Guide to the Human Genome
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Search of human proteins with 224589132

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
         (3628 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]        7376   0.0  
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...  6560   0.0  
gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap...  5979   0.0  
gi|83415174 hypothetical protein LOC400818 [Homo sapiens]            1721   0.0  
gi|92110019 hypothetical protein LOC55672 [Homo sapiens]             1702   0.0  
gi|7657017 hypothetical protein LOC25832 [Homo sapiens]              1539   0.0  
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho...  1330   0.0  
gi|156071420 hypothetical protein LOC728912 [Homo sapiens]           1328   0.0  
gi|157266285 hypothetical protein LOC728936 [Homo sapiens]           1214   0.0  
gi|29789405 hypothetical protein LOC284565 [Homo sapiens]            1211   0.0  
gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi...   823   0.0  
gi|239741297 PREDICTED: neuroblastoma breakpoint family, member ...   521   e-147
gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1...   471   e-132
gi|114158664 hypothetical protein LOC343505 [Homo sapiens]            468   e-131
gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2...   468   e-131
gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap...   468   e-131
gi|239758011 PREDICTED: hypothetical protein LOC728841, partial ...   225   7e-58
gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami...   116   5e-25
gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami...   113   3e-24
gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6...   113   3e-24
gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6...   112   9e-24
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    84   3e-15
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    71   2e-11
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     67   4e-10
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            65   9e-10
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         64   4e-09
gi|150010604 kinesin family member 4B [Homo sapiens]                   63   5e-09
gi|21735548 centrosomal protein 2 [Homo sapiens]                       63   6e-09
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    62   1e-08
gi|71061468 centromere protein E [Homo sapiens]                        62   1e-08

>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score = 7376 bits (19139), Expect = 0.0
 Identities = 3628/3628 (100%), Positives = 3628/3628 (100%)

Query: 1    MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
            MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY
Sbjct: 1    MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
            EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121  RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
            RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE
Sbjct: 121  RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181  KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
            KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL
Sbjct: 181  KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241  VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
            VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA
Sbjct: 241  VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300

Query: 301  EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
            EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA
Sbjct: 301  EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360

Query: 361  EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420
            EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA
Sbjct: 361  EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420

Query: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
Sbjct: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480

Query: 481  TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 540
            TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK
Sbjct: 481  TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 540

Query: 541  GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG 600
            GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG
Sbjct: 541  GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG 600

Query: 601  RHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAF 660
            RHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAF
Sbjct: 601  RHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAF 660

Query: 661  YILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 720
            YILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG
Sbjct: 661  YILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 720

Query: 721  YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780
            YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
Sbjct: 721  YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780

Query: 781  VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840
            VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
Sbjct: 781  VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840

Query: 841  SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY 900
            SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY
Sbjct: 841  SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY 900

Query: 901  RSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS 960
            RSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS
Sbjct: 901  RSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS 960

Query: 961  TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEV 1020
            TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEV
Sbjct: 961  TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEV 1020

Query: 1021 VEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKR 1080
            VEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKR
Sbjct: 1021 VEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKR 1080

Query: 1081 RGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDS 1140
            RGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDS
Sbjct: 1081 RGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDS 1140

Query: 1141 CQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLD 1200
            CQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLD
Sbjct: 1141 CQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLD 1200

Query: 1201 RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRE 1260
            RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRE
Sbjct: 1201 RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRE 1260

Query: 1261 LLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK 1320
            LLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK
Sbjct: 1261 LLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK 1320

Query: 1321 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 1380
            GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE
Sbjct: 1321 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 1380

Query: 1381 LTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 1440
            LTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ
Sbjct: 1381 LTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 1440

Query: 1441 DSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPC 1500
            DSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPC
Sbjct: 1441 DSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPC 1500

Query: 1501 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGE 1560
            PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGE
Sbjct: 1501 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGE 1560

Query: 1561 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST 1620
            IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST
Sbjct: 1561 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST 1620

Query: 1621 PSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK 1680
            PSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK
Sbjct: 1621 PSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK 1680

Query: 1681 EPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQ 1740
            EPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQ
Sbjct: 1681 EPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQ 1740

Query: 1741 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSL 1800
            GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSL
Sbjct: 1741 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSL 1800

Query: 1801 DVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR 1860
            DVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR
Sbjct: 1801 DVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR 1860

Query: 1861 CYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSREL 1920
            CYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSREL
Sbjct: 1861 CYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSREL 1920

Query: 1921 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEE 1980
            LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEE
Sbjct: 1921 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEE 1980

Query: 1981 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHV 2040
            EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHV
Sbjct: 1981 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHV 2040

Query: 2041 GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD 2100
            GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD
Sbjct: 2041 GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD 2100

Query: 2101 SLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRL 2160
            SLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRL
Sbjct: 2101 SLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRL 2160

Query: 2161 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 2220
            SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK
Sbjct: 2161 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 2220

Query: 2221 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2280
            DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE
Sbjct: 2221 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2280

Query: 2281 ENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 2340
            ENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE
Sbjct: 2281 ENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 2340

Query: 2341 VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPS 2400
            VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPS
Sbjct: 2341 VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPS 2400

Query: 2401 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2460
            CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD
Sbjct: 2401 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2460

Query: 2461 RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 2520
            RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF
Sbjct: 2461 RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 2520

Query: 2521 YALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 2580
            YALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE
Sbjct: 2521 YALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 2580

Query: 2581 KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEED 2640
            KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEED
Sbjct: 2581 KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEED 2640

Query: 2641 QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 2700
            QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA
Sbjct: 2641 QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 2700

Query: 2701 LDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2760
            LDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY
Sbjct: 2701 LDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2760

Query: 2761 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE 2820
            GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE
Sbjct: 2761 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE 2820

Query: 2821 LLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQE 2880
            LLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQE
Sbjct: 2821 LLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQE 2880

Query: 2881 VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 2940
            VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY
Sbjct: 2881 VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 2940

Query: 2941 LGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS 3000
            LGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS
Sbjct: 2941 LGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS 3000

Query: 3001 CQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPR 3060
            CQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPR
Sbjct: 3001 CQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPR 3060

Query: 3061 LSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIE 3120
            LSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIE
Sbjct: 3061 LSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIE 3120

Query: 3121 KYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYIL 3180
            KYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYIL
Sbjct: 3121 KYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYIL 3180

Query: 3181 EQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLE 3240
            EQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLE
Sbjct: 3181 EQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLE 3240

Query: 3241 LPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQ 3300
            LPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQ
Sbjct: 3241 LPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQ 3300

Query: 3301 DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK 3360
            DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK
Sbjct: 3301 DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK 3360

Query: 3361 ERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSA 3420
            ERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSA
Sbjct: 3361 ERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSA 3420

Query: 3421 FYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS 3480
            FYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS
Sbjct: 3421 FYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS 3480

Query: 3481 GYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEE 3540
            GYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEE
Sbjct: 3481 GYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEE 3540

Query: 3541 DQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISF 3600
            DQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISF
Sbjct: 3541 DQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISF 3600

Query: 3601 ALYVDNRFFTLTVTSLHLVFQMGVIFPQ 3628
            ALYVDNRFFTLTVTSLHLVFQMGVIFPQ
Sbjct: 3601 ALYVDNRFFTLTVTSLHLVFQMGVIFPQ 3628


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
            sapiens]
          Length = 4621

 Score = 6560 bits (17019), Expect = 0.0
 Identities = 3282/3662 (89%), Positives = 3377/3662 (92%), Gaps = 97/3662 (2%)

Query: 1    MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
            MVVSAGPWSSEKAEMNILEINE LRPQLAE KQQF NLKE+CF+TQLAGFLAN+QKKY Y
Sbjct: 1    MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFVTQLAGFLANQQKKYNY 60

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
            EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121  RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
            RSL EHLQALLT DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE
Sbjct: 121  RSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181  KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
            KV +SSAPREVQK EESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL
Sbjct: 181  KVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241  VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
            VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKL PQLA
Sbjct: 241  VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLA 300

Query: 301  EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
            EKKQQFRNLKE+CF+TQL+GFLANQQKKYKYEECKDLIK MLRNERQFKEEKLAEQLKQA
Sbjct: 301  EKKQQFRNLKERCFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQA 360

Query: 361  EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420
            EELRQYKVLVHAQERELTQL+EKLREGRDASRSLNEHLQALLTP EPDKSQGQDLQEQLA
Sbjct: 361  EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420

Query: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            EGCRLAQHLVQKLSPENDNDDDEDVQVE+AEKVQKSSAPREMQKAEEKEVPEDS EECAI
Sbjct: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAI 480

Query: 481  TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 540
            TYSNSHG YDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK
Sbjct: 481  TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 540

Query: 541  GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG 600
            GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG
Sbjct: 541  GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG 600

Query: 601  RHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAF 660
            RHRWDQVKKEDQEATGPRLSRELLDEKGPEV QDS DRCYSTPSGCLELTDSCQPYRSAF
Sbjct: 601  RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF 660

Query: 661  YILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 720
            Y+LEQQR+GLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG
Sbjct: 661  YVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 720

Query: 721  YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780
            YLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPE
Sbjct: 721  YLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPE 780

Query: 781  VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840
            VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
Sbjct: 781  VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840

Query: 841  SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY 900
            SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQPY
Sbjct: 841  SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPY 900

Query: 901  RSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS 960
            RSAFYVLEQQRVG AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS
Sbjct: 901  RSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS 960

Query: 961  TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEV 1020
            TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEV
Sbjct: 961  TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEV 1020

Query: 1021 VEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKR 1080
            VEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKR
Sbjct: 1021 VEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKR 1080

Query: 1081 RGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDS 1140
            RGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDS
Sbjct: 1081 RGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDS 1140

Query: 1141 CQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLD 1200
            CQPYRSAFYVLEQQRVG AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLD
Sbjct: 1141 CQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLD 1200

Query: 1201 RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRE 1260
            RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKD+EEEEDQ PPCPRLSRE
Sbjct: 1201 RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRE 1260

Query: 1261 LLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK 1320
            LLEVV PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK
Sbjct: 1261 LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK 1320

Query: 1321 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 1380
            GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLE
Sbjct: 1321 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLE 1380

Query: 1381 LTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 1440
            LTDSCQPYRSAFYVLEQQRVG+AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ
Sbjct: 1381 LTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 1440

Query: 1441 DSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPC 1500
            DSL+RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEE  EDQ PPC
Sbjct: 1441 DSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEE--EDQGPPC 1498

Query: 1501 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGE 1560
            PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGE
Sbjct: 1499 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE 1558

Query: 1561 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST 1620
            IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST
Sbjct: 1559 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST 1618

Query: 1621 PSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK 1680
            PSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK
Sbjct: 1619 PSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK 1678

Query: 1681 EPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQ 1740
            EPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQ
Sbjct: 1679 EPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQ 1738

Query: 1741 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSL 1800
            GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSL
Sbjct: 1739 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 1798

Query: 1801 DVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR 1860
            DVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR
Sbjct: 1799 DVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR 1858

Query: 1861 CYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSREL 1920
             YSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLSREL
Sbjct: 1859 SYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSREL 1918

Query: 1921 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEE 1980
            LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEE
Sbjct: 1919 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEE 1978

Query: 1981 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHV 2040
            EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HV
Sbjct: 1979 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHV 2038

Query: 2041 GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD 2100
            GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD
Sbjct: 2039 GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD 2098

Query: 2101 SLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRL 2160
            SLDR YSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRL
Sbjct: 2099 SLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRL 2158

Query: 2161 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 2220
            SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KK
Sbjct: 2159 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKK 2218

Query: 2221 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2280
            DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE
Sbjct: 2219 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2278

Query: 2281 ENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 2340
            E HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE
Sbjct: 2279 EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 2338

Query: 2341 VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPS 2400
            VLQDSLDR YSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMDEIEKYQEVEEDQDPS
Sbjct: 2339 VLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPS 2398

Query: 2401 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2460
            CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD
Sbjct: 2399 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2458

Query: 2461 RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 2520
            R KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF
Sbjct: 2459 RTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 2518

Query: 2521 YALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 2580
            YALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE
Sbjct: 2519 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 2578

Query: 2581 KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEED 2640
            KGPEVLQDSLDR YSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMDEIEKYQEVEED
Sbjct: 2579 KGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED 2638

Query: 2641 QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 2700
            QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA
Sbjct: 2639 QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 2698

Query: 2701 LDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2760
            LDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY
Sbjct: 2699 LDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2758

Query: 2761 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE 2820
            GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE
Sbjct: 2759 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE 2818

Query: 2821 LLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQE 2880
            LLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+D+D  +K QE
Sbjct: 2819 LLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQE 2878

Query: 2881 VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 2940
             EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE++
Sbjct: 2879 EEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKH 2938

Query: 2941 LGLALDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQ 2981
            +G +LDV  I+K                    +E EEDQ PPCPRLSRELL+  EPEVLQ
Sbjct: 2939 VGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQ 2998

Query: 2982 DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK 3041
            DSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV               R+KK
Sbjct: 2999 DSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKK 3044

Query: 3042 ERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSA 3101
            +     +E EEDQ PPCPRLSRELL+   P+VLQDSLDRCYSTPS CLE  DSCQPY S+
Sbjct: 3045 D-----QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 3099

Query: 3102 FYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQDPSCPRLSRELLD 3142
            FY LE++ VG ++D+ EIEK                    +E EEDQ+P CPRLSRELLD
Sbjct: 3100 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLD 3159

Query: 3143 EKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEE 3202
            EK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EE
Sbjct: 3160 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEE 3219

Query: 3203 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 3262
            DQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G 
Sbjct: 3220 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 3279

Query: 3263 ALDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 3303
            +LDV  I+K                    +E EEDQ PPCPRLSRELL+   PEVLQDSL
Sbjct: 3280 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 3339

Query: 3304 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 3363
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                 
Sbjct: 3340 DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEK----------------- 3382

Query: 3364 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYV 3423
               +E EEDQ+P CPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y 
Sbjct: 3383 --YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 3440

Query: 3424 LEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 3483
            LE+Q++GLA+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  L
Sbjct: 3441 LEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 3500

Query: 3484 ELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3543
            E PD  QPY S+ Y+LEE+++G +LDV +IEKKGKGKKRRGRRSKKERRRGRKEGEEDQN
Sbjct: 3501 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 3560

Query: 3544 PPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALY 3603
            PPCPRL+  L++ +  EVLQDSLDRCYSTPS   EL DS Q YRS FY  E+Q +  A+ 
Sbjct: 3561 PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 3620

Query: 3604 VD 3605
            +D
Sbjct: 3621 MD 3622



 Score = 5568 bits (14444), Expect = 0.0
 Identities = 2863/3551 (80%), Positives = 3000/3551 (84%), Gaps = 181/3551 (5%)

Query: 169  DEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225
            D DE  + +E E+  + S PR   E+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220

Query: 226  NIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 285
            +   + EE  +   L VDR     E ++        GP               LS E  E
Sbjct: 1221 SAVYSLEEQYLGLALDVDRTKKDQEEEED------QGPPCPR-----------LSRELLE 1263

Query: 286  MNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYE----ECKDLIKFM 341
            +   E+ +    +            + C     S F A ++K   +     E +   K  
Sbjct: 1264 VVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322

Query: 342  LRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLK--EKLREGRDASRSLNEHLQ 399
             R  R+ K+E+   + K+ EE            REL   K  E L++  D S S      
Sbjct: 1323 KRRGRRSKKERRRGR-KEGEE--DQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCL 1379

Query: 400  ALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP 459
             L    +P +S    L++Q   G  +              D DE  + +  E+ Q  S P
Sbjct: 1380 ELTDSCQPYRSAFYVLEQQRV-GLAV--------------DMDEIEKYQEVEEDQDPSCP 1424

Query: 460  R---EMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSS 516
            R   E+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L     
Sbjct: 1425 RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD---- 1480

Query: 517  HVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPE 573
                      +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E
Sbjct: 1481 ----------VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLE 1530

Query: 574  MLASYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEA 614
               S Q Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ  
Sbjct: 1531 QPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNP 1590

Query: 615  TGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDM 674
              PRLSRELLDEKGPEV QDS DRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLA+DM
Sbjct: 1591 PCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM 1650

Query: 675  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 734
            DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA
Sbjct: 1651 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1710

Query: 735  VYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 794
            VYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS
Sbjct: 1711 VYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 1770

Query: 795  SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 854
            SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE
Sbjct: 1771 SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 1830

Query: 855  DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGF 914
            DQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQPYRSAFYVLEQQRVG 
Sbjct: 1831 DQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 1890

Query: 915  AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 974
            AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP
Sbjct: 1891 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 1950

Query: 975  YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 1034
            YSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY
Sbjct: 1951 YSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 2010

Query: 1035 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 1094
            STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK
Sbjct: 2011 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 2070

Query: 1095 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ 1154
            EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQPYRSAFYVLEQQ
Sbjct: 2071 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQ 2130

Query: 1155 RVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 1214
            RVG AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD
Sbjct: 2131 RVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2190

Query: 1215 LGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSL 1274
            LGQPYSSAVYSLEEQYLGLALDVDR KKD+EEEEDQ PPCPRLSRELLEVV PEVLQDSL
Sbjct: 2191 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2250

Query: 1275 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 1334
            DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR
Sbjct: 2251 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2310

Query: 1335 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 1394
            RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQPYRSAFYV
Sbjct: 2311 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYV 2370

Query: 1395 LEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYL 1454
            LEQQRVG+AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL+RCYSTPSGYL
Sbjct: 2371 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 2430

Query: 1455 ELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPE 1514
            ELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEED  Q PPCPRLSRELLEVVEPE
Sbjct: 2431 ELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEED--QGPPCPRLSRELLEVVEPE 2488

Query: 1515 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRR 1574
            VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRR
Sbjct: 2489 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 2548

Query: 1575 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY 1634
            SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQPY
Sbjct: 2549 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPY 2608

Query: 1635 RSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS 1694
            RSAFYVLEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS
Sbjct: 2609 RSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS 2668

Query: 1695 TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEV 1754
            TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEV
Sbjct: 2669 TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEV 2728

Query: 1755 VEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKR 1814
            VEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKR
Sbjct: 2729 VEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKR 2788

Query: 1815 RGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDS 1874
            RGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D 
Sbjct: 2789 RGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2848

Query: 1875 CQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLD 1934
             QPY SA Y LE+Q++GLA+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSLD
Sbjct: 2849 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2908

Query: 1935 RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD----------------- 1977
            RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K                  
Sbjct: 2909 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRR 2968

Query: 1978 --QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYAL 2035
              +E EEDQ PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+L
Sbjct: 2969 GRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSL 3028

Query: 2036 EENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 2095
            EE ++G +LDV               R+KK++     E EEDQ PPCPRLSRELL+   P
Sbjct: 3029 EEQYLGLALDVD--------------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEP 3069

Query: 2096 EVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY--------- 2146
            EVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++HVG ++D+ EIEK          
Sbjct: 3070 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3129

Query: 2147 ----------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 2196
                      +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP
Sbjct: 3130 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 3189

Query: 2197 YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 2256
            YSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY
Sbjct: 3190 YSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 3249

Query: 2257 STPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 2316
            STPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK
Sbjct: 3250 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 3309

Query: 2317 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ 2376
            EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ
Sbjct: 3310 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ 3369

Query: 2377 HVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2436
             VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD
Sbjct: 3370 RVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 3429

Query: 2437 LGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2496
            LGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL
Sbjct: 3430 LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 3489

Query: 2497 DRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 2556
            DRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERR
Sbjct: 3490 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 3549

Query: 2557 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 2616
            RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV
Sbjct: 3550 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 3609

Query: 2617 LEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 2676
            LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL
Sbjct: 3610 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 3669

Query: 2677 ELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 2736
            ELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVL
Sbjct: 3670 ELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 3729

Query: 2737 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 2796
            QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK
Sbjct: 3730 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 3789

Query: 2797 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 2856
            KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS
Sbjct: 3790 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 3849

Query: 2857 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 2916
            AFYVLEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP
Sbjct: 3850 AFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 3909

Query: 2917 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2976
            SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVE
Sbjct: 3910 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVE 3969

Query: 2977 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3036
            PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG
Sbjct: 3970 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 4029

Query: 3037 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQ 3096
            RRSKKERRRGRKEGEEDQ PPCPRLSRELLDEKGP+VLQDSLDRCYSTPSGCLEL DSCQ
Sbjct: 4030 RRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 4089

Query: 3097 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRC 3156
            PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK PEVLQDSLDRC
Sbjct: 4090 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 4149

Query: 3157 YSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 3216
            YSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLSRELL
Sbjct: 4150 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 4209

Query: 3217 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD---- 3272
            +  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K     
Sbjct: 4210 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 4269

Query: 3273 ---------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP 3317
                           +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  
Sbjct: 4270 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 4329

Query: 3318 DSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC 3377
            DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ+P C
Sbjct: 4330 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKY-------------------QEVEEDQDPSC 4370

Query: 3378 PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDE 3437
            PRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+D+D 
Sbjct: 4371 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 4430

Query: 3438 IEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY 3497
             +K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y
Sbjct: 4431 TKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 4490

Query: 3498 SLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVE 3557
            +LEE+++G +LDV +IEKKGKGKKRRGRRSKK+RRRGRKEGEEDQNPPCPRLNGVLMEVE
Sbjct: 4491 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLNGVLMEVE 4550

Query: 3558 EREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLH 3617
            E EVLQDSLD CYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLH
Sbjct: 4551 EPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLH 4610

Query: 3618 LVFQMGVIFPQ 3628
            LVFQMGVIFPQ
Sbjct: 4611 LVFQMGVIFPQ 4621



 Score = 4245 bits (11010), Expect = 0.0
 Identities = 2352/3822 (61%), Positives = 2667/3822 (69%), Gaps = 540/3822 (14%)

Query: 1    MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
            MVVSAGP SSEKAEMNILEINE L PQLAEKKQQFRNLKE+CF+TQLAGFLAN+QKKYKY
Sbjct: 272  MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKY 331

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
            EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 332  EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391

Query: 121  RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSP-ENDEDEDEDVQVEEA 179
            RSL E                               HL   L+P E D+ + +D+Q + A
Sbjct: 392  RSLNE-------------------------------HLQALLTPDEPDKSQGQDLQEQLA 420

Query: 180  EKV-LESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNS 238
            E   L     +++    ++   ED   E A     S  P +  +         EE EV  
Sbjct: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAPREMQKA--------EEKEVP- 471

Query: 239  TLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQ 298
                  E S +EC                  ++   S GP  S +               
Sbjct: 472  ------EDSQEECA-----------------ITYSNSHGPYDSNQPH------------- 495

Query: 299  LAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLK 358
               +K +    ++K   T +            + E +D +  +  NE   +EE+    + 
Sbjct: 496  ---RKTKITFEEDKVDSTLIGSS--------SHVEWEDAVHIIPENESDDEEEEEKGPVS 544

Query: 359  QAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQ 418
                      L  ++E E+ Q      E  D   S       +L  Y+   S    L+EQ
Sbjct: 545  PRN-------LQESEEEEVPQ------ESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQ 591

Query: 419  -LAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDS 474
             +     + +H   ++  E+                Q+++ PR   E+   +  EV +DS
Sbjct: 592  QVCMAVDIGRHRWDQVKKED----------------QEATGPRLSRELLDEKGPEVLQDS 635

Query: 475  LEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDD 534
            L+ C  T S      DS QP+R      E+ ++   +               + E E   
Sbjct: 636  LDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVD--------------MDEIEKYQ 681

Query: 535  EEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQ 591
            E EE++ P  PR    L + +E EV Q+S D  YST S   E+    Q YSS  +SLEEQ
Sbjct: 682  EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 741

Query: 592  QVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTD 651
             + +A+D+ R + DQ ++EDQ    PRLSRELL+   PEV QDS DRCYSTPS CLE  D
Sbjct: 742  YLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 801

Query: 652  SCQPYRSAFYILEQQRVGLAIDMDEIEKY-------------------QEVEEDQDPSCP 692
            SCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ+P CP
Sbjct: 802  SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 861

Query: 693  RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRI 752
            RLSRELLDEK PEVLQDSLDR YSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I
Sbjct: 862  RLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 921

Query: 753  KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYA 812
            +K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+
Sbjct: 922  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 981

Query: 813  LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 872
            LEE+++G +LDV               R+KK++     E EEDQ PPCPRLSRELL+   
Sbjct: 982  LEEQYLGLALDVD--------------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVE 1022

Query: 873  PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKY-------- 924
            PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VGF++D+ EIEK         
Sbjct: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082

Query: 925  -----------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 973
                       +E EEDQ+P CPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  Q
Sbjct: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142

Query: 974  PYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 1033
            PY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRC
Sbjct: 1143 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202

Query: 1034 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 1093
            YSTPS  LE PD  QPY S+ Y+LEE+++G +LDV               R+KK++    
Sbjct: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ---- 1244

Query: 1094 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 1153
             E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE+
Sbjct: 1245 -EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 1303

Query: 1154 QRVGFAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEV 1194
            + VGF++D+ EIEK                    +E EEDQ+P CPRLSRELLDEK PEV
Sbjct: 1304 KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEV 1363

Query: 1195 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPC 1254
            LQDSLDR YSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K +E EEDQDP C
Sbjct: 1364 LQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSC 1423

Query: 1255 PRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE 1314
            PRLSRELL+   PEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  
Sbjct: 1424 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD- 1482

Query: 1315 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST 1374
                         R+KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYST
Sbjct: 1483 -------------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 1524

Query: 1375 PSGCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKY-------------------QEV 1415
            PS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E 
Sbjct: 1525 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 1584

Query: 1416 EEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 1475
            EEDQ+P CPRLSRELLDEK PEVLQDSL+RCYSTPSG LEL D  QPY SA Y LE+Q +
Sbjct: 1585 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 1644

Query: 1476 GLALDVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 1535
            GLA+D+D I+K QE EED  QDP CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD
Sbjct: 1645 GLAVDMDEIEKYQEVEED--QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 1702

Query: 1536 SCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 1595
              QPY S+ Y+LEE ++G +LDV               R+KK++     E EEDQ PPCP
Sbjct: 1703 LGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----EEEEDQGPPCP 1743

Query: 1596 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEI 1655
            RLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++HVG ++D+ EI
Sbjct: 1744 RLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEI 1803

Query: 1656 EKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 1696
            EK                    +E EEDQ+P CPRLSRELLDEK PEVLQDSLDR YSTP
Sbjct: 1804 EKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTP 1863

Query: 1697 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756
            SG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  E
Sbjct: 1864 SGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE 1923

Query: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816
            PEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV              
Sbjct: 1924 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD------------- 1970

Query: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876
             R+KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQ
Sbjct: 1971 -RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQ 2024

Query: 1877 PYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLS 1917
            PY S+FY LE++HVG ++D+ EIEK                    +E EEDQ+P CPRLS
Sbjct: 2025 PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS 2084

Query: 1918 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 1977
            RELLDEK PEVLQDSLDR YSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K 
Sbjct: 2085 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY 2144

Query: 1978 QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 2037
            QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE
Sbjct: 2145 QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 2204

Query: 2038 NHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEV 2097
             ++G +LDV               R+KK++     E EEDQ PPCPRLSRELL+   PEV
Sbjct: 2205 QYLGLALDVD--------------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEV 2245

Query: 2098 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY----------- 2146
            LQDSLDRCYSTPS CLE  DSCQPY S+FY LE++HVG ++D+ EIEK            
Sbjct: 2246 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 2305

Query: 2147 --------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
                    +E EEDQ+P CPRLSRELLDEK PEVLQDSLDR YSTPSG LEL D  QPY 
Sbjct: 2306 KKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYR 2365

Query: 2199 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 2258
            SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYST
Sbjct: 2366 SAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYST 2425

Query: 2259 PSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 2318
            PS  LE PD  QPY S+ Y+LEE ++G +LDV               R+KK++     E 
Sbjct: 2426 PSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----EE 2466

Query: 2319 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHV 2378
            EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++HV
Sbjct: 2467 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHV 2526

Query: 2379 GLAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQD 2419
            G ++D+ EIEK                    +E EEDQ+P CPRLSRELLDEK PEVLQD
Sbjct: 2527 GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD 2586

Query: 2420 SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRL 2479
            SLDR YSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRL
Sbjct: 2587 SLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRL 2646

Query: 2480 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEK 2539
            SRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV     
Sbjct: 2647 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD---- 2702

Query: 2540 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSG 2599
                      R+KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS 
Sbjct: 2703 ----------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 2747

Query: 2600 CLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEED 2640
            CLE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EED
Sbjct: 2748 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 2807

Query: 2641 QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 2700
            Q+P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA
Sbjct: 2808 QNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 2867

Query: 2701 LDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2760
            LDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY
Sbjct: 2868 LDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2927

Query: 2761 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE 2820
            GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE
Sbjct: 2928 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE 2987

Query: 2821 LLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQE 2880
            LLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+D+D  +K QE
Sbjct: 2988 LLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQE 3047

Query: 2881 VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 2940
             EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE++
Sbjct: 3048 EEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKH 3107

Query: 2941 LGLALDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQ 2981
            +G +LDV  I+K                    +E EEDQ PPCPRLSRELL+  EPEVLQ
Sbjct: 3108 VGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQ 3167

Query: 2982 DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK 3041
            DSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV               R+KK
Sbjct: 3168 DSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKK 3213

Query: 3042 ERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSA 3101
            ++     E EEDQ PPCPRLSRELL+   P+VLQDSLDRCYSTPS CLE  DSCQPY S+
Sbjct: 3214 DQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 3268

Query: 3102 FYVLEQQRVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELLD 3142
            FY LE++ VG ++D+ EIEK                    +E EEDQ+P CPRLSRELLD
Sbjct: 3269 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLD 3328

Query: 3143 EKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEE 3202
            EKGPEVLQDSLDRCYSTPSGCLEL DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEE
Sbjct: 3329 EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEE 3388

Query: 3203 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 3262
            DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL
Sbjct: 3389 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 3448

Query: 3263 ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 3322
            ALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP
Sbjct: 3449 ALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 3508

Query: 3323 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 3382
            YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR
Sbjct: 3509 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 3568

Query: 3383 ELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQ 3442
            ELLDEKGPEVLQDSLDRCYSTPSGCLEL DSCQPYRSAFYVLEQQ VGLAVDMDEIEKYQ
Sbjct: 3569 ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQ 3628

Query: 3443 EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 3502
            EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ
Sbjct: 3629 EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 3688

Query: 3503 YLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVL 3562
            YLGLALDVD              R+KK+     +E EEDQ PPCPRL+  L+EV E EVL
Sbjct: 3689 YLGLALDVD--------------RTKKD-----QEEEEDQGPPCPRLSRELLEVVEPEVL 3729

Query: 3563 QDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYV 3604
            QDSLDRCYSTPS   E PDS Q Y S FY+ EE+H+ F+L V
Sbjct: 3730 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3771



 Score = 4043 bits (10486), Expect = 0.0
 Identities = 2181/3357 (64%), Positives = 2448/3357 (72%), Gaps = 418/3357 (12%)

Query: 460  REMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 519
            RE+   +  EV +DSL+    T S      DS QP+R      E+ +V   +        
Sbjct: 865  RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 917

Query: 520  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 576
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 918  -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 970

Query: 577  SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQ 636
              Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+   PEV QDS 
Sbjct: 971  LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 1030

Query: 637  DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKY---------------- 680
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                 
Sbjct: 1031 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 1090

Query: 681  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 737
               +E EEDQ+P CPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y 
Sbjct: 1091 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 1150

Query: 738  LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 797
            LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  L
Sbjct: 1151 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 1210

Query: 798  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 857
            E PD  QPY S+ Y+LEE+++G +LDV               R+KK++     E EEDQ 
Sbjct: 1211 ELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----EEEEDQG 1251

Query: 858  PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVD 917
            PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VGF++D
Sbjct: 1252 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 1311

Query: 918  MDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
            + EIEK                    +E EEDQ+P CPRLSRELLDEK PEVLQDSLDR 
Sbjct: 1312 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRS 1371

Query: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018
            YSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL
Sbjct: 1372 YSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 1431

Query: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078
            +  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV          
Sbjct: 1432 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------- 1482

Query: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138
                 R+KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  
Sbjct: 1483 -----RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP 1532

Query: 1139 DSCQPYRSAFYVLEQQRVGFAVDMDEIEKY-------------------QEVEEDQDPSC 1179
            DSCQPY S+FY LE++ VGF++D+ EIEK                    +E EEDQ+P C
Sbjct: 1533 DSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC 1592

Query: 1180 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 1239
            PRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D 
Sbjct: 1593 PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDE 1652

Query: 1240 IKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 1299
            I+K +E EEDQDP CPRLSRELL+   PEVLQDSLDRCYSTPS  LE PD  QPY S+ Y
Sbjct: 1653 IEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY 1712

Query: 1300 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 1359
            +LEE+++G +LDV               R+KK++     E EEDQ PPCPRLSRELL+  
Sbjct: 1713 SLEEQYLGLALDVD--------------RTKKDQ-----EEEEDQGPPCPRLSRELLEVV 1753

Query: 1360 GPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKY------- 1412
             PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK        
Sbjct: 1754 EPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRR 1813

Query: 1413 ------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLG 1460
                        +E EEDQ+P CPRLSRELLDEK PEVLQDSL+R YSTPSG LEL D  
Sbjct: 1814 GRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSC 1873

Query: 1461 QPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSL 1520
            QPY SA Y LE+Q +GLA+D+D I+K QE EED  QDP CPRLSRELL+  EPEVLQDSL
Sbjct: 1874 QPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED--QDPSCPRLSRELLDEKEPEVLQDSL 1931

Query: 1521 DRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 1580
            DRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV               R+KK++ 
Sbjct: 1932 DRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ- 1976

Query: 1581 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 1640
                E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY 
Sbjct: 1977 ----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYA 2032

Query: 1641 LEQQHVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKE 1681
            LE++HVG ++D+ EIEK                    +E EEDQ+P CPRLSRELLDEK 
Sbjct: 2033 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 2092

Query: 1682 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 1741
            PEVLQDSLDR YSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ 
Sbjct: 2093 PEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQD 2152

Query: 1742 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLD 1801
            P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LD
Sbjct: 2153 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 2212

Query: 1802 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRC 1861
            V               R+KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRC
Sbjct: 2213 VD--------------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 2253

Query: 1862 YSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY------------------- 1902
            YSTPS CLE  DSCQPY S+FY LE++HVG ++D+ EIEK                    
Sbjct: 2254 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 2313

Query: 1903 QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1962
            +E EEDQ+P CPRLSRELLDEK PEVLQDSLDR YSTPSG LEL D  QPY SA Y LE+
Sbjct: 2314 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQ 2373

Query: 1963 QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP 2022
            Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE P
Sbjct: 2374 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2433

Query: 2023 DSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC 2082
            D  QPY S+ Y+LEE ++G +LDV               R+KK++     E EEDQ PPC
Sbjct: 2434 DLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----EEEEDQGPPC 2474

Query: 2083 PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDE 2142
            PRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++HVG ++D+ E
Sbjct: 2475 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE 2534

Query: 2143 IEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYST 2183
            IEK                    +E EEDQ+P CPRLSRELLDEK PEVLQDSLDR YST
Sbjct: 2535 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYST 2594

Query: 2184 PSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVV 2243
            PSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  
Sbjct: 2595 PSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK 2654

Query: 2244 EPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRR 2303
            EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV             
Sbjct: 2655 EPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD------------ 2702

Query: 2304 GRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSC 2363
              R+KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSC
Sbjct: 2703 --RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2755

Query: 2364 QPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRL 2404
            QPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ+P CPRL
Sbjct: 2756 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2815

Query: 2405 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 2464
            SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KK
Sbjct: 2816 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKK 2875

Query: 2465 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2524
            DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE
Sbjct: 2876 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2935

Query: 2525 ENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 2584
            E HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK PE
Sbjct: 2936 EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPE 2995

Query: 2585 VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPS 2644
            VLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+D+D  +K QE EEDQ P 
Sbjct: 2996 VLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPP 3055

Query: 2645 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2704
            CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV 
Sbjct: 3056 CPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVG 3115

Query: 2705 RIKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 2745
             I+K                    +E EEDQ PPCPRLSRELL+  EPEVLQDSLDRCYS
Sbjct: 3116 EIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYS 3175

Query: 2746 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 2805
            TPS  LE PD  QPY S+ Y+LEE+++G +LDV               R+KK++     E
Sbjct: 3176 TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----E 3216

Query: 2806 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQH 2865
             EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++H
Sbjct: 3217 EEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKH 3276

Query: 2866 VGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQ 2906
            VG ++D+ EIEK                    +E EEDQ+P CPRLSRELLDEK PEVLQ
Sbjct: 3277 VGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQ 3336

Query: 2907 DSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPR 2966
            DSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPR
Sbjct: 3337 DSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPR 3396

Query: 2967 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 3026
            LSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV    
Sbjct: 3397 LSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--- 3453

Query: 3027 KKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPS 3086
                       R+KK++     E EEDQ PPCPRLSRELL+   P+VLQDSLDRCYSTPS
Sbjct: 3454 -----------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 3497

Query: 3087 GCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY-------------------QEVEE 3127
             CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EE
Sbjct: 3498 SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 3557

Query: 3128 DQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGL 3187
            DQ+P CPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL DSCQPYRSAFY+LEQQRVGL
Sbjct: 3558 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 3617

Query: 3188 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 3247
            AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP
Sbjct: 3618 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 3677

Query: 3248 YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 3307
            YSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY
Sbjct: 3678 YSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 3737

Query: 3308 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 3367
            STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK
Sbjct: 3738 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 3797

Query: 3368 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQ 3427
            EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL DSCQPYRSAFYVLEQQ
Sbjct: 3798 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ 3857

Query: 3428 HVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 3487
             VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD
Sbjct: 3858 RVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 3917

Query: 3488 LGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3547
            LGQPYSSAVYSLEEQYLGLALDVD              R+KK+     +E EEDQ PPCP
Sbjct: 3918 LGQPYSSAVYSLEEQYLGLALDVD--------------RTKKD-----QEEEEDQGPPCP 3958

Query: 3548 RLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYV 3604
            RL+  L+EV E EVLQDSLDRCYSTPS   E PDS Q Y S FY+ EE+H+ F+L V
Sbjct: 3959 RLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 4015


>gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sapiens]
          Length = 3815

 Score = 5979 bits (15511), Expect = 0.0
 Identities = 2992/3421 (87%), Positives = 3101/3421 (90%), Gaps = 112/3421 (3%)

Query: 259  PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL 318
            PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFRNLKE+CF+TQL
Sbjct: 8    PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQL 67

Query: 319  SGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378
            +GFLANQQKKYKYEECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT
Sbjct: 68   AGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 127

Query: 379  QLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438
            QL+EKLREGRDASRSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND
Sbjct: 128  QLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 187

Query: 439  NDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKT 498
            NDDDEDVQVE+AEKVQKSSAPREMQKAEEKEVPEDS EECAITYSNSHG YDSNQPHRKT
Sbjct: 188  NDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKT 247

Query: 499  KITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 558
            KITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ
Sbjct: 248  KITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 307

Query: 559  ESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPR 618
            ESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPR
Sbjct: 308  ESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPR 367

Query: 619  LSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIE 678
            LSRELLDEKGPEV QDS DRCYSTPSGCLELTDSCQPYRSAFY+LEQQR+GLA+DMDEIE
Sbjct: 368  LSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVDMDEIE 427

Query: 679  KYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSL 738
            KYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSL
Sbjct: 428  KYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSL 487

Query: 739  EEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLE 798
            EEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLE
Sbjct: 488  EEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLE 547

Query: 799  QPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNP 858
            QPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNP
Sbjct: 548  QPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNP 607

Query: 859  PCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDM 918
            PCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG AVDM
Sbjct: 608  PCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM 667

Query: 919  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 978
            DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA
Sbjct: 668  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 727

Query: 979  VYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 1038
            VYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS
Sbjct: 728  VYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 787

Query: 1039 SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 1098
            SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE
Sbjct: 788  SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 847

Query: 1099 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGF 1158
            DQNPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +G 
Sbjct: 848  DQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 907

Query: 1159 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 1218
            A+D+DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP
Sbjct: 908  ALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 967

Query: 1219 YSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCY 1278
            YSSAVYSLEEQYLGLALDVDR KKD+EEEEDQ PPCPRLSRELLEVV PEVLQDSLDRCY
Sbjct: 968  YSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 1027

Query: 1279 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 1338
            STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK
Sbjct: 1028 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 1087

Query: 1339 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ 1398
            EGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q
Sbjct: 1088 EGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 1147

Query: 1399 RVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPD 1458
             +G+A+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSL+RCYSTPS  LE PD
Sbjct: 1148 YLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 1207

Query: 1459 LGQPYSSAVYSLEEQYLGLALDVDRIKKDQE-----------------EEEDEDQDPPCP 1501
              QPY S+ Y+LEE+++G +LDV  I+K  +                 +E +EDQ+PPCP
Sbjct: 1208 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 1267

Query: 1502 RLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEI 1561
            RLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV   
Sbjct: 1268 RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD-- 1325

Query: 1562 EKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTP 1621
                        R+KK+     +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTP
Sbjct: 1326 ------------RTKKD-----QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 1368

Query: 1622 SGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVE 1662
            S CLE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E E
Sbjct: 1369 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 1428

Query: 1663 EDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLG 1722
            EDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLG
Sbjct: 1429 EDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLG 1488

Query: 1723 LALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQ 1782
            LALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQ
Sbjct: 1489 LALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQ 1548

Query: 1783 PYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS 1842
            PYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS
Sbjct: 1549 PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS 1608

Query: 1843 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY 1902
            RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMDEIEKY
Sbjct: 1609 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY 1668

Query: 1903 QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1962
            QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE
Sbjct: 1669 QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1728

Query: 1963 QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP 2022
            QYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP
Sbjct: 1729 QYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP 1788

Query: 2023 DSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC 2082
            DSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC
Sbjct: 1789 DSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC 1848

Query: 2083 PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDE 2142
            PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMDE
Sbjct: 1849 PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDE 1908

Query: 2143 IEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY 2202
            IEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY
Sbjct: 1909 IEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY 1968

Query: 2203 SLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 2262
            SLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC
Sbjct: 1969 SLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 2028

Query: 2263 LEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 2322
            LEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ
Sbjct: 2029 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 2088

Query: 2323 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV 2382
            NPPCPRLSRELLDEKGPEVLQDSLDR YSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAV
Sbjct: 2089 NPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV 2148

Query: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442
            DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS
Sbjct: 2149 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2208

Query: 2443 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 2502
            SAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST
Sbjct: 2209 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYST 2268

Query: 2503 PSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 2562
            PSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG
Sbjct: 2269 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 2328

Query: 2563 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHV 2622
            EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ V
Sbjct: 2329 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 2388

Query: 2623 GLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLG 2682
            GLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLG
Sbjct: 2389 GLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLG 2448

Query: 2683 QPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDR 2742
            QPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDR
Sbjct: 2449 QPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDR 2508

Query: 2743 CYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRG 2802
            CYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRG
Sbjct: 2509 CYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRG 2568

Query: 2803 RKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 2862
            RKEGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE
Sbjct: 2569 RKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLE 2628

Query: 2863 QQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 2922
            +Q++GLA+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE 
Sbjct: 2629 EQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 2688

Query: 2923 PDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQGPP 2963
            PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ PP
Sbjct: 2689 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 2748

Query: 2964 CPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVG 3023
            CPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ 
Sbjct: 2749 CPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 2808

Query: 3024 EIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYS 3083
            EIEK                    +E EEDQ+P CPRLSRELLDEK P+VLQDSLDRCYS
Sbjct: 2809 EIEK-------------------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYS 2849

Query: 3084 TPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDE 3143
            TPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P CPRLSRELL+ 
Sbjct: 2850 TPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEV 2909

Query: 3144 KGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEK------- 3196
              PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK       
Sbjct: 2910 VEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKR 2969

Query: 3197 ------------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3244
                         +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL
Sbjct: 2970 RGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3029

Query: 3245 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 3304
            GQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD
Sbjct: 3030 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 3089

Query: 3305 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRR 3364
            RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRR
Sbjct: 3090 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRR 3149

Query: 3365 GRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVL 3424
            GRKEGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y L
Sbjct: 3150 GRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSL 3209

Query: 3425 EQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLE 3484
            E+Q++GLA+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE
Sbjct: 3210 EEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLE 3269

Query: 3485 LPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNP 3544
             PD  QPY S+ Y+LEE+++G +LDV +IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNP
Sbjct: 3270 QPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNP 3329

Query: 3545 PCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYV 3604
            PCPRL+  L++ +E EVLQDSLDRCYSTPS Y ELPD  Q Y S  YS EEQ++  AL V
Sbjct: 3330 PCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDV 3389

Query: 3605 D 3605
            D
Sbjct: 3390 D 3390



 Score = 4558 bits (11823), Expect = 0.0
 Identities = 2471/3802 (64%), Positives = 2763/3802 (72%), Gaps = 460/3802 (12%)

Query: 1    MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
            MVVSAGP SSEKAEMNILEINE L PQLAEKKQQFRNLKE+CF+TQLAGFLAN+QKKYKY
Sbjct: 21   MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKY 80

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
            EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 81   EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 140

Query: 121  RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSP-ENDEDEDEDVQVEEA 179
            RSL E                               HL   L+P E D+ + +D+Q + A
Sbjct: 141  RSLNE-------------------------------HLQALLTPDEPDKSQGQDLQEQLA 169

Query: 180  EKV-LESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNS 238
            E   L     +++    ++   ED   E A     S  P +  +         EE EV  
Sbjct: 170  EGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAPREMQKA--------EEKEVP- 220

Query: 239  TLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQ 298
                  E S +EC                  ++   S GP  S +               
Sbjct: 221  ------EDSQEECA-----------------ITYSNSHGPYDSNQPH------------- 244

Query: 299  LAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLK 358
               +K +    ++K   T +            + E +D +  +  NE   +EE+    + 
Sbjct: 245  ---RKTKITFEEDKVDSTLIGSS--------SHVEWEDAVHIIPENESDDEEEEEKGPVS 293

Query: 359  QAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQ 418
                      L  ++E E+ Q      E  D   S       +L  Y+   S    L+EQ
Sbjct: 294  PRN-------LQESEEEEVPQ------ESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQ 340

Query: 419  -LAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDS 474
             +     + +H   ++  E+                Q+++ PR   E+   +  EV +DS
Sbjct: 341  QVCMAVDIGRHRWDQVKKED----------------QEATGPRLSRELLDEKGPEVLQDS 384

Query: 475  LEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDD 534
            L+ C  T S      DS QP+R      E+ ++   +               + E E   
Sbjct: 385  LDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGLAVD--------------MDEIEKYQ 430

Query: 535  EEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQ 591
            E EE++ P  PR    L + +E EV Q+S D  YST S   E+    Q YSS  +SLEEQ
Sbjct: 431  EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 490

Query: 592  QVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTD 651
             + +A+D+ R + DQ ++EDQ    PRLSRELL+   PEV QDS DRCYSTPS CLE  D
Sbjct: 491  YLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 550

Query: 652  SCQPYRSAFYILEQQRVGLAIDMDEIEKY-------------------QEVEEDQDPSCP 692
            SCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ+P CP
Sbjct: 551  SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 610

Query: 693  RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRI 752
            RLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I
Sbjct: 611  RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEI 670

Query: 753  KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYA 812
            +K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+
Sbjct: 671  EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 730

Query: 813  LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 872
            LEE+++G +LDV               R+KK++     E EEDQ PPCPRLSRELL+   
Sbjct: 731  LEEQYLGLALDVD--------------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVE 771

Query: 873  PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKY-------- 924
            PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VGF++D+ EIEK         
Sbjct: 772  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 831

Query: 925  -----------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 973
                       +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ
Sbjct: 832  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 891

Query: 974  PYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 1033
            PYSSAVYSLEEQYLGLALDVD I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRC
Sbjct: 892  PYSSAVYSLEEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 951

Query: 1034 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 1093
            YSTPS  LE PD  QPY S+ Y+LEE+++G +LDV               R+KK++    
Sbjct: 952  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ---- 993

Query: 1094 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 1153
             E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE+
Sbjct: 994  -EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 1052

Query: 1154 QRVGFAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEV 1194
            + VGF++D+ EIEK                    +E EEDQ+P CPRLSRELLDEKEPEV
Sbjct: 1053 KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEV 1112

Query: 1195 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPC 1254
            LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKD+EEEEDQ PPC
Sbjct: 1113 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPC 1172

Query: 1255 PRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE 1314
            PRLSRELLEVV PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE
Sbjct: 1173 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE 1232

Query: 1315 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST 1374
            IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYST
Sbjct: 1233 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYST 1292

Query: 1375 PSGCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK 1434
            PSG LEL D  QPY SA Y LE+Q +G+A+D+D  +K QE EEDQ P CPRLSRELL+  
Sbjct: 1293 PSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVV 1352

Query: 1435 EPEVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQE----- 1489
            EPEVLQDSL+RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K  +     
Sbjct: 1353 EPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRR 1412

Query: 1490 ------------EEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 1537
                        +E +EDQ+PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  
Sbjct: 1413 GRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLG 1472

Query: 1538 QPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 1597
            QPY S+ Y+LEE ++G +LDV               R+KK++     E EEDQ PPCPRL
Sbjct: 1473 QPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----EEEEDQGPPCPRL 1513

Query: 1598 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK 1657
            SRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++HVG ++D+ EIEK
Sbjct: 1514 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK 1573

Query: 1658 Y-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 1698
                                +E EEDQ+P CPRLSRELLDEK PEVLQDSLDRCYSTPSG
Sbjct: 1574 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSG 1633

Query: 1699 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 1758
             LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPE
Sbjct: 1634 CLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPE 1693

Query: 1759 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRR 1818
            VLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV               R
Sbjct: 1694 VLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------R 1739

Query: 1819 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY 1878
            +KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY
Sbjct: 1740 TKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1794

Query: 1879 RSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRE 1919
             S+FY LE++HVG ++D+ EIEK                    +E EEDQ+P CPRLSRE
Sbjct: 1795 GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE 1854

Query: 1920 LLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQE 1979
            LLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE
Sbjct: 1855 LLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQE 1914

Query: 1980 EEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENH 2039
             EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE +
Sbjct: 1915 VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 1974

Query: 2040 VGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQ 2099
            +G +LDV               R+KK++     E EEDQ PPCPRLSRELL+   PEVLQ
Sbjct: 1975 LGLALDVD--------------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQ 2015

Query: 2100 DSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY------------- 2146
            DSLDRCYSTPS CLE  DSCQPY S+FY LE++HVG ++D+ EIEK              
Sbjct: 2016 DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK 2075

Query: 2147 ------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2200
                  +E EEDQ+P CPRLSRELLDEK PEVLQDSLDR YSTPSG LEL D  QPY SA
Sbjct: 2076 ERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSA 2135

Query: 2201 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2260
             Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS
Sbjct: 2136 FYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPS 2195

Query: 2261 SCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 2320
              LE PD  QPY S+ Y+LEE ++G +LDV               R+KK++     E EE
Sbjct: 2196 GYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----EEEE 2236

Query: 2321 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGL 2380
            DQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++HVG 
Sbjct: 2237 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 2296

Query: 2381 AVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 2421
            ++D+ EIEK                    +E EEDQ+P CPRLSRELLDEK PEVLQDSL
Sbjct: 2297 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 2356

Query: 2422 DRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSR 2481
            DRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSR
Sbjct: 2357 DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSR 2416

Query: 2482 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKG 2541
            ELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV       
Sbjct: 2417 ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD------ 2470

Query: 2542 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCL 2601
                    R+KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CL
Sbjct: 2471 --------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 2517

Query: 2602 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQD 2642
            E  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ+
Sbjct: 2518 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 2577

Query: 2643 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 2702
            P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD
Sbjct: 2578 PPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 2637

Query: 2703 VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGS 2762
            VDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGS
Sbjct: 2638 VDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGS 2697

Query: 2763 SFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELL 2822
            SFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELL
Sbjct: 2698 SFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELL 2757

Query: 2823 DEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVE 2882
            DEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMDEIEKYQEVE
Sbjct: 2758 DEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVE 2817

Query: 2883 EDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLG 2942
            EDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLG
Sbjct: 2818 EDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLG 2877

Query: 2943 LALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQ 3002
            LALDVDR KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQ
Sbjct: 2878 LALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQ 2937

Query: 3003 PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS 3062
            PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS
Sbjct: 2938 PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLS 2997

Query: 3063 RELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY 3122
            RELLDEK P+VLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K 
Sbjct: 2998 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKD 3057

Query: 3123 QEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQ 3182
            QE EEDQ P CPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE+
Sbjct: 3058 QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 3117

Query: 3183 QRVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEV 3223
            + VG ++D+ EIEK                    +E EEDQ+P CPRLSRELLDEKEPEV
Sbjct: 3118 KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEV 3177

Query: 3224 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPC 3283
            LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPC
Sbjct: 3178 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPC 3237

Query: 3284 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE 3343
            PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE
Sbjct: 3238 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE 3297

Query: 3344 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST 3403
            IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYST
Sbjct: 3298 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYST 3357

Query: 3404 PSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK 3463
            PSG LEL D  QPY SA Y LE+Q++GLA+D+D  +K QE EEDQ P CPRLSRELL+  
Sbjct: 3358 PSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVV 3417

Query: 3464 EPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRR 3523
            EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV +IEKKGKGKKRR
Sbjct: 3418 EPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRR 3477

Query: 3524 GRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSF 3583
            GRRSKKERRRGRKEGEEDQNPPCPRL+  L++ +  EVLQDSLDR YSTPS   EL DS 
Sbjct: 3478 GRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSC 3537

Query: 3584 QHYRSVFYSFEEQHISFALYVD 3605
            Q YRS FY  E+Q +  A+ +D
Sbjct: 3538 QPYRSAFYVLEQQRVGLAVDMD 3559



 Score = 4199 bits (10889), Expect = 0.0
 Identities = 2237/3370 (66%), Positives = 2500/3370 (74%), Gaps = 380/3370 (11%)

Query: 460  REMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 519
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 614  RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD------- 666

Query: 520  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 576
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 667  -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 719

Query: 577  SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQ 636
              Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+   PEV QDS 
Sbjct: 720  LGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 779

Query: 637  DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKY---------------- 680
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                 
Sbjct: 780  DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 839

Query: 681  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 737
               +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS
Sbjct: 840  RGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 899

Query: 738  LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 797
            LEEQYLGLALDVD I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  L
Sbjct: 900  LEEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 959

Query: 798  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 857
            E PD  QPY S+ Y+LEE+++G +LDV               R+KK++     E EEDQ 
Sbjct: 960  ELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----EEEEDQG 1000

Query: 858  PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVD 917
            PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VGF++D
Sbjct: 1001 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 1060

Query: 918  MDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
            + EIEK                    +E EEDQ+P CPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 1061 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRC 1120

Query: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KKDQEEEEDQGPPCPRLSRELL
Sbjct: 1121 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELL 1180

Query: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1181 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1240

Query: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL 
Sbjct: 1241 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1300

Query: 1139 DSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1198
            D  QPY SA Y LE+Q +G A+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDS
Sbjct: 1301 DLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS 1360

Query: 1199 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD--------------- 1243
            LDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K                
Sbjct: 1361 LDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKER 1420

Query: 1244 ----EEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 1299
                +E EEDQ+PPCPRLSRELL+   PEVLQDSLDRCYSTPS  LE PD  QPY S+ Y
Sbjct: 1421 RRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY 1480

Query: 1300 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 1359
            +LEE+++G +LDV               R+KK++     E EEDQ PPCPRLSRELL+  
Sbjct: 1481 SLEEQYLGLALDVD--------------RTKKDQ-----EEEEDQGPPCPRLSRELLEVV 1521

Query: 1360 GPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKY------- 1412
             PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK        
Sbjct: 1522 EPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRR 1581

Query: 1413 ------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLG 1460
                        +E EEDQ+P CPRLSRELLDEK PEVLQDSL+RCYSTPSG LEL D  
Sbjct: 1582 GRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSC 1641

Query: 1461 QPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSL 1520
            QPY SA Y LE+Q +GLA+D+D I+K QE EED  QDP CPRLSRELL+  EPEVLQDSL
Sbjct: 1642 QPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED--QDPSCPRLSRELLDEKEPEVLQDSL 1699

Query: 1521 DRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 1580
            DRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV               R+KK++ 
Sbjct: 1700 DRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ- 1744

Query: 1581 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 1640
                E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY 
Sbjct: 1745 ----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYA 1800

Query: 1641 LEQQHVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKE 1681
            LE++HVG ++D+ EIEK                    +E EEDQ+P CPRLSRELLDEK 
Sbjct: 1801 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 1860

Query: 1682 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 1741
            PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ 
Sbjct: 1861 PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQD 1920

Query: 1742 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLD 1801
            P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LD
Sbjct: 1921 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 1980

Query: 1802 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRC 1861
            V               R+KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRC
Sbjct: 1981 VD--------------RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRC 2021

Query: 1862 YSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY------------------- 1902
            YSTPS CLE  DSCQPY S+FY LE++HVG ++D+ EIEK                    
Sbjct: 2022 YSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR 2081

Query: 1903 QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1962
            +E EEDQ+P CPRLSRELLDEK PEVLQDSLDR YSTPSG LEL D  QPY SA Y LE+
Sbjct: 2082 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQ 2141

Query: 1963 QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQP 2022
            Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE P
Sbjct: 2142 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 2201

Query: 2023 DSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPC 2082
            D  QPY S+ Y+LEE ++G +LDV               R+KK++     E EEDQ PPC
Sbjct: 2202 DLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-----EEEEDQGPPC 2242

Query: 2083 PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDE 2142
            PRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++HVG ++D+ E
Sbjct: 2243 PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGE 2302

Query: 2143 IEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYST 2183
            IEK                    +E EEDQ+P CPRLSRELLDEK PEVLQDSLDRCYST
Sbjct: 2303 IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYST 2362

Query: 2184 PSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVV 2243
            PSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  
Sbjct: 2363 PSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK 2422

Query: 2244 EPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRR 2303
            EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV             
Sbjct: 2423 EPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD------------ 2470

Query: 2304 GRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSC 2363
              R+KK++     E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS CLE  DSC
Sbjct: 2471 --RTKKDQ-----EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 2523

Query: 2364 QPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRL 2404
            QPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ+P CPRL
Sbjct: 2524 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 2583

Query: 2405 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 2464
            SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR KK
Sbjct: 2584 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKK 2643

Query: 2465 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2524
            DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE
Sbjct: 2644 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2703

Query: 2525 ENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 2584
            E HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE
Sbjct: 2704 EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 2763

Query: 2585 VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPS 2644
            VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMDEIEKYQEVEEDQDPS
Sbjct: 2764 VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPS 2823

Query: 2645 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2704
            CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD
Sbjct: 2824 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2883

Query: 2705 RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 2764
            R KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF
Sbjct: 2884 RTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 2943

Query: 2765 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 2824
            YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE
Sbjct: 2944 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 3003

Query: 2825 KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEED 2884
            K PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+D+D  +K QE EED
Sbjct: 3004 KEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEED 3063

Query: 2885 QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 2944
            Q P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +
Sbjct: 3064 QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFS 3123

Query: 2945 LDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2985
            LDV  I+K                    +E EEDQ PPCPRLSRELL+  EPEVLQDSLD
Sbjct: 3124 LDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEPEVLQDSLD 3183

Query: 2986 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRR 3045
            RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV               R+KK++  
Sbjct: 3184 RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD--------------RTKKDQ-- 3227

Query: 3046 GRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVL 3105
               E EEDQ PPCPRLSRELL+   P+VLQDSLDRCYSTPS CLE  DSCQPY S+FY L
Sbjct: 3228 ---EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYAL 3284

Query: 3106 EQQRVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKGP 3146
            E++ VG ++D+ EIEK                    +E EEDQ+P CPRLSRELLDEK P
Sbjct: 3285 EEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKEP 3344

Query: 3147 EVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDP 3206
            EVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D  +K QE EEDQ P
Sbjct: 3345 EVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGP 3404

Query: 3207 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDV 3266
             CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV
Sbjct: 3405 PCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3464

Query: 3267 DRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 3307
              I+K                    +E EEDQ PPCPRLSRELL+   PEVLQDSLDR Y
Sbjct: 3465 GEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSY 3524

Query: 3308 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 3367
            STPS CLE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +
Sbjct: 3525 STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY-------------------Q 3565

Query: 3368 EGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQ 3427
            E EEDQ+P CPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q
Sbjct: 3566 EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 3625

Query: 3428 HVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 3487
            ++GLA+D+D  +K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD
Sbjct: 3626 YLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 3685

Query: 3488 LGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3547
              QPY S+ Y+LEE+++G +LDV +IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP
Sbjct: 3686 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3745

Query: 3548 RLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNR 3607
            RL+  L++ +  EVLQDSLDRCYSTPS   EL DS Q YRS FY  E+Q +  A+ +D  
Sbjct: 3746 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDGE 3805

Query: 3608 FFTLTVTSLH 3617
            + ++ V  +H
Sbjct: 3806 YLSMKVIRIH 3815



 Score =  188 bits (478), Expect = 7e-47
 Identities = 173/518 (33%), Positives = 231/518 (44%), Gaps = 81/518 (15%)

Query: 189  REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSH 248
            RE+   +E +V +DSL+ C  T S      D  QP+ +   + EE  +   L VDR    
Sbjct: 3336 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKD 3395

Query: 249  DECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRN 308
             E ++        GP               LS E  E+   E+ +    +          
Sbjct: 3396 QEEEED------QGPPCPR-----------LSRELLEVVEPEVLQDSLDRCYSTPSSCLE 3438

Query: 309  LKEKCFLTQLSGFLANQQKKYKYE----ECKDLIKFMLRNERQFKEEKLAEQLKQAEELR 364
              + C     S F A ++K   +     E +   K   R  R+ K+E+   + K+ EE  
Sbjct: 3439 QPDSC-QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR-KEGEE-- 3494

Query: 365  QYKVLVHAQERELTQLK--EKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEG 422
                      REL   K  E L++  D S S       L    +P +S    L++Q   G
Sbjct: 3495 DQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRV-G 3553

Query: 423  CRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLEECA 479
              +              D DE  + +  E+ Q  S P   RE+   +E EV +DSL+ C 
Sbjct: 3554 LAV--------------DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCY 3599

Query: 480  ITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEE 539
             T S      D  QP+     + EE  +   L               +   + D EEEE+
Sbjct: 3600 STPSGYLELPDLGQPYSSAVYSLEEQYLGLAL--------------DVDRTKKDQEEEED 3645

Query: 540  KGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMA 596
            +GP  P   R L E  E EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  +
Sbjct: 3646 QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFS 3705

Query: 597  VDIG-------------------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQD 637
            +D+G                   R R  +  +EDQ    PRLSRELLDEKGPEV QDS D
Sbjct: 3706 LDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLD 3765

Query: 638  RCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMD 675
            RCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLA+DMD
Sbjct: 3766 RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 3803



 Score = 38.5 bits (88), Expect = 0.12
 Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 3/85 (3%)

Query: 169  DEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225
            D DE  + +E E+  + S PR   E+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 3557 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3616

Query: 226  NIKITFEEDEVNSTLVVDRESSHDE 250
            +   + EE  +   L VDR     E
Sbjct: 3617 SAVYSLEEQYLGLALDVDRTKKDQE 3641


>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
          Length = 942

 Score = 1721 bits (4457), Expect = 0.0
 Identities = 866/919 (94%), Positives = 883/919 (96%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPWSSEKAEMNILEINE LRPQLAE KQQF NLKE+CFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120

Query: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
           RSL EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEE E
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180

Query: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KVLES APREVQKAEESKV EDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL
Sbjct: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA
Sbjct: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300

Query: 301 EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
           EKKQQFRNLKEKCFLTQL+GFLANQQ KYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA
Sbjct: 301 EKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360

Query: 361 EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420
           EELRQYKVLVHAQERELTQL+EKLREGRDASRSLNEHLQALLTP EPDKSQGQDLQEQLA
Sbjct: 361 EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 420

Query: 421 EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
           EGCRLAQHLVQKLSPENDNDD+EDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
Sbjct: 421 EGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480

Query: 481 TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 540
           TYSNSHG YDSNQPHRKTKITFEEDKVDSTLIGSSSHVE EDAVHIIPENESDDEEEEEK
Sbjct: 481 TYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEK 540

Query: 541 GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG 600
           GPVSPRNLQESEEEEVPQESWDEGYST SIPPEMLASY+SYSSTFHSLEEQQVCMAVDIG
Sbjct: 541 GPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG 600

Query: 601 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAF 660
           RHRWDQVKKEDQEATGPRLSRELLDEKGPEV QDS  RCYSTPSGCLELTDSCQPYRSAF
Sbjct: 601 RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAF 660

Query: 661 YILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 720
           Y+LEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSG
Sbjct: 661 YVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSG 720

Query: 721 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780
           Y ELPDLGQPYSSAVYSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPE
Sbjct: 721 YPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780

Query: 781 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840
           VLQDSLDRCYSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
Sbjct: 781 VLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840

Query: 841 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY 900
           SKKERRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q Y
Sbjct: 841 SKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHY 900

Query: 901 RSAFYVLEQQRVGFAVDMD 919
           RS FY  E+Q + FA+ +D
Sbjct: 901 RSVFYSFEEQHISFALYVD 919



 Score = 1014 bits (2622), Expect = 0.0
 Identities = 583/954 (61%), Positives = 659/954 (69%), Gaps = 97/954 (10%)

Query: 272  MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKY 331
            MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF NLKE+CFLTQL+GFLAN+QKKYKY
Sbjct: 1    MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60

Query: 332  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDAS 391
            EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLKEKLREGRDAS
Sbjct: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120

Query: 392  RSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 451
            RSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE  E
Sbjct: 121  RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180

Query: 452  KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511
            KV +S APRE+QKAEE +V EDSLEECAIT SNSHG  DSNQPH+  KITFEED+V+STL
Sbjct: 181  KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 512  I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 569
            +    SSH E +DA++I+P            GP S            P  S     + L 
Sbjct: 241  VVDRESSHDECQDALNILPV----------PGPTSSATNVSMVVSAGPLSSEKAEMNILE 290

Query: 570  IPPEMLASYQSYSSTFHSLEEQQVC------MAVDIGRHRWDQVK-------------KE 610
            I  ++          F +L+E+         +A    ++++++ K             KE
Sbjct: 291  INEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKE 350

Query: 611  DQEATGPRLSRELLDEKG------------PEVFQDSQDRCYSTPSGCLELTDSCQPYRS 658
            ++ A   + + EL   K              E  ++ +D   S       L    +P +S
Sbjct: 351  EKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKS 410

Query: 659  AFYILEQQ-------------RVGLAIDMDEIEKYQE--VEEDQDPSCPRLSRELLDEKE 703
                L++Q             ++    D D+ E  Q    E+ Q  S PR   E+   +E
Sbjct: 411  QGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEE 467

Query: 704  PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALDVDRI------ 752
             EV +DSL+ C  T S      D  QP+     + EE       +G +  V+R       
Sbjct: 468  KEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHII 527

Query: 753  ---KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 809
               + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E   S + Y S+
Sbjct: 528  PENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSST 584

Query: 810  FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLD 869
            F++LEE+ V  ++D+G                   R R  +  +EDQ    PRLSRELLD
Sbjct: 585  FHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGPRLSRELLD 625

Query: 870  EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEE 929
            EKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG AVDMDEIEKYQEVEE
Sbjct: 626  EKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEE 685

Query: 930  DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 989
            DQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGL
Sbjct: 686  DQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGL 745

Query: 990  ALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 1049
            ALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QP
Sbjct: 746  ALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQP 805

Query: 1050 YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 1109
            YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+ 
Sbjct: 806  YGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNG 865

Query: 1110 ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMD 1163
             L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+Q + FA+ +D
Sbjct: 866  VLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919



 Score =  620 bits (1598), Expect = e-176
 Identities = 399/795 (50%), Positives = 469/795 (58%), Gaps = 86/795 (10%)

Query: 1398 QRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELP 1457
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL  C  T S      
Sbjct: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218

Query: 1458 DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDP----PCPR----------- 1502
            D  QP+ +   + EE  +   L VDR     E   DE QD     P P            
Sbjct: 219  DSNQPHKNIKITFEEDEVNSTLVVDR-----ESSHDECQDALNILPVPGPTSSATNVSMV 273

Query: 1503 -----LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSL 1556
                 LS E  E+   E+ +    +            + C     + F A ++N   +  
Sbjct: 274  VSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYE- 332

Query: 1557 DVGEIEKKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLD 1615
               E +   K   R  R+ K+E+   + K+ EE +       ++E    +  E L++  D
Sbjct: 333  ---ECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRD 389

Query: 1616 RCYSTPSGCLELTDSCQPYRSAFYVLEQQ-------------HVGLAVDMDEIEKYQE-- 1660
               S       L    +P +S    L++Q              +    D D+ E  Q   
Sbjct: 390  ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEV 449

Query: 1661 VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ- 1719
             E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE  
Sbjct: 450  AEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDK 506

Query: 1720 ----YLGLALDVDRI---------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDR 1766
                 +G +  V+R          + D EEEE++GP  PR    L E  E EV Q+S D 
Sbjct: 507  VDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDE 563

Query: 1767 CYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRG 1826
             YSTPS   E   S + Y S+F++LEE  V  ++D+G                   R R 
Sbjct: 564  GYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRW 604

Query: 1827 RKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 1886
             +  +EDQ    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLE
Sbjct: 605  DQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLE 664

Query: 1887 QQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 1946
            QQ VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY EL
Sbjct: 665  QQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPEL 724

Query: 1947 PDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 2006
            PDLGQPYSSAVYSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD
Sbjct: 725  PDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 784

Query: 2007 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKE 2066
            SLDRCYSTPSSCLEQPDS QPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKE
Sbjct: 785  SLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 844

Query: 2067 RRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF 2126
            RRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS F
Sbjct: 845  RRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVF 904

Query: 2127 YVLEQQHVGLAVDMD 2141
            Y  E+QH+  A+ +D
Sbjct: 905  YSFEEQHISFALYVD 919



 Score =  619 bits (1595), Expect = e-176
 Identities = 396/784 (50%), Positives = 468/784 (59%), Gaps = 80/784 (10%)

Query: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 167  DEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 2199 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQ-------GPPCPR-----------LSRELL 2240
            +   + EE  +   L VDR +   +E +D        GP               LS E  
Sbjct: 226  NIKITFEEDEVNSTLVVDR-ESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKA 284

Query: 2241 EVVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSLDVGEIEKKGKG 2299
            E+   E+ +    +            + C     + F A ++N   +     E +   K 
Sbjct: 285  EMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYE----ECKDLIKF 340

Query: 2300 KKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 2358
              R  R+ K+E+   + K+ EE +       ++E    +  E L++  D   S       
Sbjct: 341  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 400

Query: 2359 LTDSCQPYRSAFYVLEQQ-------------HVGLAVDMDEIEKYQE--VEEDQDPSCPR 2403
            L    +P +S    L++Q              +    D D+ E  Q    E+ Q  S PR
Sbjct: 401  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR 460

Query: 2404 LSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALD 2458
               E+   +E EV +DSL+ C  T S      D  QP+     + EE       +G +  
Sbjct: 461  ---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSH 517

Query: 2459 VDRI---------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 2509
            V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E 
Sbjct: 518  VEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEM 574

Query: 2510 PDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 2569
              S + Y S+F++LEE  V  ++D+G                   R R  +  +EDQ   
Sbjct: 575  LASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEAT 615

Query: 2570 CPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMD 2629
             PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMD
Sbjct: 616  GPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675

Query: 2630 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 2689
            EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAV
Sbjct: 676  EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAV 735

Query: 2690 YSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 2749
            YSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
Sbjct: 736  YSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 795

Query: 2750 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 2809
            CLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED
Sbjct: 796  CLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 855

Query: 2810 QNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLA 2869
            QNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+QH+  A
Sbjct: 856  QNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 915

Query: 2870 VDMD 2873
            + +D
Sbjct: 916  LYVD 919



 Score =  617 bits (1590), Expect = e-176
 Identities = 395/784 (50%), Positives = 467/784 (59%), Gaps = 80/784 (10%)

Query: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 167  DEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 1711 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQ-------GPPCPR-----------LSRELL 1752
            +   + EE  +   L VDR +   +E +D        GP               LS E  
Sbjct: 226  NIKITFEEDEVNSTLVVDR-ESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKA 284

Query: 1753 EVVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSLDVGEIEKKGKG 1811
            E+   E+ +    +            + C     + F A ++N   +     E +   K 
Sbjct: 285  EMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYE----ECKDLIKF 340

Query: 1812 KKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 1870
              R  R+ K+E+   + K+ EE +       ++E    +  E L++  D   S       
Sbjct: 341  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 400

Query: 1871 LTDSCQPYRSAFYVLEQQ-------------HVGLAVDMDEIEKYQE--VEEDQDPSCPR 1915
            L    +P +S    L++Q              +    D D+ E  Q    E+ Q  S PR
Sbjct: 401  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR 460

Query: 1916 LSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALD 1970
               E+   +E EV +DSL+ C  T S      D  QP+     + EE       +G +  
Sbjct: 461  ---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSH 517

Query: 1971 VDRI---------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 2021
            V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E 
Sbjct: 518  VEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEM 574

Query: 2022 PDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 2081
              S + Y S+F++LEE  V  ++D+G                   R R  +  +EDQ   
Sbjct: 575  LASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEAT 615

Query: 2082 CPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMD 2141
             PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMD
Sbjct: 616  GPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675

Query: 2142 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 2201
            EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAV
Sbjct: 676  EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAV 735

Query: 2202 YSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 2261
            YSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
Sbjct: 736  YSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 795

Query: 2262 CLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 2321
            CLEQPDS QPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED
Sbjct: 796  CLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 855

Query: 2322 QNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLA 2381
            QNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+QH+  A
Sbjct: 856  QNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 915

Query: 2382 VDMD 2385
            + +D
Sbjct: 916  LYVD 919



 Score =  616 bits (1588), Expect = e-175
 Identities = 392/788 (49%), Positives = 466/788 (59%), Gaps = 86/788 (10%)

Query: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 167  DEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 1221 SAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYS- 1279
            +   + EE  +   L VDR   +   +E QD      +  +L V  P     ++    S 
Sbjct: 226  NIKITFEEDEVNSTLVVDR---ESSHDECQD------ALNILPVPGPTSSATNVSMVVSA 276

Query: 1280 -------TPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 1328
                      + LE  +  +P        F  L+EK     L      ++ K K    + 
Sbjct: 277  GPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKD 336

Query: 1329 SKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRCYSTPS 1376
              K   R  ++ +E++     + + EL   K              E L++  D   S   
Sbjct: 337  LIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNE 396

Query: 1377 GCLELTDSCQPYRSAFYVLEQ-------------QRVGMAVDMDEIEKYQ--EVEEDQDP 1421
                L    +P +S    L++             Q++    D D+ E  Q    E+ Q  
Sbjct: 397  HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKS 456

Query: 1422 SCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLG 1476
            S P   RE+   +E EV +DSL  C  T S      D  QP+     + EE       +G
Sbjct: 457  SAP---REMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIG 513

Query: 1477 LALDVDR-------IKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 1529
             +  V+R        + + ++EE+E++ P  P   R L E  E EV Q+S D  YSTPS 
Sbjct: 514  SSSHVEREDAVHIIPENESDDEEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTPSI 570

Query: 1530 CLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 1589
              E   S + Y S+F++LEE  V  ++D+G                   R R  +  +ED
Sbjct: 571  PPEMLASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKED 611

Query: 1590 QNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLA 1649
            Q    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLA
Sbjct: 612  QEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLA 671

Query: 1650 VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 1709
            VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPY
Sbjct: 672  VDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPY 731

Query: 1710 SSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 1769
            SSAVYSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS
Sbjct: 732  SSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYS 791

Query: 1770 TPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1829
            TPSSCLEQPDS QPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE
Sbjct: 792  TPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 851

Query: 1830 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQH 1889
            GEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+QH
Sbjct: 852  GEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQH 911

Query: 1890 VGLAVDMD 1897
            +  A+ +D
Sbjct: 912  ISFALYVD 919



 Score =  613 bits (1582), Expect = e-175
 Identities = 394/784 (50%), Positives = 468/784 (59%), Gaps = 80/784 (10%)

Query: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 167  DEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 2443 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQ-------GPPCPR-----------LSRELL 2484
            +   + EE  +   L VDR +   +E +D        GP               LS E  
Sbjct: 226  NIKITFEEDEVNSTLVVDR-ESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKA 284

Query: 2485 EVVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSLDVGEIEKKGKG 2543
            E+   E+ +    +            + C     + F A ++N   +     E +   K 
Sbjct: 285  EMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYE----ECKDLIKF 340

Query: 2544 KKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 2602
              R  R+ K+E+   + K+ EE +       ++E    +  E L++  D   S       
Sbjct: 341  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 400

Query: 2603 LTDSCQPYRSAFYVLEQQ-------------HVGLAVDMDEIEKYQE--VEEDQDPSCPR 2647
            L    +P +S    L++Q              +    D D+ E  Q    E+ Q  S PR
Sbjct: 401  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR 460

Query: 2648 LSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ-----YLGLALD 2702
               E+   +E EV +DSL+ C  T S      D  QP+     + EE       +G +  
Sbjct: 461  ---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSH 517

Query: 2703 VDRI---------KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 2753
            V+R          + D EEEE++GP  PR    L E  E EV Q+S D  YSTPS   E 
Sbjct: 518  VEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTPSIPPEM 574

Query: 2754 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 2813
              S + Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ   
Sbjct: 575  LASYKSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEAT 615

Query: 2814 CPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMD 2873
             PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVLEQQ VGLAVDMD
Sbjct: 616  GPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675

Query: 2874 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 2933
            EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAV
Sbjct: 676  EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAV 735

Query: 2934 YSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 2993
            YSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS
Sbjct: 736  YSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 795

Query: 2994 CLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 3053
            CLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED
Sbjct: 796  CLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEED 855

Query: 3054 QNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLA 3113
            QNPPCPRL+  L++ + P+VLQDSLD CYSTPS   EL DS Q YRS FY  E+Q +  A
Sbjct: 856  QNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFA 915

Query: 3114 VDMD 3117
            + +D
Sbjct: 916  LYVD 919



 Score =  605 bits (1560), Expect = e-172
 Identities = 324/468 (69%), Positives = 360/468 (76%), Gaps = 8/468 (1%)

Query: 2969 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 3028
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L +G     
Sbjct: 460  REMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL-IGS---- 514

Query: 3029 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGC 3088
                +R              E EE++ P  PR  +E  +E+ P   Q+S D  YSTPS  
Sbjct: 515  SSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVP---QESWDEGYSTPSIP 571

Query: 3089 LELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEV 3148
             E+  S + Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLSRELLDEKGPEV
Sbjct: 572  PEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631

Query: 3149 LQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSC 3208
            LQDSL RCYSTPSGCLEL DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSC
Sbjct: 632  LQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSC 691

Query: 3209 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 3268
            PRLSRELLDEKEPEVLQDSL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLALD+DR
Sbjct: 692  PRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDR 751

Query: 3269 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 3328
            IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS QPYGSSFY
Sbjct: 752  IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFY 811

Query: 3329 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 3388
            ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ +
Sbjct: 812  ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVE 871

Query: 3389 GPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436
             PEVLQDSLD CYSTPS   EL DS Q YRS FY  E+QH+  A+ +D
Sbjct: 872  EPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 919



 Score =  601 bits (1550), Expect = e-171
 Identities = 330/505 (65%), Positives = 367/505 (72%), Gaps = 39/505 (7%)

Query: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
            D +E  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 440  DDNEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHR 496

Query: 977  SAVYSLEEQ-----YLGLALDVDRI---------KKDQEEEEDQGPPCPRLSRELLEVVE 1022
                + EE       +G +  V+R          + D EEEE++GP  PR    L E  E
Sbjct: 497  KTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 553

Query: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082
             EV Q+S D  YSTPS   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 554  EEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 600

Query: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142
                  R R  +  +EDQ    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQ
Sbjct: 601  ------RHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQ 654

Query: 1143 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202
            PYRSAFYVLEQQRVG AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R 
Sbjct: 655  PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRW 714

Query: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELL 1262
            YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLALD+DRIKKD+EEEEDQ PPCPRLSRELL
Sbjct: 715  YSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELL 774

Query: 1263 EVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322
            EVV PEVLQDSLDRCYSTPSSCLEQPDS QPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 775  EVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 834

Query: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1382
            KRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL 
Sbjct: 835  KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELP 894

Query: 1383 DSCQPYRSAFYVLEQQRVGMAVDMD 1407
            DS Q YRS FY  E+Q +  A+ +D
Sbjct: 895  DSFQHYRSVFYSFEEQHISFALYVD 919



 Score =  570 bits (1470), Expect = e-162
 Identities = 318/528 (60%), Positives = 369/528 (69%), Gaps = 39/528 (7%)

Query: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174
            D +E  + +  E+ Q  S PR   E+   +  EV +DSL+ C  T S      DS QP+R
Sbjct: 440  DDNEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHR 496

Query: 3175 SAFYILEQQRVGLAVD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKE 3220
                  E+ +V   +               + E E   E EE++ P  PR    L + +E
Sbjct: 497  KTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 553

Query: 3221 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 3280
             EV Q+S D  YSTPS   E+    + YSS  +SLEEQ + +A+D+ R + DQ ++EDQ 
Sbjct: 554  EEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 613

Query: 3281 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 3340
               PRLSRELL+   PEVLQDSL RCYSTPS CLE  DSCQPY S+FY LE++ VG ++D
Sbjct: 614  ATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVD 673

Query: 3341 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRC 3400
            + EIEK                    +E EEDQ+P CPRLSRELLDEK PEVLQDSL R 
Sbjct: 674  MDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRW 714

Query: 3401 YSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 3460
            YSTPSG  EL D  QPY SA Y LE+Q++GLA+D+D I+K QE EEDQ P CPRLSRELL
Sbjct: 715  YSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELL 774

Query: 3461 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGK 3520
            +  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV +IEKKGKGK
Sbjct: 775  EVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 834

Query: 3521 KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELP 3580
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEE EVLQDSLD CYSTPSMYFELP
Sbjct: 835  KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELP 894

Query: 3581 DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 3628
            DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQM VIFPQ
Sbjct: 895  DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMEVIFPQ 942



 Score =  561 bits (1446), Expect = e-159
 Identities = 383/856 (44%), Positives = 466/856 (54%), Gaps = 149/856 (17%)

Query: 1897 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1956
            +E+ +Y+ +   Q+       REL   KE   L++  D   S       L    +P  S 
Sbjct: 90   EELRQYKVLVHSQE-------RELTQLKEK--LREGRDASRSLNEHLQALLTPDEPDKSQ 140

Query: 1957 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQG-----------PPCPRLSRELLEVVEP 2001
               L+EQ   G  L    V ++  + +E+ED+             P PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR---EVQKAEES 197

Query: 2002 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGK------- 2054
            +V +DSL+ C  T S+     DS QP+ +     EE+ V  +L V       +       
Sbjct: 198  KVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNI 257

Query: 2055 ----GKKRRGRRSKKERRRGRKEGEEDQNPPC---PRLSRELLDEKGPEVLQDSLDRCYS 2107
                G              G    E+ +        +L  +L ++K  +  ++  ++C+ 
Sbjct: 258  LPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKK--QQFRNLKEKCFL 315

Query: 2108 TP-SGCLELTDSCQPY-----------RSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDP 2155
            T  +G L    +   Y           R+     E++        +E+ +Y+ +   Q+ 
Sbjct: 316  TQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQE- 374

Query: 2156 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLALD 2214
                  REL   +E   L++  D   S       L    +P  S    L+EQ   G  L 
Sbjct: 375  ------RELTQLREK--LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLA 426

Query: 2215 VDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2260
               ++K     D ++ ED         Q    PR   E+ +  E EV +DSL+ C  T S
Sbjct: 427  QHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYS 483

Query: 2261 SCLEQPDSCQPYGSSFYALEENHVGFSL---------------------DVGEIEKKGKG 2299
            +     DS QP+  +    EE+ V  +L                     D  E E+KG  
Sbjct: 484  NSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPV 543

Query: 2300 KKRRGRRSKKE----------------------------------------------RRR 2313
              R  + S++E                                              R R
Sbjct: 544  SPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHR 603

Query: 2314 GRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVL 2373
              +  +EDQ    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLELTDSCQPYRSAFYVL
Sbjct: 604  WDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVL 663

Query: 2374 EQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLE 2433
            EQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL R YSTPSGY E
Sbjct: 664  EQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPE 723

Query: 2434 LPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQ 2493
            LPDLGQPYSSAVYSLEEQYLGLALD+DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQ
Sbjct: 724  LPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQ 783

Query: 2494 DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKK 2553
            DSLDRCYSTPSSCLEQPDS QPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKK
Sbjct: 784  DSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK 843

Query: 2554 ERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSA 2613
            ERRRGRKEGEEDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS 
Sbjct: 844  ERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSV 903

Query: 2614 FYVLEQQHVGLAVDMD 2629
            FY  E+QH+  A+ +D
Sbjct: 904  FYSFEEQHISFALYVD 919



 Score =  424 bits (1089), Expect = e-117
 Identities = 326/855 (38%), Positives = 419/855 (49%), Gaps = 168/855 (19%)

Query: 2629 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2688
            +E+ +Y+ +   Q+       REL   KE   L++  D   S       L    +P  S 
Sbjct: 90   EELRQYKVLVHSQE-------RELTQLKEK--LREGRDASRSLNEHLQALLTPDEPDKSQ 140

Query: 2689 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQG-----------PPCPRLSRELLEVVEP 2733
               L+EQ   G  L    V ++  + +E+ED+             P PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESPAPR---EVQKAEES 197

Query: 2734 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK------- 2786
            +V +DSL+ C  T S+     DS QP+ +     EE  V  +L V       +       
Sbjct: 198  KVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNI 257

Query: 2787 ----GKKRRGRRSKKERRRGRKEGEEDQNPPC---PRLSRELLDEKGPEVLQDSLDRCYS 2839
                G              G    E+ +        +L  +L ++K  +  ++  ++C+ 
Sbjct: 258  LPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKK--QQFRNLKEKCFL 315

Query: 2840 TP-SGCLELTDSCQPY-----------RSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDP 2887
            T  +G L    +   Y           R+     E++        +E+ +Y+ +   Q+ 
Sbjct: 316  TQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQE- 374

Query: 2888 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLALD 2946
                  REL   +E   L++  D   S       L    +P  S    L+EQ   G  L 
Sbjct: 375  ------RELTQLREK--LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLA 426

Query: 2947 VDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2992
               ++K     D ++ ED         Q    PR   E+ +  E EV +DSL+ C  T S
Sbjct: 427  QHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITYS 483

Query: 2993 SCLEQPDSCQPYGSSFYALEEKHVGFSL---------------------DVGEIEKKGKG 3031
            +     DS QP+  +    EE  V  +L                     D  E E+KG  
Sbjct: 484  NSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPENESDDEEEEEKGPV 543

Query: 3032 KKRRGRRSKKE----------------------------------------------RRR 3045
              R  + S++E                                              R R
Sbjct: 544  SPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRHR 603

Query: 3046 GRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVL 3105
              +  +EDQ    PRLSRELLDEKGP+VLQDSL RCYSTPSGCLEL DSCQPYRSAFYVL
Sbjct: 604  WDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVL 663

Query: 3106 EQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 3165
            EQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEK PEVLQDSL R YSTPSG  E
Sbjct: 664  EQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPE 723

Query: 3166 LCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 3225
            L D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQ
Sbjct: 724  LPDLGQPYSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQ 783

Query: 3226 DSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD------------- 3272
            DSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K              
Sbjct: 784  DSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK 843

Query: 3273 ------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 3326
                  +E EEDQ PPCPRL+  L+EV EPEVLQDSLD CYSTPS   E PDS Q Y S 
Sbjct: 844  ERRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSV 903

Query: 3327 FYALEEKHVGFSLDV 3341
            FY+ EE+H+ F+L V
Sbjct: 904  FYSFEEQHISFALYV 918



 Score =  359 bits (922), Expect = 2e-98
 Identities = 262/674 (38%), Positives = 330/674 (48%), Gaps = 143/674 (21%)

Query: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107
            +E E+    P PR   E+   +  KV +DSL+ C  T S     CDS QP+++     E+
Sbjct: 177  EEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEE 233

Query: 3108 QRVGLAVDMDEIEKYQEVEEDQD------PSCPRLSRELLDEKGP-----------EVLQ 3150
              V   + +D    + E ++  +      P+    +  ++   GP           E+ +
Sbjct: 234  DEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINE 293

Query: 3151 DSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPR 3210
                +          L + C   + A ++  QQ      +  ++ K+    E Q     +
Sbjct: 294  KLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEECKDLIKFMLRNERQFKE-EK 352

Query: 3211 LSRELLDEKE------------------PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 3252
            L+ +L   +E                   E L++  D   S       L    +P  S  
Sbjct: 353  LAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQG 412

Query: 3253 YSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPE 3297
              L+EQ   G  L    ++K     D ++ ED         Q    P   RE+ +  E E
Sbjct: 413  QDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAP---REMQKAEEKE 469

Query: 3298 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL------------------ 3339
            V +DSL+ C  T S+     DS QP+  +    EE  V  +L                  
Sbjct: 470  VPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEREDAVHIIPE 529

Query: 3340 ---DVGEIEKKGKGKKRRGRRSKKE----------------------------------- 3361
               D  E E+KG    R  + S++E                                   
Sbjct: 530  NESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEMLASYKSYSSTFHSLE 589

Query: 3362 -----------RRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL 3410
                       R R  +  +EDQ    PRLSRELLDEKGPEVLQDSL RCYSTPSGCLEL
Sbjct: 590  EQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLEL 649

Query: 3411 CDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 3470
             DSCQPYRSAFYVLEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD
Sbjct: 650  TDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 709

Query: 3471 SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKE 3530
            SL R YSTPSGY ELPDLGQPYSSAVYSLEEQYLGLALD+D+I+K               
Sbjct: 710  SLGRWYSTPSGYPELPDLGQPYSSAVYSLEEQYLGLALDLDRIKKD-------------- 755

Query: 3531 RRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVF 3590
                 +E EEDQ PPCPRL+  L+EV E EVLQDSLDRCYSTPS   E PDS+Q Y S F
Sbjct: 756  -----QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSF 810

Query: 3591 YSFEEQHISFALYV 3604
            Y+ EE+H+ F+L V
Sbjct: 811  YALEEKHVGFSLDV 824



 Score = 78.2 bits (191), Expect = 1e-13
 Identities = 124/521 (23%), Positives = 190/521 (36%), Gaps = 103/521 (19%)

Query: 3183 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 3242
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      
Sbjct: 160  QKLSPENDEDEDEDVQ-VEEDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPC 218

Query: 3243 DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG---PPCPRLSRELLEVVEPEVL 3299
            D  QP+ +   + EE  +   L VDR     E ++       P P  S   + +V     
Sbjct: 219  DSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGP 278

Query: 3300 QDSLDRCYSTPSSCLEQPDSCQPY----GSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3355
              S         + LE  +  +P        F  L+EK     L      ++ K K    
Sbjct: 279  LSS----EKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKYEEC 334

Query: 3356 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG------------PEVLQDSLDRCYST 3403
            +   K   R  ++ +E++     + + EL   K              E L++  D   S 
Sbjct: 335  KDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSL 394

Query: 3404 PSGCLELCDSCQPYRSAFYVLEQQHV-GLAVDMDEIEKYQEVEEDQDPSCPRLS------ 3456
                  L    +P +S    L++Q   G  +    ++K     ++ D    ++       
Sbjct: 395  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQ 454

Query: 3457 -----RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL--- 3508
                 RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L   
Sbjct: 455  KSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGS 514

Query: 3509 ------------------DVDKIEKKGKGKKRRGRRSKKE-------------------- 3530
                              D ++ E+KG    R  + S++E                    
Sbjct: 515  SSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTPSIPPEM 574

Query: 3531 --------------------------RRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQD 3564
                                      R R  +  +EDQ    PRL+  L++ +  EVLQD
Sbjct: 575  LASYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQD 634

Query: 3565 SLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVD 3605
            SL RCYSTPS   EL DS Q YRS FY  E+Q +  A+ +D
Sbjct: 635  SLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMD 675



 Score = 32.7 bits (73), Expect = 6.7
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 1094 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 1153
            +E E+    P PR   E+   +  +V +DSL+ C  T S      DS QP+++     E+
Sbjct: 177  EEDEKVLESPAPR---EVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEE 233

Query: 1154 QRVGFAVDMDEIEKYQEVEE 1173
              V   + +D    + E ++
Sbjct: 234  DEVNSTLVVDRESSHDECQD 253


>gi|92110019 hypothetical protein LOC55672 [Homo sapiens]
          Length = 1214

 Score = 1702 bits (4408), Expect = 0.0
 Identities = 856/920 (93%), Positives = 878/920 (95%), Gaps = 1/920 (0%)

Query: 1    MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
            MVVSAGP SSEKAEMNILE+NE LRPQLAEKKQQFRNLKEKCF+TQLAGFLAN+Q KYKY
Sbjct: 272  MVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKY 331

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
            EEC+DLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 332  EECEDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 391

Query: 121  RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
            RSL +HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE
Sbjct: 392  RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 451

Query: 181  KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
            KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNI ITFEED+VNS L
Sbjct: 452  KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 511

Query: 241  VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
            VVDRESSHDECQDA+NILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE+NEKLRPQLA
Sbjct: 512  VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLA 571

Query: 301  EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
            EKKQQFRNLKEKCF+TQL+ FLANQQ KYKYEECKDLIK +LRNERQFKEEKLAEQLKQA
Sbjct: 572  EKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQA 631

Query: 361  EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420
            EELRQYKVLVH+QERELTQL+EKLREGRDASRSLN+HLQALLTP EPDKSQGQDLQEQLA
Sbjct: 632  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLA 691

Query: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            EGCRLAQ L QKLSPENDND DEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI
Sbjct: 692  EGCRLAQQLFQKLSPENDNDHDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 751

Query: 481  TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 540
            T SNSHG YDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK
Sbjct: 752  TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 811

Query: 541  GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG 600
            GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYS TFHSLEEQQVCMAVDIG
Sbjct: 812  GPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIG 871

Query: 601  RHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAF 660
             HRWDQVKKEDQEATGPRLSRELLDEKGPEV QDS DRCYSTPSG LELTDSCQPYRSAF
Sbjct: 872  GHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAF 931

Query: 661  YILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 720
            YILEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG
Sbjct: 932  YILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 991

Query: 721  YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 780
            YLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLE VEPE
Sbjct: 992  YLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPE 1051

Query: 781  VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 840
            VLQDSLDRCYSTPSSCLEQPDSC PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR
Sbjct: 1052 VLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 1111

Query: 841  S-KKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQP 899
            S KK RRRGRKEGEEDQNPPCPRLS  L++ + PEVLQDSLDRCYSTPS   EL DS Q 
Sbjct: 1112 STKKRRRRGRKEGEEDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQH 1171

Query: 900  YRSAFYVLEQQRVGFAVDMD 919
            YRS FY  E+Q + FA+D+D
Sbjct: 1172 YRSVFYSFEEQHISFALDVD 1191



 Score = 1540 bits (3986), Expect = 0.0
 Identities = 846/1226 (69%), Positives = 928/1226 (75%), Gaps = 98/1226 (7%)

Query: 1    MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
            MVVSAGPWSSEKAE NILEINE LRPQLAE KQQFRNLKEKCF+TQLAGFLANRQKKYKY
Sbjct: 1    MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKY 60

Query: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
            EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121  RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
            RSL +HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE
Sbjct: 121  RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181  KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
            KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNI ITFEED+VNSTL
Sbjct: 181  KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTL 240

Query: 241  VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
            VVDRESSHDECQDA+NILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE+NEKLRPQLA
Sbjct: 241  VVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLA 300

Query: 301  EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
            EKKQQFRNLKEKCF+TQL+GFLANQQ KYKYEEC+DLIK MLRNERQFKEEKLAEQLKQA
Sbjct: 301  EKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECEDLIKSMLRNERQFKEEKLAEQLKQA 360

Query: 361  EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420
            EELRQYKVLVH+QERELTQL+EKLREGRDASRSLN+HLQALLTP EPDKSQGQDLQEQLA
Sbjct: 361  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLA 420

Query: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            EGCRLAQHLVQKLSPEND D+DEDVQVE AEKV +SSAPRE+QKAEE +VPEDSLEECAI
Sbjct: 421  EGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAI 480

Query: 481  TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 538
            T SNSHG  DSNQPH+   ITFEEDKV+S L+    SSH E +DAV+I+P          
Sbjct: 481  TCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILP---------- 530

Query: 539  EKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEE-----QQV 593
              GP S            P  S     + L +  ++          F +L+E     Q  
Sbjct: 531  VPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLA 590

Query: 594  C-MAVDIGRHRWDQVK-------------KEDQEATGPRLSRELLDEKG----------- 628
            C +A    ++++++ K             KE++ A   + + EL   K            
Sbjct: 591  CFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ 650

Query: 629  -PEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQ-----RVGLAI---------- 672
              E  ++ +D   S       L    +P +S    L++Q     R+   +          
Sbjct: 651  LREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDN 710

Query: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732
            D DE  + +  E+ Q  S P   RE+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 711  DHDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 767

Query: 733  SAVYSLEEQYLGLAL--------------DVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778
                + EE  +   L               +   + D EEEE++GP  P   R L E  E
Sbjct: 768  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSP---RNLQESEE 824

Query: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838
             EV Q+S D  YST S   E   S Q Y  +F++LEE+ V  ++D+G            G
Sbjct: 825  EEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIG------------G 872

Query: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898
             R  + ++       EDQ    PRLSRELLDEKGPEVLQDSLDRCYSTPSG LELTDSCQ
Sbjct: 873  HRWDQVKK-------EDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQ 925

Query: 899  PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
            PYRSAFY+LEQQRVG+A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 926  PYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 985

Query: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018
            YSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 986  YSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1045

Query: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078
            E VEPEVLQDSLDRCYSTPSSCLEQPDSC PYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 1046 EAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1105

Query: 1079 KRRGRRS-KKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL 1137
            KRRGRRS KK RRRGRKEGEEDQNPPCPRLS  L++ + PEVLQDSLDRCYSTPS   EL
Sbjct: 1106 KRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFEL 1165

Query: 1138 TDSCQPYRSAFYVLEQQRVGFAVDMD 1163
             DS Q YRS FY  E+Q + FA+D+D
Sbjct: 1166 PDSFQHYRSVFYSFEEQHISFALDVD 1191



 Score = 1027 bits (2656), Expect = 0.0
 Identities = 632/1243 (50%), Positives = 747/1243 (60%), Gaps = 159/1243 (12%)

Query: 272  MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKY 331
            MVVSAGP SSEKAE NILEINEKLRPQLAE KQQFRNLKEKCF+TQL+GFLAN+QKKYKY
Sbjct: 1    MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKY 60

Query: 332  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDAS 391
            EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDAS
Sbjct: 61   EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 392  RSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 451
            RSLN+HLQALLTP EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121  RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 452  KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511
            KV +SSAPRE+QKAEE +VPEDSLEECAIT SNSHG  DSNQPH+   ITFEEDKV+STL
Sbjct: 181  KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTL 240

Query: 512  I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 569
            +    SSH E +DAV+I+P            GP S            P  S     + L 
Sbjct: 241  VVDRESSHDECQDAVNILPV----------PGPTSSATNVSMVVSAGPLSSEKAEMNILE 290

Query: 570  IPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKK------EDQEATGPRLSREL 623
            +  ++          F +L+E+  C    +     +Q  K      ED   +  R  R+ 
Sbjct: 291  MNEKLRPQLAEKKQQFRNLKEK--CFVTQLAGFLANQQNKYKYEECEDLIKSMLRNERQF 348

Query: 624  LDEKGPEVFQDSQDR------CYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAI----- 672
             +EK  E  + +++        +S      +L +  +  R A   L Q    L       
Sbjct: 349  KEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPD 408

Query: 673  -------------------------------DMDEIEKYQEVEEDQDPSCPRLSRELLDE 701
                                           D DE  + +E E+  + S PR   E+   
Sbjct: 409  KSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR---EVQKA 465

Query: 702  KEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE- 760
            +E +V +DSL+ C  T S      D  QP+ +   + EE  +  AL VDR     E ++ 
Sbjct: 466  EESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDA 525

Query: 761  --------------------DQGPPCPRLSR----ELLEVVEPEVLQDSL------DRCY 790
                                  GP     +     E+ E + P++ +         ++C+
Sbjct: 526  VNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCF 585

Query: 791  STPSSCL-----------EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 839
             T  +C            E  D  +    +    +E+ +   L   E  ++ K       
Sbjct: 586  VTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQE 645

Query: 840  RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQP 899
            R   + R   +EG +        L   L  ++  +     L           +L + C+ 
Sbjct: 646  RELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQE---------QLAEGCRL 696

Query: 900  YRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCY 959
             +  F  L  +      D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C 
Sbjct: 697  AQQLFQKLSPENDN---DHDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECA 750

Query: 960  STPSGYLELPDLGQPYSSAVYSLEEQYLGLALD--------------VDRIKKDQEEEED 1005
             T S      D  QP+     + EE  +   L               +   + D EEEE+
Sbjct: 751  ITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEE 810

Query: 1006 QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFS 1065
            +GP  PR    L E  E EV Q+S D  YST S   E   S Q Y  +F++LEE+ V  +
Sbjct: 811  KGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMA 867

Query: 1066 LDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLD 1125
            +D+G            G R  + ++       EDQ    PRLSRELLDEKGPEVLQDSLD
Sbjct: 868  VDIG------------GHRWDQVKK-------EDQEATGPRLSRELLDEKGPEVLQDSLD 908

Query: 1126 RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRE 1185
            RCYSTPSG LELTDSCQPYRSAFY+LEQQRVG+A+DMDEIEKYQEVEEDQDPSCPRLSRE
Sbjct: 909  RCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRE 968

Query: 1186 LLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEE 1245
            LLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKD+E
Sbjct: 969  LLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQE 1028

Query: 1246 EEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKH 1305
            EEEDQ PPCPRLSRELLE V PEVLQDSLDRCYSTPSSCLEQPDSC PYGSSFYALEEKH
Sbjct: 1029 EEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKH 1088

Query: 1306 VGFSLDVGEIEKKGKGKKRRGRRS-KKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVL 1364
            VGFSLDVGEIEKKGKGKKRRGRRS KK RRRGRKEGEEDQNPPCPRLS  L++ + PEVL
Sbjct: 1089 VGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGMLMEVEEPEVL 1148

Query: 1365 QDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDMD 1407
            QDSLDRCYSTPS   EL DS Q YRS FY  E+Q +  A+D+D
Sbjct: 1149 QDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVD 1191



 Score =  637 bits (1643), Expect = 0.0
 Identities = 456/1078 (42%), Positives = 564/1078 (52%), Gaps = 152/1078 (14%)

Query: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220
            D DE  + +E E+  + S PR   E+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 169  DEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 1221 SAVYSLEEQYLGLALDVDRIKKDEEEEEDQDP------PCPRLSRELLEVVAPEVLQDSL 1274
            +   + EE  +   L VDR   +   +E QD       P P  S   + +V       S 
Sbjct: 226  NINITFEEDKVNSTLVVDR---ESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSS- 281

Query: 1275 DRCYSTPSSCLEQPDSCQPY----GSSFYALEEKH-----VGFSLD------VGEIEKKG 1319
                    + LE  +  +P        F  L+EK       GF  +        E E   
Sbjct: 282  ---EKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECEDLI 338

Query: 1320 KGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 1378
            K   R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S     
Sbjct: 339  KSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHL 398

Query: 1379 LELTDSCQPYRSAFYVLEQQ-------------RVGMAVDMDEIEKYQ--EVEEDQDPSC 1423
              L    +P +S    L++Q             ++    D DE E  Q  E E+  + S 
Sbjct: 399  QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSA 458

Query: 1424 PRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 1483
            PR   E+   +E +V +DSL  C  T S      D  QP+ +   + EE  +  AL VDR
Sbjct: 459  PR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDR 515

Query: 1484 IKKDQEEEEDEDQDP------PCPRLSR----------------------ELLEVVEPEV 1515
                 E   DE QD       P P  S                       E+ E + P++
Sbjct: 516  -----ESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQL 570

Query: 1516 LQDSL------DRCYSTPSSCL-----------EQPDSCQPYGSSFYALEENHVGFSLDV 1558
             +         ++C+ T  +C            E  D  +    +    +E  +   L  
Sbjct: 571  AEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQ 630

Query: 1559 GEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCY 1618
             E  ++ K       R   + R   +EG +        L   L  ++  +     L    
Sbjct: 631  AEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQE-- 688

Query: 1619 STPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 1678
                   +L + C+  +  F  L  ++     D DE  + +  E+ Q  S PR   E+  
Sbjct: 689  -------QLAEGCRLAQQLFQKLSPENDN---DHDEDVQVEVAEKVQKSSAPR---EMQK 735

Query: 1679 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD------------ 1726
             +E EV +DSL+ C  T S      D  QP+     + EE  +   L             
Sbjct: 736  AEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAV 795

Query: 1727 --VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1784
              +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   S Q Y
Sbjct: 796  HIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSY 852

Query: 1785 GSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRE 1844
              +F++LEE  V  ++D+G            G R  + ++       EDQ    PRLSRE
Sbjct: 853  SGTFHSLEEQQVCMAVDIG------------GHRWDQVKK-------EDQEATGPRLSRE 893

Query: 1845 LLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQE 1904
            LLDEKGPEVLQDSLDRCYSTPSG LELTDSCQPYRSAFY+LEQQ VG A+DMDEIEKYQE
Sbjct: 894  LLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQE 953

Query: 1905 VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 1964
            VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY SAVYSLEEQY
Sbjct: 954  VEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQY 1013

Query: 1965 LGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS 2024
            LGLALDVDRIKKDQEEEEDQGPPCPRLSRELLE VEPEVLQDSLDRCYSTPSSCLEQPDS
Sbjct: 1014 LGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDS 1073

Query: 2025 CQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRS-KKERRRGRKEGEEDQNPPCP 2083
            C PYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRS KK RRRGRKEGEEDQNPPCP
Sbjct: 1074 CLPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCP 1133

Query: 2084 RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMD 2141
            RLS  L++ + PEVLQDSLDRCYSTPS   EL DS Q YRS FY  E+QH+  A+D+D
Sbjct: 1134 RLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVD 1191



 Score =  635 bits (1638), Expect = 0.0
 Identities = 453/1100 (41%), Positives = 573/1100 (52%), Gaps = 149/1100 (13%)

Query: 1380 ELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1439
            +L + C   R A +++++       D DE  + +E E+  + S PR   E+   +E +V 
Sbjct: 147  QLAEGC---RLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR---EVQKAEESKVP 200

Query: 1440 QDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDP- 1498
            +DSL  C  T S      D  QP+ +   + EE  +   L VDR     E   DE QD  
Sbjct: 201  EDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTLVVDR-----ESSHDECQDAV 255

Query: 1499 ---PCPR----------------LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC-Q 1538
               P P                 LS E  E+   E+ +    +            + C  
Sbjct: 256  NILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFV 315

Query: 1539 PYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRL 1597
               + F A ++N   +     E E   K   R  R+ K+E+   + K+ EE +       
Sbjct: 316  TQLAGFLANQQNKYKYE----ECEDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVH 371

Query: 1598 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ---------HVGL 1648
            S+E    +  E L++  D   S       L    +P +S    L++Q         H+  
Sbjct: 372  SQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQ 431

Query: 1649 AV------DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 1702
             +      D DE  + +E E+  + S PR   E+   +E +V +DSL+ C  T S     
Sbjct: 432  KLSPENDEDEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGP 488

Query: 1703 PDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQG 1741
             D  QP+ +   + EE  +  AL VDR     E ++                       G
Sbjct: 489  CDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAG 548

Query: 1742 PPCPRLSR----ELLEVVEPEVLQDSL------DRCYSTPSSCL-----------EQPDS 1780
            P     +     E+ E + P++ +         ++C+ T  +C            E  D 
Sbjct: 549  PLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDL 608

Query: 1781 CQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPR 1840
             +    +    +E  +   L   E  ++ K       R   + R   +EG +        
Sbjct: 609  IKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQH 668

Query: 1841 LSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 1900
            L   L  ++  +     L           +L + C+  +  F  L  ++     D DE  
Sbjct: 669  LQALLTPDEPDKSQGQDLQE---------QLAEGCRLAQQLFQKLSPENDN---DHDEDV 716

Query: 1901 KYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSL 1960
            + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+     + 
Sbjct: 717  QVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITF 773

Query: 1961 EEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 2006
            EE  +   L               +   + D EEEE++GP  PR    L E  E EV Q+
Sbjct: 774  EEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQE 830

Query: 2007 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKE 2066
            S D  YST S   E   S Q Y  +F++LEE  V  ++D+G            G R  + 
Sbjct: 831  SWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIG------------GHRWDQV 878

Query: 2067 RRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAF 2126
            ++       EDQ    PRLSRELLDEKGPEVLQDSLDRCYSTPSG LELTDSCQPYRSAF
Sbjct: 879  KK-------EDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAF 931

Query: 2127 YVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 2186
            Y+LEQQ VG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG
Sbjct: 932  YILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSG 991

Query: 2187 YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPE 2246
            YLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLE VEPE
Sbjct: 992  YLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPE 1051

Query: 2247 VLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRR 2306
            VLQDSLDRCYSTPSSCLEQPDSC PYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRR
Sbjct: 1052 VLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRR 1111

Query: 2307 S-KKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQP 2365
            S KK RRRGRKEGEEDQNPPCPRLS  L++ + PEVLQDSLDRCYSTPS   EL DS Q 
Sbjct: 1112 STKKRRRRGRKEGEEDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQH 1171

Query: 2366 YRSAFYVLEQQHVGLAVDMD 2385
            YRS FY  E+QH+  A+D+D
Sbjct: 1172 YRSVFYSFEEQHISFALDVD 1191



 Score =  634 bits (1636), Expect = 0.0
 Identities = 446/1070 (41%), Positives = 562/1070 (52%), Gaps = 138/1070 (12%)

Query: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954
            D DE  + +E E+  + S PR   E+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 169  DEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 1955 SAVYSLEEQYLGLALDVDRIKKDQEEEED------QGPPCPR-----------LSRELLE 1997
            +   + EE  +   L VDR     E ++        GP               LS E  E
Sbjct: 226  NINITFEEDKVNSTLVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAE 285

Query: 1998 VVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2056
            +   E+ +    +            + C     + F A ++N   +     E E   K  
Sbjct: 286  MNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYE----ECEDLIKSM 341

Query: 2057 KRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL 2115
             R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S       L
Sbjct: 342  LRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQAL 401

Query: 2116 TDSCQPYRSAFYVLEQQ---------HVGLAV------DMDEIEKYQEVEEDQDPSCPRL 2160
                +P +S    L++Q         H+   +      D DE  + +E E+  + S PR 
Sbjct: 402  LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR- 460

Query: 2161 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 2220
              E+   +E +V +DSL+ C  T S      D  QP+ +   + EE  +  AL VDR   
Sbjct: 461  --EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESS 518

Query: 2221 DQEEEE---------------------DQGPPCPRLSR----ELLEVVEPEVLQDSL--- 2252
              E ++                       GP     +     E+ E + P++ +      
Sbjct: 519  HDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFR 578

Query: 2253 ---DRCYSTPSSCL-----------EQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGK 2298
               ++C+ T  +C            E  D  +    +    +E  +   L   E  ++ K
Sbjct: 579  NLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYK 638

Query: 2299 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 2358
                   R   + R   +EG +        L   L  ++  +     L           +
Sbjct: 639  VLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQE---------Q 689

Query: 2359 LTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 2418
            L + C+  +  F  L  ++     D DE  + +  E+ Q  S PR   E+   +E EV +
Sbjct: 690  LAEGCRLAQQLFQKLSPENDN---DHDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPE 743

Query: 2419 DSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD--------------VDRIKK 2464
            DSL+ C  T S      D  QP+     + EE  +   L               +   + 
Sbjct: 744  DSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENES 803

Query: 2465 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2524
            D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   S Q Y  +F++LE
Sbjct: 804  DDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLE 860

Query: 2525 ENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 2584
            E  V  ++D+G            G R  + ++       EDQ    PRLSRELLDEKGPE
Sbjct: 861  EQQVCMAVDIG------------GHRWDQVKK-------EDQEATGPRLSRELLDEKGPE 901

Query: 2585 VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPS 2644
            VLQDSLDRCYSTPSG LELTDSCQPYRSAFY+LEQQ VG A+DMDEIEKYQEVEEDQDPS
Sbjct: 902  VLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPS 961

Query: 2645 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2704
            CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVD
Sbjct: 962  CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD 1021

Query: 2705 RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 2764
            RIKKDQEEEEDQGPPCPRLSRELLE VEPEVLQDSLDRCYSTPSSCLEQPDSC PYGSSF
Sbjct: 1022 RIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSF 1081

Query: 2765 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRS-KKERRRGRKEGEEDQNPPCPRLSRELLD 2823
            YALEEKHVGFSLDVGEIEKKGKGKKRRGRRS KK RRRGRKEGEEDQNPPCPRLS  L++
Sbjct: 1082 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGMLME 1141

Query: 2824 EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMD 2873
             + PEVLQDSLDRCYSTPS   EL DS Q YRS FY  E+QH+  A+D+D
Sbjct: 1142 VEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVD 1191



 Score =  629 bits (1623), Expect = e-179
 Identities = 444/1070 (41%), Positives = 562/1070 (52%), Gaps = 138/1070 (12%)

Query: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
            D DE  + +E E+  + S PR   E+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 169  DEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 2199 SAVYSLEEQYLGLALDVDRIKKDQEEEED------QGPPCPR-----------LSRELLE 2241
            +   + EE  +   L VDR     E ++        GP               LS E  E
Sbjct: 226  NINITFEEDKVNSTLVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAE 285

Query: 2242 VVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2300
            +   E+ +    +            + C     + F A ++N   +     E E   K  
Sbjct: 286  MNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYE----ECEDLIKSM 341

Query: 2301 KRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL 2359
             R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S       L
Sbjct: 342  LRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQAL 401

Query: 2360 TDSCQPYRSAFYVLEQQ---------HVGLAV------DMDEIEKYQEVEEDQDPSCPRL 2404
                +P +S    L++Q         H+   +      D DE  + +E E+  + S PR 
Sbjct: 402  LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR- 460

Query: 2405 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 2464
              E+   +E +V +DSL+ C  T S      D  QP+ +   + EE  +  AL VDR   
Sbjct: 461  --EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESS 518

Query: 2465 DQEEEE---------------------DQGPPCPRLSR----ELLEVVEPEVLQDSL--- 2496
              E ++                       GP     +     E+ E + P++ +      
Sbjct: 519  HDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFR 578

Query: 2497 ---DRCYSTPSSCL-----------EQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGK 2542
               ++C+ T  +C            E  D  +    +    +E  +   L   E  ++ K
Sbjct: 579  NLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYK 638

Query: 2543 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 2602
                   R   + R   +EG +        L   L  ++  +     L           +
Sbjct: 639  VLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQE---------Q 689

Query: 2603 LTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 2662
            L + C+  +  F  L  ++     D DE  + +  E+ Q  S PR   E+   +E EV +
Sbjct: 690  LAEGCRLAQQLFQKLSPENDN---DHDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPE 743

Query: 2663 DSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD--------------VDRIKK 2708
            DSL+ C  T S      D  QP+     + EE  +   L               +   + 
Sbjct: 744  DSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENES 803

Query: 2709 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 2768
            D EEEE++GP  PR    L E  E EV Q+S D  YST S   E   S Q Y  +F++LE
Sbjct: 804  DDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLE 860

Query: 2769 EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 2828
            E+ V  ++D+G            G R  + ++       EDQ    PRLSRELLDEKGPE
Sbjct: 861  EQQVCMAVDIG------------GHRWDQVKK-------EDQEATGPRLSRELLDEKGPE 901

Query: 2829 VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPS 2888
            VLQDSLDRCYSTPSG LELTDSCQPYRSAFY+LEQQ VG A+DMDEIEKYQEVEEDQDPS
Sbjct: 902  VLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPS 961

Query: 2889 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 2948
            CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVD
Sbjct: 962  CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD 1021

Query: 2949 RIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 3008
            RIKKDQEEEEDQGPPCPRLSRELLE VEPEVLQDSLDRCYSTPSSCLEQPDSC PYGSSF
Sbjct: 1022 RIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSF 1081

Query: 3009 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRS-KKERRRGRKEGEEDQNPPCPRLSRELLD 3067
            YALEEKHVGFSLDVGEIEKKGKGKKRRGRRS KK RRRGRKEGEEDQNPPCPRLS  L++
Sbjct: 1082 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGMLME 1141

Query: 3068 EKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMD 3117
             + P+VLQDSLDRCYSTPS   EL DS Q YRS FY  E+Q +  A+D+D
Sbjct: 1142 VEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVD 1191



 Score =  629 bits (1621), Expect = e-179
 Identities = 458/1098 (41%), Positives = 583/1098 (53%), Gaps = 119/1098 (10%)

Query: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442
            D DE  + +E E+  + S PR   E+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 169  DEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 2443 SAVYSLEEQYLGLALDVDRIKKDQEEEED------QGPPCPR-----------LSRELLE 2485
            +   + EE  +   L VDR     E ++        GP               LS E  E
Sbjct: 226  NINITFEEDKVNSTLVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAE 285

Query: 2486 VVEPEVLQDSLDRCYSTPSSCLEQPDSC-QPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2544
            +   E+ +    +            + C     + F A ++N   +     E E   K  
Sbjct: 286  MNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYE----ECEDLIKSM 341

Query: 2545 KRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL 2603
             R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S       L
Sbjct: 342  LRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQAL 401

Query: 2604 TDSCQPYRSAFYVLEQQ---------HVGLAV------DMDEIEKYQEVEEDQDPSCPRL 2648
                +P +S    L++Q         H+   +      D DE  + +E E+  + S PR 
Sbjct: 402  LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR- 460

Query: 2649 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 2708
              E+   +E +V +DSL+ C  T S      D  QP+ +   + EE  +  AL VDR   
Sbjct: 461  --EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESS 518

Query: 2709 DQEEEEDQG---PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY----G 2761
              E ++       P P  S   + +V       S         + LE  +  +P      
Sbjct: 519  HDECQDAVNILPVPGPTSSATNVSMVVSAGPLSS----EKAEMNILEMNEKLRPQLAEKK 574

Query: 2762 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2821
              F  L+EK     L      ++ K K    +   K   R  ++ +E+      +L+ +L
Sbjct: 575  QQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEE------KLAEQL 628

Query: 2822 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQ-- 2879
               K  E L+      +S      +L +  +  R A   L Q H+   +  DE +K Q  
Sbjct: 629  ---KQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQ-HLQALLTPDEPDKSQGQ 684

Query: 2880 EVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 2939
            +++E     C RL+++L  +  PE   D                                
Sbjct: 685  DLQEQLAEGC-RLAQQLFQKLSPENDNDH------------------------------- 712

Query: 2940 YLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 2999
                  D D   +  E+ +    P     RE+ +  E EV +DSL+ C  T S+     D
Sbjct: 713  ------DEDVQVEVAEKVQKSSAP-----REMQKAEEKEVPEDSLEECAITCSNSHGPYD 761

Query: 3000 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP 3059
            S QP+  +    EE  V  +L       + +        ++ +      E EE++ P  P
Sbjct: 762  SNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-----DEEEEEKGPVSP 816

Query: 3060 RLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEI 3119
            R  +E  +E+ P   Q+S D  YST S   E+  S Q Y   F+ LE+Q+V +AVD+   
Sbjct: 817  RNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIGGH 873

Query: 3120 EKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYI 3179
               Q  +EDQ+ + PRLSRELLDEKGPEVLQDSLDRCYSTPSG LEL DSCQPYRSAFYI
Sbjct: 874  RWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYI 933

Query: 3180 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 3239
            LEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL
Sbjct: 934  LEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 993

Query: 3240 ELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 3299
            ELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLE VEPEVL
Sbjct: 994  ELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPEVL 1053

Query: 3300 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS- 3358
            QDSLDRCYSTPSSCLEQPDSC PYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 
Sbjct: 1054 QDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRST 1113

Query: 3359 KKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3418
            KK RRRGRKEGEEDQNPPCPRLS  L++ + PEVLQDSLDRCYSTPS   EL DS Q YR
Sbjct: 1114 KKRRRRGRKEGEEDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYR 1173

Query: 3419 SAFYVLEQQHVGLAVDMD 3436
            S FY  E+QH+  A+D+D
Sbjct: 1174 SVFYSFEEQHISFALDVD 1191



 Score =  620 bits (1600), Expect = e-177
 Identities = 446/1072 (41%), Positives = 561/1072 (52%), Gaps = 140/1072 (13%)

Query: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732
            D DE  + +E E+  + S PR   E+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 169  DEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 733  SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG---PPCPRLSRELLEVVEPEVLQDSLDRC 789
            +   + EE  +   L VDR     E ++       P P  S   + +V       S    
Sbjct: 226  NINITFEEDKVNSTLVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSS---- 281

Query: 790  YSTPSSCLEQPDSCQPY----GSSFYALEEKH-----VGFSLD------VGEIEKKGKGK 834
                 + LE  +  +P        F  L+EK       GF  +        E E   K  
Sbjct: 282  EKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECEDLIKSM 341

Query: 835  KRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL 893
             R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S       L
Sbjct: 342  LRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQAL 401

Query: 894  TDSCQPYRSAFYVLEQQ-------------RVGFAVDMDEIEKYQ--EVEEDQDPSCPRL 938
                +P +S    L++Q             ++    D DE E  Q  E E+  + S PR 
Sbjct: 402  LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR- 460

Query: 939  SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 998
              E+   +E +V +DSL+ C  T S      D  QP+ +   + EE  +  AL VDR   
Sbjct: 461  --EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESS 518

Query: 999  DQEEEE---------------------DQGPPCPRLSR----ELLEVVEPEVLQDSL--- 1030
              E ++                       GP     +     E+ E + P++ +      
Sbjct: 519  HDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFR 578

Query: 1031 ---DRCYSTPSSCL-----------EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK 1076
               ++C+ T  +C            E  D  +    +    +E+ +   L   E  ++ K
Sbjct: 579  NLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYK 638

Query: 1077 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 1136
                   R   + R   +EG +        L   L  ++  +     L           +
Sbjct: 639  VLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQE---------Q 689

Query: 1137 LTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 1196
            L + C+  +  F  L  +      D DE  + +  E+ Q  S PR   E+   +E EV +
Sbjct: 690  LAEGCRLAQQLFQKLSPENDN---DHDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPE 743

Query: 1197 DSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD--------------VDRIKK 1242
            DSL+ C  T S      D  QP+     + EE  +   L               +   + 
Sbjct: 744  DSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENES 803

Query: 1243 DEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 1302
            D+EEEE++ P  PR    L E    EV Q+S D  YST S   E   S Q Y  +F++LE
Sbjct: 804  DDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLE 860

Query: 1303 EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPE 1362
            E+ V  ++D+G            G R  + ++       EDQ    PRLSRELLDEKGPE
Sbjct: 861  EQQVCMAVDIG------------GHRWDQVKK-------EDQEATGPRLSRELLDEKGPE 901

Query: 1363 VLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPS 1422
            VLQDSLDRCYSTPSG LELTDSCQPYRSAFY+LEQQRVG A+DMDEIEKYQEVEEDQDPS
Sbjct: 902  VLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPS 961

Query: 1423 CPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 1482
            CPRLSRELLDEKEPEVLQDSL+RCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVD
Sbjct: 962  CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD 1021

Query: 1483 RIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGS 1542
            RIKKDQEEE  EDQ PPCPRLSRELLE VEPEVLQDSLDRCYSTPSSCLEQPDSC PYGS
Sbjct: 1022 RIKKDQEEE--EDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGS 1079

Query: 1543 SFYALEENHVGFSLDVGEIEKKGKGKKRRGRRS-KKERRRGRKEGEEDQNPPCPRLSREL 1601
            SFYALEE HVGFSLDVGEIEKKGKGKKRRGRRS KK RRRGRKEGEEDQNPPCPRLS  L
Sbjct: 1080 SFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGML 1139

Query: 1602 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMD 1653
            ++ + PEVLQDSLDRCYSTPS   EL DS Q YRS FY  E+QH+  A+D+D
Sbjct: 1140 MEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVD 1191



 Score =  586 bits (1511), Expect = e-166
 Identities = 433/1093 (39%), Positives = 564/1093 (51%), Gaps = 138/1093 (12%)

Query: 2627 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2686
            D DE  + +E E+  + S PR   E+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 169  DEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225

Query: 2687 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG---PPCPRLSRELLEVVEPEVLQDSLDRC 2743
            +   + EE  +   L VDR     E ++       P P  S   + +V       S    
Sbjct: 226  NINITFEEDKVNSTLVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSS---- 281

Query: 2744 YSTPSSCLEQPDSCQPY----GSSFYALEEKH-----VGFSLD------VGEIEKKGKGK 2788
                 + LE  +  +P        F  L+EK       GF  +        E E   K  
Sbjct: 282  EKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECEDLIKSM 341

Query: 2789 KRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLEL 2847
             R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S       L
Sbjct: 342  LRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQAL 401

Query: 2848 TDSCQPYRSAFYVLEQQ---------HVGLAV------DMDEIEKYQEVEEDQDPSCPRL 2892
                +P +S    L++Q         H+   +      D DE  + +E E+  + S PR 
Sbjct: 402  LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR- 460

Query: 2893 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 2952
              E+   +E +V +DSL+ C  T S      D  QP+ +   + EE  +  AL VDR   
Sbjct: 461  --EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESS 518

Query: 2953 DQEEEE---------------------DQGPPCPRLSR----ELLEVVEPEVLQDSL--- 2984
              E ++                       GP     +     E+ E + P++ +      
Sbjct: 519  HDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFR 578

Query: 2985 ---DRCYSTPSSCL-----------EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK 3030
               ++C+ T  +C            E  D  +    +    +E+ +   L   E  ++ K
Sbjct: 579  NLKEKCFVTQLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYK 638

Query: 3031 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLE 3090
                   R   + R   +EG +        L   L  ++  K     L           +
Sbjct: 639  VLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQE---------Q 689

Query: 3091 LCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQ 3150
            L + C+  +  F  L  +      D DE  + +  E+ Q  S PR   E+   +  EV +
Sbjct: 690  LAEGCRLAQQLFQKLSPENDN---DHDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPE 743

Query: 3151 DSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVD--------------MDEIEK 3196
            DSL+ C  T S      DS QP+R      E+ +V   +               + E E 
Sbjct: 744  DSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENES 803

Query: 3197 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLE 3256
              E EE++ P  PR    L + +E EV Q+S D  YST S   E+    Q YS   +SLE
Sbjct: 804  DDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLE 860

Query: 3257 EQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 3316
            EQ + +A+D+   + DQ ++EDQ    PRLSRELL+   PEVLQDSLDRCYSTPS  LE 
Sbjct: 861  EQQVCMAVDIGGHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLEL 920

Query: 3317 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 3376
             DSCQPY S+FY LE++ VG++LD+ EIEK                    +E EEDQ+P 
Sbjct: 921  TDSCQPYRSAFYILEQQRVGWALDMDEIEKY-------------------QEVEEDQDPS 961

Query: 3377 CPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436
            CPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPYRSA Y LE+Q++GLA+D+D
Sbjct: 962  CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVD 1021

Query: 3437 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 3496
             I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD   PY S+ 
Sbjct: 1022 RIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSF 1081

Query: 3497 YSLEEQYLGLALDVDKIEKKGKGKKRRGRRS-KKERRRGRKEGEEDQNPPCPRLNGVLME 3555
            Y+LEE+++G +LDV +IEKKGKGKKRRGRRS KK RRRGRKEGEEDQNPPCPRL+G+LME
Sbjct: 1082 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGMLME 1141

Query: 3556 VEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTS 3615
            VEE EVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFAL VDNRF TL  TS
Sbjct: 1142 VEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVDNRFLTLMGTS 1201

Query: 3616 LHLVFQMGVIFPQ 3628
            LHLVFQMGVIFPQ
Sbjct: 1202 LHLVFQMGVIFPQ 1214



 Score =  568 bits (1465), Expect = e-161
 Identities = 435/1146 (37%), Positives = 559/1146 (48%), Gaps = 213/1146 (18%)

Query: 1653 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1712
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPD---------EPDKSQ 140

Query: 1713 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 1760
               L+EQ   G  L    V ++  + +E+ED+                RE+ +  E +V 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVP 200

Query: 1761 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 1820
            +DSL+ C  T S+     DS QP+ +     EE+ V  +L V              R S 
Sbjct: 201  EDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTLVV-------------DRESS 247

Query: 1821 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY-- 1878
             +  +          P     +  ++   GP   +             LE+ +  +P   
Sbjct: 248  HDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSE-------KAEMNILEMNEKLRPQLA 300

Query: 1879 --RSAFYVLEQ-----QHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 1931
              +  F  L++     Q  G   +     KY+E  ED   S  R  R+  +EK  E L+ 
Sbjct: 301  EKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEEC-EDLIKSMLRNERQFKEEKLAEQLKQ 359

Query: 1932 SLD-RCYS--TPSGYLELPDL------------------------GQPYSSAVYSLEEQY 1964
            + + R Y     S   EL  L                         +P  S    L+EQ 
Sbjct: 360  AEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQL 419

Query: 1965 L-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVLQDSLDRCY 2012
              G  L    V ++  + +E+ED+                RE+ +  E +V +DSL+ C 
Sbjct: 420  AEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECA 479

Query: 2013 STPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGK-----------GKKRRGR 2061
             T S+     DS QP+ +     EE+ V  +L V       +           G      
Sbjct: 480  ITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSAT 539

Query: 2062 RSKKERRRGRKEGEEDQN---PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT-- 2116
                    G    E+ +        +L  +L ++K  +  ++  ++C+ T   C      
Sbjct: 540  NVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKK--QQFRNLKEKCFVTQLACFLANQQ 597

Query: 2117 -----DSCQP-----YRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 2166
                 + C+       R+     E++        +E+ +Y+ +   Q+       REL  
Sbjct: 598  NKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQE-------RELTQ 650

Query: 2167 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLALDVDRIKK----- 2220
             +E   L++  D   S       L    +P  S    L+EQ   G  L     +K     
Sbjct: 651  LREK--LREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLFQKLSPEN 708

Query: 2221 DQEEEED---------QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 2271
            D + +ED         Q    P   RE+ +  E EV +DSL+ C  T S+     DS QP
Sbjct: 709  DNDHDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQP 765

Query: 2272 YGSSFYALEENHVGFSL---------------------DVGEIEKKGKGKKRRGRRSKKE 2310
            +  +    EE+ V  +L                     D  E E+KG    R  + S++E
Sbjct: 766  HRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE 825

Query: 2311 R----------------------------------------------RRGRKEGEEDQNP 2324
                                                            R  +  +EDQ  
Sbjct: 826  EVPQESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIGGHRWDQVKKEDQEA 885

Query: 2325 PCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM 2384
              PRLSRELLDEKGPEVLQDSLDRCYSTPSG LELTDSCQPYRSAFY+LEQQ VG A+DM
Sbjct: 886  TGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDM 945

Query: 2385 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2444
            DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY SA
Sbjct: 946  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSA 1005

Query: 2445 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2504
            VYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLE VEPEVLQDSLDRCYSTPS
Sbjct: 1006 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPS 1065

Query: 2505 SCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRS-KKERRRGRKEGE 2563
            SCLEQPDSC PYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRS KK RRRGRKEGE
Sbjct: 1066 SCLEQPDSCLPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGE 1125

Query: 2564 EDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVG 2623
            EDQNPPCPRLS  L++ + PEVLQDSLDRCYSTPS   EL DS Q YRS FY  E+QH+ 
Sbjct: 1126 EDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHIS 1185

Query: 2624 LAVDMD 2629
             A+D+D
Sbjct: 1186 FALDVD 1191



 Score =  404 bits (1038), Expect = e-112
 Identities = 354/1085 (32%), Positives = 489/1085 (45%), Gaps = 188/1085 (17%)

Query: 2629 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2688
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPD---------EPDKSQ 140

Query: 2689 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2736
               L+EQ   G  L    V ++  + +E+ED+                RE+ +  E +V 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVP 200

Query: 2737 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 2796
            +DSL+ C  T S+     DS QP+ +     EE  V  +L V              R S 
Sbjct: 201  EDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTLVV-------------DRESS 247

Query: 2797 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPY-- 2854
             +  +          P     +  ++   GP   +             LE+ +  +P   
Sbjct: 248  HDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSE-------KAEMNILEMNEKLRPQLA 300

Query: 2855 --RSAFYVLEQ-----QHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 2907
              +  F  L++     Q  G   +     KY+E  ED   S  R  R+  +EK  E L+ 
Sbjct: 301  EKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEEC-EDLIKSMLRNERQFKEEKLAEQLKQ 359

Query: 2908 SLD-RCYS--TPSGYLELPDL------------------------GQPYSSAVYSLEEQY 2940
            + + R Y     S   EL  L                         +P  S    L+EQ 
Sbjct: 360  AEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQEQL 419

Query: 2941 L-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVLQDSLDRCY 2988
              G  L    V ++  + +E+ED+                RE+ +  E +V +DSL+ C 
Sbjct: 420  AEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECA 479

Query: 2989 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK-----------GKKRRGR 3037
             T S+     DS QP+ +     EE  V  +L V       +           G      
Sbjct: 480  ITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSAT 539

Query: 3038 RSKKERRRGRKEGEEDQN---PPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCL----- 3089
                    G    E+ +        +L  +L ++K  +  ++  ++C+ T   C      
Sbjct: 540  NVSMVVSAGPLSSEKAEMNILEMNEKLRPQLAEKK--QQFRNLKEKCFVTQLACFLANQQ 597

Query: 3090 -----ELCDSC--QPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 3142
                 E C        R+     E++        +E+ +Y+ +   Q+    +L  +L +
Sbjct: 598  NKYKYEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLRE 657

Query: 3143 EKGPEVLQDSLDRCYSTPSG---------CLELCDSCQPYRSAFYILEQQRVGLAVDMDE 3193
             +      +   +   TP             +L + C+  +  F  L  +      D DE
Sbjct: 658  GRDASRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDN---DHDE 714

Query: 3194 IEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY 3253
              + +  E+ Q  S P   RE+   +E EV +DSL+ C  T S      D  QP+     
Sbjct: 715  DVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKI 771

Query: 3254 SLEEQYLGLAL--------------DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 3299
            + EE  +   L               +   + D EEEE++GP  P   R L E  E EV 
Sbjct: 772  TFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSP---RNLQESEEEEVP 828

Query: 3300 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 3359
            Q+S D  YST S   E   S Q Y  +F++LEE+ V  ++D+G            G R  
Sbjct: 829  QESWDEGYSTLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDIG------------GHRWD 876

Query: 3360 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRS 3419
            + ++       EDQ    PRLSRELLDEKGPEVLQDSLDRCYSTPSG LEL DSCQPYRS
Sbjct: 877  QVKK-------EDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRS 929

Query: 3420 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 3479
            AFY+LEQQ VG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP
Sbjct: 930  AFYILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 989

Query: 3480 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGE 3539
            SGYLELPDLGQPY SAVYSLEEQYLGLALDVD+I+K                    +E E
Sbjct: 990  SGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKD-------------------QEEE 1030

Query: 3540 EDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHIS 3599
            EDQ PPCPRL+  L+E  E EVLQDSLDRCYSTPS   E PDS   Y S FY+ EE+H+ 
Sbjct: 1031 EDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVG 1090

Query: 3600 FALYV 3604
            F+L V
Sbjct: 1091 FSLDV 1095


>gi|7657017 hypothetical protein LOC25832 [Homo sapiens]
          Length = 921

 Score = 1539 bits (3984), Expect = 0.0
 Identities = 775/917 (84%), Positives = 812/917 (88%), Gaps = 38/917 (4%)

Query: 341  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQA 400
            MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQL+EKLREGRDASRSLNEHLQA
Sbjct: 1    MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60

Query: 401  LLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 460
            LLTP EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR
Sbjct: 61   LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120

Query: 461  EMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 520
            EMQKAEEKEVPEDSLEECAIT SNSHG YDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 121  EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180

Query: 521  EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQS 580
            EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY+S
Sbjct: 181  EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKS 240

Query: 581  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCY 640
            YSSTFHSLEEQQVCMAVDIGRHRWDQVKKED EATGPRLSRELLDEKGPEV QDS DRCY
Sbjct: 241  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300

Query: 641  STPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 700
            STPSGCLELTDSCQPYRSAFY+LEQQRVGLA++MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 301  STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360

Query: 701  EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 760
            EKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 361  EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420

Query: 761  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 820
            DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 421  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480

Query: 821  SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 880
            SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL
Sbjct: 481  SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540

Query: 881  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSR 940
            DRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVG AVDMDEIEKYQEVEEDQDPSCPRLS 
Sbjct: 541  DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSG 600

Query: 941  ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQ 1000
            ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K Q
Sbjct: 601  ELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQ 660

Query: 1001 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 1060
            E EEDQ P CPRLSRELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+
Sbjct: 661  EVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 720

Query: 1061 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVL 1120
            ++G +LDV  I+K                    +E EEDQ PPCPRLSRELL+   PEVL
Sbjct: 721  YLGLALDVDRIKKD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVL 761

Query: 1121 QDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEK------------- 1167
            QDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VGF++D+ EIEK             
Sbjct: 762  QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 821

Query: 1168 ------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS 1221
                   +E EEDQ+P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S
Sbjct: 822  KERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRS 881

Query: 1222 AVYSLEEQYLGLALDVD 1238
              YS EE+++  AL VD
Sbjct: 882  VFYSFEEEHISFALYVD 898



 Score = 1250 bits (3235), Expect = 0.0
 Identities = 645/824 (78%), Positives = 683/824 (82%), Gaps = 39/824 (4%)

Query: 2627 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2686
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156

Query: 2687 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2732
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213

Query: 2733 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2792
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260

Query: 2793 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2852
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314

Query: 2853 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2912
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374

Query: 2913 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2972
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434

Query: 2973 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 3032
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494

Query: 3033 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELC 3092
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP+VLQDSLDRCYSTPSGCLEL 
Sbjct: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554

Query: 3093 DSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDS 3152
            DSCQPYRSAFY+LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEK PEVLQ+S
Sbjct: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614

Query: 3153 LDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 3212
            LDRCYSTPSGCLEL DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS
Sbjct: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674

Query: 3213 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 3272
            RELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD
Sbjct: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734

Query: 3273 QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 3332
            QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE
Sbjct: 735  QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE 794

Query: 3333 KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEV 3392
            KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL+  L++ + PEV
Sbjct: 795  KHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEV 854

Query: 3393 LQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436
            LQDSLD CYSTPS   EL DS Q YRS FY  E++H+  A+ +D
Sbjct: 855  LQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 898



 Score = 1062 bits (2746), Expect = 0.0
 Identities = 567/843 (67%), Positives = 624/843 (74%), Gaps = 77/843 (9%)

Query: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156

Query: 2199 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2244
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213

Query: 2245 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2304
             EV Q+S D  YST S   E   S + Y S+F++LEE  V  ++D+G             
Sbjct: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260

Query: 2305 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2364
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314

Query: 2365 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2424
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374

Query: 2425 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2484
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434

Query: 2485 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2544
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494

Query: 2545 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2604
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554

Query: 2605 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2664
            DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614

Query: 2665 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS 2724
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLS
Sbjct: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674

Query: 2725 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2784
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734

Query: 2785 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 2844
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775

Query: 2845 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVEEDQ 2885
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835

Query: 2886 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2945
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895

Query: 2946 DVD 2948
             VD
Sbjct: 896  YVD 898



 Score = 1061 bits (2745), Expect = 0.0
 Identities = 567/843 (67%), Positives = 623/843 (73%), Gaps = 77/843 (9%)

Query: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156

Query: 1711 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213

Query: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816
             EV Q+S D  YST S   E   S + Y S+F++LEE  V  ++D+G             
Sbjct: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260

Query: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314

Query: 1877 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1936
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374

Query: 1937 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1996
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434

Query: 1997 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2056
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494

Query: 2057 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2116
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554

Query: 2117 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2176
            DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614

Query: 2177 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS 2236
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLS
Sbjct: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674

Query: 2237 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKK 2296
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV  I+K 
Sbjct: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734

Query: 2297 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 2356
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775

Query: 2357 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVEEDQ 2397
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835

Query: 2398 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2457
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895

Query: 2458 DVD 2460
             VD
Sbjct: 896  YVD 898



 Score = 1061 bits (2745), Expect = 0.0
 Identities = 567/843 (67%), Positives = 623/843 (73%), Gaps = 77/843 (9%)

Query: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156

Query: 1955 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213

Query: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060
             EV Q+S D  YST S   E   S + Y S+F++LEE  V  ++D+G             
Sbjct: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260

Query: 2061 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2120
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314

Query: 2121 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2180
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374

Query: 2181 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2240
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434

Query: 2241 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2300
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494

Query: 2301 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2360
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554

Query: 2361 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2420
            DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614

Query: 2421 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS 2480
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLS
Sbjct: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674

Query: 2481 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKK 2540
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV  I+K 
Sbjct: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734

Query: 2541 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 2600
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775

Query: 2601 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVEEDQ 2641
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835

Query: 2642 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2701
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895

Query: 2702 DVD 2704
             VD
Sbjct: 896  YVD 898



 Score = 1059 bits (2739), Expect = 0.0
 Identities = 565/843 (67%), Positives = 625/843 (74%), Gaps = 77/843 (9%)

Query: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156

Query: 733  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213

Query: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260

Query: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314

Query: 899  PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
            PYRSAFYVLEQQRVG AV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374

Query: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434

Query: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494

Query: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554

Query: 1139 DSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1198
            DSCQPYRSAFY+LEQQRVG AVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614

Query: 1199 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLS 1258
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K +E EEDQDP CPRLS
Sbjct: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674

Query: 1259 RELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 1318
            RELL+   PEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734

Query: 1319 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 1378
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775

Query: 1379 LELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEK-------------------YQEVEEDQ 1419
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835

Query: 1420 DPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 1479
            +P CPRL+  L++ +EPEVLQDSL+ CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895

Query: 1480 DVD 1482
             VD
Sbjct: 896  YVD 898



 Score = 1058 bits (2735), Expect = 0.0
 Identities = 566/843 (67%), Positives = 624/843 (74%), Gaps = 75/843 (8%)

Query: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYS 1464
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL  C  T S      D  QP+ 
Sbjct: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156

Query: 1465 SAVYSLEEQYLGLAL----------DVDRI--KKDQEEEEDEDQDPPCPRLSRELLEVVE 1512
                + EE  +   L          D   I  + + ++EE+E++ P  PR    L E  E
Sbjct: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213

Query: 1513 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1572
             EV Q+S D  YST S   E   S + Y S+F++LEE  V  ++D+G             
Sbjct: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260

Query: 1573 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1632
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314

Query: 1633 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1692
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374

Query: 1693 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1752
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434

Query: 1753 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 1812
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494

Query: 1813 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1872
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554

Query: 1873 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1932
            DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614

Query: 1933 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS 1992
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLS
Sbjct: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674

Query: 1993 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKK 2052
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV  I+K 
Sbjct: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734

Query: 2053 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 2112
                               +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS C
Sbjct: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775

Query: 2113 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVEEDQ 2153
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835

Query: 2154 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2213
            +P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  AL
Sbjct: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895

Query: 2214 DVD 2216
             VD
Sbjct: 896  YVD 898



 Score = 1055 bits (2728), Expect = 0.0
 Identities = 565/845 (66%), Positives = 625/845 (73%), Gaps = 79/845 (9%)

Query: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156

Query: 977  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1022
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213

Query: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082
             EV Q+S D  YST S   E   S + Y S+F++LEE+ V  ++D+G             
Sbjct: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260

Query: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314

Query: 1143 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202
            PYRSAFYVLEQQRVG AV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374

Query: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELL 1262
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD+EEEEDQ PPCPRLSRELL
Sbjct: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434

Query: 1263 EVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322
            EVV PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494

Query: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1382
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554

Query: 1383 DSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 1442
            DSCQPYRSAFY+LEQQRVG+AVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614

Query: 1443 LNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPR 1502
            L+RCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE E  EDQDP CPR
Sbjct: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVE--EDQDPSCPR 672

Query: 1503 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIE 1562
            LSRELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE ++G +LDV  I+
Sbjct: 673  LSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIK 732

Query: 1563 KKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPS 1622
            K                    +E EEDQ PPCPRLSRELL+   PEVLQDSLDRCYSTPS
Sbjct: 733  KD-------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 773

Query: 1623 GCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEK-------------------YQEVEE 1663
             CLE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EE
Sbjct: 774  SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 833

Query: 1664 DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGL 1723
            DQ+P CPRL+  L++ +EPEVLQDSLD CYSTPS Y ELPD  Q Y S  YS EE+++  
Sbjct: 834  DQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISF 893

Query: 1724 ALDVD 1728
            AL VD
Sbjct: 894  ALYVD 898



 Score = 1050 bits (2715), Expect = 0.0
 Identities = 562/843 (66%), Positives = 622/843 (73%), Gaps = 77/843 (9%)

Query: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 100  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 156

Query: 2443 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2488
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 157  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 213

Query: 2489 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2548
             EV Q+S D  YST S   E   S + Y S+F++LEE  V  ++D+G             
Sbjct: 214  EEVPQESWDEGYSTLSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIG------------- 260

Query: 2549 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2608
                  R R  +  +ED     PRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 261  ------RHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 314

Query: 2609 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2668
            PYRSAFYVLEQQ VGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RC
Sbjct: 315  PYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRC 374

Query: 2669 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2728
            YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 375  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 434

Query: 2729 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2788
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 435  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 494

Query: 2789 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2848
            KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT
Sbjct: 495  KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 554

Query: 2849 DSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDS 2908
            DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS ELLDEKEPEVLQ+S
Sbjct: 555  DSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQES 614

Query: 2909 LDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLS 2968
            LDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D I+K QE EEDQ P CPRLS
Sbjct: 615  LDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLS 674

Query: 2969 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 3028
            RELL+  EPEVLQDSL RCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV  I+K 
Sbjct: 675  RELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD 734

Query: 3029 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGC 3088
                               +E EEDQ PPCPRLSRELL+   P+VLQDSLDRCYSTPS C
Sbjct: 735  -------------------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSC 775

Query: 3089 LELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEK-------------------YQEVEEDQ 3129
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 776  LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 835

Query: 3130 DPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAV 3189
            +P CPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E++ +  A+
Sbjct: 836  NPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFAL 895

Query: 3190 DMD 3192
             +D
Sbjct: 896  YVD 898



 Score =  962 bits (2488), Expect = 0.0
 Identities = 523/843 (62%), Positives = 602/843 (71%), Gaps = 74/843 (8%)

Query: 2819 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVD------- 2871
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+  V   +        
Sbjct: 120  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 179

Query: 2872 -------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPD 2924
                   + E E   E EE++ P  PR    L + +E EV Q+S D  YST S   E+  
Sbjct: 180  WEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLA 236

Query: 2925 LGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 2984
              + YSS  +SLEEQ + +A+D+ R + DQ ++ED     PRLSRELL+   PEVLQDSL
Sbjct: 237  SYKSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSL 296

Query: 2985 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 3044
            DRCYSTPS CLE  DSCQPY S+FY LE++ VG ++++ EIEK                 
Sbjct: 297  DRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY---------------- 340

Query: 3045 RGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYV 3104
               +E EEDQ+P CPRLSRELLDEK P+VLQDSL RCYSTPSG LEL D  QPY SA Y 
Sbjct: 341  ---QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYS 397

Query: 3105 LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCL 3164
            LE+Q +GLA+D+D I+K QE EEDQ P CPRLSRELL+   PEVLQDSLDRCYSTPS CL
Sbjct: 398  LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 457

Query: 3165 ELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKY-------------------QEVEEDQD 3205
            E  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ+
Sbjct: 458  EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQN 517

Query: 3206 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 3265
            P CPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D
Sbjct: 518  PPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 577

Query: 3266 VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGS 3325
            +D I+K QE EEDQ P CPRLS ELL+  EPEVLQ+SLDRCYSTPS CLE  DSCQPY S
Sbjct: 578  MDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRS 637

Query: 3326 SFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELL 3385
            +FY LE++ VG ++D+ EIEK                    +E EEDQ+P CPRLSRELL
Sbjct: 638  AFYILEQQRVGLAVDMDEIEKY-------------------QEVEEDQDPSCPRLSRELL 678

Query: 3386 DEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVE 3445
            DEK PEVLQDSL RCYSTPSG LEL D  QPY SA Y LE+Q++GLA+D+D I+K QE E
Sbjct: 679  DEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEE 738

Query: 3446 EDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLG 3505
            EDQ P CPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G
Sbjct: 739  EDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 798

Query: 3506 LALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDS 3565
             +LDV +IEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLN +LMEVEE EVLQDS
Sbjct: 799  FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDS 858

Query: 3566 LDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVI 3625
            LD CYSTPSMYFELPDSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLHLVFQMGVI
Sbjct: 859  LDICYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVI 918

Query: 3626 FPQ 3628
            FPQ
Sbjct: 919  FPQ 921



 Score =  906 bits (2342), Expect = 0.0
 Identities = 528/906 (58%), Positives = 611/906 (67%), Gaps = 64/906 (7%)

Query: 70  MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQA 129
           MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDASRSL EHLQA
Sbjct: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60

Query: 130 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR 189
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AEKV +SSAPR
Sbjct: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120

Query: 190 EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHD 249
           E+QKAEE +VPEDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL+    SSH 
Sbjct: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHV 178

Query: 250 ECQDALNILP----------VPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQL 299
           E +DA++I+P            GP S            P  S     + L I  ++    
Sbjct: 179 EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASY 238

Query: 300 AEKKQQFRNLKEK--CFLTQLSGFLANQQKKYKYEECKDLIKFMLRNER--QFKEEKL-- 353
                 F +L+E+  C    +     +Q KK  +E     +   L +E+  +  ++ L  
Sbjct: 239 KSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDR 298

Query: 354 -----AEQLKQAEELRQYKVLVHAQERELTQLK------EKLRE-GRDASRSLNEHLQAL 401
                +  L+  +  + Y+   +  E++   L       EK +E   D   S     + L
Sbjct: 299 CYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSREL 358

Query: 402 LTPYEPDKSQGQ---------------DLQEQLAEGCRL--AQHLVQKLSPENDNDDDED 444
           L   EP+  Q                 DL +  +        Q+L   L  +    D E+
Sbjct: 359 LDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEE 418

Query: 445 VQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKIT 501
                 E+ Q    P   RE+ +  E EV +DSL+ C  T S+     DS QP+  +   
Sbjct: 419 ------EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYA 472

Query: 502 FEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-----DEEEEEKGPVSPRNLQESEEE-- 554
            EE  V  +L       + +        ++ +      E EE++ P  PR  +E  +E  
Sbjct: 473 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKG 532

Query: 555 -EVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 613
            EV Q+S D  YST S   E+  S Q Y S F+ LE+Q+V +AVD+      Q  +EDQ+
Sbjct: 533 PEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQD 592

Query: 614 ATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAID 673
            + PRLS ELLDEK PEV Q+S DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLA+D
Sbjct: 593 PSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVD 652

Query: 674 MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSS 733
           MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL RCYSTPSGYLELPDLGQPYSS
Sbjct: 653 MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSS 712

Query: 734 AVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 793
           AVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP
Sbjct: 713 AVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 772

Query: 794 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 853
           SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE
Sbjct: 773 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 832

Query: 854 EDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVG 913
           EDQNPPCPRL+  L++ + PEVLQDSLD CYSTPS   EL DS Q YRS FY  E++ + 
Sbjct: 833 EDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHIS 892

Query: 914 FAVDMD 919
           FA+ +D
Sbjct: 893 FALYVD 898



 Score =  857 bits (2215), Expect = 0.0
 Identities = 473/748 (63%), Positives = 539/748 (72%), Gaps = 54/748 (7%)

Query: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 21   EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 71

Query: 2933 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2977
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 72   GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEK 128

Query: 2978 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3037
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 129  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 188

Query: 3038 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQP 3097
             ++ +      E EE++ P  PR  +E  +E+ P   Q+S D  YST S   E+  S + 
Sbjct: 189  ENESD-----DEEEEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYKS 240

Query: 3098 YRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCY 3157
            Y S F+ LE+Q+V +AVD+      Q  +ED + + PRLSRELLDEKGPEVLQDSLDRCY
Sbjct: 241  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDHEATGPRLSRELLDEKGPEVLQDSLDRCY 300

Query: 3158 STPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 3217
            STPSGCLEL DSCQPYRSAFY+LEQQRVGLAV+MDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 301  STPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKYQEVEEDQDPSCPRLSRELLD 360

Query: 3218 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 3277
            EKEPEVLQDSL RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 361  EKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 420

Query: 3278 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 3337
            DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 421  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 480

Query: 3338 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 3397
            SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL
Sbjct: 481  SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 540

Query: 3398 DRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSR 3457
            DRCYSTPSGCLEL DSCQPYRSAFY+LEQQ VGLAVDMDEIEKYQEVEEDQDPSCPRLS 
Sbjct: 541  DRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSG 600

Query: 3458 ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKG 3517
            ELLDEKEPEVLQ+SLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D+IEK  
Sbjct: 601  ELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEK-- 658

Query: 3518 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYF 3577
                              +E EEDQ+P CPRL+  L++ +E EVLQDSL RCYSTPS Y 
Sbjct: 659  -----------------YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYL 701

Query: 3578 ELPDSFQHYRSVFYSFEEQHISFALYVD 3605
            ELPD  Q Y S  YS EEQ++  AL VD
Sbjct: 702  ELPDLGQPYSSAVYSLEEQYLGLALDVD 729


>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
           sapiens]
          Length = 790

 Score = 1330 bits (3441), Expect = 0.0
 Identities = 679/765 (88%), Positives = 705/765 (92%), Gaps = 6/765 (0%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLA 149
           EE++QYKVLVHSQERELTQLREKLREGRDASRSL EHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15  EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 150 EGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAI 209
           EGCRLAQHLVQKLSPENDEDEDEDVQVEE EKVLESSAPREVQKAEESKVPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 210 TCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATN 269
           TCSNSHGPCDS QPHKNIKITFEED+VNS+LVVDRESSHD CQDALNILPVPGPTSSATN
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATN 194

Query: 270 VSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKY 329
           VSMVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFR+LKEKCF+TQ++ FLA QQ KY
Sbjct: 195 VSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKY 254

Query: 330 KYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRD 389
           KYEECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRD
Sbjct: 255 KYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRD 314

Query: 390 ASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV 449
           ASRSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV
Sbjct: 315 ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV 374

Query: 450 AEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDS 509
           AEKVQKSS+PREMQKAEEKEVPEDSLEECAIT SNSHG YDSNQPHRKTKITFEEDKVDS
Sbjct: 375 AEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDS 434

Query: 510 TLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 569
           TLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS
Sbjct: 435 TLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 494

Query: 570 IPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGP 629
           IPPE LASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK P
Sbjct: 495 IPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEP 554

Query: 630 EVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDP 689
           EV QDS DRCYSTPS  L LTDSCQPYRSAFY+LEQQR+GLA+DMDEIEKYQEVEEDQDP
Sbjct: 555 EVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDP 614

Query: 690 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDV 749
           SCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDV
Sbjct: 615 SCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDV 674

Query: 750 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 809
           DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD     P   L       P    
Sbjct: 675 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLPV-VLNSLTPASPTEVP 733

Query: 810 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 854
           F    +  + F L   +++++G     RGR+  +E +R ++EGEE
Sbjct: 734 FMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKEEGEE 773



 Score =  642 bits (1657), Expect = 0.0
 Identities = 406/800 (50%), Positives = 483/800 (60%), Gaps = 103/800 (12%)

Query: 361  EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420
            EE++QYKVLVH+QERELTQL+EKLREGRDASRSLNEHLQALLTP EPDKSQGQDLQEQLA
Sbjct: 15   EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            EGCRLAQHLVQKLSPEND D+DEDVQVE  EKV +SSAPRE+QKAEE +VPEDSLEECAI
Sbjct: 75   EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 481  TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 538
            T SNSHG  DS QPH+  KITFEEDKV+S+L+    SSH   +DA++I+P          
Sbjct: 135  TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPV--------- 185

Query: 539  EKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEE-----QQV 593
              GP S            P  S     + L I  ++          F SL+E     Q  
Sbjct: 186  -PGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVA 244

Query: 594  C-MAVDIGRHRWDQVK-------------KEDQEATGPRLSRELLDEKG----------- 628
            C +A    ++++++ K             KE++ A   + + EL   K            
Sbjct: 245  CFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ 304

Query: 629  -PEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRV-GLAI-------------- 672
              E  ++ +D   S       L    +P +S    L++Q   G  +              
Sbjct: 305  LREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN 364

Query: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 365  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 421

Query: 733  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 422  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 478

Query: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838
             EV Q+S D  YST S   E+  S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 479  EEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG------------- 525

Query: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQ
Sbjct: 526  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQ 579

Query: 899  PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
            PYRSAFYVLEQQR+G AVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRC
Sbjct: 580  PYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRC 639

Query: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018
            YSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 640  YSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 699

Query: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078
            EVVEPEVLQDSLD     P   L       P    F    +  + F L   +++++G   
Sbjct: 700  EVVEPEVLQDSLDVIQLLPV-VLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG--- 755

Query: 1079 KRRGRRSKKERRRGRKEGEE 1098
              RGR+  +E +R ++EGEE
Sbjct: 756  --RGRKEGEEDQRRKEEGEE 773



 Score =  455 bits (1170), Expect = e-127
 Identities = 294/591 (49%), Positives = 368/591 (62%), Gaps = 64/591 (10%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINE L PQLAEKKQQFR+LKEKCF+TQ+A FLA +Q KYKY
Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKY 256

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 257 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 316

Query: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
           RSL EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AE
Sbjct: 317 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 376

Query: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +SS+PRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 377 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 436

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           +    SSH E +DA++I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 437 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQES 485

Query: 301 -EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQ 359
            ++     ++  +    +L+ + +     +  EE +  +   +   R    +++ ++ ++
Sbjct: 486 WDEGYSTLSIPPE----RLASYQSYSSTFHSLEEQQVCMAVDIGRHRW---DQVKKEDQE 538

Query: 360 AEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQL 419
           A   R  + L+  +E E+      L++  D   S       L    +P +S    L++Q 
Sbjct: 539 ATGPRLSRELLDEKEPEV------LQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQ- 591

Query: 420 AEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLE 476
               R+   +          D DE  + +  E+ Q  S P   RE+   +E EV +DSL+
Sbjct: 592 ----RIGLAV----------DMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLD 637

Query: 477 ECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEE 536
            C  T S      D  QP+R    + EE  +   L               +   + D EE
Sbjct: 638 RCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLAL--------------DVDRIKKDQEE 683

Query: 537 EEEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSST 584
           EE++GP  P   R L E  E EV Q+S D     + + P +L S    S T
Sbjct: 684 EEDQGPPCPRLSRELLEVVEPEVLQDSLD----VIQLLPVVLNSLTPASPT 730



 Score =  415 bits (1067), Expect = e-115
 Identities = 310/736 (42%), Positives = 384/736 (52%), Gaps = 104/736 (14%)

Query: 1398 QRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELP 1457
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL  C  T S      
Sbjct: 85   QKLSPENDEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPC 143

Query: 1458 DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDP----PCPR----------- 1502
            D  QP+ +   + EE  +  +L VDR     E   D  QD     P P            
Sbjct: 144  DSIQPHKNIKITFEEDKVNSSLVVDR-----ESSHDGCQDALNILPVPGPTSSATNVSMV 198

Query: 1503 -----LSRELLEVVEPEV-------LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEN 1550
                 LS E  E+   E+       L +   +  S    C     +C      F A ++N
Sbjct: 199  VSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVAC------FLAKQQN 252

Query: 1551 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEV 1609
               +     E +   K   R  R+ K+E+   + K+ EE +       S+E    +  E 
Sbjct: 253  KYKYE----ECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREK 308

Query: 1610 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ---------HVGLAV------DMDE 1654
            L++  D   S       L    +P +S    L++Q         H+   +      D DE
Sbjct: 309  LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDE 368

Query: 1655 IEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY 1714
              + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+     
Sbjct: 369  DVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKI 425

Query: 1715 SLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 1760
            + EE  +   L               +   + D EEEE++GP  PR    L E  E EV 
Sbjct: 426  TFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVP 482

Query: 1761 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 1820
            Q+S D  YST S   E+  S Q Y S+F++LEE  V  ++D+G                 
Sbjct: 483  QESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG----------------- 525

Query: 1821 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 1880
              R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRS
Sbjct: 526  --RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRS 583

Query: 1881 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 1940
            AFYVLEQQ +GLAVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTP
Sbjct: 584  AFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTP 643

Query: 1941 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000
            SGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE
Sbjct: 644  SGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 703

Query: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060
            PEVLQDSLD     P   L       P    F    +N + F L   +++++G     RG
Sbjct: 704  PEVLQDSLDVIQLLPV-VLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RG 757

Query: 2061 RRSKKERRRGRKEGEE 2076
            R+  +E +R ++EGEE
Sbjct: 758  RKEGEEDQRRKEEGEE 773



 Score =  412 bits (1060), Expect = e-114
 Identities = 303/724 (41%), Positives = 379/724 (52%), Gaps = 96/724 (13%)

Query: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 92   DEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHK 150

Query: 1711 SAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLS 1748
            +   + EE  +  +L VDR       ++                       GP    +  
Sbjct: 151  NIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 210

Query: 1749 RELLEVVEP--EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIE 1806
              +LE+ E     L +   +  S    C     +C      F A ++N   +     E +
Sbjct: 211  MNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVAC------FLAKQQNKYKYE----ECK 260

Query: 1807 KKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTP 1865
               K   R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S  
Sbjct: 261  DLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLN 320

Query: 1866 SGCLELTDSCQPYRSAFYVLEQQ---------HVGLAV------DMDEIEKYQEVEEDQD 1910
                 L    +P +S    L++Q         H+   +      D DE  + +  E+ Q 
Sbjct: 321  EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 380

Query: 1911 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 1970
             S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L 
Sbjct: 381  SSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI 437

Query: 1971 --------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2016
                          +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S
Sbjct: 438  GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLS 494

Query: 2017 SCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 2076
               E+  S Q Y S+F++LEE  V  ++D+G                   R R  +  +E
Sbjct: 495  IPPERLASYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKE 535

Query: 2077 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGL 2136
            DQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQ +GL
Sbjct: 536  DQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGL 595

Query: 2137 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 2196
            AVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLELPDLGQP
Sbjct: 596  AVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 655

Query: 2197 YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 2256
            Y SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD   
Sbjct: 656  YRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQ 715

Query: 2257 STPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 2316
              P   L       P    F    +N + F L   +++++G     RGR+  +E +R ++
Sbjct: 716  LLPV-VLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKE 769

Query: 2317 EGEE 2320
            EGEE
Sbjct: 770  EGEE 773



 Score =  412 bits (1060), Expect = e-114
 Identities = 303/724 (41%), Positives = 379/724 (52%), Gaps = 96/724 (13%)

Query: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 92   DEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHK 150

Query: 1955 SAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLS 1992
            +   + EE  +  +L VDR       ++                       GP    +  
Sbjct: 151  NIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 210

Query: 1993 RELLEVVEP--EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIE 2050
              +LE+ E     L +   +  S    C     +C      F A ++N   +     E +
Sbjct: 211  MNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVAC------FLAKQQNKYKYE----ECK 260

Query: 2051 KKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTP 2109
               K   R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S  
Sbjct: 261  DLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLN 320

Query: 2110 SGCLELTDSCQPYRSAFYVLEQQ---------HVGLAV------DMDEIEKYQEVEEDQD 2154
                 L    +P +S    L++Q         H+   +      D DE  + +  E+ Q 
Sbjct: 321  EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 380

Query: 2155 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 2214
             S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L 
Sbjct: 381  SSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI 437

Query: 2215 --------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2260
                          +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S
Sbjct: 438  GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLS 494

Query: 2261 SCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 2320
               E+  S Q Y S+F++LEE  V  ++D+G                   R R  +  +E
Sbjct: 495  IPPERLASYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKE 535

Query: 2321 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGL 2380
            DQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQ +GL
Sbjct: 536  DQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGL 595

Query: 2381 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 2440
            AVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLELPDLGQP
Sbjct: 596  AVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 655

Query: 2441 YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 2500
            Y SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD   
Sbjct: 656  YRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQ 715

Query: 2501 STPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 2560
              P   L       P    F    +N + F L   +++++G     RGR+  +E +R ++
Sbjct: 716  LLPV-VLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKE 769

Query: 2561 EGEE 2564
            EGEE
Sbjct: 770  EGEE 773



 Score =  411 bits (1056), Expect = e-114
 Identities = 308/745 (41%), Positives = 383/745 (51%), Gaps = 111/745 (14%)

Query: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 92   DEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHK 150

Query: 2443 SAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLS 2480
            +   + EE  +  +L VDR       ++                       GP    +  
Sbjct: 151  NIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 210

Query: 2481 RELLEVVEP--EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIE 2538
              +LE+ E     L +   +  S    C     +C      F A ++N   +     E +
Sbjct: 211  MNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVAC------FLAKQQNKYKYE----ECK 260

Query: 2539 KKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTP 2597
               K   R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S  
Sbjct: 261  DLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLN 320

Query: 2598 SGCLELTDSCQPYRSAFYVLEQQ---------HVGLAV------DMDEIEKYQEVEEDQD 2642
                 L    +P +S    L++Q         H+   +      D DE  + +  E+ Q 
Sbjct: 321  EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 380

Query: 2643 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 2702
             S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L 
Sbjct: 381  SSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI 437

Query: 2703 --------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2748
                          +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S
Sbjct: 438  GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLS 494

Query: 2749 SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 2808
               E+  S Q Y S+F++LEE+ V  ++D+G                   R R  +  +E
Sbjct: 495  IPPERLASYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKE 535

Query: 2809 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGL 2868
            DQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQ +GL
Sbjct: 536  DQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGL 595

Query: 2869 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 2928
            AVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLELPDLGQP
Sbjct: 596  AVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 655

Query: 2929 YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 2988
            Y SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD   
Sbjct: 656  YRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQ 715

Query: 2989 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 3048
              P   L       P    F    +  + F L   +++++G               RGRK
Sbjct: 716  LLP-VVLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG---------------RGRK 759

Query: 3049 EGEEDQNPPCPRLSRELLDEKGPKV 3073
            EGEEDQ     R   E  ++KG K+
Sbjct: 760  EGEEDQ-----RRKEEGEEKKGKKI 779



 Score =  405 bits (1040), Expect = e-112
 Identities = 316/835 (37%), Positives = 413/835 (49%), Gaps = 124/835 (14%)

Query: 566  STLSIPPEMLASYQSYSSTFHSLEEQ--QVCMAVDIGRHRWDQVKKEDQEATGPRLSREL 623
            ST  +P +     Q Y    HS E +  Q+   +  GR     + +  Q    P      
Sbjct: 5    STGRLPGQPTEEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP------ 58

Query: 624  LDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEV 683
             DE      QD Q+          +L + C   R A +++  Q++    D DE E  Q V
Sbjct: 59   -DEPDKSQGQDLQE----------QLAEGC---RLAQHLV--QKLSPENDEDEDEDVQ-V 101

Query: 684  EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 743
            EED+        RE+   +E +V +DSL+ C  T S      D  QP+ +   + EE  +
Sbjct: 102  EEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKV 161

Query: 744  GLALDVDRIKKDQEEEE---------------------DQGP-PCPRLSRELLEVVE--- 778
              +L VDR       ++                       GP    +    +LE+ E   
Sbjct: 162  NSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLC 221

Query: 779  PEVLQDSL------DRCYSTPSSCL-------EQPDSCQPYGSSFYALE----EKHVGFS 821
            P++ +         ++C+ T  +C         + + C+    S    E    E+ +   
Sbjct: 222  PQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQ 281

Query: 822  LDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLD 881
            L   E  ++ K       R   + R   +EG +        L   L  ++  +     L 
Sbjct: 282  LKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQ 341

Query: 882  RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRE 941
                      +L + C   R A +++++       D DE  + +  E+ Q  S PR   E
Sbjct: 342  E---------QLAEGC---RLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---E 386

Query: 942  LLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD--------- 992
            +   +E EV +DSL+ C  T S      D  QP+     + EE  +   L          
Sbjct: 387  MQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWE 446

Query: 993  -----VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 1047
                 +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E+  S 
Sbjct: 447  DAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPERLASY 503

Query: 1048 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 1107
            Q Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    PRL
Sbjct: 504  QSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGPRL 544

Query: 1108 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEK 1167
            SRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQR+G AVDMDEIEK
Sbjct: 545  SRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEK 604

Query: 1168 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLE 1227
            YQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLELPDLGQPY SAVYSLE
Sbjct: 605  YQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLE 664

Query: 1228 EQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQ 1287
            EQYLGLALDVDRIKKD+EEEEDQ PPCPRLSRELLEVV PEVLQDSLD     P   L  
Sbjct: 665  EQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLPV-VLNS 723

Query: 1288 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 1342
                 P    F    +  + F L   +++++G     RGR+  +E +R ++EGEE
Sbjct: 724  LTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKEEGEE 773



 Score =  403 bits (1036), Expect = e-111
 Identities = 306/800 (38%), Positives = 409/800 (51%), Gaps = 98/800 (12%)

Query: 2629 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2688
            +EI++Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 15   EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 65

Query: 2689 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPR--------LSRELLEVVEPEVL 2736
               L+EQ   G  L    V ++  + +E+ED+                RE+ +  E +V 
Sbjct: 66   GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVP 125

Query: 2737 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVG-EIEKKG---------- 2785
            +DSL+ C  T S+     DS QP+ +     EE  V  SL V  E    G          
Sbjct: 126  EDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPV 185

Query: 2786 KGKKRRGRRSKKERRRGRKEGE-------EDQNPPCPRLSRELLDEKGPEVLQDSLDRCY 2838
             G              G    E       E     CP+L+ +       +  +   ++C+
Sbjct: 186  PGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEK------KQQFRSLKEKCF 239

Query: 2839 STPSGCLELT-------DSCQPYRSAFYVLEQQ--HVGLAVDM---DEIEKYQEVEEDQD 2886
             T   C           + C+    +    E+Q     LA  +   +E+ +Y+ +   Q+
Sbjct: 240  VTQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQE 299

Query: 2887 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLAL 2945
                +L  +L + ++     +   +   TP          +P  S    L+EQ   G  L
Sbjct: 300  RELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQGQDLQEQLAEGCRL 350

Query: 2946 DVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 2991
                ++K     D +++ED         Q    PR   E+ +  E EV +DSL+ C  T 
Sbjct: 351  AQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITC 407

Query: 2992 SSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGE 3051
            S+     DS QP+  +    EE  V  +L       + +        ++ +      E E
Sbjct: 408  SNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-----DEEE 462

Query: 3052 EDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVG 3111
            E++ P  PR  +E  +E+ P   Q+S D  YST S   E   S Q Y S F+ LE+Q+V 
Sbjct: 463  EEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVC 519

Query: 3112 LAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQ 3171
            +AVD+      Q  +EDQ+ + PRLSRELLDEK PEVLQDSLDRCYSTPS  L L DSCQ
Sbjct: 520  MAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQ 579

Query: 3172 PYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3231
            PYRSAFY+LEQQR+GLAVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRC
Sbjct: 580  PYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRC 639

Query: 3232 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 3291
            YSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 640  YSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 699

Query: 3292 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 3351
            EVVEPEVLQDSLD     P   L       P    F    +  + F L   +++++G   
Sbjct: 700  EVVEPEVLQDSLDVIQLLPV-VLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG--- 755

Query: 3352 KRRGRRSKKERRRGRKEGEE 3371
              RGR+  +E +R ++EGEE
Sbjct: 756  --RGRKEGEEDQRRKEEGEE 773



 Score =  398 bits (1023), Expect = e-110
 Identities = 293/728 (40%), Positives = 377/728 (51%), Gaps = 102/728 (14%)

Query: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 92   DEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHK 150

Query: 977  SAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLS 1014
            +   + EE  +  +L VDR       ++                       GP    +  
Sbjct: 151  NIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 210

Query: 1015 RELLEVVE---PEVLQDSL------DRCYSTPSSCL-------EQPDSCQPYGSSFYALE 1058
              +LE+ E   P++ +         ++C+ T  +C         + + C+    S    E
Sbjct: 211  MNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNE 270

Query: 1059 ----EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 1114
                E+ +   L   E  ++ K       R   + R   +EG +        L   L  +
Sbjct: 271  RQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD 330

Query: 1115 KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEED 1174
            +  +     L           +L + C   R A +++++       D DE  + +  E+ 
Sbjct: 331  EPDKSQGQDLQE---------QLAEGC---RLAQHLVQKLSPENDNDDDEDVQVEVAEKV 378

Query: 1175 QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 1234
            Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE  +   
Sbjct: 379  QKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDST 435

Query: 1235 LD--------------VDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYST 1280
            L               +   + D+EEEE++ P  PR    L E    EV Q+S D  YST
Sbjct: 436  LIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYST 492

Query: 1281 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 1340
             S   E+  S Q Y S+F++LEE+ V  ++D+G                   R R  +  
Sbjct: 493  LSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVK 533

Query: 1341 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 1400
            +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQR+
Sbjct: 534  KEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRI 593

Query: 1401 GMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLG 1460
            G+AVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSL+RCYSTPSGYLELPDLG
Sbjct: 594  GLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLG 653

Query: 1461 QPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSL 1520
            QPY SAVYSLEEQYLGLALDVDRIKKDQEEE  EDQ PPCPRLSRELLEVVEPEVLQDSL
Sbjct: 654  QPYRSAVYSLEEQYLGLALDVDRIKKDQEEE--EDQGPPCPRLSRELLEVVEPEVLQDSL 711

Query: 1521 DRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 1580
            D     P   L       P    F    +N + F L   +++++G     RGR+  +E +
Sbjct: 712  DVIQLLP-VVLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQ 765

Query: 1581 RGRKEGEE 1588
            R ++EGEE
Sbjct: 766  RRKEEGEE 773



 Score =  360 bits (923), Expect = 2e-98
 Identities = 289/792 (36%), Positives = 376/792 (47%), Gaps = 157/792 (19%)

Query: 2141 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2200
            +EI++Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 15   EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 65

Query: 2201 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPR--------LSRELLEVVEPEVL 2248
               L+EQ   G  L    V ++  + +E+ED+                RE+ +  E +V 
Sbjct: 66   GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVP 125

Query: 2249 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVG-EIEKKG---------- 2297
            +DSL+ C  T S+     DS QP+ +     EE+ V  SL V  E    G          
Sbjct: 126  EDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPV 185

Query: 2298 KGKKRRGRRSKKERRRGRKEGE-------EDQNPPCPRLSRELLDEKGPEVLQDSLDRCY 2350
             G              G    E       E     CP+L+ +       +  +   ++C+
Sbjct: 186  PGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEK------KQQFRSLKEKCF 239

Query: 2351 STPSGCLELT-------DSCQP-----YRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQD 2398
             T   C           + C+       R+     E++        +E+ +Y+ +   Q+
Sbjct: 240  VTQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQE 299

Query: 2399 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLAL 2457
                   REL   +E   L++  D   S       L    +P  S    L+EQ   G  L
Sbjct: 300  -------RELTQLREK--LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL 350

Query: 2458 DVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTP 2503
                ++K     D +++ED         Q    P   RE+ +  E EV +DSL+ C  T 
Sbjct: 351  AQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSP---REMQKAEEKEVPEDSLEECAITC 407

Query: 2504 SSCLEQPDSCQPYGSSFYALEENHVGFSL---------------------DVGEIEKKGK 2542
            S+     DS QP+  +    EE+ V  +L                     D  E E+KG 
Sbjct: 408  SNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGP 467

Query: 2543 GKKRRGRRSKKE----------------------------------------------RR 2556
               R  + S++E                                              R 
Sbjct: 468  VSPRNLQESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRH 527

Query: 2557 RGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYV 2616
            R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYV
Sbjct: 528  RWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYV 587

Query: 2617 LEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 2676
            LEQQ +GLAVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTPSGYL
Sbjct: 588  LEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYL 647

Query: 2677 ELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 2736
            ELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL
Sbjct: 648  ELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 707

Query: 2737 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 2796
            QDSLD     P   L       P    F    +  + F L   +++++G     RGR+  
Sbjct: 708  QDSLDVIQLLP-VVLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEG 761

Query: 2797 KERRRGRKEGEE 2808
            +E +R ++EGEE
Sbjct: 762  EEDQRRKEEGEE 773



 Score =  360 bits (923), Expect = 2e-98
 Identities = 287/794 (36%), Positives = 380/794 (47%), Gaps = 137/794 (17%)

Query: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932
            +EI++Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 15   EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 65

Query: 2933 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPR--------LSRELLEVVEPEVL 2980
               L+EQ   G  L    V ++  + +E+ED+                RE+ +  E +V 
Sbjct: 66   GQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVP 125

Query: 2981 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVG-EIEKKG---------- 3029
            +DSL+ C  T S+     DS QP+ +     EE  V  SL V  E    G          
Sbjct: 126  EDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPV 185

Query: 3030 KGKKRRGRRSKKERRRGRKEGE-------EDQNPPCPRLSRELLDEKGPKVLQDSLDRCY 3082
             G              G    E       E     CP+L+ +    +  K      ++C+
Sbjct: 186  PGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLK------EKCF 239

Query: 3083 STPSGCL----------ELCDSC--QPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQD 3130
             T   C           E C        R+     E++        +E+ +Y+ +   Q+
Sbjct: 240  VTQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQE 299

Query: 3131 PSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC---------LELCDSCQPYRSAFYILE 3181
                +L  +L + +      +   +   TP             +L + C   R A ++++
Sbjct: 300  RELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGC---RLAQHLVQ 356

Query: 3182 QQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 3241
            +       D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S     
Sbjct: 357  KLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGP 413

Query: 3242 PDLGQPYSSAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLS 3287
             D  QP+     + EE  +   L               +   + D EEEE++GP  PR  
Sbjct: 414  YDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR-- 471

Query: 3288 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 3347
              L E  E EV Q+S D  YST S   E+  S Q Y S+F++LEE+ V  ++D+G     
Sbjct: 472  -NLQESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG----- 525

Query: 3348 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 3407
                          R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  
Sbjct: 526  --------------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVY 571

Query: 3408 LELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEV 3467
            L L DSCQPYRSAFYVLEQQ +GLAVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEV
Sbjct: 572  LGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEV 631

Query: 3468 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRS 3527
            LQDSLDRCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVD+I+K            
Sbjct: 632  LQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKD----------- 680

Query: 3528 KKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCY--------STPSMYFEL 3579
                    +E EEDQ PPCPRL+  L+EV E EVLQDSLD            TP+   E+
Sbjct: 681  --------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLPVVLNSLTPASPTEV 732

Query: 3580 PDSFQHYRSVFYSF 3593
            P  F H+R    +F
Sbjct: 733  P--FMHWRKNMLAF 744



 Score =  320 bits (821), Expect = 1e-86
 Identities = 257/726 (35%), Positives = 352/726 (48%), Gaps = 100/726 (13%)

Query: 2871 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2930
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 92   DEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHK 150

Query: 2931 SAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLS 2968
            +   + EE  +  +L VDR       ++                       GP    +  
Sbjct: 151  NIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 210

Query: 2969 RELLEVVE---PEVLQDSL------DRCYSTPSSCL-------EQPDSCQPYGSSFYALE 3012
              +LE+ E   P++ +         ++C+ T  +C         + + C+    S    E
Sbjct: 211  MNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNE 270

Query: 3013 ----EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 3068
                E+ +   L   E  ++ K       R   + R   +EG +        L   L  +
Sbjct: 271  RQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD 330

Query: 3069 KGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED 3128
            +  K     L           +L + C   R A +++++       D DE  + +  E+ 
Sbjct: 331  EPDKSQGQDLQE---------QLAEGC---RLAQHLVQKLSPENDNDDDEDVQVEVAEKV 378

Query: 3129 QDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLA 3188
            Q  S PR   E+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   
Sbjct: 379  QKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDST 435

Query: 3189 VD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYST 3234
            +               + E E   E EE++ P  PR    L + +E EV Q+S D  YST
Sbjct: 436  LIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYST 492

Query: 3235 PSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVV 3294
             S   E     Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  
Sbjct: 493  LSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK 552

Query: 3295 EPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRR 3354
            EPEVLQDSLDRCYSTPS  L   DSCQPY S+FY LE++ +G ++D+ EIEK        
Sbjct: 553  EPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY------- 605

Query: 3355 GRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSC 3414
                        +E EEDQ+P CPRLSRELL EK PEVLQDSLDRCYSTPSG LEL D  
Sbjct: 606  ------------QEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLG 653

Query: 3415 QPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDR 3474
            QPYRSA Y LE+Q++GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLD 
Sbjct: 654  QPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDV 713

Query: 3475 CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRG 3534
                P     L     P         +  L   L  +K++++G     RGR+  +E +R 
Sbjct: 714  IQLLPVVLNSLTP-ASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRR 767

Query: 3535 RKEGEE 3540
            ++EGEE
Sbjct: 768  KEEGEE 773



 Score =  239 bits (611), Expect = 3e-62
 Identities = 209/606 (34%), Positives = 291/606 (48%), Gaps = 83/606 (13%)

Query: 3051 EEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRV 3110
            EED+        RE+   +  KV +DSL+ C  T S     CDS QP+++     E+ +V
Sbjct: 102  EEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKV 161

Query: 3111 GLAVDMDEIEKYQEVEEDQD------PSCPRLSRELLDEKGPEVLQDS-LDRCYSTPSGC 3163
              ++ +D    +   ++  +      P+    +  ++   GP   + + ++        C
Sbjct: 162  NSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLC 221

Query: 3164 LELCDSCQPYRSAFY--ILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEP 3221
             +L +  Q +RS      + Q    LA   ++  KY+E + D   S  R  R+  +EK  
Sbjct: 222  PQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKY-KYEECK-DLIKSMLRNERQFKEEKLA 279

Query: 3222 EVLQDSLD-RCYST--PSGYLELPDL------------------------GQPYSSAVYS 3254
            E L+ + + R Y     S   EL  L                         +P  S    
Sbjct: 280  EQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQD 339

Query: 3255 LEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPEVL 3299
            L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E EV 
Sbjct: 340  LQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVP 396

Query: 3300 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 3359
            +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++
Sbjct: 397  EDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENE 456

Query: 3360 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRS 3419
             +      E EE++ P  PR  +E  +E   EV Q+S D  YST S   E   S Q Y S
Sbjct: 457  SD-----DEEEEEKGPVSPRNLQESEEE---EVPQESWDEGYSTLSIPPERLASYQSYSS 508

Query: 3420 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 3479
             F+ LE+Q V +AVD+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDRCYSTP
Sbjct: 509  TFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTP 568

Query: 3480 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGE 3539
            S YL L D  QPY SA Y LE+Q +GLA+D+D+IEK                    +E E
Sbjct: 569  SVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY-------------------QEVE 609

Query: 3540 EDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHIS 3599
            EDQ+P CPRL+  L+  +E EVLQDSLDRCYSTPS Y ELPD  Q YRS  YS EEQ++ 
Sbjct: 610  EDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLG 669

Query: 3600 FALYVD 3605
             AL VD
Sbjct: 670  LALDVD 675


>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
          Length = 790

 Score = 1328 bits (3438), Expect = 0.0
 Identities = 678/765 (88%), Positives = 705/765 (92%), Gaps = 6/765 (0%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLA 149
           +E++QYKVLVHSQERELTQLREKLREGRDASRSL EHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15  QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 150 EGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAI 209
           EGCRLAQHLVQKLSPENDEDEDEDVQVEE EKVLESSAPREVQKAEESKVPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 210 TCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATN 269
           TCSNSHGPCDS QPHKNIKITFEED+VNS+LVVDRESSHD CQDALNILPVPGPTSSATN
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATN 194

Query: 270 VSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKY 329
           VSMVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFR+LKEKCF+TQ++ FLA QQ KY
Sbjct: 195 VSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKY 254

Query: 330 KYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRD 389
           KYEECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRD
Sbjct: 255 KYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRD 314

Query: 390 ASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV 449
           ASRSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV
Sbjct: 315 ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV 374

Query: 450 AEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDS 509
           AEKVQKSS+PREMQKAEEKEVPEDSLEECAIT SNSHG YDSNQPHRKTKITFEEDKVDS
Sbjct: 375 AEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDS 434

Query: 510 TLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 569
           TLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS
Sbjct: 435 TLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 494

Query: 570 IPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGP 629
           IPPE LASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK P
Sbjct: 495 IPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEP 554

Query: 630 EVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDP 689
           EV QDS DRCYSTPS  L LTDSCQPYRSAFY+LEQQR+GLA+DMDEIEKYQEVEEDQDP
Sbjct: 555 EVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDP 614

Query: 690 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDV 749
           SCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDV
Sbjct: 615 SCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDV 674

Query: 750 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 809
           DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD     P   L       P    
Sbjct: 675 DRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLPV-VLNSLTPASPTEVP 733

Query: 810 FYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 854
           F    +  + F L   +++++G     RGR+  +E +R ++EGEE
Sbjct: 734 FMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKEEGEE 773



 Score =  641 bits (1654), Expect = 0.0
 Identities = 405/800 (50%), Positives = 483/800 (60%), Gaps = 103/800 (12%)

Query: 361  EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420
            +E++QYKVLVH+QERELTQL+EKLREGRDASRSLNEHLQALLTP EPDKSQGQDLQEQLA
Sbjct: 15   QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            EGCRLAQHLVQKLSPEND D+DEDVQVE  EKV +SSAPRE+QKAEE +VPEDSLEECAI
Sbjct: 75   EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 481  TYSNSHGSYDSNQPHRKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 538
            T SNSHG  DS QPH+  KITFEEDKV+S+L+    SSH   +DA++I+P          
Sbjct: 135  TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPV--------- 185

Query: 539  EKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEE-----QQV 593
              GP S            P  S     + L I  ++          F SL+E     Q  
Sbjct: 186  -PGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVA 244

Query: 594  C-MAVDIGRHRWDQVK-------------KEDQEATGPRLSRELLDEKG----------- 628
            C +A    ++++++ K             KE++ A   + + EL   K            
Sbjct: 245  CFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ 304

Query: 629  -PEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRV-GLAI-------------- 672
              E  ++ +D   S       L    +P +S    L++Q   G  +              
Sbjct: 305  LREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN 364

Query: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 365  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 421

Query: 733  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 422  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 478

Query: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838
             EV Q+S D  YST S   E+  S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 479  EEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG------------- 525

Query: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQ
Sbjct: 526  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQ 579

Query: 899  PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
            PYRSAFYVLEQQR+G AVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRC
Sbjct: 580  PYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRC 639

Query: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018
            YSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 640  YSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 699

Query: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078
            EVVEPEVLQDSLD     P   L       P    F    +  + F L   +++++G   
Sbjct: 700  EVVEPEVLQDSLDVIQLLP-VVLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG--- 755

Query: 1079 KRRGRRSKKERRRGRKEGEE 1098
              RGR+  +E +R ++EGEE
Sbjct: 756  --RGRKEGEEDQRRKEEGEE 773



 Score =  455 bits (1170), Expect = e-127
 Identities = 294/591 (49%), Positives = 368/591 (62%), Gaps = 64/591 (10%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINE L PQLAEKKQQFR+LKEKCF+TQ+A FLA +Q KYKY
Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKY 256

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 257 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 316

Query: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
           RSL EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AE
Sbjct: 317 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 376

Query: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +SS+PRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 377 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 436

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           +    SSH E +DA++I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 437 I--GSSSHVEWEDAVHIIP-----ENESDDEEEEEKGPVSPR----NLQESEEEEVPQES 485

Query: 301 -EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQ 359
            ++     ++  +    +L+ + +     +  EE +  +   +   R    +++ ++ ++
Sbjct: 486 WDEGYSTLSIPPE----RLASYQSYSSTFHSLEEQQVCMAVDIGRHRW---DQVKKEDQE 538

Query: 360 AEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQL 419
           A   R  + L+  +E E+      L++  D   S       L    +P +S    L++Q 
Sbjct: 539 ATGPRLSRELLDEKEPEV------LQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQ- 591

Query: 420 AEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLE 476
               R+   +          D DE  + +  E+ Q  S P   RE+   +E EV +DSL+
Sbjct: 592 ----RIGLAV----------DMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLD 637

Query: 477 ECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEE 536
            C  T S      D  QP+R    + EE  +   L               +   + D EE
Sbjct: 638 RCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLAL--------------DVDRIKKDQEE 683

Query: 537 EEEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSST 584
           EE++GP  P   R L E  E EV Q+S D     + + P +L S    S T
Sbjct: 684 EEDQGPPCPRLSRELLEVVEPEVLQDSLD----VIQLLPVVLNSLTPASPT 730



 Score =  415 bits (1067), Expect = e-115
 Identities = 310/736 (42%), Positives = 384/736 (52%), Gaps = 104/736 (14%)

Query: 1398 QRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELP 1457
            Q++    D DE E  Q VEED+        RE+   +E +V +DSL  C  T S      
Sbjct: 85   QKLSPENDEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPC 143

Query: 1458 DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDP----PCPR----------- 1502
            D  QP+ +   + EE  +  +L VDR     E   D  QD     P P            
Sbjct: 144  DSIQPHKNIKITFEEDKVNSSLVVDR-----ESSHDGCQDALNILPVPGPTSSATNVSMV 198

Query: 1503 -----LSRELLEVVEPEV-------LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEN 1550
                 LS E  E+   E+       L +   +  S    C     +C      F A ++N
Sbjct: 199  VSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVAC------FLAKQQN 252

Query: 1551 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEV 1609
               +     E +   K   R  R+ K+E+   + K+ EE +       S+E    +  E 
Sbjct: 253  KYKYE----ECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREK 308

Query: 1610 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQ---------HVGLAV------DMDE 1654
            L++  D   S       L    +P +S    L++Q         H+   +      D DE
Sbjct: 309  LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDE 368

Query: 1655 IEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVY 1714
              + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+     
Sbjct: 369  DVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKI 425

Query: 1715 SLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 1760
            + EE  +   L               +   + D EEEE++GP  PR    L E  E EV 
Sbjct: 426  TFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVP 482

Query: 1761 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 1820
            Q+S D  YST S   E+  S Q Y S+F++LEE  V  ++D+G                 
Sbjct: 483  QESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG----------------- 525

Query: 1821 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 1880
              R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRS
Sbjct: 526  --RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRS 583

Query: 1881 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 1940
            AFYVLEQQ +GLAVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTP
Sbjct: 584  AFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTP 643

Query: 1941 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000
            SGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE
Sbjct: 644  SGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 703

Query: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060
            PEVLQDSLD     P   L       P    F    +N + F L   +++++G     RG
Sbjct: 704  PEVLQDSLDVIQLLPV-VLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RG 757

Query: 2061 RRSKKERRRGRKEGEE 2076
            R+  +E +R ++EGEE
Sbjct: 758  RKEGEEDQRRKEEGEE 773



 Score =  412 bits (1060), Expect = e-114
 Identities = 303/724 (41%), Positives = 379/724 (52%), Gaps = 96/724 (13%)

Query: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 92   DEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHK 150

Query: 1711 SAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLS 1748
            +   + EE  +  +L VDR       ++                       GP    +  
Sbjct: 151  NIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 210

Query: 1749 RELLEVVEP--EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIE 1806
              +LE+ E     L +   +  S    C     +C      F A ++N   +     E +
Sbjct: 211  MNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVAC------FLAKQQNKYKYE----ECK 260

Query: 1807 KKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTP 1865
               K   R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S  
Sbjct: 261  DLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLN 320

Query: 1866 SGCLELTDSCQPYRSAFYVLEQQ---------HVGLAV------DMDEIEKYQEVEEDQD 1910
                 L    +P +S    L++Q         H+   +      D DE  + +  E+ Q 
Sbjct: 321  EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 380

Query: 1911 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 1970
             S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L 
Sbjct: 381  SSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI 437

Query: 1971 --------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2016
                          +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S
Sbjct: 438  GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLS 494

Query: 2017 SCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 2076
               E+  S Q Y S+F++LEE  V  ++D+G                   R R  +  +E
Sbjct: 495  IPPERLASYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKE 535

Query: 2077 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGL 2136
            DQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQ +GL
Sbjct: 536  DQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGL 595

Query: 2137 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 2196
            AVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLELPDLGQP
Sbjct: 596  AVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 655

Query: 2197 YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 2256
            Y SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD   
Sbjct: 656  YRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQ 715

Query: 2257 STPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 2316
              P   L       P    F    +N + F L   +++++G     RGR+  +E +R ++
Sbjct: 716  LLPV-VLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKE 769

Query: 2317 EGEE 2320
            EGEE
Sbjct: 770  EGEE 773



 Score =  412 bits (1060), Expect = e-114
 Identities = 303/724 (41%), Positives = 379/724 (52%), Gaps = 96/724 (13%)

Query: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 92   DEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHK 150

Query: 1955 SAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLS 1992
            +   + EE  +  +L VDR       ++                       GP    +  
Sbjct: 151  NIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 210

Query: 1993 RELLEVVEP--EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIE 2050
              +LE+ E     L +   +  S    C     +C      F A ++N   +     E +
Sbjct: 211  MNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVAC------FLAKQQNKYKYE----ECK 260

Query: 2051 KKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTP 2109
               K   R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S  
Sbjct: 261  DLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLN 320

Query: 2110 SGCLELTDSCQPYRSAFYVLEQQ---------HVGLAV------DMDEIEKYQEVEEDQD 2154
                 L    +P +S    L++Q         H+   +      D DE  + +  E+ Q 
Sbjct: 321  EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 380

Query: 2155 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 2214
             S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L 
Sbjct: 381  SSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI 437

Query: 2215 --------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2260
                          +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S
Sbjct: 438  GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLS 494

Query: 2261 SCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 2320
               E+  S Q Y S+F++LEE  V  ++D+G                   R R  +  +E
Sbjct: 495  IPPERLASYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKE 535

Query: 2321 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGL 2380
            DQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQ +GL
Sbjct: 536  DQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGL 595

Query: 2381 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 2440
            AVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLELPDLGQP
Sbjct: 596  AVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 655

Query: 2441 YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 2500
            Y SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD   
Sbjct: 656  YRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQ 715

Query: 2501 STPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 2560
              P   L       P    F    +N + F L   +++++G     RGR+  +E +R ++
Sbjct: 716  LLPV-VLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKE 769

Query: 2561 EGEE 2564
            EGEE
Sbjct: 770  EGEE 773



 Score =  411 bits (1056), Expect = e-114
 Identities = 308/745 (41%), Positives = 383/745 (51%), Gaps = 111/745 (14%)

Query: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 92   DEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHK 150

Query: 2443 SAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLS 2480
            +   + EE  +  +L VDR       ++                       GP    +  
Sbjct: 151  NIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 210

Query: 2481 RELLEVVEP--EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIE 2538
              +LE+ E     L +   +  S    C     +C      F A ++N   +     E +
Sbjct: 211  MNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVAC------FLAKQQNKYKYE----ECK 260

Query: 2539 KKGKGKKRRGRRSKKERRRGR-KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTP 2597
               K   R  R+ K+E+   + K+ EE +       S+E    +  E L++  D   S  
Sbjct: 261  DLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLN 320

Query: 2598 SGCLELTDSCQPYRSAFYVLEQQ---------HVGLAV------DMDEIEKYQEVEEDQD 2642
                 L    +P +S    L++Q         H+   +      D DE  + +  E+ Q 
Sbjct: 321  EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 380

Query: 2643 PSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 2702
             S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L 
Sbjct: 381  SSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI 437

Query: 2703 --------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2748
                          +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S
Sbjct: 438  GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLS 494

Query: 2749 SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 2808
               E+  S Q Y S+F++LEE+ V  ++D+G                   R R  +  +E
Sbjct: 495  IPPERLASYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKE 535

Query: 2809 DQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGL 2868
            DQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQ +GL
Sbjct: 536  DQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGL 595

Query: 2869 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 2928
            AVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLELPDLGQP
Sbjct: 596  AVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 655

Query: 2929 YSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 2988
            Y SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD   
Sbjct: 656  YRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQ 715

Query: 2989 STPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRK 3048
              P   L       P    F    +  + F L   +++++G               RGRK
Sbjct: 716  LLP-VVLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG---------------RGRK 759

Query: 3049 EGEEDQNPPCPRLSRELLDEKGPKV 3073
            EGEEDQ     R   E  ++KG K+
Sbjct: 760  EGEEDQ-----RRKEEGEEKKGKKI 779



 Score =  405 bits (1040), Expect = e-112
 Identities = 316/835 (37%), Positives = 413/835 (49%), Gaps = 124/835 (14%)

Query: 566  STLSIPPEMLASYQSYSSTFHSLEEQ--QVCMAVDIGRHRWDQVKKEDQEATGPRLSREL 623
            ST  +P +     Q Y    HS E +  Q+   +  GR     + +  Q    P      
Sbjct: 5    STGRLPGQPTQEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP------ 58

Query: 624  LDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEV 683
             DE      QD Q+          +L + C   R A +++  Q++    D DE E  Q V
Sbjct: 59   -DEPDKSQGQDLQE----------QLAEGC---RLAQHLV--QKLSPENDEDEDEDVQ-V 101

Query: 684  EEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL 743
            EED+        RE+   +E +V +DSL+ C  T S      D  QP+ +   + EE  +
Sbjct: 102  EEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKV 161

Query: 744  GLALDVDRIKKDQEEEE---------------------DQGP-PCPRLSRELLEVVE--- 778
              +L VDR       ++                       GP    +    +LE+ E   
Sbjct: 162  NSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLC 221

Query: 779  PEVLQDSL------DRCYSTPSSCL-------EQPDSCQPYGSSFYALE----EKHVGFS 821
            P++ +         ++C+ T  +C         + + C+    S    E    E+ +   
Sbjct: 222  PQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQ 281

Query: 822  LDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLD 881
            L   E  ++ K       R   + R   +EG +        L   L  ++  +     L 
Sbjct: 282  LKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQ 341

Query: 882  RCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRE 941
                      +L + C   R A +++++       D DE  + +  E+ Q  S PR   E
Sbjct: 342  E---------QLAEGC---RLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---E 386

Query: 942  LLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD--------- 992
            +   +E EV +DSL+ C  T S      D  QP+     + EE  +   L          
Sbjct: 387  MQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWE 446

Query: 993  -----VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSC 1047
                 +   + D EEEE++GP  PR    L E  E EV Q+S D  YST S   E+  S 
Sbjct: 447  DAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPERLASY 503

Query: 1048 QPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRL 1107
            Q Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    PRL
Sbjct: 504  QSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGPRL 544

Query: 1108 SRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEK 1167
            SRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQR+G AVDMDEIEK
Sbjct: 545  SRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEK 604

Query: 1168 YQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLE 1227
            YQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLELPDLGQPY SAVYSLE
Sbjct: 605  YQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLE 664

Query: 1228 EQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQ 1287
            EQYLGLALDVDRIKKD+EEEEDQ PPCPRLSRELLEVV PEVLQDSLD     P   L  
Sbjct: 665  EQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLPV-VLNS 723

Query: 1288 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 1342
                 P    F    +  + F L   +++++G     RGR+  +E +R ++EGEE
Sbjct: 724  LTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRRKEEGEE 773



 Score =  402 bits (1034), Expect = e-111
 Identities = 306/799 (38%), Positives = 408/799 (51%), Gaps = 98/799 (12%)

Query: 2630 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 2689
            EI++Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S  
Sbjct: 16   EIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQG 66

Query: 2690 YSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPR--------LSRELLEVVEPEVLQ 2737
              L+EQ   G  L    V ++  + +E+ED+                RE+ +  E +V +
Sbjct: 67   QDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPE 126

Query: 2738 DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVG-EIEKKG----------K 2786
            DSL+ C  T S+     DS QP+ +     EE  V  SL V  E    G           
Sbjct: 127  DSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVP 186

Query: 2787 GKKRRGRRSKKERRRGRKEGE-------EDQNPPCPRLSRELLDEKGPEVLQDSLDRCYS 2839
            G              G    E       E     CP+L+ +       +  +   ++C+ 
Sbjct: 187  GPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEK------KQQFRSLKEKCFV 240

Query: 2840 TPSGCLELT-------DSCQPYRSAFYVLEQQ--HVGLAVDM---DEIEKYQEVEEDQDP 2887
            T   C           + C+    +    E+Q     LA  +   +E+ +Y+ +   Q+ 
Sbjct: 241  TQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQER 300

Query: 2888 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLALD 2946
               +L  +L + ++     +   +   TP          +P  S    L+EQ   G  L 
Sbjct: 301  ELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQGQDLQEQLAEGCRLA 351

Query: 2947 VDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2992
               ++K     D +++ED         Q    PR   E+ +  E EV +DSL+ C  T S
Sbjct: 352  QHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCS 408

Query: 2993 SCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEE 3052
            +     DS QP+  +    EE  V  +L       + +        ++ +      E EE
Sbjct: 409  NSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD-----DEEEE 463

Query: 3053 DQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGL 3112
            ++ P  PR  +E  +E+ P   Q+S D  YST S   E   S Q Y S F+ LE+Q+V +
Sbjct: 464  EKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCM 520

Query: 3113 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQP 3172
            AVD+      Q  +EDQ+ + PRLSRELLDEK PEVLQDSLDRCYSTPS  L L DSCQP
Sbjct: 521  AVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQP 580

Query: 3173 YRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCY 3232
            YRSAFY+LEQQR+GLAVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCY
Sbjct: 581  YRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCY 640

Query: 3233 STPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLE 3292
            STPSGYLELPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLE
Sbjct: 641  STPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLE 700

Query: 3293 VVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKK 3352
            VVEPEVLQDSLD     P   L       P    F    +  + F L   +++++G    
Sbjct: 701  VVEPEVLQDSLDVIQLLPV-VLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG---- 755

Query: 3353 RRGRRSKKERRRGRKEGEE 3371
             RGR+  +E +R ++EGEE
Sbjct: 756  -RGRKEGEEDQRRKEEGEE 773



 Score =  398 bits (1023), Expect = e-110
 Identities = 293/728 (40%), Positives = 377/728 (51%), Gaps = 102/728 (14%)

Query: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 92   DEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHK 150

Query: 977  SAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLS 1014
            +   + EE  +  +L VDR       ++                       GP    +  
Sbjct: 151  NIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 210

Query: 1015 RELLEVVE---PEVLQDSL------DRCYSTPSSCL-------EQPDSCQPYGSSFYALE 1058
              +LE+ E   P++ +         ++C+ T  +C         + + C+    S    E
Sbjct: 211  MNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNE 270

Query: 1059 ----EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 1114
                E+ +   L   E  ++ K       R   + R   +EG +        L   L  +
Sbjct: 271  RQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD 330

Query: 1115 KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEED 1174
            +  +     L           +L + C   R A +++++       D DE  + +  E+ 
Sbjct: 331  EPDKSQGQDLQE---------QLAEGC---RLAQHLVQKLSPENDNDDDEDVQVEVAEKV 378

Query: 1175 QDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 1234
            Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+     + EE  +   
Sbjct: 379  QKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDST 435

Query: 1235 LD--------------VDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYST 1280
            L               +   + D+EEEE++ P  PR    L E    EV Q+S D  YST
Sbjct: 436  LIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYST 492

Query: 1281 PSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEG 1340
             S   E+  S Q Y S+F++LEE+ V  ++D+G                   R R  +  
Sbjct: 493  LSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVK 533

Query: 1341 EEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 1400
            +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVLEQQR+
Sbjct: 534  KEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRI 593

Query: 1401 GMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLG 1460
            G+AVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSL+RCYSTPSGYLELPDLG
Sbjct: 594  GLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLG 653

Query: 1461 QPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSL 1520
            QPY SAVYSLEEQYLGLALDVDRIKKDQEEEED  Q PPCPRLSRELLEVVEPEVLQDSL
Sbjct: 654  QPYRSAVYSLEEQYLGLALDVDRIKKDQEEEED--QGPPCPRLSRELLEVVEPEVLQDSL 711

Query: 1521 DRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 1580
            D     P   L       P    F    +N + F L   +++++G     RGR+  +E +
Sbjct: 712  DVIQLLPV-VLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQ 765

Query: 1581 RGRKEGEE 1588
            R ++EGEE
Sbjct: 766  RRKEEGEE 773



 Score =  359 bits (921), Expect = 3e-98
 Identities = 289/791 (36%), Positives = 375/791 (47%), Gaps = 157/791 (19%)

Query: 2142 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 2201
            EI++Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S  
Sbjct: 16   EIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQG 66

Query: 2202 YSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPR--------LSRELLEVVEPEVLQ 2249
              L+EQ   G  L    V ++  + +E+ED+                RE+ +  E +V +
Sbjct: 67   QDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPE 126

Query: 2250 DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVG-EIEKKG----------K 2298
            DSL+ C  T S+     DS QP+ +     EE+ V  SL V  E    G           
Sbjct: 127  DSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVP 186

Query: 2299 GKKRRGRRSKKERRRGRKEGE-------EDQNPPCPRLSRELLDEKGPEVLQDSLDRCYS 2351
            G              G    E       E     CP+L+ +       +  +   ++C+ 
Sbjct: 187  GPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEK------KQQFRSLKEKCFV 240

Query: 2352 TPSGCLELT-------DSCQP-----YRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDP 2399
            T   C           + C+       R+     E++        +E+ +Y+ +   Q+ 
Sbjct: 241  TQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQE- 299

Query: 2400 SCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYL-GLALD 2458
                  REL   +E   L++  D   S       L    +P  S    L+EQ   G  L 
Sbjct: 300  ------RELTQLREK--LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLA 351

Query: 2459 VDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPS 2504
               ++K     D +++ED         Q    P   RE+ +  E EV +DSL+ C  T S
Sbjct: 352  QHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSP---REMQKAEEKEVPEDSLEECAITCS 408

Query: 2505 SCLEQPDSCQPYGSSFYALEENHVGFSL---------------------DVGEIEKKGKG 2543
            +     DS QP+  +    EE+ V  +L                     D  E E+KG  
Sbjct: 409  NSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPV 468

Query: 2544 KKRRGRRSKKE----------------------------------------------RRR 2557
              R  + S++E                                              R R
Sbjct: 469  SPRNLQESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHR 528

Query: 2558 GRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVL 2617
              +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L LTDSCQPYRSAFYVL
Sbjct: 529  WDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVL 588

Query: 2618 EQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLE 2677
            EQQ +GLAVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVLQDSLDRCYSTPSGYLE
Sbjct: 589  EQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLE 648

Query: 2678 LPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQ 2737
            LPDLGQPY SAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQ
Sbjct: 649  LPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQ 708

Query: 2738 DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK 2797
            DSLD     P   L       P    F    +  + F L   +++++G     RGR+  +
Sbjct: 709  DSLDVIQLLP-VVLNSLTPASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGE 762

Query: 2798 ERRRGRKEGEE 2808
            E +R ++EGEE
Sbjct: 763  EDQRRKEEGEE 773



 Score =  359 bits (921), Expect = 3e-98
 Identities = 287/793 (36%), Positives = 379/793 (47%), Gaps = 137/793 (17%)

Query: 2874 EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 2933
            EI++Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S  
Sbjct: 16   EIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQG 66

Query: 2934 YSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPR--------LSRELLEVVEPEVLQ 2981
              L+EQ   G  L    V ++  + +E+ED+                RE+ +  E +V +
Sbjct: 67   QDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPE 126

Query: 2982 DSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVG-EIEKKG----------K 3030
            DSL+ C  T S+     DS QP+ +     EE  V  SL V  E    G           
Sbjct: 127  DSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVP 186

Query: 3031 GKKRRGRRSKKERRRGRKEGE-------EDQNPPCPRLSRELLDEKGPKVLQDSLDRCYS 3083
            G              G    E       E     CP+L+ +    +  K      ++C+ 
Sbjct: 187  GPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLK------EKCFV 240

Query: 3084 TPSGCL----------ELCDSC--QPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDP 3131
            T   C           E C        R+     E++        +E+ +Y+ +   Q+ 
Sbjct: 241  TQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQER 300

Query: 3132 SCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC---------LELCDSCQPYRSAFYILEQ 3182
               +L  +L + +      +   +   TP             +L + C   R A +++++
Sbjct: 301  ELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGC---RLAQHLVQK 357

Query: 3183 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 3242
                   D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      
Sbjct: 358  LSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPY 414

Query: 3243 DLGQPYSSAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSR 3288
            D  QP+     + EE  +   L               +   + D EEEE++GP  PR   
Sbjct: 415  DSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--- 471

Query: 3289 ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKG 3348
             L E  E EV Q+S D  YST S   E+  S Q Y S+F++LEE+ V  ++D+G      
Sbjct: 472  NLQESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIG------ 525

Query: 3349 KGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCL 3408
                         R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPS  L
Sbjct: 526  -------------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYL 572

Query: 3409 ELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3468
             L DSCQPYRSAFYVLEQQ +GLAVDMDEIEKYQEVEEDQDPSCPRLSRELL EKEPEVL
Sbjct: 573  GLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVL 632

Query: 3469 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSK 3528
            QDSLDRCYSTPSGYLELPDLGQPY SAVYSLEEQYLGLALDVD+I+K             
Sbjct: 633  QDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKD------------ 680

Query: 3529 KERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCY--------STPSMYFELP 3580
                   +E EEDQ PPCPRL+  L+EV E EVLQDSLD            TP+   E+P
Sbjct: 681  -------QEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQLLPVVLNSLTPASPTEVP 733

Query: 3581 DSFQHYRSVFYSF 3593
              F H+R    +F
Sbjct: 734  --FMHWRKNMLAF 744



 Score =  320 bits (821), Expect = 1e-86
 Identities = 257/726 (35%), Positives = 352/726 (48%), Gaps = 100/726 (13%)

Query: 2871 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2930
            D DE E  Q VEED+        RE+   +E +V +DSL+ C  T S      D  QP+ 
Sbjct: 92   DEDEDEDVQ-VEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHK 150

Query: 2931 SAVYSLEEQYLGLALDVDRIKKDQEEEE---------------------DQGP-PCPRLS 2968
            +   + EE  +  +L VDR       ++                       GP    +  
Sbjct: 151  NIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE 210

Query: 2969 RELLEVVE---PEVLQDSL------DRCYSTPSSCL-------EQPDSCQPYGSSFYALE 3012
              +LE+ E   P++ +         ++C+ T  +C         + + C+    S    E
Sbjct: 211  MNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNE 270

Query: 3013 ----EKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 3068
                E+ +   L   E  ++ K       R   + R   +EG +        L   L  +
Sbjct: 271  RQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD 330

Query: 3069 KGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEED 3128
            +  K     L           +L + C   R A +++++       D DE  + +  E+ 
Sbjct: 331  EPDKSQGQDLQE---------QLAEGC---RLAQHLVQKLSPENDNDDDEDVQVEVAEKV 378

Query: 3129 QDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLA 3188
            Q  S PR   E+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   
Sbjct: 379  QKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDST 435

Query: 3189 VD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYST 3234
            +               + E E   E EE++ P  PR    L + +E EV Q+S D  YST
Sbjct: 436  LIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEEEEVPQESWDEGYST 492

Query: 3235 PSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVV 3294
             S   E     Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ    PRLSRELL+  
Sbjct: 493  LSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK 552

Query: 3295 EPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRR 3354
            EPEVLQDSLDRCYSTPS  L   DSCQPY S+FY LE++ +G ++D+ EIEK        
Sbjct: 553  EPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY------- 605

Query: 3355 GRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSC 3414
                        +E EEDQ+P CPRLSRELL EK PEVLQDSLDRCYSTPSG LEL D  
Sbjct: 606  ------------QEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLG 653

Query: 3415 QPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDR 3474
            QPYRSA Y LE+Q++GLA+D+D I+K QE EEDQ P CPRLSRELL+  EPEVLQDSLD 
Sbjct: 654  QPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDV 713

Query: 3475 CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRG 3534
                P     L     P         +  L   L  +K++++G     RGR+  +E +R 
Sbjct: 714  IQLLPVVLNSLTP-ASPTEVPFMHWRKNMLAFLLTWEKLKRRG-----RGRKEGEEDQRR 767

Query: 3535 RKEGEE 3540
            ++EGEE
Sbjct: 768  KEEGEE 773



 Score =  239 bits (611), Expect = 3e-62
 Identities = 209/606 (34%), Positives = 291/606 (48%), Gaps = 83/606 (13%)

Query: 3051 EEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRV 3110
            EED+        RE+   +  KV +DSL+ C  T S     CDS QP+++     E+ +V
Sbjct: 102  EEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKV 161

Query: 3111 GLAVDMDEIEKYQEVEEDQD------PSCPRLSRELLDEKGPEVLQDS-LDRCYSTPSGC 3163
              ++ +D    +   ++  +      P+    +  ++   GP   + + ++        C
Sbjct: 162  NSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLC 221

Query: 3164 LELCDSCQPYRSAFY--ILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEP 3221
             +L +  Q +RS      + Q    LA   ++  KY+E + D   S  R  R+  +EK  
Sbjct: 222  PQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKY-KYEECK-DLIKSMLRNERQFKEEKLA 279

Query: 3222 EVLQDSLD-RCYST--PSGYLELPDL------------------------GQPYSSAVYS 3254
            E L+ + + R Y     S   EL  L                         +P  S    
Sbjct: 280  EQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQD 339

Query: 3255 LEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEPEVL 3299
            L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E EV 
Sbjct: 340  LQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVP 396

Query: 3300 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 3359
            +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++
Sbjct: 397  EDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENE 456

Query: 3360 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRS 3419
             +      E EE++ P  PR  +E  +E   EV Q+S D  YST S   E   S Q Y S
Sbjct: 457  SD-----DEEEEEKGPVSPRNLQESEEE---EVPQESWDEGYSTLSIPPERLASYQSYSS 508

Query: 3420 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 3479
             F+ LE+Q V +AVD+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDRCYSTP
Sbjct: 509  TFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTP 568

Query: 3480 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGE 3539
            S YL L D  QPY SA Y LE+Q +GLA+D+D+IEK                    +E E
Sbjct: 569  SVYLGLTDSCQPYRSAFYVLEQQRIGLAVDMDEIEKY-------------------QEVE 609

Query: 3540 EDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHIS 3599
            EDQ+P CPRL+  L+  +E EVLQDSLDRCYSTPS Y ELPD  Q YRS  YS EEQ++ 
Sbjct: 610  EDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLG 669

Query: 3600 FALYVD 3605
             AL VD
Sbjct: 670  LALDVD 675


>gi|157266285 hypothetical protein LOC728936 [Homo sapiens]
          Length = 670

 Score = 1214 bits (3141), Expect = 0.0
 Identities = 606/648 (93%), Positives = 622/648 (95%), Gaps = 1/648 (0%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKY 331
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL+GFLAN+QKKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDAS 391
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 392 RSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 451
           RSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511
           KVQKSSAPREMQKAEEKEVPEDSLEECAIT SNSHG YDSNQPH+KTKITFEEDKVDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 512 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 571
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300

Query: 572 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631
           PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360

Query: 632 FQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSC 691
            QDS DRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAIDMDEIEKYQEVEEDQDPSC
Sbjct: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420

Query: 692 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 751
           PRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDR
Sbjct: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 480

Query: 752 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 811
           IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540

Query: 812 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 871
           ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ +
Sbjct: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVE 599

Query: 872 GPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMD 919
            PEVLQDSLDRCYST S   EL DS Q YRS FY  E++ + FA+ +D
Sbjct: 600 EPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  610 bits (1572), Expect = e-173
 Identities = 332/505 (65%), Positives = 368/505 (72%), Gaps = 40/505 (7%)

Query: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 733  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 899  PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
            PYRSAFYVLEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + PEVLQDSLDRCYST S   EL 
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622

Query: 1139 DSCQPYRSAFYVLEQQRVGFAVDMD 1163
            DS Q YRS FY  E++ + FA+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  610 bits (1572), Expect = e-173
 Identities = 332/505 (65%), Positives = 367/505 (72%), Gaps = 40/505 (7%)

Query: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 2443 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2488
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 2489 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2548
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 2549 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2608
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 2609 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2668
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 2669 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2728
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 2729 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2788
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 2789 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2848
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + PEVLQDSLDRCYST S   EL 
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622

Query: 2849 DSCQPYRSAFYVLEQQHVGLAVDMD 2873
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  608 bits (1567), Expect = e-173
 Identities = 331/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)

Query: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 1711 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 1877 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1936
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 1937 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1996
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 1997 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2056
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 2057 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2116
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + PEVLQDSLDRCYST S   EL 
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622

Query: 2117 DSCQPYRSAFYVLEQQHVGLAVDMD 2141
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  608 bits (1567), Expect = e-173
 Identities = 331/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)

Query: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 1955 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 2061 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2120
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 2121 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2180
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 2181 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2240
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 2241 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2300
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 2301 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2360
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + PEVLQDSLDRCYST S   EL 
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622

Query: 2361 DSCQPYRSAFYVLEQQHVGLAVDMD 2385
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  608 bits (1567), Expect = e-173
 Identities = 331/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)

Query: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 2199 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2244
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 2245 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2304
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 2305 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2364
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 2365 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2424
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 2425 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2484
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 2485 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2544
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 2545 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2604
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + PEVLQDSLDRCYST S   EL 
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622

Query: 2605 DSCQPYRSAFYVLEQQHVGLAVDMD 2629
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  605 bits (1559), Expect = e-172
 Identities = 330/505 (65%), Positives = 367/505 (72%), Gaps = 40/505 (7%)

Query: 2627 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2686
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 2687 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2732
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 2733 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2792
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 2793 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2852
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 2853 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2912
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 2913 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2972
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 2973 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 3032
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 3033 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELC 3092
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + P+VLQDSLDRCYST S   EL 
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622

Query: 3093 DSCQPYRSAFYVLEQQRVGLAVDMD 3117
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  604 bits (1557), Expect = e-172
 Identities = 330/505 (65%), Positives = 367/505 (72%), Gaps = 38/505 (7%)

Query: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYS 1464
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL  C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 1465 SAVYSLEEQYLGLAL----------DVDRI--KKDQEEEEDEDQDPPCPRLSRELLEVVE 1512
                + EE  +   L          D   I  + + ++EE+E++ P  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 1513 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1572
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 1573 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1632
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 1633 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1692
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 1693 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1752
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 1753 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 1812
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 1813 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1872
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + PEVLQDSLDRCYST S   EL 
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622

Query: 1873 DSCQPYRSAFYVLEQQHVGLAVDMD 1897
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  603 bits (1556), Expect = e-172
 Identities = 341/579 (58%), Positives = 402/579 (69%), Gaps = 36/579 (6%)

Query: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 2933 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2977
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEK 197

Query: 2978 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3037
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 198  EVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 3038 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQP 3097
             ++ +      E EE++ P  PR  +E  +E+ P   Q+S D  YST S   E+  S Q 
Sbjct: 258  ENESD-----DEEEEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYQS 309

Query: 3098 YRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCY 3157
            Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLSRELLDEK PEVLQDSLDRCY
Sbjct: 310  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369

Query: 3158 STPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 3217
            STPSGCLEL DSCQPYRSAFY+LEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 370  STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429

Query: 3218 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 3277
            EKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE
Sbjct: 430  EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 489

Query: 3278 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 3337
            DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 490  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549

Query: 3338 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 3397
            SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + PEVLQDSL
Sbjct: 550  SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSL 608

Query: 3398 DRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436
            DRCYST S   EL DS Q YRS FY  E++H+  A+ +D
Sbjct: 609  DRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  601 bits (1550), Expect = e-171
 Identities = 328/505 (64%), Positives = 365/505 (72%), Gaps = 40/505 (7%)

Query: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 977  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1022
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 1143 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202
            PYRSAFYVLEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELL 1262
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD+EEEEDQ PPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 1263 EVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322
            EVV PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1382
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + PEVLQDSLDRCYST S   EL 
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622

Query: 1383 DSCQPYRSAFYVLEQQRVGMAVDMD 1407
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  595 bits (1535), Expect = e-169
 Identities = 327/507 (64%), Positives = 366/507 (72%), Gaps = 42/507 (8%)

Query: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 1221 SAVYSLEEQYLGLALD--------------VDRIKKDEEEEEDQDPPCPRLSRELLEVVA 1266
                + EE  +   L               +   + D+EEEE++ P  PR    L E   
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1386
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 1387 PYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRC 1446
            PYRSAFYVLEQQRVG+A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL+RC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 1447 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRE 1506
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEE  EDQ PPCPRLSRE
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEE--EDQGPPCPRLSRE 501

Query: 1507 LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGK 1566
            LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGK
Sbjct: 502  LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK 561

Query: 1567 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 1626
            GKKRRGRRSKK+RRRGRKEGE+D NPPCPRL+  L++ + PEVLQDSLDRCYST S   E
Sbjct: 562  GKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFE 620

Query: 1627 LTDSCQPYRSAFYVLEQQHVGLAVDMD 1653
            L DS Q YRS FY  E++H+  A+ +D
Sbjct: 621  LPDSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  574 bits (1479), Expect = e-163
 Identities = 319/528 (60%), Positives = 372/528 (70%), Gaps = 40/528 (7%)

Query: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174
            D DE  + +  E+ Q  S PR   E+   +  EV +DSL+ C  T S      DS QP++
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 3175 SAFYILEQQRVGLAVD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKE 3220
                  E+ +V   +               + E E   E EE++ P  PR    L + +E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 3221 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 3280
             EV Q+S D  YST S   E+    Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ 
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 342

Query: 3281 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 3340
               PRLSRELL+  EPEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D
Sbjct: 343  ATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAID 402

Query: 3341 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRC 3400
            + EIEK                    +E EEDQ+P CPRLSRELLDEK PEVLQDSLDRC
Sbjct: 403  MDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 3401 YSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 3460
            YSTPS  LEL D  QPY SA Y LE+Q++GLA+D+D I+K QE EEDQ P CPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 3461 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGK 3520
            +  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV +IEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 3521 KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELP 3580
            KRRGRRSKK+RRRGRKEGE+D NPPCPRLNGVLMEVEE EVLQDSLDRCYST SMYFELP
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELP 622

Query: 3581 DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 3628
            DSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 670



 Score =  547 bits (1410), Expect = e-155
 Identities = 349/711 (49%), Positives = 421/711 (59%), Gaps = 100/711 (14%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINE LRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
           RSL EHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +SSAPRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPHK  KITFEED+V+STL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGPLSSEKAEMNILE 290
           +    SSH E +DA++I+P            GP S            P  S     + L 
Sbjct: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 298

Query: 291 INEKLRPQLAEKKQQFRNLKEK--CFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQF 348
           I  ++          F +L+E+  C    +         ++++++ K             
Sbjct: 299 IPPEMLASYQSYSSTFHSLEEQQVCMAVDIG--------RHRWDQVK------------- 337

Query: 349 KEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPD 408
           KE++ A   + + EL          E+E     E L++  D   S       L    +P 
Sbjct: 338 KEDQEATGPRLSREL--------LDEKE----PEVLQDSLDRCYSTPSGCLELTDSCQPY 385

Query: 409 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP---REMQKA 465
           +S    L++Q   G  +              D DE  + +  E+ Q  S P   RE+   
Sbjct: 386 RSAFYVLEQQRV-GLAI--------------DMDEIEKYQEVEEDQDPSCPRLSRELLDE 430

Query: 466 EEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVH 525
           +E EV +DSL+ C  T S+     D  QP+     + EE  +   L              
Sbjct: 431 KEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL-------------- 476

Query: 526 IIPENESDDEEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYS 582
            +   + D EEEE++GP  P   R L E  E EV Q+S D  YST S   E   S Q Y 
Sbjct: 477 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 536

Query: 583 STFHSLEEQQVCMAVDIG------------------RHRWDQVKKEDQEATGPRLSRELL 624
           S+F++LEE+ V  ++D+G                  + R  + + ED     PRL+  L+
Sbjct: 537 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLM 596

Query: 625 DEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMD 675
           + + PEV QDS DRCYST S   EL DS Q YRS FY  E++ +  A+ +D
Sbjct: 597 EVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYVD 647


>gi|29789405 hypothetical protein LOC284565 [Homo sapiens]
          Length = 670

 Score = 1211 bits (3132), Expect = 0.0
 Identities = 605/648 (93%), Positives = 620/648 (95%), Gaps = 1/648 (0%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKY 331
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL+GFLAN+QKKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDAS 391
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 392 RSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 451
           RSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511
           KVQKSSAPREMQKAEEKEVPEDSLEECAIT SNSHG YDSNQPH+KTKITFEEDKVDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 512 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 571
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIP 300

Query: 572 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEV 631
           PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEK PEV
Sbjct: 301 PEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEV 360

Query: 632 FQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSC 691
            QDS DRCYSTPSGCLELTDSCQPYRSAFY+LEQQRVGLAIDMDEIEKYQEVEEDQDPSC
Sbjct: 361 LQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSC 420

Query: 692 PRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR 751
           PRLSRELLDEKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDR
Sbjct: 421 PRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDR 480

Query: 752 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 811
           IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY
Sbjct: 481 IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFY 540

Query: 812 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEK 871
           ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ +
Sbjct: 541 ALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVE 599

Query: 872 GPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMD 919
            PEVLQDSLDRCYSTPS   E  DS Q YRS FY  E++ + FA+ +D
Sbjct: 600 EPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  606 bits (1563), Expect = e-172
 Identities = 331/505 (65%), Positives = 366/505 (72%), Gaps = 40/505 (7%)

Query: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 733  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 899  PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
            PYRSAFYVLEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1078
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 1079 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1138
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622

Query: 1139 DSCQPYRSAFYVLEQQRVGFAVDMD 1163
            DS Q YRS FY  E++ + FA+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  606 bits (1563), Expect = e-172
 Identities = 331/505 (65%), Positives = 365/505 (72%), Gaps = 40/505 (7%)

Query: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 2443 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2488
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 2489 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2548
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 2549 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2608
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 2609 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2668
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 2669 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2728
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 2729 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 2788
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 2789 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2848
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622

Query: 2849 DSCQPYRSAFYVLEQQHVGLAVDMD 2873
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  604 bits (1558), Expect = e-172
 Identities = 330/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 1711 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 1877 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1936
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 1937 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1996
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 1997 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2056
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 2057 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2116
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622

Query: 2117 DSCQPYRSAFYVLEQQHVGLAVDMD 2141
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  604 bits (1558), Expect = e-172
 Identities = 330/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 1955 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 2061 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2120
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 2121 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2180
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 2181 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2240
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 2241 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2300
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 2301 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2360
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622

Query: 2361 DSCQPYRSAFYVLEQQHVGLAVDMD 2385
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  604 bits (1558), Expect = e-172
 Identities = 330/505 (65%), Positives = 364/505 (72%), Gaps = 40/505 (7%)

Query: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 2199 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2244
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 2245 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2304
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 2305 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2364
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 2365 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2424
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 2425 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2484
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 2485 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 2544
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 2545 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 2604
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622

Query: 2605 DSCQPYRSAFYVLEQQHVGLAVDMD 2629
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  601 bits (1550), Expect = e-171
 Identities = 329/505 (65%), Positives = 365/505 (72%), Gaps = 40/505 (7%)

Query: 2627 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2686
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 2687 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2732
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 2733 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2792
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 2793 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2852
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 2853 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2912
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 2913 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2972
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 2973 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 3032
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 3033 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELC 3092
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + P+VLQDSLDRCYSTPS   E  
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622

Query: 3093 DSCQPYRSAFYVLEQQRVGLAVDMD 3117
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  600 bits (1548), Expect = e-171
 Identities = 329/505 (65%), Positives = 365/505 (72%), Gaps = 38/505 (7%)

Query: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYS 1464
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL  C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 1465 SAVYSLEEQYLGLAL----------DVDRI--KKDQEEEEDEDQDPPCPRLSRELLEVVE 1512
                + EE  +   L          D   I  + + ++EE+E++ P  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 1513 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1572
             EV Q+S D  YST S   E   S Q Y S+F++LEE  V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 1573 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1632
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 1633 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1692
            PYRSAFYVLEQQ VGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 1693 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1752
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEEDQGPPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 1753 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGK 1812
            EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 1813 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1872
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622

Query: 1873 DSCQPYRSAFYVLEQQHVGLAVDMD 1897
            DS Q YRS FY  E++H+  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  600 bits (1547), Expect = e-171
 Identities = 340/579 (58%), Positives = 400/579 (69%), Gaps = 36/579 (6%)

Query: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 2933 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2977
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEK 197

Query: 2978 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3037
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 198  EVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 3038 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQP 3097
             ++ +      E EE++ P  PR  +E  +E+ P   Q+S D  YST S   E+  S Q 
Sbjct: 258  ENESD-----DEEEEEKGPVSPRNLQESEEEEVP---QESWDEGYSTLSIPPEMLASYQS 309

Query: 3098 YRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCY 3157
            Y S F+ LE+Q+V +AVD+      Q  +EDQ+ + PRLSRELLDEK PEVLQDSLDRCY
Sbjct: 310  YSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCY 369

Query: 3158 STPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLD 3217
            STPSGCLEL DSCQPYRSAFY+LEQQRVGLA+DMDEIEKYQEVEEDQDPSCPRLSRELLD
Sbjct: 370  STPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLD 429

Query: 3218 EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEE 3277
            EKEPEVLQDSLDRCYSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEEE
Sbjct: 430  EKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEE 489

Query: 3278 DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 3337
            DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF
Sbjct: 490  DQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGF 549

Query: 3338 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSL 3397
            SLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSL
Sbjct: 550  SLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSL 608

Query: 3398 DRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436
            DRCYSTPS   E  DS Q YRS FY  E++H+  A+ +D
Sbjct: 609  DRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  598 bits (1541), Expect = e-170
 Identities = 327/505 (64%), Positives = 363/505 (71%), Gaps = 40/505 (7%)

Query: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 977  SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1022
                + EE  +   L               +   + D EEEE++GP  PR    L E  E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 1143 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202
            PYRSAFYVLEQQRVG A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELL 1262
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKD+EEEEDQ PPCPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 1263 EVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 1322
            EVV PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 1323 KRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELT 1382
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E  
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622

Query: 1383 DSCQPYRSAFYVLEQQRVGMAVDMD 1407
            DS Q YRS FY  E++ +  A+ +D
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  592 bits (1526), Expect = e-168
 Identities = 326/507 (64%), Positives = 364/507 (71%), Gaps = 42/507 (8%)

Query: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 1221 SAVYSLEEQYLGLALD--------------VDRIKKDEEEEEDQDPPCPRLSRELLEVVA 1266
                + EE  +   L               +   + D+EEEE++ P  PR    L E   
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326
             EV Q+S D  YST S   E   S Q Y S+F++LEE+ V  ++D+G             
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIG------------- 329

Query: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1386
                  R R  +  +EDQ    PRLSRELLDEK PEVLQDSLDRCYSTPSGCLELTDSCQ
Sbjct: 330  ------RHRWDQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQ 383

Query: 1387 PYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRC 1446
            PYRSAFYVLEQQRVG+A+DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL+RC
Sbjct: 384  PYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 1447 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRE 1506
            YSTPS YLELPDLGQPYSSAVYSLEEQYLGLAL VDRIKKDQEEE  EDQ PPCPRLSRE
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEE--EDQGPPCPRLSRE 501

Query: 1507 LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGK 1566
            LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGK
Sbjct: 502  LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGK 561

Query: 1567 GKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLE 1626
            GKKRRGRRSKK+RRRGRKEGE+D NPPCPRL   L++ + PEVLQDSLDRCYSTPS   E
Sbjct: 562  GKKRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFE 620

Query: 1627 LTDSCQPYRSAFYVLEQQHVGLAVDMD 1653
              DS Q YRS FY  E++H+  A+ +D
Sbjct: 621  QPDSFQHYRSVFYSFEEEHISFALYVD 647



 Score =  568 bits (1465), Expect = e-161
 Identities = 317/528 (60%), Positives = 370/528 (70%), Gaps = 40/528 (7%)

Query: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174
            D DE  + +  E+ Q  S PR   E+   +  EV +DSL+ C  T S      DS QP++
Sbjct: 169  DDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHK 225

Query: 3175 SAFYILEQQRVGLAVD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKE 3220
                  E+ +V   +               + E E   E EE++ P  PR    L + +E
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR---NLQESEE 282

Query: 3221 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 3280
             EV Q+S D  YST S   E+    Q YSS  +SLEEQ + +A+D+ R + DQ ++EDQ 
Sbjct: 283  EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 342

Query: 3281 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 3340
               PRLSRELL+  EPEVLQDSLDRCYSTPS CLE  DSCQPY S+FY LE++ VG ++D
Sbjct: 343  ATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAID 402

Query: 3341 VGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRC 3400
            + EIEK                    +E EEDQ+P CPRLSRELLDEK PEVLQDSLDRC
Sbjct: 403  MDEIEKY-------------------QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 443

Query: 3401 YSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 3460
            YSTPS  LEL D  QPY SA Y LE+Q++GLA+ +D I+K QE EEDQ P CPRLSRELL
Sbjct: 444  YSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELL 503

Query: 3461 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGK 3520
            +  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +LDV +IEKKGKGK
Sbjct: 504  EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGK 563

Query: 3521 KRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELP 3580
            KRRGRRSKK+RRRGRKEGE+D NPPCPRL GVLMEVEE EVLQDSLDRCYSTPSMYFE P
Sbjct: 564  KRRGRRSKKKRRRGRKEGEDD-NPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQP 622

Query: 3581 DSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 3628
            DSFQHYRSVFYSFEE+HISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ
Sbjct: 623  DSFQHYRSVFYSFEEEHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ 670



 Score =  548 bits (1411), Expect = e-155
 Identities = 349/711 (49%), Positives = 420/711 (59%), Gaps = 100/711 (14%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINE LRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
           RSL EHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +SSAPRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPHK  KITFEED+V+STL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGPLSSEKAEMNILE 290
           +    SSH E +DA++I+P            GP S            P  S     + L 
Sbjct: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLS 298

Query: 291 INEKLRPQLAEKKQQFRNLKEK--CFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQF 348
           I  ++          F +L+E+  C    +         ++++++ K             
Sbjct: 299 IPPEMLASYQSYSSTFHSLEEQQVCMAVDIG--------RHRWDQVK------------- 337

Query: 349 KEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPD 408
           KE++ A   + + EL          E+E     E L++  D   S       L    +P 
Sbjct: 338 KEDQEATGPRLSREL--------LDEKE----PEVLQDSLDRCYSTPSGCLELTDSCQPY 385

Query: 409 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP---REMQKA 465
           +S    L++Q   G  +              D DE  + +  E+ Q  S P   RE+   
Sbjct: 386 RSAFYVLEQQRV-GLAI--------------DMDEIEKYQEVEEDQDPSCPRLSRELLDE 430

Query: 466 EEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVH 525
           +E EV +DSL+ C  T S+     D  QP+     + EE  +   L              
Sbjct: 431 KEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLAL-------------- 476

Query: 526 IIPENESDDEEEEEKGPVSP---RNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYS 582
            +   + D EEEE++GP  P   R L E  E EV Q+S D  YST S   E   S Q Y 
Sbjct: 477 AVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 536

Query: 583 STFHSLEEQQVCMAVDIG------------------RHRWDQVKKEDQEATGPRLSRELL 624
           S+F++LEE+ V  ++D+G                  + R  + + ED     PRL   L+
Sbjct: 537 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLM 596

Query: 625 DEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMD 675
           + + PEV QDS DRCYSTPS   E  DS Q YRS FY  E++ +  A+ +D
Sbjct: 597 EVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYVD 647


>gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
           sapiens]
          Length = 633

 Score =  823 bits (2125), Expect = 0.0
 Identities = 426/577 (73%), Positives = 477/577 (82%), Gaps = 4/577 (0%)

Query: 248 HDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR 307
           H E +D      VPGPTSSATNVSMVVSAGP S EKAEMNILEIN+K RPQLAE KQQFR
Sbjct: 37  HQELRDPT----VPGPTSSATNVSMVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFR 92

Query: 308 NLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYK 367
           NLK+KC +TQ++ FLAN+Q  Y YE+CKDLIK MLR+ER   EEKLAE+L QAEELRQYK
Sbjct: 93  NLKQKCLVTQVAYFLANRQNNYDYEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYK 152

Query: 368 VLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQ 427
           VLVH+QERELTQL+EKL+EGRDASRSLN+HLQALLTP EPD SQG+DL+EQLAEGCRLAQ
Sbjct: 153 VLVHSQERELTQLREKLQEGRDASRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQ 212

Query: 428 HLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHG 487
           HLVQKLSPEND+D+DEDV+VE AEKVQ+  APRE+QKAEEKEVPEDSLEECAIT SNSH 
Sbjct: 213 HLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHH 272

Query: 488 SYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRN 547
             +SNQP+  T+ITFEED+VDSTLI SSSH EW DAV IIPENESD E+EEEKGPVSPRN
Sbjct: 273 PCESNQPYGNTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRN 332

Query: 548 LQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQV 607
           LQESEEEE PQESWDEG  TLSIPP+M ASYQS  STFHS+EEQQV +A+DIGRH  DQV
Sbjct: 333 LQESEEEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQV 392

Query: 608 KKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQR 667
           KKEDQEAT PRLSRELLDEK PEV QDS DR YSTP   LEL D CQPYRS FY L++Q 
Sbjct: 393 KKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQH 452

Query: 668 VGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 727
           +GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR YSTP  Y ELPD 
Sbjct: 453 LGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDS 512

Query: 728 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 787
            QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+E  EPEVLQDSLD
Sbjct: 513 CQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLD 572

Query: 788 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 824
           RCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 573 RCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  453 bits (1166), Expect = e-126
 Identities = 293/605 (48%), Positives = 367/605 (60%), Gaps = 58/605 (9%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPWS EKAEMNILEIN+  RPQLAE KQQFRNLK+KC +TQ+A FLANRQ  Y Y
Sbjct: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           E+CKDLIK MLR+ER   EEKLAE+L QAEELRQYKVLVHSQERELTQLREKL+EGRDAS
Sbjct: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176

Query: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
           RSL +HLQALLTPDEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+DEDEDV+VEEAE
Sbjct: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236

Query: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV E  APREVQKAEE +VPEDSLEECAITCSNSH PC+SNQP+ N +ITFEED+V+STL
Sbjct: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           +    SSHDE  DA+ I+P      + ++       GP+S      N+ E  E+  PQ +
Sbjct: 297 I--DSSSHDEWLDAVCIIP-----ENESDHEQEEEKGPVSPR----NLQESEEEEAPQES 345

Query: 301 EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
             +  +           +S    + +  +   E +  +   L   R + ++   E  ++A
Sbjct: 346 WDEGDW----TLSIPPDMSASYQSDRSTFHSVE-EQQVGLALDIGRHWCDQVKKED-QEA 399

Query: 361 EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420
              R  + L+  +E E+      L++  D   S       L    +P +S    LQE   
Sbjct: 400 TSPRLSRELLDEKEPEV------LQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE--- 450

Query: 421 EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP---REMQKAEEKEVPEDSLEE 477
                 QHL   L  +    D E+      E+ Q    P   RE+ +  E E  +DSL+ 
Sbjct: 451 ------QHLGLALDLDRMKKDQEE------EEDQGPPCPRLSRELPEVVEPEDLQDSLDR 498

Query: 478 CAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEE 537
              T  +     DS QP+     + EE+ V  +L               + E E   E E
Sbjct: 499 WYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSL--------------DVDEIEKYQEGE 544

Query: 538 EEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVC 594
           E++ P  PR    L E+EE EV Q+S D  YST S   ++ AS+Q Y S F+S EEQ V 
Sbjct: 545 EDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVS 604

Query: 595 MAVDI 599
           +A+D+
Sbjct: 605 LALDV 609



 Score =  375 bits (962), Expect = e-103
 Identities = 226/452 (50%), Positives = 270/452 (59%), Gaps = 58/452 (12%)

Query: 3190 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3249
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 3250 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 3295
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338

Query: 3296 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3355
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 3356 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQ 3415
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 3416 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 3475
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499

Query: 3476 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGR 3535
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD+IEK                    
Sbjct: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK-------------------Y 540

Query: 3536 KEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEE 3595
            +EGEEDQ PPCPRLN VLME EE EVLQDSLDRCYST S YF+L  SFQ YRS FYSFEE
Sbjct: 541  QEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEE 600

Query: 3596 QHISFALYVDNRFFTLTVTSLHLVFQMGVIFP 3627
            Q +S AL VDNRFFTLTV   HL FQMGVIFP
Sbjct: 601  QDVSLALDVDNRFFTLTVIRHHLAFQMGVIFP 632



 Score =  369 bits (947), Expect = e-101
 Identities = 234/501 (46%), Positives = 298/501 (59%), Gaps = 46/501 (9%)

Query: 1407 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSA 1466
            +E+ +Y+ +   Q+    +L  +L + ++      SLN+        L  PD  +P +S 
Sbjct: 146  EELRQYKVLVHSQERELTQLREKLQEGRDAS---RSLNQHLQA----LLTPD--EPDNSQ 196

Query: 1467 VYSLEEQYL-GLALDVDRIKK-DQEEEEDEDQDPPCPRLS--------RELLEVVEPEVL 1516
               L EQ   G  L    ++K   E ++DED+D               RE+ +  E EV 
Sbjct: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256

Query: 1517 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 1576
            +DSL+ C  T S+     +S QPYG++    EE+ V  +L    I+     +        
Sbjct: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312

Query: 1577 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 1636
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368

Query: 1637 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 1696
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428

Query: 1697 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488

Query: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE HVGFSLDV EIEK         
Sbjct: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539

Query: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589

Query: 1877 PYRSAFYVLEQQHVGLAVDMD 1897
             YRSAFY  E+Q V LA+D+D
Sbjct: 590  QYRSAFYSFEEQDVSLALDVD 610



 Score =  365 bits (937), Expect = e-100
 Identities = 232/501 (46%), Positives = 295/501 (58%), Gaps = 48/501 (9%)

Query: 2385 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2444
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196

Query: 2445 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2492
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256

Query: 2493 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 2552
            +DSL+ C  T S+     +S QPYG++    EE+ V  +L    I+     +        
Sbjct: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312

Query: 2553 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 2612
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368

Query: 2613 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 2672
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428

Query: 2673 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2732
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488

Query: 2733 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2792
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK         
Sbjct: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539

Query: 2793 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2852
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589

Query: 2853 PYRSAFYVLEQQHVGLAVDMD 2873
             YRSAFY  E+Q V LA+D+D
Sbjct: 590  QYRSAFYSFEEQDVSLALDVD 610



 Score =  365 bits (936), Expect = e-100
 Identities = 232/501 (46%), Positives = 294/501 (58%), Gaps = 48/501 (9%)

Query: 1653 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1712
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196

Query: 1713 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 1760
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256

Query: 1761 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 1820
            +DSL+ C  T S+     +S QPYG++    EE+ V  +L    I+     +        
Sbjct: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312

Query: 1821 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 1880
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368

Query: 1881 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 1940
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428

Query: 1941 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488

Query: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE HVGFSLDV EIEK         
Sbjct: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539

Query: 2061 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2120
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589

Query: 2121 PYRSAFYVLEQQHVGLAVDMD 2141
             YRSAFY  E+Q V LA+D+D
Sbjct: 590  QYRSAFYSFEEQDVSLALDVD 610



 Score =  365 bits (936), Expect = e-100
 Identities = 232/501 (46%), Positives = 294/501 (58%), Gaps = 48/501 (9%)

Query: 1897 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1956
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196

Query: 1957 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2004
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256

Query: 2005 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 2064
            +DSL+ C  T S+     +S QPYG++    EE+ V  +L    I+     +        
Sbjct: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312

Query: 2065 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 2124
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368

Query: 2125 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 2184
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428

Query: 2185 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2244
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488

Query: 2245 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2304
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE HVGFSLDV EIEK         
Sbjct: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539

Query: 2305 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2364
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589

Query: 2365 PYRSAFYVLEQQHVGLAVDMD 2385
             YRSAFY  E+Q V LA+D+D
Sbjct: 590  QYRSAFYSFEEQDVSLALDVD 610



 Score =  365 bits (936), Expect = e-100
 Identities = 232/501 (46%), Positives = 294/501 (58%), Gaps = 48/501 (9%)

Query: 2141 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2200
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196

Query: 2201 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2248
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256

Query: 2249 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSK 2308
            +DSL+ C  T S+     +S QPYG++    EE+ V  +L    I+     +        
Sbjct: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312

Query: 2309 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 2368
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368

Query: 2369 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 2428
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428

Query: 2429 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2488
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488

Query: 2489 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2548
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE HVGFSLDV EIEK         
Sbjct: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539

Query: 2549 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2608
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589

Query: 2609 PYRSAFYVLEQQHVGLAVDMD 2629
             YRSAFY  E+Q V LA+D+D
Sbjct: 590  QYRSAFYSFEEQDVSLALDVD 610



 Score =  362 bits (929), Expect = 4e-99
 Identities = 231/501 (46%), Positives = 294/501 (58%), Gaps = 48/501 (9%)

Query: 2629 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2688
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196

Query: 2689 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2736
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256

Query: 2737 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 2796
            +DSL+ C  T S+     +S QPYG++    EE  V  +L    I+     +        
Sbjct: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312

Query: 2797 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 2856
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368

Query: 2857 AFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 2916
             F+ +E+Q VGLA+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428

Query: 2917 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2976
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488

Query: 2977 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3036
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK         
Sbjct: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539

Query: 3037 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQ 3096
                       +EGEEDQ PPCPRL+  L++ + P+VLQDSLDRCYST S   +L  S Q
Sbjct: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589

Query: 3097 PYRSAFYVLEQQRVGLAVDMD 3117
             YRSAFY  E+Q V LA+D+D
Sbjct: 590  QYRSAFYSFEEQDVSLALDVD 610



 Score =  361 bits (927), Expect = 6e-99
 Identities = 230/501 (45%), Positives = 293/501 (58%), Gaps = 48/501 (9%)

Query: 675  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 734
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196

Query: 735  VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 782
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256

Query: 783  QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 842
            +DSL+ C  T S+     +S QPYG++    EE  V  +L    I+     +        
Sbjct: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312

Query: 843  KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 902
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368

Query: 903  AFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 962
             F+ +E+Q+VG A+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428

Query: 963  SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1022
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQEEEEDQGPPCPRLSREL EVVE
Sbjct: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488

Query: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK         
Sbjct: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539

Query: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589

Query: 1143 PYRSAFYVLEQQRVGFAVDMD 1163
             YRSAFY  E+Q V  A+D+D
Sbjct: 590  QYRSAFYSFEEQDVSLALDVD 610



 Score =  360 bits (924), Expect = 1e-98
 Identities = 212/403 (52%), Positives = 257/403 (63%), Gaps = 39/403 (9%)

Query: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107
            +E E+ Q    PR   E+   +  +V +DSL+ C  T S     C+S QPY +     E+
Sbjct: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289

Query: 3108 QRV-GLAVD-------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSL 3153
             +V    +D             + E E   E EE++ P  PR  +E  +E+ P+   D  
Sbjct: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEG 349

Query: 3154 DRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSR 3213
            D   S P    ++  S Q  RS F+ +E+Q+VGLA+D+      Q  +EDQ+ + PRLSR
Sbjct: 350  DWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSR 406

Query: 3214 ELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQ 3273
            ELLDEKEPEVLQDSLDR YSTP  YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKDQ
Sbjct: 407  ELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQ 466

Query: 3274 EEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEK 3333
            EEEEDQGPPCPRLSREL EVVEPE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+
Sbjct: 467  EEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEE 526

Query: 3334 HVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVL 3393
            HVGFSLDV EIEK                    +EGEEDQ PPCPRL+  L++ + PEVL
Sbjct: 527  HVGFSLDVDEIEK-------------------YQEGEEDQKPPCPRLNEVLMEAEEPEVL 567

Query: 3394 QDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMD 3436
            QDSLDRCYST S   +L  S Q YRSAFY  E+Q V LA+D+D
Sbjct: 568  QDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610



 Score =  356 bits (913), Expect = 3e-97
 Identities = 227/501 (45%), Positives = 292/501 (58%), Gaps = 48/501 (9%)

Query: 919  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 978
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196

Query: 979  VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 1026
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256

Query: 1027 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 1086
            +DSL+ C  T S+     +S QPYG++    EE  V  +L    I+     +        
Sbjct: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312

Query: 1087 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 1146
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    +++ S Q  RS
Sbjct: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368

Query: 1147 AFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTP 1206
             F+ +E+Q+VG A+D+      Q  +EDQ+ + PRLSRELLDEKEPEVLQDSLDR YSTP
Sbjct: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428

Query: 1207 SGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVA 1266
              YLELPDL QPY S  YSL+EQ+LGLALD+DR+KKD+EEEEDQ PPCPRLSREL EVV 
Sbjct: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488

Query: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326
            PE LQDSLDR YSTP S  E PDSCQPYGS FY+LEE+HVGFSLDV EIEK         
Sbjct: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEK--------- 539

Query: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1386
                       +EGEEDQ PPCPRL+  L++ + PEVLQDSLDRCYST S   +L  S Q
Sbjct: 540  ----------YQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQ 589

Query: 1387 PYRSAFYVLEQQRVGMAVDMD 1407
             YRSAFY  E+Q V +A+D+D
Sbjct: 590  QYRSAFYSFEEQDVSLALDVD 610



 Score =  325 bits (833), Expect = 5e-88
 Identities = 209/481 (43%), Positives = 277/481 (57%), Gaps = 29/481 (6%)

Query: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932
            +E+ +Y+ +   Q+       REL   +E   LQ+  D   S       L    +P +S 
Sbjct: 146  EELRQYKVLVHSQE-------RELTQLREK--LQEGRDASRSLNQHLQALLTPDEPDNSQ 196

Query: 2933 VYSLEEQYL-GLALD---VDRIKKDQEEEEDQGPPCPRLS--------RELLEVVEPEVL 2980
               L EQ   G  L    V ++  + +++ED+                RE+ +  E EV 
Sbjct: 197  GRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAEKVQELYAPREVQKAEEKEVP 256

Query: 2981 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 3040
            +DSL+ C  T S+     +S QPYG++    EE  V  +L    I+     +        
Sbjct: 257  EDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL----IDSSSHDEWLDAVCII 312

Query: 3041 KERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRS 3100
             E     ++ EE++ P  PR  +E  +E+ P+   D  D   S P    ++  S Q  RS
Sbjct: 313  PENESDHEQ-EEEKGPVSPRNLQESEEEEAPQESWDEGDWTLSIPP---DMSASYQSDRS 368

Query: 3101 AFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTP 3160
             F+ +E+Q+VGLA+D+      Q  +EDQ+ + PRLSRELLDEK PEVLQDSLDR YSTP
Sbjct: 369  TFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTP 428

Query: 3161 SGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE 3220
               LEL D CQPYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +  E
Sbjct: 429  FEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVE 488

Query: 3221 PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQG 3280
            PE LQDSLDR YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ 
Sbjct: 489  PEDLQDSLDRWYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQK 548

Query: 3281 PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLD 3340
            PPCPRL+  L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LD
Sbjct: 549  PPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALD 608

Query: 3341 V 3341
            V
Sbjct: 609  V 609



 Score =  324 bits (831), Expect = 9e-88
 Identities = 195/410 (47%), Positives = 244/410 (59%), Gaps = 39/410 (9%)

Query: 2627 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2686
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 2687 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2732
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338

Query: 2733 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 2792
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 2793 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2852
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 2853 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2912
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499

Query: 2913 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2972
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559

Query: 2973 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3022
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  324 bits (830), Expect = 1e-87
 Identities = 195/410 (47%), Positives = 243/410 (59%), Gaps = 39/410 (9%)

Query: 2383 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2442
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 2443 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2488
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338

Query: 2489 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2548
             E  Q+S D    T S   +   S Q   S+F+++EE  VG +LD+G             
Sbjct: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 2549 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2608
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 2609 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2668
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499

Query: 2669 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2728
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559

Query: 2729 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2778
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  323 bits (829), Expect = 1e-87
 Identities = 195/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 1651 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1710
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 1711 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1756
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338

Query: 1757 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 1816
             E  Q+S D    T S   +   S Q   S+F+++EE  VG +LD+G             
Sbjct: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 1817 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1876
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 1877 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1936
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499

Query: 1937 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1996
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559

Query: 1997 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2046
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE  V  +LDV
Sbjct: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  323 bits (829), Expect = 1e-87
 Identities = 195/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 1895 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1954
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 1955 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2000
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338

Query: 2001 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2060
             E  Q+S D    T S   +   S Q   S+F+++EE  VG +LD+G             
Sbjct: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 2061 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2120
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 2121 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2180
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499

Query: 2181 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2240
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559

Query: 2241 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2290
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE  V  +LDV
Sbjct: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  323 bits (829), Expect = 1e-87
 Identities = 195/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 2199 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2244
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338

Query: 2245 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRG 2304
             E  Q+S D    T S   +   S Q   S+F+++EE  VG +LD+G             
Sbjct: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 2305 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 2364
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 2365 PYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 2424
            PYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499

Query: 2425 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 2484
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559

Query: 2485 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2534
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE  V  +LDV
Sbjct: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  323 bits (827), Expect = 2e-87
 Identities = 196/411 (47%), Positives = 244/411 (59%), Gaps = 39/411 (9%)

Query: 2871 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2930
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 2931 SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 2976
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338

Query: 2977 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 3036
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 3037 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQ 3096
                  R    +  +EDQ    PRLSRELLDEK P+VLQDSLDR YSTP   LEL D CQ
Sbjct: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 3097 PYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRC 3156
            PYRS FY L++Q +GLA+D+D ++K QE EEDQ P CPRLSREL +   PE LQDSLDR 
Sbjct: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499

Query: 3157 YSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELL 3216
            YSTP    EL DSCQPY S FY LE++ VG ++D+DEIEKYQE EEDQ P CPRL+  L+
Sbjct: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559

Query: 3217 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 3267
            + +EPEVLQDSLDRCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610



 Score =  320 bits (819), Expect = 2e-86
 Identities = 193/410 (47%), Positives = 242/410 (59%), Gaps = 39/410 (9%)

Query: 673  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 732
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 733  SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 778
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338

Query: 779  PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 838
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 839  RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 898
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 899  PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 958
            PYRS FY L++Q +G A+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499

Query: 959  YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELL 1018
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L+
Sbjct: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559

Query: 1019 EVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1068
            E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  318 bits (814), Expect = 8e-86
 Identities = 194/411 (47%), Positives = 241/411 (58%), Gaps = 39/411 (9%)

Query: 1405 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYS 1464
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL  C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 1465 SAVYSLEEQYLGLALDVDRIKKDQ-------------EEEEDEDQDPPCPRLSRELLEVV 1511
            +   + EE  +   L +D    D+             + E++E++ P  PR    L E  
Sbjct: 282  NTRITFEEDQVDSTL-IDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESE 337

Query: 1512 EPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRR 1571
            E E  Q+S D    T S   +   S Q   S+F+++EE  VG +LD+G            
Sbjct: 338  EEEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------ 385

Query: 1572 GRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSC 1631
                   R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D C
Sbjct: 386  -------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLC 438

Query: 1632 QPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDR 1691
            QPYRS FY L++QH+GLA+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR
Sbjct: 439  QPYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDR 498

Query: 1692 CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSREL 1751
             YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE EEDQ PPCPRL+  L
Sbjct: 499  WYSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVL 558

Query: 1752 LEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1802
            +E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE  V  +LDV
Sbjct: 559  MEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  317 bits (811), Expect = 2e-85
 Identities = 191/410 (46%), Positives = 241/410 (58%), Gaps = 39/410 (9%)

Query: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 977  SAVYSLEE--------------QYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVE 1022
            +   + EE              ++L     +   + D E+EE++GP  PR    L E  E
Sbjct: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPR---NLQESEE 338

Query: 1023 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1082
             E  Q+S D    T S   +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 339  EEAPQESWDEGDWTLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 1083 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1142
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 1143 PYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRC 1202
            PYRS FY L++Q +G A+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSLDR 
Sbjct: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499

Query: 1203 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELL 1262
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K +E EEDQ PPCPRL+  L+
Sbjct: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLM 559

Query: 1263 EVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1312
            E   PEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE+ V  +LDV
Sbjct: 560  EAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  312 bits (799), Expect = 4e-84
 Identities = 190/412 (46%), Positives = 241/412 (58%), Gaps = 41/412 (9%)

Query: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220
            D DE  K +E E+ Q+   PR   E+   +E EV +DSL+ C  T S      +  QPY 
Sbjct: 225  DEDEDVKVEEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYG 281

Query: 1221 SAVYSLEE--------------QYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVA 1266
            +   + EE              ++L     +   + D E+EE++ P  PR  +E  E  A
Sbjct: 282  NTRITFEEDQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEA 341

Query: 1267 PEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRG 1326
            P+   D  D   S P    +   S Q   S+F+++EE+ VG +LD+G             
Sbjct: 342  PQESWDEGDWTLSIPP---DMSASYQSDRSTFHSVEEQQVGLALDIG------------- 385

Query: 1327 RRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQ 1386
                  R    +  +EDQ    PRLSRELLDEK PEVLQDSLDR YSTP   LEL D CQ
Sbjct: 386  ------RHWCDQVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQ 439

Query: 1387 PYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRC 1446
            PYRS FY L++Q +G+A+D+D ++K QE EEDQ P CPRLSREL +  EPE LQDSL+R 
Sbjct: 440  PYRSDFYSLQEQHLGLALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRW 499

Query: 1447 YSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRE 1506
            YSTP  Y ELPD  QPY S  YSLEE+++G +LDVD I+K QE E  EDQ PPCPRL+  
Sbjct: 500  YSTPFSYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGE--EDQKPPCPRLNEV 557

Query: 1507 LLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1558
            L+E  EPEVLQDSLDRCYST S+  +   S Q Y S+FY+ EE  V  +LDV
Sbjct: 558  LMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDV 609



 Score =  309 bits (792), Expect = 3e-83
 Identities = 187/406 (46%), Positives = 237/406 (58%), Gaps = 45/406 (11%)

Query: 1094 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 1153
            +E E+ Q    PR   E+   +  EV +DSL+ C  T S      +S QPY +     E+
Sbjct: 233  EEAEKVQELYAPR---EVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEE 289

Query: 1154 QRVGFAVD--------------MDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSL 1199
             +V   +               + E E   E EE++ P  PR  +E  +E+ P+   D  
Sbjct: 290  DQVDSTLIDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEG 349

Query: 1200 DRCYSTPSGYLELPDLGQPYSS---AVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPR 1256
            D   S P      PD+   Y S     +S+EEQ +GLALD+ R   D+ ++EDQ+   PR
Sbjct: 350  DWTLSIP------PDMSASYQSDRSTFHSVEEQQVGLALDIGRHWCDQVKKEDQEATSPR 403

Query: 1257 LSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 1316
            LSRELL+   PEVLQDSLDR YSTP   LE PD CQPY S FY+L+E+H+G +LD+  ++
Sbjct: 404  LSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGLALDLDRMK 463

Query: 1317 KKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPS 1376
            K                    +E EEDQ PPCPRLSREL +   PE LQDSLDR YSTP 
Sbjct: 464  KD-------------------QEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPF 504

Query: 1377 GCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEP 1436
               EL DSCQPY S FY LE++ VG ++D+DEIEKYQE EEDQ P CPRL+  L++ +EP
Sbjct: 505  SYPELPDSCQPYGSCFYSLEEEHVGFSLDVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEP 564

Query: 1437 EVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 1482
            EVLQDSL+RCYST S Y +L    Q Y SA YS EEQ + LALDVD
Sbjct: 565  EVLQDSLDRCYSTTSTYFQLHASFQQYRSAFYSFEEQDVSLALDVD 610



 Score = 37.7 bits (86), Expect = 0.21
 Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 3/78 (3%)

Query: 169 DEDEDVQVEEAEKVLESSAPR---EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225
           D DE  + +E E+  +   PR    + +AEE +V +DSL+ C  T S       S Q ++
Sbjct: 533 DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYR 592

Query: 226 NIKITFEEDEVNSTLVVD 243
           +   +FEE +V+  L VD
Sbjct: 593 SAFYSFEEQDVSLALDVD 610


>gi|239741297 PREDICTED: neuroblastoma breakpoint family, member 9
           [Homo sapiens]
          Length = 299

 Score =  521 bits (1343), Expect = e-147
 Identities = 265/287 (92%), Positives = 273/287 (95%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKY 331
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR+LKEKCF+TQL+GFLA QQ KYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60

Query: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDAS 391
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 392 RSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 451
           RSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511
           KVQKSS+PREMQKAEEKEVPEDSLEECAIT SNSHG YDSNQPHRKTKITFEEDKVDSTL
Sbjct: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240

Query: 512 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 558
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287



 Score =  439 bits (1130), Expect = e-122
 Identities = 230/288 (79%), Positives = 247/288 (85%), Gaps = 12/288 (4%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGP SSEKAEMNILEINE LRPQLAEKKQQFR+LKEKCF+TQLAGFLA +Q KYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
           RSL EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV +SS+PRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240

Query: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGP 278
           +    SSH E +DA++I+P            GP S  T+V      GP
Sbjct: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 38.5 bits (88), Expect = 0.12
 Identities = 53/229 (23%), Positives = 92/229 (40%), Gaps = 24/229 (10%)

Query: 1389 RSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYS 1448
            R+     E++        +E+ +Y+ +   Q+    +L  +L + ++      SLN    
Sbjct: 72   RNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS---RSLNEHLQ 128

Query: 1449 TPSGYLELPDLGQPYSSAVYSLEEQYL-GLALDVDRIKK-DQEEEEDEDQDPPCPRLS-- 1504
                 L  PD  +P  S    L+EQ   G  L    ++K   E + D+D+D         
Sbjct: 129  A----LLTPD--EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKV 182

Query: 1505 ------RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1558
                  RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE+ V  +L  
Sbjct: 183  QKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIG 242

Query: 1559 GEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 1607
                 + +        ++ +      E EE++ P  PR S    ++ GP
Sbjct: 243  SSSHVEWEDAVHIIPENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 36.6 bits (83), Expect = 0.47
 Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 17/112 (15%)

Query: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174
            D DE  + +  E+ Q  S PR   E+   +  EV +DSL+ C  T S      DS QP+R
Sbjct: 169  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225

Query: 3175 SAFYILEQQRVGLAV--------------DMDEIEKYQEVEEDQDPSCPRLS 3212
                  E+ +V   +               + E E   E EE++ P  PR S
Sbjct: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 48/215 (22%), Positives = 86/215 (40%), Gaps = 32/215 (14%)

Query: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 2933 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2977
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 2978 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3037
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 3038 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPK 3072
             ++ +      E EE++ P  PR S    ++ GP+
Sbjct: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGPR 287



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 1653 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1712
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 1713 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 1757
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 1758 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGR 1817
            EV +DSL+ C  T S+     DS QP+  +    EE+ V  +L       + +       
Sbjct: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 1818 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 1851
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 1897 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1956
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 1957 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2001
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 2002 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGR 2061
            EV +DSL+ C  T S+     DS QP+  +    EE+ V  +L       + +       
Sbjct: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 2062 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 2095
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 2141 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2200
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 2201 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2245
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 2246 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGR 2305
            EV +DSL+ C  T S+     DS QP+  +    EE+ V  +L       + +       
Sbjct: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 2306 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 2339
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 2385 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2444
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 2445 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2489
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 2490 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGR 2549
            EV +DSL+ C  T S+     DS QP+  +    EE+ V  +L       + +       
Sbjct: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 2550 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 2583
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 33.5 bits (75), Expect = 3.9
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 675 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 734
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 735 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 779
              L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 780 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 839
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 198 EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 840 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 873
            ++ +      E EE++ P  PR S    ++ GP
Sbjct: 258 ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 33.5 bits (75), Expect = 3.9
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 919  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 978
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 979  VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 1023
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 1024 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 1083
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 1084 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 1117
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 33.5 bits (75), Expect = 3.9
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 2629 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2688
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 2689 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2733
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 2734 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 2793
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 2794 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 2827
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 33.5 bits (75), Expect = 3.9
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 3192 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 3251
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 3252 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 3296
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197

Query: 3297 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3356
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257

Query: 3357 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 3390
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 33.1 bits (74), Expect = 5.1
 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 14/98 (14%)

Query: 3063 RELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAV-------- 3114
            RE+   +  +V +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248

Query: 3115 ------DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGP 3146
                   + E E   E EE++ P  PR S    ++ GP
Sbjct: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 33.1 bits (74), Expect = 5.1
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 1353 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAV-------- 1404
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248

Query: 1405 ------DMDEIEKYQEVEEDQDPSCPRLS 1427
                   + E E   E EE++ P  PR S
Sbjct: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 32.7 bits (73), Expect = 6.7
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 865 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAV-------- 916
           RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248

Query: 917 ------DMDEIEKYQEVEEDQDPSCPRLS 939
                  + E E   E EE++ P  PR S
Sbjct: 249 WEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 32.7 bits (73), Expect = 6.7
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 1109 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAV-------- 1160
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248

Query: 1161 ------DMDEIEKYQEVEEDQDPSCPRLS 1183
                   + E E   E EE++ P  PR S
Sbjct: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277



 Score = 32.3 bits (72), Expect = 8.8
 Identities = 44/211 (20%), Positives = 83/211 (39%), Gaps = 26/211 (12%)

Query: 1163 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1222
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140

Query: 1223 VYSLEEQYL-GLALD---VDRIKKDEEEEEDQDPPCPRLS--------RELLEVVAPEVL 1270
               L+EQ   G  L    V ++  + + ++D+D               RE+ +    EV 
Sbjct: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVP 200

Query: 1271 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 1330
            +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++
Sbjct: 201  EDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENE 260

Query: 1331 KERRRGRKEGEEDQNPPCPRLSRELLDEKGP 1361
             +      E EE++ P  PR S    ++ GP
Sbjct: 261  SD-----DEEEEEKGPVSPRTSVGSSEKGGP 286



 Score = 32.3 bits (72), Expect = 8.8
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 3539 EEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHI 3598
            E+ Q    PR    + + EE+EV +DSL+ C  T S      DS Q +R    +FEE  +
Sbjct: 180  EKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236

Query: 3599 SFAL 3602
               L
Sbjct: 237  DSTL 240


>gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1
           [Homo sapiens]
          Length = 667

 Score =  471 bits (1213), Expect = e-132
 Identities = 280/504 (55%), Positives = 347/504 (68%), Gaps = 28/504 (5%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGF-LANQQKKYK 330
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR+LKEK  +TQ + + LANQ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDA 390
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQL+EKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 391 SRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 448
           SR LN+HL+ LLTP +PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 449 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVD 508
             EKVQ+S APRE+QK EEKEVP+DSLEECA+T SNSH   +SNQPHR TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 509 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES---WDE 563
           S L+  S H   E E+A++I PEN++D EEEE K PV PRN Q  E  E+          
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSLEPGELTNLRDFLISP 299

Query: 564 GYSTLSIP--PEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED 611
             S ++ P   +   SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D
Sbjct: 300 VVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSD 359

Query: 612 ------QEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQ 665
                 QE   PRLSR  L     E+ Q+S D C  TPS   +LT S  PY S  Y  E 
Sbjct: 360 LEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFED 419

Query: 666 QRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 725
           ++V LA+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ 
Sbjct: 420 KQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVS 478

Query: 726 DLGQPYSSAVYSLEEQYLGLALDV 749
           D  QPYSS + SLE+Q    ALDV
Sbjct: 479 DCHQPYSSTLSSLEDQLACSALDV 502



 Score =  366 bits (940), Expect = e-100
 Identities = 238/528 (45%), Positives = 309/528 (58%), Gaps = 45/528 (8%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           MVVSA P SSE+AEMNILEIN+ LR QLAE  QQFR+LKEK  +TQ   + LAN+ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 177
           SR L +HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 EAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVN 237
           E EKV ES APREVQK EE +VP+DSLEECA+TCSNSH P +SNQPH++ KITF+E EV+
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLVVDRESSHDECQDALNILP--------VPGPTSSATNVSMVVSAGPLSSEKAEMNIL 289
           S LVV+ E  HDE ++ALNI P          G           +  G L++ +  +   
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSLEPGELTNLRDFLISP 299

Query: 290 EINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQ---KKYKYEECKDLIKFMLRNER 346
            ++    P   +K   +R+ +E  FL      + + Q   + Y   +  +     L  + 
Sbjct: 300 VVSHVANPGHHDKSNSYRH-REVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQS 358

Query: 347 QFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYE 406
             +E K  E +         +V  H       ++ ++  +G   + S+   L     PY 
Sbjct: 359 DLEEVKGQETVAPRLSRGPLRVDKH-------EIPQESLDGCCLTPSILPDLTPSYHPYW 411

Query: 407 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQ 463
                 +D Q  LA        LV K+  + +  +D           Q    PR   E+ 
Sbjct: 412 STLYSFEDKQVSLA--------LVDKIKKDQEEIED-----------QSPPCPRLSQELP 452

Query: 464 KAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511
           + +E+EVPEDS+ E  +T S  H   D +QP+  T  + E+    S L
Sbjct: 453 EVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSAL 500



 Score =  151 bits (382), Expect = 1e-35
 Identities = 119/342 (34%), Positives = 177/342 (51%), Gaps = 27/342 (7%)

Query: 1480 DVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 1539
            D D  + D++EE ++ Q+ P PR   E+ +  E EV QDSL+ C  T S+     +S QP
Sbjct: 169  DEDEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQP 225

Query: 1540 YGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 1599
            + S+    +E+ V  +L V       + ++      + +     +EG+     P P  +R
Sbjct: 226  HRSTKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKA----PVPPRNR 281

Query: 1600 ELLDEKGPEVLQDSLDR---CYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM---- 1652
            + L+      L+D L      +    G  + ++S +    +F  L++Q V  A D+    
Sbjct: 282  QSLEPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDY 341

Query: 1653 -----DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYL 1700
                 DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   
Sbjct: 342  SNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILP 401

Query: 1701 ELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVL 1760
            +L     PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV 
Sbjct: 402  DLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVP 460

Query: 1761 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1802
            +DS++  Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 461  EDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  151 bits (381), Expect = 1e-35
 Identities = 120/340 (35%), Positives = 175/340 (51%), Gaps = 27/340 (7%)

Query: 748  DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 808  SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 867
            S+    +E  V  +L V       + ++      + +     +EG+     P P  +R+ 
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKA----PVPPRNRQS 283

Query: 868  LDEKGPEVLQDSLDR---CYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDM------ 918
            L+      L+D L      +    G  + ++S +    +F  L++Q+V  A D+      
Sbjct: 284  LEPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 919  ---DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 968
               DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDL 403

Query: 969  PDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 1028
                 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +D
Sbjct: 404  TPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPED 462

Query: 1029 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1068
            S++  Y TPS   +  D  QPY S+  +LE++    +LDV
Sbjct: 463  SVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  150 bits (380), Expect = 2e-35
 Identities = 120/340 (35%), Positives = 175/340 (51%), Gaps = 27/340 (7%)

Query: 2458 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2517
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2518 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2577
            S+    +E+ V  +L V       + ++      + +     +EG+     P P  +R+ 
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKA----PVPPRNRQS 283

Query: 2578 LDEKGPEVLQDSLDR---CYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM------ 2628
            L+      L+D L      +    G  + ++S +    +F  L++Q V  A D+      
Sbjct: 284  LEPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 2629 ---DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 2678
               DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDL 403

Query: 2679 PDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 2738
                 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +D
Sbjct: 404  TPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPED 462

Query: 2739 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2778
            S++  Y TPS   +  D  QPY S+  +LE++    +LDV
Sbjct: 463  SVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  150 bits (379), Expect = 2e-35
 Identities = 120/340 (35%), Positives = 174/340 (51%), Gaps = 27/340 (7%)

Query: 1726 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1785
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 1786 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1845
            S+    +E+ V  +L V       + ++      + +     +EG+     P P  +R+ 
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKA----PVPPRNRQS 283

Query: 1846 LDEKGPEVLQDSLDR---CYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM------ 1896
            L+      L+D L      +    G  + ++S +    +F  L++Q V  A D+      
Sbjct: 284  LEPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 1897 ---DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 1946
               DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDL 403

Query: 1947 PDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 2006
                 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +D
Sbjct: 404  TPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPED 462

Query: 2007 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2046
            S++  Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 463  SVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  150 bits (379), Expect = 2e-35
 Identities = 120/340 (35%), Positives = 174/340 (51%), Gaps = 27/340 (7%)

Query: 1970 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2029
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2030 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2089
            S+    +E+ V  +L V       + ++      + +     +EG+     P P  +R+ 
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKA----PVPPRNRQS 283

Query: 2090 LDEKGPEVLQDSLDR---CYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM------ 2140
            L+      L+D L      +    G  + ++S +    +F  L++Q V  A D+      
Sbjct: 284  LEPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 2141 ---DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 2190
               DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDL 403

Query: 2191 PDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 2250
                 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +D
Sbjct: 404  TPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPED 462

Query: 2251 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2290
            S++  Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 463  SVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  150 bits (379), Expect = 2e-35
 Identities = 120/340 (35%), Positives = 174/340 (51%), Gaps = 27/340 (7%)

Query: 2214 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2273
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2274 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2333
            S+    +E+ V  +L V       + ++      + +     +EG+     P P  +R+ 
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKA----PVPPRNRQS 283

Query: 2334 LDEKGPEVLQDSLDR---CYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM------ 2384
            L+      L+D L      +    G  + ++S +    +F  L++Q V  A D+      
Sbjct: 284  LEPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 2385 ---DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 2434
               DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDL 403

Query: 2435 PDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 2494
                 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +D
Sbjct: 404  TPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPED 462

Query: 2495 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2534
            S++  Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 463  SVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  150 bits (378), Expect = 3e-35
 Identities = 120/340 (35%), Positives = 174/340 (51%), Gaps = 27/340 (7%)

Query: 2702 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2761
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2762 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2821
            S+    +E  V  +L V       + ++      + +     +EG+     P P  +R+ 
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKA----PVPPRNRQS 283

Query: 2822 LDEKGPEVLQDSLDR---CYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM------ 2872
            L+      L+D L      +    G  + ++S +    +F  L++Q V  A D+      
Sbjct: 284  LEPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 2873 ---DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 2922
               DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDL 403

Query: 2923 PDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQD 2982
                 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +D
Sbjct: 404  TPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPED 462

Query: 2983 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3022
            S++  Y TPS   +  D  QPY S+  +LE++    +LDV
Sbjct: 463  SVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  149 bits (376), Expect = 5e-35
 Identities = 125/343 (36%), Positives = 171/343 (49%), Gaps = 33/343 (9%)

Query: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 1221 SAVYSLEEQYLGLALDVD----------------RIKKDEEEEEDQDPPCPRLSRELLEV 1264
            S   + +E  +  AL V+                  + D EEEE + P  PR +R+ LE 
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-NRQSLE- 285

Query: 1265 VAPEVLQDSLDRCYSTPSSCLEQP---DSCQPYGS---SFYALEEKHVGFSLDVGEIEKK 1318
              P  L +  D   S   S +  P   D    Y     SF AL+E+ V  + DV      
Sbjct: 286  --PGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 1319 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 1378
             K  +      +K+      +G+E      PRLSR  L     E+ Q+SLD C  TPS  
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSIL 400

Query: 1379 LELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEV 1438
             +LT S  PY S  Y  E ++V +A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV
Sbjct: 401  PDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEV 459

Query: 1439 LQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDV 1481
             +DS+N  Y TPS + ++ D  QPYSS + SLE+Q    ALDV
Sbjct: 460  PEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  149 bits (375), Expect = 6e-35
 Identities = 124/343 (36%), Positives = 167/343 (48%), Gaps = 33/343 (9%)

Query: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2199 SAVYSLEEQYLGLALDVD----------------RIKKDQEEEEDQGPPCPRLSRELLEV 2242
            S   + +E  +  AL V+                  + D EEEE + P  PR  + L   
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSL--- 284

Query: 2243 VEPEVLQDSLDRCYSTPSSCLEQP---DSCQPYGS---SFYALEENHVGFSLDVGEIEKK 2296
             EP  L +  D   S   S +  P   D    Y     SF AL+E  V  + DV      
Sbjct: 285  -EPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 2297 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 2356
             K  +      +K+      +G+E      PRLSR  L     E+ Q+SLD C  TPS  
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSIL 400

Query: 2357 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEV 2416
             +LT S  PY S  Y  E + V LA+ +D+I+K QE  EDQ P CPRLS+EL + KE EV
Sbjct: 401  PDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEV 459

Query: 2417 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDV 2459
             +DS++  Y TPS + ++ D  QPYSS + SLE+Q    ALDV
Sbjct: 460  PEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  148 bits (373), Expect = 1e-34
 Identities = 123/343 (35%), Positives = 168/343 (48%), Gaps = 33/343 (9%)

Query: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 977  SAVYSLEEQYLGLALDVD----------------RIKKDQEEEEDQGPPCPRLSRELLEV 1020
            S   + +E  +  AL V+                  + D EEEE + P  PR  + L   
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSL--- 284

Query: 1021 VEPEVLQDSLDRCYSTPSSCLEQP---DSCQPYGS---SFYALEEKHVGFSLDVGEIEKK 1074
             EP  L +  D   S   S +  P   D    Y     SF AL+E+ V  + DV      
Sbjct: 285  -EPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 1075 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 1134
             K  +      +K+      +G+E      PRLSR  L     E+ Q+SLD C  TPS  
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSIL 400

Query: 1135 LELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEV 1194
             +LT S  PY S  Y  E ++V  A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV
Sbjct: 401  PDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEV 459

Query: 1195 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDV 1237
             +DS++  Y TPS + ++ D  QPYSS + SLE+Q    ALDV
Sbjct: 460  PEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  147 bits (370), Expect = 2e-34
 Identities = 123/343 (35%), Positives = 167/343 (48%), Gaps = 33/343 (9%)

Query: 3190 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3249
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 3250 SAVYSLEEQYLGLALDVD----------------RIKKDQEEEEDQGPPCPRLSRELLEV 3293
            S   + +E  +  AL V+                  + D EEEE + P  PR  + L   
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSL--- 284

Query: 3294 VEPEVLQDSLDRCYSTPSSCLEQP---DSCQPYGS---SFYALEEKHVGFSLDVGEIEKK 3347
             EP  L +  D   S   S +  P   D    Y     SF AL+E+ V  + DV      
Sbjct: 285  -EPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 3348 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGC 3407
             K  +      +K+      +G+E      PRLSR  L     E+ Q+SLD C  TPS  
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSIL 400

Query: 3408 LELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEV 3467
             +L  S  PY S  Y  E + V LA+ +D+I+K QE  EDQ P CPRLS+EL + KE EV
Sbjct: 401  PDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEV 459

Query: 3468 LQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDV 3510
             +DS++  Y TPS + ++ D  QPYSS + SLE+Q    ALDV
Sbjct: 460  PEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  144 bits (364), Expect = 1e-33
 Identities = 119/342 (34%), Positives = 174/342 (50%), Gaps = 29/342 (8%)

Query: 1236 DVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295
            D D   KDEE E+ Q+ P PR   E+ +    EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1355
            S+    +E  V  +L V       + ++      + +     +EG+     P P  +R+ 
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKA----PVPPRNRQS 283

Query: 1356 LDEKGPEVLQDSLDR---CYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDM------ 1406
            L+      L+D L      +    G  + ++S +    +F  L++Q+V  A D+      
Sbjct: 284  LEPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 1407 ---DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLEL 1456
               DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SL+ C  TPS   +L
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDL 403

Query: 1457 PDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVL 1516
                 PY S +YS E++ + LAL VD+IKKDQ  EE EDQ PPCPRLS+EL EV E EV 
Sbjct: 404  TPSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQ--EEIEDQSPPCPRLSQELPEVKEQEVP 460

Query: 1517 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1558
            +DS++  Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 461  EDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  138 bits (348), Expect = 9e-32
 Identities = 116/329 (35%), Positives = 167/329 (50%), Gaps = 40/329 (12%)

Query: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107
            +E E+ Q  P PR   E+   +  +V QDSL+ C  T S      +S QP+RS     ++
Sbjct: 179  EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 3108 QRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQD 3151
              V  A+ ++                E +   E EE + P  PR +R+ L+      L+D
Sbjct: 236  HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-NRQSLEPGELTNLRD 294

Query: 3152 SLDR---CYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDM---------DE-----I 3194
             L      +    G  +  +S +    +F  L++Q+V  A D+         DE     +
Sbjct: 295  FLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFL 354

Query: 3195 EKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAV 3252
            EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L     PY S +
Sbjct: 355  EKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTL 414

Query: 3253 YSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSS 3312
            YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++  Y TPS 
Sbjct: 415  YSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 473

Query: 3313 CLEQPDSCQPYGSSFYALEEKHVGFSLDV 3341
              +  D  QPY S+  +LE++    +LDV
Sbjct: 474  HHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  129 bits (323), Expect = 7e-29
 Identities = 115/359 (32%), Positives = 171/359 (47%), Gaps = 46/359 (12%)

Query: 3265 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3324
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 3325 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3384
            S+    +E  V  +L V       + ++      + +     +EG+     P P  +R+ 
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKA----PVPPRNRQS 283

Query: 3385 LDEKGPEVLQDSLDR---CYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDM------ 3435
            L+      L+D L      +    G  +  +S +    +F  L++Q V  A D+      
Sbjct: 284  LEPGELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSN 343

Query: 3436 ---DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLEL 3485
               DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L
Sbjct: 344  PKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDL 403

Query: 3486 PDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 3545
                 PY S +YS E++ + LAL VDKI+K                    +E  EDQ+PP
Sbjct: 404  TPSYHPYWSTLYSFEDKQVSLAL-VDKIKKD-------------------QEEIEDQSPP 443

Query: 3546 CPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYV 3604
            CPRL+  L EV+E+EV +DS++  Y TPS++ ++ D  Q Y S   S E+Q    AL V
Sbjct: 444  CPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  120 bits (301), Expect = 2e-26
 Identities = 112/356 (31%), Positives = 164/356 (46%), Gaps = 59/356 (16%)

Query: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174
            D DE +K +EVE+ Q+   P   RE+   +  EV QDSL+ C  T S      +S QP+R
Sbjct: 171  DEDEDDKDEEVEKVQESPAP---REVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 3175 SAFYILEQQRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDE 3218
            S     ++  V  A+ ++                E +   E EE + P  PR +R+ L+ 
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-NRQSLEP 286

Query: 3219 KEPEVLQDSLDR---CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR------- 3268
             E   L+D L      +    G+ +  +  +    +  +L+EQ +  A DV R       
Sbjct: 287  GELTNLRDFLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 346

Query: 3269 ---------IKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS 3319
                      + D EE + Q    PRLSR  L V + E+ Q+SLD C  TPS   +   S
Sbjct: 347  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 406

Query: 3320 CQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPR 3379
              PY S+ Y+ E+K V  +L V +I+K                    +E  EDQ+PPCPR
Sbjct: 407  YHPYWSTLYSFEDKQVSLAL-VDKIKKD-------------------QEEIEDQSPPCPR 446

Query: 3380 LSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDM 3435
            LS+EL + K  EV +DS++  Y TPS   ++ D  QPY S    LE Q    A+D+
Sbjct: 447  LSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score =  115 bits (289), Expect = 6e-25
 Identities = 108/348 (31%), Positives = 160/348 (45%), Gaps = 59/348 (16%)

Query: 850  KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 909
            +E E+ Q  P PR   E+   +  EV QDSL+ C  T S     ++S QP+RS     ++
Sbjct: 179  EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 910  QRVGFAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 953
              V  A+ ++                E +   E EE + P  PR +R+ L+  E   L+D
Sbjct: 236  HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-NRQSLEPGELTNLRD 294

Query: 954  SLDR---CYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRI-------------- 996
             L      +    G+ +  +  +    +  +L+EQ +  A DV R               
Sbjct: 295  FLISPVVSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFL 354

Query: 997  --KKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 1054
              + D EE + Q    PRLSR  L V + E+ Q+SLD C  TPS   +   S  PY S+ 
Sbjct: 355  EKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTL 414

Query: 1055 YALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDE 1114
            Y+ E+K V  +L V +I+K                    +E  EDQ+PPCPRLS+EL + 
Sbjct: 415  YSFEDKQVSLAL-VDKIKKD-------------------QEEIEDQSPPCPRLSQELPEV 454

Query: 1115 KGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDM 1162
            K  EV +DS++  Y TPS   +++D  QPY S    LE Q    A+D+
Sbjct: 455  KEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 502



 Score = 41.6 bits (96), Expect = 0.014
 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 3/71 (4%)

Query: 3536 KEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEE 3595
            +E E+ Q  P PR    + + EE+EV QDSL+ C  T S      +S Q +RS   +F+E
Sbjct: 179  EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 3596 QHISFALYVDN 3606
              +  AL V++
Sbjct: 236  HEVDSALVVES 246



 Score = 40.0 bits (92), Expect = 0.042
 Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 19/126 (15%)

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDVQVEEAEKV------ 182
           P +    ++ ++  +GC L   ++  L+P            ED+ V +   +K+      
Sbjct: 377 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 436

Query: 183 LESSAP------REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEV 236
           +E  +P      +E+ + +E +VPEDS+ E  +T S  H   D +QP+ +   + E+   
Sbjct: 437 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 496

Query: 237 NSTLVV 242
            S L V
Sbjct: 497 CSALDV 502


>gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
          Length = 421

 Score =  468 bits (1204), Expect = e-131
 Identities = 246/351 (70%), Positives = 283/351 (80%), Gaps = 10/351 (2%)

Query: 259 PVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQL 318
           PVPG TSSATNV+MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFRN+K+K  +TQ+
Sbjct: 8   PVPGSTSSATNVTMVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQM 67

Query: 319 SGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELT 378
           +GFLANQQ KYKYEECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVH+QEREL 
Sbjct: 68  AGFLANQQNKYKYEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELI 127

Query: 379 QLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND 438
           QL+EKLREGRDAS SLN+HLQALLTP + D SQGQD +EQLAEGCRLA+HLV KLSPEND
Sbjct: 128 QLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPEND 187

Query: 439 NDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKT 498
            D+DE+ + +  +KVQ+S APRE QKAEEKEVPEDSLEECAITYSNSHG  DSN PH+  
Sbjct: 188 TDEDENDKTKELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNI 247

Query: 499 KITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR--------NL 548
           KIT EEDKV+S L+    SS  EW+DA++I+ EN++DDEEEE K PV P+         L
Sbjct: 248 KITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKL 307

Query: 549 QESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDI 599
           QESEE+EV Q+S +E  +T     ++  SYQ    TF +L EQ+VC A D+
Sbjct: 308 QESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDV 358



 Score =  414 bits (1063), Expect = e-114
 Identities = 212/258 (82%), Positives = 227/258 (87%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60
           MVVSAGPWSSEKAEMNILEINE LRPQLAE KQQFRN+K+K  +TQ+AGFLAN+Q KYKY
Sbjct: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80

Query: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLR E QFKEEKLAEQLKQAEELRQYKVLVHSQEREL QLREKLREGRDAS
Sbjct: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140

Query: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
            SL +HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND DEDE+ + +E +
Sbjct: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200

Query: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240
           KV ES APRE QKAEE +VPEDSLEECAIT SNSHGP DSN PHKNIKIT EED+VNS L
Sbjct: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260

Query: 241 VVDRESSHDECQDALNIL 258
           VVD ESS DE QDALNIL
Sbjct: 261 VVDSESSQDEWQDALNIL 278



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%)

Query: 2602 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2661
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 2662 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2705
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 2706 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2760
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 2761 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 2789
              +F AL E+ V  + DV       KG++
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 58/209 (27%), Positives = 93/209 (44%), Gaps = 27/209 (12%)

Query: 2846 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2905
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 2906 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2949
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 2950 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3004
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 3005 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3033
              +F AL E+ V  + DV       KG++
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 62.8 bits (151), Expect = 6e-09
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 892  ELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 951
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 952  QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 995
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 996  IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1050
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 1051 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1079
              +F AL E+ V  + DV       KG++
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 62.8 bits (151), Expect = 6e-09
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 1626 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1685
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 1686 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1729
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 1730 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1784
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 1785 GSSFYALEENHVGFSLDVGEIEKKGKGKK 1813
              +F AL E  V  + DV       KG++
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 62.8 bits (151), Expect = 6e-09
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 1870 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1929
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 1930 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1973
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 1974 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2028
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 2029 GSSFYALEENHVGFSLDVGEIEKKGKGKK 2057
              +F AL E  V  + DV       KG++
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 62.8 bits (151), Expect = 6e-09
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 2114 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2173
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 2174 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2217
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 2218 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2272
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 2273 GSSFYALEENHVGFSLDVGEIEKKGKGKK 2301
              +F AL E  V  + DV       KG++
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 62.8 bits (151), Expect = 6e-09
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 2358 ELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 2417
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 2418 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 2461
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 2462 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 2516
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 2517 GSSFYALEENHVGFSLDVGEIEKKGKGKK 2545
              +F AL E  V  + DV       KG++
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 62.4 bits (150), Expect = 8e-09
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 3165 ELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3224
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 3225 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 3268
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 3269 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 3323
             + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 3324 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 3352
              +F AL E+ V  + DV       KG++
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 58/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 648 ELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 707
           +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167 QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 708 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 751
           +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221 EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 752 IKKDQEEEEDQGPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 806
            + D EEEE + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281 NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 807 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 835
             +F AL E+ V  + DV       KG++
Sbjct: 341 EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 61.2 bits (147), Expect = 2e-08
 Identities = 56/209 (26%), Positives = 92/209 (44%), Gaps = 25/209 (11%)

Query: 1380 ELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1439
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 1440 QDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDR--------------IK 1485
            +DSL  C  T S      D   P+ +   + EE  +   L VD               ++
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 1486 KDQEEEEDEDQDPPCPRLSR-----ELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1540
               ++EE+E + P  P+++      +L E  E EVLQDS +   +T  S  +   S QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 1541 GSSFYALEENHVGFSLDVGEIEKKGKGKK 1569
              +F AL E  V  + DV       KG++
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 60.5 bits (145), Expect = 3e-08
 Identities = 57/209 (27%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 1136 ELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 1195
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 1196 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD----------------R 1239
            +DSL+ C  T S      D   P+ +   + EE  +   L VD                 
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 1240 IKKDEEEEEDQDPPCPRLSR-----ELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPY 1294
             + D+EEEE + P  P+++      +L E    EVLQDS +   +T  S  +   S QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 1295 GSSFYALEEKHVGFSLDVGEIEKKGKGKK 1323
              +F AL E+ V  + DV       KG++
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 53.5 bits (127), Expect = 4e-06
 Identities = 59/220 (26%), Positives = 96/220 (43%), Gaps = 25/220 (11%)

Query: 1480 DVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 1539
            D D  + D+ +E D+ Q+ P PR   E  +  E EV +DSL+ C  T S+     DS  P
Sbjct: 187  DTDEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPP 243

Query: 1540 YGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 1599
            + +     EE+ V   L V   + +    + +   +     +   E EE + P  P+++ 
Sbjct: 244  HKNIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300

Query: 1600 -----ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDE 1654
                 +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+  
Sbjct: 301  WICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVAS 360

Query: 1655 IEKYQEVEED-----------QDPSCPRLSRE---LLDEK 1680
                 + EE            +D    R+S++   LLDEK
Sbjct: 361  EHSNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 53.1 bits (126), Expect = 5e-06
 Identities = 49/195 (25%), Positives = 87/195 (44%), Gaps = 8/195 (4%)

Query: 3409 ELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVL 3468
            +L + C+  R   + L  ++     D DE +K +E+++ Q+   PR  ++    +E EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPREEQKA---EEKEVP 220

Query: 3469 QDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSK 3528
            +DSL+ C  T S      D   P+ +   + EE  +   L VD    + + +       +
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 3529 KERRRGRKEGEEDQNPPCPR-LNGV-LMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHY 3586
             +     +EG+    P     + G+ L E EE+EVLQDS +   +T     ++  S+Q  
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 3587 RSVFYSFEEQHISFA 3601
               F +  EQ +  A
Sbjct: 341  EGTFLALVEQKVCSA 355



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 55/209 (26%), Positives = 92/209 (44%), Gaps = 27/209 (12%)

Query: 3090 ELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVL 3149
            +L + C+  R   + L  +      D DE +K +E+++ Q+   PR   +  +EK  EV 
Sbjct: 167  QLAEGCRLARHLVHKLSPEN---DTDEDENDKTKELDKVQESPAPR-EEQKAEEK--EVP 220

Query: 3150 QDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVG--LAVDMD--------------E 3193
            +DSL+ C  T S      DS  P+++     E+ +V   L VD +              E
Sbjct: 221  EDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLE 280

Query: 3194 IEKYQEVEEDQDPSCPRLS-----RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPY 3248
             +   E EE + P  P+++      +L + +E EVLQDS +   +T     ++    QP 
Sbjct: 281  NQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPC 340

Query: 3249 SSAVYSLEEQYLGLALDVDRIKKDQEEEE 3277
                 +L EQ +  A DV     + + EE
Sbjct: 341  EGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 49.3 bits (116), Expect = 7e-05
 Identities = 57/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 1236 DVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295
            D D   K +E ++ Q+ P PR  ++  E   PE   DSL+ C  T S+     DS  P+ 
Sbjct: 189  DEDENDKTKELDKVQESPAPREEQKAEEKEVPE---DSLEECAITYSNSHGPSDSNPPHK 245

Query: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1353
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302

Query: 1354 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIE 1410
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362

Query: 1411 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1434
               + EE            +D    R+S++   LLDEK
Sbjct: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 748 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807
           D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 189 DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245

Query: 808 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 865
           +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 246 NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302

Query: 866 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIE 922
              +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 303 CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362

Query: 923 KYQEVEED-----------QDPSCPRLSRE---LLDEK 946
              + EE            +D    R+S++   LLDEK
Sbjct: 363 SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 992  DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1051
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245

Query: 1052 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1109
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302

Query: 1110 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIE 1166
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q+V  A D+    
Sbjct: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362

Query: 1167 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1190
               + EE            +D    R+S++   LLDEK
Sbjct: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 1726 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1785
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245

Query: 1786 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 1843
            +     EE+ V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302

Query: 1844 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 1900
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+    
Sbjct: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362

Query: 1901 KYQEVEED-----------QDPSCPRLSRE---LLDEK 1924
               + EE            +D    R+S++   LLDEK
Sbjct: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 1970 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2029
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245

Query: 2030 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2087
            +     EE+ V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302

Query: 2088 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2144
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+    
Sbjct: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362

Query: 2145 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2168
               + EE            +D    R+S++   LLDEK
Sbjct: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 2214 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2273
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245

Query: 2274 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2331
            +     EE+ V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302

Query: 2332 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2388
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+    
Sbjct: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362

Query: 2389 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2412
               + EE            +D    R+S++   LLDEK
Sbjct: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 58/218 (26%), Positives = 93/218 (42%), Gaps = 25/218 (11%)

Query: 2458 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2517
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245

Query: 2518 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2575
            +     EE+ V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302

Query: 2576 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2632
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+    
Sbjct: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362

Query: 2633 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2656
               + EE            +D    R+S++   LLDEK
Sbjct: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 58/218 (26%), Positives = 92/218 (42%), Gaps = 25/218 (11%)

Query: 2702 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2761
            D D   K +E ++ Q  P PR   E  +  E EV +DSL+ C  T S+     DS  P+ 
Sbjct: 189  DEDENDKTKELDKVQESPAPR---EEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHK 245

Query: 2762 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR-- 2819
            +     EE  V   L V   + +    + +   +     +   E EE + P  P+++   
Sbjct: 246  NIKITSEEDKVNSILVV---DSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWI 302

Query: 2820 ---ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE 2876
               +L + +  EVLQDS +   +T     +++ S QP    F  L +Q V  A D+    
Sbjct: 303  CGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEH 362

Query: 2877 KYQEVEED-----------QDPSCPRLSRE---LLDEK 2900
               + EE            +D    R+S++   LLDEK
Sbjct: 363  SNSKGEETPLGFPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 46.2 bits (108), Expect = 6e-04
 Identities = 54/207 (26%), Positives = 89/207 (42%), Gaps = 38/207 (18%)

Query: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107
            KE ++ Q  P PR  ++  +++ P   +DSL+ C  T S      DS  P+++     E+
Sbjct: 197  KELDKVQESPAPREEQKAEEKEVP---EDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253

Query: 3108 QRVG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLSR-----ELLDEKGP 3146
             +V   L VD +              E +   E EE + P  P+++      +L + +  
Sbjct: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313

Query: 3147 EVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEED--- 3203
            EVLQDS +   +T     ++  S QP    F  L +Q+V  A D+       + EE    
Sbjct: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLG 373

Query: 3204 --------QDPSCPRLSRE---LLDEK 3219
                    +D    R+S++   LLDEK
Sbjct: 374  FPDTKYCWKDEKDERMSQKVAFLLDEK 400



 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 24/176 (13%)

Query: 3367 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3426
            KE ++ Q  P PR  ++  +++ PE   DSL+ C  T S      DS  P+++     E+
Sbjct: 197  KELDKVQESPAPREEQKAEEKEVPE---DSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253

Query: 3427 QHVG--LAVDMD--------------EIEKYQEVEEDQDPSCPRLSR-----ELLDEKEP 3465
              V   L VD +              E +   E EE + P  P+++      +L + +E 
Sbjct: 254  DKVNSILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEK 313

Query: 3466 EVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKK 3521
            EVLQDS +   +T     ++    QP      +L EQ +  A DV       KG++
Sbjct: 314  EVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEE 369



 Score = 35.4 bits (80), Expect = 1.0
 Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 3536 KEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEE 3595
            KE ++ Q  P PR      + EE+EV +DSL+ C  T S      DS   ++++  + EE
Sbjct: 197  KELDKVQESPAPREE---QKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEE 253

Query: 3596 QHISFALYVDN 3606
              ++  L VD+
Sbjct: 254  DKVNSILVVDS 264


>gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2
           [Homo sapiens]
          Length = 638

 Score =  468 bits (1203), Expect = e-131
 Identities = 275/499 (55%), Positives = 340/499 (68%), Gaps = 47/499 (9%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGF-LANQQKKYK 330
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR+LKEK  +TQ + + LANQ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDA 390
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQL+EKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 391 SRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 448
           SR LN+HL+ LLTP +PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 449 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVD 508
             EKVQ+S APRE+QK EEKEVP+DSLEECA+T SNSH   +SNQPHR TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 509 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 566
           S L+  S H   E E+A++I PEN++D EEEE K PV PR+  +S               
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285

Query: 567 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 611
                     SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D     
Sbjct: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 612 -QEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGL 670
            QE   PRLSR  L     E+ Q+S D C  TPS   +LT S  PY S  Y  E ++V L
Sbjct: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395

Query: 671 AIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 730
           A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ D  QP
Sbjct: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454

Query: 731 YSSAVYSLEEQYLGLALDV 749
           YSS + SLE+Q    ALDV
Sbjct: 455 YSSTLSSLEDQLACSALDV 473



 Score =  363 bits (932), Expect = 2e-99
 Identities = 236/520 (45%), Positives = 304/520 (58%), Gaps = 58/520 (11%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           MVVSA P SSE+AEMNILEIN+ LR QLAE  QQFR+LKEK  +TQ   + LAN+ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 177
           SR L +HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 EAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVN 237
           E EKV ES APREVQK EE +VP+DSLEECA+TCSNSH P +SNQPH++ KITF+E EV+
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRP 297
           S LVV+ E  HDE ++ALNI P                       + +    E    + P
Sbjct: 240 SALVVESEHPHDEEEEALNIPP---------------------ENQNDHEEEEGKAPVPP 278

Query: 298 QLAEKKQQFRNLKEKCFLTQLSGFLANQQ---KKYKYEECKDLIKFMLRNERQFKEEKLA 354
           +  +K   +R+ +E  FL      + + Q   + Y   +  +     L  +   +E K  
Sbjct: 279 RHHDKSNSYRH-REVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQ 337

Query: 355 EQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQD 414
           E +         +V  H       ++ ++  +G   + S+   L     PY       +D
Sbjct: 338 ETVAPRLSRGPLRVDKH-------EIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFED 390

Query: 415 LQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVP 471
            Q  LA        LV K+  + +  +D           Q    PR   E+ + +E+EVP
Sbjct: 391 KQVSLA--------LVDKIKKDQEEIED-----------QSPPCPRLSQELPEVKEQEVP 431

Query: 472 EDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511
           EDS+ E  +T S  H   D +QP+  T  + E+    S L
Sbjct: 432 EDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSAL 471



 Score =  150 bits (378), Expect = 3e-35
 Identities = 119/322 (36%), Positives = 164/322 (50%), Gaps = 20/322 (6%)

Query: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 1221 SAVYSLEEQYLGLALDVD-RIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYS 1279
            S   + +E  +  AL V+     DEEEE    PP  +   E  E  AP            
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275

Query: 1280 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1339
             P    ++ +S +    SF AL+E+ V  + DV       K  +      +K+      +
Sbjct: 276  VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 1340 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 1399
            G+E      PRLSR  L     E+ Q+SLD C  TPS   +LT S  PY S  Y  E ++
Sbjct: 336  GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392

Query: 1400 VGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDL 1459
            V +A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS+N  Y TPS + ++ D 
Sbjct: 393  VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451

Query: 1460 GQPYSSAVYSLEEQYLGLALDV 1481
             QPYSS + SLE+Q    ALDV
Sbjct: 452  HQPYSSTLSSLEDQLACSALDV 473



 Score =  146 bits (368), Expect = 4e-34
 Identities = 119/339 (35%), Positives = 169/339 (49%), Gaps = 50/339 (14%)

Query: 1480 DVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 1539
            D D  + D++EE ++ Q+ P PR   E+ +  E EV QDSL+ C  T S+     +S QP
Sbjct: 169  DEDEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQP 225

Query: 1540 YGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 1599
            + S+    +E+ V  +L V                   E      E EE  N P P    
Sbjct: 226  HRSTKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQN 265

Query: 1600 ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM------- 1652
            +  +E+G   +          P    + ++S +    +F  L++Q V  A D+       
Sbjct: 266  DHEEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNP 315

Query: 1653 --DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1703
              DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L 
Sbjct: 316  KWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLT 375

Query: 1704 DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS 1763
                PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS
Sbjct: 376  PSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDS 434

Query: 1764 LDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1802
            ++  Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 435  VNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  146 bits (368), Expect = 4e-34
 Identities = 116/323 (35%), Positives = 164/323 (50%), Gaps = 22/323 (6%)

Query: 748  DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 808  SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 867
            S+    +E  V  +L V   E +    +     +     +   E EE + P  PR   + 
Sbjct: 228  STKITFKEHEVDSALVV---ESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKS 284

Query: 868  LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEV 927
               +  EV   +LD             D  + Y +  +  ++  +GF      +EK  ++
Sbjct: 285  NSYRHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGF------LEKQSDL 331

Query: 928  EE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 985
            EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L     PY S +YS E++
Sbjct: 332  EEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDK 391

Query: 986  YLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 1045
             + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++  Y TPS   +  D
Sbjct: 392  QVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSD 450

Query: 1046 SCQPYGSSFYALEEKHVGFSLDV 1068
              QPY S+  +LE++    +LDV
Sbjct: 451  CHQPYSSTLSSLEDQLACSALDV 473



 Score =  145 bits (366), Expect = 7e-34
 Identities = 120/337 (35%), Positives = 167/337 (49%), Gaps = 50/337 (14%)

Query: 2458 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2517
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2518 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2577
            S+    +E+ V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 2578 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2628
             +E+G   +          P    + ++S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 2629 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2681
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 2682 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2741
              PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 2742 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2778
              Y TPS   +  D  QPY S+  +LE++    +LDV
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  145 bits (365), Expect = 9e-34
 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%)

Query: 1726 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1785
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 1786 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1845
            S+    +E+ V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 1846 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 1896
             +E+G   +          P    + ++S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 1897 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1949
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 1950 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2009
              PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 2010 RCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2046
              Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  145 bits (365), Expect = 9e-34
 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%)

Query: 1970 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2029
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2030 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2089
            S+    +E+ V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 2090 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2140
             +E+G   +          P    + ++S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 2141 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2193
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 2194 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2253
              PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 2254 RCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2290
              Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  145 bits (365), Expect = 9e-34
 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%)

Query: 2214 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2273
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2274 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2333
            S+    +E+ V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 2334 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2384
             +E+G   +          P    + ++S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 2385 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2437
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 2438 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2497
              PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 2498 RCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2534
              Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  144 bits (364), Expect = 1e-33
 Identities = 117/322 (36%), Positives = 160/322 (49%), Gaps = 20/322 (6%)

Query: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2199 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 2257
            S   + +E  +  AL V+      EEEE    PP  +   E  E   P            
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275

Query: 2258 TPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 2317
             P    ++ +S +    SF AL+E  V  + DV       K  +      +K+      +
Sbjct: 276  VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 2318 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQH 2377
            G+E      PRLSR  L     E+ Q+SLD C  TPS   +LT S  PY S  Y  E + 
Sbjct: 336  GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392

Query: 2378 VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2437
            V LA+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ D 
Sbjct: 393  VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451

Query: 2438 GQPYSSAVYSLEEQYLGLALDV 2459
             QPYSS + SLE+Q    ALDV
Sbjct: 452  HQPYSSTLSSLEDQLACSALDV 473



 Score =  144 bits (364), Expect = 1e-33
 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%)

Query: 2702 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2761
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2762 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2821
            S+    +E  V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 2822 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2872
             +E+G   +          P    + ++S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 2873 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2925
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 2926 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2985
              PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 2986 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3022
              Y TPS   +  D  QPY S+  +LE++    +LDV
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  144 bits (362), Expect = 2e-33
 Identities = 116/322 (36%), Positives = 161/322 (50%), Gaps = 20/322 (6%)

Query: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 977  SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 1035
            S   + +E  +  AL V+      EEEE    PP  +   E  E   P            
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275

Query: 1036 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1095
             P    ++ +S +    SF AL+E+ V  + DV       K  +      +K+      +
Sbjct: 276  VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 1096 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 1155
            G+E      PRLSR  L     E+ Q+SLD C  TPS   +LT S  PY S  Y  E ++
Sbjct: 336  GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392

Query: 1156 VGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1215
            V  A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ D 
Sbjct: 393  VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451

Query: 1216 GQPYSSAVYSLEEQYLGLALDV 1237
             QPYSS + SLE+Q    ALDV
Sbjct: 452  HQPYSSTLSSLEDQLACSALDV 473



 Score =  142 bits (359), Expect = 5e-33
 Identities = 116/322 (36%), Positives = 160/322 (49%), Gaps = 20/322 (6%)

Query: 3190 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3249
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 3250 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 3308
            S   + +E  +  AL V+      EEEE    PP  +   E  E   P            
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275

Query: 3309 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 3368
             P    ++ +S +    SF AL+E+ V  + DV       K  +      +K+      +
Sbjct: 276  VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 3369 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQH 3428
            G+E      PRLSR  L     E+ Q+SLD C  TPS   +L  S  PY S  Y  E + 
Sbjct: 336  GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392

Query: 3429 VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3488
            V LA+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ D 
Sbjct: 393  VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451

Query: 3489 GQPYSSAVYSLEEQYLGLALDV 3510
             QPYSS + SLE+Q    ALDV
Sbjct: 452  HQPYSSTLSSLEDQLACSALDV 473



 Score =  139 bits (350), Expect = 5e-32
 Identities = 119/339 (35%), Positives = 166/339 (48%), Gaps = 52/339 (15%)

Query: 1236 DVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295
            D D   KDEE E+ Q+ P PR   E+ +    EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1355
            S+    +E  V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 1356 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDM--------- 1406
             +E+G   +          P    + ++S +    +F  L++Q+V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 1407 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDL 1459
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SL+ C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 1460 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDS 1519
              PY S +YS E++ + LAL VD+IKKDQ  EE EDQ PPCPRLS+EL EV E EV +DS
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQ--EEIEDQSPPCPRLSQELPEVKEQEVPEDS 434

Query: 1520 LDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1558
            ++  Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 435  VNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  139 bits (350), Expect = 5e-32
 Identities = 110/310 (35%), Positives = 160/310 (51%), Gaps = 31/310 (10%)

Query: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107
            +E E+ Q  P PR   E+   +  +V QDSL+ C  T S      +S QP+RS     ++
Sbjct: 179  EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 3108 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELC 3167
              V  A+ ++    + E EE  +   P    +  +E+G   +          P    +  
Sbjct: 236  HEVDSALVVESEHPHDEEEEALNIP-PENQNDHEEEEGKAPV----------PPRHHDKS 284

Query: 3168 DSCQPYRSAFYILEQQRVGLAVDM---------DE-----IEKYQEVEE--DQDPSCPRL 3211
            +S +    +F  L++Q+V  A D+         DE     +EK  ++EE   Q+   PRL
Sbjct: 285  NSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRL 344

Query: 3212 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 3271
            SR  L   + E+ Q+SLD C  TPS   +L     PY S +YS E++ + LAL VD+IKK
Sbjct: 345  SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403

Query: 3272 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 3331
            DQEE EDQ PPCPRLS+EL EV E EV +DS++  Y TPS   +  D  QPY S+  +LE
Sbjct: 404  DQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLE 463

Query: 3332 EKHVGFSLDV 3341
            ++    +LDV
Sbjct: 464  DQLACSALDV 473



 Score =  123 bits (309), Expect = 3e-27
 Identities = 115/356 (32%), Positives = 163/356 (45%), Gaps = 69/356 (19%)

Query: 3265 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3324
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 3325 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3384
            S+    +E  V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 3385 LDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDM--------- 3435
             +E+G   +          P    +  +S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 3436 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3488
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 3489 GQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPR 3548
              PY S +YS E++ + LAL VDKI+K                    +E  EDQ+PPCPR
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKD-------------------QEEIEDQSPPCPR 417

Query: 3549 LNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYV 3604
            L+  L EV+E+EV +DS++  Y TPS++ ++ D  Q Y S   S E+Q    AL V
Sbjct: 418  LSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  120 bits (302), Expect = 2e-26
 Identities = 108/337 (32%), Positives = 155/337 (45%), Gaps = 50/337 (14%)

Query: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174
            D DE +K +EVE+ Q+   P   RE+   +  EV QDSL+ C  T S      +S QP+R
Sbjct: 171  DEDEDDKDEEVEKVQESPAP---REVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 3175 SAFYILEQQRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDE 3218
            S     ++  V  A+ ++                E +   E EE + P  PR   +    
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSY 287

Query: 3219 KEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEED 3278
            +  EV   +LD             D+ + YS+  +  +E  LG        + D EE + 
Sbjct: 288  RHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKG 336

Query: 3279 QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFS 3338
            Q    PRLSR  L V + E+ Q+SLD C  TPS   +   S  PY S+ Y+ E+K V  +
Sbjct: 337  QETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLA 396

Query: 3339 LDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLD 3398
            L V +I+K                    +E  EDQ+PPCPRLS+EL + K  EV +DS++
Sbjct: 397  L-VDKIKKD-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 3399 RCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDM 3435
              Y TPS   ++ D  QPY S    LE Q    A+D+
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  116 bits (290), Expect = 5e-25
 Identities = 104/329 (31%), Positives = 151/329 (45%), Gaps = 50/329 (15%)

Query: 850  KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 909
            +E E+ Q  P PR   E+   +  EV QDSL+ C  T S     ++S QP+RS     ++
Sbjct: 179  EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 910  QRVGFAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 953
              V  A+ ++                E +   E EE + P  PR   +    +  EV   
Sbjct: 236  HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFL 295

Query: 954  SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRL 1013
            +LD             D+ + YS+  +  +E  LG        + D EE + Q    PRL
Sbjct: 296  ALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPRL 344

Query: 1014 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK 1073
            SR  L V + E+ Q+SLD C  TPS   +   S  PY S+ Y+ E+K V  +L V +I+K
Sbjct: 345  SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403

Query: 1074 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSG 1133
                                +E  EDQ+PPCPRLS+EL + K  EV +DS++  Y TPS 
Sbjct: 404  D-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444

Query: 1134 CLELTDSCQPYRSAFYVLEQQRVGFAVDM 1162
              +++D  QPY S    LE Q    A+D+
Sbjct: 445  HHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score = 41.6 bits (96), Expect = 0.014
 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 3/71 (4%)

Query: 3536 KEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEE 3595
            +E E+ Q  P PR    + + EE+EV QDSL+ C  T S      +S Q +RS   +F+E
Sbjct: 179  EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 3596 QHISFALYVDN 3606
              +  AL V++
Sbjct: 236  HEVDSALVVES 246



 Score = 40.0 bits (92), Expect = 0.042
 Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 19/126 (15%)

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDVQVEEAEKV------ 182
           P +    ++ ++  +GC L   ++  L+P            ED+ V +   +K+      
Sbjct: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407

Query: 183 LESSAP------REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEV 236
           +E  +P      +E+ + +E +VPEDS+ E  +T S  H   D +QP+ +   + E+   
Sbjct: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 467

Query: 237 NSTLVV 242
            S L V
Sbjct: 468 CSALDV 473


>gi|221218991 neuroblastoma breakpoint family, member 4 [Homo
           sapiens]
          Length = 638

 Score =  468 bits (1203), Expect = e-131
 Identities = 275/499 (55%), Positives = 340/499 (68%), Gaps = 47/499 (9%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGF-LANQQKKYK 330
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR+LKEK  +TQ + + LANQ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDA 390
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVH+Q +ELTQL+EKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 391 SRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 448
           SR LN+HL+ LLTP +PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 449 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVD 508
             EKVQ+S APRE+QK EEKEVP+DSLEECA+T SNSH   +SNQPHR TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 509 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 566
           S L+  S H   E E+A++I PEN++D EEEE K PV PR+  +S               
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285

Query: 567 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 611
                     SY+    +F +L+EQ+VC A D+ R     +WD+       K+ D     
Sbjct: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 612 -QEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGL 670
            QE   PRLSR  L     E+ Q+S D C  TPS   +LT S  PY S  Y  E ++V L
Sbjct: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395

Query: 671 AIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 730
           A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ D  QP
Sbjct: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454

Query: 731 YSSAVYSLEEQYLGLALDV 749
           YSS + SLE+Q    ALDV
Sbjct: 455 YSSTLSSLEDQLACSALDV 473



 Score =  363 bits (932), Expect = 2e-99
 Identities = 236/520 (45%), Positives = 304/520 (58%), Gaps = 58/520 (11%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           MVVSA P SSE+AEMNILEIN+ LR QLAE  QQFR+LKEK  +TQ   + LAN+ KKYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EE KD+I  +LR+E Q   EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 177
           SR L +HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 EAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVN 237
           E EKV ES APREVQK EE +VP+DSLEECA+TCSNSH P +SNQPH++ KITF+E EV+
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRP 297
           S LVV+ E  HDE ++ALNI P                       + +    E    + P
Sbjct: 240 SALVVESEHPHDEEEEALNIPP---------------------ENQNDHEEEEGKAPVPP 278

Query: 298 QLAEKKQQFRNLKEKCFLTQLSGFLANQQ---KKYKYEECKDLIKFMLRNERQFKEEKLA 354
           +  +K   +R+ +E  FL      + + Q   + Y   +  +     L  +   +E K  
Sbjct: 279 RHHDKSNSYRH-REVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQ 337

Query: 355 EQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQD 414
           E +         +V  H       ++ ++  +G   + S+   L     PY       +D
Sbjct: 338 ETVAPRLSRGPLRVDKH-------EIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFED 390

Query: 415 LQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVP 471
            Q  LA        LV K+  + +  +D           Q    PR   E+ + +E+EVP
Sbjct: 391 KQVSLA--------LVDKIKKDQEEIED-----------QSPPCPRLSQELPEVKEQEVP 431

Query: 472 EDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511
           EDS+ E  +T S  H   D +QP+  T  + E+    S L
Sbjct: 432 EDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSAL 471



 Score =  150 bits (378), Expect = 3e-35
 Identities = 119/322 (36%), Positives = 164/322 (50%), Gaps = 20/322 (6%)

Query: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 1221 SAVYSLEEQYLGLALDVD-RIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYS 1279
            S   + +E  +  AL V+     DEEEE    PP  +   E  E  AP            
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275

Query: 1280 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1339
             P    ++ +S +    SF AL+E+ V  + DV       K  +      +K+      +
Sbjct: 276  VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 1340 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 1399
            G+E      PRLSR  L     E+ Q+SLD C  TPS   +LT S  PY S  Y  E ++
Sbjct: 336  GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392

Query: 1400 VGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDL 1459
            V +A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS+N  Y TPS + ++ D 
Sbjct: 393  VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451

Query: 1460 GQPYSSAVYSLEEQYLGLALDV 1481
             QPYSS + SLE+Q    ALDV
Sbjct: 452  HQPYSSTLSSLEDQLACSALDV 473



 Score =  146 bits (368), Expect = 4e-34
 Identities = 119/339 (35%), Positives = 169/339 (49%), Gaps = 50/339 (14%)

Query: 1480 DVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 1539
            D D  + D++EE ++ Q+ P PR   E+ +  E EV QDSL+ C  T S+     +S QP
Sbjct: 169  DEDEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQP 225

Query: 1540 YGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 1599
            + S+    +E+ V  +L V                   E      E EE  N P P    
Sbjct: 226  HRSTKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQN 265

Query: 1600 ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM------- 1652
            +  +E+G   +          P    + ++S +    +F  L++Q V  A D+       
Sbjct: 266  DHEEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNP 315

Query: 1653 --DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1703
              DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L 
Sbjct: 316  KWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLT 375

Query: 1704 DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS 1763
                PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS
Sbjct: 376  PSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDS 434

Query: 1764 LDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1802
            ++  Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 435  VNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  146 bits (368), Expect = 4e-34
 Identities = 116/323 (35%), Positives = 164/323 (50%), Gaps = 22/323 (6%)

Query: 748  DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 808  SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 867
            S+    +E  V  +L V   E +    +     +     +   E EE + P  PR   + 
Sbjct: 228  STKITFKEHEVDSALVV---ESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKS 284

Query: 868  LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEV 927
               +  EV   +LD             D  + Y +  +  ++  +GF      +EK  ++
Sbjct: 285  NSYRHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGF------LEKQSDL 331

Query: 928  EE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 985
            EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L     PY S +YS E++
Sbjct: 332  EEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDK 391

Query: 986  YLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 1045
             + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++  Y TPS   +  D
Sbjct: 392  QVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSD 450

Query: 1046 SCQPYGSSFYALEEKHVGFSLDV 1068
              QPY S+  +LE++    +LDV
Sbjct: 451  CHQPYSSTLSSLEDQLACSALDV 473



 Score =  145 bits (366), Expect = 7e-34
 Identities = 120/337 (35%), Positives = 167/337 (49%), Gaps = 50/337 (14%)

Query: 2458 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2517
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2518 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2577
            S+    +E+ V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 2578 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2628
             +E+G   +          P    + ++S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 2629 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2681
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 2682 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2741
              PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 2742 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2778
              Y TPS   +  D  QPY S+  +LE++    +LDV
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  145 bits (365), Expect = 9e-34
 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%)

Query: 1726 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1785
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 1786 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1845
            S+    +E+ V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 1846 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 1896
             +E+G   +          P    + ++S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 1897 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1949
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 1950 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2009
              PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 2010 RCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2046
              Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  145 bits (365), Expect = 9e-34
 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%)

Query: 1970 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2029
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2030 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2089
            S+    +E+ V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 2090 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2140
             +E+G   +          P    + ++S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 2141 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2193
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 2194 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2253
              PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 2254 RCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2290
              Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  145 bits (365), Expect = 9e-34
 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%)

Query: 2214 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2273
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2274 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2333
            S+    +E+ V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 2334 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2384
             +E+G   +          P    + ++S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 2385 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2437
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 2438 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2497
              PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 2498 RCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2534
              Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  144 bits (364), Expect = 1e-33
 Identities = 117/322 (36%), Positives = 160/322 (49%), Gaps = 20/322 (6%)

Query: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2199 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 2257
            S   + +E  +  AL V+      EEEE    PP  +   E  E   P            
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275

Query: 2258 TPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 2317
             P    ++ +S +    SF AL+E  V  + DV       K  +      +K+      +
Sbjct: 276  VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 2318 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQH 2377
            G+E      PRLSR  L     E+ Q+SLD C  TPS   +LT S  PY S  Y  E + 
Sbjct: 336  GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392

Query: 2378 VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2437
            V LA+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ D 
Sbjct: 393  VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451

Query: 2438 GQPYSSAVYSLEEQYLGLALDV 2459
             QPYSS + SLE+Q    ALDV
Sbjct: 452  HQPYSSTLSSLEDQLACSALDV 473



 Score =  144 bits (364), Expect = 1e-33
 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%)

Query: 2702 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2761
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 2762 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2821
            S+    +E  V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 2822 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2872
             +E+G   +          P    + ++S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 2873 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2925
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 2926 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2985
              PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 2986 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3022
              Y TPS   +  D  QPY S+  +LE++    +LDV
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  144 bits (362), Expect = 2e-33
 Identities = 116/322 (36%), Positives = 161/322 (50%), Gaps = 20/322 (6%)

Query: 917  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 977  SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 1035
            S   + +E  +  AL V+      EEEE    PP  +   E  E   P            
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275

Query: 1036 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1095
             P    ++ +S +    SF AL+E+ V  + DV       K  +      +K+      +
Sbjct: 276  VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 1096 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 1155
            G+E      PRLSR  L     E+ Q+SLD C  TPS   +LT S  PY S  Y  E ++
Sbjct: 336  GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392

Query: 1156 VGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1215
            V  A+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ D 
Sbjct: 393  VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451

Query: 1216 GQPYSSAVYSLEEQYLGLALDV 1237
             QPYSS + SLE+Q    ALDV
Sbjct: 452  HQPYSSTLSSLEDQLACSALDV 473



 Score =  142 bits (359), Expect = 5e-33
 Identities = 116/322 (36%), Positives = 160/322 (49%), Gaps = 20/322 (6%)

Query: 3190 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3249
            D DE +K +EVE+ Q+   PR   E+   +E EV QDSL+ C  T S      +  QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 3250 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 3308
            S   + +E  +  AL V+      EEEE    PP  +   E  E   P            
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275

Query: 3309 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 3368
             P    ++ +S +    SF AL+E+ V  + DV       K  +      +K+      +
Sbjct: 276  VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335

Query: 3369 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQH 3428
            G+E      PRLSR  L     E+ Q+SLD C  TPS   +L  S  PY S  Y  E + 
Sbjct: 336  GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392

Query: 3429 VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3488
            V LA+ +D+I+K QE  EDQ P CPRLS+EL + KE EV +DS++  Y TPS + ++ D 
Sbjct: 393  VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451

Query: 3489 GQPYSSAVYSLEEQYLGLALDV 3510
             QPYSS + SLE+Q    ALDV
Sbjct: 452  HQPYSSTLSSLEDQLACSALDV 473



 Score =  139 bits (350), Expect = 5e-32
 Identities = 119/339 (35%), Positives = 166/339 (48%), Gaps = 52/339 (15%)

Query: 1236 DVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295
            D D   KDEE E+ Q+ P PR   E+ +    EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1355
            S+    +E  V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 1356 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDM--------- 1406
             +E+G   +          P    + ++S +    +F  L++Q+V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 1407 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDL 1459
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SL+ C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 1460 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDS 1519
              PY S +YS E++ + LAL VD+IKKDQ  EE EDQ PPCPRLS+EL EV E EV +DS
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKDQ--EEIEDQSPPCPRLSQELPEVKEQEVPEDS 434

Query: 1520 LDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1558
            ++  Y TPS   +  D  QPY S+  +LE+     +LDV
Sbjct: 435  VNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  139 bits (350), Expect = 5e-32
 Identities = 110/310 (35%), Positives = 160/310 (51%), Gaps = 31/310 (10%)

Query: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107
            +E E+ Q  P PR   E+   +  +V QDSL+ C  T S      +S QP+RS     ++
Sbjct: 179  EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 3108 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELC 3167
              V  A+ ++    + E EE  +   P    +  +E+G   +          P    +  
Sbjct: 236  HEVDSALVVESEHPHDEEEEALNIP-PENQNDHEEEEGKAPV----------PPRHHDKS 284

Query: 3168 DSCQPYRSAFYILEQQRVGLAVDM---------DE-----IEKYQEVEE--DQDPSCPRL 3211
            +S +    +F  L++Q+V  A D+         DE     +EK  ++EE   Q+   PRL
Sbjct: 285  NSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRL 344

Query: 3212 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 3271
            SR  L   + E+ Q+SLD C  TPS   +L     PY S +YS E++ + LAL VD+IKK
Sbjct: 345  SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403

Query: 3272 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 3331
            DQEE EDQ PPCPRLS+EL EV E EV +DS++  Y TPS   +  D  QPY S+  +LE
Sbjct: 404  DQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLE 463

Query: 3332 EKHVGFSLDV 3341
            ++    +LDV
Sbjct: 464  DQLACSALDV 473



 Score =  123 bits (309), Expect = 3e-27
 Identities = 115/356 (32%), Positives = 163/356 (45%), Gaps = 69/356 (19%)

Query: 3265 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3324
            D D   KD+E E+ Q  P PR   E+ +  E EV QDSL+ C  T S+     +S QP+ 
Sbjct: 171  DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 3325 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3384
            S+    +E  V  +L V                   E      E EE  N P P    + 
Sbjct: 228  STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267

Query: 3385 LDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDM--------- 3435
             +E+G   +          P    +  +S +    +F  L++Q V  A D+         
Sbjct: 268  EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317

Query: 3436 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3488
            DE     +EK  ++EE   Q+   PRLSR  L   + E+ Q+SLD C  TPS   +L   
Sbjct: 318  DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377

Query: 3489 GQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPR 3548
              PY S +YS E++ + LAL VDKI+K                    +E  EDQ+PPCPR
Sbjct: 378  YHPYWSTLYSFEDKQVSLAL-VDKIKKD-------------------QEEIEDQSPPCPR 417

Query: 3549 LNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYV 3604
            L+  L EV+E+EV +DS++  Y TPS++ ++ D  Q Y S   S E+Q    AL V
Sbjct: 418  LSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  120 bits (302), Expect = 2e-26
 Identities = 108/337 (32%), Positives = 155/337 (45%), Gaps = 50/337 (14%)

Query: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174
            D DE +K +EVE+ Q+   P   RE+   +  EV QDSL+ C  T S      +S QP+R
Sbjct: 171  DEDEDDKDEEVEKVQESPAP---REVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227

Query: 3175 SAFYILEQQRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDE 3218
            S     ++  V  A+ ++                E +   E EE + P  PR   +    
Sbjct: 228  STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSY 287

Query: 3219 KEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEED 3278
            +  EV   +LD             D+ + YS+  +  +E  LG        + D EE + 
Sbjct: 288  RHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKG 336

Query: 3279 QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFS 3338
            Q    PRLSR  L V + E+ Q+SLD C  TPS   +   S  PY S+ Y+ E+K V  +
Sbjct: 337  QETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLA 396

Query: 3339 LDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLD 3398
            L V +I+K                    +E  EDQ+PPCPRLS+EL + K  EV +DS++
Sbjct: 397  L-VDKIKKD-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436

Query: 3399 RCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDM 3435
              Y TPS   ++ D  QPY S    LE Q    A+D+
Sbjct: 437  EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score =  116 bits (290), Expect = 5e-25
 Identities = 104/329 (31%), Positives = 151/329 (45%), Gaps = 50/329 (15%)

Query: 850  KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 909
            +E E+ Q  P PR   E+   +  EV QDSL+ C  T S     ++S QP+RS     ++
Sbjct: 179  EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 910  QRVGFAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 953
              V  A+ ++                E +   E EE + P  PR   +    +  EV   
Sbjct: 236  HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFL 295

Query: 954  SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRL 1013
            +LD             D+ + YS+  +  +E  LG        + D EE + Q    PRL
Sbjct: 296  ALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPRL 344

Query: 1014 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK 1073
            SR  L V + E+ Q+SLD C  TPS   +   S  PY S+ Y+ E+K V  +L V +I+K
Sbjct: 345  SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403

Query: 1074 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSG 1133
                                +E  EDQ+PPCPRLS+EL + K  EV +DS++  Y TPS 
Sbjct: 404  D-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444

Query: 1134 CLELTDSCQPYRSAFYVLEQQRVGFAVDM 1162
              +++D  QPY S    LE Q    A+D+
Sbjct: 445  HHDVSDCHQPYSSTLSSLEDQLACSALDV 473



 Score = 41.6 bits (96), Expect = 0.014
 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 3/71 (4%)

Query: 3536 KEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEE 3595
            +E E+ Q  P PR    + + EE+EV QDSL+ C  T S      +S Q +RS   +F+E
Sbjct: 179  EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235

Query: 3596 QHISFALYVDN 3606
              +  AL V++
Sbjct: 236  HEVDSALVVES 246



 Score = 40.0 bits (92), Expect = 0.042
 Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 19/126 (15%)

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDVQVEEAEKV------ 182
           P +    ++ ++  +GC L   ++  L+P            ED+ V +   +K+      
Sbjct: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407

Query: 183 LESSAP------REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEV 236
           +E  +P      +E+ + +E +VPEDS+ E  +T S  H   D +QP+ +   + E+   
Sbjct: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 467

Query: 237 NSTLVV 242
            S L V
Sbjct: 468 CSALDV 473


>gi|239758011 PREDICTED: hypothetical protein LOC728841, partial [Homo
            sapiens]
          Length = 166

 Score =  225 bits (573), Expect = 7e-58
 Identities = 109/123 (88%), Positives = 115/123 (93%)

Query: 2751 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 2810
            LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2811 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV 2870
            NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2871 DMD 2873
            D+D
Sbjct: 121  DVD 123



 Score =  224 bits (571), Expect = 1e-57
 Identities = 109/123 (88%), Positives = 115/123 (93%)

Query: 3314 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 3373
            LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 3374 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAV 3433
            NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 3434 DMD 3436
            D+D
Sbjct: 121  DVD 123



 Score =  223 bits (568), Expect = 3e-57
 Identities = 108/123 (87%), Positives = 114/123 (92%)

Query: 1531 LEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 1590
            LEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1591 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV 1650
            NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1651 DMD 1653
            D+D
Sbjct: 121  DVD 123



 Score =  223 bits (568), Expect = 3e-57
 Identities = 108/123 (87%), Positives = 114/123 (92%)

Query: 1775 LEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 1834
            LEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1835 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV 1894
            NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1895 DMD 1897
            D+D
Sbjct: 121  DVD 123



 Score =  223 bits (568), Expect = 3e-57
 Identities = 108/123 (87%), Positives = 114/123 (92%)

Query: 2019 LEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 2078
            LEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2079 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV 2138
            NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2139 DMD 2141
            D+D
Sbjct: 121  DVD 123



 Score =  223 bits (568), Expect = 3e-57
 Identities = 108/123 (87%), Positives = 114/123 (92%)

Query: 2263 LEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 2322
            LEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2323 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV 2382
            NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2383 DMD 2385
            D+D
Sbjct: 121  DVD 123



 Score =  223 bits (568), Expect = 3e-57
 Identities = 108/123 (87%), Positives = 114/123 (92%)

Query: 2507 LEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 2566
            LEQPDSCQPYGSSFYALEE HVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2567 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV 2626
            NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q++GLA+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2627 DMD 2629
            D+D
Sbjct: 121  DVD 123



 Score =  223 bits (567), Expect = 4e-57
 Identities = 108/123 (87%), Positives = 114/123 (92%)

Query: 1285 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 1344
            LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1345 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAV 1404
            NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +G+A+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1405 DMD 1407
            D+D
Sbjct: 121  DVD 123



 Score =  222 bits (565), Expect = 6e-57
 Identities = 108/123 (87%), Positives = 113/123 (91%)

Query: 797 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 856
           LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 857 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAV 916
           NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +G A+
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 917 DMD 919
           D+D
Sbjct: 121 DVD 123



 Score =  222 bits (565), Expect = 6e-57
 Identities = 108/123 (87%), Positives = 113/123 (91%)

Query: 1041 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 1100
            LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1101 NPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAV 1160
            NPPCPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +G A+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1161 DMD 1163
            D+D
Sbjct: 121  DVD 123



 Score =  221 bits (563), Expect = 1e-56
 Identities = 108/123 (87%), Positives = 114/123 (92%)

Query: 2995 LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 3054
            LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 3055 NPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAV 3114
            NPPCPRLSRELLDEK P+VLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 3115 DMD 3117
            D+D
Sbjct: 121  DVD 123



 Score =  202 bits (513), Expect = 6e-51
 Identities = 99/144 (68%), Positives = 117/144 (81%)

Query: 3483 LELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ 3542
            LE PD  QPY S+ Y+LEE+++G +LDV +IEKKGKGKKRRGRRSKK+RRRGRKEGEEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 3543 NPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFAL 3602
            NPPCPRL+  L++ +E EVLQDSLDRCYSTPS Y ELPD  Q Y S  YS EEQ++  AL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 3603 YVDNRFFTLTVTSLHLVFQMGVIF 3626
             VD+ + T+ V SLHLVFQ+GVIF
Sbjct: 121  DVDSEYLTMKVISLHLVFQIGVIF 144



 Score =  169 bits (429), Expect = 4e-41
 Identities = 87/123 (70%), Positives = 95/123 (77%), Gaps = 19/123 (15%)

Query: 1625 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQ 1665
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1666 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 1725
            +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1726 DVD 1728
            DVD
Sbjct: 121  DVD 123



 Score =  169 bits (429), Expect = 4e-41
 Identities = 87/123 (70%), Positives = 95/123 (77%), Gaps = 19/123 (15%)

Query: 1869 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQ 1909
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1910 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 1969
            +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1970 DVD 1972
            DVD
Sbjct: 121  DVD 123



 Score =  169 bits (429), Expect = 4e-41
 Identities = 87/123 (70%), Positives = 95/123 (77%), Gaps = 19/123 (15%)

Query: 2113 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQ 2153
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2154 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2213
            +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2214 DVD 2216
            DVD
Sbjct: 121  DVD 123



 Score =  169 bits (429), Expect = 4e-41
 Identities = 87/123 (70%), Positives = 95/123 (77%), Gaps = 19/123 (15%)

Query: 2357 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQ 2397
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2398 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2457
            +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2458 DVD 2460
            DVD
Sbjct: 121  DVD 123



 Score =  169 bits (429), Expect = 4e-41
 Identities = 87/123 (70%), Positives = 95/123 (77%), Gaps = 19/123 (15%)

Query: 2601 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQ 2641
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2642 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2701
            +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2702 DVD 2704
            DVD
Sbjct: 121  DVD 123



 Score =  169 bits (429), Expect = 4e-41
 Identities = 87/123 (70%), Positives = 95/123 (77%), Gaps = 19/123 (15%)

Query: 2845 LELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQ 2885
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2886 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 2945
            +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2946 DVD 2948
            DVD
Sbjct: 121  DVD 123



 Score =  169 bits (427), Expect = 6e-41
 Identities = 87/123 (70%), Positives = 95/123 (77%), Gaps = 19/123 (15%)

Query: 891 LELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKY-------------------QEVEEDQ 931
           LE  DSCQPY S+FY LE++ VGF++D+ EIEK                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 932 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 991
           +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 992 DVD 994
           DVD
Sbjct: 121 DVD 123



 Score =  169 bits (427), Expect = 6e-41
 Identities = 87/123 (70%), Positives = 95/123 (77%), Gaps = 19/123 (15%)

Query: 1135 LELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKY-------------------QEVEEDQ 1175
            LE  DSCQPY S+FY LE++ VGF++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1176 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 1235
            +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1236 DVD 1238
            DVD
Sbjct: 121  DVD 123



 Score =  169 bits (427), Expect = 6e-41
 Identities = 87/123 (70%), Positives = 95/123 (77%), Gaps = 19/123 (15%)

Query: 3408 LELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKY-------------------QEVEEDQ 3448
            LE  DSCQPY S+FY LE++HVG ++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 3449 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 3508
            +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 3509 DVD 3511
            DVD
Sbjct: 121  DVD 123



 Score =  166 bits (421), Expect = 3e-40
 Identities = 86/123 (69%), Positives = 94/123 (76%), Gaps = 19/123 (15%)

Query: 647 LELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKY-------------------QEVEEDQ 687
           LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 688 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 747
           +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 748 DVD 750
           DVD
Sbjct: 121 DVD 123



 Score =  165 bits (418), Expect = 7e-40
 Identities = 86/123 (69%), Positives = 94/123 (76%), Gaps = 19/123 (15%)

Query: 3164 LELCDSCQPYRSAFYILEQQRVGLAVDMDEIEKY-------------------QEVEEDQ 3204
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 3205 DPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 3264
            +P CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 3265 DVD 3267
            DVD
Sbjct: 121  DVD 123



 Score =  164 bits (416), Expect = 1e-39
 Identities = 85/123 (69%), Positives = 94/123 (76%), Gaps = 19/123 (15%)

Query: 1379 LELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKY-------------------QEVEEDQ 1419
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1420 DPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 1479
            +P CPRLSRELLDEKEPEVLQDSL+RCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1480 DVD 1482
            DVD
Sbjct: 121  DVD 123



 Score =  135 bits (341), Expect = 6e-31
 Identities = 73/123 (59%), Positives = 85/123 (69%), Gaps = 19/123 (15%)

Query: 3089 LELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKY-------------------QEVEEDQ 3129
            LE  DSCQPY S+FY LE++ VG ++D+ EIEK                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 3130 DPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYILEQQRVGLAV 3189
            +P CPRLSRELLDEK PEVLQDSLDRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 3190 DMD 3192
            D+D
Sbjct: 121  DVD 123



 Score =  128 bits (321), Expect = 1e-28
 Identities = 67/122 (54%), Positives = 82/122 (67%), Gaps = 19/122 (15%)

Query: 722 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 762
           LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1   LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 763 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 822
            PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +L
Sbjct: 61  NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 823 DV 824
           DV
Sbjct: 121 DV 122



 Score =  128 bits (321), Expect = 1e-28
 Identities = 67/122 (54%), Positives = 82/122 (67%), Gaps = 19/122 (15%)

Query: 966  LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 1006
            LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1007 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 1066
             PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +L
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1067 DV 1068
            DV
Sbjct: 121  DV 122



 Score =  128 bits (321), Expect = 1e-28
 Identities = 67/122 (54%), Positives = 82/122 (67%), Gaps = 19/122 (15%)

Query: 2676 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 2716
            LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2717 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 2776
             PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +L
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2777 DV 2778
            DV
Sbjct: 121  DV 122



 Score =  128 bits (321), Expect = 1e-28
 Identities = 67/122 (54%), Positives = 82/122 (67%), Gaps = 19/122 (15%)

Query: 2920 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 2960
            LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2961 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 3020
             PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +L
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 3021 DV 3022
            DV
Sbjct: 121  DV 122



 Score =  128 bits (321), Expect = 1e-28
 Identities = 67/122 (54%), Positives = 82/122 (67%), Gaps = 19/122 (15%)

Query: 3239 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 3279
            LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 3280 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 3339
             PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +L
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 3340 DV 3341
            DV
Sbjct: 121  DV 122



 Score =  127 bits (320), Expect = 2e-28
 Identities = 67/122 (54%), Positives = 81/122 (66%), Gaps = 19/122 (15%)

Query: 1700 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 1740
            LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1741 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSL 1800
             PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +L
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1801 DV 1802
            DV
Sbjct: 121  DV 122



 Score =  127 bits (320), Expect = 2e-28
 Identities = 67/122 (54%), Positives = 81/122 (66%), Gaps = 19/122 (15%)

Query: 1944 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 1984
            LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1985 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSL 2044
             PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +L
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2045 DV 2046
            DV
Sbjct: 121  DV 122



 Score =  127 bits (320), Expect = 2e-28
 Identities = 67/122 (54%), Positives = 81/122 (66%), Gaps = 19/122 (15%)

Query: 2188 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 2228
            LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2229 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSL 2288
             PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +L
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2289 DV 2290
            DV
Sbjct: 121  DV 122



 Score =  127 bits (320), Expect = 2e-28
 Identities = 67/122 (54%), Positives = 81/122 (66%), Gaps = 19/122 (15%)

Query: 2432 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------QEEEEDQ 2472
            LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 2473 GPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSL 2532
             PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +L
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 2533 DV 2534
            DV
Sbjct: 121  DV 122



 Score =  127 bits (319), Expect = 2e-28
 Identities = 66/122 (54%), Positives = 83/122 (68%), Gaps = 17/122 (13%)

Query: 1454 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQE-----------------EEEDEDQ 1496
            LE PD  QPY S+ Y+LEE+++G +LDV  I+K  +                 +E +EDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1497 DPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSL 1556
            +PPCPRLSRELL+  EPEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE ++G +L
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1557 DV 1558
            DV
Sbjct: 121  DV 122



 Score =  126 bits (316), Expect = 4e-28
 Identities = 66/122 (54%), Positives = 82/122 (67%), Gaps = 19/122 (15%)

Query: 1210 LELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKD-------------------EEEEEDQ 1250
            LE PD  QPY S+ Y+LEE+++G +LDV  I+K                    +E EEDQ
Sbjct: 1    LEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQ 60

Query: 1251 DPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 1310
            +PPCPRLSRELL+   PEVLQDSLDRCYSTPS  LE PD  QPY S+ Y+LEE+++G +L
Sbjct: 61   NPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120

Query: 1311 DV 1312
            DV
Sbjct: 121  DV 122



 Score =  106 bits (264), Expect = 5e-22
 Identities = 60/118 (50%), Positives = 73/118 (61%), Gaps = 19/118 (16%)

Query: 577 SYQSYSSTFHSLEEQQVCMAVDIG-------------------RHRWDQVKKEDQEATGP 617
           S Q Y S+F++LEE+ V  ++D+G                   R R  +  +EDQ    P
Sbjct: 6   SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCP 65

Query: 618 RLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMD 675
           RLSRELLDEK PEV QDS DRCYSTPSG LEL D  QPY SA Y LE+Q +GLA+D+D
Sbjct: 66  RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 123



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 29/68 (42%), Positives = 40/68 (58%), Gaps = 3/68 (4%)

Query: 535 EEEEEKGPVSPR---NLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQ 591
           E EE++ P  PR    L + +E EV Q+S D  YST S   E+    Q YSS  +SLEEQ
Sbjct: 55  EGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 114

Query: 592 QVCMAVDI 599
            + +A+D+
Sbjct: 115 YLGLALDV 122


>gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  116 bits (290), Expect = 5e-25
 Identities = 74/190 (38%), Positives = 110/190 (57%), Gaps = 9/190 (4%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGF-LANQQKKYK 330
           M VSA      +AEM+ILE N+ LR +L + KQ F++L EK   ++ + + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDA 390
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT L++K++EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120

Query: 391 SRSLNEHL-------QALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDD 442
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 443 EDVQVEVAEK 452
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190



 Score =  112 bits (280), Expect = 7e-24
 Identities = 72/184 (39%), Positives = 107/184 (58%), Gaps = 9/184 (4%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           M VSA      +AEM+ILE N+ LR +L + KQ F++L EK   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ +Q  ELT LR+K++EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120

Query: 120 SRSLYEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEN-DEDED 171
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN +  ++
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQ 175
           ED Q
Sbjct: 181 EDRQ 184


>gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  113 bits (283), Expect = 3e-24
 Identities = 73/190 (38%), Positives = 109/190 (57%), Gaps = 9/190 (4%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGF-LANQQKKYK 330
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++ + + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDA 390
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT L++K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 391 SRSLNEHL-------QALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDD 442
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 443 EDVQVEVAEK 452
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190



 Score =  109 bits (273), Expect = 4e-23
 Identities = 71/184 (38%), Positives = 106/184 (57%), Gaps = 9/184 (4%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ +Q  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLYEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEN-DEDED 171
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN +  ++
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQ 175
           ED Q
Sbjct: 181 EDRQ 184


>gi|239741281 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 322

 Score =  113 bits (283), Expect = 3e-24
 Identities = 73/190 (38%), Positives = 109/190 (57%), Gaps = 9/190 (4%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGF-LANQQKKYK 330
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++ + + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDA 390
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT L++K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 391 SRSLNEHL-------QALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDD 442
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 443 EDVQVEVAEK 452
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190



 Score =  109 bits (273), Expect = 4e-23
 Identities = 71/184 (38%), Positives = 106/184 (57%), Gaps = 9/184 (4%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ +Q  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLYEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEN-DEDED 171
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN +  ++
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQ 175
           ED Q
Sbjct: 181 EDRQ 184


>gi|239752894 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 298

 Score =  112 bits (279), Expect = 9e-24
 Identities = 72/190 (37%), Positives = 108/190 (56%), Gaps = 9/190 (4%)

Query: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGF-LANQQKKYK 330
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++ + + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDA 390
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ AQ  ELT L++K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 391 SRSLNEHLQALLTPYEP-------DKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDD 442
                +H++  +  +E           Q Q   EQ+ +G +L + LV+KL  EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180

Query: 443 EDVQVEVAEK 452
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190



 Score =  107 bits (266), Expect = 3e-22
 Identities = 71/184 (38%), Positives = 104/184 (56%), Gaps = 9/184 (4%)

Query: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F++L EK   ++   + L N  +KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EECKDLI+ +L  E QF+E +LAE  + A  LR +  L+ +Q  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLYEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEN-DEDED 171
                +H+       + LL        Q Q   EQ+ +G +L + LV+KL  EN +  ++
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180

Query: 172 EDVQ 175
           ED Q
Sbjct: 181 EDRQ 184


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score = 83.6 bits (205), Expect = 3e-15
 Identities = 69/222 (31%), Positives = 112/222 (50%), Gaps = 20/222 (9%)

Query: 79   EEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEH-------LQALL 131
            EEKLAE+L+ A    +Y  L+  Q REL+ LR+K+REGR     +  H        + LL
Sbjct: 1458 EEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLL 1517

Query: 132  TPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREV 191
              ++ D   GQ  +EQLA+G +L + L  KLS ++ + E +   +E     L     RE+
Sbjct: 1518 RSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEP----LALRLSREL 1573

Query: 192  QKAEE-SKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDE 250
            Q+ E+  +V +  L+  ++T S+SH   DS++   +     +E E  S + +  E +H E
Sbjct: 1574 QEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHYE 1633

Query: 251  CQDALNILPVPGPTSSATNVSMVVSAGPLSSE-----KAEMN 287
             + A    P    +   ++ S V+S+ P S+      KAE N
Sbjct: 1634 EKKA---SPSHSDSIHHSSHSAVLSSKPSSTSASQGAKAESN 1672



 Score = 76.3 bits (186), Expect = 5e-13
 Identities = 56/182 (30%), Positives = 95/182 (52%), Gaps = 14/182 (7%)

Query: 350  EEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEH-------LQALL 402
            EEKLAE+L+ A    +Y  L+  Q REL+ L++K+REGR     +  H        + LL
Sbjct: 1458 EEKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLL 1517

Query: 403  TPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVE-VAEKVQKSSAPRE 461
               + D   GQ  +EQLA+G +L + L  KLS ++   + +   +E +A ++      RE
Sbjct: 1518 RSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSEKDQAGLEPLALRLS-----RE 1572

Query: 462  MQKAEEK-EVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 520
            +Q+ E+  EV +  L+  ++T S+SH   DS++    T    +E +  S +   S +  +
Sbjct: 1573 LQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHY 1632

Query: 521  ED 522
            E+
Sbjct: 1633 EE 1634



 Score = 49.3 bits (116), Expect = 7e-05
 Identities = 159/739 (21%), Positives = 270/739 (36%), Gaps = 161/739 (21%)

Query: 84   EQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQD 143
            E L    E  Q+       E EL +L+ ++ E   +S S   +    L        +  +
Sbjct: 1005 EMLHLRAEFHQHLEEKRKAEEELKELKAQIEEAGFSSVSHIRNTMLSLC------LENAE 1058

Query: 144  LQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEA---EKVLESSAPREVQKAEESKVP 200
            L+EQ+ E       +      E D+++ E V VE     E + ESS   E +K +     
Sbjct: 1059 LKEQMGEAMSDGWEI------EEDKEKGE-VMVETVVTKEGLSESSLQAEFRKLQGKLKN 1111

Query: 201  EDSL-----EECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDAL 255
              ++     E+  ++    +       P   + +T   + +N+ LV        + +  +
Sbjct: 1112 AHNIINLLKEQLVLSSKEGNSKLT---PELLVHLTSTIERINTELVGSPGKHQHQEEGNV 1168

Query: 256  NILPVPGPTSSATNVSMVVSAGPLSSE--------KAEMNILEINEKLRPQLAEKKQQFR 307
             + P P P S     +  V A  L ++        ++  ++    + LR QL++ KQ+++
Sbjct: 1169 TVRPFPRPQSLDLGATFTVDAHQLDNQSQPRDPGPQSAFSLPGSTQHLRSQLSQCKQRYQ 1228

Query: 308  NLKEKCFLTQLSGFL-ANQQKKYKYEECKDLIKFMLRNERQFKEEKL------------- 353
            +L+EK  L++ + F  AN+ +KY         + ML  E   K++               
Sbjct: 1229 DLQEKLLLSEATVFAQANELEKY---------RVMLTGESLVKQDSKQIQVDLQDLGYET 1279

Query: 354  ---AEQLKQAEELRQYKVLVHAQERELTQLK----EKLREGRD-ASRSLNEHLQALLTPY 405
               +E   + EE    +   H   +E+  ++    E+ R G   AS S  + L+  L   
Sbjct: 1280 CGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLENQLGKQ 1339

Query: 406  EPDKSQGQ------------DLQEQLAEGCRLAQHL---VQKLSPENDNDDDEDVQVEVA 450
            E  +  G+            DL+ QL    ++ Q+L   V+ LS  +D            
Sbjct: 1340 EEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSS-------L 1392

Query: 451  EKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDST 510
            E+  K  A   ++ +    VP++         S+  G++ S  P  + K   E      +
Sbjct: 1393 ERPWKLRAVGTLEGSSPHSVPDEDEG----WLSDGTGAFYS--PGLQAKKDLE------S 1440

Query: 511  LIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSI 570
            LI   S +E +     +P+N                 L+E   EE+   SW   Y +L  
Sbjct: 1441 LIQRVSQLEAQ-----LPKN----------------GLEEKLAEELRSASWPGKYDSLIQ 1479

Query: 571  PPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPE 630
                  SY          E + +C  +   RH  D VK  +       +   L      +
Sbjct: 1480 DQARELSYLRQKIR----EGRGICYLIT--RHAKDTVKSFEDLLRSNDIDYYLGQSFREQ 1533

Query: 631  VFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQ--- 687
            + Q SQ            LT+      S                    K  + E+DQ   
Sbjct: 1534 LAQGSQ------------LTERLTSKLST-------------------KDHKSEKDQAGL 1562

Query: 688  DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLA 746
            +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS  +  +E  L   
Sbjct: 1563 EPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEAC 1620

Query: 747  LDVDRIKKDQEEEEDQGPP 765
             D+D + +    EE +  P
Sbjct: 1621 SDMDIVSEYTHYEEKKASP 1639



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 81/359 (22%), Positives = 143/359 (39%), Gaps = 52/359 (14%)

Query: 80  EKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKS 139
           E LA++ K+ EEL Q    + +QER + QL               E  Q L   +EP   
Sbjct: 166 EALAQRDKRIEELNQS---LAAQERLVEQLSR-------------EKQQLLHLLEEPTSM 209

Query: 140 QGQDLQEQLAEGCRLAQHLV----QKLSPENDEDEDEDVQVEEA-EKVLESSAPR---EV 191
           + Q + E+L +  +L  H      Q +S  +  +  E +Q  EA  K+L+        E+
Sbjct: 210 EVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYEL 269

Query: 192 QKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDEC 251
           + A+ES   +D       T  N      S +          E + N T+   RE  H   
Sbjct: 270 KCAQESSQKQDG------TIQNLKETLKSRERETEELYQVIEGQ-NDTMAKLREMLHQSQ 322

Query: 252 QDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKE 311
              L+     G + +   V+++     L   + E+      +KL+  + +K++Q  + K+
Sbjct: 323 LGQLH--SSEGTSPAQQQVALLDLQSALFCSQLEI------QKLQRVVRQKERQLADAKQ 374

Query: 312 KCFLTQLSGFLANQQKKYKYEECKDLIKFM--LRNERQFKEEKLAEQLKQAEELRQYKVL 369
                + +   + QQK+  ++  ++L K +  L+ E Q K ++L     +A E  +Y   
Sbjct: 375 CVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQL-----RAWEAEKYNE- 428

Query: 370 VHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQH 428
           +  QE+ +  L   L       +   E LQ     Y  +  +  +  E L E  R   H
Sbjct: 429 IRTQEQNIQHLNHSLSHKEQLLQEFRELLQ-----YRDNSDKTLEANEMLLEKLRQRIH 482



 Score = 41.6 bits (96), Expect = 0.014
 Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 7/121 (5%)

Query: 1547 LEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 1603
            L  N + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 1604 -EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVE 1662
             EK  EVLQ  LD    TPS    L+DS +   S  ++ ++  +    DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEACSDMDIVSEYTHYE 1633

Query: 1663 E 1663
            E
Sbjct: 1634 E 1634



 Score = 41.6 bits (96), Expect = 0.014
 Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 7/121 (5%)

Query: 1791 LEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 1847
            L  N + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 1848 -EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVE 1906
             EK  EVLQ  LD    TPS    L+DS +   S  ++ ++  +    DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEACSDMDIVSEYTHYE 1633

Query: 1907 E 1907
            E
Sbjct: 1634 E 1634



 Score = 41.6 bits (96), Expect = 0.014
 Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 7/121 (5%)

Query: 2035 LEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 2091
            L  N + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 2092 -EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVE 2150
             EK  EVLQ  LD    TPS    L+DS +   S  ++ ++  +    DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEACSDMDIVSEYTHYE 1633

Query: 2151 E 2151
            E
Sbjct: 1634 E 1634



 Score = 41.6 bits (96), Expect = 0.014
 Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 7/121 (5%)

Query: 2279 LEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 2335
            L  N + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 2336 -EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVE 2394
             EK  EVLQ  LD    TPS    L+DS +   S  ++ ++  +    DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEACSDMDIVSEYTHYE 1633

Query: 2395 E 2395
            E
Sbjct: 1634 E 1634



 Score = 41.6 bits (96), Expect = 0.014
 Identities = 39/121 (32%), Positives = 57/121 (47%), Gaps = 7/121 (5%)

Query: 2523 LEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 2579
            L  N + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 2580 -EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVE 2638
             EK  EVLQ  LD    TPS    L+DS +   S  ++ ++  +    DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEACSDMDIVSEYTHYE 1633

Query: 2639 E 2639
            E
Sbjct: 1634 E 1634



 Score = 39.3 bits (90), Expect = 0.072
 Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 7/121 (5%)

Query: 813  LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 869
            L    + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 870  -EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVE 928
             EK  EVLQ  LD    TPS    L+DS +   S  ++ ++       DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEA--CSDMDIVSEYTHYE 1633

Query: 929  E 929
            E
Sbjct: 1634 E 1634



 Score = 39.3 bits (90), Expect = 0.072
 Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 7/121 (5%)

Query: 1057 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 1113
            L    + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 1114 -EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVE 1172
             EK  EVLQ  LD    TPS    L+DS +   S  ++ ++       DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEA--CSDMDIVSEYTHYE 1633

Query: 1173 E 1173
            E
Sbjct: 1634 E 1634



 Score = 39.3 bits (90), Expect = 0.072
 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 7/121 (5%)

Query: 1301 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 1357
            L    + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 1358 -EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDMDEIEKYQEVE 1416
             EK  EVLQ  LD    TPS    L+DS +   S  ++ ++  +    DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEACSDMDIVSEYTHYE 1633

Query: 1417 E 1417
            E
Sbjct: 1634 E 1634



 Score = 39.3 bits (90), Expect = 0.072
 Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 7/121 (5%)

Query: 2767 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 2823
            L    + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 2824 -EKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVE 2882
             EK  EVLQ  LD    TPS    L+DS +   S  ++ ++  +    DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEACSDMDIVSEYTHYE 1633

Query: 2883 E 2883
            E
Sbjct: 1634 E 1634



 Score = 38.5 bits (88), Expect = 0.12
 Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 7/121 (5%)

Query: 3330 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 3386
            L    + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 3387 -EKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVE 3445
             EK  EVLQ  LD    TPS    L DS +   S  ++ ++  +    DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEACSDMDIVSEYTHYE 1633

Query: 3446 E 3446
            E
Sbjct: 1634 E 1634



 Score = 38.1 bits (87), Expect = 0.16
 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 3121 KYQEVEEDQ---DPSCPRLSRELLD-EKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSA 3176
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L DS +   S 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 3177 FYILEQQRVGLAVDMDEIEKYQEVEE 3202
             ++ ++  +    DMD + +Y   EE
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEE 1634



 Score = 37.0 bits (84), Expect = 0.36
 Identities = 37/121 (30%), Positives = 55/121 (45%), Gaps = 7/121 (5%)

Query: 3011 LEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQ---NPPCPRLSRELLD 3067
            L    + + L     E+  +G +   R + K   +  K  E+DQ    P   RLSREL +
Sbjct: 1517 LRSNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKS-EKDQAGLEPLALRLSRELQE 1575

Query: 3068 -EKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVE 3126
             EK  +VLQ  LD    TPS    L DS +   S  ++ ++  +    DMD + +Y   E
Sbjct: 1576 KEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDE--LEACSDMDIVSEYTHYE 1633

Query: 3127 E 3127
            E
Sbjct: 1634 E 1634



 Score = 36.6 bits (83), Expect = 0.47
 Identities = 126/669 (18%), Positives = 256/669 (38%), Gaps = 153/669 (22%)

Query: 8    WSSEK------AEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYE 61
            W +EK       E NI  +N +L    + K+Q  +  +E          L  R    K  
Sbjct: 421  WEAEKYNEIRTQEQNIQHLNHSL----SHKEQLLQEFRE---------LLQYRDNSDKTL 467

Query: 62   ECKDLIKFMLRNERQFK--------EEKLAEQLKQAEELRQYKVLVHSQERELTQLREKL 113
            E  +++   LR     K        +EK +   ++ +ELRQ ++ V  ++ +L +LR+ L
Sbjct: 468  EANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVL 527

Query: 114  REGRDASRSL-----------------YEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQ 156
                   +S+                  ++LQ L    E   S+ Q  QE + +  + + 
Sbjct: 528  SSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSL 587

Query: 157  H------------LVQKLSPENDED-------------------EDEDVQVEEAEKVLES 185
            H            L+ KL P   E                     D + QV E E  ++ 
Sbjct: 588  HDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQG 647

Query: 186  SAPREVQKAEESKVPEDSLEECAITCSNSH--------GPCDSNQPHKNIKITFEEDEVN 237
                   + +ES+   + L + A+   NS         G  DS        I+ ++ EV 
Sbjct: 648  LLQSVSTREQESQAAAEKLVQ-ALMERNSELQALRQYLGGRDSLM--SQAPISNQQAEVT 704

Query: 238  STLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRP 297
             T  + +++     Q       +P    S +    + +   +S  ++ +  L+    L  
Sbjct: 705  PTGCLGKQTDQGSMQ-------IPSRDDSTS----LTAKEDVSIPRSTLGDLDTVAGLEK 753

Query: 298  QLAEKKQQFRNLKEK-----CFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEK 352
            +L+  K++   + +K       L+ L   +A Q+++ + +     ++ + RN  Q KE+ 
Sbjct: 754  ELSNAKEELELMAKKERESQMELSALQSMMAVQEEELQVQAAD--MESLTRN-IQIKEDL 810

Query: 353  LAE---QLKQAEELRQYKVLVHAQERELTQLKEKL----REGRDASRSLNEHLQALLTPY 405
            + +   QL   E++   + L     +E+  L+EK+     +G++ S +  + L  +L   
Sbjct: 811  IKDLQMQLVDPEDIPAMERLT----QEVLLLREKVASVESQGQEISGNRRQQLLLMLEGL 866

Query: 406  EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV-AEKVQKSSAPREMQK 464
              ++S+   L E L    +L   LV+  +    ++ D  +QVE+   +V +S     + +
Sbjct: 867  VDERSR---LNEALQAERQLYSSLVKFHAHPESSERDRTLQVELEGAQVLRSRLEEVLGR 923

Query: 465  AEEK------------EVPEDSLEECAITYSNSHGSYDSNQPHRK-TKITFEED------ 505
            + E+                D  E+ +  +++S     ++  H++  K+  E+       
Sbjct: 924  SLERLNRLETLAAIGGAAAGDDTEDTSTEFTDSIEEEAAHHSHQQLVKVALEKSLATVET 983

Query: 506  -----KVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES 560
                    S + G S+    E+ +H+  E     EE+ +          E E +E+  + 
Sbjct: 984  QNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQHLEEKRK---------AEEELKELKAQI 1034

Query: 561  WDEGYSTLS 569
             + G+S++S
Sbjct: 1035 EEAGFSSVS 1043



 Score = 35.4 bits (80), Expect = 1.0
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 923  KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 978
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 979  VYSLEEQYLGLALDVDRIKKDQEEEEDQGPP 1009
             +  +E  L    D+D + +    EE +  P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639



 Score = 35.4 bits (80), Expect = 1.0
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 1657 KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1712
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 1713 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPP 1743
             +  +E  L    D+D + +    EE +  P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639



 Score = 35.4 bits (80), Expect = 1.0
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 1901 KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1956
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 1957 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPP 1987
             +  +E  L    D+D + +    EE +  P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639



 Score = 35.4 bits (80), Expect = 1.0
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 2145 KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2200
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 2201 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPP 2231
             +  +E  L    D+D + +    EE +  P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639



 Score = 35.4 bits (80), Expect = 1.0
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 2389 KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2444
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 2445 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPP 2475
             +  +E  L    D+D + +    EE +  P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639



 Score = 35.4 bits (80), Expect = 1.0
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 2633 KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2688
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 2689 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPP 2719
             +  +E  L    D+D + +    EE +  P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639



 Score = 35.4 bits (80), Expect = 1.0
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 2877 KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 2933 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPP 2963
             +  +E  L    D+D + +    EE +  P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639



 Score = 35.4 bits (80), Expect = 1.0
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 3196 KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 3251
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 3252 VYSLEEQYLGLALDVDRIKKDQEEEEDQGPP 3282
             +  +E  L    D+D + +    EE +  P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639



 Score = 34.7 bits (78), Expect = 1.8
 Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 1167 KYQEVEEDQ---DPSCPRLSRELLD-EKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1222
            K  + E+DQ   +P   RLSREL + EK  EVLQ  LD    TPS    L D  +  SS 
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 1223 VYSLEEQYLGLALDVDRIKKDEEEEEDQDPP 1253
             +  +E  L    D+D + +    EE +  P
Sbjct: 1611 SFLSDE--LEACSDMDIVSEYTHYEEKKASP 1639



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 754  KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 809
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 810  FYALEEKHVGFSLDV 824
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 998  KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 1053
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 1054 FYALEEKHVGFSLDV 1068
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 1242 KDEEEEEDQ---DPPCPRLSRELLEVVAP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 1297
            KD + E+DQ   +P   RLSREL E     EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 1298 FYALEEKHVGFSLDV 1312
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 2708 KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 2763
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 2764 FYALEEKHVGFSLDV 2778
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 2952 KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 3007
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 3008 FYALEEKHVGFSLDV 3022
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 34.3 bits (77), Expect = 2.3
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 3271 KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 3326
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 3327 FYALEEKHVGFSLDV 3341
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 33.9 bits (76), Expect = 3.0
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 1732 KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 1787
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 1788 FYALEENHVGFSLDV 1802
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 33.9 bits (76), Expect = 3.0
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 1976 KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 2031
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 2032 FYALEENHVGFSLDV 2046
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 33.9 bits (76), Expect = 3.0
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 2220 KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 2275
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 2276 FYALEENHVGFSLDV 2290
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 33.9 bits (76), Expect = 3.0
 Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 4/75 (5%)

Query: 2464 KDQEEEEDQG---PPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 2519
            KD + E+DQ    P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 2520 FYALEENHVGFSLDV 2534
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 33.1 bits (74), Expect = 5.1
 Identities = 27/75 (36%), Positives = 38/75 (50%), Gaps = 2/75 (2%)

Query: 1486 KDQEEEEDE-DQDPPCPRLSRELLEVVEP-EVLQDSLDRCYSTPSSCLEQPDSCQPYGSS 1543
            KD + E+D+   +P   RLSREL E  +  EVLQ  LD    TPSS     DS +   S+
Sbjct: 1551 KDHKSEKDQAGLEPLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST 1610

Query: 1544 FYALEENHVGFSLDV 1558
             +  +E      +D+
Sbjct: 1611 SFLSDELEACSDMDI 1625



 Score = 32.7 bits (73), Expect = 6.7
 Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 14/128 (10%)

Query: 361  EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420
            E+ R+ +  +    RE +Q  E LRE   +SRS   HLQ L    E  K + Q L E L 
Sbjct: 1909 EDNRRLQAQLSHVSREHSQETESLREALLSSRS---HLQELEKELEHQKVERQQLLEDLR 1965

Query: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            E  +   H  ++     +ND     ++ + +           Q+ EEK+   +SL+    
Sbjct: 1966 EKQQEVLHFREERLSLQENDSRLQHKLVLLQ-----------QQCEEKQQLFESLQSELQ 2014

Query: 481  TYSNSHGS 488
             Y   +G+
Sbjct: 2015 IYEALYGN 2022


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 111/602 (18%), Positives = 232/602 (38%), Gaps = 65/602 (10%)

Query: 264 TSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLA 323
           T     +S+ +    +++E+ +    E+ EKLR   +EK +   N+KE            
Sbjct: 165 TKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL----------- 213

Query: 324 NQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEK 383
               K K E  K L+  +  N  Q       E  +Q EELR+ +  +  QE ++ + +E+
Sbjct: 214 ----KRKLERAKFLLPQVQTNTLQ------EEMWRQEEELREQEKKIRKQEEKMWRQEER 263

Query: 384 LREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDE 443
           LRE     R   E ++         + + ++ +++L E  +L +   Q    E    + E
Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323

Query: 444 DVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFE 503
           +   E  EK+ +       Q+ + +E  +   ++    +       +  +  R+ +  +E
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 383

Query: 504 EDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDE 563
           +++               +    + E E    E+EEK      N+ E EE+E  Q+   E
Sbjct: 384 QEE------KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 437

Query: 564 GYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSREL 623
               L    +M    +        + +Q+     +  +  W Q K  +QE        ++
Sbjct: 438 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE--KKMWRQEKMREQEDQMWEQEEKM 495

Query: 624 LDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAID------MDEI 677
            D++  +   D ++R +       E  +  +  +  +   E+ R             D+ 
Sbjct: 496 RDQE--QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQE 553

Query: 678 EKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYS 737
           EK +E E  ++        E +  ++ E +Q+  ++         E  +  Q     ++ 
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613

Query: 738 LEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCL 797
            EE            K  ++EEED+        +E +   + E +Q+  ++ +       
Sbjct: 614 QEE------------KMWEQEEEDK-----MQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656

Query: 798 EQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE---GEE 854
           EQ +  +         EEK  G    + E E+K +G++ +  R ++E+ RG++E   G+E
Sbjct: 657 EQEEKMREQ-------EEKMQGQEEKMREQEEKMQGQEEK-MREQEEKMRGQEEKMWGQE 708

Query: 855 DQ 856
           ++
Sbjct: 709 EK 710



 Score = 64.7 bits (156), Expect = 2e-09
 Identities = 117/566 (20%), Positives = 218/566 (38%), Gaps = 88/566 (15%)

Query: 9   SSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIK 68
           ++E+ +    E+ E LR   +EK +   N+KE                K K E  K L+ 
Sbjct: 181 TNEELKKKNAELQEKLRLAESEKSEIQLNVKEL---------------KRKLERAKFLLP 225

Query: 69  FMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQ 128
            +  N  Q       E  +Q EELR+ +  +  QE ++ +  E+LRE     R   E ++
Sbjct: 226 QVQTNTLQ------EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMR 279

Query: 129 ALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVL---ES 185
                    + + ++ +++L E  +L +   Q    E    E E+   E+ EK+    E 
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339

Query: 186 SAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDE--VNSTLVVD 243
              +E Q  E+ +   D  E             +  +  +  +  +E++E       + +
Sbjct: 340 LWEQEKQMREQEQKMRDQEER---MWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396

Query: 244 RESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKK 303
           RE    E ++ +                          +K E N+ E  EK       + 
Sbjct: 397 REKKMREEEETMR-------------------EQEEKMQKQEENMWEQEEK-------EW 430

Query: 304 QQFRNLKEKCFLTQLSGFLANQQKKYKYEE-CKDLIKFMLRNERQFKEEKLAEQ----LK 358
           QQ R  ++K  L +       ++K ++ EE  +D  +   + ++ +++EK+ EQ     +
Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490

Query: 359 QAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQ----- 413
           Q E++R  +  +  QE  + +  E+LRE  +  R   +  Q      E  K+Q Q     
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550

Query: 414 DLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPED 473
           D +E++ E  R+ +        E    ++E++  E  EK+Q+       Q+ +  E  E 
Sbjct: 551 DQEEKMREEERMRER-------EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK 603

Query: 474 SLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 533
             E+    +      ++            EEDK+          + WE     + E E  
Sbjct: 604 MQEQEEKMWEQEEKMWEQE----------EEDKMQ-----EQEEMMWEQE-EKMQEQEEK 647

Query: 534 DEEEEEKGPVSPRNLQESEEEEVPQE 559
             E+EEK       ++E EE+   QE
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQE 673



 Score = 40.0 bits (92), Expect = 0.042
 Identities = 39/227 (17%), Positives = 102/227 (44%), Gaps = 31/227 (13%)

Query: 8   WSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLI 67
           W  EK      ++ E    Q+ E++++ R+ ++K +  +   +  + + + K E  ++  
Sbjct: 469 WGQEKKMWRQEKMREQ-EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK 527

Query: 68  KFMLRNER-------QFKEEKLAEQLKQAEE----------LRQYKVLVHSQERELTQLR 110
           K   + E+       Q +E+K  +Q ++  E          +R+ + ++  QE ++ +  
Sbjct: 528 KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 587

Query: 111 EKLREG-----------RDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLV 159
           EK+RE            ++    ++E  + +   +E DK Q Q  +E + E     Q   
Sbjct: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ--EEMMWEQEEKMQEQE 645

Query: 160 QKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEE 206
           +K+  + ++  +++ ++ E E+ ++    +  ++ E+ +  E+ + E
Sbjct: 646 EKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE 692


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 66.6 bits (161), Expect = 4e-10
 Identities = 137/650 (21%), Positives = 257/650 (39%), Gaps = 89/650 (13%)

Query: 11   EKAEMNILEINETLRPQ-LAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKF 69
            +K + NI E+ E L  +  A +K Q   +  +  L +L       Q   + + CK     
Sbjct: 939  KKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLE----EEQIILEDQNCK----- 989

Query: 70   MLRNERQFKEEKLAE----QLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYE 125
             L  E++  E+++AE      ++ E+ +    L +  E  +T L E+LR   +  R   E
Sbjct: 990  -LAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRR-EEKQRQELE 1047

Query: 126  HLQALLTPDEPDKS-QGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEE--AEKV 182
              +  L  D  D S Q  +LQ Q+AE       L  +L+ + +E +    +VEE  A+K 
Sbjct: 1048 KTRRKLEGDSTDLSDQIAELQAQIAE-------LKMQLAKKEEELQAALARVEEEAAQKN 1100

Query: 183  LESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVV 242
            +     RE++ ++ S++ ED   E A          D  +  + +K T  ED ++ST   
Sbjct: 1101 MALKKIRELE-SQISELQEDLESERASRNKAEKQKRDLGEELEALK-TELEDTLDSTAA- 1157

Query: 243  DRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAE--MNILEINEKLRPQLA 300
             ++    + +  +NIL       + T+ + +       S+  E     LE  ++++  L 
Sbjct: 1158 -QQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE 1216

Query: 301  EKKQQFRN-----LKEKCFLTQLSGFLANQQKKYKYEECKDLIKFM-------------- 341
            + KQ   N       E   L Q  G   +++KK + +  +  +KF               
Sbjct: 1217 KAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVT 1276

Query: 342  -----------LRNERQFKEEKLAEQLKQAE-ELRQYKVLVHAQERELTQLKEKLREGRD 389
                       L ++   K  KL +     E +L+  + L+  + R+   L  KL++  D
Sbjct: 1277 KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336

Query: 390  ASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV 449
               S  E L       E ++    +L++Q+A    L   +        D+    +   EV
Sbjct: 1337 EKNSFREQL-------EEEEEAKHNLEKQIA---TLHAQVADMKKKMEDSVGCLETAEEV 1386

Query: 450  AEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRK---TKITFEEDK 506
              K+QK       Q+ EEK    D LE+              +  H++     +  ++ K
Sbjct: 1387 KRKLQKDLEGLS-QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445

Query: 507  VDSTLIG----SSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWD 562
             D  L      S+ + E  D        E++  E+E K     R L+E+ E++   E  +
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRA------EAEAREKETKALSLARALEEAMEQKAELERLN 1499

Query: 563  EGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQ 612
            + + T     ++++S      + H LE+ +  +   +   +    + ED+
Sbjct: 1500 KQFRTEM--EDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDE 1547



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 87/391 (22%), Positives = 156/391 (39%), Gaps = 49/391 (12%)

Query: 24   LRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLA 83
            L  Q+ E K Q   L+++   T+ A        K + E     +K     + Q ++E+  
Sbjct: 1530 LEQQVEEMKTQLEELEDELQATEDA--------KLRLEVNLQAMKAQFERDLQGRDEQSE 1581

Query: 84   EQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQD 143
            E+ KQ   +RQ    V   E EL   R++      A + L   L+ L    +       +
Sbjct: 1582 EKKKQL--VRQ----VREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDE 1635

Query: 144  LQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPE-- 201
              +QL +     +  +++L       E+   Q +E EK L+S     +Q  EE    E  
Sbjct: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695

Query: 202  -----DSLEECAITCSNSHGPCDSNQPHKN--------IKITFEEDEVNSTLVVDRESSH 248
                    +E A   +NS G        K         ++   EE++ N+ L+ DR    
Sbjct: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755

Query: 249  DECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRN 308
            +   D +N           T++++  S     +E A   +   N++L+ +L E +   ++
Sbjct: 1756 NLQIDQIN-----------TDLNLERSHAQ-KNENARQQLERQNKELKVKLQEMEGTVKS 1803

Query: 309  LKEKCFLTQLSGFLANQQKKYKYE--ECKDLIKFMLRNERQFKEEKLA--EQLKQAEELR 364
             K K  +T L   +A  +++   E  E +   K + R E++ K+  L   ++ + AE   
Sbjct: 1804 -KYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAE--- 1859

Query: 365  QYKVLVHAQERELTQLKEKLREGRDASRSLN 395
            QYK         L QLK +L E  + ++  N
Sbjct: 1860 QYKDQADKASTRLKQLKRQLEEAEEEAQRAN 1890



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 111/483 (22%), Positives = 196/483 (40%), Gaps = 68/483 (14%)

Query: 9    SSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECK-DLI 67
            S  + E+NIL+  +TL  +    + Q + +++K   +Q    LA + ++ K  +   +  
Sbjct: 1163 SKREQEVNILK--KTLEEEAKTHEAQIQEMRQKH--SQAVEELAEQLEQTKRVKANLEKA 1218

Query: 68   KFMLRNER-----------QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLR-- 114
            K  L NER           Q K +   ++ K   +L++ +V  +  ER  T+L +K+   
Sbjct: 1219 KQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKL 1278

Query: 115  ----EGRDASRSLYEHLQALLTPD-EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDED 169
                +      S  +   + LT D    +SQ QD QE L E  R    L  KL    DE 
Sbjct: 1279 QVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEK 1338

Query: 170  EDEDVQVEEAEKV---LESS-APREVQKAEESKVPEDSLEECAITCSNSHGPCDS----- 220
                 Q+EE E+    LE   A    Q A+  K  EDS+  C  T               
Sbjct: 1339 NSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSV-GCLETAEEVKRKLQKDLEGL 1397

Query: 221  NQPHKNIKITFEEDEVNST--------LVVDRESSHDECQDALNILPVPGPTSSATNVSM 272
            +Q H+     +++ E   T        L+VD +      Q A N+               
Sbjct: 1398 SQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQR---QSACNLEKKQKKFDQLLAEEK 1454

Query: 273  VVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYE 332
             +SA    +E+ +    E  EK    L+  +     +++K  L +L     N+Q + + E
Sbjct: 1455 TISA--KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERL-----NKQFRTEME 1507

Query: 333  ECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASR 392
            +       + ++  + ++ K A + +Q EE++           +L +L+++L+   DA  
Sbjct: 1508 DLMSSKDDVGKSVHELEKSKRALE-QQVEEMK----------TQLEELEDELQATEDAKL 1556

Query: 393  SLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEK 452
             L  +LQA+   +E D  QG+D Q +        + LV+++       +DE  Q  +A  
Sbjct: 1557 RLEVNLQAMKAQFERD-LQGRDEQSE-----EKKKQLVRQVREMEAELEDERKQRSMAVA 1610

Query: 453  VQK 455
             +K
Sbjct: 1611 ARK 1613


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 65.5 bits (158), Expect = 9e-10
 Identities = 102/526 (19%), Positives = 205/526 (38%), Gaps = 79/526 (15%)

Query: 84  EQLKQAEEL--------RQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDE 135
           E  KQ E+         ++Y  L   +E+EL++L+E +   R+ +R L +  Q + T  +
Sbjct: 138 EHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREENRQLRKAHQDIHTQLQ 197

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE-KVLESSAPREVQKA 194
             K Q ++L         L++H    ++ E+ +      Q + AE K L+ +  R     
Sbjct: 198 DVKQQHKNL---------LSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPSLR 248

Query: 195 EESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDA 254
           +     + ++ + A      H P   N   +      +E   N+ +  + E+     +D 
Sbjct: 249 KPDPAEQQNVTQVA------HSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAEDT 302

Query: 255 LNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKK----------- 303
                +  PT                 E+ E    ++ E+ R  L E++           
Sbjct: 303 ----KLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKALEEEEMEQVGQAEHLE 358

Query: 304 --------QQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLA- 354
                   +Q R  KE+    + +  L    +   Y   K +IKF    E Q ++++LA 
Sbjct: 359 EEHDPSPEEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAV 418

Query: 355 EQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQD 414
           +Q+++A++LR+++  +H Q  +   L+++ ++ +  +R +    QA L   E  + Q Q+
Sbjct: 419 QQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAEL---EEGRPQHQE 475

Query: 415 LQEQLAEGCRLAQHLVQKLSP----------ENDNDDDEDVQVEVAEKVQ-KSSAPREMQ 463
              Q A    +   +VQ              E DN   ++ + +   + + +   PRE  
Sbjct: 476 QLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREAD 535

Query: 464 KAEEKE---------------VPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVD 508
              E +                 ED  EE            D N+  +++    E  +V+
Sbjct: 536 PESEADRAAVEDINPADDPNNQGEDEFEEA--EQVREENLPDENEEQKQSNQKQENTEVE 593

Query: 509 STLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE 554
             L+ + +  + ED V    + E+++E +E+      R L+ + EE
Sbjct: 594 EHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEE 639



 Score = 61.2 bits (147), Expect = 2e-08
 Identities = 121/581 (20%), Positives = 235/581 (40%), Gaps = 74/581 (12%)

Query: 19  EINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFK 78
           ++ E  R Q  +  + F + K+K    Q       ++K+ +  + K+ +  +    RQ +
Sbjct: 134 DLEEEHRKQGEDFSRTFNDHKQKYLQLQ-------QEKEQELSKLKETVYNLREENRQLR 186

Query: 79  EEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPD---- 134
           +       +  +  +Q+K L+   E+ +  L +       A   + E+ Q   T +    
Sbjct: 187 KAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLNRIPS 246

Query: 135 --EPDKSQGQDLQE--QLAEGCRLAQHL----VQKLSPENDEDEDEDVQVEEAE------ 180
             +PD ++ Q++ +     +G   A+      VQ++S  ND  ++ +     AE      
Sbjct: 247 LRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYA 306

Query: 181 ---KVLESSAPRE-VQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKIT--FEED 234
              K  E  AP E +Q+  E + PE+   E        H      +  + +      EE+
Sbjct: 307 PTHKEAEFQAPPEPIQQEVERREPEEHQVE------EEHRKALEEEEMEQVGQAEHLEEE 360

Query: 235 EVNSTLVVDRE-SSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINE 293
              S    DRE     E ++A N+L             +  SA P+   ++        +
Sbjct: 361 HDPSPEEQDREWKEQHEQREAANLL------EGHARAEVYPSAKPMIKFQSPYEEQLEQQ 414

Query: 294 KLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKL 353
           +L  Q  E+ QQ R  +E     +L G L  QQ++ + +  +++    L+ + + +E + 
Sbjct: 415 RLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMA---LQRQAELEEGRP 471

Query: 354 AEQLKQAEELRQYKVLVHAQERELTQLKEK--LREGRDASRSLNEHL-QALLTP---YEP 407
             Q    E+LRQ +    A + ++ Q  E   ++    A    N+H  +A   P   +EP
Sbjct: 472 QHQ----EQLRQ-QAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEP 526

Query: 408 DKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAP--REMQKA 465
            + QG    +  +E  R A   V+ ++P +D ++  + + E AE+V++ + P   E QK 
Sbjct: 527 -REQGPREADPESEADRAA---VEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQ 582

Query: 466 EEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVH 525
             ++     +EE  +   N     D+     + +    E++V   L          +A  
Sbjct: 583 SNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEA---EEEVQEDLTEEKKRELEHNAEE 639

Query: 526 IIPENE-------SDDEEEEEKGPVSPRNLQESEEEEVPQE 559
              EN+       +D EE+E +    P+  +E  EEE  +E
Sbjct: 640 TYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEE 680



 Score = 39.7 bits (91), Expect = 0.055
 Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 5/130 (3%)

Query: 124 YEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVL 183
           +E  + +   + PD+++ Q    Q  E   + +HLV   +P+  ED  ++   EEAE+ +
Sbjct: 562 FEEAEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEV 621

Query: 184 ESSAPREVQK-----AEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNS 238
           +     E ++     AEE+    D   +            D N+P    +   EE+E   
Sbjct: 622 QEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEE 681

Query: 239 TLVVDRESSH 248
                 E SH
Sbjct: 682 DGAAVAEKSH 691



 Score = 37.0 bits (84), Expect = 0.36
 Identities = 50/247 (20%), Positives = 102/247 (41%), Gaps = 26/247 (10%)

Query: 324 NQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA--EELRQYKVLVHAQERELTQLK 381
           +Q  K ++EE K        ++ + +  K  E   +   +  ++Y  L   +E+EL++LK
Sbjct: 118 HQMLKSQHEELKKQ-----HSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLK 172

Query: 382 EKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDD 441
           E +   R+ +R L +  Q + T  +  K Q ++L         L++H    ++ E+    
Sbjct: 173 ETVYNLREENRQLRKAHQDIHTQLQDVKQQHKNL---------LSEHEQLVVTLEDHKSA 223

Query: 442 DEDVQVEVAEKVQ------KSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPH 495
               Q +VAE  Q      +  + R+   AE++ V + +        +    + +  +  
Sbjct: 224 LAAAQTQVAEYKQLKDTLNRIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVS 283

Query: 496 RKTKITFEEDKV----DSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQES 551
           R   +    + V    + T + + +H E E      P  +  +  E E+  V   + +  
Sbjct: 284 RNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEEHQVEEEHRKAL 343

Query: 552 EEEEVPQ 558
           EEEE+ Q
Sbjct: 344 EEEEMEQ 350


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 63.5 bits (153), Expect = 4e-09
 Identities = 136/657 (20%), Positives = 269/657 (40%), Gaps = 72/657 (10%)

Query: 18  LEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQF 77
           LE+ E  R  L EK  Q   ++++  + +LA  L N ++     E K+L +  LR++ + 
Sbjct: 235 LELAEN-RKLLTEKDAQIAMMQQR--IDRLA--LLNEKQAASPLEPKELEE--LRDKNES 287

Query: 78  KEEKLAEQLKQAEELRQYKVLVHSQERELTQ----LREKLREGRDASRSLYEHLQALLTP 133
              +L E LKQ ++L+  K  +  +  +L++    L  KLRE     + L + L  L   
Sbjct: 288 LTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEE 347

Query: 134 DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQK 193
                 +  + Q QL +    A    + L  +N+  + +  Q+EE    L+ + P+E  +
Sbjct: 348 HSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGE 407

Query: 194 AEESKVPEDSLEECAITCSNSHGP-------CDSNQPHKNIKIT-----FEEDEVN-STL 240
                +  ++L++ A T + ++          ++ +  +  K+      FEE++   S+L
Sbjct: 408 VLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSL 467

Query: 241 VVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLA 300
           + D +SS      A   L      S A    +      L+SE   +N     ++   +LA
Sbjct: 468 ITDLQSSISNLSQAKEELE---QASQAHGARLTAQVASLTSELTTLN--ATIQQQDQELA 522

Query: 301 EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
             KQQ +  + +   T      A+Q  +++ E+    +K   + E+Q KE  +AE+ +  
Sbjct: 523 GLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLK---QKEQQLKE--VAEKQEAT 577

Query: 361 EELRQYKVLVHAQERE---------LTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQ 411
            +    ++   A+ERE         L QL+   +E       L + LQ      +  ++ 
Sbjct: 578 RQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTS 637

Query: 412 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE-----KVQKSSAPREMQKAE 466
               Q + AE  R  + L  +   E    +  + Q +VAE     + ++  A  + + A+
Sbjct: 638 VTQAQREKAELSRKVEEL--QACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQ 695

Query: 467 EKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHI 526
           EK+  ++ L+    +   + GS +  +      +  ++  +      + S VE     H 
Sbjct: 696 EKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVE----QHK 751

Query: 527 IPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFH 586
               E ++E    KG +  R  Q  E  +   E          +    LA   +   T  
Sbjct: 752 RERKELEEERAGRKG-LEARLQQLGEAHQAETE----------VLRRELAEAMAAQHTAE 800

Query: 587 SLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLD-----EKGPEVFQDSQDR 638
           S E +Q+   V   R R++  ++E+ +  G     +L+      EK  +  Q+++++
Sbjct: 801 S-ECEQLVKEVAAWRERYEDSQQEEAQ-YGAMFQEQLMTLKEECEKARQELQEAKEK 855



 Score = 43.5 bits (101), Expect = 0.004
 Identities = 102/448 (22%), Positives = 180/448 (40%), Gaps = 56/448 (12%)

Query: 3    VSAGPWSSEKAEMNILEINET---LRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYK 59
            V+ G   +E+    I  + E    L  Q+ EK+ + + LK           +A  +K  K
Sbjct: 1213 VARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLV--------MAESEKSQK 1264

Query: 60   YEECKDLIKF--------------MLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERE 105
             EE   L++                LR E Q   E+  +Q   +E LRQ       +  E
Sbjct: 1265 LEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEE 1324

Query: 106  LTQ----LREKLREGRDASRSLY-EHL--QALLTPDEPDKSQGQDLQ-EQLAEGCRLAQH 157
            L Q     +EK  +   A  +L  EH   QAL++   P K   Q LQ EQ A   R  + 
Sbjct: 1325 LGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREE 1384

Query: 158  LVQ-KLSPENDEDEDEDVQVEEAEKV-LESSAPREVQKAEESKVPEDSLEECAITCSNSH 215
            L Q K +      E    Q E  E + L      + + A++ +  + S  E       +H
Sbjct: 1385 LEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAH 1444

Query: 216  GPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVS 275
            G        +N  +    +     L V+ + + ++    L  +       + T ++ V  
Sbjct: 1445 GLL----AEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRA----DAETRLAEVQR 1496

Query: 276  AGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCF--LTQLSGFLANQQKKYKYEE 333
                ++ + E+   +  E  + ++ E++Q+F+  ++K    + QL  F   Q K     +
Sbjct: 1497 EAQSTARELEVMTAKY-EGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTK-----Q 1550

Query: 334  CKDLIKFMLRNERQFK--EEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDAS 391
             ++L K +  +++  K  ++KL     Q  E +Q    + AQ   L +L+ +L +   A+
Sbjct: 1551 VEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQ---LNELQAQLSQKEQAA 1607

Query: 392  RSLNEHLQALLTPYEPDKSQGQDLQEQL 419
                  ++   T Y+  K Q Q+LQEQL
Sbjct: 1608 EHYKLQMEKAKTHYDAKKQQNQELQEQL 1635



 Score = 39.3 bits (90), Expect = 0.072
 Identities = 91/387 (23%), Positives = 147/387 (37%), Gaps = 82/387 (21%)

Query: 79   EEKLAEQLKQAE----ELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPD 134
            +E LA  L + E    EL + + L  +Q +EL +LR+ +++           L+  L   
Sbjct: 1049 QEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQ-----------LKEQLAKK 1097

Query: 135  EPDKSQGQDLQEQLA-----EGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR 189
            E + + G   Q + A      G +L + L  ++S    + + +  Q +  E+ LE+    
Sbjct: 1098 EKEHASGSGAQSEAAGRTEPTGPKL-EALRAEVSKLEQQCQKQQEQADSLERSLEAERAS 1156

Query: 190  EVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHD 249
              ++    +  +  LEE A    +S     S Q          E     T V D   + D
Sbjct: 1157 RAERDSALETLQGQLEEKAQELGHSQSALASAQ---------RELAAFRTKVQDHSKAED 1207

Query: 250  ECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEK---LRPQLAEKKQQF 306
            E +                     V+ G   +E+    I  + E+   L  Q+ EK+ + 
Sbjct: 1208 EWK-------------------AQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGES 1248

Query: 307  RNLKEKCFLTQLSGFLANQQKKYKYEECKDLIK--------------FMLRNERQFKEEK 352
            + LK           +A  +K  K EE   L++                LR E Q   E+
Sbjct: 1249 KELKRL--------VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREE 1300

Query: 353  LAEQLKQAEELRQ--YKVLVHAQE--RELTQLKEKLREGRDASRSLN-EH--LQALLTPY 405
              +Q   +E LRQ        A+E  +EL   +EK  +   A  +L  EH   QAL++  
Sbjct: 1301 AEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSEL 1360

Query: 406  EPDKSQGQDLQ-EQLAEGCRLAQHLVQ 431
             P K   Q LQ EQ A   R  + L Q
Sbjct: 1361 LPAKHLCQQLQAEQAAAEKRHREELEQ 1387


>gi|150010604 kinesin family member 4B [Homo sapiens]
          Length = 1234

 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 125/554 (22%), Positives = 220/554 (39%), Gaps = 85/554 (15%)

Query: 11   EKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFM 70
            ++ E  I ++ + L  Q    K +    +    L Q    + N++ +   +  +D  KF 
Sbjct: 603  QELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKF- 661

Query: 71   LRNERQFKEEKLAE--QLKQAEELRQYKVLVHSQ--ERELTQLREKLREGRDASRSLYEH 126
                RQ+K++K  E  QLK+ +  RQY++L   +  +++ + LR K  E   A++ L + 
Sbjct: 662  ----RQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDA 717

Query: 127  LQALLTPDEPDKSQGQDLQEQLAEGCR--LAQHLVQKLSPENDEDEDEDVQVEEAEKVLE 184
            LQ      +  K      +E +A   R  L   +   +S E  +    D+   E  K+L 
Sbjct: 718  LQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLL--EDRKILA 775

Query: 185  SSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQP--HKNIKITFEEDEVNSTLVV 242
                +  +K E  + P   L +C  + S  HG    ++    K I+    E E+ S  + 
Sbjct: 776  QDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIA 835

Query: 243  DRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEK 302
            D +      Q  L+      P     N++                ILE    L+  + E 
Sbjct: 836  DLQ------QKLLDAESEDRPKQCWENIA---------------TILEAKCALKYLIGEL 874

Query: 303  KQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFK--EEKLAEQLKQA 360
                  +  K  +T+L   L   +       C D+ K +   +  F   E +L  +L + 
Sbjct: 875  ------VSSKIHVTKLENSLRQSK-----ASCADMQKMLFEEQNHFSEIETELQAELVRM 923

Query: 361  EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLA 420
            E+  Q KVL    + + +Q+ EK  E     +S +E  Q L++  +    Q ++L E++ 
Sbjct: 924  EQQHQEKVLYLVSQLQESQMAEKQLE-----KSASEKEQQLVSTLQ---CQDEEL-EKMR 974

Query: 421  EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAI 480
            E C   Q L+Q    EN+    + + ++VA +              +K +P D+L    +
Sbjct: 975  EVCEQNQQLLQ----ENEIIKQKLILLQVASR--------------QKHLPNDTL----L 1012

Query: 481  TYSNSHGSYDSNQPHRKTKITFEEDKVD-STLIGSSSHV--EWEDAVHIIPENESDDEE- 536
            +  +S           + K  F E  +D   L   S H   E ED       +E DDEE 
Sbjct: 1013 SPDSSFEYIPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDEEW 1072

Query: 537  -EEEKGPVSPRNLQ 549
               +   VS +N+Q
Sbjct: 1073 KPTKLVKVSRKNIQ 1086


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 62.8 bits (151), Expect = 6e-09
 Identities = 162/781 (20%), Positives = 308/781 (39%), Gaps = 95/781 (12%)

Query: 23   TLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKE--- 79
            T R  L  K ++  + +E+    Q  G L   Q K   E    L + +   E + +    
Sbjct: 1383 TARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRG 1442

Query: 80   -----EKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPD 134
                 EK  E  K A EL    +   +QE +L Q  E+++E  +  RS+ EHL   +   
Sbjct: 1443 QIQELEKQREMQKAALELLSLDLKKRNQEVDLQQ--EQIQE-LEKCRSVLEHLPMAV--- 1496

Query: 135  EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKA 194
                   Q+ +++L       + L +    + +  E + +++E+ ++++ES    +VQ  
Sbjct: 1497 -------QEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRG-QVQDL 1548

Query: 195  EESKVPEDSLEECAITCSNSHGPCDSNQPH-KNIKITFEEDEVNST-LVVDRESSHDECQ 252
            ++  V   +LE  A+    +H   +  Q   K ++   E   V  T L +D E    E Q
Sbjct: 1549 KKQLV---TLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQ 1605

Query: 253  DALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEIN-EKLRPQLAEKKQQFRNLKE 311
               + +      S+     +      + S++ ++  L+   E L   L  + Q+    KE
Sbjct: 1606 AQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKE 1665

Query: 312  KCFLTQLSGFLANQQKKYKYEECKDLIKFMLRN-------ERQFKEEKLAE----QLKQA 360
            +    Q+      +Q K   EE  + IK  LR        +RQ  +E+  E       Q 
Sbjct: 1666 RI---QVLEDQRTRQTKI-LEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQR 1721

Query: 361  EELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQAL----------LTPYEPD-K 409
              L   K+++  +E+E+   +E + E ++    L + LQ L          L+  E +  
Sbjct: 1722 GSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIV 1781

Query: 410  SQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKE 469
               Q LQE   +G    Q L  +L          D ++E  ++ Q+ +  +E +  E+ +
Sbjct: 1782 VLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKAD 1841

Query: 470  VPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPE 529
              + +LE+  +T    HG     Q H++     EE+     L      V+   A+  +  
Sbjct: 1842 ALQGALEQAHMTLKERHGEL---QDHKEQARRLEEE-----LAVEGRRVQ---ALEEVLG 1890

Query: 530  NESDDEEEEEKG--PVSPRNLQESEEEEVP----QESWDEGYSTLSIPPEMLASYQSYSS 583
            +   +  E+EK    +  +  ++++E EV     Q+SW +  + L    + L + ++ S 
Sbjct: 1891 DLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQ 1950

Query: 584  TFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVFQDSQ-DRCYST 642
            +    EE     A  +            QEA G   +   L  K   + + ++  R    
Sbjct: 1951 SSRHQEEAARARAEAL------------QEALGK--AHAALQGKEQHLLEQAELSRSLEA 1996

Query: 643  PSGCLELT-DSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDE 701
             +  L+ + D+CQ +  +  + E  R+      D+  +YQE  +    +  +   EL  +
Sbjct: 1997 STATLQASLDACQAH--SRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQ 2054

Query: 702  KEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEED 761
            +E E L +         +   E  +LGQ         EE+  GL   V  ++    ++E 
Sbjct: 2055 QEREQLLEKSLAQRVQENMIQEKQNLGQERE------EEEIRGLHQSVRELQLTLAQKEQ 2108

Query: 762  Q 762
            +
Sbjct: 2109 E 2109



 Score = 49.7 bits (117), Expect = 5e-05
 Identities = 91/426 (21%), Positives = 182/426 (42%), Gaps = 57/426 (13%)

Query: 59   KYEECKDLIKFMLRNERQFKEE---KLAEQLKQAEELRQYKVLVHSQERELTQLREKLRE 115
            K EE    ++  LR+ ++ KEE   KL+E   Q E        +H + +   ++  +  +
Sbjct: 670  KAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQ 729

Query: 116  GRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQ 175
             ++A       L+  L   E D+   QDL EQL +G   A+ L++  S    + ++  ++
Sbjct: 730  EKEALVREKAALEVRLQAVERDR---QDLAEQL-QGLSSAKELLES-SLFEAQQQNSVIE 784

Query: 176  VEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDE 235
            V + +  ++     + ++  + +V    LE   +    S    + +   + +    + ++
Sbjct: 785  VTKGQLEVQIQTVTQAKEVIQGEVRCLKLE---LDTERSQAEQERDAAARQLA---QAEQ 838

Query: 236  VNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKL 295
               T +  ++++H++    +N L        + +   +  A     E  E   +E+  +L
Sbjct: 839  EGKTALEQQKAAHEK---EVNQLREKWEKERSWHQQELAKA----LESLEREKMELEMRL 891

Query: 296  RPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAE 355
            + Q  E +      +E+   TQ    L   Q + + E    L++ +L+ +++     LA+
Sbjct: 892  KEQQTEMEAIQAQREEE--RTQAESALCQMQLETEKERVS-LLETLLQTQKE-----LAD 943

Query: 356  QLKQAEELRQYKVLVHAQERELT------------QLKEKLREGRDASRSLNEHLQALLT 403
              +Q E LRQ   +   +E+E T            +LKE  R+ RD   +L E   +LL 
Sbjct: 944  ASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQ 1003

Query: 404  PYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQ 463
                 + Q +DL+ QL     +AQ   Q+L           V+ EV EK++++     +Q
Sbjct: 1004 DKMDLQKQVEDLKSQL-----VAQDDSQRL-----------VEQEVQEKLRETQEYNRIQ 1047

Query: 464  KAEEKE 469
            K  E+E
Sbjct: 1048 KELERE 1053



 Score = 48.9 bits (115), Expect = 9e-05
 Identities = 83/335 (24%), Positives = 136/335 (40%), Gaps = 37/335 (11%)

Query: 99   VHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQG----QDLQEQLAEGCRL 154
            V S   +L Q   K ++ RD  R   + L+  LT  E +KSQ     QDLQ QL++    
Sbjct: 1241 VASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQN--- 1297

Query: 155  AQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPR-EVQKAE---ESKVPEDSLEECAIT 210
             Q    K   + +  E E +++ E    L+S   R E+Q+ E   E ++ + + E     
Sbjct: 1298 -QEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQ 1356

Query: 211  CSNSHGPCDSNQPHKNIKITFEED--EVNSTLVVDRESSHDECQDALNILPVPGPTSSAT 268
              +        +   +     EED     S L +  E    E ++    L   G    A 
Sbjct: 1357 VEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESE-RERAQALQEQGELKVAQ 1415

Query: 269  NVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKK 328
              ++  +   L+   AE    E  E LR Q+ E ++Q    K    L  L     NQ+  
Sbjct: 1416 GKALQENLALLTQTLAERE--EEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVD 1473

Query: 329  YKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGR 388
             + E+ ++L K             + E L  A + R+ K+ V  +     Q++E L + R
Sbjct: 1474 LQQEQIQELEKC----------RSVLEHLPMAVQEREQKLTVQRE-----QIRE-LEKDR 1517

Query: 389  DASRSLNEH----LQALLTPYEPDKSQGQDLQEQL 419
            +  R++ EH    L+      E  + Q QDL++QL
Sbjct: 1518 ETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQL 1552



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 111/580 (19%), Positives = 230/580 (39%), Gaps = 66/580 (11%)

Query: 55   QKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQER----ELTQL- 109
            +K   + E +DL + + +N+ +  + +  +   ++E +  ++ +   Q R    EL ++ 
Sbjct: 1279 EKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRME 1338

Query: 110  ----REKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPE 165
                RE L+  ++   +  EHLQA +       S    L+E L    R A+  + KL  E
Sbjct: 1339 AQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDL----RTARSAL-KLKNE 1393

Query: 166  NDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHK 225
              E E E  Q  + +  L+ +  + +Q  E   +   +L E         G     +  +
Sbjct: 1394 EVESERERAQALQEQGELKVAQGKALQ--ENLALLTQTLAEREEEVETLRGQIQELEKQR 1451

Query: 226  NIK------ITFEEDEVNSTLVVDRESSH--DECQDALNILPVPGPTSSATNVSMVVSAG 277
             ++      ++ +  + N  + + +E     ++C+  L  LP+                 
Sbjct: 1452 EMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIR 1511

Query: 278  PLSSEK-AEMNILEIN----EKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYE 332
             L  ++  + N+LE      EK    +  ++ Q ++LK++  L  L       ++ +   
Sbjct: 1512 ELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQ--LVTLECLALELEENHHKM 1569

Query: 333  ECKDLIKFMLRNERQFKEEKLA----EQLKQAEELRQYKVLVHAQERELTQLKEKLREGR 388
            EC+  +   L  +R+ +   L     +  ++++EL+     +H  E   T L  +L+E  
Sbjct: 1570 ECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERD 1629

Query: 389  DASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND------NDDD 442
               +S  E ++ L    E      QDL+ +  E   L +  +Q L  +         +D 
Sbjct: 1630 QEVKSQREQIEELQRQKE---HLTQDLERRDQE-LMLQKERIQVLEDQRTRQTKILEEDL 1685

Query: 443  EDVQVEVAEKVQKSSAPREM--QKAEEKEVP----EDSLEECAITYSNSHGSYDSNQPHR 496
            E +++ + E+ ++ +  R++  ++AEE + P      SLE   +   +     +  Q H 
Sbjct: 1686 EQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHI 1745

Query: 497  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEE--- 553
              ++   +D+++  L G    V          E      + E++  V  + LQE+ E   
Sbjct: 1746 H-ELQELKDQLEQQLQGLHRKV---------GETSLLLSQREQEIVVLQQQLQEAREQGE 1795

Query: 554  --EEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQ 591
              E+  Q   DE    L+   + L + Q         EE+
Sbjct: 1796 LKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEER 1835



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 106/493 (21%), Positives = 197/493 (39%), Gaps = 66/493 (13%)

Query: 11   EKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFM 70
            +KAE    E+   LR    EK++  + L E                +++ E     ++  
Sbjct: 669  QKAEEAGAELQADLRDIQEEKEEIQKKLSES---------------RHQQEAATTQLE-Q 712

Query: 71   LRNERQFKEEKLAEQLKQAEELRQYK----VLVHSQERELTQLREKLREGRDASRSLYE- 125
            L  E + +EE LA  +++ E L + K    V + + ER+   L E+L +G  +++ L E 
Sbjct: 713  LHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQL-QGLSSAKELLES 771

Query: 126  ---HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKV 182
                 Q   +  E  K Q +   + + +   + Q  V+ L  E D +  +  Q  +A   
Sbjct: 772  SLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAAR 831

Query: 183  LESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVV 242
              + A +E + A E +      E   +            Q       + E +++   + +
Sbjct: 832  QLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRL 891

Query: 243  DRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEK 302
              + +  E   A             T     +    L +EK  +++LE   + + +LA+ 
Sbjct: 892  KEQQTEMEAIQAQR-------EEERTQAESALCQMQLETEKERVSLLETLLQTQKELADA 944

Query: 303  KQQFRNLKEKCFLTQL-----SGFLANQQKKYKYE------ECKDLIKFMLRNERQFKEE 351
             QQ   L++   + +L     +G L  Q ++ + E      + +D +  +        ++
Sbjct: 945  SQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQD 1004

Query: 352  KLAEQLKQAEELRQYKVLVHAQERELTQ-LKEKLREGRDASR--------------SLNE 396
            K+  Q KQ E+L+   V     +R + Q ++EKLRE ++ +R              SL E
Sbjct: 1005 KMDLQ-KQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLME 1063

Query: 397  HLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKS 456
              Q LL   E D  + Q+L   L +  + AQ   ++LS +      E ++ EV EK +  
Sbjct: 1064 KEQRLLVLQEADSIRQQEL-SALRQDMQEAQGEQKELSAQM-----ELLRQEVKEK-EAD 1116

Query: 457  SAPREMQKAEEKE 469
               +E Q  EE E
Sbjct: 1117 FLAQEAQLLEELE 1129



 Score = 38.9 bits (89), Expect = 0.094
 Identities = 50/210 (23%), Positives = 89/210 (42%), Gaps = 28/210 (13%)

Query: 8    WSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLI 67
            W  E++  +  E+ + L     EK +    LKE+   T++    A R+++    E   L 
Sbjct: 862  WEKERS-WHQQELAKALESLEREKMELEMRLKEQ--QTEMEAIQAQREEERTQAESA-LC 917

Query: 68   KFMLRNERQF---------KEEKLAEQLKQAEELRQYKVLVHSQERELT----------- 107
            +  L  E++           +++LA+  +Q E LRQ   +   +E+E T           
Sbjct: 918  QMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQ 977

Query: 108  -QLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLA---EGCRLAQHLVQKLS 163
             +L+E  R+ RD   +L E   +LL      + Q +DL+ QL    +  RL +  VQ+  
Sbjct: 978  RELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKL 1037

Query: 164  PENDEDEDEDVQVEEAEKVLESSAPREVQK 193
             E  E      ++E  +  L  S   + Q+
Sbjct: 1038 RETQEYNRIQKELEREKASLTLSLMEKEQR 1067



 Score = 33.5 bits (75), Expect = 3.9
 Identities = 104/494 (21%), Positives = 176/494 (35%), Gaps = 76/494 (15%)

Query: 46  QLAGFLANRQK--KYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEEL-RQYKVLVHSQ 102
           QL   LA  Q+  K  +E  ++LI+  L+++   ++ +L +++ +   L  Q +      
Sbjct: 245 QLLLLLAKTQELEKEAHERSQELIQ--LKSQGDLEKAELQDRVTELSALLTQSQKQNEDY 302

Query: 103 ERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDL-----QEQLAEGCRLAQH 157
           E+ +  LRE +         L EH  +L    + +K   Q +     Q  + EG  +AQ 
Sbjct: 303 EKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQG 362

Query: 158 LVQKLSPENDEDEDEDVQVEEAEKVL---ESSAPREVQKAEESKVPEDSLEECAITCSNS 214
              + S E D         ++A+K L    S   R  Q  ++ +      +E        
Sbjct: 363 SGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQ 422

Query: 215 HGPCDSNQP---HKNIKITFEED-----------EVNSTLVVDRE---SSHDECQDALNI 257
           H   +        +  K+T E D           EV+S L  +RE    + +E +  L +
Sbjct: 423 HDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDS-LSKERELLQKAREELRQQLEV 481

Query: 258 LPVPGPTSSATNVSMVVSAGPLSSEKAEMNI---LEINEKLRPQ---------LAEKKQQ 305
           L          NV + +       +K E      L + E+ R Q          +E   +
Sbjct: 482 LEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSE 541

Query: 306 FRNLKEKCFLTQLSGFLANQQKKY---KYEECKDLIKFMLRNERQFKEEK---------- 352
              L+E    + L G L  Q++          +  I  +  +E   K E           
Sbjct: 542 LITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKL 601

Query: 353 -------------LAEQLKQAEELRQYKVL-VHAQERELTQLKEKLREG---RDASRSLN 395
                        L +QL Q EE  Q     + A E+    L+  L E    R+A    N
Sbjct: 602 SALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKN 661

Query: 396 EHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 455
            HL+A L   E     G +LQ  L +     + + +KLS      +    Q+E   +  K
Sbjct: 662 THLEAQLQKAE---EAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAK 718

Query: 456 SSAPREMQKAEEKE 469
                  +  +EKE
Sbjct: 719 RQEEVLARAVQEKE 732


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 110/581 (18%), Positives = 245/581 (42%), Gaps = 86/581 (14%)

Query: 10  SEKAE--MNILEINETL-RPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDL 66
           SEK+E  +N+ E+   L R +    + Q   L+E+ +  +    L  ++KK + +E K  
Sbjct: 239 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE--LREQEKKIRKQEEK-- 294

Query: 67  IKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREG---RDASRSL 123
              M R E + +E++  +  +Q E++ + +  +  QE+EL +  ++LRE    R+    +
Sbjct: 295 ---MWRQEERLREQE-GKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQM 350

Query: 124 YEHLQALLTPDEPDKSQGQDL---QEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180
            E  + +   +E  + Q + +   +E+L E  +  +   QK+  + +   ++D ++ E E
Sbjct: 351 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 410

Query: 181 KVLESSAP--REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEV-- 236
           + +        +V+K  E K  ++  ++   T        +  +  +  K   EE+E   
Sbjct: 411 ERMREQEKMWEQVEKMREEKKMQEQEKK---TRDQEEKMQEEERIREREKKMREEEETMR 467

Query: 237 --NSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEK 294
                +    E+  ++ +       +P           +        ++ E  I E  EK
Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM--------QEQEEKIWEQEEK 519

Query: 295 LRPQ---LAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEE 351
           +R Q     ++K+ +R  K    + +    +  Q++K + +E K      + ++ +  E+
Sbjct: 520 IRDQEEMWGQEKKMWRQEK----MREQEDQMWEQEEKMRDQEQK------MWDQEERMEK 569

Query: 352 KLAEQLK----QAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEP 407
           K  EQ K    Q E++R+        E  + + ++K+RE  +  R   E +Q      + 
Sbjct: 570 KTQEQEKKTWDQEEKMRE--------EERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621

Query: 408 DKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKV---QKSSAPREMQK 464
            + +  + +E++ E         +K+  + +   ++    E  EK+   +K     +MQ+
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQE 681

Query: 465 AEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAV 524
            EEK   ++ +E+               +   + K T++++K+           +  +  
Sbjct: 682 QEEKIWEQEKMEK---------------KTQEQEKKTWDQEKMREEESMREREKKMREEE 726

Query: 525 HIIPENESDDEEEEEKGPVSPRNLQESEEE--EVPQESWDE 563
            ++ E E   +E+EEK       +QE EEE  E  ++ W++
Sbjct: 727 EMMREQEEKMQEQEEK-------MQEQEEEMWEQEEKMWEQ 760



 Score = 52.0 bits (123), Expect = 1e-05
 Identities = 72/337 (21%), Positives = 136/337 (40%), Gaps = 36/337 (10%)

Query: 281 SEKAE--MNILEINEKL-RPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDL 337
           SEK+E  +N+ E+  KL R +    + Q   L+E+ +  +    L  Q+KK + +E K  
Sbjct: 239 SEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE--LREQEKKIRKQEEK-- 294

Query: 338 IKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEH 397
              M R E + +E++  +  +Q E++ + +  +  QE+EL + +++LRE ++      + 
Sbjct: 295 ---MWRQEERLREQE-GKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQM 350

Query: 398 LQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKV-QKS 456
            +     +E ++   +  ++   +  RL +   Q    E    D E+   E  E++ +K 
Sbjct: 351 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 410

Query: 457 SAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSS 516
              RE +K  E+   E   EE  +            +   + +I   E K+         
Sbjct: 411 ERMREQEKMWEQV--EKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMR-------- 460

Query: 517 HVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLA 576
                       E E    E+EEK      N+ E EE+E  Q+   E    L    +M  
Sbjct: 461 ------------EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 508

Query: 577 SYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQE 613
             +        + +Q+     +  +  W Q K  +QE
Sbjct: 509 QEEKIWEQEEKIRDQEEMWGQE--KKMWRQEKMREQE 543



 Score = 40.0 bits (92), Expect = 0.042
 Identities = 70/417 (16%), Positives = 173/417 (41%), Gaps = 42/417 (10%)

Query: 27  QLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQL 86
           Q+ E++Q+ R+ +E+ +         + + + K E  ++  K   + E+  +E+K+ EQ 
Sbjct: 384 QMREQEQKMRDQEERMWEQ-------DERLREKEERMREQEKMWEQVEKMREEKKMQEQE 436

Query: 87  KQA---EELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHL--------QALLTPDE 135
           K+    EE  Q +  +  +E+++ +  E +RE  +  +   E++        Q    P++
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQ----------KLSPENDEDEDEDVQVEEAEKVLES 185
            +K   Q+  ++  E     +  ++          K+  +    E ED   E+ EK+ + 
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556

Query: 186 SAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRE 245
               +    +E ++ + + E+   T        +  +  +  K   EE+E+        +
Sbjct: 557 E---QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 613

Query: 246 SSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEM----NILEINEKL-RPQLA 300
              ++ Q+    +             M      +  ++ +M     + E  EKL   +  
Sbjct: 614 EQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673

Query: 301 EKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQA 360
           +++++ +  +EK +  +       +Q+K  +++ K   +  +R   +   E+     +Q 
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733

Query: 361 EELRQYKVLVHAQERELTQLKEKLREGRD---ASRSLNEHLQALLTPYEPDKSQGQD 414
           E++++ +  +  QE E+ + +EK+ E  +     + L E  + L   +E +K Q Q+
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL---WEHEKMQEQE 787


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 165/819 (20%), Positives = 311/819 (37%), Gaps = 116/819 (14%)

Query: 20   INETLR---PQLAEKKQQFR-----NLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFML 71
            IN+ L+    ++ EK++QF       ++EK  + +L  F  +R+ K    +  +     L
Sbjct: 1517 INDKLQNKIQEIYEKEEQFNIKQISEVQEK--VNELKQFKEHRKAKDSALQSIESKMLEL 1574

Query: 72   RNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ-LREKLREGRDASRSLYEHLQAL 130
             N  Q  +E++   +K+ EE+++ +  +  +  +L +  +E + + +++    Y+ L+  
Sbjct: 1575 TNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMT 1634

Query: 131  LTPDEPDK------------SQGQDLQEQLAEGCRLAQHLVQKLSPEND--EDEDEDVQV 176
               +  +K            +Q  +L+    E  RL Q L + L       ++ D+   V
Sbjct: 1635 AVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSV 1694

Query: 177  EEAEKV--------LESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIK 228
            EE  KV        L  +  R+++K EE K+    L+E   T     G            
Sbjct: 1695 EETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRG------------ 1742

Query: 229  ITFEEDEVNSTLVVDRESSHD-------ECQDALNI--LPVPGPTSSATNVSMVVSAGPL 279
            I  E+    S +  D E S+D       + Q+ L I  + +     +   +  +VS    
Sbjct: 1743 IVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTD 1802

Query: 280  SSEKAEMNILEINEKLRPQLAEKK---QQFRNLKEKCFLTQLSGFLANQQKKYKYEECKD 336
                 + ++   N KL+ ++ E K    Q   LK+    TQ       Q KK   ++   
Sbjct: 1803 KLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT 1862

Query: 337  LIKFMLRNER--QFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSL 394
            L K  + N    Q   E L E     +E    + +    + E  QLKE L+E +     +
Sbjct: 1863 LSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI 1922

Query: 395  NEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQ 454
             + L+      +  K     L+E+++E        +Q    + D D  +D   E+ +K+Q
Sbjct: 1923 QQELKTARMLSKEHKETVDKLREKISE------KTIQISDIQKDLDKSKD---ELQKKIQ 1973

Query: 455  ------------KSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITF 502
                        K       +K  E E  +   E  A   S      D+ Q  +K   + 
Sbjct: 1974 ELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFE--AQNLSMQSVRMDNFQLTKKLHESL 2031

Query: 503  EEDKV------DSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEV 556
            EE ++      +   I  S  +E +  +  + E  + D +  +   V P     S+ ++ 
Sbjct: 2032 EEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQ---VKPEKRLLSDGQQH 2088

Query: 557  PQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATG 616
              ES  E  S +    E+L  Y      +  L    + +  +I      + +KE      
Sbjct: 2089 LTESLREKCSRIK---ELLKRYSEMDDHYECLNRLSLDLEKEI------EFQKELSMRVK 2139

Query: 617  PRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGL---AID 673
              LS   L  K  E    +  RC       ++       Y +   I E+Q   +    +D
Sbjct: 2140 ANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTK--IKEEQHESINKFEMD 2197

Query: 674  -MDEIEKYQEVE---EDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQ 729
             +DE+EK +E+    +     C   SREL D K  + +   ++      S   E P +  
Sbjct: 2198 FIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSES-EFPSIKT 2256

Query: 730  PYSSAVYSLEE------QYLGLALDVDRIKKDQEEEEDQ 762
             +   + + +E      ++L    D++++K   ++E D+
Sbjct: 2257 EFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDR 2295



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 120/604 (19%), Positives = 242/604 (40%), Gaps = 76/604 (12%)

Query: 19   EINETLRPQLAEKKQQFRNLKEKCFLT-------QLAGFLANRQKKYKYEECKDLIKFML 71
            E+ + L   +AEK+Q   +LKE   +T       +L G    +Q++   +E    IK   
Sbjct: 1054 ELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEG 1113

Query: 72   RNERQFK-----EEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSL--- 123
               R        EEKL E+ +Q +E +Q   L++ QE E++++++K+ E  +    L   
Sbjct: 1114 ELSRTCDRLAEVEEKLKEKSQQLQEKQQQ--LLNVQE-EMSEMQKKINEIENLKNELKNK 1170

Query: 124  ---YEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDED 173
                EH++          ++  +  + + +  ++ + L +    E D       E E   
Sbjct: 1171 ELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATG 1230

Query: 174  VQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEE 233
            +Q +E  K+         +  +E +      E+ A   +         +  + I +  EE
Sbjct: 1231 LQTKEELKIAHIHLKEHQETIDELR--RSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEE 1288

Query: 234  DEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINE 293
             E+     V   S   E  + L +L     T  +T ++ +           EM  L +NE
Sbjct: 1289 QELLPN--VKEVSETQETMNELELLTEQSTTKDSTTLARI-----------EMERLRLNE 1335

Query: 294  KLRPQLAEKKQQFRNL-KEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFK--- 349
            K +    E +++ ++L KE+  L  +   L  +  + K    + L K      +Q +   
Sbjct: 1336 KFQ----ESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLN 1391

Query: 350  -EEKLAEQLKQAEELRQYKVLVHAQ---ERELTQLKEKLREGRDASRSLNEHLQALLTPY 405
             +EK  E  K   E+ Q+K    A    E E+  L ++L+E  D  +S+ +    L    
Sbjct: 1392 MKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQ 1451

Query: 406  EPDKSQGQDLQEQLAEGCRLAQHL-------VQKLSPENDNDDDEDVQVEVAEK-VQKSS 457
            E  +S+   L+E + E   +A+HL       V     +   +   +++V ++EK  + S+
Sbjct: 1452 EVLQSESDQLKENIKE--IVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEIST 1509

Query: 458  APREMQKAEEK---------EVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVD 508
              ++++   +K         E  E    +               + HRK K +  +    
Sbjct: 1510 IQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIES 1569

Query: 509  STLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVP--QESWDEGYS 566
              L  ++   E ++ + I+ + + + +  +E   +    L+E+ +E V   +ES ++ Y 
Sbjct: 1570 KMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQ 1629

Query: 567  TLSI 570
             L +
Sbjct: 1630 FLKM 1633



 Score = 51.2 bits (121), Expect = 2e-05
 Identities = 123/684 (17%), Positives = 273/684 (39%), Gaps = 67/684 (9%)

Query: 103  ERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKL 162
            E E  +L EK +E ++  +SL +    L T  E  + +   L+E + E     Q      
Sbjct: 1327 EMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQ------ 1380

Query: 163  SPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQ 222
              E+   +++ + ++E +    +   + V + E+ K  + +L    I           + 
Sbjct: 1381 --ESQSKQEQSLNMKEKD----NETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQES- 1433

Query: 223  PHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSE 282
             H  +K   +E +    L    +S  D+ ++ +  +         T   + V+   L  +
Sbjct: 1434 -HDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAK---HLETEEELKVAHCCLKEQ 1489

Query: 283  KAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFML 342
            +  +N L +N      L+EK+ +   ++++  L  ++  L N+            I+ + 
Sbjct: 1490 EETINELRVN------LSEKETEISTIQKQ--LEAINDKLQNK------------IQEIY 1529

Query: 343  RNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALL 402
              E QF  ++++E  ++  EL+Q+K    A++  L  ++ K+ E  +  +   E +Q ++
Sbjct: 1530 EKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMI 1589

Query: 403  TPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREM 462
               E  K   + LQ +  +     + +V K+  E+   + + +++    + Q+     E 
Sbjct: 1590 KEKEEMKRVQEALQIERDQLKENTKEIVAKMK-ESQEKEYQFLKMTAVNETQEKMCEIEH 1648

Query: 463  QKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWED 522
             K E+ E  + +LE               N    ++ +T E D + S  +  +  VE + 
Sbjct: 1649 LK-EQFETQKLNLENIETENIRLTQILHENLEEMRS-VTKERDDLRS--VEETLKVERDQ 1704

Query: 523  AVHIIPENESDDEEEEEKGPVSPRNLQESEE-------------EEVPQESWDEGYSTLS 569
                + E  + D E++E+  +   +L+E +E              E+     D  +S  +
Sbjct: 1705 LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA 1764

Query: 570  IPPEMLASYQSYSSTFHSLEEQQ--VCMAVDIGRHRWDQVK--KEDQEATGPRLSRELLD 625
            +  + L   +        L+EQQ  +     I   + D++   ++D E +  +L  ++ +
Sbjct: 1765 LKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQE 1824

Query: 626  EKGPE----VFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDE-IEKY 680
             K  E      +   +      S   +L    +        LE + + LA  + E +E+ 
Sbjct: 1825 LKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEM 1884

Query: 681  QEVEEDQDPSCPRLSRELLDEKE--PEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSL 738
            + V +++D +  R+   L  E++   E LQ++  R             L + +   V  L
Sbjct: 1885 KSVMKERD-NLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKL 1943

Query: 739  EEQYLGLALDVDRIKKDQEEEEDQ 762
             E+     + +  I+KD ++ +D+
Sbjct: 1944 REKISEKTIQISDIQKDLDKSKDE 1967



 Score = 43.1 bits (100), Expect = 0.005
 Identities = 107/500 (21%), Positives = 207/500 (41%), Gaps = 78/500 (15%)

Query: 9    SSEKAEMNILEI-NETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLI 67
            S ++  +N+ E  NET +  +  + +QF+         ++     +++ +  ++E K + 
Sbjct: 1384 SKQEQSLNMKEKDNETTK--IVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVA 1441

Query: 68   KF---------MLRNER-QFKE---EKLAEQLKQAEELRQYKVLVHSQERELTQLREKLR 114
            K          +L++E  Q KE   E +A+ L+  EEL+     +  QE  + +LR  L 
Sbjct: 1442 KEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLS 1501

Query: 115  EGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV 174
            E      ++ + L+A+      DK Q +                +Q++  + ++   + +
Sbjct: 1502 EKETEISTIQKQLEAI-----NDKLQNK----------------IQEIYEKEEQFNIKQI 1540

Query: 175  QVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEED 234
              E  EKV E    +E +KA++S +   S+E   +  +N        +  + I+I  +E 
Sbjct: 1541 S-EVQEKVNELKQFKEHRKAKDSAL--QSIESKMLELTNR-----LQESQEEIQIMIKEK 1592

Query: 235  E----VNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE 290
            E    V   L ++R+   +  ++   I+     +       + ++A   + EK    + E
Sbjct: 1593 EEMKRVQEALQIERDQLKENTKE---IVAKMKESQEKEYQFLKMTAVNETQEK----MCE 1645

Query: 291  INEKLRPQLAEKKQQFRNLK-EKCFLTQ-LSGFLANQQKKYKYEECKDLIKFMLRNERQF 348
            I E L+ Q   +K    N++ E   LTQ L   L   +   K  +    ++  L+ ER  
Sbjct: 1646 I-EHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQ 1704

Query: 349  KEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPD 408
             +E L E + +  E ++   +VH   +E  +  +KLR       +   ++Q  L  +  D
Sbjct: 1705 LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDL-EHSND 1763

Query: 409  KSQGQDLQEQLAEGCRLA-------QHLVQKL---------SPENDNDDDEDVQVEVAEK 452
              + QDL+ Q  E  R+A       Q  + KL            N   D E+   ++ EK
Sbjct: 1764 ALKAQDLKIQ--EELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEK 1821

Query: 453  VQKSSAPREMQKAEEKEVPE 472
            +Q+  A        +K+V E
Sbjct: 1822 IQELKANEHQLITLKKDVNE 1841



 Score = 37.7 bits (86), Expect = 0.21
 Identities = 107/511 (20%), Positives = 199/511 (38%), Gaps = 82/511 (16%)

Query: 30   EKKQQFRNLKEKCFLTQLAGFLANRQKK-------YKYEECKDLIKFM------LRNERQ 76
            EK++    LKEK  L +    L  + KK       ++    K+L+K        L NE  
Sbjct: 520  EKEEMELKLKEKNDLDEFEA-LERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELS 578

Query: 77   FKEEKLAEQLKQAEELRQYKVLVHSQERE-----LTQLREKLREGRDASRSLYEHLQALL 131
             K E L E+  Q ++L++Y   + SQ+ E     L+   E + + +   ++L++     L
Sbjct: 579  SKVELLREKEDQIKKLQEY---IDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVAL 635

Query: 132  TPDEPD---KSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAP 188
                     +S+  +L+E++ E     + +   +     + E +     + EK L+S A 
Sbjct: 636  DAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQS-AF 694

Query: 189  REVQKAE---ESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNS---TLVV 242
             E+ K     + KVP+D L    +    +    + N+  +  +   EE  + S   +L  
Sbjct: 695  NEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPS 754

Query: 243  DRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEK 302
            + E    E QD    L +       T+    + +  +  E     +LE   K +  LA  
Sbjct: 755  EVERLRKEIQDKSEELHI------ITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATT 808

Query: 303  K-------QQFRNLKE---------KCFLTQ---LSGFLANQQKK-YKYEECKDLIKFML 342
            +       Q+F+N K          K  L +   ++  + N  K+  K++     +K  L
Sbjct: 809  QSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTEL 868

Query: 343  RNERQFKEEKLAEQLKQAEELRQYKVLVHAQ-------ERELTQLKEKLR---------- 385
              + Q  +EK  E  ++  E+ Q K  +  +       ERE T + EKL+          
Sbjct: 869  SYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLT 928

Query: 386  EGRDASRSLNEHLQ----ALLTPYEPDKSQGQDLQEQL---AEGCRLAQHLVQKLSPEND 438
            + +D  + L E LQ     L +      +   D QEQL    E  +  Q  +  L  +  
Sbjct: 929  QEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKIS 988

Query: 439  NDDDEDVQVEVAEKVQKSSAPREMQKAEEKE 469
             +   ++ +E      K    ++M   ++K+
Sbjct: 989  EEVSRNLHMEENTGETKDEFQQKMVGIDKKQ 1019


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.133    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 170,525,009
Number of Sequences: 37866
Number of extensions: 9567729
Number of successful extensions: 63438
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 685
Number of HSP's that attempted gapping in prelim test: 46085
Number of HSP's gapped (non-prelim): 11206
length of query: 3628
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3506
effective length of database: 13,627,866
effective search space: 47779298196
effective search space used: 47779298196
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 72 (32.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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