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Search of human proteins with 222446603
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
(668 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 1350 0.0
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 1229 0.0
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 1226 0.0
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 968 0.0
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 789 0.0
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 746 0.0
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 500 e-141
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 498 e-141
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 379 e-105
gi|239750781 PREDICTED: golgi autoantigen, golgin subfamily a-li... 323 2e-88
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 261 2e-69
gi|148746195 trichohyalin [Homo sapiens] 238 1e-62
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 233 3e-61
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 226 7e-59
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 223 6e-58
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 221 1e-57
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 220 3e-57
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 216 7e-56
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 213 4e-55
gi|221219020 NYD-SP11 protein [Homo sapiens] 183 5e-46
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 174 2e-43
gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 174 2e-43
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 172 7e-43
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 149 8e-36
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 148 1e-35
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l... 148 1e-35
gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-l... 148 2e-35
gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-l... 148 2e-35
gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-l... 148 2e-35
gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-l... 147 2e-35
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 1350 bits (3494), Expect = 0.0
Identities = 668/668 (100%), Positives = 668/668 (100%)
Query: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL
Sbjct: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
Query: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA
Sbjct: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
Query: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA
Sbjct: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI
Sbjct: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
Query: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
Query: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE
Sbjct: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 420
KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR
Sbjct: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 420
Query: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 480
QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ
Sbjct: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 480
Query: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR
Sbjct: 481 KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK 600
EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK 600
Query: 601 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660
IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH
Sbjct: 601 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660
Query: 661 QEHLEAAI 668
QEHLEAAI
Sbjct: 661 QEHLEAAI 668
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 1229 bits (3179), Expect = 0.0
Identities = 638/750 (85%), Positives = 650/750 (86%), Gaps = 90/750 (12%)
Query: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL
Sbjct: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
Query: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA
Sbjct: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
Query: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA
Sbjct: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI
Sbjct: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
Query: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
Query: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE
Sbjct: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 361 KEEKMRRLEEMMWEKEEK--------------IRELEEKMHEQEKIREQEEKRQEEEKIR 406
KEEKMRR EEMMWEKEEK IRELEEKMHEQEKIREQEEKRQEEEKIR
Sbjct: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 420
Query: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 466
EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 467 QEEKIREQEEIWRQKEKMHEQE-KIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE-- 523
QEEKI EQEEIWRQKEKMHEQE KIRKQEEKVWRQEEK+ +QEEKIREQEEKMWRQEE
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Query: 524 ---------------------------------------------------KIREQEEKI 532
KIREQEEK
Sbjct: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
Query: 533 RE-------QEEKIREQEEMMQEQEEKMGEQEEKMQEQ--------EKMRRQEEKIREQE 577
+E QEEKIREQEE +QEQEEK+ EQEEK++EQ EKM QEEK+ EQE
Sbjct: 601 QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660
Query: 578 EKIRE-------QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 630
EK++E Q+EKIREQE+KI EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 720
Query: 631 EQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660
EQEEKMRRQEEKMWEQEVRLRQQEEKMQEH
Sbjct: 721 EQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 296 bits (758), Expect = 4e-80
Identities = 205/547 (37%), Positives = 296/547 (54%), Gaps = 140/547 (25%)
Query: 245 KELKRKLERAKLLLPQQ-QLQAE---ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
+EL+ ++ ++L Q+ +LQ + H K+L+ + L +++ ++ + +Q
Sbjct: 123 RELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALS 182
Query: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE-EMMW 359
+ Q++K + E++ ++ + + + + +E+++ + + EK + + ++ E+
Sbjct: 183 AVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQL 242
Query: 360 EKEEKMRRLE--EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417
+E R+LE +++ +++ E + E + + + + + EE ++ + Q+QE K
Sbjct: 243 NVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR-LNQQQEEK 301
Query: 418 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE--------MWRQEE 469
MWRQEEKI+E EEKI+EQE+K+ QEEKI +EQEE MW +EE
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKI------------REQEEKMRRQEEMMWEKEE 349
Query: 470 KIREQEEIWRQK------------------------------------EKMHEQEKIRKQ 493
K+R QEE+ +K EKMHEQEKIR+Q
Sbjct: 350 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409
Query: 494 EE-------------------KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQE----- 529
EE K+WRQEEK+ +QEEKIREQE+KMWRQEEKI EQE
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Query: 530 --------------------------EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
EK+ EQEEKIR+QEE + QEEK+ EQEEK++EQ
Sbjct: 470 EKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529
Query: 564 -EKMRRQEEKIREQEEKIRE-------------------------QKEKIREQEEKIWEQ 597
EKM RQEEKIREQEE RE Q+EKIREQEEK+W Q
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ 589
Query: 598 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657
EEKIREQEE QEQEEKMW+QEEK+ EQEEK+QEQEEK+R QEEK+ EQE ++QEEKM
Sbjct: 590 EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 658 QEHQEHL 664
E +E +
Sbjct: 650 GEQEEKM 656
Score = 224 bits (570), Expect = 3e-58
Identities = 152/426 (35%), Positives = 235/426 (55%), Gaps = 95/426 (22%)
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRL---EEMMWEKEEKIRELEEKMHE 388
EQ+ + QE + E E ++ + +K E L + + + E + R+L ++H+
Sbjct: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 169
Query: 389 QEKIREQEE---------KRQEEEKIREQEKRQEQ-EAKMWRQ---EEKIREQEEKIREQ 435
K + E K++ + I E K ++ +++R +E+++E+ K+ Q
Sbjct: 170 SWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL--Q 227
Query: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR-EQEEIWRQKEKMHEQEKIRKQE 494
EK + EK Q ++E +++ E+ ++ +++++ E + + ++ + + + + + +E
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
Query: 495 EKVW-----RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ 549
++W +QEEKM QEEKI+E EEK+ QEEKIREQEEKIREQEEK+R QEEMM E+
Sbjct: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK 347
Query: 550 EEKMGEQEEKM---------------QEQEKMRRQEEKIREQEEKIRE------QKEKIR 588
EEKM QEE M +++EKMRRQEE + E+EEKIRE ++EKIR
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 407
Query: 589 EQEE-------------------KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQE--- 626
EQEE K+W QEEKIREQEE ++EQE+KMW QEEK+ EQE
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 467
Query: 627 ----------------------------EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
EKM EQEEK+R+QEEK+W QE ++R+QEEK++
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 659 EHQEHL 664
E +E +
Sbjct: 528 EQEEKM 533
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 1226 bits (3172), Expect = 0.0
Identities = 624/669 (93%), Positives = 633/669 (94%), Gaps = 31/669 (4%)
Query: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
MLMWPQPHLP THPHLPTHPHLPTHPMMSKETRQSKL
Sbjct: 86 MLMWPQPHLP------------------------THPHLPTHPHLPTHPMMSKETRQSKL 121
Query: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA
Sbjct: 122 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 181
Query: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA
Sbjct: 182 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 241
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI
Sbjct: 242 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 301
Query: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE
Sbjct: 302 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 361
Query: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE
Sbjct: 362 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 421
Query: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 420
KEEKMRR EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR
Sbjct: 422 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 481
Query: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 480
QEEKIREQEEKIREQE+KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541
Query: 481 KEKMHEQ-EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI 539
KEK+HEQ EKIRKQEEK+WRQEEKMHDQEEKIREQEEK+WRQEEKIREQEEKIREQEEKI
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI 601
Query: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
REQEEM QEQEEKMGEQEEKM E QEEK++EQEEK+R Q+EKIREQE+KI EQEE
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCE------QEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Query: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE
Sbjct: 656 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
Query: 660 HQEHLEAAI 668
HQEHLEAAI
Sbjct: 716 HQEHLEAAI 724
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 968 bits (2502), Expect = 0.0
Identities = 509/602 (84%), Positives = 540/602 (89%), Gaps = 39/602 (6%)
Query: 1 MLMWPQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
MLMWPQPHLPTH PHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL
Sbjct: 1 MLMWPQPHLPTH------------PHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 48
Query: 61 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 120
AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA
Sbjct: 49 AEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEA 108
Query: 121 LRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 180
LRRELEAQV TIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA
Sbjct: 109 LRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 168
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI
Sbjct: 169 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 228
Query: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288
Query: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
KMWRQ EEKIQE+EEKI+EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE
Sbjct: 289 KMWRQ-------EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 420
KE EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR
Sbjct: 342 KE--------------EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWR 387
Query: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEK---IREEEKRQEQEEMWRQEEKIREQE-E 476
QEEKIREQEEKIREQE+ M QEEK+ EQE+ +EEE ++++E+M RQEEKIREQE +
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
Query: 477 IWRQKEKMHEQEK-IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
I Q+EK+ EQE+ +++QEEK+ QE KM +QE K++EQEEKM RQEEKIREQE+KIREQ
Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507
Query: 536 EEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIREQEEKIREQKEKIREQEEKI 594
EEKIREQEEMMQEQEEKM EQEEKM EQ EKM+ QEEK+R QEEK+REQ+ ++R+QEEK+
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKM 567
Query: 595 WE 596
E
Sbjct: 568 QE 569
Score = 240 bits (612), Expect = 4e-63
Identities = 154/370 (41%), Positives = 236/370 (63%), Gaps = 40/370 (10%)
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRL---EEMMWEKEEKIRELEEKMHE 388
EQ+ + QE + E E +++ + +K E L + + + E + R+L ++H+
Sbjct: 98 EQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 157
Query: 389 QEKIREQEE---------KRQEEEKIREQEKRQEQ-EAKMWRQ---EEKIREQEEKIREQ 435
K + E K++ + I E K ++ +++R +E+++E+ K+ Q
Sbjct: 158 SWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL--Q 215
Query: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR-EQEEIWRQKEKMHEQEKIRKQE 494
EK + EK Q ++E +++ E+ ++ +++++ E + + ++ + + + + + +E
Sbjct: 216 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 275
Query: 495 EKVW-----RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ 549
++W +QEEKM QEEKI+E+EEK+ QEEKIREQEEK+R QEE + E+EE M+ Q
Sbjct: 276 NELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335
Query: 550 EEKMGEQEEKMQE-QEKMRRQEEKIREQEEKIREQKEKIRE-------------QEEKIW 595
EE M E+EEK++E +EKM Q EKIREQEEK R+++EKIRE QEEKI
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQ-EKIREQEEK-RQEEEKIREQEKRQEQEAKMWRQEEKIR 393
Query: 596 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 655
EQEEKIREQEEMMQEQEEKM EQEEKM EQEE+MQEQEEKMRRQEEK+ EQE ++R+QEE
Sbjct: 394 EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEE 453
Query: 656 KMQEHQEHLE 665
K++E +E ++
Sbjct: 454 KIREQEEMMQ 463
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 789 bits (2037), Expect = 0.0
Identities = 417/670 (62%), Positives = 531/670 (79%), Gaps = 51/670 (7%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
PHLP HPMMS++TRQ+KLAEAK++ TD+ VGT A+DTKKKKINNGTNPETTTS
Sbjct: 5 PHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTRATDTKKKKINNGTNPETTTSE 64
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE----G 158
GCHSPEDE+KASHQHQEALRRE+EAQ HTIRILTCQKTEL+ ALYYSQ A ++ E G
Sbjct: 65 GCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLG 124
Query: 159 EARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEE 218
E++DL RLH SW FAGEL++ALSAV+T KKADRYIEELTKERDALSLELYRNTIT+EE
Sbjct: 125 ESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEE 184
Query: 219 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ---LQAEADHLGKELQ 275
LK+KNA+LQEKL+L ESEKSEIQLNVKELKRKLERAK LLPQ Q LQ E +EL+
Sbjct: 185 LKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
Query: 276 SVSAKLQAQVEENELWN---RLNQQ------QEEKMWRQEEKIQEWEEKIQEQEEKIREQ 326
K++ Q E ++W RL +Q QEEKM RQE++++E E++++EQE+++REQ
Sbjct: 245 EQEKKIRKQ--EEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
Query: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW--------------EKEEKMRRLEEMM 372
+ K+REQEE+M+ QEE MWE+EEKMR QEE MW E+E+KMR EE M
Sbjct: 303 K-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
Query: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEK 431
WE++E++RE EE+M EQEK+ EQEEK QEEE+IRE+EK+ +E+E M QEEK+++QEE
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEE-MWRQEEKIREQEEIWRQKEKMHEQEKI 490
+ EQE+K W+Q+ ++EK+ E+EK QEQEE +W QEEKIR+QEE+W Q++KM QEK+
Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481
Query: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ------EEKIREQEE 544
R+QE+++W QEEKM DQE+K+ +QEE+MW Q+E++RE+EE++REQ EEK+RE E+
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE-EK 540
Query: 545 MMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQ 604
QEQE+K +QEEKM+E+E+MR +E+K+RE+EE +REQ+EK++EQEEK+ EQEEK+ EQ
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ 600
Query: 605 EEMMQEQEEKMWEQEEKMCEQEEK---------MQEQEEKMRRQEEKMWEQEVRLRQQEE 655
EE MQEQEEKMWEQEEKM EQEE+ M EQEEKM+ QEEKMWEQE ++R+QEE
Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 660
Query: 656 KMQEHQEHLE 665
KM+E +E ++
Sbjct: 661 KMREQEEKMQ 670
Score = 375 bits (964), Expect = e-104
Identities = 241/589 (40%), Positives = 374/589 (63%), Gaps = 93/589 (15%)
Query: 117 HQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH------DS 170
++E ++ E Q +R+ +K+E+Q+ + + ++LE A+ L+ ++ +
Sbjct: 182 NEELKKKNAELQ-EKLRLAESEKSEIQLNV---KELKRKLE-RAKFLLPQVQTNTLQEEM 236
Query: 171 WKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKL 230
W+ EL + + Q++K R E L ++ + + + ++ L+E+ +L+E+
Sbjct: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQE 296
Query: 231 QLVESEKS----EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 286
+ + +K E Q+ +E K + K+ ++++ + + L ++ + + + Q +
Sbjct: 297 KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
Query: 287 ENE-LWN---RLNQQQE-----EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
+ E +W RL +++E EKMW QEEK+QE EE+I+E+E+K+RE+EE +REQEEKM
Sbjct: 357 QEERMWEQDERLREKEERMREQEKMWEQEEKMQE-EERIREREKKMREEEETMREQEEKM 415
Query: 338 RRQEEMMWEKEEK-------------------MRRQEEMMWEKEEKMRRLEEM------M 372
++QEE MWE+EEK M+ QEE +WE+EEK+R EEM M
Sbjct: 416 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475
Query: 373 WEKEEKIRELEEKMHEQE-KIREQEEKR--------QEEEKIREQEKRQEQEAKMWRQEE 423
W ++EK+RE E++M EQE K+R+QE+K +++E++RE+E+R ++ KMW+QEE
Sbjct: 476 W-RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE 534
Query: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK---------RQEQEEMWRQEEKIREQ 474
K+RE E+K +EQEKK W QEEK+ E+E++RE EK R+++E+M QEEK+REQ
Sbjct: 535 KMRE-EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593
Query: 475 EE-IWRQKEKMHEQE-KIRKQEEKVWRQEEK---------MHDQEEKIREQEEKMWRQEE 523
EE +W Q+EKM EQE K+ +QEEK+W QEE+ M +QEEK++EQEEKMW QEE
Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Query: 524 KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQ-EQEKMRRQEEKIREQEEKIRE 582
K+REQEEK+REQEEK MQ QEEKM EQEEKMQ ++EKMR QEEK+R QEEK+
Sbjct: 654 KMREQEEKMREQEEK-------MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWG 706
Query: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 631
Q+EK+ QEEK+W QEE +RE+EE +++Q+EKM +E++ E EE+ E
Sbjct: 707 QEEKMWGQEEKMWGQEE-MREKEERIRDQKEKM---QERLPEHEERCSE 751
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 746 bits (1925), Expect = 0.0
Identities = 426/769 (55%), Positives = 533/769 (69%), Gaps = 155/769 (20%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
PHLP HPMMS++TRQ+KLAEAK++ TD+ VGT A+DTKKKKIN+GTNPETTTSG
Sbjct: 5 PHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTGATDTKKKKINHGTNPETTTSG 64
Query: 103 GCHSPED----------EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHA 152
GCHSPED E+KASHQHQEALRRE+EAQ HTIRILTCQKTEL+ ALYYSQ A
Sbjct: 65 GCHSPEDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDA 124
Query: 153 VKQLE--------------------------------GEARDLISRLHDSWKFAGELEQA 180
++ E GE++DL RLH SW FAGEL++A
Sbjct: 125 ARKFEDGNLGTPSSFNLALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRA 184
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAV+T+ KKADRYIEELTKERDALSLELYRNTIT+EELK+KNA+LQEKL L ESEKSEI
Sbjct: 185 LSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEI 244
Query: 241 QLNVKELKRKLERAKLLLPQQQ---LQAEADHLGKELQSVSAKLQAQVEENELW---NRL 294
QLNVKELKRKLERAK LLPQ Q LQ E +EL+ K++ Q E ++W RL
Sbjct: 245 QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ--EEKMWRQEERL 302
Query: 295 NQQ------QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
+Q QEEKMWRQE++++E E++++EQE+++REQ+E +REQEE+M+ QEE MWE+E
Sbjct: 303 REQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE-LREQEEQMQEQEEKMWEQE 361
Query: 349 EKMRRQEEMMW--------------EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE 394
EKMR QEE MW E+E+KMR EE MWE++E++RE EE+M EQEK+ E
Sbjct: 362 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 421
Query: 395 QEEKRQEEEKIREQEKR--------------QEQEAKMWRQEEKIREQEEKIREQEKKMW 440
Q EK +EE+K++EQEK+ +E+E KM +EE +REQEEK+++QE+ MW
Sbjct: 422 QVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 481
Query: 441 RQEEKIHEQ-------EKIREEEKRQEQEE-MWRQEEKIREQEEIWRQKEKMHEQEKIRK 492
QEEK +Q EK+ E+EK QEQEE +W QEEKIR+QEE+W Q++KM QEK+R+
Sbjct: 482 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541
Query: 493 QEEKVWRQEEKMHDQEEKI-----------REQEEKMWRQEEKIREQEEKIREQEEKIRE 541
QE+++W QEEKM DQE+K+ +EQE+K W QEEK+RE EE++RE+E+K+RE
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE-EERMREREKKMRE 600
Query: 542 QEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE-- 598
+EEMM+EQEEKM EQEEKMQEQ EKM QEEK++EQEEK+ EQ+EK+ EQEEK+WEQ+
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 599 ----------EKIREQEEMMQEQEEKMWEQ------------------------------ 618
EK++EQE+ MQEQEEK+WEQ
Sbjct: 661 PEQKEKLWEHEKMQEQEK-MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719
Query: 619 ------EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
EE M EQEEKMQEQEEKM+ QEE+MWEQE ++ +QEEKM E Q
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768
Score = 419 bits (1077), Expect = e-117
Identities = 264/591 (44%), Positives = 378/591 (63%), Gaps = 46/591 (7%)
Query: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 169
EQ+ QE RE E ++ ++ EL+ Q +++ + + +
Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
Query: 170 SWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK 229
W+ L + + Q++K R EE E+D E E++ E+ K++E+
Sbjct: 371 MWRQEERLWEQEKQMREQEQKM-RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE 429
Query: 230 LQLVESEKS--EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
++ E EK + + ++E +R ER K + +++ E + +++Q + Q EE
Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQE---EKMQKQEENMWEQ-EE 485
Query: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE-----KIREQEEKMRRQEE 342
E + +Q+EK+W QE K+QE EEKI EQEEKIR+QEE K ++EKMR QE+
Sbjct: 486 KEWQQQRLPEQKEKLWEQE-KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 544
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRR----LEEMMWEKEEKIRELEEKMHEQE-KIREQEE 397
MWE+EEKMR QE+ MW++EE+M + E+ W++EEK+RE EE+M E+E K+RE+EE
Sbjct: 545 QMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEE 603
Query: 398 -KRQEEEKIREQ-EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ------ 449
R++EEK++EQ EK QEQE KMW QEEK++EQEEK+ EQE+KMW QEEK+ EQ
Sbjct: 604 MMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663
Query: 450 -EKIREEEKRQEQEEMWRQEEKIREQEEIWRQ----------KEKMHEQEKIRKQEEKVW 498
EK+ E EK QEQE+M QEEKI EQE++ ++ +EKM E+E +R++E+K+
Sbjct: 664 KEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Query: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQE-----EKM 553
+EE M +QEEK++EQEEKM QEE++ EQEEK+ EQEEK+ EQ+ + +++E EKM
Sbjct: 724 EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 783
Query: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE 613
EQE+ +++EKMR QEEK+R QEEK+R Q+EK+R QEEK+W QEEK+ QEE M QEE
Sbjct: 784 QEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 843
Query: 614 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
KMW QEEKM EEKMQ QEEKMR QEEKM QE ++R+QEEKM+ +E +
Sbjct: 844 KMWGQEEKM---EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 357 bits (916), Expect = 2e-98
Identities = 222/528 (42%), Positives = 335/528 (63%), Gaps = 41/528 (7%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E EQK Q + ++ + R+ +K Q+ + +++ E + RD ++
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM 446
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL- 226
+ + E E+ + ++++ R EE ++++ E + L E+ KL
Sbjct: 447 QEEERIR-EREKKMR----EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 501
Query: 227 -QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
QEK+Q E + E + +++ + + K + Q++++ + D + ++ + + + Q
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 561
Query: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
++ E + Q+QE+K W QEEK++E EE++RE+E+K+RE+EE MR QEE M
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMRE--------EERMREREKKMREEEEMMREQEEKMQ 613
Query: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 405
E+EEKM+ QEE MWE+EEKM+ EE MWE+EEK+ E EEKM EQ+++ EQ+EK E EK+
Sbjct: 614 EQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673
Query: 406 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW-----RQEEKIHEQEK-IREEEK-- 457
+EQEK QEQE K+W QE+ E+K +EQEKK W R+EE + E+EK +REEE+
Sbjct: 674 QEQEKMQEQEEKIWEQEK----MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMM 729
Query: 458 RQEQEEMWRQEEKIREQEE--------IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE 509
R+++E+M QEEK++EQEE +W Q+EKM EQ+++ +Q+EK+W + EKM +Q E
Sbjct: 730 REQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLW-EHEKMQEQ-E 787
Query: 510 KIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM-QEQEKMRR 568
KI EQEEKM QEEK+R QEEK+R QEEK+R QEE M QEEKM QEEKM ++EKM
Sbjct: 788 KIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWG 847
Query: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616
QEEK+ EEK++ Q+EK+REQEEK+ QEEK+REQEE M+ QEEK++
Sbjct: 848 QEEKM---EEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIY 892
Score = 288 bits (736), Expect = 1e-77
Identities = 181/476 (38%), Positives = 289/476 (60%), Gaps = 43/476 (9%)
Query: 196 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNV---KELKRKLE 252
E+ + R L E + E L+ + ++++ +K+E++ + ++ RK E
Sbjct: 70 EDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFE 129
Query: 253 RAKLLLPQQ-QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
L P L G L VS L E +L RL+ W ++Q
Sbjct: 130 DGNLGTPSSFNLALSQAFRGSPLGCVSTSL-IPGESKDLAGRLHHS-----WHFAGELQR 183
Query: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM 371
+ + +K E++ ++ + + + E+++++ E +EK+ E
Sbjct: 184 ALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNA---ELQEKLPLAESE 240
Query: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 431
E + ++EL+ K+ + + Q + +E+ MWRQEE++REQE+K
Sbjct: 241 KSEIQLNVKELKRKLERAKFLLPQVQTNTLQEE-------------MWRQEEELREQEKK 287
Query: 432 IREQEKKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK-MHEQEK 489
IR+QE+KMWRQEE++ EQE K+RE+E E+MWRQE+++REQE+ R++EK + EQ++
Sbjct: 288 IRKQEEKMWRQEERLREQEGKMREQE-----EKMWRQEKRLREQEKELREQEKELREQKE 342
Query: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ 549
+R+QEE++ QEEKM +QEEK+REQEEKMWRQEE++ EQE+++REQE+K+R+QEE M EQ
Sbjct: 343 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 402
Query: 550 EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ 609
+E++ E+EE+M+EQEKM Q EK+RE++ K++EQE+K +QEEK++E EE ++
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEK--------KMQEQEKKTRDQEEKMQE-EERIR 453
Query: 610 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
E+E+KM E+EE M EQEEKMQ+QEE M QEEK W+Q+ RL +Q+EK+ E ++ E
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ-RLPEQKEKLWEQEKMQE 508
Score = 188 bits (478), Expect = 1e-47
Identities = 142/415 (34%), Positives = 223/415 (53%), Gaps = 67/415 (16%)
Query: 107 PEDEQKA----SHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
PE ++K Q QE E E ++ + Q+ ++ + Q +++ E + +
Sbjct: 494 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM-----WRQEKMREQEDQMWE 548
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
++ D + + E+ + +++K EE +E + + + +E ++E+
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608
Query: 223 NAKLQE---KLQLVESEKSEIQLNVKELKRKL--------ERAKLLLPQQQLQAEADHLG 271
K+QE K+Q E + E + ++E + K+ E+ + + QQ+L + + L
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 272 K-ELQSVSAKLQAQVE---ENELWNRLNQQQEEKMW-----RQEEKIQEWEEKIQEQEEK 322
+ E K+Q Q E E E + Q+QE+K W R+EE ++E E+K++E+EE
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728
Query: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE------------EKMRRLEE 370
+REQEEK++EQEEKM+ QEE MWE+EEKM QEE MWE++ EKM+ +E
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQE-QE 787
Query: 371 MMWEKEEKIRELEEKMH--------EQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWR 420
+WE+EEK+R+ EEKM ++EK+R QEEK QEE+ ++EK QE KMW
Sbjct: 788 KIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWG 847
Query: 421 QEEKIRE----QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471
QEEK+ E QEEK+REQE+KM QEEK+ EQE E+M QEEKI
Sbjct: 848 QEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQE-----------EKMRGQEEKI 891
Score = 150 bits (380), Expect = 3e-36
Identities = 127/405 (31%), Positives = 203/405 (50%), Gaps = 70/405 (17%)
Query: 53 KETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQK 112
K RQ K+ E ++Q+ + + D ++K + E T D+++
Sbjct: 532 KMWRQEKMREQEDQMWEQEEKMR--------DQEQKMWDQEERMEKKTQEQEKKTWDQEE 583
Query: 113 ASHQHQEALRRE--LEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDS 170
+ + RE + + +R + E + + + + + E + ++ ++ +
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 171 WKFAGELEQAL---SAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
+ E E+ + + QK+K + E K ++ ++ I ++E EK + Q
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEK----LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ 699
Query: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
EK + + EK + +++E ++K+ + ++ +Q+ +++Q K+Q Q E
Sbjct: 700 EK-KTWDQEKMREEESMREREKKMREEEEMMREQE---------EKMQEQEEKMQEQ--E 747
Query: 288 NELWNRLNQQQEEKMWRQEEKIQE-----------WE-------EKIQEQEEKIREQEEK 329
E+W +QEEKMW QEEK+ E WE EKI EQEEK+R+QEEK
Sbjct: 748 EEMW-----EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802
Query: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH-E 388
+R QEEKMR QEE M +EEKM QEE MW +EEKM EE MW +EEK +EEKM +
Sbjct: 803 MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK---MEEKMQGQ 859
Query: 389 QEKIREQEEK-RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 432
+EK+REQEEK R +EEK+RE QEEK+R QEEKI
Sbjct: 860 EEKMREQEEKMRGQEEKMRE-------------QEEKMRGQEEKI 891
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 500 bits (1288), Expect = e-141
Identities = 279/466 (59%), Positives = 353/466 (75%), Gaps = 28/466 (6%)
Query: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
YIE+LTKERDALSLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 191 YIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE E
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
Query: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
EK+ EQE KIREQEEK+ QEEKM QEE + E+E+KM RQEE + E+EEK+R EE MW
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
Query: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
+EEKIRE +EK+ EQE EE ++EEKIREQE+++++ KMWRQE+K+REQ+EKIR
Sbjct: 371 RQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEEKRQE--KMWRQEKKMREQDEKIR 423
Query: 434 EQEKKMWRQEEKIHEQEKI---REEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI 490
EQE++MWRQEEKI E E++ +EE+ R+ +E+M +EEK++EQEE + ++EKI
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE-----KIQRQEEKI 478
Query: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQE 550
++QEEK WRQ EK+ QEEKI EQEEKMWRQEEK+ EQEEK++EQEEK++ QEE M+EQE
Sbjct: 479 QEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537
Query: 551 EKMGEQEEKMQEQE-KMRRQEEKIREQEEKI-------REQKEKIREQEEKIWEQEEKIR 602
++ +QEEKMQEQE +++ EE++ + +K RE + I + E K +
Sbjct: 538 VRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQ 597
Query: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE----KMRRQEEKMW 644
E + + Q+Q+ ++ + ++ +E R+ K W
Sbjct: 598 EAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643
Score = 355 bits (911), Expect = 7e-98
Identities = 221/517 (42%), Positives = 310/517 (59%), Gaps = 57/517 (11%)
Query: 162 DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 221
D + DS + L++ + + D + + K D + + E++ E
Sbjct: 88 DDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKR---QEKMNE 144
Query: 222 KNAKLQEKLQLVES--EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
KN ++++ + + E+ + LE ++ + L KE ++S
Sbjct: 145 KNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSL 204
Query: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR- 338
+L +E N + +EK+ E + E + +++ + K+ + + +Q+ ++
Sbjct: 205 ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEA 264
Query: 339 -RQEEMMWEKEEKMRRQ--EEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
R + + K++ Q E +W + + EE MW +EEKI+E EEKM EQE
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQ--EEKMWRQEEKIQEQEEKMCEQEL---- 318
Query: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 455
KIREQE+ KMWRQEEK+ EQEEKIREQE KMWRQEEKI EQE E
Sbjct: 319 --------KIREQEE------KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE----E 360
Query: 456 EKRQEQEEMWRQEEKIREQ--------EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
+ R+++E+MWRQEEKIREQ EE+WRQ+EK+ EQE+ K++EK+WRQE+KM +Q
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE--KRQEKMWRQEKKMREQ 418
Query: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
+EKIREQEE+MWRQEEKIRE EE +++QEEK+RE EE MQE+EEKM EQEEK+Q
Sbjct: 419 DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ------ 472
Query: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
RQEEKI+EQEEK Q EK+ +QEEKIWEQEEK M QEEKMWEQEEKM EQEE
Sbjct: 473 RQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEK-------MWRQEEKMWEQEEKMQEQEE 524
Query: 628 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
KMQ QEEKMR QE ++W+QE ++++QE ++QE +E L
Sbjct: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 351 bits (900), Expect = 1e-96
Identities = 217/504 (43%), Positives = 316/504 (62%), Gaps = 66/504 (13%)
Query: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 271
+++ E +N K + + E + E + K+ K L+R LP + +A H+
Sbjct: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
Query: 272 K---ELQSVSAKLQAQVEENEL-----------WNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
K E++S K Q ++ E W RL + +K R E + E E
Sbjct: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQK--RPENSLLE-ETLHF 182
Query: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEE 377
+ ++ EK+ ++ + + + +E+++ + E +EK+R +E E +
Sbjct: 183 DHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239
Query: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-------------------RQEQEAKM 418
+++L+ K+ + + Q++ + E +++ ++ + Q+QE KM
Sbjct: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKM 299
Query: 419 WRQEEKIREQEEK-------IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471
WRQEEKI+EQEEK IREQE+KMWRQEEK+HEQE E+ R+++++MWRQEEKI
Sbjct: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE----EKIREQEDKMWRQEEKI 355
Query: 472 REQEE--------IWRQKEKMHEQ-EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE 522
REQEE +WRQ+EK+ EQ EKI++QEE++WRQEEK+ +QEEK ++EKMWRQE
Sbjct: 356 REQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK---RQEKMWRQE 412
Query: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE-QEKMRRQEEKIREQEEKIR 581
+K+REQ+EKIREQEE++ QEE ++E EE M +QEEK++E +EKM+ +EEK++EQEEKI+
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 582 EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
Q+EKI+EQEEK W Q EK+ +QEE + EQEEKMW QEEKM EQEEKMQEQEEKM+RQEE
Sbjct: 473 RQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
Query: 642 KMWEQEVRLRQQEEKMQEHQEHLE 665
KM EQEVRL QQEEKMQE + L+
Sbjct: 532 KMREQEVRLWQQEEKMQEQEVRLQ 555
Score = 256 bits (654), Expect = 5e-68
Identities = 166/477 (34%), Positives = 276/477 (57%), Gaps = 58/477 (12%)
Query: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 288
K ++ E S++ ++ +L+ QQ H +S++ + Q+ E
Sbjct: 21 KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69
Query: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-----EQEEKIR------------ 331
E + +++ K W +++ ++E E+ Q +E R +E I
Sbjct: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
E + ++++E M EK R++ + ++ RL E+ +K + LEE +H
Sbjct: 130 EVKSSFKKRQEKMNEKNYTFRKRVVI----KKPWLRLGEVTAQKRPENSLLEETLHFDHA 185
Query: 392 IR-----EQEEKRQE------------EEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
+R E+ K ++ +E+++E K E + K+ E + E + +++
Sbjct: 186 VRMGTYIEKLTKERDALSLELYRNTITDEELKE--KNAELQEKLRLVESEKSEIQLNVKD 243
Query: 435 QEKKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
++K+ R + + +Q+ ++ + +E + + + + E+ E+W + E EK+ +Q
Sbjct: 244 LKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQE-EKMWRQ 302
Query: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
EEK+ QEEKM +QE KIREQEEKMWRQEEK+ EQEEKIREQE+K+ QEE ++EQEEK+
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKI 362
Query: 554 GEQEEKM-QEQEKMRRQEEKIREQEEKIREQKEKIREQE----EKIWEQEEKIREQEEMM 608
EQEEKM +++EK+R Q+EKI+EQEE++ Q+EKIREQE EK+W QE+K+REQ+E +
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKI 422
Query: 609 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
+EQEE+MW QEEK+ E EE MQ+QEEK+R EEKM E+E ++++QEEK+Q +E ++
Sbjct: 423 REQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 498 bits (1281), Expect = e-141
Identities = 278/466 (59%), Positives = 352/466 (75%), Gaps = 28/466 (6%)
Query: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
YIE+LTKERDA SLELYRNTITDEELKEKNA+LQEKL+LVESEKSEIQLNVK+LKRKLER
Sbjct: 191 YIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
A+LLLPQQQLQ EAD LGKELQSVSAKLQAQVEENELWN LNQQQEEKMWRQEEKIQE E
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
Query: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
EK+ EQE KIREQEEK+ QEEKM QEE + E+E+KM RQEE + E+EEK+R EE MW
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
Query: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
+EEKIRE +EK+ EQE EE ++EEKIREQE+++++ KMWRQE+K+REQ+EKIR
Sbjct: 371 RQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEEKRQE--KMWRQEKKMREQDEKIR 423
Query: 434 EQEKKMWRQEEKIHEQEKI---REEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI 490
EQE++MWRQEEKI E E++ +EE+ R+ +E+M +EEK++EQEE + ++EKI
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEE-----KIQRQEEKI 478
Query: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQE 550
++QEEK WRQ EK+ QEEKI EQEEKMWRQEEK+ EQEEK++EQEEK++ QEE M+EQE
Sbjct: 479 QEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE 537
Query: 551 EKMGEQEEKMQEQE-KMRRQEEKIREQEEKI-------REQKEKIREQEEKIWEQEEKIR 602
++ +QEEKMQEQE +++ EE++ + +K RE + I + E K +
Sbjct: 538 VRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQ 597
Query: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE----KMRRQEEKMW 644
E + + Q+Q+ ++ + ++ +E R+ K W
Sbjct: 598 EAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPSCSSRKLRAKRW 643
Score = 354 bits (908), Expect = 2e-97
Identities = 221/517 (42%), Positives = 309/517 (59%), Gaps = 57/517 (11%)
Query: 162 DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 221
D + DS + L++ + + D + + K D + + E++ E
Sbjct: 88 DDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKR---QEKMNE 144
Query: 222 KNAKLQEKLQLVES--EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
KN ++++ + + E+ + LE ++ + L KE + S
Sbjct: 145 KNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSL 204
Query: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR- 338
+L +E N + +EK+ E + E + +++ + K+ + + +Q+ ++
Sbjct: 205 ELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEA 264
Query: 339 -RQEEMMWEKEEKMRRQ--EEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
R + + K++ Q E +W + + EE MW +EEKI+E EEKM EQE
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQ--EEKMWRQEEKIQEQEEKMCEQEL---- 318
Query: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 455
KIREQE+ KMWRQEEK+ EQEEKIREQE KMWRQEEKI EQE E
Sbjct: 319 --------KIREQEE------KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE----E 360
Query: 456 EKRQEQEEMWRQEEKIREQ--------EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
+ R+++E+MWRQEEKIREQ EE+WRQ+EK+ EQE+ K++EK+WRQE+KM +Q
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE--KRQEKMWRQEKKMREQ 418
Query: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
+EKIREQEE+MWRQEEKIRE EE +++QEEK+RE EE MQE+EEKM EQEEK+Q
Sbjct: 419 DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ------ 472
Query: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
RQEEKI+EQEEK Q EK+ +QEEKIWEQEEK M QEEKMWEQEEKM EQEE
Sbjct: 473 RQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEK-------MWRQEEKMWEQEEKMQEQEE 524
Query: 628 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
KMQ QEEKMR QE ++W+QE ++++QE ++QE +E L
Sbjct: 525 KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 349 bits (896), Expect = 4e-96
Identities = 217/504 (43%), Positives = 315/504 (62%), Gaps = 66/504 (13%)
Query: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA--DHLG 271
+++ E +N K + + E + E + K+ K L+R LP + +A H+
Sbjct: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
Query: 272 K---ELQSVSAKLQAQVEENEL-----------WNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
K E++S K Q ++ E W RL + +K R E + E E
Sbjct: 126 KNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQK--RPENSLLE-ETLHF 182
Query: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEE 377
+ ++ EK+ ++ + + +E+++ + E +EK+R +E E +
Sbjct: 183 DHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNA---ELQEKLRLVESEKSEIQL 239
Query: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-------------------RQEQEAKM 418
+++L+ K+ + + Q++ + E +++ ++ + Q+QE KM
Sbjct: 240 NVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKM 299
Query: 419 WRQEEKIREQEEK-------IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471
WRQEEKI+EQEEK IREQE+KMWRQEEK+HEQE E+ R+++++MWRQEEKI
Sbjct: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE----EKIREQEDKMWRQEEKI 355
Query: 472 REQEE--------IWRQKEKMHEQ-EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE 522
REQEE +WRQ+EK+ EQ EKI++QEE++WRQEEK+ +QEEK ++EKMWRQE
Sbjct: 356 REQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK---RQEKMWRQE 412
Query: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE-QEKMRRQEEKIREQEEKIR 581
+K+REQ+EKIREQEE++ QEE ++E EE M +QEEK++E +EKM+ +EEK++EQEEKI+
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 582 EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
Q+EKI+EQEEK W Q EK+ +QEE + EQEEKMW QEEKM EQEEKMQEQEEKM+RQEE
Sbjct: 473 RQEEKIQEQEEKTWRQ-EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
Query: 642 KMWEQEVRLRQQEEKMQEHQEHLE 665
KM EQEVRL QQEEKMQE + L+
Sbjct: 532 KMREQEVRLWQQEEKMQEQEVRLQ 555
Score = 256 bits (655), Expect = 4e-68
Identities = 165/475 (34%), Positives = 273/475 (57%), Gaps = 54/475 (11%)
Query: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 288
K ++ E S++ ++ +L+ QQ H +S++ + Q+ E
Sbjct: 21 KSPVLSDEDSDLDFHINKLE-----------QQSKVRNKGHGKPREKSIADEKFFQLSEM 69
Query: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR-----EQEEKIR------------ 331
E + +++ K W +++ ++E E+ Q +E R +E I
Sbjct: 70 EAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSD 129
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
E + ++++E M EK R++ + ++ RL E+ +K + LEE +H
Sbjct: 130 EVKSSFKKRQEKMNEKNYTFRKRVVI----KKPWLRLGEVTAQKRPENSLLEETLHFDHA 185
Query: 392 IR-----EQEEKRQEEEKIRE----------QEKRQEQEAKMWRQEEKIREQEEKIREQE 436
+R E+ K ++ + +EK E + K+ E + E + +++ +
Sbjct: 186 VRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLK 245
Query: 437 KKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEE 495
+K+ R + + +Q+ ++ + +E + + + + E+ E+W + E EK+ +QEE
Sbjct: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQE-EKMWRQEE 304
Query: 496 KVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555
K+ QEEKM +QE KIREQEEKMWRQEEK+ EQEEKIREQE+K+ QEE ++EQEEK+ E
Sbjct: 305 KIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIRE 364
Query: 556 QEEKM-QEQEKMRRQEEKIREQEEKIREQKEKIREQE----EKIWEQEEKIREQEEMMQE 610
QEEKM +++EK+R Q+EKI+EQEE++ Q+EKIREQE EK+W QE+K+REQ+E ++E
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 611 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
QEE+MW QEEK+ E EE MQ+QEEK+R EEKM E+E ++++QEEK+Q +E ++
Sbjct: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 379 bits (973), Expect = e-105
Identities = 222/456 (48%), Positives = 343/456 (75%), Gaps = 30/456 (6%)
Query: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
IT+EELKEKNA+LQE+LQLVE+EKSEIQL++KELKRKLE K+ LPQ+ E +
Sbjct: 4 ITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQE----- 58
Query: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
QV E E R +QE ++ QE +++E E +++EQE ++REQE ++REQ
Sbjct: 59 ---------GQVREQEGQVR---EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 106
Query: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE-KI 392
E ++R QE + E+E ++R QE + E+E ++R E + E+E ++RE E ++ EQE ++
Sbjct: 107 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 166
Query: 393 REQE-EKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 450
REQE + R++E ++REQE + +EQE +M QE ++ EQEE++ EQE++M +QEE++ EQE
Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQE 226
Query: 451 KIREEEKRQEQEE-MWRQEEKIREQEE-IWRQKEKMHEQ-EKIRKQEEKVWRQEEKMHDQ 507
E+ ++QEE M QEE++++QEE + +Q+E+M +Q E++R+QEE++ QEE+M Q
Sbjct: 227 -----EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQ 281
Query: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKM 566
+E+ EQEE+ QEE++REQEE++REQEE++REQEE M+EQEE+MG+QEE+M EQ E+M
Sbjct: 282 KEQ-TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
Query: 567 RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 626
Q+E++ +QEE++ EQ+E++++QEE++ +QEE++R+QEE M++QEE+M +QEE+M EQ+
Sbjct: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK 400
Query: 627 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
E+M EQ+E+MR QEE+M EQ+ ++R+QEE M E +E
Sbjct: 401 EQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 307 bits (786), Expect = 2e-83
Identities = 172/397 (43%), Positives = 289/397 (72%), Gaps = 25/397 (6%)
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQEEKIREQEEKI 330
+EL+ +A+LQ +++ E ++ E ++ +E K + +KI QE ++REQE ++
Sbjct: 7 EELKEKNAELQEELQLVE-----TEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQV 61
Query: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE 390
REQE ++R QE + E+E ++R QE + E+E ++R E + E+E ++RE E ++ EQE
Sbjct: 62 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121
Query: 391 -KIREQE-EKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
++REQE + R++E ++REQE + +EQE ++ QE ++REQE ++REQE ++ QE ++
Sbjct: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 181
Query: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
EQE + R+++ +M QE ++ EQEE ++ +QEE++ +QEE+M +Q
Sbjct: 182 EQEG----QVREQEGQMGEQEGQMGEQEE------------QMGEQEEQMQKQEEQMGEQ 225
Query: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
EE++R+QEE+M QEE++++QEE++++QEE++R+QEE M+EQEE+M EQEE+M +Q++
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
Query: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
QEE+ EQEE++REQ+E++REQEE++ EQEE++REQEE M +QEE+MWEQ+E+M EQ+E
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE 345
Query: 628 KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
+M +QEE+M QEE+M +QE ++R+QEE+M++ +E +
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQM 382
Score = 297 bits (760), Expect = 2e-80
Identities = 173/445 (38%), Positives = 311/445 (69%), Gaps = 30/445 (6%)
Query: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
EL++ L V T+K + +I+EL ++ + + L + + +++E+ +++E+ V
Sbjct: 15 ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQ----EGQVREQEGQVREQEGQVRE 70
Query: 236 EKSEI---QLNVKELKRKLERAKLLLPQQQLQA-EADHLGKELQSVSAKLQAQVEENELW 291
++ ++ + V+E + ++ + + +Q+ Q E + +E + + + QV E E
Sbjct: 71 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 130
Query: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
R +QE ++ QE +++E E +++EQE ++REQE ++REQE ++R QE + E+E ++
Sbjct: 131 VR---EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187
Query: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ-EKIREQEEK--RQEEEKIREQ 408
R QE M E+E +M EE M E+EE++++ EE+M EQ E++R+QEE+ QEE+ +++
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
Query: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 468
E+ Q+QE +M +QEE++REQEE++REQE++M +Q+E+ ++E+ E+E E+M QE
Sbjct: 248 EQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQE-----EQMREQE 302
Query: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ 528
E++REQEE R++E E++R+QEE++ +QEE+M +Q+E++ EQ+E+MW+QEE++ EQ
Sbjct: 303 EQMREQEEQMREQE-----EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ 357
Query: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIR 588
EE++++QEE++R+QEE M++QEE+M +QE E+MR+QEE++ EQ+E++ EQKE++R
Sbjct: 358 EEQMQKQEEQVRKQEEQMRKQEEQMRKQE------EQMRKQEEQMGEQKEQMGEQKEQMR 411
Query: 589 EQEEKIWEQEEKIREQEEMMQEQEE 613
EQEE++ EQ+E++R+QEE M EQ+E
Sbjct: 412 EQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 146 bits (369), Expect = 5e-35
Identities = 93/328 (28%), Positives = 198/328 (60%), Gaps = 24/328 (7%)
Query: 110 EQKASHQHQEALRRELEAQVHT----IRILTCQKTELQMALYYSQHAVKQLEGEARDLIS 165
EQ+ + QE RE E QV +R Q E + + + V++ EG+ R+
Sbjct: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185
Query: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
++ + GE E + Q+++ E++ K+ + + + +E+++++ +
Sbjct: 186 QVREQEGQMGEQE---GQMGEQEEQMGEQEEQMQKQEEQMGEQ-------EEQMRKQEEQ 235
Query: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
+ E+ + V+ ++ ++Q ++++++ E+ + ++Q++ + + + K+ + + Q
Sbjct: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE--QEEQMREQEEQMLKQKEQTEQEEQTGE 293
Query: 286 EENELWNRLNQ--QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 343
+E ++ + Q +QEE+M QEE+++E EE++ +QEE++ EQ+E++ EQ+E+M +QEE
Sbjct: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353
Query: 344 MWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 403
M E+EE+M++QEE + ++EE+MR+ EE M ++EE++R+ EE+M EQ +E+ +++E
Sbjct: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ-----KEQMGEQKE 408
Query: 404 KIREQEKRQ-EQEAKMWRQEEKIREQEE 430
++REQE++ EQ+ +M +QEE + EQ+E
Sbjct: 409 QMREQEEQMGEQKEQMRKQEEHMGEQKE 436
>gi|239750781 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 307
Score = 323 bits (829), Expect = 2e-88
Identities = 173/260 (66%), Positives = 196/260 (75%), Gaps = 42/260 (16%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
PHLP HPMMS++TRQ+KLAEAK++ TD+ VGT A+DTKKKKIN+GTNPETTTSG
Sbjct: 5 PHLPPHPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTGATDTKKKKINHGTNPETTTSG 64
Query: 103 GCHSPED----------EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHA 152
GCHSPED E+KASHQHQEALRRE+EAQ HTIRILTCQKTEL+ ALYYSQ A
Sbjct: 65 GCHSPEDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDA 124
Query: 153 VKQLE--------------------------------GEARDLISRLHDSWKFAGELEQA 180
++ E GE++DL RLH SW FAGEL++A
Sbjct: 125 ARKFEDGNLGTPSSFNLALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRA 184
Query: 181 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 240
LSAV+T+ KKADRYIEELTKERDALSLELYRNTIT+EELK+KNA+LQEKL+L ESEKSEI
Sbjct: 185 LSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEI 244
Query: 241 QLNVKELKRKLERAKLLLPQ 260
QLNVKELKRKLERAK LLPQ
Sbjct: 245 QLNVKELKRKLERAKFLLPQ 264
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 261 bits (666), Expect = 2e-69
Identities = 180/535 (33%), Positives = 301/535 (56%), Gaps = 87/535 (16%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP HP MS++T+Q KLA AK++L + + +P G A +KKKI NG++P+T TSG
Sbjct: 5 PRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSP--GIPAGANRKKKI-NGSSPDTATSG 61
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
G HSP D + E A T+ L Q EL +AL S + QL
Sbjct: 62 GYHSPGDS-------ATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQL------ 108
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
E S V T K++ I + K L L++ LK +
Sbjct: 109 --------------TENINSLVRTSKEEKKHEIHLVQK----LGRSLFK-------LKNQ 143
Query: 223 NAK-LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
A+ L + S+ ++Q L+++LE +G++L
Sbjct: 144 TAEPLAPEPPAGPSKVEQLQDETNHLRKELE----------------SVGRQL------- 180
Query: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
QA+VE N++ + LN++QEE++ QEE+++E EE+++EQEE++ EQEE++REQEE++R QE
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQE 240
Query: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ-EKIREQEEK-R 399
E + E+EE++R EE + E+EE+ + E+EE++RE EE++HEQ E++ EQEE+ R
Sbjct: 241 ERLCEQEERLREHEERLCEQEER-------LCEQEERLREQEERLHEQEERLCEQEERLR 293
Query: 400 QEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 458
++EE++ EQE+R +EQE ++ QEE++REQEE++ EQE K+ QE + E EK+ E+E+R
Sbjct: 294 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQE-KLPGQERLLEEVEKLLEQERR 352
Query: 459 QEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE-----EKMHDQEEKIRE 513
QE ++E++ E+E + + E++ EQE++R+Q+E++W+QE E++ + E +
Sbjct: 353 QE------EQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLEL 406
Query: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRR 568
E ++ Q + R E++ + + + E+ ++E ++ G +E + E R
Sbjct: 407 GWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAAR 461
Score = 197 bits (500), Expect = 3e-50
Identities = 122/330 (36%), Positives = 206/330 (62%), Gaps = 28/330 (8%)
Query: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE--EKI-REQ 408
R + + E + + L + I +L E ++ + ++E+K + +K+ R
Sbjct: 78 RASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSL 137
Query: 409 EKRQEQEAKMWRQEEKIREQE-EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 467
K + Q A+ E + E+++++ + ++ E + Q + E + RQ
Sbjct: 138 FKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQ 197
Query: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
EE++REQEE R++E E++R+QEE++ QEE++ +QEE++REQEE++ QEE++RE
Sbjct: 198 EERLREQEERLREQE-----ERLREQEERLCEQEERLREQEERLREQEERLCEQEERLRE 252
Query: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
EE++ EQEE++ EQEE ++EQEE++ EQEE++ E QEE++REQEE++ EQ+E++
Sbjct: 253 HEERLCEQEERLCEQEERLREQEERLHEQEERLCE------QEERLREQEERLCEQEERL 306
Query: 588 REQEEKIWEQEEKIREQEEMMQEQE-----EKMWEQEEKMCEQEEKMQEQE-----EKMR 637
REQEE++ EQEE++REQEE + EQE E++ E+ EK+ EQE + +EQE E++
Sbjct: 307 REQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLL 366
Query: 638 RQEEKMWEQEVRLRQQEEKM--QEHQEHLE 665
+ E++ EQE RLRQQ+E++ QE + LE
Sbjct: 367 EEVEELLEQE-RLRQQDERLWQQETLQELE 395
Score = 192 bits (487), Expect = 1e-48
Identities = 107/284 (37%), Positives = 192/284 (67%), Gaps = 26/284 (9%)
Query: 374 EKEEKIRELEEKMHEQEKI-----REQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIRE 427
E E R+L+ ++ + + R++E R++EE++REQE+R +EQE ++ QEE++RE
Sbjct: 172 ELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLRE 231
Query: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487
QEE++REQE+++ QEE++ E EE +++E + QEE++REQE E++HEQ
Sbjct: 232 QEERLREQEERLCEQEERLRE----HEERLCEQEERLCEQEERLREQE------ERLHEQ 281
Query: 488 -EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM 546
E++ +QEE++ QEE++ +QEE++REQEE++ QEE++REQEE++ EQ EK+ QE ++
Sbjct: 282 EERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ-EKLPGQERLL 340
Query: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE-----EKI 601
E+ EK+ EQE + +EQE++ +E + E EE + ++E++R+Q+E++W+QE E++
Sbjct: 341 -EEVEKLLEQERRQEEQERLLERERLLEEVEELL--EQERLRQQDERLWQQETLQELERL 397
Query: 602 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 645
RE E M++ E ++EQ + E++ + + + E+++ E
Sbjct: 398 RELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKE 441
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 238 bits (608), Expect = 1e-62
Identities = 179/668 (26%), Positives = 362/668 (54%), Gaps = 91/668 (13%)
Query: 53 KETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQK 112
+E RQ +L +E+ + + + +++++ E S E E++
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 113 ASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEAR--DLISRLHDS 170
Q+ LRRE + + + +K+ E E R + R H+
Sbjct: 643 ----RQQQLRREQQER--------------------REQRLKREEEEERLEQRLKREHEE 678
Query: 171 WKFAGELEQALSAVATQ--KKKADRYIEELTKERDALSLELYRNTITDE------ELKEK 222
+ EL + A + K + ++ +L E DA ++Y E E +EK
Sbjct: 679 ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEK 738
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKR----------KLERAKLLL---PQQQLQAEADH 269
+ + +LQ E E++ Q +E +R K ER + L P + Q E
Sbjct: 739 RRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQL 798
Query: 270 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW--RQEEKIQEWE--EKIQEQEEKIRE 325
+E Q + + EE E R +++E+++ +EE++Q E +++QE+E+ ++E
Sbjct: 799 RAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE 858
Query: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK---EEKMRRLEEMMWEKEEKI-RE 381
+E+ R QE+ RR ++ W+ EE+ +R+ ++ K +E++R+ ++++ E+EE++ RE
Sbjct: 859 DQERRRSQEQ--RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE 916
Query: 382 LEEKMHEQEK---IREQEEKRQEEEKI----REQEKRQEQEAKMWRQEEKIREQEEKIRE 434
EK QE+ RE+E+ +QEEE++ RE+ +RQE+E + +R+++K++++EE++
Sbjct: 917 EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE-RQYRKDKKLQQKEEQLLG 975
Query: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW----RQKEKMHEQEKI 490
+E + R++E+ ++K REEE+ Q++EE +EE+ + + + W R+K+++ ++E+
Sbjct: 976 EEPEKRRRQER---EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
Query: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE--EKIREQEEMMQE 548
+EE R++ ++ ++E + RE+EE +E+ + E+ E R QE + R++EE+ QE
Sbjct: 1033 LLREE---REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE 1089
Query: 549 QEEKMGEQEEKMQEQEKMR--RQEEKIREQEEK-IREQKEKIREQE-EKIWEQEEKIREQ 604
+E+ + E+ EK + QE+ R R+EE+++++EE+ +RE++EK R QE E+ + +EE+++++
Sbjct: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149
Query: 605 EEMM----------QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654
EE + QE E + E+EE E+E+ ++E++EK R++ E+ + +E L++Q+
Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Query: 655 EKMQEHQE 662
K + E
Sbjct: 1210 RKQRYRDE 1217
Score = 235 bits (600), Expect = 9e-62
Identities = 188/739 (25%), Positives = 372/739 (50%), Gaps = 131/739 (17%)
Query: 38 HLPTHPHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPE 97
H H + +E + + +E+ T+ H Q + +K+++ E
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQ----------ERRKQQLKRDQEEE 483
Query: 98 TTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE 157
E+ ++ + ++ LRRE E + ++ LQ L Q ++ E
Sbjct: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Query: 158 GEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 217
L+ R + LEQ ++++ +R + L +E + L R E
Sbjct: 544 ERREQLLKREEEK-----RLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE---QE 595
Query: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
E E+ K +E +L + E+ E +L +E + + R +LL ++Q + L +E Q
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEE-RRQQLLKSEEQEERRQQQLRREQQER 654
Query: 278 -SAKLQAQVEENELWNRLNQQQEEKMWRQE--------------EKIQEWEEKIQEQEE- 321
+L+ + EE L RL ++ EE+ QE +I +W+ +++ + +
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 322 ---------KIREQEEKIREQEEKMRRQE-EMMWEKEEKMRRQEE---------MMWEKE 362
+ +E + + +EQEEK RR+E E+ W++EE+ RQ++ W+ E
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE 774
Query: 363 EKMRRLEEMMW-------EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK----- 410
EK R + + ++E ++R E + EQ + E+EEK Q + RE+EK
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFL 834
Query: 411 -------RQEQEAKMWRQEEKIREQEEKIREQEKKM---WR------------------- 441
R+E+ ++ +E+ ++E +E+ R QE++ WR
Sbjct: 835 EEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPA 894
Query: 442 ------------QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW----RQKEKMH 485
QEE+ Q + RE+ +RQEQE +R+EE+++++EE R+K +
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954
Query: 486 EQEKIRKQEEKVWRQEEKM--HDQEEKIREQEEKMWRQEEKIREQEEKI-REQEEKIREQ 542
E+E+ ++++K+ ++EE++ + E++ R++ EK +R+EE+++++EE++ RE+ EK R Q
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 543 E---------EMMQEQEEKMGEQEEK--MQEQEKMRRQEEKIREQEEK-IREQKEKIREQ 590
E E+ QE+E+ + E+ EK +QE+E+ R+EE+++++EE+ + E++E R Q
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 591 E-EKIWEQEEKIREQEEMM--QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE-EKMWEQ 646
E E+ + +EE+++++EE + +E E++ ++ E+ C +EE++Q++EE++ R+E EK Q
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 647 EV-RLRQQEEKMQEHQEHL 664
E+ R ++EE++Q+ +E L
Sbjct: 1135 ELERQYREEEEVQQEEEQL 1153
Score = 235 bits (600), Expect = 9e-62
Identities = 173/600 (28%), Positives = 334/600 (55%), Gaps = 98/600 (16%)
Query: 107 PEDEQKASHQHQEALRRELEAQVHTIRILT-CQKTELQMALYYSQHAVKQLEGEARDLIS 165
PE+E+K + Q RRE E ++ + Q+ E L + +++ + R
Sbjct: 812 PEEEEKEQRRRQ---RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868
Query: 166 RLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
R W++ +L +ER LY E+L+++
Sbjct: 869 RRDQKWRW-----------------------QLEEERKRRRHTLYAKPALQEQLRKEQ-- 903
Query: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
QL++ E+ E+Q +E +R+ E+ + ++QLQ E + L +E
Sbjct: 904 -----QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE------------ 946
Query: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR---EQEEKIREQEEKMRRQEE 342
E E + +Q+ E+ +R+++K+Q+ EE++ +E + R E+E+K RE+EE + +E+
Sbjct: 947 -ERE---KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK---IREQEEKR 399
++ E+ EK RRQE WE++ R+ +E+ E+E+ +RE EK QE+ RE+EE +
Sbjct: 1003 LLREEREKRRRQE---WERQ--YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQ 1057
Query: 400 QEEEKI----REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ--EEKIHEQEKIR 453
QEEE++ RE +RQE E + ++EE +E+E+ +RE+ +K RQ E + E+E+++
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Query: 454 EEEK---RQEQEEMWRQ--EEKIREQEEIWRQKEKM--HEQEKIRKQE-EKVWRQEEKMH 505
+EE+ R+E+E+ RQ E + RE+EE+ +++E++ E EK R+QE E+ +R+EE++
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177
Query: 506 DQEEKI--------REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE 557
+EE++ R++ E+ +R+EE+++ Q+ K R ++E R + E E++ ++
Sbjct: 1178 QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
Query: 558 EKM----QEQEKMRRQEE-KIREQEEK------IREQKEKIREQEEKIWEQEEKIREQEE 606
K+ +E E+ R+ E+ ++R+++ + + EQ+E+ REQE + W+Q ++ +EE
Sbjct: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
Query: 607 MMQEQEEKMWEQEEKMCEQEEKM--QEQEEKMRRQE--EKMWEQEVRLRQQEEKMQEHQE 662
++ +E+K ++ ++ ++E+++ +E+EEK RRQE K E+E L+++EE+ QE
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
Score = 227 bits (579), Expect = 2e-59
Identities = 153/502 (30%), Positives = 313/502 (62%), Gaps = 57/502 (11%)
Query: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
E E+ L+ Q +K +R + + RD EL+R +E +E+ A+ +E+LQ +
Sbjct: 143 EQERELAEGEEQSEKQERLEQRDRQRRDE---ELWRQRQEWQEREERRAE-EEQLQSCKG 198
Query: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
++E + ++L+R+ +LL E G+E + Q + E +R+
Sbjct: 199 HETEEFPDEEQLRRR----ELL--------ELRRKGRE--------EKQQQRRERQDRVF 238
Query: 296 QQQEEKMWRQEEKI-QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Q++EEK WR+ E + ++ EEK+QE+E +++ +++E+EE++R+ E +++RR+
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEP---QRQRELQEEEEQLRKLER------QELRRE 289
Query: 355 EEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 414
+ ++++++RR +++ ++EE+ RE +E+ EQ++ REQ+E+R+E++ REQE+R+EQ
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 415 EAKMWRQEEK-----IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 469
+ + ++EE+ REQEE+ REQ+ + R+++ EQ+ RE++ R+EQ+ R+E+
Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLR--REQQLRREQQLRREQQLRREQQ--LRREQ 405
Query: 470 KIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKI-REQEEKM-WRQEEKIRE 527
++R ++++ R+++ EQ+ R+QEE+ Q+ + +E+++ REQEE+ W + E+ E
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Query: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
+ E+ R +++ R+QEE +E+ K+ E+EE+ ++QE R+E+++R ++E+ REQ+ K
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKL-EEEERREQQE---RREQQLRREQEERREQRLKR 521
Query: 588 REQEEKIWEQEEKIREQEEMMQEQEEK----MWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643
+E+EE++ ++++R ++++ +EQEE+ + +EEK EQE + Q + + + +++
Sbjct: 522 QEEEERL---QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
Query: 644 WEQEVRLRQQEEKMQEHQEHLE 665
++E RQQ K +E +E LE
Sbjct: 579 LKREEERRQQRLK-REQEERLE 599
Score = 218 bits (555), Expect = 1e-56
Identities = 157/579 (27%), Positives = 324/579 (55%), Gaps = 53/579 (9%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVK-QLEGEARDLISR 166
E E++ + ++ R E E Q ++L ++ + + + Q+ K +L+ E L+
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Query: 167 LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 226
+ + ++++ R EEL +E + L E R T +EL+ + K
Sbjct: 1037 EREKRRLQ------------ERERQYREEEELQQEEEQLLGE-ERETRRRQELERQYRKE 1083
Query: 227 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK--LQAQ 284
+E ++ E+ ++ E +R+ ER + +++LQ E + L +E + + L+ Q
Sbjct: 1084 EE----LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
Query: 285 VEENELWNRLNQQQEEKMWRQE---EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
E E QQ+EE++ R+E + QE E + +E+EE +E+E+ +RE++EK R++
Sbjct: 1140 YREEEEV----QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Query: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ- 400
E + +EE+++RQ+ ++E R + WE E++ + K++ K RE E+ RQ
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYC--KGRENEQFRQL 1253
Query: 401 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK---IREEEK 457
E+ ++R+++ +Q+ + + Q+E+ REQE + +Q + + +EE++ +E+ R + K
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
Query: 458 RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE- 516
QE++++ R+E + + + + +K + EQ ++E+ + RQE +EE++R QE+
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Query: 517 -KMWRQEEKIR--EQEEKIREQEEKIREQE---EMMQEQEEKMGEQEEKMQEQEKMRRQE 570
K +E+++R E+E K ++E+++R QE ++ Q+++ K E+E+++ QE+ +
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER----D 1429
Query: 571 EKIREQEEKIR--EQKEKIREQEEKI-WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
K RE+E+++R E++ K E+E+++ E+ K RE+E+++QE+EE+ ++E+ +
Sbjct: 1430 RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQER----DR 1485
Query: 628 KMQEQEEKMRRQE--EKMWEQEVRLRQQEEKMQEHQEHL 664
K E+E+++RRQE K EQE+R ++ E K E ++ L
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Score = 216 bits (550), Expect = 5e-56
Identities = 173/583 (29%), Positives = 333/583 (57%), Gaps = 47/583 (8%)
Query: 111 QKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDS 170
Q+ + E R+LE + R Q+ E ++A Q + KQ E RD R +
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ-SEKQERLEQRDRQRRDEEL 173
Query: 171 WKFAGELEQALSAVATQKKKAD---RYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
W+ E ++ A +++ EE E EL E K++ + +
Sbjct: 174 WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
Query: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ--LQAEADHLGK-ELQSVSAKLQAQ 284
+ E E+ E + L+++ E+ + PQ+Q LQ E + L K E Q + + Q +
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 285 VEENELWNR---LNQQQEEKMWRQEEKIQEWEEKIQEQEEKI-----REQEEK----IRE 332
++ + R L ++QEE+ Q+E+ +E +E+ ++QEE+ REQEE+ +R
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 333 QEEKMRRQEEMMWEKEEKMRRQE---EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ 389
++E+ RR++++ E+EE+ R Q+ E +E+++RR +++ +E+++R ++ EQ
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL--RREQQLRREQQLRREQ 411
Query: 390 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 449
+ REQ+ +R+++ + ++E+R EQ+ + R+E++++ ++E+ R+ K+ +E + HEQ
Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR--EEETERHEQ 469
Query: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE 509
E+ R+++ +++QEE R+E ++ +EE R++++ EQ+ R+QEE R+E+++ QEE
Sbjct: 470 ER-RKQQLKRDQEEE-RRERWLKLEEEERREQQERREQQLRREQEE---RREQRLKRQEE 524
Query: 510 KIREQEEKMWRQEEKIREQEEKIREQ-----EEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
+ R Q+ R E+++R ++E+ REQ EEK EQE Q + + E+ +++ ++E
Sbjct: 525 EERLQQR--LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
Query: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624
+ RRQ+ REQEE++ EQ+ K RE+ E++ EQEE+ REQ +E EE+ +Q K E
Sbjct: 583 EERRQQRLKREQEERL-EQRLK-REEVERL-EQEER-REQRLKREEPEEERRQQLLKSEE 638
Query: 625 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH--QEHLE 665
QEE+ Q+Q +RR++++ EQ ++ ++EE++++ +EH E
Sbjct: 639 QEERRQQQ---LRREQQERREQRLKREEEEERLEQRLKREHEE 678
Score = 212 bits (540), Expect = 8e-55
Identities = 171/596 (28%), Positives = 327/596 (54%), Gaps = 112/596 (18%)
Query: 176 ELEQALSAVATQKKKADRYIEE----LTKERDALSLELYRNTITDEELKEKNAKLQEKL- 230
E EQ + K+ DR +E L +ER+ E R TD + +E+ LQE+
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREERE----EKRRRQETDRKFREEEQLLQEREE 1350
Query: 231 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQL---QAEADHLGKELQSVSAKLQAQVEE 287
Q + ++ + + +EL+ + + K L +Q+L + E L +E Q + + Q+ +
Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Query: 288 N------ELWNRLNQQQEEKMWRQEE---KIQEWEEKIQEQEEKIR-EQEEKIREQEEKM 337
+ E +L++Q+ ++ +R+EE + QE E K E+E+++R E+ K RE+E+ +
Sbjct: 1411 DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLL 1470
Query: 338 RRQEEMMWEKEEKMRR--QEEMMWEKEEKMRRLEEM---MWEKEEKIRELEEKMHEQEKI 392
+ +EE ++E+ R+ +EE ++E+ R+ E E E K E E+++H Q++
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ 1530
Query: 393 RE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR----EQEKKMWRQEEKIH 447
R+ +E++Q + R Q++RQ+++ K +R+EE++R++ E+ + E+++K +E+K+
Sbjct: 1531 RKFLQEEQQLRRQERGQQRRQDRDRK-FREEEQLRQEREEQQLSRQERDRKFRLEEQKVR 1589
Query: 448 EQE---KIREEE---KRQEQEEMWRQEE--KIREQEEIWRQKEK--MHEQEKIRK---QE 494
QE K E+E +RQE ++ RQE K RE E++ +++E+ +H QE+ RK +E
Sbjct: 1590 RQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEE 1649
Query: 495 EKVWRQEEKM---HDQEEKIREQE-----------------------EKMWRQEEKIR-- 526
++ RQE + HD++ K RE+E E+ R++E+ R
Sbjct: 1650 PQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709
Query: 527 -EQEEKIREQ--EEKIREQEEMMQEQEEKMGEQEE---KMQEQEKMR--RQEEKIREQE- 577
++E+++R Q E K RE+E++ QE E++ ++E K+ E+E++R R+E+++R QE
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 578 -EKIREQKEKIREQEE---KIWEQEEKIREQEEMMQEQEEKM-----------WEQEEKM 622
K RE+++ +E+EE + E + K RE+E++ QE+EE+ WE+E+
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQ 1829
Query: 623 CEQEEKMQEQE--------------EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
E++E+ QE EK RR+E+++W++E + R+QE + + +EH+
Sbjct: 1830 LEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885
Score = 208 bits (530), Expect = 1e-53
Identities = 158/547 (28%), Positives = 311/547 (56%), Gaps = 59/547 (10%)
Query: 156 LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 215
LE E ++ R HD K + + L + + + ++ + K A L + T
Sbjct: 37 LEREFGAVLRRPHDP-KTVDLILELLDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGL 95
Query: 216 DEELKEKNAKLQEKLQLVESEKSEI-QLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
DEE K A+ K L++ + E Q + R+LE P Q+ + + +EL
Sbjct: 96 DEE---KRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEE----PGQRRRQKRQEQEREL 148
Query: 275 QSVSAKLQAQVEENE-LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE--KIREQEEKIR 331
A+ + Q E+ E L R Q+++E++WRQ ++ QE EE+ E+E+ + E +
Sbjct: 149 ----AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
Query: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
EE++RR+E + ++ + +Q++ ++ + EE W K E + EE+ ++E+
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Query: 392 IREQEEKRQEEEKIR---------EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 442
+ Q E ++EEE++R E+++ ++Q+ ++ R+++ R+QEE+ REQ+++ Q
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKI-REQEEIWRQKEKMHEQEKIRKQE----EKV 497
+E+ +QE+ RE++ R+EQEE R+E+++ REQEE R+++ EQE+ R+++ E+
Sbjct: 325 QERREQQEERREQQLRREQEE--RREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Query: 498 WRQEEKMHDQEEKIREQE---------EKMWRQEEKIREQEEKIREQEEKIREQ------ 542
R+E+++ +++ REQ+ E+ R+E+++R +++ REQEE+ EQ
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Query: 543 --EEMMQEQEEKMG--EQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
+ + +EQEE+ ++EE+ + E+ RR+++ R+QEE+ RE+ K+ E+E + EQ+
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR--EQQ 500
Query: 599 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ---EEKMRRQEEKMWEQEVRLRQQEE 655
E R ++++ +EQEE+ EQ K E+EE++Q++ E+++RR++E+ EQ ++ +++
Sbjct: 501 E--RREQQLRREQEERR-EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Query: 656 KMQEHQE 662
QE +E
Sbjct: 558 LEQERRE 564
Score = 208 bits (530), Expect = 1e-53
Identities = 157/481 (32%), Positives = 297/481 (61%), Gaps = 57/481 (11%)
Query: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE----RAKLLLPQQQLQAEADHLG 271
+E+L+E+ + Q +LQ E E+ +L +EL+R+ + + + L +QQL+ + +
Sbjct: 257 EEKLQEEEPQRQRELQ--EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 272 KELQSVSAKLQAQVEENE--LWNRLNQQQEEKMWRQEEKIQEWEEKIQ----EQEEKIRE 325
+E Q + Q + E+ E +L ++QEE+ +Q + QE E + Q EQEE+ RE
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374
Query: 326 QEEKIREQ---EEKMRRQEEMMWE----KEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378
Q+ + +Q E+++RR++++ E +E+++RR++++ +E+++RR +++ E+EE
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL--RREQQLRREQQLRREQEE- 431
Query: 379 IRELEEKMHEQEKIREQEEKRQEEE-----KIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
E E+ HEQE+ REQ KR++EE K E+ +R EQE R+++ R+QEE+ R
Sbjct: 432 --ERHEQKHEQER-REQRLKREQEERRDWLKREEETERHEQER---RKQQLKRDQEEERR 485
Query: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
E+ K+ +EE+ EQ++ RE++ R+EQEE R+E++++ QEE R ++++ ++++R++
Sbjct: 486 ERWLKL--EEEERREQQERREQQLRREQEE--RREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ---EEKIREQEEMMQEQE 550
+E+ R+E+ + +EEK EQE R+E++++ ++E+ R+Q E+ R Q+ + +EQE
Sbjct: 542 QEE--RREQLLKREEEKRLEQE----RREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 551 EKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQE 610
E++ E++++ +E R ++E+ REQ K E +E+ R+Q K EQEE R Q+++ +E
Sbjct: 596 ERL---EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE--RRQQQLRRE 650
Query: 611 QEEKMWEQEEKMCEQEEKMQ-----EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Q+E+ EQ K E+EE+++ E EE+ R QE EQE + + ++ + Q LE
Sbjct: 651 QQERR-EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE 709
Query: 666 A 666
+
Sbjct: 710 S 710
Score = 206 bits (523), Expect = 7e-53
Identities = 169/632 (26%), Positives = 332/632 (52%), Gaps = 101/632 (15%)
Query: 105 HSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI 164
H PE+EQ + +EA RR+ ++Q KQL E R+
Sbjct: 1292 HFPEEEQLEREEQKEAKRRDRKSQEE-----------------------KQLLREEREEK 1328
Query: 165 SRLHDSWKFAGELEQALSAVATQ---KKKADRYI--EELTKERDALSLELYRNTITDEEL 219
R ++ + E EQ L Q +++ DR EEL + + +E
Sbjct: 1329 RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQER 1388
Query: 220 KEKNAKLQEKLQLVESEKS------------EIQLNVKELKRKLERAKLLLPQQQLQA-- 265
+ K K +++L+ E E+ E QL+ +E RK + + +Q+ +
Sbjct: 1389 ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448
Query: 266 --EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI--QEWEEKIQEQEE 321
E L +E + + ++E E Q+++ K +E+++ QE + K +EQE
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508
Query: 322 KIREQEEKIREQEEKMRRQEEM--MWEKEEKMRRQE---EMMWEKEEKMRRLEEMMWEKE 376
+ +E E K E+E+++ RQ+ ++E+++RRQE + +++ K R E++ E+E
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1568
Query: 377 EKIRELEEKMH----EQEKIREQEEKR---QEEEKIREQEK----RQEQEAKMWRQEEKI 425
E+ +E+ E++K+R QE++R ++E+++R QE RQE++ K E+ +
Sbjct: 1569 EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLL 1628
Query: 426 REQEEKI---REQEKKMWRQEEKIHEQE-----------KIREEEK---RQEQEEMWRQE 468
+E+EE+ +E+++K +E ++ QE K REEE+ E++++ RQE
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE 1688
Query: 469 E--KIREQEEIWRQKEK----MHEQEKIRKQE-EKVWRQEEKMH---DQEEKIREQEEKM 518
K RE+E+ R++E+ + E++++R+QE E+ +R+EE++ +QE+ R++ +
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748
Query: 519 WRQEEKIR----EQEEKIREQEEKIREQEEMMQEQEE---KMGEQEEKMQEQEKMR--RQ 569
+EE++R EQ+ + +E++ K RE+E++ QE+EE + E + K +E+E++R R+
Sbjct: 1749 ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Query: 570 EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 629
E+++R Q+ R+ K + E++ ++ EQE+++R++ + EE+ QE+ E++E
Sbjct: 1809 EQQLRPQQ---RDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELW 1865
Query: 630 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
QE+E+K R++ E+ +E RQQ+E+ + Q
Sbjct: 1866 QEEEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
Score = 206 bits (523), Expect = 7e-53
Identities = 157/560 (28%), Positives = 308/560 (55%), Gaps = 61/560 (10%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E E+K + Q+ +E E Q+ R ++ E Q++ ++ E + R R
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR----RQ 1442
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
KF E +Q + ++ + R E+L +ER+ +L+R +E++ K
Sbjct: 1443 ERERKFLEEEQQ----LRQERHRKFREEEQLLQERE--EQQLHR--------QERDRKFL 1488
Query: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQL--QAEADHLGKELQSVSAKLQAQV 285
E+ Q + ++ + + +EL+ + K L +QQL Q +E Q + + + Q
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
Query: 286 EENELWNRLNQQQEEKMWRQEEKI--QEWEEKIQEQEEKIR--EQEEKIREQEEKMRRQE 341
+ + ++++ + R+E+++ QE + K + +E+K+R EQE K E E+++RRQE
Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
Query: 342 ---EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398
++ E++ K R E+++ E+EE+ +E ++ K E E ++ QE REQ+ +
Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQE----RDRKFLEEEPQLRRQE--REQQLR 1662
Query: 399 RQEEEKIREQEKR----QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 454
+ K RE+E+ +EQ+ + ++ K RE+E+++R QE R+ + + E++++R
Sbjct: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE----RERKFLQEEQQLR- 1717
Query: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK--QEEKVW--RQEEKMHDQEEK 510
RQE E +R+EE++R++ E +E++ QE+ RK +EE++ R+E+++ QE
Sbjct: 1718 ---RQELERKFREEEQLRQETE----QEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 511 IREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE 570
+ +EE+ RQE + EQ+ + +E + K RE+E++ QE+EE +Q Q K R +E
Sbjct: 1771 RKFREEEQLRQERE--EQQLRSQESDRKFREEEQLRQEREE---QQLRPQQRDGKYRWEE 1825
Query: 571 EKIR--EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK-MWEQEEKMCEQEE 627
E+++ EQE+++R+++++ EE+ QE+ RE++E+ QE+E+K E+E K+ E+
Sbjct: 1826 EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885
Query: 628 KMQEQEEKMRRQEEKMWEQE 647
+ Q++EE+ RQ ++ QE
Sbjct: 1886 RRQQKEEQRHRQVGEIKSQE 1905
Score = 202 bits (514), Expect = 8e-52
Identities = 170/623 (27%), Positives = 332/623 (53%), Gaps = 85/623 (13%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMA-------LYYSQHAVKQ----- 155
++E++ + QE R+E E Q L QK + + L + K+
Sbjct: 1178 QEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRD 1237
Query: 156 ----LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELT-KERDA-LSLEL 209
+G + +L DS + +Q L + ++++ DR E ++RD E
Sbjct: 1238 NKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
Query: 210 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269
+E K ++ K QE+ QL+ E+ +E +R+ E + ++QL E +
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREER-------EEKRRRQETDRKFREEEQLLQEREE 1350
Query: 270 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI----QEWEEKIQEQEEKIRE 325
Q K + + ++ R ++E+++ RQE + +E + + QE+E+++R+
Sbjct: 1351 QPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Query: 326 -QEEKIREQEEKMRRQEE--MMWEKEEKMRRQEE--MMWEKEEKMRRLEEMMWEKEEKIR 380
++ K RE+E+++ RQE E+E+++RRQE E+E+++R+ + +EE++
Sbjct: 1411 DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL- 1469
Query: 381 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
L+E+ +Q +E++ K EEE +Q +RQE++ K QE + +E E K E+E+++
Sbjct: 1470 -LQEREEQQLHRQERDRKFLEEE---QQLRRQERDRKFREQELRSQEPERKFLEEEQQLH 1525
Query: 441 RQEEK---IHEQEKIREEEK----RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
RQ+ + + E++++R +E+ RQ+++ +R+EE++R++ E +Q + K R +
Sbjct: 1526 RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE-EQQLSRQERDRKFRLE 1584
Query: 494 EEKVWRQEEK---MHDQEEKIREQEEKMWRQE--EKIREQEEKIREQEE----------K 538
E+KV RQE++ M D+++ R++ ++ RQE K RE E+ ++E+EE K
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Query: 539 IREQEEMMQEQE----------EKMGEQEEKMQ--EQEKMRRQE--EKIREQEEKIREQK 584
E+E ++ QE K E+E+ +Q E++++RRQE K RE+E+++R Q+
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704
Query: 585 EKIR----EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE---KMCEQEEKMQEQEE-KM 636
+ + EQ+ + E E K RE+E++ QE E++ ++E K+ E+E+ E+EE ++
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQL 1764
Query: 637 RRQE-EKMWEQEVRLRQQEEKMQ 658
RRQE ++ + +E +LRQ+ E+ Q
Sbjct: 1765 RRQERDRKFREEEQLRQEREEQQ 1787
Score = 201 bits (512), Expect = 1e-51
Identities = 181/612 (29%), Positives = 341/612 (55%), Gaps = 89/612 (14%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E+EQ + ++ R+ELE Q L ++ +L + ++ + + + R
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Query: 168 HDSWKFAGELEQA--LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAK 225
++ E +++ +K+ A R + K R+ E +R + D +L+++ +
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGREN---EQFRQ-LEDSQLRDRQS- 1263
Query: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Q+ LQ + E+ E +E +R +R + ++QL+ E KE + K Q
Sbjct: 1264 -QQDLQHLLGEQQERDRE-QERRRWQQRDRHFPEEEQLEREEQ---KEAKRRDRKSQ--- 1315
Query: 286 EENELWNRLNQQQEEKMWRQE--EKIQEWEEKIQEQEEK-IREQEEKIREQEEKMRRQEE 342
EE +L L +++EEK RQE K +E E+ +QE+EE+ +R QE + +EE++R QE+
Sbjct: 1316 EEKQL---LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQ 1372
Query: 343 --MMWEKEEKMRRQE-EMMWEKEEKMRRLEE----MMWEKEEKIRELEEKMHEQEKIREQ 395
E+E+++RRQE E + KEE+ R +E + +++ K RE E+++ QE+ R+
Sbjct: 1373 GRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKF 1432
Query: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIR-EQEEKIREQEKKMW-RQEEKIHEQEKIR 453
R+EE+++R RQE+E K +E+++R E+ K RE+E+ + R+E+++H QE+ R
Sbjct: 1433 ---REEEQQVR----RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR 1485
Query: 454 ---EEE---KRQEQEEMWRQEEKIREQE---EIWRQKEKMHEQEKIRK---QEEKVWRQE 501
EEE +RQE++ +R++E +R QE + +++++H Q++ RK +E+++ RQE
Sbjct: 1486 KFLEEEQQLRRQERDRKFREQE-LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544
Query: 502 ---EKMHDQEEKIREQEE-----------------KMWRQEEKIR--EQEEKIREQEEKI 539
++ D++ K RE+E+ K +E+K+R EQE K E E+++
Sbjct: 1545 RGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL 1604
Query: 540 REQE---EMMQEQEEKMGEQEEKMQEQE--KMRRQE--EKIREQEEKIREQKEKIREQEE 592
R QE ++ QE++ K E E+ +QE+E ++ RQE K E+E ++R Q+ REQ+
Sbjct: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE---REQQL 1661
Query: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ--EEKMWEQEVRL 650
+ +++ K RE+E+++QE EE+ ++E+ + K +E+E+++RRQ E K ++E +L
Sbjct: 1662 R-HDRDRKFREEEQLLQEGEEQQLRRQER----DRKFREEEQQLRRQERERKFLQEEQQL 1716
Query: 651 RQQEEKMQEHQE 662
R+QE + + +E
Sbjct: 1717 RRQELERKFREE 1728
Score = 197 bits (502), Expect = 2e-50
Identities = 152/618 (24%), Positives = 331/618 (53%), Gaps = 84/618 (13%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E +++ Q +E R+LE Q +R ++ + Q L Q ++ E E R+
Sbjct: 264 EPQRQRELQEEEEQLRKLERQ--ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
+ + + E+ ++++ +R ++L +E++ E +EE +E+ + +
Sbjct: 322 REQQERREQQEERREQ-QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Query: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
++L+ + + E QL ++ +L R + L +QQL+ E ++L+ + Q EE
Sbjct: 381 QQLRREQQLRREQQLRREQ---QLRREQQLRREQQLRRE-----QQLRREQQLRREQEEE 432
Query: 288 NELWNRLNQQQEEKMWRQEEKIQEW---EEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
+++E+++ R++E+ ++W EE+ + E++ R+Q+ K R+QEE+ RR+ +
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK-RDQEEE-RRERWLK 490
Query: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404
E+EE+ +QE +E+++RR +E +E++++ EE+ Q+++R +++ R+E+E+
Sbjct: 491 LEEEERREQQER----REQQLRREQEE--RREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Query: 405 IREQEKRQEQEAKM--WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ- 461
REQ ++E+E ++ R+E++++ ++E+ R+Q + ++EE+ +Q RE+E+R EQ
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQ---LLKREEERRQQRLKREQEERLEQR 601
Query: 462 ---EEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKM 518
EE+ R E++ R ++ + R++ + ++++ K EE+ R+++++ ++++ REQ K
Sbjct: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK- 660
Query: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEE--------------------------- 551
R+EE+ R ++ RE EE+ REQE +EQE+
Sbjct: 661 -REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV 719
Query: 552 -----KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI---WEQEEK--- 600
K Q + +++EK RR+E +++ QEE+ ++++ EQ W+ EEK
Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER 779
Query: 601 ----------IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW---EQE 647
+REQ E EE+ ++ + E+EEK Q + ++ R++E + E++
Sbjct: 780 GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 648 VRLRQQEEKMQEHQEHLE 665
++ R++ +++QE ++ L+
Sbjct: 840 LQRRERAQQLQEEEDGLQ 857
Score = 197 bits (502), Expect = 2e-50
Identities = 158/608 (25%), Positives = 323/608 (53%), Gaps = 120/608 (19%)
Query: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAG 175
+ ++ LRRE E + H QK E + + +K+ + E RD + R +
Sbjct: 420 RREQQLRREQEEERHE------QKHEQERR----EQRLKREQEERRDWLKREEE------ 463
Query: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
T++ + +R ++L ++++ EE +E+ KL+E+ + +
Sbjct: 464 ----------TERHEQERRKQQLKRDQE-------------EERRERWLKLEEEERREQQ 500
Query: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
E+ E QL ++ +R+ +R K +++LQ Q + ++ Q + E+ E +L
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQ----------QRLRSEQQLRREQEERREQLL 550
Query: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
+++EEK QE + Q + + +E+ +++ ++EE+ R+Q K R QEE + E++++R+E
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK-REQEERL---EQRLKREE 606
Query: 356 EMMWEKEEKMRRLEEMMWEKEEKIREL-----EEKMHEQEKIREQEEKRQEEEKIREQEK 410
E+EE+ + + +EE+ ++L +E+ +Q+ REQ+E+R++ K E+E+
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 411 RQEQEAKMWRQEEKIREQEEKIREQE-----------KKMWR-------QEEKIHEQEKI 452
R EQ K +EE+ REQE EQE K W+ ++ K++ + +
Sbjct: 667 RLEQRLKREHEEER-REQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725
Query: 453 RE-EEKRQEQEE---------MWRQEEKIREQEE--------IW---------RQKEKMH 485
+E + +RQEQEE W++EE+ Q++ W R ++++
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK-MWRQEEKIREQEEKIREQEEKI--REQ 542
+ +R+Q E+ R EE+ ++ + E+EEK R++ + RE+E + E+EE++ RE+
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRER 845
Query: 543 EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ---------KEKIREQEEK 593
+ +QE+E+ + E +E+ + QE+ R Q+ + + +EE+ R + +E++R++++
Sbjct: 846 AQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL 905
Query: 594 IWEQEEKIREQE---EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE-EKMWEQEVR 649
+ E+EE+++ +E QEQE + E+E+ E+E+ ++E+ EK RRQE E+ + ++ +
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 650 LRQQEEKM 657
L+Q+EE++
Sbjct: 966 LQQKEEQL 973
Score = 193 bits (490), Expect = 5e-49
Identities = 153/569 (26%), Positives = 307/569 (53%), Gaps = 85/569 (14%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E+EQ + ++ R+ELE Q ++ E+Q Q ++ E R + R
Sbjct: 1119 EEEQLLREEREKRRRQELERQYR-------EEEEVQQE--EEQLLREEPEKRRRQELERQ 1169
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
+ + + E+ L +K++ +R E +E + L + + DE+ + + K Q
Sbjct: 1170 YREEEELQQEEEQLLREEQEKRRQER--ERQYREEEELQRQKRKQRYRDED-QRSDLKWQ 1226
Query: 228 ---EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
EK V K + E R+LE ++L +Q Q + HL E Q
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR--DRQSQQDLQHLLGEQQE-------- 1276
Query: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
+++QE + W+Q ++ EE+++ +E+K ++ ++ ++E+++ R+E
Sbjct: 1277 ---------RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE--- 1324
Query: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI--RELEEKMHEQEKIREQEEKR--- 399
+EEK RRQE + K R E+++ E+EE+ R+ ++ +E++R QE+ R
Sbjct: 1325 --REEKRRRQET-----DRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFL 1377
Query: 400 QEEEKIREQEKRQEQEAKMWRQEEKIR--EQEEKIREQEKKMWRQEEKIHEQEKIREEEK 457
+EE+++R RQE+E K ++E+++R E+E+++R+ + +R+EE Q+ R+E
Sbjct: 1378 EEEQRLR----RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE----QQLSRQERD 1429
Query: 458 RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK 517
R+ +EE E+++R QE R+++ + E++++R++ + +R+EE++ + E E++
Sbjct: 1430 RKFREE----EQQVRRQE---RERKFLEEEQQLRQERHRKFREEEQLLQERE-----EQQ 1477
Query: 518 MWRQEE--KIREQEEKIREQEE--KIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
+ RQE K E+E+++R QE K REQE QE E K E+E+++ Q++ R K
Sbjct: 1478 LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR----KF 1533
Query: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633
++E+++R Q+ + ++++ + K RE+E++ QE+EE+ ++E+ +++ +++EQ+
Sbjct: 1534 LQEEQQLRRQERGQQRRQDR----DRKFREEEQLRQEREEQQLSRQER--DRKFRLEEQK 1587
Query: 634 EKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
+ + QE K E E +LR+QE + Q QE
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQE 1616
Score = 191 bits (485), Expect = 2e-48
Identities = 152/596 (25%), Positives = 312/596 (52%), Gaps = 52/596 (8%)
Query: 109 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 168
++Q+ + QE ++ E + +R ++ E Q+ +Q E + R
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRR-------EQEEERREQQLRREQ 368
Query: 169 DSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE 228
+ + +L + Q+ + ++ + + R L + +++L+ + +E
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Query: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 288
+ + +K E + + LKR+ E + L +++ E + +E + K + E
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREE---ETERHEQERRKQQLKRDQEEERR 485
Query: 289 ELWNRLNQQQE-EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ---EEKMRRQEEMM 344
E W +L +++ E+ R+E++++ +E+ +EQ K +E+EE+++++ E+++RR++E
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE- 544
Query: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE------K 398
+E+ ++R+EE E+E + +RL+ E+ +++ + EE+ +Q REQEE K
Sbjct: 545 -RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603
Query: 399 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE-K 457
R+E E++ EQE+R+EQ K EE+ R+Q K EQE++ RQ++ EQ++ RE+ K
Sbjct: 604 REEVERL-EQEERREQRLKREEPEEERRQQLLKSEEQEER--RQQQLRREQQERREQRLK 660
Query: 458 RQEQEEMWRQ------EEKIREQEEIWRQKEKMHEQEKIR-------------KQEEKVW 498
R+E+EE Q EE+ REQE ++E+ E+ K R ++ KV+
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVY 720
Query: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI---REQEEKIREQEEMMQEQEEKMGE 555
+ K Q + +EQEEK R+E +++ QEE+ ++QEE+ R + EEK
Sbjct: 721 SRPRKQEGQRRR-QEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER 779
Query: 556 QEEKMQEQEKMRRQEEK-IREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
+++ + +R Q E+ +R +E + REQ+ E+E++ ++ + RE+E E+EE+
Sbjct: 780 GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 615 MWEQE--EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
+ +E +++ E+E+ +QE +E+ R QE++ ++ ++E K + H + + A+
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPAL 895
Score = 167 bits (423), Expect = 3e-41
Identities = 109/337 (32%), Positives = 209/337 (62%), Gaps = 40/337 (11%)
Query: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 411
RRQEE E + R+LEE E R +++ ++ ++ E EE+ +++E++ EQ R
Sbjct: 113 RRQEEDQRRFEPRDRQLEE-----EPGQRRRQKRQEQERELAEGEEQSEKQERL-EQRDR 166
Query: 412 QEQEAKMWRQEEKIREQEEKIREQEK---------------KMWRQEEKIHEQEKIREEE 456
Q ++ ++WRQ ++ +E+EE+ E+E+ + R+ E + + K REE+
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226
Query: 457 KRQEQEEMWRQEEKIREQEE-IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE--KIRE 513
++Q +E RQ+ +E+EE WR++E + +E+ + QEE+ RQ E ++E+ K+
Sbjct: 227 QQQRRE---RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
QE + RQEE+ +Q++++R +++ R+QEE +EQ+E+ EQ+E+ ++QE+ R+E+++
Sbjct: 284 QELRRERQEEE--QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE--RREQQL 339
Query: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE---EKMWEQEEKMCEQEEKMQ 630
R ++E+ REQ+ + REQEE+ EQ+ + REQEE +EQ+ E+ +E+++ +++ +
Sbjct: 340 RREQEERREQQLR-REQEEERREQQLR-REQEEERREQQLRREQQLRREQQLRREQQLRR 397
Query: 631 EQ----EEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 663
EQ E+++RR+++ EQ++R QQ + QE + H
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Score = 149 bits (376), Expect = 8e-36
Identities = 138/509 (27%), Positives = 269/509 (52%), Gaps = 76/509 (14%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTI---RILTCQKTELQMALYYSQHAVKQLEGEARDL- 163
E+EQ+ S Q ++ RE E QV R ++ +L+ + +QL E +
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477
Query: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223
+ R KF E +Q ++++ DR +E++ S E R + +E+ +
Sbjct: 1478 LHRQERDRKFLEEEQQL------RRQERDRKF----REQELRSQEPERKFLEEEQQLHRQ 1527
Query: 224 AK----LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 279
+ LQE+ QL E+ + + ++ K + E +L +++ Q ++ +
Sbjct: 1528 QRQRKFLQEEQQLRRQERGQQRRQDRDRKFR-EEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 280 KLQAQVEENELWN---RLNQQQEEKMWRQEE--KIQEWEEKIQEQEEKI---REQEEKIR 331
K++ Q +E + +L +Q+ ++ RQE K +E E+ +QE+EE+ +E++ K
Sbjct: 1587 KVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFL 1646
Query: 332 EQEEKMRRQE---EMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHE 388
E+E ++RRQE ++ +++ K R +E+++ E EE+ R +E ++ K RE E+++
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE----RDRKFREEEQQLRR 1702
Query: 389 QEKIR-----EQEEKRQE-EEKIREQEK-RQEQEAKMWRQEEKIRE--QEEKIR-EQEKK 438
QE+ R EQ+ +RQE E K RE+E+ RQE E + R++E+ R+ +EE++R E+E++
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762
Query: 439 MWRQEE---KIHEQEKIREEEKRQ-----EQEEMWRQEEKIREQEEI------------- 477
R++E K E+E++R+E + Q E + +R+EE++R++ E
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822
Query: 478 WRQKE-KMHEQE-KIRKQEEKVWRQEEKMHDQEEKIRE-----QEEKMWRQEEKIREQEE 530
W +++ ++ EQE ++R++ ++ +R EE+ QE+ RE QEE+ R++E+ E
Sbjct: 1823 WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER----ER 1878
Query: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEK 559
K+RE+ + +++EE Q ++ QE K
Sbjct: 1879 KLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 109 bits (273), Expect = 7e-24
Identities = 67/255 (26%), Positives = 152/255 (59%), Gaps = 23/255 (9%)
Query: 412 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471
+E+ A+ +E ++++ ++ E +++ ++ ++ E+ R +KRQEQE ++
Sbjct: 97 EEKRARCDGKESLLQDRRQE--EDQRRFEPRDRQLEEEPGQRRRQKRQEQER------EL 148
Query: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK 531
E EE ++E++ ++++ R+ EE +WRQ ++ ++EE+ E+E+ Q K E EE
Sbjct: 149 AEGEEQSEKQERLEQRDRQRRDEE-LWRQRQEWQEREERRAEEEQL---QSCKGHETEEF 204
Query: 532 IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI-REQ 590
E++ + RE E+ ++ E+ ++Q++ RQ+ +E+EEK ++E + R++
Sbjct: 205 PDEEQLRRRELLELRRKGREE--------KQQQRRERQDRVFQEEEEKEWRKRETVLRKE 256
Query: 591 EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 650
EEK+ QEE+ + Q E+ +E+E+ + +++ + ++ ++Q++++RR+++ +QE
Sbjct: 257 EEKL--QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 651 RQQEEKMQEHQEHLE 665
R+Q+E+ +E QE E
Sbjct: 315 REQQEERREQQERRE 329
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 233 bits (595), Expect = 3e-61
Identities = 178/570 (31%), Positives = 300/570 (52%), Gaps = 40/570 (7%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
E+E+K HQ Q ALR +L+ + TI IL +K ELQ AL ++QHA +Q EGE+ DL SRL
Sbjct: 199 EEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALAHTQHAARQKEGESEDLASRL 258
Query: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
S + GELE+ALSAV+TQ+KKADRY +ELTKERDAL LELY+NT ++E+LK++ ++L+
Sbjct: 259 QYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYKNTQSNEDLKQEKSELE 318
Query: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE 287
EKL+++ +EK+ +QLN++EL++KLE +LLL Q + EA ++LQ QA E
Sbjct: 319 EKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDANQQLQ------QAMEER 372
Query: 288 NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK 347
+L L Q E Q E+ ++ E ++ + R++ +++ EQ +R EK
Sbjct: 373 AQLEAHLGQVMESVRQLQMER-DKYAENLKGESAMWRQRMQQMSEQVHTLRE------EK 425
Query: 348 EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 407
E M R +E+ E + L M E EQ+ E E R+E E +
Sbjct: 426 ECSMSRVQEL----ETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELEGLAG 481
Query: 408 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 467
Q + Q Q+ + + REQEE++ E E R E EQ + R + Q +
Sbjct: 482 QLQAQVQDNEGLSRLN--REQEERLLELE----RAAELWGEQAEARRQILETMQNDRTTI 535
Query: 468 EEKIREQEEIWRQKEKMHE-QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR 526
+ + E+ KE++ E Q K + + ++ RE +K+ +EK+
Sbjct: 536 SRALSQNREL---KEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLS 592
Query: 527 EQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK 586
E +E + E K +E + + Q++++ +G ++ + +++ ++E + Q + ++
Sbjct: 593 ELKETV---ELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQ 649
Query: 587 IREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ--------EQEEKMRR 638
+++QE + E R++ + QE+ E +Q +++ Q M ++EE+
Sbjct: 650 LQQQEAQGKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPGEGDGLDREEEEDE 709
Query: 639 QEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
+EE+ E+ V + Q + E E EA +
Sbjct: 710 EEEE--EEAVAVPQPMPSIPEDLESREAMV 737
Score = 145 bits (366), Expect = 1e-34
Identities = 159/667 (23%), Positives = 281/667 (42%), Gaps = 88/667 (13%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP P MS+ETRQSKLA AK++L ++ + +P V T A KKKKI NG+NPETTTSG
Sbjct: 5 PRLPPRPAMSEETRQSKLAAAKKKLREYQQRNSPGVPTGAK--KKKKIKNGSNPETTTSG 62
Query: 103 GCHSPEDEQK-----------------------------ASHQHQEALRRELEAQVHTIR 133
GCHSPED K AS H L + T
Sbjct: 63 GCHSPEDTPKDNAATLQPSDDTVLPGGVPSPGASLTSMAASQNHDADNVPNLMDETKTFS 122
Query: 134 ILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADR 193
+ Q + + GE + L D +L AL + K+ +
Sbjct: 123 STESLRQLSQQLNGLVCESATCVNGEGPASSANLKDLESRYQQLAVALDSSYVTNKQLNI 182
Query: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
IE+L ++ ITD+ +EK Q++ L + ++Q++++ +
Sbjct: 183 TIEKLKQQNQE---------ITDQLEEEKKECHQKQGAL----REQLQVHIQTI------ 223
Query: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
L+ + +LQ H + A Q + E +L +RL + R+ +++
Sbjct: 224 GILVSEKAELQTALAH------TQHAARQKEGESEDLASRLQYSR-----RRVGELERAL 272
Query: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
+ Q++K +++ ++ + +R + + E +++++ E EEK+R L
Sbjct: 273 SAVSTQQKKADRYNKELTKERDALRLELYKNTQSNEDLKQEKS---ELEEKLRVLVTEKA 329
Query: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ-----EKRQEQEAKMWRQEEKIRE- 427
+ + EL++K+ E + +Q R E +Q E+R + EA + + E +R+
Sbjct: 330 GMQLNLEELQKKLEMTELLLQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMESVRQL 389
Query: 428 --QEEKIREQ---EKKMWRQE-EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 481
+ +K E E MWRQ +++ EQ EEK + E + E +
Sbjct: 390 QMERDKYAENLKGESAMWRQRMQQMSEQVHTLREEKECSMSRVQELETSLAELRNQMAEP 449
Query: 482 EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541
+ E+++ + E + + E + Q + + E + REQEE++ E
Sbjct: 450 PPPEPPAGPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDNEGLSRLN---REQEERLLE 506
Query: 542 QEEMMQEQEEKMGEQ-EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK 600
++ E GEQ E + Q E M+ I + RE KE++ E + + +
Sbjct: 507 ----LERAAELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNE 562
Query: 601 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660
E +Q ++ E +K+ E +EK+ E +E + E ++ L+QQ ++ H
Sbjct: 563 NMEITSALQSEQHVKRELGKKLGELQEKLSELKETV----ELKSQEAQSLQQQRDQYLGH 618
Query: 661 QEHLEAA 667
+ AA
Sbjct: 619 LQQYVAA 625
Score = 113 bits (283), Expect = 5e-25
Identities = 128/597 (21%), Positives = 263/597 (44%), Gaps = 99/597 (16%)
Query: 116 QHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLE---------GEARDLISR 166
Q E L++E +R+L +K +Q+ L Q ++ E EA D +
Sbjct: 305 QSNEDLKQEKSELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDANQQ 364
Query: 167 LHDSWKFAGELE----QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
L + + +LE Q + +V + + D+Y E L E ++R + +++ E+
Sbjct: 365 LQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGES-----AMWRQRM--QQMSEQ 417
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP-------QQQLQAEADHLGKELQ 275
L+E+ + S E++ ++ EL+ ++ P +QQLQAEA+HL KEL+
Sbjct: 418 VHTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQLQAEAEHLRKELE 477
Query: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI------------ 323
++ +LQAQV++NE +RLN++QEE++ E + W E+ + + + +
Sbjct: 478 GLAGQLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISR 537
Query: 324 -----REQEEKIREQE--------EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEE 370
RE +E++ E + E M + E+ K R + + E +EK+ L+E
Sbjct: 538 ALSQNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVK-RELGKKLGELQEKLSELKE 596
Query: 371 MMWEKEEKIRELEEKM-----HEQEKIREQEEKRQEEEKIREQ--------EKRQEQEAK 417
+ K ++ + L+++ H Q+ + ++ E+E + Q ++ Q+QEA+
Sbjct: 597 TVELKSQEAQSLQQQRDQYLGHLQQYVAAYQQLTSEKEVLHNQLLLQTQLVDQLQQQEAQ 656
Query: 418 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
E R++ ++ +E+ + +Q +++ Q + E + + R+EE+ E+EE
Sbjct: 657 GKAVAEMARQELQETQERLEAATQQNQQLRAQLSLMAHPG--EGDGLDREEEEDEEEEE- 713
Query: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE 537
+E + + + E + +E + + EE+ R +++EQ + R
Sbjct: 714 ---EEAVAVPQPMPSIPEDLESREAMVAFFNSAVASAEEEQARLRGQLKEQRVRCRRLAH 770
Query: 538 KIR----------------------EQEEMMQEQEEKMGEQ-EEKMQEQEKMRRQEEKIR 574
+ E +Q EK+ + E MQE+ ++ + E++
Sbjct: 771 LLASAQKEPEAAAPAPGTGGDSVCGETHRALQGAMEKLQSRFMELMQEKADLKERVEELE 830
Query: 575 EQEEKIREQKEKIREQEEKIWEQ----EEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
+ ++ + + I E Q +E+ RE+EE + + E + K+ E +E
Sbjct: 831 HRCIQLSGETDTIGEYIALYQSQRAVLKERHREKEEYISRLAQDKEEMKVKLLELQE 887
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 226 bits (575), Expect = 7e-59
Identities = 166/607 (27%), Positives = 314/607 (51%), Gaps = 102/607 (16%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P+LP HPMM +E+RQ+KLA AK++L ++ + +P + A + TKKKK ++ +PETTTSG
Sbjct: 5 PYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGI-PAGAKTKKKKTDS--SPETTTSG 61
Query: 103 GCHSPEDEQ------------------------------KASHQHQEALRRELEA----- 127
GCHSP D Q + HQ +EA + E
Sbjct: 62 GCHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQM 121
Query: 128 -QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVAT 186
++ TI ILT +K +L+ LY+++ A + E E++DL RL S + ELE+AL AV+T
Sbjct: 122 ERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVST 181
Query: 187 QKKKADR-----------YIEELTKERDALSLELYRNTIT--------DE---ELKEKNA 224
Q+++ DR ++++ KER L+ + + T + DE +K + A
Sbjct: 182 QQQEEDRSSSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERA 241
Query: 225 KLQEKL--------QLVESEK------SEIQLNVKELKRKLERAKLLLPQ------QQLQ 264
+ QE++ L E +K E++ ++ ELK ++ L P +QLQ
Sbjct: 242 RWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQ 301
Query: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
EA HL +E++ + KLQ+QVE N+ + L+++Q++++ QEE ++E E + ++E++
Sbjct: 302 DEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLC 361
Query: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE 384
EQ E++REQ++ ++ Q E + ++E+++R+QEE + ++EE++++ E+ +W++EE++ + EE
Sbjct: 362 EQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEE 421
Query: 385 KMHEQEKIREQEEKRQEEEKIREQ----EKRQEQEAKMWRQEEKIREQEEKIREQE-KKM 439
++ +QE+ + + ++++ E E ++ + E++++E +EK+ E+ +
Sbjct: 422 RLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAA 481
Query: 440 WRQEEKIHEQ--------EKIREEEKRQEQEEMWRQEEKIREQEE--------IWRQKEK 483
Q +++ Q E + E+EE R I E E + KEK
Sbjct: 482 SHQNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEK 541
Query: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
E++ ++E + E E + + +E E+ IR +++ +
Sbjct: 542 ADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKV 601
Query: 544 EMMQEQE 550
++++ QE
Sbjct: 602 KLLELQE 608
Score = 140 bits (353), Expect = 4e-33
Identities = 123/487 (25%), Positives = 246/487 (50%), Gaps = 55/487 (11%)
Query: 216 DEELKEKNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
+E + K A ++KL+ + KS I K K+K + + + D +EL
Sbjct: 15 EESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGCHSPGDSQYQEL 74
Query: 275 QSVSAKLQAQVEE-NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
+ + NE L QQ+++ E +++E ++ E + E+ E I
Sbjct: 75 AVALESSSVTISQLNENIESLKQQKKQV----EHQLEEAKKTNNEIHKAQMERLETINIL 130
Query: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK-- 391
+ + ++ + R EE + +++ + + E E + + + E+++
Sbjct: 131 TLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSS 190
Query: 392 -IREQEEKRQEEEKIRE---------QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 441
RE +R ++ I+E Q ++ ++ R E + E+ R QE+ MW+
Sbjct: 191 SCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQER-MWK 249
Query: 442 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE 501
E ++EE+KR ++ R +E R E+ K +M E + V
Sbjct: 250 MSV---EARTLKEEKKR----DIHRIQELERSLSEL---KNQMAEPPSLAPPA--VTSVV 297
Query: 502 EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE-EKM 560
E++ D+ + +R++ E + E K++ Q E + +EQ++ +QEQEE + EQE +++
Sbjct: 298 EQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRV 354
Query: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
+EQE++ Q E++REQ++ ++EQ E++R+QE+++ +QEE++R++EE +Q+QE+++W+QEE
Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEE 414
Query: 621 KMCEQEEKMQEQEEKMR-RQEEKMWEQ-----------------EVRLRQQEEKMQE--H 660
++ ++EE++Q+QEE++ Q K+ +Q ++L QQ +++QE
Sbjct: 415 RLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLD 474
Query: 661 QEHLEAA 667
+EHLEAA
Sbjct: 475 EEHLEAA 481
Score = 137 bits (344), Expect = 4e-32
Identities = 119/481 (24%), Positives = 239/481 (49%), Gaps = 69/481 (14%)
Query: 186 TQKKKADRYIEELTK---------ERDALSLELYRNTITDEELKE-----KNAKLQEKLQ 231
T+KKK D E T + L++ L +++T +L E K K Q + Q
Sbjct: 46 TKKKKTDSSPETTTSGGCHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQ 105
Query: 232 LVESEKSEIQLNVKELKR-------KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
L E++K+ +++ +++R LE+A L + A H +E + ++ +LQ
Sbjct: 106 LEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYS 165
Query: 285 VE-----ENELWNRLNQQQEEKMWR--QEEKIQEWEEKIQEQEEKIREQEEKIRE--QEE 335
++ E L QQQEE +E +Q W ++ ++ + ++ E ++
Sbjct: 166 LQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQV 225
Query: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
++ R E K E+ R QE M W+ + R L+E +I+ELE + E K +
Sbjct: 226 QLERDEYAKHIKGERARWQERM-WKMSVEARTLKEEKKRDIHRIQELERSLSEL-KNQMA 283
Query: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 455
E + ++ + EAK RQE + E K+ Q E + +E
Sbjct: 284 EPPSLAPPAVTSVVEQLQDEAKHLRQE---------VEGLEGKLQSQVENNQALSLLSKE 334
Query: 456 EKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEK-IRKQEEKVWRQEEKMHDQEEKIREQ 514
QK+++ EQE+ +R+QE + R++E++ +Q E++REQ
Sbjct: 335 ------------------------QKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQ 370
Query: 515 EEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM-QEQEKMRRQEEKI 573
++ + Q E++R+QE+++R+QEE++R++EE +Q+QE+++ +QEE++ +++E++++QEE++
Sbjct: 371 QKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERL 430
Query: 574 R-EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE-EKMCEQEEKMQE 631
Q K+ +Q + + E + +++ + E+ ++E +EK+ E+ E Q ++++
Sbjct: 431 ALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLET 490
Query: 632 Q 632
Q
Sbjct: 491 Q 491
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 223 bits (567), Expect = 6e-58
Identities = 167/607 (27%), Positives = 311/607 (51%), Gaps = 102/607 (16%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P+LP HPMM +E+RQ+KLA AK++L ++ + +P + A + TKKKK ++ +PETTTSG
Sbjct: 5 PYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGI-PAGAKTKKKKTDS--SPETTTSG 61
Query: 103 GCHSPEDEQ------------------------------KASHQHQEALRRELEA----- 127
G HSP D Q + HQ +EA + E
Sbjct: 62 GGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQM 121
Query: 128 -QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVAT 186
Q+ TI ILT +K +L+ LY+++ A + E E++DL RL S + ELE+ALSAV+T
Sbjct: 122 EQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVST 181
Query: 187 QKKKADRY-----------IEELTKERDALSLELYRNTIT--------DE---ELKEKNA 224
Q+++ DR +++ KER L+ + + T + DE +K + A
Sbjct: 182 QQQEEDRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERA 241
Query: 225 KLQEKL--------QLVESEK------SEIQLNVKELKRKLERAKLLLPQ------QQLQ 264
+ QE++ L E +K E++ ++ ELK ++ L P +QLQ
Sbjct: 242 RWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQ 301
Query: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
EA HL +E++ + KLQ+QVE N+ + L+++Q++++ QEE ++E E + ++E++
Sbjct: 302 DEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLC 361
Query: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE 384
EQ E++REQ++ ++ Q E + ++E+++R+QEE + ++EE++++ E+ +W++EE++ + EE
Sbjct: 362 EQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEE 421
Query: 385 KMHEQEKIREQEEKRQEEEKIREQ----EKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
++ +QE+ + + ++++ E E ++ + E++++E +EK+ E+ +
Sbjct: 422 RLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAA 481
Query: 441 RQEEKIHEQ---------EKIREEEKRQEQEEMWRQEEKIREQEE--------IWRQKEK 483
Q + E E + E+EE R I E E + KEK
Sbjct: 482 SQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEK 541
Query: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
E++ ++E + E E + + +E E+ IR +++ +
Sbjct: 542 ADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKV 601
Query: 544 EMMQEQE 550
++++ QE
Sbjct: 602 KLLELQE 608
Score = 144 bits (363), Expect = 3e-34
Identities = 122/490 (24%), Positives = 247/490 (50%), Gaps = 61/490 (12%)
Query: 216 DEELKEKNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
+E + K A ++KL+ + KS I K K+K + + + D +EL
Sbjct: 15 EESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQYQEL 74
Query: 275 QSVSAKLQAQVEE-NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
+ + NE L QQ+++ E +++E ++ E + EQ E I
Sbjct: 75 AVALESSSVTINQLNENIESLKQQKKQV----EHQLEEAKKTNNEIHKAQMEQLETINIL 130
Query: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIR 393
+ + ++ + R EE E ++ RL+ + ++I+ELE + +
Sbjct: 131 TLEKADLKTTLYHTKRAARHFEE---ESKDLAGRLQYSL----QRIQELERAL-SAVSTQ 182
Query: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453
+QEE R + ++R +Q K + + ++ E K++ + + E K
Sbjct: 183 QQEEDRSSSCREAVLQRRLQQTIK---ERALLNAHVTQVTESLKQVQLERD---EYAKHI 236
Query: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE------------ 501
+ E+ + QE MW+ + R +E +K +H +++ + ++ Q
Sbjct: 237 KGERARWQERMWKMSVEARTLKE--EKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVT 294
Query: 502 ---EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE- 557
E++ D+ + +R++ E + E K++ Q E + +EQ++ +QEQEE + EQE
Sbjct: 295 SVVEQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEA 351
Query: 558 EKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE 617
++++EQE++ Q E++REQ++ ++EQ E++R+QE+++ +QEE++R++EE +Q+QE+++W+
Sbjct: 352 QRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWD 411
Query: 618 QEEKMCEQEEKMQEQEEKMR-RQEEKMWEQ-----------------EVRLRQQEEKMQE 659
QEE++ ++EE++Q+QEE++ Q K+ +Q ++L QQ +++QE
Sbjct: 412 QEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQE 471
Query: 660 --HQEHLEAA 667
+EHLEAA
Sbjct: 472 KLDEEHLEAA 481
Score = 132 bits (331), Expect = 1e-30
Identities = 113/456 (24%), Positives = 233/456 (51%), Gaps = 75/456 (16%)
Query: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL-QAQVEENELW 291
V E S + +N +L +E K QQ+ Q E H +E + + ++ +AQ+E+ E
Sbjct: 76 VALESSSVTIN--QLNENIESLK----QQKKQVE--HQLEEAKKTNNEIHKAQMEQLETI 127
Query: 292 NRLNQQQEE---KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
N L ++ + ++ + + +EE+ ++ +++ ++I+E E + E++
Sbjct: 128 NILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALSAVSTQQQEED 187
Query: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEK---EEKIRELEEKMHEQEKIREQEEKRQEEEKI 405
+E ++ RRL++ + E+ + ++ E + + + R++ K + E+
Sbjct: 188 RSSSCREAVL------QRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERA 241
Query: 406 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465
R QE+ MW+ + R +E EKK R +I E E+ E K Q E
Sbjct: 242 RWQER-------MWKMSVEARTLKE-----EKK--RDIHRIQELERSLSELKNQMAEPPS 287
Query: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525
+ E Q E H ++++ E K+ Q E ++Q + +E+K +++
Sbjct: 288 LAPPAVTSVVE-QLQDEAKHLRQEVEGLEGKLQSQVE--NNQALSLLSKEQK-----QRL 339
Query: 526 REQEEKIREQE-EKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIREQEEKIREQ 583
+EQEE +REQE +++REQE + EQ E++ EQ++ +QEQ E++R+QE+++R+QEE++R++
Sbjct: 340 QEQEEMLREQEAQRVREQERLC-EQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKE 398
Query: 584 KEKIREQEEKIWEQEEKIREQEEMMQEQEEKM---------------------------- 615
+E++++QE+++W+QEE++ ++EE +Q+QEE++
Sbjct: 399 EERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKS 458
Query: 616 -WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 650
+ E+++ E +EK+ E+ + Q + E ++ L
Sbjct: 459 ALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSL 494
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 221 bits (564), Expect = 1e-57
Identities = 166/607 (27%), Positives = 310/607 (51%), Gaps = 102/607 (16%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P+LP HPMM +E+RQ+KLA AK++L ++ + +P + A + TKKKK ++ +PETTTSG
Sbjct: 5 PYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGI-PAGAKTKKKKTDS--SPETTTSG 61
Query: 103 GCHSPEDEQ------------------------------KASHQHQEALRRELEA----- 127
G HSP D Q + HQ +EA + E
Sbjct: 62 GGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQM 121
Query: 128 -QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVAT 186
Q+ TI ILT +K +L+ LY+++ A + E E++DL RL S + ELE+AL AV+T
Sbjct: 122 EQLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVST 181
Query: 187 QKKKADRY-----------IEELTKERDALSLELYRNTIT--------DE---ELKEKNA 224
Q+++ DR +++ KER L+ + + T + DE +K + A
Sbjct: 182 QQQEEDRSSSCREAVLQRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERA 241
Query: 225 KLQEKL--------QLVESEK------SEIQLNVKELKRKLERAKLLLPQ------QQLQ 264
+ QE++ L E +K E++ ++ ELK ++ L P +QLQ
Sbjct: 242 RWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQ 301
Query: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
EA HL +E++ + KLQ+QVE N+ + L+++Q++++ QEE ++E E + ++E++
Sbjct: 302 DEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLC 361
Query: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE 384
EQ E++REQ++ ++ Q E + ++E+++R+QEE + ++EE++++ E+ +W++EE++ + EE
Sbjct: 362 EQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEE 421
Query: 385 KMHEQEKIREQEEKRQEEEKIREQ----EKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
++ +QE+ + + ++++ E E ++ + E++++E +EK+ E+ +
Sbjct: 422 RLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAA 481
Query: 441 RQEEKIHEQ---------EKIREEEKRQEQEEMWRQEEKIREQEE--------IWRQKEK 483
Q + E E + E+EE R I E E + KEK
Sbjct: 482 SQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEK 541
Query: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
E++ ++E + E E + + +E E+ IR +++ +
Sbjct: 542 ADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKV 601
Query: 544 EMMQEQE 550
++++ QE
Sbjct: 602 KLLELQE 608
Score = 142 bits (357), Expect = 1e-33
Identities = 122/490 (24%), Positives = 246/490 (50%), Gaps = 61/490 (12%)
Query: 216 DEELKEKNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
+E + K A ++KL+ + KS I K K+K + + + D +EL
Sbjct: 15 EESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQYQEL 74
Query: 275 QSVSAKLQAQVEE-NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
+ + NE L QQ+++ E +++E ++ E + EQ E I
Sbjct: 75 AVALESSSVTINQLNENIESLKQQKKQV----EHQLEEAKKTNNEIHKAQMEQLETINIL 130
Query: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIR 393
+ + ++ + R EE E ++ RL+ + + I+ELE + +
Sbjct: 131 TLEKADLKTTLYHTKRAARHFEE---ESKDLAGRLQYSL----QHIQELERALCAVST-Q 182
Query: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453
+QEE R + ++R +Q K + + ++ E K++ + + E K
Sbjct: 183 QQEEDRSSSCREAVLQRRLQQTIK---ERALLNAHVTQVTESLKQVQLERD---EYAKHI 236
Query: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE------------ 501
+ E+ + QE MW+ + R +E +K +H +++ + ++ Q
Sbjct: 237 KGERARWQERMWKMSVEARTLKE--EKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVT 294
Query: 502 ---EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE- 557
E++ D+ + +R++ E + E K++ Q E + +EQ++ +QEQEE + EQE
Sbjct: 295 SVVEQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEA 351
Query: 558 EKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE 617
++++EQE++ Q E++REQ++ ++EQ E++R+QE+++ +QEE++R++EE +Q+QE+++W+
Sbjct: 352 QRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWD 411
Query: 618 QEEKMCEQEEKMQEQEEKMR-RQEEKMWEQ-----------------EVRLRQQEEKMQE 659
QEE++ ++EE++Q+QEE++ Q K+ +Q ++L QQ +++QE
Sbjct: 412 QEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQE 471
Query: 660 --HQEHLEAA 667
+EHLEAA
Sbjct: 472 KLDEEHLEAA 481
Score = 130 bits (326), Expect = 5e-30
Identities = 113/456 (24%), Positives = 232/456 (50%), Gaps = 75/456 (16%)
Query: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL-QAQVEENELW 291
V E S + +N +L +E K QQ+ Q E H +E + + ++ +AQ+E+ E
Sbjct: 76 VALESSSVTIN--QLNENIESLK----QQKKQVE--HQLEEAKKTNNEIHKAQMEQLETI 127
Query: 292 NRLNQQQEE---KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
N L ++ + ++ + + +EE+ ++ +++ + I+E E + E++
Sbjct: 128 NILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQHIQELERALCAVSTQQQEED 187
Query: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEK---EEKIRELEEKMHEQEKIREQEEKRQEEEKI 405
+E ++ RRL++ + E+ + ++ E + + + R++ K + E+
Sbjct: 188 RSSSCREAVL------QRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERA 241
Query: 406 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465
R QE+ MW+ + R +E EKK R +I E E+ E K Q E
Sbjct: 242 RWQER-------MWKMSVEARTLKE-----EKK--RDIHRIQELERSLSELKNQMAEPPS 287
Query: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525
+ E Q E H ++++ E K+ Q E ++Q + +E+K +++
Sbjct: 288 LAPPAVTSVVE-QLQDEAKHLRQEVEGLEGKLQSQVE--NNQALSLLSKEQK-----QRL 339
Query: 526 REQEEKIREQE-EKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIREQEEKIREQ 583
+EQEE +REQE +++REQE + EQ E++ EQ++ +QEQ E++R+QE+++R+QEE++R++
Sbjct: 340 QEQEEMLREQEAQRVREQERLC-EQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKE 398
Query: 584 KEKIREQEEKIWEQEEKIREQEEMMQEQEEKM---------------------------- 615
+E++++QE+++W+QEE++ ++EE +Q+QEE++
Sbjct: 399 EERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKS 458
Query: 616 -WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 650
+ E+++ E +EK+ E+ + Q + E ++ L
Sbjct: 459 ALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSL 494
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 220 bits (561), Expect = 3e-57
Identities = 165/607 (27%), Positives = 312/607 (51%), Gaps = 102/607 (16%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P+LP HPMM +E+RQ+KLA AK++L ++ + +P + A + TKKKK ++ +PETTTSG
Sbjct: 5 PYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGI-PAGAKTKKKKTDS--SPETTTSG 61
Query: 103 GCHSPEDEQ------------------------------KASHQHQEALRRELEA----- 127
G HSP D Q + HQ +EA + E
Sbjct: 62 GGHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQM 121
Query: 128 -QVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVAT 186
++ TI ILT +K +L+ LY+++ A + E E++DL RL S + ELE+AL AV+T
Sbjct: 122 ERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVST 181
Query: 187 QKKKADRY-----------IEELTKERDALSLELYRNTIT--------DE---ELKEKNA 224
Q+++ DR +++ KER L+ + + T + DE +K + A
Sbjct: 182 QQQEEDRSSSCREAVLHRRLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERA 241
Query: 225 KLQEKL--------QLVESEK------SEIQLNVKELKRKLERAKLLLPQ------QQLQ 264
+ QE++ L E +K E++ ++ ELK ++ + L P +QLQ
Sbjct: 242 RWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQ 301
Query: 265 AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
EA HL +E++ + KLQ+QVE N+ + L+++Q++++ QEE ++E E + ++E++
Sbjct: 302 DEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLC 361
Query: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE 384
EQ E++REQ++ ++ Q E + ++E+++R+QEE + ++EE++++ E+ +W++EE++ + EE
Sbjct: 362 EQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEE 421
Query: 385 KMHEQEKIREQEEKRQEEEKIREQ----EKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
++ +QE+ + + ++++ E E ++ + E++++E +EK+ E+ +
Sbjct: 422 RLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAA 481
Query: 441 RQEEKIHEQ---------EKIREEEKRQEQEEMWRQEEKIREQEE--------IWRQKEK 483
Q+ + E E + E+EE R I E E + KEK
Sbjct: 482 SQQNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEK 541
Query: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
E++ ++E + E E + + +E E+ IR +++ +
Sbjct: 542 ADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKV 601
Query: 544 EMMQEQE 550
++++ QE
Sbjct: 602 KLLELQE 608
Score = 141 bits (355), Expect = 2e-33
Identities = 123/488 (25%), Positives = 246/488 (50%), Gaps = 57/488 (11%)
Query: 216 DEELKEKNAKLQEKLQLVESEKSE-IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL 274
+E + K A ++KL+ + KS I K K+K + + + D +EL
Sbjct: 15 EESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGGHSPGDSQYQEL 74
Query: 275 QSVSAKLQAQVEE-NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
+ + NE L QQ+++ E +++E ++ E + E+ E I
Sbjct: 75 AVALESSSVTISQLNENIESLKQQKKQV----EHQLEEAKKTNNEIHKAQMERLETINIL 130
Query: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIR 393
+ + ++ + R EE E ++ RL+ + ++I+ELE + +
Sbjct: 131 TLEKADLKTTLYHTKRAARHFEE---ESKDLAGRLQYSL----QRIQELERALCAVST-Q 182
Query: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453
+QEE R + +R +Q K + + ++ E K++ + + E K
Sbjct: 183 QQEEDRSSSCREAVLHRRLQQTIK---ERALLNAHVTQVTESLKQVQLERD---EYAKHI 236
Query: 454 EEEKRQEQEEMWRQEEKIR-----EQEEIWRQKEKMHEQEKIRKQEEK--------VWRQ 500
+ E+ + QE MW+ + R ++ +I R +E +++ Q K V
Sbjct: 237 KGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSV 296
Query: 501 EEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE-EK 559
E++ D+ + +R++ E + E K++ Q E + +EQ++ +QEQEE + EQE ++
Sbjct: 297 VEQLQDEAKHLRQEVEGL---EGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQR 353
Query: 560 MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619
++EQE++ Q E++REQ++ ++EQ E++R+QE+++ +QEE++R++EE +Q+QE+++W+QE
Sbjct: 354 VREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE 413
Query: 620 EKMCEQEEKMQEQEEKMR-RQEEKMWEQ-----------------EVRLRQQEEKMQE-- 659
E++ ++EE++Q+QEE++ Q K+ +Q ++L QQ +++QE
Sbjct: 414 ERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKL 473
Query: 660 HQEHLEAA 667
+EHLEAA
Sbjct: 474 DEEHLEAA 481
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 216 bits (549), Expect = 7e-56
Identities = 112/177 (63%), Positives = 145/177 (81%), Gaps = 6/177 (3%)
Query: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE 551
++EE++ +E+KM ++EE +REQEEKM QEEK+REQEEK+ EQEEK++EQEE M EQEE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 552 KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE----QEEM 607
KM EQEEKM EQ+++ Q+EK+ EQ+E++RE++E++REQ K+W+Q EK+RE QEE
Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEKMREKKKTQEEK 119
Query: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
MQEQEEKM EQEE M EQEEKMQEQEEKM QEEKM EQE ++R+QEEKMQ +E +
Sbjct: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Score = 214 bits (545), Expect = 2e-55
Identities = 109/178 (61%), Positives = 145/178 (81%), Gaps = 2/178 (1%)
Query: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
M E+E++R++E+K+ +EE M +QEEK++EQEEKM QEEK+ EQEEK++EQEEK+ EQE
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK--EKIREQEEKIWEQEEKI 601
E M EQEEKM EQ+ +++EKM Q+E++RE+EE++REQK +++ + EK QEEK+
Sbjct: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
Query: 602 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
+EQEE MQEQEE MWEQEEKM EQEEKM EQEEKMR QEEKM EQE +++ QEEKM++
Sbjct: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRD 178
Score = 212 bits (540), Expect = 8e-55
Identities = 117/191 (61%), Positives = 153/191 (80%), Gaps = 14/191 (7%)
Query: 459 QEQEEMWRQEEKIREQEEIWR-QKEKMHEQE-KIRKQEEKVWRQEEKMHDQEEKIREQEE 516
+E+E M +E+K+RE+EE+ R Q+EKM EQE K+R+QEEK+W QEEKM +QEEK+ EQEE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 517 KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
KMW QEEK+ EQ+ ++ EQ+EK+ EQ+E ++E+EE+M EQ+ Q+ EKMR EK + Q
Sbjct: 62 KMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK-MWQQVEKMR---EKKKTQ 116
Query: 577 EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636
EEK++EQ+EK++EQEE +WEQEEK MQEQEEKMWEQEEKM EQEEKM+EQEEKM
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEK-------MQEQEEKMWEQEEKMREQEEKMREQEEKM 169
Query: 637 RRQEEKMWEQE 647
+ QEEKM + E
Sbjct: 170 QGQEEKMRDVE 180
Score = 209 bits (532), Expect = 7e-54
Identities = 110/191 (57%), Positives = 149/191 (78%), Gaps = 14/191 (7%)
Query: 375 KEEKIRELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
+EE++RE E+KM E+E++ REQEEK QE+E EK +EQE KMW QEEK++EQEEK+
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQE-----EKMREQEEKMWEQEEKMQEQEEKMW 57
Query: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
EQE+KMW QEEK+ EQ+++ E++ E+MW Q+E++RE+EE R+++ + EK+R
Sbjct: 58 EQEEKMWEQEEKMWEQQRLPEQK-----EKMWEQDERLREKEERMREQKMWQQVEKMR-- 110
Query: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
EK QEEKM +QEEK++EQEE MW QEEK++EQEEK+ EQEEK+REQEE M+EQEEKM
Sbjct: 111 -EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 169
Query: 554 GEQEEKMQEQE 564
QEEKM++ E
Sbjct: 170 QGQEEKMRDVE 180
Score = 205 bits (521), Expect = 1e-52
Identities = 119/219 (54%), Positives = 158/219 (72%), Gaps = 29/219 (13%)
Query: 400 QEEEKIREQEKRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EEK 457
+EEE++RE+EK+ +E +M R QEEK++EQEEK+REQE+KMW E EEK
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW-------------EQEEK 48
Query: 458 RQEQEE-MWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516
QEQEE MW QEEK +W Q+EKM EQ+++ +Q+EK+W Q+E++ ++EE++REQ
Sbjct: 49 MQEQEEKMWEQEEK------MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ-- 100
Query: 517 KMWRQEEKIRE----QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEE 571
KMW+Q EK+RE QEEK++EQEEK++EQEEMM EQEEKM EQEEKM EQ EKMR QEE
Sbjct: 101 KMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160
Query: 572 KIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQE 610
K+REQEEK++ Q+EK+R+ E E E + QE
Sbjct: 161 KMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
Score = 200 bits (509), Expect = 3e-51
Identities = 109/206 (52%), Positives = 149/206 (72%), Gaps = 19/206 (9%)
Query: 353 RQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 412
R+EE M E+E+KMR EEMM E+EEK++E EEKM REQEEK E+E EK Q
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKM------REQEEKMWEQE-----EKMQ 50
Query: 413 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 472
EQE KMW QEEK+ EQEEK+ EQ++ ++E+ + E++RE+E+R +++MW+Q EK+R
Sbjct: 51 EQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMR 110
Query: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI 532
E +K ++EK+++QEEK+ QEE M +QEEK++EQEEKMW QEEK+REQEEK+
Sbjct: 111 E--------KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 162
Query: 533 REQEEKIREQEEMMQEQEEKMGEQEE 558
REQEEK++ QEE M++ E GE E
Sbjct: 163 REQEEKMQGQEEKMRDVEPAGGEAGE 188
Score = 199 bits (505), Expect = 9e-51
Identities = 116/225 (51%), Positives = 155/225 (68%), Gaps = 30/225 (13%)
Query: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEK 385
+EE++RE+E+KMR +EEMM E+EEKM+ E+EEKMR EE MWE+EEK++E EEK
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQ-------EQEEKMREQEEKMWEQEEKMQEQEEK 55
Query: 386 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 445
M EQE E+ ++EEK+ EQ++ EQ+ KMW Q+E++RE+EE++REQ KMW+Q EK
Sbjct: 56 MWEQE-----EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQ--KMWQQVEK 108
Query: 446 IHEQEKIREEEKRQEQEE-MWRQEEKIREQEE-IWRQKEKMHEQEKIRKQEEKVWRQEEK 503
+ E K++ QEE M QEEK++EQEE +W Q+EKM E QEEK+W QEEK
Sbjct: 109 MRE--------KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQE------QEEKMWEQEEK 154
Query: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQE 548
M +QEEK+REQEEKM QEEK+R+ E E E + QE
Sbjct: 155 MREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
Score = 197 bits (502), Expect = 2e-50
Identities = 107/202 (52%), Positives = 152/202 (75%), Gaps = 25/202 (12%)
Query: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
R+EE++RE+E+K+RE+E+ M QEEK+ EQE E+ R+++E+MW QEEK++EQEE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQE----EKMREQEEKMWEQEEKMQEQEE--- 54
Query: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE--E 537
K+ +QEEK+W QEEKM +Q+ ++ EQ+EKMW Q+E++RE+EE++REQ+ +
Sbjct: 55 ---------KMWEQEEKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQKMWQ 104
Query: 538 KIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQ 597
++ + E + QEEKM EQEEKMQEQE+M + EQEEK++EQ+EK+ EQEEK+ EQ
Sbjct: 105 QVEKMREKKKTQEEKMQEQEEKMQEQEEM------MWEQEEKMQEQEEKMWEQEEKMREQ 158
Query: 598 EEKIREQEEMMQEQEEKMWEQE 619
EEK+REQEE MQ QEEKM + E
Sbjct: 159 EEKMREQEEKMQGQEEKMRDVE 180
Score = 197 bits (502), Expect = 2e-50
Identities = 111/196 (56%), Positives = 145/196 (73%), Gaps = 24/196 (12%)
Query: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378
+EE++RE+E+K+RE+EE MR QEE M E+EEKMR QEE MWE+EEKM+ EE MWE+EEK
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 379 IRELEEKMHEQEKIREQEEKR-QEEEKIREQEKRQEQEAKMWRQEEKIRE----QEEKIR 433
+ E EEKM EQ+++ EQ+EK +++E++RE+E+R +E KMW+Q EK+RE QEEK++
Sbjct: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERM-REQKMWQQVEKMREKKKTQEEKMQ 121
Query: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEE-MWRQEEKIREQEEIWRQKEKMHEQEKIRK 492
EQE+KM QEE + EQE EK QEQEE MW QEEK+REQE EK+R+
Sbjct: 122 EQEEKMQEQEEMMWEQE-----EKMQEQEEKMWEQEEKMREQE------------EKMRE 164
Query: 493 QEEKVWRQEEKMHDQE 508
QEEK+ QEEKM D E
Sbjct: 165 QEEKMQGQEEKMRDVE 180
Score = 193 bits (491), Expect = 4e-49
Identities = 104/199 (52%), Positives = 147/199 (73%), Gaps = 7/199 (3%)
Query: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
+++E+KM +EE ++E EEK+QEQEEK+REQEEK+ EQEEKM+ QEE MWE+EEKM QE
Sbjct: 8 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 67
Query: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415
E MWE ++++ +E MWE++E++RE EE+M EQ K+ +Q EK +E++K +E EK QEQE
Sbjct: 68 EKMWE-QQRLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKKTQE-EKMQEQE 124
Query: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475
KM QEE + EQEEK++EQE+KMW QEEK+ EQ EE+ R+++E+M QEEK+R+ E
Sbjct: 125 EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQ----EEKMREQEEKMQGQEEKMRDVE 180
Query: 476 EIWRQKEKMHEQEKIRKQE 494
+ + Q+ QE
Sbjct: 181 PAGGEAGEGSPQDNPTAQE 199
Score = 191 bits (486), Expect = 1e-48
Identities = 102/169 (60%), Positives = 132/169 (78%), Gaps = 18/169 (10%)
Query: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE-KMRRQEEK 572
+EE+M +E+K+RE+EE +REQEEK++EQEE M+EQEEKM EQEEKMQEQE KM QEEK
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 573 IREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQE----------------QEEKMW 616
+ EQEEK+ EQ +++ EQ+EK+WEQ+E++RE+EE M+E QEEKM
Sbjct: 63 MWEQEEKMWEQ-QRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
Query: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
EQEEKM EQEE M EQEEKM+ QEEKMWEQE ++R+QEEKM+E +E ++
Sbjct: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 170
Score = 138 bits (348), Expect = 1e-32
Identities = 82/185 (44%), Positives = 120/185 (64%), Gaps = 30/185 (16%)
Query: 244 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN--QQQEEK 301
++E +R ER K + ++++ E + +++Q K++ Q E ++W + Q+QEEK
Sbjct: 1 MREEERMREREKKMREEEEMMREQE---EKMQEQEEKMREQ--EEKMWEQEEKMQEQEEK 55
Query: 302 MWRQEEKIQE-----WE--------EKIQEQEEKIREQEEKIREQE---------EKMRR 339
MW QEEK+ E WE EK+ EQ+E++RE+EE++REQ+ EK +
Sbjct: 56 MWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT 115
Query: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ-EKIREQEEK 398
QEE M E+EEKM+ QEEMMWE+EEKM+ EE MWE+EEK+RE EEKM EQ EK++ QEEK
Sbjct: 116 QEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 175
Query: 399 RQEEE 403
++ E
Sbjct: 176 MRDVE 180
Score = 134 bits (337), Expect = 3e-31
Identities = 74/206 (35%), Positives = 131/206 (63%), Gaps = 16/206 (7%)
Query: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
+E ++E+ K++E+ +++ ++ ++Q +E K + + K+ ++++Q + + + ++ +
Sbjct: 4 EERMREREKKMREEEEMMREQEEKMQ--EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE-----EKIRE----Q 326
+ + + E+ L +Q+EKMW Q+E+++E EE+++EQ+ EK+RE Q
Sbjct: 62 KMWEQEEKMWEQQRL-----PEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116
Query: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM 386
EEK++EQEEKM+ QEEMMWE+EEKM+ QEE MWE+EEKMR EE M E+EEK++ EEKM
Sbjct: 117 EEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Query: 387 HEQEKIREQEEKRQEEEKIREQEKRQ 412
+ E + + ++ QE Q
Sbjct: 177 RDVEPAGGEAGEGSPQDNPTAQEIMQ 202
Score = 85.9 bits (211), Expect = 1e-16
Identities = 42/64 (65%), Positives = 54/64 (84%), Gaps = 1/64 (1%)
Query: 601 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660
+RE+E M+E+E+KM E+EE M EQEEKMQEQEEKMR QEEKMWEQE ++++QEEKM E
Sbjct: 1 MREEER-MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 661 QEHL 664
+E +
Sbjct: 60 EEKM 63
Score = 81.6 bits (200), Expect = 2e-15
Identities = 55/153 (35%), Positives = 80/153 (52%), Gaps = 32/153 (20%)
Query: 196 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 255
EE E++ E R E++ E++ +L+EK + + +K Q+ K+K + K
Sbjct: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
Query: 256 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 315
+ Q +E ++ Q+QEE MW QEEK+QE EEK
Sbjct: 120 M---------------------------QEQEEKM-----QEQEEMMWEQEEKMQEQEEK 147
Query: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
+ EQEEK+REQEEK+REQEEKM+ QEE M + E
Sbjct: 148 MWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 213 bits (543), Expect = 4e-55
Identities = 153/503 (30%), Positives = 255/503 (50%), Gaps = 115/503 (22%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP HP MS++T+Q KLA AK++L + + +P + A+ +KKK+N G++P+T TSG
Sbjct: 5 PRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGAN--RKKKVN-GSSPDTATSG 61
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
G HSP D + GE R
Sbjct: 62 GYHSPGDSATGIY------------------------------------------GEGRA 79
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
+ L D LE +A + I +LT+ ++L T +E K+
Sbjct: 80 SSTTLQD-------LESQYQELAVALDSSSAIISQLTENINSL-------VRTSKEEKKH 125
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--------QQLQAEADHLGKEL 274
L +KL K K + A+ L P+ +QLQ E +HL KEL
Sbjct: 126 EIHLVQKL------------GRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKEL 173
Query: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
+SV +LQA+VE N++ + LN++QEE++ QEE++ E EE++ EQEE++ EQEE++ EQE
Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQE 233
Query: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE 394
E++R QEE + E+EE++ Q EE + E+EE++ E EE++ EQEK+
Sbjct: 234 ERLREQEERLREQEERLHEQ--------------EERLCEQEERLCEQEERLCEQEKLPG 279
Query: 395 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 454
QE +E EK+ EQE+RQE++ ++ +E + E EE + EQE++R+
Sbjct: 280 QERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELL---------------EQERLRQ 324
Query: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQ 514
+++R Q+E R+ E++RE E++ E E++R+ E + E +++Q + R
Sbjct: 325 QDERLWQQETLRELERLRE-------LERLRELERLRELERMLELGWEALYEQRAEPRSG 377
Query: 515 EEKMWRQEEKIREQEEKIREQEE 537
E++ + + + E++++E E+
Sbjct: 378 FEELNNENKSTLQLEQQVKELEK 400
Score = 147 bits (370), Expect = 4e-35
Identities = 85/230 (36%), Positives = 150/230 (65%), Gaps = 20/230 (8%)
Query: 450 EKIREEEK--RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
E++++E R+E E + RQ + E ++ + E E++R+QEE++ QEE++H+Q
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQE-ERLREQEERLHEQEERLHEQ 218
Query: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
EE++ EQEE++ QEE++REQEE++REQEE++ EQEE + EQEE++ EQEE++ EQEK+
Sbjct: 219 EERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLP 278
Query: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ-----EQEEKMWEQE--- 619
Q E++ E+ EK+ EQ E+ +E++E++ E+E + E EE+++ +Q+E++W+QE
Sbjct: 279 GQ-ERLLEEVEKLLEQ-ERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLR 336
Query: 620 --EKMCEQE-----EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
E++ E E E+++E E + E ++EQ R E++ +
Sbjct: 337 ELERLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENK 386
Score = 142 bits (357), Expect = 1e-33
Identities = 96/330 (29%), Positives = 187/330 (56%), Gaps = 32/330 (9%)
Query: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE--EKI-REQ 408
R + + E + + L + I +L E ++ + ++E+K + +K+ R
Sbjct: 78 RASSTTLQDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSL 137
Query: 409 EKRQEQEAKMWRQE--------EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 460
K + Q A+ E E+++++ +R++ + + RQ + E ++ R++
Sbjct: 138 FKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQ 197
Query: 461 QEEMWRQEEKIREQEEIWRQKEKMHEQ-EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMW 519
+E + QEE++ EQE E++HEQ E++ +QEE++ QEE++ +QEE++REQEE++
Sbjct: 198 EERLREQEERLHEQE------ERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLH 251
Query: 520 RQEEKIREQEEKIREQEEKIREQE-----EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIR 574
QEE++ EQEE++ EQEE++ EQE E + E+ EK+ EQE + +EQE++ +E +
Sbjct: 252 EQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLD 311
Query: 575 EQEEKIREQKEKIREQEEKIWEQE-----EKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 629
E EE + ++E++R+Q+E++W+QE E++RE E + + E++ E E + E +
Sbjct: 312 EVEELL--EQERLRQQDERLWQQETLRELERLRELERL--RELERLRELERMLELGWEAL 367
Query: 630 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
EQ + R E++ + Q E++++E
Sbjct: 368 YEQRAEPRSGFEELNNENKSTLQLEQQVKE 397
Score = 137 bits (345), Expect = 3e-32
Identities = 81/201 (40%), Positives = 133/201 (66%), Gaps = 25/201 (12%)
Query: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
E +RK+ E V RQ + + + + RQEE++REQEE++ EQEE++ EQEE
Sbjct: 165 ETNHLRKELESVGRQLQAEVENNQMLSLLNR---RQEERLREQEERLHEQEERLHEQEER 221
Query: 546 MQEQEEKMGEQEEKMQEQE-KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE-----E 599
+ EQEE++ EQEE+++EQE ++R QEE++ EQEE++ EQ+E++ EQEE++ EQE E
Sbjct: 222 LCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQE 281
Query: 600 KIREQEEMMQEQEEKMWEQE-----EKMCEQEEKMQEQEEKMRRQEEKMWEQEV-----R 649
++ E+ E + EQE + EQE E++ ++ E++ EQE ++R+Q+E++W+QE R
Sbjct: 282 RLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQE-RLRQQDERLWQQETLRELER 340
Query: 650 LRQQE-----EKMQEHQEHLE 665
LR+ E E+++E + LE
Sbjct: 341 LRELERLRELERLRELERMLE 361
Score = 135 bits (341), Expect = 9e-32
Identities = 97/341 (28%), Positives = 191/341 (56%), Gaps = 25/341 (7%)
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Q L+++ L L S SA + E R ++++++ +K+ K++ Q
Sbjct: 85 QDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQT 144
Query: 321 -EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379
E + + + E+++ + + ++ E + RQ + E + + L +EE++
Sbjct: 145 AEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR---RQEERL 201
Query: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ-EQEAKMWRQEEKIREQEEKIREQEKK 438
RE EE++HEQE E ++EE++ EQE+R EQE ++ QEE++REQEE++ EQE++
Sbjct: 202 REQEERLHEQE-----ERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEER 256
Query: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498
+ QEE++ EQ EE+ EQE++ QE + E E++ Q+ + EQE++ ++E +
Sbjct: 257 LCEQEERLCEQ-----EERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLD 311
Query: 499 RQEEKMHDQEEKIREQEEKMWRQE-----EKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
EE + ++E++R+Q+E++W+QE E++RE E++RE E++RE E M++ E +
Sbjct: 312 EVEELL--EQERLRQQDERLWQQETLRELERLREL-ERLREL-ERLRELERMLELGWEAL 367
Query: 554 GEQE-EKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEK 593
EQ E E++ + + + E++++E ++ +E +
Sbjct: 368 YEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 408
Score = 126 bits (316), Expect = 7e-29
Identities = 85/288 (29%), Positives = 162/288 (56%), Gaps = 35/288 (12%)
Query: 383 EEKMHEQEKIREQEE-----KRQEEEKIREQEKRQEQEAKMWRQEEK-IREQEEKIREQE 436
EEK HE +++ K Q E + + + + + E +R++ E + Q
Sbjct: 121 EEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQL 180
Query: 437 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE-IWRQKEKMHEQE-KIRKQE 494
+ + + + +EE R+++E + QEE++ EQEE + Q+E++ EQE ++R+QE
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQE 240
Query: 495 EKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQE-----EKIREQEEKIREQEEMMQEQ 549
E++ QEE++H+QEE++ EQEE++ QEE++ EQE E++ E+ EK+ EQE +EQ
Sbjct: 241 ERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQ 300
Query: 550 E-----EKMGEQEEKMQEQEKMRRQEEKIREQE-----EKIRE-----QKEKIREQE--- 591
E E++ ++ E++ EQE++R+Q+E++ +QE E++RE + E++RE E
Sbjct: 301 ERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELERLRELERLRELERLRELERML 360
Query: 592 ----EKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 635
E ++EQ + R E + + + + E+++ E E+ +E +
Sbjct: 361 ELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 408
Score = 105 bits (262), Expect = 1e-22
Identities = 59/152 (38%), Positives = 94/152 (61%), Gaps = 8/152 (5%)
Query: 521 QEEKIREQE--EKIREQEEKIREQ--EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
+EEK E +K+ K++ Q E + E + E+ E +R++ E + Q
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 577 EEKIREQKEKI----REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632
+ E + + R QEE++ EQEE++ EQEE + EQEE++ EQEE++CEQEE+++EQ
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQ 239
Query: 633 EEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
EE++R QEE++ EQE RL +QEE++ E +E L
Sbjct: 240 EERLREQEERLHEQEERLCEQEERLCEQEERL 271
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 183 bits (464), Expect = 5e-46
Identities = 110/449 (24%), Positives = 259/449 (57%), Gaps = 20/449 (4%)
Query: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
E+L + LQE +L E ++ N+ K K ++ K + L+ E G+E +
Sbjct: 1501 EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDE-EEVTLEEEVSREGEEKEQ 1559
Query: 277 VSAKLQAQVEENELWNRLNQQQ---EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
+ Q ++E W R+++++ E+K ++E K+ + EEK+ ++E ++ ++E K+ +
Sbjct: 1560 QVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQA 1619
Query: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM-HEQEKI 392
K+ + + M + E K ++EE + ++ EK+ + E + +K +K+ + EK+ E+EK+
Sbjct: 1620 YVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKL 1679
Query: 393 REQEEKRQEEEKIREQ---EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 449
++ K E + I Q E Q ++ W+++E +E EE + E+ W++EE E+
Sbjct: 1680 AKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEE 1739
Query: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQE-KIRKQEEKVWRQEEKMHDQE 508
K+ EE+K+ +EE E + Q+EK+ E+E K+ ++EE + +++EK+ +
Sbjct: 1740 GKLVEEKKKLAEEE-----------EALAWQREKLSEEETKLAQEEELLIQEKEKLAQHK 1788
Query: 509 EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRR 568
EK+ E+EE++ R+ E++ E++ K+ ++ E+ E + + + + +++ QE++ + +
Sbjct: 1789 EKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQ 1848
Query: 569 QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628
++EK+ +++E + KE++ ++++ + + K+ +++ + EEK+ +++E + +++EK
Sbjct: 1849 EKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEK 1908
Query: 629 MQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657
+ E E+K+ + E+ + +++ +L Q++ K+
Sbjct: 1909 LAETEKKLVQVEDSLAKKQEKLAQEKMKL 1937
Score = 178 bits (452), Expect = 1e-44
Identities = 129/550 (23%), Positives = 295/550 (53%), Gaps = 55/550 (10%)
Query: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223
IS+ + F +Q AV +++K + E+TKE +S E+ L+EK
Sbjct: 1387 ISKKEEKKTFQKSPKQGRKAVQ-KERKVGKIKREMTKEERDMSEEVEEMAT----LEEKV 1441
Query: 224 AKLQEKLQLVESEKS----------------EIQLNVKELKRKLERAKLLLPQQQLQAEA 267
K + KL ++E S E + + K K + E+ +LL +++L
Sbjct: 1442 VKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEK-RLLQEEEKLHQAG 1500
Query: 268 DHLGKELQSVSAKLQAQVEE-NELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
+ L E + + + + EE ++W N L+ + +E+ ++ EE++ EE +E EEK ++
Sbjct: 1501 EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQ 1560
Query: 326 QEEKIR--EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE 383
E+ R ++E K R E+K ++E + ++EEK+ + E + ++E K+ +
Sbjct: 1561 VTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAY 1620
Query: 384 EKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEA-KMWRQEEKIREQEEKIREQEKKMW 440
K+ + ++ Q E + Q+EE + ++ ++ QEA K+ ++ +K+ ++ EK+ +E+K+
Sbjct: 1621 VKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLA 1680
Query: 441 RQEEKIHEQEKI-----------------REEEKRQEQEEM--------WRQEEKIREQE 475
++ K+ E + I +E+E QE EE+ W++EE +E+
Sbjct: 1681 KKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEG 1740
Query: 476 EIWRQKEKMHEQEK-IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE 534
++ +K+K+ E+E+ + Q EK+ +E K+ +EE + +++EK+ + +EK+ E+EE++
Sbjct: 1741 KLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGR 1800
Query: 535 QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI 594
+ E++ E++ + ++ E+ E++ + + + Q++ + ++++ + ++KEK+ +++E +
Sbjct: 1801 KREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENL 1860
Query: 595 WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654
+E++ ++ + + + K+ + + + EEK+ +++E + +++EK+ E E +L Q E
Sbjct: 1861 LYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVE 1920
Query: 655 EKMQEHQEHL 664
+ + + QE L
Sbjct: 1921 DSLAKKQEKL 1930
Score = 174 bits (441), Expect = 2e-43
Identities = 127/500 (25%), Positives = 273/500 (54%), Gaps = 46/500 (9%)
Query: 187 QKKKADRY-IEE----LTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 241
QKK D +EE L K + + LE T+ E K++ K +K + + +
Sbjct: 1351 QKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKE 1410
Query: 242 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE- 300
V ++KR++ + + + ++ E L +++ KL +E W + +E
Sbjct: 1411 RKVGKIKREMTKEERDMSEEV--EEMATLEEKVVKQEGKL-VMIERTPSWQDWKKAWDEW 1467
Query: 301 --------KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
K W+ + +EWE+++ ++EEK+ + EK+ +EE ++ +++ WE+ +++
Sbjct: 1468 KQVHGETRKSWKAWK--EEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVW 1525
Query: 353 RQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 412
KE++ + EE+ E EE RE EEK EQ+ EQ ++E + R KR
Sbjct: 1526 ENMLSSKSKEQQYKDEEEVTLE-EEVSREGEEK--EQQVTEEQRHIQEEHKWARIHRKRA 1582
Query: 413 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEKI 471
E K ++E K+ ++EEK+ ++E+++ ++E K+ + KI ++++ EM + E K
Sbjct: 1583 RAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDR-----EMAQAEGKF 1637
Query: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK 531
++EE Q+ EK+ ++ EK+ ++ +K+ + EK+ +EEK+ ++ K+ E +
Sbjct: 1638 AQKEETLAQRG-----EKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNI 1692
Query: 532 IREQEEKIREQEEMMQEQEEKMGEQEEKMQ-EQEKMRRQEEKIREQEEKIREQKEKIREQ 590
+ ++ E++ ++E+ + QE+++ ++ E+++ + E++ +EE++ ++E K+ E+K+K+ E+
Sbjct: 1693 LAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEE 1752
Query: 591 EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ------EQEEKMRRQEEKMW 644
EE + Q EK+ E+E + ++EE + +++EK+ Q E+EE++ R+ E++
Sbjct: 1753 EEALAWQREKLSEEETKLAQEEELLIQEKEKLA------QHKEKMPEEEERLGRKREQLI 1806
Query: 645 EQEVRLRQQEEKMQEHQEHL 664
E++++L Q+ E+ E L
Sbjct: 1807 EKKMKLAQKRERWINSMEEL 1826
Score = 165 bits (417), Expect = 1e-40
Identities = 130/506 (25%), Positives = 261/506 (51%), Gaps = 75/506 (14%)
Query: 219 LKEKNAKLQEKLQ--LVESEKSEIQLN--------VKELKRKLERAKLLLPQQQLQAEA- 267
LK+++ L E L +V EK I + ++ + +++ R K ++P+++ QA+
Sbjct: 1294 LKKESKVLLEDLDWDVVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQKK 1353
Query: 268 --DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
D LG E V K +V E N ++ K +EEK + +K +Q K +
Sbjct: 1354 ARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISK---KEEK--KTFQKSPKQGRKAVQ 1408
Query: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM-MWEKEEKIRELEE 384
+E K+ + + +M ++E M E+ E+M EE + ++E K+ +E W+ +K + +
Sbjct: 1409 KERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWK 1468
Query: 385 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
++H + + + K + E+++ ++E++ Q EK+ +EE ++E +K W + +
Sbjct: 1469 QVHGETRKSWKAWKEEWEKRLLQEEEKLHQAG------EKLSPEEEMLQEDKKLKWEEWK 1522
Query: 445 KIHEQ--EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW---- 498
++ E +E++ +++EE+ +EE RE EE KE+ +E+ QEE W
Sbjct: 1523 QVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEE----KEQQVTEEQRHIQEEHKWARIH 1578
Query: 499 ----RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMG 554
R E+K +E K+ ++EEK+ ++E ++ ++E K+ + KI + + M + E K
Sbjct: 1579 RKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFA 1638
Query: 555 EQEEKM-QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI------------------- 594
++EE + Q EK+ ++ EK+ ++ +K+ ++ EK+ +EEK+
Sbjct: 1639 QKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVE 1698
Query: 595 ----------WEQEEKIREQEEMMQEQEEKMWEQEE------KMCEQEEKMQEQEEKMRR 638
W+++E +E EE+ + EE W++EE K+ E+++K+ E+EE +
Sbjct: 1699 ELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAW 1758
Query: 639 QEEKMWEQEVRLRQQEEKMQEHQEHL 664
Q EK+ E+E +L Q+EE + + +E L
Sbjct: 1759 QREKLSEEETKLAQEEELLIQEKEKL 1784
Score = 149 bits (375), Expect = 1e-35
Identities = 142/596 (23%), Positives = 286/596 (47%), Gaps = 80/596 (13%)
Query: 107 PEDEQKASHQHQEALRRELEAQVHTIRILTCQK--TELQMALYYSQHAV---KQLEGEAR 161
PE+E++ + ++ + ++++ R + + T+ +M LY ++ K L E
Sbjct: 1792 PEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKE 1851
Query: 162 DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKE 221
L R + L + + K K + + L + + L+ E + T+ + KE
Sbjct: 1852 KLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQE--KETVIKK--KE 1907
Query: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP-QQQLQAEADHLGKELQSVSAK 280
K A+ ++KL VE ++ Q + + K KL K ++ +++L+ E D + KE ++++ +
Sbjct: 1908 KLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELD-IAKEEKALNLE 1966
Query: 281 LQAQVEEN----ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ---EEKIREQEEKIREQ 333
++ EE E L++ + + RQ + Q +E + + EEKI E++I
Sbjct: 1967 MKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAM 2026
Query: 334 EE----------------------KMRRQEEMMWEKEE-----------------KMRRQ 354
EE K+ + + +K E K+ R
Sbjct: 2027 EESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRD 2086
Query: 355 EEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 414
E + ++E KM +++ ++ KE ++ + K+ I+E + + E ++++K +
Sbjct: 2087 ERKLTQEEIKMTKMKRALFVKERRLSIEQSKLD----IKEWDFSEKRSELTKDEKKLARK 2142
Query: 415 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKI----HEQEKIREEEKRQEQEEMWRQEEK 470
+ K+ + ++ +EEK+ E+E K+ R+ ++ E+ I EEE + WR+ ++
Sbjct: 2143 QRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKE 2202
Query: 471 IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE 530
+ + + KEK Q + EE + E + D+ EK +E + +EE+ RE+EE
Sbjct: 2203 AKRGD---KPKEKFSSQVDEVESEEHFSEEMESLLDELEK----QESLSSEEEEEREEEE 2255
Query: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE---EKIREQEEKIREQKEKI 587
+ +EE++RE+EE +E+EE +Q EK +E++K +++E E+++E+EE E++E +
Sbjct: 2256 E--REEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313
Query: 588 REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 643
E+E + EE E+EE +EE E+E E++ K+QEQ K R E++
Sbjct: 2314 SEEETESLSDEE---EEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERV 2366
Score = 146 bits (368), Expect = 7e-35
Identities = 163/635 (25%), Positives = 308/635 (48%), Gaps = 91/635 (14%)
Query: 107 PEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISR 166
P+ EQ Q +E L +ELE + L+ ++ EL K+L E L +
Sbjct: 1701 PQREQNLDWQEKE-LAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQ 1759
Query: 167 LHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 226
+ +L Q + +K+K ++ E++ +E + L + E+L EK KL
Sbjct: 1760 REKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKR-------EQLIEKKMKL 1812
Query: 227 QEKLQLVESEKSEIQLNVKELKRKL----ERAKLLLPQQQLQAEADHL--GKELQSVSAK 280
+K + + E+ N L +K E+ L +++L ++L KE + S K
Sbjct: 1813 AQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKK 1872
Query: 281 LQAQVEEN-ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
QV+ ++N++ Q EEK+ +++E + + +EK+ E E+K+ + E+ + +++EK+ +
Sbjct: 1873 QLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQ 1932
Query: 340 QE-EMMWEK---EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ 395
++ ++ EK + K R + E+ KEEK LE M EEK+R +E K K
Sbjct: 1933 EKMKLALEKAMVQGKKRLRGELDIAKEEKALNLE-MKRLAEEKMRLVEGK-ETLSKGETP 1990
Query: 396 EEKRQEEEKIREQE---KRQEQEAKMWRQEEKIREQEE---------------------- 430
E RQ + EQE ++ E K+ E++I EE
Sbjct: 1991 ETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQR 2050
Query: 431 KIREQEKKMWRQEEKIHEQ-----------EKIREEEKRQEQEE---------MWRQEEK 470
K+ + +K+ ++ E + ++ +K+ +E++ QEE ++ +E +
Sbjct: 2051 KLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERR 2110
Query: 471 IR-EQEEI----WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525
+ EQ ++ W EK E + K E+K+ R++ K+ ++ ++ +EEKM +E K+
Sbjct: 2111 LSIEQSKLDIKEWDFSEKRSE---LTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKL 2167
Query: 526 -REQEEKIREQEEK--IREQE-------EMMQEQEEKMGEQ-EEKMQEQEKMRRQEEKIR 574
R+ E I + EE+ I E+E + +E K G++ +EK Q EE
Sbjct: 2168 ARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFS 2227
Query: 575 EQEEKI---REQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ--EEKMCEQEEKM 629
E+ E + E++E + +EE+ E+EE+ RE+EE+ +E+EE+ E+ EEK E+EE+
Sbjct: 2228 EEMESLLDELEKQESLSSEEEEEREEEEE-REEEEVREEEEERKEEEEGEEKQVEKEEEE 2286
Query: 630 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
+++++K +++EE ++EV ++E +E E L
Sbjct: 2287 KKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL 2321
Score = 143 bits (360), Expect = 6e-34
Identities = 156/587 (26%), Positives = 292/587 (49%), Gaps = 90/587 (15%)
Query: 154 KQLEGEARDLISRLHD-SWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRN 212
K+L E +L + + SWK EL Q + +KKK E L +R+ LS E +
Sbjct: 1712 KELAQELEELEWDMEELSWK-EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKL 1770
Query: 213 TITDEEL---KEKNAKLQEKL------------QLVE-----SEKSEIQLNVKELKRKLE 252
+E L KEK A+ +EK+ QL+E ++K E +N E +L
Sbjct: 1771 AQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSME---ELT 1827
Query: 253 RAKLLLPQQQ-LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK--- 308
+ K++L Q++ L E +L +E + + AQ +EN L+N+ +K Q +
Sbjct: 1828 KNKMILYQKKNLAQEKKNLAQEKEKL-----AQRKENLLYNKERLTHSKKQLVQVKNKLG 1882
Query: 309 -----IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
+ + EEK+ +++E + +++EK+ E E+K+ + E+ + +K+EK+ QE+M E+
Sbjct: 1883 MFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLA-QEKMKLALEK 1941
Query: 364 KM----RRLE-EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 418
M +RL E+ KEEK LE K +EK+R E K + + RQ KM
Sbjct: 1942 AMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQR---KM 1998
Query: 419 WRQEEKIREQ----EEKIREQEKKMWRQEEKIHEQEKIREEEKR----QEQEEMWRQEEK 470
+ E+++ E+ EEKI E ++ EE + K+ + Q Q ++ + K
Sbjct: 1999 TQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRK 2058
Query: 471 -IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQE 529
I+++E + ++ K++ KI K +K+ R E K+ +E K+ + + ++ +E ++ ++
Sbjct: 2059 LIKKRESLSKEPAKLN---KILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQ 2115
Query: 530 EKIREQEEKIREQEEMMQEQEEKMGEQEEKM-QEQEKMRRQEEKIREQEEKI-REQKEKI 587
K+ +E E+ + + E+K+ ++ K+ + +M +EEK+ E+E K+ R+ E I
Sbjct: 2116 SKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVI 2175
Query: 588 REQEEKIWEQEEKI--------REQEEMMQ---------------EQEEKMWEQEEKMC- 623
+ EE+ +EE++ R+++E + E EE E+ E +
Sbjct: 2176 LDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLD 2235
Query: 624 --EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
E++E + +EE+ R +EE+ E+EVR ++EE+ +E +E E +
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVR--EEEEERKEEEEGEEKQV 2280
Score = 138 bits (348), Expect = 1e-32
Identities = 102/453 (22%), Positives = 255/453 (56%), Gaps = 43/453 (9%)
Query: 216 DEELKEKNAKL-QEKLQLVESEKSEIQLNVKELKRKLERA----KLLLPQQQLQAEADHL 270
+ +L ++ KL QE+ QL + E+ Q VK + E A K ++ L + L
Sbjct: 1592 ERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKL 1651
Query: 271 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
+E + ++ K + ++ W ++ ++EEK+ ++ K+ E + + ++ E++ ++E+ +
Sbjct: 1652 SQEAEKLAQKRKKLAKK---WEKV-AREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL 1707
Query: 331 REQEEKMRRQ-EEMMWEKEEKMRRQEEMMWEK----EEKMRRLEE---MMWEKEE----- 377
QE+++ ++ EE+ W+ EE ++EE+ E+ EEK + EE + W++E+
Sbjct: 1708 DWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEE 1767
Query: 378 -KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436
K+ + EE + I+E+E+ Q +EK+ E+E+R + R+ E++ E++ K+ ++
Sbjct: 1768 TKLAQEEELL-----IQEKEKLAQHKEKMPEEEER------LGRKREQLIEKKMKLAQKR 1816
Query: 437 KKMWRQEEKIHEQEKIREEEKR--QEQEEMWRQEEKIREQEE--IWRQKEKMHEQEKIRK 492
++ E++ + + I ++K QE++ + +++EK+ +++E ++ ++ H ++++ +
Sbjct: 1817 ERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQ 1876
Query: 493 QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEK 552
+ K+ + + EEK+ +++E + +++EK+ E E+K+ + E+ + +++E + +++ K
Sbjct: 1877 VKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMK 1936
Query: 553 MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612
+ E+ M + +K R E I ++E+ + + +++ E++ ++ E +E + + E ++
Sbjct: 1937 LA-LEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQ 1995
Query: 613 EKMWEQEEKMCEQ----EEKMQEQEEKMRRQEE 641
KM + E+++ E+ EEK+ E+++ EE
Sbjct: 1996 RKMTQVEQELFERKLSLEEKILLHEDRILAMEE 2028
Score = 136 bits (342), Expect = 7e-32
Identities = 96/405 (23%), Positives = 221/405 (54%), Gaps = 46/405 (11%)
Query: 298 QEEKMWRQEEKIQEWEEKIQE-QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM----- 351
+++ ++ QE I+E + IQ +E IR +E RE+E+ ++ +M+ +E ++
Sbjct: 1313 EKKPIFIQEGAIRE--DMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKG 1370
Query: 352 ------------------RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK-- 391
+++E+ ++K K R +KE K+ +++ +M ++E+
Sbjct: 1371 KKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAV---QKERKVGKIKREMTKEERDM 1427
Query: 392 IREQEEKRQEEEKIREQEKR--QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 449
E EE EEK+ +QE + + W+ +K ++ +++ + +K W+ ++ E+
Sbjct: 1428 SEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEK 1487
Query: 450 EKIREEEK-RQEQEEMWRQEEKIREQEEI-WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
++EEEK Q E++ +EE ++E +++ W + +++ E K +E+ ++ EE++ +
Sbjct: 1488 RLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLE 1547
Query: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIR------EQEEMMQEQEEKMGEQEEKMQ 561
EE RE EEK E+++ E++ I+E+ + R E+ ++E K+ ++EEK+
Sbjct: 1548 EEVSREGEEK----EQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLA 1603
Query: 562 EQEKMRRQEE-KIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
++E+ QEE K+ + KI + ++ + E K ++EE + ++ E + ++ EK+ ++ +
Sbjct: 1604 QEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRK 1663
Query: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
K+ ++ EK+ +EEK+ ++ K+ E + L Q+ E++ + +++L+
Sbjct: 1664 KLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLD 1708
Score = 115 bits (287), Expect = 2e-25
Identities = 121/554 (21%), Positives = 259/554 (46%), Gaps = 84/554 (15%)
Query: 188 KKKADRYIEEL--TKERDALSLELYRNTITDE--------ELKEKNA-----------KL 226
KK + +++ L TKERD+ + + DE E++E + KL
Sbjct: 1090 KKHSQKWLRGLKKTKERDSKQMSTEPGLLEDESGTEAAPIEMEEASVYSQWSSSTSVIKL 1149
Query: 227 QEKLQLVESE--KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 284
+ + E + K I L +K L++ ++ Q+L+ + GKE + ++ +
Sbjct: 1150 SKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKKKHKKKGKEAKVINEETTPP 1209
Query: 285 VEENELWNRLNQQQEEKMWRQEEKI-----QEWEEKI-QEQEEKIREQEEKIREQ--EEK 336
V E + ++ Q + W + + + +I + K+ E E
Sbjct: 1210 VMEQPVTKKVKIQGRGASGISGRRSTAGDGSSWRDDLCRLMALRISGSQTKMSENLNAEL 1269
Query: 337 MRRQEEMMWEKEEKMRRQEEM--MWEKEEKMRRLEEMMWE---KEEKIRELEEKMHEQEK 391
+ +EM+ ++ +E+ + +KE K+ LE++ W+ E+K ++E ++
Sbjct: 1270 VTFAQEMLVDRHPSWELFQEICPLLKKESKVL-LEDLDWDVVPPEKKPIFIQEGAIREDM 1328
Query: 392 IR--EQEEKRQEEEKIREQEKRQEQEAKMWRQEEK--IREQEEKI--------------- 432
I+ QE R +E RE+E+ Q++ M EE I ++ +K+
Sbjct: 1329 IQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEIS 1388
Query: 433 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK 492
+++EKK +++ K + +E + + + EM ++E + E+ E E +EK+ K
Sbjct: 1389 KKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVE-----EMATLEEKVVK 1443
Query: 493 QEEKV--------WRQEEKMHDQEEKIREQEEKMWRQ-----EEKIREQEEKIREQEEKI 539
QE K+ W+ +K D+ +++ + K W+ E+++ ++EEK+ + EK+
Sbjct: 1444 QEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKL 1503
Query: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
+EEM+QE ++ E+ +++ E + +E+ + EE++ ++E RE EEK E+
Sbjct: 1504 SPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEK----EQ 1559
Query: 600 KIREQEEMMQEQEE------KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 653
++ E++ +QE+ + K E+K ++E K+ ++EEK+ ++E ++ ++E +L Q
Sbjct: 1560 QVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQA 1619
Query: 654 EEKMQEHQEHLEAA 667
K+ + + A
Sbjct: 1620 YVKITQDDREMAQA 1633
Score = 52.8 bits (125), Expect = 1e-06
Identities = 54/252 (21%), Positives = 123/252 (48%), Gaps = 34/252 (13%)
Query: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
+ K+ D+ E+ + + D + E E E+ L ++L+ ES SE + +E
Sbjct: 2202 EAKRGDKPKEKFSSQVDEVESE--------EHFSEEMESLLDELEKQESLSSEEE---EE 2250
Query: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE 306
+ + ER + + +++ + + + G+E QVE+ E +++++K +++
Sbjct: 2251 REEEEEREEEEVREEEEERKEEEEGEE---------KQVEKEE-----EEKKKKKKEKKK 2296
Query: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
E++QE EE +E+EE + E+E + EE +EE EE++ R++E++ K+EK
Sbjct: 2297 EEVQEKEEVFEEKEEIMSEEETESLSDEE----EEEESCSLEEEVDREKEIL--KKEKQF 2350
Query: 367 RLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 426
+L+E ++ + +R E + + + + ++ K+ A +++ +
Sbjct: 2351 KLQE---QRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVP 2407
Query: 427 EQEEKIREQEKK 438
E++I ++KK
Sbjct: 2408 VPEKQISWEDKK 2419
Score = 38.1 bits (87), Expect = 0.026
Identities = 53/255 (20%), Positives = 124/255 (48%), Gaps = 25/255 (9%)
Query: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEG---EARDLI 164
+DE+K + + Q L ++ ++ +T + E ++A +S+ + E E ++I
Sbjct: 2134 KDEKKLARK-QRKLANKMRRMINKEEKMT--EEESKLARKHSEVILDDEEEGGIEEEEVI 2190
Query: 165 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE-ELKEKN 223
L W+ E ++ K+K ++E+ E + S E+ ++ DE E +E
Sbjct: 2191 PFLKRRWRKRKEAKRG----DKPKEKFSSQVDEVESE-EHFSEEM--ESLLDELEKQESL 2243
Query: 224 AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQA 283
+ +E+ + E E+ E ++ +E +RK E ++Q++ E + K+ + K +
Sbjct: 2244 SSEEEEEREEEEEREEEEVREEEEERKEEEEG---EEKQVEKEEEEKKKKKKE---KKKE 2297
Query: 284 QVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 343
+V+E E + +++EE M EE+ + ++ +E+E E+E ++ K +Q ++
Sbjct: 2298 EVQEKE---EVFEEKEEIM--SEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKL 2352
Query: 344 MWEKEEKMRRQEEMM 358
++ + +R +E ++
Sbjct: 2353 QEQRRKSLRGRERVL 2367
>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
subfamily a-like [Homo sapiens]
Length = 432
Score = 174 bits (442), Expect = 2e-43
Identities = 131/435 (30%), Positives = 220/435 (50%), Gaps = 90/435 (20%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP HP MS++T+Q KLA AK++L + + +P + A+ +KKK+N G++P+T TSG
Sbjct: 5 PRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGAN--RKKKVN-GSSPDTATSG 61
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
G HSP D + GE R
Sbjct: 62 GYHSPGDSATGIY------------------------------------------GEGRA 79
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
+ L D LE +A + I +LT+ ++L T +E K+
Sbjct: 80 SSTTLQD-------LESQYQELAVALDSSSAIISQLTENINSL-------VRTSKEEKKH 125
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--------QQLQAEADHLGKEL 274
L +KL K K + A+ L PQ +QLQ E +HL KEL
Sbjct: 126 EIHLVQKL------------GRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKEL 173
Query: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
+SV +LQA+VE N++ + LN++QEE++ QEE+++E EE++ EQEE++ EQEE++REQE
Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQE 233
Query: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE 394
E++ QE++ + E + E+++ K+E+ + +E + E+E + E+EE + EQE++R+
Sbjct: 234 ERLCEQEKLPGQ-ERLLEEVEKLL--KQERRQEEQERLLERERLLDEVEELL-EQERLRQ 289
Query: 395 QEEKRQEEEKIREQEKRQEQE-------AKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Q+E+ ++E +RE E+ +E E ++ Q + R E++ + K + E+++
Sbjct: 290 QDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVK 349
Query: 448 EQEKIREEEKRQEQE 462
E EK E+ + E
Sbjct: 350 ELEKSGGAEEPRGSE 364
Score = 115 bits (288), Expect = 1e-25
Identities = 64/186 (34%), Positives = 118/186 (63%), Gaps = 14/186 (7%)
Query: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK 531
+E E + RQ + E ++ + RQEE++ +QEE++REQEE++ QEE++ EQEE+
Sbjct: 171 KELESVGRQLQAEVENNQMLSLLNR--RQEERLREQEERLREQEERLCEQEERLCEQEER 228
Query: 532 IREQEEKIREQE-----EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK 586
+REQEE++ EQE E + E+ EK+ +QE + +EQE++ +E + E EE + ++E+
Sbjct: 229 LREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELL--EQER 286
Query: 587 IREQEEKIWEQE-----EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
+R+Q+E++W+QE E++RE E M++ E ++EQ + E++ + + + E+
Sbjct: 287 LRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQ 346
Query: 642 KMWEQE 647
++ E E
Sbjct: 347 QVKELE 352
Score = 110 bits (274), Expect = 5e-24
Identities = 80/315 (25%), Positives = 160/315 (50%), Gaps = 36/315 (11%)
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Q L+++ L L S SA + E R ++++++ +K+ K++ Q
Sbjct: 85 QDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQT 144
Query: 321 -EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379
E + Q + E+++ + + ++ E + RQ + E + + L
Sbjct: 145 AEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR--------- 195
Query: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ-EQEAKMWRQEEKIREQEEKIREQEKK 438
R++E R++EE++REQE+R EQE ++ QEE++REQEE++ EQE K
Sbjct: 196 -------------RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQE-K 241
Query: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498
+ QE + E EK+ ++E+RQE ++E++ E+E + + E++ EQE++R+Q+E++W
Sbjct: 242 LPGQERLLEEVEKLLKQERRQE------EQERLLERERLLDEVEELLEQERLRQQDERLW 295
Query: 499 RQE-----EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
+QE E++ + E + E ++ Q + R E++ + + + E+ ++E E+
Sbjct: 296 QQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSG 355
Query: 554 GEQEEKMQEQEKMRR 568
G +E + E R
Sbjct: 356 GAEEPRGSESAAAAR 370
Score = 110 bits (274), Expect = 5e-24
Identities = 73/237 (30%), Positives = 134/237 (56%), Gaps = 25/237 (10%)
Query: 444 EKIHEQEKIREEEKRQE---QEEMWRQEEKIREQ--EEIWRQ--------KEKMHEQEKI 490
E I+ + +EEK+ E +++ R K++ Q E + Q ++ E +
Sbjct: 110 ENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHL 169
Query: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQE 550
RK+ E V RQ + + + + RQEE++REQEE++REQEE++ EQEE + EQE
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNR---RQEERLREQEERLREQEERLCEQEERLCEQE 226
Query: 551 EKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ- 609
E++ EQEE++ EQEK+ QE + E E+ +++ E+ +E++E++ E+E + E EE+++
Sbjct: 227 ERLREQEERLCEQEKLPGQERLLEEVEKLLKQ--ERRQEEQERLLERERLLDEVEELLEQ 284
Query: 610 ----EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
+Q+E++W+QE + E+++E E + E ++EQ R E++ +
Sbjct: 285 ERLRQQDERLWQQE--TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENK 339
Score = 99.0 bits (245), Expect = 1e-20
Identities = 67/263 (25%), Positives = 142/263 (53%), Gaps = 32/263 (12%)
Query: 383 EEKMHEQEKIREQEE-----KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 437
EEK HE +++ K Q E + Q + E+++++ +R++ +
Sbjct: 121 EEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKV------EQLQDETNHLRKELE 174
Query: 438 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKV 497
+ RQ + E ++ R+++E + QEE++REQE E++ +QEE++
Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQE------------ERLCEQEERL 222
Query: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE 557
QEE++ +QEE++ EQE+ +E++ E+ EK+ +QE + EQE ++ + E++ ++
Sbjct: 223 CEQEERLREQEERLCEQEK--LPGQERLLEEVEKLLKQERRQEEQERLL--ERERLLDEV 278
Query: 558 EKMQEQEKMRRQEEKIREQE-----EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612
E++ EQE++R+Q+E++ +QE E++RE + + E ++EQ + R E + +
Sbjct: 279 EELLEQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNEN 338
Query: 613 EKMWEQEEKMCEQEEKMQEQEEK 635
+ + E+++ E E+ +E +
Sbjct: 339 KSTLQLEQQVKELEKSGGAEEPR 361
Score = 97.8 bits (242), Expect = 3e-20
Identities = 61/178 (34%), Positives = 109/178 (61%), Gaps = 16/178 (8%)
Query: 500 QEEKMHDQE--EKIREQEEKMWRQE-EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556
+EEK H+ +K+ K+ Q E + Q + E+++++ ++++ E +G Q
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 557 EEKMQEQEKM-----RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQ 611
+ E +M RRQEE++REQEE++REQ+E++ EQEE++ EQEE++REQEE + EQ
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQ 239
Query: 612 E-----EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
E E++ E+ EK+ +QE + +EQE + R E++ ++ L +QE ++++ E L
Sbjct: 240 EKLPGQERLLEEVEKLLKQERRQEEQERLLER--ERLLDEVEELLEQE-RLRQQDERL 294
Score = 62.0 bits (149), Expect = 2e-09
Identities = 41/163 (25%), Positives = 81/163 (49%), Gaps = 12/163 (7%)
Query: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
+ D E + +E + I + E I +E+++ +K+G K++ Q
Sbjct: 84 LQDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQ 143
Query: 564 --EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
E + Q + E+++++ +R++ E + Q + E +M+ +
Sbjct: 144 TAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRR------- 196
Query: 622 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
QEE+++EQEE++R QEE++ EQE RL +QEE+++E +E L
Sbjct: 197 ---QEERLREQEERLREQEERLCEQEERLCEQEERLREQEERL 236
>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
Length = 432
Score = 174 bits (442), Expect = 2e-43
Identities = 131/435 (30%), Positives = 220/435 (50%), Gaps = 90/435 (20%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP HP MS++T+Q KLA AK++L + + +P + A+ +KKK+N G++P+T TSG
Sbjct: 5 PRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGAN--RKKKVN-GSSPDTATSG 61
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
G HSP D + GE R
Sbjct: 62 GYHSPGDSATGIY------------------------------------------GEGRA 79
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
+ L D LE +A + I +LT+ ++L T +E K+
Sbjct: 80 SSTTLQD-------LESQYQELAVALDSSSAIISQLTENINSL-------VRTSKEEKKH 125
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--------QQLQAEADHLGKEL 274
L +KL K K + A+ L PQ +QLQ E +HL KEL
Sbjct: 126 EIHLVQKL------------GRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKEL 173
Query: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
+SV +LQA+VE N++ + LN++QEE++ QEE+++E EE++ EQEE++ EQEE++REQE
Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQE 233
Query: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE 394
E++ QE++ + E + E+++ K+E+ + +E + E+E + E+EE + EQE++R+
Sbjct: 234 ERLCEQEKLPGQ-ERLLEEVEKLL--KQERRQEEQERLLERERLLDEVEELL-EQERLRQ 289
Query: 395 QEEKRQEEEKIREQEKRQEQE-------AKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Q+E+ ++E +RE E+ +E E ++ Q + R E++ + K + E+++
Sbjct: 290 QDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVK 349
Query: 448 EQEKIREEEKRQEQE 462
E EK E+ + E
Sbjct: 350 ELEKSGGAEEPRGSE 364
Score = 115 bits (288), Expect = 1e-25
Identities = 64/186 (34%), Positives = 118/186 (63%), Gaps = 14/186 (7%)
Query: 472 REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK 531
+E E + RQ + E ++ + RQEE++ +QEE++REQEE++ QEE++ EQEE+
Sbjct: 171 KELESVGRQLQAEVENNQMLSLLNR--RQEERLREQEERLREQEERLCEQEERLCEQEER 228
Query: 532 IREQEEKIREQE-----EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK 586
+REQEE++ EQE E + E+ EK+ +QE + +EQE++ +E + E EE + ++E+
Sbjct: 229 LREQEERLCEQEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELL--EQER 286
Query: 587 IREQEEKIWEQE-----EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
+R+Q+E++W+QE E++RE E M++ E ++EQ + E++ + + + E+
Sbjct: 287 LRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQ 346
Query: 642 KMWEQE 647
++ E E
Sbjct: 347 QVKELE 352
Score = 110 bits (274), Expect = 5e-24
Identities = 80/315 (25%), Positives = 160/315 (50%), Gaps = 36/315 (11%)
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Q L+++ L L S SA + E R ++++++ +K+ K++ Q
Sbjct: 85 QDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQT 144
Query: 321 -EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379
E + Q + E+++ + + ++ E + RQ + E + + L
Sbjct: 145 AEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR--------- 195
Query: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ-EQEAKMWRQEEKIREQEEKIREQEKK 438
R++E R++EE++REQE+R EQE ++ QEE++REQEE++ EQE K
Sbjct: 196 -------------RQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQE-K 241
Query: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498
+ QE + E EK+ ++E+RQE ++E++ E+E + + E++ EQE++R+Q+E++W
Sbjct: 242 LPGQERLLEEVEKLLKQERRQE------EQERLLERERLLDEVEELLEQERLRQQDERLW 295
Query: 499 RQE-----EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
+QE E++ + E + E ++ Q + R E++ + + + E+ ++E E+
Sbjct: 296 QQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSG 355
Query: 554 GEQEEKMQEQEKMRR 568
G +E + E R
Sbjct: 356 GAEEPRGSESAAAAR 370
Score = 110 bits (274), Expect = 5e-24
Identities = 73/237 (30%), Positives = 134/237 (56%), Gaps = 25/237 (10%)
Query: 444 EKIHEQEKIREEEKRQE---QEEMWRQEEKIREQ--EEIWRQ--------KEKMHEQEKI 490
E I+ + +EEK+ E +++ R K++ Q E + Q ++ E +
Sbjct: 110 ENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHL 169
Query: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQE 550
RK+ E V RQ + + + + RQEE++REQEE++REQEE++ EQEE + EQE
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNR---RQEERLREQEERLREQEERLCEQEERLCEQE 226
Query: 551 EKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ- 609
E++ EQEE++ EQEK+ QE + E E+ +++ E+ +E++E++ E+E + E EE+++
Sbjct: 227 ERLREQEERLCEQEKLPGQERLLEEVEKLLKQ--ERRQEEQERLLERERLLDEVEELLEQ 284
Query: 610 ----EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
+Q+E++W+QE + E+++E E + E ++EQ R E++ +
Sbjct: 285 ERLRQQDERLWQQE--TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENK 339
Score = 99.0 bits (245), Expect = 1e-20
Identities = 67/263 (25%), Positives = 142/263 (53%), Gaps = 32/263 (12%)
Query: 383 EEKMHEQEKIREQEE-----KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 437
EEK HE +++ K Q E + Q + E+++++ +R++ +
Sbjct: 121 EEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKV------EQLQDETNHLRKELE 174
Query: 438 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKV 497
+ RQ + E ++ R+++E + QEE++REQE E++ +QEE++
Sbjct: 175 SVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQE------------ERLCEQEERL 222
Query: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE 557
QEE++ +QEE++ EQE+ +E++ E+ EK+ +QE + EQE ++ + E++ ++
Sbjct: 223 CEQEERLREQEERLCEQEK--LPGQERLLEEVEKLLKQERRQEEQERLL--ERERLLDEV 278
Query: 558 EKMQEQEKMRRQEEKIREQE-----EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612
E++ EQE++R+Q+E++ +QE E++RE + + E ++EQ + R E + +
Sbjct: 279 EELLEQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNEN 338
Query: 613 EKMWEQEEKMCEQEEKMQEQEEK 635
+ + E+++ E E+ +E +
Sbjct: 339 KSTLQLEQQVKELEKSGGAEEPR 361
Score = 97.8 bits (242), Expect = 3e-20
Identities = 61/178 (34%), Positives = 109/178 (61%), Gaps = 16/178 (8%)
Query: 500 QEEKMHDQE--EKIREQEEKMWRQE-EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556
+EEK H+ +K+ K+ Q E + Q + E+++++ ++++ E +G Q
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 557 EEKMQEQEKM-----RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQ 611
+ E +M RRQEE++REQEE++REQ+E++ EQEE++ EQEE++REQEE + EQ
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQ 239
Query: 612 E-----EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
E E++ E+ EK+ +QE + +EQE + R E++ ++ L +QE ++++ E L
Sbjct: 240 EKLPGQERLLEEVEKLLKQERRQEEQERLLER--ERLLDEVEELLEQE-RLRQQDERL 294
Score = 62.0 bits (149), Expect = 2e-09
Identities = 41/163 (25%), Positives = 81/163 (49%), Gaps = 12/163 (7%)
Query: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
+ D E + +E + I + E I +E+++ +K+G K++ Q
Sbjct: 84 LQDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQ 143
Query: 564 --EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
E + Q + E+++++ +R++ E + Q + E +M+ +
Sbjct: 144 TAEPLAPQPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRR------- 196
Query: 622 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
QEE+++EQEE++R QEE++ EQE RL +QEE+++E +E L
Sbjct: 197 ---QEERLREQEERLREQEERLCEQEERLCEQEERLREQEERL 236
>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 432
Score = 172 bits (437), Expect = 7e-43
Identities = 138/460 (30%), Positives = 223/460 (48%), Gaps = 108/460 (23%)
Query: 43 PHLPTHPMMSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSG 102
P LP HP MS++T+Q KLA AK++L + + +P + A+ +KKK+N G++P+T TSG
Sbjct: 5 PRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGAN--RKKKVN-GSSPDTATSG 61
Query: 103 GCHSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARD 162
G HSP D + GE R
Sbjct: 62 GYHSPGDSATGIY------------------------------------------GEGRA 79
Query: 163 LISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK 222
+ L D LE +A + I +LT+ ++L T +E K+
Sbjct: 80 SSTTLQD-------LESQYQELAVALDSSSAIISQLTENINSL-------VRTSKEEKKH 125
Query: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--------QQLQAEADHLGKEL 274
L +KL K K + A+ L P+ +QLQ E +HL KEL
Sbjct: 126 EIHLVQKL------------GRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKEL 173
Query: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334
+SV +LQA+VE N++ + LN++QEE++ QEE+++E EE++ EQEE++ EQEE++ EQE
Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQE 233
Query: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE 394
E++ Q EK+ QE ++ E+ EK+ E E + EQE++ E
Sbjct: 234 ERLCEQ--------EKLPGQERLL---------------EEVEKLLEQERRQEEQERLLE 270
Query: 395 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 454
+E E E++ EQE+ ++Q+ ++W Q+E +RE E++RE E+ + E ++EQ
Sbjct: 271 RERLLDEVEELLEQERLRQQDERLW-QQETLREL-ERLRELERMLELGWEALYEQ----R 324
Query: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE 494
E R EE+ + + + E+ ++ EK E+ R E
Sbjct: 325 AEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPRGSE 364
Score = 110 bits (276), Expect = 3e-24
Identities = 65/182 (35%), Positives = 113/182 (62%), Gaps = 12/182 (6%)
Query: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
E +RK+ E V RQ + + + + RQEE++REQEE++REQEE++ EQEE
Sbjct: 165 ETNHLRKELESVGRQLQAEVENNQMLSLLNR---RQEERLREQEERLREQEERLHEQEER 221
Query: 546 MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQE 605
+ EQEE++ EQEE++ EQEK+ Q E++ E+ EK+ EQ E+ +E++E++ E+E + E E
Sbjct: 222 LCEQEERLCEQEERLCEQEKLPGQ-ERLLEEVEKLLEQ-ERRQEEQERLLERERLLDEVE 279
Query: 606 EMMQ-----EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660
E+++ +Q+E++W+QE + E+++E E + E ++EQ R E++
Sbjct: 280 ELLEQERLRQQDERLWQQE--TLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNE 337
Query: 661 QE 662
+
Sbjct: 338 NK 339
Score = 108 bits (271), Expect = 1e-23
Identities = 64/206 (31%), Positives = 122/206 (59%), Gaps = 18/206 (8%)
Query: 374 EKEEKIRELEEKMHEQEKI-----REQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIRE 427
E E R+L+ ++ + + R++E R++EE++REQE+R EQE ++ QEE++ E
Sbjct: 172 ELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEERLCE 231
Query: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487
QEE++ EQEK + QE + E EK+ E+E+RQE++E ++ E+E + + E++ EQ
Sbjct: 232 QEERLCEQEK-LPGQERLLEEVEKLLEQERRQEEQE------RLLERERLLDEVEELLEQ 284
Query: 488 EKIRKQEEKVWRQE-----EKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542
E++R+Q+E++W+QE E++ + E + E ++ Q + R E++ + + +
Sbjct: 285 ERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQL 344
Query: 543 EEMMQEQEEKMGEQEEKMQEQEKMRR 568
E+ ++E E+ G +E + E R
Sbjct: 345 EQQVKELEKSGGAEEPRGSESAAAAR 370
Score = 103 bits (258), Expect = 4e-22
Identities = 64/180 (35%), Positives = 111/180 (61%), Gaps = 19/180 (10%)
Query: 500 QEEKMHDQE--EKIREQEEKMWRQE-EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556
+EEK H+ +K+ K+ Q E + + + E+++++ ++++ E +G Q
Sbjct: 120 KEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQ 179
Query: 557 EEKMQEQEKM-----RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQ 611
+ E +M RRQEE++REQEE++REQ+E++ EQEE++ EQEE++ EQEE + EQ
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQ 239
Query: 612 E-----EKMWEQEEKMCEQEEKMQEQEEKMRRQE-----EKMWEQEVRLRQQEEKMQEHQ 661
E E++ E+ EK+ EQE + +EQE + R+ E++ EQE RLRQQ+E++ + +
Sbjct: 240 EKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQE-RLRQQDERLWQQE 298
Score = 101 bits (251), Expect = 3e-21
Identities = 75/300 (25%), Positives = 160/300 (53%), Gaps = 32/300 (10%)
Query: 352 RRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE--EKI-REQ 408
R + + E + + L + I +L E ++ + ++E+K + +K+ R
Sbjct: 78 RASSTTLQDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSL 137
Query: 409 EKRQEQEAKMWRQE--------EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 460
K + Q A+ E E+++++ +R++ + + RQ + E ++ R++
Sbjct: 138 FKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQ 197
Query: 461 QEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR 520
+E + QEE++REQE E++HE QEE++ QEE++ +QEE++ EQE+
Sbjct: 198 EERLREQEERLREQE------ERLHE------QEERLCEQEERLCEQEERLCEQEK--LP 243
Query: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQE--- 577
+E++ E+ EK+ EQE + EQE ++ + E++ ++ E++ EQE++R+Q+E++ +QE
Sbjct: 244 GQERLLEEVEKLLEQERRQEEQERLL--ERERLLDEVEELLEQERLRQQDERLWQQETLR 301
Query: 578 --EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 635
E++RE + + E ++EQ + R E + + + + E+++ E E+ +E +
Sbjct: 302 ELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPR 361
Score = 100 bits (248), Expect = 6e-21
Identities = 77/284 (27%), Positives = 154/284 (54%), Gaps = 22/284 (7%)
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Q L+++ L L S SA + E R ++++++ +K+ K++ Q
Sbjct: 85 QDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQT 144
Query: 321 -EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM----RRLEEMMWEK 375
E + + + E+++ + + ++ E + RQ + E + + RR EE + E+
Sbjct: 145 AEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQ 204
Query: 376 EEKIRELEEKMHEQ-EKIREQEEKR-QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
EE++RE EE++HEQ E++ EQEE+ ++EE++ EQEK Q E++ E+ EK+
Sbjct: 205 EERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQ--------ERLLEEVEKLL 256
Query: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
EQE+ RQE EQE++ E E+ ++ E ++E++R+Q+E Q+E + E E++R+
Sbjct: 257 EQER---RQE----EQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELERLREL 309
Query: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE 537
E + E +++Q + R E++ + + + E++++E E+
Sbjct: 310 ERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEK 353
Score = 99.4 bits (246), Expect = 1e-20
Identities = 71/231 (30%), Positives = 128/231 (55%), Gaps = 42/231 (18%)
Query: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ--EKIRKQEEKVWRQE 501
E I+ + +EEK+ E I +++ R K+ Q E + + +
Sbjct: 110 ENINSLVRTSKEEKKHE----------IHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKV 159
Query: 502 EKMHDQEEKIREQEEKMWRQEEKIREQEEKI----REQEEKIREQEEMMQEQEEKMGEQE 557
E++ D+ +R++ E + RQ + E + + R QEE++REQEE ++EQEE++ EQE
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLHEQE 219
Query: 558 EKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE-----EKIWEQEEKIREQEEMMQEQE 612
E++ EQEE++ EQ+E++ EQE E++ E+ EK+ EQE QE++
Sbjct: 220 ERLC-------------EQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQER-RQEEQ 265
Query: 613 EKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV-----RLRQQEEKMQ 658
E++ E+E + E EE + ++E++R+Q+E++W+QE RLR+ E ++
Sbjct: 266 ERLLERERLLDEVEELL--EQERLRQQDERLWQQETLRELERLRELERMLE 314
Score = 65.1 bits (157), Expect = 2e-10
Identities = 41/161 (25%), Positives = 84/161 (52%), Gaps = 5/161 (3%)
Query: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
+ D E + +E + I + E I +E+++ +K+G K++ Q
Sbjct: 84 LQDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQ 143
Query: 564 --EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
E + + + E+++++ +R++ E + Q + E +M+ + QEE+
Sbjct: 144 TAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRR---QEER 200
Query: 622 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
+ EQEE+++EQEE++ QEE++ EQE RL +QEE++ E ++
Sbjct: 201 LREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEK 241
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 149 bits (376), Expect = 8e-36
Identities = 156/562 (27%), Positives = 267/562 (47%), Gaps = 121/562 (21%)
Query: 211 RNTITDEELKEKNAKLQ----EKLQLVESEKSEIQLNVKELKRKLERAK----------L 256
+N++ DEE K Q ++ +E + K L+ LER K L
Sbjct: 71 QNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASL 130
Query: 257 LLPQQQLQ---AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ-EEKIQEW 312
LP +++Q AE + KE +S S + + ++EE E + Q+ + WR EE +E
Sbjct: 131 SLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND---WRDAEENKKED 187
Query: 313 EEKIQEQEEK-----IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367
+EK +E+EEK I E + ++ +E+ QEE + + + E ++EE+ +
Sbjct: 188 KEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQG 247
Query: 368 LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ-----EEEKIREQEKRQEQEAKMWRQE 422
+E+ EK+ E +++ E E+ R + E+R+ +++KI ++ R E E K QE
Sbjct: 248 SDEI--SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQE 305
Query: 423 EKIREQEEK--IREQEKKMWRQEEKIHEQEK--------IREEEKRQEQEEMWRQEEKIR 472
+ RE EE+ +RE+EK+ + ++I E+EK I+EEEKR +E +EE+ R
Sbjct: 306 RERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 365
Query: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQ-EEKMHDQEE------KIREQEEKMWRQEEKI 525
EE RQ+ + E+EK + +E+K +Q EEK H +E K+ ++ E W E+K
Sbjct: 366 AAEE--RQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKA 423
Query: 526 REQE---------------------EKIRE----------QEEKIREQEEMMQE----QE 550
+E + EK++E ++EKI++ +E +E +
Sbjct: 424 QEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMD 483
Query: 551 EKMGEQEEKMQEQEKMRR---------------------------QEEKIREQEEKIREQ 583
K G E K Q E M Q E + EE R +
Sbjct: 484 RKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRR 543
Query: 584 KEKIREQEEKIWE-QEEKIREQEEMMQEQEE--KMWEQEEKMCEQEE---KMQEQEEKMR 637
E E+ EK+ + Q+E E EE+ +++EE K+ E+EE+ +QEE K++E+EEK R
Sbjct: 544 GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEK-R 602
Query: 638 RQEEKMWEQEVRLRQQEEKMQE 659
R +E++ + ++ +KM E
Sbjct: 603 RLKEEIERRRAEAAEKRQKMPE 624
Score = 140 bits (354), Expect = 3e-33
Identities = 109/431 (25%), Positives = 227/431 (52%), Gaps = 24/431 (5%)
Query: 245 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE---ENELWNRLNQQQEEK 301
+ L++K E L Q++ A + + ++ + QVE E RL +++E
Sbjct: 48 ERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREE-- 105
Query: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM--MW 359
R+++++QE E+ +E + I + + + + E EKEEK ++E +
Sbjct: 106 --RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIE 163
Query: 360 EKEEKMRRLEEMMW-EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR---QEQE 415
E E + ++ W + EE +E +EK E+E+ ++ + + ++ +EK QE+
Sbjct: 164 ETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEET 223
Query: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475
M + +I +E K QE++ + ++I EK+ EE+K + + E R E + RE+
Sbjct: 224 VVMSLKNGQISSEEPK---QEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERI 280
Query: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE-EKIREQEEKMWRQEEKIREQEEKIRE 534
+ + K+ E+ +I +E+ ++ E+ +E E++RE+E++ + ++I+E+E++ E
Sbjct: 281 KAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAE 340
Query: 535 QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI 594
+ ++I+E+E+ E+ +++ E+E++ E+ + R EE E++ K+ EQK + +E+K
Sbjct: 341 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE---EEKAKVEEQKRNKQLEEKKH 397
Query: 595 WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654
QE KI+ E ++++ E W E+K QE+K+Q K + +E+ Q R + QE
Sbjct: 398 AMQETKIK--GEKVEQKIEGKWVNEKK--AQEDKLQTAVLKKQGEEKGTKVQAKREKLQE 453
Query: 655 EKMQEHQEHLE 665
+K +E ++
Sbjct: 454 DKPTFKKEEIK 464
Score = 136 bits (343), Expect = 5e-32
Identities = 131/571 (22%), Positives = 280/571 (49%), Gaps = 62/571 (10%)
Query: 53 KETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPEDEQK 112
+E RQ +L EA E+ + +P++ A+ +++ N T TT ++++
Sbjct: 104 EERRQKRLQEALER----QKEFDPTITDASLSLPSRRMQNDTAENETT--------EKEE 151
Query: 113 ASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWK 172
S QE R E+E +TE Y + + RD + +
Sbjct: 152 KSESRQE--RYEIE------------ETETVTKSYQ--------KNDWRDAEENKKEDKE 189
Query: 173 FAGELEQALSAVATQKKKADRYIEELTKE--RDALSLELYRNTITDEELKEKNAKLQEKL 230
E E+ + + + + +EE T E + + + L I+ EE K++ + Q
Sbjct: 190 KEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSD 249
Query: 231 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQ-LQAEADH-LGKELQSVSAKLQAQVEEN 288
++ EK E + + + + ERA+L +++ ++AE D + E + A+ +A +E
Sbjct: 250 EISHHEKMEEE---DKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQER 306
Query: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
E R ++ E+M +E++ E ++I+E+E++ E+ ++I+E+E++ + + + E+E
Sbjct: 307 E---RREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEE 363
Query: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEK--EEKIRELEEKMHEQEKIREQEEKRQEEEKIR 406
++ + + +EE+ ++EE K EEK ++E + EK+ ++ E + EK
Sbjct: 364 KRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKA 423
Query: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 466
+++K Q K +E+ + Q ++ + QE K ++E+I + EKI+++++ +E+ + +
Sbjct: 424 QEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKD-EKIKKDKEPKEEVKSFM 482
Query: 467 QEEK----IREQEEIWRQKEKMHEQEKIRKQ--EEKVWRQEEKMHDQEEKIREQEEKMWR 520
+K ++ Q + + H + + V +E + Q E + EE R
Sbjct: 483 DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRR 542
Query: 521 QEEKIREQEEKIRE-QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579
+ E E+ EK+++ Q+E E EE+ +++EE+ K+ E+E+ RR++E E + K
Sbjct: 543 RGETESEEFEKLKQKQQEAALELEELKKKREER-----RKVLEEEEQRRKQE---EADRK 594
Query: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQE 610
+RE++EK R +EE + E ++++M ++
Sbjct: 595 LREEEEKRRLKEEIERRRAEAAEKRQKMPED 625
Score = 136 bits (342), Expect = 7e-32
Identities = 95/415 (22%), Positives = 210/415 (50%), Gaps = 51/415 (12%)
Query: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
+++ E L +Q+ E+M + E+I ++ ++EE RE+ + R++ + +++EE +
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIA-YQRNDDDEEEAARERRRRARQERLRQKQEEESL 59
Query: 345 WE--------------KEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE 390
+ EE E +++ LE + +E + + L+E + Q+
Sbjct: 60 GQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQK 119
Query: 391 KIREQ--------EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 442
+ +R + + + +E++++ ++ +I E E + +K WR
Sbjct: 120 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRD 179
Query: 443 EEKIHEQEKIREEEKRQE---------QEEMWRQEEKIREQEE--IWRQKEKMHEQEKIR 491
E+ +++K +EEE+ ++ Q E+ +E+ QEE + K E+ +
Sbjct: 180 AEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPK 239
Query: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR---EQEEKIREQEEKIREQEEMMQE 548
++EE+ +E H ++ E+E+K + E+ R E+ E+I+ +++K E E
Sbjct: 240 QEEEREQGSDEISHHEK---MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIE 296
Query: 549 QEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMM 608
EEK QE + +E E + E++RE+E++ E++++I+E+E++ E+ ++I+E+E+
Sbjct: 297 AEEKAAAQERERREAE----ERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRA 352
Query: 609 QEQEEKMWEQEEKMCEQEEKMQ-EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
E+ +++ E+E++ E+ ++ + E+EEK + +E+K R +Q EEK QE
Sbjct: 353 AEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQK------RNKQLEEKKHAMQE 401
Score = 133 bits (334), Expect = 6e-31
Identities = 117/461 (25%), Positives = 235/461 (50%), Gaps = 55/461 (11%)
Query: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQA--EADHLGKEL 274
E +E + +E+++L E+E+ Q N + + + Q++L+ E + LG+
Sbjct: 5 ERRRELRRQKREEMRL-EAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVT 63
Query: 275 QSVSAKLQAQVEENEL-WNRLNQQQE--------EKMWRQEEKIQEWEEKIQEQEEKIRE 325
V Q V + E N Q E E++ R+EE+ Q+ ++QE E+ +E
Sbjct: 64 DQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQK---RLQEALERQKE 120
Query: 326 QEEKIREQEEKM--RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE 383
+ I + + RR + E E EKEEK +E +E EE E
Sbjct: 121 FDPTITDASLSLPSRRMQNDTAENETT---------EKEEKSESRQER-YEIEET--ETV 168
Query: 384 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK--MWR 441
K +++ R+ EE ++E+++ E+E+ + + + + ++ +E+ QE+ M
Sbjct: 169 TKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSL 228
Query: 442 QEEKIHEQEKIREEEKRQEQEEMW---RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498
+ +I +E +EEE+ Q +E+ + EE+ +E+ E R + + E+E+I+ +++K
Sbjct: 229 KNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKI 288
Query: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558
E + EEK QE +E + E+ E++RE+E++ E+ + ++E+E++ E+ +
Sbjct: 289 ADERARIEAEEKAAAQE-----RERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQ 343
Query: 559 KMQEQEKMRRQE-EKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE 617
+++E+EK +E ++I+E+E++ E++++ R +EE EK + +E+ +Q E
Sbjct: 344 RIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE------EKAKVEEQKRNKQLE---- 393
Query: 618 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
E+K QE K+ + EK+ ++ E W E + QE+K+Q
Sbjct: 394 -EKKHAMQETKI--KGEKVEQKIEGKWVNE--KKAQEDKLQ 429
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 148 bits (374), Expect = 1e-35
Identities = 99/391 (25%), Positives = 201/391 (51%), Gaps = 24/391 (6%)
Query: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE---------QEEKIREQEEKMRRQEE 342
NR +++ + RQ E+ E + K + + EK R Q ++ +E+E + R+ +
Sbjct: 57 NRQKERERRREKRQTER--ETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE-EKIRELEEKMHEQEKIREQEEKRQE 401
EKE +++ E E+E + R + ++E E+ R+ E++ Q Q + +
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EEKRQE 460
+K RE+EK +++ + RQ EK + E++ E+ ++ R+ E E E+ R+ + +R
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 461 QEEMWRQEEKIREQE---------EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKI 511
Q + R+ EK E+E + R++E+ ++++ R+Q+E+ + + K + E+
Sbjct: 235 QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
Query: 512 REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEE 571
RE E K RQ E+ RE+E + + E+ RE+E Q + E+ E+E + + + + E
Sbjct: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
Query: 572 KIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 631
+ R+ + R Q E+ RE+E + + RE+EE ++++ ++ E+ E++ Q
Sbjct: 355 RNRQTGREGRRQAERERERERE--RDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
Query: 632 QEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
+ EK R +E+ + R R +E + Q+ +E
Sbjct: 413 ETEKQREREKDRESERGRERGREREKQKGRE 443
Score = 143 bits (361), Expect = 4e-34
Identities = 97/358 (27%), Positives = 197/358 (55%), Gaps = 13/358 (3%)
Query: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
E Q++ E+ RE+ + RE + K R+ E ++ R+ + EKE + + E
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE-QEEK 431
++E++ +E+ E E+ E+ RQ + + RE+E++++ E + RQ ++ R+ Q E+
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQ-RERERQRDAEKERERQTDRERQRQTER 173
Query: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE---EIWRQKEKMHEQE 488
R++E++ + ++ E+E+ RE+E + E R E+ RE+E E R+++ E++
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 489 KIRKQEEKVWRQEEKMHDQE---EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
+ RK E + +Q E+ E E+ +E+E + R ++ R Q+E+ R+ + K + + E
Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 546 MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQE 605
+E E K Q E+ +E+E+ R++E + RE+E + Q+E R++E+ E+E K + Q
Sbjct: 294 DRETERKRERQRERERERERNRKRERE-RERERERERQRETERDREK---ERERKRKRQT 349
Query: 606 EMMQEQEEKMWEQEEKMCEQE-EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
EM +E+ + + + E+E E+ +E++ + R+ E+ R RQ+E + Q ++
Sbjct: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Score = 136 bits (342), Expect = 7e-32
Identities = 105/410 (25%), Positives = 209/410 (50%), Gaps = 24/410 (5%)
Query: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
E +EK +E + E + + + ++ R+ +R + ++Q E D ++ ++
Sbjct: 63 ERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERN 122
Query: 277 VSAKLQAQVEENELWNRLNQ---QQEEKMWRQEEKIQEWEEKIQEQEEKIRE-QEEKIRE 332
+ + + E R Q Q+E + R EK +E + + Q + R Q+E+ RE
Sbjct: 123 RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERERE 182
Query: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392
+ + RR+ E EKE K + + E+ R E + E+ R+ + + Q K
Sbjct: 183 KNRQERRERERQREKENKTEDRHSERGRERERERETET----ETERKRQTDRERDRQRKT 238
Query: 393 REQEEKRQEEEKI--REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 450
+ EK+ E E+ RE E+ +E+E + R ++ R Q+E+ R+ ++K R+ E+ E E
Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
Query: 451 KIREEEKRQEQE-EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEE 509
+ RE ++ +E+E E R+ E+ RE+E R++E+ E E+ R++E + R+ + D+E
Sbjct: 299 RKRERQRERERERERNRKRERERERE---RERERQRETERDREKERERKRKRQTEMDRER 355
Query: 510 KIREQEEKMWRQEEKIREQE-----EKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
R+ + RQ E+ RE+E + RE+EE+ R+++ Q++ E+ E++ Q +
Sbjct: 356 N-RQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET 414
Query: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
+ +R+ EK RE E +E+ RE+E++ + ++ R+ + Q ++
Sbjct: 415 EKQREREKDRESE----RGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 135 bits (339), Expect = 2e-31
Identities = 100/426 (23%), Positives = 226/426 (53%), Gaps = 25/426 (5%)
Query: 187 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE 246
++K+ +R E+ ER+ + R +++ K + +E+ + E E+ ++
Sbjct: 58 RQKERERRREKRQTERET---DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE--ENELWNRLNQQQEEKMWR 304
+R+ ER + +++ + E + G++ Q+ + + + E E + +++++ + R
Sbjct: 115 RQREKERNRQKERERETEREGER-GRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
Query: 305 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
+K +E E+ QE+ E+ R++E++ + ++ R E E+E + + + ++E
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 365 MRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 424
+R E EK+ + E+ E++K RE+E R + R++E+ ++ + K R+ E+
Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 425 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKM 484
RE E +K RQ E+ E+E+ R+ E+ +E+E R+ E+ RE E R +EK
Sbjct: 294 DRETE-------RKRERQRERERERERNRKRERERERE---RERERQRETE---RDREK- 339
Query: 485 HEQEKIRKQEEKVWRQEEKMHDQE---EKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541
E+E+ RK++ ++ R+ + +E + RE+E + R + RE+EE+ R++ ++ R+
Sbjct: 340 -ERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR-DRDRQ 397
Query: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI 601
+E Q ++++ G++E + Q + + R+ E+ RE+ + +QK + R++E + Q +
Sbjct: 398 KERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457
Query: 602 REQEEM 607
R++ +
Sbjct: 458 RKRSTL 463
Score = 134 bits (336), Expect = 4e-31
Identities = 96/326 (29%), Positives = 183/326 (56%), Gaps = 17/326 (5%)
Query: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH-EQEKIREQEEKRQEEEK 404
++E +++ E EK + R + + EK R + H E+++ RE+E +RQ +
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTD-- 110
Query: 405 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK---RQEQ 461
RE+++++E+E RQ+E+ RE E RE E+ RQ + E+E+ R+ EK RQ
Sbjct: 111 -RERDRQREKERN--RQKERERETE---REGERGRDRQTDGQRERERQRDAEKERERQTD 164
Query: 462 EEMWRQEEKIREQE-EIWRQKEKMHEQEKIRKQEEKVW-RQEEKMHDQE-EKIREQEEKM 518
E RQ E+ R++E E + +++ E+E+ R++E K R E+ ++E E+ E E +
Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETER 224
Query: 519 WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQE-EKMQEQEKMRRQEEKIREQE 577
RQ ++ R+++ K + EK E+E + + E+ E+E E+ +++++ RRQ+E+ R+ +
Sbjct: 225 KRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTD 284
Query: 578 EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE-EKMCEQEEKMQEQEEKM 636
K + + E+ RE E K Q E+ RE+E + + E+ E+E E+ E E +++ E+
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344
Query: 637 RRQEEKMWEQEVRLRQQEEKMQEHQE 662
R+++ +M + R +E + Q +E
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERE 370
Score = 109 bits (273), Expect = 7e-24
Identities = 70/282 (24%), Positives = 151/282 (53%), Gaps = 26/282 (9%)
Query: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453
+ E+ +++E+ R +EKRQ + R+ ++ RE R +EK R+ ++ E+++ R
Sbjct: 52 DDRERNRQKERERRREKRQTE-----RETDRKRE-----RRREKDRHRKRDRHRERQRDR 101
Query: 454 EEEKRQEQEEMWRQEEKIREQE---EIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD---- 506
E+E+ ++ + R+ ++ RE+E + R++E E E+ R ++ R+ E+ D
Sbjct: 102 EKERERQTD---RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKE 158
Query: 507 ---QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
Q ++ R+++ + RQ+E+ RE+ + R + E+ RE+E +++ + G + E+ +E
Sbjct: 159 RERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERET 218
Query: 564 E---KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
E + +RQ ++ R+++ K ++EK E+E + E+ +E+E ++ Q+E
Sbjct: 219 ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE 278
Query: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
+ + + K Q + E+ R E K Q R R++E + +E
Sbjct: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
Score = 107 bits (268), Expect = 3e-23
Identities = 64/276 (23%), Positives = 150/276 (54%), Gaps = 10/276 (3%)
Query: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR 453
++ +R+ + + ++E ++ E+ RE+ + RE ++K R+ EK +++ R
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
Query: 454 EEEKRQEQE-EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD---QEE 509
E+++++E E RQ ++ R+++ R+KE+ ++E+ R+ E + R ++ D + E
Sbjct: 94 HRERQRDREKERERQTDRERDRQ---REKERNRQKERERETEREGERGRDRQTDGQRERE 150
Query: 510 KIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR-- 567
+ R+ E++ RQ ++ R+++ + Q+E+ RE+ + + E+ E+E K +++ R
Sbjct: 151 RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGR 210
Query: 568 -RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 626
R+ E+ E E + + Q ++ R+++ K + EK E+E + + E+ E+E +
Sbjct: 211 ERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDR 270
Query: 627 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
++ + Q+E+ R+ + K + R R+ E K + +E
Sbjct: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306
Score = 94.0 bits (232), Expect = 4e-19
Identities = 96/417 (23%), Positives = 196/417 (47%), Gaps = 34/417 (8%)
Query: 84 DTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALR-RELEAQVHTIRILTCQKTEL 142
+ ++++ T ET +D + +H+E R RE E + T R Q+ E
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR-EK 119
Query: 143 QMALYYSQHAVKQLEGE-ARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKE 201
+ + + EGE RD R D + E E+ A ++++ DR + T+
Sbjct: 120 ERNRQKERERETEREGERGRD---RQTDGQR---ERERQRDAEKERERQTDRERQRQTER 173
Query: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261
E +N E +E+ + + K + SE+ + +E + + ER + ++
Sbjct: 174 NRQKEREREKNRQERRE-RERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEE 321
Q + + ++ + + E ++ R + ++ RQ+E+ ++ + K Q + E
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 322 KIRE-------QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374
+ RE Q E+ RE+E +R+ E E+E + +R+ E EKE + +R + +
Sbjct: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
Query: 375 KE-------EKIRELE-EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 426
+E E R+ E E+ E+E+ R+ +R+E E+ R++++++E+E RQ EK R
Sbjct: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE----RQTEKDR 408
Query: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
+ + RE EK+ R+ EK E E+ RE + +E+++ ++ + + + RQ+++
Sbjct: 409 DGQ---RETEKQ--REREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 75.5 bits (184), Expect = 1e-13
Identities = 46/189 (24%), Positives = 103/189 (54%), Gaps = 9/189 (4%)
Query: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
RQKE+ +EK R+ E + R+ E+ ++++ R+++ RQ ++ +E+E + + ++
Sbjct: 58 RQKERERRREK-RQTERETDRKRERRR-EKDRHRKRDRHRERQRDREKERERQTDRERDR 115
Query: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
RE+E Q++ E+ E+E + + Q E+ R+++ + +++ RE++ +
Sbjct: 116 QREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNR 175
Query: 599 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ--EEKMRRQEEKMWEQEVRLRQQEEK 656
+K RE+E+ QE+ E+ E+ E+E K +++ E R+ E+ E E ++Q ++
Sbjct: 176 QKEREREKNRQERRER-----ERQREKENKTEDRHSERGRERERERETETETERKRQTDR 230
Query: 657 MQEHQEHLE 665
++ Q E
Sbjct: 231 ERDRQRKTE 239
Score = 34.7 bits (78), Expect = 0.29
Identities = 20/103 (19%), Positives = 50/103 (48%)
Query: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE 613
G QE + ++ ++E ++++E+ RE+ + E + K + E + ++
Sbjct: 32 GSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKR 91
Query: 614 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656
+ ++ E+E + Q E+ R++E++ Q+ R R+ E +
Sbjct: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETERE 134
>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 148 bits (374), Expect = 1e-35
Identities = 131/501 (26%), Positives = 234/501 (46%), Gaps = 112/501 (22%)
Query: 51 MSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPED- 109
M++ET+ +KLA AK++L ++ + P V + +K NG+ PET TSGGC P D
Sbjct: 1 MAEETQHNKLAAAKKKLKEYWQKNRPRVPAGVNRNRK---TNGSIPETATSGGCQPPGDS 57
Query: 110 -----------------------------------------------EQKASHQHQ---- 118
+QK +HQ
Sbjct: 58 ATGFHREGPTSSATLKDLESPCQERAVVLDSTSVKISRLKNTIKSLKQQKKQVEHQLEEE 117
Query: 119 -------EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSW 171
+ RELE Q+ T+ I QK EL LY+ + +++ E E++DL RL S
Sbjct: 118 KKANNERQKAERELEVQIQTLII---QKEELNTDLYHMERSLRYFEEESKDLAVRLQHSL 174
Query: 172 KFAGELEQALSAV-ATQKKKADRY-----------IEELTKERDALSLELYRNTITDEEL 219
+ GELE ALSAV AT+KKKA++ +E+ +++ L +L + + ++L
Sbjct: 175 QCKGELESALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQL 234
Query: 220 K------------------EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL--- 258
+ ++ +K+ +++ ++ EK + V+EL+R L + K +
Sbjct: 235 QLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEP 294
Query: 259 -----PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
P + E HL KEL+ V+ +LQ+QV+ N+ + LN++QEE++ QEE++++ E
Sbjct: 295 LPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQE 354
Query: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
E++QEQ EK+R Q K + E++ + + + E++++ +E + E+ + +
Sbjct: 355 ERLQEQHEKLR-QLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQNQQL 413
Query: 374 EKEEKIRELEEKMHEQEKI-REQEEKRQEEEKIREQ-EKRQEQEAKMWRQEEKIREQEEK 431
+ + L + H E + E EE Q + E E R+ + M +EK + E
Sbjct: 414 TAQLSLMALPGEGHGGEHLDSEGEEAPQPMPSVPEDLESREAMSSFMDHLKEK-ADLSEL 472
Query: 432 IREQEKKM---WRQ--EEKIH 447
+++QE + W++ +KIH
Sbjct: 473 VKKQELRFIQYWQERCHQKIH 493
Score = 88.6 bits (218), Expect = 2e-17
Identities = 76/330 (23%), Positives = 162/330 (49%), Gaps = 41/330 (12%)
Query: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWR 420
K+ RL+ + +++ +++E ++ E++K + +K + E +++ Q +++E ++
Sbjct: 92 KISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLYH 151
Query: 421 QEEKIREQEEK-----IREQEKKMWRQEEKIHEQEKIREEEKRQEQ-------EEMWRQE 468
E +R EE+ +R Q + E + I E+K+ Q W E
Sbjct: 152 MERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWELE 211
Query: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI--- 525
+ +++Q + Q ++ E Q+ ++ R E H + E+ R ++M + ++I
Sbjct: 212 QSLQDQALLKAQLTQLKESF----QQLQLERDECAEHIEGERAR-WHQRMSKMSQEICTL 266
Query: 526 -REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQ---EQEKMRRQEEKIREQEEKIR 581
+E+++ +R EE R ++ + E + + + E + +R++ E++ + +
Sbjct: 267 KKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQV 326
Query: 582 EQKEKI----REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637
+ + I R QEE+I EQEE++R+QEE +QEQ EK+ Q K Q E++
Sbjct: 327 KNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL--------RQLAKPQSVFEELN 378
Query: 638 RQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
+ + + E ++++ +EK+ E EHLEAA
Sbjct: 379 NENKSTLQLEQQVKELQEKLGE--EHLEAA 406
Score = 81.6 bits (200), Expect = 2e-15
Identities = 68/331 (20%), Positives = 155/331 (46%), Gaps = 42/331 (12%)
Query: 315 KIQEQEEKIREQEEKIREQ--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
+++ + +++Q++++ Q EEK E E+E +++ Q ++ +KEE L +
Sbjct: 95 RLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQT-LIIQKEE----LNTDL 149
Query: 373 WEKEEKIRELEEKMHE-----QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 427
+ E +R EE+ + Q ++ + E + EK++ + + E
Sbjct: 150 YHMERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWE 209
Query: 428 QEEKIREQ---EKKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQKE 482
E+ +++Q + ++ + +E + + R+E E + + W Q QE +KE
Sbjct: 210 LEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKE 269
Query: 483 KMHEQEKIRKQEEKVWRQEEKMHD--------------------QEEKIREQEEKMWRQE 522
K + ++ + E + + + +M + + E++ + + +
Sbjct: 270 KQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNN 329
Query: 523 EKI----REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578
+ I R QEE+IREQEE++R+QEE +QEQ EK+ + + E++ + + + E+
Sbjct: 330 QHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQ 389
Query: 579 KIREQKEKIREQE-EKIWEQEEKIREQEEMM 608
+++E +EK+ E+ E +Q +++ Q +M
Sbjct: 390 QVKELQEKLGEEHLEAASQQNQQLTAQLSLM 420
>gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 2 [Homo sapiens]
Length = 595
Score = 148 bits (373), Expect = 2e-35
Identities = 124/447 (27%), Positives = 218/447 (48%), Gaps = 108/447 (24%)
Query: 51 MSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCH----- 105
M++ET+ +KLA AK++L ++ + P V + +K NG+ PET TSGGCH
Sbjct: 1 MAEETQHNKLAAAKKKLKEYWQKNRPRVPAGVNRNRK---TNGSIPETATSGGCHLSPHS 57
Query: 106 -----------SP------------------------------------EDEQKASHQHQ 118
SP E+E+KA+++ Q
Sbjct: 58 CSTSSSLHAPQSPCQERAVVLDSTSVKISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQ 117
Query: 119 EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELE 178
+A RELE Q+ T+ I QK EL LY+ + +++ E E++DL RL S + GELE
Sbjct: 118 KA-ERELEVQIQTLII---QKEELNTDLYHMERSLRYFEEESKDLAVRLQHSLQCKGELE 173
Query: 179 QALSAV-ATQKKKADRY-----------IEELTKERDALSLELYRNTITDEELK------ 220
ALSAV AT+KKKA++ +E+ +++ L +L + + ++L+
Sbjct: 174 SALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERDEC 233
Query: 221 ------------EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL--------PQ 260
++ +K+ +++ ++ EK + V+EL+R L + K + P
Sbjct: 234 AEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPA 293
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
+ E HL KEL+ V+ +LQ+QV+ N+ + LN++QEE++ QEE++++ EE++QEQ
Sbjct: 294 VPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQH 353
Query: 321 EKIREQE------EKIREQEEKMRRQEEMMWEKEEKMR--RQEEMMWEKEEKMRR---LE 369
EK+R+ E++ + + + E+ + E +EK+ ++ E +KE + R
Sbjct: 354 EKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKETETSAQKEPEAARGPGAP 413
Query: 370 EMMWEKEEKIRELEEKMHEQEKIREQE 396
E + L+EK E +++QE
Sbjct: 414 GPGGESSSFMDHLKEKADLSELVKKQE 440
Score = 83.6 bits (205), Expect = 5e-16
Identities = 70/313 (22%), Positives = 152/313 (48%), Gaps = 43/313 (13%)
Query: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWR 420
K+ RL+ + +++ +++E ++ E++K + +K + E +++ Q +++E ++
Sbjct: 84 KISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLYH 143
Query: 421 QEEKIREQEEK-----IREQEKKMWRQEEKIHEQEKIREEEKRQEQ-------EEMWRQE 468
E +R EE+ +R Q + E + I E+K+ Q W E
Sbjct: 144 MERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWELE 203
Query: 469 EKIREQEEIWRQKEKMHE---QEKIRKQE--EKVWRQEEKMHDQEEKI--------REQE 515
+ +++Q + Q ++ E Q ++ + E E + + + H + K+ +E++
Sbjct: 204 QSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQ 263
Query: 516 EKMWRQEEKIREQEEKIREQEEKIR----------EQEEMMQEQEEKMGEQEEKMQEQEK 565
+ M R EE R + + E + E + + +E E GE + +++ +
Sbjct: 264 QDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQH 323
Query: 566 M----RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
+ RRQEE+IREQEE++R+Q+E+++EQ EK+ Q K + E + + + + E++
Sbjct: 324 ISLLNRRQEERIREQEERLRKQEERLQEQHEKL-RQLAKPQSVFEELNNENKSTLQLEQQ 382
Query: 622 MCEQEEKMQEQEE 634
+ E +EK+ E +E
Sbjct: 383 VKELQEKLGEVKE 395
Score = 82.8 bits (203), Expect = 9e-16
Identities = 68/321 (21%), Positives = 152/321 (47%), Gaps = 25/321 (7%)
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI----QEWEEKIQEQEEKIREQE 327
K L+ +++ Q+EE + N Q+ E ++ Q + + +E + E +R E
Sbjct: 93 KSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLYHMERSLRYFE 152
Query: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
E+ ++ +++ + E E + ++ +++K +L K ELE+ +
Sbjct: 153 EESKDLAVRLQHSLQCKGELESAL---SAVIATEKKKANQLSSC--SKAHTEWELEQSLQ 207
Query: 388 EQEKIREQEEKRQE---EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
+Q ++ Q + +E + ++ E + E + R +++ + ++I +K+ +
Sbjct: 208 DQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMR 267
Query: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
++ E E+ + K Q E + + + + E+ + +RK+ E+V + +
Sbjct: 268 RVEELERSLSKLKNQMAEPLPPEPPAVPSEVEL----------QHLRKELERVAGELQSQ 317
Query: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
+ I RQEE+IREQEE++R+QEE+++EQ E +++ + EE E +
Sbjct: 318 VKNNQHISLLNR---RQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENK 374
Query: 565 KMRRQEEKIREQEEKIREQKE 585
+ E++++E +EK+ E KE
Sbjct: 375 STLQLEQQVKELQEKLGEVKE 395
Score = 79.7 bits (195), Expect = 8e-15
Identities = 65/314 (20%), Positives = 147/314 (46%), Gaps = 41/314 (13%)
Query: 315 KIQEQEEKIREQEEKIREQ--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
+++ + +++Q++++ Q EEK E E+E +++ Q ++ +KEE L +
Sbjct: 87 RLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQT-LIIQKEE----LNTDL 141
Query: 373 WEKEEKIRELEEKMHE-----QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 427
+ E +R EE+ + Q ++ + E + EK++ + + E
Sbjct: 142 YHMERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWE 201
Query: 428 QEEKIREQ---EKKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQKE 482
E+ +++Q + ++ + +E + + R+E E + + W Q QE +KE
Sbjct: 202 LEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKE 261
Query: 483 KMHEQEKIRKQEEKVWRQEEKMHD--------------------QEEKIREQEEKMWRQE 522
K + ++ + E + + + +M + + E++ + + +
Sbjct: 262 KQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNN 321
Query: 523 EKI----REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578
+ I R QEE+IREQEE++R+QEE +QEQ EK+ + + E++ + + + E+
Sbjct: 322 QHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQ 381
Query: 579 KIREQKEKIREQEE 592
+++E +EK+ E +E
Sbjct: 382 QVKELQEKLGEVKE 395
Score = 67.8 bits (164), Expect = 3e-11
Identities = 68/289 (23%), Positives = 132/289 (45%), Gaps = 18/289 (6%)
Query: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 437
KI L+ + ++ ++Q E + EEEK + +RQ+ E ++ Q + + Q+E++
Sbjct: 84 KISRLKNTIKSLKQQKKQVEHQLEEEK-KANNERQKAERELEVQIQTLIIQKEELNTDLY 142
Query: 438 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKV 497
M R E+ K + R + + E + I +K+K ++ K +
Sbjct: 143 HMERSLRYFEEESK--DLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTE- 199
Query: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE--QEEKIREQEEMMQEQEEKMGE 555
W E+ + DQ ++ Q ++ ++++ + ++ E + E+ R + M + +E
Sbjct: 200 WELEQSLQDQA-LLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTL 258
Query: 556 QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM 615
++EK Q+ MRR EE + K++ Q + E E +Q +++
Sbjct: 259 KKEKQQD---MRRVEE--------LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKEL 307
Query: 616 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
++ Q + Q RRQEE++ EQE RLR+QEE++QE E L
Sbjct: 308 ERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL 356
Score = 58.2 bits (139), Expect = 2e-08
Identities = 66/338 (19%), Positives = 139/338 (41%), Gaps = 93/338 (27%)
Query: 408 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE----- 462
Q QE+ + KI + I+ +++ + E ++ E++K E ++ E+E
Sbjct: 68 QSPCQERAVVLDSTSVKISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQI 127
Query: 463 ------------EMWRQEEKIREQEE--------------------------IWRQKEKM 484
+++ E +R EE I +K+K
Sbjct: 128 QTLIIQKEELNTDLYHMERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKA 187
Query: 485 HEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE--QEEKIREQ 542
++ K + W E+ + DQ ++ Q ++ ++++ + ++ E + E+ R
Sbjct: 188 NQLSSCSKAHTE-WELEQSLQDQ-ALLKAQLTQLKESFQQLQLERDECAEHIEGERARWH 245
Query: 543 EEMMQEQEEKMGEQEEKMQEQ---EKMRRQEEKIREQE-----------------EKIRE 582
+ M + +E ++EK Q+ E++ R K++ Q + +R+
Sbjct: 246 QRMSKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRK 305
Query: 583 QKEKI------------------REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624
+ E++ R QEE+I EQEE++R+QEE +QEQ EK+
Sbjct: 306 ELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL--------R 357
Query: 625 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Q K Q E++ + + + E ++++ +EK+ E +E
Sbjct: 358 QLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKE 395
>gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 2 [Homo sapiens]
Length = 595
Score = 148 bits (373), Expect = 2e-35
Identities = 124/447 (27%), Positives = 218/447 (48%), Gaps = 108/447 (24%)
Query: 51 MSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCH----- 105
M++ET+ +KLA AK++L ++ + P V + +K NG+ PET TSGGCH
Sbjct: 1 MAEETQHNKLAAAKKKLKEYWQKNRPRVPAGVNRNRK---TNGSIPETATSGGCHLSPHS 57
Query: 106 -----------SP------------------------------------EDEQKASHQHQ 118
SP E+E+KA+++ Q
Sbjct: 58 CSTSSSLHAPQSPCQERAVVLDSTSVKISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQ 117
Query: 119 EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELE 178
+A RELE Q+ T+ I QK EL LY+ + +++ E E++DL RL S + GELE
Sbjct: 118 KA-ERELEVQIQTLII---QKEELNTDLYHMERSLRYFEEESKDLAVRLQHSLQCKGELE 173
Query: 179 QALSAV-ATQKKKADRY-----------IEELTKERDALSLELYRNTITDEELK------ 220
ALSAV AT+KKKA++ +E+ +++ L +L + + ++L+
Sbjct: 174 SALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERDEC 233
Query: 221 ------------EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL--------PQ 260
++ +K+ +++ ++ EK + V+EL+R L + K + P
Sbjct: 234 AEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPA 293
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
+ E HL KEL+ V+ +LQ+QV+ N+ + LN++QEE++ QEE++++ EE++QEQ
Sbjct: 294 VPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQH 353
Query: 321 EKIREQE------EKIREQEEKMRRQEEMMWEKEEKMR--RQEEMMWEKEEKMRR---LE 369
EK+R+ E++ + + + E+ + E +EK+ ++ E +KE + R
Sbjct: 354 EKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKETETSAQKEPEAARGPGAP 413
Query: 370 EMMWEKEEKIRELEEKMHEQEKIREQE 396
E + L+EK E +++QE
Sbjct: 414 GPGGESSSFMDHLKEKADLSELVKKQE 440
Score = 83.6 bits (205), Expect = 5e-16
Identities = 70/313 (22%), Positives = 152/313 (48%), Gaps = 43/313 (13%)
Query: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWR 420
K+ RL+ + +++ +++E ++ E++K + +K + E +++ Q +++E ++
Sbjct: 84 KISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLYH 143
Query: 421 QEEKIREQEEK-----IREQEKKMWRQEEKIHEQEKIREEEKRQEQ-------EEMWRQE 468
E +R EE+ +R Q + E + I E+K+ Q W E
Sbjct: 144 MERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWELE 203
Query: 469 EKIREQEEIWRQKEKMHE---QEKIRKQE--EKVWRQEEKMHDQEEKI--------REQE 515
+ +++Q + Q ++ E Q ++ + E E + + + H + K+ +E++
Sbjct: 204 QSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQ 263
Query: 516 EKMWRQEEKIREQEEKIREQEEKIR----------EQEEMMQEQEEKMGEQEEKMQEQEK 565
+ M R EE R + + E + E + + +E E GE + +++ +
Sbjct: 264 QDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQH 323
Query: 566 M----RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
+ RRQEE+IREQEE++R+Q+E+++EQ EK+ Q K + E + + + + E++
Sbjct: 324 ISLLNRRQEERIREQEERLRKQEERLQEQHEKL-RQLAKPQSVFEELNNENKSTLQLEQQ 382
Query: 622 MCEQEEKMQEQEE 634
+ E +EK+ E +E
Sbjct: 383 VKELQEKLGEVKE 395
Score = 82.8 bits (203), Expect = 9e-16
Identities = 68/321 (21%), Positives = 152/321 (47%), Gaps = 25/321 (7%)
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI----QEWEEKIQEQEEKIREQE 327
K L+ +++ Q+EE + N Q+ E ++ Q + + +E + E +R E
Sbjct: 93 KSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLYHMERSLRYFE 152
Query: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
E+ ++ +++ + E E + ++ +++K +L K ELE+ +
Sbjct: 153 EESKDLAVRLQHSLQCKGELESAL---SAVIATEKKKANQLSSC--SKAHTEWELEQSLQ 207
Query: 388 EQEKIREQEEKRQE---EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
+Q ++ Q + +E + ++ E + E + R +++ + ++I +K+ +
Sbjct: 208 DQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMR 267
Query: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
++ E E+ + K Q E + + + + E+ + +RK+ E+V + +
Sbjct: 268 RVEELERSLSKLKNQMAEPLPPEPPAVPSEVEL----------QHLRKELERVAGELQSQ 317
Query: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
+ I RQEE+IREQEE++R+QEE+++EQ E +++ + EE E +
Sbjct: 318 VKNNQHISLLNR---RQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENK 374
Query: 565 KMRRQEEKIREQEEKIREQKE 585
+ E++++E +EK+ E KE
Sbjct: 375 STLQLEQQVKELQEKLGEVKE 395
Score = 79.7 bits (195), Expect = 8e-15
Identities = 65/314 (20%), Positives = 147/314 (46%), Gaps = 41/314 (13%)
Query: 315 KIQEQEEKIREQEEKIREQ--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
+++ + +++Q++++ Q EEK E E+E +++ Q ++ +KEE L +
Sbjct: 87 RLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQT-LIIQKEE----LNTDL 141
Query: 373 WEKEEKIRELEEKMHE-----QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 427
+ E +R EE+ + Q ++ + E + EK++ + + E
Sbjct: 142 YHMERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWE 201
Query: 428 QEEKIREQ---EKKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQKE 482
E+ +++Q + ++ + +E + + R+E E + + W Q QE +KE
Sbjct: 202 LEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKE 261
Query: 483 KMHEQEKIRKQEEKVWRQEEKMHD--------------------QEEKIREQEEKMWRQE 522
K + ++ + E + + + +M + + E++ + + +
Sbjct: 262 KQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNN 321
Query: 523 EKI----REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578
+ I R QEE+IREQEE++R+QEE +QEQ EK+ + + E++ + + + E+
Sbjct: 322 QHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQ 381
Query: 579 KIREQKEKIREQEE 592
+++E +EK+ E +E
Sbjct: 382 QVKELQEKLGEVKE 395
Score = 67.8 bits (164), Expect = 3e-11
Identities = 68/289 (23%), Positives = 132/289 (45%), Gaps = 18/289 (6%)
Query: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 437
KI L+ + ++ ++Q E + EEEK + +RQ+ E ++ Q + + Q+E++
Sbjct: 84 KISRLKNTIKSLKQQKKQVEHQLEEEK-KANNERQKAERELEVQIQTLIIQKEELNTDLY 142
Query: 438 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKV 497
M R E+ K + R + + E + I +K+K ++ K +
Sbjct: 143 HMERSLRYFEEESK--DLAVRLQHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTE- 199
Query: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE--QEEKIREQEEMMQEQEEKMGE 555
W E+ + DQ ++ Q ++ ++++ + ++ E + E+ R + M + +E
Sbjct: 200 WELEQSLQDQA-LLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTL 258
Query: 556 QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM 615
++EK Q+ MRR EE + K++ Q + E E +Q +++
Sbjct: 259 KKEKQQD---MRRVEE--------LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKEL 307
Query: 616 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
++ Q + Q RRQEE++ EQE RLR+QEE++QE E L
Sbjct: 308 ERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL 356
Score = 58.2 bits (139), Expect = 2e-08
Identities = 66/338 (19%), Positives = 139/338 (41%), Gaps = 93/338 (27%)
Query: 408 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE----- 462
Q QE+ + KI + I+ +++ + E ++ E++K E ++ E+E
Sbjct: 68 QSPCQERAVVLDSTSVKISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQI 127
Query: 463 ------------EMWRQEEKIREQEE--------------------------IWRQKEKM 484
+++ E +R EE I +K+K
Sbjct: 128 QTLIIQKEELNTDLYHMERSLRYFEEESKDLAVRLQHSLQCKGELESALSAVIATEKKKA 187
Query: 485 HEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE--QEEKIREQ 542
++ K + W E+ + DQ ++ Q ++ ++++ + ++ E + E+ R
Sbjct: 188 NQLSSCSKAHTE-WELEQSLQDQ-ALLKAQLTQLKESFQQLQLERDECAEHIEGERARWH 245
Query: 543 EEMMQEQEEKMGEQEEKMQEQ---EKMRRQEEKIREQE-----------------EKIRE 582
+ M + +E ++EK Q+ E++ R K++ Q + +R+
Sbjct: 246 QRMSKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRK 305
Query: 583 QKEKI------------------REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624
+ E++ R QEE+I EQEE++R+QEE +QEQ EK+
Sbjct: 306 ELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL--------R 357
Query: 625 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Q K Q E++ + + + E ++++ +EK+ E +E
Sbjct: 358 QLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKE 395
>gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 4 [Homo sapiens]
Length = 632
Score = 148 bits (373), Expect = 2e-35
Identities = 131/501 (26%), Positives = 235/501 (46%), Gaps = 112/501 (22%)
Query: 51 MSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCHSPED- 109
M++ET+ +KLA AK++L ++ + P V + +K NG+ PET TSGGC P D
Sbjct: 1 MAEETQHNKLAAAKKKLKEYWQKNRPRVPAGVNRNRK---TNGSIPETATSGGCQPPGDS 57
Query: 110 -----------------------------------------------EQKASHQHQ---- 118
+QK +HQ
Sbjct: 58 ATGFHREGPTSSATLKDLESPCQERAVVLDSTSVKISRLKNTIKSLKQQKKQVEHQLEEE 117
Query: 119 -------EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSW 171
+ RELE Q+ T+ I QK EL LY+ + +++ E E++DL RL S
Sbjct: 118 KKANNERQKAERELEVQIQTLII---QKEELNTDLYHMERSLRYFEEESKDLAVRLQHSL 174
Query: 172 KFAGELEQALSAV-ATQKKKADRY-----------IEELTKERDALSLELYRNTITDEEL 219
+ GELE+ALSAV AT+KKKA++ +E+ +++ L +L + + ++L
Sbjct: 175 QCKGELERALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQL 234
Query: 220 K------------------EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL--- 258
+ ++ +K+ +++ ++ EK + V+EL+R L + K +
Sbjct: 235 QLERDECAEHIEGERARWHQRMSKMLQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEP 294
Query: 259 -----PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313
P + E HL KEL+ V+ +LQ+QV+ N+ + LN++QEE++ QEE++++ E
Sbjct: 295 LPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQE 354
Query: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
E++QEQ EK+R Q K + E++ + + + E++++ +E + E+ + +
Sbjct: 355 ERLQEQHEKLR-QLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQNQQL 413
Query: 374 EKEEKIRELEEKMHEQEKI-REQEEKRQEEEKIREQ-EKRQEQEAKMWRQEEKIREQEEK 431
+ + L + H E + E EE Q + E E R+ + M +EK + E
Sbjct: 414 TAQLNLMALPGEGHGGEHLDSEGEEAPQPMPSVPEDLESREAMSSFMDHLKEK-ADLSEL 472
Query: 432 IREQEKKM---WRQ--EEKIH 447
+++QE + W++ +KIH
Sbjct: 473 VKKQELRFIQYWQERCHQKIH 493
Score = 87.8 bits (216), Expect = 3e-17
Identities = 75/330 (22%), Positives = 164/330 (49%), Gaps = 41/330 (12%)
Query: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWR 420
K+ RL+ + +++ +++E ++ E++K + +K + E +++ Q +++E ++
Sbjct: 92 KISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLYH 151
Query: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEK-----IREEEKRQEQ-------EEMWRQE 468
E +R EE+ ++ ++ + E E+ I E+K+ Q W E
Sbjct: 152 MERSLRYFEEESKDLAVRLQHSLQCKGELERALSAVIATEKKKANQLSSCSKAHTEWELE 211
Query: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI--- 525
+ +++Q + Q ++ E Q+ ++ R E H + E+ R ++M + ++I
Sbjct: 212 QSLQDQALLKAQLTQLKESF----QQLQLERDECAEHIEGERAR-WHQRMSKMLQEICTL 266
Query: 526 -REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQ---EQEKMRRQEEKIREQEEKIR 581
+E+++ +R EE R ++ + E + + + E + +R++ E++ + +
Sbjct: 267 KKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQV 326
Query: 582 EQKEKI----REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637
+ + I R QEE+I EQEE++R+QEE +QEQ EK+ Q K Q E++
Sbjct: 327 KNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL--------RQLAKPQSVFEELN 378
Query: 638 RQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
+ + + E ++++ +EK+ E EHLEAA
Sbjct: 379 NENKSTLQLEQQVKELQEKLGE--EHLEAA 406
Score = 83.2 bits (204), Expect = 7e-16
Identities = 76/333 (22%), Positives = 162/333 (48%), Gaps = 36/333 (10%)
Query: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
+QQ++++ Q E+ ++ + Q+ E ++ Q + + Q+E++ ++ E +R E
Sbjct: 104 KQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTD---LYHMERSLRYFE 160
Query: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415
E E ++ RL+ + K E R L + ++K Q + E E+ + +
Sbjct: 161 E---ESKDLAVRLQHSLQCKGELERALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQ 217
Query: 416 AKMWRQEEKIREQEEKIR----------EQEKKMWRQE-EKIHEQEKIREEEKRQEQEEM 464
A + Q +++E ++++ E E+ W Q K+ ++ ++EK+Q+
Sbjct: 218 ALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTLKKEKQQD---- 273
Query: 465 WRQEEKIREQEEIWRQKEKMHEQ--EKIRKQEEKVWRQEEKMHDQEE--KIREQEEKMWR 520
+R EE+ R K+ Q E + + V + E H ++E ++ + + +
Sbjct: 274 ------MRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVK 327
Query: 521 QEEKI----REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
+ I R QEE+IREQEE++R+QEE +QEQ EK+ + + E++ + + +
Sbjct: 328 NNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQL 387
Query: 577 EEKIREQKEKIREQE-EKIWEQEEKIREQEEMM 608
E++++E +EK+ E+ E +Q +++ Q +M
Sbjct: 388 EQQVKELQEKLGEEHLEAASQQNQQLTAQLNLM 420
Score = 78.2 bits (191), Expect = 2e-14
Identities = 66/327 (20%), Positives = 157/327 (48%), Gaps = 28/327 (8%)
Query: 315 KIQEQEEKIREQEEKIREQ--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
+++ + +++Q++++ Q EEK E E+E +++ Q ++ +KEE L +
Sbjct: 95 RLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQT-LIIQKEE----LNTDL 149
Query: 373 WEKEEKIRELEEKMHE-----QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 427
+ E +R EE+ + Q ++ + E + + EK++ + + E
Sbjct: 150 YHMERSLRYFEEESKDLAVRLQHSLQCKGELERALSAVIATEKKKANQLSSCSKAHTEWE 209
Query: 428 QEEKIREQ---EKKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQKE 482
E+ +++Q + ++ + +E + + R+E E + + W Q QE +KE
Sbjct: 210 LEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTLKKE 269
Query: 483 KMHEQEKIRKQEEKVWRQEEKMHD----------QEEKIREQEEKMWRQEEKIREQEEKI 532
K + ++ + E + + + +M + E +++ +++ R +++ Q +
Sbjct: 270 KQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNN 329
Query: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
+ R QEE ++EQEE++ +QEE++QEQ + RQ K + E++ + + + E+
Sbjct: 330 QHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQ 389
Query: 593 KIWEQEEKIREQE-EMMQEQEEKMWEQ 618
++ E +EK+ E+ E +Q +++ Q
Sbjct: 390 QVKELQEKLGEEHLEAASQQNQQLTAQ 416
>gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 595
Score = 147 bits (372), Expect = 2e-35
Identities = 124/447 (27%), Positives = 219/447 (48%), Gaps = 108/447 (24%)
Query: 51 MSKETRQSKLAEAKEQLTDHHPQTNPSVGTAASDTKKKKINNGTNPETTTSGGCH----- 105
M++ET+ +KLA AK++L ++ + P V + +K NG+ PET TSGGCH
Sbjct: 1 MAEETQHNKLAAAKKKLKEYWQKNRPRVPAGVNRNRK---TNGSIPETATSGGCHLSPHS 57
Query: 106 -----------SP------------------------------------EDEQKASHQHQ 118
SP E+E+KA+++ Q
Sbjct: 58 CSTSSSLHAPQSPCQERAVVLDSTSVKISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQ 117
Query: 119 EALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELE 178
+A RELE Q+ T+ I QK EL LY+ + +++ E E++DL RL S + GELE
Sbjct: 118 KA-ERELEVQIQTLII---QKEELNTDLYHMERSLRYFEEESKDLAVRLQHSLQCKGELE 173
Query: 179 QALSAV-ATQKKKADRY-----------IEELTKERDALSLELYRNTITDEELK------ 220
+ALSAV AT+KKKA++ +E+ +++ L +L + + ++L+
Sbjct: 174 RALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLKESFQQLQLERDEC 233
Query: 221 ------------EKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL--------PQ 260
++ +K+ +++ ++ EK + V+EL+R L + K + P
Sbjct: 234 AEHIEGERARWHQRMSKMLQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPA 293
Query: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
+ E HL KEL+ V+ +LQ+QV+ N+ + LN++QEE++ QEE++++ EE++QEQ
Sbjct: 294 VPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQH 353
Query: 321 EKIREQE------EKIREQEEKMRRQEEMMWEKEEKMR--RQEEMMWEKEEKMRR---LE 369
EK+R+ E++ + + + E+ + E +EK+ ++ E +KE + R
Sbjct: 354 EKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKETETSAQKEPEAARGPGAP 413
Query: 370 EMMWEKEEKIRELEEKMHEQEKIREQE 396
E + L+EK E +++QE
Sbjct: 414 GPGGESSSFMDHLKEKADLSELVKKQE 440
Score = 84.0 bits (206), Expect = 4e-16
Identities = 69/313 (22%), Positives = 154/313 (49%), Gaps = 43/313 (13%)
Query: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWR 420
K+ RL+ + +++ +++E ++ E++K + +K + E +++ Q +++E ++
Sbjct: 84 KISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTDLYH 143
Query: 421 QEEKIREQEEKIREQEKKMWRQEEKIHEQEK-----IREEEKRQEQ-------EEMWRQE 468
E +R EE+ ++ ++ + E E+ I E+K+ Q W E
Sbjct: 144 MERSLRYFEEESKDLAVRLQHSLQCKGELERALSAVIATEKKKANQLSSCSKAHTEWELE 203
Query: 469 EKIREQEEIWRQKEKMHE---QEKIRKQE--EKVWRQEEKMHDQEEKI--------REQE 515
+ +++Q + Q ++ E Q ++ + E E + + + H + K+ +E++
Sbjct: 204 QSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTLKKEKQ 263
Query: 516 EKMWRQEEKIREQEEKIREQEEKIR----------EQEEMMQEQEEKMGEQEEKMQEQEK 565
+ M R EE R + + E + E + + +E E GE + +++ +
Sbjct: 264 QDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQH 323
Query: 566 M----RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
+ RRQEE+IREQEE++R+Q+E+++EQ EK+ Q K + E + + + + E++
Sbjct: 324 ISLLNRRQEERIREQEERLRKQEERLQEQHEKL-RQLAKPQSVFEELNNENKSTLQLEQQ 382
Query: 622 MCEQEEKMQEQEE 634
+ E +EK+ E +E
Sbjct: 383 VKELQEKLGEVKE 395
Score = 82.8 bits (203), Expect = 9e-16
Identities = 72/321 (22%), Positives = 152/321 (47%), Gaps = 25/321 (7%)
Query: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
K L+ +++ Q+EE + N Q+ E ++ E +IQ + +E + E +R
Sbjct: 93 KSLKQQKKQVEHQLEEEKKANNERQKAEREL---EVQIQTLIIQKEELNTDLYHMERSLR 149
Query: 332 EQEEKMR----RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
EE+ + R + + K E R ++ +++K +L K ELE+ +
Sbjct: 150 YFEEESKDLAVRLQHSLQCKGELERALSAVIATEKKKANQLSSC--SKAHTEWELEQSLQ 207
Query: 388 EQEKIREQEEKRQE---EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
+Q ++ Q + +E + ++ E + E + R +++ + ++I +K+ +
Sbjct: 208 DQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTLKKEKQQDMR 267
Query: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
++ E E+ + K Q E + + + + E+ + +RK+ E+V + +
Sbjct: 268 RVEELERSLSKLKNQMAEPLPPEPPAVPSEVEL----------QHLRKELERVAGELQSQ 317
Query: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
+ I RQEE+IREQEE++R+QEE+++EQ E +++ + EE E +
Sbjct: 318 VKNNQHISLLNR---RQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENK 374
Query: 565 KMRRQEEKIREQEEKIREQKE 585
+ E++++E +EK+ E KE
Sbjct: 375 STLQLEQQVKELQEKLGEVKE 395
Score = 81.3 bits (199), Expect = 3e-15
Identities = 73/316 (23%), Positives = 154/316 (48%), Gaps = 35/316 (11%)
Query: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 355
+QQ++++ Q E+ ++ + Q+ E ++ Q + + Q+E++ ++ E +R E
Sbjct: 96 KQQKKQVEHQLEEEKKANNERQKAERELEVQIQTLIIQKEELNTD---LYHMERSLRYFE 152
Query: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415
E E ++ RL+ + K E R L + ++K Q + E E+ + +
Sbjct: 153 E---ESKDLAVRLQHSLQCKGELERALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQ 209
Query: 416 AKMWRQEEKIREQEEKIR----------EQEKKMWRQE-EKIHEQEKIREEEKRQEQEEM 464
A + Q +++E ++++ E E+ W Q K+ ++ ++EK+Q+
Sbjct: 210 ALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTLKKEKQQD---- 265
Query: 465 WRQEEKIREQEEIWRQKEKMHEQ--EKIRKQEEKVWRQEEKMHDQEE--KIREQEEKMWR 520
+R EE+ R K+ Q E + + V + E H ++E ++ + + +
Sbjct: 266 ------MRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVK 319
Query: 521 QEEKI----REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
+ I R QEE+IREQEE++R+QEE +QEQ EK+ + + E++ + + +
Sbjct: 320 NNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQL 379
Query: 577 EEKIREQKEKIREQEE 592
E++++E +EK+ E +E
Sbjct: 380 EQQVKELQEKLGEVKE 395
Score = 77.0 bits (188), Expect = 5e-14
Identities = 64/314 (20%), Positives = 151/314 (48%), Gaps = 27/314 (8%)
Query: 315 KIQEQEEKIREQEEKIREQ--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372
+++ + +++Q++++ Q EEK E E+E +++ Q ++ +KEE L +
Sbjct: 87 RLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQIQT-LIIQKEE----LNTDL 141
Query: 373 WEKEEKIRELEEKMHE-----QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 427
+ E +R EE+ + Q ++ + E + + EK++ + + E
Sbjct: 142 YHMERSLRYFEEESKDLAVRLQHSLQCKGELERALSAVIATEKKKANQLSSCSKAHTEWE 201
Query: 428 QEEKIREQ---EKKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQKE 482
E+ +++Q + ++ + +E + + R+E E + + W Q QE +KE
Sbjct: 202 LEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTLKKE 261
Query: 483 KMHEQEKIRKQEEKVWRQEEKMHD----------QEEKIREQEEKMWRQEEKIREQEEKI 532
K + ++ + E + + + +M + E +++ +++ R +++ Q +
Sbjct: 262 KQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNN 321
Query: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
+ R QEE ++EQEE++ +QEE++QEQ + RQ K + E++ + + + E+
Sbjct: 322 QHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQ 381
Query: 593 KIWEQEEKIREQEE 606
++ E +EK+ E +E
Sbjct: 382 QVKELQEKLGEVKE 395
Score = 69.7 bits (169), Expect = 8e-12
Identities = 64/294 (21%), Positives = 135/294 (45%), Gaps = 18/294 (6%)
Query: 378 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 437
KI L+ + ++ ++Q E + EEEK + +RQ+ E ++ Q + + Q+E++
Sbjct: 84 KISRLKNTIKSLKQQKKQVEHQLEEEK-KANNERQKAERELEVQIQTLIIQKEELNTDLY 142
Query: 438 KMWRQEEKIHEQEK---IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE 494
M R E+ K +R + Q + E+ R + I +K+K ++ K
Sbjct: 143 HMERSLRYFEEESKDLAVRLQHSLQCKGELERALSAV-----IATEKKKANQLSSCSKAH 197
Query: 495 EKVWRQEEKMHDQE------EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQE 548
+ W E+ + DQ +++E +++ + ++ E E R + + +M+QE
Sbjct: 198 TE-WELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIEGERARWHQ--RMSKMLQE 254
Query: 549 QEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMM 608
E+++ M+ E++ R K++ Q + + E ++ +++ +
Sbjct: 255 ICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGEL 314
Query: 609 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Q Q + QEE+++EQEE++R+QEE++ EQ +LRQ + +E
Sbjct: 315 QSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEE 368
Score = 58.9 bits (141), Expect = 1e-08
Identities = 66/339 (19%), Positives = 137/339 (40%), Gaps = 95/339 (28%)
Query: 408 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE----- 462
Q QE+ + KI + I+ +++ + E ++ E++K E ++ E+E
Sbjct: 68 QSPCQERAVVLDSTSVKISRLKNTIKSLKQQKKQVEHQLEEEKKANNERQKAERELEVQI 127
Query: 463 ------------EMWRQEEKIREQEE--------------------------IWRQKEKM 484
+++ E +R EE I +K+K
Sbjct: 128 QTLIIQKEELNTDLYHMERSLRYFEEESKDLAVRLQHSLQCKGELERALSAVIATEKKKA 187
Query: 485 HEQEKIRKQEEKVWRQEEKMHDQE------EKIREQEEKMWRQEEKIREQEEKIREQEEK 538
++ K + W E+ + DQ +++E +++ + ++ E E E+
Sbjct: 188 NQLSSCSKAHTE-WELEQSLQDQALLKAQLTQLKESFQQLQLERDECAEHIE--GERARW 244
Query: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQE-----------------EKIR 581
+ +M+QE E+++ M+ E++ R K++ Q + +R
Sbjct: 245 HQRMSKMLQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLR 304
Query: 582 EQKEKI------------------REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMC 623
++ E++ R QEE+I EQEE++R+QEE +QEQ EK+
Sbjct: 305 KELERVAGELQSQVKNNQHISLLNRRQEERIREQEERLRKQEERLQEQHEKL-------- 356
Query: 624 EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Q K Q E++ + + + E ++++ +EK+ E +E
Sbjct: 357 RQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKE 395
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.121 0.332
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,508,992
Number of Sequences: 37866
Number of extensions: 2053228
Number of successful extensions: 223096
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2078
Number of HSP's successfully gapped in prelim test: 1257
Number of HSP's that attempted gapping in prelim test: 16770
Number of HSP's gapped (non-prelim): 47744
length of query: 668
length of database: 18,247,518
effective HSP length: 109
effective length of query: 559
effective length of database: 14,120,124
effective search space: 7893149316
effective search space used: 7893149316
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.