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Search of human proteins with 223890205
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo
sapiens]
(442 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo s... 901 0.0
gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo sap... 863 0.0
gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo s... 764 0.0
gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo s... 545 e-155
gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo s... 496 e-140
gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo sa... 247 2e-65
gi|89993693 mouse double minute 2 homolog isoform MDM2d [Homo sa... 243 3e-64
gi|88702791 mouse double minute 4 homolog [Homo sapiens] 233 3e-61
gi|89993691 mouse double minute 2 homolog isoform MDM2e [Homo sa... 204 2e-52
gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo sa... 178 1e-44
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 53 5e-07
gi|223278368 neuralized-like [Homo sapiens] 42 0.001
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa... 41 0.002
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap... 41 0.002
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 41 0.002
gi|88759348 ring finger protein 219 [Homo sapiens] 40 0.006
gi|217416388 neuralized homolog 1B [Homo sapiens] 39 0.007
gi|58743365 ring finger protein 157 [Homo sapiens] 39 0.007
gi|38788243 myosin regulatory light chain interacting protein [H... 39 0.007
gi|39780588 TSR1, 20S rRNA accumulation [Homo sapiens] 39 0.007
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 39 0.009
gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo sap... 38 0.016
gi|210032580 SET domain containing 1B [Homo sapiens] 38 0.016
gi|5453567 craniofacial development protein 1 [Homo sapiens] 38 0.016
gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens] 37 0.027
gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens] 37 0.027
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 37 0.027
gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1 ... 37 0.027
gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo sa... 37 0.036
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 36 0.061
>gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo
sapiens]
Length = 442
Score = 901 bits (2329), Expect = 0.0
Identities = 442/442 (100%), Positives = 442/442 (100%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 121 ENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS 180
ENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS
Sbjct: 121 ENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS 180
Query: 181 EHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTD 240
EHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTD
Sbjct: 181 EHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTD 240
Query: 241 SFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLEN 300
SFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLEN
Sbjct: 241 SFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLEN 300
Query: 301 STQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQE 360
STQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQE
Sbjct: 301 STQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQE 360
Query: 361 DVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLK 420
DVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLK
Sbjct: 361 DVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLK 420
Query: 421 KRNKPCPVCRQPIQMIVLTYFP 442
KRNKPCPVCRQPIQMIVLTYFP
Sbjct: 421 KRNKPCPVCRQPIQMIVLTYFP 442
>gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo
sapiens]
Length = 497
Score = 863 bits (2229), Expect = 0.0
Identities = 438/497 (88%), Positives = 438/497 (88%), Gaps = 55/497 (11%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 121 ---------ENSDELSG------------------------------------------- 128
EN L G
Sbjct: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE 180
Query: 129 ---ERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGD 185
ERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGD
Sbjct: 181 LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGD 240
Query: 186 WLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEED 245
WLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEED
Sbjct: 241 WLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEED 300
Query: 246 PEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE 305
PEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE
Sbjct: 301 PEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE 360
Query: 306 EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEF 365
EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEF
Sbjct: 361 EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEF 420
Query: 366 EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP 425
EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP
Sbjct: 421 EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP 480
Query: 426 CPVCRQPIQMIVLTYFP 442
CPVCRQPIQMIVLTYFP
Sbjct: 481 CPVCRQPIQMIVLTYFP 497
>gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo
sapiens]
Length = 452
Score = 764 bits (1974), Expect = 0.0
Identities = 393/455 (86%), Positives = 408/455 (89%), Gaps = 16/455 (3%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE +
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEKI 60
Query: 61 F---YLGQYIMTKR-------LYDEKQQHIVYCSN--DLLGDL-FGVPSFSVKEHRKIYT 107
+ Y ++ ++ E + H+ S+ DL+ +L PS S R +
Sbjct: 61 YTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTS 120
Query: 108 MIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSEST 167
R +++ EENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSEST
Sbjct: 121 SRRR---AISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSEST 177
Query: 168 GTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVY 227
GTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVY
Sbjct: 178 GTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVY 237
Query: 228 QVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGK 287
QVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGK
Sbjct: 238 QVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGK 297
Query: 288 DKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQ 347
DKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQ
Sbjct: 298 DKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQ 357
Query: 348 PSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTG 407
PSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTG
Sbjct: 358 PSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTG 417
Query: 408 HLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 442
HLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 418 HLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 452
>gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo
sapiens]
Length = 444
Score = 545 bits (1404), Expect = e-155
Identities = 273/327 (83%), Positives = 276/327 (84%), Gaps = 47/327 (14%)
Query: 116 VNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDL 175
+++ EENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNP
Sbjct: 165 ISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNP-- 222
Query: 176 DAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAG 235
D D VYQVTVYQAG
Sbjct: 223 ---------------------------------------------DLDAGVYQVTVYQAG 237
Query: 236 ESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEK 295
ESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEK
Sbjct: 238 ESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEK 297
Query: 296 AKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSII 355
AKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSII
Sbjct: 298 AKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSII 357
Query: 356 YSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTC 415
YSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTC
Sbjct: 358 YSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTC 417
Query: 416 AKKLKKRNKPCPVCRQPIQMIVLTYFP 442
AKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 418 AKKLKKRNKPCPVCRQPIQMIVLTYFP 444
>gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo
sapiens]
Length = 295
Score = 496 bits (1276), Expect = e-140
Identities = 243/269 (90%), Positives = 243/269 (90%), Gaps = 26/269 (9%)
Query: 174 DLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQ 233
DLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDE
Sbjct: 53 DLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDE-------- 104
Query: 234 AGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEIS 293
DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEIS
Sbjct: 105 ------------------DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEIS 146
Query: 294 EKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSS 353
EKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSS
Sbjct: 147 EKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSS 206
Query: 354 IIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACF 413
IIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACF
Sbjct: 207 IIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACF 266
Query: 414 TCAKKLKKRNKPCPVCRQPIQMIVLTYFP 442
TCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 267 TCAKKLKKRNKPCPVCRQPIQMIVLTYFP 295
Score = 105 bits (263), Expect = 6e-23
Identities = 53/54 (98%), Positives = 53/54 (98%)
Query: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE L
Sbjct: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEDL 54
>gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo
sapiens]
Length = 249
Score = 247 bits (630), Expect = 2e-65
Identities = 132/181 (72%), Positives = 140/181 (77%), Gaps = 8/181 (4%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 121 ENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS 180
+ S R + S +++E+ E+ SSS PS +S
Sbjct: 121 SSDSGTSVSENRCHLEGGSDQKD--------LVQELQEEKPSSSHLVSRPSTSSRRRAIS 172
Query: 181 E 181
E
Sbjct: 173 E 173
Score = 168 bits (425), Expect = 1e-41
Identities = 85/108 (78%), Positives = 87/108 (80%), Gaps = 7/108 (6%)
Query: 335 QASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQG 394
Q + S S+PSTSS S E EETQDKEESVESSLPLNAIEPCVICQG
Sbjct: 149 QEEKPSSSHLVSRPSTSSRRRAIS-------ETEETQDKEESVESSLPLNAIEPCVICQG 201
Query: 395 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 442
RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 202 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 249
>gi|89993693 mouse double minute 2 homolog isoform MDM2d [Homo
sapiens]
Length = 172
Score = 243 bits (619), Expect = 3e-64
Identities = 122/132 (92%), Positives = 123/132 (93%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 121 ENSDELSGERQR 132
+ S R
Sbjct: 121 SSDSGTSVSENR 132
>gi|88702791 mouse double minute 4 homolog [Homo sapiens]
Length = 490
Score = 233 bits (593), Expect = 3e-61
Identities = 154/478 (32%), Positives = 243/478 (50%), Gaps = 87/478 (18%)
Query: 34 VRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFG 93
VRPK LLK+L + GAQ + +T+KEV+ YLGQYIM K+LYD+++QH+VYC DLLG+L G
Sbjct: 27 VRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLG 86
Query: 94 VPSFSVKEHRKIYTMIYRNLVVV------------------------NQQEENSDELSGE 129
SFSVK+ +Y M+ +NLV + +Q +++++E S
Sbjct: 87 RQSFSVKDPSPLYDMLRKNLVTLATATTDAAQTLALAQDHSMDIPSQDQLKQSAEESSTS 146
Query: 130 RQR------------------KRHKSDSI-SLSFDESLALCV-----------------I 153
R+R R D I +L+ DE+ L + +
Sbjct: 147 RKRTTEDDIPTLPTSEHKCIHSREDEDLIENLAQDETSRLDLGFEEWDVAGLPWWFLGNL 206
Query: 154 REICCERSSSSESTGTPSNPDLDAGVSEHSGD--WLDQDSVSDQFSVEFEVESLDSEDYS 211
R RS+ S T +N D+ + + D W +SVS+Q V +VE+ D+E
Sbjct: 207 RSNYTPRSNGS--TDLQTNQDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEAADTEQ-- 262
Query: 212 LSEEGQELSDEDDEVYQVTVYQAGESD------TDSFEEDPEISLADYWKCTSCNEMNPP 265
SEE ++SD+ V + G++D + S + D E++ D W+CT C + N P
Sbjct: 263 TSEEVGKVSDKK-------VIEVGKNDDLEDSKSLSDDTDVEVTSEDEWQCTECKKFNSP 315
Query: 266 LPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTI---VNDSR 322
+C RCWALR++W D K +S + EG DVPDC++TI V +
Sbjct: 316 SKRYCFRCWALRKDWY-SDCSKLTHSLSTSDITAIPEKENEGNDVPDCRRTISAPVVRPK 374
Query: 323 ESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLP 382
++ +++ + K+ S E D + S S I S E + + T E++E
Sbjct: 375 DAYIKKENSKLFDPCNSVEFLDLAHSSESQETISSMGEQLDNLSEQRTDT--ENMEDCQ- 431
Query: 383 LNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTY 440
N ++PC +C+ RP++G I+HG+TGHL+ CF CA++LKK CP+C++ IQ+++ +
Sbjct: 432 -NLLKPCSLCEKRPRDGNIIHGRTGHLVTCFHCARRLKKAGASCPICKKEIQLVIKVF 488
>gi|89993691 mouse double minute 2 homolog isoform MDM2e [Homo
sapiens]
Length = 179
Score = 204 bits (518), Expect = 2e-52
Identities = 101/104 (97%), Positives = 102/104 (98%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRK 104
FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE +
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEFER 104
Score = 175 bits (444), Expect = 6e-44
Identities = 81/81 (100%), Positives = 81/81 (100%)
Query: 362 VKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKK 421
VKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKK
Sbjct: 99 VKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKK 158
Query: 422 RNKPCPVCRQPIQMIVLTYFP 442
RNKPCPVCRQPIQMIVLTYFP
Sbjct: 159 RNKPCPVCRQPIQMIVLTYFP 179
>gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo
sapiens]
Length = 111
Score = 178 bits (451), Expect = 1e-44
Identities = 90/101 (89%), Positives = 94/101 (93%), Gaps = 1/101 (0%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKE 101
FYLGQYIMTKRLYDEKQQHIVYCSND +LF + S++E
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSND-CANLFPLVDLSIRE 100
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 53.1 bits (126), Expect = 5e-07
Identities = 56/264 (21%), Positives = 101/264 (38%), Gaps = 20/264 (7%)
Query: 117 NQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLD 176
N + SD G+ S S S D S SS S+S+ + S+ D D
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSS------------DSSDSDSSDSNSSSDSD 581
Query: 177 AGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGE 236
+ S+ S D D DS S DS D S S + + SD D + ++
Sbjct: 582 SSDSD-SSDSSDSDSSDSS-------NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633
Query: 237 SDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKA 296
SD+DS + + + +D + ++ + S + + + + + S+ +
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693
Query: 297 KLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIY 356
NS+++ + D D + +DS S ++D + S + S S+ SS
Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753
Query: 357 SSQEDVKEFEREETQDKEESVESS 380
S + ++ D +S +SS
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSS 777
Score = 48.1 bits (113), Expect = 2e-05
Identities = 58/267 (21%), Positives = 101/267 (37%), Gaps = 10/267 (3%)
Query: 117 NQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLD 176
N + N S + + SDS + S + + SS+ S + S+ D
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840
Query: 177 AGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQV-TVYQAG 235
+ S S D D DS S++ +S DS D S S + + SD ++ + +
Sbjct: 841 SSDSSDSSDGSDSDS-SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899
Query: 236 ESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEK 295
SD+DS + +D + +E + S N + N D + S
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSN---SSDNSNSSDSSN---SSDSSDSSDSSNS 953
Query: 296 AKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTS--SS 353
+ NS+ + D D + +DS S + + +S S +S + S S S SS
Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013
Query: 354 IIYSSQEDVKEFEREETQDKEESVESS 380
+S + + + D +S +SS
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Score = 47.8 bits (112), Expect = 2e-05
Identities = 59/282 (20%), Positives = 98/282 (34%), Gaps = 33/282 (11%)
Query: 117 NQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLD 176
+ ++SD S + + SDS S S + S S+ S + ++ D
Sbjct: 614 SDSSDSSDSKSDSSKSESDSSDSDSKS---------------DSSDSNSSDSSDNSDSSD 658
Query: 177 AGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGE 236
+ S +S D D SD S S DS D S S E SD D + +
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS 718
Query: 237 SDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKG---------- 286
S+++S + D S S + + S+ + ++ D
Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778
Query: 287 -------KDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQS 339
D S+ + NS+ + D D + +DS S N + +S S
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Query: 340 QESEDYSQPSTSSSIIYSSQED-VKEFEREETQDKEESVESS 380
+S D S S S S++ D + ++ D S +SS
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880
Score = 37.0 bits (84), Expect = 0.036
Identities = 51/229 (22%), Positives = 84/229 (36%), Gaps = 30/229 (13%)
Query: 165 ESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQF-SVEFEVESLDSEDYSLSEEGQELSDED 223
E G S P G S D S SD + S +F+ +S+ +D + S+E D +
Sbjct: 424 EGPGQKSEPGNKVGHSNTGSD-----SNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDAN 478
Query: 224 DEVYQVTV------YQAGES-------DTDSFEEDPEISLADYWKCTSCNEMNPPLPSHC 270
E + Y + ES D+ E+D S +D S N +
Sbjct: 479 SESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDND 538
Query: 271 NRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEEND 330
KGK S+ + NS+ + + D +DS S + +D
Sbjct: 539 KS---------DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD 589
Query: 331 DKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVES 379
+ +S S S D S S SS S D + + + ++ + +S +S
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSKSDSSKSESDSSDS 636
Score = 33.1 bits (74), Expect = 0.52
Identities = 41/174 (23%), Positives = 64/174 (36%), Gaps = 34/174 (19%)
Query: 159 ERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQE 218
E + S G+PS D E SGD D+++ + + DS + S +EGQ+
Sbjct: 235 EDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGK----------DSSNNSKGQEGQD 284
Query: 219 LSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRE 278
EDD + G++ DPE K NE++ S
Sbjct: 285 HGKEDDHDSSI-----GQNSDSKEYYDPE------GKEDPHNEVDGDKTSKSEE----NS 329
Query: 279 NWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDK 332
+PED G + E ++K S + E I +S V ++ DK
Sbjct: 330 AGIPEDNGSQRIEDTQKLNHRESKRVE---------NRITKESETHAVGKSQDK 374
>gi|223278368 neuralized-like [Homo sapiens]
Length = 574
Score = 42.0 bits (97), Expect = 0.001
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 11/70 (15%)
Query: 380 SLPLNAIEP--------CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKR-NKPCPVCR 430
SLP + + P C IC + I GH+ C+ C +LKK + CP+CR
Sbjct: 504 SLPESPVTPGLGQWSDECTICYEHAVDTVIY--TCGHMCLCYACGLRLKKALHACCPICR 561
Query: 431 QPIQMIVLTY 440
+PI+ I+ TY
Sbjct: 562 RPIKDIIKTY 571
>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 359 QEDVKEFEREETQDKEESVESSLP-LNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAK 417
Q+D+K E+ D VE L L C +C K IV GHL+ C CA
Sbjct: 528 QQDIKYIPTEDVSDLP--VEEQLRRLQEERTCKVCMD--KEVSIVFIPCGHLVVCKDCAP 583
Query: 418 KLKKRNKPCPVCRQPIQMIVLTY 440
L+K CP+CR I+ V T+
Sbjct: 584 SLRK----CPICRSTIKGTVRTF 602
>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 359 QEDVKEFEREETQDKEESVESSLP-LNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAK 417
Q+D+K E+ D VE L L C +C K IV GHL+ C CA
Sbjct: 528 QQDIKYIPTEDVSDLP--VEEQLRRLQEERTCKVCMD--KEVSIVFIPCGHLVVCKDCAP 583
Query: 418 KLKKRNKPCPVCRQPIQMIVLTY 440
L+K CP+CR I+ V T+
Sbjct: 584 SLRK----CPICRSTIKGTVRTF 602
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 40.8 bits (94), Expect = 0.002
Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 2/123 (1%)
Query: 129 ERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHS-GDWL 187
+++RK+ S ES+ LC E+ + E T P P+ + + DW
Sbjct: 448 DKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWE 507
Query: 188 DQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESD-TDSFEEDP 246
S + VE ++ ++ EE +E +E+DE + + GES+ ++ EED
Sbjct: 508 AMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDE 567
Query: 247 EIS 249
++S
Sbjct: 568 KVS 570
>gi|88759348 ring finger protein 219 [Homo sapiens]
Length = 726
Score = 39.7 bits (91), Expect = 0.006
Identities = 40/160 (25%), Positives = 61/160 (38%), Gaps = 9/160 (5%)
Query: 121 ENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAG-- 178
+N D S E + IS E LC+ + + RS T T S +DA
Sbjct: 476 QNLDFESSEGNTIANSVGEISSKLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYL 535
Query: 179 --VSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTV--YQA 234
+SE + D+ + F +SLD + S S +G E +E D++ + T
Sbjct: 536 DKISELDSMMSESDNSKSPCNNGF--KSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSK 593
Query: 235 GESDTDSFEEDPEISLADYWKCT-SCNEMNPPLPSHCNRC 273
G D E E ++ + S EMN H + C
Sbjct: 594 GSLTNDQLENGSEWKPTSFFLLSPSDQEMNEDFSLHSSSC 633
Score = 28.9 bits (63), Expect = 9.8
Identities = 15/45 (33%), Positives = 19/45 (42%), Gaps = 3/45 (6%)
Query: 389 CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPI 433
C IC G+ + I + + C C K N CP CR PI
Sbjct: 18 CHICLGKVRQPVIC---INNHVFCSICIDLWLKNNSQCPACRVPI 59
>gi|217416388 neuralized homolog 1B [Homo sapiens]
Length = 555
Score = 39.3 bits (90), Expect = 0.007
Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 17/120 (14%)
Query: 340 QESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRP--- 396
Q S + PS S S + F ++ ES + P + + P V P
Sbjct: 436 QSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEP 495
Query: 397 ---KNG-CIV--HGKT-------GHLMACFTCAKKLKKRNKPC-PVCRQPIQMIVLTYFP 442
KNG C V G+ GH+ C +C +LK++ + C P+CR+PI+ ++ Y P
Sbjct: 496 AGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP 555
>gi|58743365 ring finger protein 157 [Homo sapiens]
Length = 679
Score = 39.3 bits (90), Expect = 0.007
Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 347 QPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKT 406
Q + Y QE + TQD + + E + N+ E CV+C ++ I+ +
Sbjct: 237 QKQVVDGVSYLLQEIYGIENKYNTQDSKVA-EDEVSDNSAE-CVVCLSDVRDTLILPCR- 293
Query: 407 GHLMACFTCAKKLKKRNKPCPVCRQPIQMIV 437
HL C TCA L+ + CP+CR P + ++
Sbjct: 294 -HLCLCNTCADTLRYQANNCPICRLPFRALL 323
>gi|38788243 myosin regulatory light chain interacting protein [Homo
sapiens]
Length = 445
Score = 39.3 bits (90), Expect = 0.007
Identities = 32/136 (23%), Positives = 60/136 (44%), Gaps = 15/136 (11%)
Query: 308 FDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQ-PSTSSSIIYSSQEDVKEFE 366
FD+ K + + +R + N + S++ +S +S S+ SS+ SS E + +
Sbjct: 313 FDIKRTSKEVYDHARRALY--NAGVVDLVSRNNQSPSHSPLKSSESSMNCSSCEGLSCQQ 370
Query: 367 REETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPC 426
Q+K ++ ++ C++C N GH + C +CA +L+ C
Sbjct: 371 TRVLQEKLRKLKEAML------CMVCCEEEINSTFC--PCGHTVCCESCAAQLQS----C 418
Query: 427 PVCRQPIQMIVLTYFP 442
PVCR ++ + Y P
Sbjct: 419 PVCRSRVEHVQHVYLP 434
>gi|39780588 TSR1, 20S rRNA accumulation [Homo sapiens]
Length = 804
Score = 39.3 bits (90), Expect = 0.007
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 178 GVSEHSGDW-LDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGE 236
G S + +W LD S S E+E + ++ ED+ E E S+E++E +T+ ++
Sbjct: 396 GTSSYQAEWILDGGSQSGGEGDEYEYDDMEHEDFMEEESQDESSEEEEEYETMTIGESVH 455
Query: 237 SD--TDSFEEDPEISLADYWKCTSCNEMNP 264
D +E+ E + + +K EM P
Sbjct: 456 DDLYDKKVDEEAEAKMLEKYKQERLEEMFP 485
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 38.9 bits (89), Expect = 0.009
Identities = 63/273 (23%), Positives = 104/273 (38%), Gaps = 49/273 (17%)
Query: 125 ELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSG 184
+ E +RK S S S S E+ A S S ++G+ S+ D + S
Sbjct: 11 DADSEAERKDSDSGSDSDSDQENAA------------SGSNASGSESDQDERGDSGQPSN 58
Query: 185 DWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSD-EDDEVYQVTVYQAGESDTDSFE 243
L D D+ + SE E E SD ED++ V + E+ D +
Sbjct: 59 KELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDED 118
Query: 244 EDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKG-------------KDKG 290
E + +E +H + E W EDK +++
Sbjct: 119 EGHRSDGGSHHSEAEGSEK-----AHSDD-----EKWGREDKSDQSDDEKIQNSDDEERA 168
Query: 291 EISEKAKLENSTQAEEGFDVPDCKKT-IVNDSRESCVEE----NDDKITQAS----QSQE 341
+ S++ KL+NS E+ + D ++ + +D R+ EE +DD+ AS + Q
Sbjct: 169 QGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQN 228
Query: 342 SEDYSQPSTSSSIIYSSQEDVKEFEREETQDKE 374
S+D QP S + +D ER + D+E
Sbjct: 229 SDDEEQPQLSDEEKMQNSDD----ERPQASDEE 257
Score = 31.2 bits (69), Expect = 2.0
Identities = 41/183 (22%), Positives = 69/183 (37%), Gaps = 28/183 (15%)
Query: 117 NQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLD 176
N +E +LS + +++ + + + S DE R + + +++ P L
Sbjct: 187 NTDDEERPQLSDDERQQLSEEEKAN-SDDE-------RPVASDNDDEKQNSDDEEQPQLS 238
Query: 177 AGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQ--A 234
+ D Q S E S D E+ E SD +DEV ++ A
Sbjct: 239 -----DEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIA 293
Query: 235 GESDTDSFEEDPE--------ISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKG 286
+S+ DS E P+ AD S E PP P + EN LP+D+
Sbjct: 294 SDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQ-----PVDENGLPQDQQ 348
Query: 287 KDK 289
+++
Sbjct: 349 EEE 351
>gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo
sapiens]
Length = 618
Score = 38.1 bits (87), Expect = 0.016
Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 26/146 (17%)
Query: 295 KAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSI 354
K K + QA E D K + ++C++E D + Y ++
Sbjct: 497 KQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTL-----------YKNLFVDKNM 545
Query: 355 IYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFT 414
Y EDV EE + L C +C K +V GHL+ C
Sbjct: 546 KYIPTEDVSGLSLEEQLRR---------LQEERTCKVCMD--KEVSVVFIPCGHLVVCQE 594
Query: 415 CAKKLKKRNKPCPVCRQPIQMIVLTY 440
CA L+K CP+CR I+ V T+
Sbjct: 595 CAPSLRK----CPICRGIIKGTVRTF 616
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 38.1 bits (87), Expect = 0.016
Identities = 49/195 (25%), Positives = 80/195 (41%), Gaps = 23/195 (11%)
Query: 188 DQDSVSDQFSVEFEVESLDSE-DYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSF-EED 245
DQ + SV+ E E + E D +++ EL+ D + V A + DS EED
Sbjct: 977 DQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEED 1036
Query: 246 PEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEIS---EKAKLENST 302
+ SL++ + T E E +D D+ E E L ++
Sbjct: 1037 EKESLSEEQESTEEEEEAEEEEE---------EEDDDDDDSDDRDESENDDEDTALSEAS 1087
Query: 303 QAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDV 362
+ +EG + +IV E+ T +S+S ES ++ S SS +E+V
Sbjct: 1088 EKDEGDSDEEETVSIVTSKAEA---------TSSSESSESSEFESSSESSPSSSEDEEEV 1138
Query: 363 KEFEREETQDKEESV 377
E EE +++EE V
Sbjct: 1139 VAREEEEEEEEEEMV 1153
Score = 37.4 bits (85), Expect = 0.027
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
Query: 284 DKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVE-ENDDKITQASQ-SQE 341
D G ++ E ++ + ST+ EE + + ++ +D + E ENDD+ T S+ S++
Sbjct: 1030 DSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEK 1089
Query: 342 SEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESS 380
E S + SI+ S E E E+ + E S ESS
Sbjct: 1090 DEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESS 1128
>gi|5453567 craniofacial development protein 1 [Homo sapiens]
Length = 299
Score = 38.1 bits (87), Expect = 0.016
Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 10/169 (5%)
Query: 202 VESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNE 261
+E DSED+S SEE ++ E + V + + D EE + + K S
Sbjct: 1 MEEFDSEDFSTSEEDEDYVPSGGEYSEDDVNELVKEDEVDGEEQTQKTQGKKRKAQS--- 57
Query: 262 MNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDS 321
+P+ R L E+ + E S + +++ + E+G D +K ++
Sbjct: 58 ----IPARKRRQGGLSLEEEEEEDANSESEGSSSEEEDDAAEQEKGIGSEDARKKKEDEL 113
Query: 322 RESCVEE--NDDKITQASQSQESEDYSQPSTSSSIIYSSQ-EDVKEFER 367
S + + K+ ++Q ++ E+ + S+S ++ + + E KE E+
Sbjct: 114 WASFLNDVGPKSKVPPSTQVKKGEETEETSSSKLLVKAEELEKPKETEK 162
>gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens]
Length = 373
Score = 37.4 bits (85), Expect = 0.027
Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 17/75 (22%)
Query: 358 SQEDVKEF-EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCA 416
++E+ K + ER + QD+E+ + ++A+ CV+ + GH++ C C
Sbjct: 304 NEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLE------------CGHMVTCTKCG 351
Query: 417 KKLKKRNKPCPVCRQ 431
K++ + CP+CRQ
Sbjct: 352 KRMSE----CPICRQ 362
>gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens]
Length = 372
Score = 37.4 bits (85), Expect = 0.027
Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 17/75 (22%)
Query: 358 SQEDVKEF-EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCA 416
++E+ K + ER + QD+E+ + ++A+ CV+ + GH++ C C
Sbjct: 303 NEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLE------------CGHMVTCTKCG 350
Query: 417 KKLKKRNKPCPVCRQ 431
K++ + CP+CRQ
Sbjct: 351 KRMSE----CPICRQ 361
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 37.4 bits (85), Expect = 0.027
Identities = 62/296 (20%), Positives = 123/296 (41%), Gaps = 58/296 (19%)
Query: 117 NQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCER----SSSSESTG---- 168
N+ ++ + S E ++ + KS S S + ES + + C ++ S +S+ T
Sbjct: 156 NEADKTPLKSSHENEQSK-KSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFL 214
Query: 169 -TPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEG--QELSDEDDE 225
T +NP D S+ S D + + + +V+F + S+D S++ + + S + +
Sbjct: 215 HTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSK 274
Query: 226 VYQVTVYQAGESDT--------DSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALR 277
Y + + + DT D+ ED + + D K ++
Sbjct: 275 NYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKK--------------------VK 314
Query: 278 ENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSR--------ESCVEEN 329
+N +DK KD + +E E+ +E D KK + D + ES E+
Sbjct: 315 KNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTES 374
Query: 330 DD---------KITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEES 376
D + +AS++ + + ++ T S+ S E KE +++E +DK++S
Sbjct: 375 GDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELES-KESQKDEKKDKKDS 429
>gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1
[Homo sapiens]
Length = 352
Score = 37.4 bits (85), Expect = 0.027
Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 18/85 (21%)
Query: 363 KEFEREETQ-------DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTC 415
+EF+ E Q + ES++S+ CV+C K+ V + GH+ +C C
Sbjct: 277 EEFQEHEAQLLSRAKPEDRESLKSA--------CVVCLSSFKS--CVFLECGHVCSCTEC 326
Query: 416 AKKLKKRNKPCPVCRQPIQMIVLTY 440
+ L + K CP+CRQ I ++ Y
Sbjct: 327 YRALPEPKK-CPICRQAITRVIPLY 350
>gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo
sapiens]
Length = 497
Score = 37.0 bits (84), Expect = 0.036
Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 8/100 (8%)
Query: 332 KITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ-DKEESVESSLP-LNAIEPC 389
KI + +Y + + ++Q+D + E +T KE S E L L + C
Sbjct: 391 KIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLC 450
Query: 390 VICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVC 429
IC R N IV GHL+ C CA+ + K CP+C
Sbjct: 451 KICMDR--NIAIVFVPCGHLVTCKQCAEAVDK----CPMC 484
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 36.2 bits (82), Expect = 0.061
Identities = 35/188 (18%), Positives = 76/188 (40%), Gaps = 9/188 (4%)
Query: 194 DQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADY 253
++ E E E+ + S E S D T + E + + EE P +S
Sbjct: 1227 EEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPET--ETKEPEVEEEEEKPRVSEEQR 1284
Query: 254 WKCTSCNEMNPPLPSHCNRC---WALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDV 310
E+ P P A ++ +D+ E ++K +LE E+ +
Sbjct: 1285 QSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEE 1344
Query: 311 PDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREET 370
P +++ ++ + ++++ +KI +++ + QPS +S++ ++ E++
Sbjct: 1345 PGVQESFLDAN----MQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDS 1400
Query: 371 QDKEESVE 378
KEE +E
Sbjct: 1401 HTKEELIE 1408
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,769,494
Number of Sequences: 37866
Number of extensions: 858705
Number of successful extensions: 4147
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 203
Number of HSP's that attempted gapping in prelim test: 3593
Number of HSP's gapped (non-prelim): 651
length of query: 442
length of database: 18,247,518
effective HSP length: 105
effective length of query: 337
effective length of database: 14,271,588
effective search space: 4809525156
effective search space used: 4809525156
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.