Guide to the Human Genome
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Search of human proteins with 224282125

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224282125 tRNA-yW synthesizing protein 1 homolog B isoform 2
[Homo sapiens]
         (471 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224282125 tRNA-yW synthesizing protein 1 homolog B isoform 2 ...   967   0.0  
gi|224282123 tRNA-yW synthesizing protein 1 homolog B isoform 1 ...   733   0.0  
gi|50726981 radical S-adenosyl methionine and flavodoxin domains...   671   0.0  
gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]            37   0.030
gi|21361517 UBX domain protein 1 [Homo sapiens]                        37   0.039
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    36   0.086
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    35   0.11 
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    34   0.33 
gi|28274705 family with sequence similarity 9, member A [Homo sa...    34   0.33 
gi|4826724 zygin 1 isoform 1 [Homo sapiens]                            33   0.43 
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]                       33   0.56 
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]                       33   0.56 
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    33   0.56 
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    33   0.56 
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    33   0.56 
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    33   0.73 
gi|6005757 chromatin-specific transcription elongation factor la...    32   0.95 
gi|33391150 nucleoplasmin 2 [Homo sapiens]                             32   0.95 
gi|21735569 claspin [Homo sapiens]                                     32   1.2  
gi|24307965 UBX domain containing 2 [Homo sapiens]                     32   1.2  
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    32   1.2  
gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein...    32   1.2  
gi|221219020 NYD-SP11 protein [Homo sapiens]                           32   1.6  
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    32   1.6  
gi|215422388 death-domain associated protein isoform a [Homo sap...    32   1.6  
gi|215422366 death-domain associated protein isoform b [Homo sap...    32   1.6  
gi|222136585 timeless homolog [Homo sapiens]                           32   1.6  
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...    32   1.6  
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...    32   1.6  
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            32   1.6  

>gi|224282125 tRNA-yW synthesizing protein 1 homolog B isoform 2
           [Homo sapiens]
          Length = 471

 Score =  967 bits (2500), Expect = 0.0
 Identities = 471/471 (100%), Positives = 471/471 (100%)

Query: 1   MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL 60
           MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL
Sbjct: 1   MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL 60

Query: 61  PVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 120
           PVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK
Sbjct: 61  PVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEK 120

Query: 121 REKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHR 180
           REKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHR
Sbjct: 121 REKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHR 180

Query: 181 CMETTPSLACANKCVFCWWHHNNPVGTEWWWKMDQPEMILKEAIENHQNMIKQFKGVPGV 240
           CMETTPSLACANKCVFCWWHHNNPVGTEWWWKMDQPEMILKEAIENHQNMIKQFKGVPGV
Sbjct: 181 CMETTPSLACANKCVFCWWHHNNPVGTEWWWKMDQPEMILKEAIENHQNMIKQFKGVPGV 240

Query: 241 KAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPV 300
           KAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPV
Sbjct: 241 KAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPV 300

Query: 301 TQLYVSVDASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQ 360
           TQLYVSVDASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQ
Sbjct: 301 TQLYVSVDASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQ 360

Query: 361 AYAQLVSLGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACE 420
           AYAQLVSLGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACE
Sbjct: 361 AYAQLVSLGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACE 420

Query: 421 HEHSNCLLIAHRKTVLGGTPGHGVTEIQWEEWIKKRLISQARWLMSVIPAH 471
           HEHSNCLLIAHRKTVLGGTPGHGVTEIQWEEWIKKRLISQARWLMSVIPAH
Sbjct: 421 HEHSNCLLIAHRKTVLGGTPGHGVTEIQWEEWIKKRLISQARWLMSVIPAH 471


>gi|224282123 tRNA-yW synthesizing protein 1 homolog B isoform 1
           [Homo sapiens]
          Length = 668

 Score =  733 bits (1892), Expect = 0.0
 Identities = 361/386 (93%), Positives = 365/386 (94%), Gaps = 9/386 (2%)

Query: 68  KEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQE 127
           +E D   H   +EEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQE
Sbjct: 230 QEQDELHHRDTKEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQE 289

Query: 128 EKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPS 187
           EKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPS
Sbjct: 290 EKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHRCMETTPS 349

Query: 188 LACANKCVFCWWHHNNPVGTEWWWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEE 247
           LACANKCVFCWWHHNNPVGTEW WKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEE
Sbjct: 350 LACANKCVFCWWHHNNPVGTEWLWKMDQPEMILKEAIENHQNMIKQFKGVPGVKAERFEE 409

Query: 248 GMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSV 307
           GMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSV
Sbjct: 410 GMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQFPAEIRNLEPVTQLYVSV 469

Query: 308 DASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVS 367
           DASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVS
Sbjct: 470 DASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTLVKAWNVDELQAYAQLVS 529

Query: 368 LGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCL 427
           LGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCL
Sbjct: 530 LGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVDLIPEYEIACEHEHSNCL 589

Query: 428 LIAHRKTVLGGTPGHGVTEIQWEEWI 453
           LIAHRK  +GG         +W  WI
Sbjct: 590 LIAHRKFKIGG---------EWWTWI 606



 Score =  162 bits (409), Expect = 8e-40
 Identities = 79/79 (100%), Positives = 79/79 (100%)

Query: 1  MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL 60
          MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL
Sbjct: 1  MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQGFATVLAEAVTSLDL 60

Query: 61 PVAIINLKEYDPDDHLIEE 79
          PVAIINLKEYDPDDHLIEE
Sbjct: 61 PVAIINLKEYDPDDHLIEE 79


>gi|50726981 radical S-adenosyl methionine and flavodoxin domains 1
           [Homo sapiens]
          Length = 732

 Score =  671 bits (1731), Expect = 0.0
 Identities = 343/403 (85%), Positives = 347/403 (86%), Gaps = 27/403 (6%)

Query: 69  EYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEE 128
           E D   H   EEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEE
Sbjct: 277 EQDELHHRDTEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEE 336

Query: 129 KSGLFRNMGRNEDGERRAMITPALREALTKQ-----------------VDAPRERSLLQT 171
           KSGLFRNMGRNEDGERRAMITPALREALTKQ                     R R     
Sbjct: 337 KSGLFRNMGRNEDGERRAMITPALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYK 396

Query: 172 HILWN-ESHRCMETTPSLACANKCVFCWWHHNNPVGTEWWWKMDQPEMILKEAIENHQNM 230
           H  +  ESHRCMETTPSLACANKCVFCW HH NPVGTEW WKMDQPEMILKEAIENHQNM
Sbjct: 397 HTFYGIESHRCMETTPSLACANKCVFCWRHHTNPVGTEWRWKMDQPEMILKEAIENHQNM 456

Query: 231 IKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQF 290
           IKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQF
Sbjct: 457 IKQFKGVPGVKAERFEEGMTVKHCALSLVGEPIMYPEINRFLKLLHQCKISSFLVTNAQF 516

Query: 291 PAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQQFLDSLKALAVKQQRTVYRLTL 350
           PAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQ+FLDSLKALAVKQQRTVYRLTL
Sbjct: 517 PAEIRNLEPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLKALAVKQQRTVYRLTL 576

Query: 351 VKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCRESSASSLTMAHVPWHEEVVQFVRELVD 410
           VKAWNVDELQAYAQLVSLGNPDFIEVKGVTYC ESSASSLTMAHVPWHEEVVQFV ELVD
Sbjct: 577 VKAWNVDELQAYAQLVSLGNPDFIEVKGVTYCGESSASSLTMAHVPWHEEVVQFVHELVD 636

Query: 411 LIPEYEIACEHEHSNCLLIAHRKTVLGGTPGHGVTEIQWEEWI 453
           LIPEYEIACEHEHSNCLLIAHRK  +GG         +W  WI
Sbjct: 637 LIPEYEIACEHEHSNCLLIAHRKFKIGG---------EWWTWI 670



 Score =  134 bits (336), Expect = 2e-31
 Identities = 76/125 (60%), Positives = 77/125 (61%), Gaps = 46/125 (36%)

Query: 1   MDPSADTWDLSSPLISLWINRFYIYLGFAVSISLWICVQIVIEMQ--------------- 45
           MDPSADTWDL SPLISLWINRFYIYLGFAVSISLWICVQIVI+ Q               
Sbjct: 1   MDPSADTWDLFSPLISLWINRFYIYLGFAVSISLWICVQIVIKTQGKNLQEKSVPKAAQD 60

Query: 46  -------------------------------GFATVLAEAVTSLDLPVAIINLKEYDPDD 74
                                          GFATVLAEAVTSLDLPVAIINLKEYDPDD
Sbjct: 61  LMTNGYVSLQEKDIFVSGVKIFYGSQTGTAKGFATVLAEAVTSLDLPVAIINLKEYDPDD 120

Query: 75  HLIEE 79
           HLIEE
Sbjct: 121 HLIEE 125


>gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]
          Length = 1720

 Score = 37.4 bits (85), Expect = 0.030
 Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 21/98 (21%)

Query: 78   EEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMG 137
            +EEE  +ES  EEE  GE++       D ED+ +  +  ++  R+ ++Q+E+ GL    G
Sbjct: 1421 QEEEVDYESEEEEEREGEEN-------DDEDMQEERNPHREGARKTQEQDEEVGL----G 1469

Query: 138  RNEDGERRAMIT----------PALREALTKQVDAPRE 165
              ED    A++T          P   EA+ ++V A RE
Sbjct: 1470 TEEDPSLPALLTQPRKPTHSQEPQGPEAMERRVQAVRE 1507


>gi|21361517 UBX domain protein 1 [Homo sapiens]
          Length = 312

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 37/147 (25%), Positives = 66/147 (44%), Gaps = 19/147 (12%)

Query: 38  VQIVIEMQGFATVLAEAVTSLD----LPVAIINLKEYDPDDHLIEEEEEPF------ESS 87
           ++ +IEM GF    AE   +L     +  A+  L E++ D  + E  E P       E +
Sbjct: 7   LESLIEM-GFPRGRAEKALALTGNQGIEAAMDWLMEHEDDPDVDEPLETPLGHILGREPT 65

Query: 88  SEEEFG--------GEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRN 139
           S E+ G        GE   +L+     E   ++++ V +++RE+E++EE+  L R   R 
Sbjct: 66  SSEQGGLEGSGSAAGEGKPALSEEERQEQTKRMLELVAQKQREREEREEREALERERQRR 125

Query: 140 EDGERRAMITPALREALTKQVDAPRER 166
             G+  +     L+E   ++    R R
Sbjct: 126 RQGQELSAARQRLQEDEMRRAAEERRR 152


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 35.8 bits (81), Expect = 0.086
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 9/88 (10%)

Query: 57  SLDLPVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHV 116
           +L+  + +IN+   D ++   EEEEE  E   EEE   E+ +        ED  +  +  
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE--------EDEEEYFEEE 924

Query: 117 KKEKREKEQQ-EEKSGLFRNMGRNEDGE 143
           ++E+ E E++ EE+ G        ED E
Sbjct: 925 EEEEEEFEEEFEEEEGELEEEEEEEDEE 952



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 36/159 (22%), Positives = 65/159 (40%), Gaps = 15/159 (9%)

Query: 46   GFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEEEEP-----FESSSEEEFGGEDHQSL 100
            G    L E +T +++  +    +E + ++   EEEEE       E   EEE+  E+ +  
Sbjct: 869  GGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE 928

Query: 101  NSIVD--VEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTK 158
                +   E+ G++ +  ++E  E+E++ E+           + E  A   P L  AL  
Sbjct: 929  EEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPP 988

Query: 159  QVDAPRERS--------LLQTHILWNESHRCMETTPSLA 189
                P+ +         LL+      E  R  +T P+LA
Sbjct: 989  PESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLA 1027


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 10/78 (12%)

Query: 68  KEYDPDDHLIEEEEEPFESSS--EEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQ 125
           +EYD D  ++E+EE+  E     EE+  GE+ +      D E        V  E+ E+E 
Sbjct: 177 EEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGE--------VDDEEDEEEL 228

Query: 126 QEEKSGLFRNMGRNEDGE 143
            EE+ G  R     ++GE
Sbjct: 229 GEEERGQKRKREPEDEGE 246


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 8/70 (11%)

Query: 65  INLKEYDPDDHLIEEEEEPFESSSEEEF------GGEDHQSLNSIVDVEDLGKIMDHVKK 118
           I +KE   ++   EEEEE  E S EEE       G E  +    + D +D GK +D  KK
Sbjct: 525 IEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLD--KK 582

Query: 119 EKREKEQQEE 128
             +E     E
Sbjct: 583 PSKEMSSDSE 592



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 26/120 (21%), Positives = 53/120 (44%), Gaps = 7/120 (5%)

Query: 68  KEYDPDDHLIEEEEEPFESSSEEEFGG--EDHQSLNSIVDVEDLGKIMDHVKKEKREKEQ 125
           K+  P    ++  +E      EEE     E+ + +  + ++E   K  + +++EKRE+++
Sbjct: 332 KKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKK 391

Query: 126 QEEKSGLFR-----NMGRNEDGERRAMITPALREALTKQVDAPRERSLLQTHILWNESHR 180
           Q+EK    R      +      E RA     L+    + V+ P + SL +   ++ +  R
Sbjct: 392 QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKR 451



 Score = 30.0 bits (66), Expect = 4.7
 Identities = 17/77 (22%), Positives = 39/77 (50%)

Query: 53  EAVTSLDLPVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKI 112
           E   S++L  A+  +++  P+        EP E    E+ G +D +++ S  + E +   
Sbjct: 462 EVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGN 521

Query: 113 MDHVKKEKREKEQQEEK 129
             H++ ++  +E++EE+
Sbjct: 522 KVHIEVKENPEEEEEEE 538


>gi|28274705 family with sequence similarity 9, member A [Homo
           sapiens]
          Length = 332

 Score = 33.9 bits (76), Expect = 0.33
 Identities = 24/90 (26%), Positives = 47/90 (52%), Gaps = 8/90 (8%)

Query: 48  ATVLAEAVTSLDLPVA---IINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIV 104
           A   AEA  + +   A   +I +++ + ++   EEE+E  E   EEE GGE+ +      
Sbjct: 197 AAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGG 256

Query: 105 DVEDLGKIMDHVKKEKREKEQQEEKSGLFR 134
           + E+  +     ++E+ E+E++EE+   F+
Sbjct: 257 EGEETEE-----EEEEEEEEEEEEQIKAFQ 281


>gi|4826724 zygin 1 isoform 1 [Homo sapiens]
          Length = 392

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 17/59 (28%), Positives = 31/59 (52%)

Query: 73  DDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSG 131
           D  + E+EEE F   SE + G  +   L +   +E++ ++M +    + E+E  EE+ G
Sbjct: 135 DTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDG 193


>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
          Length = 558

 Score = 33.1 bits (74), Expect = 0.56
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 6/109 (5%)

Query: 55  VTSLDLPVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMD 114
           +T   L +    ++    ++   E+EE+    S +E +  E+ +++       D     +
Sbjct: 119 ITDASLSLPSRRMQNDTAENETTEKEEK--SESRQERYEIEETETVTKSYQKNDWRDAEE 176

Query: 115 HVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAP 163
           + KKE +EKE++EE+     ++G N+ GE +     A RE L  Q D P
Sbjct: 177 N-KKEDKEKEEEEEEKPKRGSIGENQ-GEEKGTKVQAKREKL--QEDKP 221


>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
          Length = 564

 Score = 33.1 bits (74), Expect = 0.56
 Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 6/109 (5%)

Query: 55  VTSLDLPVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMD 114
           +T   L +    ++    ++   E+EE+    S +E +  E+ +++       D     +
Sbjct: 125 ITDASLSLPSRRMQNDTAENETTEKEEK--SESRQERYEIEETETVTKSYQKNDWRDAEE 182

Query: 115 HVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAP 163
           + KKE +EKE++EE+     ++G N+ GE +     A RE L  Q D P
Sbjct: 183 N-KKEDKEKEEEEEEKPKRGSIGENQ-GEEKGTKVQAKREKL--QEDKP 227


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 33.1 bits (74), Expect = 0.56
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 6/71 (8%)

Query: 78  EEEEEPFESSSEEEFG-----GEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGL 132
           EEEE+  E   E+E G     GE+   L+ ++  E   +  D    E+ E+E++EE+ GL
Sbjct: 191 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 250

Query: 133 FRNMGRNEDGE 143
            R   R  D E
Sbjct: 251 -RGEKRKRDAE 260


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score = 33.1 bits (74), Expect = 0.56
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 6/71 (8%)

Query: 78  EEEEEPFESSSEEEFG-----GEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGL 132
           EEEE+  E   E+E G     GE+   L+ ++  E   +  D    E+ E+E++EE+ GL
Sbjct: 150 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 209

Query: 133 FRNMGRNEDGE 143
            R   R  D E
Sbjct: 210 -RGEKRKRDAE 219


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score = 33.1 bits (74), Expect = 0.56
 Identities = 24/71 (33%), Positives = 36/71 (50%), Gaps = 6/71 (8%)

Query: 78  EEEEEPFESSSEEEFG-----GEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGL 132
           EEEE+  E   E+E G     GE+   L+ ++  E   +  D    E+ E+E++EE+ GL
Sbjct: 143 EEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGL 202

Query: 133 FRNMGRNEDGE 143
            R   R  D E
Sbjct: 203 -RGEKRKRDAE 212


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 32.7 bits (73), Expect = 0.73
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 16/96 (16%)

Query: 59  DLPVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKK 118
           D    +  + E + D+   +EE+E  E   EEEF  ED +  +   D +D     D V +
Sbjct: 157 DSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDD-----DEVSE 211

Query: 119 EKRE-----------KEQQEEKSGLFRNMGRNEDGE 143
           E+ E           ++++EE+ G      R  D E
Sbjct: 212 EEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDE 247


>gi|6005757 chromatin-specific transcription elongation factor large
            subunit [Homo sapiens]
          Length = 1047

 Score = 32.3 bits (72), Expect = 0.95
 Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 6/69 (8%)

Query: 73   DDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQ---EEK 129
            DD+  EEE+   + SSE E   E   S  S+   E+ GK  D +++E R+ +++   EE+
Sbjct: 953  DDYEEEEEDSDEDYSSEAE---ESDYSKESLGSEEESGKDWDELEEEARKADRESRYEEE 1009

Query: 130  SGLFRNMGR 138
                R+M R
Sbjct: 1010 EEQSRSMSR 1018


>gi|33391150 nucleoplasmin 2 [Homo sapiens]
          Length = 214

 Score = 32.3 bits (72), Expect = 0.95
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 13/83 (15%)

Query: 61  PVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLG---------- 110
           PV +   + Y+  D   EEEEE  E   EEE   ED +  ++ + +E+            
Sbjct: 112 PVFLSGQERYEASDLTWEEEEE--EEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVP 169

Query: 111 -KIMDHVKKEKREKEQQEEKSGL 132
            K     KK+K EKE++E ++ +
Sbjct: 170 QKQASVAKKKKLEKEEEEIRASV 192


>gi|21735569 claspin [Homo sapiens]
          Length = 1339

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 10/65 (15%)

Query: 67  LKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQ 126
           L + D +D   EEEEE  E + E E  GE+       V+ E+  + ++    E+ EKE++
Sbjct: 619 LFKLDNEDGFEEEEEEEEEMTDESEEDGEEK------VEKEEKEEELE----EEEEKEEE 668

Query: 127 EEKSG 131
           EE+ G
Sbjct: 669 EEEEG 673


>gi|24307965 UBX domain containing 2 [Homo sapiens]
          Length = 508

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 86  SSSEEEFGGEDHQSLNSI-VDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGER 144
           +SS+E  G  D +    + + VE L K ++  ++EKR++E+Q E   + + + R + G+ 
Sbjct: 178 TSSQEPSGCSDQRPAEDLNIRVERLTKKLEERREEKRKEEEQRE---IKKEIERRKTGKE 234

Query: 145 RAMITPALREALTKQVDAPRER 166
                    E LTK++   R R
Sbjct: 235 MLDYKRKQEEELTKRMLEERNR 256


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 26/76 (34%), Positives = 33/76 (43%), Gaps = 9/76 (11%)

Query: 72   PDDHLI----EEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQE 127
            P+D LI    EEEEE  E   EEE  GE+ +   ++    D  K      +EK E E   
Sbjct: 1343 PEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAK-----SQEKEEPEIST 1397

Query: 128  EKSGLFRNMGRNEDGE 143
            EK    R     E+ E
Sbjct: 1398 EKEDSARLDDHEEEEE 1413



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 23/111 (20%)

Query: 67   LKEYDPDDHLIEEEEEPFESSSEEEFGG------------EDHQSLNSIVDVEDLGKIMD 114
            +K  + ++   EEEEE  E   EEE GG            ++ +      + ED  ++ D
Sbjct: 1348 IKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDD 1407

Query: 115  HVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQVDAPRE 165
            H    + E+E+ EE S        NED +        +  A  ++ + PRE
Sbjct: 1408 H----EEEEEEDEEPS-------HNEDHDADDEDDSHMESAEVEKEELPRE 1447


>gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein
           [Homo sapiens]
          Length = 614

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 12/135 (8%)

Query: 50  VLAEAVTSLDLPVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGEDH----------QS 99
           +L   V  LD  V+ ++L+ ++ +D +  ++ E      E E                Q 
Sbjct: 348 ILKSHVEKLDNQVSKVHLEGFNDEDVISRQDHEQETEKLELEIQQCKEMIKTQQQLLQQQ 407

Query: 100 LNSIVDVEDLGKIMDHVKKEKREKEQQEEKSGLFRNMGRNEDGERRAMITPALREALTKQ 159
           L +  D +    + D    E  EKE+ +E+  LF+   +N + ERR+    A+R  L ++
Sbjct: 408 LATAYDDDTTSLLRDCYLLE--EKERLKEEWSLFKEQKKNFERERRSFTEAAIRLGLERK 465

Query: 160 VDAPRERSLLQTHIL 174
                  S L+   L
Sbjct: 466 AFEEERASWLKQQFL 480


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 66   NLKEYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQ 125
            +L   + ++   EEE E  E   EEE   E+ +     V+ E+  K     KK++++KE+
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK---KKKKKEKKKEE 2298

Query: 126  QEEKSGLFRNMGRNEDGERRAMITPALRE----ALTKQVDAPRERSLLQ 170
             +EK  +F         E    ++    E    +L ++VD  RE+ +L+
Sbjct: 2299 VQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVD--REKEILK 2345


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 16/77 (20%)

Query: 71  DPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKS 130
           D DD   +EEEE  E   EEE    + +        EDL ++ +  + ++ E E++E  +
Sbjct: 437 DEDDEESDEEEEEEEEEEEEEATDSEEE--------EDLEQMQEGQEDDEEEDEEEEAAA 488

Query: 131 GLFRNMGRNEDGERRAM 147
           G        +DG++  M
Sbjct: 489 G--------KDGDKSPM 497


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 16/77 (20%)

Query: 71  DPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKS 130
           D DD   +EEEE  E   EEE    + +        EDL ++ +  + ++ E E++E  +
Sbjct: 437 DEDDEESDEEEEEEEEEEEEEATDSEEE--------EDLEQMQEGQEDDEEEDEEEEAAA 488

Query: 131 GLFRNMGRNEDGERRAM 147
           G        +DG++  M
Sbjct: 489 G--------KDGDKSPM 497


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 16/77 (20%)

Query: 71  DPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKS 130
           D DD   +EEEE  E   EEE    + +        EDL ++ +  + ++ E E++E  +
Sbjct: 449 DEDDEESDEEEEEEEEEEEEEATDSEEE--------EDLEQMQEGQEDDEEEDEEEEAAA 500

Query: 131 GLFRNMGRNEDGERRAM 147
           G        +DG++  M
Sbjct: 501 G--------KDGDKSPM 509


>gi|222136585 timeless homolog [Homo sapiens]
          Length = 1208

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 36   ICVQIVIEMQGFATVLAEAVTSLDLPVAIINLKEYDPDDHLIEEEEEPFESSSEEEFGGE 95
            + + +V E +       + + S  LP    +LK++  +D L EEE  P E S EEE GG 
Sbjct: 932  LALGLVAERRELYKKRQKKLASSILPNGAESLKDFCQED-LEEEENLPEEDSEEEEEGGS 990

Query: 96   DHQSLNS--IVDVEDLGK 111
            + + +    ++  E+LG+
Sbjct: 991  EAEQVQGSLVLSNENLGQ 1008


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 69  EYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEE 128
           E D ++   EEEE   E   +E+  G+D +   S  + E+ G   D    E  +++++EE
Sbjct: 197 EKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVS-EEEEEFGLDKDE-DDEDEDEDEEEE 254

Query: 129 KSGLFRNMGRNEDGE 143
           +SG   N  R  D E
Sbjct: 255 ESGKGENRKRETDDE 269


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 69  EYDPDDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEE 128
           E D ++   EEEE   E   +E+  G+D +   S  + E+ G   D    E  +++++EE
Sbjct: 197 EKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVS-EEEEEFGLDKDE-DDEDEDEDEEEE 254

Query: 129 KSGLFRNMGRNEDGE 143
           +SG   N  R  D E
Sbjct: 255 ESGKGENRKRETDDE 269


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 14/59 (23%)

Query: 73  DDHLIEEEEEPFESSSEEEFGGEDHQSLNSIVDVEDLGKIMDHVKKEKREKEQQEEKSG 131
           ++  +EEEEE  E   +EE   ED +               +  ++EK E E++EEK G
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEE--------------EEKEEEKEEDEEEEEKEG 163


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,287,629
Number of Sequences: 37866
Number of extensions: 829603
Number of successful extensions: 4636
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 81
Number of HSP's that attempted gapping in prelim test: 4225
Number of HSP's gapped (non-prelim): 326
length of query: 471
length of database: 18,247,518
effective HSP length: 106
effective length of query: 365
effective length of database: 14,233,722
effective search space: 5195308530
effective search space used: 5195308530
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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