Search of human proteins with 223555949

Search of human proteins with 223555949

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223555949 nuclear receptor subfamily 2, group F, member 2
isoform b [Homo sapiens]
         (281 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223555949 nuclear receptor subfamily 2, group F, member 2 iso...   566   e-162
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof...   536   e-152
gi|223555953 nuclear receptor subfamily 2, group F, member 2 iso...   524   e-149
gi|223555951 nuclear receptor subfamily 2, group F, member 2 iso...   524   e-149
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo...   514   e-146
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom...   352   3e-97
gi|7657395 photoreceptor-specific nuclear receptor isoform b [Ho...   177   9e-45
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]        169   2e-42
gi|4506755 retinoid X receptor, alpha [Homo sapiens]                  166   2e-41
gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo...   159   2e-39
gi|11415052 retinoid X receptor, beta [Homo sapiens]                  158   6e-39
gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Hom...   146   2e-35
gi|7706515 photoreceptor-specific nuclear receptor isoform a [Ho...   134   9e-32
gi|189491739 nuclear receptor subfamily 2, group C, member 1 iso...   131   6e-31
gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo sa...   125   5e-29
gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo sa...   125   5e-29
gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo sa...   125   5e-29
gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo sa...   125   5e-29
gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]        125   5e-29
gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo sa...   122   5e-28
gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo sa...   122   5e-28
gi|238550159 estrogen-related receptor beta [Homo sapiens]            117   9e-27
gi|45545405 nuclear receptor subfamily 5, group A, member 2 isof...   117   1e-26
gi|4504343 nuclear receptor subfamily 5, group A, member 2 isofo...   117   1e-26
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi...   114   7e-26
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi...   114   7e-26
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi...   114   7e-26
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap...   114   7e-26
gi|18860920 estrogen-related receptor alpha [Homo sapiens]            102   5e-22
gi|13259503 short heterodimer partner [Homo sapiens]                   95   6e-20

>gi|223555949 nuclear receptor subfamily 2, group F, member 2
           isoform b [Homo sapiens]
          Length = 281

 Score =  566 bits (1458), Expect = e-162
 Identities = 281/281 (100%), Positives = 281/281 (100%)

Query: 1   MQAVWDLEQGKYGFAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPT 60
           MQAVWDLEQGKYGFAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPT
Sbjct: 1   MQAVWDLEQGKYGFAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPT 60

Query: 61  SRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELF 120
           SRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELF
Sbjct: 61  SRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELF 120

Query: 121 VLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYS 180
           VLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYS
Sbjct: 121 VLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYS 180

Query: 181 CLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTV 240
           CLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTV
Sbjct: 181 CLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTV 240

Query: 241 SSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ 281
           SSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
Sbjct: 241 SSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ 281


>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
           a [Homo sapiens]
          Length = 414

 Score =  536 bits (1380), Expect = e-152
 Identities = 269/275 (97%), Positives = 270/275 (98%)

Query: 7   LEQGKYGFAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQ 66
           L+ G    AVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQ
Sbjct: 140 LKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQ 199

Query: 67  CMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQ 126
           CMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQ
Sbjct: 200 CMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQ 259

Query: 127 CSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIV 186
           CSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIV
Sbjct: 260 CSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIV 319

Query: 187 LFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIE 246
           LFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIE
Sbjct: 320 LFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIE 379

Query: 247 QLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ 281
           QLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
Sbjct: 380 QLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ 414


>gi|223555953 nuclear receptor subfamily 2, group F, member 2
           isoform c [Homo sapiens]
          Length = 261

 Score =  524 bits (1350), Expect = e-149
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 21  MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 80
           MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC
Sbjct: 1   MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 60

Query: 81  ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 140
           ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA
Sbjct: 61  ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 120

Query: 141 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 200
           GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH
Sbjct: 121 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 180

Query: 201 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 260
           VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE
Sbjct: 181 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 240

Query: 261 TLIRDMLLSGSSFNWPYMAIQ 281
           TLIRDMLLSGSSFNWPYMAIQ
Sbjct: 241 TLIRDMLLSGSSFNWPYMAIQ 261


>gi|223555951 nuclear receptor subfamily 2, group F, member 2
           isoform c [Homo sapiens]
          Length = 261

 Score =  524 bits (1350), Expect = e-149
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 21  MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 80
           MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC
Sbjct: 1   MPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENIC 60

Query: 81  ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 140
           ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA
Sbjct: 61  ELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAA 120

Query: 141 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 200
           GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH
Sbjct: 121 GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAH 180

Query: 201 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 260
           VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE
Sbjct: 181 VESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIE 240

Query: 261 TLIRDMLLSGSSFNWPYMAIQ 281
           TLIRDMLLSGSSFNWPYMAIQ
Sbjct: 241 TLIRDMLLSGSSFNWPYMAIQ 261


>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
           sapiens]
          Length = 423

 Score =  514 bits (1324), Expect = e-146
 Identities = 257/275 (93%), Positives = 265/275 (96%)

Query: 7   LEQGKYGFAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQ 66
           L+ G    AVQRGRMPPTQP  GQ+ALTNGDPLN H YLSGYISLLLRAEPYPTSR+GSQ
Sbjct: 147 LKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQ 206

Query: 67  CMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQ 126
           CMQPNNIMGIENICELAAR+LFSAVEWARNIPFFPDLQITDQV+LLRLTWSELFVLNAAQ
Sbjct: 207 CMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQ 266

Query: 127 CSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIV 186
           CSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIV
Sbjct: 267 CSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIV 326

Query: 187 LFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIE 246
           LFTSDACGLSD AH+ESLQEKSQCALEEYVRSQYPNQP+RFGKLLLRLPSLRTVSSSVIE
Sbjct: 327 LFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIE 386

Query: 247 QLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ 281
           QLFFVRLVGKTPIETLIRDMLLSGSSFNWPYM+IQ
Sbjct: 387 QLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQ 421


>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
           sapiens]
          Length = 404

 Score =  352 bits (902), Expect = 3e-97
 Identities = 184/278 (66%), Positives = 217/278 (78%), Gaps = 17/278 (6%)

Query: 15  AVQRGRMPPTQPTHGQFALTNGDP-------------LNCHSYLSGYISLLLRAEPYPTS 61
           AVQRGR+P + P  G  A ++G P             L     +S  I+ LLRAEPYP +
Sbjct: 125 AVQRGRIPHSLP--GAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAA 182

Query: 62  --RFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSEL 119
             RFG+       ++GI+N+CELAAR+LFS VEWAR+ PFFP+L + DQVALLRL+WSEL
Sbjct: 183 AGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSEL 242

Query: 120 FVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEY 179
           FVLNAAQ ++PLH APLLAAAGLHA+PM+A+R VAFMD +R FQEQV+KL  L VDSAEY
Sbjct: 243 FVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEY 302

Query: 180 SCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRT 239
            CLKAI LFT DACGLSD AHVESLQEK+Q AL EYVR+QYP+QP RFG+LLLRLP+LR 
Sbjct: 303 GCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRA 362

Query: 240 VSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 277
           V +S+I QLFF+RLVGKTPIETLIRDMLLSGS+FNWPY
Sbjct: 363 VPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPY 400


>gi|7657395 photoreceptor-specific nuclear receptor isoform b [Homo
           sapiens]
          Length = 410

 Score =  177 bits (449), Expect = 9e-45
 Identities = 92/209 (44%), Positives = 135/209 (64%), Gaps = 5/209 (2%)

Query: 58  YPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWS 117
           +P+S + S     ++  G+++I E +AR+LF AV+WA+N+P F  L   DQV LL   WS
Sbjct: 204 FPSSPYSS-----SSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWS 258

Query: 118 ELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSA 177
           ELF+L A Q S+PL   PLLA     A+  +  R+       R+ QE + + +AL VD  
Sbjct: 259 ELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPT 318

Query: 178 EYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSL 237
           E++C+KA+VLF  +  GL D  HVE+LQ++SQ  L ++ ++ +P+QP RFGKLLL LPSL
Sbjct: 319 EFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSL 378

Query: 238 RTVSSSVIEQLFFVRLVGKTPIETLIRDM 266
           R +++  IE LFF + +G TP+E L+ DM
Sbjct: 379 RFITAERIELLFFRKTIGNTPMEKLLCDM 407


>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
          Length = 463

 Score =  169 bits (429), Expect = 2e-42
 Identities = 93/215 (43%), Positives = 128/215 (59%), Gaps = 2/215 (0%)

Query: 53  LRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALL 112
           L  EP  T  +G   M+ +    + NIC  A + LF+ VEWA+ IP F DL + DQV LL
Sbjct: 244 LAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILL 302

Query: 113 RLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKAL 172
           R  W+EL + + +  S+ +    LLA  GLH    SA          R+  E V K+K +
Sbjct: 303 RAGWNELLIASFSHRSVSVQDGILLAT-GLHVHRSSAHSAGVGSIFDRVLTELVSKMKDM 361

Query: 173 HVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLL 232
            +D +E  CL+AIVLF  DA GLS+ + VE+L+EK    LE Y + +YP QP RF KLLL
Sbjct: 362 QMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLL 421

Query: 233 RLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 267
           RLP+LR++    +E LFF +L+G TPI+T + +ML
Sbjct: 422 RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 456


>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
          Length = 462

 Score =  166 bits (420), Expect = 2e-41
 Identities = 90/214 (42%), Positives = 128/214 (59%), Gaps = 3/214 (1%)

Query: 54  RAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLR 113
           + E Y  +  G     PN+   + NIC+ A + LF+ VEWA+ IP F +L + DQV LLR
Sbjct: 245 KTETYVEANMGLNPSSPND--PVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLR 302

Query: 114 LTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALH 173
             W+EL + + +  S+ +    LLA  GLH    SA          R+  E V K++ + 
Sbjct: 303 AGWNELLIASFSHRSIAVKDGILLAT-GLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQ 361

Query: 174 VDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLR 233
           +D  E  CL+AIVLF  D+ GLS+ A VE+L+EK   +LE Y + +YP QP RF KLLLR
Sbjct: 362 MDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLR 421

Query: 234 LPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 267
           LP+LR++    +E LFF +L+G TPI+T + +ML
Sbjct: 422 LPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455


>gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo
           sapiens]
          Length = 385

 Score =  159 bits (403), Expect = 2e-39
 Identities = 78/200 (39%), Positives = 124/200 (62%), Gaps = 7/200 (3%)

Query: 77  ENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPL 136
           E++CE AAR+LF +++WA+++P F  L + DQ+ LL   W ELFVL  AQ ++P+    L
Sbjct: 183 ESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDANTL 242

Query: 137 LAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFT------- 189
           LA +G++     + ++   +  I+  QE V + + L +D+ E++CLK IV F        
Sbjct: 243 LAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTHSG 302

Query: 190 SDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLF 249
           S+     + A + +LQ+++Q  L  Y+ ++YP QP RFGKLLL LP+LR++S S IE++F
Sbjct: 303 SELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEEVF 362

Query: 250 FVRLVGKTPIETLIRDMLLS 269
           F + +G  PI  L+ DM  S
Sbjct: 363 FKKTIGNVPITRLLSDMYKS 382


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score =  158 bits (399), Expect = 6e-39
 Identities = 86/204 (42%), Positives = 121/204 (59%), Gaps = 3/204 (1%)

Query: 64  GSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLN 123
           G     PN+   + NIC+ A + LF+ VEWA+ IP F  L + DQV LLR  W+EL + +
Sbjct: 326 GGSGSSPND--PVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIAS 383

Query: 124 AAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLK 183
            +  S+ +    LLA  GLH    SA          R+  E V K++ + +D  E  CL+
Sbjct: 384 FSHRSIDVRDGILLAT-GLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLR 442

Query: 184 AIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSS 243
           AI+LF  DA GLS+ + VE L+EK   +LE Y + +YP Q  RF KLLLRLP+LR++   
Sbjct: 443 AIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLK 502

Query: 244 VIEQLFFVRLVGKTPIETLIRDML 267
            +E LFF +L+G TPI+T + +ML
Sbjct: 503 CLEHLFFFKLIGDTPIDTFLMEML 526


>gi|36950991 nuclear receptor subfamily 2, group C, member 2 [Homo
           sapiens]
          Length = 615

 Score =  146 bits (369), Expect = 2e-35
 Identities = 76/196 (38%), Positives = 117/196 (59%), Gaps = 6/196 (3%)

Query: 74  MGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHV 133
           + +  ICE A+R+LF ++ WAR+IP F  L      +L+R  W+ELF L  AQC+  + +
Sbjct: 400 LNVHYICESASRLLFLSMHWARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSL 459

Query: 134 APLLAAAGLHAS------PMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVL 187
           + +LAA   H         +S DR+   M+HI   QE    +  L +D  EY+ LKAIVL
Sbjct: 460 STILAAIVNHLQNSIQEDKLSGDRIKQVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVL 519

Query: 188 FTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQ 247
           F+ D  GL+  + +E  QEK+Q  L++YV+  Y     R  ++L+RLP+LR +SS++ E+
Sbjct: 520 FSPDHPGLTSTSQIEKFQEKAQMELQDYVQKTYSEDTYRLARILVRLPALRLMSSNITEE 579

Query: 248 LFFVRLVGKTPIETLI 263
           LFF  L+G   I+++I
Sbjct: 580 LFFTGLIGNVSIDSII 595


>gi|7706515 photoreceptor-specific nuclear receptor isoform a [Homo
           sapiens]
          Length = 367

 Score =  134 bits (337), Expect = 9e-32
 Identities = 69/169 (40%), Positives = 105/169 (62%), Gaps = 5/169 (2%)

Query: 58  YPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWS 117
           +P+S + S     ++  G+++I E +AR+LF AV+WA+N+P F  L   DQV LL   WS
Sbjct: 204 FPSSPYSS-----SSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWS 258

Query: 118 ELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSA 177
           ELF+L A Q S+PL   PLLA     A+  +  R+       R+ QE + + +AL VD  
Sbjct: 259 ELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPT 318

Query: 178 EYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTR 226
           E++C+KA+VLF  +  GL D  HVE+LQ++SQ  L ++ ++ +P+QP R
Sbjct: 319 EFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVR 367


>gi|189491739 nuclear receptor subfamily 2, group C, member 1
           isoform a [Homo sapiens]
          Length = 603

 Score =  131 bits (330), Expect = 6e-31
 Identities = 72/200 (36%), Positives = 115/200 (57%), Gaps = 6/200 (3%)

Query: 74  MGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHV 133
           + +  I E A+R+LF ++ WA +IP F  L   + ++L++  W+ELF L  AQC   ++V
Sbjct: 388 LNVHYIGESASRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNV 447

Query: 134 APLLAAA------GLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVL 187
           A +LA         L    MS +R    M+HI   QE    +  L +D  EY+ LKAIVL
Sbjct: 448 ATILATFVNCLHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVL 507

Query: 188 FTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQ 247
           F+ D   L ++  +E  QEK+    ++Y+   YP+   R  +LLLRLP+LR +++++ E+
Sbjct: 508 FSPDHPSLENMEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEE 567

Query: 248 LFFVRLVGKTPIETLIRDML 267
           LFF  L+G   I+++I  +L
Sbjct: 568 LFFKGLIGNIRIDSVIPHIL 587


>gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo
           sapiens]
          Length = 464

 Score =  125 bits (313), Expect = 5e-29
 Identities = 77/213 (36%), Positives = 119/213 (55%), Gaps = 7/213 (3%)

Query: 68  MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 127
           ++   I  I ++CE     L   VEWA+ IP F +L + DQVALLR    E  +L A + 
Sbjct: 176 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 235

Query: 128 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 184
           SM      LL    +   H   ++    V+    IRI  E V   + L +D  EY+ LKA
Sbjct: 236 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 291

Query: 185 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 244
           I+ F  DA GLSD   ++ L+ + Q +LE+Y+  +  +   RFG+LLL LP+L++++  +
Sbjct: 292 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 351

Query: 245 IEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 277
           IEQ+ F++L G   I+ L+++MLL GS  + P+
Sbjct: 352 IEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 384


>gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo
           sapiens]
          Length = 474

 Score =  125 bits (313), Expect = 5e-29
 Identities = 77/213 (36%), Positives = 119/213 (55%), Gaps = 7/213 (3%)

Query: 68  MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 127
           ++   I  I ++CE     L   VEWA+ IP F +L + DQVALLR    E  +L A + 
Sbjct: 176 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 235

Query: 128 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 184
           SM      LL    +   H   ++    V+    IRI  E V   + L +D  EY+ LKA
Sbjct: 236 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 291

Query: 185 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 244
           I+ F  DA GLSD   ++ L+ + Q +LE+Y+  +  +   RFG+LLL LP+L++++  +
Sbjct: 292 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 351

Query: 245 IEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 277
           IEQ+ F++L G   I+ L+++MLL GS  + P+
Sbjct: 352 IEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 384


>gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo
           sapiens]
          Length = 442

 Score =  125 bits (313), Expect = 5e-29
 Identities = 77/213 (36%), Positives = 119/213 (55%), Gaps = 7/213 (3%)

Query: 68  MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 127
           ++   I  I ++CE     L   VEWA+ IP F +L + DQVALLR    E  +L A + 
Sbjct: 154 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 213

Query: 128 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 184
           SM      LL    +   H   ++    V+    IRI  E V   + L +D  EY+ LKA
Sbjct: 214 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 269

Query: 185 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 244
           I+ F  DA GLSD   ++ L+ + Q +LE+Y+  +  +   RFG+LLL LP+L++++  +
Sbjct: 270 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 329

Query: 245 IEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 277
           IEQ+ F++L G   I+ L+++MLL GS  + P+
Sbjct: 330 IEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 362


>gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo
           sapiens]
          Length = 452

 Score =  125 bits (313), Expect = 5e-29
 Identities = 77/213 (36%), Positives = 119/213 (55%), Gaps = 7/213 (3%)

Query: 68  MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 127
           ++   I  I ++CE     L   VEWA+ IP F +L + DQVALLR    E  +L A + 
Sbjct: 154 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 213

Query: 128 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 184
           SM      LL    +   H   ++    V+    IRI  E V   + L +D  EY+ LKA
Sbjct: 214 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 269

Query: 185 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 244
           I+ F  DA GLSD   ++ L+ + Q +LE+Y+  +  +   RFG+LLL LP+L++++  +
Sbjct: 270 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 329

Query: 245 IEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 277
           IEQ+ F++L G   I+ L+++MLL GS  + P+
Sbjct: 330 IEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 362


>gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]
          Length = 445

 Score =  125 bits (313), Expect = 5e-29
 Identities = 74/200 (37%), Positives = 118/200 (59%), Gaps = 2/200 (1%)

Query: 73  IMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLH 132
           I  I ++CE   + L   VEWA+ IP F +L + DQVALLR    E  +L A + SM ++
Sbjct: 170 IASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSM-MY 228

Query: 133 VAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDA 192
              LL          S +  ++ + + R+  E V   + + +D  EY+CLKAIV F  DA
Sbjct: 229 KDILLLGNNYVIHRNSCEVEISRVAN-RVLDELVRPFQEIQIDDNEYACLKAIVFFDPDA 287

Query: 193 CGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVR 252
            GLSD   +++++ + Q  LE+Y+  +  +   RFG+LLL LP+L++++  +IEQ+ FV+
Sbjct: 288 KGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVK 347

Query: 253 LVGKTPIETLIRDMLLSGSS 272
           L G   I+ L+++MLL G+S
Sbjct: 348 LFGMVKIDNLLQEMLLGGAS 367


>gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo
           sapiens]
          Length = 417

 Score =  122 bits (305), Expect = 5e-28
 Identities = 75/206 (36%), Positives = 115/206 (55%), Gaps = 7/206 (3%)

Query: 68  MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 127
           ++   I  I ++CE     L   VEWA+ IP F +L + DQVALLR    E  +L A + 
Sbjct: 176 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 235

Query: 128 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 184
           SM      LL    +   H   ++    V+    IRI  E V   + L +D  EY+ LKA
Sbjct: 236 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 291

Query: 185 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 244
           I+ F  DA GLSD   ++ L+ + Q +LE+Y+  +  +   RFG+LLL LP+L++++  +
Sbjct: 292 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 351

Query: 245 IEQLFFVRLVGKTPIETLIRDMLLSG 270
           IEQ+ F++L G   I+ L+++MLL G
Sbjct: 352 IEQIQFIKLFGMAKIDNLLQEMLLGG 377


>gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo
           sapiens]
          Length = 395

 Score =  122 bits (305), Expect = 5e-28
 Identities = 75/206 (36%), Positives = 115/206 (55%), Gaps = 7/206 (3%)

Query: 68  MQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQC 127
           ++   I  I ++CE     L   VEWA+ IP F +L + DQVALLR    E  +L A + 
Sbjct: 154 IRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKR 213

Query: 128 SMPLHVAPLLAAAGL---HASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA 184
           SM      LL    +   H   ++    V+    IRI  E V   + L +D  EY+ LKA
Sbjct: 214 SMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDELVLPFQELQIDDNEYAYLKA 269

Query: 185 IVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSV 244
           I+ F  DA GLSD   ++ L+ + Q +LE+Y+  +  +   RFG+LLL LP+L++++  +
Sbjct: 270 IIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM 329

Query: 245 IEQLFFVRLVGKTPIETLIRDMLLSG 270
           IEQ+ F++L G   I+ L+++MLL G
Sbjct: 330 IEQIQFIKLFGMAKIDNLLQEMLLGG 355


>gi|238550159 estrogen-related receptor beta [Homo sapiens]
          Length = 508

 Score =  117 bits (294), Expect = 9e-27
 Identities = 72/223 (32%), Positives = 113/223 (50%), Gaps = 2/223 (0%)

Query: 45  LSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQ 104
           L+  +S LL AEP          M   +I  +  +C+LA R L   + WA++IP F  L 
Sbjct: 209 LTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLS 268

Query: 105 ITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQE 164
           + DQ++LL+  W E+ +L     S+P      L  A  +       R+   ++  R   +
Sbjct: 269 LGDQMSLLQSAWMEILILGIVYRSLPYD--DKLVYAEDYIMDEEHSRLAGLLELYRAILQ 326

Query: 165 QVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQP 224
            V + K L V+  E+  LKA+ L  SD+  + D+  V+ LQ+    AL++Y  SQ   +P
Sbjct: 327 LVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEP 386

Query: 225 TRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 267
            R GKLLL LP LR  ++  ++  + V+L GK P+  L  +ML
Sbjct: 387 WRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEML 429


>gi|45545405 nuclear receptor subfamily 5, group A, member 2 isoform
           1 [Homo sapiens]
          Length = 541

 Score =  117 bits (292), Expect = 1e-26
 Identities = 69/193 (35%), Positives = 107/193 (55%), Gaps = 5/193 (2%)

Query: 79  ICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAP--- 135
           +C++A + LFS VEWAR+  FF +L++ DQ+ LL+  WSEL +L+     + +H      
Sbjct: 345 MCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQV-VHGKEGSI 403

Query: 136 -LLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACG 194
            L+    +  S +++       + +   QE V KL++L  D  E+ CLK +VLF+ D   
Sbjct: 404 FLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKN 463

Query: 195 LSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLV 254
           L +   VE +QE+   AL +Y    YP Q  +FG+LLLRLP +R +S    E L++  L 
Sbjct: 464 LENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLN 523

Query: 255 GKTPIETLIRDML 267
           G  P   L+ +ML
Sbjct: 524 GDVPYNNLLIEML 536


>gi|4504343 nuclear receptor subfamily 5, group A, member 2 isoform
           2 [Homo sapiens]
          Length = 495

 Score =  117 bits (292), Expect = 1e-26
 Identities = 69/193 (35%), Positives = 107/193 (55%), Gaps = 5/193 (2%)

Query: 79  ICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAP--- 135
           +C++A + LFS VEWAR+  FF +L++ DQ+ LL+  WSEL +L+     + +H      
Sbjct: 299 MCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQV-VHGKEGSI 357

Query: 136 -LLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACG 194
            L+    +  S +++       + +   QE V KL++L  D  E+ CLK +VLF+ D   
Sbjct: 358 FLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREFVCLKFLVLFSLDVKN 417

Query: 195 LSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLV 254
           L +   VE +QE+   AL +Y    YP Q  +FG+LLLRLP +R +S    E L++  L 
Sbjct: 418 LENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQAEEYLYYKHLN 477

Query: 255 GKTPIETLIRDML 267
           G  P   L+ +ML
Sbjct: 478 GDVPYNNLLIEML 490


>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  114 bits (286), Expect = 7e-26
 Identities = 66/219 (30%), Positives = 111/219 (50%), Gaps = 2/219 (0%)

Query: 49  ISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQ 108
           +S LL AEP          +  ++I  +  +C+LA R L   + WA++IP F  L + DQ
Sbjct: 215 VSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQ 274

Query: 109 VALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEK 168
           ++LL+  W E+ +L     S+       L  A  +       ++   +D      + V+K
Sbjct: 275 MSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKK 332

Query: 169 LKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFG 228
            K++ ++  E+  LKAI L  SD+  + DV  V+ LQ+    AL++Y   Q+   P R G
Sbjct: 333 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 392

Query: 229 KLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 267
           K+L+ LP LR  S+  ++  + ++L GK P+  L  +ML
Sbjct: 393 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431


>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  114 bits (286), Expect = 7e-26
 Identities = 66/219 (30%), Positives = 111/219 (50%), Gaps = 2/219 (0%)

Query: 49  ISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQ 108
           +S LL AEP          +  ++I  +  +C+LA R L   + WA++IP F  L + DQ
Sbjct: 215 VSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQ 274

Query: 109 VALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEK 168
           ++LL+  W E+ +L     S+       L  A  +       ++   +D      + V+K
Sbjct: 275 MSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKK 332

Query: 169 LKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFG 228
            K++ ++  E+  LKAI L  SD+  + DV  V+ LQ+    AL++Y   Q+   P R G
Sbjct: 333 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 392

Query: 229 KLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 267
           K+L+ LP LR  S+  ++  + ++L GK P+  L  +ML
Sbjct: 393 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431


>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
           sapiens]
          Length = 458

 Score =  114 bits (286), Expect = 7e-26
 Identities = 66/219 (30%), Positives = 111/219 (50%), Gaps = 2/219 (0%)

Query: 49  ISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQ 108
           +S LL AEP          +  ++I  +  +C+LA R L   + WA++IP F  L + DQ
Sbjct: 238 VSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQ 297

Query: 109 VALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEK 168
           ++LL+  W E+ +L     S+       L  A  +       ++   +D      + V+K
Sbjct: 298 MSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKK 355

Query: 169 LKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFG 228
            K++ ++  E+  LKAI L  SD+  + DV  V+ LQ+    AL++Y   Q+   P R G
Sbjct: 356 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 415

Query: 229 KLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 267
           K+L+ LP LR  S+  ++  + ++L GK P+  L  +ML
Sbjct: 416 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 454


>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  114 bits (286), Expect = 7e-26
 Identities = 66/219 (30%), Positives = 111/219 (50%), Gaps = 2/219 (0%)

Query: 49  ISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQ 108
           +S LL AEP          +  ++I  +  +C+LA R L   + WA++IP F  L + DQ
Sbjct: 215 VSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQ 274

Query: 109 VALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEK 168
           ++LL+  W E+ +L     S+       L  A  +       ++   +D      + V+K
Sbjct: 275 MSLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKK 332

Query: 169 LKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFG 228
            K++ ++  E+  LKAI L  SD+  + DV  V+ LQ+    AL++Y   Q+   P R G
Sbjct: 333 YKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAG 392

Query: 229 KLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 267
           K+L+ LP LR  S+  ++  + ++L GK P+  L  +ML
Sbjct: 393 KMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431


>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
          Length = 423

 Score =  102 bits (253), Expect = 5e-22
 Identities = 71/236 (30%), Positives = 111/236 (47%), Gaps = 6/236 (2%)

Query: 36  GDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWAR 95
           G P    + ++  +S LL  EP              ++  +  +C+L  R +   + WA+
Sbjct: 185 GGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAK 244

Query: 96  NIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAF 155
           +IP F  L ++DQ+++L+  W E+ VL  AQ S+PL     LA A          R    
Sbjct: 245 SIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQ--DELAFAEDLVLDEEGARAAGL 302

Query: 156 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEY 215
            +      + V +L+AL ++  EY  LKA+ L  SD+  + D   VE L+E    AL EY
Sbjct: 303 GELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEY 362

Query: 216 VRSQY----PNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 267
              +       +  R G+LLL LP LR  +  V+   + V+L GK P+  L  +ML
Sbjct: 363 EAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEML 418


>gi|13259503 short heterodimer partner [Homo sapiens]
          Length = 257

 Score = 95.1 bits (235), Expect = 6e-20
 Identities = 70/235 (29%), Positives = 110/235 (46%), Gaps = 11/235 (4%)

Query: 45  LSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQ 104
           L   +S  L+A P P SR   +  +P  +      C  A  +L   V + RN+P F  L 
Sbjct: 21  LYALLSSSLKAVPRPRSRCLCRQHRPVQLCAPHRTCREALDVLAKTVAFLRNLPSFWQLP 80

Query: 105 ITDQVALLRLTWSELFVLNAAQCSMPLHVA----PLLAAAGLHASPMSA-------DRVV 153
             DQ  LL+  W  LF+L  AQ ++   VA    P +    L   P S+       DR  
Sbjct: 81  PQDQRRLLQGCWGPLFLLGLAQDAVTFEVAEAPVPSILKKILLEEPSSSGGSGQLPDRPQ 140

Query: 154 AFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALE 213
             +  ++  Q  +E   +L +   EY+CLK  +LF  D  GL   +H+  LQ+++   L 
Sbjct: 141 PSLAAVQWLQCCLESFWSLELSPKEYACLKGTILFNPDVPGLQAASHIGHLQQEAHWVLC 200

Query: 214 EYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLL 268
           E +    P    R  ++LL   +L+++ +S++  LFF  ++G   I  L+ DMLL
Sbjct: 201 EVLEPWCPAAQGRLTRVLLTASTLKSIPTSLLGDLFFRPIIGDVDIAGLLGDMLL 255


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.135    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,458,079
Number of Sequences: 37866
Number of extensions: 436795
Number of successful extensions: 1381
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1181
Number of HSP's gapped (non-prelim): 133
length of query: 281
length of database: 18,247,518
effective HSP length: 101
effective length of query: 180
effective length of database: 14,423,052
effective search space: 2596149360
effective search space used: 2596149360
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.