Guide to the Human Genome
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Search of human proteins with 223718151

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223718151 leucine rich transmembrane and 0-methyltransferase
domain containing isoform 2 [Homo sapiens]
         (158 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223718151 leucine rich transmembrane and 0-methyltransferase ...   322   6e-89
gi|21687175 leucine rich transmembrane and 0-methyltransferase d...   296   6e-81
gi|206725447 leucine rich repeat containing 23 isoform a [Homo s...    55   2e-08
gi|42542396 leucine rich repeat containing 23 isoform a [Homo sa...    55   2e-08
gi|39930571 leucine rich repeat containing 56 [Homo sapiens]           44   6e-05
gi|66472382 nischarin [Homo sapiens]                                   43   1e-04
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s...    42   2e-04
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s...    42   2e-04
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s...    42   2e-04
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s...    42   2e-04
gi|109150416 peroxidasin [Homo sapiens]                                40   8e-04
gi|4826651 hypothetical protein LOC755 [Homo sapiens]                  39   0.002
gi|157785649 leucine-rich repeats and IQ motif containing 3 [Hom...    39   0.002
gi|164607156 axonemal dynein light chain 1 [Homo sapiens]              38   0.003
gi|239752702 PREDICTED: leucine rich repeat containing 38, parti...    37   0.009
gi|239747236 PREDICTED: leucine rich repeat containing 38 [Homo ...    37   0.009
gi|239741057 PREDICTED: leucine rich repeat containing 38 [Homo ...    37   0.009
gi|46397373 leucine rich repeat containing 20 isoform 2 [Homo sa...    37   0.009
gi|46397369 leucine rich repeat containing 20 isoform 1 [Homo sa...    36   0.012
gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo s...    36   0.016
gi|239752518 PREDICTED: similar to leucine rich repeat containin...    36   0.016
gi|37221175 PH domain and leucine rich repeat protein phosphatas...    36   0.016
gi|55743114 leucine rich repeat containing 49 [Homo sapiens]           36   0.016
gi|15529980 leucine rich repeat containing 46 [Homo sapiens]           36   0.016
gi|148664188 leucine rich repeat containing 43 isoform 2 [Homo s...    35   0.027
gi|148664213 leucine rich repeat containing 43 isoform 1 [Homo s...    35   0.027
gi|63003903 leucine rich repeat containing 10 [Homo sapiens]           35   0.035
gi|218931217 leucine rich repeat containing 61 [Homo sapiens]          35   0.035
gi|13027616 leucine rich repeat containing 61 [Homo sapiens]           35   0.035
gi|21361633 leucine rich repeat containing 40 [Homo sapiens]           35   0.035

>gi|223718151 leucine rich transmembrane and 0-methyltransferase
           domain containing isoform 2 [Homo sapiens]
          Length = 158

 Score =  322 bits (826), Expect = 6e-89
 Identities = 158/158 (100%), Positives = 158/158 (100%)

Query: 1   MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNV 60
           MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNV
Sbjct: 1   MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNV 60

Query: 61  LNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEV 120
           LNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEV
Sbjct: 61  LNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEV 120

Query: 121 NKLAVLPRLRSLTLHGNPMEEEKGYRVPGSVEMPHRPP 158
           NKLAVLPRLRSLTLHGNPMEEEKGYRVPGSVEMPHRPP
Sbjct: 121 NKLAVLPRLRSLTLHGNPMEEEKGYRVPGSVEMPHRPP 158


>gi|21687175 leucine rich transmembrane and 0-methyltransferase
           domain containing isoform 1 [Homo sapiens]
          Length = 192

 Score =  296 bits (757), Expect = 6e-81
 Identities = 146/146 (100%), Positives = 146/146 (100%)

Query: 1   MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNV 60
           MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNV
Sbjct: 1   MNKRDYMNTSVQEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNV 60

Query: 61  LNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEV 120
           LNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEV
Sbjct: 61  LNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEV 120

Query: 121 NKLAVLPRLRSLTLHGNPMEEEKGYR 146
           NKLAVLPRLRSLTLHGNPMEEEKGYR
Sbjct: 121 NKLAVLPRLRSLTLHGNPMEEEKGYR 146


>gi|206725447 leucine rich repeat containing 23 isoform a [Homo
           sapiens]
          Length = 343

 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 5/142 (3%)

Query: 16  LDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQL- 74
           L+    SIH++  L   +P   +        G  L  +L +N   L +L     +  ++ 
Sbjct: 160 LNLKGNSIHMVTGL---DPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVE 216

Query: 75  -LEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLT 133
            LE   NL  + L  N + ++        +L  L L GN +  LGE+ KL  LP+LR+L 
Sbjct: 217 GLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALV 276

Query: 134 LHGNPMEEEKGYRVPGSVEMPH 155
           L  NP  +E  YR    V+MP+
Sbjct: 277 LLDNPCTDETSYRQEALVQMPY 298


>gi|42542396 leucine rich repeat containing 23 isoform a [Homo
           sapiens]
          Length = 343

 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 5/142 (3%)

Query: 16  LDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQL- 74
           L+    SIH++  L   +P   +        G  L  +L +N   L +L     +  ++ 
Sbjct: 160 LNLKGNSIHMVTGL---DPEKLISLHTVELRGNQLESTLGINLPKLKNLYLAQNMLKKVE 216

Query: 75  -LEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLT 133
            LE   NL  + L  N + ++        +L  L L GN +  LGE+ KL  LP+LR+L 
Sbjct: 217 GLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALV 276

Query: 134 LHGNPMEEEKGYRVPGSVEMPH 155
           L  NP  +E  YR    V+MP+
Sbjct: 277 LLDNPCTDETSYRQEALVQMPY 298


>gi|39930571 leucine rich repeat containing 56 [Homo sapiens]
          Length = 542

 Score = 43.9 bits (102), Expect = 6e-05
 Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 9/86 (10%)

Query: 52  QSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHG 111
           Q LWL    L DL     + +        L  +  S+N+++ + P L     L VL L G
Sbjct: 119 QVLWLARCGLADLDGIASLPA--------LKELYASYNNISDLSP-LCLLEQLEVLDLEG 169

Query: 112 NSIQRLGEVNKLAVLPRLRSLTLHGN 137
           NS++ LG+V  L + PRL  LTL GN
Sbjct: 170 NSVEDLGQVRYLQLCPRLAMLTLEGN 195


>gi|66472382 nischarin [Homo sapiens]
          Length = 1504

 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 27/77 (35%), Positives = 44/77 (57%), Gaps = 3/77 (3%)

Query: 75  LEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTL 134
           L+H  NL  +DLS+N L+S++ + T   N+  L L GN ++ L  ++KL     L +L L
Sbjct: 328 LQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLY---SLVNLDL 384

Query: 135 HGNPMEEEKGYRVPGSV 151
             N +E+ +  R  GS+
Sbjct: 385 RDNRIEQMEEVRSIGSL 401


>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
           sapiens]
          Length = 457

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 12/89 (13%)

Query: 52  QSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHG 111
           + L L+NN++  +          LE+  +L W+DLSFN++ +I+  L T  NL  L L  
Sbjct: 68  RKLQLDNNIIEKIEG--------LENLAHLVWLDLSFNNIETIEG-LDTLVNLEDLSLFN 118

Query: 112 NSIQRLGEVNKLAVLPRLRSLTLHGNPME 140
           N   R+ +++ L  L +L+ L+L  N ++
Sbjct: 119 N---RISKIDSLDALVKLQVLSLGNNRID 144


>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
           sapiens]
          Length = 457

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 12/89 (13%)

Query: 52  QSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHG 111
           + L L+NN++  +          LE+  +L W+DLSFN++ +I+  L T  NL  L L  
Sbjct: 68  RKLQLDNNIIEKIEG--------LENLAHLVWLDLSFNNIETIEG-LDTLVNLEDLSLFN 118

Query: 112 NSIQRLGEVNKLAVLPRLRSLTLHGNPME 140
           N   R+ +++ L  L +L+ L+L  N ++
Sbjct: 119 N---RISKIDSLDALVKLQVLSLGNNRID 144


>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
           sapiens]
          Length = 523

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 12/89 (13%)

Query: 52  QSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHG 111
           + L L+NN++  +          LE+  +L W+DLSFN++ +I+  L T  NL  L L  
Sbjct: 68  RKLQLDNNIIEKIEG--------LENLAHLVWLDLSFNNIETIEG-LDTLVNLEDLSLFN 118

Query: 112 NSIQRLGEVNKLAVLPRLRSLTLHGNPME 140
           N   R+ +++ L  L +L+ L+L  N ++
Sbjct: 119 N---RISKIDSLDALVKLQVLSLGNNRID 144


>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
           sapiens]
          Length = 523

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 12/89 (13%)

Query: 52  QSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHG 111
           + L L+NN++  +          LE+  +L W+DLSFN++ +I+  L T  NL  L L  
Sbjct: 68  RKLQLDNNIIEKIEG--------LENLAHLVWLDLSFNNIETIEG-LDTLVNLEDLSLFN 118

Query: 112 NSIQRLGEVNKLAVLPRLRSLTLHGNPME 140
           N   R+ +++ L  L +L+ L+L  N ++
Sbjct: 119 N---RISKIDSLDALVKLQVLSLGNNRID 144


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 40.0 bits (92), Expect = 8e-04
 Identities = 33/99 (33%), Positives = 49/99 (49%), Gaps = 12/99 (12%)

Query: 53  SLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSID-PVLTTFFNLSVLYLHG 111
           +L LNNN +       ++ S   E  ENL ++ L  N++ SID        +L  LYLH 
Sbjct: 90  TLLLNNNQIK------RIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGLASLEQLYLHF 143

Query: 112 NSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRVPGS 150
           N I+ L + +    LP+L  L LH N +     + VPG+
Sbjct: 144 NQIETL-DPDSFQHLPKLERLFLHNNRIT----HLVPGT 177


>gi|4826651 hypothetical protein LOC755 [Homo sapiens]
          Length = 256

 Score = 38.9 bits (89), Expect = 0.002
 Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 61  LNDLRDFNQVASQLLE-----HPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQ 115
           L+ +R  N   S+L +        +L  I LS N +++++PV +    LS LYL  N I 
Sbjct: 17  LHSVRKLNCWGSRLTDISICQEMPSLEVITLSVNSISTLEPV-SRCQRLSELYLRRNRIP 75

Query: 116 RLGEVNKLAVLPRLRSLTLHGNP 138
            L E+  L  LPRLR L L  NP
Sbjct: 76  SLAELFYLKGLPRLRVLWLAENP 98


>gi|157785649 leucine-rich repeats and IQ motif containing 3 [Homo
           sapiens]
          Length = 624

 Score = 38.9 bits (89), Expect = 0.002
 Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 14/94 (14%)

Query: 57  NNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFN----LSVLYLHGN 112
           +NN + D+          L+    L  +DL  N + S+    T F+N    L +LYLH N
Sbjct: 58  SNNFITDIHP--------LQSCIKLIKLDLHGNQIKSLPN--TKFWNGLKNLKLLYLHDN 107

Query: 113 SIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYR 146
              +L  +  L+  P L +LT+   P+  +KGYR
Sbjct: 108 GFAKLKNICVLSACPTLIALTMFDCPVSLKKGYR 141


>gi|164607156 axonemal dynein light chain 1 [Homo sapiens]
          Length = 190

 Score = 38.1 bits (87), Expect = 0.003
 Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 8/131 (6%)

Query: 12  QEPPLDYSFRSIHVIQDLVNEEPRTGLRPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVA 71
           Q PP++    S+ ++ +       T       + +G    + L L  N + +L     V 
Sbjct: 33  QIPPIEKMDASLSMLANCEKLSLSTNCIEKIANLNGLKNLRILSLGRNNIKNLNGLEAVG 92

Query: 72  SQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRS 131
             L E      WI  +F +      ++     L +LY+  N ++   E  KLA LP L  
Sbjct: 93  DTLEE-----LWISYNFIEKLKGIHIMK---KLKILYMSNNLVKDWAEFVKLAELPCLED 144

Query: 132 LTLHGNPMEEE 142
           L   GNP+EE+
Sbjct: 145 LVFVGNPLEEK 155


>gi|239752702 PREDICTED: leucine rich repeat containing 38, partial
           [Homo sapiens]
          Length = 254

 Score = 36.6 bits (83), Expect = 0.009
 Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 66  DFNQVASQLLEHPENLAWIDLSFNDLTSI-DPVLTTFFNLSVLYLHGNSIQRLGEVNKLA 124
           +  Q+ +        L  + L+ N+L  + +    T  +L VL L+ N+++ L  V  LA
Sbjct: 75  NLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLS-VAALA 133

Query: 125 VLPRLRSLTLHGNP 138
            LP LRSL L GNP
Sbjct: 134 ALPALRSLRLDGNP 147


>gi|239747236 PREDICTED: leucine rich repeat containing 38 [Homo
           sapiens]
          Length = 408

 Score = 36.6 bits (83), Expect = 0.009
 Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 66  DFNQVASQLLEHPENLAWIDLSFNDLTSI-DPVLTTFFNLSVLYLHGNSIQRLGEVNKLA 124
           +  Q+ +        L  + L+ N+L  + +    T  +L VL L+ N+++ L  V  LA
Sbjct: 229 NLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLS-VAALA 287

Query: 125 VLPRLRSLTLHGNP 138
            LP LRSL L GNP
Sbjct: 288 ALPALRSLRLDGNP 301


>gi|239741057 PREDICTED: leucine rich repeat containing 38 [Homo
           sapiens]
          Length = 408

 Score = 36.6 bits (83), Expect = 0.009
 Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 66  DFNQVASQLLEHPENLAWIDLSFNDLTSI-DPVLTTFFNLSVLYLHGNSIQRLGEVNKLA 124
           +  Q+ +        L  + L+ N+L  + +    T  +L VL L+ N+++ L  V  LA
Sbjct: 229 NLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLS-VAALA 287

Query: 125 VLPRLRSLTLHGNP 138
            LP LRSL L GNP
Sbjct: 288 ALPALRSLRLDGNP 301


>gi|46397373 leucine rich repeat containing 20 isoform 2 [Homo
           sapiens]
          Length = 134

 Score = 36.6 bits (83), Expect = 0.009
 Identities = 35/104 (33%), Positives = 48/104 (46%), Gaps = 8/104 (7%)

Query: 39  RPLKRSKSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVL 98
           R +  +    S T  L L  N L+ L   ++V++  L+H   L  IDLS N        L
Sbjct: 14  RKVNETVESGSDTLELHLEGNFLHRLP--SEVSA--LQH---LKAIDLSRNQFQDFPEQL 66

Query: 99  TTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEE 142
           T    L  + L  N I  +  V KLA +P LRS+ L  NP+  E
Sbjct: 67  TALPALETINLEENEIVDV-PVEKLAAMPALRSINLRFNPLNAE 109


>gi|46397369 leucine rich repeat containing 20 isoform 1 [Homo
           sapiens]
          Length = 184

 Score = 36.2 bits (82), Expect = 0.012
 Identities = 24/64 (37%), Positives = 31/64 (48%), Gaps = 1/64 (1%)

Query: 79  ENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNP 138
           ++L  IDLS N        LT    L  + L  N I  +  V KLA +P LRS+ L  NP
Sbjct: 97  QHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIVDV-PVEKLAAMPALRSINLRFNP 155

Query: 139 MEEE 142
           +  E
Sbjct: 156 LNAE 159



 Score = 30.0 bits (66), Expect = 0.86
 Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 3/59 (5%)

Query: 84  IDLSFNDLTSI-DPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEE 141
           I L+ N+L S+    +TTF  L  L+L GN + RL   ++++ L  L+++ L  N  ++
Sbjct: 55  ITLANNELKSLTSKFMTTFSQLRELHLEGNFLHRL--PSEVSALQHLKAIDLSRNQFQD 111


>gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo
           sapiens]
          Length = 754

 Score = 35.8 bits (81), Expect = 0.016
 Identities = 26/70 (37%), Positives = 41/70 (58%), Gaps = 2/70 (2%)

Query: 79  ENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNP 138
           +NL  +DLS N +TS+  +     +L  L L+ N+I  L EV++L  LP L+ L L  NP
Sbjct: 50  KNLRSLDLSRNLITSLKGI-QYLCSLQDLNLYYNNIPSLVEVSRLQPLPFLKELDLRLNP 108

Query: 139 -MEEEKGYRV 147
            + ++  YR+
Sbjct: 109 VVRKDTDYRL 118


>gi|239752518 PREDICTED: similar to leucine rich repeat containing
           50, partial [Homo sapiens]
          Length = 489

 Score = 35.8 bits (81), Expect = 0.016
 Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 57  NNNVLNDLRDFNQVASQLLEHPENLAWID------LSFNDLTSIDPVLTTFFNLSVLYLH 110
           N N L +LR  N +A   L H +NL  +D      L  N +T +  V      L  L+L 
Sbjct: 20  NINHLCELRVLN-LARNFLSHVDNLNGLDSLTELNLRHNQITFVRDV-DNLPCLQHLFLS 77

Query: 111 GNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYR 146
            N+I     V+ LA    L  +T  GNP+ +E  Y+
Sbjct: 78  FNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYK 113


>gi|37221175 PH domain and leucine rich repeat protein phosphatase
           [Homo sapiens]
          Length = 1205

 Score = 35.8 bits (81), Expect = 0.016
 Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 21/122 (17%)

Query: 38  LRPLKRSKSGKSLTQSLWLNNNVLND-----------LRDFNQVASQLLEHP-------E 79
           L P   S+   S+ Q L+L NN L D           L+  +   ++L   P       E
Sbjct: 489 LPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLE 548

Query: 80  NLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPM 139
            L  IDLS N L +I   +     +  +  H N I+   EV +   LP ++ + L  N +
Sbjct: 549 ELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPEVMQ---LPEIKCVDLSCNEL 605

Query: 140 EE 141
            E
Sbjct: 606 SE 607



 Score = 34.7 bits (78), Expect = 0.035
 Identities = 25/92 (27%), Positives = 48/92 (52%), Gaps = 3/92 (3%)

Query: 48  KSLTQSLWLNNNVLNDLRDFNQVAS--QLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLS 105
           +S+  ++ + +N+   L D N + S    LE+ + L+++ LSFN+ T I  VL     + 
Sbjct: 215 RSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVD 274

Query: 106 VLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGN 137
            L + GN ++ L  +  L  +P ++ + L  N
Sbjct: 275 KLCMSGNCVETL-RLQALRKMPHIKHVDLRLN 305


>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
          Length = 686

 Score = 35.8 bits (81), Expect = 0.016
 Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 57  NNNVLNDLRDFNQVASQLLEHPENLAWID------LSFNDLTSIDPVLTTFFNLSVLYLH 110
           N N L +LR  N +A   L H +NL  +D      L  N +T +  V      L  L+L 
Sbjct: 195 NINHLCELRVLN-LARNFLSHVDNLNGLDSLTELNLRHNQITFVRDV-DNLPCLQHLFLS 252

Query: 111 GNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYR 146
            N+I     V+ LA    L  +T  GNP+ +E  Y+
Sbjct: 253 FNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYK 288


>gi|15529980 leucine rich repeat containing 46 [Homo sapiens]
          Length = 321

 Score = 35.8 bits (81), Expect = 0.016
 Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 6/97 (6%)

Query: 45  KSGKSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNL 104
           + G  +T++L    N+     +  +++ ++    + L  + L    +T+I   L    NL
Sbjct: 12  EGGVCITEALITKRNLT--FPEDGELSEKMFHTLDELQTVRLDREGITTIRN-LEGLQNL 68

Query: 105 SVLYLHGNSIQRLGEVNKLAVLPRLRSLTLHGNPMEE 141
             LYL GN IQ   ++  LA +P LR L+L GN + +
Sbjct: 69  HSLYLQGNKIQ---QIENLACIPSLRFLSLAGNQIRQ 102


>gi|148664188 leucine rich repeat containing 43 isoform 2 [Homo
           sapiens]
          Length = 471

 Score = 35.0 bits (79), Expect = 0.027
 Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 16/81 (19%)

Query: 57  NNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLT---TFFNLSVLYLHGNS 113
           +N +L  L      A+    H  NL  +DL FNDLT +  ++T   T  +L +L L G  
Sbjct: 19  HNKLLGPLESLYVTAN----HWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQG-- 72

Query: 114 IQRLGEVNKLAVLPRLRSLTL 134
                  N LA++P  R LT+
Sbjct: 73  -------NPLALVPYYRGLTI 86


>gi|148664213 leucine rich repeat containing 43 isoform 1 [Homo
           sapiens]
          Length = 656

 Score = 35.0 bits (79), Expect = 0.027
 Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 16/81 (19%)

Query: 57  NNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLT---TFFNLSVLYLHGNS 113
           +N +L  L      A+    H  NL  +DL FNDLT +  ++T   T  +L +L L G  
Sbjct: 204 HNKLLGPLESLYVTAN----HWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQG-- 257

Query: 114 IQRLGEVNKLAVLPRLRSLTL 134
                  N LA++P  R LT+
Sbjct: 258 -------NPLALVPYYRGLTI 271


>gi|63003903 leucine rich repeat containing 10 [Homo sapiens]
          Length = 277

 Score = 34.7 bits (78), Expect = 0.035
 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 9/84 (10%)

Query: 54  LWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNS 113
           L+L++N LN L          L   +NL  + L FN+  ++  V+ T   L +LYL  N 
Sbjct: 57  LYLSDNHLNSL-------PPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNK 109

Query: 114 IQRLGEVNKLAVLPRLRSLTLHGN 137
           +  L   ++L++L  LR+L +  N
Sbjct: 110 LCDL--PSELSLLQNLRTLWIEAN 131


>gi|218931217 leucine rich repeat containing 61 [Homo sapiens]
          Length = 259

 Score = 34.7 bits (78), Expect = 0.035
 Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 48  KSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVL 107
           KS T    L + +L  LR         L     L W+DLS N LT + P L +   L+VL
Sbjct: 22  KSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGP-LASLRQLAVL 80

Query: 108 YLHGNSIQRLGEVNKLAVLPRLRSLTLHGN 137
            +  N   RL  +  LA    L+SL   GN
Sbjct: 81  NVSNN---RLTGLEPLATCENLQSLNAAGN 107


>gi|13027616 leucine rich repeat containing 61 [Homo sapiens]
          Length = 259

 Score = 34.7 bits (78), Expect = 0.035
 Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 4/90 (4%)

Query: 48  KSLTQSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVL 107
           KS T    L + +L  LR         L     L W+DLS N LT + P L +   L+VL
Sbjct: 22  KSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGP-LASLRQLAVL 80

Query: 108 YLHGNSIQRLGEVNKLAVLPRLRSLTLHGN 137
            +  N   RL  +  LA    L+SL   GN
Sbjct: 81  NVSNN---RLTGLEPLATCENLQSLNAAGN 107


>gi|21361633 leucine rich repeat containing 40 [Homo sapiens]
          Length = 602

 Score = 34.7 bits (78), Expect = 0.035
 Identities = 22/48 (45%), Positives = 25/48 (52%), Gaps = 3/48 (6%)

Query: 68  NQVAS---QLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGN 112
           NQV S   Q ++  ENL  +DL  NDL  I P L    NL  L L GN
Sbjct: 528 NQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGN 575



 Score = 31.6 bits (70), Expect = 0.29
 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 69  QVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEVNKLAVLPR 128
           ++  +++E  E ++ +DLSFN L+ I   L     L+ L L  N +  L E  ++  L R
Sbjct: 439 EIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLPE--EMESLVR 496

Query: 129 LRSLTLHGN--PMEEEKGYRV 147
           L+++ L  N   M  E  YR+
Sbjct: 497 LQTINLSFNRFKMLPEVLYRI 517



 Score = 28.9 bits (63), Expect = 1.9
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 5/77 (6%)

Query: 63  DLRDFNQVAS--QLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHGNSIQRLGEV 120
           D+ D NQ+ S    +   ENL  +++S N L  +   +T   NL  LYL  N +  + E 
Sbjct: 111 DIHD-NQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISE- 168

Query: 121 NKLAVLPRLRSLTLHGN 137
                L  L  L L  N
Sbjct: 169 -GFEQLSNLEDLDLSNN 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,198,149
Number of Sequences: 37866
Number of extensions: 239733
Number of successful extensions: 1388
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 1246
Number of HSP's gapped (non-prelim): 226
length of query: 158
length of database: 18,247,518
effective HSP length: 94
effective length of query: 64
effective length of database: 14,688,114
effective search space: 940039296
effective search space used: 940039296
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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