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Search of human proteins with 224586777
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224586777 WD repeat domain 8 [Homo sapiens]
(460 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224586777 WD repeat domain 8 [Homo sapiens] 961 0.0
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 47 5e-05
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 45 1e-04
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 45 1e-04
gi|31317278 WD repeat domain 20 isoform 3 [Homo sapiens] 45 2e-04
gi|31317276 WD repeat domain 20 isoform 4 [Homo sapiens] 45 2e-04
gi|31317274 WD repeat domain 20 isoform 1 [Homo sapiens] 45 2e-04
gi|31317280 WD repeat domain 20 isoform 2 [Homo sapiens] 45 2e-04
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 44 4e-04
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ... 41 0.003
gi|157384984 transducin-like enhancer protein 3 isoform c [Homo ... 41 0.003
gi|157384982 transducin-like enhancer protein 3 isoform a [Homo ... 41 0.003
gi|223005862 echinoderm microtubule associated protein like 6 [H... 40 0.003
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 40 0.003
gi|4757988 WD repeat domain 39 [Homo sapiens] 40 0.004
gi|23199987 WD repeat domain 5B [Homo sapiens] 39 0.013
gi|26665869 WD repeat domain 51B [Homo sapiens] 38 0.017
gi|16554629 WD repeat domain 5 [Homo sapiens] 37 0.029
gi|16554627 WD repeat domain 5 [Homo sapiens] 37 0.029
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 37 0.038
gi|102470001 PQQ repeat and WD repeat domain containing [Homo sa... 37 0.038
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 37 0.038
gi|209969680 Fzr1 protein isoform 1 [Homo sapiens] 37 0.049
gi|209969678 Fzr1 protein isoform 3 [Homo sapiens] 37 0.049
gi|33620742 Fzr1 protein isoform 2 [Homo sapiens] 37 0.049
gi|19913367 transducin beta-like 1Y [Homo sapiens] 37 0.049
gi|19913365 transducin beta-like 1Y [Homo sapiens] 37 0.049
gi|15150805 transducin beta-like 1Y [Homo sapiens] 37 0.049
gi|147904340 WD repeat domain 82 [Homo sapiens] 36 0.064
gi|145279222 WD repeat domain 66 [Homo sapiens] 36 0.064
>gi|224586777 WD repeat domain 8 [Homo sapiens]
Length = 460
Score = 961 bits (2483), Expect = 0.0
Identities = 460/460 (100%), Positives = 460/460 (100%)
Query: 1 MNFSEVFKLSSLLCKFSPDGKYLASCVQYRLVVRDVNTLQILQLYTCLDQIQHIEWSADS 60
MNFSEVFKLSSLLCKFSPDGKYLASCVQYRLVVRDVNTLQILQLYTCLDQIQHIEWSADS
Sbjct: 1 MNFSEVFKLSSLLCKFSPDGKYLASCVQYRLVVRDVNTLQILQLYTCLDQIQHIEWSADS 60
Query: 61 LFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWS 120
LFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWS
Sbjct: 61 LFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWS 120
Query: 121 LCTKSVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRHFDTDTQD 180
LCTKSVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRHFDTDTQD
Sbjct: 121 LCTKSVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRHFDTDTQD 180
Query: 181 LTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSPSSQFLAV 240
LTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSPSSQFLAV
Sbjct: 181 LTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSPSSQFLAV 240
Query: 241 GSYDGKVRILNHVTWKMITEFGHPAAINDPKIVVYKEAEKSPQLGLGCLSFPPPRAGAGP 300
GSYDGKVRILNHVTWKMITEFGHPAAINDPKIVVYKEAEKSPQLGLGCLSFPPPRAGAGP
Sbjct: 241 GSYDGKVRILNHVTWKMITEFGHPAAINDPKIVVYKEAEKSPQLGLGCLSFPPPRAGAGP 300
Query: 301 LPSSESKYEIASVPVSLQTLKPVTDRANPKIGIGMLAFSPDSYFLATRNDNIPNAVWVWD 360
LPSSESKYEIASVPVSLQTLKPVTDRANPKIGIGMLAFSPDSYFLATRNDNIPNAVWVWD
Sbjct: 301 LPSSESKYEIASVPVSLQTLKPVTDRANPKIGIGMLAFSPDSYFLATRNDNIPNAVWVWD 360
Query: 361 IQKLRLFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSPAGCMSVQVPGEGDFAVLS 420
IQKLRLFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSPAGCMSVQVPGEGDFAVLS
Sbjct: 361 IQKLRLFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSPAGCMSVQVPGEGDFAVLS 420
Query: 421 LCWHLSGDSMALLSKDHFCLCFLETEAVVGTACRQLGGHT 460
LCWHLSGDSMALLSKDHFCLCFLETEAVVGTACRQLGGHT
Sbjct: 421 LCWHLSGDSMALLSKDHFCLCFLETEAVVGTACRQLGGHT 460
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 46.6 bits (109), Expect = 5e-05
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 25/269 (9%)
Query: 14 CKFSPDGKYLASCVQYRLV----VRDVNTLQILQLY-TCLDQIQHIEWSADSL----FIL 64
C FSP+ K LA+ L V D N L L+ + T + I S SL L
Sbjct: 237 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNL 296
Query: 65 CAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSL-CT 123
+ G V++WSL+ E I+ + + W P GR L TT + +W L
Sbjct: 297 ASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGR-FLGTTCYDRSWRLWDLEAQ 355
Query: 124 KSVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRHFDTDTQDLTG 183
+ + + + + I F +DG +LA + ++ + + + +++ G
Sbjct: 356 EEILHQEGHSMGVYDIAFHQDG---SLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYG 412
Query: 184 IEWAPNGCVLAVW---DTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSP-SSQFLA 239
I ++PNG +A +TC + + R + T A++ + V + P FL
Sbjct: 413 INFSPNGYHIATGSGDNTCKVWDL----RQRRCVYTIPAHQNL--VTGVKFEPIHGNFLL 466
Query: 240 VGSYDGKVRILNHVTWKMI-TEFGHPAAI 267
G+YD +I H W + T GH +
Sbjct: 467 TGAYDNTAKIWTHPGWSPLKTLAGHEGKV 495
Score = 29.3 bits (64), Expect = 7.8
Identities = 32/141 (22%), Positives = 46/141 (32%), Gaps = 21/141 (14%)
Query: 301 LPSSESKYEIASVPVSLQTLKPVTDRANPKIGIGMLAFSPDSYFLATRNDNIPNAVW--- 357
+P + ++ + SL++L + I FSP+S LAT A W
Sbjct: 202 IPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLAT-------ACWSGL 254
Query: 358 --VWDIQKLRLFAVLEQ---------LSPVRAFQWDPQQPRLAICTGGSRLYLWSPAGCM 406
+W + L L P DP+ LA C + LWS
Sbjct: 255 CKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDE 314
Query: 407 SVQVPGEGDFAVLSLCWHLSG 427
V V + WH SG
Sbjct: 315 PVADIEGHTVRVARVMWHPSG 335
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 45.1 bits (105), Expect = 1e-04
Identities = 69/320 (21%), Positives = 128/320 (40%), Gaps = 47/320 (14%)
Query: 16 FSPDGKYLASCVQYRLV------------VRDVNTLQILQLYTCLDQIQHIEWSADSLFI 63
FSP G LAS + + V V +T + ++ C D + S D
Sbjct: 31 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKT-- 88
Query: 64 LCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCT 123
V+VW+ + ++ + + + + +SPDGR I++ ++ + +W +
Sbjct: 89 ---------VKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD-DKTVKLWDKSS 138
Query: 124 KSV--SYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRHFDTDTQDL 181
+ SY ++ + + F G +A A + V ++ +LL+H+ + +
Sbjct: 139 RECVHSYCEH-GGFVTYVDFHPSGTCIAAA---GMDNTVKVWDVRTHRLLQHYQLHSAAV 194
Query: 182 TGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSPSSQFLAVG 241
G+ + P+G L + KI L ++GRLL T ++ +VA+S + ++ A G
Sbjct: 195 NGLSFHPSGNYLITASSDSTLKI-LDLMEGRLLYTLHGHQGP--ATTVAFSRTGEYFASG 251
Query: 242 SYDGKVRILNHVTWKM---ITEFGHPAAINDPKIVVYKEAEKSPQLGLGCLSFP-PPRAG 297
D +V + WK I + G + P + P+ + FP PP G
Sbjct: 252 GSDEQVMV-----WKSNFDIVDHGEVTKVPRPPATLASSMGNLPE-----VDFPVPPGRG 301
Query: 298 AGPLPSSESKYEIASVPVSL 317
E SVP +L
Sbjct: 302 RSVESVQSQPQEPVSVPQTL 321
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 45.1 bits (105), Expect = 1e-04
Identities = 69/320 (21%), Positives = 128/320 (40%), Gaps = 47/320 (14%)
Query: 16 FSPDGKYLASCVQYRLV------------VRDVNTLQILQLYTCLDQIQHIEWSADSLFI 63
FSP G LAS + + V V +T + ++ C D + S D
Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKT-- 126
Query: 64 LCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCT 123
V+VW+ + ++ + + + + +SPDGR I++ ++ + +W +
Sbjct: 127 ---------VKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD-DKTVKLWDKSS 176
Query: 124 KSV--SYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRHFDTDTQDL 181
+ SY ++ + + F G +A A + V ++ +LL+H+ + +
Sbjct: 177 RECVHSYCEH-GGFVTYVDFHPSGTCIAAA---GMDNTVKVWDVRTHRLLQHYQLHSAAV 232
Query: 182 TGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSPSSQFLAVG 241
G+ + P+G L + KI L ++GRLL T ++ +VA+S + ++ A G
Sbjct: 233 NGLSFHPSGNYLITASSDSTLKI-LDLMEGRLLYTLHGHQGP--ATTVAFSRTGEYFASG 289
Query: 242 SYDGKVRILNHVTWKM---ITEFGHPAAINDPKIVVYKEAEKSPQLGLGCLSFP-PPRAG 297
D +V + WK I + G + P + P+ + FP PP G
Sbjct: 290 GSDEQVMV-----WKSNFDIVDHGEVTKVPRPPATLASSMGNLPE-----VDFPVPPGRG 339
Query: 298 AGPLPSSESKYEIASVPVSL 317
E SVP +L
Sbjct: 340 RSVESVQSQPQEPVSVPQTL 359
>gi|31317278 WD repeat domain 20 isoform 3 [Homo sapiens]
Length = 508
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 51 IQHIEWSADSLFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTT 110
+ +S D F+ C + G ++V++ + E H + GL+ CWSPDG++I+
Sbjct: 162 LNEFAFSPDGKFLACVS-QDGFLRVFNFDSVELHGTMKSYFGGLLCVCWSPDGKYIVTGG 220
Query: 111 EFHLRITVWS 120
E L +TVWS
Sbjct: 221 EDDL-VTVWS 229
>gi|31317276 WD repeat domain 20 isoform 4 [Homo sapiens]
Length = 445
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 51 IQHIEWSADSLFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTT 110
+ +S D F+ C + G ++V++ + E H + GL+ CWSPDG++I+
Sbjct: 99 LNEFAFSPDGKFLACVS-QDGFLRVFNFDSVELHGTMKSYFGGLLCVCWSPDGKYIVTGG 157
Query: 111 EFHLRITVWS 120
E L +TVWS
Sbjct: 158 EDDL-VTVWS 166
>gi|31317274 WD repeat domain 20 isoform 1 [Homo sapiens]
Length = 581
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 51 IQHIEWSADSLFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTT 110
+ +S D F+ C + G ++V++ + E H + GL+ CWSPDG++I+
Sbjct: 223 LNEFAFSPDGKFLACVS-QDGFLRVFNFDSVELHGTMKSYFGGLLCVCWSPDGKYIVTGG 281
Query: 111 EFHLRITVWS 120
E L +TVWS
Sbjct: 282 EDDL-VTVWS 290
>gi|31317280 WD repeat domain 20 isoform 2 [Homo sapiens]
Length = 569
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 51 IQHIEWSADSLFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTT 110
+ +S D F+ C + G ++V++ + E H + GL+ CWSPDG++I+
Sbjct: 223 LNEFAFSPDGKFLACVS-QDGFLRVFNFDSVELHGTMKSYFGGLLCVCWSPDGKYIVTGG 281
Query: 111 EFHLRITVWS 120
E L +TVWS
Sbjct: 282 EDDL-VTVWS 290
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 43.5 bits (101), Expect = 4e-04
Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 333 IGMLAFSPDSYFLATRNDNIPNAVWVWDIQKLRLFAVLE-QLSPVRAFQWDPQQPRL-AI 390
+ ++ F P+ Y LA+ + + + WD++K ++ + +E + PVR+ ++P L +
Sbjct: 192 VNVVEFHPNEYLLASGSSD--RTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSG 249
Query: 391 CTGGSRLYLWSPAGCMSVQVPGEGDFAVLSLC 422
C R+Y W P C V + G A L++C
Sbjct: 250 CQDSLRVYGWEPERCFDVVLVNWGKVADLAIC 281
>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
sapiens]
Length = 769
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/199 (26%), Positives = 88/199 (44%), Gaps = 32/199 (16%)
Query: 70 RGLVQVWSLEQPEWHCKIDE----GSAGLVASC-WSPDGRHILNTTEFHLRITVWSLCTK 124
+G V++W + QP I + + SC PDGR ++ E +T+W L +
Sbjct: 503 KGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEAST-LTIWDLASP 561
Query: 125 SVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSD-----WQL-----LRHF 174
+ P+ + +T + Y ALA D K V CSD W L +R F
Sbjct: 562 T------PRIKAE-LTSSAPACY-ALAISPDAK--VCFSCCSDGNIAVWDLHNQTLVRQF 611
Query: 175 DTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSL-DGRLLSTYSAYEWSLGIKSVAWSP 233
T + I+ + +G L W L+ + + L +GR L + +++ I S+ + P
Sbjct: 612 QGHTDGASCIDISHDGTKL--WTGGLDNTVRSWDLREGRQLQQH---DFTSQIFSLGYCP 666
Query: 234 SSQFLAVGSYDGKVRILNH 252
+ ++LAVG V +L+H
Sbjct: 667 TGEWLAVGMESSNVEVLHH 685
>gi|157384984 transducin-like enhancer protein 3 isoform c [Homo
sapiens]
Length = 760
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/199 (26%), Positives = 88/199 (44%), Gaps = 32/199 (16%)
Query: 70 RGLVQVWSLEQPEWHCKIDE----GSAGLVASC-WSPDGRHILNTTEFHLRITVWSLCTK 124
+G V++W + QP I + + SC PDGR ++ E +T+W L +
Sbjct: 494 KGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEAST-LTIWDLASP 552
Query: 125 SVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSD-----WQL-----LRHF 174
+ P+ + +T + Y ALA D K V CSD W L +R F
Sbjct: 553 T------PRIKAE-LTSSAPACY-ALAISPDAK--VCFSCCSDGNIAVWDLHNQTLVRQF 602
Query: 175 DTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSL-DGRLLSTYSAYEWSLGIKSVAWSP 233
T + I+ + +G L W L+ + + L +GR L + +++ I S+ + P
Sbjct: 603 QGHTDGASCIDISHDGTKL--WTGGLDNTVRSWDLREGRQLQQH---DFTSQIFSLGYCP 657
Query: 234 SSQFLAVGSYDGKVRILNH 252
+ ++LAVG V +L+H
Sbjct: 658 TGEWLAVGMESSNVEVLHH 676
>gi|157384982 transducin-like enhancer protein 3 isoform a [Homo
sapiens]
Length = 772
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/199 (26%), Positives = 88/199 (44%), Gaps = 32/199 (16%)
Query: 70 RGLVQVWSLEQPEWHCKIDE----GSAGLVASC-WSPDGRHILNTTEFHLRITVWSLCTK 124
+G V++W + QP I + + SC PDGR ++ E +T+W L +
Sbjct: 506 KGCVKIWDISQPGSKSPISQLDCLNRDNYIRSCKLLPDGRTLIVGGEAST-LTIWDLASP 564
Query: 125 SVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSD-----WQL-----LRHF 174
+ P+ + +T + Y ALA D K V CSD W L +R F
Sbjct: 565 T------PRIKAE-LTSSAPACY-ALAISPDAK--VCFSCCSDGNIAVWDLHNQTLVRQF 614
Query: 175 DTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSL-DGRLLSTYSAYEWSLGIKSVAWSP 233
T + I+ + +G L W L+ + + L +GR L + +++ I S+ + P
Sbjct: 615 QGHTDGASCIDISHDGTKL--WTGGLDNTVRSWDLREGRQLQQH---DFTSQIFSLGYCP 669
Query: 234 SSQFLAVGSYDGKVRILNH 252
+ ++LAVG V +L+H
Sbjct: 670 TGEWLAVGMESSNVEVLHH 688
>gi|223005862 echinoderm microtubule associated protein like 6 [Homo
sapiens]
Length = 1958
Score = 40.4 bits (93), Expect = 0.003
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Query: 332 GIGMLAFSPDSYFLATRNDNIPNAVWVWDIQKLRLFAVLEQLSP-VRAFQWDPQQPRLAI 390
G+ LAF D LA+ + N V +WD +K +L A S + WDP QP +
Sbjct: 108 GVACLAFDSDGQRLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFDISWDPYQPNRVV 167
Query: 391 CTGGSRLYLWSPAG 404
G + W+ G
Sbjct: 168 SCGVKHIKFWTLCG 181
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 40.4 bits (93), Expect = 0.003
Identities = 53/248 (21%), Positives = 106/248 (42%), Gaps = 33/248 (13%)
Query: 16 FSPDGKYLASCVQYRLV------------VRDVNTLQILQLYTCLDQIQHIEWSADSLFI 63
FSP G LAS + + V V +T + ++ C D + S D
Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKT-- 126
Query: 64 LCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCT 123
V+VW+ + ++ + + + + +SPDGR I++ ++ + +W +
Sbjct: 127 ---------VKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASD-DKTVKLWDKSS 176
Query: 124 KSV--SYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRHFDTDTQDL 181
+ SY ++ + + F G +A A + V ++ +LL+H+ + +
Sbjct: 177 RECVHSYCEH-GGFVTYVDFHPSGTCIAAA---GMDNTVKVWDVRTHRLLQHYQLHSAAV 232
Query: 182 TGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSPSSQFLAVG 241
G+ + P+G L + KI L ++GRLL T ++ +VA+S + ++ A G
Sbjct: 233 NGLSFHPSGNYLITASSDSTLKI-LDLMEGRLLYTLHGHQGP--ATTVAFSRTGEYFASG 289
Query: 242 SYDGKVRI 249
D +V +
Sbjct: 290 GSDEQVMV 297
>gi|4757988 WD repeat domain 39 [Homo sapiens]
Length = 339
Score = 40.0 bits (92), Expect = 0.004
Identities = 47/206 (22%), Positives = 89/206 (43%), Gaps = 17/206 (8%)
Query: 54 IEWS-ADSLFILCAMYKRGLVQVWSLEQPEWHCK--IDEGSAGLVAS-CWSPDGRHILNT 109
+ W+ A +L C +R +++W E W CK + EG V WSP G ++ +
Sbjct: 22 LAWNPAGTLLASCGGDRR--IRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASA 79
Query: 110 TEFHLRITVWSLCT---KSVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCS 166
+ F +W + V+ ++ + ++ + + G +A R +
Sbjct: 80 S-FDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEED 138
Query: 167 DWQLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSL---DGRLLSTYSAYEWS 223
+++ + ++ TQD+ + W P+ +LA + + LY D +T +E +
Sbjct: 139 EYECVSVLNSHTQDVKHVVWHPSQELLA--SASYDDTVKLYREEEDDWVCCATLEGHEST 196
Query: 224 LGIKSVAWSPSSQFLAVGSYDGKVRI 249
+ S+A+ PS Q LA S D VRI
Sbjct: 197 --VWSLAFDPSGQRLASCSDDRTVRI 220
Score = 34.3 bits (77), Expect = 0.24
Identities = 32/130 (24%), Positives = 52/130 (40%), Gaps = 9/130 (6%)
Query: 336 LAFSPDSYFLATRNDNIPNAVWVWDIQKLRLFAVLE-QLSPVRAFQWDPQQPRLAICTGG 394
+A+SP +LA+ + + +W + LE + V++ W P LA C+
Sbjct: 67 VAWSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRD 126
Query: 395 SRLYLW-----SPAGCMSVQVPGEGDFAVLSLCWHLSGDSMALLSKDHFCLCFLETEAVV 449
+++W C+SV D V + WH S + +A S D + E E
Sbjct: 127 KSVWVWEVDEEDEYECVSVLNSHTQD--VKHVVWHPSQELLASASYDDTVKLYREEED-D 183
Query: 450 GTACRQLGGH 459
C L GH
Sbjct: 184 WVCCATLEGH 193
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 38.5 bits (88), Expect = 0.013
Identities = 59/258 (22%), Positives = 111/258 (43%), Gaps = 18/258 (6%)
Query: 15 KFSPDGKYLASCVQYRLVV--RDVNTLQILQLYTCLDQIQHIEWSADSLFILCAMYKRGL 72
KFSP+G++LAS RL++ + LY +I + WS+DS ++ A + L
Sbjct: 48 KFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTL 107
Query: 73 VQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSL----CTKSVSY 128
++W + + K +G + V C +++ + F + +W + C K++S
Sbjct: 108 -KLWDVRSGKC-LKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSA 165
Query: 129 IKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRHF-DTDTQDLTGIEWA 187
P + + F G +L I+ + Q L+ D D ++ ++++
Sbjct: 166 HSDP---VSAVHFNCSG---SLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFS 219
Query: 188 PNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWS-PSSQFLAVGSYDGK 246
PNG + K+ YS GR L TY+ ++ +S +++ GS D
Sbjct: 220 PNGKYILTATLDNTLKLWDYS-RGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNL 278
Query: 247 VRILNHVTWKMITEF-GH 263
V I N T +++ + GH
Sbjct: 279 VYIWNLQTKEIVQKLQGH 296
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 38.1 bits (87), Expect = 0.017
Identities = 45/221 (20%), Positives = 97/221 (43%), Gaps = 10/221 (4%)
Query: 49 DQIQHIEWSADSLFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILN 108
D + +++S + A R V++W ++ + +A + + +S DG+ +
Sbjct: 61 DVVTSVQFSPHGNLLASASRDR-TVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLAT 119
Query: 109 TTEFHLRITVWSLCTKSVSYIKYPKA-CLQGITFTRDGRYMALAERRDCKDYVSIFVCSD 167
+E I VWS+ + Y Y ++ F+ DGR + + I+ ++
Sbjct: 120 ASE-DKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKT---IKIWDTTN 175
Query: 168 WQLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIK 227
Q + +F +++ P+G +A + K+ ++ +LL Y + S G+
Sbjct: 176 KQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVN-KLLQHYQVH--SGGVN 232
Query: 228 SVAWSPSSQFLAVGSYDGKVRILNHVTWKMI-TEFGHPAAI 267
+++ PS +L S DG ++IL+ + ++I T GH +
Sbjct: 233 CISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPV 273
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 37.4 bits (85), Expect = 0.029
Identities = 57/260 (21%), Positives = 111/260 (42%), Gaps = 22/260 (8%)
Query: 15 KFSPDGKYLASCVQYRLVV-------RDVNTLQILQLYTCLDQIQHIEWSADSLFILCAM 67
KFSP+G++LAS +L+ + T+ +L I + WS+DS ++ A
Sbjct: 52 KFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKL-----GISDVAWSSDSNLLVSAS 106
Query: 68 YKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCT-KSV 126
+ L ++W + + K +G + V C +++ + F + +W + T K +
Sbjct: 107 DDKTL-KIWDVSSGKC-LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCL 164
Query: 127 SYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRH-FDTDTQDLTGIE 185
+ + + F RDG +L I+ + Q L+ D D ++ ++
Sbjct: 165 KTLPAHSDPVSAVHFNRDG---SLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK 221
Query: 186 WAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWS-PSSQFLAVGSYD 244
++PNG + K+ YS G+ L TY+ ++ +S +++ GS D
Sbjct: 222 FSPNGKYILAATLDNTLKLWDYS-KGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSED 280
Query: 245 GKVRILNHVTWKMITEF-GH 263
V I N T +++ + GH
Sbjct: 281 NLVYIWNLQTKEIVQKLQGH 300
Score = 34.7 bits (78), Expect = 0.19
Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 31/209 (14%)
Query: 178 TQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSPSSQF 237
T+ ++ ++++PNG LA KI + DG+ T S ++ LGI VAWS S
Sbjct: 45 TKAVSSVKFSPNGEWLASSSADKLIKIW-GAYDGKFEKTISGHK--LGISDVAWSSDSNL 101
Query: 238 LAVGSYDGKVRILNHVTWKMI-TEFGHPAAI------NDPKIVV---YKEAEKSPQLGLG 287
L S D ++I + + K + T GH + ++V + E+ + + G
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161
Query: 288 -CLSFPPPRAGA---------GPLPSSESKYEIASV--PVSLQTLKPVTDRANPKIGIGM 335
CL P + G L S S + + S Q LK + D NP +
Sbjct: 162 KCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP--VSF 219
Query: 336 LAFSPD-SYFLATRNDNIPNAVWVWDIQK 363
+ FSP+ Y LA D N + +WD K
Sbjct: 220 VKFSPNGKYILAATLD---NTLKLWDYSK 245
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 37.4 bits (85), Expect = 0.029
Identities = 57/260 (21%), Positives = 111/260 (42%), Gaps = 22/260 (8%)
Query: 15 KFSPDGKYLASCVQYRLVV-------RDVNTLQILQLYTCLDQIQHIEWSADSLFILCAM 67
KFSP+G++LAS +L+ + T+ +L I + WS+DS ++ A
Sbjct: 52 KFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKL-----GISDVAWSSDSNLLVSAS 106
Query: 68 YKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCT-KSV 126
+ L ++W + + K +G + V C +++ + F + +W + T K +
Sbjct: 107 DDKTL-KIWDVSSGKC-LKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCL 164
Query: 127 SYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRH-FDTDTQDLTGIE 185
+ + + F RDG +L I+ + Q L+ D D ++ ++
Sbjct: 165 KTLPAHSDPVSAVHFNRDG---SLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVK 221
Query: 186 WAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWS-PSSQFLAVGSYD 244
++PNG + K+ YS G+ L TY+ ++ +S +++ GS D
Sbjct: 222 FSPNGKYILAATLDNTLKLWDYS-KGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSED 280
Query: 245 GKVRILNHVTWKMITEF-GH 263
V I N T +++ + GH
Sbjct: 281 NLVYIWNLQTKEIVQKLQGH 300
Score = 34.7 bits (78), Expect = 0.19
Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 31/209 (14%)
Query: 178 TQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSPSSQF 237
T+ ++ ++++PNG LA KI + DG+ T S ++ LGI VAWS S
Sbjct: 45 TKAVSSVKFSPNGEWLASSSADKLIKIW-GAYDGKFEKTISGHK--LGISDVAWSSDSNL 101
Query: 238 LAVGSYDGKVRILNHVTWKMI-TEFGHPAAI------NDPKIVV---YKEAEKSPQLGLG 287
L S D ++I + + K + T GH + ++V + E+ + + G
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161
Query: 288 -CLSFPPPRAGA---------GPLPSSESKYEIASV--PVSLQTLKPVTDRANPKIGIGM 335
CL P + G L S S + + S Q LK + D NP +
Sbjct: 162 KCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP--VSF 219
Query: 336 LAFSPD-SYFLATRNDNIPNAVWVWDIQK 363
+ FSP+ Y LA D N + +WD K
Sbjct: 220 VKFSPNGKYILAATLD---NTLKLWDYSK 245
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 37.0 bits (84), Expect = 0.038
Identities = 62/298 (20%), Positives = 122/298 (40%), Gaps = 41/298 (13%)
Query: 14 CKFSPDGKYLASCVQYRLVV-----RDVNTLQILQLYTCLDQIQHIEWSADSLFILCAMY 68
CKF P+G LAS RL++ D + L+ ++ + + ++ D + A
Sbjct: 72 CKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHS--GAVMELHYNTDGSMLFSAST 129
Query: 69 KRGLVQVWSLEQPEWHCKIDEGSAGLVASCW-SPDGRHILNTTEFHLRITVWSLCTKSVS 127
+ V VW E E K +G V SC+ + G ++ T + +W +
Sbjct: 130 DK-TVAVWDSETGE-RVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDI------ 181
Query: 128 YIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSD---WQLLRHFDTDT-----Q 179
KA +Q TF + +A+ +S + +D W L ++ T T
Sbjct: 182 ---RKKAAIQ--TFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD 236
Query: 180 DLTGIEWAPNGCVL---AVWDTCLEYKILLYSLDGRLLSTY--SAYEWSLGIKSVAWSPS 234
+TG+ + G L A+ +T + + ++ R + + + + + + +WSP
Sbjct: 237 SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPD 296
Query: 235 SQFLAVGSYDGKVRILNHVTWKMITEF-GHPAAIN------DPKIVVYKEAEKSPQLG 285
+A GS D V + + + +++ + GH +IN D I++ ++K +G
Sbjct: 297 GSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMG 354
>gi|102470001 PQQ repeat and WD repeat domain containing [Homo
sapiens]
Length = 472
Score = 37.0 bits (84), Expect = 0.038
Identities = 29/147 (19%), Positives = 63/147 (42%), Gaps = 14/147 (9%)
Query: 14 CKFSPDGKYLAS--CVQYRLVVRD---VNTLQILQLYTCLDQIQHIEWSADSLFILCAMY 68
CKFSPDGKY+ S V + + + D + T+ +++ + I + DS +
Sbjct: 192 CKFSPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHH-TRSITSCCFDPDSQRVASVSL 250
Query: 69 KRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSL------- 121
R +++W + I + + +++C H L T+ + + +W++
Sbjct: 251 DR-CIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRN 309
Query: 122 CTKSVSYIKYPKACLQGITFTRDGRYM 148
C V+ ++ + + F RD ++
Sbjct: 310 CGACVTLMQGHEGSVSSCHFARDSSFL 336
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 37.0 bits (84), Expect = 0.038
Identities = 79/388 (20%), Positives = 133/388 (34%), Gaps = 88/388 (22%)
Query: 123 TKSVSYIKYPKACLQGITFTRDGRYMALAERR------DCKDYVSIFVCSDWQLLRHFDT 176
T+ S ++ + + F+ G+Y+A D F C RH+
Sbjct: 104 TRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGH---RHW-- 158
Query: 177 DTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLD-----GRLLSTYSAYEWSLGIKSVAW 231
+ I W+P+G LA C +ILL+ GR L+ +S + L + +
Sbjct: 159 ----VLSISWSPDGRKLA--SGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHA 212
Query: 232 SPSSQFLAVGSYDGKVR------------ILNHVTWKMITEFGHP----AAINDPKIVVY 275
+P +++A S DG VR + H +G +A D I V+
Sbjct: 213 NPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVW 272
Query: 276 KEAEK------------------SPQLGLGCLSFPPPRAGAGPLPSSESKYEIASVPVSL 317
+ + S L +F P A P S E+ +S
Sbjct: 273 RAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSR 332
Query: 318 QTL---------------------------KPVTDRANPKIGIGMLAFSPDSYFLATRND 350
L KP+T + I + FSPDS +A+
Sbjct: 333 YNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASA-- 390
Query: 351 NIPNAVWVWDIQKLRLFAVLE-QLSPVRAFQWDPQQPRLAICTGGSRLYLWS-PAGCMSV 408
+ ++ +WD + + A L ++ V W L + S L +W A +++
Sbjct: 391 SFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAM 450
Query: 409 QVPGEGDFAVLSLCWHLSGDSMALLSKD 436
+PG D V ++ W G +A KD
Sbjct: 451 DLPGHAD-EVYAVDWSPDGQRVASGGKD 477
Score = 30.4 bits (67), Expect = 3.5
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 16 FSPDGKYLASC-VQYRLVVRDVNTLQIL-QLYTCLDQIQHIEWSADSLFILCAMYKRGLV 73
FSPD + +AS + + D T + L L + + I WSADS ++ L
Sbjct: 380 FSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTL- 438
Query: 74 QVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHI 106
+VW ++ + + + + A WSPDG+ +
Sbjct: 439 KVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRV 471
>gi|209969680 Fzr1 protein isoform 1 [Homo sapiens]
Length = 496
Score = 36.6 bits (83), Expect = 0.049
Identities = 47/203 (23%), Positives = 80/203 (39%), Gaps = 32/203 (15%)
Query: 226 IKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEF-GHPAAINDPKIVVYKEAEKSPQL 284
+ SV WS +AVG++ G V+I + K ++ GH A +
Sbjct: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARV----------------- 274
Query: 285 GLGCLSFPPPRAGAGPLPSSESKYEIASVPVSLQTLKPVTDRANPKIGIGMLAFSPDSYF 344
G L++ + +G + +I + P LQ+ + + G L +S D
Sbjct: 275 --GALAWNAEQLSSGSRDRMILQRDIRTPP--LQSERRLQGHRQEVCG---LKWSTDHQL 327
Query: 345 LATRNDNIPNAVWVWDIQKLR-LFAVLEQLSPVRAFQWDPQQPRLAICTGGSR---LYLW 400
LA+ ++ N + VW+ L + E L+ V+A W P Q L GG+ + W
Sbjct: 328 LASGGND--NKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 385
Query: 401 SPAGCMSVQVPGEGDFAVLSLCW 423
+ +Q G V +L W
Sbjct: 386 NTLTGQPLQCIDTGS-QVCNLAW 407
>gi|209969678 Fzr1 protein isoform 3 [Homo sapiens]
Length = 404
Score = 36.6 bits (83), Expect = 0.049
Identities = 47/203 (23%), Positives = 80/203 (39%), Gaps = 32/203 (15%)
Query: 226 IKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEF-GHPAAINDPKIVVYKEAEKSPQL 284
+ SV WS +AVG++ G V+I + K ++ GH A +
Sbjct: 143 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARV----------------- 185
Query: 285 GLGCLSFPPPRAGAGPLPSSESKYEIASVPVSLQTLKPVTDRANPKIGIGMLAFSPDSYF 344
G L++ + +G + +I + P LQ+ + + G L +S D
Sbjct: 186 --GALAWNAEQLSSGSRDRMILQRDIRTPP--LQSERRLQGHRQEVCG---LKWSTDHQL 238
Query: 345 LATRNDNIPNAVWVWDIQKLR-LFAVLEQLSPVRAFQWDPQQPRLAICTGGSR---LYLW 400
LA+ ++ N + VW+ L + E L+ V+A W P Q L GG+ + W
Sbjct: 239 LASGGND--NKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 296
Query: 401 SPAGCMSVQVPGEGDFAVLSLCW 423
+ +Q G V +L W
Sbjct: 297 NTLTGQPLQCIDTGS-QVCNLAW 318
>gi|33620742 Fzr1 protein isoform 2 [Homo sapiens]
Length = 493
Score = 36.6 bits (83), Expect = 0.049
Identities = 47/203 (23%), Positives = 80/203 (39%), Gaps = 32/203 (15%)
Query: 226 IKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEF-GHPAAINDPKIVVYKEAEKSPQL 284
+ SV WS +AVG++ G V+I + K ++ GH A +
Sbjct: 232 VTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARV----------------- 274
Query: 285 GLGCLSFPPPRAGAGPLPSSESKYEIASVPVSLQTLKPVTDRANPKIGIGMLAFSPDSYF 344
G L++ + +G + +I + P LQ+ + + G L +S D
Sbjct: 275 --GALAWNAEQLSSGSRDRMILQRDIRTPP--LQSERRLQGHRQEVCG---LKWSTDHQL 327
Query: 345 LATRNDNIPNAVWVWDIQKLR-LFAVLEQLSPVRAFQWDPQQPRLAICTGGSR---LYLW 400
LA+ ++ N + VW+ L + E L+ V+A W P Q L GG+ + W
Sbjct: 328 LASGGND--NKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFW 385
Query: 401 SPAGCMSVQVPGEGDFAVLSLCW 423
+ +Q G V +L W
Sbjct: 386 NTLTGQPLQCIDTGS-QVCNLAW 407
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 36.6 bits (83), Expect = 0.049
Identities = 42/211 (19%), Positives = 81/211 (38%), Gaps = 24/211 (11%)
Query: 51 IQHIEWSADSLFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTT 110
+ ++W++D + Y G ++W+ E + + + A W+ G ++L+
Sbjct: 238 VTSLDWNSDGTLLAMGSYD-GFARIWT-ENGNLASTLGQHKGPIFALKWNKKGNYVLSAG 295
Query: 111 EFHLRITVWSLCT-KSVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDW- 168
I +W T ++ + A + + + + + C + I VC
Sbjct: 296 VDKTTI-IWDAHTGEAKQQFPFHSAPALDVDWQNNMTFAS------CSTDMCIHVCRLGC 348
Query: 169 -QLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIK 227
++ F T ++ I+W P+G +LA + KI D + S I
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDA---CVHDLQAHSKEIY 405
Query: 228 SVAWSP---------SSQFLAVGSYDGKVRI 249
++ WSP SS LA S+D VR+
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRL 436
Score = 31.6 bits (70), Expect = 1.6
Identities = 24/114 (21%), Positives = 53/114 (46%), Gaps = 8/114 (7%)
Query: 156 CKDYVSIFVCSDWQ--LLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRL 213
C D +++ + S Q + ++++ I+W+P G + ++ + + RL
Sbjct: 377 CSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRL 436
Query: 214 ------LSTYSAYEWSLGIKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEF 261
+ T++ + + SVA+SP ++LA GS+D V I N + ++ +
Sbjct: 437 WDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490
Score = 29.3 bits (64), Expect = 7.8
Identities = 17/85 (20%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 354 NAVWVWDIQK-LRLFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSP-AGCMSVQVP 411
+ V +WD+++ + +++ PV + + P LA + +++W+ +G +
Sbjct: 432 STVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQ 491
Query: 412 GEGDFAVLSLCWHLSGDSMALLSKD 436
G G + +CW+ GD + + D
Sbjct: 492 GTG--GIFEVCWNARGDKVGASASD 514
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 36.6 bits (83), Expect = 0.049
Identities = 42/211 (19%), Positives = 81/211 (38%), Gaps = 24/211 (11%)
Query: 51 IQHIEWSADSLFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTT 110
+ ++W++D + Y G ++W+ E + + + A W+ G ++L+
Sbjct: 238 VTSLDWNSDGTLLAMGSYD-GFARIWT-ENGNLASTLGQHKGPIFALKWNKKGNYVLSAG 295
Query: 111 EFHLRITVWSLCT-KSVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDW- 168
I +W T ++ + A + + + + + C + I VC
Sbjct: 296 VDKTTI-IWDAHTGEAKQQFPFHSAPALDVDWQNNMTFAS------CSTDMCIHVCRLGC 348
Query: 169 -QLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIK 227
++ F T ++ I+W P+G +LA + KI D + S I
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDA---CVHDLQAHSKEIY 405
Query: 228 SVAWSP---------SSQFLAVGSYDGKVRI 249
++ WSP SS LA S+D VR+
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRL 436
Score = 31.6 bits (70), Expect = 1.6
Identities = 24/114 (21%), Positives = 53/114 (46%), Gaps = 8/114 (7%)
Query: 156 CKDYVSIFVCSDWQ--LLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRL 213
C D +++ + S Q + ++++ I+W+P G + ++ + + RL
Sbjct: 377 CSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRL 436
Query: 214 ------LSTYSAYEWSLGIKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEF 261
+ T++ + + SVA+SP ++LA GS+D V I N + ++ +
Sbjct: 437 WDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490
Score = 29.3 bits (64), Expect = 7.8
Identities = 17/85 (20%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 354 NAVWVWDIQK-LRLFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSP-AGCMSVQVP 411
+ V +WD+++ + +++ PV + + P LA + +++W+ +G +
Sbjct: 432 STVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQ 491
Query: 412 GEGDFAVLSLCWHLSGDSMALLSKD 436
G G + +CW+ GD + + D
Sbjct: 492 GTG--GIFEVCWNARGDKVGASASD 514
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 36.6 bits (83), Expect = 0.049
Identities = 42/211 (19%), Positives = 81/211 (38%), Gaps = 24/211 (11%)
Query: 51 IQHIEWSADSLFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTT 110
+ ++W++D + Y G ++W+ E + + + A W+ G ++L+
Sbjct: 238 VTSLDWNSDGTLLAMGSYD-GFARIWT-ENGNLASTLGQHKGPIFALKWNKKGNYVLSAG 295
Query: 111 EFHLRITVWSLCT-KSVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDW- 168
I +W T ++ + A + + + + + C + I VC
Sbjct: 296 VDKTTI-IWDAHTGEAKQQFPFHSAPALDVDWQNNMTFAS------CSTDMCIHVCRLGC 348
Query: 169 -QLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIK 227
++ F T ++ I+W P+G +LA + KI D + S I
Sbjct: 349 DHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDA---CVHDLQAHSKEIY 405
Query: 228 SVAWSP---------SSQFLAVGSYDGKVRI 249
++ WSP SS LA S+D VR+
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRL 436
Score = 31.6 bits (70), Expect = 1.6
Identities = 24/114 (21%), Positives = 53/114 (46%), Gaps = 8/114 (7%)
Query: 156 CKDYVSIFVCSDWQ--LLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRL 213
C D +++ + S Q + ++++ I+W+P G + ++ + + RL
Sbjct: 377 CSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRL 436
Query: 214 ------LSTYSAYEWSLGIKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEF 261
+ T++ + + SVA+SP ++LA GS+D V I N + ++ +
Sbjct: 437 WDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490
Score = 29.3 bits (64), Expect = 7.8
Identities = 17/85 (20%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 354 NAVWVWDIQK-LRLFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSP-AGCMSVQVP 411
+ V +WD+++ + +++ PV + + P LA + +++W+ +G +
Sbjct: 432 STVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQ 491
Query: 412 GEGDFAVLSLCWHLSGDSMALLSKD 436
G G + +CW+ GD + + D
Sbjct: 492 GTG--GIFEVCWNARGDKVGASASD 514
>gi|147904340 WD repeat domain 82 [Homo sapiens]
Length = 313
Score = 36.2 bits (82), Expect = 0.064
Identities = 20/75 (26%), Positives = 43/75 (57%), Gaps = 2/75 (2%)
Query: 178 TQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIK-SVAWSPSSQ 236
T + TG++++ +G ++ + T + L+ + G ++ T+ Y S + +++P SQ
Sbjct: 194 TCEWTGLKFSNDGKLILI-STNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQ 252
Query: 237 FLAVGSYDGKVRILN 251
F+ +GS DGK+ + N
Sbjct: 253 FIMIGSEDGKIHVWN 267
>gi|145279222 WD repeat domain 66 [Homo sapiens]
Length = 1149
Score = 36.2 bits (82), Expect = 0.064
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 71 GLVQVWSLEQPEW-HCKIDEGSAGLVASCWSPDGRHI-LNTTEFHLRIT-VWSLCTKSVS 127
G+++VW+ E ++ ++ E G+ + ++P+G + TE + I SL +S
Sbjct: 628 GMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTVYILDAMSLENESPE 687
Query: 128 YIKYPKACLQGITFTRDGRYMALAER 153
KY + + I+F+ D +YMA A+R
Sbjct: 688 PFKYSRTSVTHISFSHDSQYMATADR 713
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,597,497
Number of Sequences: 37866
Number of extensions: 934140
Number of successful extensions: 2761
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 2471
Number of HSP's gapped (non-prelim): 355
length of query: 460
length of database: 18,247,518
effective HSP length: 106
effective length of query: 354
effective length of database: 14,233,722
effective search space: 5038737588
effective search space used: 5038737588
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.