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Search of human proteins with 223555951
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223555951 nuclear receptor subfamily 2, group F, member 2
isoform c [Homo sapiens]
(261 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223555953 nuclear receptor subfamily 2, group F, member 2 iso... 524 e-149
gi|223555951 nuclear receptor subfamily 2, group F, member 2 iso... 524 e-149
gi|223555949 nuclear receptor subfamily 2, group F, member 2 iso... 524 e-149
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 524 e-149
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 503 e-143
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 345 2e-95
gi|7657395 photoreceptor-specific nuclear receptor isoform b [Ho... 177 8e-45
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 169 2e-42
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 166 2e-41
gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo... 159 2e-39
gi|11415052 retinoid X receptor, beta [Homo sapiens] 158 5e-39
gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Hom... 146 2e-35
gi|7706515 photoreceptor-specific nuclear receptor isoform a [Ho... 134 8e-32
gi|189491739 nuclear receptor subfamily 2, group C, member 1 iso... 131 5e-31
gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo sa... 125 5e-29
gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo sa... 125 5e-29
gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo sa... 125 5e-29
gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo sa... 125 5e-29
gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens] 125 5e-29
gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo sa... 122 4e-28
gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo sa... 122 4e-28
gi|238550159 estrogen-related receptor beta [Homo sapiens] 117 8e-27
gi|45545405 nuclear receptor subfamily 5, group A, member 2 isof... 117 1e-26
gi|4504343 nuclear receptor subfamily 5, group A, member 2 isofo... 117 1e-26
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 114 7e-26
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 114 7e-26
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 114 7e-26
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 114 7e-26
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 102 4e-22
gi|13259503 short heterodimer partner [Homo sapiens] 95 5e-20
>gi|223555953 nuclear receptor subfamily 2, group F, member 2
isoform c [Homo sapiens]
Length = 261
Score = 524 bits (1350), Expect = e-149
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 60
MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC
Sbjct: 1 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 60
Query: 61 ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 120
ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA
Sbjct: 61 ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 120
Query: 121 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 180
GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH
Sbjct: 121 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 180
Query: 181 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 240
VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE
Sbjct: 181 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 240
Query: 241 TLIRDMLLSGSSFNWPYMAIQ 261
TLIRDMLLSGSSFNWPYMAIQ
Sbjct: 241 TLIRDMLLSGSSFNWPYMAIQ 261
>gi|223555951 nuclear receptor subfamily 2, group F, member 2
isoform c [Homo sapiens]
Length = 261
Score = 524 bits (1350), Expect = e-149
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 60
MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC
Sbjct: 1 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 60
Query: 61 ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 120
ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA
Sbjct: 61 ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 120
Query: 121 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 180
GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH
Sbjct: 121 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 180
Query: 181 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 240
VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE
Sbjct: 181 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 240
Query: 241 TLIRDMLLSGSSFNWPYMAIQ 261
TLIRDMLLSGSSFNWPYMAIQ
Sbjct: 241 TLIRDMLLSGSSFNWPYMAIQ 261
>gi|223555949 nuclear receptor subfamily 2, group F, member 2
isoform b [Homo sapiens]
Length = 281
Score = 524 bits (1350), Expect = e-149
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 60
MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC
Sbjct: 21 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 80
Query: 61 ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 120
ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA
Sbjct: 81 ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 140
Query: 121 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 180
GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH
Sbjct: 141 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 200
Query: 181 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 240
VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE
Sbjct: 201 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 260
Query: 241 TLIRDMLLSGSSFNWPYMAIQ 261
TLIRDMLLSGSSFNWPYMAIQ
Sbjct: 261 TLIRDMLLSGSSFNWPYMAIQ 281
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 524 bits (1350), Expect = e-149
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 60
MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC
Sbjct: 154 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 213
Query: 61 ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 120
ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA
Sbjct: 214 ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 273
Query: 121 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 180
GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH
Sbjct: 274 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 333
Query: 181 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 240
VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE
Sbjct: 334 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 393
Query: 241 TLIRDMLLSGSSFNWPYMAIQ 261
TLIRDMLLSGSSFNWPYMAIQ
Sbjct: 394 TLIRDMLLSGSSFNWPYMAIQ 414
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 503 bits (1294), Expect = e-143
Identities = 249/261 (95%), Positives = 256/261 (98%)
Query: 1 MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 60
MPPTQP GQ+ALTNGDPLN H YLSGYISLLLRAEPYPTSR+GSQCMQPNNIMGIENIC
Sbjct: 161 MPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENIC 220
Query: 61 ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 120
ELAAR+LFSAVEWARNIPFFPDLQITDQV+LLRLTWSELFVLNAAQCSMPLHVAPLLAAA
Sbjct: 221 ELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAA 280
Query: 121 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 180
GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSD AH
Sbjct: 281 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAH 340
Query: 181 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 240
+ESLQEKSQCALEEYVRSQYPNQP+RFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE
Sbjct: 341 IESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 400
Query: 241 TLIRDMLLSGSSFNWPYMAIQ 261
TLIRDMLLSGSSFNWPYM+IQ
Sbjct: 401 TLIRDMLLSGSSFNWPYMSIQ 421
>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
sapiens]
Length = 404
Score = 345 bits (886), Expect = 2e-95
Identities = 174/248 (70%), Positives = 205/248 (82%), Gaps = 2/248 (0%)
Query: 12 ALTNGDPLNCHSYLSGYISLLLRAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFS 69
A+ +G L +S I+ LLRAEPYP + RFG+ ++GI+N+CELAAR+LFS
Sbjct: 153 AVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFS 212
Query: 70 AVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSA 129
VEWAR+ PFFP+L + DQVALLRL+WSELFVLNAAQ ++PLH APLLAAAGLHA+PM+A
Sbjct: 213 TVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAA 272
Query: 130 DRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQ 189
+R VAFMD +R FQEQV+KL L VDSAEY CLKAI LFT DACGLSD AHVESLQEK+Q
Sbjct: 273 ERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQ 332
Query: 190 CALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLS 249
AL EYVR+QYP+QP RFG+LLLRLP+LR V +S+I QLFF+RLVGKTPIETLIRDMLLS
Sbjct: 333 VALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLS 392
Query: 250 GSSFNWPY 257
GS+FNWPY
Sbjct: 393 GSTFNWPY 400
>gi|7657395 photoreceptor-specific nuclear receptor isoform b [Homo
sapiens]
Length = 410
Score = 177 bits (449), Expect = 8e-45
Identities = 92/209 (44%), Positives = 135/209 (64%), Gaps = 5/209 (2%)
Query: 38 YPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWS 97
+P+S + S ++ G+++I E +AR+LF AV+WA+N+P F L DQV LL WS
Sbjct: 204 FPSSPYSS-----SSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWS 258
Query: 98 ELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSA 157
ELF+L A Q S+PL PLLA A+ + R+ R+ QE + + +AL VD
Sbjct: 259 ELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPT 318
Query: 158 EYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSL 217
E++C+KA+VLF + GL D HVE+LQ++SQ L ++ ++ +P+QP RFGKLLL LPSL
Sbjct: 319 EFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSL 378
Query: 218 RTVSSSVIEQLFFVRLVGKTPIETLIRDM 246
R +++ IE LFF + +G TP+E L+ DM
Sbjct: 379 RFITAERIELLFFRKTIGNTPMEKLLCDM 407
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 169 bits (429), Expect = 2e-42
Identities = 93/215 (43%), Positives = 128/215 (59%), Gaps = 2/215 (0%)
Query: 33 LRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALL 92
L EP T +G M+ + + NIC A + LF+ VEWA+ IP F DL + DQV LL
Sbjct: 244 LAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILL 302
Query: 93 RLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKAL 152
R W+EL + + + S+ + LLA GLH SA R+ E V K+K +
Sbjct: 303 RAGWNELLIASFSHRSVSVQDGILLAT-GLHVHRSSAHSAGVGSIFDRVLTELVSKMKDM 361
Query: 153 HVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLL 212
+D +E CL+AIVLF DA GLS+ + VE+L+EK LE Y + +YP QP RF KLLL
Sbjct: 362 QMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLL 421
Query: 213 RLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 247
RLP+LR++ +E LFF +L+G TPI+T + +ML
Sbjct: 422 RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 456
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 166 bits (420), Expect = 2e-41
Identities = 90/214 (42%), Positives = 128/214 (59%), Gaps = 3/214 (1%)
Query: 34 RAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLR 93
+ E Y + G PN+ + NIC+ A + LF+ VEWA+ IP F +L + DQV LLR
Sbjct: 245 KTETYVEANMGLNPSSPND--PVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLR 302
Query: 94 LTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALH 153
W+EL + + + S+ + LLA GLH SA R+ E V K++ +
Sbjct: 303 AGWNELLIASFSHRSIAVKDGILLAT-GLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQ 361
Query: 154 VDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLR 213
+D E CL+AIVLF D+ GLS+ A VE+L+EK +LE Y + +YP QP RF KLLLR
Sbjct: 362 MDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLR 421
Query: 214 LPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 247
LP+LR++ +E LFF +L+G TPI+T + +ML
Sbjct: 422 LPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455
>gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo
sapiens]
Length = 385
Score = 159 bits (403), Expect = 2e-39
Identities = 78/200 (39%), Positives = 124/200 (62%), Gaps = 7/200 (3%)
Query: 57 ENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPL 116
E++CE AAR+LF +++WA+++P F L + DQ+ LL W ELFVL AQ ++P+ L
Sbjct: 183 ESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTL 242
Query: 117 LAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFT------- 169
LA +G++ + ++ + I+ QE V + + L +D+ E++CLK IV F
Sbjct: 243 LAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSG 302
Query: 170 SDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLF 229
S+ + A + +LQ+++Q L Y+ ++YP QP RFGKLLL LP+LR++S S IE++F
Sbjct: 303 SELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVF 362
Query: 230 FVRLVGKTPIETLIRDMLLS 249
F + +G PI L+ DM S
Sbjct: 363 FKKTIGNVPITRLLSDMYKS 382
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 158 bits (399), Expect = 5e-39
Identities = 86/204 (42%), Positives = 121/204 (59%), Gaps = 3/204 (1%)
Query: 44 GSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLN 103
G PN+ + NIC+ A + LF+ VEWA+ IP F L + DQV LLR W+EL + +
Sbjct: 326 GGSGSSPND--PVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIAS 383
Query: 104 AAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLK 163
+ S+ + LLA GLH SA R+ E V K++ + +D E CL+
Sbjct: 384 FSHRSIDVRDGILLAT-GLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLR 442
Query: 164 AIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSS 223
AI+LF DA GLS+ + VE L+EK +LE Y + +YP Q RF KLLLRLP+LR++
Sbjct: 443 AIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLK 502
Query: 224 VIEQLFFVRLVGKTPIETLIRDML 247
+E LFF +L+G TPI+T + +ML
Sbjct: 503 CLEHLFFFKLIGDTPIDTFLMEML 526
>gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Homo
sapiens]
Length = 615
Score = 146 bits (369), Expect = 2e-35
Identities = 76/196 (38%), Positives = 117/196 (59%), Gaps = 6/196 (3%)
Query: 54 MGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHV 113
+ + ICE A+R+LF ++ WAR+IP F L +L+R W+ELF L AQC+ + +
Sbjct: 400 LNVHYICESASRLLFLSMHWARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSL 459
Query: 114 APLLAAAGLHAS------PMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVL 167
+ +LAA H +S DR+ M+HI QE + L +D EY+ LKAIVL
Sbjct: 460 STILAAIVNHLQNSIQEDKLSGDRIKQVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVL 519
Query: 168 FTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQ 227
F+ D GL+ + +E QEK+Q L++YV+ Y R ++L+RLP+LR +SS++ E+
Sbjct: 520 FSPDHPGLTSTSQIEKFQEKAQMELQDYVQKTYSEDTYRLARILVRLPALRLMSSNITEE 579
Query: 228 LFFVRLVGKTPIETLI 243
LFF L+G I+++I
Sbjct: 580 LFFTGLIGNVSIDSII 595
>gi|7706515 photoreceptor-specific nuclear receptor isoform a [Homo
sapiens]
Length = 367
Score = 134 bits (337), Expect = 8e-32
Identities = 69/169 (40%), Positives = 105/169 (62%), Gaps = 5/169 (2%)
Query: 38 YPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWS 97
+P+S + S ++ G+++I E +AR+LF AV+WA+N+P F L DQV LL WS
Sbjct: 204 FPSSPYSS-----SSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWS 258
Query: 98 ELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSA 157
ELF+L A Q S+PL PLLA A+ + R+ R+ QE + + +AL VD
Sbjct: 259 ELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPT 318
Query: 158 EYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTR 206
E++C+KA+VLF + GL D HVE+LQ++SQ L ++ ++ +P+QP R
Sbjct: 319 EFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVR 367
>gi|189491739 nuclear receptor subfamily 2, group C, member 1
isoform a [Homo sapiens]
Length = 603
Score = 131 bits (330), Expect = 5e-31
Identities = 72/200 (36%), Positives = 115/200 (57%), Gaps = 6/200 (3%)
Query: 54 MGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHV 113
+ + I E A+R+LF ++ WA +IP F L + ++L++ W+ELF L AQC ++V
Sbjct: 388 LNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNV 447
Query: 114 APLLAAA------GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVL 167
A +LA L MS +R M+HI QE + L +D EY+ LKAIVL
Sbjct: 448 ATILATFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVL 507
Query: 168 FTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQ 227
F+ D L ++ +E QEK+ ++Y+ YP+ R +LLLRLP+LR +++++ E+
Sbjct: 508 FSPDHPSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEE 567
Query: 228 LFFVRLVGKTPIETLIRDML 247
LFF L+G I+++I +L
Sbjct: 568 LFFKGLIGNIRIDSVIPHIL 587
>gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo
sapiens]
Length = 464
Score = 125 bits (313), Expect = 5e-29
Identities = 77/213 (36%), Positives = 119/213 (55%), Gaps = 7/213 (3%)
Query: 48 MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 107
++ I I ++CE L VEWA+ IP F +L + DQVALLR E +L A +
Sbjct: 176 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 235
Query: 108 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 164
SM LL + H ++ V+ IRI E V + L +D EY+ LKA
Sbjct: 236 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 291
Query: 165 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 224
I+ F DA GLSD ++ L+ + Q +LE+Y+ + + RFG+LLL LP+L++++ +
Sbjct: 292 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 351
Query: 225 IEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 257
IEQ+ F++L G I+ L+++MLL GS + P+
Sbjct: 352 IEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 384
>gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo
sapiens]
Length = 474
Score = 125 bits (313), Expect = 5e-29
Identities = 77/213 (36%), Positives = 119/213 (55%), Gaps = 7/213 (3%)
Query: 48 MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 107
++ I I ++CE L VEWA+ IP F +L + DQVALLR E +L A +
Sbjct: 176 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 235
Query: 108 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 164
SM LL + H ++ V+ IRI E V + L +D EY+ LKA
Sbjct: 236 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 291
Query: 165 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 224
I+ F DA GLSD ++ L+ + Q +LE+Y+ + + RFG+LLL LP+L++++ +
Sbjct: 292 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 351
Query: 225 IEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 257
IEQ+ F++L G I+ L+++MLL GS + P+
Sbjct: 352 IEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 384
>gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo
sapiens]
Length = 442
Score = 125 bits (313), Expect = 5e-29
Identities = 77/213 (36%), Positives = 119/213 (55%), Gaps = 7/213 (3%)
Query: 48 MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 107
++ I I ++CE L VEWA+ IP F +L + DQVALLR E +L A +
Sbjct: 154 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 213
Query: 108 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 164
SM LL + H ++ V+ IRI E V + L +D EY+ LKA
Sbjct: 214 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 269
Query: 165 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 224
I+ F DA GLSD ++ L+ + Q +LE+Y+ + + RFG+LLL LP+L++++ +
Sbjct: 270 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 329
Query: 225 IEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 257
IEQ+ F++L G I+ L+++MLL GS + P+
Sbjct: 330 IEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 362
>gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo
sapiens]
Length = 452
Score = 125 bits (313), Expect = 5e-29
Identities = 77/213 (36%), Positives = 119/213 (55%), Gaps = 7/213 (3%)
Query: 48 MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 107
++ I I ++CE L VEWA+ IP F +L + DQVALLR E +L A +
Sbjct: 154 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 213
Query: 108 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 164
SM LL + H ++ V+ IRI E V + L +D EY+ LKA
Sbjct: 214 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 269
Query: 165 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 224
I+ F DA GLSD ++ L+ + Q +LE+Y+ + + RFG+LLL LP+L++++ +
Sbjct: 270 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 329
Query: 225 IEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 257
IEQ+ F++L G I+ L+++MLL GS + P+
Sbjct: 330 IEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 362
>gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]
Length = 445
Score = 125 bits (313), Expect = 5e-29
Identities = 74/200 (37%), Positives = 118/200 (59%), Gaps = 2/200 (1%)
Query: 53 IMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLH 112
I I ++CE + L VEWA+ IP F +L + DQVALLR E +L A + SM ++
Sbjct: 170 IASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSM-MY 228
Query: 113 VAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDA 172
LL S + ++ + + R+ E V + + +D EY+CLKAIV F DA
Sbjct: 229 KDILLLGNNYVIHRNSCEVEISRVAN-RVLDELVRPFQEIQIDDNEYACLKAIVFFDPDA 287
Query: 173 CGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVR 232
GLSD +++++ + Q LE+Y+ + + RFG+LLL LP+L++++ +IEQ+ FV+
Sbjct: 288 KGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVK 347
Query: 233 LVGKTPIETLIRDMLLSGSS 252
L G I+ L+++MLL G+S
Sbjct: 348 LFGMVKIDNLLQEMLLGGAS 367
>gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo
sapiens]
Length = 417
Score = 122 bits (305), Expect = 4e-28
Identities = 75/206 (36%), Positives = 115/206 (55%), Gaps = 7/206 (3%)
Query: 48 MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 107
++ I I ++CE L VEWA+ IP F +L + DQVALLR E +L A +
Sbjct: 176 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 235
Query: 108 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 164
SM LL + H ++ V+ IRI E V + L +D EY+ LKA
Sbjct: 236 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 291
Query: 165 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 224
I+ F DA GLSD ++ L+ + Q +LE+Y+ + + RFG+LLL LP+L++++ +
Sbjct: 292 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 351
Query: 225 IEQLFFVRLVGKTPIETLIRDMLLSG 250
IEQ+ F++L G I+ L+++MLL G
Sbjct: 352 IEQIQFIKLFGMAKIDNLLQEMLLGG 377
>gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo
sapiens]
Length = 395
Score = 122 bits (305), Expect = 4e-28
Identities = 75/206 (36%), Positives = 115/206 (55%), Gaps = 7/206 (3%)
Query: 48 MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 107
++ I I ++CE L VEWA+ IP F +L + DQVALLR E +L A +
Sbjct: 154 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 213
Query: 108 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 164
SM LL + H ++ V+ IRI E V + L +D EY+ LKA
Sbjct: 214 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 269
Query: 165 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 224
I+ F DA GLSD ++ L+ + Q +LE+Y+ + + RFG+LLL LP+L++++ +
Sbjct: 270 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 329
Query: 225 IEQLFFVRLVGKTPIETLIRDMLLSG 250
IEQ+ F++L G I+ L+++MLL G
Sbjct: 330 IEQIQFIKLFGMAKIDNLLQEMLLGG 355
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 117 bits (294), Expect = 8e-27
Identities = 72/223 (32%), Positives = 113/223 (50%), Gaps = 2/223 (0%)
Query: 25 LSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQ 84
L+ +S LL AEP M +I + +C+LA R L + WA++IP F L
Sbjct: 209 LTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLS 268
Query: 85 ITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQE 144
+ DQ++LL+ W E+ +L S+P L A + R+ ++ R +
Sbjct: 269 LGDQMSLLQSAWMEILILGIVYRSLPYD--DKLVYAEDYIMDEEHSRLAGLLELYRAILQ 326
Query: 145 QVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQP 204
V + K L V+ E+ LKA+ L SD+ + D+ V+ LQ+ AL++Y SQ +P
Sbjct: 327 LVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEP 386
Query: 205 TRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 247
R GKLLL LP LR ++ ++ + V+L GK P+ L +ML
Sbjct: 387 WRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEML 429
>gi|45545405 nuclear receptor subfamily 5, group A, member 2 isoform
1 [Homo sapiens]
Length = 541
Score = 117 bits (292), Expect = 1e-26
Identities = 69/193 (35%), Positives = 107/193 (55%), Gaps = 5/193 (2%)
Query: 59 ICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAP--- 115
+C++A + LFS VEWAR+ FF +L++ DQ+ LL+ WSEL +L+ + +H
Sbjct: 345 MCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQV-VHGKEGSI 403
Query: 116 -LLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACG 174
L+ + S +++ + + QE V KL++L D E+ CLK +VLF+ D
Sbjct: 404 FLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKN 463
Query: 175 LSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLV 234
L + VE +QE+ AL +Y YP Q +FG+LLLRLP +R +S E L++ L
Sbjct: 464 LENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLN 523
Query: 235 GKTPIETLIRDML 247
G P L+ +ML
Sbjct: 524 GDVPYNNLLIEML 536
>gi|4504343 nuclear receptor subfamily 5, group A, member 2 isoform
2 [Homo sapiens]
Length = 495
Score = 117 bits (292), Expect = 1e-26
Identities = 69/193 (35%), Positives = 107/193 (55%), Gaps = 5/193 (2%)
Query: 59 ICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAP--- 115
+C++A + LFS VEWAR+ FF +L++ DQ+ LL+ WSEL +L+ + +H
Sbjct: 299 MCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQV-VHGKEGSI 357
Query: 116 -LLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACG 174
L+ + S +++ + + QE V KL++L D E+ CLK +VLF+ D
Sbjct: 358 FLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKN 417
Query: 175 LSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLV 234
L + VE +QE+ AL +Y YP Q +FG+LLLRLP +R +S E L++ L
Sbjct: 418 LENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLN 477
Query: 235 GKTPIETLIRDML 247
G P L+ +ML
Sbjct: 478 GDVPYNNLLIEML 490
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 114 bits (286), Expect = 7e-26
Identities = 66/219 (30%), Positives = 111/219 (50%), Gaps = 2/219 (0%)
Query: 29 ISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQ 88
+S LL AEP + ++I + +C+LA R L + WA++IP F L + DQ
Sbjct: 215 VSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQ 274
Query: 89 VALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEK 148
++LL+ W E+ +L S+ L A + ++ +D + V+K
Sbjct: 275 MSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKK 332
Query: 149 LKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFG 208
K++ ++ E+ LKAI L SD+ + DV V+ LQ+ AL++Y Q+ P R G
Sbjct: 333 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 392
Query: 209 KLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 247
K+L+ LP LR S+ ++ + ++L GK P+ L +ML
Sbjct: 393 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 114 bits (286), Expect = 7e-26
Identities = 66/219 (30%), Positives = 111/219 (50%), Gaps = 2/219 (0%)
Query: 29 ISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQ 88
+S LL AEP + ++I + +C+LA R L + WA++IP F L + DQ
Sbjct: 215 VSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQ 274
Query: 89 VALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEK 148
++LL+ W E+ +L S+ L A + ++ +D + V+K
Sbjct: 275 MSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKK 332
Query: 149 LKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFG 208
K++ ++ E+ LKAI L SD+ + DV V+ LQ+ AL++Y Q+ P R G
Sbjct: 333 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 392
Query: 209 KLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 247
K+L+ LP LR S+ ++ + ++L GK P+ L +ML
Sbjct: 393 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 114 bits (286), Expect = 7e-26
Identities = 66/219 (30%), Positives = 111/219 (50%), Gaps = 2/219 (0%)
Query: 29 ISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQ 88
+S LL AEP + ++I + +C+LA R L + WA++IP F L + DQ
Sbjct: 238 VSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQ 297
Query: 89 VALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEK 148
++LL+ W E+ +L S+ L A + ++ +D + V+K
Sbjct: 298 MSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKK 355
Query: 149 LKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFG 208
K++ ++ E+ LKAI L SD+ + DV V+ LQ+ AL++Y Q+ P R G
Sbjct: 356 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 415
Query: 209 KLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 247
K+L+ LP LR S+ ++ + ++L GK P+ L +ML
Sbjct: 416 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 454
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 114 bits (286), Expect = 7e-26
Identities = 66/219 (30%), Positives = 111/219 (50%), Gaps = 2/219 (0%)
Query: 29 ISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQ 88
+S LL AEP + ++I + +C+LA R L + WA++IP F L + DQ
Sbjct: 215 VSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQ 274
Query: 89 VALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEK 148
++LL+ W E+ +L S+ L A + ++ +D + V+K
Sbjct: 275 MSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKK 332
Query: 149 LKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFG 208
K++ ++ E+ LKAI L SD+ + DV V+ LQ+ AL++Y Q+ P R G
Sbjct: 333 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 392
Query: 209 KLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 247
K+L+ LP LR S+ ++ + ++L GK P+ L +ML
Sbjct: 393 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 102 bits (253), Expect = 4e-22
Identities = 71/236 (30%), Positives = 111/236 (47%), Gaps = 6/236 (2%)
Query: 16 GDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWAR 75
G P + ++ +S LL EP ++ + +C+L R + + WA+
Sbjct: 185 GGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAK 244
Query: 76 NIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAF 135
+IP F L ++DQ+++L+ W E+ VL AQ S+PL LA A R
Sbjct: 245 SIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQ--DELAFAEDLVLDEEGARAAGL 302
Query: 136 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEY 195
+ + V +L+AL ++ EY LKA+ L SD+ + D VE L+E AL EY
Sbjct: 303 GELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEY 362
Query: 196 VRSQY----PNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 247
+ + R G+LLL LP LR + V+ + V+L GK P+ L +ML
Sbjct: 363 EAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEML 418
>gi|13259503 short heterodimer partner [Homo sapiens]
Length = 257
Score = 95.1 bits (235), Expect = 5e-20
Identities = 70/235 (29%), Positives = 110/235 (46%), Gaps = 11/235 (4%)
Query: 25 LSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQ 84
L +S L+A P P SR + +P + C A +L V + RN+P F L
Sbjct: 21 LYALLSSSLKAVPRPRSRCLCRQHRPVQLCAPHRTCREALDVLAKTVAFLRNLPSFWQLP 80
Query: 85 ITDQVALLRLTWSELFVLNAAQCSMPLHVA----PLLAAAGLHASPMSA-------DRVV 133
DQ LL+ W LF+L AQ ++ VA P + L P S+ DR
Sbjct: 81 PQDQRRLLQGCWGPLFLLGLAQDAVTFEVAEAPVPSILKKILLEEPSSSGGSGQLPDRPQ 140
Query: 134 AFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALE 193
+ ++ Q +E +L + EY+CLK +LF D GL +H+ LQ+++ L
Sbjct: 141 PSLAAVQWLQCCLESFWSLELSPKEYACLKGTILFNPDVPGLQAASHIGHLQQEAHWVLC 200
Query: 194 EYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLL 248
E + P R ++LL +L+++ +S++ LFF ++G I L+ DMLL
Sbjct: 201 EVLEPWCPAAQGRLTRVLLTASTLKSIPTSLLGDLFFRPIIGDVDIAGLLGDMLL 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,695,751
Number of Sequences: 37866
Number of extensions: 392434
Number of successful extensions: 1249
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1050
Number of HSP's gapped (non-prelim): 132
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.