Search of human proteins with 223005950

Search of human proteins with 223005950

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
         (707 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                1439   0.0  
gi|46255026 potassium channel tetramerisation domain containing ...   844   0.0  
gi|169234778 potassium channel tetramerisation domain containing...    83   8e-16
gi|71143104 potassium channel tetramerisation domain containing ...    83   8e-16
gi|53829365 potassium channel tetramerisation domain containing ...    83   8e-16
gi|9506651 potassium channel tetramerisation domain containing 5...    74   4e-13
gi|23308551 potassium channel tetramerisation domain containing ...    72   2e-12
gi|189571693 potassium channel tetramerisation domain containing...    69   1e-11
gi|189571691 potassium channel tetramerisation domain containing...    69   1e-11
gi|146198864 potassium channel tetramerisation domain containing...    68   3e-11
gi|142356950 potassium channel tetramerisation domain containing...    65   2e-10
gi|194018443 potassium channel tetramerisation domain containing...    63   1e-09
gi|194018441 potassium channel tetramerisation domain containing...    63   1e-09
gi|194018439 potassium channel tetramerisation domain containing...    63   1e-09
gi|38198663 potassium channel tetramerisation domain containing ...    62   1e-09
gi|39753959 potassium channel tetramerisation domain containing ...    61   4e-09
gi|13994353 potassium channel tetramerisation domain containing ...    58   3e-08
gi|27436981 potassium voltage-gated channel, Shal-related subfam...    57   5e-08
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       57   5e-08
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       57   5e-08
gi|27436984 potassium voltage-gated channel, Shal-related subfam...    57   6e-08
gi|27436986 potassium voltage-gated channel, Shal-related subfam...    57   6e-08
gi|30578412 potassium channel tetramerisation domain containing ...    55   2e-07
gi|9789987 potassium voltage-gated channel, Shal-related subfami...    55   3e-07
gi|55926200 potassium channel tetramerisation domain containing ...    54   5e-07
gi|45387953 potassium channel tetramerization domain containing ...    53   8e-07
gi|19923973 potassium channel tetramerisation domain containing ...    53   8e-07
gi|218505694 potassium channel tetramerisation domain containing...    53   8e-07
gi|209969708 potassium channel tetramerisation domain containing...    53   8e-07
gi|40217617 potassium channel tetramerisation domain containing ...    53   8e-07

>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 1439 bits (3724), Expect = 0.0
 Identities = 707/707 (100%), Positives = 707/707 (100%)

Query: 1   MAAAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDET 60
           MAAAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDET
Sbjct: 1   MAAAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDET 60

Query: 61  GAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQLREELDRSS 120
           GAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQLREELDRSS
Sbjct: 61  GAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQLREELDRSS 120

Query: 121 CGNVLFNGYLPPPVFPVKRRNRHSLVGPQQLGGRPAPVRRSNTMPPNLGNAGLLGRMLDE 180
           CGNVLFNGYLPPPVFPVKRRNRHSLVGPQQLGGRPAPVRRSNTMPPNLGNAGLLGRMLDE
Sbjct: 121 CGNVLFNGYLPPPVFPVKRRNRHSLVGPQQLGGRPAPVRRSNTMPPNLGNAGLLGRMLDE 180

Query: 181 KTPPSPSGQPEEPGMVRLVCGHHNWIAVAYTQFLVCYRLKEASGWQLVFSSPRLDWPIER 240
           KTPPSPSGQPEEPGMVRLVCGHHNWIAVAYTQFLVCYRLKEASGWQLVFSSPRLDWPIER
Sbjct: 181 KTPPSPSGQPEEPGMVRLVCGHHNWIAVAYTQFLVCYRLKEASGWQLVFSSPRLDWPIER 240

Query: 241 LALTARVHGGALGEHDKMVAAATGSEILLWALQAEGGGSEIGVFHLGVPVEALFFVGNQL 300
           LALTARVHGGALGEHDKMVAAATGSEILLWALQAEGGGSEIGVFHLGVPVEALFFVGNQL
Sbjct: 241 LALTARVHGGALGEHDKMVAAATGSEILLWALQAEGGGSEIGVFHLGVPVEALFFVGNQL 300

Query: 301 IATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCNNGSIYYVDVQKFPLRMKD 360
           IATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCNNGSIYYVDVQKFPLRMKD
Sbjct: 301 IATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCNNGSIYYVDVQKFPLRMKD 360

Query: 361 NDLLVSELYRDPAEDGVTALSVYLTPKTSDSGNWIEIAYGTSSGGVRVIVQHPETVGSGP 420
           NDLLVSELYRDPAEDGVTALSVYLTPKTSDSGNWIEIAYGTSSGGVRVIVQHPETVGSGP
Sbjct: 361 NDLLVSELYRDPAEDGVTALSVYLTPKTSDSGNWIEIAYGTSSGGVRVIVQHPETVGSGP 420

Query: 421 QLFQTFTVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKIL 480
           QLFQTFTVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKIL
Sbjct: 421 QLFQTFTVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKIL 480

Query: 481 ALESADGHGGCSAGNDIGPYGERDDQQVFIQKVVPSASQLFVRLSSTGQRVCSVRSVDGS 540
           ALESADGHGGCSAGNDIGPYGERDDQQVFIQKVVPSASQLFVRLSSTGQRVCSVRSVDGS
Sbjct: 481 ALESADGHGGCSAGNDIGPYGERDDQQVFIQKVVPSASQLFVRLSSTGQRVCSVRSVDGS 540

Query: 541 PTTAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAMDGLGQAPAGGLTEQELME 600
           PTTAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAMDGLGQAPAGGLTEQELME
Sbjct: 541 PTTAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAMDGLGQAPAGGLTEQELME 600

Query: 601 QLEHCELAPPAPSAPSWGCLPSPSPRISLTSLHSASSNTSLSGHRGSPSPPQAEARRRGG 660
           QLEHCELAPPAPSAPSWGCLPSPSPRISLTSLHSASSNTSLSGHRGSPSPPQAEARRRGG
Sbjct: 601 QLEHCELAPPAPSAPSWGCLPSPSPRISLTSLHSASSNTSLSGHRGSPSPPQAEARRRGG 660

Query: 661 GSFVERCQELVRSGPDLRRPPTPAPWPSSGLGTPLTPPKMKLNETSF 707
           GSFVERCQELVRSGPDLRRPPTPAPWPSSGLGTPLTPPKMKLNETSF
Sbjct: 661 GSFVERCQELVRSGPDLRRPPTPAPWPSSGLGTPLTPPKMKLNETSF 707


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score =  844 bits (2180), Expect = 0.0
 Identities = 427/630 (67%), Positives = 494/630 (78%), Gaps = 22/630 (3%)

Query: 18  GEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILN 77
           GE++ LNVGG RFSTSRQTL WIPDSFFSSLLSGRISTL+DETGAIFIDRDP  FAPILN
Sbjct: 17  GEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILN 76

Query: 78  FLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQLREELDRSSCGNVLFNGYLPPPVFPV 137
           FLRTKELD RGV  + L HEA+FYG+TPLVRRL L EEL+RSSCG+VLF+GYLPPP  P 
Sbjct: 77  FLRTKELDLRGVSINVLRHEAEFYGITPLVRRLLLCEELERSSCGSVLFHGYLPPPGIPS 136

Query: 138 KRRNR--HSLVGPQQLGGRPAPVRRSNTMPPNLGNAGLLGRMLDEKTPPSPSGQPEEPGM 195
           ++ N    S      L       R + T P   G      R+          G P +P  
Sbjct: 137 RKINNTVRSADSRNGLNSTEGEARGNGTQPVLSGTGEETVRL----------GFPVDPRK 186

Query: 196 VRLVCGHHNWIAVAYTQFLVCYRLKEASGWQLVFSSPRLDWPIERLALTARVHGGALGEH 255
           V +V GHHNWI  AY  F VCYR+KE+SGWQ VF+SP LDW IER+AL A+V GG  G+ 
Sbjct: 187 VLIVAGHHNWIVAAYAHFAVCYRIKESSGWQQVFTSPYLDWTIERVALNAKVVGGPHGDK 246

Query: 256 DKMVAAATGSEILLWALQAEGGGSEIGVFHLGVPVEALFFVGNQLIATSHTGRIGVWNAV 315
           DKMVA A+ S I+LW++Q  G GSEIGVF LGVPV+ALFF+GNQL+ATSHTG++GVWNAV
Sbjct: 247 DKMVAVASESSIILWSVQDGGSGSEIGVFSLGVPVDALFFIGNQLVATSHTGKVGVWNAV 306

Query: 316 TKHWQVQEVQPITSYDAAGSFLLLGCNNGSIYYVDVQKFPLRMKDNDLLVSELYRDPAED 375
           T+HWQVQ+V PITSYD AGSFLLLGCNNGSIYY+D+QKFPLRMKDNDLLV+ELY DP+ D
Sbjct: 307 TQHWQVQDVVPITSYDTAGSFLLLGCNNGSIYYIDMQKFPLRMKDNDLLVTELYHDPSND 366

Query: 376 GVTALSVYLTPKTSDSGNWIEIAYGTSSGGVRVIVQHPETVGSGPQLFQTFTVHRSPVTK 435
            +TALSVYLTPKTS SGNWIEIAYGTSSG VRVIVQHPETVGSGPQLFQTFTVHRSPVTK
Sbjct: 367 AITALSVYLTPKTSVSGNWIEIAYGTSSGAVRVIVQHPETVGSGPQLFQTFTVHRSPVTK 426

Query: 436 IMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKILALESADGHGGCSAGN 495
           IMLSEKHL+SVCADNNHVRTW+VTRFRGMISTQPGSTPLASFKIL+LE  + HG  S+GN
Sbjct: 427 IMLSEKHLVSVCADNNHVRTWTVTRFRGMISTQPGSTPLASFKILSLEETESHGSYSSGN 486

Query: 496 DIGPYGERDDQQVFIQKVVPSASQLFVRLSSTGQRVCSVRSVDGSPTTAFTVLECEGSRR 555
           DIGP+GERDDQQVFIQKVVP  ++LFVRLSSTG+R+C +++VD +  ++FTV ECEGS R
Sbjct: 487 DIGPFGERDDQQVFIQKVVPITNKLFVRLSSTGKRICEIQAVDCTTISSFTVRECEGSSR 546

Query: 556 LGSRPRRYLLTGQANGSLAMWDLTTAMDGLGQA---PAGGLTEQELMEQLEHCELAPPAP 612
           +GSRPRRYL TG  NGS+ MWDLTTAMD + ++     GG TE+EL++ L+ C+L     
Sbjct: 547 MGSRPRRYLFTGHTNGSIQMWDLTTAMDMVNKSEDKDVGGPTEEELLKLLDQCDL----- 601

Query: 613 SAPSWGCLPSPSPRISLTS-LHSASSNTSL 641
            + S    P+ SP  S+    H   SN+SL
Sbjct: 602 -STSRCATPNISPATSVVQHSHLRESNSSL 630


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 83.2 bits (204), Expect = 8e-16
 Identities = 52/115 (45%), Positives = 68/115 (59%), Gaps = 2/115 (1%)

Query: 3   AAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGR-ISTLKDETG 61
           AA  A  G  + G  G+ + LNVGG  F T+RQTL     SF S L  G  + + +DETG
Sbjct: 15  AAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETG 74

Query: 62  AIFIDRDPTVFAPILNFLRTKELD-PRGVHGSSLLHEAQFYGLTPLVRRLQLREE 115
           A  IDRDPT F PILNFLR  +L   + +    +L EA+FY + PL+R ++ R E
Sbjct: 75  AYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRME 129


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 83.2 bits (204), Expect = 8e-16
 Identities = 52/124 (41%), Positives = 70/124 (56%), Gaps = 6/124 (4%)

Query: 21  IHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLR 80
           I LNVGGK ++TS  TLT  PDS   ++ SG++ T +D  G  FIDRD  VF  ILNFLR
Sbjct: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64

Query: 81  TKELD-PRGVHGSSLL-HEAQFYGLTPLVRRLQLRE----ELDRSSCGNVLFNGYLPPPV 134
           T  LD P       LL  EA FY + PL+  LQ +E    + ++++  N+  N  +    
Sbjct: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNITLNQRVQTVH 124

Query: 135 FPVK 138
           F V+
Sbjct: 125 FTVR 128


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 83.2 bits (204), Expect = 8e-16
 Identities = 61/141 (43%), Positives = 74/141 (52%), Gaps = 24/141 (17%)

Query: 3   AAATAAEGVPSRGPPGEV--------IHLNVGGKRFSTSRQTLTWIPDSFFSSLL---SG 51
           AAA A    P  GPP           + LNVGG  F T+RQTL   P SF   L      
Sbjct: 48  AAAVAQPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDP 107

Query: 52  RISTLKDETGAIFIDRDPTVFAPILNFLR------TKELDPRGVHGSSLLHEAQFYGLTP 105
            + + KDETGA  IDRDPT F PILN+LR      TKEL   GV     L EA+FY +  
Sbjct: 108 ELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGV-----LEEAEFYNIAS 162

Query: 106 LVR--RLQLREELDRSSCGNV 124
           LVR  + ++R+  +R+S G V
Sbjct: 163 LVRLVKERIRDNENRTSQGPV 183


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 50/117 (42%), Positives = 66/117 (56%), Gaps = 18/117 (15%)

Query: 17  PGEV---IHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGR--ISTLKDETGAIFIDRDPTV 71
           PG V   + LNVGG  F T+RQTL   P SF   L      + + KDETGA  IDRDPT 
Sbjct: 39  PGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTY 98

Query: 72  FAPILNFLR------TKELDPRGVHGSSLLHEAQFYGLTPLVRRL--QLREELDRSS 120
           F P+LN+LR       K+L   GV     L EA+FY +T L++ +  ++RE   ++S
Sbjct: 99  FGPVLNYLRHGKLVINKDLAEEGV-----LEEAEFYNITSLIKLVKDKIRERDSKTS 150


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 39/98 (39%), Positives = 57/98 (58%), Gaps = 1/98 (1%)

Query: 19  EVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNF 78
           EV+ LN+GG  F+T   TL    D+  +++ SGR     D  G  FIDRD T F  +LNF
Sbjct: 51  EVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNF 110

Query: 79  LRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQLREEL 116
           LR+ +L PR     ++  EAQ+Y + PL+ +L+  + L
Sbjct: 111 LRSGDLPPR-ERVRAVYKEAQYYAIGPLLEQLENMQPL 147


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 41/92 (44%), Positives = 52/92 (56%), Gaps = 2/92 (2%)

Query: 21  IHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLR 80
           + LNVGG  ++TS  TLT  PDS   ++  G   T +D  G  FIDRD  +F  +LNFLR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 81  TKELD-PRGVHGSSLLH-EAQFYGLTPLVRRL 110
           T EL  P       LL  EA FY + PL++ L
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 41/92 (44%), Positives = 52/92 (56%), Gaps = 2/92 (2%)

Query: 21  IHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLR 80
           + LNVGG  ++TS  TLT  PDS   ++  G   T +D  G  FIDRD  +F  +LNFLR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 81  TKELD-PRGVHGSSLLH-EAQFYGLTPLVRRL 110
           T EL  P       LL  EA FY + PL++ L
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 51/148 (34%), Positives = 72/148 (48%), Gaps = 15/148 (10%)

Query: 23  LNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLRTK 82
           LNVGG  + T +QTLT  PD+F   +++G+I    D  G  FIDRD  +F  +LNFLR  
Sbjct: 37  LNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLRNG 96

Query: 83  E-LDPRGVHGSSLL-HEAQFYGLTPLVRRLQLREELDRSSCGNVLF-------------N 127
           E L P G   + LL  EA+F+ L  L   ++ R E ++ +     F              
Sbjct: 97  ELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDNHDRSQGLR 156

Query: 128 GYLPPPVFPVKRRNRHSLVGPQQLGGRP 155
            +   P F  K ++R  LV   +L G P
Sbjct: 157 IFCNAPDFISKIKSRIVLVSKSRLDGFP 184


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 38/100 (38%), Positives = 53/100 (53%), Gaps = 2/100 (2%)

Query: 12  PSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTV 71
           P R     V+ LNVGG+  +T+  TL   P S  + + S       D  G  FIDR  T 
Sbjct: 26  PRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTY 85

Query: 72  FAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQ 111
           F PIL++LRT ++  +  H   +  EAQFY + PLV+ L+
Sbjct: 86  FRPILDYLRTGQVPTQ--HIPEVYREAQFYEIKPLVKLLE 123


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 14/115 (12%)

Query: 7   AAEGVP-------SRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDE 59
           AA+G+P       S  P    +H++VGG  +++S  TLT  PDS  S L +G    + D 
Sbjct: 41  AAQGIPLPAQLTKSNAP----VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDS 96

Query: 60  TGA-IFIDRDPTVFAPILNFLRT-KELDPRGVHGSSLLH-EAQFYGLTPLVRRLQ 111
                FIDRD  +F  +L+FLRT K L P      SLL+ EA++Y L P+VR L+
Sbjct: 97  LKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELE 151


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 14/115 (12%)

Query: 7   AAEGVP-------SRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDE 59
           AA+G+P       S  P    +H++VGG  +++S  TLT  PDS  S L +G    + D 
Sbjct: 41  AAQGIPLPAQLTKSNAP----VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDS 96

Query: 60  TGA-IFIDRDPTVFAPILNFLRT-KELDPRGVHGSSLLH-EAQFYGLTPLVRRLQ 111
                FIDRD  +F  +L+FLRT K L P      SLL+ EA++Y L P+VR L+
Sbjct: 97  LKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELE 151


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 14/115 (12%)

Query: 7   AAEGVP-------SRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDE 59
           AA+G+P       S  P    +H++VGG  +++S  TLT  PDS  S L +G    + D 
Sbjct: 41  AAQGIPLPAQLTKSNAP----VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDS 96

Query: 60  TGA-IFIDRDPTVFAPILNFLRT-KELDPRGVHGSSLLH-EAQFYGLTPLVRRLQ 111
                FIDRD  +F  +L+FLRT K L P      SLL+ EA++Y L P+VR L+
Sbjct: 97  LKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELE 151


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 43/119 (36%), Positives = 61/119 (51%), Gaps = 11/119 (9%)

Query: 3   AAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLS---------GRI 53
           A+A AA G  +  P  EV+ LNVGG+ + T   TL  +PDS  +S+ S          R 
Sbjct: 28  ASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRG 87

Query: 54  STLKDETGAIFIDRDPTVFAPILNFLRTKE--LDPRGVHGSSLLHEAQFYGLTPLVRRL 110
              +D     FIDRD  +F  +L++LR K+  L         LL EA+++ LT LV+ L
Sbjct: 88  ELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLL 146


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 37/94 (39%), Positives = 54/94 (57%), Gaps = 4/94 (4%)

Query: 23  LNVGGKRFSTSRQTLT-WIPDSFFSSLLS--GRISTLKDETGAIFIDRDPTVFAPILNFL 79
           LNVGG+ F+T+R TL    PDS  + +    G     +D  GA  IDR P  F PILN+L
Sbjct: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPILNYL 152

Query: 80  RTKELDPR-GVHGSSLLHEAQFYGLTPLVRRLQL 112
           R  +L    G++   +L EA+F+G+  L+  L++
Sbjct: 153 RHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEV 186


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 41/111 (36%), Positives = 53/111 (47%), Gaps = 3/111 (2%)

Query: 3   AAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGA 62
           AAAT         P  + + LNVGG  + T+ QTLT   D+   ++ SGR+  L D  G 
Sbjct: 16  AAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGW 74

Query: 63  IFIDRDPTVFAPILNFLR--TKELDPRGVHGSSLLHEAQFYGLTPLVRRLQ 111
           I IDR    F  ILN+LR     L         LL EA++Y +  LV   Q
Sbjct: 75  ILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQ 125


>gi|27436981 potassium voltage-gated channel, Shal-related
           subfamily, member 1 [Homo sapiens]
          Length = 647

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 44/108 (40%), Positives = 55/108 (50%), Gaps = 6/108 (5%)

Query: 13  SRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVF 72
           SRG   EV+ +NV G+RF T + TL   PD+   S  S +      ++G  F DRDP +F
Sbjct: 36  SRGD--EVLVVNVSGRRFETWKNTLDRYPDTLLGS--SEKEFFYDADSGEYFFDRDPDMF 91

Query: 73  APILNFLRTKELD-PRGVHGSSLLHEAQFYGLTP-LVRRLQLREELDR 118
             +LNF RT  L  PR     +   E  FYGL P LV    L E  DR
Sbjct: 92  RHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDR 139


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 38/91 (41%), Positives = 49/91 (53%), Gaps = 2/91 (2%)

Query: 19  EVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNF 78
           E++ LNVGGK F+T   T+   P S  + +L GR    K   G IF+DRD  +F+ IL+F
Sbjct: 5   ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDF 64

Query: 79  LRTKE--LDPRGVHGSSLLHEAQFYGLTPLV 107
           LRT +  L         L  EA FY L  LV
Sbjct: 65  LRTHQLLLPTEFSDYLRLQREALFYELRSLV 95


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 38/91 (41%), Positives = 49/91 (53%), Gaps = 2/91 (2%)

Query: 19  EVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNF 78
           E++ LNVGGK F+T   T+   P S  + +L GR    K   G IF+DRD  +F+ IL+F
Sbjct: 5   ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDF 64

Query: 79  LRTKE--LDPRGVHGSSLLHEAQFYGLTPLV 107
           LRT +  L         L  EA FY L  LV
Sbjct: 65  LRTHQLLLPTEFSDYLRLQREALFYELRSLV 95


>gi|27436984 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 1 [Homo sapiens]
          Length = 655

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 37/88 (42%), Positives = 48/88 (54%), Gaps = 3/88 (3%)

Query: 19  EVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNF 78
           E+I LNV G+RF T R TL   PD+   S  + +     ++T   F DRDP VF  +LNF
Sbjct: 40  ELIVLNVSGRRFQTWRTTLERYPDTLLGS--TEKEFFFNEDTKEYFFDRDPEVFRCVLNF 97

Query: 79  LRTKELD-PRGVHGSSLLHEAQFYGLTP 105
            RT +L  PR    S+   E  FYG+ P
Sbjct: 98  YRTGKLHYPRYECISAYDDELAFYGILP 125


>gi|27436986 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 2 [Homo sapiens]
          Length = 636

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 37/88 (42%), Positives = 48/88 (54%), Gaps = 3/88 (3%)

Query: 19  EVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNF 78
           E+I LNV G+RF T R TL   PD+   S  + +     ++T   F DRDP VF  +LNF
Sbjct: 40  ELIVLNVSGRRFQTWRTTLERYPDTLLGS--TEKEFFFNEDTKEYFFDRDPEVFRCVLNF 97

Query: 79  LRTKELD-PRGVHGSSLLHEAQFYGLTP 105
            RT +L  PR    S+   E  FYG+ P
Sbjct: 98  YRTGKLHYPRYECISAYDDELAFYGILP 125


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 41/123 (33%), Positives = 59/123 (47%), Gaps = 17/123 (13%)

Query: 7   AAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFID 66
           AA G+    P  + + LNVGG    T+ +TLT   D+   ++ SGR+  L D  G + ID
Sbjct: 29  AAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAGGWVLID 87

Query: 67  RDPTVFAPILNFLR---------TKELDPRGVHGSSLLHEAQFYGLTPLVRRLQLREELD 117
           R    F  ILN+LR         T+EL         LL EA++Y +  L+   QL  +  
Sbjct: 88  RSGRHFGTILNYLRDGSVPLPESTREL-------GELLGEARYYLVQGLIEDCQLALQQK 140

Query: 118 RSS 120
           R +
Sbjct: 141 RET 143


>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
           member 2 [Homo sapiens]
          Length = 630

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 38/87 (43%), Positives = 45/87 (51%), Gaps = 3/87 (3%)

Query: 20  VIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFL 79
           +I LNV G RF T + TL   PD+   S  S R      ET   F DRDP +F  ILNF 
Sbjct: 42  LIVLNVSGTRFQTWQDTLERYPDTLLGS--SERDFFYHPETQQYFFDRDPDIFRHILNFY 99

Query: 80  RTKELD-PRGVHGSSLLHEAQFYGLTP 105
           RT +L  PR    S+   E  F+GL P
Sbjct: 100 RTGKLHYPRHECISAYDEELAFFGLIP 126


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 8/106 (7%)

Query: 11  VPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRIST----LKDETGAIFID 66
           VP+  P  EV+ LNVGG+ + T   TL  IP S    + S +  T     KD  G  FID
Sbjct: 19  VPNSFP--EVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFID 76

Query: 67  RDPTVFAPILNFLRTKE--LDPRGVHGSSLLHEAQFYGLTPLVRRL 110
           RD  +F  IL++LR ++  L         L  EA+++ L  LV+ L
Sbjct: 77  RDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 1/86 (1%)

Query: 19  EVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNF 78
           +V+ LNVGG  ++  R++L    DS  +S+ SGR     DE+GA  IDRD  +F  +L++
Sbjct: 12  DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71

Query: 79  LRTKELDPRGVHGS-SLLHEAQFYGL 103
           L  +   P       +L  EA ++G+
Sbjct: 72  LHGEVQIPTDEQTRIALQEEADYFGI 97


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 58/211 (27%), Positives = 84/211 (39%), Gaps = 39/211 (18%)

Query: 3   AAATAAEGVPSRGPPG----------------EVIHLNVGGKRFSTSRQTLTWIPDSFFS 46
           A A +  G+P+ G  G                +++ LNVGG+ + T R T+  +PDS   
Sbjct: 2   ALADSTRGLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLW 61

Query: 47  SLLSGR--ISTLKDETGAIFIDRDPTVFAPILNFLRTKE--LDPRGVHGSSLLHEAQFYG 102
            + + +      +D  G  F+DRD  +F  IL++LR  +  L       S L  EA+++ 
Sbjct: 62  RMFTQQQPQELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFE 121

Query: 103 LTPLVRRLQLREELDRSSCGNVLFNGYLPPPVFPVKRRNRHSLVGPQQLGGRPAPVRRSN 162
           L  LVRRL   ++               P P  P  RR  H       LG    P+  S 
Sbjct: 122 LPELVRRLGAPQQ---------------PGPGPPPSRRGVHK---EGSLGDELLPLGYSE 163

Query: 163 TMPPNLGNAGLLGRMLDEKTPPSPSGQPEEP 193
                  +AG     L E    SPSG    P
Sbjct: 164 PEQQEGASAGAPSPTL-ELASRSPSGGAAGP 193


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 42/118 (35%), Positives = 63/118 (53%), Gaps = 8/118 (6%)

Query: 6   TAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGA-IF 64
           T A+   S  P    +H++VGG  +++S  TLT  P+S    L  G    + D      F
Sbjct: 629 TPAQLTKSNAP----VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYF 684

Query: 65  IDRDPTVFAPILNFLRT-KELDPRGVHGSSLLH-EAQFYGLTPLVRRLQLREELDRSS 120
           IDRD  +F  ILNFLRT K L P      +LL+ EA+++ L P++  ++ R + DR +
Sbjct: 685 IDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRET 741


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 42/118 (35%), Positives = 63/118 (53%), Gaps = 8/118 (6%)

Query: 6   TAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGA-IF 64
           T A+   S  P    +H++VGG  +++S  TLT  P+S    L  G    + D      F
Sbjct: 21  TPAQLTKSNAP----VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYF 76

Query: 65  IDRDPTVFAPILNFLRT-KELDPRGVHGSSLLH-EAQFYGLTPLVRRLQLREELDRSS 120
           IDRD  +F  ILNFLRT K L P      +LL+ EA+++ L P++  ++ R + DR +
Sbjct: 77  IDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRET 133


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 42/118 (35%), Positives = 63/118 (53%), Gaps = 8/118 (6%)

Query: 6   TAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGA-IF 64
           T A+   S  P    +H++VGG  +++S  TLT  P+S    L  G    + D      F
Sbjct: 21  TPAQLTKSNAP----VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYF 76

Query: 65  IDRDPTVFAPILNFLRT-KELDPRGVHGSSLLH-EAQFYGLTPLVRRLQLREELDRSS 120
           IDRD  +F  ILNFLRT K L P      +LL+ EA+++ L P++  ++ R + DR +
Sbjct: 77  IDRDGQMFRYILNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEME-RWKQDRET 133


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,143,954
Number of Sequences: 37866
Number of extensions: 1740353
Number of successful extensions: 7897
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 169
Number of HSP's that attempted gapping in prelim test: 7464
Number of HSP's gapped (non-prelim): 531
length of query: 707
length of database: 18,247,518
effective HSP length: 109
effective length of query: 598
effective length of database: 14,120,124
effective search space: 8443834152
effective search space used: 8443834152
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.