BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|223468690 hypothetical protein LOC100132994 [Homo sapiens] (514 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|223468693 hypothetical protein LOC100130361 [Homo sapiens] 1065 0.0 gi|223468690 hypothetical protein LOC100132994 [Homo sapiens] 1065 0.0 gi|239752343 PREDICTED: hypothetical protein [Homo sapiens] 728 0.0 gi|239746856 PREDICTED: hypothetical protein XP_002343859 [Homo ... 728 0.0 gi|239757832 PREDICTED: hypothetical protein [Homo sapiens] 681 0.0 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 59 1e-08 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 59 1e-08 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 58 2e-08 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 55 2e-07 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 54 3e-07 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 54 3e-07 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 51 2e-06 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 51 3e-06 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 51 3e-06 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 50 5e-06 gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 50 5e-06 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 5e-06 gi|20070376 solute carrier family 38, member 10 isoform b [Homo ... 50 6e-06 gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 50 6e-06 gi|150170670 piccolo isoform 2 [Homo sapiens] 49 8e-06 gi|150378539 piccolo isoform 1 [Homo sapiens] 49 8e-06 gi|169160903 PREDICTED: hypothetical protein [Homo sapiens] 48 2e-05 gi|239742467 PREDICTED: double homeobox, 4-like [Homo sapiens] 48 2e-05 gi|116089331 human immunodeficiency virus type I enhancer bindin... 47 3e-05 gi|239744249 PREDICTED: similar to double homeobox, 4 [Homo sapi... 47 4e-05 gi|239744248 PREDICTED: similar to double homeobox, 4 [Homo sapi... 47 4e-05 gi|239744244 PREDICTED: similar to double homeobox, 4 [Homo sapi... 47 4e-05 gi|239744242 PREDICTED: similar to double homeobox, 4 [Homo sapi... 47 4e-05 gi|239744240 PREDICTED: similar to double homeobox, 4 [Homo sapi... 47 4e-05 gi|54860105 nadrin isoform 2 [Homo sapiens] 47 4e-05 >gi|223468693 hypothetical protein LOC100130361 [Homo sapiens] Length = 514 Score = 1065 bits (2754), Expect = 0.0 Identities = 514/514 (100%), Positives = 514/514 (100%) Query: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG 60 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG Sbjct: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG 60 Query: 61 FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP 120 FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP Sbjct: 61 FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP 120 Query: 121 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS 180 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS Sbjct: 121 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS 180 Query: 181 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS 240 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS Sbjct: 181 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS 240 Query: 241 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC 300 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC Sbjct: 241 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC 300 Query: 301 SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV 360 SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV Sbjct: 301 SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV 360 Query: 361 RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS 420 RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS Sbjct: 361 RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS 420 Query: 421 VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG 480 VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG Sbjct: 421 VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG 480 Query: 481 AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514 AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL Sbjct: 481 AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514 >gi|223468690 hypothetical protein LOC100132994 [Homo sapiens] Length = 514 Score = 1065 bits (2754), Expect = 0.0 Identities = 514/514 (100%), Positives = 514/514 (100%) Query: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG 60 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG Sbjct: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEG 60 Query: 61 FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP 120 FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP Sbjct: 61 FSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFP 120 Query: 121 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS 180 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS Sbjct: 121 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS 180 Query: 181 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS 240 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS Sbjct: 181 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS 240 Query: 241 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC 300 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC Sbjct: 241 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC 300 Query: 301 SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV 360 SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV Sbjct: 301 SGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGV 360 Query: 361 RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS 420 RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS Sbjct: 361 RPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLS 420 Query: 421 VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG 480 VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG Sbjct: 421 VRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPG 480 Query: 481 AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514 AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL Sbjct: 481 AQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514 >gi|239752343 PREDICTED: hypothetical protein [Homo sapiens] Length = 518 Score = 728 bits (1878), Expect = 0.0 Identities = 373/518 (72%), Positives = 407/518 (78%), Gaps = 4/518 (0%) Query: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGV----PGSGDGKSESGFT 56 MSS D+VSVC AG EGG++AG+ TASPGAP HG DL G G GK ESGFT Sbjct: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 Query: 57 DPEGFSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQG 116 DPE FSFESESELIEQGRVVLWG+EGRPGTPVDDQ DYSFYLADEPA I+PP SVQG Sbjct: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 Query: 117 HPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPER 176 HP PEGA A+GS + WAD EVGPS R L SPG+WQQASAG LHL PGP AW+NPER Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 Query: 177 GSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKR 236 GSKSR S +VDPQQPSA+GP L T DSDSADESSDLP+++V I EGSQAKPGSPKK Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 Query: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296 DT + SFH +ESYL V G L S PR LTPV ERPAVGEL+ KKMQS WGK V Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 Query: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356 RPSCSGAA G LP+G RK+A KKSL GA +LAL FPA G+RLSA PP+PA+FPP Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 Query: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416 SGV G S +P++PKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT +P L Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 Query: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476 LSVRRGE+SS DPNIRAPQ+ GTS+PSA++ LVPR HA SG+ QPPVHPPRPERQQ Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 Query: 477 QPPGAQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514 QPPGAQGCPRCI LQREIEDL QLAAMQFLTDKFQDL Sbjct: 481 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL 518 >gi|239746856 PREDICTED: hypothetical protein XP_002343859 [Homo sapiens] Length = 518 Score = 728 bits (1878), Expect = 0.0 Identities = 373/518 (72%), Positives = 407/518 (78%), Gaps = 4/518 (0%) Query: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGV----PGSGDGKSESGFT 56 MSS D+VSVC AG EGG++AG+ TASPGAP HG DL G G GK ESGFT Sbjct: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 Query: 57 DPEGFSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQG 116 DPE FSFESESELIEQGRVVLWG+EGRPGTPVDDQ DYSFYLADEPA I+PP SVQG Sbjct: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 Query: 117 HPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPER 176 HP PEGA A+GS + WAD EVGPS R L SPG+WQQASAG LHL PGP AW+NPER Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 Query: 177 GSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKR 236 GSKSR S +VDPQQPSA+GP L T DSDSADESSDLP+++V I EGSQAKPGSPKK Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 Query: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296 DT + SFH +ESYL V G L S PR LTPV ERPAVGEL+ KKMQS WGK V Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 Query: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356 RPSCSGAA G LP+G RK+A KKSL GA +LAL FPA G+RLSA PP+PA+FPP Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 Query: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416 SGV G S +P++PKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT +P L Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 Query: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476 LSVRRGE+SS DPNIRAPQ+ GTS+PSA++ LVPR HA SG+ QPPVHPPRPERQQ Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 Query: 477 QPPGAQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514 QPPGAQGCPRCI LQREIEDL QLAAMQFLTDKFQDL Sbjct: 481 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL 518 >gi|239757832 PREDICTED: hypothetical protein [Homo sapiens] Length = 503 Score = 681 bits (1756), Expect = 0.0 Identities = 348/490 (71%), Positives = 382/490 (77%), Gaps = 4/490 (0%) Query: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGV----PGSGDGKSESGFT 56 MSS D+VSVC AG EGG++AG+ TASPGAP HG DL G G GK ESGFT Sbjct: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 Query: 57 DPEGFSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQG 116 DPE FSFESESELIEQGRVVLWG+EGRPGTPVDDQ DYSFYLADEPA I+PP SVQG Sbjct: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 Query: 117 HPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPER 176 HP PEGA A+GS + WAD EVGPS R L SPG+WQQASAG LHL PGP AW+NPER Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 Query: 177 GSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKR 236 GSKSR S +VDPQQPSA+GP L T DSDSADESSDLP+++V I EGSQAKPGSPKK Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 Query: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296 DT + SFH +ESYL V G L S PR LTPV ERPAVGEL+ KKMQS WGK V Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 Query: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356 RPSCSGAA G LP+G RK+A KKSL GA +LAL FPA G+RLSA PP+PA+FPP Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 Query: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416 SGV G S +P++PKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT +P L Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 Query: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476 LSVRRGE+SS DPNIRAPQ+ GTS+PSA++ LVPR HA SG+ QPPVHPPRPERQQ Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 Query: 477 QPPGAQGCPR 486 QPPGAQGCPR Sbjct: 481 QPPGAQGCPR 490 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 58.5 bits (140), Expect = 1e-08 Identities = 127/503 (25%), Positives = 157/503 (31%), Gaps = 69/503 (13%) Query: 29 PGAPGAHSHGLDLGVPGSG-----DGKSES----GFTDPEGFSFE--SESELIEQGRVVL 77 PG PG D GVPG +GK G P G + S+ E G V Sbjct: 569 PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 628 Query: 78 WGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAE--GSAENWADA 135 G +G PG P G + AD A PP +QG P EG S Sbjct: 629 KGDQGHPGVP-GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 687 Query: 136 EVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNP----ERGSKSRWSLRVDPQQP 191 E G GRD PG+ +A L PGP A P G R + Sbjct: 688 EEGKEGRDGKPGPPGEPGKAGEPGL----PGPEGARGPPGFKGHTGDSGAPGPRGESGAM 743 Query: 192 SAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESY 251 G LP D D+ P G GS PG P + T Q + Sbjct: 744 GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP-SGTPGQKGSKGENGS 802 Query: 252 LPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQ 311 +PG FL PRG V E P K + G+ P G P Sbjct: 803 PGLPG-FL--GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGE-RGDPGIKGDKG----PP 854 Query: 312 GLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKP-Q 370 G + G G + L +G P GE PP P P F G+R + S + + Sbjct: 855 GGKGQPGDPGIPGHKGHTGLMGPQGLP--GENGPVGPPGPPGQPGFPGLRGESPSMETLR 912 Query: 371 KPKHSSPGKKPAGRKT-----------RESQAAAREDNDPNRDEVPRAQLPTHRPGLPRL 419 + GK+ R + SQ P +D +P P PG P Sbjct: 913 RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQ 972 Query: 420 SVRRGEFSSSDP-------------------NIRAPQLPGTSEPSAYSPGGLVPRRHAPS 460 G P + P +PG Y+ GL P P Sbjct: 973 GGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL-PGIPGPQ 1031 Query: 461 GNQQPPVHPPRPERQQQPPGAQG 483 G P HP P PPG G Sbjct: 1032 GETGPAGHPGLP----GPPGPPG 1050 Score = 39.3 bits (90), Expect = 0.009 Identities = 49/184 (26%), Positives = 65/184 (35%), Gaps = 28/184 (15%) Query: 13 GFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQ 72 G E GK+ R PG PG + G+PG + GF G S + E Sbjct: 684 GIPGEEGKEG--RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS-GAPGPRGES 740 Query: 73 GRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENW 132 G + L G+EG PG D P QG P G + + Sbjct: 741 GAMGLPGQEGLPGKDGD-------------------TGPTGPQGPQGPRGPPGKNGSPG- 780 Query: 133 ADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGP-GPVRAWKNPERGSKSRWSLRVDPQQP 191 + E GPSG G K + S G GP GP + E+G + + P +P Sbjct: 781 SPGEPGPSGTP--GQKGSKGENGSPGLPGFLGPRGP--PGEPGEKGVPGKEGVPGKPGEP 836 Query: 192 SAKG 195 KG Sbjct: 837 GFKG 840 Score = 36.2 bits (82), Expect = 0.073 Identities = 117/522 (22%), Positives = 157/522 (30%), Gaps = 132/522 (25%) Query: 29 PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFS--FESESELIEQGRVVLWGREGRPGT 86 PG PG + G+ G K E+G GF + + E+G + L G +G G Sbjct: 261 PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 320 Query: 87 -----PVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAE-----NWADAE 136 P G L + P P + G P+G + E Sbjct: 321 KGEAGPAGPPG--------LPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGE 372 Query: 137 VGPSGRDVLGHSPGKWQQASAGRL----------HLCGPGPV-------------RAWKN 173 +GP G G K Q+ + G H+ PGP K+ Sbjct: 373 LGPQG--PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKD 430 Query: 174 PERGSKSR---------WSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNE 224 ERG K R DP P GP S LP +G + Sbjct: 431 GERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLP-GPLGTKGDR 489 Query: 225 GSQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQK 284 G+ PGSP R D PG + P P ++ + G Sbjct: 490 GAPGIPGSPGSRGD----------------PGIGVAGPPGPSGPPGDKGSPG-------- 525 Query: 285 KMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERL 344 SR P G PQG + R S G + LA C + Sbjct: 526 ---SRG------LPGFPG-------PQGPAGRDGLSSLLSPGDINLLAK----DVCND-- 563 Query: 345 SAAPPEPATFPPFSGVRPQGMSKKPQKP-KHSSPGKK----------------PAGRK-T 386 PP P P G + G P KP + + GKK P G + Sbjct: 564 --CPPGPPGLPGLPGFK--GDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGE 619 Query: 387 RESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPG-TSEPS 445 R + + D VP P PG P G ++ P I+ PG P Sbjct: 620 RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG--AAGPPGIQGS--PGKEGPPG 675 Query: 446 AYSPGGL--VPRRHAPSGNQQPPVHPPRPERQQQP--PGAQG 483 P GL +P G P P P + +P PG +G Sbjct: 676 PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG 717 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 58.5 bits (140), Expect = 1e-08 Identities = 127/503 (25%), Positives = 157/503 (31%), Gaps = 69/503 (13%) Query: 29 PGAPGAHSHGLDLGVPGSG-----DGKSES----GFTDPEGFSFE--SESELIEQGRVVL 77 PG PG D GVPG +GK G P G + S+ E G V Sbjct: 1122 PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 1181 Query: 78 WGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAE--GSAENWADA 135 G +G PG P G + AD A PP +QG P EG S Sbjct: 1182 KGDQGHPGVP-GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 1240 Query: 136 EVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNP----ERGSKSRWSLRVDPQQP 191 E G GRD PG+ +A L PGP A P G R + Sbjct: 1241 EEGKEGRDGKPGPPGEPGKAGEPGL----PGPEGARGPPGFKGHTGDSGAPGPRGESGAM 1296 Query: 192 SAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESY 251 G LP D D+ P G GS PG P + T Q + Sbjct: 1297 GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP-SGTPGQKGSKGENGS 1355 Query: 252 LPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQ 311 +PG FL PRG V E P K + G+ P G P Sbjct: 1356 PGLPG-FL--GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGE-RGDPGIKGDKG----PP 1407 Query: 312 GLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKP-Q 370 G + G G + L +G P GE PP P P F G+R + S + + Sbjct: 1408 GGKGQPGDPGIPGHKGHTGLMGPQGLP--GENGPVGPPGPPGQPGFPGLRGESPSMETLR 1465 Query: 371 KPKHSSPGKKPAGRKT-----------RESQAAAREDNDPNRDEVPRAQLPTHRPGLPRL 419 + GK+ R + SQ P +D +P P PG P Sbjct: 1466 RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQ 1525 Query: 420 SVRRGEFSSSDP-------------------NIRAPQLPGTSEPSAYSPGGLVPRRHAPS 460 G P + P +PG Y+ GL P P Sbjct: 1526 GGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGL-PGIPGPQ 1584 Query: 461 GNQQPPVHPPRPERQQQPPGAQG 483 G P HP P PPG G Sbjct: 1585 GETGPAGHPGLP----GPPGPPG 1603 Score = 39.3 bits (90), Expect = 0.009 Identities = 49/184 (26%), Positives = 65/184 (35%), Gaps = 28/184 (15%) Query: 13 GFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQ 72 G E GK+ R PG PG + G+PG + GF G S + E Sbjct: 1237 GIPGEEGKEG--RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS-GAPGPRGES 1293 Query: 73 GRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENW 132 G + L G+EG PG D P QG P G + + Sbjct: 1294 GAMGLPGQEGLPGKDGD-------------------TGPTGPQGPQGPRGPPGKNGSPG- 1333 Query: 133 ADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGP-GPVRAWKNPERGSKSRWSLRVDPQQP 191 + E GPSG G K + S G GP GP + E+G + + P +P Sbjct: 1334 SPGEPGPSGTP--GQKGSKGENGSPGLPGFLGPRGP--PGEPGEKGVPGKEGVPGKPGEP 1389 Query: 192 SAKG 195 KG Sbjct: 1390 GFKG 1393 Score = 37.4 bits (85), Expect = 0.033 Identities = 52/191 (27%), Positives = 67/191 (35%), Gaps = 37/191 (19%) Query: 321 GKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVR----PQGMSKKP-QKPKHS 375 G GG+ L GFP PP P P G P G +P ++ + Sbjct: 723 GPPGPGGSPGLPGEIGFPG-----KPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDG 777 Query: 376 SPGKKPAGRKTRESQAAAREDNDPNRDEVPRA------------QLPTHRPGLPRLSVRR 423 PGK P R Q A + +P A Q GLP L R Sbjct: 778 LPGK-PGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDR 836 Query: 424 GEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQ------ 477 GE + P P LPGT+ S ++P +P P G + P P P Q + Sbjct: 837 GEKGEAGP-AGPPGLPGTT--SLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGP 893 Query: 478 -----PPGAQG 483 PPGA+G Sbjct: 894 QGPTGPPGAKG 904 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 57.8 bits (138), Expect = 2e-08 Identities = 58/200 (29%), Positives = 74/200 (37%), Gaps = 14/200 (7%) Query: 292 GKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPP-- 349 GK + P G G P G + G KS S +G P G PP Sbjct: 55 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 114 Query: 350 --EPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRA 407 +P PP G RPQG P KP+ G P G K+R ++ + P + Sbjct: 115 PGKPQGPPPQGGNRPQG-PPPPGKPQ----GPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 169 Query: 408 QLPTHRPGLPRLSVRRGEFSSSDP----NIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQ 463 Q P PG P+ +G P + P G S+ SP G P+ P G Sbjct: 170 QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGK-PQGPPPQGGN 228 Query: 464 QPPVHPPRPERQQQPPGAQG 483 QP PP P + Q PP G Sbjct: 229 QPQGPPPPPGKPQGPPPQGG 248 Score = 53.9 bits (128), Expect = 3e-07 Identities = 67/243 (27%), Positives = 87/243 (35%), Gaps = 19/243 (7%) Query: 253 PVPGRFLTSAPRGLTPVAERPAVGELEDSP-----QKKMQSRAWGKVEVRPSCSGAAAAG 307 P PG+ P+G + R G+ + P Q + GK + P G G Sbjct: 72 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQG 131 Query: 308 ALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSK 367 P G + G KS S +G P G PP P P G PQG K Sbjct: 132 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQG-GK 188 Query: 368 KPQKPKHSSPGKK----PAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRR 423 KPQ P PGK P G K+R SQ+ + P + Q P PG P+ + Sbjct: 189 KPQGPP--PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 246 Query: 424 GEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483 G + P + P PG + G +P G Q P Q PP A G Sbjct: 247 G---GNKP--QGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG 301 Query: 484 CPR 486 P+ Sbjct: 302 NPQ 304 Score = 48.5 bits (114), Expect = 1e-05 Identities = 45/153 (29%), Positives = 58/153 (37%), Gaps = 13/153 (8%) Query: 338 PACGERLSAAPPEPATF---PPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAR 394 P G + PP P PP G +PQG P KP+ G P G K+R ++ Sbjct: 41 PQGGNKPQGPPPPPGKPQGPPPQGGNKPQG-PPPPGKPQ----GPPPQGDKSRSPRSPPG 95 Query: 395 EDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDP----NIRAPQLPGTSEPSAYSPG 450 + P + Q P PG P+ +G P + P G S SP Sbjct: 96 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPP 155 Query: 451 GLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483 G P+ P G QP PP P + Q PP G Sbjct: 156 GK-PQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 187 Score = 45.8 bits (107), Expect = 9e-05 Identities = 68/297 (22%), Positives = 93/297 (31%), Gaps = 39/297 (13%) Query: 188 PQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHC 247 PQ P G + P D + P G G+Q + P Sbjct: 68 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 127 Query: 248 KESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSP-----QKKMQSRAWGKVEVRPSCSG 302 + P PG+ P+G + R G+ + P Q + GK + P G Sbjct: 128 RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 187 Query: 303 AAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRP 362 G P G + G KS S +G P G PP P P G P Sbjct: 188 KKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPP 245 Query: 363 QGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVR 422 QG KPQ P P KP G + + + P + + P Q + G P Sbjct: 246 QG-GNKPQGP---PPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP----- 296 Query: 423 RGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPP 479 + N + PQ P P+G Q P PP+ R +PP Sbjct: 297 ----PPAGGNPQQPQAP-------------------PAGQPQGPPRPPQGGRPSRPP 330 Score = 30.0 bits (66), Expect = 5.3 Identities = 48/209 (22%), Positives = 63/209 (30%), Gaps = 12/209 (5%) Query: 188 PQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHC 247 PQ P G + P D + P G G+Q + P Sbjct: 129 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188 Query: 248 KESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSP-----QKKMQSRAWGKVEVRPSCSG 302 K P PG+ P+G + + G+ + P Q + GK + P G Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 248 Query: 303 AAAAGALPQGLSRRKMA-GGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVR 361 G P G + A GG KS S +G P PP PA G Sbjct: 249 NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPA------GGN 302 Query: 362 PQGMSKKPQKPKHSSPGKKPAGRKTRESQ 390 PQ P P GR +R Q Sbjct: 303 PQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 54.7 bits (130), Expect = 2e-07 Identities = 60/223 (26%), Positives = 76/223 (34%), Gaps = 28/223 (12%) Query: 292 GKVEVRPSCSGAAAAGALPQGLSRR--KMAGGKKSLGGASQLALGRGFPACGERLSAAPP 349 GK E RP G + G P+ GG +S G + G P G S PP Sbjct: 55 GKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPP 114 Query: 350 ----EPATFPPFSGVRPQGMSKKPQKPKHSSPGK------------KPAGRKTRESQAAA 393 +P PP G + QG +P KP+ P KP G + + Sbjct: 115 PRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 174 Query: 394 REDNDPNRDEVP------RAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAY 447 P + E P ++Q P RPG P +G S P R + G Sbjct: 175 GPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGN 234 Query: 448 SPGGLVPRRHAPSG----NQQPPVHPPRPERQQQPPGAQGCPR 486 P G P P G P PP P R Q PP G P+ Sbjct: 235 KPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQ 277 Score = 53.5 bits (127), Expect = 4e-07 Identities = 62/232 (26%), Positives = 82/232 (35%), Gaps = 19/232 (8%) Query: 263 PRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRR--KMAG 320 PR P P G P + GK E +P G + G P+ G Sbjct: 73 PRPGKPEGPPPQGGNQSQGPPPRP-----GKPEGQPPQGGNQSQGPPPRPGKPEGPPPQG 127 Query: 321 GKKSLGGASQLALGRGFPACGERLSAAPP----EPATFPPFSGVRPQGMSKKPQKPKHSS 376 G +S G + G P G S PP +P PP G + QG P KP+ Sbjct: 128 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPP 187 Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRG--EFSSSDPNIR 434 P G +++ + P ++Q P RPG P +G + P+ Sbjct: 188 P---QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPG 244 Query: 435 APQLPGTSE---PSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483 PQ P E P P G P GN Q P+ PP + Q PP QG Sbjct: 245 KPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQG 296 Score = 48.5 bits (114), Expect = 1e-05 Identities = 61/230 (26%), Positives = 82/230 (35%), Gaps = 27/230 (11%) Query: 263 PRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRR--KMAG 320 PR P + P G P + GK E P G + G P+ G Sbjct: 94 PRPGKPEGQPPQGGNQSQGPPPRP-----GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG 148 Query: 321 GKKSLGGASQLALGRGFPACGERLSAAPP----EPATFPPFSGVRPQGMSKKPQKPKHSS 376 G +S G + G P G S PP +P PP G + QG +P KP+ Sbjct: 149 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 208 Query: 377 P--GKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIR 434 P G + G R + N+ + P P H PG P+ G + Sbjct: 209 PQGGNQSQGPPPRPGKPEGPPSQGGNKPQGP----PPH-PGKPQ-----GPPPQEGNKPQ 258 Query: 435 APQLPGTSEPSAYSPGGLVPRRHAP--SGNQQPPVHPPRPERQQQPPGAQ 482 P PG P P G P++ P +G Q P PP+ R +PP Q Sbjct: 259 RPPPPG--RPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQ 306 Score = 47.4 bits (111), Expect = 3e-05 Identities = 44/162 (27%), Positives = 59/162 (36%), Gaps = 23/162 (14%) Query: 342 ERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSP--GKKPAGRKTRESQAAAREDNDP 399 +R P +P PP G + QG +P KP+ P G + G R + + Sbjct: 48 QRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGG 107 Query: 400 NRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAP 459 N ++Q P RPG P +G S P R + G G PR P Sbjct: 108 N-----QSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 162 Query: 460 SG--------NQQPPVHPPRPE--------RQQQPPGAQGCP 485 G +Q PP HP +PE + Q PP G P Sbjct: 163 EGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKP 204 Score = 32.0 bits (71), Expect = 1.4 Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 2/56 (3%) Query: 428 SSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483 S P R PQ G ++P P P P G Q PPRP + + PP G Sbjct: 33 SGKPEGRRPQ--GGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGG 86 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 54.3 bits (129), Expect = 3e-07 Identities = 122/471 (25%), Positives = 146/471 (30%), Gaps = 55/471 (11%) Query: 29 PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88 PGA GA+ G PG + SG P G G G PG P Sbjct: 394 PGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPK-------------GNSGEPGAP- 439 Query: 89 DDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHS 148 +GD EP P VQG P P G + A E GP+G L Sbjct: 440 GSKGDTG-----AKGEPG----PVGVQGPPGPAGEEGKRGARG----EPGPTG---LPGP 483 Query: 149 PGKWQQASAGRLHLCGPGPVRAWKNP--ERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDS 206 PG ++ G G V K P ERGS + P + G LP + Sbjct: 484 PG--ERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541 Query: 207 ADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQA--SFHCKESYLPVPG----RFLT 260 S P K G G +PG P + F + PG R + Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601 Query: 261 SAPRGLTPVAERPAVG-ELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMA 319 P + P + G + P R P G P + Sbjct: 602 GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ 661 Query: 320 GGKKSLG--GASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSP 377 G LG G S RGFP GER PP PA P + P K +P Sbjct: 662 GVPGDLGAPGPSGARGERGFP--GERGVQGPPGPAG-PRGANGAPGNDGAKGDAGAPGAP 718 Query: 378 GKKPA-GRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPN--IR 434 G + A G + + A P D P G P RG P Sbjct: 719 GSQGAPGLQGMPGERGAAGLPGPKGDRGDAG--PKGADGSPGKDGVRGLTGPIGPPGPAG 776 Query: 435 APQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485 AP G S PS P G R AP +P PP P PPGA G P Sbjct: 777 APGDKGESGPSG--PAGPTGARGAPGDRGEPG--PPGPAGFAGPPGADGQP 823 Score = 40.0 bits (92), Expect = 0.005 Identities = 127/528 (24%), Positives = 160/528 (30%), Gaps = 121/528 (22%) Query: 30 GAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPVD 89 G PG DLG PG + E GF G QG G G G P + Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGV----------QGPPGPAGPRGANGAPGN 705 Query: 90 D--QGDVVDYSFYLADEPAA--IVPPPSVQGHPFPEGAAA-EGSAENWADAEVGPSGRDV 144 D +GD A P A P +QG P GAA G + DA GP G D Sbjct: 706 DGAKGD--------AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDA--GPKGAD- 754 Query: 145 LGHSPGK-WQQASAGRLHLCGPGPVRAWKNPE--------RGSKSRWSLRVDPQQPSAKG 195 SPGK + G + GP K G++ R +P P G Sbjct: 755 --GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812 Query: 196 PTRLPTHDSD--SADESSDL-------------------PLMKVGICRNEGSQAKPGSPK 234 P D + E D P+ VG +G++ G P Sbjct: 813 FAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872 Query: 235 KRADTSRQA-------SFHCKESYLPVP-GRFLTSAPRGLTPVAERPAVGELEDSPQKKM 286 S + P P G+ PRG T A RP P Sbjct: 873 ATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAG 932 Query: 287 QSRAWGKVEVRPSCSGAAAAGALP--QGLSRRKMAGGKKSLGGASQLALGRGFP------ 338 + + P G A A P QG++ G++ + G RGFP Sbjct: 933 EKGS-------PGADGPAGAPGTPGPQGIA------GQRGVVGLPGQRGERGFPGLPGPS 979 Query: 339 ----------ACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKP-KHSSPGK--KPAGRK 385 A GER PP P P +G P G S + P SPG+ P + Sbjct: 980 GEPGKQGPSGASGER---GPPGPMGPPGLAG--PPGESGREGAPGAEGSPGRDGSPGAKG 1034 Query: 386 TRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDP----------NIRA 435 R A P P P + G RGE + P Sbjct: 1035 DRGETGPAGPPGAPGAPGAPGPVGPAGKSG------DRGETGPAGPAGPVGPVGARGPAG 1088 Query: 436 PQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483 PQ P + G + H Q P PP +Q P GA G Sbjct: 1089 PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASG 1136 Score = 40.0 bits (92), Expect = 0.005 Identities = 119/505 (23%), Positives = 159/505 (31%), Gaps = 64/505 (12%) Query: 17 EGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVV 76 +G A S GAPG + G G K + G P+G ++ + G Sbjct: 709 KGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKG----ADGSPGKDGVRG 764 Query: 77 LWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAE 136 L G G PG P GD + P P +G P P G A AD + Sbjct: 765 LTGPIGPPG-PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPG-ADGQ 822 Query: 137 VGPSGRDVLGHSPGKWQQASAGRLHLCG-PGPVRAWKNP----ERGSKSRWSL------- 184 G G G + K G G PGP+ P RGS Sbjct: 823 PGAKGEP--GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880 Query: 185 -RVDPQQPSAK-GPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQ 242 RV P PS GP P + E P + G G PG P + Sbjct: 881 GRVGPPGPSGNAGP---PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSP 937 Query: 243 ASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV-RPSCS 301 + + PG T P+G+ +R VG ++ E + S Sbjct: 938 GA----DGPAGAPG---TPGPQGI--AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPS 988 Query: 302 GAAAAGALPQGLSRRKMAG-----GKKSLGGASQLALGRGFP-ACGERLSAAPPEPATFP 355 GA+ P + +AG G++ GA G P A G+R P P P Sbjct: 989 GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048 Query: 356 PFSG----VRPQGMSKKPQKPKHSSPGKK--PAGRKTRESQAAAREDNDPNRDEVPRAQL 409 G V P G S + + P P G + R D ++ R + Sbjct: 1049 GAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRG-I 1107 Query: 410 PTHR--------PGLPRLSVRRGEFSSSDP-NIRAPQLPGTSEPSAYS-----PGGLVPR 455 HR PG P +G +S P R P PG++ PG + P Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGP--PGSAGAPGKDGLNGLPGPIGPP 1165 Query: 456 RHAPSGNQQPPVHPPRPERQQQPPG 480 PV PP P PPG Sbjct: 1166 GPRGRTGDAGPVGPPGPPGPPGPPG 1190 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 53.9 bits (128), Expect = 3e-07 Identities = 59/199 (29%), Positives = 72/199 (36%), Gaps = 10/199 (5%) Query: 292 GKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEP 351 GK + P G G P G + G KS S +G P G PP P Sbjct: 76 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 135 Query: 352 ATFPPFSGVRPQGMSKKPQKPKHSSP-GKKPAG-RKTRESQAAAREDNDPNRDEVPRAQL 409 P G PQG +K P P G P G K+R S++ + P + Q Sbjct: 136 PGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQG 193 Query: 410 PTHRPGLPR-LSVRRGEFSSSDPNIRAPQLP----GTSEPSAYSPGGLVPRRHAPSGNQQ 464 P PG P+ + G P PQ P SA SP G P+ P G Q Sbjct: 194 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG-KPQGPPPQGGNQ 252 Query: 465 PPVHPPRPERQQQPPGAQG 483 P PP P + Q PP G Sbjct: 253 PQGPPPPPGKPQGPPPQGG 271 Score = 52.8 bits (125), Expect = 8e-07 Identities = 70/262 (26%), Positives = 98/262 (37%), Gaps = 32/262 (12%) Query: 253 PVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAW----GKVEVRPSCSGAAAAGA 308 P PG+ P+G P G+ + P + +SR+ GK + P G G Sbjct: 73 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 132 Query: 309 LPQ-GLSRRKMAGGKKSLGGASQLALGRGFPACGE---RLSAAPP-EPATFPPFSGVRPQ 363 P G + G G +G P G+ R S +PP +P PP G +PQ Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192 Query: 364 GMSKKPQKPKHSSP--GKKPAG---------------RKTRESQAAAREDNDPNRDEVPR 406 G P KP+ P G KP G K++ +++ + P + Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ 252 Query: 407 AQLPTHRPGLPR-LSVRRGEFSSSDPNIRAPQLP----GTSEPSAYSPGGLVPRRHAPSG 461 Q P PG P+ + G P PQ P G+ S+ SP G P+ P G Sbjct: 253 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGK-PQGPPPQG 311 Query: 462 NQQPPVHPPRPERQQQPPGAQG 483 QP PP P + Q PP G Sbjct: 312 GNQPQGPPPPPGKPQGPPPQGG 333 Score = 46.6 bits (109), Expect = 5e-05 Identities = 47/175 (26%), Positives = 60/175 (34%), Gaps = 28/175 (16%) Query: 335 RGFPACGERLSAAPPEPATFP----PFSGVRPQGMSKKPQKPKHSSP------------- 377 +G P G PP P P P G +PQG P KP+ P Sbjct: 37 QGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 96 Query: 378 ---GKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPR------LSVRRGEFSS 428 G P G K+R ++ + P + Q P PG P+ + +G Sbjct: 97 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 156 Query: 429 SDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483 P PQ S S PG P+ P G QP PP P + Q PP G Sbjct: 157 GKPQGPPPQGDNKSRSSRSPPG--KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 209 Score = 45.8 bits (107), Expect = 9e-05 Identities = 94/380 (24%), Positives = 118/380 (31%), Gaps = 46/380 (12%) Query: 115 QGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQ--QASAGRLHLCGPGPVRAWK 172 QG P P G +G + GP PGK Q G P P + Sbjct: 48 QGPPSPPGKP-QGPPPQGGNQPQGPPP------PPGKPQGPPPQGGNKPQGPPPPGKPQG 100 Query: 173 NPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAK-PG 231 P +G KSR P+ P K P P + P G G++ + P Sbjct: 101 PPPQGDKSR-----SPRSPPGK-PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 154 Query: 232 SPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAW 291 P K Q + S P PG+ P P G P Sbjct: 155 PPGKPQGPPPQGDNKSRSSRSP-PGK----------PQGPPPQGGNQPQGPPPPP----- 198 Query: 292 GKVEVRPSCSGAAAAGALPQGLSRRKMA-GGKKSLGGASQLALGRGFPACGERLSAAPPE 350 GK + P G G P G + G KS S +G P G PP Sbjct: 199 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP 258 Query: 351 PATFPPFSGVRPQGMSKKPQKPKHSSPGKKP--AGRKTRESQAAAREDNDPNRDEVPRAQ 408 P P G PQG +K P P P G K+R S++ + P + Q Sbjct: 259 PPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ 316 Query: 409 LPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHA--PSGNQQPP 466 P PG P+ +G P P +P P G R A P G Q P Sbjct: 317 GPPPPPGKPQGPPPQGGNKPQGP-------PPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369 Query: 467 VHPPRPERQQQPPGAQGCPR 486 Q PP A G P+ Sbjct: 370 PQQEGNNPQGPPPPAGGNPQ 389 Score = 45.4 bits (106), Expect = 1e-04 Identities = 102/423 (24%), Positives = 132/423 (31%), Gaps = 79/423 (18%) Query: 81 EGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPS 140 +G P P QG ++P PPP P P+G G+ P Sbjct: 48 QGPPSPPGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQG----GNKPQGPPPPGKPQ 99 Query: 141 GRDVLGHS-------PGKWQ-QASAGRLHLCGPGPVRAWKN---PERGSKSRWSLRVDPQ 189 G G PGK Q G GP P P+ G+K PQ Sbjct: 100 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK--------PQ 151 Query: 190 QPSAKGPTRLPTHDSDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQA 243 P G + P D+ SS P K G + +G PG P+ Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN- 210 Query: 244 SFHCKESYLPVPGRFLTSAPRG--LTPVAERPAVGELEDSPQKKMQSRAW----GKVEVR 297 K P PG+ P+G + A P PQ Q + GK + Sbjct: 211 ----KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 266 Query: 298 PSCSGAAAAGALPQGLSRRKMA-GGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356 P G G P G + GG KS S +G P G PP P P Sbjct: 267 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP- 325 Query: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416 G PQG KPQ P P KP G + + + P + + P Q + G Sbjct: 326 -QGPPPQG-GNKPQGP---PPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGP 380 Query: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476 P + N + PQ P P+G Q P PP+ R Sbjct: 381 P---------PPAGGNPQQPQAP-------------------PAGQPQGPPRPPQGGRPS 412 Query: 477 QPP 479 +PP Sbjct: 413 RPP 415 Score = 41.2 bits (95), Expect = 0.002 Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 25/135 (18%) Query: 351 PATFPPFSGVRPQGMSKKPQKPKHSSP--GKKPAGRKTRESQAAAREDNDPNRDEVPRAQ 408 P PP G +PQG P KP+ P G +P G + N+ + P Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP- 94 Query: 409 LPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVH 468 PG P+ +G+ S R+P+ P PG P+ P G QP Sbjct: 95 -----PGKPQGPPPQGDKS------RSPRSP---------PG--KPQGPPPQGGNQPQGP 132 Query: 469 PPRPERQQQPPGAQG 483 PP P + Q PP G Sbjct: 133 PPPPGKPQGPPPQGG 147 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 51.2 bits (121), Expect = 2e-06 Identities = 120/496 (24%), Positives = 160/496 (32%), Gaps = 81/496 (16%) Query: 13 GFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQ 72 G D + G+K SPG PG + +G G K E+G P G +I Sbjct: 290 GKDGDKGEKG-----SPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGI-------VIGT 337 Query: 73 GRVVLWGREGRPGTPVDDQGDVVDYSFY-LADEPAAI-VPPPSVQGHP-FPEGAAAEGSA 129 G + G G PGTP +G+ F L +P +P P G P FP +G Sbjct: 338 GPLGEKGERGYPGTP-GPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDR 396 Query: 130 ENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQ 189 + GPSGRD L PG PGP P + + + P Sbjct: 397 GFPGTSLPGPSGRDGLPGPPG-------------SPGP------PGQPGYTNGIVECQPG 437 Query: 190 QPSAKGPTRLPTHD------SDSADESSDLPLMKVGICRN-------EGSQAKPGSPKKR 236 P +GP +P + + + + R G PG P + Sbjct: 438 PPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAK 497 Query: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAV----GELEDSPQKKMQSRAWG 292 D ++ VPG P+G + +P GE + K G Sbjct: 498 GDRGLPG----RDGVAGVPG------PQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPG 547 Query: 293 KVEVRPSCSGAAAAGALP--QGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPE 350 +P +G A + GL K + G L G G GFP G R PP Sbjct: 548 -FPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFP--GSRGDTGPPG 604 Query: 351 PATFPPFSGVRPQGMSKKPQKP-KHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQL 409 P + P + +G + P P PG K K + P P Q Sbjct: 605 PPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQG 664 Query: 410 PTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHP 469 PG P GE A PG P P G+ G+ PP P Sbjct: 665 DRGFPGTPGRPGLPGEKG-------AVGQPGIGFPGPPGPKGV----DGLPGDMGPPGTP 713 Query: 470 PRPERQQQP--PGAQG 483 RP P PG QG Sbjct: 714 GRPGFNGLPGNPGVQG 729 Score = 43.5 bits (101), Expect = 5e-04 Identities = 117/472 (24%), Positives = 152/472 (32%), Gaps = 75/472 (15%) Query: 29 PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88 PG PG +GVPG E G P G + E G L G G PG P Sbjct: 748 PGIPGTPGEKGSIGVPGV---PGEHGAIGPPGL----QGIRGEPGPPGLPGSVGSPGVP- 799 Query: 89 DDQGDVVDYSFYLADEPAAIVPPPSVQGHPF---PEGAAAEGSAENWADAEV-GPSGRDV 144 P PP QG P P G E + ++ GP G Sbjct: 800 -------------GIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG 846 Query: 145 LGHSPGKWQQASAGRLHLCGPGPVRAWKNPE-RGSKSRWSLRVDPQQPSAKGPT---RLP 200 PG Q+ L PG A P GSK + P QP + GP LP Sbjct: 847 AQGLPGITGQSGLPGL----PGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLP 902 Query: 201 THDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLT 260 D S P G+ ++G PG P D S ++ G+ Sbjct: 903 GEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGS-MDKVDMGSMKGQKGDQGEKGQ--- 958 Query: 261 SAPRGLTPVAERPAVGE--LEDSPQKKMQSRAWGKVEVR--PSCSGAAAAGALPQGLSRR 316 + P+ E+ + G+ P K Q+ G+ + P SG A LP Sbjct: 959 -----IGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLP------ 1007 Query: 317 KMAGGKKSLGGASQLALGRGFPAC-GERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHS 375 G K S+G G G P GE+ P P P G + K +K + Sbjct: 1008 ---GPKGSVG-------GMGLPGTPGEKGVPGIPGPQGSPGLPGDK----GAKGEKGQAG 1053 Query: 376 SPG-KKPAGRKTRESQAAAREDNDP-NRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNI 433 PG P R + Q A P + E +P PG P L G Sbjct: 1054 PPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIP-GMPGSPGLKGSPGSVGYPG--- 1109 Query: 434 RAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485 +P LPG +P +G P P P Q+ PG+ G P Sbjct: 1110 -SPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTP-GPTGPAGQKGEPGSDGIP 1159 Score = 37.4 bits (85), Expect = 0.033 Identities = 45/156 (28%), Positives = 55/156 (35%), Gaps = 27/156 (17%) Query: 354 FPPFSGVRPQGMSKKP-QKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTH 412 FP G P+G P QK PG P + TR A+ +P +P P Sbjct: 62 FPGMQG--PEGPQGPPGQKGDTGEPGL-PGTKGTRGPPGASGYPGNPGLPGIPGQDGPPG 118 Query: 413 RPGLPRLSVRRGEFSSSDP--------NIRAPQLPG----TSEPSAYSPGGL-------- 452 PG+P + +GE P N P LPG E + PG L Sbjct: 119 PPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFP 178 Query: 453 -VPRRHAPSG--NQQPPVHPPRPERQQQPPGAQGCP 485 +P P G Q PV PP PPG G P Sbjct: 179 GIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPP 214 Score = 34.7 bits (78), Expect = 0.21 Identities = 118/512 (23%), Positives = 160/512 (31%), Gaps = 80/512 (15%) Query: 29 PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTP- 87 PG PG G+PG K E G P G + G G PG P Sbjct: 108 PGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFA-------------GNPGPPGLPG 154 Query: 88 -VDDQGDVVDY--SFYLADE------PAAIVPP--PSVQGHPFPEGAAAEGSAEN--WAD 134 D G+++ + L E P PP P +QG P G Sbjct: 155 MKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPP 214 Query: 135 AEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVR-----AWKNPERGSKSRWSLRVDP- 188 E G G G K Q +G + G V+ A K E+G K + P Sbjct: 215 GEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKG-EKGQKGEPGFQGMPG 273 Query: 189 ----QQPSAKGPTRLPTHDSDSADESS-DLP--------LMKVGICRNEGSQAKPGSPKK 235 +P GP P D D ++ S P + + G +G PG P Sbjct: 274 VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGI 333 Query: 236 RADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVE 295 T + Y PG P+G + +P L Q+ A G Sbjct: 334 VIGTGPLGE-KGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGL----PVPGQAGAPGFPG 388 Query: 296 VRPSCSGAAAAG-ALPQGLSRRKMAGGKKSLGGASQLALGRGFPAC--GERLSAAPPEPA 352 R G +LP R + G S G Q G C G PP Sbjct: 389 ERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIP 448 Query: 353 TFPPFSGVRPQGMSKKPQKPK----------HSSPGKK-PAGRKTRESQAAAREDND-PN 400 P F G + +K QK + PG + P G Q A+ D P Sbjct: 449 GQPGFIG----EIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPG 504 Query: 401 RDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPS 460 RD V P PGL +GE ++R G +P G+ R +P Sbjct: 505 RDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKG--DPGFPGQPGMTGRAGSPG 562 Query: 461 GNQQPPVHPPRP-------ERQQQPPGAQGCP 485 + P + P+ + ++ PPG G P Sbjct: 563 RDGHPGLPGPKGSPGSVGLKGERGPPGGVGFP 594 Score = 32.0 bits (71), Expect = 1.4 Identities = 62/251 (24%), Positives = 79/251 (31%), Gaps = 47/251 (18%) Query: 16 LEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRV 75 L G K PG+PG +G+PG G G+ S E+G Sbjct: 1062 LRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYP-GSPGLPGEKGDK 1120 Query: 76 VLWGREGRPGT-----------PVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAA 124 L G +G PG P G + A P + G FP Sbjct: 1121 GLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPG 1180 Query: 125 AEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGP-----------GPVRAWKN 173 A+G + + EVG G L SPG S G GP P A + Sbjct: 1181 AKG--DKGSKGEVGFPG---LAGSPG--IPGSKGEQGFMGPPGPQGQPGLPGSPGHATEG 1233 Query: 174 P--ERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPG 231 P +RG + + L P P GP LP D D+ N G PG Sbjct: 1234 PKGDRGPQGQPGL---PGLPGPMGPPGLPGIDGVKGDKG------------NPGWPGAPG 1278 Query: 232 SPKKRADTSRQ 242 P + D Q Sbjct: 1279 VPGPKGDPGFQ 1289 Score = 30.8 bits (68), Expect = 3.1 Identities = 27/77 (35%), Positives = 30/77 (38%), Gaps = 10/77 (12%) Query: 29 PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88 PG PG G D G PG +G T P GF G L G G PGTP Sbjct: 1392 PGPPGIP--GFD-GAPGQKGEMGPAGPTGPRGFPGPP-------GPDGLPGSMGPPGTPS 1441 Query: 89 DDQGDVVDYSFYLADEP 105 D G +V D+P Sbjct: 1442 VDHGFLVTRHSQTIDDP 1458 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 50.8 bits (120), Expect = 3e-06 Identities = 127/501 (25%), Positives = 166/501 (33%), Gaps = 104/501 (20%) Query: 29 PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88 PG PG D GVPG G GF E S G L G G PGTP Sbjct: 671 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS----PGAQGLQGPRGLPGTPG 726 Query: 89 DD--QGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSG-RDVL 145 D +G A PA PP QG P +G E A A GP G R + Sbjct: 727 TDGPKG---------ASGPAG---PPGAQGPPGLQGMPGERGAAGIA----GPKGDRGDV 770 Query: 146 GHSPGKWQQASAGRLHLCGP--GPVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203 G + G L GP P A N E+G V P P+ R Sbjct: 771 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG-------EVGPPGPAGSAGAR----- 818 Query: 204 SDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVP-GRFLTSA 262 + P G G+ +PG+ ++ + ++ ++ P P G Sbjct: 819 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG-----DAGAPGPQGPSGAPG 873 Query: 263 PRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGK 322 P+G T V + P A G+V S G P G S + G Sbjct: 874 PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG--PPGPSGK---DGP 928 Query: 323 KSLGGASQLALGRGFPACGERLSAAPP----EPATFPPFSGVR----PQGMSKK------ 368 K G S G P G + A PP EP P SG PQG++ + Sbjct: 929 KGARGDSGPPGRAGEP--GLQGPAGPPGEKGEPGDDGP-SGAEGPPGPQGLAGQRGIVGL 985 Query: 369 -PQKPKHSSPG-KKPAGRKTRESQAAARED----------------NDPNRDEVPRAQLP 410 Q+ + PG P+G ++ A D +P R+ P A P Sbjct: 986 PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 1045 Query: 411 THRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQ------- 463 R G + RGE + + AP PG P + P G P+G Q Sbjct: 1046 PGRDGAAGVKGDRGETGA----VGAPGAPG--PPGSPGPAG-------PTGKQGDRGEAG 1092 Query: 464 -QPPVHPPRPERQQQPPGAQG 483 Q P+ P P + G QG Sbjct: 1093 AQGPMGPSGPAGARGIQGPQG 1113 Score = 45.4 bits (106), Expect = 1e-04 Identities = 125/496 (25%), Positives = 158/496 (31%), Gaps = 113/496 (22%) Query: 18 GGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTD---PEGFSFESESELIEQGR 74 G + + G PG G PG+ K E+G T PEG E G Sbjct: 342 GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ-GPRGEPGTPGS 400 Query: 75 VVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPP--PSVQGHPFPEGAAAEGSAENW 132 G G PGT D + + A P P P +G P P+GA Sbjct: 401 PGPAGASGNPGT------DGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP------ 448 Query: 133 ADAEVGPSGRDVLGHSPG----KWQQASAGRLHLCGP----GPV-RAWKNPERGSKSRWS 183 +GP G+ PG K +Q G GP GP K RG Sbjct: 449 ----LGPKGQT---GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 501 Query: 184 LRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQA 243 P + A G P D + + + G+ +G+ PG P + Sbjct: 502 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG------ 555 Query: 244 SFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGA 303 +PG RGLT RP + PQ K+ + RP G Sbjct: 556 ----------LPGA------RGLTG---RPG----DAGPQGKVGPSGAPGEDGRPGPPGP 592 Query: 304 AAA----GAL----PQGLSRRKMAGGKKSLGGASQLALGRGFPAC-GERLSAAPPEPATF 354 A G + P+G + G+K L GA L RG P GE +A PP PA Sbjct: 593 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL---RGLPGKDGETGAAGPPGPAGP 649 Query: 355 PPFSGVR----PQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLP 410 G + P G P P G KP + P P P Sbjct: 650 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG------------DQGVPGEAGAPGLVGP 697 Query: 411 THRPGLPRLSVRRGEFSSSDPNIRAPQ-LPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHP 469 G P RG S ++ P+ LPGT P P G SG P Sbjct: 698 RGERGFPG---ERG--SPGAQGLQGPRGLPGT--PGTDGPKGA-------SG-------P 736 Query: 470 PRPERQQQPPGAQGCP 485 P Q PPG QG P Sbjct: 737 AGPPGAQGPPGLQGMP 752 Score = 38.5 bits (88), Expect = 0.015 Identities = 126/504 (25%), Positives = 158/504 (31%), Gaps = 100/504 (19%) Query: 13 GFDLEGGK--KAGSR-----------TASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPE 59 G D E GK KAG R +PG PG H G PG K E+G + Sbjct: 252 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR---GYPGLDGAKGEAGAPGVK 308 Query: 60 GFSFE-----SESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSV 114 G S S + +G GR G G D +P PP V Sbjct: 309 GESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND---------GQPGPAGPPGPV 359 Query: 115 ---QGHPFPEGAAAEGSAENWADAEVGPSG-RDVLGHSPGKWQQASAGRLHLCGPGPVRA 170 G FP A+G E GP+G R G + + + G PGP A Sbjct: 360 GPAGGPGFPGAPGAKG--------EAGPTGARGPEGAQGPRGEPGTPG-----SPGPAGA 406 Query: 171 WKNP-------ERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRN 223 NP +GS + P P +GP P + + GI Sbjct: 407 SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP---PGPQGATGPLGPKGQTGEPGIAGF 463 Query: 224 EGSQAKPGSPKKRADTSR--QASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDS 281 +G Q G P A K PG P G P ER A G Sbjct: 464 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGV---GPIG--PPGERGAPG----- 513 Query: 282 PQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACG 341 +R + + GA P GL+ K A G G L RG Sbjct: 514 ------NRGFPGQDGLAGPKGAPGERG-PSGLAGPKGANGDPGRPGEPGLPGARGLTG-- 564 Query: 342 ERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNR 401 R A P+ P SG G +P P +P + A E Sbjct: 565 -RPGDAGPQGKVGP--SGA--PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 619 Query: 402 DEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSG 461 +P A PGL L + GE ++ P PG + P+ P PSG Sbjct: 620 KGLPGA------PGLRGLPGKDGETGAAGP-------PGPAGPAGERGEQGAP---GPSG 663 Query: 462 NQQPPVHPPRPERQQQPPGAQGCP 485 Q P PP P + PG QG P Sbjct: 664 FQGLP-GPPGPPGEGGKPGDQGVP 686 Score = 34.3 bits (77), Expect = 0.28 Identities = 116/500 (23%), Positives = 147/500 (29%), Gaps = 98/500 (19%) Query: 17 EGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDG---------KSESGFTDPEGFSFESES 67 +GG+ PG GA+ ++G PG + E+G P GF+ + Sbjct: 782 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 841 Query: 68 E-----LIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEG 122 + EQG G G PG P G P + P +G P G Sbjct: 842 DGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQG------PTGVTGPKGARGAQGPPG 894 Query: 123 AAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRW 182 A A VGP G + PG G GP R P G Sbjct: 895 ATGFPGAA----GRVGPPGSNGNPGPPG-----PPGPSGKDGPKGARGDSGPP-GRAGEP 944 Query: 183 SLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMK------VGICRNEGSQAKPGSPKKR 236 L+ P KG P D S E P VG+ G + PG P Sbjct: 945 GLQGPAGPPGEKGE---PGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 1001 Query: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296 + +Q + P PG P GLT A P Sbjct: 1002 GEPGKQGAPGASGDRGP-PG---PVGPPGLTGPAGEPG---------------------- 1035 Query: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356 R GA G R A G K G + G P P PA Sbjct: 1036 REGSPGA-------DGPPGRDGAAGVKGDRGETGAVGAPGAPG-----PPGSPGPAGPTG 1083 Query: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHR--- 413 G R + ++ P P PAG + + R D + R L HR Sbjct: 1084 KQGDRGEAGAQGPMGP------SGPAGARGIQGPQGPRGDKGEAGEPGERG-LKGHRGFT 1136 Query: 414 -----PGLPRLSVRRGEFSSSDPN-IRAPQLPGTSEPSAYSPGGLVPRRHAPSG--NQQP 465 PG P S +G + P+ R P PG PS +P P G + Sbjct: 1137 GLQGLPGPPGPSGDQGASGPAGPSGPRGP--PGPVGPSGKDGANGIPGPIGPPGPRGRSG 1194 Query: 466 PVHPPRPERQQQPPGAQGCP 485 P P PPG G P Sbjct: 1195 ETGPAGPPGNPGPPGPPGPP 1214 Score = 30.0 bits (66), Expect = 5.3 Identities = 37/143 (25%), Positives = 52/143 (36%), Gaps = 22/143 (15%) Query: 16 LEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRV 75 ++G + +PGAPG G G + E+G P G S + + I QG Sbjct: 1054 VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI-QGPQ 1112 Query: 76 VLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWA-- 133 G +G G P ++G F +QG P P G + + A A Sbjct: 1113 GPRGDKGEAGEP-GERGLKGHRGF------------TGLQGLPGPPGPSGDQGASGPAGP 1159 Query: 134 ------DAEVGPSGRDVLGHSPG 150 VGPSG+D PG Sbjct: 1160 SGPRGPPGPVGPSGKDGANGIPG 1182 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 50.8 bits (120), Expect = 3e-06 Identities = 127/501 (25%), Positives = 166/501 (33%), Gaps = 104/501 (20%) Query: 29 PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88 PG PG D GVPG G GF E S G L G G PGTP Sbjct: 602 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS----PGAQGLQGPRGLPGTPG 657 Query: 89 DD--QGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSG-RDVL 145 D +G A PA PP QG P +G E A A GP G R + Sbjct: 658 TDGPKG---------ASGPAG---PPGAQGPPGLQGMPGERGAAGIA----GPKGDRGDV 701 Query: 146 GHSPGKWQQASAGRLHLCGP--GPVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203 G + G L GP P A N E+G V P P+ R Sbjct: 702 GEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKG-------EVGPPGPAGSAGAR----- 749 Query: 204 SDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVP-GRFLTSA 262 + P G G+ +PG+ ++ + ++ ++ P P G Sbjct: 750 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKG-----DAGAPGPQGPSGAPG 804 Query: 263 PRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGK 322 P+G T V + P A G+V S G P G S + G Sbjct: 805 PQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG--PPGPSGK---DGP 859 Query: 323 KSLGGASQLALGRGFPACGERLSAAPP----EPATFPPFSGVR----PQGMSKK------ 368 K G S G P G + A PP EP P SG PQG++ + Sbjct: 860 KGARGDSGPPGRAGEP--GLQGPAGPPGEKGEPGDDGP-SGAEGPPGPQGLAGQRGIVGL 916 Query: 369 -PQKPKHSSPG-KKPAGRKTRESQAAARED----------------NDPNRDEVPRAQLP 410 Q+ + PG P+G ++ A D +P R+ P A P Sbjct: 917 PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 976 Query: 411 THRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQ------- 463 R G + RGE + + AP PG P + P G P+G Q Sbjct: 977 PGRDGAAGVKGDRGETGA----VGAPGAPG--PPGSPGPAG-------PTGKQGDRGEAG 1023 Query: 464 -QPPVHPPRPERQQQPPGAQG 483 Q P+ P P + G QG Sbjct: 1024 AQGPMGPSGPAGARGIQGPQG 1044 Score = 45.4 bits (106), Expect = 1e-04 Identities = 125/496 (25%), Positives = 158/496 (31%), Gaps = 113/496 (22%) Query: 18 GGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTD---PEGFSFESESELIEQGR 74 G + + G PG G PG+ K E+G T PEG E G Sbjct: 273 GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ-GPRGEPGTPGS 331 Query: 75 VVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPP--PSVQGHPFPEGAAAEGSAENW 132 G G PGT D + + A P P P +G P P+GA Sbjct: 332 PGPAGASGNPGT------DGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP------ 379 Query: 133 ADAEVGPSGRDVLGHSPG----KWQQASAGRLHLCGP----GPV-RAWKNPERGSKSRWS 183 +GP G+ PG K +Q G GP GP K RG Sbjct: 380 ----LGPKGQT---GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG 432 Query: 184 LRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQA 243 P + A G P D + + + G+ +G+ PG P + Sbjct: 433 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG------ 486 Query: 244 SFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGA 303 +PG RGLT RP + PQ K+ + RP G Sbjct: 487 ----------LPGA------RGLTG---RPG----DAGPQGKVGPSGAPGEDGRPGPPGP 523 Query: 304 AAA----GAL----PQGLSRRKMAGGKKSLGGASQLALGRGFPAC-GERLSAAPPEPATF 354 A G + P+G + G+K L GA L RG P GE +A PP PA Sbjct: 524 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL---RGLPGKDGETGAAGPPGPAGP 580 Query: 355 PPFSGVR----PQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLP 410 G + P G P P G KP + P P P Sbjct: 581 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG------------DQGVPGEAGAPGLVGP 628 Query: 411 THRPGLPRLSVRRGEFSSSDPNIRAPQ-LPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHP 469 G P RG S ++ P+ LPGT P P G SG P Sbjct: 629 RGERGFPG---ERG--SPGAQGLQGPRGLPGT--PGTDGPKGA-------SG-------P 667 Query: 470 PRPERQQQPPGAQGCP 485 P Q PPG QG P Sbjct: 668 AGPPGAQGPPGLQGMP 683 Score = 38.5 bits (88), Expect = 0.015 Identities = 126/504 (25%), Positives = 158/504 (31%), Gaps = 100/504 (19%) Query: 13 GFDLEGGK--KAGSR-----------TASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPE 59 G D E GK KAG R +PG PG H G PG K E+G + Sbjct: 183 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHR---GYPGLDGAKGEAGAPGVK 239 Query: 60 GFSFE-----SESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSV 114 G S S + +G GR G G D +P PP V Sbjct: 240 GESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGND---------GQPGPAGPPGPV 290 Query: 115 ---QGHPFPEGAAAEGSAENWADAEVGPSG-RDVLGHSPGKWQQASAGRLHLCGPGPVRA 170 G FP A+G E GP+G R G + + + G PGP A Sbjct: 291 GPAGGPGFPGAPGAKG--------EAGPTGARGPEGAQGPRGEPGTPG-----SPGPAGA 337 Query: 171 WKNP-------ERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRN 223 NP +GS + P P +GP P + + GI Sbjct: 338 SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP---PGPQGATGPLGPKGQTGEPGIAGF 394 Query: 224 EGSQAKPGSPKKRADTSR--QASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDS 281 +G Q G P A K PG P G P ER A G Sbjct: 395 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGV---GPIG--PPGERGAPG----- 444 Query: 282 PQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACG 341 +R + + GA P GL+ K A G G L RG Sbjct: 445 ------NRGFPGQDGLAGPKGAPGERG-PSGLAGPKGANGDPGRPGEPGLPGARGLTG-- 495 Query: 342 ERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNR 401 R A P+ P SG G +P P +P + A E Sbjct: 496 -RPGDAGPQGKVGP--SGA--PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 550 Query: 402 DEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSG 461 +P A PGL L + GE ++ P PG + P+ P PSG Sbjct: 551 KGLPGA------PGLRGLPGKDGETGAAGP-------PGPAGPAGERGEQGAP---GPSG 594 Query: 462 NQQPPVHPPRPERQQQPPGAQGCP 485 Q P PP P + PG QG P Sbjct: 595 FQGLP-GPPGPPGEGGKPGDQGVP 617 Score = 34.3 bits (77), Expect = 0.28 Identities = 116/500 (23%), Positives = 147/500 (29%), Gaps = 98/500 (19%) Query: 17 EGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDG---------KSESGFTDPEGFSFESES 67 +GG+ PG GA+ ++G PG + E+G P GF+ + Sbjct: 713 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 772 Query: 68 E-----LIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEG 122 + EQG G G PG P G P + P +G P G Sbjct: 773 DGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQG------PTGVTGPKGARGAQGPPG 825 Query: 123 AAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRW 182 A A VGP G + PG G GP R P G Sbjct: 826 ATGFPGAA----GRVGPPGSNGNPGPPG-----PPGPSGKDGPKGARGDSGPP-GRAGEP 875 Query: 183 SLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMK------VGICRNEGSQAKPGSPKKR 236 L+ P KG P D S E P VG+ G + PG P Sbjct: 876 GLQGPAGPPGEKGE---PGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932 Query: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296 + +Q + P PG P GLT A P Sbjct: 933 GEPGKQGAPGASGDRGP-PG---PVGPPGLTGPAGEPG---------------------- 966 Query: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356 R GA G R A G K G + G P P PA Sbjct: 967 REGSPGA-------DGPPGRDGAAGVKGDRGETGAVGAPGAPG-----PPGSPGPAGPTG 1014 Query: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHR--- 413 G R + ++ P P PAG + + R D + R L HR Sbjct: 1015 KQGDRGEAGAQGPMGP------SGPAGARGIQGPQGPRGDKGEAGEPGERG-LKGHRGFT 1067 Query: 414 -----PGLPRLSVRRGEFSSSDPN-IRAPQLPGTSEPSAYSPGGLVPRRHAPSG--NQQP 465 PG P S +G + P+ R P PG PS +P P G + Sbjct: 1068 GLQGLPGPPGPSGDQGASGPAGPSGPRGP--PGPVGPSGKDGANGIPGPIGPPGPRGRSG 1125 Query: 466 PVHPPRPERQQQPPGAQGCP 485 P P PPG G P Sbjct: 1126 ETGPAGPPGNPGPPGPPGPP 1145 Score = 30.0 bits (66), Expect = 5.3 Identities = 37/143 (25%), Positives = 52/143 (36%), Gaps = 22/143 (15%) Query: 16 LEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRV 75 ++G + +PGAPG G G + E+G P G S + + I QG Sbjct: 985 VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI-QGPQ 1043 Query: 76 VLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWA-- 133 G +G G P ++G F +QG P P G + + A A Sbjct: 1044 GPRGDKGEAGEP-GERGLKGHRGF------------TGLQGLPGPPGPSGDQGASGPAGP 1090 Query: 134 ------DAEVGPSGRDVLGHSPG 150 VGPSG+D PG Sbjct: 1091 SGPRGPPGPVGPSGKDGANGIPG 1113 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 50.1 bits (118), Expect = 5e-06 Identities = 121/486 (24%), Positives = 165/486 (33%), Gaps = 93/486 (19%) Query: 17 EGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVV 76 +G + R +PG PGA G+PG E G P+G + ++I Sbjct: 1304 DGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKG-EPGAPGQVIGGEGPG 1362 Query: 77 LWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAE 136 L GR+G PG P G P + P +G P G A +G + E Sbjct: 1363 LPGRKGDPG-PSGPPG------------PRGPLGDPGPRGPPGLPGTAMKG--DKGDRGE 1407 Query: 137 VGPSGRDVLGHSPGKWQQASAGRLHLCGP-GPV-RAWKNPERGSKSRWS--LRVDPQQPS 192 GP G G +PG + G GP GPV K E+G + L P P Sbjct: 1408 RGPPGPGEGGIAPG--EPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPG 1465 Query: 193 AKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYL 252 +GP P D PL + G +G + PG Sbjct: 1466 EQGPRGPPGAIGPKGDRGFPGPLGEAG---EKGERGPPG--------------------- 1501 Query: 253 PVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKV--EVRPSCSGAAAAGALP 310 + RGL VA RP E P + G+ P+ G A AG P Sbjct: 1502 -------PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAG--P 1552 Query: 311 QGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQ 370 +G K G GA+ + RG P + P P P G P G++ + Sbjct: 1553 KG---EKGDVGPAGPRGATGVQGERGPPGL---VLPGDPGPKGDPGDRG--PIGLTGRAG 1604 Query: 371 KPKHSS-PGKK----------PAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRL 419 P S PG+K P G + R+ + + D P D PGLP Sbjct: 1605 PPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGD-----------PGLPGK 1653 Query: 420 SVRRGEFSSSDPNIRAP--QLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPER-QQ 476 + RG P +R P + +P G P P G++ P P P R Sbjct: 1654 AGERG--LRGAPGVRGPVGEKGDQGDPGEDGRNG-SPGSSGPKGDRGEPGPPGPPGRLVD 1710 Query: 477 QPPGAQ 482 PGA+ Sbjct: 1711 TGPGAR 1716 Score = 43.5 bits (101), Expect = 5e-04 Identities = 120/486 (24%), Positives = 148/486 (30%), Gaps = 97/486 (19%) Query: 29 PGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRPGTPV 88 PG PG G+PG G E+G G E + E EQGR G G PG P Sbjct: 2036 PGKPGIP------GLPGRAGGVGEAGRPGERGERGE-KGERGEQGRDGPPGLPGTPGPP- 2087 Query: 89 DDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSG-RDVLGH 147 G V DEP P + G P G E ++ + GP G R V G Sbjct: 2088 GPPGPKVS-----VDEPG-----PGLSGEQGPPGLKG-AKGEPGSNGDQGPKGDRGVPGI 2136 Query: 148 SPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSA 207 + + PGP NP G + +P +GP P Sbjct: 2137 KGDRGE-----------PGPRGQDGNP--GLPGERGMAGPEGKPGLQGPRGPPGPVGGHG 2183 Query: 208 DESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLT 267 D P G+ G Q G + +T PGR LT P G Sbjct: 2184 DPG---PPGAPGLAGPAGPQGPSGLKGEPGETGP-------------PGRGLTG-PTGAV 2226 Query: 268 PVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGG 327 + P L PQ P G P G R A GK G Sbjct: 2227 GLPGPPGPSGLV-GPQGS------------PGLPGQVGETGKP-GAPGRDGASGKDGDRG 2272 Query: 328 ASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKH------SSPGKK- 380 + + G P G P P P + V G + P PG K Sbjct: 2273 SPGVPGSPGLP--GPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKG 2330 Query: 381 ----PAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRA- 435 P R + A E DP D A P G P + V P ++ Sbjct: 2331 DRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGD 2390 Query: 436 ---PQLPGTSEPSAYSPGGLVPR----RHAPSGNQ-----------QPPVHPPRPERQQQ 477 P LPG + PG PR + PSG + P+ PP P Sbjct: 2391 LGLPGLPGAPGVVGF-PGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVG 2449 Query: 478 PPGAQG 483 PPGA G Sbjct: 2450 PPGASG 2455 Score = 37.4 bits (85), Expect = 0.033 Identities = 113/494 (22%), Positives = 142/494 (28%), Gaps = 92/494 (18%) Query: 15 DLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGR 74 D G + G G D G+PG+ + GF P Sbjct: 1710 DTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPP--------------- 1754 Query: 75 VVLWGREGRPGT--PVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEG--AAAEGSAE 130 G +G PG P ++GD PP + G +G AA S Sbjct: 1755 ----GPQGDPGVRGPAGEKGD---------------RGPPGLDGRSGLDGKPGAAGPSGP 1795 Query: 131 NWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPG--PVRAWKNPERGSKSRWSLRVDP 188 N A + G GRD L PG G L GP P K E G +P Sbjct: 1796 NGAAGKAGDPGRDGL---PG-----LRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEP 1847 Query: 189 QQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCK 248 P G S E D P + G G Q PG P Sbjct: 1848 GDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLP--------------- 1892 Query: 249 ESYLPVPGRFLTSAPRGLTPVAERPAVGELEDS--PQKKMQSRAWGKVEVRPSCSGAAAA 306 + PG+ P G P +R G + P ++ G V P+ Sbjct: 1893 -GPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSV---PNVDRLLET 1948 Query: 307 GALPQGLSRRKMAGGKKSLGGASQLALGRGFPA--CGERLSAAPPEPATFPPFSGVRPQG 364 + R + +S G + R P GE+ P FP G++ Sbjct: 1949 AGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDR 2008 Query: 365 MSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRG 424 PQ P PG R A E P +P G P RG Sbjct: 2009 GDPGPQGP----PGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERG 2064 Query: 425 EFSSSDPNIR--APQLPGTSEPSAYSPGGLVPRRHAP------SGNQQPP-----VHPPR 471 E R P LPGT P PG P+ SG Q PP P Sbjct: 2065 EKGERGEQGRDGPPGLPGTPGP----PGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPG 2120 Query: 472 PERQQQPPGAQGCP 485 Q P G +G P Sbjct: 2121 SNGDQGPKGDRGVP 2134 Score = 35.4 bits (80), Expect = 0.13 Identities = 60/242 (24%), Positives = 89/242 (36%), Gaps = 68/242 (28%) Query: 16 LEGGKKAGSRTASPGAPGAHSHGLDL---GVPGSGDGKSESGFTDPEGFSFESESELIEQ 72 L+G K PG PG H ++ GVPG + G P+G Sbjct: 2636 LDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDR---------- 2685 Query: 73 GRVVLWGREGRPGTPVDDQGD--------VVDYSFYLADEPAAIVP-PPSVQGHPFPEGA 123 G +G+PG P DQG+ + + ++ +A P PP G PEG Sbjct: 2686 ------GFDGQPG-PKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGL 2738 Query: 124 AAEGSAENWADAEVGPSGRDVLGHSPG----KWQQASAGRLHLCGPGPVRAWKNPERGSK 179 + E GP G V+G +PG ++ GR PGP RG K Sbjct: 2739 QGQ-------KGERGPPGERVVG-APGVPGAPGERGEQGR-----PGPA-----GPRGEK 2780 Query: 180 SRWSLRVDP------QQPS----------AKGPTRLPTHDSDSA-DESSDLPLMKVGICR 222 +L D Q+ S A G LP++ +D+A + +P+++V Sbjct: 2781 GEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYAADTAGSQLHAVPVLRVSHAE 2840 Query: 223 NE 224 E Sbjct: 2841 EE 2842 Score = 34.7 bits (78), Expect = 0.21 Identities = 121/491 (24%), Positives = 150/491 (30%), Gaps = 93/491 (18%) Query: 13 GFDLEGGKKAGSRTASPGAP-GAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIE 71 G D G A P P GA D G G + E G P G + E Sbjct: 1776 GLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP-GLPGKPGE 1834 Query: 72 QGRVVLWGREGRPGTPVDD-----QGDVVDYSFYLADEP------AAIVPPPSVQGHPFP 120 G+ L G+ G PG P +D +GD D P I+ P G P P Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP 1894 Query: 121 EGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKS 180 G +G GP G G + K +Q G L G E GS Sbjct: 1895 VGPPGQGFP--GVPGGTGPKGD--RGETGSKGEQGLPGERGLRG----------EPGSVP 1940 Query: 181 RWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTS 240 ++ A + +S+ +P + G + G Q PG Sbjct: 1941 NVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPG--------- 1991 Query: 241 RQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSC 300 KE + PG RG P + E P P Sbjct: 1992 -------KEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGP---------------PGP 2029 Query: 301 SGAAAAGALP--QGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFS 358 SG A P GL R AGG G + RG GER P P Sbjct: 2030 SGLAGEPGKPGIPGLPGR--AGGVGEAGRPGERG-ERG--EKGERGEQGRDGPPGLPGTP 2084 Query: 359 GVRPQGMSKKPQKPKHS--SPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416 G P G P PK S PG +G + A+ + N D+ P+ G+ Sbjct: 2085 G--PPG----PPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGD-----RGV 2133 Query: 417 PRLSVRRGEFS--SSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPER 474 P + RGE D N P LPG E P G P P G PP P Sbjct: 2134 PGIKGDRGEPGPRGQDGN---PGLPG--ERGMAGPEG-KPGLQGPRG-------PPGPVG 2180 Query: 475 QQQPPGAQGCP 485 PG G P Sbjct: 2181 GHGDPGPPGAP 2191 Score = 30.4 bits (67), Expect = 4.0 Identities = 67/271 (24%), Positives = 81/271 (29%), Gaps = 79/271 (29%) Query: 11 GAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELI 70 G DL G A PG G G PG + G P+GF + Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDP----- 2371 Query: 71 EQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAE 130 V + G G PG P +GD+ L P A P V G P G E Sbjct: 2372 ---GVGVPGSPGPPGPP-GVKGDL-----GLPGLPGA----PGVVGFPGQTGPRGE---- 2414 Query: 131 NWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQQ 190 + GPSG L PG+ PGP+ P Sbjct: 2415 ---MGQPGPSGERGLAGPPGREGI----------PGPLG-----------------PPGP 2444 Query: 191 PSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKES 250 P + GP D D LP G + + G P R + R Sbjct: 2445 PGSVGPPGASGLKGDKGDPGVGLP----------GPRGERGEPGIRGEDGR--------- 2485 Query: 251 YLPVPGRFLTSAPRGLT-PVAERPAVGELED 280 PG+ PRGLT P R GE D Sbjct: 2486 ----PGQ---EGPRGLTGPPGSRGERGEKGD 2509 Score = 30.4 bits (67), Expect = 4.0 Identities = 112/455 (24%), Positives = 139/455 (30%), Gaps = 89/455 (19%) Query: 28 SPGAPGAHSHGLDLGVPGSGDGKSESGF---TDPEGFSFESESELIEQGRVVLWGREGRP 84 SPG PG DLG+PG GF T P G E+G GREG P Sbjct: 2378 SPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRG-EMGQPGPSGERGLAGPPGREGIP 2436 Query: 85 GTPVDDQGDVVDYSFYLADEPAAIVPP-----------PSVQGHPFPEGAAAEGSAENWA 133 G P+ G P ++ PP P V G P P G E Sbjct: 2437 G-PLGPPG-----------PPGSVGPPGASGLKGDKGDPGV-GLPGPRGERGEPGIRG-E 2482 Query: 134 DAEVGPSGRDVLGHSPG-------KWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRV 186 D G G L PG K SAG G V RG+K R Sbjct: 2483 DGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERG 2542 Query: 187 DPQQPSAKGPTRLPTHDSDSADE-------SSDLPLMK-----------VGICRNEGSQA 228 KGP D + S+ LP ++ GI + GS Sbjct: 2543 PRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG 2602 Query: 229 KPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQS 288 K G P R + G PRGL ER G +K + Sbjct: 2603 KDGVPGIRGE----------------KGDVGFMGPRGLK--GERGVKGACGLDGEKGDKG 2644 Query: 289 RAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPA-------CG 341 A RP +G P G+ + A GK+ L G RGF G Sbjct: 2645 EA--GPPGRPGLAGHKGEMGEP-GVPGQSGAPGKEGLIGPKG---DRGFDGQPGPKGDQG 2698 Query: 342 ERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPA--GRKTRESQAAAREDNDP 399 E+ P FP SG G + P P P G+K R P Sbjct: 2699 EKGERGTPGIGGFPGPSG--NDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAP 2756 Query: 400 NRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIR 434 P + RPG +GE + ++ +IR Sbjct: 2757 GVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIR 2791 Score = 29.6 bits (65), Expect = 6.9 Identities = 52/212 (24%), Positives = 66/212 (31%), Gaps = 34/212 (16%) Query: 25 RTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWGREGRP 84 + +PG GA D G PG G P+G + + Q V L G +G Sbjct: 2255 KPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP--GQAVVGLPGAKGEK 2312 Query: 85 GTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGS-----AENWADAEVGP 139 G P GD+V EP A +G P P G E + D + G Sbjct: 2313 GAPGGLAGDLV-------GEPGA----KGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGA 2361 Query: 140 SGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRL 199 G PG S G PGP G K L P P A G Sbjct: 2362 PGPKGFKGDPGVGVPGSPG-----PPGP--------PGVKGDLGL---PGLPGAPGVVGF 2405 Query: 200 PTHDSDSADESSDLPLMKVGICRNEGSQAKPG 231 P + P + G+ G + PG Sbjct: 2406 PGQTGPRGEMGQPGPSGERGLAGPPGREGIPG 2437 >gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sapiens] Length = 735 Score = 50.1 bits (118), Expect = 5e-06 Identities = 64/239 (26%), Positives = 85/239 (35%), Gaps = 25/239 (10%) Query: 270 AERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGL---SRRKMAGGKKSLG 326 A+RP E PQ S+A + P S + A GA Q L SRR + GG K Sbjct: 33 AQRPEPSPPEPEPQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSSRRWVLGGAKP-- 90 Query: 327 GASQLALGRGFPACGERLSAA---------PPEPATFPPFSGVRPQGMSKKPQKPKHSSP 377 A +LG G P GE P PA PP G +P + P+ ++P Sbjct: 91 -AEDTSLGPGVPGTGEPAGEIWYNPIPEEDPRPPAPEPP--GPQPGSAESEGLAPQGAAP 147 Query: 378 GKKPAGRKTRESQAAAREDNDPNRDEVP--RAQLPTHRPGLPRLSVRRGEFSSSDPNIRA 435 P +S AR + + ++P R +L P R R S Sbjct: 148 ASPPTKASRTKSPGPARRLSIKMK-KLPELRRRLSLRGPRAGRERERAAPAGSVISRYHL 206 Query: 436 PQLPGTSEPSAYSPGGLVPRRHAPSGNQQP--PVHPPRP---ERQQQPPGAQGCPRCIW 489 G P+A G PR S P P PP P + P A+ P +W Sbjct: 207 DSSVGGPGPAAGPGGTRSPRAGYLSDGDSPERPAGPPSPTSFRPYEVGPAARAPPAALW 265 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 50.1 bits (118), Expect = 5e-06 Identities = 64/302 (21%), Positives = 109/302 (36%), Gaps = 27/302 (8%) Query: 173 NPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGS 232 +P+ K+ S P R P+ + S+ S P MK G+ R +++ GS Sbjct: 1387 SPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASS---PEMKDGLPRTPSRRSRSGS 1443 Query: 233 PKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWG 292 D S S H P + RG + P L +P+ + +S + Sbjct: 1444 SPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSP 1503 Query: 293 KVE---VRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPP 349 ++ + P + + ++ Q R G + G + +L + + SA+P Sbjct: 1504 ELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV---------KPSASPQ 1554 Query: 350 EPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQL 409 E + S + ++ P + + S K+R S +R + P + PRA Sbjct: 1555 ERSESD--SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA- 1611 Query: 410 PTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHP 469 PR + G SS +P AP+ S S G P S + P HP Sbjct: 1612 -------PR--AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662 Query: 470 PR 471 P+ Sbjct: 1663 PK 1664 Score = 42.7 bits (99), Expect = 8e-04 Identities = 80/344 (23%), Positives = 122/344 (35%), Gaps = 39/344 (11%) Query: 120 PEGAAAEGSAENWADAEVGPSGRDVLGHSPGKW---QQASAGRLHL-CGPGPVRAWKNPE 175 P + GS+ D PS + G SPG + S GR P P + P Sbjct: 1435 PSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPR 1494 Query: 176 RGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSD---LPLMKVGICRNEGS----QA 228 S+S P P P + ++ S D + +G GS Sbjct: 1495 PRSRS-------PSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547 Query: 229 KP-GSPKKRADTSRQASFHCKESYLPVPGRFLT-SAPRGLTPVAERPAVGELEDSPQKKM 286 KP SP++R+++ K + P+ R + S+P + P SP+ K Sbjct: 1548 KPSASPQERSESDSSPDSKAK-TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606 Query: 287 QSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSA 346 + RA + + S A A P+ L RR +G GRG G + Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPA-PRALPRRSRSGSSSK---------GRGPSPEGSSSTE 1656 Query: 347 APPEPATFPPFSGVRPQGMSKKPQ-KPKHSSPGKKPAGRK----TRESQAAAREDNDPNR 401 + PE PP S +G P+ K K +P ++ + R TR+++ + R + + Sbjct: 1657 SSPE---HPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSS 1713 Query: 402 DEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPS 445 E P HR S E S S R+ P T S Sbjct: 1714 PETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS 1757 Score = 36.6 bits (83), Expect = 0.056 Identities = 70/311 (22%), Positives = 105/311 (33%), Gaps = 39/311 (12%) Query: 187 DPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFH 246 + +QP+ + P S+ S K ++ G +++ SP++ S + H Sbjct: 159 EAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKH 218 Query: 247 CKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAA-A 305 ES R TP ++R + +D +K+ +S R S +A + Sbjct: 219 RSES------ESKKRKHRSPTPKSKRKS----KDKKRKRSRSTTPAPKSRRAHRSTSADS 268 Query: 306 AGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPP--EPATFPPFSGVRPQ 363 A + SR + A K + LA PA G R P EP T P+ Sbjct: 269 ASSSDTSRSRSRSAAAKTH---TTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPE 325 Query: 364 GMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRD------------------EVP 405 +K+P P K TR S + R P P Sbjct: 326 TATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTP 385 Query: 406 RAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQP 465 +Q P + P S R P + PQ +SE S SP RHA S + P Sbjct: 386 LSQEPVNPPS--EASPTRDRSPPKSPE-KLPQ-SSSSESSPPSPQPTKVSRHASSSPESP 441 Query: 466 -PVHPPRPERQ 475 P P R+ Sbjct: 442 KPAPAPGSHRE 452 Score = 36.2 bits (82), Expect = 0.073 Identities = 70/326 (21%), Positives = 119/326 (36%), Gaps = 76/326 (23%) Query: 167 PVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGS 226 P R ++ R + +R S R + P+ +G +R T S L++ G + Sbjct: 663 PARRGRSRSR-TPARRSGRSRSRTPARRGRSRSRT---PRRGRSRSRSLVRRGRSHSRTP 718 Query: 227 Q--AKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQK 284 Q + GS +R + SR + + + P + S+ R + SP+ Sbjct: 719 QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL-----------SSPRS 767 Query: 285 KMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERL 344 K +SR + +R S SG++ ++ ++S G+SQ P R Sbjct: 768 KAKSR----LSLRRSLSGSSPCP------KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRS 817 Query: 345 SAAPPEPATFPPFSGVRPQGMSKKPQKPKHSSPGKKP---AGRKTRESQAAAREDNDPNR 401 S++PP P+ SK P + HSS P +G R+ + + N+ + Sbjct: 818 SSSPP------------PKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANE--Q 863 Query: 402 DEVPRAQLPTHRPGLPRLSVRRGEFSSS-DPNIRAPQLPGTSEPSAYSPGGLVPRRHAPS 460 P+ RR F SS DP +++ P RH+ S Sbjct: 864 SVTPQ---------------RRSCFESSPDPELKSR----------------TPSRHSCS 892 Query: 461 GNQQPPVHPPRPERQQQPPGAQGCPR 486 G+ P V P RQ + P+ Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSPQPK 918 Score = 35.4 bits (80), Expect = 0.13 Identities = 100/476 (21%), Positives = 154/476 (32%), Gaps = 58/476 (12%) Query: 20 KKAGSRTASPGAPGAHSHGLDLGVPGSGDGKSESGFTDPEGFSFESESELIEQGRVVLWG 79 K+ SR+ +P +H S S S S S + L G Sbjct: 244 KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS----------RSRSAAAKTHTTALAG 293 Query: 80 REGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGP 139 R P + +GD P + S Q PE A + S+ + D + Sbjct: 294 RSPSPASGRRGEGDA----------PFSEPGTTSTQRPSSPETATKQPSSP-YEDKDKDK 342 Query: 140 SGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDP--QQPSAKGPT 197 + SP +++S G P P+ A ER S L P Q+P Sbjct: 343 KEKSATRPSPSP-ERSSTGP-EPPAPTPLLA----ERHGGSPQPLATTPLSQEPVNPPSE 396 Query: 198 RLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPG- 256 PT D LP ++ S++ P SP+ + +S P PG Sbjct: 397 ASPTRDRSPPKSPEKLP-------QSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449 Query: 257 -RFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALP--QGL 313 R ++S+P R D SR G+ + + P +G Sbjct: 450 HREISSSPTSKNRSHGRAK----RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGH 505 Query: 314 SRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPK 373 SR + ++S S GR S +P P + + +G S+ ++ + Sbjct: 506 SRSRSPQWRRS---RSAQRWGRSRSPQRRGRSRSPQRPG-WSRSRNTQRRGRSRSARRGR 561 Query: 374 HSSPGKKPAGRKTRESQAAAREDNDPNRDEV---PRAQLPTHRPGLPRLSVRRGEFSSSD 430 S + PA R S+ AR +R R++ PT R R RRG S Sbjct: 562 SHS--RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT 619 Query: 431 PNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQGCPR 486 P R + T P P R + + P R + + P +G R Sbjct: 620 PARRRSR---TRSPVRRRSRSRSPARRSGRSRSRTPAR--RGRSRSRTPARRGRSR 670 Score = 32.0 bits (71), Expect = 1.4 Identities = 70/292 (23%), Positives = 103/292 (35%), Gaps = 64/292 (21%) Query: 189 QQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCK 248 QQPSA + P + S+ SS + S + S + +S +S + Sbjct: 2516 QQPSALAALQ-PAKERRSSSSSSS----------SSSSSSSSSSSSSSSSSSGSSSSDSE 2564 Query: 249 ESYLPVPGRFLTSAPRGLTPVAERPAVGE---LEDSPQKKMQSRAWGKVEVRPSCSGAAA 305 S LPV TP A + AV E E +P K+ + R S S +++ Sbjct: 2565 GSSLPVQPEVALKRVPSPTP-APKEAVREGRPPEPTPAKRKR---------RSSSSSSSS 2614 Query: 306 AGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGM 365 + + S + S +S + S++ P PA PQ + Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSS---------SSSSSSSSSSPSPAK------PGPQAL 2659 Query: 366 SKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT-HRPGLPRLSVRRG 424 PK +SP K P G + S R+ D RD + P R P+ S R Sbjct: 2660 ------PKPASPKKPPPGERRSRS---PRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQ 2710 Query: 425 EFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476 + SSS+ R Q + PS RR PS PRP R + Sbjct: 2711 QSSSSERGSRRGQRGDSRSPSHKR------RRETPS---------PRPMRHR 2747 Score = 31.2 bits (69), Expect = 2.4 Identities = 84/382 (21%), Positives = 135/382 (35%), Gaps = 52/382 (13%) Query: 122 GAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSR 181 G + EGS+ + E P R S + + R P + +PE K+R Sbjct: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTP---PRRRSSRSSPELTRKAR 1702 Query: 182 WSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSR 241 S R S + +R P S SS P K R S + P + TSR Sbjct: 1703 LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSP----RTKTTSR 1758 Query: 242 QASFHCKESYLPVPGRFLTSAPRGL------------TPVAERPAVGELEDSPQKKMQSR 289 + GR + PRGL R G + + +++ +SR Sbjct: 1759 R-------------GRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR 1805 Query: 290 AWGKV-EVRPSCSGAAAAGALPQGLSR---RKMAGGKKSLGGASQLALGRGFPACGERLS 345 + +V R SG + Q SR R+ G ++ + + + R PA +R S Sbjct: 1806 SRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKR-S 1864 Query: 346 AAPPEPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVP 405 + PAT S R +S++ + + S ++ + +T ++ +R P Sbjct: 1865 RSRASPATHRR-SRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS 1923 Query: 406 RAQLP--THRPGLPRLSVRRGEFSSSDPNI-------RAPQLPGTSEPSAYSPGGLVPRR 456 R++ P T R R R S P + R P + S SP + RR Sbjct: 1924 RSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSP---ITRR 1980 Query: 457 HAPSGNQQPPVHPPRPERQQQP 478 S ++ PV R + P Sbjct: 1981 R--SRSRTSPVTRRRSRSRTSP 2000 Score = 30.8 bits (68), Expect = 3.1 Identities = 26/110 (23%), Positives = 44/110 (40%), Gaps = 5/110 (4%) Query: 313 LSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKP 372 L+ +K + + G + G F A P P P+S VR S+ P Sbjct: 127 LNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPK 186 Query: 373 KHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT----HRPGLPR 418 + KK GR++ ES + RE ++ + R++ + HR P+ Sbjct: 187 QKKKKKKKDRGRRS-ESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPK 235 >gi|20070376 solute carrier family 38, member 10 isoform b [Homo sapiens] Length = 780 Score = 49.7 bits (117), Expect = 6e-06 Identities = 88/361 (24%), Positives = 130/361 (36%), Gaps = 45/361 (12%) Query: 135 AEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQQPSAK 194 AE P GR LG + G + +A L PV A R R + +Q K Sbjct: 406 AEEAPGGR--LGEAEGLMKVEAA---RLSAQDPVVAVAEDGREKPKLPKEREELEQAQIK 460 Query: 195 GPTRLP-THDSDSADESSDL--PLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESY 251 GP +P D A E + L P + + E + +P P + E Sbjct: 461 GPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEEN 520 Query: 252 LPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAA-AGALP 310 P P R G P + L DS ++K + G+V RP + A AG LP Sbjct: 521 KP-PSRHAG----GKAPGVQGQMAPPLPDSEREKQEPEQ-GEVGKRPGQAQALEEAGDLP 574 Query: 311 QGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQ 370 + + A G+ ++ A + P + P RPQ + + Q Sbjct: 575 EDPQKVPEADGQPAVQPAKE--------------DLGPGDRGLHP-----RPQAVLSEQQ 615 Query: 371 KPKHSSPGKK-----PAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGE 425 G+K P G ++ A + + + +P A+ P PGLP + + Sbjct: 616 NGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLP-AEKPAPGPGLPPEPREQRD 674 Query: 426 FSSSDPNIRAPQLPGTS---EPSAYSPGGLVPRRHAPSGNQQPPV-HPPRPERQQQPPGA 481 + N A QL G + +P A PG P P G+ Q + P RP QPP Sbjct: 675 VERAGGNQAASQLEGKASALQPPASGPGSGSPLPQ-PWGDAQVILGSPARPPFSFQPPAE 733 Query: 482 Q 482 Q Sbjct: 734 Q 734 >gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo sapiens] Length = 247 Score = 49.7 bits (117), Expect = 6e-06 Identities = 48/185 (25%), Positives = 65/185 (35%), Gaps = 14/185 (7%) Query: 310 PQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKP 369 P+G R+ GG + +G P G S PP P P G PQG ++ Sbjct: 36 PEG---RRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKP--EGRPPQGGNQSQ 90 Query: 370 QKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSS 429 P H ++P + +SQ P R P+ +HRP P R Sbjct: 91 GPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPP-PQGGNQSHRPPPPPGKPERPPPQGG 149 Query: 430 DPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVH--------PPRPERQQQPPGA 481 + + P PG E G +P G Q P PP P + Q PP A Sbjct: 150 NQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPA 209 Query: 482 QGCPR 486 G P+ Sbjct: 210 GGNPQ 214 Score = 43.9 bits (102), Expect = 4e-04 Identities = 47/175 (26%), Positives = 59/175 (33%), Gaps = 16/175 (9%) Query: 320 GGKKSLGGASQLALGRGFPACGERLSAAPP----EPATFPPFSGVRPQGMSKKPQKPKHS 375 GG +S G G P G S PP +P PP G + QG P KP+ Sbjct: 64 GGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERP 123 Query: 376 SPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPR----LSVRRGEFSSSDP 431 P G ++ + P ++Q P PG P + + S P Sbjct: 124 PP---QGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPP 180 Query: 432 NIRAPQLPGTSE---PSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQG 483 PQ P E P P G GN Q P PP + Q PP QG Sbjct: 181 G--KPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQG 233 Score = 43.9 bits (102), Expect = 4e-04 Identities = 55/200 (27%), Positives = 72/200 (36%), Gaps = 41/200 (20%) Query: 292 GKVEVRPSCSGAAAAGALPQG--LSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPP 349 GK E RP G + G P R GG +S G P G S PP Sbjct: 76 GKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPP 135 Query: 350 ----EPATFPPFSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVP 405 +P PP G + QG P KP+ P + G K+R +++ + P + E Sbjct: 136 PPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQE---GNKSRSARSPPGKPQGPPQQEGN 192 Query: 406 RAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQP 465 + Q P PG P+ G N + PQ P P+G Q Sbjct: 193 KPQGPPP-PGKPQGPPPAGG------NPQQPQAP-------------------PAGKPQG 226 Query: 466 PV------HPPRPERQQQPP 479 P PPRP + QQPP Sbjct: 227 PPPPPQGGRPPRPAQGQQPP 246 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 49.3 bits (116), Expect = 8e-06 Identities = 79/340 (23%), Positives = 120/340 (35%), Gaps = 51/340 (15%) Query: 164 GPG--PVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGIC 221 GPG P++ P+ S S+ ++ Q P P + PT + + + LPL + Sbjct: 224 GPGRDPLQQDGTPKSIS-SQQPEKIKSQPPGTGKPIQGPTQTPQT--DHAKLPLQR---- 276 Query: 222 RNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDS 281 ++P + K+AD R S + LP P + P P A++P + + Sbjct: 277 ----DASRPQT--KQADIVRGESV---KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPG 327 Query: 282 PQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACG 341 P K ++ G + G P G ++ + LG A A G Sbjct: 328 PAKP-PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA----QPLGPAKPPAQQTG----S 378 Query: 342 ERLSAAPPEPATF--PPFSGVRPQ---GMSKKP-----------QKPKHSSPGKKPAGRK 385 E+ S+ P P PP G P G +K P Q+P SP K P K Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438 Query: 386 TRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPS 445 T Q P ++P Q + + + P PQ PG ++P Sbjct: 439 TPVQQ--------PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP 490 Query: 446 AYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485 PG P P + PP P + Q PG+ P Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530 Score = 30.8 bits (68), Expect = 3.1 Identities = 34/141 (24%), Positives = 52/141 (36%), Gaps = 27/141 (19%) Query: 349 PEPATFPPFSGVRPQGMSKKPQKPKHSSP-GKKPAGRKTRESQAAAREDNDPNRDEVPRA 407 P PA PP +P PQ+P + P ++P K Q + P+ + Sbjct: 474 PGPAKPPP---QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK---PSPQQPGST 527 Query: 408 QLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPV 467 + P+ +PG + S Q P ++PSA P SG P+ Sbjct: 528 KPPSQQPGSAKPSA---------------QQPSPAKPSAQQ--STKPVSQTGSGK---PL 567 Query: 468 HPPRPERQQQPPGAQGCPRCI 488 PP + P +QG P+ I Sbjct: 568 QPPTVSPSAKQPPSQGLPKTI 588 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 49.3 bits (116), Expect = 8e-06 Identities = 79/340 (23%), Positives = 120/340 (35%), Gaps = 51/340 (15%) Query: 164 GPG--PVRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGIC 221 GPG P++ P+ S S+ ++ Q P P + PT + + + LPL + Sbjct: 224 GPGRDPLQQDGTPKSIS-SQQPEKIKSQPPGTGKPIQGPTQTPQT--DHAKLPLQR---- 276 Query: 222 RNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDS 281 ++P + K+AD R S + LP P + P P A++P + + Sbjct: 277 ----DASRPQT--KQADIVRGESV---KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPG 327 Query: 282 PQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACG 341 P K ++ G + G P G ++ + LG A A G Sbjct: 328 PAKP-PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA----QPLGPAKPPAQQTG----S 378 Query: 342 ERLSAAPPEPATF--PPFSGVRPQ---GMSKKP-----------QKPKHSSPGKKPAGRK 385 E+ S+ P P PP G P G +K P Q+P SP K P K Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438 Query: 386 TRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPS 445 T Q P ++P Q + + + P PQ PG ++P Sbjct: 439 TPVQQ--------PGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP 490 Query: 446 AYSPGGLVPRRHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485 PG P P + PP P + Q PG+ P Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530 Score = 30.8 bits (68), Expect = 3.1 Identities = 34/141 (24%), Positives = 52/141 (36%), Gaps = 27/141 (19%) Query: 349 PEPATFPPFSGVRPQGMSKKPQKPKHSSP-GKKPAGRKTRESQAAAREDNDPNRDEVPRA 407 P PA PP +P PQ+P + P ++P K Q + P+ + Sbjct: 474 PGPAKPPP---QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK---PSPQQPGST 527 Query: 408 QLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPV 467 + P+ +PG + S Q P ++PSA P SG P+ Sbjct: 528 KPPSQQPGSAKPSA---------------QQPSPAKPSAQQ--STKPVSQTGSGK---PL 567 Query: 468 HPPRPERQQQPPGAQGCPRCI 488 PP + P +QG P+ I Sbjct: 568 QPPTVSPSAKQPPSQGLPKTI 588 >gi|169160903 PREDICTED: hypothetical protein [Homo sapiens] Length = 426 Score = 48.1 bits (113), Expect = 2e-05 Identities = 97/406 (23%), Positives = 135/406 (33%), Gaps = 43/406 (10%) Query: 80 REGRPGTP-VDDQGDVVDYSFYLADEPAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVG 138 R PG P V Q + D P A PPP + P A E WA G Sbjct: 12 RTPAPGCPEVAPQPEGTDAPGPAVCSPTARAPPPILPAPQRPPTRAREWEGAAWAAGATG 71 Query: 139 PS-------GRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKN--PERGSKSRWSLRVDPQ 189 G LG P +++AS G PG RA + E G + R + + Sbjct: 72 VGAALLALPGSRRLGRVPLTFREASPGP----APGAPRARGSCGREPGPRRRRAPSSAGK 127 Query: 190 QPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKP--GSPKKRADTSRQASFHC 247 +P+A P S + + R+ GS +P G R R HC Sbjct: 128 RPAAAARAAPPRQRS-----------LARCLPRSVGSCVRPSVGPSLPRRHCRRHCRCHC 176 Query: 248 KESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAG 307 + LP P P P G S R + E P+ G Sbjct: 177 RRRPLPKPPPLQPRLGSASPPRLAAPLAGSRAPS-LSPFPRRCRRRAERSPAGHGL---- 231 Query: 308 ALPQGLSR-RKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMS 366 LP+ LSR ++ G ++ GG + GR C +PP PA P G + + Sbjct: 232 PLPRSLSRGGEVVGARRRRGGEERRVRGRR-QGCA---LGSPPIPAG-PAAPGRAGERRA 286 Query: 367 KKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEF 426 + + + PG P E R T + G P ++ Sbjct: 287 ARQWRKRGGGPGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGP 346 Query: 427 SSSDPNIRAPQLPG--TSEPSAYSPGGLVPRR-HAPSGNQQPPVHP 469 S P+ A ++PG T+ Y P L RR APS + P P Sbjct: 347 RLSAPSAEAEEVPGGHTASNPTYEP--LSSRRTKAPSEGRDSPSSP 390 >gi|239742467 PREDICTED: double homeobox, 4-like [Homo sapiens] Length = 483 Score = 48.1 bits (113), Expect = 2e-05 Identities = 97/413 (23%), Positives = 134/413 (32%), Gaps = 76/413 (18%) Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163 PA++ P PSV+ P A +++ AE GR W + + L C Sbjct: 44 PASLCPRPSVKFRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99 Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203 P P V+ W ER + R R P +GP Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159 Query: 204 SDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGR 257 + + L L GI E + G P+ R Q F + + P G Sbjct: 160 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRI----QIWFQNRRARHPGQGG 215 Query: 258 FLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRK 317 + GL A P G S + AWG P A GALPQG Sbjct: 216 RAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG----- 266 Query: 318 MAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSS- 376 A ++ A L + PA E +S P F + P G PQ P+ Sbjct: 267 -AFVSQAARAAPALQPSQAAPA--EGVSQPAPARGDFAYAAPAPPDGALSHPQAPRWPPH 323 Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAP 436 PGK +RED DP RD +P +PG + + P + Sbjct: 324 PGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQGQGV 359 Query: 437 QLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485 P TS+ S + G P+ P + PP P P+ + QG P Sbjct: 360 LAPPTSQGSPWWGWGRGPQVAGAAWEPQAGEAPPPQPAPPDASARQGQMQGIP 412 >gi|116089331 human immunodeficiency virus type I enhancer binding protein 3 [Homo sapiens] Length = 2406 Score = 47.4 bits (111), Expect = 3e-05 Identities = 93/385 (24%), Positives = 127/385 (32%), Gaps = 88/385 (22%) Query: 139 PSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPERGSKSRWSLRVDPQQPSAKGPTR 198 P+ R G + + A G+ L GPG +P G L +DP+ P Sbjct: 2068 PTRRWSPGQAESPPRSAPPGKWALAGPG------SPSAGEHGP-GLGLDPRVLFPPAP-- 2118 Query: 199 LPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFH------CKE--- 249 LP + E+ P K R+ P P S FH +E Sbjct: 2119 LPHKLLSRSPETCASPWQKAE-SRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIF 2177 Query: 250 SYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGAL 309 S+LP+ + LT AP L P+ V Q+R + P + A +G Sbjct: 2178 SHLPLHSQHLTRAPCPLIPIGGIQMV-----------QARPGAHPTLLPGPTAAWVSG-- 2224 Query: 310 PQGLSRRKMAGGKKSLGGASQLA-LGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKK 368 +GG L GA + GR P S +P + S G K Sbjct: 2225 --------FSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPK 2276 Query: 369 PQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRP-----GLPRLSVRR 423 ++ PG+ P D P+ P PTH P LPR R Sbjct: 2277 ERERTGGGPGRPP--------------DWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGR 2322 Query: 424 GEFSSSDPNIRAPQLPGTSEPSAYSP-------GGLV----------------PRRH--- 457 S P + +P+ P EPSA P G L PR Sbjct: 2323 RAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDS 2382 Query: 458 -APSGNQQPPVHPPRPERQQQPPGA 481 PSG+ +P HP +PE + PP A Sbjct: 2383 PKPSGSGEPRAHPHQPE-DRVPPNA 2406 >gi|239744249 PREDICTED: similar to double homeobox, 4 [Homo sapiens] Length = 483 Score = 47.0 bits (110), Expect = 4e-05 Identities = 97/413 (23%), Positives = 133/413 (32%), Gaps = 76/413 (18%) Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163 PA++ P PSV+ P A +++ AE GR W + + L C Sbjct: 44 PASLCPRPSVKLRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99 Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203 P P V+ W ER + R R P +GP Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159 Query: 204 SDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGR 257 + + L L GI E + G P+ R Q F + + P G Sbjct: 160 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRI----QIWFQNRRARHPGQGG 215 Query: 258 FLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRK 317 + GL A P G S + AWG P A GALPQG Sbjct: 216 RAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG----- 266 Query: 318 MAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSS- 376 A ++ A L + PA E +S P F + P G PQ P+ Sbjct: 267 -AFVSQAARAAPALQPSQAAPA--EGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPH 323 Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAP 436 PGK +RED DP RD +P +PG + + P + Sbjct: 324 PGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQGQGV 359 Query: 437 QLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485 P TS+ S + G P+ P PP P P+ + QG P Sbjct: 360 LAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASARQGQMQGIP 412 >gi|239744248 PREDICTED: similar to double homeobox, 4 [Homo sapiens] Length = 483 Score = 47.0 bits (110), Expect = 4e-05 Identities = 97/413 (23%), Positives = 133/413 (32%), Gaps = 76/413 (18%) Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163 PA++ P PSV+ P A +++ AE GR W + + L C Sbjct: 44 PASLCPRPSVKLRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99 Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203 P P V+ W ER + R R P +GP Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159 Query: 204 SDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGR 257 + + L L GI E + G P+ R Q F + + P G Sbjct: 160 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRI----QIWFQNRRARHPGQGG 215 Query: 258 FLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRK 317 + GL A P G S + AWG P A GALPQG Sbjct: 216 RAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG----- 266 Query: 318 MAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSS- 376 A ++ A L + PA E +S P F + P G PQ P+ Sbjct: 267 -AFVSQAARAAPALQPSQAAPA--EGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPH 323 Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAP 436 PGK +RED DP RD +P +PG + + P + Sbjct: 324 PGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQGQGV 359 Query: 437 QLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485 P TS+ S + G P+ P PP P P+ + QG P Sbjct: 360 LAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASARQGQMQGIP 412 >gi|239744244 PREDICTED: similar to double homeobox, 4 [Homo sapiens] Length = 483 Score = 47.0 bits (110), Expect = 4e-05 Identities = 100/417 (23%), Positives = 134/417 (32%), Gaps = 84/417 (20%) Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163 PA++ P PSV+ P A +++ AE GR W + + L C Sbjct: 44 PASLCPRPSVKLRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99 Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGP------- 196 P P V+ W ER + R R P +GP Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159 Query: 197 ---TRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKRADTSRQASFHCKESYLP 253 T T A E P GI E + G P+ R Q F + + P Sbjct: 160 TAVTGFQTALLLRAFEKDRFP----GIAAREELARETGLPESRI----QIWFQNRRARHP 211 Query: 254 VPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGL 313 G + GL A P G S + AWG P A GALPQG Sbjct: 212 GQGGRAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG- 266 Query: 314 SRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPK 373 A ++ A L + PA E +S P F + P G PQ P+ Sbjct: 267 -----AFVSQAARAAPALQPSQAAPA--EGISQPAPARGDFAYAAPAPPDGALSHPQAPR 319 Query: 374 HSS-PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPN 432 PGK +RED DP RD +P +PG + + P Sbjct: 320 WPPHPGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQ 355 Query: 433 IRAPQLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485 + P TS+ S + G P+ P PP P P+ + QG P Sbjct: 356 GQGVLAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASARQGQMQGIP 412 >gi|239744242 PREDICTED: similar to double homeobox, 4 [Homo sapiens] Length = 483 Score = 47.0 bits (110), Expect = 4e-05 Identities = 97/413 (23%), Positives = 133/413 (32%), Gaps = 76/413 (18%) Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163 PA++ P PSV+ P A +++ AE GR W + + L C Sbjct: 44 PASLCPRPSVKLRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99 Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203 P P V+ W ER + R R P +GP Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159 Query: 204 SDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGR 257 + + L L GI E + G P+ R Q F + + P G Sbjct: 160 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRI----QIWFQNRRARHPGQGG 215 Query: 258 FLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRK 317 + GL A P G S + AWG P A GALPQG Sbjct: 216 RAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG----- 266 Query: 318 MAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSS- 376 A ++ A L + PA E +S P F + P G PQ P+ Sbjct: 267 -AFVSQAARAAPALQPSQAAPA--EGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPH 323 Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAP 436 PGK +RED DP RD +P +PG + + P + Sbjct: 324 PGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQGQGV 359 Query: 437 QLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485 P TS+ S + G P+ P PP P P+ + QG P Sbjct: 360 LAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASARQGQMQGIP 412 >gi|239744240 PREDICTED: similar to double homeobox, 4 [Homo sapiens] Length = 483 Score = 47.0 bits (110), Expect = 4e-05 Identities = 97/413 (23%), Positives = 133/413 (32%), Gaps = 76/413 (18%) Query: 105 PAAIVPPPSVQGHPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLC- 163 PA++ P PSV+ P A +++ AE GR W + + L C Sbjct: 44 PASLCPRPSVKLRPGLTAMALPTPSDSTLPAEARGRGR----RRRLVWTPSQSEALRACF 99 Query: 164 --GPGP------------------VRAWKNPERGSKSRWSLRVDPQQPSAKGPTRLPTHD 203 P P V+ W ER + R R P +GP Sbjct: 100 ERNPYPGIATRERLAQAIGIPEPRVQIWFQNERSRQLRQHRRESRPWPGRRGPPEGRRKR 159 Query: 204 SDSADESSDLPLMKV------GICRNEGSQAKPGSPKKRADTSRQASFHCKESYLPVPGR 257 + + L L GI E + G P+ R Q F + + P G Sbjct: 160 TAVTGSQTALLLRAFEKDRFPGIAAREELARETGLPESRI----QIWFQNRRARHPGQGG 215 Query: 258 FLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEVRPSCSGAAAAGALPQGLSRRK 317 + GL A P G S + AWG P A GALPQG Sbjct: 216 RAPAQAGGLCSAA--PGGGHPAPSWVAFAHTGAWGTGLPAPHVP--CAPGALPQG----- 266 Query: 318 MAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPPFSGVRPQGMSKKPQKPKHSS- 376 A ++ A L + PA E +S P F + P G PQ P+ Sbjct: 267 -AFVSQAARAAPALQPSQAAPA--EGISQPAPARGDFAYAAPAPPDGALSHPQAPRWPPH 323 Query: 377 PGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAP 436 PGK +RED DP RD +P +PG + + P + Sbjct: 324 PGK-------------SREDRDPQRDGLP-GPCAVAQPGP----------AQAGPQGQGV 359 Query: 437 QLPGTSEPSAYSPGGLVPR----RHAPSGNQQPPVHPPRPERQQQPPGAQGCP 485 P TS+ S + G P+ P PP P P+ + QG P Sbjct: 360 LAPPTSQGSPWWGWGRGPQVAGAAWEPQAGAAPPPQPAPPDASARQGQMQGIP 412 >gi|54860105 nadrin isoform 2 [Homo sapiens] Length = 803 Score = 47.0 bits (110), Expect = 4e-05 Identities = 57/232 (24%), Positives = 87/232 (37%), Gaps = 43/232 (18%) Query: 293 KVEVRPSCSGAAAAGALPQGLSRRKMAGGK---KSLGGASQLALGRGFPACG-------- 341 K E P +A G + ++A G+ ++ G+ QL++G+ A G Sbjct: 494 KKESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRR 553 Query: 342 --ERLSAAPPEPATFPP-------FSGV--RPQGMSKKPQKPKHSSPGK---KPAGRKTR 387 ++ + APP+P PP SG P +S KP S P + +P G+ + Sbjct: 554 AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSA 613 Query: 388 ESQAAAREDNDPNRDEVPRAQLPTHRPGLPRLSVRRGEFSSSDPNIRAPQLP-------G 440 SQ +A + + Q P H P P+ + + PN + P P G Sbjct: 614 PSQLSAPRRYSSSLSPI---QAPNHPP--PQPPTQATPLMHTKPNSQGPPNPMALPSEHG 668 Query: 441 TSEPSAYSPGGLVPRRHAPSGNQQPPVHPPR------PERQQQPPGAQGCPR 486 +PS P P P G Q P + P+ PE Q G PR Sbjct: 669 LEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPR 720 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.132 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,898,529 Number of Sequences: 37866 Number of extensions: 1783927 Number of successful extensions: 10129 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 59 Number of HSP's successfully gapped in prelim test: 746 Number of HSP's that attempted gapping in prelim test: 7719 Number of HSP's gapped (non-prelim): 2573 length of query: 514 length of database: 18,247,518 effective HSP length: 107 effective length of query: 407 effective length of database: 14,195,856 effective search space: 5777713392 effective search space used: 5777713392 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.