Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 222136611
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
(510 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 1028 0.0
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 193 4e-49
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 150 3e-36
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 150 3e-36
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] 138 1e-32
gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 130 4e-30
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 130 4e-30
gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 125 7e-29
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 124 3e-28
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 124 3e-28
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 116 6e-26
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 91 2e-18
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 84 4e-16
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 83 7e-16
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 80 4e-15
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 77 5e-14
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 74 4e-13
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 74 4e-13
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 71 3e-12
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 70 3e-12
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 70 3e-12
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 70 3e-12
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 69 1e-11
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 67 5e-11
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 65 1e-10
gi|118572606 hemicentin 1 [Homo sapiens] 64 4e-10
gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens] 63 6e-10
gi|145275170 kin of IRRE-like 2 isoform a [Homo sapiens] 63 6e-10
gi|61742797 basal cell adhesion molecule isoform 2 precursor [Ho... 62 2e-09
gi|31543106 basal cell adhesion molecule isoform 1 precursor [Ho... 62 2e-09
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 1028 bits (2657), Expect = 0.0
Identities = 510/510 (100%), Positives = 510/510 (100%)
Query: 1 MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGE 60
MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGE
Sbjct: 1 MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGE 60
Query: 61 QVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQA 120
QVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQA
Sbjct: 61 QVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQA 120
Query: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPS 180
DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPS
Sbjct: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPS 180
Query: 181 VTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHIL 240
VTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHIL
Sbjct: 181 VTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHIL 240
Query: 241 HVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTL 300
HVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTL
Sbjct: 241 HVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTL 300
Query: 301 GFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALL 360
GFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALL
Sbjct: 301 GFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALL 360
Query: 361 FCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRA 420
FCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRA
Sbjct: 361 FCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRA 420
Query: 421 EGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRAEEEEDQDEGIKQ 480
EGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRAEEEEDQDEGIKQ
Sbjct: 421 EGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRAEEEEDQDEGIKQ 480
Query: 481 AMNHFVQENGTLRAKPTGNGIYINGRGHLV 510
AMNHFVQENGTLRAKPTGNGIYINGRGHLV
Sbjct: 481 AMNHFVQENGTLRAKPTGNGIYINGRGHLV 510
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 193 bits (490), Expect = 4e-49
Identities = 141/491 (28%), Positives = 224/491 (45%), Gaps = 68/491 (13%)
Query: 12 PEAWLLLLLLLASFTGRCPA--GELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWAR 69
P LLLL L F+ C A G + VT V G++ L C + E + Q++W +
Sbjct: 36 PPPLLLLLFPLLLFSRLCGALAGPIIVEPHVTAVWGKNVSLKCLI--EVNETITQISWEK 93
Query: 70 VDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRV 129
+ G+ +Q +A+ H +YG V Y+GRV N D ++ L N +D G+Y C+
Sbjct: 94 IH-GKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLN--DATITLHNIGFSDSGKYICKA 150
Query: 130 STFPAGSFQARLRLRVLVPPLPSLNPGP-ALEEGQGLTLAASC-TAEGSPAPSVTWDTEV 187
TFP G+ Q+ + VLV P SL GP +L +G T+AA C A G P + W+ ++
Sbjct: 151 VTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDL 210
Query: 188 KGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAE 247
S+ + + +A + S++ L P+R G+ +TCVV HP L +D R + IL + + E
Sbjct: 211 GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPE 270
Query: 248 ASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYN-WTRLDGPLPSGVRVDGDTLGF-PPL 305
SV G + W +GR+G LKC ++ PPP + W+RLDG P G+ +TL F PL
Sbjct: 271 VSVTGYDGN--WFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPL 328
Query: 306 TTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLV------------------- 346
T +SG+Y+C V+N R Q + + DP + Q +
Sbjct: 329 TFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPSTADIEDLATEPKKLP 388
Query: 347 ------------SASVVVVGVIAALLFCLLVVVVVLMSRYHRR---KAQQMTQKYEEELT 391
+ + ++ V+ LF +LV V+ + Y RR + + Y
Sbjct: 389 FPLSTLATIKDDTIATIIASVVGGALFIVLVSVLAGIFCYRRRRTFRGDYFAKNYIPPSD 448
Query: 392 LTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLKDNSSCSVMS-------EEPEGRS 444
+ +E+ I L D +PDS+K + V + EEPE
Sbjct: 449 MQKESQIDVLQQDELD--------------SYPDSVKKENKNPVNNLIRKDYLEEPEKTQ 494
Query: 445 YSTLTTVREIE 455
++ + + E
Sbjct: 495 WNNVENLNRFE 505
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 150 bits (378), Expect = 3e-36
Identities = 128/442 (28%), Positives = 211/442 (47%), Gaps = 41/442 (9%)
Query: 1 MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGD-SG 59
M L+ A W W L L L A F + ++ +D + +G D L C +
Sbjct: 4 MGLAGAAGRW----WGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPS 59
Query: 60 EQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQ 119
++ QV W + G Q +A+ + G+ V Y RVE P DG++ L
Sbjct: 60 VKITQVTWQKSTNGS-KQNVAIYNPSMGVSVLAPYRERVEFLRPSFT--DGTIRLSRLEL 116
Query: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPAL---EEGQ-GLTLAASCT-AE 174
DEG Y C +TFP G+ +++L L V+ P + A+ ++GQ L A+CT A
Sbjct: 117 EDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSAN 176
Query: 175 GSPAPSVTWDTEVKGTTSSRSFKH-SRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233
G P V+W+T +KG + ++ + + V S + LVPSR + Q L C+V++
Sbjct: 177 GKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
Query: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSG 292
+ +T L+V + E ++ G + W++ R L C ++ PP + Y+WT L+G LP G
Sbjct: 237 ESLT--LNVQYEPEVTIEGFDGN--WYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG 292
Query: 293 VRVDGDTLGFP-PLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVV 351
V TL F P+ +G Y+C +N +R QV V++ E Q L SA+ +
Sbjct: 293 VEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI---TEKPRPQRGLGSAARL 349
Query: 352 VVGVIAALLFCLLVVVVVLMSRYHRRKA-----------QQMTQKYEEELTLTRENSI-- 398
+ G +A +F +LV V+ + Y+R++ Q ++QK E + +R++S+
Sbjct: 350 LAGTVA--VFLILVAVLTVFFLYNRQQKSPPETDGAGTDQPLSQK--PEPSPSRQSSLVP 405
Query: 399 RRLHSHHTDP-RSQPEESVGLR 419
+ H DP R Q +E L+
Sbjct: 406 EDIQVVHLDPGRQQQQEEEDLQ 427
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 150 bits (378), Expect = 3e-36
Identities = 118/403 (29%), Positives = 192/403 (47%), Gaps = 29/403 (7%)
Query: 1 MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGD-SG 59
M L+ A W W L L L A F + ++ +D + +G D L C +
Sbjct: 4 MGLAGAAGRW----WGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPS 59
Query: 60 EQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQ 119
++ QV W + G Q +A+ + G+ V Y RVE P DG++ L
Sbjct: 60 VKITQVTWQKSTNGS-KQNVAIYNPSMGVSVLAPYRERVEFLRPSFT--DGTIRLSRLEL 116
Query: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPAL---EEGQ-GLTLAASCT-AE 174
DEG Y C +TFP G+ +++L L V+ P + A+ ++GQ L A+CT A
Sbjct: 117 EDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSAN 176
Query: 175 GSPAPSVTWDTEVKGTTSSRSFKH-SRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233
G P V+W+T +KG + ++ + + V S + LVPSR + Q L C+V++
Sbjct: 177 GKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
Query: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSG 292
+ +T L+V + E ++ G + W++ R L C ++ PP + Y+WT L+G LP G
Sbjct: 237 ESLT--LNVQYEPEVTIEGFDGN--WYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG 292
Query: 293 VRVDGDTLGFP-PLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD-----PQEDSGKQVDLV 346
V TL F P+ +G Y+C +N +R QV V++ + + G++ V
Sbjct: 293 VEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPV 352
Query: 347 SASVVVVGVIAALLFCLLVV---VVVLMSRYHRRKAQQMTQKY 386
+ ++ GV ++L L+VV VV L R H K T+K+
Sbjct: 353 -PTAIIGGVAGSILLVLIVVGGIVVALRRRRHTFKGDYSTKKH 394
>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
Length = 352
Score = 138 bits (347), Expect = 1e-32
Identities = 102/341 (29%), Positives = 164/341 (48%), Gaps = 20/341 (5%)
Query: 1 MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGD-SG 59
M L+ A W W L L L A F + ++ +D + +G D L C +
Sbjct: 4 MGLAGAAGRW----WGLALGLTAFFLPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPS 59
Query: 60 EQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQ 119
++ QV W + G Q +A+ + G+ V Y RVE P DG++ L
Sbjct: 60 VKITQVTWQKSTNGS-KQNVAIYNPSMGVSVLAPYRERVEFLRPSFT--DGTIRLSRLEL 116
Query: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPAL---EEGQ-GLTLAASCT-AE 174
DEG Y C +TFP G+ +++L L V+ P + A+ ++GQ L A+CT A
Sbjct: 117 EDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSAN 176
Query: 175 GSPAPSVTWDTEVKGTTSSRSFKH-SRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233
G P V+W+T +KG + ++ + + V S + LVPSR + Q L C+V++
Sbjct: 177 GKPPSVVSWETRLKGEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHMDRFK 236
Query: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSG 292
+ +T L+V + E ++ G + W++ R L C ++ PP + Y+WT L+G LP G
Sbjct: 237 ESLT--LNVQYEPEVTIEGFDGN--WYLQRMDVKLTCKADANPPATEYHWTTLNGSLPKG 292
Query: 293 VRVDGDTLGFP-PLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332
V TL F P+ +G Y+C +N +R QV V++
Sbjct: 293 VEAQNRTLFFKGPINYSLAGTYICEATNPIGTRSGQVEVNI 333
>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
Length = 392
Score = 130 bits (326), Expect = 4e-30
Identities = 107/366 (29%), Positives = 164/366 (44%), Gaps = 28/366 (7%)
Query: 14 AWLLLLLLLASFTGRCPAGELETSDVVTVV-------LGQDAKLPCFYRGDSGE--QVGQ 64
AW LLL+ L + P T DVV LG LPC+ + + E V Q
Sbjct: 8 AWPLLLVALLVLSWPPPG----TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQ 63
Query: 65 VAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGE 124
+ WAR GE +A+ H G S + + S+ + DEG
Sbjct: 64 LTWAR--HGESGS-MAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
Query: 125 YECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWD 184
Y C TFP GS + LRVL P + G+ + +A + G P +TW
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
Query: 185 TEVKG--TTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHV 242
+++ G TS S + VTS + LVPS ++G+ +TC V H + Q +T L V
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
Query: 243 SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSGVRVDGDTLG 301
+ E S+ G + N W++G+ A L C + P P+ YNW+ GPLP G L
Sbjct: 241 YYPPEVSISGYD--NNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLL 298
Query: 302 FPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD--PQEDSGKQVDLVSASVVVVGVIAAL 359
P+ + +C+V+N +R +++TV V + P E SG +S + ++ V+ L
Sbjct: 299 IRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG-----ISRNAIIFLVLGIL 353
Query: 360 LFCLLV 365
+F +L+
Sbjct: 354 VFLILL 359
>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
Length = 417
Score = 130 bits (326), Expect = 4e-30
Identities = 107/366 (29%), Positives = 164/366 (44%), Gaps = 28/366 (7%)
Query: 14 AWLLLLLLLASFTGRCPAGELETSDVVTVV-------LGQDAKLPCFYRGDSGE--QVGQ 64
AW LLL+ L + P T DVV LG LPC+ + + E V Q
Sbjct: 8 AWPLLLVALLVLSWPPPG----TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQ 63
Query: 65 VAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGE 124
+ WAR GE +A+ H G S + + S+ + DEG
Sbjct: 64 LTWAR--HGESGS-MAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
Query: 125 YECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWD 184
Y C TFP GS + LRVL P + G+ + +A + G P +TW
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
Query: 185 TEVKG--TTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHV 242
+++ G TS S + VTS + LVPS ++G+ +TC V H + Q +T L V
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
Query: 243 SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSGVRVDGDTLG 301
+ E S+ G + N W++G+ A L C + P P+ YNW+ GPLP G L
Sbjct: 241 YYPPEVSISGYD--NNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLL 298
Query: 302 FPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD--PQEDSGKQVDLVSASVVVVGVIAAL 359
P+ + +C+V+N +R +++TV V + P E SG +S + ++ V+ L
Sbjct: 299 IRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSG-----ISRNAIIFLVLGIL 353
Query: 360 LFCLLV 365
+F +L+
Sbjct: 354 VFLILL 359
>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
Length = 372
Score = 125 bits (315), Expect = 7e-29
Identities = 104/350 (29%), Positives = 155/350 (44%), Gaps = 23/350 (6%)
Query: 14 AWLLLLLLLASFTGRCPAGELETSDVVTVV-------LGQDAKLPCFYRGDSGE--QVGQ 64
AW LLL+ L + P T DVV LG LPC+ + + E V Q
Sbjct: 8 AWPLLLVALLVLSWPPPG----TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQ 63
Query: 65 VAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGE 124
+ WAR GE +A+ H G S + + S+ + DEG
Sbjct: 64 LTWAR--HGESGS-MAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
Query: 125 YECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWD 184
Y C TFP GS + LRVL P + G+ + +A + G P +TW
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
Query: 185 TEVKG--TTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHV 242
+++ G TS S + VTS + LVPS ++G+ +TC V H + Q +T L V
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
Query: 243 SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSGVRVDGDTLG 301
+ E S+ G + N W++G+ A L C + P P+ YNW+ GPLP G L
Sbjct: 241 YYPPEVSISGYD--NNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLL 298
Query: 302 FPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD--PQEDSGKQVDLVSAS 349
P+ + +C+V+N +R +++TV V + P E SG + SA+
Sbjct: 299 IRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASAN 348
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 124 bits (310), Expect = 3e-28
Identities = 121/467 (25%), Positives = 179/467 (38%), Gaps = 45/467 (9%)
Query: 12 PEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGD-SGEQVGQVAWARV 70
P W LLLLLL TG ++ V LG +LPC G + V W R
Sbjct: 16 PLLWPLLLLLLLE-TGAQDV-RVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRP 73
Query: 71 DAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPL------------------DGSV 112
DA Q +A H K G P++ P P L D ++
Sbjct: 74 DAPANHQNVAAFHPKMG----PSFPS----PKPGSERLSFVSAKQSTGQDTEAELQDATL 125
Query: 113 LLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCT 172
L DEG Y C +TFP GS + LRV+ P T+A +
Sbjct: 126 ALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCIS 185
Query: 173 AEGSPAPSVTW----DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228
EG P ++W D E K T S + + + VTS F LVPS +G +TC V H
Sbjct: 186 KEGRPPARISWLSSLDWEAKETQVSGTL--AGTVTVTSRFTLVPSGRADGVTVTCKVEHE 243
Query: 229 GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDG 287
+ I L V + E S+ G +D W++GR A L C P P+ Y+W+ G
Sbjct: 244 SFEEPALIPVTLSVRYPPEVSISGYDDN--WYLGRTDATLSCDVRSNPEPTGYDWSTTSG 301
Query: 288 PLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVS 347
P+ G L + + + +VC V+N ++ + V + +G +
Sbjct: 302 TFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPNTAGAG----A 357
Query: 348 ASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIR-RLHSHHT 406
++ G+IAA++ + +L+ R R+ +Q Q EE+ L S +
Sbjct: 358 TGGIIGGIIAAIIATAVAATGILICRQQRK--EQTLQGAEEDEDLEGPPSYKPPTPKAKL 415
Query: 407 DPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTTVRE 453
+ + P + L A H E E Y L T+ E
Sbjct: 416 EAQEMPSQLFTLGASEHSPLKTPYFDAGASCTEQEMPRYHELPTLEE 462
>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
Length = 364
Score = 124 bits (310), Expect = 3e-28
Identities = 103/350 (29%), Positives = 152/350 (43%), Gaps = 21/350 (6%)
Query: 14 AWLLLLLLLASFTGRCPAGELETSDVVTVV-------LGQDAKLPCFYRGDSGE--QVGQ 64
AW LLL+ L + P T DVV LG LPC+ + + E V Q
Sbjct: 8 AWPLLLVALLVLSWPPPG----TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQ 63
Query: 65 VAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGE 124
+ WAR GE +A+ H G S + + S+ + DEG
Sbjct: 64 LTWAR--HGESGS-MAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGN 120
Query: 125 YECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWD 184
Y C TFP GS + LRVL P + G+ + +A + G P +TW
Sbjct: 121 YTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWH 180
Query: 185 TEVKG--TTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHV 242
+++ G TS S + VTS + LVPS ++G+ +TC V H + Q +T L V
Sbjct: 181 SDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTV 240
Query: 243 SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDGPLPSGVRVDGDTLG 301
+ E S+ G + N W++G+ A L C + P P+ YNW+ GPLP G L
Sbjct: 241 YYPPEVSISGYD--NNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLL 298
Query: 302 FPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVV 351
P+ + +C+V+N +R +++TV V + S VS S V
Sbjct: 299 IRPVDKPINTTLICNVTNALGARQAELTVQVKGTEHASASANGHVSYSAV 348
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 116 bits (290), Expect = 6e-26
Identities = 107/395 (27%), Positives = 156/395 (39%), Gaps = 47/395 (11%)
Query: 12 PEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGD-SGEQVGQVAWARV 70
P W LLLLLL TG ++ V LG +LPC G + V W R
Sbjct: 16 PLLWPLLLLLLLE-TGAQDV-RVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRP 73
Query: 71 DAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPL------------------DGSV 112
DA Q +A H K G P++ P P L D ++
Sbjct: 74 DAPANHQNVAAFHPKMG----PSFPS----PKPGSERLSFVSAKQSTGQDTEAELQDATL 125
Query: 113 LLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCT 172
L DEG Y C +TFP GS + LRV+ P T+A +
Sbjct: 126 ALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCIS 185
Query: 173 AEGSPAPSVTW----DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228
EG P ++W D E K T S + + + VTS F LVPS +G +TC V H
Sbjct: 186 KEGRPPARISWLSSLDWEAKETQVSGTL--AGTVTVTSRFTLVPSGRADGVTVTCKVEHE 243
Query: 229 GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS-YNWTRLDG 287
+ I L V + E S+ G +D W++GR A L C P P+ Y+W+ G
Sbjct: 244 SFEEPALIPVTLSVRYPPEVSISGYDDN--WYLGRTDATLSCDVRSNPEPTGYDWSTTSG 301
Query: 288 PLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVS 347
P+ G L + + + +VC V+N ++ + V + S + V
Sbjct: 302 TFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDV---- 357
Query: 348 ASVVVVGVIAALLFCLLVV----VVVLMSRYHRRK 378
+V G + L LL++ + ++ R RR+
Sbjct: 358 -GPLVWGAVGGTLLVLLLLAGGSLAFILLRVRRRR 391
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 91.3 bits (225), Expect = 2e-18
Identities = 107/390 (27%), Positives = 167/390 (42%), Gaps = 45/390 (11%)
Query: 12 PEAWLLLLLLLASFTGRCPAGE---LETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWA 68
P L LLLLL S P G+ L T DV TV+ G+ A + C S + V Q+
Sbjct: 22 PGLRLRLLLLLFSAAALIPTGDGQNLFTKDV-TVIEGEVATISCQVN-KSDDSVIQLL-- 77
Query: 69 RVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECR 128
Q + Y P + R + + L V L N +DEG Y C+
Sbjct: 78 ----NPNRQTI------YFRDFRPLKDSRFQLLNFSSSEL--KVSLTNVSISDEGRYFCQ 125
Query: 129 VSTFPAGSFQARLRLRVLVPP---LPSLNPGPALEEGQGLTLAASCTAEGS-PAPSVTW- 183
+ T P ++ + VLVPP + + A+E G + +CTA S PA ++ W
Sbjct: 126 LYTDPPQ--ESYTTITVLVPPRNLMIDIQKDTAVE---GEEIEVNCTAMASKPATTIRWF 180
Query: 184 --DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILH 241
+TE+KG + + S VTS+ L + +G P+ C V HP + + + L
Sbjct: 181 KGNTELKGKSEVEEW--SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLE 238
Query: 242 VSFLAEASVRGLEDQNLWHIGREGAMLK--CLSEGQPPP-SYNWTRLDGPLPSGVRVDGD 298
V + + ++ L + REG L+ C + G+P P W R+D +P + G
Sbjct: 239 VQYKPQVHIQ--MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGP 296
Query: 299 TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP---QEDSGKQVDLVSASVVVVGV 355
L L +G Y C SN S + V D +E S + VD V+ GV
Sbjct: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVD----HAVIGGV 352
Query: 356 IAALLFCLLVVVVVLMSRYHRRKAQQMTQK 385
+A ++F +L ++++L + R K T +
Sbjct: 353 VAVVVFAMLCLLIILGRYFARHKGTYFTHE 382
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 83.6 bits (205), Expect = 4e-16
Identities = 108/418 (25%), Positives = 168/418 (40%), Gaps = 73/418 (17%)
Query: 12 PEAWLLLLLLLASFTGRCPAGE---LETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWA 68
P L LLLLL S P G+ L T DV TV+ G+ A + C S + V Q+
Sbjct: 22 PGLRLRLLLLLFSAAALIPTGDGQNLFTKDV-TVIEGEVATISCQVN-KSDDSVIQLL-- 77
Query: 69 RVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECR 128
Q + Y P + R + + L V L N +DEG Y C+
Sbjct: 78 ----NPNRQTI------YFRDFRPLKDSRFQLLNFSSSEL--KVSLTNVSISDEGRYFCQ 125
Query: 129 VSTFPAGSFQARLRLRVLVPP---LPSLNPGPALEEGQGLTLAASCTAEGS-PAPSVTW- 183
+ T P ++ + VLVPP + + A+E G + +CTA S PA ++ W
Sbjct: 126 LYTDPPQ--ESYTTITVLVPPRNLMIDIQKDTAVE---GEEIEVNCTAMASKPATTIRWF 180
Query: 184 --DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILH 241
+TE+KG + + S VTS+ L + +G P+ C V HP + + + L
Sbjct: 181 KGNTELKGKSEVEEW--SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLE 238
Query: 242 VSFLAEASVRGLEDQNLWHIGREGAMLK--CLSEGQPPP-SYNWTRLDGPLPSGVRVDGD 298
V + + ++ L + REG L+ C + G+P P W R+D +P + G
Sbjct: 239 VQYKPQVHIQ--MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGP 296
Query: 299 TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP----------------------- 335
L L +G Y C SN S + V DP
Sbjct: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILT 356
Query: 336 --------QEDSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQK 385
+E S + VD V+ GV+A ++F +L ++++L + R K T +
Sbjct: 357 IITDSRAGEEGSIRAVD----HAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHE 410
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 82.8 bits (203), Expect = 7e-16
Identities = 104/394 (26%), Positives = 159/394 (40%), Gaps = 45/394 (11%)
Query: 9 MWGPEAWLLLLLLLASFTGRCPAGELETSDVV------TVVLGQDAKLPCFYRG--DSGE 60
M P A LLLLLLL + L D TVV G L C + DS
Sbjct: 1 MGAPAASLLLLLLLFACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSL 60
Query: 61 QVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQA 120
Q A + GE + AL ++ L S P + S+ + N A
Sbjct: 61 QWSNPAQQTLYFGE---KRALRDNRIQLVTS--------------TPHELSISISNVALA 103
Query: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGS-PAP 179
DEGEY C + T P + A+ + VL P + G + T +C + GS PA
Sbjct: 104 DEGEYTCSIFTMPVRT--AKSLVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAA 161
Query: 180 SVTW---DTEVKGT-TSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLL-QDQ 234
+TW D E+ G T + + ++ V+S +R +G + C V+H L D+
Sbjct: 162 RLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADR 221
Query: 235 RITHILHVSFLAEASVRGLEDQNLWHIGREGA--MLKCLSEGQP-PPSYNWTRLDGPLPS 291
+ + V + A +R REG +L C G P P Y W + +G +P
Sbjct: 222 STSQRIEVLYTPTAMIRPDPPHP-----REGQKLLLHCEGRGNPVPQQYLWEK-EGSVPP 275
Query: 292 GVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVV 351
L FP L SG Y C ++ S + T++V DP S + +
Sbjct: 276 LKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP---SPVPSSSSTYHAI 332
Query: 352 VVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQK 385
+ G++A ++F LL++++ L R K +T +
Sbjct: 333 IGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHE 366
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 80.1 bits (196), Expect = 4e-15
Identities = 76/288 (26%), Positives = 125/288 (43%), Gaps = 20/288 (6%)
Query: 107 PLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLT 166
P + S+ + N ADEGEY C + T P + A+ + VL P + G + T
Sbjct: 124 PHELSISISNVALADEGEYTCSIFTMPVRT--AKSLVTVLGIPQKPIITGYKSSLREKDT 181
Query: 167 LAASCTAEGS-PAPSVTW---DTEVKGT-TSSRSFKHSRSAAVTSEFHLVPSRSMNGQPL 221
+C + GS PA +TW D E+ G T + + ++ V+S +R +G +
Sbjct: 182 ATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQVTREDDGASI 241
Query: 222 TCVVSHPGLL-QDQRITHILHVSFLAEASVRGLEDQNLWHIGREGA--MLKCLSEGQP-P 277
C V+H L D+ + + V + A +R REG +L C G P P
Sbjct: 242 VCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPPHP-----REGQKLLLHCEGRGNPVP 296
Query: 278 PSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQE 337
Y W + +G +P L FP L SG Y C ++ S + T++V DP
Sbjct: 297 QQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYTLNVNDP-- 353
Query: 338 DSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQK 385
S + ++ G++A ++F LL++++ L R K +T +
Sbjct: 354 -SPVPSSSSTYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHE 400
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 76.6 bits (187), Expect = 5e-14
Identities = 75/296 (25%), Positives = 127/296 (42%), Gaps = 31/296 (10%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPA-LEEGQGLTLAASCT 172
L N DEG+Y+C V+ ++ + +L V +PS P L G C
Sbjct: 567 LFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTV--NEMPSFLKTPMDLTIRTGAMARLECA 624
Query: 173 AEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSE--FHLVPSRSMNGQPLTCVVSHP-- 228
AEG PAP ++W + G T + + R + + F + + + +C+ +
Sbjct: 625 AEGHPAPQISWQKD--GGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQNTAG 682
Query: 229 GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGP 288
GL + +T + SF +R LED+ + E A+L+C++ G P P NWT+ DGP
Sbjct: 683 GLSANASLTVLETPSF-----IRPLEDKTVTR--GETAVLQCIAGGSPAPRLNWTKDDGP 735
Query: 289 LPSGVR----VDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVD 344
L R L E +G Y C +SN + + ++V+ Q
Sbjct: 736 LLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPNCDSSQSS 795
Query: 345 L-------VSASVVVVGVIAALLFCLLVVVVVLMSRYH-RRKAQQMTQKYEEELTL 392
+ + +V++ V+ ++ L+ V+V+ YH RRK + + EEL L
Sbjct: 796 IGHEDDGWTTVGIVIIVVVCCVVGTSLIWVIVI---YHMRRKNEDYSITNTEELNL 848
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 73.6 bits (179), Expect = 4e-13
Identities = 72/285 (25%), Positives = 119/285 (41%), Gaps = 31/285 (10%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPA-LEEGQGLTLAASCT 172
LR A EG+Y+C +S S+ + +L V + LPS P L G C
Sbjct: 568 LREVEFASEGKYQCVISNHFGSSYSVKAKLTVNM--LPSFTKTPMDLTIRAGAMARLECA 625
Query: 173 AEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSE--FHLVPSRSMNGQPLTCVVSHPG- 229
A G PAP + W + G T + + R + + F +V + + +C +
Sbjct: 626 AVGHPAPQIAWQKD--GGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAG 683
Query: 230 -LLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGP 288
+ + +T + SFL R L D+ + E A+L+C++ G PPP NWT+ D P
Sbjct: 684 SISANATLTVLETPSFL-----RPLLDRTVTK--GETAVLQCIAGGSPPPKLNWTKDDSP 736
Query: 289 LPSGVR----VDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVL-----DPQEDS 339
L R L +G Y C +SN + V + V+ D + +
Sbjct: 737 LVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQMT 796
Query: 340 GKQVD---LVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQ 381
+D + VV++ V+ ++ LV VV++ YH R+ +
Sbjct: 797 APSLDDDGWATVGVVIIAVVCCVVGTSLVWVVII---YHTRRRNE 838
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 73.6 bits (179), Expect = 4e-13
Identities = 72/285 (25%), Positives = 119/285 (41%), Gaps = 31/285 (10%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPA-LEEGQGLTLAASCT 172
LR A EG+Y+C +S S+ + +L V + LPS P L G C
Sbjct: 508 LREVEFASEGKYQCVISNHFGSSYSVKAKLTVNM--LPSFTKTPMDLTIRAGAMARLECA 565
Query: 173 AEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSE--FHLVPSRSMNGQPLTCVVSHPG- 229
A G PAP + W + G T + + R + + F +V + + +C +
Sbjct: 566 AVGHPAPQIAWQKD--GGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAG 623
Query: 230 -LLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGP 288
+ + +T + SFL R L D+ + E A+L+C++ G PPP NWT+ D P
Sbjct: 624 SISANATLTVLETPSFL-----RPLLDRTVTK--GETAVLQCIAGGSPPPKLNWTKDDSP 676
Query: 289 LPSGVR----VDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVL-----DPQEDS 339
L R L +G Y C +SN + V + V+ D + +
Sbjct: 677 LVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQMT 736
Query: 340 GKQVD---LVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQ 381
+D + VV++ V+ ++ LV VV++ YH R+ +
Sbjct: 737 APSLDDDGWATVGVVIIAVVCCVVGTSLVWVVII---YHTRRRNE 778
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 70.9 bits (172), Expect = 3e-12
Identities = 82/314 (26%), Positives = 132/314 (42%), Gaps = 28/314 (8%)
Query: 112 VLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEG--QGLTLAA 169
+ L +A DEG Y C++ T + L VLV P NP + E +G +
Sbjct: 89 IRLSDARLEDEGGYFCQLYT--EDTHHQIATLTVLVAPE---NPVVEVREQAVEGGEVEL 143
Query: 170 SCTAEGS-PAPSVTW---DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVV 225
SC S PA ++ W E+KG +SS+ S A T F + R +G + C
Sbjct: 144 SCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSVASTVRFRV--DRKDDGGIIICEA 201
Query: 226 SHPGLLQ--DQRITHILHVSFLAEASVRGLEDQNLWHIGREG--AMLKCLSEGQPPPSY- 280
+ L ++ ++L V + A + + + REG +L C G P P+
Sbjct: 202 QNQALPSGHSKQTQYVLDVQYSPTARIHASQA-----VVREGDTLVLTCAVTGNPRPNQI 256
Query: 281 NWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSG 340
W R + LP G+TL P L + +G Y C SN+ + + V DP
Sbjct: 257 RWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHARALYVLVVYDPGAVVE 316
Query: 341 KQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRR 400
Q + A +V G++A L+F ++ V+V ++ R+K +T E L + R
Sbjct: 317 AQTSVPYA--IVGGILALLVFLIICVLVGMVWCSVRQKGSYLT---HEASGLDEQGEARE 371
Query: 401 LHSHHTDPRSQPEE 414
+ +D + EE
Sbjct: 372 AFLNGSDGHKRKEE 385
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 70.5 bits (171), Expect = 3e-12
Identities = 62/218 (28%), Positives = 91/218 (41%), Gaps = 24/218 (11%)
Query: 110 GSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAA 169
G + + +A D G Y C ++ AGS + RL V VPP+ N P L +G
Sbjct: 2809 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIE-NGLPDLSTTEGSHAFL 2866
Query: 170 SCTAEGSPAPSVTWDTE---VKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQ---PLTC 223
C A GSP P++TWD + V G + + S V +++ GQ TC
Sbjct: 2867 PCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLV---------KNLEGQDAGTYTC 2917
Query: 224 VVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWT 283
+ +R+ H++ L L +G + L+C + G P P WT
Sbjct: 2918 TAENAVGRARRRV----HLTILVLPVFTTLPGDRSLRLG-DRLWLRCAARGSPTPRIGWT 2972
Query: 284 RLDGPLPSGV--RVDGDTLGFPPLTTEHSGIYVCHVSN 319
D P+ GV + G TL ++ E SG YVC N
Sbjct: 2973 VNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAEN 3010
Score = 65.9 bits (159), Expect = 9e-11
Identities = 69/239 (28%), Positives = 102/239 (42%), Gaps = 30/239 (12%)
Query: 108 LDGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP---LPSLNPGPALEEGQ 163
+DG VL + A +D G Y C V++ AGS + R LRV VPP LP PGP L
Sbjct: 745 VDGRVLRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVN-- 801
Query: 164 GLTLAASCTAEGSPAPSVTW-----DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNG 218
+ +C A G+P+P++ W GT + F R + S +R+ +
Sbjct: 802 -TPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLAS------ARASDS 854
Query: 219 QPLTCV-VSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPP 277
+CV VS G + R +L V S+ G E+ N+ + E L+C S PP
Sbjct: 855 GRYSCVAVSAVG---EDRQDVVLQVHM--PPSILG-EELNVSVVANESVALECQSHAMPP 908
Query: 278 PSYNWTRLDGPLP--SGVRVDGD--TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332
P +W + PL GV + D L +G Y C N+ + ++V
Sbjct: 909 PVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNV 967
Score = 61.6 bits (148), Expect = 2e-09
Identities = 59/225 (26%), Positives = 92/225 (40%), Gaps = 13/225 (5%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP--ALEEGQGLTLAASC 171
L A +D G Y C+ S G+ + RL V VPP G ++ G +A C
Sbjct: 369 LGRAQSSDAGVYTCKASN-AVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALEC 427
Query: 172 TAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLL 231
A G P+P+++W E S SR S L + +CV S P
Sbjct: 428 VARGHPSPTLSWHHEGLPVAESNE---SRLETDGSVLRLESPGEASSGLYSCVASSPA-- 482
Query: 232 QDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLP- 290
+ + + + V + V Q +G+ L C + G P P+ W + P
Sbjct: 483 GEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQP-LELPCQASGSPVPTIQWLQNGRPAEE 541
Query: 291 -SGVRV--DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332
+GV+V G TL + +HSG++ C +NE + ++V V V
Sbjct: 542 LAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 586
Score = 60.8 bits (146), Expect = 3e-09
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 13/228 (5%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTA 173
++ A +D+G Y C+VS AG L V VPP + + G L +C
Sbjct: 1899 IQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDV 1957
Query: 174 EGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233
G PAP+VTW + SS + V+ L SR Q T +
Sbjct: 1958 SGVPAPTVTWLKDRMPVESS-----AVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAE 2012
Query: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGV 293
R ++ V G+ ++ G+E L C ++GQPPP W + PL +
Sbjct: 2013 ARKDFVVAVLVAPRIRSSGVAREHHVLEGQE-VRLDCEADGQPPPDVAWLKDGSPLGQDM 2071
Query: 294 ------RVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
+DG +L L +G Y C N TV+VL P
Sbjct: 2072 GPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVP 2119
Score = 58.2 bits (139), Expect = 2e-08
Identities = 86/340 (25%), Positives = 123/340 (36%), Gaps = 44/340 (12%)
Query: 30 PAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGL- 88
P L S +TV G L C RG ++ + GEGA GL
Sbjct: 971 PVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGA----------GLQ 1020
Query: 89 HVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVP 148
HVS GR+ + L A A EG Y C S S Q L+L V VP
Sbjct: 1021 HVSAV--GRL-------------LYLGQAQLAQEGTYTCECSNVVGNSSQD-LQLEVHVP 1064
Query: 149 PLPS--LNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTS 206
P + P + Q C A G P P+VTW+ + + + +
Sbjct: 1065 PQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG---Q 1121
Query: 207 EFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLED--QNLWHIGRE 264
H+ +++ + +CV + R +S L + G D N+
Sbjct: 1122 SLHVERAQAAHTGRYSCVAENLA----GRAERKFELSVLVPPELIGDLDPLTNITAALHS 1177
Query: 265 GAMLKCLSEGQPPPSYNWTRLDGPLPSG----VRVDGDTLGFPPLTTEHSGIYVCHVSNE 320
L C + G PPP+ W R + P+ G + G L + SG+Y C SNE
Sbjct: 1178 PLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNE 1237
Query: 321 FSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALL 360
+V+VL P S + DL V+ G A L+
Sbjct: 1238 AGEARRNFSVEVLVP--PSIENEDLEEVIKVLDGQTAHLM 1275
Score = 57.0 bits (136), Expect = 4e-08
Identities = 76/310 (24%), Positives = 120/310 (38%), Gaps = 39/310 (12%)
Query: 42 VVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQP 101
V+ GQ+ +L C G+ VAW + D Q++ G H+ +G
Sbjct: 2038 VLEGQEVRLDC---EADGQPPPDVAWLK-DGSPLGQDM-------GPHLRFYLDG----- 2081
Query: 102 PPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPL--PSLNPGPAL 159
GS++L+ +D G Y C V+ PAG + VLVPP + L
Sbjct: 2082 --------GSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTL 2132
Query: 160 EEGQGLTLAASCTAEGSPAPSVTWDTE-VKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNG 218
G + C GSP V+W + + S R+ H + + + +
Sbjct: 2133 VSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTL----RISKVQLADA 2188
Query: 219 QPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAM-LKCLSEGQPP 277
TCV + P + D+ T + V + E +E QN + R + L C + G P
Sbjct: 2189 GIFTCVAASPAGVADRNFTLQVQVPPVLEP----VEFQNDVVVVRGSLVELPCEARGVPL 2244
Query: 278 PSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQ- 336
P +W + PL S G +L + SG Y C +E + V++P
Sbjct: 2245 PLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 2304
Query: 337 -EDSGKQVDL 345
EDSG+ +L
Sbjct: 2305 IEDSGQPTEL 2314
Score = 56.6 bits (135), Expect = 5e-08
Identities = 66/262 (25%), Positives = 95/262 (36%), Gaps = 31/262 (11%)
Query: 116 NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQ-------GLTLA 168
NA + D G+Y C V T G + VL+PP S + P E G TL
Sbjct: 1410 NAQKEDAGQYTC-VVTNELGEAVKNYHVEVLIPPSISKDD-PLGEVGVKEVKTKVNSTLT 1467
Query: 169 ASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228
C + P P++ W + + T S + + + P++ + CV ++
Sbjct: 1468 LECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL---LQIQPTQVSDSGRYLCVATNV 1524
Query: 229 GLLQDQRITHILHV--------SFLA-------EASVRGLEDQNLWHIGREGAMLKCLSE 273
DQ ++ V F A E RG + + A L C +
Sbjct: 1525 AGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTN 1584
Query: 274 GQPPPSYNWTRLDGPLPSGVRVD----GDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVT 329
PPP W R D PL +G V G L P + E++G Y C SNE
Sbjct: 1585 AIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYE 1644
Query: 330 VDVLDPQEDSGKQVDLVSASVV 351
+ VL P G +LV V
Sbjct: 1645 LLVLTPPVILGDTEELVEEVTV 1666
Score = 55.5 bits (132), Expect = 1e-07
Identities = 67/265 (25%), Positives = 102/265 (38%), Gaps = 36/265 (13%)
Query: 102 PPPRNPL--DGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPA 158
P PR + DG VL + A AD Y C V+ AGS + LRV VPP + G
Sbjct: 1697 PSPRLQVLEDGQVLQVSTAEVADAASYMC-VAENQAGSAEKLFTLRVQVPPRIA---GLD 1752
Query: 159 LEEGQGL---TLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVP--- 212
LE+ + +++ C P P VTW +K S++ ++ E L+P
Sbjct: 1753 LEQVTAILNSSVSLPCDVHAHPNPEVTW------------YKDSQALSLGEEVFLLPGTH 1800
Query: 213 ------SRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGA 266
+R + TC + + + + V + RG +D L +G + A
Sbjct: 1801 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVG-DKA 1859
Query: 267 MLKCLSEGQPPPSYNWTRLDGPLPSGVRVD----GDTLGFPPLTTEHSGIYVCHVSNEFS 322
+L C ++ P P+ W + PL R G L G+Y C VSN
Sbjct: 1860 VLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAG 1919
Query: 323 SRDSQVTVDVLDPQEDSGKQVDLVS 347
T+ V P + + VS
Sbjct: 1920 EAVRTFTLTVQVPPTFENPKTETVS 1944
Score = 54.3 bits (129), Expect = 3e-07
Identities = 56/235 (23%), Positives = 95/235 (40%), Gaps = 12/235 (5%)
Query: 109 DGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP-LPSLNPGPALEEGQGLT 166
DG VL + + DEG Y+C V+ PAG +LRV PP + N + +
Sbjct: 270 DGQVLRITGSHVGDEGRYQC-VAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHL 328
Query: 167 LAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVS 226
+ C A G P P++TW + +S ++R + L ++S + TC S
Sbjct: 329 VQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGG---RQLQLGRAQSSDAGVYTCKAS 385
Query: 227 HPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLD 286
+ ++ ++V E + G + + L+C++ G P P+ +W
Sbjct: 386 NAVGAAEKATRLDVYVPPTIEGA--GGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEG 443
Query: 287 GPL----PSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQE 337
P+ S + DG L SG+Y C S+ Q +V+V P +
Sbjct: 444 LPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQ 498
Score = 49.7 bits (117), Expect = 6e-06
Identities = 60/252 (23%), Positives = 97/252 (38%), Gaps = 16/252 (6%)
Query: 95 EGRVEQPPPPRNPLDGSVLLR--NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPS 152
+GR +P P + LL+ A D G Y C AG + L V V P+
Sbjct: 916 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALN-QAGRSEKHYNLNVWVAPVFP 974
Query: 153 LNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTT-SSRSFKHSRSAAVTSEFHLV 211
L L +G + SC G P P ++W + + +H +AV +L
Sbjct: 975 LRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQH--VSAVGRLLYLG 1032
Query: 212 PSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRG-LEDQNLWHIGREG-AMLK 269
++ TC S+ Q + +HV + G E + ++G A L+
Sbjct: 1033 QAQLAQEGTYTCECSNVVGNSSQDLQLEVHV----PPQIAGPREPPTQVSVVQDGVATLE 1088
Query: 270 CLSEGQPPPSYNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRD 325
C + G+PPP+ W R P+ + + + G +L H+G Y C N +
Sbjct: 1089 CNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 1148
Query: 326 SQVTVDVLDPQE 337
+ + VL P E
Sbjct: 1149 RKFELSVLVPPE 1160
Score = 48.9 bits (115), Expect = 1e-05
Identities = 73/305 (23%), Positives = 107/305 (35%), Gaps = 51/305 (16%)
Query: 34 LETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPA 93
+E + V VV G +LPC RG + V+W + GE P
Sbjct: 2219 VEFQNDVVVVRGSLVELPCEARG---VPLPLVSWMK--DGE-----------------PL 2256
Query: 94 YEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSL 153
+EQ P S+ L D G Y C V+ AG + +L V+ PP
Sbjct: 2257 LSQSLEQGP--------SLQLEAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPHIED 2307
Query: 154 NPGPA-LEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVP 212
+ P L G + C A+G+P P++TW + G +R +SR+ V
Sbjct: 2308 SGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD--GQALTRLENNSRATRVL------- 2358
Query: 213 SRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQN-LWHIGREGAMLKCL 271
R + TC+ P I V A ++ G + + +L+C
Sbjct: 2359 -RVRDAGLYTCLAESPA----GAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECS 2413
Query: 272 SEGQPPPSYNWTRLDGPLPSGVRVD----GDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQ 327
E +P P W R L G L L+T SG Y C N S
Sbjct: 2414 VEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVA 2473
Query: 328 VTVDV 332
V++
Sbjct: 2474 FRVEI 2478
Score = 48.5 bits (114), Expect = 1e-05
Identities = 63/238 (26%), Positives = 85/238 (35%), Gaps = 35/238 (14%)
Query: 109 DGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQ-GLTL 167
+GS+ L + AD G+YEC+ +T GS R +L V VPP + A G G +L
Sbjct: 56 EGSLFLASVSPADSGDYECQ-ATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSL 114
Query: 168 AASCTAEGSPAPSVTW--DTEVKGTT----------------SSRSFKHSRSAAVTSEFH 209
C A G P P + W D ++ G R +S
Sbjct: 115 TLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP---R 171
Query: 210 LVPSRS------MNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGL-EDQNLWHIG 262
+ P RS G T GL ++ S A SV G Q + +
Sbjct: 172 IQPGRSGRRGAQAGGSAQTKAPWXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLGLA 231
Query: 263 REGAMLKCLSEGQPPPSYNWTRLDGP-LPSG----VRVDGDTLGFPPLTTEHSGIYVC 315
L+C + G P P WT+ P LP G V+ DG L G Y C
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQC 289
Score = 47.0 bits (110), Expect = 4e-05
Identities = 58/231 (25%), Positives = 85/231 (36%), Gaps = 36/231 (15%)
Query: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP----ALEEGQGLTLAASCTAEGS 176
D G Y C + PAG+ + R+RV PP GP L GQ L C+ E
Sbjct: 2362 DAGLYTCLAES-PAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQ---LVLECSVEAE 2417
Query: 177 PAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHL-VPSRS--MNGQPLTCVVSHPGLLQD 233
PAP +TW H + + H P R + Q L+ S
Sbjct: 2418 PAPKITW--------------HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTA 2463
Query: 234 QRITHILHVSFLAEASV-----RGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTR---- 284
+ V+F E G N+ + A+L C ++G P P +W +
Sbjct: 2464 RNAAGSTSVAFRVEIHTVPTIRSGPPAVNV--SVNQTALLPCQADGVPAPLVSWRKDRVP 2521
Query: 285 LDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
LD P + +L P+ + +G Y+C SN S + VL+P
Sbjct: 2522 LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEP 2572
Score = 47.0 bits (110), Expect = 4e-05
Identities = 61/230 (26%), Positives = 87/230 (37%), Gaps = 36/230 (15%)
Query: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAP 179
AD G+Y C AGS R+ + P P PA+ T C A+G PAP
Sbjct: 2454 ADSGDYSCTARN-AAGSTSVAFRVEIHTVPTIRSGP-PAVNVSVNQTALLPCQADGVPAP 2511
Query: 180 SVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPL--------TCVVSH-PGL 230
V+W + + RS F ++P S+ QP+ C+ S+ G
Sbjct: 2512 LVSWRKD-RVPLDPRS----------PRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGS 2560
Query: 231 LQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNW----TRLD 286
+ R +L +A + NL A+L C + G P P W +LD
Sbjct: 2561 DRQGRDLRVLEPPAIAPS------PSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLD 2614
Query: 287 GPLPSGV--RVDGDTLGFPPLTTEHSGIYVCHVSNEF--SSRDSQVTVDV 332
L G + + L + S + C VSNE + R QVTV V
Sbjct: 2615 FRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHV 2664
Score = 46.6 bits (109), Expect = 5e-05
Identities = 67/299 (22%), Positives = 110/299 (36%), Gaps = 30/299 (10%)
Query: 56 GDSGEQVGQVAWARVDA-GEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLL 114
GD ++G W R A G + + ++ P EG EQ GS L
Sbjct: 2945 GDRSLRLGDRLWLRCAARGSPTPRIG-----WTVNDRPVTEGVSEQD-------GGSTLQ 2992
Query: 115 RNAV-QADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTA 173
R AV + D G Y C G QA + V P+ L E G ++ C
Sbjct: 2993 RAAVSREDSGTYVCWAEN-RVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVV 3051
Query: 174 EGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233
G P P + W +K R H R + + + C+ + +
Sbjct: 3052 RGDPVPDIHW---IKDGLPLRG-SHLRHQLQNGSLTIHRTERDDAGRYQCLAEN-----E 3102
Query: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGV 293
+ + + L A V +E Q++ + L+C + G+P P+ W + PL +
Sbjct: 3103 MGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR 3162
Query: 294 RV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVL-DPQEDSGKQVDLVS 347
R+ DG +L + T +G Y C N S ++ + V +PQ G +++
Sbjct: 3163 RLRTLPDG-SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVIN 3220
Score = 44.7 bits (104), Expect = 2e-04
Identities = 63/259 (24%), Positives = 93/259 (35%), Gaps = 34/259 (13%)
Query: 97 RVEQPPPPRNP---LDGSVLLR--NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP-L 150
R E+P P L G +L+ + D G Y C S AG + + VLVPP +
Sbjct: 1197 RGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASN-EAGEARRNFSVEVLVPPSI 1255
Query: 151 PSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHL 210
+ + ++ G T C G P P +TW FK R A H+
Sbjct: 1256 ENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTW------------FKDGRPLARGDAHHI 1303
Query: 211 VPSRSMNGQPLTCVVSHPGLLQ-------DQRITHILHVSFLAEASVRGLE---DQNLWH 260
P + Q L +S G ++ H LA + G E D+ +
Sbjct: 1304 SPDGVLL-QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTV 1362
Query: 261 IGREGAMLKCLSEGQPPPSYNWTRLDGPLPS--GVRVDGDTLGFPPLTT--EHSGIYVCH 316
L C + P P+ W + P + +++ T G L E +G Y C
Sbjct: 1363 TVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCV 1422
Query: 317 VSNEFSSRDSQVTVDVLDP 335
V+NE V+VL P
Sbjct: 1423 VTNELGEAVKNYHVEVLIP 1441
Score = 43.9 bits (102), Expect = 3e-04
Identities = 58/236 (24%), Positives = 90/236 (38%), Gaps = 25/236 (10%)
Query: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP---ALEEGQGLTLAASCTAEGSP 177
DEG Y C + AG + + L+VLVPP ++ PGP A+ E +TL C A G P
Sbjct: 668 DEGIYTCAATNL-AGESKREVALKVLVPP--NIEPGPVNKAVLENASVTL--ECLASGVP 722
Query: 178 APSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRIT 237
P V+W KG S+ + + ++ + CV S+ + R
Sbjct: 723 PPDVSW---FKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYG 779
Query: 238 HILHV--SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPL-PSG-- 292
++V S+ G N L C + G P P+ W + P+ P+G
Sbjct: 780 LRVNVPPRITLPPSLPGPVLVN------TPVRLTCNATGAPSPTLMWLKDGNPVSPAGTP 833
Query: 293 ---VRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDL 345
V G L SG Y C + V + V P G+++++
Sbjct: 834 GLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNV 889
Score = 40.8 bits (94), Expect = 0.003
Identities = 68/303 (22%), Positives = 107/303 (35%), Gaps = 53/303 (17%)
Query: 41 TVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQ 100
TV + L C +G V+W++ A GA+ G VSP+
Sbjct: 2676 TVTMMAPVVLTCH---STGIPAPTVSWSKAGAQLGARGS-------GYRVSPS------- 2718
Query: 101 PPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRV----LVPPLPSLNPG 156
G++ + A+ G Y C AG + L V +V PLPS+
Sbjct: 2719 ---------GALEIGQALPIHAGRYTCSARN-SAGVAHKHVFLTVQASPVVKPLPSVVRA 2768
Query: 157 PALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSM 216
A EE + C A G P P++TW E + S + + H P +
Sbjct: 2769 VAEEE-----VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIA-HASPEDAG 2822
Query: 217 NGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQP 276
N C+ + + ++ V + E + L H A L C + G P
Sbjct: 2823 N---YLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSH-----AFLPCKARGSP 2874
Query: 277 PPSYNWTRLDGPLPSG------VRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTV 330
P+ W + DG SG ++ G+ L L + +G Y C N +V +
Sbjct: 2875 EPNITWDK-DGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRARRRVHL 2932
Query: 331 DVL 333
+L
Sbjct: 2933 TIL 2935
Score = 40.0 bits (92), Expect = 0.005
Identities = 53/237 (22%), Positives = 81/237 (34%), Gaps = 22/237 (9%)
Query: 110 GSVLLRNAVQADE-GEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEE---GQGL 165
G VL V+A+ G Y C+ S G L VL PP+ + +EE
Sbjct: 1612 GRVLQIPLVRAENAGRYSCKASN-EVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 1670
Query: 166 TLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSE---FHLVPSRSMNGQPLT 222
T++ C A G+P P+++W + F S V + + + +
Sbjct: 1671 TVSLQCPALGNPVPTISW------LQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYM 1724
Query: 223 CVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNW 282
CV + ++ T + V + GL+ + + I L C P P W
Sbjct: 1725 CVAENQAGSAEKLFTLRVQV----PPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTW 1780
Query: 283 TRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
+ L G V TL SG+Y C N V + VL P
Sbjct: 1781 YKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 1837
Score = 35.4 bits (80), Expect = 0.12
Identities = 48/213 (22%), Positives = 71/213 (33%), Gaps = 38/213 (17%)
Query: 148 PPLPSLNPGPALEEGQGLTLA---ASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAV 204
P PS+ A +E GL A C G P P V W + R +
Sbjct: 213 PAPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKD-------------RQPVL 259
Query: 205 TSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEAS----VRGLEDQNLWH 260
HL +GQ L SH G D+ + S + + +R +W
Sbjct: 260 PGGPHLQVQE--DGQVLRITGSHVG---DEGRYQCVAFSPAGQQARDFQLRVHAPPTIWG 314
Query: 261 IGREGAM---------LKCLSEGQPPPSYNWTRLDGPLPSGVRV----DGDTLGFPPLTT 307
G + L C + G P P+ W + LP+ +V G L +
Sbjct: 315 SNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQS 374
Query: 308 EHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSG 340
+G+Y C SN + + +DV P G
Sbjct: 375 SDAGVYTCKASNAVGAAEKATRLDVYVPPTIEG 407
Score = 34.7 bits (78), Expect = 0.21
Identities = 53/224 (23%), Positives = 87/224 (38%), Gaps = 29/224 (12%)
Query: 111 SVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAAS 170
++LL D ++EC VS G ++ V VPP + + + +
Sbjct: 2629 ALLLTAPGPQDSAQFECVVSN-EVGEAHRLYQVTVHVPPTIA-DDQTDFTVTMMAPVVLT 2686
Query: 171 CTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMN-GQPLTCVVSHPG 229
C + G PAP+V+W S ++ A S + + PS ++ GQ L H G
Sbjct: 2687 CHSTGIPAPTVSW-----------SKAGAQLGARGSGYRVSPSGALEIGQALPI---HAG 2732
Query: 230 LL-----QDQRITHILHVSFLAEAS--VRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNW 282
+ H HV +AS V+ L + + E +L C + G P P+ W
Sbjct: 2733 RYTCSARNSAGVAH-KHVFLTVQASPVVKPLPSV-VRAVAEEEVLLPCEASGIPRPTITW 2790
Query: 283 TRLDGPLPSGVR---VDGDTLGFPPLTTEHSGIYVCHVSNEFSS 323
+ + +GV + G L + E +G Y+C N S
Sbjct: 2791 QKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS 2834
Score = 33.1 bits (74), Expect = 0.62
Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 268 LKCLSEGQPPPSYNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSS 323
L+C + G P P+ +W + P R+ DG L + Y+C N+ S
Sbjct: 1674 LQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGS 1733
Query: 324 RDSQVTVDVLDPQEDSGKQVDLVSA 348
+ T+ V P +G ++ V+A
Sbjct: 1734 AEKLFTLRVQVPPRIAGLDLEQVTA 1758
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 70.5 bits (171), Expect = 3e-12
Identities = 62/218 (28%), Positives = 91/218 (41%), Gaps = 24/218 (11%)
Query: 110 GSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAA 169
G + + +A D G Y C ++ AGS + RL V VPP+ N P L +G
Sbjct: 4000 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIE-NGLPDLSTTEGSHAFL 4057
Query: 170 SCTAEGSPAPSVTWDTE---VKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQ---PLTC 223
C A GSP P++TWD + V G + + S V +++ GQ TC
Sbjct: 4058 PCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLV---------KNLEGQDAGTYTC 4108
Query: 224 VVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWT 283
+ +R+ H++ L L +G + L+C + G P P WT
Sbjct: 4109 TAENAVGRARRRV----HLTILVLPVFTTLPGDRSLRLG-DRLWLRCAARGSPTPRIGWT 4163
Query: 284 RLDGPLPSGV--RVDGDTLGFPPLTTEHSGIYVCHVSN 319
D P+ GV + G TL ++ E SG YVC N
Sbjct: 4164 VNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAEN 4201
Score = 65.9 bits (159), Expect = 9e-11
Identities = 88/363 (24%), Positives = 133/363 (36%), Gaps = 91/363 (25%)
Query: 26 TGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSK 85
TG P ++ V V+ GQ LPC +G + + W +
Sbjct: 880 TGHAPPQIASSAPTVRVLEGQPVSLPCIVL--AGRPLPERHWLK---------------- 921
Query: 86 YGLHVSPAYEGRVEQPPPPRNPL--DGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRL 143
+GR PP R+ + DGS+ L A+Q G Y C V+T AGS + L
Sbjct: 922 ---------DGR-PLPPGSRHSIRADGSLHLDRALQEHAGRYSC-VATNTAGSQHRDVEL 970
Query: 144 RVLVPPLPSLNPGPALE-EGQGLTLAASCTAEGSPAPSVTWDTEVKGTT----------- 191
V VP P ++P +G+ + C A G PAP++TW E T
Sbjct: 971 VVQVP--PRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKE 1028
Query: 192 --------------------------SSRSFKHS-----RSAAVTSEFHLVPSRSM---- 216
SS+ + S S V E+ L+PS S+
Sbjct: 1029 GTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQ 1088
Query: 217 ----NGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLS 272
+ C S+P R + V + R L+ + E L C++
Sbjct: 1089 VQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLK-----VLVGEALDLNCVA 1143
Query: 273 EGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332
EG P P +W++ DG + G G ++ F + T +G Y C SN +V + V
Sbjct: 1144 EGNPEPQLSWSK-DGVVLQGRGPQG-SVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRV 1201
Query: 333 LDP 335
L+P
Sbjct: 1202 LEP 1204
Score = 65.9 bits (159), Expect = 9e-11
Identities = 69/239 (28%), Positives = 102/239 (42%), Gaps = 30/239 (12%)
Query: 108 LDGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP---LPSLNPGPALEEGQ 163
+DG VL + A +D G Y C V++ AGS + R LRV VPP LP PGP L
Sbjct: 1936 VDGRVLRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVN-- 1992
Query: 164 GLTLAASCTAEGSPAPSVTW-----DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNG 218
+ +C A G+P+P++ W GT + F R + S +R+ +
Sbjct: 1993 -TPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLAS------ARASDS 2045
Query: 219 QPLTCV-VSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPP 277
+CV VS G + R +L V S+ G E+ N+ + E L+C S PP
Sbjct: 2046 GRYSCVAVSAVG---EDRQDVVLQVHM--PPSILG-EELNVSVVANESVALECQSHAMPP 2099
Query: 278 PSYNWTRLDGPLP--SGVRVDGD--TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332
P +W + PL GV + D L +G Y C N+ + ++V
Sbjct: 2100 PVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 2158
Score = 63.9 bits (154), Expect = 3e-10
Identities = 66/242 (27%), Positives = 92/242 (38%), Gaps = 26/242 (10%)
Query: 110 GSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP-ALEEGQGLTLA 168
GS+ L D G YEC S PAGS R L V VPP + PGP L+ G L
Sbjct: 1082 GSLRLAQVQVGDSGHYECTASN-PAGSASHRYVLGVQVPP--QVQPGPRVLKVLVGEALD 1138
Query: 169 ASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228
+C AEG+P P ++W S+ + H R+ + C S+
Sbjct: 1139 LNCVAEGNPEPQLSW---------SKDGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASNS 1189
Query: 229 GLLQDQRI-THILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDG 287
+ + +L GL L + E A L C + G P P W +
Sbjct: 1190 AGVDAWEVELRVLEPPHWGADETSGL----LERVAGENASLPCPARGTPKPQVTWRKGPS 1245
Query: 288 PLP----SGVRV-DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP---QEDS 339
P GV V + +L ++ SG Y C +NE S + + V P +ED
Sbjct: 1246 SEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDG 1305
Query: 340 GK 341
K
Sbjct: 1306 RK 1307
Score = 61.6 bits (148), Expect = 2e-09
Identities = 59/225 (26%), Positives = 92/225 (40%), Gaps = 13/225 (5%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP--ALEEGQGLTLAASC 171
L A +D G Y C+ S G+ + RL V VPP G ++ G +A C
Sbjct: 1560 LGRAQSSDAGVYTCKASN-AVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALEC 1618
Query: 172 TAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLL 231
A G P+P+++W E S SR S L + +CV S P
Sbjct: 1619 VARGHPSPTLSWHHEGLPVAESNE---SRLETDGSVLRLESPGEASSGLYSCVASSPA-- 1673
Query: 232 QDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLP- 290
+ + + + V + V Q +G+ L C + G P P+ W + P
Sbjct: 1674 GEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQP-LELPCQASGSPVPTIQWLQNGRPAEE 1732
Query: 291 -SGVRV--DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332
+GV+V G TL + +HSG++ C +NE + ++V V V
Sbjct: 1733 LAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 1777
Score = 61.2 bits (147), Expect = 2e-09
Identities = 64/250 (25%), Positives = 105/250 (42%), Gaps = 20/250 (8%)
Query: 117 AVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGS 176
A +A+EG YEC + AG+ +A+ ++ V PP P L P P + G T SC G
Sbjct: 486 ASKAEEGTYEC-TAVSRAGTGRAKAQIVVTDPP-PQLVPAPNVTVSPGETAVLSCRVLGE 543
Query: 177 PAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFH-LVPSRSMNGQPLTCVVSHPGLLQDQR 235
++TW + + +S + ++ A ++ E ++P+ +G CV S+
Sbjct: 544 APYNLTWVRDWRVLPASTG-RVAQLADLSLEISGIIPT---DGGRYQCVASNA-----NG 594
Query: 236 ITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRV 295
+T + EA + + + C + G P P +W+R L R+
Sbjct: 595 VTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRI 654
Query: 296 DGD---TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVV 352
D TL + E +G Y C +NE + VT+ DP V V+A V+V
Sbjct: 655 HVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDP-----PSVSAVNAVVLV 709
Query: 353 VGVIAALLFC 362
A+L C
Sbjct: 710 AVGEEAVLVC 719
Score = 61.2 bits (147), Expect = 2e-09
Identities = 78/303 (25%), Positives = 109/303 (35%), Gaps = 49/303 (16%)
Query: 32 GELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVS 91
G ETS ++ V G++A LPC RG QV W + + E LH + G+ V
Sbjct: 1208 GADETSGLLERVAGENASLPCPARGTPKP---QVTWRKGPSSEP------LHGQPGVAVL 1258
Query: 92 PAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLP 151
+GS+ L + AD G+YEC+ +T GS R +L V VPP
Sbjct: 1259 E----------------EGSLFLASVSPADSGDYECQ-ATNEVGSTSRRAKLVVYVPPSI 1301
Query: 152 SLNPGPALEEGQ-GLTLAASCTAEGSPAPSVTW--DTEVKGTTSS----------RSFKH 198
+ A G G +L C A G P P + W D ++ G
Sbjct: 1302 REDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGG 1361
Query: 199 SRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGL-EDQN 257
R H + + +C + Q H+ L SV G Q
Sbjct: 1362 HRLLDEGQSLHFPRIQEGDSGLYSCRAEN----QAGTAQRDFHLLVLTPPSVLGAGAAQE 1417
Query: 258 LWHIGREGAMLKCLSEGQPPPSYNWTRLDGP-LPSG----VRVDGDTLGFPPLTTEHSGI 312
+ + L+C + G P P WT+ P LP G V+ DG L G
Sbjct: 1418 VLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGR 1477
Query: 313 YVC 315
Y C
Sbjct: 1478 YQC 1480
Score = 60.8 bits (146), Expect = 3e-09
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 13/228 (5%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTA 173
++ A +D+G Y C+VS AG L V VPP + + G L +C
Sbjct: 3090 IQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDV 3148
Query: 174 EGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233
G PAP+VTW + SS + V+ L SR Q T +
Sbjct: 3149 SGVPAPTVTWLKDRMPVESS-----AVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAE 3203
Query: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGV 293
R ++ V G+ ++ G+E L C ++GQPPP W + PL +
Sbjct: 3204 ARKDFVVAVLVAPRIRSSGVAREHHVLEGQE-VRLDCEADGQPPPDVAWLKDGSPLGQDM 3262
Query: 294 ------RVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
+DG +L L +G Y C N TV+VL P
Sbjct: 3263 GPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVP 3310
Score = 58.2 bits (139), Expect = 2e-08
Identities = 86/340 (25%), Positives = 123/340 (36%), Gaps = 44/340 (12%)
Query: 30 PAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGL- 88
P L S +TV G L C RG ++ + GEGA GL
Sbjct: 2162 PVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGA----------GLQ 2211
Query: 89 HVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVP 148
HVS GR+ + L A A EG Y C S S Q L+L V VP
Sbjct: 2212 HVSAV--GRL-------------LYLGQAQLAQEGTYTCECSNVVGNSSQD-LQLEVHVP 2255
Query: 149 PLPS--LNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTS 206
P + P + Q C A G P P+VTW+ + + + +
Sbjct: 2256 PQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG---Q 2312
Query: 207 EFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLED--QNLWHIGRE 264
H+ +++ + +CV + R +S L + G D N+
Sbjct: 2313 SLHVERAQAAHTGRYSCVAENLA----GRAERKFELSVLVPPELIGDLDPLTNITAALHS 2368
Query: 265 GAMLKCLSEGQPPPSYNWTRLDGPLPSG----VRVDGDTLGFPPLTTEHSGIYVCHVSNE 320
L C + G PPP+ W R + P+ G + G L + SG+Y C SNE
Sbjct: 2369 PLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNE 2428
Query: 321 FSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALL 360
+V+VL P S + DL V+ G A L+
Sbjct: 2429 AGEARRNFSVEVLVP--PSIENEDLEEVIKVLDGQTAHLM 2466
Score = 57.0 bits (136), Expect = 4e-08
Identities = 73/306 (23%), Positives = 118/306 (38%), Gaps = 42/306 (13%)
Query: 30 PAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLH 89
P +L + VTV G+ A L C G++ + W R
Sbjct: 516 PPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNL---TWVR-----------------DWR 555
Query: 90 VSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP 149
V PA GRV Q D S+ + + D G Y+C V++ G +A + L V P
Sbjct: 556 VLPASTGRVAQLA------DLSLEISGIIPTDGGRYQC-VASNANGVTRASVWLLVREAP 608
Query: 150 LPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFH 209
S++ + QG+ + SC+A G P P ++W E + S H +
Sbjct: 609 QVSIHTS-SQHFSQGVEVKVSCSASGYPTPHISWSRESQALQED-SRIHVDAQGTLIIQG 666
Query: 210 LVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLK 269
+ P + N +C ++ + +T + + SV + L +G E A+L
Sbjct: 667 VAPEDAGN---YSCQATNEVGTDQETVT----LYYTDPPSVSAVNAVVLVAVGEE-AVLV 718
Query: 270 CLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLG---FPPLTTEHSGIYVCHVSNEFSSRDS 326
C + G PPP W R G L + +G + G P +G Y C NE +
Sbjct: 719 CEASGVPPPRVIWYR--GGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASA 776
Query: 327 QVTVDV 332
++ + V
Sbjct: 777 EIQLAV 782
Score = 57.0 bits (136), Expect = 4e-08
Identities = 76/310 (24%), Positives = 120/310 (38%), Gaps = 39/310 (12%)
Query: 42 VVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQP 101
V+ GQ+ +L C G+ VAW + D Q++ G H+ +G
Sbjct: 3229 VLEGQEVRLDC---EADGQPPPDVAWLK-DGSPLGQDM-------GPHLRFYLDG----- 3272
Query: 102 PPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPL--PSLNPGPAL 159
GS++L+ +D G Y C V+ PAG + VLVPP + L
Sbjct: 3273 --------GSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTL 3323
Query: 160 EEGQGLTLAASCTAEGSPAPSVTWDTE-VKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNG 218
G + C GSP V+W + + S R+ H + + + +
Sbjct: 3324 VSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTL----RISKVQLADA 3379
Query: 219 QPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAM-LKCLSEGQPP 277
TCV + P + D+ T + V + E +E QN + R + L C + G P
Sbjct: 3380 GIFTCVAASPAGVADRNFTLQVQVPPVLEP----VEFQNDVVVVRGSLVELPCEARGVPL 3435
Query: 278 PSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQ- 336
P +W + PL S G +L + SG Y C +E + V++P
Sbjct: 3436 PLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 3495
Query: 337 -EDSGKQVDL 345
EDSG+ +L
Sbjct: 3496 IEDSGQPTEL 3505
Score = 56.6 bits (135), Expect = 5e-08
Identities = 66/262 (25%), Positives = 95/262 (36%), Gaps = 31/262 (11%)
Query: 116 NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQ-------GLTLA 168
NA + D G+Y C V T G + VL+PP S + P E G TL
Sbjct: 2601 NAQKEDAGQYTC-VVTNELGEAVKNYHVEVLIPPSISKDD-PLGEVGVKEVKTKVNSTLT 2658
Query: 169 ASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228
C + P P++ W + + T S + + + P++ + CV ++
Sbjct: 2659 LECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL---LQIQPTQVSDSGRYLCVATNV 2715
Query: 229 GLLQDQRITHILHV--------SFLA-------EASVRGLEDQNLWHIGREGAMLKCLSE 273
DQ ++ V F A E RG + + A L C +
Sbjct: 2716 AGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTN 2775
Query: 274 GQPPPSYNWTRLDGPLPSGVRVD----GDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVT 329
PPP W R D PL +G V G L P + E++G Y C SNE
Sbjct: 2776 AIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYE 2835
Query: 330 VDVLDPQEDSGKQVDLVSASVV 351
+ VL P G +LV V
Sbjct: 2836 LLVLTPPVILGDTEELVEEVTV 2857
Score = 56.2 bits (134), Expect = 7e-08
Identities = 78/306 (25%), Positives = 115/306 (37%), Gaps = 46/306 (15%)
Query: 40 VTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVE 99
VTV LG+ A L C +G V W R D GL + R
Sbjct: 795 VTVELGRSALLAC---RATGRPPPTVTWRRGDG-----------QPLGLRLGAGRGSRSR 840
Query: 100 QPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVL---VPPLPSLNPG 156
QP G + + D+ Y C G QA RL V P + S P
Sbjct: 841 QPD------SGVLFFESVAPEDQAPYVCEARNV-FGKVQAEARLIVTGHAPPQIASSAPT 893
Query: 157 PALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSM 216
+ EGQ ++L A G P P W + G +HS A HL +
Sbjct: 894 VRVLEGQPVSLPCIVLA-GRPLPERHWLKD--GRPLPPGSRHSIRA--DGSLHLDRALQE 948
Query: 217 NGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREG--AMLKCLSEG 274
+ +CV ++ Q + + ++ V + HI EG A L C++ G
Sbjct: 949 HAGRYSCVATNTAGSQHRDVELVVQVP-------PRIHPTATHHITNEGVPASLPCVASG 1001
Query: 275 QPPPSYNWTRLDGPLPS-----GVRVDGDTLGFPPLTTEHSGIYVCHVSNE--FSSRDSQ 327
P P+ WT+ L S V +G L P + + +G YVC +N FSS++ +
Sbjct: 1002 VPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQP-SAQDAGAYVCTATNTVGFSSQEMR 1060
Query: 328 VTVDVL 333
++V+ L
Sbjct: 1061 LSVNRL 1066
Score = 55.5 bits (132), Expect = 1e-07
Identities = 67/265 (25%), Positives = 102/265 (38%), Gaps = 36/265 (13%)
Query: 102 PPPRNPL--DGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPA 158
P PR + DG VL + A AD Y C V+ AGS + LRV VPP + G
Sbjct: 2888 PSPRLQVLEDGQVLQVSTAEVADAASYMC-VAENQAGSAEKLFTLRVQVPPRIA---GLD 2943
Query: 159 LEEGQGL---TLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVP--- 212
LE+ + +++ C P P VTW +K S++ ++ E L+P
Sbjct: 2944 LEQVTAILNSSVSLPCDVHAHPNPEVTW------------YKDSQALSLGEEVFLLPGTH 2991
Query: 213 ------SRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGA 266
+R + TC + + + + V + RG +D L +G + A
Sbjct: 2992 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVG-DKA 3050
Query: 267 MLKCLSEGQPPPSYNWTRLDGPLPSGVRVD----GDTLGFPPLTTEHSGIYVCHVSNEFS 322
+L C ++ P P+ W + PL R G L G+Y C VSN
Sbjct: 3051 VLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAG 3110
Query: 323 SRDSQVTVDVLDPQEDSGKQVDLVS 347
T+ V P + + VS
Sbjct: 3111 EAVRTFTLTVQVPPTFENPKTETVS 3135
Score = 54.3 bits (129), Expect = 3e-07
Identities = 56/235 (23%), Positives = 95/235 (40%), Gaps = 12/235 (5%)
Query: 109 DGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP-LPSLNPGPALEEGQGLT 166
DG VL + + DEG Y+C V+ PAG +LRV PP + N + +
Sbjct: 1461 DGQVLRITGSHVGDEGRYQC-VAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHL 1519
Query: 167 LAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVS 226
+ C A G P P++TW + +S ++R + L ++S + TC S
Sbjct: 1520 VQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGG---RQLQLGRAQSSDAGVYTCKAS 1576
Query: 227 HPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLD 286
+ ++ ++V E + G + + L+C++ G P P+ +W
Sbjct: 1577 NAVGAAEKATRLDVYVPPTIEGA--GGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEG 1634
Query: 287 GPL----PSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQE 337
P+ S + DG L SG+Y C S+ Q +V+V P +
Sbjct: 1635 LPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQ 1689
Score = 49.7 bits (117), Expect = 6e-06
Identities = 60/252 (23%), Positives = 97/252 (38%), Gaps = 16/252 (6%)
Query: 95 EGRVEQPPPPRNPLDGSVLLR--NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPS 152
+GR +P P + LL+ A D G Y C AG + L V V P+
Sbjct: 2107 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALN-QAGHSEKHYNLNVWVAPVFP 2165
Query: 153 LNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTT-SSRSFKHSRSAAVTSEFHLV 211
L L +G + SC G P P ++W + + +H +AV +L
Sbjct: 2166 LRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQH--VSAVGRLLYLG 2223
Query: 212 PSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRG-LEDQNLWHIGREG-AMLK 269
++ TC S+ Q + +HV + G E + ++G A L+
Sbjct: 2224 QAQLAQEGTYTCECSNVVGNSSQDLQLEVHV----PPQIAGPREPPTQVSVVQDGVATLE 2279
Query: 270 CLSEGQPPPSYNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRD 325
C + G+PPP+ W R P+ + + + G +L H+G Y C N +
Sbjct: 2280 CNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 2339
Query: 326 SQVTVDVLDPQE 337
+ + VL P E
Sbjct: 2340 RKFELSVLVPPE 2351
Score = 48.9 bits (115), Expect = 1e-05
Identities = 73/305 (23%), Positives = 107/305 (35%), Gaps = 51/305 (16%)
Query: 34 LETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPA 93
+E + V VV G +LPC RG + V+W + GE P
Sbjct: 3410 VEFQNDVVVVRGSLVELPCEARG---VPLPLVSWMK--DGE-----------------PL 3447
Query: 94 YEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSL 153
+EQ P S+ L D G Y C V+ AG + +L V+ PP
Sbjct: 3448 LSQSLEQGP--------SLQLEAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPHIED 3498
Query: 154 NPGPA-LEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVP 212
+ P L G + C A+G+P P++TW + G +R +SR+ V
Sbjct: 3499 SGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD--GQALTRLENNSRATRVL------- 3549
Query: 213 SRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQN-LWHIGREGAMLKCL 271
R + TC+ P I V A ++ G + + +L+C
Sbjct: 3550 -RVRDAGLYTCLAESPA----GAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECS 3604
Query: 272 SEGQPPPSYNWTRLDGPLPSGVRVD----GDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQ 327
E +P P W R L G L L+T SG Y C N S
Sbjct: 3605 VEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVA 3664
Query: 328 VTVDV 332
V++
Sbjct: 3665 FRVEI 3669
Score = 47.4 bits (111), Expect = 3e-05
Identities = 59/242 (24%), Positives = 84/242 (34%), Gaps = 41/242 (16%)
Query: 119 QADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLA---ASCTAEG 175
+ D G Y CR AG+ Q L VL PP S+ A +E GL A C G
Sbjct: 1378 EGDSGLYSCRAEN-QAGTAQRDFHLLVLTPP--SVLGAGAAQEVLGLAGADVELQCWTSG 1434
Query: 176 SPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQR 235
P P V W + R + HL +GQ L SH G D+
Sbjct: 1435 VPTPQVEWTKD-------------RQPVLPGGPHLQVQE--DGQVLRITGSHVG---DEG 1476
Query: 236 ITHILHVSFLAEAS----VRGLEDQNLWHIGREGAM---------LKCLSEGQPPPSYNW 282
+ S + + +R +W G + L C + G P P+ W
Sbjct: 1477 RYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITW 1536
Query: 283 TRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQED 338
+ LP+ +V G L + +G+Y C SN + + +DV P
Sbjct: 1537 FKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTI 1596
Query: 339 SG 340
G
Sbjct: 1597 EG 1598
Score = 47.0 bits (110), Expect = 4e-05
Identities = 58/231 (25%), Positives = 85/231 (36%), Gaps = 36/231 (15%)
Query: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP----ALEEGQGLTLAASCTAEGS 176
D G Y C + PAG+ + R+RV PP GP L GQ L C+ E
Sbjct: 3553 DAGLYTCLAES-PAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQ---LVLECSVEAE 3608
Query: 177 PAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHL-VPSRS--MNGQPLTCVVSHPGLLQD 233
PAP +TW H + + H P R + Q L+ S
Sbjct: 3609 PAPKITW--------------HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTA 3654
Query: 234 QRITHILHVSFLAEASV-----RGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTR---- 284
+ V+F E G N+ + A+L C ++G P P +W +
Sbjct: 3655 RNAAGSTSVAFRVEIHTVPTIRSGPPAVNV--SVNQTALLPCQADGVPAPLVSWRKDRVP 3712
Query: 285 LDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
LD P + +L P+ + +G Y+C SN S + VL+P
Sbjct: 3713 LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEP 3763
Score = 47.0 bits (110), Expect = 4e-05
Identities = 61/230 (26%), Positives = 87/230 (37%), Gaps = 36/230 (15%)
Query: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAP 179
AD G+Y C AGS R+ + P P PA+ T C A+G PAP
Sbjct: 3645 ADSGDYSCTARN-AAGSTSVAFRVEIHTVPTIRSGP-PAVNVSVNQTALLPCQADGVPAP 3702
Query: 180 SVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPL--------TCVVSH-PGL 230
V+W + + RS F ++P S+ QP+ C+ S+ G
Sbjct: 3703 LVSWRKD-RVPLDPRS----------PRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGS 3751
Query: 231 LQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNW----TRLD 286
+ R +L +A + NL A+L C + G P P W +LD
Sbjct: 3752 DRQGRDLRVLEPPAIAPS------PSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLD 3805
Query: 287 GPLPSGV--RVDGDTLGFPPLTTEHSGIYVCHVSNEF--SSRDSQVTVDV 332
L G + + L + S + C VSNE + R QVTV V
Sbjct: 3806 FRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHV 3855
Score = 46.6 bits (109), Expect = 5e-05
Identities = 62/253 (24%), Positives = 90/253 (35%), Gaps = 40/253 (15%)
Query: 110 GSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPAL-EEGQGLTLA 168
GSV +D G Y C S AG + LRVL PP + L E G +
Sbjct: 1167 GSVHFAAIRTSDAGRYRCEASN-SAGVDAWEVELRVLEPPHWGADETSGLLERVAGENAS 1225
Query: 169 ASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSE--FHLVPSRSMNGQPLTCVVS 226
C A G+P P VTW + SS AV E L + C +
Sbjct: 1226 LPCPARGTPKPQVTW----RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQAT 1281
Query: 227 HPGLLQDQRITHILHV-----SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYN 281
+ +R +++V +A+V G+ Q+L L+C + G P P
Sbjct: 1282 NEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSL--------TLECDANGFPVPEIV 1333
Query: 282 WTR-----------------LDGPLPSGVRV--DGDTLGFPPLTTEHSGIYVCHVSNEFS 322
W + L G R+ +G +L FP + SG+Y C N+
Sbjct: 1334 WLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAG 1393
Query: 323 SRDSQVTVDVLDP 335
+ + VL P
Sbjct: 1394 TAQRDFHLLVLTP 1406
Score = 46.6 bits (109), Expect = 5e-05
Identities = 67/299 (22%), Positives = 110/299 (36%), Gaps = 30/299 (10%)
Query: 56 GDSGEQVGQVAWARVDA-GEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLL 114
GD ++G W R A G + + ++ P EG EQ GS L
Sbjct: 4136 GDRSLRLGDRLWLRCAARGSPTPRIG-----WTVNDRPVTEGVSEQD-------GGSTLQ 4183
Query: 115 RNAV-QADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTA 173
R AV + D G Y C G QA + V P+ L E G ++ C
Sbjct: 4184 RAAVSREDSGTYVCWAEN-RVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVV 4242
Query: 174 EGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233
G P P + W +K R H R + + + C+ + +
Sbjct: 4243 RGDPVPDIHW---IKDGLPLRG-SHLRHQLQNGSLTIHRTERDDAGRYQCLAEN-----E 4293
Query: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGV 293
+ + + L A V +E Q++ + L+C + G+P P+ W + PL +
Sbjct: 4294 MGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR 4353
Query: 294 RV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVL-DPQEDSGKQVDLVS 347
R+ DG +L + T +G Y C N S ++ + V +PQ G +++
Sbjct: 4354 RLRTLPDG-SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVIN 4411
Score = 44.7 bits (104), Expect = 2e-04
Identities = 63/259 (24%), Positives = 93/259 (35%), Gaps = 34/259 (13%)
Query: 97 RVEQPPPPRNP---LDGSVLLR--NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP-L 150
R E+P P L G +L+ + D G Y C S AG + + VLVPP +
Sbjct: 2388 RGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASN-EAGEARRNFSVEVLVPPSI 2446
Query: 151 PSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHL 210
+ + ++ G T C G P P +TW FK R A H+
Sbjct: 2447 ENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTW------------FKDGRPLARGDAHHI 2494
Query: 211 VPSRSMNGQPLTCVVSHPGLLQ-------DQRITHILHVSFLAEASVRGLE---DQNLWH 260
P + Q L +S G ++ H LA + G E D+ +
Sbjct: 2495 SPDGVLL-QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTV 2553
Query: 261 IGREGAMLKCLSEGQPPPSYNWTRLDGPLPS--GVRVDGDTLGFPPLTT--EHSGIYVCH 316
L C + P P+ W + P + +++ T G L E +G Y C
Sbjct: 2554 TVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCV 2613
Query: 317 VSNEFSSRDSQVTVDVLDP 335
V+NE V+VL P
Sbjct: 2614 VTNELGEAVKNYHVEVLIP 2632
Score = 43.9 bits (102), Expect = 3e-04
Identities = 58/236 (24%), Positives = 90/236 (38%), Gaps = 25/236 (10%)
Query: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP---ALEEGQGLTLAASCTAEGSP 177
DEG Y C + AG + + L+VLVPP ++ PGP A+ E +TL C A G P
Sbjct: 1859 DEGIYTCAATNL-AGESKREVALKVLVPP--NIEPGPVNKAVLENASVTL--ECLASGVP 1913
Query: 178 APSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRIT 237
P V+W KG S+ + + ++ + CV S+ + R
Sbjct: 1914 PPDVSW---FKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYG 1970
Query: 238 HILHV--SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPL-PSG-- 292
++V S+ G N L C + G P P+ W + P+ P+G
Sbjct: 1971 LRVNVPPRITLPPSLPGPVLVN------TPVRLTCNATGAPSPTLMWLKDGNPVSPAGTP 2024
Query: 293 ---VRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDL 345
V G L SG Y C + V + V P G+++++
Sbjct: 2025 GLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNV 2080
Score = 40.8 bits (94), Expect = 0.003
Identities = 68/303 (22%), Positives = 107/303 (35%), Gaps = 53/303 (17%)
Query: 41 TVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQ 100
TV + L C +G V+W++ A GA+ G VSP+
Sbjct: 3867 TVTMMAPVVLTCH---STGIPAPTVSWSKAGAQLGARGS-------GYRVSPS------- 3909
Query: 101 PPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRV----LVPPLPSLNPG 156
G++ + A+ G Y C AG + L V +V PLPS+
Sbjct: 3910 ---------GALEIGQALPIHAGRYTCSARN-SAGVAHKHVFLTVQASPVVKPLPSVVRA 3959
Query: 157 PALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSM 216
A EE + C A G P P++TW E + S + + H P +
Sbjct: 3960 VAEEE-----VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIA-HASPEDAG 4013
Query: 217 NGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQP 276
N C+ + + ++ V + E + L H A L C + G P
Sbjct: 4014 N---YLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSH-----AFLPCKARGSP 4065
Query: 277 PPSYNWTRLDGPLPSG------VRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTV 330
P+ W + DG SG ++ G+ L L + +G Y C N +V +
Sbjct: 4066 EPNITWDK-DGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRARRRVHL 4123
Query: 331 DVL 333
+L
Sbjct: 4124 TIL 4126
Score = 40.0 bits (92), Expect = 0.005
Identities = 53/237 (22%), Positives = 81/237 (34%), Gaps = 22/237 (9%)
Query: 110 GSVLLRNAVQADE-GEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEE---GQGL 165
G VL V+A+ G Y C+ S G L VL PP+ + +EE
Sbjct: 2803 GRVLQIPLVRAENAGRYSCKASN-EVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 2861
Query: 166 TLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSE---FHLVPSRSMNGQPLT 222
T++ C A G+P P+++W + F S V + + + +
Sbjct: 2862 TVSLQCPALGNPVPTISW------LQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYM 2915
Query: 223 CVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNW 282
CV + ++ T + V + GL+ + + I L C P P W
Sbjct: 2916 CVAENQAGSAEKLFTLRVQV----PPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTW 2971
Query: 283 TRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
+ L G V TL SG+Y C N V + VL P
Sbjct: 2972 YKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 3028
Score = 34.7 bits (78), Expect = 0.21
Identities = 53/224 (23%), Positives = 87/224 (38%), Gaps = 29/224 (12%)
Query: 111 SVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAAS 170
++LL D ++EC VS G ++ V VPP + + + +
Sbjct: 3820 ALLLTAPGPQDSAQFECVVSN-EVGEAHRLYQVTVHVPPTIA-DDQTDFTVTMMAPVVLT 3877
Query: 171 CTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMN-GQPLTCVVSHPG 229
C + G PAP+V+W S ++ A S + + PS ++ GQ L H G
Sbjct: 3878 CHSTGIPAPTVSW-----------SKAGAQLGARGSGYRVSPSGALEIGQALPI---HAG 3923
Query: 230 LL-----QDQRITHILHVSFLAEAS--VRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNW 282
+ H HV +AS V+ L + + E +L C + G P P+ W
Sbjct: 3924 RYTCSARNSAGVAH-KHVFLTVQASPVVKPLPSV-VRAVAEEEVLLPCEASGIPRPTITW 3981
Query: 283 TRLDGPLPSGVR---VDGDTLGFPPLTTEHSGIYVCHVSNEFSS 323
+ + +GV + G L + E +G Y+C N S
Sbjct: 3982 QKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS 4025
Score = 33.1 bits (74), Expect = 0.62
Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 268 LKCLSEGQPPPSYNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSS 323
L+C + G P P+ +W + P R+ DG L + Y+C N+ S
Sbjct: 2865 LQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGS 2924
Query: 324 RDSQVTVDVLDPQEDSGKQVDLVSA 348
+ T+ V P +G ++ V+A
Sbjct: 2925 AEKLFTLRVQVPPRIAGLDLEQVTA 2949
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 70.5 bits (171), Expect = 3e-12
Identities = 62/218 (28%), Positives = 91/218 (41%), Gaps = 24/218 (11%)
Query: 110 GSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAA 169
G + + +A D G Y C ++ AGS + RL V VPP+ N P L +G
Sbjct: 2718 GQLRIAHASPEDAGNYLC-IAKNSAGSAMGKTRLVVQVPPVIE-NGLPDLSTTEGSHAFL 2775
Query: 170 SCTAEGSPAPSVTWDTE---VKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQ---PLTC 223
C A GSP P++TWD + V G + + S V +++ GQ TC
Sbjct: 2776 PCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLV---------KNLEGQDAGTYTC 2826
Query: 224 VVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWT 283
+ +R+ H++ L L +G + L+C + G P P WT
Sbjct: 2827 TAENAVGRARRRV----HLTILVLPVFTTLPGDRSLRLG-DRLWLRCAARGSPTPRIGWT 2881
Query: 284 RLDGPLPSGV--RVDGDTLGFPPLTTEHSGIYVCHVSN 319
D P+ GV + G TL ++ E SG YVC N
Sbjct: 2882 VNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAEN 2919
Score = 65.9 bits (159), Expect = 9e-11
Identities = 69/239 (28%), Positives = 102/239 (42%), Gaps = 30/239 (12%)
Query: 108 LDGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP---LPSLNPGPALEEGQ 163
+DG VL + A +D G Y C V++ AGS + R LRV VPP LP PGP L
Sbjct: 654 VDGRVLRIEQAQLSDAGSYRC-VASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVN-- 710
Query: 164 GLTLAASCTAEGSPAPSVTW-----DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNG 218
+ +C A G+P+P++ W GT + F R + S +R+ +
Sbjct: 711 -TPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLAS------ARASDS 763
Query: 219 QPLTCV-VSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPP 277
+CV VS G + R +L V S+ G E+ N+ + E L+C S PP
Sbjct: 764 GRYSCVAVSAVG---EDRQDVVLQVHM--PPSILG-EELNVSVVANESVALECQSHAMPP 817
Query: 278 PSYNWTRLDGPLP--SGVRVDGD--TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332
P +W + PL GV + D L +G Y C N+ + ++V
Sbjct: 818 PVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNV 876
Score = 61.6 bits (148), Expect = 2e-09
Identities = 59/225 (26%), Positives = 92/225 (40%), Gaps = 13/225 (5%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP--ALEEGQGLTLAASC 171
L A +D G Y C+ S G+ + RL V VPP G ++ G +A C
Sbjct: 278 LGRAQSSDAGVYTCKASN-AVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALEC 336
Query: 172 TAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLL 231
A G P+P+++W E S SR S L + +CV S P
Sbjct: 337 VARGHPSPTLSWHHEGLPVAESNE---SRLETDGSVLRLESPGEASSGLYSCVASSPA-- 391
Query: 232 QDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLP- 290
+ + + + V + V Q +G+ L C + G P P+ W + P
Sbjct: 392 GEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQP-LELPCQASGSPVPTIQWLQNGRPAEE 450
Query: 291 -SGVRV--DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332
+GV+V G TL + +HSG++ C +NE + ++V V V
Sbjct: 451 LAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 495
Score = 60.8 bits (146), Expect = 3e-09
Identities = 60/228 (26%), Positives = 87/228 (38%), Gaps = 13/228 (5%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTA 173
++ A +D+G Y C+VS AG L V VPP + + G L +C
Sbjct: 1808 IQEAQVSDKGLYSCKVSNV-AGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDV 1866
Query: 174 EGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233
G PAP+VTW + SS + V+ L SR Q T +
Sbjct: 1867 SGVPAPTVTWLKDRMPVESS-----AVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAE 1921
Query: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGV 293
R ++ V G+ ++ G+E L C ++GQPPP W + PL +
Sbjct: 1922 ARKDFVVAVLVAPRIRSSGVAREHHVLEGQE-VRLDCEADGQPPPDVAWLKDGSPLGQDM 1980
Query: 294 ------RVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
+DG +L L +G Y C N TV+VL P
Sbjct: 1981 GPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVP 2028
Score = 58.9 bits (141), Expect = 1e-08
Identities = 86/340 (25%), Positives = 124/340 (36%), Gaps = 44/340 (12%)
Query: 30 PAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGL- 88
P L S +TV G +L C RG ++ + GEGA GL
Sbjct: 880 PVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGA----------GLQ 929
Query: 89 HVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVP 148
HVS GR+ + L A A EG Y C S S Q L+L V VP
Sbjct: 930 HVSAV--GRL-------------LYLGQAQLAQEGTYTCECSNVVGNSSQD-LQLEVHVP 973
Query: 149 PLPS--LNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTS 206
P + P + Q C A G P P+VTW+ + + + +
Sbjct: 974 PQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG---Q 1030
Query: 207 EFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLED--QNLWHIGRE 264
H+ +++ + +CV + R +S L + G D N+
Sbjct: 1031 SLHVERAQAAHTGRYSCVAENLA----GRAERKFELSVLVPPELIGDLDPLTNITAALHS 1086
Query: 265 GAMLKCLSEGQPPPSYNWTRLDGPLPSG----VRVDGDTLGFPPLTTEHSGIYVCHVSNE 320
L C + G PPP+ W R + P+ G + G L + SG+Y C SNE
Sbjct: 1087 PLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNE 1146
Query: 321 FSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALL 360
+V+VL P S + DL V+ G A L+
Sbjct: 1147 AGEARRNFSVEVLVP--PSIENEDLEEVIKVLDGQTAHLM 1184
Score = 57.8 bits (138), Expect = 2e-08
Identities = 66/262 (25%), Positives = 95/262 (36%), Gaps = 31/262 (11%)
Query: 116 NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQ-------GLTLA 168
NA + D G+Y C V T G + VL+PP S + P E G TL
Sbjct: 1319 NAQKEDAGQYTC-VVTNELGEAVKNYHVEVLIPPSISKDD-PLAEVGVKEVKTKVNSTLT 1376
Query: 169 ASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228
C + P P++ W + + T S + + + P++ + CV ++
Sbjct: 1377 LECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL---LQIQPTQVSDSGRYLCVATNV 1433
Query: 229 GLLQDQRITHILHV--------SFLA-------EASVRGLEDQNLWHIGREGAMLKCLSE 273
DQ ++ V F A E RG + + A L C +
Sbjct: 1434 AGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTN 1493
Query: 274 GQPPPSYNWTRLDGPLPSGVRVD----GDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVT 329
PPP W R D PL +G V G L P + E++G Y C SNE
Sbjct: 1494 AIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYE 1553
Query: 330 VDVLDPQEDSGKQVDLVSASVV 351
+ VL P G +LV V
Sbjct: 1554 LLVLTPPVILGDTEELVEEVTV 1575
Score = 57.0 bits (136), Expect = 4e-08
Identities = 76/310 (24%), Positives = 120/310 (38%), Gaps = 39/310 (12%)
Query: 42 VVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQP 101
V+ GQ+ +L C G+ VAW + D Q++ G H+ +G
Sbjct: 1947 VLEGQEVRLDC---EADGQPPPDVAWLK-DGSPLGQDM-------GPHLRFYLDG----- 1990
Query: 102 PPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPL--PSLNPGPAL 159
GS++L+ +D G Y C V+ PAG + VLVPP + L
Sbjct: 1991 --------GSLVLKGLRASDAGAYTC-VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTL 2041
Query: 160 EEGQGLTLAASCTAEGSPAPSVTWDTE-VKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNG 218
G + C GSP V+W + + S R+ H + + + +
Sbjct: 2042 VSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTL----RISKVQLADA 2097
Query: 219 QPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAM-LKCLSEGQPP 277
TCV + P + D+ T + V + E +E QN + R + L C + G P
Sbjct: 2098 GIFTCVAASPAGVADRNFTLQVQVPPVLEP----VEFQNDVVVVRGSLVELPCEARGVPL 2153
Query: 278 PSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQ- 336
P +W + PL S G +L + SG Y C +E + V++P
Sbjct: 2154 PLVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 2213
Query: 337 -EDSGKQVDL 345
EDSG+ +L
Sbjct: 2214 IEDSGQPTEL 2223
Score = 55.5 bits (132), Expect = 1e-07
Identities = 67/265 (25%), Positives = 102/265 (38%), Gaps = 36/265 (13%)
Query: 102 PPPRNPL--DGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPA 158
P PR + DG VL + A AD Y C V+ AGS + LRV VPP + G
Sbjct: 1606 PSPRLQVLEDGQVLQVSTAEVADAASYMC-VAENQAGSAEKLFTLRVQVPPRIA---GLD 1661
Query: 159 LEEGQGL---TLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVP--- 212
LE+ + +++ C P P VTW +K S++ ++ E L+P
Sbjct: 1662 LEQVTAILNSSVSLPCDVHAHPNPEVTW------------YKDSQALSLGEEVFLLPGTH 1709
Query: 213 ------SRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGA 266
+R + TC + + + + V + RG +D L +G + A
Sbjct: 1710 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVG-DKA 1768
Query: 267 MLKCLSEGQPPPSYNWTRLDGPLPSGVRVD----GDTLGFPPLTTEHSGIYVCHVSNEFS 322
+L C ++ P P+ W + PL R G L G+Y C VSN
Sbjct: 1769 VLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAG 1828
Query: 323 SRDSQVTVDVLDPQEDSGKQVDLVS 347
T+ V P + + VS
Sbjct: 1829 EAVRTFTLTVQVPPTFENPKTETVS 1853
Score = 54.3 bits (129), Expect = 3e-07
Identities = 56/235 (23%), Positives = 95/235 (40%), Gaps = 12/235 (5%)
Query: 109 DGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP-LPSLNPGPALEEGQGLT 166
DG VL + + DEG Y+C V+ PAG +LRV PP + N + +
Sbjct: 179 DGQVLRITGSHVGDEGRYQC-VAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHL 237
Query: 167 LAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVS 226
+ C A G P P++TW + +S ++R + L ++S + TC S
Sbjct: 238 VQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGG---RQLQLGRAQSSDAGVYTCKAS 294
Query: 227 HPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLD 286
+ ++ ++V E + G + + L+C++ G P P+ +W
Sbjct: 295 NAVGAAEKATRLDVYVPPTIEGA--GGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEG 352
Query: 287 GPL----PSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQE 337
P+ S + DG L SG+Y C S+ Q +V+V P +
Sbjct: 353 LPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPPQ 407
Score = 48.9 bits (115), Expect = 1e-05
Identities = 60/252 (23%), Positives = 96/252 (38%), Gaps = 16/252 (6%)
Query: 95 EGRVEQPPPPRNPLDGSVLLR--NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPS 152
+GR +P P + LL+ A D G Y C AG + L V V P+
Sbjct: 825 DGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALN-QAGHSEKHYNLNVWVAPVFP 883
Query: 153 LNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTT-SSRSFKHSRSAAVTSEFHLV 211
L L +G SC G P P ++W + + +H +AV +L
Sbjct: 884 LRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQH--VSAVGRLLYLG 941
Query: 212 PSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRG-LEDQNLWHIGREG-AMLK 269
++ TC S+ Q + +HV + G E + ++G A L+
Sbjct: 942 QAQLAQEGTYTCECSNVVGNSSQDLQLEVHV----PPQIAGPREPPTQVSVVQDGVATLE 997
Query: 270 CLSEGQPPPSYNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRD 325
C + G+PPP+ W R P+ + + + G +L H+G Y C N +
Sbjct: 998 CNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 1057
Query: 326 SQVTVDVLDPQE 337
+ + VL P E
Sbjct: 1058 RKFELSVLVPPE 1069
Score = 48.9 bits (115), Expect = 1e-05
Identities = 73/305 (23%), Positives = 107/305 (35%), Gaps = 51/305 (16%)
Query: 34 LETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPA 93
+E + V VV G +LPC RG + V+W + GE P
Sbjct: 2128 VEFQNDVVVVRGSLVELPCEARG---VPLPLVSWMK--DGE-----------------PL 2165
Query: 94 YEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSL 153
+EQ P S+ L D G Y C V+ AG + +L V+ PP
Sbjct: 2166 LSQSLEQGP--------SLQLEAVGAGDSGTYSC-VAVSEAGEARRHFQLTVMEPPHIED 2216
Query: 154 NPGPA-LEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVP 212
+ P L G + C A+G+P P++TW + G +R +SR+ V
Sbjct: 2217 SGQPTELSLTPGAPMELLCDAQGTPQPNITWHKD--GQALTRLENNSRATRVL------- 2267
Query: 213 SRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQN-LWHIGREGAMLKCL 271
R + TC+ P I V A ++ G + + +L+C
Sbjct: 2268 -RVRDAGLYTCLAESPA----GAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECS 2322
Query: 272 SEGQPPPSYNWTRLDGPLPSGVRVD----GDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQ 327
E +P P W R L G L L+T SG Y C N S
Sbjct: 2323 VEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVA 2382
Query: 328 VTVDV 332
V++
Sbjct: 2383 FRVEI 2387
Score = 47.4 bits (111), Expect = 3e-05
Identities = 59/241 (24%), Positives = 82/241 (34%), Gaps = 39/241 (16%)
Query: 119 QADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLA---ASCTAEG 175
+ D G Y CR AG+ Q L VL PP S+ A +E GL A C G
Sbjct: 96 EGDSGLYSCRAEN-QAGTAQRDFHLLVLTPP--SVLGAGAAQEVLGLAGADVELQCWTSG 152
Query: 176 SPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQR 235
P P V W + R + HL +GQ L SH G + R
Sbjct: 153 VPTPQVEWTKD-------------RQPVLPGGPHLQVQE--DGQVLRITGSHVG--DEGR 195
Query: 236 ITHILHVSFLAEA---SVRGLEDQNLWHIGREG---------AMLKCLSEGQPPPSYNWT 283
+ +A +R +W G L C + G P P+ W
Sbjct: 196 YQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWF 255
Query: 284 RLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDS 339
+ LP+ +V G L + +G+Y C SN + + +DV P
Sbjct: 256 KDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIE 315
Query: 340 G 340
G
Sbjct: 316 G 316
Score = 47.0 bits (110), Expect = 4e-05
Identities = 58/231 (25%), Positives = 85/231 (36%), Gaps = 36/231 (15%)
Query: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP----ALEEGQGLTLAASCTAEGS 176
D G Y C + PAG+ + R+RV PP GP L GQ L C+ E
Sbjct: 2271 DAGLYTCLAES-PAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQ---LVLECSVEAE 2326
Query: 177 PAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHL-VPSRS--MNGQPLTCVVSHPGLLQD 233
PAP +TW H + + H P R + Q L+ S
Sbjct: 2327 PAPKITW--------------HRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTA 2372
Query: 234 QRITHILHVSFLAEASV-----RGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTR---- 284
+ V+F E G N+ + A+L C ++G P P +W +
Sbjct: 2373 RNAAGSTSVAFRVEIHTVPTIRSGPPAVNV--SVNQTALLPCQADGVPAPLVSWRKDRVP 2430
Query: 285 LDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
LD P + +L P+ + +G Y+C SN S + VL+P
Sbjct: 2431 LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEP 2481
Score = 47.0 bits (110), Expect = 4e-05
Identities = 61/230 (26%), Positives = 87/230 (37%), Gaps = 36/230 (15%)
Query: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAP 179
AD G+Y C AGS R+ + P P PA+ T C A+G PAP
Sbjct: 2363 ADSGDYSCTARN-AAGSTSVAFRVEIHTVPTIRSGP-PAVNVSVNQTALLPCQADGVPAP 2420
Query: 180 SVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPL--------TCVVSH-PGL 230
V+W + + RS F ++P S+ QP+ C+ S+ G
Sbjct: 2421 LVSWRKD-RVPLDPRS----------PRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGS 2469
Query: 231 LQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNW----TRLD 286
+ R +L +A + NL A+L C + G P P W +LD
Sbjct: 2470 DRQGRDLRVLEPPAIAPS------PSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLD 2523
Query: 287 GPLPSGV--RVDGDTLGFPPLTTEHSGIYVCHVSNEF--SSRDSQVTVDV 332
L G + + L + S + C VSNE + R QVTV V
Sbjct: 2524 FRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHV 2573
Score = 46.6 bits (109), Expect = 5e-05
Identities = 67/299 (22%), Positives = 110/299 (36%), Gaps = 30/299 (10%)
Query: 56 GDSGEQVGQVAWARVDA-GEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLL 114
GD ++G W R A G + + ++ P EG EQ GS L
Sbjct: 2854 GDRSLRLGDRLWLRCAARGSPTPRIG-----WTVNDRPVTEGVSEQD-------GGSTLQ 2901
Query: 115 RNAV-QADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTA 173
R AV + D G Y C G QA + V P+ L E G ++ C
Sbjct: 2902 RAAVSREDSGTYVCWAEN-RVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVV 2960
Query: 174 EGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQD 233
G P P + W +K R H R + + + C+ + +
Sbjct: 2961 RGDPVPDIHW---IKDGLPLRG-SHLRHQLQNGSLTIRRTERDDAGRYQCLAEN-----E 3011
Query: 234 QRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGV 293
+ + + L A V +E Q++ + L+C + G+P P+ W + PL +
Sbjct: 3012 MGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASR 3071
Query: 294 RV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVL-DPQEDSGKQVDLVS 347
R+ DG +L + T +G Y C N S ++ + V +PQ G +++
Sbjct: 3072 RLRTLPDG-SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQGSWGSMTGVIN 3129
Score = 44.7 bits (104), Expect = 2e-04
Identities = 63/259 (24%), Positives = 93/259 (35%), Gaps = 34/259 (13%)
Query: 97 RVEQPPPPRNP---LDGSVLLR--NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP-L 150
R E+P P L G +L+ + D G Y C S AG + + VLVPP +
Sbjct: 1106 RGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASN-EAGEARRNFSVEVLVPPSI 1164
Query: 151 PSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHL 210
+ + ++ G T C G P P +TW FK R A H+
Sbjct: 1165 ENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTW------------FKDGRPLARGDAHHI 1212
Query: 211 VPSRSMNGQPLTCVVSHPGLLQ-------DQRITHILHVSFLAEASVRGLE---DQNLWH 260
P + Q L +S G ++ H LA + G E D+ +
Sbjct: 1213 SPDGVLL-QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTV 1271
Query: 261 IGREGAMLKCLSEGQPPPSYNWTRLDGPLPS--GVRVDGDTLGFPPLTT--EHSGIYVCH 316
L C + P P+ W + P + +++ T G L E +G Y C
Sbjct: 1272 TVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCV 1331
Query: 317 VSNEFSSRDSQVTVDVLDP 335
V+NE V+VL P
Sbjct: 1332 VTNELGEAVKNYHVEVLIP 1350
Score = 43.9 bits (102), Expect = 3e-04
Identities = 58/236 (24%), Positives = 90/236 (38%), Gaps = 25/236 (10%)
Query: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP---ALEEGQGLTLAASCTAEGSP 177
DEG Y C + AG + + L+VLVPP ++ PGP A+ E +TL C A G P
Sbjct: 577 DEGIYTCAATNL-AGESKREVALKVLVPP--NIEPGPVNKAVLENASVTL--ECLASGVP 631
Query: 178 APSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRIT 237
P V+W KG S+ + + ++ + CV S+ + R
Sbjct: 632 PPDVSW---FKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYG 688
Query: 238 HILHV--SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPL-PSG-- 292
++V S+ G N L C + G P P+ W + P+ P+G
Sbjct: 689 LRVNVPPRITLPPSLPGPVLVN------TPVRLTCNATGAPSPTLMWLKDGNPVSPAGTP 742
Query: 293 ---VRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDL 345
V G L SG Y C + V + V P G+++++
Sbjct: 743 GLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNV 798
Score = 40.8 bits (94), Expect = 0.003
Identities = 68/303 (22%), Positives = 107/303 (35%), Gaps = 53/303 (17%)
Query: 41 TVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQ 100
TV + L C +G V+W++ A GA+ G VSP+
Sbjct: 2585 TVTMMAPVVLTCH---STGIPAPTVSWSKAGAQLGARGS-------GYRVSPS------- 2627
Query: 101 PPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRV----LVPPLPSLNPG 156
G++ + A+ G Y C AG + L V +V PLPS+
Sbjct: 2628 ---------GALEIGQALPIHAGRYTCSARN-SAGVAHKHVFLTVQASPVVKPLPSVVRA 2677
Query: 157 PALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSM 216
A EE + C A G P P++TW E + S + + H P +
Sbjct: 2678 VAEEE-----VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIA-HASPEDAG 2731
Query: 217 NGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQP 276
N C+ + + ++ V + E + L H A L C + G P
Sbjct: 2732 N---YLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSH-----AFLPCKARGSP 2783
Query: 277 PPSYNWTRLDGPLPSG------VRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTV 330
P+ W + DG SG ++ G+ L L + +G Y C N +V +
Sbjct: 2784 EPNITWDK-DGQPVSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAENAVGRARRRVHL 2841
Query: 331 DVL 333
+L
Sbjct: 2842 TIL 2844
Score = 40.0 bits (92), Expect = 0.005
Identities = 53/237 (22%), Positives = 81/237 (34%), Gaps = 22/237 (9%)
Query: 110 GSVLLRNAVQADE-GEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEE---GQGL 165
G VL V+A+ G Y C+ S G L VL PP+ + +EE
Sbjct: 1521 GRVLQIPLVRAENAGRYSCKASN-EVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 1579
Query: 166 TLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSE---FHLVPSRSMNGQPLT 222
T++ C A G+P P+++W + F S V + + + +
Sbjct: 1580 TVSLQCPALGNPVPTISW------LQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYM 1633
Query: 223 CVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNW 282
CV + ++ T + V + GL+ + + I L C P P W
Sbjct: 1634 CVAENQAGSAEKLFTLRVQV----PPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTW 1689
Query: 283 TRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
+ L G V TL SG+Y C N V + VL P
Sbjct: 1690 YKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP 1746
Score = 34.7 bits (78), Expect = 0.21
Identities = 53/224 (23%), Positives = 87/224 (38%), Gaps = 29/224 (12%)
Query: 111 SVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAAS 170
++LL D ++EC VS G ++ V VPP + + + +
Sbjct: 2538 ALLLTAPGPQDSAQFECVVSN-EVGEAHRLYQVTVHVPPTIA-DDQTDFTVTMMAPVVLT 2595
Query: 171 CTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMN-GQPLTCVVSHPG 229
C + G PAP+V+W S ++ A S + + PS ++ GQ L H G
Sbjct: 2596 CHSTGIPAPTVSW-----------SKAGAQLGARGSGYRVSPSGALEIGQALPI---HAG 2641
Query: 230 LL-----QDQRITHILHVSFLAEAS--VRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNW 282
+ H HV +AS V+ L + + E +L C + G P P+ W
Sbjct: 2642 RYTCSARNSAGVAH-KHVFLTVQASPVVKPLPSV-VRAVAEEEVLLPCEASGIPRPTITW 2699
Query: 283 TRLDGPLPSGVR---VDGDTLGFPPLTTEHSGIYVCHVSNEFSS 323
+ + +GV + G L + E +G Y+C N S
Sbjct: 2700 QKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS 2743
Score = 33.1 bits (74), Expect = 0.62
Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 268 LKCLSEGQPPPSYNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSS 323
L+C + G P P+ +W + P R+ DG L + Y+C N+ S
Sbjct: 1583 LQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGS 1642
Query: 324 RDSQVTVDVLDPQEDSGKQVDLVSA 348
+ T+ V P +G ++ V+A
Sbjct: 1643 AEKLFTLRVQVPPRIAGLDLEQVTA 1667
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 68.9 bits (167), Expect = 1e-11
Identities = 58/222 (26%), Positives = 103/222 (46%), Gaps = 13/222 (5%)
Query: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNP-GPA-LEEGQGLTLAASCTAEGSP 177
++ G Y C V++ G Q+ + L V PP S+ P GP ++ G+ +TL C + G P
Sbjct: 3084 SNHGTYRC-VASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTL--ECVSAGEP 3140
Query: 178 APSVTWDTEVKGTTSS---RSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQ 234
S W T + T + R++ S AV PS + C+ + +
Sbjct: 3141 RSSARW-TRISSTPAKLEQRTYGLMDSHAVLQISSAKPS---DAGTYVCLAQNALGTAQK 3196
Query: 235 RITHILHVSFLAEASVR-GLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGV 293
++ I+ +A + + E+ L A L+C + G P P+ +W++L PLP
Sbjct: 3197 QVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQH 3256
Query: 294 RVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
R++GDTL P + + SG Y+C+ ++ ++ + + V P
Sbjct: 3257 RLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESP 3298
Score = 68.9 bits (167), Expect = 1e-11
Identities = 59/221 (26%), Positives = 96/221 (43%), Gaps = 15/221 (6%)
Query: 100 QPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPAL 159
Q PP + DG + ++N Q+ +G Y C+ P G QA +L + P +N ++
Sbjct: 3439 QLPPGHSVQDGVLRIQNLDQSCQGTYICQAHG-PWGKAQASAQLVIQALPSVLINIRTSV 3497
Query: 160 EEGQ-GLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNG 218
+ G + C A G P P VTW ++V G + S V H+ + + G
Sbjct: 3498 QTVVVGHAVEFECLALGDPKPQVTW-SKVGGHLRPGIVQ---SGGVVRIAHVELADA--G 3551
Query: 219 QPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPP 278
Q + G Q HV L +A + Q + A+ C++ G P P
Sbjct: 3552 QYRCTATNAAGTTQS-------HVLLLVQALPQISMPQEVRVPAGSAAVFPCIASGYPTP 3604
Query: 279 SYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSN 319
+W++LDG LP R++ + L P + + +G YVC +N
Sbjct: 3605 DISWSKLDGSLPPDSRLENNMLMLPSVRPQDAGTYVCTATN 3645
Score = 66.6 bits (161), Expect = 5e-11
Identities = 69/250 (27%), Positives = 102/250 (40%), Gaps = 34/250 (13%)
Query: 103 PPRNPLDGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP---LPSLNPGPA 158
P R+ GS+L L A AD GEY CRV S + V + P +P+L P
Sbjct: 2382 PVRHQTHGSLLRLYQASPADSGEYVCRVL---GSSVPLEASVLVTIEPAGSVPALGVTPT 2438
Query: 159 L-------EEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLV 211
+ + +G TL +C G VTW G+ +R H + +
Sbjct: 2439 VRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKR-GGSLPARHQVHGSRLRL---LQVT 2494
Query: 212 PSRSMNGQPLTCVVSHPGLLQ-------DQRIT--HILHVSFLAEASVRGLEDQNLWHIG 262
P+ S G+ + VV G + QR++ H V++ +E +
Sbjct: 2495 PADS--GEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVR-----IESSSASLAN 2547
Query: 263 REGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFS 322
L CL Q P + W + G LPS ++ G L P +T SG YVCHVSN
Sbjct: 2548 GHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAG 2607
Query: 323 SRDSQVTVDV 332
SR++ + V +
Sbjct: 2608 SRETSLIVTI 2617
Score = 65.1 bits (157), Expect = 1e-10
Identities = 76/299 (25%), Positives = 118/299 (39%), Gaps = 22/299 (7%)
Query: 91 SPAYE---GRVEQPPPPRNPLD--GSVLLRNAVQADEGEYECRVST-FPAGSFQARLRLR 144
SPAY R+ P +D G + +RN +D G Y C S F A L ++
Sbjct: 1799 SPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQ 1858
Query: 145 V---LVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRS 201
L P+ S++P P L G C+A GSP P++ W G +++ H
Sbjct: 1859 ASGTLSAPVVSIHP-PQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQIHGGI 1917
Query: 202 AAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHI 261
+ P+ Q +H Q Q +LHV V+ ++ H
Sbjct: 1918 LRL-------PAVEPTDQAQYLCRAHSSAGQ-QVARAVLHVHGGGGPRVQVSPERTQVHA 1969
Query: 262 GREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVR---VDGDTLGFPPLTTEHSGIYVCHVS 318
GR L C + G P + W + G LP R D TL P +TT +G Y+C +
Sbjct: 1970 GRT-VRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVAT 2028
Query: 319 NEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRR 377
+ + +++ V VL + S V + S+S V L C++ ++RR
Sbjct: 2029 SPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRR 2087
Score = 63.9 bits (154), Expect = 3e-10
Identities = 61/234 (26%), Positives = 96/234 (41%), Gaps = 9/234 (3%)
Query: 103 PPRNPLDGSVLLRNAVQ-ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEE 161
P + + G +L AV+ D+ +Y CR + AG AR L V P + P +
Sbjct: 1908 PAKAQIHGGILRLPAVEPTDQAQYLCRAHS-SAGQQVARAVLHVHGGGGPRVQVSPERTQ 1966
Query: 162 GQ-GLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPS-RSMNGQ 219
G T+ C A G P+ ++TW E G + + R+ T L+P+ + +
Sbjct: 1967 VHAGRTVRLYCRAAGVPSATITWRKE--GGSLPPQARSERTDIATL---LIPAITTADAG 2021
Query: 220 PLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS 279
CV + P RI ++ + A +E + + L C+ G
Sbjct: 2022 FYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQ 2081
Query: 280 YNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVL 333
W R G LP +V G L P ++ SG YVC V N +++ +TV VL
Sbjct: 2082 VTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVL 2135
Score = 60.1 bits (144), Expect = 5e-09
Identities = 74/303 (24%), Positives = 118/303 (38%), Gaps = 46/303 (15%)
Query: 40 VTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVE 99
V V +G+ L C +GE W R+ + E YGL S A
Sbjct: 3122 VWVKVGKAVTLECV---SAGEPRSSARWTRISSTPAKLE----QRTYGLMDSHAV----- 3169
Query: 100 QPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRV----LVPPLPSLNP 155
+ + +A +D G Y C G+ Q ++ + V + P P +
Sbjct: 3170 ------------LQISSAKPSDAGTYVCLAQN-ALGTAQKQVEVIVDTGAMAPGAPQVQA 3216
Query: 156 GPA-LEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVP-- 212
A L G T C+A GSPAP++ W S ++H + + ++P
Sbjct: 3217 EEAELTVEAGHTATLRCSATGSPAPTIHWSK----LRSPLPWQHR----LEGDTLIIPRV 3268
Query: 213 SRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLS 272
++ +GQ + S G + T ILHV A+ + + G E L+CL+
Sbjct: 3269 AQQDSGQYICNATSPAGHAE---ATIILHVESPPYATT--VPEHASVQAG-ETVQLQCLA 3322
Query: 273 EGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332
G PP ++ W+R+ LP + L F E SG Y C V+N+ S ++ + V
Sbjct: 3323 HGTPPLTFQWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLV 3382
Query: 333 LDP 335
P
Sbjct: 3383 QGP 3385
Score = 56.2 bits (134), Expect = 7e-08
Identities = 69/279 (24%), Positives = 104/279 (37%), Gaps = 30/279 (10%)
Query: 103 PPRNPLDGSVLLRNAVQ-ADEGEYECRVSTFPAGSFQARLRLRV---------LVPPLPS 152
P R+ GS L + V AD GEY CR ++ P +A + V L P+ S
Sbjct: 2966 PARHQTHGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVIS 3025
Query: 153 LNPGPALEEGQGLTLAASCTAEGSPAP-SVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLV 211
++P P+ QG + C AP S+ W T + + + S +V
Sbjct: 3026 IDP-PSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIIT-----IV 3079
Query: 212 PSRSMNGQPLTCVVSHP-GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKC 270
+R N CV S+ G+ Q ++++S +V L + +W + L+C
Sbjct: 3080 GTRPSNHGTYRCVASNAYGVAQS-----VVNLSVHGPPTVSVLPEGPVWVKVGKAVTLEC 3134
Query: 271 LSEGQPPPSYNWTRLDGPLPS------GVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSR 324
+S G+P S WTR+ G+ L +G YVC N +
Sbjct: 3135 VSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTA 3194
Query: 325 DSQVTVDV-LDPQEDSGKQVDLVSASVVVVGVIAALLFC 362
QV V V QV A + V A L C
Sbjct: 3195 QKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRC 3233
Score = 51.2 bits (121), Expect = 2e-06
Identities = 62/248 (25%), Positives = 91/248 (36%), Gaps = 24/248 (9%)
Query: 103 PPRNPLDGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVL--VPPLPSLNPGP-- 157
PP + GS L L AD GEY CRV +G +A + + VL PS P P
Sbjct: 2092 PPHTQVHGSRLRLPQVSPADSGEYVCRVEN-GSGPKEASITVSVLHGTHSGPSYTPVPGS 2150
Query: 158 ---------ALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEF 208
+ +G TL +C G VTW S +H ++
Sbjct: 2151 TRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKR----GGSLPARHQTHGSLLRLH 2206
Query: 209 HLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAML 268
+ P+ S G+ + VV G L+ + I +E + + L
Sbjct: 2207 QVTPADS--GEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDL 2264
Query: 269 KCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQV 328
C+ GQ W + G LP+ +V G L + +G YVC SN ++ +
Sbjct: 2265 SCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASN---GMEASI 2321
Query: 329 TVDVLDPQ 336
TV V Q
Sbjct: 2322 TVTVTGTQ 2329
Score = 51.2 bits (121), Expect = 2e-06
Identities = 79/344 (22%), Positives = 121/344 (35%), Gaps = 66/344 (19%)
Query: 41 TVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSK-YGLHVSPAYEG--- 96
T V G +LP DSGE V RV+ G G +E ++ S +G H P+Y
Sbjct: 2095 TQVHGSRLRLPQVSPADSGEYV-----CRVENGSGPKEASITVSVLHGTHSGPSYTPVPG 2149
Query: 97 -----RVEQPP--------------------------------PPRNPLDGSVL-LRNAV 118
R+E P R+ GS+L L
Sbjct: 2150 STRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLLRLHQVT 2209
Query: 119 QADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEG-----QGLTLAASCTA 173
AD GEY C V +G +A + + + +P P +E +G TL SC
Sbjct: 2210 PADSGEYVCHV-VGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVV 2268
Query: 174 EGSPAPSVTWDTEVKGTTSSRSFKHSRS---AAVTSEFHLVPSRSMNGQPLTCVVSHPGL 230
G VTW + + SR A ++ R+ NG + V+ G
Sbjct: 2269 AGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASNGMEASITVTVTG- 2327
Query: 231 LQDQRITHILHVSFLAEAS--VRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGP 288
T ++++ A ++ +R +E + + L C+ GQ W + G
Sbjct: 2328 ------TQGANLAYPAGSTQPIR-IEPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGS 2380
Query: 289 LPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDV 332
LP + G L + SG YVC V ++ V V +
Sbjct: 2381 LPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTI 2424
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/249 (23%), Positives = 94/249 (37%), Gaps = 32/249 (12%)
Query: 103 PPRNPLDGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEE 161
P R+ + GS L L AD GEY CRV +G+ +A + + + S + G A
Sbjct: 2478 PARHQVHGSRLRLLQVTPADSGEYVCRV-VGSSGTQEASVLVTIQQRLSGSHSQGVAYPV 2536
Query: 162 ---------GQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSR------SAAVTS 206
G TL +C ++TW S SR + A +
Sbjct: 2537 RIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRIPQVTPADSG 2596
Query: 207 EFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVS---FLAEASVRGLEDQNLWHIGR 263
E+ S + + +V+ +Q +H+ VS + +S +E Q L
Sbjct: 2597 EYVCHVSNGAGSRETSLIVT----IQGSGSSHVPSVSPPIRIESSSPTVVEGQTL----- 2647
Query: 264 EGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSS 323
L C+ QP W + G LPS + G L ++ SG YVC +N +
Sbjct: 2648 ---DLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDA 2704
Query: 324 RDSQVTVDV 332
++ + + V
Sbjct: 2705 LEASIVISV 2713
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/247 (23%), Positives = 92/247 (37%), Gaps = 24/247 (9%)
Query: 103 PPRNPLDGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPAL-- 159
P R+ GS L L AD GEY CR + + +A + + V PG ++
Sbjct: 2671 PSRHQTHGSHLRLHQMSVADSGEYVCRANN-NIDALEASIVISVSPSAGSPSAPGSSMPI 2729
Query: 160 -------EEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVP 212
+G TL +C G VTW S + SR H+ P
Sbjct: 2730 RIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRGSRLRL----HHVSP 2785
Query: 213 SRSMNGQPLTCVVSHPGLLQDQRITHI-------LHVSFLAEASVRGLEDQNLWHIGREG 265
+ S G+ + V+ G L+ + I +HV A +E + +
Sbjct: 2786 ADS--GEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQT 2843
Query: 266 AMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRD 325
LKC+ GQ W + G LP+ +V G L ++ SG Y C V+ + +
Sbjct: 2844 LDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLE 2903
Query: 326 SQVTVDV 332
+ V V +
Sbjct: 2904 ASVLVTI 2910
Score = 46.6 bits (109), Expect = 5e-05
Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 268 LKCLSEGQPPPSYNWTRLDG-PLPSGV--RVDGDTLGFPPLTTEHSGIYVCHVSNEFSSR 324
L+C G PP + W+R DG P+PSG R G L FP + +G+Y+C N S
Sbjct: 1696 LRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPSVQPSDAGVYICTCRNLHQSN 1755
Query: 325 DSQVTVDVLD 334
S+ + V +
Sbjct: 1756 TSRAELLVTE 1765
Score = 43.1 bits (100), Expect = 6e-04
Identities = 77/321 (23%), Positives = 109/321 (33%), Gaps = 59/321 (18%)
Query: 68 ARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVL-LRNAVQADEGEYE 126
A V AGE Q L H L + RV P R +L A D G Y
Sbjct: 3308 ASVQAGETVQLQCLAHGTPPLTFQWS---RVGSSLPGRATARNELLHFERAAPEDSGRYR 3364
Query: 127 CRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTE 186
CRV T GS +A +L V PP G A S A +P VT E
Sbjct: 3365 CRV-TNKVGSAEAFAQLLVQGPP--------------GSLPATSIPAGSTPTVQVTPQLE 3409
Query: 187 VKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVS-HPGLLQDQRITHILHVSFL 245
K +S F AV S+ G L S G+L+ Q + +++
Sbjct: 3410 TKSIGASVEFH----CAVPSDRGTQLRWFKEGGQLPPGHSVQDGVLRIQNLDQSCQGTYI 3465
Query: 246 AEASVRGLEDQNLWHIGREGAML---------------------------KCLSEGQPPP 278
+A W + A L +CL+ G P P
Sbjct: 3466 CQA-------HGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKP 3518
Query: 279 SYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD-PQE 337
W+++ G L G+ G + + +G Y C +N + S V + V PQ
Sbjct: 3519 QVTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQI 3578
Query: 338 DSGKQVDLVSASVVVVGVIAA 358
++V + + S V IA+
Sbjct: 3579 SMPQEVRVPAGSAAVFPCIAS 3599
Score = 43.1 bits (100), Expect = 6e-04
Identities = 41/147 (27%), Positives = 58/147 (39%), Gaps = 33/147 (22%)
Query: 37 SDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEG 96
+ V TVV+G + C GD QV W SK G H+ P G
Sbjct: 3495 TSVQTVVVGHAVEFECLALGDPKP---QVTW----------------SKVGGHLRP---G 3532
Query: 97 RVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPG 156
V+ G V + + AD G+Y C +T AG+ Q+ + L LV LP ++
Sbjct: 3533 IVQS--------GGVVRIAHVELADAGQYRC-TATNAAGTTQSHVLL--LVQALPQISMP 3581
Query: 157 PALEEGQGLTLAASCTAEGSPAPSVTW 183
+ G C A G P P ++W
Sbjct: 3582 QEVRVPAGSAAVFPCIASGYPTPDISW 3608
Score = 39.7 bits (91), Expect = 0.007
Identities = 64/262 (24%), Positives = 94/262 (35%), Gaps = 39/262 (14%)
Query: 103 PPRNPLDGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVP-------PLPSLN 154
P + GS L L + AD GEY CRV +G +A + + + P P
Sbjct: 2768 PSHHQTRGSRLRLHHVSPADSGEYVCRVMG-SSGPLEASVLVTIEASGSSAVHVPAPGGA 2826
Query: 155 PGPALEEG-----QGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSR-------SA 202
P +E +G TL C G VTW G +R H S
Sbjct: 2827 PPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKR-GGNLPARHQVHGPLLRLNQVSP 2885
Query: 203 AVTSEFHLVPSRSMNGQPLTCVV----SHPGLLQDQRITHILHVSFLAEASVRGLEDQNL 258
A + E+ + S + +V S PG + + +++ +S E Q L
Sbjct: 2886 ADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIE---ASSSHVTEGQTL 2942
Query: 259 WHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCH-V 317
L C+ GQ W + G LP+ + G L ++ SG YVC
Sbjct: 2943 --------DLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPADSGEYVCRAA 2994
Query: 318 SNEFSSRDSQVTVDVLDPQEDS 339
S +++ TV V P E S
Sbjct: 2995 SGPGPEQEASFTVTV-PPSEGS 3015
Score = 29.3 bits (64), Expect = 8.9
Identities = 11/37 (29%), Positives = 19/37 (51%)
Query: 147 VPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTW 183
+PP P +++ +G T+ +C A G P P + W
Sbjct: 404 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINW 440
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 66.6 bits (161), Expect = 5e-11
Identities = 80/319 (25%), Positives = 122/319 (38%), Gaps = 49/319 (15%)
Query: 26 TGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSK 85
TG P ++ V V+ GQ LPC +G + + W +
Sbjct: 763 TGHAPPQIASSAPTVRVLEGQPVSLPCIVL--AGRPLPERHWLK---------------- 804
Query: 86 YGLHVSPAYEGRVEQPPPPRNPL--DGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRL 143
+GR PP R+ + DGS+ L A+Q G Y C V+T AGS + L
Sbjct: 805 ---------DGR-PLPPGSRHSIRADGSLHLDRALQEHAGRYSC-VATNTAGSQHRDVEL 853
Query: 144 RVLVPPLPSLNPGPALE-EGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSA 202
V VPP ++P +G+ + C A G PAP++TW E TS R ++ S
Sbjct: 854 VVQVPP--RIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTS-RGPHYNVSK 910
Query: 203 AVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNL---- 258
T + + + C ++ Q + L V+ + G + N+
Sbjct: 911 EGT--LLIAQPSAQDAGAYVCTATNTVGFSSQEMR--LSVNTKPRIHMNGSRNANVPLQV 966
Query: 259 WHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPS-----GVRVDGDTLGFPPLTTEHSGIY 313
E L C ++G PPP WT+ P+P G+ G +L + SG Y
Sbjct: 967 TAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSG-SLRLAQVQVGDSGHY 1025
Query: 314 VCHVSNEFSSRDSQVTVDV 332
C SN S + + V
Sbjct: 1026 ECTASNPAGSASHRYVLGV 1044
Score = 61.2 bits (147), Expect = 2e-09
Identities = 64/250 (25%), Positives = 105/250 (42%), Gaps = 20/250 (8%)
Query: 117 AVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGS 176
A +A+EG YEC + AG+ +A+ ++ V PP P L P P + G T SC G
Sbjct: 369 ASKAEEGTYEC-TAVSRAGTGRAKAQIVVTDPP-PQLVPAPNVTVSPGETAVLSCRVLGE 426
Query: 177 PAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFH-LVPSRSMNGQPLTCVVSHPGLLQDQR 235
++TW + + +S + ++ A ++ E ++P+ +G CV S+
Sbjct: 427 APYNLTWVRDWRVLPASTG-RVAQLADLSLEISGIIPT---DGGRYQCVASNA-----NG 477
Query: 236 ITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRV 295
+T + EA + + + C + G P P +W+R L R+
Sbjct: 478 VTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRI 537
Query: 296 DGD---TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVV 352
D TL + E +G Y C +NE + VT+ DP V V+A V+V
Sbjct: 538 HVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDP-----PSVSAVNAVVLV 592
Query: 353 VGVIAALLFC 362
A+L C
Sbjct: 593 AVGEEAVLVC 602
Score = 57.0 bits (136), Expect = 4e-08
Identities = 73/306 (23%), Positives = 118/306 (38%), Gaps = 42/306 (13%)
Query: 30 PAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLH 89
P +L + VTV G+ A L C G++ + W R
Sbjct: 399 PPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNL---TWVR-----------------DWR 438
Query: 90 VSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP 149
V PA GRV Q D S+ + + D G Y+C V++ G +A + L V P
Sbjct: 439 VLPASTGRVAQLA------DLSLEISGIIPTDGGRYQC-VASNANGVTRASVWLLVREAP 491
Query: 150 LPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFH 209
S++ + QG+ + SC+A G P P ++W E + S H +
Sbjct: 492 QVSIHTS-SQHFSQGVEVKVSCSASGYPTPHISWSRESQALQED-SRIHVDAQGTLIIQG 549
Query: 210 LVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLK 269
+ P + N +C ++ + +T + + SV + L +G E A+L
Sbjct: 550 VAPEDAGN---YSCQATNEVGTDQETVT----LYYTDPPSVSAVNAVVLVAVGEE-AVLV 601
Query: 270 CLSEGQPPPSYNWTRLDGPLPSGVRVDGDTLG---FPPLTTEHSGIYVCHVSNEFSSRDS 326
C + G PPP W R G L + +G + G P +G Y C NE +
Sbjct: 602 CEASGVPPPRVIWYR--GGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASA 659
Query: 327 QVTVDV 332
++ + V
Sbjct: 660 EIQLAV 665
Score = 54.7 bits (130), Expect = 2e-07
Identities = 75/256 (29%), Positives = 103/256 (40%), Gaps = 30/256 (11%)
Query: 94 YEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRV-LVPPLPS 152
Y G +E P G + + A + D G Y CR G A ++L V P L
Sbjct: 615 YRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVN-ELGDASAEIQLAVGHAPQLTE 673
Query: 153 LNPGPALEEGQGLTLAASCTAEGSPAPSVTW---DTEVKGTTSSRSFKHSRSAAVTSEFH 209
L +E G+ LA C A G P P+VTW D + G + SRS S
Sbjct: 674 LPRDVTVELGRSALLA--CRATGRPPPTVTWRRGDGQPLGLRLGAG-RGSRSRQPDSGVL 730
Query: 210 LVPSRSMNGQ-PLTCVVSHP-GLLQ-DQRITHILHVSFLAEAS---VRGLEDQNLWHIGR 263
S + Q P C + G +Q + R+ H +S VR LE Q +
Sbjct: 731 FFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPV----- 785
Query: 264 EGAMLKCL-SEGQPPPSYNWTRLDGPLPSG----VRVDGDTLGFPPLTTEHSGIYVCHVS 318
L C+ G+P P +W + PLP G +R DG +L EH+G Y C +
Sbjct: 786 ---SLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADG-SLHLDRALQEHAGRYSCVAT 841
Query: 319 NEFSS--RDSQVTVDV 332
N S RD ++ V V
Sbjct: 842 NTAGSQHRDVELVVQV 857
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 65.5 bits (158), Expect = 1e-10
Identities = 79/331 (23%), Positives = 134/331 (40%), Gaps = 30/331 (9%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAA-SCT 172
LR EG Y+C ++ ++ + RL V V LPS P + T+A C
Sbjct: 564 LRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNV--LPSFTKTPHDITIRTTTMARLECA 621
Query: 173 AEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSE--FHLVPSRSMNGQPLTCVVSHP-G 229
A G P P + W + G T + + R + + F + + + +C + G
Sbjct: 622 ATGHPNPQIAWQKD--GGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQNSAG 679
Query: 230 LLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPL 289
+ +L L V LED+ + +G E L+C + G PPP W + D PL
Sbjct: 680 SISANATLTVLETPSL----VVPLEDRVV-SVG-ETVALQCKATGNPPPRITWFKGDRPL 733
Query: 290 PSGVR----VDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDL 345
R D L + E +G Y C +SN + + + VL +G + D
Sbjct: 734 SLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLPA---AGCRKDG 790
Query: 346 VSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHH 405
+ + + V+++++ LV V ++ Y RK + + T+ + L S
Sbjct: 791 TTVGIFTIAVVSSIVLTSLVWVCII---YQTRKKSEEYSVTNTDETVVPPDVPSYLSSQG 847
Query: 406 TDPRSQPEESVGLRAEGHPDS---LKDNSSC 433
T S +E+V +R EG P + ++ N C
Sbjct: 848 T--LSDRQETV-VRTEGGPQANGHIESNGVC 875
Score = 41.2 bits (95), Expect = 0.002
Identities = 51/201 (25%), Positives = 73/201 (36%), Gaps = 47/201 (23%)
Query: 17 LLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGA 76
L + +L SFT +T +T+ A+L C +G Q+AW + +G
Sbjct: 593 LTVNVLPSFT--------KTPHDITIRTTTMARLEC---AATGHPNPQIAWQK----DGG 637
Query: 77 QELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADE-GEYECRVSTFPAG 135
+ + +HV P D V V+ D+ G Y C AG
Sbjct: 638 TDFPAARERR-MHVMP----------------DDDVFFITDVKIDDAGVYSCTAQN-SAG 679
Query: 136 SFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRS 195
S A L VL P + P G T+A C A G+P P +TW
Sbjct: 680 SISANATLTVLETP-SLVVPLEDRVVSVGETVALQCKATGNPPPRITW------------ 726
Query: 196 FKHSRSAAVTSEFHLVPSRSM 216
FK R ++T HL P +
Sbjct: 727 FKGDRPLSLTERHHLTPDNQL 747
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 63.5 bits (153), Expect = 4e-10
Identities = 62/241 (25%), Positives = 93/241 (38%), Gaps = 14/241 (5%)
Query: 109 DGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPA--LEEGQGL 165
+GS L + A+ +D G+Y C V+T PAG L V V P N A L
Sbjct: 3300 NGSTLNIYGALTSDTGKYTC-VATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358
Query: 166 TLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVV 225
++ C A G+P P + W +K H R A +V ++ + TCV
Sbjct: 3359 SINIECRATGTPPPQINW---LKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVA 3415
Query: 226 SHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRL 285
S+ + ++ H F + + + + + C+++G P PS W R
Sbjct: 3416 SNRAGVDNK---HYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD 3472
Query: 286 DGPLPSG----VRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGK 341
PL V G L TE SG Y C SNE + VL+P +G
Sbjct: 3473 GQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGS 3532
Query: 342 Q 342
+
Sbjct: 3533 E 3533
Score = 61.2 bits (147), Expect = 2e-09
Identities = 69/269 (25%), Positives = 105/269 (39%), Gaps = 29/269 (10%)
Query: 116 NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNP--GPALEEGQ-----GLTLA 168
NA + + G Y C V+T AG ++V +PP+ + GP L + TL
Sbjct: 2635 NAQEDNAGRYSC-VATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLT 2693
Query: 169 ASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228
C A P+ S++W K +S H AA + ++ + TCV S+
Sbjct: 2694 LECEAYAIPSASLSW---YKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASN- 2749
Query: 229 GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAM----------LKCLSEGQPPP 278
+ + + +++ + + + E N+ GR G L C + PPP
Sbjct: 2750 -IAGEDELDFDVNIQ-VPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPP 2807
Query: 279 SYNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD 334
+ W + PL S +V G L P E +G Y C NE Q V VL
Sbjct: 2808 TLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLV 2867
Query: 335 PQEDSGKQVDLVSASVVVVGVIAALLFCL 363
P G DL V+V +AL+ CL
Sbjct: 2868 PPIIKGANSDLPEEVTVLVNK-SALIECL 2895
Score = 57.4 bits (137), Expect = 3e-08
Identities = 53/223 (23%), Positives = 91/223 (40%), Gaps = 13/223 (5%)
Query: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPA-LEEGQGLTLAASCTAEGSPA 178
+D G Y C S G Q L + VPP + P+ + G + C A G P
Sbjct: 3217 SDSGNYTCIASNME-GKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT 3275
Query: 179 PSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITH 238
P + W + K S + + R +A S ++ + + + TCV ++P +D+
Sbjct: 3276 PLIQWLKDGKPIASGET-ERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDR---- 3330
Query: 239 ILHVSFLAEASVRGLEDQ--NLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLP--SGVR 294
I +++ ++RG +D+ L + ++C + G PPP NW + PLP S +R
Sbjct: 3331 IFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIR 3390
Query: 295 V--DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
+ G + +Y C SN + + V P
Sbjct: 3391 LLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAP 3433
Score = 57.0 bits (136), Expect = 4e-08
Identities = 57/243 (23%), Positives = 99/243 (40%), Gaps = 15/243 (6%)
Query: 97 RVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPG 156
R+ +P R + S+ L++ D GEY C VS+ GS A + L V PP ++ P
Sbjct: 561 RLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSS-EGGSSAASVFLTVQEPPKVTVMPK 619
Query: 157 PALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSM 216
G G ++ C+A G P P + W S ++ + + + +
Sbjct: 620 NQSFTG-GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGI 678
Query: 217 NGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQP 276
G C+ S+ Q T + ++ + ++ + L +G + +++C + G P
Sbjct: 679 YG----CLASNSAGTDKQNST----LRYIEAPKLMVVQSELLVALG-DITVMECKTSGIP 729
Query: 277 PPSYNWTRLDGPL-PSGVRVDGDTLGFPPLTTEH---SGIYVCHVSNEFSSRDSQVTVDV 332
PP W + D L PS + LG + +G Y C NE ++T+DV
Sbjct: 730 PPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDV 789
Query: 333 LDP 335
P
Sbjct: 790 GSP 792
Score = 56.6 bits (135), Expect = 5e-08
Identities = 60/234 (25%), Positives = 98/234 (41%), Gaps = 25/234 (10%)
Query: 110 GSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEE---GQGLT 166
G + + AV+ D G Y C V+ PAG+ +++L V VPP+ S P L+E
Sbjct: 4041 GGLQISRAVREDAGTYMC-VAQNPAGTALGKIKLNVQVPPVIS----PHLKEYVIAVDKP 4095
Query: 167 LAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVS 226
+ SC A+G P P +TW + + S + S ++ F + + TC+ +
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAF----VQPGDAGHYTCMAA 4151
Query: 227 HPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTR-- 284
+ +HV +R E + + A+L C+++G P P+ NW +
Sbjct: 4152 NVAGSSSTSTKLTVHV----PPRIRSTEGHYTVNENSQ-AILPCVADGIPTPAINWKKDN 4206
Query: 285 --LDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDS---QVTVDVL 333
L L L + E SG Y C V+N + D+ +TV VL
Sbjct: 4207 VLLANLLGKYTAEPYGELILENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVL 4259
Score = 56.2 bits (134), Expect = 7e-08
Identities = 57/235 (24%), Positives = 93/235 (39%), Gaps = 14/235 (5%)
Query: 109 DGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPA-LEEGQGLTL 167
DGS+ + D GEY C S + + V+V LP++ G L +G+ +
Sbjct: 942 DGSLHIERVQLQDGGEYTCVASNVAGTNNKTT---SVVVHVLPTIQHGQQILSTIEGIPV 998
Query: 168 AASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSH 227
C A G+P PSV W KG S S + A S + + P +G+ C ++
Sbjct: 999 TLPCKASGNPKPSVIWSK--KGELISTSSAKFSAGADGSLYVVSPGGEESGE-YVCTATN 1055
Query: 228 PGLLQDQRITHILHVSFLAEASVRGLEDQ---NLWHIGREGAMLKCLSEGQPPPSYNW-- 282
+++ ++V RGL + + E L C + PPP W
Sbjct: 1056 TAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAK 1115
Query: 283 -TRLDGPL-PSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
T+L P P + ++ T SG+Y+C +N + V ++V P
Sbjct: 1116 ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVP 1170
Score = 52.4 bits (124), Expect = 1e-06
Identities = 58/258 (22%), Positives = 103/258 (39%), Gaps = 18/258 (6%)
Query: 110 GSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLT-- 166
G VL L+NA + D+G Y+C VS AG ++L + +PP S+ G + L
Sbjct: 1507 GQVLHLKNARRNDKGRYQCTVSN-AAGKQAKDIKLTIYIPP--SIKGGNVTTDISVLINS 1563
Query: 167 -LAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVV 225
+ C G P P++TW + + SS + H+ ++ + TC V
Sbjct: 1564 LIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKG---QYLHIPRAQVSDSATYTCHV 1620
Query: 226 SHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRL 285
++ ++ ++V + E ++ N + L+C + G P P W +
Sbjct: 1621 ANVAGTAEKSFHVDVYVPPMIEGNL--ATPLNKQVVIAHSLTLECKAAGNPSPILTWLKD 1678
Query: 286 DGPLPSG----VRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGK 341
P+ + + G L G Y+C ++ ++ + VDVL P G
Sbjct: 1679 GVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGG 1738
Query: 342 QVDLVSASVVVVGVIAAL 359
D S +V+V + L
Sbjct: 1739 --DETSYFIVMVNNLLEL 1754
Score = 51.6 bits (122), Expect = 2e-06
Identities = 64/260 (24%), Positives = 95/260 (36%), Gaps = 32/260 (12%)
Query: 109 DGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLA 168
DG++ ++NA D G Y C S AG+ + LR + P + L +T+
Sbjct: 663 DGTLFIKNAAPKDAGIYGCLASN-SAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVM 721
Query: 169 ASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228
C G P P V W KG R + + ++ ++ TCV +
Sbjct: 722 -ECKTSGIPPPQVKW---FKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINE 777
Query: 229 GLLQDQRITHILHVS----FLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTR 284
+IT L V F+ E + +E IG L C +G P P+ W R
Sbjct: 778 AGRATGKIT--LDVGSPPVFIQEPADVSME------IG-SNVTLPCYVQGYPEPTIKWRR 828
Query: 285 LDG--------PLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQ 336
LD + S ++ L L G Y+C N+F S+ TV V
Sbjct: 829 LDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV---- 884
Query: 337 EDSGKQVDLVSASVVVVGVI 356
+G L+ S V VI
Sbjct: 885 --TGLVAPLIGISPSVANVI 902
Score = 49.7 bits (117), Expect = 6e-06
Identities = 51/231 (22%), Positives = 100/231 (43%), Gaps = 19/231 (8%)
Query: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGL--TLAASCTAEGSP 177
+D Y C V+ AG+ + + V VPP+ N L + + +L C A G+P
Sbjct: 1611 SDSATYTCHVANV-AGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNP 1669
Query: 178 APSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRIT 237
+P +TW +K ++ + R A + ++ ++ ++ CV + + ++ I
Sbjct: 1670 SPILTW---LKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT--SVAGEKEIK 1724
Query: 238 HILHVSFLAEASVRGLEDQNLWHIGREGAM-LKCLSEGQPPPSYNWTRLDGPLPS----- 291
+ V L ++ G ++ + + + + L C G PPP+ W + DG L
Sbjct: 1725 Y--EVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLK-DGQLIDERDGF 1781
Query: 292 GVRVDGDTLGFPPLTTEHSGIYVCHVSNEFS--SRDSQVTVDVLDPQEDSG 340
+ ++G L ++G+Y C +N ++ +VTV V + SG
Sbjct: 1782 KILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSG 1832
Score = 49.7 bits (117), Expect = 6e-06
Identities = 67/321 (20%), Positives = 120/321 (37%), Gaps = 47/321 (14%)
Query: 40 VTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVE 99
VTV++ + A + C SG + +W + +G L H K+ GR+
Sbjct: 2882 VTVLVNKSALIECL---SSGSPAPRNSWQK----DGQPLLEDDHHKF------LSNGRIL 2928
Query: 100 QPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPAL 159
Q + N D G Y C V+ AGS + L V VPP L
Sbjct: 2929 Q-------------ILNTQITDIGRYVC-VAENTAGSAKKYFNLNVHVPPSVIGPKSENL 2974
Query: 160 EEGQGLTLAASCTAEGSPAPSVTW---DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSM 216
++ +C G P P ++W + +K T++ R+ ++ ++
Sbjct: 2975 TVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT------LQIIRAKVS 3028
Query: 217 NGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIG-REGAM--LKCLSE 273
+G TC+ + ++ + ++V S++ + ++L + REG L+C S
Sbjct: 3029 DGGEYTCIAINQAGESKKKFSLTVYVP----PSIKDHDSESLSVVNVREGTSVSLECESN 3084
Query: 274 GQPPPSYNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVT 329
PPP W + + V DG L +G YVC N D
Sbjct: 3085 AVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFH 3144
Query: 330 VDVLDPQEDSGKQVDLVSASV 350
++V P G + +++ ++
Sbjct: 3145 LNVYVPPSIEGPEREVIVETI 3165
Score = 49.3 bits (116), Expect = 8e-06
Identities = 56/244 (22%), Positives = 102/244 (41%), Gaps = 32/244 (13%)
Query: 109 DGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLP-----SLNPGPALE--- 160
DGS+ + + + GEY C +T AG + +++L V V P L+ +E
Sbjct: 1033 DGSLYVVSPGGEESGEYVC-TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISV 1091
Query: 161 -EGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQ 219
G+ +TL C + P P +TW K T F + + + +R+ +
Sbjct: 1092 LAGEEVTLP--CEVKSLPPPIITW---AKETQLISPFSPRHTFLPSGSMKITETRTSDSG 1146
Query: 220 PLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS 279
CV ++ Q + +HV + + L+ Q +G+ + C ++G P P
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQ----VGQR-VDIPCNAQGTPLPV 1201
Query: 280 YNWTRLDGPLPSGVRVDGD--------TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVD 331
W++ S + VDG+ TL T +GIY C +N + ++++T+
Sbjct: 1202 ITWSKGG----STMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 332 VLDP 335
V +P
Sbjct: 1258 VQEP 1261
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/253 (23%), Positives = 104/253 (41%), Gaps = 19/253 (7%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP-LPSLNPGPALEEGQGLTLAASCT 172
+ +A +D G Y+C V+ AG+ + L+V V P + N A+ + L C
Sbjct: 1978 IESAQISDAGIYKC-VAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRL--ECE 2034
Query: 173 AEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQP-LTCVVSHPGLL 231
A G PAPS+TW +K + SF + + S ++ TCV +
Sbjct: 2035 ARGIPAPSLTW---LKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 2091
Query: 232 QDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPS 291
+ + I ++V ++ G E+QN+ + + L C S+ PPP+ W + PL
Sbjct: 2092 KQRDIDLRVYVP----PNIMG-EEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLK 2146
Query: 292 ----GVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVS 347
+ + L + +G Y C +N + V++ P G D ++
Sbjct: 2147 KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGS--DELT 2204
Query: 348 ASVVVVGVIAALL 360
V+ G + +LL
Sbjct: 2205 QLTVIEGNLISLL 2217
Score = 49.3 bits (116), Expect = 8e-06
Identities = 58/240 (24%), Positives = 89/240 (37%), Gaps = 17/240 (7%)
Query: 121 DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAAS---CTAEGSP 177
D G Y C V+ AG + +RVLVPP+ EE L ++ C + GSP
Sbjct: 2842 DAGRYTC-VAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSP 2900
Query: 178 APSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRIT 237
AP +W + + K + + ++ ++ + CV + +
Sbjct: 2901 APRNSWQKDGQPLLEDDHHKFLSNGRI---LQILNTQITDIGRYVCVAENTAGSAKKYFN 2957
Query: 238 HILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPLPSGVRV-- 295
+HV SV G + +NL + L C G PPP +W + + P+
Sbjct: 2958 LNVHVP----PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI 3013
Query: 296 --DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVSASVVVV 353
G TL G Y C N+ + ++ V P S K D S SVV V
Sbjct: 3014 VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP--PSIKDHDSESLSVVNV 3071
Score = 49.3 bits (116), Expect = 8e-06
Identities = 60/231 (25%), Positives = 95/231 (41%), Gaps = 18/231 (7%)
Query: 110 GSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGP-ALEEGQGLTLA 168
G ++L N V D G Y C V+ AG + L V V P + PG +L +G+ L L
Sbjct: 4222 GELILENVVLEDSGFYTC-VANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRL- 4279
Query: 169 ASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228
SC A G P P +TW T + + + +V LV R T V +
Sbjct: 4280 -SCKATGIPLPKLTW-------TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAE 4331
Query: 229 GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREG-AMLKCLSEGQPPPSYNWTR--L 285
+ + ++V E V + + W G A+L C +G P P+ W R +
Sbjct: 4332 NSVGFVKAIGFVYVK---EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGV 4388
Query: 286 DGPLPSGVRVDGD-TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
D + +R G+ +L E +G Y C +NE + +++ + P
Sbjct: 4389 DIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSP 4439
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/237 (23%), Positives = 96/237 (40%), Gaps = 24/237 (10%)
Query: 117 AVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEE---GQGLTLAASCTA 173
A ++D Y C V++ AG+ + L+V + P + N G E +G +++ C
Sbjct: 2259 AEKSDAALYSC-VASNVAGTAKKEYNLQVYIRPTIT-NSGSHPTEIIVTRGKSISLECEV 2316
Query: 174 EGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQP---LTCVVSHPGL 230
+G P P+VTW ++ + E H++ ++++ CV +
Sbjct: 2317 QGIPPPTVTW------MKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Query: 231 LQDQRITHILHVSFLAEASVRG--LEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGP 288
+ D++ +H A S+ G +N+ + + L C + G P PS W + P
Sbjct: 2371 MTDKKYDLSVH----APPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWP 2426
Query: 289 --LPSGVRV--DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGK 341
L + VR+ G L T E +G Y C V N + VL P G+
Sbjct: 2427 VSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGE 2483
Score = 48.5 bits (114), Expect = 1e-05
Identities = 78/328 (23%), Positives = 125/328 (38%), Gaps = 49/328 (14%)
Query: 37 SDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEG 96
++ +TV+ G + C G +AW R Q L L H++ + G
Sbjct: 3442 TEEITVLKGSSTSMACI---TDGTPAPSMAWLR-----DGQPLGL-----DAHLTVSTHG 3488
Query: 97 RVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPG 156
V Q L A D G+Y C +++ AG L+VL PP +N
Sbjct: 3489 MVLQ-------------LLKAETEDSGKYTC-IASNEAGEVSKHFILKVLEPP--HINGS 3532
Query: 157 PALEEGQGLT---LAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPS 213
EE + L +C A G PAP +TW + + + + V + +
Sbjct: 3533 EEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEV---LRISTA 3589
Query: 214 RSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGL-EDQNLWHIGREGAMLKCLS 272
+ + TC+ S P D+ +HV ++ G E +++ + L+C S
Sbjct: 3590 QVEDTGRYTCLASSPAGDDDKEYLVRVHV----PPNIAGTDEPRDITVLRNRQVTLECKS 3645
Query: 273 EGQPPPSYNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSN--EFSSRDS 326
+ PPP W R L + RV G L + Y C SN ++R+
Sbjct: 3646 DAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREF 3705
Query: 327 QVTVDVLDPQEDSGKQ--VDLVSASVVV 352
+TV+V P G Q V L++ S V+
Sbjct: 3706 ILTVNV-PPNIKGGPQSLVILLNKSTVL 3732
Score = 47.4 bits (111), Expect = 3e-05
Identities = 57/247 (23%), Positives = 96/247 (38%), Gaps = 24/247 (9%)
Query: 109 DGSVLLRNAVQA-DEGEYECRVSTFPAGSFQARLRLRVLVPPLPS-----LNPGPALEEG 162
DG++L+ +V D GEY C V+ AG+ + + L+V VPP+ N L +
Sbjct: 1319 DGTLLVIASVTPYDNGEYIC-VAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQL 1377
Query: 163 QGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLT 222
L C EG+P+P + W + T S + + + + F P + G+
Sbjct: 1378 TNLF----CEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDA--GRYSC 1431
Query: 223 CVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQN-LWHIGREGAMLKCLSEGQPPPSYN 281
++ G Q ++ L ++ G N + + L+C +G P P +
Sbjct: 1432 KAINIAGTSQ-----KYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIH 1486
Query: 282 WTRLDGPL----PSGVRVD-GDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQ 336
W + PL P+ +D G L G Y C VSN + + + + P
Sbjct: 1487 WFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPP 1546
Query: 337 EDSGKQV 343
G V
Sbjct: 1547 SIKGGNV 1553
Score = 46.6 bits (109), Expect = 5e-05
Identities = 50/233 (21%), Positives = 84/233 (36%), Gaps = 17/233 (7%)
Query: 120 ADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEE---GQGLTLAASCTAEGS 176
+D GEY C ++ AG + + L V VPP + +L +G +++ C +
Sbjct: 3028 SDGGEYTC-IAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAV 3086
Query: 177 PAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRI 236
P P +TW + T S H A H+ + + C + D+
Sbjct: 3087 PPPVITWYKNGRMITEST---HVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNF 3143
Query: 237 THILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNW----TRLDGPLPSG 292
H++ S+ G E + + L C + G PPP+ W R++
Sbjct: 3144 ----HLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLE 3199
Query: 293 VRV--DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQV 343
VR+ G L SG Y C SN + + P +G ++
Sbjct: 3200 VRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEI 3252
Score = 46.6 bits (109), Expect = 5e-05
Identities = 35/125 (28%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 109 DGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLA 168
+GS+ + V D G+Y C V+T AG + + L + PP+ +L P + G +
Sbjct: 4401 NGSLAIYGTVNEDAGDYTC-VATNEAGVVERSMSLTLQSPPIITLEPVETVINAGG-KII 4458
Query: 169 ASCTAEGSPAPSVT---------WDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQ 219
+C A G P P++T WD V +++ + TSEF V +R++ G
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECV-ARNLMGS 4517
Query: 220 PLTCV 224
L V
Sbjct: 4518 VLVRV 4522
Score = 44.7 bits (104), Expect = 2e-04
Identities = 53/244 (21%), Positives = 94/244 (38%), Gaps = 11/244 (4%)
Query: 114 LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP-LPSLNPGPALEEGQGLTLAASCT 172
+ +A D G Y C +T AG + + + VPP + + L +G ++ C
Sbjct: 2161 IEDAQVQDTGRYTCE-ATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCE 2219
Query: 173 AEGSPAPSVTWDTEVKGT-TSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLL 231
+ G P P++ W + KG+ + S R + + + + + +CV S+ +
Sbjct: 2220 SSGIPPPNLIW--KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASN--VA 2275
Query: 232 QDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTRLDGPL-- 289
+ + L V + G + + L+C +G PPP+ W + PL
Sbjct: 2276 GTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIK 2335
Query: 290 PSGVRV--DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQEDSGKQVDLVS 347
GV + +G L + +G YVC N D + + V P G +
Sbjct: 2336 AKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2395
Query: 348 ASVV 351
SVV
Sbjct: 2396 ISVV 2399
Score = 43.5 bits (101), Expect = 5e-04
Identities = 55/236 (23%), Positives = 96/236 (40%), Gaps = 23/236 (9%)
Query: 110 GSVLLRNAVQA-DEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPA-LEEGQGLTL 167
G VL + Q D G Y C S+ PAG +RV VPP + P + + +
Sbjct: 3581 GEVLRISTAQVEDTGRYTCLASS-PAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQV 3639
Query: 168 AASCTAEGSPAPSVTW---DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCV 224
C ++ P P +TW ++ T R R + + + + TCV
Sbjct: 3640 TLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINN------ADLGDTANYTCV 3693
Query: 225 VSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTR 284
S+ + T ++ +++G Q+L + + +L+C++EG P P W R
Sbjct: 3694 ASNIA----GKTTREFILTVNVPPNIKG-GPQSLVILLNKSTVLECIAEGVPTPRITW-R 3747
Query: 285 LDGPLPSGVRVDGDTL--GFPPLTTEH---SGIYVCHVSNEFSSRDSQVTVDVLDP 335
DG + +G L GF + + H +G Y+C +N + ++ + V P
Sbjct: 3748 KDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP 3803
Score = 43.1 bits (100), Expect = 6e-04
Identities = 57/237 (24%), Positives = 90/237 (37%), Gaps = 28/237 (11%)
Query: 110 GSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAA 169
GS+++ + D YEC V T AG + + L V VPP + P L +
Sbjct: 3859 GSLVIISPSVDDTATYECTV-TNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVI- 3916
Query: 170 SCTAEGSPAPSVTWDTE-VKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHP 228
+CTA G P PS+ W ++ ++ S A+ ++ ++ + TCV +
Sbjct: 3917 TCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAI----EILATQLNHAGRYTCVARNA 3972
Query: 229 GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWT----- 283
+ +T LHV E V + L I +L C + G P P W
Sbjct: 3973 AGSAHRHVT--LHVH---EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGIN 4027
Query: 284 -----RLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
R LPSG L E +G Y+C N + ++ ++V P
Sbjct: 4028 VNTSGRNHAVLPSG------GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVP 4078
Score = 42.7 bits (99), Expect = 8e-04
Identities = 57/240 (23%), Positives = 89/240 (37%), Gaps = 21/240 (8%)
Query: 108 LDGSVLLR--NAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPL---PSLNPGPALEEG 162
L G +LR D G+Y C V AG + L VLVPP + ++E
Sbjct: 2436 LSGGRMLRLMQTTMEDAGQYTCVVRN-AAGEERKIFGLSVLVPPHIVGENTLEDVKVKEK 2494
Query: 163 QGLTLAASCTAEGSPAPSVTWDTE---VKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQ 219
Q +TL +C G+P P +TW + ++ + R +T+ VP
Sbjct: 2495 QSVTL--TCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNV--QVPHTGR--- 2547
Query: 220 PLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPS 279
TC+ S P + + + + VS +++ I L C + PP +
Sbjct: 2548 -YTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPAT 2606
Query: 280 YNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP 335
W + PL S + G TL +++G Y C +NE V V P
Sbjct: 2607 ITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIP 2666
Score = 41.6 bits (96), Expect = 0.002
Identities = 56/241 (23%), Positives = 95/241 (39%), Gaps = 21/241 (8%)
Query: 106 NPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPP-LPSLNPG---PALEE 161
NP DG++ + A +D G Y C V+T AG+ + + L V PP + L P E
Sbjct: 1221 NP-DGTLSIDQATPSDAGIYTC-VATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQER 1278
Query: 162 GQGLTLAASCTAEGSPAPSVTW---DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNG 218
+ C A+G+P P++ W E+ G S + V + + NG
Sbjct: 1279 VANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASV----TPYDNG 1334
Query: 219 QPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPP 278
+ + V+ G +++ +HV + + + N+ + + L C EG P P
Sbjct: 1335 EYICVAVNEAG-TTERKYNLKVHVPPVIKDKE---QVTNVSVLLNQLTNLFCEVEGTPSP 1390
Query: 279 SYNWTRLDGPLPSGVRV----DGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD 334
W + + + + +G L T E +G Y C N + +DVL
Sbjct: 1391 IIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLV 1450
Query: 335 P 335
P
Sbjct: 1451 P 1451
Score = 41.6 bits (96), Expect = 0.002
Identities = 59/245 (24%), Positives = 95/245 (38%), Gaps = 23/245 (9%)
Query: 97 RVEQPPPPRNPLDGSVL-LRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNP 155
R++ P R G L + NA D Y C S AG L V VPP ++
Sbjct: 3661 RLQATPRVRILSGGRYLQINNADLGDTANYTCVASNI-AGKTTREFILTVNVPP--NIKG 3717
Query: 156 GP-ALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEF-HLVPS 213
GP +L + C AEG P P +TW + + + H+R + + + F H+ +
Sbjct: 3718 GPQSLVILLNKSTVLECIAEGVPTPRITW----RKDGAVLAGNHARYSILENGFLHIQSA 3773
Query: 214 RSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSE 273
+ C+ ++ +RI +HV N+ I L C +
Sbjct: 3774 HVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPG-----PTNMTVIVNVQTTLACEAT 3828
Query: 274 GQPPPSYNWTR------LDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQ 327
G P PS NW + +D S + +L + + + Y C V+N + D +
Sbjct: 3829 GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN--GAGDDK 3886
Query: 328 VTVDV 332
TVD+
Sbjct: 3887 RTVDL 3891
Score = 36.6 bits (83), Expect = 0.056
Identities = 52/246 (21%), Positives = 85/246 (34%), Gaps = 29/246 (11%)
Query: 112 VLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASC 171
+++ A ++ G Y C + AG + + V VPP + + +A C
Sbjct: 1790 LVIAQAQVSNTGLYRCMAAN-TAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQC 1848
Query: 172 TAEGSPAPSVTW-DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGL 230
A G P PS+TW + T+ + K S V + + + TCV ++
Sbjct: 1849 IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV---LQIAKTLLEDAGRYTCVATNAAG 1905
Query: 231 LQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSYNWTR----LD 286
Q I +H E + + L + L L+C + G P P W + L
Sbjct: 1906 ETQQHIQLHVHEPPSLEDAGKMLNETVL---VSNPVQLECKAAGNPVPVITWYKDNRLLS 1962
Query: 287 GPLPSGVRVDGDTLGFPPLTTEHSGIYVC-----------------HVSNEFSSRDSQVT 329
G G + +GIY C HV+ S ++ V
Sbjct: 1963 GSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVA 2022
Query: 330 VDVLDP 335
V V +P
Sbjct: 2023 VVVNNP 2028
>gi|145275174 kin of IRRE-like 2 isoform c [Homo sapiens]
Length = 708
Score = 63.2 bits (152), Expect = 6e-10
Identities = 80/328 (24%), Positives = 126/328 (38%), Gaps = 39/328 (11%)
Query: 18 LLLLLASFTGRCPAGE--LETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEG 75
LL+LL F GR L+ + + V+LG++A+LPC G G V W + G
Sbjct: 9 LLVLLFCFRGRAGPSPHFLQQPEDLVVLLGEEARLPCAL----GAYWGLVQWTKSGLALG 64
Query: 76 AQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAG 135
Q S+Y + + A G+ + + +R DE YEC+ + AG
Sbjct: 65 GQRDLPGWSRYWISGNAA-NGQHD------------LHIRPVELEDEASYECQAT--QAG 109
Query: 136 SFQARLRLRVLVPP-LPSLNPGPALEEGQGLTLAASCTAEGS--PAPSVTWDTE---VKG 189
+L VLVPP P + GP++ G+ +C + G P P + W + + G
Sbjct: 110 LRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRGDARPTPELLWFRDGVLLDG 169
Query: 190 TTSSRS-FKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEA 248
T ++ K +V S L P +G C L + L + + E
Sbjct: 170 ATFHQTLLKEGTPGSVESTLTLTPFSHDDGATFVCRARSQALPTGRDTAITLSLQYPPEV 229
Query: 249 SVRGLEDQNLWHIGREG--AMLKCLSEGQPP-PSYNWTRLDGPLPSGVRVDGDTLGFPPL 305
++ H +EG + C + QPP Y W + P+ + +
Sbjct: 230 TLSASP-----HTVQEGEKVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADASF 284
Query: 306 TTEHSGIYVCHVSNEFSSRDSQVTVDVL 333
TE C VSN S + +DVL
Sbjct: 285 LTEPVS---CEVSNAVGSANRSTALDVL 309
Score = 40.8 bits (94), Expect = 0.003
Identities = 71/281 (25%), Positives = 100/281 (35%), Gaps = 44/281 (15%)
Query: 40 VTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVE 99
V++V G A L C RGD+ ++ W R + A H +P G VE
Sbjct: 134 VSLVAGVPANLTCRSRGDA-RPTPELLWFRDGV---LLDGATFHQTLLKEGTP---GSVE 186
Query: 100 QPPPPRNPLDGSVLLRNAVQADEGE-YECRVST--FPAGSFQARLRLRVLVPPLPSLNPG 156
S L D+G + CR + P G A + L + PP +L+
Sbjct: 187 -----------STLTLTPFSHDDGATFVCRARSQALPTGRDTA-ITLSLQYPPEVTLSAS 234
Query: 157 P-ALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRS 215
P ++EG+ + TA+ P VT KG + + R +V S
Sbjct: 235 PHTVQEGEKVIFLCQATAQ----PPVTGYRWAKGGSPVLGARGPR-------LEVVADAS 283
Query: 216 MNGQPLTCVVSHP-GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEG 274
+P++C VS+ G +L L D E A C G
Sbjct: 284 FLTEPVSCEVSNAVGSANRSTALDVLFGPILQAKPEPVSVDVG------EDASFSCAWRG 337
Query: 275 QPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVC 315
P P WTR G G G TL P + E +G YVC
Sbjct: 338 NPLPRVTWTRRGGAQVLG---SGATLRLPSVGPEDAGDYVC 375
>gi|145275170 kin of IRRE-like 2 isoform a [Homo sapiens]
Length = 633
Score = 63.2 bits (152), Expect = 6e-10
Identities = 80/328 (24%), Positives = 126/328 (38%), Gaps = 39/328 (11%)
Query: 18 LLLLLASFTGRCPAGE--LETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEG 75
LL+LL F GR L+ + + V+LG++A+LPC G G V W + G
Sbjct: 9 LLVLLFCFRGRAGPSPHFLQQPEDLVVLLGEEARLPCAL----GAYWGLVQWTKSGLALG 64
Query: 76 AQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECRVSTFPAG 135
Q S+Y + + A G+ + + +R DE YEC+ + AG
Sbjct: 65 GQRDLPGWSRYWISGNAA-NGQHD------------LHIRPVELEDEASYECQAT--QAG 109
Query: 136 SFQARLRLRVLVPP-LPSLNPGPALEEGQGLTLAASCTAEGS--PAPSVTWDTE---VKG 189
+L VLVPP P + GP++ G+ +C + G P P + W + + G
Sbjct: 110 LRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRGDARPTPELLWFRDGVLLDG 169
Query: 190 TTSSRS-FKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILHVSFLAEA 248
T ++ K +V S L P +G C L + L + + E
Sbjct: 170 ATFHQTLLKEGTPGSVESTLTLTPFSHDDGATFVCRARSQALPTGRDTAITLSLQYPPEV 229
Query: 249 SVRGLEDQNLWHIGREG--AMLKCLSEGQPP-PSYNWTRLDGPLPSGVRVDGDTLGFPPL 305
++ H +EG + C + QPP Y W + P+ + +
Sbjct: 230 TLSASP-----HTVQEGEKVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADASF 284
Query: 306 TTEHSGIYVCHVSNEFSSRDSQVTVDVL 333
TE C VSN S + +DVL
Sbjct: 285 LTEPVS---CEVSNAVGSANRSTALDVL 309
Score = 40.8 bits (94), Expect = 0.003
Identities = 71/281 (25%), Positives = 100/281 (35%), Gaps = 44/281 (15%)
Query: 40 VTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVE 99
V++V G A L C RGD+ ++ W R + A H +P G VE
Sbjct: 134 VSLVAGVPANLTCRSRGDA-RPTPELLWFRDGV---LLDGATFHQTLLKEGTP---GSVE 186
Query: 100 QPPPPRNPLDGSVLLRNAVQADEGE-YECRVST--FPAGSFQARLRLRVLVPPLPSLNPG 156
S L D+G + CR + P G A + L + PP +L+
Sbjct: 187 -----------STLTLTPFSHDDGATFVCRARSQALPTGRDTA-ITLSLQYPPEVTLSAS 234
Query: 157 P-ALEEGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRS 215
P ++EG+ + TA+ P VT KG + + R +V S
Sbjct: 235 PHTVQEGEKVIFLCQATAQ----PPVTGYRWAKGGSPVLGARGPR-------LEVVADAS 283
Query: 216 MNGQPLTCVVSHP-GLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEG 274
+P++C VS+ G +L L D E A C G
Sbjct: 284 FLTEPVSCEVSNAVGSANRSTALDVLFGPILQAKPEPVSVDVG------EDASFSCAWRG 337
Query: 275 QPPPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVC 315
P P WTR G G G TL P + E +G YVC
Sbjct: 338 NPLPRVTWTRRGGAQVLG---SGATLRLPSVGPEDAGDYVC 375
>gi|61742797 basal cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 588
Score = 61.6 bits (148), Expect = 2e-09
Identities = 92/383 (24%), Positives = 139/383 (36%), Gaps = 34/383 (8%)
Query: 2 PLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQ 61
P A+ G LLL +LLA+ L +V V+ G+ L C G
Sbjct: 3 PPDAPAQARGAPRLLLLAVLLAAHPDAQAEVRLSVPPLVEVMRGKSVILDCTPTGTHDHY 62
Query: 62 VGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQAD 121
+ + W D LA + G + + PP + G ++L A D
Sbjct: 63 M--LEWFLTDRSGARPRLASAEMQ-GSELQVTMHDTRGRSPPYQLDSQGRLVLAEAQVGD 119
Query: 122 EGEYECRVSTFPAGSFQARLRLRVLVPPLP---SLNPGP-ALEEGQGLTLAASCTAEGSP 177
E +Y C V AG+ +A RL V P S N G ++ E +A + G+P
Sbjct: 120 ERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCNSRNGNP 179
Query: 178 APSVTW-----------DTEVKGTTSSRSFKH-SRSAAVTSEFHLVPSRSMNGQPLTCVV 225
AP +TW + +G +SR+ + S ++TS +L + C
Sbjct: 180 APKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKDDRDASFHCAA 239
Query: 226 SHP------GLLQDQRITHILHV-SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPP 278
+ G L LH + + V W + L C +G P P
Sbjct: 240 HYSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQLLCRGDGSPSP 299
Query: 279 SYNWTRLDGPLPSGVRVDGD-TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVT------VD 331
Y RL + V+ + L +T SG Y C V + ++ D Q++ V
Sbjct: 300 EYTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVA 359
Query: 332 VLDPQE-DSGKQVDLVSASVVVV 353
LDP E GK + L S VV
Sbjct: 360 YLDPLELSEGKVLSLPLNSSAVV 382
Score = 52.0 bits (123), Expect = 1e-06
Identities = 61/268 (22%), Positives = 103/268 (38%), Gaps = 26/268 (9%)
Query: 108 LDGSVLLRNAVQADEGEYECRVSTFPAG---SFQARLRLRVLVPPLPSLNPGPALEEGQG 164
L+G++ L + G Y CRV + A L LRV L+ G L
Sbjct: 318 LEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLN 377
Query: 165 LTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCV 224
+ +C+ G P P++ W K +T +++T + NG C
Sbjct: 378 SSAVVNCSVHGLPTPALRW---TKDSTPLGDGPMLSLSSITFD--------SNG-TYVCE 425
Query: 225 VSHPG---LLQDQRITHILHVS-FLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSY 280
S P L + Q T ++ S L A + D + W G E ++ C + G P P
Sbjct: 426 ASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGS-WREGDEVTLI-CSARGHPDPKL 483
Query: 281 NWTRLDG----PLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQ 336
+W++L G P+P +L + C SN ++ + PQ
Sbjct: 484 SWSQLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTVSPQ 543
Query: 337 -EDSGKQVDLVSASVVVVGVIAALLFCL 363
+G V V+ SV ++ ++ A+ +C+
Sbjct: 544 TSQAGVAVMAVAVSVGLLLLVVAVFYCV 571
Score = 37.0 bits (84), Expect = 0.043
Identities = 38/158 (24%), Positives = 57/158 (36%), Gaps = 15/158 (9%)
Query: 163 QGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLT 222
+G T+ C +GSP+P T + V E +L GQ T
Sbjct: 283 EGDTVQLLCRGDGSPSPEYT--------LFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGT 334
Query: 223 --CVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSY 280
C V D +++ L + + E + L A++ C G P P+
Sbjct: 335 YGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPAL 394
Query: 281 NWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVS 318
WT+ PL DG L +T + +G YVC S
Sbjct: 395 RWTKDSTPLG-----DGPMLSLSSITFDSNGTYVCEAS 427
>gi|31543106 basal cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 628
Score = 61.6 bits (148), Expect = 2e-09
Identities = 92/383 (24%), Positives = 139/383 (36%), Gaps = 34/383 (8%)
Query: 2 PLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQ 61
P A+ G LLL +LLA+ L +V V+ G+ L C G
Sbjct: 3 PPDAPAQARGAPRLLLLAVLLAAHPDAQAEVRLSVPPLVEVMRGKSVILDCTPTGTHDHY 62
Query: 62 VGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQAD 121
+ + W D LA + G + + PP + G ++L A D
Sbjct: 63 M--LEWFLTDRSGARPRLASAEMQ-GSELQVTMHDTRGRSPPYQLDSQGRLVLAEAQVGD 119
Query: 122 EGEYECRVSTFPAGSFQARLRLRVLVPPLP---SLNPGP-ALEEGQGLTLAASCTAEGSP 177
E +Y C V AG+ +A RL V P S N G ++ E +A + G+P
Sbjct: 120 ERDYVCVVRAGAAGTAEATARLNVFAKPEATEVSPNKGTLSVMEDSAQEIATCNSRNGNP 179
Query: 178 APSVTW-----------DTEVKGTTSSRSFKH-SRSAAVTSEFHLVPSRSMNGQPLTCVV 225
AP +TW + +G +SR+ + S ++TS +L + C
Sbjct: 180 APKITWYRNGQRLEVPVEMNPEGYMTSRTVREASGLLSLTSTLYLRLRKDDRDASFHCAA 239
Query: 226 SHP------GLLQDQRITHILHV-SFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPP 278
+ G L LH + + V W + L C +G P P
Sbjct: 240 HYSLPEGRHGRLDSPTFHLTLHYPTEHVQFWVGSPSTPAGWVREGDTVQLLCRGDGSPSP 299
Query: 279 SYNWTRLDGPLPSGVRVDGD-TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVT------VD 331
Y RL + V+ + L +T SG Y C V + ++ D Q++ V
Sbjct: 300 EYTLFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVA 359
Query: 332 VLDPQE-DSGKQVDLVSASVVVV 353
LDP E GK + L S VV
Sbjct: 360 YLDPLELSEGKVLSLPLNSSAVV 382
Score = 52.0 bits (123), Expect = 1e-06
Identities = 61/268 (22%), Positives = 103/268 (38%), Gaps = 26/268 (9%)
Query: 108 LDGSVLLRNAVQADEGEYECRVSTFPAG---SFQARLRLRVLVPPLPSLNPGPALEEGQG 164
L+G++ L + G Y CRV + A L LRV L+ G L
Sbjct: 318 LEGNLTLEGVTRGQSGTYGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLN 377
Query: 165 LTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCV 224
+ +C+ G P P++ W K +T +++T + NG C
Sbjct: 378 SSAVVNCSVHGLPTPALRW---TKDSTPLGDGPMLSLSSITFD--------SNG-TYVCE 425
Query: 225 VSHPG---LLQDQRITHILHVS-FLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSY 280
S P L + Q T ++ S L A + D + W G E ++ C + G P P
Sbjct: 426 ASLPTVPVLSRTQNFTLLVQGSPELKTAEIEPKADGS-WREGDEVTLI-CSARGHPDPKL 483
Query: 281 NWTRLDG----PLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDPQ 336
+W++L G P+P +L + C SN ++ + PQ
Sbjct: 484 SWSQLGGSPAEPIPGRQGWVSSSLTLKVTSALSRDGISCEASNPHGNKRHVFHFGTVSPQ 543
Query: 337 -EDSGKQVDLVSASVVVVGVIAALLFCL 363
+G V V+ SV ++ ++ A+ +C+
Sbjct: 544 TSQAGVAVMAVAVSVGLLLLVVAVFYCV 571
Score = 37.0 bits (84), Expect = 0.043
Identities = 38/158 (24%), Positives = 57/158 (36%), Gaps = 15/158 (9%)
Query: 163 QGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLT 222
+G T+ C +GSP+P T + V E +L GQ T
Sbjct: 283 EGDTVQLLCRGDGSPSPEYT--------LFRLQDEQEEVLNVNLEGNLTLEGVTRGQSGT 334
Query: 223 --CVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQPPPSY 280
C V D +++ L + + E + L A++ C G P P+
Sbjct: 335 YGCRVEDYDAADDVQLSKTLELRVAYLDPLELSEGKVLSLPLNSSAVVNCSVHGLPTPAL 394
Query: 281 NWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVS 318
WT+ PL DG L +T + +G YVC S
Sbjct: 395 RWTKDSTPLG-----DGPMLSLSSITFDSNGTYVCEAS 427
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,096,348
Number of Sequences: 37866
Number of extensions: 1201284
Number of successful extensions: 6134
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 134
Number of HSP's successfully gapped in prelim test: 299
Number of HSP's that attempted gapping in prelim test: 4105
Number of HSP's gapped (non-prelim): 1679
length of query: 510
length of database: 18,247,518
effective HSP length: 107
effective length of query: 403
effective length of database: 14,195,856
effective search space: 5720929968
effective search space used: 5720929968
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.