Guide to the Human Genome
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Search of human proteins with 223972690

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223972690 adenosine deaminase domain containing 2 isoform 2
[Homo sapiens]
         (583 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223972690 adenosine deaminase domain containing 2 isoform 2 [...  1191   0.0  
gi|223972688 adenosine deaminase domain containing 2 isoform 1 [...   901   0.0  
gi|226530771 adenosine deaminase domain containing 1 (testis-spe...   189   8e-48
gi|21245124 adenosine deaminase domain containing 1 (testis-spec...   189   8e-48
gi|226529650 adenosine deaminase domain containing 1 (testis-spe...   169   6e-42
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s...   142   6e-34
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]       135   1e-31
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo...   132   1e-30
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa...   119   8e-27
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa...   119   8e-27
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa...   115   1e-25
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa...   115   1e-25
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s...    84   5e-16
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s...    79   1e-14
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]         43   7e-04
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             42   0.002
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    41   0.003
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              40   0.006
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          40   0.008
gi|122937321 UNC homeobox [Homo sapiens]                               39   0.010
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]               39   0.013
gi|239735519 SET binding factor 1 [Homo sapiens]                       38   0.023
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...    38   0.023
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...    38   0.023
gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]            38   0.023
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    38   0.023
gi|45433499 zinc finger, DHHC-type containing 18 [Homo sapiens]        36   0.11 
gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens]    35   0.15 
gi|112421108 capicua homolog [Homo sapiens]                            35   0.15 
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                35   0.19 

>gi|223972690 adenosine deaminase domain containing 2 isoform 2
           [Homo sapiens]
          Length = 583

 Score = 1191 bits (3080), Expect = 0.0
 Identities = 583/583 (100%), Positives = 583/583 (100%)

Query: 1   MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60
           MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ
Sbjct: 1   MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60

Query: 61  VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120
           VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL
Sbjct: 61  VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120

Query: 121 TEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIR 180
           TEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIR
Sbjct: 121 TEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIR 180

Query: 181 SQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGV 240
           SQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGV
Sbjct: 181 SQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGV 240

Query: 241 ILEREIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQ 300
           ILEREIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQ
Sbjct: 241 ILEREIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQ 300

Query: 301 LLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGL 360
           LLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGL
Sbjct: 301 LLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGL 360

Query: 361 PHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPL 420
           PHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPL
Sbjct: 361 PHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPL 420

Query: 421 YSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPD 480
           YSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPD
Sbjct: 421 YSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPD 480

Query: 481 TCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLL 540
           TCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLL
Sbjct: 481 TCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLL 540

Query: 541 ALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN 583
           ALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN
Sbjct: 541 ALKTYEAAKAGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN 583


>gi|223972688 adenosine deaminase domain containing 2 isoform 1
           [Homo sapiens]
          Length = 665

 Score =  901 bits (2329), Expect = 0.0
 Identities = 444/454 (97%), Positives = 444/454 (97%), Gaps = 10/454 (2%)

Query: 140 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAP 199
           GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAP
Sbjct: 212 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAP 271

Query: 200 LSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILER----------EIPRA 249
           LSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILER          EIPRA
Sbjct: 272 LSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILERGWAVSAPSCTEIPRA 331

Query: 250 RGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGP 309
           RGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGP
Sbjct: 332 RGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGP 391

Query: 310 KGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQ 369
           KGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQ
Sbjct: 392 KGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQ 451

Query: 370 AHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILAD 429
           AHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILAD
Sbjct: 452 AHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILAD 511

Query: 430 SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNW 489
           SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNW
Sbjct: 512 SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNW 571

Query: 490 SLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK 549
           SLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK
Sbjct: 572 SLGDPGIEVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK 631

Query: 550 AGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN 583
           AGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN
Sbjct: 632 AGPYQEARRQLSLLLDQQGLGAWPSKPLVGKFRN 665



 Score =  290 bits (742), Expect = 3e-78
 Identities = 141/145 (97%), Positives = 142/145 (97%)

Query: 1   MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60
           MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ
Sbjct: 1   MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60

Query: 61  VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120
           VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL
Sbjct: 61  VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLL 120

Query: 121 TEYAASLGIFLLFREDQPPGPCFPF 145
           TEYAASLGIFLLFREDQPPG  F +
Sbjct: 121 TEYAASLGIFLLFREDQPPGKVFKY 145


>gi|226530771 adenosine deaminase domain containing 1
           (testis-specific) isoform 3 [Homo sapiens]
          Length = 558

 Score =  189 bits (479), Expect = 8e-48
 Identities = 155/468 (33%), Positives = 236/468 (50%), Gaps = 44/468 (9%)

Query: 140 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESP--QTSSRPP- 196
           GP F F   A +DG+    G   +K E++  AA  AL  +  QL+ PE    +TS  PP 
Sbjct: 107 GPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPEPRILETSGPPPF 163

Query: 197 ------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWACKGTVAGVILER 244
                 L+ L+  + + +E R       + +V   F+ L+  RS Y     ++A  I+ER
Sbjct: 164 PAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIER 223

Query: 245 EIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLA 304
               A  H     ++VA+GTG    +  ++  G+ LHD H +V ARR+LLR+ +RQLLL 
Sbjct: 224 ----AGQH-----EVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLF 274

Query: 305 TQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAAR---DIYLPPTSEGGLP 361
               P   E+S+   +P      TLK  + + LY++  PKG+A+    + L P S     
Sbjct: 275 YSKNPAMMEKSIFCTEP-TSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE 333

Query: 362 HSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLY 421
            +  + L   V G++    Y  P      +  +S+SDKL RW VLG+ GALL+H + P+Y
Sbjct: 334 ANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVY 392

Query: 422 STSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPD 480
            +S+++ D +C D   L  AI  R  +D  L   LP  Y+    H+   P   P +   +
Sbjct: 393 ISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 450

Query: 481 TCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGPPSRLCKASFLRAFHQAARAVGK 536
             + LSLNW+ GD  +E+VD  +G++  +    + +   SRLCKA+ L  F+  A+   K
Sbjct: 451 -YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKE-AK 508

Query: 537 PYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAWPSK-PLVGKF 581
             LL   TY AAK  +  YQEA+ +L   L Q G G+W  K P + +F
Sbjct: 509 KELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 556


>gi|21245124 adenosine deaminase domain containing 1
           (testis-specific) isoform 1 [Homo sapiens]
          Length = 576

 Score =  189 bits (479), Expect = 8e-48
 Identities = 155/468 (33%), Positives = 236/468 (50%), Gaps = 44/468 (9%)

Query: 140 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESP--QTSSRPP- 196
           GP F F   A +DG+    G   +K E++  AA  AL  +  QL+ PE    +TS  PP 
Sbjct: 125 GPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPEPRILETSGPPPF 181

Query: 197 ------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWACKGTVAGVILER 244
                 L+ L+  + + +E R       + +V   F+ L+  RS Y     ++A  I+ER
Sbjct: 182 PAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIER 241

Query: 245 EIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLA 304
               A  H     ++VA+GTG    +  ++  G+ LHD H +V ARR+LLR+ +RQLLL 
Sbjct: 242 ----AGQH-----EVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLF 292

Query: 305 TQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAAR---DIYLPPTSEGGLP 361
               P   E+S+   +P      TLK  + + LY++  PKG+A+    + L P S     
Sbjct: 293 YSKNPAMMEKSIFCTEP-TSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE 351

Query: 362 HSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLY 421
            +  + L   V G++    Y  P      +  +S+SDKL RW VLG+ GALL+H + P+Y
Sbjct: 352 ANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVY 410

Query: 422 STSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPD 480
            +S+++ D +C D   L  AI  R  +D  L   LP  Y+    H+   P   P +   +
Sbjct: 411 ISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 468

Query: 481 TCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGPPSRLCKASFLRAFHQAARAVGK 536
             + LSLNW+ GD  +E+VD  +G++  +    + +   SRLCKA+ L  F+  A+   K
Sbjct: 469 -YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKE-AK 526

Query: 537 PYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAWPSK-PLVGKF 581
             LL   TY AAK  +  YQEA+ +L   L Q G G+W  K P + +F
Sbjct: 527 KELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 574


>gi|226529650 adenosine deaminase domain containing 1
           (testis-specific) isoform 2 [Homo sapiens]
          Length = 565

 Score =  169 bits (428), Expect = 6e-42
 Identities = 149/468 (31%), Positives = 228/468 (48%), Gaps = 55/468 (11%)

Query: 140 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESP--QTSSRPP- 196
           GP F F   A +DG+    G   +K E++  AA  AL  +  QL+ PE    +TS  PP 
Sbjct: 125 GPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPEPRILETSGPPPF 181

Query: 197 ------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWACKGTVAGVILER 244
                 L+ L+  + + +E R       + +V   F+ L+  RS Y     ++A  I+ER
Sbjct: 182 PAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIER 241

Query: 245 EIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLA 304
               A  H     ++VA+GTG    +  ++  G+ LHD H +V ARR+LL          
Sbjct: 242 ----AGQH-----EVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLL---------- 282

Query: 305 TQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAAR---DIYLPPTSEGGLP 361
               P   E+S+   +P      TLK  + + LY++  PKG+A+    + L P S     
Sbjct: 283 -SKNPAMMEKSIFCTEPTSNL-LTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE 340

Query: 362 HSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLY 421
            +  + L   V G++    Y  P      +  +S+SDKL RW VLG+ GALL+H + P+Y
Sbjct: 341 ANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVY 399

Query: 422 STSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPD 480
            +S+++ D +C D   L  AI  R  +D  L   LP  Y+    H+   P   P +   +
Sbjct: 400 ISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 457

Query: 481 TCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGPPSRLCKASFLRAFHQAARAVGK 536
             + LSLNW+ GD  +E+VD  +G++  +    + +   SRLCKA+ L  F+  A+   K
Sbjct: 458 -YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKE-AK 515

Query: 537 PYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAWPSK-PLVGKF 581
             LL   TY AAK  +  YQEA+ +L   L Q G G+W  K P + +F
Sbjct: 516 KELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 563


>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
           sapiens]
          Length = 701

 Score =  142 bits (359), Expect = 6e-34
 Identities = 148/500 (29%), Positives = 220/500 (44%), Gaps = 51/500 (10%)

Query: 100 PPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAG 159
           PP  +  P   P     V +L E    L    L    +     F  SV   +DG     G
Sbjct: 220 PPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVV--VDGQFFE-G 276

Query: 160 TANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTH--EQRCAALVS 217
           +  +K  AK +AA SAL  I     N    QT SR P+    ++  L        + LV 
Sbjct: 277 SGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVL 332

Query: 218 AGFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFS 276
             F  L D  S   A +  +AGV++        G   +  K++++ TG+ C  G ++   
Sbjct: 333 GKFGDLTDNFSSPHARRKVLAGVVM------TTGTDVKDAKVISVSTGTKCINGEYMSDR 386

Query: 277 GQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLH 336
           G  L+DCH  +I+RR+LLRFL+ QL L        K       + G    F LK  V  H
Sbjct: 387 GLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG---FRLKENVQFH 443

Query: 337 LYISNTPKGAARDIYLP--PTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGC- 393
           LYIS +P G AR I+ P  P  E      P  + +  +  +++      P   +  +   
Sbjct: 444 LYISTSPCGDAR-IFSPHEPILEEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTW 502

Query: 394 -----------LSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIH 442
                      +S SDK+ARW V+G+ G+LL+  V P+Y +S+IL    H    LSRA++
Sbjct: 503 DGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHG-DHLSRAMY 561

Query: 443 TRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVA 502
            R  + ++    LPP Y      L +G   A +   P      S+NW++GD  IEV++  
Sbjct: 562 QR--ISNI--EDLPPLYTLNK-PLLSGISNAEAR-QPGKAPNFSVNWTVGDSAIEVINAT 615

Query: 503 TGRVKANAALGPPSRLCK----ASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEA 556
           TG+ +    LG  SRLCK      ++R   +    + +  +     Y  +K  A  YQ A
Sbjct: 616 TGKDE----LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAA 671

Query: 557 RRQLSLLLDQQGLGAWPSKP 576
           + +L     + GLGAW  KP
Sbjct: 672 KARLFTAFIKAGLGAWVEKP 691


>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
          Length = 739

 Score =  135 bits (339), Expect = 1e-31
 Identities = 140/487 (28%), Positives = 214/487 (43%), Gaps = 52/487 (10%)

Query: 111 PPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQ 170
           P     V LL    A L    L    +     F  +VS  +DG     G+  SK  A+ Q
Sbjct: 274 PGERNPVVLLNRLRAGLRYVCLAEPAERRARSFVMAVS--VDGRTFE-GSGRSKKLARGQ 330

Query: 171 AALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPY 230
           AA +AL  +        +P  + R P+     ++I       + LV+  F  +  + +P 
Sbjct: 331 AAQAALQELFDIQMPGHAPGRARRTPMPQEFADSI-------SQLVTQKFREVTTDLTPM 383

Query: 231 WACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIA 289
            A    +AG+++ + +   +  V      VAL +G+ C +G  L   G  ++DCH  V+A
Sbjct: 384 HARHKALAGIVMTKGLDARQAQV------VALSSGTKCISGEHLSDQGLVVNDCHAEVVA 437

Query: 290 RRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARD 349
           RRA L FL+ QL L      +  E+S+       G  + L+  +  HLY+S +P G AR 
Sbjct: 438 RRAFLHFLYTQLELHLSKRREDSERSIFVRLKEGG--YRLRENILFHLYVSTSPCGDAR- 494

Query: 350 IYLPPTSEGGLPHSPPM--RLQAHVLGQLKP----VCYVAPSLCDTHVGCL--------S 395
           ++ P      L  S  +  + + H+  +++     V    PS   T  G L        S
Sbjct: 495 LHSPYEITTDLHSSKHLVRKFRGHLRTKIESGEGTVPVRGPSAVQTWDGVLLGEQLITMS 554

Query: 396 ASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCL 455
            +DK+ARW VLGL GALL+H V P+Y  S+++  S H    L+R +  R     + G   
Sbjct: 555 CTDKIARWNVLGLQGALLSHFVEPVYLQSIVVG-SLHHTGHLARVMSHR-----MEGVGQ 608

Query: 456 PPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALGPP 515
            P   R    L +G   A +   P      S+NW +G   +E+++  TGR     + G P
Sbjct: 609 LPASYRHNRPLLSGVSDAEAR-QPGKSPPFSMNWVVGSADLEIINATTGR----RSCGGP 663

Query: 516 SRLCK----ASFLRAFHQAARAVGKPYLLALKTYEAAKAG--PYQEARRQLSLLLDQQGL 569
           SRLCK    A + R + + +     P       Y  AK G   YQ  ++QL     + GL
Sbjct: 664 SRLCKHVLSARWARLYGRLSTRTPSPGDTP-SMYCEAKLGAHTYQSVKQQLFKAFQKAGL 722

Query: 570 GAWPSKP 576
           G W  KP
Sbjct: 723 GTWVRKP 729


>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
           sapiens]
          Length = 674

 Score =  132 bits (331), Expect = 1e-30
 Identities = 145/481 (30%), Positives = 211/481 (43%), Gaps = 59/481 (12%)

Query: 100 PPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAG 159
           PP  +  P   P     V +L E    L    L    +     F  SV   +DG     G
Sbjct: 220 PPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVV--VDGQFFE-G 276

Query: 160 TANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTH--EQRCAALVS 217
           +  +K  AK +AA SAL  I     N    QT SR P+    ++  L        + LV 
Sbjct: 277 SGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVL 332

Query: 218 AGFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFS 276
             F  L D  S   A +  +AGV++        G   +  K++++ TG+ C  G ++   
Sbjct: 333 GKFGDLTDNFSSPHARRKVLAGVVM------TTGTDVKDAKVISVSTGTKCINGEYMSDR 386

Query: 277 GQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLH 336
           G  L+DCH  +I+RR+LLRFL+ QL L        K       + G    F LK  V  H
Sbjct: 387 GLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGG---FRLKENVQFH 443

Query: 337 LYISNTPKGAARDIYLP--PTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGC- 393
           LYIS +P G AR I+ P  P  E      P  + +  +  +++      P   +  +   
Sbjct: 444 LYISTSPCGDAR-IFSPHEPILEEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTW 502

Query: 394 -----------LSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIH 442
                      +S SDK+ARW V+G+ G+LL+  V P+Y +S+IL    H    LSRA++
Sbjct: 503 DGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHG-DHLSRAMY 561

Query: 443 TRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVA 502
            R  + ++    LPP Y      L +G   A +   P      S+NW++GD  IEV++  
Sbjct: 562 QR--ISNI--EDLPPLYTLNK-PLLSGISNAEAR-QPGKAPNFSVNWTVGDSAIEVINAT 615

Query: 503 TGRVKANAALGPPSRLCK-ASFLR--------AFHQAARAVGKPYL-----LALKTYEAA 548
           TG+ +    LG  SRLCK A + R          H     + KP +     LA K Y+AA
Sbjct: 616 TGKDE----LGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAA 671

Query: 549 K 549
           K
Sbjct: 672 K 672


>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
            sapiens]
          Length = 1181

 Score =  119 bits (298), Expect = 8e-27
 Identities = 136/482 (28%), Positives = 206/482 (42%), Gaps = 48/482 (9%)

Query: 120  LTEYAASLGIFLLFR-EDQPPGPCFP-FSVSAELDGVVCPAGTANSKTEAKQQAALSALC 177
            L EYA S G    F+  DQ   P  P F   A++ G   PA  A+SK + KQ+AA +AL 
Sbjct: 712  LLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALR 771

Query: 178  YIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTV 237
             +  + E  E    +  P       + I     RC       F+ L +   P    +  +
Sbjct: 772  VLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRC-------FNTLTNSFQPSLLGRKIL 824

Query: 238  AGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRF 296
            A +I++++        +++  +V+LGTG+ C  G  L   G+ ++DCH  +I+RR  +RF
Sbjct: 825  AAIIMKKDS-------EDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRF 877

Query: 297  LFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKG-------AARD 349
            L+ +L+   +   +  + S+  P  G G    +K  V  HLYIS  P G       +  D
Sbjct: 878  LYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 933

Query: 350  IYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG--------CLSASD 398
              +  T     P   +P   +L+  V      +   +  +  T  G         +S SD
Sbjct: 934  RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 993

Query: 399  KLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLD-SVLGPCLPP 457
            K+ RW VLGL GALL H + P+Y  S+ L         L+RAI  R   D S     L  
Sbjct: 994  KILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRVTRDGSAFEDGLRH 1052

Query: 458  PYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVATGRVKANAALGPP 515
            P++    H   G   +  S+      +  S+NW L D   +E++D   G V  +      
Sbjct: 1053 PFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV--DGPRNEL 1108

Query: 516  SRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLSLLLDQQGLGAWPS 574
            SR+ K +    F +      +  LL L   EA KA   Y+ A+      L   G G W S
Sbjct: 1109 SRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWIS 1168

Query: 575  KP 576
            KP
Sbjct: 1169 KP 1170


>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
            sapiens]
          Length = 1200

 Score =  119 bits (298), Expect = 8e-27
 Identities = 136/482 (28%), Positives = 206/482 (42%), Gaps = 48/482 (9%)

Query: 120  LTEYAASLGIFLLFR-EDQPPGPCFP-FSVSAELDGVVCPAGTANSKTEAKQQAALSALC 177
            L EYA S G    F+  DQ   P  P F   A++ G   PA  A+SK + KQ+AA +AL 
Sbjct: 731  LLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALR 790

Query: 178  YIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTV 237
             +  + E  E    +  P       + I     RC       F+ L +   P    +  +
Sbjct: 791  VLIGENEKAERMGFTELPLTGSTFHDQIAMLSHRC-------FNTLTNSFQPSLLGRKIL 843

Query: 238  AGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSGQQLHDCHGLVIARRALLRF 296
            A +I++++        +++  +V+LGTG+ C  G  L   G+ ++DCH  +I+RR  +RF
Sbjct: 844  AAIIMKKDS-------EDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRF 896

Query: 297  LFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKG-------AARD 349
            L+ +L+   +   +  + S+  P  G G    +K  V  HLYIS  P G       +  D
Sbjct: 897  LYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 952

Query: 350  IYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLCDTHVG--------CLSASD 398
              +  T     P   +P   +L+  V      +   +  +  T  G         +S SD
Sbjct: 953  RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 1012

Query: 399  KLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLD-SVLGPCLPP 457
            K+ RW VLGL GALL H + P+Y  S+ L         L+RAI  R   D S     L  
Sbjct: 1013 KILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTRAICCRVTRDGSAFEDGLRH 1071

Query: 458  PYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GIEVVDVATGRVKANAALGPP 515
            P++    H   G   +  S+      +  S+NW L D   +E++D   G V  +      
Sbjct: 1072 PFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV--DGPRNEL 1127

Query: 516  SRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQEARRQLSLLLDQQGLGAWPS 574
            SR+ K +    F +      +  LL L   EA KA   Y+ A+      L   G G W S
Sbjct: 1128 SRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWIS 1187

Query: 575  KP 576
            KP
Sbjct: 1188 KP 1189


>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
           sapiens]
          Length = 931

 Score =  115 bits (288), Expect = 1e-25
 Identities = 137/501 (27%), Positives = 210/501 (41%), Gaps = 60/501 (11%)

Query: 120 LTEYAASLGIFLLFR-EDQPPGPCFP-FSVSAELDGVVCPAGTANSKTEAKQQAALSALC 177
           L EYA S G    F+  DQ   P  P F   A++ G   PA  A+SK + KQ+AA +AL 
Sbjct: 436 LLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALR 495

Query: 178 YIRSQLENPESPQTSSRPPLAPLSVENIL-------------------THEQRCAALVSA 218
            +  + E  E    +   P+   S+   +                   T   + A L   
Sbjct: 496 VLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHR 555

Query: 219 GFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSG 277
            F+ L +   P    +  +A +I++++        +++  +V+LGTG+ C  G  L   G
Sbjct: 556 CFNTLTNSFQPSLLGRKILAAIIMKKDS-------EDMGVVVSLGTGNRCVKGDSLSLKG 608

Query: 278 QQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHL 337
           + ++DCH  +I+RR  +RFL+ +L+   +   +  + S+  P  G G    +K  V  HL
Sbjct: 609 ETVNDCHAEIISRRGFIRFLYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHL 664

Query: 338 YISNTPKG-------AARDIYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLC 387
           YIS  P G       +  D  +  T     P   +P   +L+  V      +   +  + 
Sbjct: 665 YISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIV 724

Query: 388 DTHVG--------CLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSR 439
            T  G         +S SDK+ RW VLGL GALL H + P+Y  S+ L         L+R
Sbjct: 725 PTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTR 783

Query: 440 AIHTRPCLD-SVLGPCLPPPYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GI 496
           AI  R   D S     L  P++    H   G   +  S+      +  S+NW L D   +
Sbjct: 784 AICCRVTRDGSAFEDGLRHPFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDL 841

Query: 497 EVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQE 555
           E++D   G V  +      SR+ K +    F +      +  LL L   EA KA   Y+ 
Sbjct: 842 EILDGTRGTV--DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYET 899

Query: 556 ARRQLSLLLDQQGLGAWPSKP 576
           A+      L   G G W SKP
Sbjct: 900 AKNYFKKGLKDMGYGNWISKP 920


>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
            sapiens]
          Length = 1226

 Score =  115 bits (288), Expect = 1e-25
 Identities = 137/501 (27%), Positives = 210/501 (41%), Gaps = 60/501 (11%)

Query: 120  LTEYAASLGIFLLFR-EDQPPGPCFP-FSVSAELDGVVCPAGTANSKTEAKQQAALSALC 177
            L EYA S G    F+  DQ   P  P F   A++ G   PA  A+SK + KQ+AA +AL 
Sbjct: 731  LLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALR 790

Query: 178  YIRSQLENPESPQTSSRPPLAPLSVENIL-------------------THEQRCAALVSA 218
             +  + E  E    +   P+   S+   +                   T   + A L   
Sbjct: 791  VLIGENEKAERMGFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTFHDQIAMLSHR 850

Query: 219  GFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFSG 277
             F+ L +   P    +  +A +I++++        +++  +V+LGTG+ C  G  L   G
Sbjct: 851  CFNTLTNSFQPSLLGRKILAAIIMKKDS-------EDMGVVVSLGTGNRCVKGDSLSLKG 903

Query: 278  QQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHL 337
            + ++DCH  +I+RR  +RFL+ +L+   +   +  + S+  P  G G    +K  V  HL
Sbjct: 904  ETVNDCHAEIISRRGFIRFLYSELM---KYNSQTAKDSIFEPAKG-GEKLQIKKTVSFHL 959

Query: 338  YISNTPKG-------AARDIYLPPTSEGGLP--HSPPM-RLQAHVLGQLKPVCYVAPSLC 387
            YIS  P G       +  D  +  T     P   +P   +L+  V      +   +  + 
Sbjct: 960  YISTAPCGDGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIV 1019

Query: 388  DTHVG--------CLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSR 439
             T  G         +S SDK+ RW VLGL GALL H + P+Y  S+ L         L+R
Sbjct: 1020 PTWDGIRLGERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLG-YLFSQGHLTR 1078

Query: 440  AIHTRPCLD-SVLGPCLPPPYVRTALHLFAG-PPVAPSEPTPDTCRGLSLNWSLGDP-GI 496
            AI  R   D S     L  P++    H   G   +  S+      +  S+NW L D   +
Sbjct: 1079 AICCRVTRDGSAFEDGLRHPFI--VNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDL 1136

Query: 497  EVVDVATGRVKANAALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAG-PYQE 555
            E++D   G V  +      SR+ K +    F +      +  LL L   EA KA   Y+ 
Sbjct: 1137 EILDGTRGTV--DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYET 1194

Query: 556  ARRQLSLLLDQQGLGAWPSKP 576
            A+      L   G G W SKP
Sbjct: 1195 AKNYFKKGLKDMGYGNWISKP 1215


>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
           sapiens]
          Length = 741

 Score = 83.6 bits (205), Expect = 5e-16
 Identities = 64/189 (33%), Positives = 97/189 (51%), Gaps = 17/189 (8%)

Query: 394 LSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGP 453
           +S SDK+ARW V+G+ G+LL+  V P+Y +S+IL    H    LSRA++ R  + ++   
Sbjct: 554 MSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--E 608

Query: 454 CLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALG 513
            LPP Y      L +G   A +   P      S+NW++GD  IEV++  TG+ +    LG
Sbjct: 609 DLPPLYTLNK-PLLSGISNAEAR-QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LG 662

Query: 514 PPSRLCK----ASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQ 567
             SRLCK      ++R   +    + +  +     Y  +K  A  YQ A+ +L     + 
Sbjct: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKA 722

Query: 568 GLGAWPSKP 576
           GLGAW  KP
Sbjct: 723 GLGAWVEKP 731



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 83/264 (31%), Positives = 114/264 (43%), Gaps = 22/264 (8%)

Query: 100 PPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAG 159
           PP  +  P   P     V +L E    L    L    +     F  SV   +DG     G
Sbjct: 220 PPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVV--VDGQFFE-G 276

Query: 160 TANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTH--EQRCAALVS 217
           +  +K  AK +AA SAL  I     N    QT SR P+    ++  L        + LV 
Sbjct: 277 SGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVL 332

Query: 218 AGFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFS 276
             F  L D  S   A +  +AGV++        G   +  K++++ TG+ C  G ++   
Sbjct: 333 GKFGDLTDNFSSPHARRKVLAGVVM------TTGTDVKDAKVISVSTGTKCINGEYMSDR 386

Query: 277 GQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLH 336
           G  L+DCH  +I+RR+LLRFL+ QL L        K       + G    F LK  V  H
Sbjct: 387 GLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERG---GFRLKENVQFH 443

Query: 337 LYISNTPKGAARDIYLP--PTSEG 358
           LYIS +P G AR I+ P  P  EG
Sbjct: 444 LYISTSPCGDAR-IFSPHEPILEG 466


>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
           sapiens]
          Length = 714

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 83/264 (31%), Positives = 114/264 (43%), Gaps = 22/264 (8%)

Query: 100 PPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAG 159
           PP  +  P   P     V +L E    L    L    +     F  SV   +DG     G
Sbjct: 220 PPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVV--VDGQFFE-G 276

Query: 160 TANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTH--EQRCAALVS 217
           +  +K  AK +AA SAL  I     N    QT SR P+    ++  L        + LV 
Sbjct: 277 SGRNKKLAKARAAQSALAAIF----NLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVL 332

Query: 218 AGFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAG-WLEFS 276
             F  L D  S   A +  +AGV++        G   +  K++++ TG+ C  G ++   
Sbjct: 333 GKFGDLTDNFSSPHARRKVLAGVVM------TTGTDVKDAKVISVSTGTKCINGEYMSDR 386

Query: 277 GQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLH 336
           G  L+DCH  +I+RR+LLRFL+ QL L        K       + G    F LK  V  H
Sbjct: 387 GLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERG---GFRLKENVQFH 443

Query: 337 LYISNTPKGAARDIYLP--PTSEG 358
           LYIS +P G AR I+ P  P  EG
Sbjct: 444 LYISTSPCGDAR-IFSPHEPILEG 466



 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 61/170 (35%), Positives = 88/170 (51%), Gaps = 25/170 (14%)

Query: 394 LSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGP 453
           +S SDK+ARW V+G+ G+LL+  V P+Y +S+IL    H    LSRA++ R  + ++   
Sbjct: 554 MSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHG-DHLSRAMYQR--ISNI--E 608

Query: 454 CLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKANAALG 513
            LPP Y      L +G   A +   P      S+NW++GD  IEV++  TG+ +    LG
Sbjct: 609 DLPPLYTLNK-PLLSGISNAEAR-QPGKAPNFSVNWTVGDSAIEVINATTGKDE----LG 662

Query: 514 PPSRLCK-ASFLR--------AFHQAARAVGKPYL-----LALKTYEAAK 549
             SRLCK A + R          H     + KP +     LA K Y+AAK
Sbjct: 663 RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712


>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
          Length = 502

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 31/91 (34%), Positives = 47/91 (51%), Gaps = 6/91 (6%)

Query: 258 KLVALGTGSSCCA-GWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSV 316
           ++V++GTG+ C     +  +G  L+D H  VIARR+  R+L  QL LA       KE S+
Sbjct: 60  EIVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQLAA----TLKEDSI 115

Query: 317 LAPQPGPGPPFTLKPRVFLHLYISNTPKGAA 347
             P    G  + L+  +    + S+TP G A
Sbjct: 116 FVPGTQKG-VWKLRRDLIFVFFSSHTPCGDA 145



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 20/49 (40%), Positives = 32/49 (65%), Gaps = 1/49 (2%)

Query: 394 LSASDKLARWAVLGLGGALLAHLV-SPLYSTSLILADSCHDPPTLSRAI 441
           +S SDK+ARW VLG  GALL HL+  P+Y +++++    +    + RA+
Sbjct: 297 MSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRAL 345


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 19/121 (15%)

Query: 2   ASASQGADDDGSRR----------KPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPAT 51
           +SA  GA+ DG +           KPR+   LQ    P   RP PA  +++    PAP T
Sbjct: 259 SSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPT 318

Query: 52  YRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDP 111
            R      Q +++        AG   L   R  E     + K    P P  G   P KDP
Sbjct: 319 PRPRSSLQQENLVEQ------AGSSSLVNGRLHE---LPVPKPRGTPKPSEGTPAPRKDP 369

Query: 112 P 112
           P
Sbjct: 370 P 370


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
            sapiens]
          Length = 1336

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 54/189 (28%), Positives = 75/189 (39%), Gaps = 41/189 (21%)

Query: 29   PRPWRPLPAQAQSAWGPAPAPATY--RAEGGWPQVSVLRDSGPGAGAGVGELGAARAW-- 84
            P P +PLP+ A  A  PAP PA +  R      +    + +GP  GAG+ + G  R +  
Sbjct: 909  PPPPQPLPSPAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLAD-GFHRYYGP 967

Query: 85   ---ENLGEQMGKAPRVPVPPAG--LSLPLKDPPASQAVSLLTEYAASLGIFLLFRED--- 136
               + LG  +G+A   P   AG  LS P   PP     S           F + R+    
Sbjct: 968  IEPQGLGLGLGEARAAPRGAAGRPLSPPAAQPPQKPPPS----------YFAIVRDKEPA 1017

Query: 137  QPPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESP------Q 190
            +PP   FP   S        PA  A + T     A    LC +  + E+P +P       
Sbjct: 1018 EPPAGAFPGFPSP-------PAPPAAAAT-----AVGPPLCRLAFEDESPPAPARWPRSD 1065

Query: 191  TSSRPPLAP 199
              S+P L P
Sbjct: 1066 PESQPLLGP 1074


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 68/223 (30%), Positives = 82/223 (36%), Gaps = 72/223 (32%)

Query: 20   AASLQI----SPQPRPWRPLPAQAQSAWG-----PAPAPATYRAEGGWPQVSV------- 63
            A +LQI    SP P P  P PA A SA G     P   P      GG P+  V       
Sbjct: 822  ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTP 881

Query: 64   -------LRDSGPGAGAGVGELGAARAWENLGEQM-GKAPRVPVPPAGLSLPLKDPPASQ 115
                   LR  G   GA    LG +   + L   + G+A  VP P +GL   ++     +
Sbjct: 882  SLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVR----LK 937

Query: 116  AVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAGTAN---SKTEAKQQAA 172
            A SL    AAS G+       QP GP       AE      PA TA+   SK   K    
Sbjct: 938  ACSL----AASEGL----SSAQPNGP-----PEAEPRPPQSPASTASFIFSKGSRK---- 980

Query: 173  LSALCYIRSQLENPESPQTSS----------------RPPLAP 199
                     QLE P SP+T +                RPP AP
Sbjct: 981  --------LQLERPVSPETQADLQRNLVAELRSISEQRPPQAP 1015


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 30/107 (28%), Positives = 42/107 (39%), Gaps = 14/107 (13%)

Query: 48  APATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLP 107
           A AT  A GG    +    +  G GAG G  G     +   + +  +   P PPAG   P
Sbjct: 236 AAATAAAAGGGGSTA---STSGGVGAGAGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPP 292

Query: 108 LKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGV 154
           L  PP     + +T  +A           QPPGP  P ++     G+
Sbjct: 293 LTLPPTPSPATAVTAASA-----------QPPGPAPPITLEPPAPGL 328


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 39.3 bits (90), Expect = 0.010
 Identities = 39/126 (30%), Positives = 47/126 (37%), Gaps = 12/126 (9%)

Query: 27  PQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQV------SVLRDSGPGAGAGVGELGA 80
           PQPRP RP    A S    A   A  R   G P+       S+L DS P   A      A
Sbjct: 295 PQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAA 354

Query: 81  ARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLGIFLL--FREDQP 138
           A A  +    +  APR  +      L     P +Q +  L   AA  G   L    +D P
Sbjct: 355 AAAGLDFAPGLPCAPRTLIGKGHFLL----YPITQPLGFLVPQAALKGGAGLEPAPKDAP 410

Query: 139 PGPCFP 144
           P P  P
Sbjct: 411 PAPAVP 416


>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
          Length = 841

 Score = 38.9 bits (89), Expect = 0.013
 Identities = 59/251 (23%), Positives = 83/251 (33%), Gaps = 47/251 (18%)

Query: 2   ASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQV 61
           A ++     DG  R P L  S + +    P   +PA+ +    P P P         P  
Sbjct: 343 AKSASRTPGDGVSRLPVLCHSKEPAGST-PAPQVPARERETPPPPPPPPAANLLLLGPSG 401

Query: 62  SVLRDSGP----GAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAV 117
                S P    G+G   GE     +   +  +   AP  P  PA L   L  PP  +AV
Sbjct: 402 RARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAAL---LPGPPKDKAV 458

Query: 118 SLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALC 177
           S    Y+A   + +      P GP               P G    KTE +       LC
Sbjct: 459 SYTMVYSA---VKVTTHSVLPAGP---------------PLGAGEPKTEKEISVLHGMLC 500

Query: 178 YIRSQLENPESPQTSSRPPL--------APLSVENILTHEQRCAALVSAGFDLLLDERSP 229
                        TSSRPP+          +     + H + C A   +  D  +   +P
Sbjct: 501 -------------TSSRPPVPGKTSPHGGAMGAAAGVLHHRGCLASPHSLPDPTVGPLTP 547

Query: 230 YWACKGTVAGV 240
            W    T AG+
Sbjct: 548 LWTYPATAAGL 558


>gi|239735519 SET binding factor 1 [Homo sapiens]
          Length = 1893

 Score = 38.1 bits (87), Expect = 0.023
 Identities = 45/175 (25%), Positives = 70/175 (40%), Gaps = 34/175 (19%)

Query: 36   PAQAQSAWGPAPAPATYRAEGGWPQ-----VSVLRDSGPGAGAGV------------GEL 78
            P   + A GP   P   R++GG PQ     V    DS P A                 EL
Sbjct: 1631 PYDWELAQGPPEPPEEERSDGGAPQSRRRVVWPCYDSCPRAQPDAISRLLEELQRLETEL 1690

Query: 79   G-AARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQ 137
            G  A  W++  +++  A R+   P G     +  P+S  VS    +  SLG++L   ++ 
Sbjct: 1691 GQPAERWKDTWDRVKAAQRLEGRPDG-----RGTPSSLLVSTAPHHRRSLGVYL---QEG 1742

Query: 138  PPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTS 192
            P G     S+ ++         ++ S T   +QAA  +   + SQ +  ES   S
Sbjct: 1743 PVGSTLSLSLDSD--------QSSGSTTSGSRQAARRSTSTLYSQFQTAESENRS 1789


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score = 38.1 bits (87), Expect = 0.023
 Identities = 54/182 (29%), Positives = 72/182 (39%), Gaps = 34/182 (18%)

Query: 29  PRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLG 88
           PRP  P P        PAP+P T+ ++   P  SV R  GPG GA  G  G  R  E   
Sbjct: 125 PRPPPPRPGMHSPPPRPAPSPGTWESQ---PARSV-RLGGPGGGA--GGAGGGRVLECPS 178

Query: 89  EQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVS 148
            ++      P PPA     L+D P +       +Y    G F  +RE    G    FS S
Sbjct: 179 IRITSISPTPEPPAA----LEDNPDAWGDGSPRDYPPPEG-FGGYREAGGQGGGAFFSPS 233

Query: 149 AELDGVVCPAGTANSK----TEAKQQAALSALC-YIRSQLENP----------ESPQTSS 193
                   P  ++ S     ++A  +AAL A C  + S+L              SP+ S 
Sbjct: 234 --------PGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASP 285

Query: 194 RP 195
           RP
Sbjct: 286 RP 287


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score = 38.1 bits (87), Expect = 0.023
 Identities = 54/182 (29%), Positives = 72/182 (39%), Gaps = 34/182 (18%)

Query: 29  PRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLG 88
           PRP  P P        PAP+P T+ ++   P  SV R  GPG GA  G  G  R  E   
Sbjct: 62  PRPPPPRPGMHSPPPRPAPSPGTWESQ---PARSV-RLGGPGGGA--GGAGGGRVLECPS 115

Query: 89  EQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVS 148
            ++      P PPA     L+D P +       +Y    G F  +RE    G    FS S
Sbjct: 116 IRITSISPTPEPPAA----LEDNPDAWGDGSPRDYPPPEG-FGGYREAGGQGGGAFFSPS 170

Query: 149 AELDGVVCPAGTANSK----TEAKQQAALSALC-YIRSQLENP----------ESPQTSS 193
                   P  ++ S     ++A  +AAL A C  + S+L              SP+ S 
Sbjct: 171 --------PGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASP 222

Query: 194 RP 195
           RP
Sbjct: 223 RP 224


>gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 257

 Score = 38.1 bits (87), Expect = 0.023
 Identities = 33/101 (32%), Positives = 40/101 (39%), Gaps = 7/101 (6%)

Query: 12  GSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPA--TYRAEGGWPQVSVLRDSGP 69
           GS+  P     L    +   W P PA+A  A G    PA    RA G     +  R   P
Sbjct: 64  GSQEHPGAGGPLCFPARSAAWGP-PARASRAAGRRAGPAGPPCRAPGRGRAAATRRSPAP 122

Query: 70  GAG----AGVGELGAARAWENLGEQMGKAPRVPVPPAGLSL 106
           G      AGV   G A A  + G +   A R+P P  G SL
Sbjct: 123 GTARGSPAGVERAGGATAASSAGTRSVPARRLPPPCGGTSL 163


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 38.1 bits (87), Expect = 0.023
 Identities = 47/173 (27%), Positives = 60/173 (34%), Gaps = 31/173 (17%)

Query: 34  PLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMGK 93
           P+PA A  A GP PAPA      G   ++     GPG G G G               G 
Sbjct: 139 PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGP--------------GP 184

Query: 94  APRVPVPP-------AGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFS 146
            P  P  P          +L      A+ AVSL+    A+     L    +P  P     
Sbjct: 185 GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAA-----LLPLPKPAAPGTVIQ 239

Query: 147 VSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAP 199
               +     PA  A S   A   AA +A     +    P +P T +RPP  P
Sbjct: 240 TPPFVGAAAPPAPAAPSPPAAPAPAAPAA-----APPPPPPAPATLARPPGHP 287



 Score = 37.4 bits (85), Expect = 0.038
 Identities = 46/178 (25%), Positives = 63/178 (35%), Gaps = 20/178 (11%)

Query: 27  PQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWEN 86
           P   P  P PA AQ+      APA   A GG     V    GPGA A     G       
Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGG--PAGVSGQPGPGAAAAAPAPG------- 341

Query: 87  LGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFS 146
           +  +  K      PPA  +L     PAS A S++       G         PP P  P  
Sbjct: 342 VKAESPKRVVQAAPPAAQTLAASG-PASTAASMVIG-PTMQGALPSPAAVPPPAPGTPTG 399

Query: 147 VSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVEN 204
           +         P G A + T++  +   +    IR+ L          +PP  P +++N
Sbjct: 400 L---------PKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQN 448


>gi|45433499 zinc finger, DHHC-type containing 18 [Homo sapiens]
          Length = 388

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 11/68 (16%)

Query: 20 AASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELG 79
          AA L  SP  R  RP PA + +  GP PAP    A   W        SG G+G+G G LG
Sbjct: 13 AAPLPASPGAR--RPGPAASPTP-GPGPAPPAAPAPPRWSS------SGSGSGSGSGSLG 63

Query: 80 --AARAWE 85
              R WE
Sbjct: 64 RRPRRKWE 71


>gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens]
          Length = 773

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)

Query: 110 DPPASQAVSLLTEYAAS-LGIFLLFREDQPPGPCFPFSVSAELDGVVCPAGTANSKTEAK 168
           +P     V +L EY    L +  ++   +   P  PF  S  +DGV   +GTA+SK  AK
Sbjct: 506 NPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSEPFGASVTIDGVTYGSGTASSKKLAK 565

Query: 169 QQAALSAL 176
            +AA + L
Sbjct: 566 NKAARATL 573


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 30/88 (34%), Positives = 37/88 (42%), Gaps = 3/88 (3%)

Query: 35  LPAQAQSAWGPAPAPATYRA--EGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMG 92
           LP Q Q A  PAPAP T  A   G  P  S+     PG     G++ AA A       + 
Sbjct: 832 LPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTN-GKVLAATAPTPGIPILQ 890

Query: 93  KAPRVPVPPAGLSLPLKDPPASQAVSLL 120
             P  P P A    P++ PP   +  LL
Sbjct: 891 SVPSAPPPKAQSVSPVQAPPPGGSAQLL 918


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 46/185 (24%), Positives = 65/185 (35%), Gaps = 13/185 (7%)

Query: 1   MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQ 60
           + ++ QGA    S     L A  Q+ P  +  +P PAQ QS     P P      G   Q
Sbjct: 228 VVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQ 287

Query: 61  VSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAP-RVPVPPAGLSL--PLKDPPASQAV 117
            S      PGA  G   + AA       +  G  P    +PP  ++L  P    P     
Sbjct: 288 SSAPLPPFPGAATGPQPMMAA---AQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGP 344

Query: 118 SLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELD-------GVVCPAGTANSKTEAKQQ 170
           ++    A     F   +   PPG   P   S + +       G+  P+    S T A   
Sbjct: 345 AVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAAS 404

Query: 171 AALSA 175
            A +A
Sbjct: 405 PATAA 409


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,308,162
Number of Sequences: 37866
Number of extensions: 1653477
Number of successful extensions: 7097
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 147
Number of HSP's that attempted gapping in prelim test: 6782
Number of HSP's gapped (non-prelim): 422
length of query: 583
length of database: 18,247,518
effective HSP length: 108
effective length of query: 475
effective length of database: 14,157,990
effective search space: 6725045250
effective search space used: 6725045250
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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