDINDSILQPEVKIHITGLRNDYYLNILDWS 240
KMQLCEQSECVWKGCKDGVRDESFHLKSSGDINDSILQPEVKIHITGLRNDYYLNILDWS
Sbjct: 181 KMQLCEQSECVWKGCKDGVRDESFHLKSSGDINDSILQPEVKIHITGLRNDYYLNILDWS 240
Query: 241 FQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLW 300
FQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLW
Sbjct: 241 FQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLW 300
Query: 301 DVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCA 360
DVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCA
Sbjct: 301 DVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCA 360
Query: 361 LKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIAT 420
LKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIAT
Sbjct: 361 LKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIAT 420
Query: 421 GQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWNCY 477
GQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWNCY
Sbjct: 421 GQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWNCY 477
>gi|22749275 CDC20 cell division cycle 20 homolog B isoform 1 [Homo
sapiens]
Length = 515
Score = 936 bits (2419), Expect = 0.0
Identities = 472/519 (90%), Positives = 472/519 (90%), Gaps = 46/519 (8%)
Query: 1 MEWKLERTAPRRVRTEEEMLWESIMRVLSKDLKQKRSQDSANVLDSVNATYSDFKSNFAK 60
MEWKLERTAPRRVRTEEEMLWESIMRVLSKDLKQKRSQDSANVLDSVNATYSDFKSNFAK
Sbjct: 1 MEWKLERTAPRRVRTEEEMLWESIMRVLSKDLKQKRSQDSANVLDSVNATYSDFKSNFAK 60
Query: 61 RLSAEVPVASSPITTRWQQSQTRALSSDSFGEEQSTTYLPEASGSVLKTPPEKETLTLGS 120
RLSAEVPVASSPITTRWQQSQTRALSSDSFGEEQSTTYLPEASGSVLKTPPEKETLTLGS
Sbjct: 61 RLSAEVPVASSPITTRWQQSQTRALSSDSFGEEQSTTYLPEASGSVLKTPPEKETLTLGS 120
Query: 121 RKEQLKTPSKGISETSNSALHFCKAPHAMDRDWKESVASKGQKCLKQLFVTQNVVQQANG 180
KEQLKTPSKGISETSNSALHFCKAPHAMDRDWKESVASKGQKCLKQLFVTQNVVQQANG
Sbjct: 121 CKEQLKTPSKGISETSNSALHFCKAPHAMDRDWKESVASKGQKCLKQLFVTQNVVQQANG 180
Query: 181 KMQLCEQSECVWKGCKDGVRDESFHLKSSGDINDSILQPEVKIHITGLRNDYYLNILDWS 240
KMQLCEQSECVWKGCKDGVRDESFHLKSSGDINDSILQPEVKIHITGLRNDYYLNILDWS
Sbjct: 181 KMQLCEQSECVWKGCKDGVRDESFHLKSSGDINDSILQPEVKIHITGLRNDYYLNILDWS 240
Query: 241 FQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLW 300
FQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLW
Sbjct: 241 FQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLW 300
Query: 301 DVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCA 360
DVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCA
Sbjct: 301 DVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCA 360
Query: 361 LKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVK--------------- 405
LKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVK
Sbjct: 361 LKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKAMDWCPWQSGVLAIG 420
Query: 406 ---------------------------ICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVS 438
ICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVS
Sbjct: 421 GGMKDGRLHILDINAGKSIQTPSTNSQICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVS 480
Query: 439 RSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWNCY 477
RS GHRGRVLHLALSPDQTRVFSAAADGTASVWNCY
Sbjct: 481 RS----GHRGRVLHLALSPDQTRVFSAAADGTASVWNCY 515
>gi|118402582 cell division cycle 20 [Homo sapiens]
Length = 499
Score = 250 bits (638), Expect = 2e-66
Identities = 129/294 (43%), Positives = 174/294 (59%), Gaps = 45/294 (15%)
Query: 228 LRNDYYLNILDWSFQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTC 287
+RNDYYLN++DWS N++A+AL ++VY+W+ + + ++ + + YISSV+WIKEG
Sbjct: 181 IRNDYYLNLVDWSSGNVLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNY 240
Query: 288 LAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQH 347
LAVGTS EVQLWDV +KRLRNM H + VG+LSWN +ILSSGSR G ++HHDVRVA+H
Sbjct: 241 LAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWNSYILSSGSRSGHIHHHDVRVAEH 300
Query: 348 HVGTLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQST-AVK 405
HV TL H Q VC L+W+PDGR L+SG +D L+ +WP PG PL+ TQ AVK
Sbjct: 301 HVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW-VPLQTFTQHQGAVK 359
Query: 406 ------------------------------------------ICSLIWLPKTKEIATGQG 423
+CS++W P KE+ +G G
Sbjct: 360 AVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQVCSILWSPHYKELISGHG 419
Query: 424 TPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWNCY 477
+N + +W PT+++ GH RVL L +SPD V SAAAD T +W C+
Sbjct: 420 FAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDGATVASAAADETLRLWRCF 473
>gi|209969680 Fzr1 protein isoform 1 [Homo sapiens]
Length = 496
Score = 174 bits (441), Expect = 2e-43
Identities = 99/292 (33%), Positives = 147/292 (50%), Gaps = 44/292 (15%)
Query: 228 LRNDYYLNILDWSFQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTC 287
L++D+YLN++DWS N++++ LG+ VY+W+ DLS+ + ++SV W + G
Sbjct: 184 LQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNL 243
Query: 288 LAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRV--A 345
+AVGT +G VQ+WD K+L + GH + VGAL+WN LSSGSR + D+R
Sbjct: 244 VAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPL 303
Query: 346 QHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIW----------------------- 382
Q H+Q VC LKWS D +LL+SG +D L +W
Sbjct: 304 QSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAW 363
Query: 383 -PHDPGASAQ----------------GQPLKVITQSTAVKICSLIWLPKTKEIATGQGTP 425
PH G A GQPL+ I T ++C+L W E+ + G
Sbjct: 364 SPHQHGLLASGGGTADRCIRFWNTLTGQPLQCI--DTGSQVCNLAWSKHANELVSTHGYS 421
Query: 426 KNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWNCY 477
+N + VW P++++ GH RVL+LA+SPD + + A D T WN +
Sbjct: 422 QNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVF 473
>gi|33620742 Fzr1 protein isoform 2 [Homo sapiens]
Length = 493
Score = 174 bits (441), Expect = 2e-43
Identities = 99/292 (33%), Positives = 147/292 (50%), Gaps = 44/292 (15%)
Query: 228 LRNDYYLNILDWSFQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTC 287
L++D+YLN++DWS N++++ LG+ VY+W+ DLS+ + ++SV W + G
Sbjct: 184 LQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNL 243
Query: 288 LAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRV--A 345
+AVGT +G VQ+WD K+L + GH + VGAL+WN LSSGSR + D+R
Sbjct: 244 VAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPL 303
Query: 346 QHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIW----------------------- 382
Q H+Q VC LKWS D +LL+SG +D L +W
Sbjct: 304 QSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAW 363
Query: 383 -PHDPGASAQ----------------GQPLKVITQSTAVKICSLIWLPKTKEIATGQGTP 425
PH G A GQPL+ I T ++C+L W E+ + G
Sbjct: 364 SPHQHGLLASGGGTADRCIRFWNTLTGQPLQCI--DTGSQVCNLAWSKHANELVSTHGYS 421
Query: 426 KNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWNCY 477
+N + VW P++++ GH RVL+LA+SPD + + A D T WN +
Sbjct: 422 QNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVF 473
>gi|209969678 Fzr1 protein isoform 3 [Homo sapiens]
Length = 404
Score = 140 bits (354), Expect = 2e-33
Identities = 85/252 (33%), Positives = 121/252 (48%), Gaps = 44/252 (17%)
Query: 268 DLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFI 327
DLS+ + ++SV W + G +AVGT +G VQ+WD K+L + GH + VGAL+WN
Sbjct: 135 DLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQ 194
Query: 328 LSSGSRLGRVYHHDVRVA--QHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIW--- 382
LSSGSR + D+R Q H+Q VC LKWS D +LL+SG +D L +W
Sbjct: 195 LSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHS 254
Query: 383 ---------------------PHDPGASAQG----------------QPLKVITQSTAVK 405
PH G A G QPL+ I T +
Sbjct: 255 SLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCI--DTGSQ 312
Query: 406 ICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSA 465
+C+L W E+ + G +N + VW P++++ GH RVL+LA+SPD + +
Sbjct: 313 VCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTG 372
Query: 466 AADGTASVWNCY 477
A D T WN +
Sbjct: 373 AGDETLRFWNVF 384
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 64.7 bits (156), Expect = 2e-10
Identities = 53/223 (23%), Positives = 107/223 (47%), Gaps = 23/223 (10%)
Query: 256 WNGENHN-GIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNM-LG 313
W+ E H G+ ++D+S T +S S + ++LWD+ K+++++ G
Sbjct: 58 WSLEGHQLGVVSVDISHTLPIAASSSL------------DAHIRLWDLENGKQIKSIDAG 105
Query: 314 HLSV-VGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSS 372
+ A S + L++G+ +G+V V + + + ++ +SPDG+ L+S
Sbjct: 106 PVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLAS 165
Query: 373 GCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVW 432
G DG++ I+ A G+ L + + A+ I SL + P ++ + T + + ++
Sbjct: 166 GAIDGIINIFD-----IATGKLLHTL-EGHAMPIRSLTFSPDSQLLVT--ASDDGYIKIY 217
Query: 433 TCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
+ +G GH VL++A PD T S+++D + VW+
Sbjct: 218 DVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWD 260
Score = 45.8 bits (107), Expect = 8e-05
Identities = 48/231 (20%), Positives = 99/231 (42%), Gaps = 12/231 (5%)
Query: 248 ALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKR 307
+L + + +W+ EN I++ID + ++++ + LA GT G+V ++ V + K+
Sbjct: 83 SLDAHIRLWDLENGKQIKSIDAGPVDAW--TLAFSPDSQYLATGTHVGKVNIFGVESGKK 140
Query: 308 LRNM--LGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSP 365
++ G + A S + L+SG+ G + D+ + H + +L +SP
Sbjct: 141 EYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSP 200
Query: 366 DGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTP 425
D +LL + DG + I+ Q L A + ++ + P +
Sbjct: 201 DSQLLVTASDDGYIKIY------DVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSD- 253
Query: 426 KNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWNC 476
V VW T + FF H+ +V + + + +++ S D +++C
Sbjct: 254 -KSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYDC 303
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 60.1 bits (144), Expect = 4e-09
Identities = 51/191 (26%), Positives = 84/191 (43%), Gaps = 22/191 (11%)
Query: 214 DSILQPEVKIHITGLRNDYYLNILDWSFQNLVAIALG-SAVYIWNGENHNGIENIDLS-- 270
D I QP+ + + + L+ + ++++A + Y+ +G + DLS
Sbjct: 89 DIIYQPQAIFRVRAVTR--CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTE 146
Query: 271 ---LTC----NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRL-RNMLGHLSVVGALS 322
TC +++ S+SW +G LA G G++ LWD T K++ R + GH + LS
Sbjct: 147 TPHFTCKGHRHWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLS 206
Query: 323 WNHF-------ILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCS 375
W ++S S+ G V D + H Q+V L+W DG LL S
Sbjct: 207 WEPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQ 265
Query: 376 DGLLTIW-PHD 385
D + +W HD
Sbjct: 266 DRTIKVWRAHD 276
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/109 (30%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Query: 276 ISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--HFILSSGSR 333
I+ V + + +A + + ++LWD T K L ++ GH++ V ++W+ +L SGS
Sbjct: 375 INQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSS 434
Query: 334 LGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIW 382
+ DV+ + + H V A+ WSPDG+ ++SG D L IW
Sbjct: 435 DSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 50.1 bits (118), Expect = 4e-06
Identities = 44/156 (28%), Positives = 65/156 (41%), Gaps = 15/156 (9%)
Query: 328 LSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPG 387
L+SGS V D+ H H+ V ++ WSPDGR L+SGC +G + +W DP
Sbjct: 129 LASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGRKLASGCKNGQILLW--DPS 186
Query: 388 ASAQ-GQPLKVITQSTAVKICSLIW-----LPKTKEIATGQGTPKNDVTVWTCPTVSRSG 441
Q G+ L + I L W P+ + +A+ + V +W
Sbjct: 187 TGKQVGRTL----AGHSKWITGLSWEPLHANPECRYVAS--SSKDGSVRIWDTTAGRCER 240
Query: 442 GFFGHRGRVLHLALSPDQTRVFSAAADGTASVWNCY 477
GH V L D ++SA+ D T VW +
Sbjct: 241 ILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAH 275
Score = 36.2 bits (82), Expect = 0.067
Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 14/124 (11%)
Query: 354 HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPG---ASAQGQPLKVITQSTAVKICSLI 410
H+ + + +SPD R+++S D + +W G AS +G + +
Sbjct: 371 HQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGH---------VAAVYQIA 421
Query: 411 WLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGT 470
W ++ + +G + + VW + GH V + SPD RV S D
Sbjct: 422 WSADSRLLVSGSSD--STLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKC 479
Query: 471 ASVW 474
+W
Sbjct: 480 LRIW 483
Score = 34.7 bits (78), Expect = 0.20
Identities = 57/299 (19%), Positives = 98/299 (32%), Gaps = 52/299 (17%)
Query: 224 HITGLRNDYYLNILDWS--FQNLVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSW 281
H T + +++ + WS + L + + +W+ + L+ +I+ +SW
Sbjct: 149 HFTCKGHRHWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQVGRT-LAGHSKWITGLSW 207
Query: 282 IK-----EGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGR 336
E +A + +G V++WD + R + GH V L W G
Sbjct: 208 EPLHANPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWG----GDGLLYSA 263
Query: 337 VYHHDVRVAQHHVGTL-----RHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQ 391
++V + H G L H V + S D L + ++ P D S Q
Sbjct: 264 SQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQ 323
Query: 392 GQPLKVITQSTAVK-------------ICSLIWLP----KTKEIATGQGTPKNDVT---- 430
+ +++ V+ +W P K TG N V
Sbjct: 324 ELKERALSRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD 383
Query: 431 --------------VWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
+W T GH V +A S D + S ++D T VW+
Sbjct: 384 SRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD 442
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 58.5 bits (140), Expect = 1e-08
Identities = 50/204 (24%), Positives = 87/204 (42%), Gaps = 10/204 (4%)
Query: 274 NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--HFILSSG 331
N S V G LA G + V LW + + ++ GH S V ++ N ++ +G
Sbjct: 22 NVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAG 81
Query: 332 SRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQ 391
S+ G + D+ A+ + HK +C+L + P G ++SG D + +W +
Sbjct: 82 SQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW----DIRRK 137
Query: 392 GQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVL 451
G + S AV+ L + P K +A+ + V +W F GH G V
Sbjct: 138 GCVFRYRGHSQAVR--CLRFSPDGKWLAS--AADDHTVKLWDLTAGKMMSEFPGHTGPVN 193
Query: 452 HLALSPDQTRVFSAAADGTASVWN 475
+ P++ + S ++D T W+
Sbjct: 194 VVEFHPNEYLLASGSSDRTIRFWD 217
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 2/97 (2%)
Query: 284 EGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSW--NHFILSSGSRLGRVYHHD 341
+G LA + V+LWD+ K + GH V + + N ++L+SGS + D
Sbjct: 158 DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWD 217
Query: 342 VRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGL 378
+ Q V ++ ++PDG L SGC D L
Sbjct: 218 LEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSL 254
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 57.8 bits (138), Expect = 2e-08
Identities = 51/205 (24%), Positives = 87/205 (42%), Gaps = 12/205 (5%)
Query: 276 ISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--HFILSSGSR 333
IS V+W + + L + + ++LWDV + K L+ + GH + V ++N ++ SGS
Sbjct: 86 ISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSF 145
Query: 334 LGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQ 393
V +V+ + H V A+ ++ G L+ SG DGL IW +A GQ
Sbjct: 146 DETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWD-----AASGQ 200
Query: 394 PLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHL 453
LK + + + + P K I T T N + +W + GH+ +
Sbjct: 201 CLKTLVDDDNPPVSFVKFSPNGKYILT--ATLDNTLKLWDYSRGRCLKTYTGHKNEKYCI 258
Query: 454 ALSPDQTR---VFSAAADGTASVWN 475
+ T + S + D +WN
Sbjct: 259 FANFSVTGGKWIVSGSEDNLVYIWN 283
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/207 (25%), Positives = 85/207 (41%), Gaps = 12/207 (5%)
Query: 274 NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--HFILSSG 331
NY+ ++ + G+ + V++W+V T K L+ + H V A+ +N ++ SG
Sbjct: 126 NYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSG 185
Query: 332 SRLGRVYHHDVRVAQHHVGTL--RHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGAS 389
S G D Q + TL V +K+SP+G+ + + D L +W +
Sbjct: 186 SYDGLCRIWDAASGQ-CLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDY----- 239
Query: 390 AQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGR 449
++G+ LK T K C T G+ N V +W T GH
Sbjct: 240 SRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDV 299
Query: 450 VLHLALSPDQTRVFSAAA--DGTASVW 474
V+ A P + + SAA D T +W
Sbjct: 300 VISAACHPTENLIASAALENDKTIKLW 326
Score = 37.4 bits (85), Expect = 0.030
Identities = 26/121 (21%), Positives = 51/121 (42%), Gaps = 8/121 (6%)
Query: 354 HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLP 413
H +AV ++K+SP+G L+S +D L+ IW + G+ K + ++I + W
Sbjct: 40 HTEAVSSVKFSPNGEWLASSSADRLIIIW-----GAYDGKYEKTL-YGHNLEISDVAWSS 93
Query: 414 KTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASV 473
+ + + + + +W + GH V +P + S + D T +
Sbjct: 94 DSSRLVS--ASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKI 151
Query: 474 W 474
W
Sbjct: 152 W 152
Score = 35.8 bits (81), Expect = 0.088
Identities = 32/149 (21%), Positives = 60/149 (40%), Gaps = 17/149 (11%)
Query: 265 ENIDLSLTCNYI------SSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVV 318
EN + +L C + SSV + G LA +++ + +W K + + GH +
Sbjct: 27 ENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEI 86
Query: 319 GALSW----NHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGC 374
++W + + +S + +++ DVR + H V ++P L+ SG
Sbjct: 87 SDVAWSSDSSRLVSASDDKTLKLW--DVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGS 144
Query: 375 SDGLLTIWPHDPG-----ASAQGQPLKVI 398
D + IW G SA P+ +
Sbjct: 145 FDETVKIWEVKTGKCLKTLSAHSDPVSAV 173
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 57.4 bits (137), Expect = 3e-08
Identities = 50/205 (24%), Positives = 85/205 (41%), Gaps = 12/205 (5%)
Query: 276 ISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--HFILSSGSR 333
IS V+W + L + + +++WDV + K L+ + GH + V ++N ++ SGS
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSF 149
Query: 334 LGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQ 393
V DV+ + H V A+ ++ DG L+ S DGL IW +A GQ
Sbjct: 150 DESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD-----TASGQ 204
Query: 394 PLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHL 453
LK + + + + P K I T N + +W + GH+ +
Sbjct: 205 CLKTLIDDDNPPVSFVKFSPNGKYILA--ATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 454 ALSPDQTR---VFSAAADGTASVWN 475
+ T + S + D +WN
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIWN 287
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/209 (24%), Positives = 86/209 (41%), Gaps = 16/209 (7%)
Query: 274 NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNH----FILS 329
NY+ ++ + + G+ + V++WDV T K L+ + H V A+ +N + S
Sbjct: 130 NYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSS 189
Query: 330 SGSRLGRVYHHDVRVAQHHVGTL--RHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPG 387
S L R++ + + TL V +K+SP+G+ + + D L +W +
Sbjct: 190 SYDGLCRIWD---TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY--- 243
Query: 388 ASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHR 447
++G+ LK T K C T G+ N V +W T GH
Sbjct: 244 --SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHT 301
Query: 448 GRVLHLALSPDQTRVFSAAA--DGTASVW 474
V+ A P + + SAA D T +W
Sbjct: 302 DVVISTACHPTENIIASAALENDKTIKLW 330
Score = 35.8 bits (81), Expect = 0.088
Identities = 26/122 (21%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 354 HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLP 413
H +AV ++K+SP+G L+S +D L+ IW + G+ K I+ + I + W
Sbjct: 44 HTKAVSSVKFSPNGEWLASSSADKLIKIW-----GAYDGKFEKTIS-GHKLGISDVAWSS 97
Query: 414 KTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASV 473
+ + + + + +W + GH V +P + S + D + +
Sbjct: 98 DSNLLVS--ASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRI 155
Query: 474 WN 475
W+
Sbjct: 156 WD 157
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 57.4 bits (137), Expect = 3e-08
Identities = 50/205 (24%), Positives = 85/205 (41%), Gaps = 12/205 (5%)
Query: 276 ISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--HFILSSGSR 333
IS V+W + L + + +++WDV + K L+ + GH + V ++N ++ SGS
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSF 149
Query: 334 LGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQ 393
V DV+ + H V A+ ++ DG L+ S DGL IW +A GQ
Sbjct: 150 DESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWD-----TASGQ 204
Query: 394 PLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHL 453
LK + + + + P K I T N + +W + GH+ +
Sbjct: 205 CLKTLIDDDNPPVSFVKFSPNGKYILA--ATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 454 ALSPDQTR---VFSAAADGTASVWN 475
+ T + S + D +WN
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIWN 287
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/209 (24%), Positives = 86/209 (41%), Gaps = 16/209 (7%)
Query: 274 NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNH----FILS 329
NY+ ++ + + G+ + V++WDV T K L+ + H V A+ +N + S
Sbjct: 130 NYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSS 189
Query: 330 SGSRLGRVYHHDVRVAQHHVGTL--RHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPG 387
S L R++ + + TL V +K+SP+G+ + + D L +W +
Sbjct: 190 SYDGLCRIWD---TASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY--- 243
Query: 388 ASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHR 447
++G+ LK T K C T G+ N V +W T GH
Sbjct: 244 --SKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHT 301
Query: 448 GRVLHLALSPDQTRVFSAAA--DGTASVW 474
V+ A P + + SAA D T +W
Sbjct: 302 DVVISTACHPTENIIASAALENDKTIKLW 330
Score = 35.8 bits (81), Expect = 0.088
Identities = 26/122 (21%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 354 HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLP 413
H +AV ++K+SP+G L+S +D L+ IW + G+ K I+ + I + W
Sbjct: 44 HTKAVSSVKFSPNGEWLASSSADKLIKIW-----GAYDGKFEKTIS-GHKLGISDVAWSS 97
Query: 414 KTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASV 473
+ + + + + +W + GH V +P + S + D + +
Sbjct: 98 DSNLLVS--ASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRI 155
Query: 474 WN 475
W+
Sbjct: 156 WD 157
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 57.0 bits (136), Expect = 4e-08
Identities = 86/385 (22%), Positives = 140/385 (36%), Gaps = 79/385 (20%)
Query: 156 SVASKGQKCLKQLFVTQNVVQQANGKMQLCEQSECVWKGCKDGVRDESFHLKSSGDINDS 215
+ A++ K +T + Q N + E G ++G + + H K D
Sbjct: 110 AAATEASAMAKAATMTPAAISQQNPP----KNREATVNGEENGAHEINNHSKPMEIDGDV 165
Query: 216 ILQPEVKIHITGLRNDYYLNILDWS-FQNLVAIALG-SAVYIWN-GENHNGIENIDLSLT 272
+ P + G ++ + I W+ +L+A G S IWN EN NG +
Sbjct: 166 EIPPNKATVLRGHESEVF--ICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRH 223
Query: 273 C-----------NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLG-HLSVVGA 320
C ++S+ W +GT LA+G+ +G ++W L + LG H + A
Sbjct: 224 CIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFA 281
Query: 321 LSWN---HFILSSG---------SRLGRV-----YH------------------------ 339
L WN +++LS+G + G +H
Sbjct: 282 LKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCI 341
Query: 340 HDVRVA-QHHVGTLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKV 397
H R+ H V T + H V A+KW P G LL+S D L IW A
Sbjct: 342 HVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHD----- 396
Query: 398 ITQSTAVKICSLIWLP-------KTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRV 450
Q+ + +I ++ W P I + + V +W + H+ V
Sbjct: 397 -LQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPV 455
Query: 451 LHLALSPDQTRVFSAAADGTASVWN 475
+A SPD + S + D +WN
Sbjct: 456 YSVAFSPDGKYLASGSFDKYVHIWN 480
Score = 43.5 bits (101), Expect = 4e-04
Identities = 27/126 (21%), Positives = 56/126 (44%), Gaps = 11/126 (8%)
Query: 274 NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--------- 324
N ++++ W G LA + + +++W + + ++ H + + W+
Sbjct: 360 NEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNP 419
Query: 325 --HFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIW 382
+L+S S V DV ++H++ V ++ +SPDG+ L+SG D + IW
Sbjct: 420 NSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIW 479
Query: 383 PHDPGA 388
G+
Sbjct: 480 NTQSGS 485
Score = 33.9 bits (76), Expect = 0.33
Identities = 34/146 (23%), Positives = 54/146 (36%), Gaps = 12/146 (8%)
Query: 341 DVRVAQHHVGTLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIW---PHDPGASAQGQPLK 396
DV + + LR H+ V W+P LL+SG D IW + G S Q
Sbjct: 164 DVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRH 223
Query: 397 VITQS-----TAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVL 451
I + + + SL W + G+ +WT + + H+G +
Sbjct: 224 CIREGGHDVPSNKDVTSLDW--NSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIF 280
Query: 452 HLALSPDQTRVFSAAADGTASVWNCY 477
L + V SA D T +W+ +
Sbjct: 281 ALKWNKKGNYVLSAGVDKTTIIWDAH 306
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 57.0 bits (136), Expect = 4e-08
Identities = 86/385 (22%), Positives = 140/385 (36%), Gaps = 79/385 (20%)
Query: 156 SVASKGQKCLKQLFVTQNVVQQANGKMQLCEQSECVWKGCKDGVRDESFHLKSSGDINDS 215
+ A++ K +T + Q N + E G ++G + + H K D
Sbjct: 110 AAATEASAMAKAATMTPAAISQQNPP----KNREATVNGEENGAHEINNHSKPMEIDGDV 165
Query: 216 ILQPEVKIHITGLRNDYYLNILDWS-FQNLVAIALG-SAVYIWN-GENHNGIENIDLSLT 272
+ P + G ++ + I W+ +L+A G S IWN EN NG +
Sbjct: 166 EIPPNKATVLRGHESEVF--ICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRH 223
Query: 273 C-----------NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLG-HLSVVGA 320
C ++S+ W +GT LA+G+ +G ++W L + LG H + A
Sbjct: 224 CIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFA 281
Query: 321 LSWN---HFILSSG---------SRLGRV-----YH------------------------ 339
L WN +++LS+G + G +H
Sbjct: 282 LKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCI 341
Query: 340 HDVRVA-QHHVGTLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKV 397
H R+ H V T + H V A+KW P G LL+S D L IW A
Sbjct: 342 HVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHD----- 396
Query: 398 ITQSTAVKICSLIWLP-------KTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRV 450
Q+ + +I ++ W P I + + V +W + H+ V
Sbjct: 397 -LQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPV 455
Query: 451 LHLALSPDQTRVFSAAADGTASVWN 475
+A SPD + S + D +WN
Sbjct: 456 YSVAFSPDGKYLASGSFDKYVHIWN 480
Score = 43.5 bits (101), Expect = 4e-04
Identities = 27/126 (21%), Positives = 56/126 (44%), Gaps = 11/126 (8%)
Query: 274 NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--------- 324
N ++++ W G LA + + +++W + + ++ H + + W+
Sbjct: 360 NEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNP 419
Query: 325 --HFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIW 382
+L+S S V DV ++H++ V ++ +SPDG+ L+SG D + IW
Sbjct: 420 NSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIW 479
Query: 383 PHDPGA 388
G+
Sbjct: 480 NTQSGS 485
Score = 33.9 bits (76), Expect = 0.33
Identities = 34/146 (23%), Positives = 54/146 (36%), Gaps = 12/146 (8%)
Query: 341 DVRVAQHHVGTLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIW---PHDPGASAQGQPLK 396
DV + + LR H+ V W+P LL+SG D IW + G S Q
Sbjct: 164 DVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRH 223
Query: 397 VITQS-----TAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVL 451
I + + + SL W + G+ +WT + + H+G +
Sbjct: 224 CIREGGHDVPSNKDVTSLDW--NSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIF 280
Query: 452 HLALSPDQTRVFSAAADGTASVWNCY 477
L + V SA D T +W+ +
Sbjct: 281 ALKWNKKGNYVLSAGVDKTTIIWDAH 306
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 57.0 bits (136), Expect = 4e-08
Identities = 86/385 (22%), Positives = 140/385 (36%), Gaps = 79/385 (20%)
Query: 156 SVASKGQKCLKQLFVTQNVVQQANGKMQLCEQSECVWKGCKDGVRDESFHLKSSGDINDS 215
+ A++ K +T + Q N + E G ++G + + H K D
Sbjct: 110 AAATEASAMAKAATMTPAAISQQNPP----KNREATVNGEENGAHEINNHSKPMEIDGDV 165
Query: 216 ILQPEVKIHITGLRNDYYLNILDWS-FQNLVAIALG-SAVYIWN-GENHNGIENIDLSLT 272
+ P + G ++ + I W+ +L+A G S IWN EN NG +
Sbjct: 166 EIPPNKATVLRGHESEVF--ICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRH 223
Query: 273 C-----------NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLG-HLSVVGA 320
C ++S+ W +GT LA+G+ +G ++W L + LG H + A
Sbjct: 224 CIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW--TENGNLASTLGQHKGPIFA 281
Query: 321 LSWN---HFILSSG---------SRLGRV-----YH------------------------ 339
L WN +++LS+G + G +H
Sbjct: 282 LKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCI 341
Query: 340 HDVRVA-QHHVGTLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKV 397
H R+ H V T + H V A+KW P G LL+S D L IW A
Sbjct: 342 HVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHD----- 396
Query: 398 ITQSTAVKICSLIWLP-------KTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRV 450
Q+ + +I ++ W P I + + V +W + H+ V
Sbjct: 397 -LQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPV 455
Query: 451 LHLALSPDQTRVFSAAADGTASVWN 475
+A SPD + S + D +WN
Sbjct: 456 YSVAFSPDGKYLASGSFDKYVHIWN 480
Score = 43.5 bits (101), Expect = 4e-04
Identities = 27/126 (21%), Positives = 56/126 (44%), Gaps = 11/126 (8%)
Query: 274 NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--------- 324
N ++++ W G LA + + +++W + + ++ H + + W+
Sbjct: 360 NEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNP 419
Query: 325 --HFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIW 382
+L+S S V DV ++H++ V ++ +SPDG+ L+SG D + IW
Sbjct: 420 NSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIW 479
Query: 383 PHDPGA 388
G+
Sbjct: 480 NTQSGS 485
Score = 33.9 bits (76), Expect = 0.33
Identities = 34/146 (23%), Positives = 54/146 (36%), Gaps = 12/146 (8%)
Query: 341 DVRVAQHHVGTLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIW---PHDPGASAQGQPLK 396
DV + + LR H+ V W+P LL+SG D IW + G S Q
Sbjct: 164 DVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRH 223
Query: 397 VITQS-----TAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVL 451
I + + + SL W + G+ +WT + + H+G +
Sbjct: 224 CIREGGHDVPSNKDVTSLDW--NSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIF 280
Query: 452 HLALSPDQTRVFSAAADGTASVWNCY 477
L + V SA D T +W+ +
Sbjct: 281 ALKWNKKGNYVLSAGVDKTTIIWDAH 306
>gi|62234438 Notchless gene homolog isoform b [Homo sapiens]
Length = 193
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/109 (30%), Positives = 57/109 (52%), Gaps = 2/109 (1%)
Query: 276 ISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--HFILSSGSR 333
I+ V + + +A + + ++LWD T K L ++ GH++ V ++W+ +L SGS
Sbjct: 83 INQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSS 142
Query: 334 LGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIW 382
+ DV+ + + H V A+ WSPDG+ ++SG D L IW
Sbjct: 143 DSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 191
Score = 36.2 bits (82), Expect = 0.067
Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 14/124 (11%)
Query: 354 HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPG---ASAQGQPLKVITQSTAVKICSLI 410
H+ + + +SPD R+++S D + +W G AS +G + +
Sbjct: 79 HQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGH---------VAAVYQIA 129
Query: 411 WLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGT 470
W ++ + +G + + VW + GH V + SPD RV S D
Sbjct: 130 WSADSRLLVSGSSD--STLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKC 187
Query: 471 ASVW 474
+W
Sbjct: 188 LRIW 191
Score = 32.0 bits (71), Expect = 1.3
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 7/106 (6%)
Query: 370 LSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDV 429
L SG D L +W + +PL +T A+ I +++ P ++ +A+ +
Sbjct: 52 LVSGSDDFTLFLW----SPAEDKKPLTRMTGHQAL-INQVLFSPDSRIVASASFD--KSI 104
Query: 430 TVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
+W T GH V +A S D + S ++D T VW+
Sbjct: 105 KLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWD 150
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/214 (21%), Positives = 89/214 (41%), Gaps = 33/214 (15%)
Query: 276 ISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFI---LSSGS 332
+++V+ K G+C G+ + +LWD + + L + GH +VV A+++N+ +++GS
Sbjct: 95 LTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGS 154
Query: 333 ----------RLGRVYHHDVRVAQHHVGTLR-HKQAVCALKWSPDGRLLSSGCSDGLLTI 381
G+ YH T R H + L ++P L+++G D +
Sbjct: 155 FDKTCKLWSVETGKCYH-----------TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKL 203
Query: 382 WPHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSG 441
W G + + +I SL + I T G+ + V VW T +
Sbjct: 204 WDIQNGEEV------YTLRGHSAEIISLSFNTSGDRIIT--GSFDHTVVVWDADTGRKVN 255
Query: 442 GFFGHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
GH + + + D + + + + D T +W+
Sbjct: 256 ILIGHCAEISSASFNWDCSLILTGSMDKTCKLWD 289
Score = 45.4 bits (106), Expect = 1e-04
Identities = 42/207 (20%), Positives = 89/207 (42%), Gaps = 20/207 (9%)
Query: 276 ISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRL- 334
I +S+ + T +A G+ + +LWD+ + + + GH + + +LS+N +SG R+
Sbjct: 180 IVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFN----TSGDRII 235
Query: 335 GRVYHHDVRVAQHHVGT-----LRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGAS 389
+ H V V G + H + + ++ D L+ +G D +W +
Sbjct: 236 TGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWD-----A 290
Query: 390 AQGQPLKVITQSTAVKICSLI-WLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRG 448
G+ + +T + S + K A+ GT + +++ T GH G
Sbjct: 291 TNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTAR----IFSAATRKCIAKLEGHEG 346
Query: 449 RVLHLALSPDQTRVFSAAADGTASVWN 475
+ ++ +P + + ++D TA +W+
Sbjct: 347 EISKISFNPQGNHLLTGSSDKTARIWD 373
Score = 39.3 bits (90), Expect = 0.008
Identities = 41/215 (19%), Positives = 82/215 (38%), Gaps = 10/215 (4%)
Query: 262 NGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGAL 321
NG E L I S+S+ G + G+ + V +WD T +++ ++GH + + +
Sbjct: 208 NGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSA 267
Query: 322 S--WNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLL 379
S W+ ++ +GS D + H + + G+L+++ +DG
Sbjct: 268 SFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTA 327
Query: 380 TIWPHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSR 439
I+ SA + + +I + + P+ + T G+ +W T
Sbjct: 328 RIF------SAATRKCIAKLEGHEGEISKISFNPQGNHLLT--GSSDKTARIWDAQTGQC 379
Query: 440 SGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVW 474
GH + A + V + + D T +W
Sbjct: 380 LQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 4/98 (4%)
Query: 288 LAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSW--NHFILSSGSRLGRVYHHDVRVA 345
+A G+++ V+LWDV+ +R GH + +L++ N L++G+ GRV D+
Sbjct: 642 VATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG 701
Query: 346 QHHVGTLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIW 382
VG L+ H VC+L++S DG +L+SG D + +W
Sbjct: 702 LM-VGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/181 (25%), Positives = 76/181 (41%), Gaps = 12/181 (6%)
Query: 298 QLWDVVTKKRLRNMLGHLSVVGALSWN---HFILSSGSRLGRVYHHDVRVAQHHVGTLRH 354
++ D T L+ + GH V S++ +++LSS S G V ++ VG H
Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSS-SEDGTVRLWSLQTFTCLVGYKGH 584
Query: 355 KQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLPK 414
V ++SP G SG D + +W D QPL++ A C+ P
Sbjct: 585 NYPVWDTQFSPYGYYFVSGGHDRVARLWATD-----HYQPLRIFAGHLADVNCTRFH-PN 638
Query: 415 TKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVW 474
+ +ATG V +W + F GH+G + L SP+ + + A DG +W
Sbjct: 639 SNYVATGSAD--RTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLW 696
Query: 475 N 475
+
Sbjct: 697 D 697
Score = 40.4 bits (93), Expect = 0.004
Identities = 46/208 (22%), Positives = 81/208 (38%), Gaps = 22/208 (10%)
Query: 276 ISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN----HFILSSG 331
+ S+ + L + +G V+LW + T L GH V ++ +F+
Sbjct: 546 VYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGH 605
Query: 332 SRLGRVYHHDVRVAQHHVGTLR----HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPG 387
R+ R++ D H LR H V ++ P+ +++G +D + +W
Sbjct: 606 DRVARLWATD------HYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD---- 655
Query: 388 ASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHR 447
G +++ T I SL + P + +ATG + V +W G GH
Sbjct: 656 -VLNGNCVRIFTGHKG-PIHSLTFSPNGRFLATGATDGR--VLLWDIGHGLMVGELKGHT 711
Query: 448 GRVLHLALSPDQTRVFSAAADGTASVWN 475
V L S D + S + D T +W+
Sbjct: 712 DTVCSLRFSRDGEILASGSMDNTVRLWD 739
Score = 35.0 bits (79), Expect = 0.15
Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 23/122 (18%)
Query: 356 QAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIWLPKT 415
Q + A+ + D L++ G +D + +W P + L+ + Q++ + +
Sbjct: 471 QGLTAVDVTDDSSLIAGGFADSTVRVWSVTP------KKLRSVKQASDLSLID------- 517
Query: 416 KEIATGQGTPKNDVT--VWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASV 473
KE +DV + T S +GH G V + SPD+ + S++ DGT +
Sbjct: 518 KE--------SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRL 569
Query: 474 WN 475
W+
Sbjct: 570 WS 571
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 54.3 bits (129), Expect = 2e-07
Identities = 63/285 (22%), Positives = 111/285 (38%), Gaps = 40/285 (14%)
Query: 199 VRDESFHLKSSGDINDSILQPEVKIHITGLRNDYYLNILDWSFQNLVAIALGSAVYIWNG 258
VR F + G++N S P+ ++ +TG + + W + S +W
Sbjct: 11 VRRVKFFGQHGGEVNSSAFSPDGQMLLTGSEDGC---VYGWETR--------SGQLLWRL 59
Query: 259 ENHNGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVV 318
H G + + +G A + + V+LWDV K LR + GH V
Sbjct: 60 GGHTGP-----------VKFCRFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSV 108
Query: 319 GALSWNHFI--LSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSD 376
+S++ L+SG RV DV+ Q + H+ ++ + +SP L++G D
Sbjct: 109 ETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWD 168
Query: 377 GLLTIWPHDPGASAQGQPLKVITQSTAVKI-----CSLIWLPKTKEIATGQGTPKNDVTV 431
+ IW L+++T + + + ++ L + G+ + +
Sbjct: 169 STVHIWD-----------LRMVTPAVSHQALEGHSANISCLCYSASGLLASGSWDKTIHI 217
Query: 432 WTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWNC 476
W T S GH V +A SPD+ + SA VW+C
Sbjct: 218 WKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDC 262
Score = 45.1 bits (105), Expect = 1e-04
Identities = 53/200 (26%), Positives = 85/200 (42%), Gaps = 14/200 (7%)
Query: 276 ISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFI--LSSGSR 333
+ +VS+ + LA G + V LWDV + + LR ++GH + + ++ + L++GS
Sbjct: 108 VETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSW 167
Query: 334 LGRVYHHDVRV---AQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASA 390
V+ D+R+ A H H + L +S G LL+SG D + IW P S+
Sbjct: 168 DSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASG-LLASGSWDKTIHIW--KPTTSS 224
Query: 391 QGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRV 450
L + + + S+ + P E+ V VW C T G
Sbjct: 225 ----LLIQLKGHVTWVKSIAFSP--DELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVA 278
Query: 451 LHLALSPDQTRVFSAAADGT 470
A +PD + S AAD T
Sbjct: 279 HTCAFTPDGKILVSGAADQT 298
>gi|5729852 guanine nucleotide-binding protein, beta-5 subunit
isoform a [Homo sapiens]
Length = 353
Score = 53.9 bits (128), Expect = 3e-07
Identities = 48/212 (22%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Query: 269 LSLTCNYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGH------LSVVGALS 322
+++ NY+S+ S+ + + +G LWDV + + L++ GH L + + +
Sbjct: 149 VAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSET 208
Query: 323 WNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIW 382
N F+ + V+ D+R Q H+ + ++++ P G +SG D ++
Sbjct: 209 GNTFVSGGCDKKAMVW--DMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLY 266
Query: 383 PHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGG 442
D A + + + ++ + + S + + + G + VW SR
Sbjct: 267 --DLRADRE---VAIYSKESIIFGASSVDFSLSGRLLFA-GYNDYTINVWDVLKGSRVSI 320
Query: 443 FFGHRGRVLHLALSPDQTRVFSAAADGTASVW 474
FGH RV L +SPD T S + D T VW
Sbjct: 321 LFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
>gi|20336270 guanine nucleotide-binding protein, beta-5 subunit
isoform b [Homo sapiens]
Length = 395
Score = 53.9 bits (128), Expect = 3e-07
Identities = 48/212 (22%), Positives = 90/212 (42%), Gaps = 14/212 (6%)
Query: 269 LSLTCNYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGH------LSVVGALS 322
+++ NY+S+ S+ + + +G LWDV + + L++ GH L + + +
Sbjct: 191 VAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSET 250
Query: 323 WNHFILSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIW 382
N F+ + V+ D+R Q H+ + ++++ P G +SG D ++
Sbjct: 251 GNTFVSGGCDKKAMVW--DMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLY 308
Query: 383 PHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGG 442
D A + + + ++ + + S + + + G + VW SR
Sbjct: 309 --DLRADRE---VAIYSKESIIFGASSVDFSLSGRLLFA-GYNDYTINVWDVLKGSRVSI 362
Query: 443 FFGHRGRVLHLALSPDQTRVFSAAADGTASVW 474
FGH RV L +SPD T S + D T VW
Sbjct: 363 LFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
>gi|157739942 gemin 5 [Homo sapiens]
Length = 1508
Score = 52.4 bits (124), Expect = 9e-07
Identities = 30/129 (23%), Positives = 61/129 (47%), Gaps = 24/129 (18%)
Query: 277 SSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNH---------FI 327
+ +SW +G +A+G +G ++++ + K + + H +V +SW+H ++
Sbjct: 540 TEISWKADGKIMALGNEDGSIEIFQIPNLKLICTIQQHHKLVNTISWHHEHGSQPELSYL 599
Query: 328 LSSGSRLGRVYHHD------------VRVAQHHVGTLRHKQAVCALKWSP--DGRLLSSG 373
++SGS +Y H+ V + + + H + ++ WSP DGRL+S+
Sbjct: 600 MASGSNNAVIYVHNLKTVIESSPESPVTITEPYRTLSGHTAKITSVAWSPHHDGRLVSAS 659
Query: 374 CSDGLLTIW 382
DG +W
Sbjct: 660 -YDGTAQVW 667
Score = 50.8 bits (120), Expect = 3e-06
Identities = 68/288 (23%), Positives = 118/288 (40%), Gaps = 71/288 (24%)
Query: 245 VAIALGSA-VYIWNG---ENHNGIENIDLSLTCNYISSVSW--IKEGTCLAVGTSEGEVQ 298
+AI +G + +WN +N+ ++N + ++++ W KEG CLA GT +G+V
Sbjct: 395 LAIGVGDGMIRVWNTLSIKNNYDVKNFWQGVKSK-VTALCWHPTKEG-CLAFGTDDGKVG 452
Query: 299 LWDVVTKKRLR-NMLGHLSVVGALSWN---------------HFILSSGSRLGRVYHH-- 340
L+D + K + + H V L+W L S G V H
Sbjct: 453 LYDTYSNKPPQISSTYHKKTVYTLAWGPPVPPMSLGGEGDRPSLALYSCGGEGIVLQHNP 512
Query: 341 --------DVRVAQHHVGTLRHKQAV-CALKWSPDGRLLSSGCSDGLLTI---------- 381
D+ ++++K V + W DG++++ G DG + I
Sbjct: 513 WKLSGEAFDINKLIRDTNSIKYKLPVHTEISWKADGKIMALGNEDGSIEIFQIPNLKLIC 572
Query: 382 -------------WPHDPGASAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKND 428
W H+ G+ + L + AV I++ K + + +P++
Sbjct: 573 TIQQHHKLVNTISWHHEHGSQPELSYLMASGSNNAV-----IYVHNLKTVI--ESSPESP 625
Query: 429 VTVWTCPTVSRSGGFFGHRGRVLHLALSPDQT-RVFSAAADGTASVWN 475
VT+ T P + S GH ++ +A SP R+ SA+ DGTA VW+
Sbjct: 626 VTI-TEPYRTLS----GHTAKITSVAWSPHHDGRLVSASYDGTAQVWD 668
Score = 30.0 bits (66), Expect = 4.8
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 9/99 (9%)
Query: 289 AVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN---HFILSSGSRLGRV--YHHDVR 343
A + +G V++WDV TK + H + L W+ ++ SG G V Y +
Sbjct: 83 ATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPRVKDLIVSGDEKGVVFCYWFNRN 142
Query: 344 VAQHHVGTLRHKQAVCALKWSPDGR-LLSSGCSDGLLTI 381
+QH + + L SP L++ G DG++ I
Sbjct: 143 DSQH---LFIEPRTIFCLTCSPHHEDLVAIGYKDGIVVI 178
Score = 29.3 bits (64), Expect = 8.2
Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 276 ISSVSWIKEGTCLAVGTS-EGEVQLWDVVTKKRLRNMLGHLSVVGALSWN 324
I+SV+W V S +G Q+WD + ++ L N GH + ++W+
Sbjct: 642 ITSVAWSPHHDGRLVSASYDGTAQVWDALREEPLCNFRGHRGRLLCVAWS 691
>gi|20357529 guanine nucleotide-binding protein, beta-2 subunit
[Homo sapiens]
Length = 340
Score = 52.4 bits (124), Expect = 9e-07
Identities = 64/278 (23%), Positives = 100/278 (35%), Gaps = 53/278 (19%)
Query: 244 LVAIALGSAVYIWNGENHNGIENIDLS----LTCNYISSVSWIKEG------TCLAVGTS 293
LV+ + + IW+ N + I L +TC Y S +++ G + ++ T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTR 129
Query: 294 EGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLR 353
EG V++ + L G+LS L N I SSG ++ D+ Q VG
Sbjct: 130 EGNVRV-----SRELPGHTGYLSCCRFLDDNQIITSSGDTTCALW--DIETGQQTVGFAG 182
Query: 354 HKQAVCALKWSPDGRLLSSGCSDGLLTIWP--------------HDPGASAQGQPLKVIT 399
H V +L +PDGR SG D + +W D A A T
Sbjct: 183 HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFT 242
Query: 400 QSTAVKICSLIWLPKTKEIA------------------TGQ----GTPKNDVTVWTCPTV 437
+ C L L +E+ +G+ G + +W
Sbjct: 243 TGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
Query: 438 SRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
R+G GH RV L ++ D V + + D +WN
Sbjct: 303 DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
Score = 48.5 bits (114), Expect = 1e-05
Identities = 46/163 (28%), Positives = 64/163 (39%), Gaps = 38/163 (23%)
Query: 351 TLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLK---VITQSTAVK- 405
TLR H + A+ W D RLL S DG L IW PL+ V+T + A
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 406 ----------ICSLIWLPK-------TKEIATGQG--------------TPKNDVT--VW 432
ICS+ L ++E+ G T D T +W
Sbjct: 110 NFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALW 169
Query: 433 TCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
T ++ GF GH G V+ L+L+PD S A D + +W+
Sbjct: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
[Homo sapiens]
Length = 340
Score = 49.3 bits (116), Expect = 8e-06
Identities = 47/163 (28%), Positives = 65/163 (39%), Gaps = 38/163 (23%)
Query: 351 TLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLK---VITQSTAVK- 405
TLR H + A+ W D RLL S DG L IW PL+ V+T + A
Sbjct: 50 TLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSG 109
Query: 406 ----------ICSLIWLPK-------TKEIATGQG--------------TPKNDVT--VW 432
ICS+ L ++E+A G T D T +W
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW 169
Query: 433 TCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
T ++ F GH G V+ L+L+PD S A D +A +W+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Score = 46.6 bits (109), Expect = 5e-05
Identities = 61/278 (21%), Positives = 94/278 (33%), Gaps = 53/278 (19%)
Query: 244 LVAIALGSAVYIWNGENHNGIENIDLS----LTCNYISSVSWIKEG------TCLAVGTS 293
LV+ + + IW+ N + I L +TC Y S +++ G + + T
Sbjct: 70 LVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTR 129
Query: 294 EGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRVAQHHVGTLR 353
EG V++ + L G+LS L N + SSG ++ D+ Q
Sbjct: 130 EGNVRV-----SRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALW--DIETGQQTTTFTG 182
Query: 354 HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQ---GQPLKV-----------IT 399
H V +L +PD RL SG D +W G Q G +
Sbjct: 183 HTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFA 242
Query: 400 QSTAVKICSLIWLPKTKEIATGQ----------------------GTPKNDVTVWTCPTV 437
+ C L L +E+ T G + VW
Sbjct: 243 TGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA 302
Query: 438 SRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
R+G GH RV L ++ D V + + D +WN
Sbjct: 303 DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit
[Homo sapiens]
Length = 340
Score = 48.1 bits (113), Expect = 2e-05
Identities = 46/163 (28%), Positives = 64/163 (39%), Gaps = 38/163 (23%)
Query: 351 TLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLK---VITQSTAVK- 405
TLR H + A+ W D RLL S DG L IW PL+ V+T + A
Sbjct: 50 TLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSG 109
Query: 406 ----------ICSLIWLPK-------TKEIATGQG--------------TPKNDVT--VW 432
ICS+ L ++E+ G T D T +W
Sbjct: 110 NYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALW 169
Query: 433 TCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
T ++ F GH G V+ L+LSPD S A D ++ +W+
Sbjct: 170 DIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWD 212
Score = 42.0 bits (97), Expect = 0.001
Identities = 64/288 (22%), Positives = 101/288 (35%), Gaps = 57/288 (19%)
Query: 237 LDWSFQN--LVAIALGSAVYIWNGENHNGIENIDLS----LTCNYISSVSWIKEG----- 285
+ W + + LV+ + + IW+ N + I L +TC Y S +++ G
Sbjct: 61 MHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNI 120
Query: 286 -TCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVRV 344
+ + T EG V++ + L G+LS L + + SSG ++ D+
Sbjct: 121 CSIYNLKTREGNVRV-----SRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALW--DIET 173
Query: 345 AQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAV 404
AQ H V +L SPD R SG D +W G Q V + AV
Sbjct: 174 AQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHV-SDINAV 232
Query: 405 KI---------------CSLIWLPKTKEIA------------------TGQ----GTPKN 427
C L L +E+ +G+ G
Sbjct: 233 SFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDF 292
Query: 428 DVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
+ VW R+G GH RV L ++ D V + + D +WN
Sbjct: 293 NCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 47.8 bits (112), Expect = 2e-05
Identities = 51/208 (24%), Positives = 89/208 (42%), Gaps = 16/208 (7%)
Query: 276 ISSVSWIKEG-TCLAVGTSEGEVQLWDVVTKKRLRNMLGH-LSVVGALSWNHFILSSGSR 333
I S+SW G C+A GTS +W+V K ++ H + + ++W+H R
Sbjct: 415 IYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSH---KDSKR 471
Query: 334 LGRVYHHDVRVAQHHVGTLRHK----QAVCALKWSPDGR-LLSSGCSDGLLTIWPHDPGA 388
+ + + G + HK AV WS + + ++++GC D + ++ A
Sbjct: 472 IATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY---YVA 528
Query: 389 SAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRG 448
++ QPLKV + TA K+ + W P + I G+ V +W + GH
Sbjct: 529 TSSDQPLKVFSGHTA-KVFHVKWSPLREGILC-SGSDDGTVRIWDYTQDACINILNGHTA 586
Query: 449 RVLHLALSPD-QTRVFSAAADGTASVWN 475
V L + + + S + D T VW+
Sbjct: 587 PVRGLMWNTEIPYLLISGSWDYTIKVWD 614
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/197 (24%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 288 LAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSW---NHFILSSGSRLGRVYHHDVRV 344
LA + +G +++WD+ T + G+ V+ +LSW ++ G+ + +V+
Sbjct: 385 LATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQK 444
Query: 345 AQHHVGTLRH-KQAVCALKWS-PDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQST 402
+ H + + WS D + +++ SDG I + G+ L
Sbjct: 445 GKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCII------RTIDGKVLHKYKHPA 498
Query: 403 AVKICSLIWLPKTKE-IATGQGTPKNDVTVWTCPTVSRS--GGFFGHRGRVLHLALSPDQ 459
AV C W K+ IAT G +V V+ T S F GH +V H+ SP +
Sbjct: 499 AVFGCD--WSQNNKDMIAT--GCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLR 554
Query: 460 TRVF-SAAADGTASVWN 475
+ S + DGT +W+
Sbjct: 555 EGILCSGSDDGTVRIWD 571
Score = 35.4 bits (80), Expect = 0.11
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 17/115 (14%)
Query: 279 VSW--IKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN---HFILSSGSR 333
V W ++EG L G+ +G V++WD + + GH + V L WN ++L SGS
Sbjct: 548 VKWSPLREGI-LCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGS- 605
Query: 334 LGRVYHHDVRVAQHHVGT-----LRHKQAVCALKWSPDGRLLSSGCS-DGLLTIW 382
+ + ++V GT H V L P + CS D + +W
Sbjct: 606 ----WDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 656
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 47.8 bits (112), Expect = 2e-05
Identities = 51/208 (24%), Positives = 89/208 (42%), Gaps = 16/208 (7%)
Query: 276 ISSVSWIKEG-TCLAVGTSEGEVQLWDVVTKKRLRNMLGH-LSVVGALSWNHFILSSGSR 333
I S+SW G C+A GTS +W+V K ++ H + + ++W+H R
Sbjct: 439 IYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAWSH---KDSKR 495
Query: 334 LGRVYHHDVRVAQHHVGTLRHK----QAVCALKWSPDGR-LLSSGCSDGLLTIWPHDPGA 388
+ + + G + HK AV WS + + ++++GC D + ++ A
Sbjct: 496 IATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRVY---YVA 552
Query: 389 SAQGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRG 448
++ QPLKV + TA K+ + W P + I G+ V +W + GH
Sbjct: 553 TSSDQPLKVFSGHTA-KVFHVKWSPLREGILC-SGSDDGTVRIWDYTQDACINILNGHTA 610
Query: 449 RVLHLALSPD-QTRVFSAAADGTASVWN 475
V L + + + S + D T VW+
Sbjct: 611 PVRGLMWNTEIPYLLISGSWDYTIKVWD 638
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/197 (24%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 288 LAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSW---NHFILSSGSRLGRVYHHDVRV 344
LA + +G +++WD+ T + G+ V+ +LSW ++ G+ + +V+
Sbjct: 409 LATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQK 468
Query: 345 AQHHVGTLRH-KQAVCALKWS-PDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQST 402
+ H + + WS D + +++ SDG I + G+ L
Sbjct: 469 GKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCII------RTIDGKVLHKYKHPA 522
Query: 403 AVKICSLIWLPKTKE-IATGQGTPKNDVTVWTCPTVSRS--GGFFGHRGRVLHLALSPDQ 459
AV C W K+ IAT G +V V+ T S F GH +V H+ SP +
Sbjct: 523 AVFGCD--WSQNNKDMIAT--GCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLR 578
Query: 460 TRVF-SAAADGTASVWN 475
+ S + DGT +W+
Sbjct: 579 EGILCSGSDDGTVRIWD 595
Score = 35.4 bits (80), Expect = 0.11
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 17/115 (14%)
Query: 279 VSW--IKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN---HFILSSGSR 333
V W ++EG L G+ +G V++WD + + GH + V L WN ++L SGS
Sbjct: 572 VKWSPLREGI-LCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGS- 629
Query: 334 LGRVYHHDVRVAQHHVGT-----LRHKQAVCALKWSPDGRLLSSGCS-DGLLTIW 382
+ + ++V GT H V L P + CS D + +W
Sbjct: 630 ----WDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 680
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 47.8 bits (112), Expect = 2e-05
Identities = 53/233 (22%), Positives = 97/233 (41%), Gaps = 16/233 (6%)
Query: 244 LVAIALGSAVYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTCLA-VGTSEGEVQLWDV 302
L + + V +W+ E ++ L ++++S + G L G+ +G V+LWD+
Sbjct: 124 LFSASTDKTVAVWDSETGERVKR--LKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI 181
Query: 303 VTKKRLRNMLGHLSVVGALSWNHFI--LSSGSRLGRVYHHDVRVAQHHVGTLRHKQAVCA 360
K ++ V+ A+++N + SG + D+R + H +V
Sbjct: 182 RKKAAIQTFQNTYQVL-AVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTG 240
Query: 361 LKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVI---TQSTAVKICSLIWLPKTKE 417
L S +G L S D + +W P A + + +K+ + + W P +
Sbjct: 241 LSLSSEGSYLLSNAMDNTVRVWDVRPFAPKE-RCVKIFQGNVHNFEKNLLRCSWSPDGSK 299
Query: 418 IATGQGTPKNDVTVWTCPTVSRSGGFF--GHRGRVLHLALSPDQTRVFSAAAD 468
IA G D V+ T SR + GH G + +A PD+ + SA++D
Sbjct: 300 IAAGSA----DRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
Score = 37.0 bits (84), Expect = 0.039
Identities = 40/192 (20%), Positives = 70/192 (36%), Gaps = 48/192 (25%)
Query: 284 EGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVYHHDVR 343
+G+ L +++ V +WD T +R++ + GH S V +
Sbjct: 120 DGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSC---------------------- 157
Query: 344 VAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTA 403
R Q VC +G DG + +W A+ Q T
Sbjct: 158 -----YPARRGPQLVC------------TGSDDGTVKLWDIRKKAAIQ-------TFQNT 193
Query: 404 VKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVF 463
++ ++ + + +I +G ND+ VW + GH V L+LS + + +
Sbjct: 194 YQVLAVTFNDTSDQIISGG--IDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLL 251
Query: 464 SAAADGTASVWN 475
S A D T VW+
Sbjct: 252 SNAMDNTVRVWD 263
Score = 35.8 bits (81), Expect = 0.088
Identities = 24/93 (25%), Positives = 48/93 (51%), Gaps = 11/93 (11%)
Query: 253 VYIWNGENHNGIENIDLSLTCNYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNML 312
V I+ G HN +N+ L C SW +G+ +A G+++ V +WD +++ L +
Sbjct: 274 VKIFQGNVHNFEKNL---LRC------SWSPDGSKIAAGSADRFVYVWDTTSRRILYKLP 324
Query: 313 GHLSVVGALSW--NHFILSSGSRLGRVYHHDVR 343
GH + +++ + I+ S S R+Y +++
Sbjct: 325 GHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
Score = 32.0 bits (71), Expect = 1.3
Identities = 13/31 (41%), Positives = 20/31 (64%)
Query: 445 GHRGRVLHLALSPDQTRVFSAAADGTASVWN 475
GH G V+ L + D + +FSA+ D T +VW+
Sbjct: 107 GHSGAVMELHYNTDGSMLFSASTDKTVAVWD 137
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 47.8 bits (112), Expect = 2e-05
Identities = 42/198 (21%), Positives = 78/198 (39%), Gaps = 21/198 (10%)
Query: 279 VSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWNHFILSSGSRLGRVY 338
V W EG L G S GE LW+ +T + H S V A++W+H + L +
Sbjct: 125 VRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSH---NDMWMLTADH 181
Query: 339 HHDVRVAQHHVGTLR----HKQAVCALKWSPDGRLLSSGCSDGLLTIWP----HDPGASA 390
V+ Q ++ ++ HK+A+ +SP ++ DG + IW H+
Sbjct: 182 GGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHE----- 236
Query: 391 QGQPLKVITQSTAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRV 450
+ I + + + W P + +G + + W T H+ V
Sbjct: 237 -----ERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTV 291
Query: 451 LHLALSPDQTRVFSAAAD 468
+ + L+ + + +A+ D
Sbjct: 292 MEVKLNLNGNWLLTASRD 309
Score = 36.6 bits (83), Expect = 0.051
Identities = 27/125 (21%), Positives = 51/125 (40%), Gaps = 9/125 (7%)
Query: 351 TLRHKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLI 410
T + K V ++W+P+GR L +G S G T+W + + I Q+ + ++
Sbjct: 115 TNKVKCPVFVVRWTPEGRRLVTGASSGEFTLW------NGLTFNFETILQAHDSPVRAMT 168
Query: 411 WLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRVLHLALSPDQTRVFSAAADGT 470
W + T V W ++ F H+ + + SP + + + DGT
Sbjct: 169 WSHNDMWMLTAD--HGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGT 225
Query: 471 ASVWN 475
+W+
Sbjct: 226 VRIWD 230
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 47.0 bits (110), Expect = 4e-05
Identities = 63/257 (24%), Positives = 94/257 (36%), Gaps = 71/257 (27%)
Query: 276 ISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLG-HLSVVGALSWN---HFILSSG 331
++S+ W EGT LA G+ +G ++W L + LG H + AL WN +FILS+G
Sbjct: 228 VTSLDWNSEGTLLATGSYDGFARIW--TKDGNLASTLGQHKGPIFALKWNKKGNFILSAG 285
Query: 332 ---------SRLGRV-----YH------------------------HDVRVAQHH-VGTL 352
+ G +H H ++ Q + T
Sbjct: 286 VDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTF 345
Query: 353 R-HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVITQSTAVKICSLIW 411
+ H V A+KW P G LL+S D L IW S + Q+ +I ++ W
Sbjct: 346 QGHTNEVNAIKWDPTGNLLASCSDDMTLKIW------SMKQDNCVHDLQAHNKEIYTIKW 399
Query: 412 LPKTKEIATGQGTPK-------------NDVTVWTCPTVSRSGGFFGHRGRVLHLALSPD 458
P TG GT + V +W H+ V +A SPD
Sbjct: 400 SP------TGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPD 453
Query: 459 QTRVFSAAADGTASVWN 475
+ S + D +WN
Sbjct: 454 GRYLASGSFDKCVHIWN 470
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/128 (22%), Positives = 60/128 (46%), Gaps = 15/128 (11%)
Query: 274 NYISSVSWIKEGTCLAVGTSEGEVQLWDVVTKKRLRNMLGHLSVVGALSWN--------- 324
N ++++ W G LA + + +++W + + ++ H + + W+
Sbjct: 350 NEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNP 409
Query: 325 --HFILSSGS--RLGRVYHHDVRVAQHHVGTLRHKQAVCALKWSPDGRLLSSGCSDGLLT 380
+ +L+S S R++ D + H + +H++ V ++ +SPDGR L+SG D +
Sbjct: 410 NANLMLASASFDSTVRLWDVDRGICIHTL--TKHQEPVYSVAFSPDGRYLASGSFDKCVH 467
Query: 381 IWPHDPGA 388
IW GA
Sbjct: 468 IWNTQTGA 475
Score = 33.9 bits (76), Expect = 0.33
Identities = 37/134 (27%), Positives = 59/134 (44%), Gaps = 23/134 (17%)
Query: 280 SWIKEGTCLAVGTSEGEVQLWDVV-------TKKRLRNML--GHLSV-----VGALSWNH 325
+W LA G+ + ++W++ T+ LR+ + G V V +L WN
Sbjct: 176 AWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNS 235
Query: 326 --FILSSGSRLG--RVYHHDVRVAQHHVGTL-RHKQAVCALKWSPDGRLLSSGCSDGLLT 380
+L++GS G R++ D +A TL +HK + ALKW+ G + S D
Sbjct: 236 EGTLLATGSYDGFARIWTKDGNLAS----TLGQHKGPIFALKWNKKGNFILSAGVDKTTI 291
Query: 381 IWPHDPGASAQGQP 394
IW G + Q P
Sbjct: 292 IWDAHTGEAKQQFP 305
Score = 33.5 bits (75), Expect = 0.44
Identities = 34/147 (23%), Positives = 55/147 (37%), Gaps = 14/147 (9%)
Query: 341 DVRVAQHHVGTLR-HKQAVCALKWSPDGRLLSSGCSDGLLTIWPHDPGASAQGQPLKVIT 399
DV + + LR H+ V W+P LL+SG D IW S G V+
Sbjct: 154 DVEIPPNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSEN-STSGSTQLVLR 212
Query: 400 Q---------STAVKICSLIWLPKTKEIATGQGTPKNDVTVWTCPTVSRSGGFFGHRGRV 450
+ + SL W + +AT G+ +WT + + H+G +
Sbjct: 213 HCIREGGQDVPSNKDVTSLDWNSEGTLLAT--GSYDGFARIWT-KDGNLASTLGQHKGPI 269
Query: 451 LHLALSPDQTRVFSAAADGTASVWNCY 477
L + + SA D T +W+ +
Sbjct: 270 FALKWNKKGNFILSAGVDKTTIIWDAH 296
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.129 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,854,046
Number of Sequences: 37866
Number of extensions: 829286
Number of successful extensions: 3814
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 138
Number of HSP's that attempted gapping in prelim test: 2669
Number of HSP's gapped (non-prelim): 911
length of query: 477
length of database: 18,247,518
effective HSP length: 106
effective length of query: 371
effective length of database: 14,233,722
effective search space: 5280710862
effective search space used: 5280710862
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.