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Search of human proteins with 223941798
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223941798 N-glycanase 1 isoform 2 [Homo sapiens]
(636 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223941798 N-glycanase 1 isoform 2 [Homo sapiens] 1280 0.0
gi|21314690 N-glycanase 1 isoform 1 [Homo sapiens] 1209 0.0
gi|223941803 N-glycanase 1 isoform 3 [Homo sapiens] 1130 0.0
gi|223941808 N-glycanase 1 isoform 4 [Homo sapiens] 977 0.0
gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein... 38 0.033
gi|13376854 UBX domain protein 6 [Homo sapiens] 37 0.042
gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens] 36 0.12
gi|46276885 WD repeat domain 78 isoform 2 [Homo sapiens] 36 0.12
gi|4502613 cyclin A [Homo sapiens] 35 0.28
gi|189011568 adenomatous polyposis coli [Homo sapiens] 34 0.36
gi|189011566 adenomatous polyposis coli [Homo sapiens] 34 0.36
gi|53759122 adenomatous polyposis coli [Homo sapiens] 34 0.36
gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens] 34 0.47
gi|50345997 E1A binding protein p300 [Homo sapiens] 33 0.61
gi|33946327 nucleoporin 214kDa [Homo sapiens] 33 1.0
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 33 1.0
gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens] 32 1.8
gi|183396804 Regulation of nuclear pre-mRNA domain containing 2 ... 32 1.8
gi|221139926 NHS-like 1 [Homo sapiens] 31 4.0
gi|23199971 T-cell activation Rho GTPase-activating protein isof... 31 4.0
gi|21314774 T-cell activation Rho GTPase-activating protein isof... 31 4.0
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 30 5.2
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 30 6.8
gi|16753207 ubiquilin 2 [Homo sapiens] 30 6.8
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 30 6.8
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 30 6.8
gi|56549111 optineurin [Homo sapiens] 30 8.9
gi|56549109 optineurin [Homo sapiens] 30 8.9
gi|20149572 optineurin [Homo sapiens] 30 8.9
gi|56549107 optineurin [Homo sapiens] 30 8.9
>gi|223941798 N-glycanase 1 isoform 2 [Homo sapiens]
Length = 636
Score = 1280 bits (3312), Expect = 0.0
Identities = 636/636 (100%), Positives = 636/636 (100%)
Query: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60
MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA
Sbjct: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60
Query: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120
FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH
Sbjct: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120
Query: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180
KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ
Sbjct: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180
Query: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240
HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE
Sbjct: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240
Query: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300
FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK
Sbjct: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300
Query: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTELQRTLSLKLTTLKEIGKTFLRISKR 360
LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTELQRTLSLKLTTLKEIGKTFLRISKR
Sbjct: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTELQRTLSLKLTTLKEIGKTFLRISKR 360
Query: 361 QKLIQVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRII 420
QKLIQVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRII
Sbjct: 361 QKLIQVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRII 420
Query: 421 VELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYN 480
VELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYN
Sbjct: 421 VELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYN 480
Query: 481 IVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECG 540
IVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECG
Sbjct: 481 IVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECG 540
Query: 541 SVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAEL 600
SVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAEL
Sbjct: 541 SVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAEL 600
Query: 601 SRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL 636
SRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL
Sbjct: 601 SRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL 636
>gi|21314690 N-glycanase 1 isoform 1 [Homo sapiens]
Length = 654
Score = 1209 bits (3127), Expect = 0.0
Identities = 614/655 (93%), Positives = 617/655 (94%), Gaps = 20/655 (3%)
Query: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60
MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA
Sbjct: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60
Query: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120
FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH
Sbjct: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120
Query: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180
KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ
Sbjct: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180
Query: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240
HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE
Sbjct: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240
Query: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300
FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK
Sbjct: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300
Query: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTE----------LQRTLSLKL------ 344
LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYT+ QR L
Sbjct: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCD 360
Query: 345 -TTLKEI--GKTFLRISKRQKLIQVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNK 401
L EI GK + K +VVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNK
Sbjct: 361 KPLLYEIGWGKKLSYVIAFSK-DEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNK 419
Query: 402 QRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKET 461
QRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKET
Sbjct: 420 QRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKET 479
Query: 462 LFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVY 521
LFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVY
Sbjct: 480 LFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMVY 539
Query: 522 LARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNS 581
LARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNS
Sbjct: 540 LARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTVEWKLRSDTAQVELTGDNS 599
Query: 582 LHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL 636
LHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL
Sbjct: 600 LHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHEENCLEIIIKFSDL 654
>gi|223941803 N-glycanase 1 isoform 3 [Homo sapiens]
Length = 612
Score = 1130 bits (2922), Expect = 0.0
Identities = 571/613 (93%), Positives = 575/613 (93%), Gaps = 20/613 (3%)
Query: 43 LRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 102
+RNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR
Sbjct: 1 MRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIR 60
Query: 103 DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 162
DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA
Sbjct: 61 DLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSA 120
Query: 163 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 222
STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN
Sbjct: 121 STVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 180
Query: 223 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 282
ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY
Sbjct: 181 ISDEDFLLLELLHWFKEEFFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHY 240
Query: 283 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTE------- 335
CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYT+
Sbjct: 241 CDACQFSNRFPRYNNPEKLLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVY 300
Query: 336 ---LQRTLSLKL-------TTLKEI--GKTFLRISKRQKLIQVVDVTWRYSCKHEEVIAR 383
QR L L EI GK + K +VVDVTWRYSCKHEEVIAR
Sbjct: 301 SPSQQRWLHCDACEDVCDKPLLYEIGWGKKLSYVIAFSK-DEVVDVTWRYSCKHEEVIAR 359
Query: 384 RTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISG 443
RTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISG
Sbjct: 360 RTKVKEALLRDTINGLNKQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISG 419
Query: 444 SVAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGV 503
SVAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGV
Sbjct: 420 SVAWRVARGEMGLQRKETLFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGV 479
Query: 504 WKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTV 563
WKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTV
Sbjct: 480 WKMESIFRKVETDWHMVYLARKEGSSFAYISWKFECGSVGLKVDSISIRTSSQTFQTGTV 539
Query: 564 EWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHE 623
EWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHE
Sbjct: 540 EWKLRSDTAQVELTGDNSLHSYADFSGATEVILEAELSRGDGDVAWQHTQLFRQSLNDHE 599
Query: 624 ENCLEIIIKFSDL 636
ENCLEIIIKFSDL
Sbjct: 600 ENCLEIIIKFSDL 612
>gi|223941808 N-glycanase 1 isoform 4 [Homo sapiens]
Length = 558
Score = 977 bits (2526), Expect = 0.0
Identities = 497/539 (92%), Positives = 501/539 (92%), Gaps = 20/539 (3%)
Query: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60
MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA
Sbjct: 1 MAAAALGSSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTA 60
Query: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120
FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH
Sbjct: 61 FSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSH 120
Query: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180
KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ
Sbjct: 121 KVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQ 180
Query: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240
HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE
Sbjct: 181 HVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDEDFLLLELLHWFKEE 240
Query: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300
FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK
Sbjct: 241 FFHWVNNVLCSKCGGQTRSRDRSLLPSDDELKWGAKEVEDHYCDACQFSNRFPRYNNPEK 300
Query: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTE----------LQRTLSLKL------ 344
LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYT+ QR L
Sbjct: 301 LLETRCGRCGEWANCFTLCCRAVGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCD 360
Query: 345 -TTLKEI--GKTFLRISKRQKLIQVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNK 401
L EI GK + K +VVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNK
Sbjct: 361 KPLLYEIGWGKKLSYVIAFSK-DEVVDVTWRYSCKHEEVIARRTKVKEALLRDTINGLNK 419
Query: 402 QRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKET 461
QRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKET
Sbjct: 420 QRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKET 479
Query: 462 LFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMV 520
LFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHM+
Sbjct: 480 LFIPCENEKISKQLHLCYNIVKDRYVRVSNNNQTISGWENGVWKMESIFRKVETDWHMI 538
>gi|41281571 synovial sarcoma, X breakpoint 2 interacting protein
[Homo sapiens]
Length = 614
Score = 37.7 bits (86), Expect = 0.033
Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Query: 401 KQRQLFLSENRRKELLQRIIVELVEFISPKTPKPGELGGRISGSVAWRVARGEMGLQRKE 460
+Q+Q+ + K++LQ++ E++ +SP+ KP E +G+V V L R+
Sbjct: 266 RQKQILMENAELKKVLQQMKKEMISLLSPQKKKPRERVDDSTGTVISDVEEDAGELSRES 325
Query: 461 TLFIPCE--NEKISKQLHLCYNIVKDRYVRVSN 491
+ CE E+++ + + I+K ++ N
Sbjct: 326 MWDLSCETVREQLTNSIRKQWRILKSHVEKLDN 358
>gi|13376854 UBX domain protein 6 [Homo sapiens]
Length = 441
Score = 37.4 bits (85), Expect = 0.042
Identities = 17/45 (37%), Positives = 26/45 (57%)
Query: 38 YADNILRNPNDEKYRSIRIGNTAFSTRLLPVRGAVECLFEMGFEE 82
Y DNI +P +EKYR I++ N F R+ + G E +GF++
Sbjct: 181 YLDNIHLHPEEEKYRKIKLQNKVFQERINCLEGTHEFFEAIGFQK 225
>gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]
Length = 848
Score = 35.8 bits (81), Expect = 0.12
Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 17/116 (14%)
Query: 113 LDGSNKSHKVKSSQQPAASTQLPTTPSS-----NPSGLNQHTRNRQGQSSDPPSASTVAA 167
L G+ K K+ +SQ+ + ++ ++ S NPS L Q TR+ G S+ S S+V+A
Sbjct: 135 LTGTAKPSKLLTSQEGSLGSEFISSYSLYQNTINPSTLGQFTRSVLGSST--VSKSSVSA 192
Query: 168 DSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINI 223
+I E L E P+ + + L ++ R + EK+ L+K I I
Sbjct: 193 SESIAEDL----------EEPSYKRERLTSFTDLQVIRAAPEKIVTKEDLEKNIEI 238
>gi|46276885 WD repeat domain 78 isoform 2 [Homo sapiens]
Length = 545
Score = 35.8 bits (81), Expect = 0.12
Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 17/116 (14%)
Query: 113 LDGSNKSHKVKSSQQPAASTQLPTTPSS-----NPSGLNQHTRNRQGQSSDPPSASTVAA 167
L G+ K K+ +SQ+ + ++ ++ S NPS L Q TR+ G S+ S S+V+A
Sbjct: 135 LTGTAKPSKLLTSQEGSLGSEFISSYSLYQNTINPSTLGQFTRSVLGSST--VSKSSVSA 192
Query: 168 DSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINI 223
+I E L E P+ + + L ++ R + EK+ L+K I I
Sbjct: 193 SESIAEDL----------EEPSYKRERLTSFTDLQVIRAAPEKIVTKEDLEKNIEI 238
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 34.7 bits (78), Expect = 0.28
Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 15/118 (12%)
Query: 104 LIAIERSSRLDGSNKSHKVKSS--QQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPS 161
L+A+++++ + + K++ QQP L S NP GL Q R P
Sbjct: 18 LLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQR---------PK 68
Query: 162 ASTVAADSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDK 219
VA L+ L N +HV V A ++ I V E ++++Q+K + ++K+++
Sbjct: 69 TRRVAP----LKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIER 122
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 34.3 bits (77), Expect = 0.36
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
Query: 76 FEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLP 135
+ + + E + H+ P S L+ D+ + ++ S + S + ++ ++S++
Sbjct: 1162 YSIKYNEEKRHVDQPIDYS---LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT 1218
Query: 136 TTPSSNPSGLNQ-HTRNRQGQSSDPPSASTVAADSAILEVLQS 177
+TPSSN NQ H + Q +S P A+T S E +Q+
Sbjct: 1219 STPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 34.3 bits (77), Expect = 0.36
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
Query: 76 FEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLP 135
+ + + E + H+ P S L+ D+ + ++ S + S + ++ ++S++
Sbjct: 1162 YSIKYNEEKRHVDQPIDYS---LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT 1218
Query: 136 TTPSSNPSGLNQ-HTRNRQGQSSDPPSASTVAADSAILEVLQS 177
+TPSSN NQ H + Q +S P A+T S E +Q+
Sbjct: 1219 STPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 34.3 bits (77), Expect = 0.36
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
Query: 76 FEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLP 135
+ + + E + H+ P S L+ D+ + ++ S + S + ++ ++S++
Sbjct: 1162 YSIKYNEEKRHVDQPIDYS---LKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENT 1218
Query: 136 TTPSSNPSGLNQ-HTRNRQGQSSDPPSASTVAADSAILEVLQS 177
+TPSSN NQ H + Q +S P A+T S E +Q+
Sbjct: 1219 STPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQT 1261
>gi|20070266 RAS-like GTP-binding protein REM [Homo sapiens]
Length = 298
Score = 33.9 bits (76), Expect = 0.47
Identities = 33/138 (23%), Positives = 60/138 (43%), Gaps = 15/138 (10%)
Query: 117 NKSHKVKSSQQPAASTQLPTTP--------SSNPSGLNQHTRNRQGQSSDPPSASTVAA- 167
N + K+ AST LP +P S+ PS +QH R Q S +PP+ A
Sbjct: 4 NTEQEAKTPLHRRASTPLPLSPRGHQPGRLSTVPSTQSQHPRLGQSASLNPPTQKPSPAP 63
Query: 168 -----DSAILEVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 222
+S+ E + V++ +P + + +LA + + +R E+L ++ +
Sbjct: 64 DDWSSESSDSEGSWEALYRVVLLGDPGVGKTSLASLFAGKQERDLHEQLGE-DVYERTLT 122
Query: 223 ISDEDFLLLELLHWFKEE 240
+ ED L+ + W E+
Sbjct: 123 VDGEDTTLVVVDTWEAEK 140
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 33.5 bits (75), Expect = 0.61
Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 10/114 (8%)
Query: 123 KSSQQPAASTQLPTTPSSNP---SGLNQHTRNRQGQSSDPPSASTVAADSAIL------- 172
+S Q AAS PT P P + L+Q + +GQ S+PPS S+ +S +
Sbjct: 915 RSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQ 974
Query: 173 EVLQSNIQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGINISDE 226
EV V E Q + ++ V++ K +S E R+ +L I ++
Sbjct: 975 EVKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEED 1028
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 32.7 bits (73), Expect = 1.0
Identities = 40/162 (24%), Positives = 62/162 (38%), Gaps = 21/162 (12%)
Query: 8 SSSGSASPAVAELCQNTPETFLEASKLLLTYADNILRNPNDEKYRSIRIGNTAFSTRLLP 67
SS G + P+ + +++P + + ++ ++ P R + TA ST
Sbjct: 1256 SSGGGSKPSYEAIPESSPPSGITSA------SNTTPGEPAASSSRPVAPSGTALSTTSSK 1309
Query: 68 VRGAVECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQ 127
+ L E L+FP + E L L R + D S K K+S
Sbjct: 1310 LETPPSKLGE---------LLFPSSLAGETLGSFSGL----RVGQADDSTKPTN-KASST 1355
Query: 128 PAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADS 169
STQ PT S PSG N G+ ++PP S+ S
Sbjct: 1356 SLTSTQ-PTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTS 1396
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 32.7 bits (73), Expect = 1.0
Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 96 EQLQKIRDLIAIERSSRLDG--SNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQ 153
+Q K ++ +A E+ L+ + S ++ SS++PA + + PS PS L+ + +
Sbjct: 651 KQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSSES 710
Query: 154 GQSSDPPSAS 163
G SS S+S
Sbjct: 711 GSSSSSGSSS 720
Score = 31.2 bits (69), Expect = 3.0
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 123 KSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEVLQSNIQHV 182
K +P + LP + S + +R+ + SSD S+ + + L LQ ++
Sbjct: 414 KMPDEPVEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLK-- 471
Query: 183 LVYENPALQEKALACIPVQELKRKSQEKLSRARKLDK 219
V+E A AL+ PV + K+K ++K +K DK
Sbjct: 472 AVHEQLA----ALSQAPVNKPKKKKEKKEKEKKKKDK 504
>gi|5174729 TSC22 domain family, member 1 isoform 2 [Homo sapiens]
Length = 144
Score = 32.0 bits (71), Expect = 1.8
Identities = 28/112 (25%), Positives = 53/112 (47%), Gaps = 26/112 (23%)
Query: 53 SIRIGNTAFSTRLLPVRGAVECLFEMGFEEGETHLIFPKKASVEQL-QKIRDLIAIERSS 111
S+R+ N++ ++ A++ E + ++HL++ + VE L ++I++LI E++S
Sbjct: 36 SVRLDNSSSGASVV----AIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELI--EKNS 89
Query: 112 RLDGSNKSHKVKSSQ-------------------QPAASTQLPTTPSSNPSG 144
+L+ N K +S QP +TQ P P+S SG
Sbjct: 90 QLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSG 141
>gi|183396804 Regulation of nuclear pre-mRNA domain containing 2
[Homo sapiens]
Length = 1461
Score = 32.0 bits (71), Expect = 1.8
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 5/88 (5%)
Query: 78 MGFEEGETHLIFPKK-ASVEQLQKIRDLIAIERSSRLDGSNK----SHKVKSSQQPAAST 132
MG EE ++ + +K A+ E + RD+ +E S D +K K K +++ A ST
Sbjct: 341 MGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVST 400
Query: 133 QLPTTPSSNPSGLNQHTRNRQGQSSDPP 160
+PT P+ N S + T ++ PP
Sbjct: 401 SVPTKPTENISKASSCTPVPVTMTATPP 428
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 30.8 bits (68), Expect = 4.0
Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 1/81 (1%)
Query: 91 KKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAAST-QLPTTPSSNPSGLNQHT 149
++ + EQ + ++ S+ L N +++++S QPA+ T LPT S+ G +
Sbjct: 1094 ERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSA 1153
Query: 150 RNRQGQSSDPPSASTVAADSA 170
R G S P A + A
Sbjct: 1154 AERGGPVSRSPGAPSAGEAEA 1174
>gi|23199971 T-cell activation Rho GTPase-activating protein isoform
a [Homo sapiens]
Length = 553
Score = 30.8 bits (68), Expect = 4.0
Identities = 31/149 (20%), Positives = 61/149 (40%), Gaps = 6/149 (4%)
Query: 20 LCQNTPETFLEASKLLLTYADNILRNPNDEK--YRSIRIGNTAFSTRLLPVRGAVECLFE 77
+ +N+ +++S L + N+L ND+ + + + N T V ++ FE
Sbjct: 41 ISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTL---VEFLIDNCFE 97
Query: 78 MGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTT 137
+ E H S+E D+ ++ S D ++ + SS ++ ++ P
Sbjct: 98 IFGENIPVHSSITSDDSLEHTDS-SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQV 156
Query: 138 PSSNPSGLNQHTRNRQGQSSDPPSASTVA 166
P + +GL+ + S P STVA
Sbjct: 157 PMATAAGLDSAGPQDAREVSPEPIVSTVA 185
>gi|21314774 T-cell activation Rho GTPase-activating protein isoform
b [Homo sapiens]
Length = 731
Score = 30.8 bits (68), Expect = 4.0
Identities = 31/149 (20%), Positives = 61/149 (40%), Gaps = 6/149 (4%)
Query: 20 LCQNTPETFLEASKLLLTYADNILRNPNDEK--YRSIRIGNTAFSTRLLPVRGAVECLFE 77
+ +N+ +++S L + N+L ND+ + + + N T V ++ FE
Sbjct: 219 ISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTL---VEFLIDNCFE 275
Query: 78 MGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTT 137
+ E H S+E D+ ++ S D ++ + SS ++ ++ P
Sbjct: 276 IFGENIPVHSSITSDDSLEHTDS-SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQV 334
Query: 138 PSSNPSGLNQHTRNRQGQSSDPPSASTVA 166
P + +GL+ + S P STVA
Sbjct: 335 PMATAAGLDSAGPQDAREVSPEPIVSTVA 363
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 30.4 bits (67), Expect = 5.2
Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 7/125 (5%)
Query: 107 IERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVA 166
+ER RL K K K+ +Q +PSS S +Q Q P S + ++
Sbjct: 802 VERERRLIRKEKVEKDKTDKQKRKGKV--HSPSSQSSETDQENEREQSPEK-PRSCNKLS 858
Query: 167 ADSAILEVLQSN----IQHVLVYENPALQEKALACIPVQELKRKSQEKLSRARKLDKGIN 222
+ A E + N + V++ + K + PV++LK K ++ LD+ +
Sbjct: 859 REKADKEGIAKNRLELMPCVVLTRVKEKEGKVIDHTPVEKLKAKLDNDTVKSSALDQKLQ 918
Query: 223 ISDED 227
+S +
Sbjct: 919 VSQTE 923
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 30.0 bits (66), Expect = 6.8
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 81 EEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSS 140
E ++ + P+K S +++ + + + ++R+ G KS V S +QPA+ T T S+
Sbjct: 119 EGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSA 178
Query: 141 NPSGLNQHTRNRQG 154
LN T + G
Sbjct: 179 ----LNTATEIKDG 188
>gi|16753207 ubiquilin 2 [Homo sapiens]
Length = 624
Score = 30.0 bits (66), Expect = 6.8
Identities = 48/190 (25%), Positives = 75/190 (39%), Gaps = 14/190 (7%)
Query: 13 ASPAVAELCQNTPE-TFLEASKLLLTYADNILRNPNDEKYRSIRIGNTAFSTRLLPVRGA 71
A+P + +L Q PE + L + ++ I RNP + +R + A S L + G
Sbjct: 207 ANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARNPAMMQ-EMMRNQDLALSN-LESIPGG 264
Query: 72 VECLFEMGFEEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAAS 131
L M + E L A+ EQ SS +G+ S P
Sbjct: 265 YNALRRMYTDIQEPML----NAAQEQFGGNPFASVGSSSSSGEGTQPSRTENRDPLPNPW 320
Query: 132 TQLPTTPSSNPSGLNQHTRNRQGQSSDPPSASTVAADSAILEV-----LQSNIQHVLVYE 186
P T SS + T + G SS + +TVAA + + + +QS +Q + E
Sbjct: 321 APPPATQSSATTSTTTSTGSGSGNSSSNATGNTVAAANYVASIFSTPGMQSLLQQIT--E 378
Query: 187 NPALQEKALA 196
NP L + L+
Sbjct: 379 NPQLIQNMLS 388
>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
Length = 1073
Score = 30.0 bits (66), Expect = 6.8
Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 22/94 (23%)
Query: 71 AVECLFEMGFEEGETHLIFPKKASVEQL-QKIRDLIAIERSSRLDGSNKSHKVKSSQ--- 126
A++ E + ++HL++ + VE L ++I++LI E++S+L+ N K +S
Sbjct: 979 AIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELI--EKNSQLEQENNLLKTLASPEQL 1036
Query: 127 ----------------QPAASTQLPTTPSSNPSG 144
QP +TQ P P+S SG
Sbjct: 1037 AQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSG 1070
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 30.0 bits (66), Expect = 6.8
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 81 EEGETHLIFPKKASVEQLQKIRDLIAIERSSRLDGSNKSHKVKSSQQPAASTQLPTTPSS 140
E ++ + P+K S +++ + + + ++R+ G KS V S +QPA+ T T S+
Sbjct: 84 EGQQSGTVSPQKQSAQKVIFKKKVSLLNIATRIMGGGKSGTVSSQKQPASKTASDKTDSA 143
Query: 141 NPSGLNQHTRNRQG 154
LN T + G
Sbjct: 144 ----LNTATEIKDG 153
>gi|56549111 optineurin [Homo sapiens]
Length = 577
Score = 29.6 bits (65), Expect = 8.9
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Query: 139 SSNPSGLNQHTR----NRQGQSSDPPSASTVAADSAILEVLQSNIQHVLVYENPALQEKA 194
S+ PS LN+ N++ + S + + A E +S + + + N LQE
Sbjct: 342 SAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHN 401
Query: 195 LACIPVQELKRKSQEKLSRA--RKLDKGINISDE 226
A ++EL RK EK+ RA ++L + + ++++
Sbjct: 402 NALKTIEELTRKESEKVDRAVLKELSEKLELAEK 435
>gi|56549109 optineurin [Homo sapiens]
Length = 577
Score = 29.6 bits (65), Expect = 8.9
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Query: 139 SSNPSGLNQHTR----NRQGQSSDPPSASTVAADSAILEVLQSNIQHVLVYENPALQEKA 194
S+ PS LN+ N++ + S + + A E +S + + + N LQE
Sbjct: 342 SAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHN 401
Query: 195 LACIPVQELKRKSQEKLSRA--RKLDKGINISDE 226
A ++EL RK EK+ RA ++L + + ++++
Sbjct: 402 NALKTIEELTRKESEKVDRAVLKELSEKLELAEK 435
>gi|20149572 optineurin [Homo sapiens]
Length = 577
Score = 29.6 bits (65), Expect = 8.9
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Query: 139 SSNPSGLNQHTR----NRQGQSSDPPSASTVAADSAILEVLQSNIQHVLVYENPALQEKA 194
S+ PS LN+ N++ + S + + A E +S + + + N LQE
Sbjct: 342 SAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHN 401
Query: 195 LACIPVQELKRKSQEKLSRA--RKLDKGINISDE 226
A ++EL RK EK+ RA ++L + + ++++
Sbjct: 402 NALKTIEELTRKESEKVDRAVLKELSEKLELAEK 435
>gi|56549107 optineurin [Homo sapiens]
Length = 577
Score = 29.6 bits (65), Expect = 8.9
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Query: 139 SSNPSGLNQHTR----NRQGQSSDPPSASTVAADSAILEVLQSNIQHVLVYENPALQEKA 194
S+ PS LN+ N++ + S + + A E +S + + + N LQE
Sbjct: 342 SAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHN 401
Query: 195 LACIPVQELKRKSQEKLSRA--RKLDKGINISDE 226
A ++EL RK EK+ RA ++L + + ++++
Sbjct: 402 NALKTIEELTRKESEKVDRAVLKELSEKLELAEK 435
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,528,885
Number of Sequences: 37866
Number of extensions: 1040146
Number of successful extensions: 3921
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 3894
Number of HSP's gapped (non-prelim): 51
length of query: 636
length of database: 18,247,518
effective HSP length: 109
effective length of query: 527
effective length of database: 14,120,124
effective search space: 7441305348
effective search space used: 7441305348
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.