Guide to the Human Genome
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Search of human proteins with 223468690

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223468690 hypothetical protein LOC100132994 [Homo sapiens]
         (514 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223468693 hypothetical protein LOC100130361 [Homo sapiens]        1065   0.0  
gi|223468690 hypothetical protein LOC100132994 [Homo sapiens]        1065   0.0  
gi|239752343 PREDICTED: hypothetical protein [Homo sapiens]           728   0.0  
gi|239746856 PREDICTED: hypothetical protein XP_002343859 [Homo ...   728   0.0  
gi|239757832 PREDICTED: hypothetical protein [Homo sapiens]           681   0.0  
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      59   1e-08
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                59   1e-08
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    58   2e-08
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    55   2e-07
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      54   3e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     54   3e-07
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     51   2e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    51   3e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    51   3e-06
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          50   5e-06
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap...    50   5e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        50   5e-06
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ...    50   6e-06
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    50   6e-06
gi|150170670 piccolo isoform 2 [Homo sapiens]                          49   8e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          49   8e-06
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]            48   2e-05
gi|239742467 PREDICTED: double homeobox, 4-like [Homo sapiens]         48   2e-05
gi|116089331 human immunodeficiency virus type I enhancer bindin...    47   3e-05
gi|239744249 PREDICTED: similar to double homeobox, 4 [Homo sapi...    47   4e-05
gi|239744248 PREDICTED: similar to double homeobox, 4 [Homo sapi...    47   4e-05
gi|239744244 PREDICTED: similar to double homeobox, 4 [Homo sapi...    47   4e-05
gi|239744242 PREDICTED: similar to double homeobox, 4 [Homo sapi...    47   4e-05
gi|239744240 PREDICTED: similar to double homeobox, 4 [Homo sapi...    47   4e-05
gi|54860105 nadrin isoform 2 [Homo sapiens]                            47   4e-05

>gi|223468693 hypothetical protein LOC100130361 [Homo sapiens]
          Length = 514

 Score = 1065 bits (2754), Expect = 0.0
 Identities = 514/514 (100%), Positives = 514/514 (100%)

Query: 1   MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG 60
           MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG
Sbjct: 1   MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG 60

Query: 61  FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP 120
           FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP
Sbjct: 61  FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP 120

Query: 121 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS 180
           EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS
Sbjct: 121 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS 180

Query: 181 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS 240
           RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS
Sbjct: 181 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS 240

Query: 241 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC 300
           RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC
Sbjct: 241 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC 300

Query: 301 SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV 360
           SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV
Sbjct: 301 SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV 360

Query: 361 RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS 420
           RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS
Sbjct: 361 RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS 420

Query: 421 VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG 480
           VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG
Sbjct: 421 VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG 480

Query: 481 AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514
           AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL
Sbjct: 481 AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514


>gi|223468690 hypothetical protein LOC100132994 [Homo sapiens]
          Length = 514

 Score = 1065 bits (2754), Expect = 0.0
 Identities = 514/514 (100%), Positives = 514/514 (100%)

Query: 1   MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG 60
           MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG
Sbjct: 1   MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG 60

Query: 61  FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP 120
           FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP
Sbjct: 61  FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP 120

Query: 121 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS 180
           EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS
Sbjct: 121 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS 180

Query: 181 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS 240
           RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS
Sbjct: 181 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS 240

Query: 241 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC 300
           RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC
Sbjct: 241 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC 300

Query: 301 SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV 360
           SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV
Sbjct: 301 SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV 360

Query: 361 RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS 420
           RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS
Sbjct: 361 RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS 420

Query: 421 VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG 480
           VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG
Sbjct: 421 VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG 480

Query: 481 AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514
           AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL
Sbjct: 481 AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514


>gi|239752343 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 518

 Score =  728 bits (1878), Expect = 0.0
 Identities = 373/518 (72%), Positives = 407/518 (78%), Gaps = 4/518 (0%)

Query: 1   MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGV----PGSGDGKSESGFT 56
           MSS D+VSVC AG   EGG++AG+ TASPGAP    HG DL       G G GK ESGFT
Sbjct: 1   MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60

Query: 57  DPEGFSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQG 116
           DPE FSFESESELIEQGRVVLWG+EGRPGTPVDDQ    DYSFYLADEPA I+PP SVQG
Sbjct: 61  DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120

Query: 117 HPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPER 176
           HP PEGA A+GS + WAD EVGPS R  L  SPG+WQQASAG LHL  PGP  AW+NPER
Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180

Query: 177 GSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKR 236
           GSKSR S +VDPQQPSA+GP  L T DSDSADESSDLP+++V I   EGSQAKPGSPKK 
Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240

Query: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296
            DT  + SFH +ESYL V G  L S PR LTPV ERPAVGEL+    KKMQS  WGK  V
Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300

Query: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356
           RPSCSGAA  G LP+G   RK+A  KKSL GA +LAL   FPA G+RLSA PP+PA+FPP
Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360

Query: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416
            SGV   G S +P++PKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT +P L
Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420

Query: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476
             LSVRRGE+SS DPNIRAPQ+ GTS+PSA++   LVPR HA SG+ QPPVHPPRPERQQ
Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480

Query: 477 QPPGAQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514
           QPPGAQGCPRCI LQREIEDL  QLAAMQFLTDKFQDL
Sbjct: 481 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL 518


>gi|239746856 PREDICTED: hypothetical protein XP_002343859 [Homo
           sapiens]
          Length = 518

 Score =  728 bits (1878), Expect = 0.0
 Identities = 373/518 (72%), Positives = 407/518 (78%), Gaps = 4/518 (0%)

Query: 1   MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGV----PGSGDGKSESGFT 56
           MSS D+VSVC AG   EGG++AG+ TASPGAP    HG DL       G G GK ESGFT
Sbjct: 1   MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60

Query: 57  DPEGFSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQG 116
           DPE FSFESESELIEQGRVVLWG+EGRPGTPVDDQ    DYSFYLADEPA I+PP SVQG
Sbjct: 61  DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120

Query: 117 HPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPER 176
           HP PEGA A+GS + WAD EVGPS R  L  SPG+WQQASAG LHL  PGP  AW+NPER
Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180

Query: 177 GSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKR 236
           GSKSR S +VDPQQPSA+GP  L T DSDSADESSDLP+++V I   EGSQAKPGSPKK 
Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240

Query: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296
            DT  + SFH +ESYL V G  L S PR LTPV ERPAVGEL+    KKMQS  WGK  V
Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300

Query: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356
           RPSCSGAA  G LP+G   RK+A  KKSL GA +LAL   FPA G+RLSA PP+PA+FPP
Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360

Query: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416
            SGV   G S +P++PKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT +P L
Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420

Query: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476
             LSVRRGE+SS DPNIRAPQ+ GTS+PSA++   LVPR HA SG+ QPPVHPPRPERQQ
Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480

Query: 477 QPPGAQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514
           QPPGAQGCPRCI LQREIEDL  QLAAMQFLTDKFQDL
Sbjct: 481 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL 518


>gi|239757832 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 503

 Score =  681 bits (1756), Expect = 0.0
 Identities = 348/490 (71%), Positives = 382/490 (77%), Gaps = 4/490 (0%)

Query: 1   MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGV----PGSGDGKSESGFT 56
           MSS D+VSVC AG   EGG++AG+ TASPGAP    HG DL       G G GK ESGFT
Sbjct: 1   MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60

Query: 57  DPEGFSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQG 116
           DPE FSFESESELIEQGRVVLWG+EGRPGTPVDDQ    DYSFYLADEPA I+PP SVQG
Sbjct: 61  DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120

Query: 117 HPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPER 176
           HP PEGA A+GS + WAD EVGPS R  L  SPG+WQQASAG LHL  PGP  AW+NPER
Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180

Query: 177 GSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKR 236
           GSKSR S +VDPQQPSA+GP  L T DSDSADESSDLP+++V I   EGSQAKPGSPKK 
Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240

Query: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296
            DT  + SFH +ESYL V G  L S PR LTPV ERPAVGEL+    KKMQS  WGK  V
Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300

Query: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356
           RPSCSGAA  G LP+G   RK+A  KKSL GA +LAL   FPA G+RLSA PP+PA+FPP
Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360

Query: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416
            SGV   G S +P++PKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT +P L
Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420

Query: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476
             LSVRRGE+SS DPNIRAPQ+ GTS+PSA++   LVPR HA SG+ QPPVHPPRPERQQ
Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480

Query: 477 QPPGAQGCPR 486
           QPPGAQGCPR
Sbjct: 481 QPPGAQGCPR 490


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 127/503 (25%), Positives = 157/503 (31%), Gaps = 69/503 (13%)

Query: 29   PGAPGAHSHGLDLGVPGSG-----DGKSES----GFTDPEGFSFE--SESELIEQGRVVL 77
            PG PG      D GVPG       +GK       G   P G +    S+ E    G V  
Sbjct: 569  PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 628

Query: 78   WGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAE--GSAENWADA 135
             G +G PG P    G   +     AD  A    PP +QG P  EG       S       
Sbjct: 629  KGDQGHPGVP-GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 687

Query: 136  EVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNP----ERGSKSRWSLRVDPQQP 191
            E G  GRD     PG+  +A    L    PGP  A   P      G       R +    
Sbjct: 688  EEGKEGRDGKPGPPGEPGKAGEPGL----PGPEGARGPPGFKGHTGDSGAPGPRGESGAM 743

Query: 192  SAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESY 251
               G   LP  D D+       P    G     GS   PG P   + T  Q     +   
Sbjct: 744  GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP-SGTPGQKGSKGENGS 802

Query: 252  LPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQ 311
              +PG FL   PRG         V   E  P K  +    G+    P   G       P 
Sbjct: 803  PGLPG-FL--GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGE-RGDPGIKGDKG----PP 854

Query: 312  GLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKP-Q 370
            G   +    G     G + L   +G P  GE     PP P   P F G+R +  S +  +
Sbjct: 855  GGKGQPGDPGIPGHKGHTGLMGPQGLP--GENGPVGPPGPPGQPGFPGLRGESPSMETLR 912

Query: 371  KPKHSSPGKKPAGRKT-----------RESQAAAREDNDPNRDEVPRAQLPTHRPGLPRL 419
            +      GK+   R             + SQ        P +D +P    P   PG P  
Sbjct: 913  RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQ 972

Query: 420  SVRRGEFSSSDP-------------------NIRAPQLPGTSEPSAYSPGGLVPRRHAPS 460
                G      P                    +  P +PG      Y+  GL P    P 
Sbjct: 973  GGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL-PGIPGPQ 1031

Query: 461  GNQQPPVHPPRPERQQQPPGAQG 483
            G   P  HP  P     PPG  G
Sbjct: 1032 GETGPAGHPGLP----GPPGPPG 1050



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 49/184 (26%), Positives = 65/184 (35%), Gaps = 28/184 (15%)

Query: 13  GFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQ 72
           G   E GK+   R   PG PG      + G+PG    +   GF    G S  +     E 
Sbjct: 684 GIPGEEGKEG--RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS-GAPGPRGES 740

Query: 73  GRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENW 132
           G + L G+EG PG   D                     P   QG   P G   +  +   
Sbjct: 741 GAMGLPGQEGLPGKDGD-------------------TGPTGPQGPQGPRGPPGKNGSPG- 780

Query: 133 ADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGP-GPVRAWKNPERGSKSRWSLRVDPQQP 191
           +  E GPSG    G    K +  S G     GP GP    +  E+G   +  +   P +P
Sbjct: 781 SPGEPGPSGTP--GQKGSKGENGSPGLPGFLGPRGP--PGEPGEKGVPGKEGVPGKPGEP 836

Query: 192 SAKG 195
             KG
Sbjct: 837 GFKG 840



 Score = 36.2 bits (82), Expect = 0.073
 Identities = 117/522 (22%), Positives = 157/522 (30%), Gaps = 132/522 (25%)

Query: 29  PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFS--FESESELIEQGRVVLWGREGRPGT 86
           PG PG      + G+ G    K E+G     GF      + +  E+G + L G +G  G 
Sbjct: 261 PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 320

Query: 87  -----PVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAE-----NWADAE 136
                P    G        L    +   P P + G   P+G   +              E
Sbjct: 321 KGEAGPAGPPG--------LPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGE 372

Query: 137 VGPSGRDVLGHSPGKWQQASAGRL----------HLCGPGPV-------------RAWKN 173
           +GP G    G    K Q+ + G            H+  PGP                 K+
Sbjct: 373 LGPQG--PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKD 430

Query: 174 PERGSKSR---------WSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNE 224
            ERG K              R DP  P   GP             S  LP   +G   + 
Sbjct: 431 GERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLP-GPLGTKGDR 489

Query: 225 GSQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQK 284
           G+   PGSP  R D                PG  +   P    P  ++ + G        
Sbjct: 490 GAPGIPGSPGSRGD----------------PGIGVAGPPGPSGPPGDKGSPG-------- 525

Query: 285 KMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERL 344
              SR        P   G       PQG + R       S G  + LA       C +  
Sbjct: 526 ---SRG------LPGFPG-------PQGPAGRDGLSSLLSPGDINLLAK----DVCND-- 563

Query: 345 SAAPPEPATFPPFSGVRPQGMSKKPQKP-KHSSPGKK----------------PAGRK-T 386
              PP P   P   G +  G    P KP +  + GKK                P G +  
Sbjct: 564 --CPPGPPGLPGLPGFK--GDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGE 619

Query: 387 RESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPG-TSEPS 445
           R +     +  D     VP    P   PG P      G  ++  P I+    PG    P 
Sbjct: 620 RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG--AAGPPGIQGS--PGKEGPPG 675

Query: 446 AYSPGGL--VPRRHAPSGNQQPPVHPPRPERQQQP--PGAQG 483
              P GL  +P      G    P  P  P +  +P  PG +G
Sbjct: 676 PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG 717


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 127/503 (25%), Positives = 157/503 (31%), Gaps = 69/503 (13%)

Query: 29   PGAPGAHSHGLDLGVPGSG-----DGKSES----GFTDPEGFSFE--SESELIEQGRVVL 77
            PG PG      D GVPG       +GK       G   P G +    S+ E    G V  
Sbjct: 1122 PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 1181

Query: 78   WGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAE--GSAENWADA 135
             G +G PG P    G   +     AD  A    PP +QG P  EG       S       
Sbjct: 1182 KGDQGHPGVP-GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 1240

Query: 136  EVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNP----ERGSKSRWSLRVDPQQP 191
            E G  GRD     PG+  +A    L    PGP  A   P      G       R +    
Sbjct: 1241 EEGKEGRDGKPGPPGEPGKAGEPGL----PGPEGARGPPGFKGHTGDSGAPGPRGESGAM 1296

Query: 192  SAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESY 251
               G   LP  D D+       P    G     GS   PG P   + T  Q     +   
Sbjct: 1297 GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP-SGTPGQKGSKGENGS 1355

Query: 252  LPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQ 311
              +PG FL   PRG         V   E  P K  +    G+    P   G       P 
Sbjct: 1356 PGLPG-FL--GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGE-RGDPGIKGDKG----PP 1407

Query: 312  GLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKP-Q 370
            G   +    G     G + L   +G P  GE     PP P   P F G+R +  S +  +
Sbjct: 1408 GGKGQPGDPGIPGHKGHTGLMGPQGLP--GENGPVGPPGPPGQPGFPGLRGESPSMETLR 1465

Query: 371  KPKHSSPGKKPAGRKT-----------RESQAAAREDNDPNRDEVPRAQLPTHRPGLPRL 419
            +      GK+   R             + SQ        P +D +P    P   PG P  
Sbjct: 1466 RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQ 1525

Query: 420  SVRRGEFSSSDP-------------------NIRAPQLPGTSEPSAYSPGGLVPRRHAPS 460
                G      P                    +  P +PG      Y+  GL P    P 
Sbjct: 1526 GGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL-PGIPGPQ 1584

Query: 461  GNQQPPVHPPRPERQQQPPGAQG 483
            G   P  HP  P     PPG  G
Sbjct: 1585 GETGPAGHPGLP----GPPGPPG 1603



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 49/184 (26%), Positives = 65/184 (35%), Gaps = 28/184 (15%)

Query: 13   GFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQ 72
            G   E GK+   R   PG PG      + G+PG    +   GF    G S  +     E 
Sbjct: 1237 GIPGEEGKEG--RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS-GAPGPRGES 1293

Query: 73   GRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENW 132
            G + L G+EG PG   D                     P   QG   P G   +  +   
Sbjct: 1294 GAMGLPGQEGLPGKDGD-------------------TGPTGPQGPQGPRGPPGKNGSPG- 1333

Query: 133  ADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGP-GPVRAWKNPERGSKSRWSLRVDPQQP 191
            +  E GPSG    G    K +  S G     GP GP    +  E+G   +  +   P +P
Sbjct: 1334 SPGEPGPSGTP--GQKGSKGENGSPGLPGFLGPRGP--PGEPGEKGVPGKEGVPGKPGEP 1389

Query: 192  SAKG 195
              KG
Sbjct: 1390 GFKG 1393



 Score = 37.4 bits (85), Expect = 0.033
 Identities = 52/191 (27%), Positives = 67/191 (35%), Gaps = 37/191 (19%)

Query: 321 GKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVR----PQGMSKKP-QKPKHS 375
           G    GG+  L    GFP         PP P   P   G      P G   +P ++ +  
Sbjct: 723 GPPGPGGSPGLPGEIGFPG-----KPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDG 777

Query: 376 SPGKKPAGRKTRESQAAAREDNDPNRDEVPRA------------QLPTHRPGLPRLSVRR 423
            PGK P  R     Q  A    +     +P A            Q      GLP L   R
Sbjct: 778 LPGK-PGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDR 836

Query: 424 GEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQ------ 477
           GE   + P    P LPGT+  S ++P   +P    P G +  P  P  P  Q +      
Sbjct: 837 GEKGEAGP-AGPPGLPGTT--SLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGP 893

Query: 478 -----PPGAQG 483
                PPGA+G
Sbjct: 894 QGPTGPPGAKG 904


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 58/200 (29%), Positives = 74/200 (37%), Gaps = 14/200 (7%)

Query: 292 GKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPP-- 349
           GK +  P   G    G  P G  +     G KS    S     +G P  G      PP  
Sbjct: 55  GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 114

Query: 350 --EPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRA 407
             +P   PP  G RPQG    P KP+    G  P G K+R  ++   +   P      + 
Sbjct: 115 PGKPQGPPPQGGNRPQG-PPPPGKPQ----GPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 169

Query: 408 QLPTHRPGLPRLSVRRGEFSSSDP----NIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQ 463
           Q P   PG P+    +G      P      + P   G    S+ SP G  P+   P G  
Sbjct: 170 QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGK-PQGPPPQGGN 228

Query: 464 QPPVHPPRPERQQQPPGAQG 483
           QP   PP P + Q PP   G
Sbjct: 229 QPQGPPPPPGKPQGPPPQGG 248



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 67/243 (27%), Positives = 87/243 (35%), Gaps = 19/243 (7%)

Query: 253 PVPGRFLTSAPRGLTPVAERPAVGELEDSP-----QKKMQSRAWGKVEVRPSCSGAAAAG 307
           P PG+     P+G    + R   G+ +  P     Q +      GK +  P   G    G
Sbjct: 72  PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131

Query: 308 ALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSK 367
             P G  +     G KS    S     +G P  G      PP P   P   G  PQG  K
Sbjct: 132 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQG-GK 188

Query: 368 KPQKPKHSSPGKK----PAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRR 423
           KPQ P    PGK     P G K+R SQ+   +   P      + Q P   PG P+    +
Sbjct: 189 KPQGPP--PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 246

Query: 424 GEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483
           G    + P  + P  PG  +      G       +P G  Q P        Q  PP A G
Sbjct: 247 G---GNKP--QGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG 301

Query: 484 CPR 486
            P+
Sbjct: 302 NPQ 304



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 45/153 (29%), Positives = 58/153 (37%), Gaps = 13/153 (8%)

Query: 338 PACGERLSAAPPEPATF---PPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAR 394
           P  G +    PP P      PP  G +PQG    P KP+    G  P G K+R  ++   
Sbjct: 41  PQGGNKPQGPPPPPGKPQGPPPQGGNKPQG-PPPPGKPQ----GPPPQGDKSRSPRSPPG 95

Query: 395 EDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDP----NIRAPQLPGTSEPSAYSPG 450
           +   P      + Q P   PG P+    +G      P      + P   G    S  SP 
Sbjct: 96  KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPP 155

Query: 451 GLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483
           G  P+   P G  QP   PP P + Q PP   G
Sbjct: 156 GK-PQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 187



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 68/297 (22%), Positives = 93/297 (31%), Gaps = 39/297 (13%)

Query: 188 PQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHC 247
           PQ P   G  + P    D +      P    G     G+Q +   P              
Sbjct: 68  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 127

Query: 248 KESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSP-----QKKMQSRAWGKVEVRPSCSG 302
           +    P PG+     P+G    + R   G+ +  P     Q +      GK +  P   G
Sbjct: 128 RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 187

Query: 303 AAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRP 362
               G  P G  +     G KS    S     +G P  G      PP P   P   G  P
Sbjct: 188 KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPP 245

Query: 363 QGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVR 422
           QG   KPQ P    P  KP G   +    +    + P + + P  Q   +  G P     
Sbjct: 246 QG-GNKPQGP---PPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP----- 296

Query: 423 RGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPP 479
                 +  N + PQ P                   P+G  Q P  PP+  R  +PP
Sbjct: 297 ----PPAGGNPQQPQAP-------------------PAGQPQGPPRPPQGGRPSRPP 330



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 48/209 (22%), Positives = 63/209 (30%), Gaps = 12/209 (5%)

Query: 188 PQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHC 247
           PQ P   G  + P    D +      P    G     G+Q +   P              
Sbjct: 129 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188

Query: 248 KESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSP-----QKKMQSRAWGKVEVRPSCSG 302
           K    P PG+     P+G    + +   G+ +  P     Q +      GK +  P   G
Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 248

Query: 303 AAAAGALPQGLSRRKMA-GGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVR 361
               G  P G  +   A GG KS    S     +G P         PP PA      G  
Sbjct: 249 NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA------GGN 302

Query: 362 PQGMSKKPQKPKHSSPGKKPAGRKTRESQ 390
           PQ     P       P     GR +R  Q
Sbjct: 303 PQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 60/223 (26%), Positives = 76/223 (34%), Gaps = 28/223 (12%)

Query: 292 GKVEVRPSCSGAAAAGALPQGLSRR--KMAGGKKSLGGASQLALGRGFPACGERLSAAPP 349
           GK E RP   G  + G  P+          GG +S G   +     G P  G   S  PP
Sbjct: 55  GKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPP 114

Query: 350 ----EPATFPPFSGVRPQGMSKKPQKPKHSSPGK------------KPAGRKTRESQAAA 393
               +P   PP  G + QG   +P KP+   P              KP G   +    + 
Sbjct: 115 PRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 174

Query: 394 REDNDPNRDEVP------RAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAY 447
                P + E P      ++Q P  RPG P     +G   S  P  R  +  G       
Sbjct: 175 GPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGN 234

Query: 448 SPGGLVPRRHAPSG----NQQPPVHPPRPERQQQPPGAQGCPR 486
            P G  P    P G        P  PP P R Q PP   G P+
Sbjct: 235 KPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQ 277



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 62/232 (26%), Positives = 82/232 (35%), Gaps = 19/232 (8%)

Query: 263 PRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRR--KMAG 320
           PR   P    P  G     P  +      GK E +P   G  + G  P+          G
Sbjct: 73  PRPGKPEGPPPQGGNQSQGPPPRP-----GKPEGQPPQGGNQSQGPPPRPGKPEGPPPQG 127

Query: 321 GKKSLGGASQLALGRGFPACGERLSAAPP----EPATFPPFSGVRPQGMSKKPQKPKHSS 376
           G +S G   +     G P  G   S  PP    +P   PP  G + QG    P KP+   
Sbjct: 128 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPP 187

Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRG--EFSSSDPNIR 434
           P     G +++       +   P      ++Q P  RPG P     +G  +     P+  
Sbjct: 188 P---QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPG 244

Query: 435 APQLPGTSE---PSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483
            PQ P   E   P    P G       P GN Q P+ PP  + Q  PP  QG
Sbjct: 245 KPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQG 296



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 61/230 (26%), Positives = 82/230 (35%), Gaps = 27/230 (11%)

Query: 263 PRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRR--KMAG 320
           PR   P  + P  G     P  +      GK E  P   G  + G  P+          G
Sbjct: 94  PRPGKPEGQPPQGGNQSQGPPPRP-----GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG 148

Query: 321 GKKSLGGASQLALGRGFPACGERLSAAPP----EPATFPPFSGVRPQGMSKKPQKPKHSS 376
           G +S G   +     G P  G   S  PP    +P   PP  G + QG   +P KP+   
Sbjct: 149 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 208

Query: 377 P--GKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIR 434
           P  G +  G   R  +         N+ + P    P H PG P+     G         +
Sbjct: 209 PQGGNQSQGPPPRPGKPEGPPSQGGNKPQGP----PPH-PGKPQ-----GPPPQEGNKPQ 258

Query: 435 APQLPGTSEPSAYSPGGLVPRRHAP--SGNQQPPVHPPRPERQQQPPGAQ 482
            P  PG   P    P G  P++  P  +G  Q P  PP+  R  +PP  Q
Sbjct: 259 RPPPPG--RPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQ 306



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 44/162 (27%), Positives = 59/162 (36%), Gaps = 23/162 (14%)

Query: 342 ERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSP--GKKPAGRKTRESQAAAREDNDP 399
           +R    P +P   PP  G + QG   +P KP+   P  G +  G   R  +   +     
Sbjct: 48  QRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGG 107

Query: 400 NRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAP 459
           N     ++Q P  RPG P     +G   S  P  R  +  G          G  PR   P
Sbjct: 108 N-----QSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 162

Query: 460 SG--------NQQPPVHPPRPE--------RQQQPPGAQGCP 485
            G        +Q PP HP +PE        + Q PP   G P
Sbjct: 163 EGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKP 204



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 2/56 (3%)

Query: 428 SSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483
           S  P  R PQ  G ++P    P    P    P G  Q    PPRP + + PP   G
Sbjct: 33  SGKPEGRRPQ--GGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGG 86


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 122/471 (25%), Positives = 146/471 (30%), Gaps = 55/471 (11%)

Query: 29  PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88
           PGA GA+      G PG    +  SG   P G                  G  G PG P 
Sbjct: 394 PGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPK-------------GNSGEPGAP- 439

Query: 89  DDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHS 148
             +GD          EP     P  VQG P P G   +  A      E GP+G   L   
Sbjct: 440 GSKGDTG-----AKGEPG----PVGVQGPPGPAGEEGKRGARG----EPGPTG---LPGP 483

Query: 149 PGKWQQASAGRLHLCGPGPVRAWKNP--ERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDS 206
           PG  ++   G     G   V   K P  ERGS      +  P +    G   LP     +
Sbjct: 484 PG--ERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541

Query: 207 ADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQA--SFHCKESYLPVPG----RFLT 260
               S  P  K G     G   +PG P       +     F   +     PG    R + 
Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601

Query: 261 SAPRGLTPVAERPAVG-ELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMA 319
             P  + P  +    G +    P      R        P   G       P    +    
Sbjct: 602 GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ 661

Query: 320 GGKKSLG--GASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSP 377
           G    LG  G S     RGFP  GER    PP PA  P  +   P     K       +P
Sbjct: 662 GVPGDLGAPGPSGARGERGFP--GERGVQGPPGPAG-PRGANGAPGNDGAKGDAGAPGAP 718

Query: 378 GKKPA-GRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPN--IR 434
           G + A G +    +  A     P  D       P    G P     RG      P     
Sbjct: 719 GSQGAPGLQGMPGERGAAGLPGPKGDRGDAG--PKGADGSPGKDGVRGLTGPIGPPGPAG 776

Query: 435 APQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485
           AP   G S PS   P G    R AP    +P   PP P     PPGA G P
Sbjct: 777 APGDKGESGPSG--PAGPTGARGAPGDRGEPG--PPGPAGFAGPPGADGQP 823



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 127/528 (24%), Positives = 160/528 (30%), Gaps = 121/528 (22%)

Query: 30   GAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPVD 89
            G PG      DLG PG    + E GF    G           QG     G  G  G P +
Sbjct: 656  GKPGEQGVPGDLGAPGPSGARGERGFPGERGV----------QGPPGPAGPRGANGAPGN 705

Query: 90   D--QGDVVDYSFYLADEPAA--IVPPPSVQGHPFPEGAAA-EGSAENWADAEVGPSGRDV 144
            D  +GD        A  P A      P +QG P   GAA   G   +  DA  GP G D 
Sbjct: 706  DGAKGD--------AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDA--GPKGAD- 754

Query: 145  LGHSPGK-WQQASAGRLHLCGPGPVRAWKNPE--------RGSKSRWSLRVDPQQPSAKG 195
               SPGK   +   G +   GP      K            G++     R +P  P   G
Sbjct: 755  --GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812

Query: 196  PTRLPTHDSD--SADESSDL-------------------PLMKVGICRNEGSQAKPGSPK 234
                P  D    +  E  D                    P+  VG    +G++   G P 
Sbjct: 813  FAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872

Query: 235  KRADTSRQA-------SFHCKESYLPVP-GRFLTSAPRGLTPVAERPAVGELEDSPQKKM 286
                            S +      P P G+     PRG T  A RP        P    
Sbjct: 873  ATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAG 932

Query: 287  QSRAWGKVEVRPSCSGAAAAGALP--QGLSRRKMAGGKKSLGGASQLALGRGFP------ 338
            +  +       P   G A A   P  QG++      G++ + G       RGFP      
Sbjct: 933  EKGS-------PGADGPAGAPGTPGPQGIA------GQRGVVGLPGQRGERGFPGLPGPS 979

Query: 339  ----------ACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKP-KHSSPGK--KPAGRK 385
                      A GER    PP P   P  +G  P G S +   P    SPG+   P  + 
Sbjct: 980  GEPGKQGPSGASGER---GPPGPMGPPGLAG--PPGESGREGAPGAEGSPGRDGSPGAKG 1034

Query: 386  TRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDP----------NIRA 435
             R     A     P     P    P  + G       RGE   + P              
Sbjct: 1035 DRGETGPAGPPGAPGAPGAPGPVGPAGKSG------DRGETGPAGPAGPVGPVGARGPAG 1088

Query: 436  PQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483
            PQ P   +      G    + H      Q P  PP    +Q P GA G
Sbjct: 1089 PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASG 1136



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 119/505 (23%), Positives = 159/505 (31%), Gaps = 64/505 (12%)

Query: 17   EGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVV 76
            +G   A     S GAPG      + G  G    K + G   P+G    ++    + G   
Sbjct: 709  KGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKG----ADGSPGKDGVRG 764

Query: 77   LWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAE 136
            L G  G PG P    GD  +        P      P  +G P P G A        AD +
Sbjct: 765  LTGPIGPPG-PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPG-ADGQ 822

Query: 137  VGPSGRDVLGHSPGKWQQASAGRLHLCG-PGPVRAWKNP----ERGSKSRWSL------- 184
             G  G    G +  K      G     G PGP+     P     RGS             
Sbjct: 823  PGAKGEP--GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880

Query: 185  -RVDPQQPSAK-GPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQ 242
             RV P  PS   GP   P     +  E    P  + G     G    PG P    +    
Sbjct: 881  GRVGPPGPSGNAGP---PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSP 937

Query: 243  ASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV-RPSCS 301
             +    +     PG   T  P+G+    +R  VG      ++          E  +   S
Sbjct: 938  GA----DGPAGAPG---TPGPQGI--AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPS 988

Query: 302  GAAAAGALPQGLSRRKMAG-----GKKSLGGASQLALGRGFP-ACGERLSAAPPEPATFP 355
            GA+     P  +    +AG     G++   GA       G P A G+R    P  P   P
Sbjct: 989  GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048

Query: 356  PFSG----VRPQGMSKKPQKPKHSSPGKK--PAGRKTRESQAAAREDNDPNRDEVPRAQL 409
               G    V P G S    +   + P     P G +        R D     ++  R  +
Sbjct: 1049 GAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRG-I 1107

Query: 410  PTHR--------PGLPRLSVRRGEFSSSDP-NIRAPQLPGTSEPSAYS-----PGGLVPR 455
              HR        PG P     +G   +S P   R P  PG++           PG + P 
Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGP--PGSAGAPGKDGLNGLPGPIGPP 1165

Query: 456  RHAPSGNQQPPVHPPRPERQQQPPG 480
                      PV PP P     PPG
Sbjct: 1166 GPRGRTGDAGPVGPPGPPGPPGPPG 1190


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 59/199 (29%), Positives = 72/199 (36%), Gaps = 10/199 (5%)

Query: 292 GKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEP 351
           GK +  P   G    G  P G  +     G KS    S     +G P  G      PP P
Sbjct: 76  GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 135

Query: 352 ATFPPFSGVRPQGMSKKPQKPKHSSP-GKKPAG-RKTRESQAAAREDNDPNRDEVPRAQL 409
              P   G  PQG +K    P    P G  P G  K+R S++   +   P      + Q 
Sbjct: 136 PGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQG 193

Query: 410 PTHRPGLPR-LSVRRGEFSSSDPNIRAPQLP----GTSEPSAYSPGGLVPRRHAPSGNQQ 464
           P   PG P+    + G      P    PQ P         SA SP G  P+   P G  Q
Sbjct: 194 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG-KPQGPPPQGGNQ 252

Query: 465 PPVHPPRPERQQQPPGAQG 483
           P   PP P + Q PP   G
Sbjct: 253 PQGPPPPPGKPQGPPPQGG 271



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 70/262 (26%), Positives = 98/262 (37%), Gaps = 32/262 (12%)

Query: 253 PVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAW----GKVEVRPSCSGAAAAGA 308
           P PG+     P+G       P  G+ +  P +  +SR+     GK +  P   G    G 
Sbjct: 73  PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 132

Query: 309 LPQ-GLSRRKMAGGKKSLGGASQLALGRGFPACGE---RLSAAPP-EPATFPPFSGVRPQ 363
            P  G  +     G     G       +G P  G+   R S +PP +P   PP  G +PQ
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192

Query: 364 GMSKKPQKPKHSSP--GKKPAG---------------RKTRESQAAAREDNDPNRDEVPR 406
           G    P KP+   P  G KP G                K++ +++   +   P      +
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ 252

Query: 407 AQLPTHRPGLPR-LSVRRGEFSSSDPNIRAPQLP----GTSEPSAYSPGGLVPRRHAPSG 461
            Q P   PG P+    + G      P    PQ P    G+   S+ SP G  P+   P G
Sbjct: 253 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK-PQGPPPQG 311

Query: 462 NQQPPVHPPRPERQQQPPGAQG 483
             QP   PP P + Q PP   G
Sbjct: 312 GNQPQGPPPPPGKPQGPPPQGG 333



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 47/175 (26%), Positives = 60/175 (34%), Gaps = 28/175 (16%)

Query: 335 RGFPACGERLSAAPPEPATFP----PFSGVRPQGMSKKPQKPKHSSP------------- 377
           +G P  G      PP P   P    P  G +PQG    P KP+   P             
Sbjct: 37  QGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 96

Query: 378 ---GKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPR------LSVRRGEFSS 428
              G  P G K+R  ++   +   P      + Q P   PG P+       +  +G    
Sbjct: 97  KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 156

Query: 429 SDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483
             P    PQ    S  S   PG   P+   P G  QP   PP P + Q PP   G
Sbjct: 157 GKPQGPPPQGDNKSRSSRSPPG--KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 209



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 94/380 (24%), Positives = 118/380 (31%), Gaps = 46/380 (12%)

Query: 115 QGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQ--QASAGRLHLCGPGPVRAWK 172
           QG P P G   +G      +   GP         PGK Q      G      P P +   
Sbjct: 48  QGPPSPPGKP-QGPPPQGGNQPQGPPP------PPGKPQGPPPQGGNKPQGPPPPGKPQG 100

Query: 173 NPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAK-PG 231
            P +G KSR      P+ P  K P   P    +        P    G     G++ + P 
Sbjct: 101 PPPQGDKSR-----SPRSPPGK-PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 154

Query: 232 SPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAW 291
            P K      Q     + S  P PG+          P    P  G     P         
Sbjct: 155 PPGKPQGPPPQGDNKSRSSRSP-PGK----------PQGPPPQGGNQPQGPPPPP----- 198

Query: 292 GKVEVRPSCSGAAAAGALPQGLSRRKMA-GGKKSLGGASQLALGRGFPACGERLSAAPPE 350
           GK +  P   G    G  P G  +     G  KS    S     +G P  G      PP 
Sbjct: 199 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP 258

Query: 351 PATFPPFSGVRPQGMSKKPQKPKHSSPGKKP--AGRKTRESQAAAREDNDPNRDEVPRAQ 408
           P   P   G  PQG +K    P    P   P   G K+R S++   +   P      + Q
Sbjct: 259 PPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ 316

Query: 409 LPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHA--PSGNQQPP 466
            P   PG P+    +G      P       P   +P    P G    R A  P G  Q P
Sbjct: 317 GPPPPPGKPQGPPPQGGNKPQGP-------PPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369

Query: 467 VHPPRPERQQQPPGAQGCPR 486
                   Q  PP A G P+
Sbjct: 370 PQQEGNNPQGPPPPAGGNPQ 389



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 102/423 (24%), Positives = 132/423 (31%), Gaps = 79/423 (18%)

Query: 81  EGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPS 140
           +G P  P   QG          ++P    PPP     P P+G    G+          P 
Sbjct: 48  QGPPSPPGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQG----GNKPQGPPPPGKPQ 99

Query: 141 GRDVLGHS-------PGKWQ-QASAGRLHLCGPGPVRAWKN---PERGSKSRWSLRVDPQ 189
           G    G         PGK Q     G     GP P         P+ G+K        PQ
Sbjct: 100 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK--------PQ 151

Query: 190 QPSAKGPTRLPTHDSDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQA 243
            P   G  + P    D+   SS  P  K       G  + +G    PG P+         
Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN- 210

Query: 244 SFHCKESYLPVPGRFLTSAPRG--LTPVAERPAVGELEDSPQKKMQSRAW----GKVEVR 297
               K    P PG+     P+G   +  A  P        PQ   Q +      GK +  
Sbjct: 211 ----KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 266

Query: 298 PSCSGAAAAGALPQGLSRRKMA-GGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356
           P   G    G  P G  +     GG KS    S     +G P  G      PP P   P 
Sbjct: 267 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP- 325

Query: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416
             G  PQG   KPQ P    P  KP G   +    +    + P + + P  Q   +  G 
Sbjct: 326 -QGPPPQG-GNKPQGP---PPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGP 380

Query: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476
           P           +  N + PQ P                   P+G  Q P  PP+  R  
Sbjct: 381 P---------PPAGGNPQQPQAP-------------------PAGQPQGPPRPPQGGRPS 412

Query: 477 QPP 479
           +PP
Sbjct: 413 RPP 415



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 25/135 (18%)

Query: 351 PATFPPFSGVRPQGMSKKPQKPKHSSP--GKKPAGRKTRESQAAAREDNDPNRDEVPRAQ 408
           P   PP  G +PQG    P KP+   P  G +P G      +         N+ + P   
Sbjct: 36  PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP- 94

Query: 409 LPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVH 468
                PG P+    +G+ S      R+P+ P         PG   P+   P G  QP   
Sbjct: 95  -----PGKPQGPPPQGDKS------RSPRSP---------PG--KPQGPPPQGGNQPQGP 132

Query: 469 PPRPERQQQPPGAQG 483
           PP P + Q PP   G
Sbjct: 133 PPPPGKPQGPPPQGG 147


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 120/496 (24%), Positives = 160/496 (32%), Gaps = 81/496 (16%)

Query: 13  GFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQ 72
           G D + G+K      SPG PG   +   +G  G    K E+G   P G        +I  
Sbjct: 290 GKDGDKGEKG-----SPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGI-------VIGT 337

Query: 73  GRVVLWGREGRPGTPVDDQGDVVDYSFY-LADEPAAI-VPPPSVQGHP-FPEGAAAEGSA 129
           G +   G  G PGTP   +G+     F  L  +P    +P P   G P FP     +G  
Sbjct: 338 GPLGEKGERGYPGTP-GPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDR 396

Query: 130 ENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQ 189
                +  GPSGRD L   PG              PGP      P +   +   +   P 
Sbjct: 397 GFPGTSLPGPSGRDGLPGPPG-------------SPGP------PGQPGYTNGIVECQPG 437

Query: 190 QPSAKGPTRLPTHD------SDSADESSDLPLMKVGICRN-------EGSQAKPGSPKKR 236
            P  +GP  +P          +   +     +  +   R         G    PG P  +
Sbjct: 438 PPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAK 497

Query: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAV----GELEDSPQKKMQSRAWG 292
            D         ++    VPG      P+G   +  +P      GE     + K      G
Sbjct: 498 GDRGLPG----RDGVAGVPG------PQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPG 547

Query: 293 KVEVRPSCSGAAAAGALP--QGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPE 350
               +P  +G A +       GL   K + G   L G      G GFP  G R    PP 
Sbjct: 548 -FPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFP--GSRGDTGPPG 604

Query: 351 PATFPPFSGVRPQGMSKKPQKP-KHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQL 409
           P  + P   +  +G +  P  P     PG K    K          +  P     P  Q 
Sbjct: 605 PPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQG 664

Query: 410 PTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHP 469
               PG P      GE         A   PG   P    P G+        G+  PP  P
Sbjct: 665 DRGFPGTPGRPGLPGEKG-------AVGQPGIGFPGPPGPKGV----DGLPGDMGPPGTP 713

Query: 470 PRPERQQQP--PGAQG 483
            RP     P  PG QG
Sbjct: 714 GRPGFNGLPGNPGVQG 729



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 117/472 (24%), Positives = 152/472 (32%), Gaps = 75/472 (15%)

Query: 29   PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88
            PG PG       +GVPG      E G   P G     +    E G   L G  G PG P 
Sbjct: 748  PGIPGTPGEKGSIGVPGV---PGEHGAIGPPGL----QGIRGEPGPPGLPGSVGSPGVP- 799

Query: 89   DDQGDVVDYSFYLADEPAAIVPPPSVQGHPF---PEGAAAEGSAENWADAEV-GPSGRDV 144
                            P     PP  QG P    P G   E     +   ++ GP G   
Sbjct: 800  -------------GIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG 846

Query: 145  LGHSPGKWQQASAGRLHLCGPGPVRAWKNPE-RGSKSRWSLRVDPQQPSAKGPT---RLP 200
                PG   Q+    L    PG   A   P   GSK    +   P QP + GP     LP
Sbjct: 847  AQGLPGITGQSGLPGL----PGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLP 902

Query: 201  THDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLT 260
                D     S  P    G+  ++G    PG P    D     S   ++      G+   
Sbjct: 903  GEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGS-MDKVDMGSMKGQKGDQGEKGQ--- 958

Query: 261  SAPRGLTPVAERPAVGE--LEDSPQKKMQSRAWGKVEVR--PSCSGAAAAGALPQGLSRR 316
                 + P+ E+ + G+      P K  Q+   G+   +  P  SG   A  LP      
Sbjct: 959  -----IGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLP------ 1007

Query: 317  KMAGGKKSLGGASQLALGRGFPAC-GERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHS 375
               G K S+G       G G P   GE+     P P   P   G +      K +K +  
Sbjct: 1008 ---GPKGSVG-------GMGLPGTPGEKGVPGIPGPQGSPGLPGDK----GAKGEKGQAG 1053

Query: 376  SPG-KKPAGRKTRESQAAAREDNDP-NRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNI 433
             PG   P  R  +  Q  A     P  + E     +P   PG P L    G         
Sbjct: 1054 PPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIP-GMPGSPGLKGSPGSVGYPG--- 1109

Query: 434  RAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485
             +P LPG            +P     +G    P  P  P  Q+  PG+ G P
Sbjct: 1110 -SPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTP-GPTGPAGQKGEPGSDGIP 1159



 Score = 37.4 bits (85), Expect = 0.033
 Identities = 45/156 (28%), Positives = 55/156 (35%), Gaps = 27/156 (17%)

Query: 354 FPPFSGVRPQGMSKKP-QKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTH 412
           FP   G  P+G    P QK     PG  P  + TR    A+    +P    +P    P  
Sbjct: 62  FPGMQG--PEGPQGPPGQKGDTGEPGL-PGTKGTRGPPGASGYPGNPGLPGIPGQDGPPG 118

Query: 413 RPGLPRLSVRRGEFSSSDP--------NIRAPQLPG----TSEPSAYSPGGL-------- 452
            PG+P  +  +GE     P        N   P LPG      E   + PG L        
Sbjct: 119 PPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFP 178

Query: 453 -VPRRHAPSG--NQQPPVHPPRPERQQQPPGAQGCP 485
            +P    P G    Q PV PP       PPG  G P
Sbjct: 179 GIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPP 214



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 118/512 (23%), Positives = 160/512 (31%), Gaps = 80/512 (15%)

Query: 29  PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTP- 87
           PG PG        G+PG    K E G   P G    +             G  G PG P 
Sbjct: 108 PGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFA-------------GNPGPPGLPG 154

Query: 88  -VDDQGDVVDY--SFYLADE------PAAIVPP--PSVQGHPFPEGAAAEGSAEN--WAD 134
              D G+++ +     L  E      P    PP  P +QG   P G              
Sbjct: 155 MKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPP 214

Query: 135 AEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVR-----AWKNPERGSKSRWSLRVDP- 188
            E G  G    G    K  Q  +G   + G   V+     A K  E+G K     +  P 
Sbjct: 215 GEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKG-EKGQKGEPGFQGMPG 273

Query: 189 ----QQPSAKGPTRLPTHDSDSADESS-DLP--------LMKVGICRNEGSQAKPGSPKK 235
                +P   GP   P  D D  ++ S   P        + + G    +G    PG P  
Sbjct: 274 VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGI 333

Query: 236 RADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVE 295
              T        +  Y   PG      P+G   +  +P    L        Q+ A G   
Sbjct: 334 VIGTGPLGE-KGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGL----PVPGQAGAPGFPG 388

Query: 296 VRPSCSGAAAAG-ALPQGLSRRKMAGGKKSLGGASQLALGRGFPAC--GERLSAAPPEPA 352
            R         G +LP    R  + G   S G   Q     G   C  G      PP   
Sbjct: 389 ERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIP 448

Query: 353 TFPPFSGVRPQGMSKKPQKPK----------HSSPGKK-PAGRKTRESQAAAREDND-PN 400
             P F G     + +K QK +             PG + P G      Q  A+ D   P 
Sbjct: 449 GQPGFIG----EIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPG 504

Query: 401 RDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPS 460
           RD V     P   PGL      +GE      ++R     G  +P      G+  R  +P 
Sbjct: 505 RDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKG--DPGFPGQPGMTGRAGSPG 562

Query: 461 GNQQPPVHPPRP-------ERQQQPPGAQGCP 485
            +  P +  P+        + ++ PPG  G P
Sbjct: 563 RDGHPGLPGPKGSPGSVGLKGERGPPGGVGFP 594



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 62/251 (24%), Positives = 79/251 (31%), Gaps = 47/251 (18%)

Query: 16   LEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRV 75
            L G K        PG+PG       +G+PG        G     G+   S     E+G  
Sbjct: 1062 LRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYP-GSPGLPGEKGDK 1120

Query: 76   VLWGREGRPGT-----------PVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAA 124
             L G +G PG            P    G   +         A     P + G  FP    
Sbjct: 1121 GLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPG 1180

Query: 125  AEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGP-----------GPVRAWKN 173
            A+G  +  +  EVG  G   L  SPG     S G     GP            P  A + 
Sbjct: 1181 AKG--DKGSKGEVGFPG---LAGSPG--IPGSKGEQGFMGPPGPQGQPGLPGSPGHATEG 1233

Query: 174  P--ERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPG 231
            P  +RG + +  L   P  P   GP  LP  D    D+             N G    PG
Sbjct: 1234 PKGDRGPQGQPGL---PGLPGPMGPPGLPGIDGVKGDKG------------NPGWPGAPG 1278

Query: 232  SPKKRADTSRQ 242
             P  + D   Q
Sbjct: 1279 VPGPKGDPGFQ 1289



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 27/77 (35%), Positives = 30/77 (38%), Gaps = 10/77 (12%)

Query: 29   PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88
            PG PG    G D G PG       +G T P GF           G   L G  G PGTP 
Sbjct: 1392 PGPPGIP--GFD-GAPGQKGEMGPAGPTGPRGFPGPP-------GPDGLPGSMGPPGTPS 1441

Query: 89   DDQGDVVDYSFYLADEP 105
             D G +V       D+P
Sbjct: 1442 VDHGFLVTRHSQTIDDP 1458


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 127/501 (25%), Positives = 166/501 (33%), Gaps = 104/501 (20%)

Query: 29   PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88
            PG PG      D GVPG        G     GF  E  S     G   L G  G PGTP 
Sbjct: 671  PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS----PGAQGLQGPRGLPGTPG 726

Query: 89   DD--QGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSG-RDVL 145
             D  +G         A  PA    PP  QG P  +G   E  A   A    GP G R  +
Sbjct: 727  TDGPKG---------ASGPAG---PPGAQGPPGLQGMPGERGAAGIA----GPKGDRGDV 770

Query: 146  GHSPGKWQQASAGRLHLCGP--GPVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203
            G    +      G   L GP   P  A  N E+G        V P  P+     R     
Sbjct: 771  GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG-------EVGPPGPAGSAGAR----- 818

Query: 204  SDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVP-GRFLTSA 262
                +     P    G     G+  +PG+  ++ +  ++      ++  P P G      
Sbjct: 819  GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG-----DAGAPGPQGPSGAPG 873

Query: 263  PRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGK 322
            P+G T V         +  P       A G+V    S       G  P G S +    G 
Sbjct: 874  PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG--PPGPSGK---DGP 928

Query: 323  KSLGGASQLALGRGFPACGERLSAAPP----EPATFPPFSGVR----PQGMSKK------ 368
            K   G S      G P  G +  A PP    EP    P SG      PQG++ +      
Sbjct: 929  KGARGDSGPPGRAGEP--GLQGPAGPPGEKGEPGDDGP-SGAEGPPGPQGLAGQRGIVGL 985

Query: 369  -PQKPKHSSPG-KKPAGRKTRESQAAARED----------------NDPNRDEVPRAQLP 410
              Q+ +   PG   P+G   ++    A  D                 +P R+  P A  P
Sbjct: 986  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 1045

Query: 411  THRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQ------- 463
              R G   +   RGE  +    + AP  PG   P +  P G       P+G Q       
Sbjct: 1046 PGRDGAAGVKGDRGETGA----VGAPGAPG--PPGSPGPAG-------PTGKQGDRGEAG 1092

Query: 464  -QPPVHPPRPERQQQPPGAQG 483
             Q P+ P  P   +   G QG
Sbjct: 1093 AQGPMGPSGPAGARGIQGPQG 1113



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 125/496 (25%), Positives = 158/496 (31%), Gaps = 113/496 (22%)

Query: 18  GGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTD---PEGFSFESESELIEQGR 74
           G +    +    G PG        G PG+   K E+G T    PEG       E    G 
Sbjct: 342 GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ-GPRGEPGTPGS 400

Query: 75  VVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPP--PSVQGHPFPEGAAAEGSAENW 132
               G  G PGT      D +  +   A  P     P  P  +G P P+GA         
Sbjct: 401 PGPAGASGNPGT------DGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP------ 448

Query: 133 ADAEVGPSGRDVLGHSPG----KWQQASAGRLHLCGP----GPV-RAWKNPERGSKSRWS 183
               +GP G+      PG    K +Q   G     GP    GP     K   RG      
Sbjct: 449 ----LGPKGQT---GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 501

Query: 184 LRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQA 243
               P +  A G    P  D  +  + +       G+   +G+   PG P +        
Sbjct: 502 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG------ 555

Query: 244 SFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGA 303
                     +PG       RGLT    RP     +  PQ K+        + RP   G 
Sbjct: 556 ----------LPGA------RGLTG---RPG----DAGPQGKVGPSGAPGEDGRPGPPGP 592

Query: 304 AAA----GAL----PQGLSRRKMAGGKKSLGGASQLALGRGFPAC-GERLSAAPPEPATF 354
             A    G +    P+G +      G+K L GA  L   RG P   GE  +A PP PA  
Sbjct: 593 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL---RGLPGKDGETGAAGPPGPAGP 649

Query: 355 PPFSGVR----PQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLP 410
               G +    P G    P  P     G KP             +   P     P    P
Sbjct: 650 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG------------DQGVPGEAGAPGLVGP 697

Query: 411 THRPGLPRLSVRRGEFSSSDPNIRAPQ-LPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHP 469
               G P     RG  S     ++ P+ LPGT  P    P G        SG       P
Sbjct: 698 RGERGFPG---ERG--SPGAQGLQGPRGLPGT--PGTDGPKGA-------SG-------P 736

Query: 470 PRPERQQQPPGAQGCP 485
             P   Q PPG QG P
Sbjct: 737 AGPPGAQGPPGLQGMP 752



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 126/504 (25%), Positives = 158/504 (31%), Gaps = 100/504 (19%)

Query: 13  GFDLEGGK--KAGSR-----------TASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPE 59
           G D E GK  KAG R             +PG PG   H    G PG    K E+G    +
Sbjct: 252 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR---GYPGLDGAKGEAGAPGVK 308

Query: 60  GFSFE-----SESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSV 114
           G S       S   +  +G     GR G  G       D          +P    PP  V
Sbjct: 309 GESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND---------GQPGPAGPPGPV 359

Query: 115 ---QGHPFPEGAAAEGSAENWADAEVGPSG-RDVLGHSPGKWQQASAGRLHLCGPGPVRA 170
               G  FP    A+G        E GP+G R   G    + +  + G      PGP  A
Sbjct: 360 GPAGGPGFPGAPGAKG--------EAGPTGARGPEGAQGPRGEPGTPG-----SPGPAGA 406

Query: 171 WKNP-------ERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRN 223
             NP        +GS     +   P  P  +GP   P     +          + GI   
Sbjct: 407 SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP---PGPQGATGPLGPKGQTGEPGIAGF 463

Query: 224 EGSQAKPGSPKKRADTSR--QASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDS 281
           +G Q   G P           A    K      PG      P G  P  ER A G     
Sbjct: 464 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGV---GPIG--PPGERGAPG----- 513

Query: 282 PQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACG 341
                 +R +   +      GA      P GL+  K A G     G   L   RG     
Sbjct: 514 ------NRGFPGQDGLAGPKGAPGERG-PSGLAGPKGANGDPGRPGEPGLPGARGLTG-- 564

Query: 342 ERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNR 401
            R   A P+    P  SG    G   +P  P       +P        + A  E      
Sbjct: 565 -RPGDAGPQGKVGP--SGA--PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 619

Query: 402 DEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSG 461
             +P A      PGL  L  + GE  ++ P       PG + P+        P    PSG
Sbjct: 620 KGLPGA------PGLRGLPGKDGETGAAGP-------PGPAGPAGERGEQGAP---GPSG 663

Query: 462 NQQPPVHPPRPERQQQPPGAQGCP 485
            Q  P  PP P  +   PG QG P
Sbjct: 664 FQGLP-GPPGPPGEGGKPGDQGVP 686



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 116/500 (23%), Positives = 147/500 (29%), Gaps = 98/500 (19%)

Query: 17   EGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDG---------KSESGFTDPEGFSFESES 67
            +GG+        PG  GA+    ++G PG             + E+G   P GF+    +
Sbjct: 782  DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 841

Query: 68   E-----LIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEG 122
            +       EQG     G  G PG P    G            P  +  P   +G   P G
Sbjct: 842  DGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQG------PTGVTGPKGARGAQGPPG 894

Query: 123  AAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRW 182
            A     A       VGP G +     PG       G     GP   R    P  G     
Sbjct: 895  ATGFPGAA----GRVGPPGSNGNPGPPG-----PPGPSGKDGPKGARGDSGPP-GRAGEP 944

Query: 183  SLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMK------VGICRNEGSQAKPGSPKKR 236
             L+     P  KG    P  D  S  E    P         VG+    G +  PG P   
Sbjct: 945  GLQGPAGPPGEKGE---PGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 1001

Query: 237  ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296
             +  +Q +        P PG      P GLT  A  P                       
Sbjct: 1002 GEPGKQGAPGASGDRGP-PG---PVGPPGLTGPAGEPG---------------------- 1035

Query: 297  RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356
            R    GA        G   R  A G K   G +      G P          P PA    
Sbjct: 1036 REGSPGA-------DGPPGRDGAAGVKGDRGETGAVGAPGAPG-----PPGSPGPAGPTG 1083

Query: 357  FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHR--- 413
              G R +  ++ P  P        PAG +  +     R D     +   R  L  HR   
Sbjct: 1084 KQGDRGEAGAQGPMGP------SGPAGARGIQGPQGPRGDKGEAGEPGERG-LKGHRGFT 1136

Query: 414  -----PGLPRLSVRRGEFSSSDPN-IRAPQLPGTSEPSAYSPGGLVPRRHAPSG--NQQP 465
                 PG P  S  +G    + P+  R P  PG   PS       +P    P G   +  
Sbjct: 1137 GLQGLPGPPGPSGDQGASGPAGPSGPRGP--PGPVGPSGKDGANGIPGPIGPPGPRGRSG 1194

Query: 466  PVHPPRPERQQQPPGAQGCP 485
               P  P     PPG  G P
Sbjct: 1195 ETGPAGPPGNPGPPGPPGPP 1214



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 37/143 (25%), Positives = 52/143 (36%), Gaps = 22/143 (15%)

Query: 16   LEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRV 75
            ++G +       +PGAPG        G  G    + E+G   P G S  + +  I QG  
Sbjct: 1054 VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI-QGPQ 1112

Query: 76   VLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWA-- 133
               G +G  G P  ++G      F              +QG P P G + +  A   A  
Sbjct: 1113 GPRGDKGEAGEP-GERGLKGHRGF------------TGLQGLPGPPGPSGDQGASGPAGP 1159

Query: 134  ------DAEVGPSGRDVLGHSPG 150
                     VGPSG+D     PG
Sbjct: 1160 SGPRGPPGPVGPSGKDGANGIPG 1182


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 127/501 (25%), Positives = 166/501 (33%), Gaps = 104/501 (20%)

Query: 29   PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88
            PG PG      D GVPG        G     GF  E  S     G   L G  G PGTP 
Sbjct: 602  PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS----PGAQGLQGPRGLPGTPG 657

Query: 89   DD--QGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSG-RDVL 145
             D  +G         A  PA    PP  QG P  +G   E  A   A    GP G R  +
Sbjct: 658  TDGPKG---------ASGPAG---PPGAQGPPGLQGMPGERGAAGIA----GPKGDRGDV 701

Query: 146  GHSPGKWQQASAGRLHLCGP--GPVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203
            G    +      G   L GP   P  A  N E+G        V P  P+     R     
Sbjct: 702  GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG-------EVGPPGPAGSAGAR----- 749

Query: 204  SDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVP-GRFLTSA 262
                +     P    G     G+  +PG+  ++ +  ++      ++  P P G      
Sbjct: 750  GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG-----DAGAPGPQGPSGAPG 804

Query: 263  PRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGK 322
            P+G T V         +  P       A G+V    S       G  P G S +    G 
Sbjct: 805  PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG--PPGPSGK---DGP 859

Query: 323  KSLGGASQLALGRGFPACGERLSAAPP----EPATFPPFSGVR----PQGMSKK------ 368
            K   G S      G P  G +  A PP    EP    P SG      PQG++ +      
Sbjct: 860  KGARGDSGPPGRAGEP--GLQGPAGPPGEKGEPGDDGP-SGAEGPPGPQGLAGQRGIVGL 916

Query: 369  -PQKPKHSSPG-KKPAGRKTRESQAAARED----------------NDPNRDEVPRAQLP 410
              Q+ +   PG   P+G   ++    A  D                 +P R+  P A  P
Sbjct: 917  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 976

Query: 411  THRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQ------- 463
              R G   +   RGE  +    + AP  PG   P +  P G       P+G Q       
Sbjct: 977  PGRDGAAGVKGDRGETGA----VGAPGAPG--PPGSPGPAG-------PTGKQGDRGEAG 1023

Query: 464  -QPPVHPPRPERQQQPPGAQG 483
             Q P+ P  P   +   G QG
Sbjct: 1024 AQGPMGPSGPAGARGIQGPQG 1044



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 125/496 (25%), Positives = 158/496 (31%), Gaps = 113/496 (22%)

Query: 18  GGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTD---PEGFSFESESELIEQGR 74
           G +    +    G PG        G PG+   K E+G T    PEG       E    G 
Sbjct: 273 GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ-GPRGEPGTPGS 331

Query: 75  VVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPP--PSVQGHPFPEGAAAEGSAENW 132
               G  G PGT      D +  +   A  P     P  P  +G P P+GA         
Sbjct: 332 PGPAGASGNPGT------DGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP------ 379

Query: 133 ADAEVGPSGRDVLGHSPG----KWQQASAGRLHLCGP----GPV-RAWKNPERGSKSRWS 183
               +GP G+      PG    K +Q   G     GP    GP     K   RG      
Sbjct: 380 ----LGPKGQT---GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 432

Query: 184 LRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQA 243
               P +  A G    P  D  +  + +       G+   +G+   PG P +        
Sbjct: 433 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG------ 486

Query: 244 SFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGA 303
                     +PG       RGLT    RP     +  PQ K+        + RP   G 
Sbjct: 487 ----------LPGA------RGLTG---RPG----DAGPQGKVGPSGAPGEDGRPGPPGP 523

Query: 304 AAA----GAL----PQGLSRRKMAGGKKSLGGASQLALGRGFPAC-GERLSAAPPEPATF 354
             A    G +    P+G +      G+K L GA  L   RG P   GE  +A PP PA  
Sbjct: 524 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL---RGLPGKDGETGAAGPPGPAGP 580

Query: 355 PPFSGVR----PQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLP 410
               G +    P G    P  P     G KP             +   P     P    P
Sbjct: 581 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG------------DQGVPGEAGAPGLVGP 628

Query: 411 THRPGLPRLSVRRGEFSSSDPNIRAPQ-LPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHP 469
               G P     RG  S     ++ P+ LPGT  P    P G        SG       P
Sbjct: 629 RGERGFPG---ERG--SPGAQGLQGPRGLPGT--PGTDGPKGA-------SG-------P 667

Query: 470 PRPERQQQPPGAQGCP 485
             P   Q PPG QG P
Sbjct: 668 AGPPGAQGPPGLQGMP 683



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 126/504 (25%), Positives = 158/504 (31%), Gaps = 100/504 (19%)

Query: 13  GFDLEGGK--KAGSR-----------TASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPE 59
           G D E GK  KAG R             +PG PG   H    G PG    K E+G    +
Sbjct: 183 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR---GYPGLDGAKGEAGAPGVK 239

Query: 60  GFSFE-----SESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSV 114
           G S       S   +  +G     GR G  G       D          +P    PP  V
Sbjct: 240 GESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND---------GQPGPAGPPGPV 290

Query: 115 ---QGHPFPEGAAAEGSAENWADAEVGPSG-RDVLGHSPGKWQQASAGRLHLCGPGPVRA 170
               G  FP    A+G        E GP+G R   G    + +  + G      PGP  A
Sbjct: 291 GPAGGPGFPGAPGAKG--------EAGPTGARGPEGAQGPRGEPGTPG-----SPGPAGA 337

Query: 171 WKNP-------ERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRN 223
             NP        +GS     +   P  P  +GP   P     +          + GI   
Sbjct: 338 SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP---PGPQGATGPLGPKGQTGEPGIAGF 394

Query: 224 EGSQAKPGSPKKRADTSR--QASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDS 281
           +G Q   G P           A    K      PG      P G  P  ER A G     
Sbjct: 395 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGV---GPIG--PPGERGAPG----- 444

Query: 282 PQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACG 341
                 +R +   +      GA      P GL+  K A G     G   L   RG     
Sbjct: 445 ------NRGFPGQDGLAGPKGAPGERG-PSGLAGPKGANGDPGRPGEPGLPGARGLTG-- 495

Query: 342 ERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNR 401
            R   A P+    P  SG    G   +P  P       +P        + A  E      
Sbjct: 496 -RPGDAGPQGKVGP--SGA--PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 550

Query: 402 DEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSG 461
             +P A      PGL  L  + GE  ++ P       PG + P+        P    PSG
Sbjct: 551 KGLPGA------PGLRGLPGKDGETGAAGP-------PGPAGPAGERGEQGAP---GPSG 594

Query: 462 NQQPPVHPPRPERQQQPPGAQGCP 485
            Q  P  PP P  +   PG QG P
Sbjct: 595 FQGLP-GPPGPPGEGGKPGDQGVP 617



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 116/500 (23%), Positives = 147/500 (29%), Gaps = 98/500 (19%)

Query: 17   EGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDG---------KSESGFTDPEGFSFESES 67
            +GG+        PG  GA+    ++G PG             + E+G   P GF+    +
Sbjct: 713  DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 772

Query: 68   E-----LIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEG 122
            +       EQG     G  G PG P    G            P  +  P   +G   P G
Sbjct: 773  DGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQG------PTGVTGPKGARGAQGPPG 825

Query: 123  AAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRW 182
            A     A       VGP G +     PG       G     GP   R    P  G     
Sbjct: 826  ATGFPGAA----GRVGPPGSNGNPGPPG-----PPGPSGKDGPKGARGDSGPP-GRAGEP 875

Query: 183  SLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMK------VGICRNEGSQAKPGSPKKR 236
             L+     P  KG    P  D  S  E    P         VG+    G +  PG P   
Sbjct: 876  GLQGPAGPPGEKGE---PGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932

Query: 237  ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296
             +  +Q +        P PG      P GLT  A  P                       
Sbjct: 933  GEPGKQGAPGASGDRGP-PG---PVGPPGLTGPAGEPG---------------------- 966

Query: 297  RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356
            R    GA        G   R  A G K   G +      G P          P PA    
Sbjct: 967  REGSPGA-------DGPPGRDGAAGVKGDRGETGAVGAPGAPG-----PPGSPGPAGPTG 1014

Query: 357  FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHR--- 413
              G R +  ++ P  P        PAG +  +     R D     +   R  L  HR   
Sbjct: 1015 KQGDRGEAGAQGPMGP------SGPAGARGIQGPQGPRGDKGEAGEPGERG-LKGHRGFT 1067

Query: 414  -----PGLPRLSVRRGEFSSSDPN-IRAPQLPGTSEPSAYSPGGLVPRRHAPSG--NQQP 465
                 PG P  S  +G    + P+  R P  PG   PS       +P    P G   +  
Sbjct: 1068 GLQGLPGPPGPSGDQGASGPAGPSGPRGP--PGPVGPSGKDGANGIPGPIGPPGPRGRSG 1125

Query: 466  PVHPPRPERQQQPPGAQGCP 485
               P  P     PPG  G P
Sbjct: 1126 ETGPAGPPGNPGPPGPPGPP 1145



 Score = 30.0 bits (66), Expect = 5.3
 Identities = 37/143 (25%), Positives = 52/143 (36%), Gaps = 22/143 (15%)

Query: 16   LEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRV 75
            ++G +       +PGAPG        G  G    + E+G   P G S  + +  I QG  
Sbjct: 985  VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI-QGPQ 1043

Query: 76   VLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWA-- 133
               G +G  G P  ++G      F              +QG P P G + +  A   A  
Sbjct: 1044 GPRGDKGEAGEP-GERGLKGHRGF------------TGLQGLPGPPGPSGDQGASGPAGP 1090

Query: 134  ------DAEVGPSGRDVLGHSPG 150
                     VGPSG+D     PG
Sbjct: 1091 SGPRGPPGPVGPSGKDGANGIPG 1113


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 121/486 (24%), Positives = 165/486 (33%), Gaps = 93/486 (19%)

Query: 17   EGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVV 76
            +G   +  R  +PG PGA       G+PG      E G   P+G    +  ++I      
Sbjct: 1304 DGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKG-EPGAPGQVIGGEGPG 1362

Query: 77   LWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAE 136
            L GR+G PG P    G            P   +  P  +G P   G A +G  +     E
Sbjct: 1363 LPGRKGDPG-PSGPPG------------PRGPLGDPGPRGPPGLPGTAMKG--DKGDRGE 1407

Query: 137  VGPSGRDVLGHSPGKWQQASAGRLHLCGP-GPV-RAWKNPERGSKSRWS--LRVDPQQPS 192
             GP G    G +PG  +    G     GP GPV    K  E+G     +  L   P  P 
Sbjct: 1408 RGPPGPGEGGIAPG--EPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPG 1465

Query: 193  AKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYL 252
             +GP   P       D     PL + G    +G +  PG                     
Sbjct: 1466 EQGPRGPPGAIGPKGDRGFPGPLGEAG---EKGERGPPG--------------------- 1501

Query: 253  PVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKV--EVRPSCSGAAAAGALP 310
                    +  RGL  VA RP     E  P    +    G+      P+  G A AG  P
Sbjct: 1502 -------PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAG--P 1552

Query: 311  QGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQ 370
            +G    K   G     GA+ +   RG P     +    P P   P   G  P G++ +  
Sbjct: 1553 KG---EKGDVGPAGPRGATGVQGERGPPGL---VLPGDPGPKGDPGDRG--PIGLTGRAG 1604

Query: 371  KPKHSS-PGKK----------PAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRL 419
             P  S  PG+K          P G + R+ +   + D  P  D           PGLP  
Sbjct: 1605 PPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGD-----------PGLPGK 1653

Query: 420  SVRRGEFSSSDPNIRAP--QLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPER-QQ 476
            +  RG      P +R P  +     +P      G  P    P G++  P  P  P R   
Sbjct: 1654 AGERG--LRGAPGVRGPVGEKGDQGDPGEDGRNG-SPGSSGPKGDRGEPGPPGPPGRLVD 1710

Query: 477  QPPGAQ 482
              PGA+
Sbjct: 1711 TGPGAR 1716



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 120/486 (24%), Positives = 148/486 (30%), Gaps = 97/486 (19%)

Query: 29   PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88
            PG PG        G+PG   G  E+G     G   E + E  EQGR    G  G PG P 
Sbjct: 2036 PGKPGIP------GLPGRAGGVGEAGRPGERGERGE-KGERGEQGRDGPPGLPGTPGPP- 2087

Query: 89   DDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSG-RDVLGH 147
               G  V       DEP      P + G   P G       E  ++ + GP G R V G 
Sbjct: 2088 GPPGPKVS-----VDEPG-----PGLSGEQGPPGLKG-AKGEPGSNGDQGPKGDRGVPGI 2136

Query: 148  SPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSA 207
               + +           PGP     NP  G      +     +P  +GP   P       
Sbjct: 2137 KGDRGE-----------PGPRGQDGNP--GLPGERGMAGPEGKPGLQGPRGPPGPVGGHG 2183

Query: 208  DESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLT 267
            D     P    G+    G Q   G   +  +T               PGR LT  P G  
Sbjct: 2184 DPG---PPGAPGLAGPAGPQGPSGLKGEPGETGP-------------PGRGLTG-PTGAV 2226

Query: 268  PVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGG 327
             +   P    L   PQ              P   G       P G   R  A GK    G
Sbjct: 2227 GLPGPPGPSGLV-GPQGS------------PGLPGQVGETGKP-GAPGRDGASGKDGDRG 2272

Query: 328  ASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKH------SSPGKK- 380
            +  +    G P  G       P P   P  + V   G   +   P          PG K 
Sbjct: 2273 SPGVPGSPGLP--GPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKG 2330

Query: 381  ----PAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRA- 435
                P  R  +     A E  DP  D    A  P    G P + V         P ++  
Sbjct: 2331 DRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGD 2390

Query: 436  ---PQLPGTSEPSAYSPGGLVPR----RHAPSGNQ-----------QPPVHPPRPERQQQ 477
               P LPG      + PG   PR    +  PSG +             P+ PP P     
Sbjct: 2391 LGLPGLPGAPGVVGF-PGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVG 2449

Query: 478  PPGAQG 483
            PPGA G
Sbjct: 2450 PPGASG 2455



 Score = 37.4 bits (85), Expect = 0.033
 Identities = 113/494 (22%), Positives = 142/494 (28%), Gaps = 92/494 (18%)

Query: 15   DLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGR 74
            D   G +        G  G      D G+PG+   +   GF  P                
Sbjct: 1710 DTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPP--------------- 1754

Query: 75   VVLWGREGRPGT--PVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEG--AAAEGSAE 130
                G +G PG   P  ++GD                 PP + G    +G   AA  S  
Sbjct: 1755 ----GPQGDPGVRGPAGEKGD---------------RGPPGLDGRSGLDGKPGAAGPSGP 1795

Query: 131  NWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPG--PVRAWKNPERGSKSRWSLRVDP 188
            N A  + G  GRD L   PG       G   L GP   P    K  E G         +P
Sbjct: 1796 NGAAGKAGDPGRDGL---PG-----LRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEP 1847

Query: 189  QQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCK 248
              P   G          S  E  D P  + G     G Q  PG P               
Sbjct: 1848 GDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLP--------------- 1892

Query: 249  ESYLPVPGRFLTSAPRGLTPVAERPAVGELEDS--PQKKMQSRAWGKVEVRPSCSGAAAA 306
               +  PG+     P G  P  +R   G   +   P ++      G V   P+       
Sbjct: 1893 -GPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSV---PNVDRLLET 1948

Query: 307  GALPQGLSRRKMAGGKKSLGGASQLALGRGFPA--CGERLSAAPPEPATFPPFSGVRPQG 364
              +     R  +    +S G    +   R  P    GE+       P  FP   G++   
Sbjct: 1949 AGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDR 2008

Query: 365  MSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRG 424
                PQ P    PG     R        A E   P    +P         G P     RG
Sbjct: 2009 GDPGPQGP----PGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERG 2064

Query: 425  EFSSSDPNIR--APQLPGTSEPSAYSPGGLVPRRHAP------SGNQQPP-----VHPPR 471
            E        R   P LPGT  P    PG   P+          SG Q PP        P 
Sbjct: 2065 EKGERGEQGRDGPPGLPGTPGP----PGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPG 2120

Query: 472  PERQQQPPGAQGCP 485
                Q P G +G P
Sbjct: 2121 SNGDQGPKGDRGVP 2134



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 60/242 (24%), Positives = 89/242 (36%), Gaps = 68/242 (28%)

Query: 16   LEGGKKAGSRTASPGAPGAHSHGLDL---GVPGSGDGKSESGFTDPEGFSFESESELIEQ 72
            L+G K        PG PG   H  ++   GVPG      + G   P+G            
Sbjct: 2636 LDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDR---------- 2685

Query: 73   GRVVLWGREGRPGTPVDDQGD--------VVDYSFYLADEPAAIVP-PPSVQGHPFPEGA 123
                  G +G+PG P  DQG+        +  +     ++ +A  P PP   G   PEG 
Sbjct: 2686 ------GFDGQPG-PKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGL 2738

Query: 124  AAEGSAENWADAEVGPSGRDVLGHSPG----KWQQASAGRLHLCGPGPVRAWKNPERGSK 179
              +         E GP G  V+G +PG      ++   GR     PGP        RG K
Sbjct: 2739 QGQ-------KGERGPPGERVVG-APGVPGAPGERGEQGR-----PGPA-----GPRGEK 2780

Query: 180  SRWSLRVDP------QQPS----------AKGPTRLPTHDSDSA-DESSDLPLMKVGICR 222
               +L  D       Q+ S          A G   LP++ +D+A  +   +P+++V    
Sbjct: 2781 GEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYAADTAGSQLHAVPVLRVSHAE 2840

Query: 223  NE 224
             E
Sbjct: 2841 EE 2842



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 121/491 (24%), Positives = 150/491 (30%), Gaps = 93/491 (18%)

Query: 13   GFDLEGGKKAGSRTASPGAP-GAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIE 71
            G D   G       A P  P GA     D G  G    + E G   P G       +  E
Sbjct: 1776 GLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP-GLPGKPGE 1834

Query: 72   QGRVVLWGREGRPGTPVDD-----QGDVVDYSFYLADEP------AAIVPPPSVQGHPFP 120
             G+  L G+ G PG P +D     +GD         D P        I+ P    G P P
Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP 1894

Query: 121  EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS 180
             G   +G          GP G    G +  K +Q   G   L G          E GS  
Sbjct: 1895 VGPPGQGFP--GVPGGTGPKGD--RGETGSKGEQGLPGERGLRG----------EPGSVP 1940

Query: 181  RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS 240
                 ++     A     +     +S+     +P  + G   + G Q  PG         
Sbjct: 1941 NVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPG--------- 1991

Query: 241  RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC 300
                   KE  +  PG       RG       P +   E  P               P  
Sbjct: 1992 -------KEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGP---------------PGP 2029

Query: 301  SGAAAAGALP--QGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFS 358
            SG A     P   GL  R  AGG    G   +    RG    GER       P   P   
Sbjct: 2030 SGLAGEPGKPGIPGLPGR--AGGVGEAGRPGERG-ERG--EKGERGEQGRDGPPGLPGTP 2084

Query: 359  GVRPQGMSKKPQKPKHS--SPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416
            G  P G    P  PK S   PG   +G +       A+ +   N D+ P+        G+
Sbjct: 2085 G--PPG----PPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGD-----RGV 2133

Query: 417  PRLSVRRGEFS--SSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPER 474
            P +   RGE      D N   P LPG  E     P G  P    P G       PP P  
Sbjct: 2134 PGIKGDRGEPGPRGQDGN---PGLPG--ERGMAGPEG-KPGLQGPRG-------PPGPVG 2180

Query: 475  QQQPPGAQGCP 485
                PG  G P
Sbjct: 2181 GHGDPGPPGAP 2191



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 67/271 (24%), Positives = 81/271 (29%), Gaps = 79/271 (29%)

Query: 11   GAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELI 70
            G   DL G   A      PG  G        G PG      + G   P+GF  +      
Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDP----- 2371

Query: 71   EQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAE 130
                V + G  G PG P   +GD+      L   P A    P V G P   G   E    
Sbjct: 2372 ---GVGVPGSPGPPGPP-GVKGDL-----GLPGLPGA----PGVVGFPGQTGPRGE---- 2414

Query: 131  NWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQQ 190
                 + GPSG   L   PG+             PGP+                   P  
Sbjct: 2415 ---MGQPGPSGERGLAGPPGREGI----------PGPLG-----------------PPGP 2444

Query: 191  PSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKES 250
            P + GP        D  D    LP          G + + G P  R +  R         
Sbjct: 2445 PGSVGPPGASGLKGDKGDPGVGLP----------GPRGERGEPGIRGEDGR--------- 2485

Query: 251  YLPVPGRFLTSAPRGLT-PVAERPAVGELED 280
                PG+     PRGLT P   R   GE  D
Sbjct: 2486 ----PGQ---EGPRGLTGPPGSRGERGEKGD 2509



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 112/455 (24%), Positives = 139/455 (30%), Gaps = 89/455 (19%)

Query: 28   SPGAPGAHSHGLDLGVPGSGDGKSESGF---TDPEGFSFESESELIEQGRVVLWGREGRP 84
            SPG PG      DLG+PG        GF   T P G          E+G     GREG P
Sbjct: 2378 SPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRG-EMGQPGPSGERGLAGPPGREGIP 2436

Query: 85   GTPVDDQGDVVDYSFYLADEPAAIVPP-----------PSVQGHPFPEGAAAEGSAENWA 133
            G P+   G            P ++ PP           P V G P P G   E       
Sbjct: 2437 G-PLGPPG-----------PPGSVGPPGASGLKGDKGDPGV-GLPGPRGERGEPGIRG-E 2482

Query: 134  DAEVGPSGRDVLGHSPG-------KWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRV 186
            D   G  G   L   PG       K    SAG     G   V       RG+K     R 
Sbjct: 2483 DGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERG 2542

Query: 187  DPQQPSAKGPTRLPTHDSDSADE-------SSDLPLMK-----------VGICRNEGSQA 228
                   KGP        D   +       S+ LP ++            GI  + GS  
Sbjct: 2543 PRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG 2602

Query: 229  KPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQS 288
            K G P  R +                 G      PRGL    ER   G      +K  + 
Sbjct: 2603 KDGVPGIRGE----------------KGDVGFMGPRGLK--GERGVKGACGLDGEKGDKG 2644

Query: 289  RAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPA-------CG 341
             A      RP  +G       P G+  +  A GK+ L G       RGF          G
Sbjct: 2645 EA--GPPGRPGLAGHKGEMGEP-GVPGQSGAPGKEGLIGPKG---DRGFDGQPGPKGDQG 2698

Query: 342  ERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPA--GRKTRESQAAAREDNDP 399
            E+     P    FP  SG    G +  P  P    P       G+K        R    P
Sbjct: 2699 EKGERGTPGIGGFPGPSG--NDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAP 2756

Query: 400  NRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIR 434
                 P  +    RPG       +GE + ++ +IR
Sbjct: 2757 GVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIR 2791



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 52/212 (24%), Positives = 66/212 (31%), Gaps = 34/212 (16%)

Query: 25   RTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRP 84
            +  +PG  GA     D G PG        G   P+G    + +    Q  V L G +G  
Sbjct: 2255 KPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP--GQAVVGLPGAKGEK 2312

Query: 85   GTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGS-----AENWADAEVGP 139
            G P    GD+V        EP A       +G P P G   E        +   D + G 
Sbjct: 2313 GAPGGLAGDLV-------GEPGA----KGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGA 2361

Query: 140  SGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRL 199
             G       PG     S G      PGP         G K    L   P  P A G    
Sbjct: 2362 PGPKGFKGDPGVGVPGSPG-----PPGP--------PGVKGDLGL---PGLPGAPGVVGF 2405

Query: 200  PTHDSDSADESSDLPLMKVGICRNEGSQAKPG 231
            P       +     P  + G+    G +  PG
Sbjct: 2406 PGQTGPRGEMGQPGPSGERGLAGPPGREGIPG 2437


>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
           sapiens]
          Length = 735

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 64/239 (26%), Positives = 85/239 (35%), Gaps = 25/239 (10%)

Query: 270 AERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGL---SRRKMAGGKKSLG 326
           A+RP     E  PQ    S+A  +    P  S + A GA  Q L   SRR + GG K   
Sbjct: 33  AQRPEPSPPEPEPQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSSRRWVLGGAKP-- 90

Query: 327 GASQLALGRGFPACGERLSAA---------PPEPATFPPFSGVRPQGMSKKPQKPKHSSP 377
            A   +LG G P  GE              P  PA  PP  G +P     +   P+ ++P
Sbjct: 91  -AEDTSLGPGVPGTGEPAGEIWYNPIPEEDPRPPAPEPP--GPQPGSAESEGLAPQGAAP 147

Query: 378 GKKPAGRKTRESQAAAREDNDPNRDEVP--RAQLPTHRPGLPRLSVRRGEFSSSDPNIRA 435
              P      +S   AR  +   + ++P  R +L    P   R   R     S       
Sbjct: 148 ASPPTKASRTKSPGPARRLSIKMK-KLPELRRRLSLRGPRAGRERERAAPAGSVISRYHL 206

Query: 436 PQLPGTSEPSAYSPGGLVPRRHAPSGNQQP--PVHPPRP---ERQQQPPGAQGCPRCIW 489
               G   P+A   G   PR    S    P  P  PP P      +  P A+  P  +W
Sbjct: 207 DSSVGGPGPAAGPGGTRSPRAGYLSDGDSPERPAGPPSPTSFRPYEVGPAARAPPAALW 265


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 64/302 (21%), Positives = 109/302 (36%), Gaps = 27/302 (8%)

Query: 173  NPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGS 232
            +P+   K+  S       P      R P+ +  S+  S   P MK G+ R    +++ GS
Sbjct: 1387 SPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASS---PEMKDGLPRTPSRRSRSGS 1443

Query: 233  PKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWG 292
                 D S   S H      P       +  RG +     P    L  +P+ + +S +  
Sbjct: 1444 SPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSP 1503

Query: 293  KVE---VRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPP 349
            ++    + P    + +  ++ Q    R   G +   G + +L +         + SA+P 
Sbjct: 1504 ELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV---------KPSASPQ 1554

Query: 350  EPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQL 409
            E +     S    +  ++ P + +  S        K+R S   +R  + P   + PRA  
Sbjct: 1555 ERSESD--SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA- 1611

Query: 410  PTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHP 469
                   PR   + G  SS +P   AP+       S  S  G  P     S  +  P HP
Sbjct: 1612 -------PR--AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662

Query: 470  PR 471
            P+
Sbjct: 1663 PK 1664



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 80/344 (23%), Positives = 122/344 (35%), Gaps = 39/344 (11%)

Query: 120  PEGAAAEGSAENWADAEVGPSGRDVLGHSPGKW---QQASAGRLHL-CGPGPVRAWKNPE 175
            P   +  GS+    D    PS   + G SPG     +  S GR      P P    + P 
Sbjct: 1435 PSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR 1494

Query: 176  RGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSD---LPLMKVGICRNEGS----QA 228
              S+S       P  P        P  +   ++ S D   +    +G     GS      
Sbjct: 1495 PRSRS-------PSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547

Query: 229  KP-GSPKKRADTSRQASFHCKESYLPVPGRFLT-SAPRGLTPVAERPAVGELEDSPQKKM 286
            KP  SP++R+++        K +  P+  R  + S+P   +     P       SP+ K 
Sbjct: 1548 KPSASPQERSESDSSPDSKAK-TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606

Query: 287  QSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSA 346
            + RA  + +     S    A A P+ L RR  +G             GRG    G   + 
Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPA-PRALPRRSRSGSSSK---------GRGPSPEGSSSTE 1656

Query: 347  APPEPATFPPFSGVRPQGMSKKPQ-KPKHSSPGKKPAGRK----TRESQAAAREDNDPNR 401
            + PE    PP S    +G    P+ K K  +P ++ + R     TR+++ + R  +  + 
Sbjct: 1657 SSPE---HPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSS 1713

Query: 402  DEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPS 445
             E      P HR      S    E S S    R+   P T   S
Sbjct: 1714 PETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS 1757



 Score = 36.6 bits (83), Expect = 0.056
 Identities = 70/311 (22%), Positives = 105/311 (33%), Gaps = 39/311 (12%)

Query: 187 DPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFH 246
           + +QP+ + P         S+  S      K    ++ G +++  SP++    S +   H
Sbjct: 159 EAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKH 218

Query: 247 CKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAA-A 305
             ES             R  TP ++R +    +D  +K+ +S        R   S +A +
Sbjct: 219 RSES------ESKKRKHRSPTPKSKRKS----KDKKRKRSRSTTPAPKSRRAHRSTSADS 268

Query: 306 AGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPP--EPATFPPFSGVRPQ 363
           A +     SR + A  K      + LA     PA G R     P  EP T        P+
Sbjct: 269 ASSSDTSRSRSRSAAAKTH---TTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPE 325

Query: 364 GMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRD------------------EVP 405
             +K+P  P       K     TR S +  R    P                       P
Sbjct: 326 TATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTP 385

Query: 406 RAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQP 465
            +Q P + P     S  R       P  + PQ   +SE S  SP      RHA S  + P
Sbjct: 386 LSQEPVNPPS--EASPTRDRSPPKSPE-KLPQ-SSSSESSPPSPQPTKVSRHASSSPESP 441

Query: 466 -PVHPPRPERQ 475
            P   P   R+
Sbjct: 442 KPAPAPGSHRE 452



 Score = 36.2 bits (82), Expect = 0.073
 Identities = 70/326 (21%), Positives = 119/326 (36%), Gaps = 76/326 (23%)

Query: 167 PVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGS 226
           P R  ++  R + +R S R   + P+ +G +R  T        S    L++ G   +   
Sbjct: 663 PARRGRSRSR-TPARRSGRSRSRTPARRGRSRSRT---PRRGRSRSRSLVRRGRSHSRTP 718

Query: 227 Q--AKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQK 284
           Q   + GS  +R + SR +    + +  P   +   S+ R  +             SP+ 
Sbjct: 719 QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL-----------SSPRS 767

Query: 285 KMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERL 344
           K +SR    + +R S SG++          ++     ++S  G+SQ       P    R 
Sbjct: 768 KAKSR----LSLRRSLSGSSPCP------KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRS 817

Query: 345 SAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSPGKKP---AGRKTRESQAAAREDNDPNR 401
           S++PP            P+  SK P +  HSS    P   +G   R+    + + N+  +
Sbjct: 818 SSSPP------------PKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANE--Q 863

Query: 402 DEVPRAQLPTHRPGLPRLSVRRGEFSSS-DPNIRAPQLPGTSEPSAYSPGGLVPRRHAPS 460
              P+               RR  F SS DP +++                  P RH+ S
Sbjct: 864 SVTPQ---------------RRSCFESSPDPELKSR----------------TPSRHSCS 892

Query: 461 GNQQPPVHPPRPERQQQPPGAQGCPR 486
           G+  P V    P RQ     +   P+
Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSPQPK 918



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 100/476 (21%), Positives = 154/476 (32%), Gaps = 58/476 (12%)

Query: 20  KKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWG 79
           K+  SR+ +P      +H        S    S S           S S   +     L G
Sbjct: 244 KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS----------RSRSAAAKTHTTALAG 293

Query: 80  REGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGP 139
           R   P +    +GD           P +     S Q    PE A  + S+  + D +   
Sbjct: 294 RSPSPASGRRGEGDA----------PFSEPGTTSTQRPSSPETATKQPSSP-YEDKDKDK 342

Query: 140 SGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDP--QQPSAKGPT 197
             +     SP   +++S G      P P+ A    ER   S   L   P  Q+P      
Sbjct: 343 KEKSATRPSPSP-ERSSTGP-EPPAPTPLLA----ERHGGSPQPLATTPLSQEPVNPPSE 396

Query: 198 RLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPG- 256
             PT D         LP       ++  S++ P SP+    +   +S        P PG 
Sbjct: 397 ASPTRDRSPPKSPEKLP-------QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449

Query: 257 -RFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALP--QGL 313
            R ++S+P        R       D       SR  G+     +     +    P  +G 
Sbjct: 450 HREISSSPTSKNRSHGRAK----RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGH 505

Query: 314 SRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPK 373
           SR +    ++S    S    GR         S +P  P  +      + +G S+  ++ +
Sbjct: 506 SRSRSPQWRRS---RSAQRWGRSRSPQRRGRSRSPQRPG-WSRSRNTQRRGRSRSARRGR 561

Query: 374 HSSPGKKPAGRKTRESQAAAREDNDPNRDEV---PRAQLPTHRPGLPRLSVRRGEFSSSD 430
             S  + PA R    S+  AR     +R       R++ PT R    R   RRG   S  
Sbjct: 562 SHS--RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT 619

Query: 431 PNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQGCPR 486
           P  R  +   T  P         P R +     + P    R   + + P  +G  R
Sbjct: 620 PARRRSR---TRSPVRRRSRSRSPARRSGRSRSRTPAR--RGRSRSRTPARRGRSR 670



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 70/292 (23%), Positives = 103/292 (35%), Gaps = 64/292 (21%)

Query: 189  QQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCK 248
            QQPSA    + P  +  S+  SS           +  S +   S    + +S  +S   +
Sbjct: 2516 QQPSALAALQ-PAKERRSSSSSSS----------SSSSSSSSSSSSSSSSSSGSSSSDSE 2564

Query: 249  ESYLPVPGRFLTSAPRGLTPVAERPAVGE---LEDSPQKKMQSRAWGKVEVRPSCSGAAA 305
             S LPV            TP A + AV E    E +P K+ +         R S S +++
Sbjct: 2565 GSSLPVQPEVALKRVPSPTP-APKEAVREGRPPEPTPAKRKR---------RSSSSSSSS 2614

Query: 306  AGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGM 365
            + +     S    +    S   +S         +     S++ P PA         PQ +
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSS---------SSSSSSSSSSPSPAK------PGPQAL 2659

Query: 366  SKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT-HRPGLPRLSVRRG 424
                  PK +SP K P G +   S    R+  D  RD    +  P   R   P+ S R  
Sbjct: 2660 ------PKPASPKKPPPGERRSRS---PRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710

Query: 425  EFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476
            + SSS+   R  Q   +  PS         RR  PS         PRP R +
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKR------RRETPS---------PRPMRHR 2747



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 84/382 (21%), Positives = 135/382 (35%), Gaps = 52/382 (13%)

Query: 122  GAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSR 181
            G + EGS+   +  E  P  R     S    +  +  R     P    +  +PE   K+R
Sbjct: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTP---PRRRSSRSSPELTRKAR 1702

Query: 182  WSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSR 241
             S R      S +  +R P     S   SS  P  K    R   S + P    +   TSR
Sbjct: 1703 LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSP----RTKTTSR 1758

Query: 242  QASFHCKESYLPVPGRFLTSAPRGL------------TPVAERPAVGELEDSPQKKMQSR 289
            +             GR  +  PRGL                 R   G  + + +++ +SR
Sbjct: 1759 R-------------GRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR 1805

Query: 290  AWGKV-EVRPSCSGAAAAGALPQGLSR---RKMAGGKKSLGGASQLALGRGFPACGERLS 345
            +  +V   R   SG  +     Q  SR   R+  G  ++   + + +  R  PA  +R S
Sbjct: 1806 SRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKR-S 1864

Query: 346  AAPPEPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVP 405
             +   PAT    S  R   +S++  + + S   ++ +  +T  ++  +R    P      
Sbjct: 1865 RSRASPATHRR-SRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS 1923

Query: 406  RAQLP--THRPGLPRLSVRRGEFSSSDPNI-------RAPQLPGTSEPSAYSPGGLVPRR 456
            R++ P  T R    R    R    S  P +       R P +      S  SP   + RR
Sbjct: 1924 RSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSP---ITRR 1980

Query: 457  HAPSGNQQPPVHPPRPERQQQP 478
               S ++  PV   R   +  P
Sbjct: 1981 R--SRSRTSPVTRRRSRSRTSP 2000



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 26/110 (23%), Positives = 44/110 (40%), Gaps = 5/110 (4%)

Query: 313 LSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKP 372
           L+ +K    + + G +     G  F        A  P P    P+S VR    S+ P   
Sbjct: 127 LNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPK 186

Query: 373 KHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT----HRPGLPR 418
           +     KK  GR++ ES +  RE    ++ +  R++  +    HR   P+
Sbjct: 187 QKKKKKKKDRGRRS-ESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPK 235


>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
           sapiens]
          Length = 780

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 88/361 (24%), Positives = 130/361 (36%), Gaps = 45/361 (12%)

Query: 135 AEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQQPSAK 194
           AE  P GR  LG + G  +  +A    L    PV A     R        R + +Q   K
Sbjct: 406 AEEAPGGR--LGEAEGLMKVEAA---RLSAQDPVVAVAEDGREKPKLPKEREELEQAQIK 460

Query: 195 GPTRLP-THDSDSADESSDL--PLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESY 251
           GP  +P   D   A E + L  P   + +   E  + +P  P  +            E  
Sbjct: 461 GPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEEN 520

Query: 252 LPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAA-AGALP 310
            P P R       G  P  +      L DS ++K +    G+V  RP  + A   AG LP
Sbjct: 521 KP-PSRHAG----GKAPGVQGQMAPPLPDSEREKQEPEQ-GEVGKRPGQAQALEEAGDLP 574

Query: 311 QGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQ 370
           +   +   A G+ ++  A +                 P +    P     RPQ +  + Q
Sbjct: 575 EDPQKVPEADGQPAVQPAKE--------------DLGPGDRGLHP-----RPQAVLSEQQ 615

Query: 371 KPKHSSPGKK-----PAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGE 425
                  G+K     P G    ++   A + +   +  +P A+ P   PGLP     + +
Sbjct: 616 NGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLP-AEKPAPGPGLPPEPREQRD 674

Query: 426 FSSSDPNIRAPQLPGTS---EPSAYSPGGLVPRRHAPSGNQQPPV-HPPRPERQQQPPGA 481
              +  N  A QL G +   +P A  PG   P    P G+ Q  +  P RP    QPP  
Sbjct: 675 VERAGGNQAASQLEGKASALQPPASGPGSGSPLPQ-PWGDAQVILGSPARPPFSFQPPAE 733

Query: 482 Q 482
           Q
Sbjct: 734 Q 734


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 48/185 (25%), Positives = 65/185 (35%), Gaps = 14/185 (7%)

Query: 310 PQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKP 369
           P+G   R+  GG +           +G P  G   S  PP P   P   G  PQG ++  
Sbjct: 36  PEG---RRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKP--EGRPPQGGNQSQ 90

Query: 370 QKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSS 429
             P H    ++P  +   +SQ        P R   P+    +HRP  P     R      
Sbjct: 91  GPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPP-PQGGNQSHRPPPPPGKPERPPPQGG 149

Query: 430 DPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVH--------PPRPERQQQPPGA 481
           + +   P  PG  E      G       +P G  Q P          PP P + Q PP A
Sbjct: 150 NQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPA 209

Query: 482 QGCPR 486
            G P+
Sbjct: 210 GGNPQ 214



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 47/175 (26%), Positives = 59/175 (33%), Gaps = 16/175 (9%)

Query: 320 GGKKSLGGASQLALGRGFPACGERLSAAPP----EPATFPPFSGVRPQGMSKKPQKPKHS 375
           GG +S G         G P  G   S  PP    +P   PP  G + QG    P KP+  
Sbjct: 64  GGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERP 123

Query: 376 SPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPR----LSVRRGEFSSSDP 431
            P     G ++        +   P      ++Q P   PG P         +   + S P
Sbjct: 124 PP---QGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPP 180

Query: 432 NIRAPQLPGTSE---PSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483
               PQ P   E   P    P G         GN Q P  PP  + Q  PP  QG
Sbjct: 181 G--KPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQG 233



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 55/200 (27%), Positives = 72/200 (36%), Gaps = 41/200 (20%)

Query: 292 GKVEVRPSCSGAAAAGALPQG--LSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPP 349
           GK E RP   G  + G  P      R    GG +S G           P  G   S  PP
Sbjct: 76  GKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPP 135

Query: 350 ----EPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVP 405
               +P   PP  G + QG    P KP+   P +   G K+R +++   +   P + E  
Sbjct: 136 PPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQE---GNKSRSARSPPGKPQGPPQQEGN 192

Query: 406 RAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQP 465
           + Q P   PG P+     G       N + PQ P                   P+G  Q 
Sbjct: 193 KPQGPPP-PGKPQGPPPAGG------NPQQPQAP-------------------PAGKPQG 226

Query: 466 PV------HPPRPERQQQPP 479
           P        PPRP + QQPP
Sbjct: 227 PPPPPQGGRPPRPAQGQQPP 246


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 79/340 (23%), Positives = 120/340 (35%), Gaps = 51/340 (15%)

Query: 164 GPG--PVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGIC 221
           GPG  P++    P+  S S+   ++  Q P    P + PT    +  + + LPL +    
Sbjct: 224 GPGRDPLQQDGTPKSIS-SQQPEKIKSQPPGTGKPIQGPTQTPQT--DHAKLPLQR---- 276

Query: 222 RNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDS 281
                 ++P +  K+AD  R  S    +  LP P +     P    P A++P   + +  
Sbjct: 277 ----DASRPQT--KQADIVRGESV---KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPG 327

Query: 282 PQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACG 341
           P K   ++  G  +      G       P G ++       + LG A   A   G     
Sbjct: 328 PAKP-PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA----QPLGPAKPPAQQTG----S 378

Query: 342 ERLSAAPPEPATF--PPFSGVRPQ---GMSKKP-----------QKPKHSSPGKKPAGRK 385
           E+ S+  P P     PP  G  P    G +K P           Q+P   SP K P   K
Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438

Query: 386 TRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPS 445
           T   Q        P   ++P  Q    +    +    +       P    PQ PG ++P 
Sbjct: 439 TPVQQ--------PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP 490

Query: 446 AYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485
              PG   P    P   + PP  P   +   Q PG+   P
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 34/141 (24%), Positives = 52/141 (36%), Gaps = 27/141 (19%)

Query: 349 PEPATFPPFSGVRPQGMSKKPQKPKHSSP-GKKPAGRKTRESQAAAREDNDPNRDEVPRA 407
           P PA  PP    +P      PQ+P  + P  ++P   K    Q    +   P+  +    
Sbjct: 474 PGPAKPPP---QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK---PSPQQPGST 527

Query: 408 QLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPV 467
           + P+ +PG  + S                Q P  ++PSA       P     SG    P+
Sbjct: 528 KPPSQQPGSAKPSA---------------QQPSPAKPSAQQ--STKPVSQTGSGK---PL 567

Query: 468 HPPRPERQQQPPGAQGCPRCI 488
            PP      + P +QG P+ I
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTI 588


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 79/340 (23%), Positives = 120/340 (35%), Gaps = 51/340 (15%)

Query: 164 GPG--PVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGIC 221
           GPG  P++    P+  S S+   ++  Q P    P + PT    +  + + LPL +    
Sbjct: 224 GPGRDPLQQDGTPKSIS-SQQPEKIKSQPPGTGKPIQGPTQTPQT--DHAKLPLQR---- 276

Query: 222 RNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDS 281
                 ++P +  K+AD  R  S    +  LP P +     P    P A++P   + +  
Sbjct: 277 ----DASRPQT--KQADIVRGESV---KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPG 327

Query: 282 PQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACG 341
           P K   ++  G  +      G       P G ++       + LG A   A   G     
Sbjct: 328 PAKP-PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA----QPLGPAKPPAQQTG----S 378

Query: 342 ERLSAAPPEPATF--PPFSGVRPQ---GMSKKP-----------QKPKHSSPGKKPAGRK 385
           E+ S+  P P     PP  G  P    G +K P           Q+P   SP K P   K
Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438

Query: 386 TRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPS 445
           T   Q        P   ++P  Q    +    +    +       P    PQ PG ++P 
Sbjct: 439 TPVQQ--------PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP 490

Query: 446 AYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485
              PG   P    P   + PP  P   +   Q PG+   P
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 34/141 (24%), Positives = 52/141 (36%), Gaps = 27/141 (19%)

Query: 349 PEPATFPPFSGVRPQGMSKKPQKPKHSSP-GKKPAGRKTRESQAAAREDNDPNRDEVPRA 407
           P PA  PP    +P      PQ+P  + P  ++P   K    Q    +   P+  +    
Sbjct: 474 PGPAKPPP---QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK---PSPQQPGST 527

Query: 408 QLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPV 467
           + P+ +PG  + S                Q P  ++PSA       P     SG    P+
Sbjct: 528 KPPSQQPGSAKPSA---------------QQPSPAKPSAQQ--STKPVSQTGSGK---PL 567

Query: 468 HPPRPERQQQPPGAQGCPRCI 488
            PP      + P +QG P+ I
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTI 588


>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 426

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 97/406 (23%), Positives = 135/406 (33%), Gaps = 43/406 (10%)

Query: 80  REGRPGTP-VDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVG 138
           R   PG P V  Q +  D        P A  PPP +     P   A E     WA    G
Sbjct: 12  RTPAPGCPEVAPQPEGTDAPGPAVCSPTARAPPPILPAPQRPPTRAREWEGAAWAAGATG 71

Query: 139 PS-------GRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKN--PERGSKSRWSLRVDPQ 189
                    G   LG  P  +++AS G      PG  RA  +   E G + R +     +
Sbjct: 72  VGAALLALPGSRRLGRVPLTFREASPGP----APGAPRARGSCGREPGPRRRRAPSSAGK 127

Query: 190 QPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKP--GSPKKRADTSRQASFHC 247
           +P+A      P   S           +   + R+ GS  +P  G    R    R    HC
Sbjct: 128 RPAAAARAAPPRQRS-----------LARCLPRSVGSCVRPSVGPSLPRRHCRRHCRCHC 176

Query: 248 KESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAG 307
           +   LP P            P    P  G    S       R   + E  P+  G     
Sbjct: 177 RRRPLPKPPPLQPRLGSASPPRLAAPLAGSRAPS-LSPFPRRCRRRAERSPAGHGL---- 231

Query: 308 ALPQGLSR-RKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMS 366
            LP+ LSR  ++ G ++  GG  +   GR    C      +PP PA  P   G   +  +
Sbjct: 232 PLPRSLSRGGEVVGARRRRGGEERRVRGRR-QGCA---LGSPPIPAG-PAAPGRAGERRA 286

Query: 367 KKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEF 426
            +  + +   PG  P      E                 R    T + G P  ++     
Sbjct: 287 ARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGP 346

Query: 427 SSSDPNIRAPQLPG--TSEPSAYSPGGLVPRR-HAPSGNQQPPVHP 469
             S P+  A ++PG  T+    Y P  L  RR  APS  +  P  P
Sbjct: 347 RLSAPSAEAEEVPGGHTASNPTYEP--LSSRRTKAPSEGRDSPSSP 390


>gi|239742467 PREDICTED: double homeobox, 4-like [Homo sapiens]
          Length = 483

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 97/413 (23%), Positives = 134/413 (32%), Gaps = 76/413 (18%)

Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163
           PA++ P PSV+  P     A    +++   AE    GR         W  + +  L  C 
Sbjct: 44  PASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99

Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203
              P P                  V+ W   ER  + R   R     P  +GP       
Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159

Query: 204 SDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGR 257
           +      + L L         GI   E    + G P+ R     Q  F  + +  P  G 
Sbjct: 160 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRI----QIWFQNRRARHPGQGG 215

Query: 258 FLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRK 317
              +   GL   A  P  G    S      + AWG     P      A GALPQG     
Sbjct: 216 RAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG----- 266

Query: 318 MAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSS- 376
            A   ++   A  L   +  PA  E +S   P    F   +   P G    PQ P+    
Sbjct: 267 -AFVSQAARAAPALQPSQAAPA--EGVSQPAPARGDFAYAAPAPPDGALSHPQAPRWPPH 323

Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAP 436
           PGK             +RED DP RD +P       +PG           + + P  +  
Sbjct: 324 PGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQGQGV 359

Query: 437 QLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485
             P TS+ S +   G  P+       P   + PP  P  P+   +    QG P
Sbjct: 360 LAPPTSQGSPWWGWGRGPQVAGAAWEPQAGEAPPPQPAPPDASARQGQMQGIP 412


>gi|116089331 human immunodeficiency virus type I enhancer binding
            protein 3 [Homo sapiens]
          Length = 2406

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 93/385 (24%), Positives = 127/385 (32%), Gaps = 88/385 (22%)

Query: 139  PSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQQPSAKGPTR 198
            P+ R   G +    + A  G+  L GPG      +P  G      L +DP+      P  
Sbjct: 2068 PTRRWSPGQAESPPRSAPPGKWALAGPG------SPSAGEHGP-GLGLDPRVLFPPAP-- 2118

Query: 199  LPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFH------CKE--- 249
            LP      + E+   P  K    R+      P  P      S    FH       +E   
Sbjct: 2119 LPHKLLSRSPETCASPWQKAE-SRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIF 2177

Query: 250  SYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGAL 309
            S+LP+  + LT AP  L P+     V           Q+R      + P  + A  +G  
Sbjct: 2178 SHLPLHSQHLTRAPCPLIPIGGIQMV-----------QARPGAHPTLLPGPTAAWVSG-- 2224

Query: 310  PQGLSRRKMAGGKKSLGGASQLA-LGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKK 368
                     +GG   L GA +    GR  P      S +P    +    S     G   K
Sbjct: 2225 --------FSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPK 2276

Query: 369  PQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRP-----GLPRLSVRR 423
             ++     PG+ P              D  P+    P    PTH P      LPR    R
Sbjct: 2277 ERERTGGGPGRPP--------------DWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGR 2322

Query: 424  GEFSSSDPNIRAPQLPGTSEPSAYSP-------GGLV----------------PRRH--- 457
                S  P + +P+ P   EPSA  P       G L                 PR     
Sbjct: 2323 RAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDS 2382

Query: 458  -APSGNQQPPVHPPRPERQQQPPGA 481
              PSG+ +P  HP +PE  + PP A
Sbjct: 2383 PKPSGSGEPRAHPHQPE-DRVPPNA 2406


>gi|239744249 PREDICTED: similar to double homeobox, 4 [Homo
           sapiens]
          Length = 483

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 97/413 (23%), Positives = 133/413 (32%), Gaps = 76/413 (18%)

Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163
           PA++ P PSV+  P     A    +++   AE    GR         W  + +  L  C 
Sbjct: 44  PASLCPRPSVKLRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99

Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203
              P P                  V+ W   ER  + R   R     P  +GP       
Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159

Query: 204 SDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGR 257
           +      + L L         GI   E    + G P+ R     Q  F  + +  P  G 
Sbjct: 160 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRI----QIWFQNRRARHPGQGG 215

Query: 258 FLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRK 317
              +   GL   A  P  G    S      + AWG     P      A GALPQG     
Sbjct: 216 RAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG----- 266

Query: 318 MAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSS- 376
            A   ++   A  L   +  PA  E +S   P    F   +   P G    PQ P+    
Sbjct: 267 -AFVSQAARAAPALQPSQAAPA--EGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPH 323

Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAP 436
           PGK             +RED DP RD +P       +PG           + + P  +  
Sbjct: 324 PGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQGQGV 359

Query: 437 QLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485
             P TS+ S +   G  P+       P     PP  P  P+   +    QG P
Sbjct: 360 LAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASARQGQMQGIP 412


>gi|239744248 PREDICTED: similar to double homeobox, 4 [Homo
           sapiens]
          Length = 483

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 97/413 (23%), Positives = 133/413 (32%), Gaps = 76/413 (18%)

Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163
           PA++ P PSV+  P     A    +++   AE    GR         W  + +  L  C 
Sbjct: 44  PASLCPRPSVKLRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99

Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203
              P P                  V+ W   ER  + R   R     P  +GP       
Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159

Query: 204 SDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGR 257
           +      + L L         GI   E    + G P+ R     Q  F  + +  P  G 
Sbjct: 160 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRI----QIWFQNRRARHPGQGG 215

Query: 258 FLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRK 317
              +   GL   A  P  G    S      + AWG     P      A GALPQG     
Sbjct: 216 RAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG----- 266

Query: 318 MAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSS- 376
            A   ++   A  L   +  PA  E +S   P    F   +   P G    PQ P+    
Sbjct: 267 -AFVSQAARAAPALQPSQAAPA--EGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPH 323

Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAP 436
           PGK             +RED DP RD +P       +PG           + + P  +  
Sbjct: 324 PGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQGQGV 359

Query: 437 QLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485
             P TS+ S +   G  P+       P     PP  P  P+   +    QG P
Sbjct: 360 LAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASARQGQMQGIP 412


>gi|239744244 PREDICTED: similar to double homeobox, 4 [Homo
           sapiens]
          Length = 483

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 100/417 (23%), Positives = 134/417 (32%), Gaps = 84/417 (20%)

Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163
           PA++ P PSV+  P     A    +++   AE    GR         W  + +  L  C 
Sbjct: 44  PASLCPRPSVKLRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99

Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGP------- 196
              P P                  V+ W   ER  + R   R     P  +GP       
Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159

Query: 197 ---TRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLP 253
              T   T     A E    P    GI   E    + G P+ R     Q  F  + +  P
Sbjct: 160 TAVTGFQTALLLRAFEKDRFP----GIAAREELARETGLPESRI----QIWFQNRRARHP 211

Query: 254 VPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGL 313
             G    +   GL   A  P  G    S      + AWG     P      A GALPQG 
Sbjct: 212 GQGGRAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG- 266

Query: 314 SRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPK 373
                A   ++   A  L   +  PA  E +S   P    F   +   P G    PQ P+
Sbjct: 267 -----AFVSQAARAAPALQPSQAAPA--EGISQPAPARGDFAYAAPAPPDGALSHPQAPR 319

Query: 374 HSS-PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPN 432
               PGK             +RED DP RD +P       +PG           + + P 
Sbjct: 320 WPPHPGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQ 355

Query: 433 IRAPQLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485
            +    P TS+ S +   G  P+       P     PP  P  P+   +    QG P
Sbjct: 356 GQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASARQGQMQGIP 412


>gi|239744242 PREDICTED: similar to double homeobox, 4 [Homo
           sapiens]
          Length = 483

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 97/413 (23%), Positives = 133/413 (32%), Gaps = 76/413 (18%)

Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163
           PA++ P PSV+  P     A    +++   AE    GR         W  + +  L  C 
Sbjct: 44  PASLCPRPSVKLRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99

Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203
              P P                  V+ W   ER  + R   R     P  +GP       
Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159

Query: 204 SDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGR 257
           +      + L L         GI   E    + G P+ R     Q  F  + +  P  G 
Sbjct: 160 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRI----QIWFQNRRARHPGQGG 215

Query: 258 FLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRK 317
              +   GL   A  P  G    S      + AWG     P      A GALPQG     
Sbjct: 216 RAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG----- 266

Query: 318 MAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSS- 376
            A   ++   A  L   +  PA  E +S   P    F   +   P G    PQ P+    
Sbjct: 267 -AFVSQAARAAPALQPSQAAPA--EGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPH 323

Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAP 436
           PGK             +RED DP RD +P       +PG           + + P  +  
Sbjct: 324 PGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQGQGV 359

Query: 437 QLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485
             P TS+ S +   G  P+       P     PP  P  P+   +    QG P
Sbjct: 360 LAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASARQGQMQGIP 412


>gi|239744240 PREDICTED: similar to double homeobox, 4 [Homo
           sapiens]
          Length = 483

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 97/413 (23%), Positives = 133/413 (32%), Gaps = 76/413 (18%)

Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163
           PA++ P PSV+  P     A    +++   AE    GR         W  + +  L  C 
Sbjct: 44  PASLCPRPSVKLRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99

Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203
              P P                  V+ W   ER  + R   R     P  +GP       
Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159

Query: 204 SDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGR 257
           +      + L L         GI   E    + G P+ R     Q  F  + +  P  G 
Sbjct: 160 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRI----QIWFQNRRARHPGQGG 215

Query: 258 FLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRK 317
              +   GL   A  P  G    S      + AWG     P      A GALPQG     
Sbjct: 216 RAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG----- 266

Query: 318 MAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSS- 376
            A   ++   A  L   +  PA  E +S   P    F   +   P G    PQ P+    
Sbjct: 267 -AFVSQAARAAPALQPSQAAPA--EGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPH 323

Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAP 436
           PGK             +RED DP RD +P       +PG           + + P  +  
Sbjct: 324 PGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQGQGV 359

Query: 437 QLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485
             P TS+ S +   G  P+       P     PP  P  P+   +    QG P
Sbjct: 360 LAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASARQGQMQGIP 412


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 57/232 (24%), Positives = 87/232 (37%), Gaps = 43/232 (18%)

Query: 293 KVEVRPSCSGAAAAGALPQGLSRRKMAGGK---KSLGGASQLALGRGFPACG-------- 341
           K E  P      +A     G +  ++A G+   ++  G+ QL++G+   A G        
Sbjct: 494 KKESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRR 553

Query: 342 --ERLSAAPPEPATFPP-------FSGV--RPQGMSKKPQKPKHSSPGK---KPAGRKTR 387
             ++ + APP+P   PP        SG    P  +S KP     S P +   +P G+ + 
Sbjct: 554 AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSA 613

Query: 388 ESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLP-------G 440
            SQ +A      +   +   Q P H P  P+   +      + PN + P  P       G
Sbjct: 614 PSQLSAPRRYSSSLSPI---QAPNHPP--PQPPTQATPLMHTKPNSQGPPNPMALPSEHG 668

Query: 441 TSEPSAYSPGGLVPRRHAPSGNQQPPVHPPR------PERQQQPPGAQGCPR 486
             +PS   P    P    P G Q P +  P+      PE  Q   G    PR
Sbjct: 669 LEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPR 720


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.132    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,898,529
Number of Sequences: 37866
Number of extensions: 1783927
Number of successful extensions: 10129
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 746
Number of HSP's that attempted gapping in prelim test: 7719
Number of HSP's gapped (non-prelim): 2573
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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