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Search of human proteins with 223029442
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223029442 mothers against decapentaplegic homolog 3 isoform
3 [Homo sapiens]
(381 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3... 818 0.0
gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [... 763 0.0
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens] 700 0.0
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens] 700 0.0
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi... 700 0.0
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2... 680 0.0
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens] 488 e-138
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens] 488 e-138
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens] 488 e-138
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4... 487 e-138
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens] 484 e-137
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens] 484 e-137
gi|5174519 SMAD family member 9 isoform b [Homo sapiens] 479 e-135
gi|187828357 SMAD family member 9 isoform a [Homo sapiens] 472 e-133
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens] 205 6e-53
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens] 128 7e-30
gi|5174517 SMAD family member 7 [Homo sapiens] 115 7e-26
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens] 101 1e-21
gi|146134388 YLP motif containing 1 [Homo sapiens] 35 0.15
gi|239757414 PREDICTED: hypothetical protein XP_002345432 [Homo ... 34 0.25
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 33 0.56
gi|217416343 fibrosin-like 1 [Homo sapiens] 32 0.73
gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens] 32 0.95
gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens] 32 0.95
gi|157168329 formin 1 [Homo sapiens] 31 1.6
gi|154689780 son of sevenless homolog 2 [Homo sapiens] 31 1.6
gi|34452173 integrin alpha X precursor [Homo sapiens] 31 1.6
gi|75750531 ankyrin repeat and MYND domain containing 1 isoform ... 31 1.6
gi|58219024 hypothetical protein LOC352999 [Homo sapiens] 31 2.1
gi|11276067 snail 2 [Homo sapiens] 30 2.8
>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
[Homo sapiens]
Length = 381
Score = 818 bits (2113), Expect = 0.0
Identities = 381/381 (100%), Positives = 381/381 (100%)
Query: 1 MSCLHPRQTWKGAALVHRKAWWMGRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELR 60
MSCLHPRQTWKGAALVHRKAWWMGRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELR
Sbjct: 1 MSCLHPRQTWKGAALVHRKAWWMGRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELR 60
Query: 61 AMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENT 120
AMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENT
Sbjct: 61 AMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENT 120
Query: 121 NFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPV 180
NFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPV
Sbjct: 121 NFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPV 180
Query: 181 TYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVE 240
TYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVE
Sbjct: 181 TYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVE 240
Query: 241 LTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFN 300
LTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFN
Sbjct: 241 LTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFN 300
Query: 301 NQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPL 360
NQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPL
Sbjct: 301 NQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPL 360
Query: 361 QWLDKVLTQMGSPSIRCSSVS 381
QWLDKVLTQMGSPSIRCSSVS
Sbjct: 361 QWLDKVLTQMGSPSIRCSSVS 381
>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
[Homo sapiens]
Length = 425
Score = 763 bits (1971), Expect = 0.0
Identities = 359/366 (98%), Positives = 361/366 (98%)
Query: 16 VHRKAWWMGRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 75
V+ K + RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE
Sbjct: 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
Query: 76 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPET 135
VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPET
Sbjct: 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPET 179
Query: 136 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 195
PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE
Sbjct: 180 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 239
Query: 196 LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI 255
LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI
Sbjct: 240 LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI 299
Query: 256 GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG 315
GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG
Sbjct: 300 GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG 359
Query: 316 FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI 375
FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI
Sbjct: 360 FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI 419
Query: 376 RCSSVS 381
RCSSVS
Sbjct: 420 RCSSVS 425
>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
Length = 467
Score = 700 bits (1806), Expect = 0.0
Identities = 328/359 (91%), Positives = 344/359 (95%), Gaps = 2/359 (0%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQ
Sbjct: 109 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQ 168
Query: 85 RVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSE 143
RVETPVLPPVLVPRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SE
Sbjct: 169 RVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISE 228
Query: 144 DGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGE 202
DGETSD Q+N SMD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGE
Sbjct: 229 DGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGE 288
Query: 203 TFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAE 262
TFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAE
Sbjct: 289 TFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAE 348
Query: 263 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 322
CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL
Sbjct: 349 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 408
Query: 323 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct: 409 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
Length = 467
Score = 700 bits (1806), Expect = 0.0
Identities = 328/359 (91%), Positives = 344/359 (95%), Gaps = 2/359 (0%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQ
Sbjct: 109 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQ 168
Query: 85 RVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSE 143
RVETPVLPPVLVPRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SE
Sbjct: 169 RVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISE 228
Query: 144 DGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGE 202
DGETSD Q+N SMD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGE
Sbjct: 229 DGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGE 288
Query: 203 TFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAE 262
TFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAE
Sbjct: 289 TFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAE 348
Query: 263 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 322
CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL
Sbjct: 349 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 408
Query: 323 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct: 409 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
sapiens]
Length = 437
Score = 700 bits (1806), Expect = 0.0
Identities = 328/359 (91%), Positives = 344/359 (95%), Gaps = 2/359 (0%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQ
Sbjct: 79 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQ 138
Query: 85 RVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSE 143
RVETPVLPPVLVPRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SE
Sbjct: 139 RVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISE 198
Query: 144 DGETSDHQMNHSMDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGE 202
DGETSD Q+N SMD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGE
Sbjct: 199 DGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGE 258
Query: 203 TFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAE 262
TFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAE
Sbjct: 259 TFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAE 318
Query: 263 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 322
CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL
Sbjct: 319 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 378
Query: 323 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct: 379 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
[Homo sapiens]
Length = 320
Score = 680 bits (1755), Expect = 0.0
Identities = 320/320 (100%), Positives = 320/320 (100%)
Query: 62 MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 121
MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN
Sbjct: 1 MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 60
Query: 122 FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 181
FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT
Sbjct: 61 FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 120
Query: 182 YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL 241
YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL
Sbjct: 121 YCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVEL 180
Query: 242 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN 301
TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN
Sbjct: 181 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN 240
Query: 302 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 361
QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ
Sbjct: 241 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 300
Query: 362 WLDKVLTQMGSPSIRCSSVS 381
WLDKVLTQMGSPSIRCSSVS
Sbjct: 301 WLDKVLTQMGSPSIRCSSVS 320
>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 488 bits (1255), Expect = e-138
Identities = 244/399 (61%), Positives = 283/399 (70%), Gaps = 45/399 (11%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYHY+
Sbjct: 70 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYK 129
Query: 85 RVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQSNIP----- 133
RVE+PVLPPVLVPRH E + +F L +P+N FP +N P
Sbjct: 130 RVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSP 189
Query: 134 ------------------------------ETPPPGYLSEDGETSDHQMNHSMDAGSPNL 163
+TPPP Y+ D + + MD S N+
Sbjct: 190 NSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQPMDT-SNNM 247
Query: 164 SPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE 223
P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VDGFTDPSN++
Sbjct: 248 IPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNK 306
Query: 224 -RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGW 282
RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+
Sbjct: 307 SRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGF 366
Query: 283 HPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRR 342
HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFVKGWGAEY R
Sbjct: 367 HPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHR 426
Query: 343 QTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
Q VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 427 QDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 488 bits (1255), Expect = e-138
Identities = 244/399 (61%), Positives = 283/399 (70%), Gaps = 45/399 (11%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYHY+
Sbjct: 70 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYK 129
Query: 85 RVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQSNIP----- 133
RVE+PVLPPVLVPRH E + +F L +P+N FP +N P
Sbjct: 130 RVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSP 189
Query: 134 ------------------------------ETPPPGYLSEDGETSDHQMNHSMDAGSPNL 163
+TPPP Y+ D + + MD S N+
Sbjct: 190 NSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQPMDT-SNNM 247
Query: 164 SPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE 223
P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VDGFTDPSN++
Sbjct: 248 IPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNK 306
Query: 224 -RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGW 282
RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+
Sbjct: 307 SRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGF 366
Query: 283 HPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRR 342
HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFVKGWGAEY R
Sbjct: 367 HPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHR 426
Query: 343 QTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
Q VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 427 QDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 488 bits (1255), Expect = e-138
Identities = 244/399 (61%), Positives = 283/399 (70%), Gaps = 45/399 (11%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYHY+
Sbjct: 70 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYK 129
Query: 85 RVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQSNIP----- 133
RVE+PVLPPVLVPRH E + +F L +P+N FP +N P
Sbjct: 130 RVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSP 189
Query: 134 ------------------------------ETPPPGYLSEDGETSDHQMNHSMDAGSPNL 163
+TPPP Y+ D + + MD S N+
Sbjct: 190 NSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQPMDT-SNNM 247
Query: 164 SPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE 223
P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VDGFTDPSN++
Sbjct: 248 IPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNK 306
Query: 224 -RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGW 282
RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+
Sbjct: 307 SRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGF 366
Query: 283 HPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRR 342
HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFVKGWGAEY R
Sbjct: 367 HPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHR 426
Query: 343 QTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
Q VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 427 QDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
[Homo sapiens]
Length = 230
Score = 487 bits (1253), Expect = e-138
Identities = 230/230 (100%), Positives = 230/230 (100%)
Query: 152 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 211
MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM
Sbjct: 1 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 60
Query: 212 TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 271
TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV
Sbjct: 61 TVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 120
Query: 272 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 331
QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS
Sbjct: 121 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 180
Query: 332 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS
Sbjct: 181 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
Length = 465
Score = 484 bits (1246), Expect = e-137
Identities = 248/402 (61%), Positives = 282/402 (70%), Gaps = 50/402 (12%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ EVC+NPYHY+
Sbjct: 69 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYK 128
Query: 85 RVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE----------P 128
RVE+PVLPPVLVPRH+E + A+F L +P N FP + P
Sbjct: 129 RVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSP 188
Query: 129 QSNIP---------------------------ETPPPGYLS-EDGETSDHQMNHSMDAGS 160
S+ P +TPPP YL ED T D + MD
Sbjct: 189 NSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDG--SQPMDT-- 244
Query: 161 PNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPS 220
N+ P+ N D+Q V Y EP WCSI YYELN RVGE FHAS S+ VDGFTDPS
Sbjct: 245 -NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPS 303
Query: 221 NSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQR 279
N++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN
Sbjct: 304 NNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYH 363
Query: 280 YGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAE 339
+G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAE
Sbjct: 364 HGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAE 423
Query: 340 YRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
Y RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 424 YHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
Length = 465
Score = 484 bits (1246), Expect = e-137
Identities = 248/402 (61%), Positives = 282/402 (70%), Gaps = 50/402 (12%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ EVC+NPYHY+
Sbjct: 69 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYK 128
Query: 85 RVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE----------P 128
RVE+PVLPPVLVPRH+E + A+F L +P N FP + P
Sbjct: 129 RVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPNSHPFPHSP 188
Query: 129 QSNIP---------------------------ETPPPGYLS-EDGETSDHQMNHSMDAGS 160
S+ P +TPPP YL ED T D + MD
Sbjct: 189 NSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDG--SQPMDT-- 244
Query: 161 PNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPS 220
N+ P+ N D+Q V Y EP WCSI YYELN RVGE FHAS S+ VDGFTDPS
Sbjct: 245 -NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPS 303
Query: 221 NSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQR 279
N++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN
Sbjct: 304 NNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYH 363
Query: 280 YGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAE 339
+G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAE
Sbjct: 364 HGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAE 423
Query: 340 YRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
Y RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 424 YHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
Length = 430
Score = 479 bits (1232), Expect = e-135
Identities = 236/367 (64%), Positives = 279/367 (76%), Gaps = 19/367 (5%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ EVC+NPYHY+
Sbjct: 73 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYR 132
Query: 85 RVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIE--PQSNIPET 135
RVETPVLPPVLVPRH+E + L + HS +P N +P + P S +P +
Sbjct: 133 RVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPS 192
Query: 136 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 195
P + S ++ GSP+ P SP + + D +PV Y EP WCS++YYE
Sbjct: 193 PSHAF-----SQSPCTASYPHSPGSPS---EPESP-YQHSDFRPVCYEEPQHWCSVAYYE 243
Query: 196 LNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYY 254
LN RVGETF AS S+ +DGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY
Sbjct: 244 LNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYY 303
Query: 255 IGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQ 314
+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+
Sbjct: 304 VGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHH 363
Query: 315 GFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS 374
GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP
Sbjct: 364 GFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPH 423
Query: 375 IRCSSVS 381
SSVS
Sbjct: 424 NPISSVS 430
>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
Length = 467
Score = 472 bits (1214), Expect = e-133
Identities = 240/396 (60%), Positives = 283/396 (71%), Gaps = 40/396 (10%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ EVC+NPYHY+
Sbjct: 73 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYR 132
Query: 85 RVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIE--PQSNIPET 135
RVETPVLPPVLVPRH+E + L + HS +P N +P + P S +P +
Sbjct: 133 RVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPS 192
Query: 136 PP---------------PGYLSEDGETSDHQMN------HSMDAGSPNLSPNPMSPAHN- 173
P PG SE H ++ H+ +A S S P+ +
Sbjct: 193 PSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEA-SETQSGQPVDATADR 251
Query: 174 -------NLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RF 225
N D +PV Y EP WCS++YYELN RVGETF AS S+ +DGFTDPSN+ RF
Sbjct: 252 HVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRF 311
Query: 226 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPA 285
CLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPA
Sbjct: 312 CLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPA 371
Query: 286 TVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTV 345
TVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ V
Sbjct: 372 TVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDV 431
Query: 346 TSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
TSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 432 TSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
Length = 552
Score = 205 bits (521), Expect = 6e-53
Identities = 158/471 (33%), Positives = 209/471 (44%), Gaps = 128/471 (27%)
Query: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHH-----------ELRAMELCEFAFN--- 70
R+LDGRLQV+ RKG PHVIY RLWRWPDLH + +L+ +C ++
Sbjct: 76 RTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYER 135
Query: 71 ---------------------MKKDEVCVN--------------------PYHYQRVETP 89
M KDE + P + ET
Sbjct: 136 VVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETY 195
Query: 90 VLPPVLVPRHTEIP--AEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 147
P +L P + A FP + S S P + + E I P PG ++G T
Sbjct: 196 STPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQ-QQNGFT 254
Query: 148 SD--------------------------HQMNHSMDAGSPNLSPNPMS--PAHNNLDLQP 179
HQ H P + P+P P HN L QP
Sbjct: 255 GQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQH--HPPMPPHPGHYWPVHNELAFQP 312
Query: 180 VTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNR 235
PA +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R
Sbjct: 313 PISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHR 372
Query: 236 NAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPG 293
A+E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P
Sbjct: 373 TEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPS 432
Query: 294 CNLKIFN--------NQEFAALLAQSVNQGFE--------------------------AV 319
+K+F+ Q+ A A + Q V
Sbjct: 433 AYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGV 492
Query: 320 YQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 370
L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct: 493 DDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
Length = 496
Score = 128 bits (322), Expect = 7e-30
Identities = 101/332 (30%), Positives = 151/332 (45%), Gaps = 52/332 (15%)
Query: 31 LQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCE-FAFNMKKDEVCVNPYHYQRVETP 89
L++ + P ++ RL+RWPDL EL+ + C FA VC NPYH+ R+ P
Sbjct: 213 LRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGP 272
Query: 90 VLPPVLVPRHTEIPA--EFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 147
PP P ++ + E+ PLD + ++T E +++ P GE
Sbjct: 273 ESPP---PPYSRLSPRDEYKPLD-----LSDSTLSYTETEATNSLITAP--------GEF 316
Query: 148 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHAS 207
SD M SP+ P+H WCS++Y+E RVG +
Sbjct: 317 SDASM-----------SPDATKPSH---------------WCSVAYWEHRTRVGRLYAVY 350
Query: 208 QPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDS 267
++++ F D FCLG L+ R+ +V TR IG G+ L V+A +
Sbjct: 351 DQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEH 408
Query: 268 AIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCT 327
IFV SP + G V K+PPG ++K+F + E + L + Y +
Sbjct: 409 PIFVNSPTLDAP-GGRALVVRKVPPGYSIKVF-DFERSGLQHAPEPDAADGPYDPN---S 463
Query: 328 IRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 359
+R+SF KGWG Y RQ +TS PCW+E+ LN P
Sbjct: 464 VRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
>gi|5174517 SMAD family member 7 [Homo sapiens]
Length = 426
Score = 115 bits (288), Expect = 7e-26
Identities = 89/316 (28%), Positives = 148/316 (46%), Gaps = 48/316 (15%)
Query: 42 VIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTE 101
++ C+++RWPDL E++ + CE + + VC NP+H R+ PP P ++
Sbjct: 157 LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLCELESPP---PPYSR 213
Query: 102 IPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSP 161
P +F ++P ++ P+ P ET G+
Sbjct: 214 YPMDF-------------------LKPTADCPDAVP-----SSAET----------GGTN 239
Query: 162 NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN 221
L+P +S + L L+P + + WC ++Y+E RVG + +PS+ D F D
Sbjct: 240 YLAPGGLS--DSQLLLEP---GDRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQ 292
Query: 222 SERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYG 281
FCLG L++ N++ V+ R IG G++L V+ S IF++S +
Sbjct: 293 GNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS 352
Query: 282 WHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYR 341
V K+ PG ++K F+ ++ +L Q N E + Q T+++SFVKGWG Y
Sbjct: 353 -RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCYT 408
Query: 342 RQTVTSTPCWIELHLN 357
RQ ++S PCW+E+ N
Sbjct: 409 RQFISSCPCWLEVIFN 424
>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
Length = 235
Score = 101 bits (252), Expect = 1e-21
Identities = 74/235 (31%), Positives = 115/235 (48%), Gaps = 21/235 (8%)
Query: 134 ETPPPGY--LSEDGE-----TSDHQMNHSMDAGSPNL--SPNPMSPAHNNLDLQPVTYCE 184
++PPP Y LS E SD ++++ + +L +P S A + D +
Sbjct: 12 KSPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDAT-----K 66
Query: 185 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 244
P+ WCS++Y+E RVG + ++++ F D FCLG L+ R+ +V TR
Sbjct: 67 PSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRS 124
Query: 245 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 304
IG G+ L V+A + IFV SP + G V K+PPG ++K+F+ +
Sbjct: 125 KIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVFDFERS 183
Query: 305 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 359
A + + Y ++R+SF KGWG Y RQ +TS PCW+E+ LN P
Sbjct: 184 GLQHAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 234
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 34.7 bits (78), Expect = 0.15
Identities = 19/50 (38%), Positives = 22/50 (44%)
Query: 92 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYL 141
PP LVP E P E PP+ S+ P + P P S P T YL
Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYL 184
Score = 29.6 bits (65), Expect = 4.7
Identities = 23/103 (22%), Positives = 36/103 (34%), Gaps = 6/103 (5%)
Query: 84 QRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSE 143
Q++ + VL P H P PP + + P +P P P +
Sbjct: 65 QQMHQKQMQCVLQPHHLPPPPLPPP------PVMPGGGYGDWQPPPPPMPPPPGPALSYQ 118
Query: 144 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 186
+ HQM H G P L P + + + P +Y P+
Sbjct: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPS 161
>gi|239757414 PREDICTED: hypothetical protein XP_002345432 [Homo
sapiens]
Length = 176
Score = 33.9 bits (76), Expect = 0.25
Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 10/94 (10%)
Query: 77 CVNPYHYQRVETPVLPPVLVPR---HTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIP 133
C P+ +R T LPP L P H+ P P + P+ PA + PQ P
Sbjct: 75 CTQPHRRRRRGTRRLPPALTPAGPYHSARPGGGGPCQGSARFSPD----PAAVRPQ---P 127
Query: 134 ETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNP 167
P P S D + ++ G+P SP P
Sbjct: 128 RGPQPDSGSARQVPPDSRGAQALHRGAPLASPAP 161
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 32.7 bits (73), Expect = 0.56
Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 15/99 (15%)
Query: 87 ETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN--IPETPPPGYLSED 144
E P LPP +P T IP+ PP P ++ P +P+ +PE P G S
Sbjct: 1525 EPPGLPPASLPESTPIPSSSPP--------PLSSPLPEAPQPKEEPPVPEAPSSGPPSSS 1576
Query: 145 GE-----TSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQ 178
E T + S G +S + AHN L+
Sbjct: 1577 LELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQGLR 1615
>gi|217416343 fibrosin-like 1 [Homo sapiens]
Length = 1045
Score = 32.3 bits (72), Expect = 0.73
Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 13/103 (12%)
Query: 80 PYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS-------HSIPENTNFPAGIEPQSNI 132
P+ + P P L+P H +PA +S H + +++ P G+ ++
Sbjct: 294 PHRHTPQPPPPQPRGLLPTH--VPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSL 351
Query: 133 PETPPPGYLSEDG----ETSDHQMNHSMDAGSPNLSPNPMSPA 171
P +LS + HQ++ +M A P L P P PA
Sbjct: 352 SPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPA 394
>gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]
Length = 922
Score = 32.0 bits (71), Expect = 0.95
Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 13/90 (14%)
Query: 92 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 151
PP H +P PP ++ P N AG+ P +N+ PPP Y T +
Sbjct: 167 PPSTYNPHKPVPYPIPPCRPHATIAPSAYN-NAGLVPLANVIAPPPPPYTPNPVGTENED 225
Query: 152 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 181
++ NP P N P +
Sbjct: 226 LS------------NPSKPIQNQTFSTPAS 243
>gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]
Length = 944
Score = 32.0 bits (71), Expect = 0.95
Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 13/90 (14%)
Query: 92 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 151
PP H +P PP ++ P N AG+ P +N+ PPP Y T +
Sbjct: 189 PPSTYNPHKPVPYPIPPCRPHATIAPSAYN-NAGLVPLANVIAPPPPPYTPNPVGTENED 247
Query: 152 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 181
++ NP P N P +
Sbjct: 248 LS------------NPSKPIQNQTFSTPAS 265
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 31.2 bits (69), Expect = 1.6
Identities = 34/136 (25%), Positives = 45/136 (33%), Gaps = 24/136 (17%)
Query: 89 PVLPPVLVPRHTEIPAEFPPLDDYSHS-IPENTNFPAGIEPQSNIPETPPPGYLSEDGET 147
P PP L P + P PP +S P N P P + PPPG G +
Sbjct: 684 PPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSS 743
Query: 148 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHAS 207
S S P PA ++P +P +W I + +Q T
Sbjct: 744 S---------------SQCPRKPA-----IEPSCPMKPLYWTRIQISDRSQNATPTL--- 780
Query: 208 QPSMTVDGFTDPSNSE 223
S+ DPS E
Sbjct: 781 WDSLEEPDIRDPSEFE 796
>gi|154689780 son of sevenless homolog 2 [Homo sapiens]
Length = 1332
Score = 31.2 bits (69), Expect = 1.6
Identities = 24/93 (25%), Positives = 39/93 (41%), Gaps = 10/93 (10%)
Query: 92 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 151
PP + PR P P + + + + P P+ +P+TPPP L +H
Sbjct: 1172 PPAIPPRQPPPPKVKPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPL----RPPEHF 1227
Query: 152 MNHSMDAGSPNLSPNPMSPAHNNLD-LQPVTYC 183
+N NL P P+ H + D L+ ++ C
Sbjct: 1228 INCPF-----NLQPPPLGHLHRDSDWLRDISTC 1255
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 31.2 bits (69), Expect = 1.6
Identities = 13/39 (33%), Positives = 21/39 (53%)
Query: 341 RRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSS 379
+R S W+ + LN W+D ++ +PS+RCSS
Sbjct: 962 QRDLPVSINFWVPVELNQEAVWMDVEVSHPQNPSLRCSS 1000
>gi|75750531 ankyrin repeat and MYND domain containing 1 isoform 2
[Homo sapiens]
Length = 717
Score = 31.2 bits (69), Expect = 1.6
Identities = 36/150 (24%), Positives = 58/150 (38%), Gaps = 14/150 (9%)
Query: 21 WWMGRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMEL-CEFAFNMKKDE---- 75
W G S G +SHR+G +Y + R H H+++ + L C N DE
Sbjct: 131 WPDGSSFTGTFYLSHREGYG-TMYMKT-RLFQTHCHNDIVNLLLDCGADVNKCSDEGLTA 188
Query: 76 --VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIP----ENTNFPAGIEPQ 129
+C ++ + P + +P E P +FP + S S E+ + + Q
Sbjct: 189 LSMCFLLHYPAQSFKPNVAERTIPEPQE-PPKFPVVPILSSSFMDTNLESLYYEVNVPSQ 247
Query: 130 SNIPETPPPGYLSEDGETSDHQMNHSMDAG 159
+ PPP L + H+ H D G
Sbjct: 248 GSYELRPPPAPLLLPRVSGSHEGGHFQDTG 277
>gi|58219024 hypothetical protein LOC352999 [Homo sapiens]
Length = 330
Score = 30.8 bits (68), Expect = 2.1
Identities = 13/36 (36%), Positives = 22/36 (61%)
Query: 121 NFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSM 156
+F A + SN+ ET PP + G+ SD+++ +SM
Sbjct: 14 SFSASLAGTSNLSETEPPLWKESPGQLSDYRVENSM 49
>gi|11276067 snail 2 [Homo sapiens]
Length = 268
Score = 30.4 bits (67), Expect = 2.8
Identities = 23/103 (22%), Positives = 42/103 (40%), Gaps = 14/103 (13%)
Query: 76 VCVNPYHYQRVETPVLP-PVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPE 134
V ++PY Y+ PV+P P ++ + P+ ++ + P + P G+ P S
Sbjct: 27 VIISPYLYESYSMPVIPQPEILS-----SGAYSPITVWTTAAPFHAQLPNGLSPLSGYSS 81
Query: 135 -----TPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAH 172
+PPP D + DH + S + + +S H
Sbjct: 82 SLGRVSPPP---PSDTSSKDHSGSESPISDEEERLQSKLSDPH 121
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,922,401
Number of Sequences: 37866
Number of extensions: 950729
Number of successful extensions: 2529
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 2448
Number of HSP's gapped (non-prelim): 84
length of query: 381
length of database: 18,247,518
effective HSP length: 104
effective length of query: 277
effective length of database: 14,309,454
effective search space: 3963718758
effective search space used: 3963718758
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.