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Search of human proteins with 221139926
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221139926 NHS-like 1 [Homo sapiens]
(1606 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221139926 NHS-like 1 [Homo sapiens] 3246 0.0
gi|38093637 Nance-Horan syndrome protein isoform 1 [Homo sapiens] 418 e-116
gi|209862849 Nance-Horan syndrome protein isoform 2 [Homo sapiens] 414 e-115
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 120 1e-26
gi|163965366 nascent polypeptide-associated complex alpha subuni... 101 5e-21
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 96 4e-19
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 96 4e-19
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 96 4e-19
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 94 1e-18
gi|116284392 mucin 2 precursor [Homo sapiens] 93 2e-18
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 92 3e-18
gi|47132519 Ras association and pleckstrin homology domains 1 is... 91 1e-17
gi|153792074 proline rich 12 [Homo sapiens] 90 2e-17
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 87 2e-16
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 85 6e-16
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 85 6e-16
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 85 6e-16
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 85 6e-16
gi|11386183 WAS protein family, member 2 [Homo sapiens] 84 1e-15
gi|91982772 mucin 17 [Homo sapiens] 83 2e-15
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 82 3e-15
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 82 4e-15
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 82 5e-15
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 80 1e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 80 2e-14
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 80 2e-14
gi|146134388 YLP motif containing 1 [Homo sapiens] 79 4e-14
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 79 5e-14
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 79 5e-14
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 79 5e-14
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 3246 bits (8415), Expect = 0.0
Identities = 1606/1606 (100%), Positives = 1606/1606 (100%)
Query: 1 MVVFINAKIKSLIKLFKKKTVSNLDEESRWTVHYTAPWHQQENVFLPTTRPPCVEDLHRQ 60
MVVFINAKIKSLIKLFKKKTVSNLDEESRWTVHYTAPWHQQENVFLPTTRPPCVEDLHRQ
Sbjct: 1 MVVFINAKIKSLIKLFKKKTVSNLDEESRWTVHYTAPWHQQENVFLPTTRPPCVEDLHRQ 60
Query: 61 AKLNLKSVLRECDKLRHDGYRSSQYYSQGPTFAANASPFCDDYQDEDEETDQKCSLSSSE 120
AKLNLKSVLRECDKLRHDGYRSSQYYSQGPTFAANASPFCDDYQDEDEETDQKCSLSSSE
Sbjct: 61 AKLNLKSVLRECDKLRHDGYRSSQYYSQGPTFAANASPFCDDYQDEDEETDQKCSLSSSE 120
Query: 121 EERFISIRRPKTPASSDFSDLNTQTNWTKSLPLPTPEEKMRQQAQTVQADVVPINITGEN 180
EERFISIRRPKTPASSDFSDLNTQTNWTKSLPLPTPEEKMRQQAQTVQADVVPINITGEN
Sbjct: 121 EERFISIRRPKTPASSDFSDLNTQTNWTKSLPLPTPEEKMRQQAQTVQADVVPINITGEN 180
Query: 181 FDRQASLRRSLIYTDTLVRRPKKVKRRKTITGVPDNIQKELASGTGQDDADGHSVYTPDH 240
FDRQASLRRSLIYTDTLVRRPKKVKRRKTITGVPDNIQKELASGTGQDDADGHSVYTPDH
Sbjct: 181 FDRQASLRRSLIYTDTLVRRPKKVKRRKTITGVPDNIQKELASGTGQDDADGHSVYTPDH 240
Query: 241 YSTLGRFNSCRSAGQRSETRDSSCQTEDVKVVPPSMRRIRAQKGQGIAAQMGHFSGSSGN 300
YSTLGRFNSCRSAGQRSETRDSSCQTEDVKVVPPSMRRIRAQKGQGIAAQMGHFSGSSGN
Sbjct: 241 YSTLGRFNSCRSAGQRSETRDSSCQTEDVKVVPPSMRRIRAQKGQGIAAQMGHFSGSSGN 300
Query: 301 MSVLSDSAGIVFPSRLDSDAGFHSLPRSGARANIQSLEPRLGALGPAGDMNGTFLYQRGH 360
MSVLSDSAGIVFPSRLDSDAGFHSLPRSGARANIQSLEPRLGALGPAGDMNGTFLYQRGH
Sbjct: 301 MSVLSDSAGIVFPSRLDSDAGFHSLPRSGARANIQSLEPRLGALGPAGDMNGTFLYQRGH 360
Query: 361 PQADENLGHLGGASGTGTLLRPKSQELRHFESENIMSPACVVSPHATYSTSIIPNATLSS 420
PQADENLGHLGGASGTGTLLRPKSQELRHFESENIMSPACVVSPHATYSTSIIPNATLSS
Sbjct: 361 PQADENLGHLGGASGTGTLLRPKSQELRHFESENIMSPACVVSPHATYSTSIIPNATLSS 420
Query: 421 SSEVIAIPTAQSAGQRESKSSGSSHARIKSRDHLISRHAVKGDPQSPGRHWNEGHATILS 480
SSEVIAIPTAQSAGQRESKSSGSSHARIKSRDHLISRHAVKGDPQSPGRHWNEGHATILS
Sbjct: 421 SSEVIAIPTAQSAGQRESKSSGSSHARIKSRDHLISRHAVKGDPQSPGRHWNEGHATILS 480
Query: 481 QDLDPHSPGEPALLSLCDSAVPLNAPANRENGSQAMPYNCRNNLAFPAHPQDVDGKSESS 540
QDLDPHSPGEPALLSLCDSAVPLNAPANRENGSQAMPYNCRNNLAFPAHPQDVDGKSESS
Sbjct: 481 QDLDPHSPGEPALLSLCDSAVPLNAPANRENGSQAMPYNCRNNLAFPAHPQDVDGKSESS 540
Query: 541 YSGGGGHSSSEPWEYKSSGNGRASPLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLY 600
YSGGGGHSSSEPWEYKSSGNGRASPLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLY
Sbjct: 541 YSGGGGHSSSEPWEYKSSGNGRASPLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLY 600
Query: 601 SEDHDGYCASVHTDSGHGSGNLCNSSDGFGNPRHSVINVFVGRAQKNQGDRSNYQDKSLS 660
SEDHDGYCASVHTDSGHGSGNLCNSSDGFGNPRHSVINVFVGRAQKNQGDRSNYQDKSLS
Sbjct: 601 SEDHDGYCASVHTDSGHGSGNLCNSSDGFGNPRHSVINVFVGRAQKNQGDRSNYQDKSLS 660
Query: 661 RNISLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSP 720
RNISLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSP
Sbjct: 661 RNISLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSP 720
Query: 721 SQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPW 780
SQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPW
Sbjct: 721 SQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPW 780
Query: 781 GYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPE 840
GYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPE
Sbjct: 781 GYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPE 840
Query: 841 KSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISS 900
KSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISS
Sbjct: 841 KSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISS 900
Query: 901 SSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCS 960
SSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCS
Sbjct: 901 SSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCS 960
Query: 961 QGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEP 1020
QGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEP
Sbjct: 961 QGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEP 1020
Query: 1021 PPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRP 1080
PPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRP
Sbjct: 1021 PPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRP 1080
Query: 1081 VRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPT 1140
VRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPT
Sbjct: 1081 VRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPT 1140
Query: 1141 PAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPK 1200
PAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPK
Sbjct: 1141 PAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPK 1200
Query: 1201 LFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGT 1260
LFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGT
Sbjct: 1201 LFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGT 1260
Query: 1261 SVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGV 1320
SVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGV
Sbjct: 1261 SVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGV 1320
Query: 1321 PETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRN 1380
PETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRN
Sbjct: 1321 PETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRN 1380
Query: 1381 HSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAE 1440
HSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAE
Sbjct: 1381 HSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAE 1440
Query: 1441 MLKNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRS 1500
MLKNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRS
Sbjct: 1441 MLKNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRS 1500
Query: 1501 RTPPSAASSRYSMRNRIQSSPMTVISEGEGEAVEPVDSIARGALGAAEGCSLDGLAREEM 1560
RTPPSAASSRYSMRNRIQSSPMTVISEGEGEAVEPVDSIARGALGAAEGCSLDGLAREEM
Sbjct: 1501 RTPPSAASSRYSMRNRIQSSPMTVISEGEGEAVEPVDSIARGALGAAEGCSLDGLAREEM 1560
Query: 1561 DEGGLLCGEGPAASLQPQAPGPVDGTASAEGREPSPQCGGSLSEES 1606
DEGGLLCGEGPAASLQPQAPGPVDGTASAEGREPSPQCGGSLSEES
Sbjct: 1561 DEGGLLCGEGPAASLQPQAPGPVDGTASAEGREPSPQCGGSLSEES 1606
>gi|38093637 Nance-Horan syndrome protein isoform 1 [Homo sapiens]
Length = 1630
Score = 418 bits (1075), Expect = e-116
Identities = 452/1605 (28%), Positives = 666/1605 (41%), Gaps = 274/1605 (17%)
Query: 21 VSNLDEESRWTVHYTAPWHQQENVFLPTTRPPCVEDLHRQAKLNLKSVLRECDKLRHDGY 80
VSNLD ES+ +V+Y APWHQQ N+FLP TRPPCVE+LHR A+ +L+++ RE + R D
Sbjct: 190 VSNLDIESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRHARQSLQALRRE-HRSRSD-- 246
Query: 81 RSSQYYSQGPTFAANASP-----------------FCDDYQDEDEETDQKCSLSSSEEER 123
R Q + + AA P F + EDE+TD
Sbjct: 247 RREQRAAAPLSIAAPPLPAYPPAHSQRRREFKDRHFLTSHPPEDEDTDVMLG-------- 298
Query: 124 FISIRRPKTPASSDFSDLNTQTNWTKSLPLPTPEEKMRQQAQTVQADVVPINITGENFDR 183
+RPK P + S L+ QTNW+K+LPLPTPEEKM+Q AQ + + ++PIN+TG FDR
Sbjct: 299 ----QRPKNPIHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISSCIIPINVTGVGFDR 354
Query: 184 QASLRRSLIYTDTLVRRPKKVKRRKTITGVPDNIQKELASGTGQDDADGHSVY--TPDHY 241
+AS+R SL+++ ++++R +K++RRKTI+G+P +Q+E+ S + + + PD
Sbjct: 355 EASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVARERNVIVHTNPDPS 414
Query: 242 STLGRFNSCRSAGQRSETRDSSCQTEDVKVVPPSMRRIRAQKGQGIAAQMGHFSGSSGNM 301
+T+ R S TRDS CQTED+ + PS RRIRAQ+GQ IAA + H S+GN+
Sbjct: 415 NTVNRI---------SGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSH---SAGNI 462
Query: 302 SVLSDSAGIVFPSRLDSDAGFHSLPRSGARANIQSLEPRLGALGPAGDMNGTFLYQRGHP 361
S L+D +F + S SLPR G R EP++GA A + +F+ H
Sbjct: 463 SALADKGDTMFTPAVSSRTRSRSLPREGNRGG--DAEPKVGAKPSAYEEGESFVGD--HE 518
Query: 362 QADENLGHLGGASGTGTLLRPKSQELRHFESENIMSPACVVSPHATYSTSIIPNATLSSS 421
+ + + P +Q+ + + AC H+ P LS
Sbjct: 519 RTPNDFSEAPSS--------PSAQD-----HQPTLGLACSQHLHS-------PQHKLSER 558
Query: 422 SEVIAIPTAQSAGQRESKSS----GSSHARIKSRDHLISRHA-VKGDPQSPGRHWNEGHA 476
A +G + S+ GS I + L+S H K D QS +W+ +
Sbjct: 559 GRSRLSRMAADSGSCDISSNSDTFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSS 618
Query: 477 TILSQDLDPHSPGEPALL---SLCDSAVPLN-APANRENGSQAMPYNCRNNLAFPAHPQD 532
T SQ + P L S CDS + LN AP E+ S + ++L
Sbjct: 619 TCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPHANEDASVFVTEQYNDHL------DK 672
Query: 533 VDGKSESSYSG---------GGGHSSSEPWEY-----KSSGNGRASPLKPHLATPGYSTP 578
V G +S++ ++S W Y +S SP +P + G +
Sbjct: 673 VRGHRANSFTSTVADLLDDPNNSNTSDSEWNYLHHHHDASCRQDFSPERPKADSLGCPSF 732
Query: 579 TSNMSSCSL--DQTSNKEDAGSLYSEDHDGYCASVHTDSG-HGSGNLCNSSDGFGNPRHS 635
TS + S S+K D S +S D +GY S+H D G G+ + G
Sbjct: 733 TSMATYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFDCGLKGNKSYVCHYAALGPENGQ 792
Query: 636 VINVFVGRAQKNQGDRSNYQDKSLSRNISLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQV 695
+ G D +++ + +IS +K K P PP R+ SLR K +
Sbjct: 793 GVGASPGLPDCAWQDYLDHKRQGRP-SISFRKPKAKPTPPKRSSSLR---KSDGNADISE 848
Query: 696 LNESLIATLQH----SLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSA 751
E I++ QH S ++ LP ++PS+ ++L P +QS A
Sbjct: 849 KKEPKISSGQHLPHSSREMKLPLDFANTPSRMENANLPTKQEPSWINQSEQGIKEPQLDA 908
Query: 752 TTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNG 811
+ P D + + Y D W + + T N
Sbjct: 909 SD---------IPPFKDEVAESTHYADLW---------------------LLNDLKT-ND 937
Query: 812 PVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKS 871
P R + S AT G +V I SPE S S +S S++ TP+ L V K
Sbjct: 938 PYRSLSNSSTAT-----GTTVIECIKSPESSE---SQTSQSESRATTPS-LPSVDNEFKL 988
Query: 872 VSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPP 931
SP G P SS S S T T T A S P P
Sbjct: 989 ASPEKLAGLASP----------------SSGYSSQSETPTSSFPT------AFFSGPLSP 1026
Query: 932 PPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLS 991
P P +R L P S P+ PP + S L+
Sbjct: 1027 GGSKRKPKVP---ERKSSLQQPSLKDGTISLSKDLELPIIPPTHLDL-----SALHNVLN 1078
Query: 992 PPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQP--ESSRG 1049
P P+ + L S+ PPP+ + P +K N + +
Sbjct: 1079 KPFHHRHPLHVFTHNKQNTVGETLRSN-PPPSLAITPTILKSVNLRSINKSEEVKQKEEN 1137
Query: 1050 SLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYH 1109
+ P +E T +TT AL ++RP N +E T A +
Sbjct: 1138 NTDLPYLEEST-------LTTAALSPSKIRPHTANKSVSRQYSTEDTILSFLDSSAVE-- 1188
Query: 1110 LKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSA 1169
+ P +NST ++++ P ++TS+ G + S
Sbjct: 1189 MGPDKLHLEKNSTFDVKNRCDPETITSA-------------------GSSLLDSNVTKDQ 1229
Query: 1170 GEAEARPSPSTTPLPDSS---------PSRKPPPISKKPKLFLVVPPPQKDFAVEPAENV 1220
E P P TP + + + +P + K ++ P D +E +
Sbjct: 1230 VRTETEPIPENTPTKNCAFPTEGFQRVSAARPNDLDGK----IIQYGPGPDETLEQVQKA 1285
Query: 1221 SEA-LRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGT-SVLEGGAAGSMSPSRVEA 1278
A L V P + + + S+ + A + H S G++S E+
Sbjct: 1286 PSAGLEEVAQPESVDV--ITSQSDSPTRATDVSNQFKHQFVMSRHHDKVPGTIS---YES 1340
Query: 1279 NVPMVQPDVSPAPKQEEPAEN-SADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLK 1337
+ V KQE A SA + D Q ++ S L
Sbjct: 1341 EITSVNSFPEKCSKQENIASGISAKSASDNSKAEETQGNVDEASLKESSPSDDSIISPLS 1400
Query: 1338 EDGNDEV----MTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAA 1393
ED E ++P++PRTTEDLFA IHRSKRKVLGR+DS D R+ S +P + + +A
Sbjct: 1401 EDSQAEAEGVFVSPNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRAPLSSSSSSA 1460
Query: 1394 PSLASP----------KQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLK 1443
S+ SP + G I R+ +KS+TS++ FK LLLKKGSRSD+S RMSA E+LK
Sbjct: 1461 SSITSPSSNVTTPNSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILK 1520
Query: 1444 NTDPRFQRSRSEPSPDAPESP----------------SSCSPSKNRRAQEEWAKNEGLMP 1487
+ P + E + ++P+S S CSP N EG
Sbjct: 1521 S--PILPKPPGELTAESPQSTDDAHQGSQGAEALSPLSPCSPRVNA---------EGFSS 1569
Query: 1488 RSLSFS-GPRYGRSRTPPSAASSRYSMRNRIQSSPMTVISEGEGE 1531
+S + S R GRSR PP+A+SSRYS+R R+ ++PM ISEGE E
Sbjct: 1570 KSFATSASARVGRSRAPPAASSSRYSVRCRLYNTPMQAISEGETE 1614
Score = 34.3 bits (77), Expect = 1.00
Identities = 26/75 (34%), Positives = 31/75 (41%), Gaps = 9/75 (12%)
Query: 951 PPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPL 1010
P P P D S GS P P+ PP L +P P PA + +P LP
Sbjct: 19 PAPGPAVDASGGSAEPPPPL-QPPGRRDLDEVEAP-----GPEEPARA---VPAPSGLPP 69
Query: 1011 PPPLLPSSEPPPAPP 1025
PPP LP+ PP
Sbjct: 70 PPPPLPAPADQTQPP 84
Score = 31.6 bits (70), Expect = 6.5
Identities = 24/76 (31%), Positives = 26/76 (34%), Gaps = 25/76 (32%)
Query: 986 PDWCLSPPRPALSPILPDSPVSLPLPPPL------------------------LPSSEPP 1021
P W RPA P + S S PPPL PS PP
Sbjct: 10 PQWLCRQRRPAPGPAVDASGGSAEPPPPLQPPGRRDLDEVEAPGPEEPARAVPAPSGLPP 69
Query: 1022 PAPPLDPKFMKDTRPP 1037
P PPL P T+PP
Sbjct: 70 PPPPL-PAPADQTQPP 84
>gi|209862849 Nance-Horan syndrome protein isoform 2 [Homo sapiens]
Length = 1474
Score = 414 bits (1063), Expect = e-115
Identities = 450/1627 (27%), Positives = 667/1627 (40%), Gaps = 289/1627 (17%)
Query: 17 KKKTVSNLDEESRWTVHYTAPWHQQENVFLPTTRPPCVEDLHRQAKLNLKSVLRE----- 71
K VSNLD ES+ +V+Y APWHQQ N+FLP TRPPCVE+LHR A+ +L+++ RE
Sbjct: 9 KNAAVSNLDIESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRHARQSLQALRREHRSRS 68
Query: 72 -----------------------CDKLRHDGYRSSQYY------SQGPTFAANASPFC-D 101
R ++ + S PT + +P+
Sbjct: 69 DRREQRAAAPLSIAAPPLPAYPPAHSQRRREFKDRHFLTFNSTRSPSPTECCHMTPWSRK 128
Query: 102 DYQDEDEETDQKCSLSSSEEERFISIRRPKTPASSDFSDLNTQTNWTKSLPLPTPEEKMR 161
+ EDE+TD +RPK P + S L+ QTNW+K+LPLPTPEEKM+
Sbjct: 129 SHPPEDEDTDVMLG------------QRPKNPIHNIPSTLDKQTNWSKALPLPTPEEKMK 176
Query: 162 QQAQTVQADVVPINITGENFDRQASLRRSLIYTDTLVRRPKKVKRRKTITGVPDNIQKEL 221
Q AQ + + ++PIN+TG FDR+AS+R SL+++ ++++R +K++RRKTI+G+P +Q+E+
Sbjct: 177 QDAQVISSCIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEI 236
Query: 222 ASGTGQDDADGHSVY--TPDHYSTLGRFNSCRSAGQRSETRDSSCQTEDVKVVPPSMRRI 279
S + + + PD +T+ R S TRDS CQTED+ + PS RRI
Sbjct: 237 DSDESPVARERNVIVHTNPDPSNTVNRI---------SGTRDSECQTEDILIAAPSRRRI 287
Query: 280 RAQKGQGIAAQMGHFSGSSGNMSVLSDSAGIVFPSRLDSDAGFHSLPRSGARANIQSLEP 339
RAQ+GQ IAA + H S+GN+S L+D +F + S SLPR G R EP
Sbjct: 288 RAQRGQSIAASLSH---SAGNISALADKGDTMFTPAVSSRTRSRSLPREGNRGG--DAEP 342
Query: 340 RLGALGPAGDMNGTFLYQRGHPQADENLGHLGGASGTGTLLRPKSQELRHFESENIMSPA 399
++GA A + +F+ H + + + P +Q+ + + A
Sbjct: 343 KVGAKPSAYEEGESFVGD--HERTPNDFSEAPSS--------PSAQD-----HQPTLGLA 387
Query: 400 CVVSPHATYSTSIIPNATLSSSSEVIAIPTAQSAGQRESKSS----GSSHARIKSRDHLI 455
C H+ P LS A +G + S+ GS I + L+
Sbjct: 388 CSQHLHS-------PQHKLSERGRSRLSRMAADSGSCDISSNSDTFGSPIHCISTAGVLL 440
Query: 456 SRHA-VKGDPQSPGRHWNEGHATILSQDLDPHSPGEPALL---SLCDSAVPLN-APANRE 510
S H K D QS +W+ +T SQ + P L S CDS + LN AP E
Sbjct: 441 SSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPHANE 500
Query: 511 NGSQAMPYNCRNNLAFPAHPQDVDGKSESSYSG---------GGGHSSSEPWEY-----K 556
+ S + ++L V G +S++ ++S W Y
Sbjct: 501 DASVFVTEQYNDHL------DKVRGHRANSFTSTVADLLDDPNNSNTSDSEWNYLHHHHD 554
Query: 557 SSGNGRASPLKPHLATPGYSTPTSNMSSCSL--DQTSNKEDAGSLYSEDHDGYCASVHTD 614
+S SP +P + G + TS + S S+K D S +S D +GY S+H D
Sbjct: 555 ASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFD 614
Query: 615 SG-HGSGNLCNSSDGFGNPRHSVINVFVGRAQKNQGDRSNYQDKSLSRNISLKKAKKPPL 673
G G+ + G + G D +++ + +IS +K K P
Sbjct: 615 CGLKGNKSYVCHYAALGPENGQGVGASPGLPDCAWQDYLDHKRQGRP-SISFRKPKAKPT 673
Query: 674 PPSRTDSLRRIPKKSSQCNGQVLNESLIATLQH----SLQLSLPGKSGSSPSQSPCSDLE 729
PP R+ SLR K + E I++ QH S ++ LP ++PS+ ++L
Sbjct: 674 PPKRSSSLR---KSDGNADISEKKEPKISSGQHLPHSSREMKLPLDFANTPSRMENANLP 730
Query: 730 EPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGM 789
P +QS A+ P D + + Y D W
Sbjct: 731 TKQEPSWINQSEQGIKEPQLDASD---------IPPFKDEVAESTHYADLW--------- 772
Query: 790 QEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPS 849
+ + T N P R + S AT G +V I SPE S S +
Sbjct: 773 ------------LLNDLKT-NDPYRSLSNSSTAT-----GTTVIECIKSPESSE---SQT 811
Query: 850 SGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSST 909
S S++ TP+ L V K SP G P SS S S T
Sbjct: 812 SQSESRATTPS-LPSVDNEFKLASPEKLAGLASP----------------SSGYSSQSET 854
Query: 910 STEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSP 969
T T A S P P P P +R L P S P
Sbjct: 855 PTSSFPT------AFFSGPLSPGGSKRKPKVP---ERKSSLQQPSLKDGTISLSKDLELP 905
Query: 970 VFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPK 1029
+ PP + S L+ P P+ + L S+ PPP+ + P
Sbjct: 906 IIPPTHLDL-----SALHNVLNKPFHHRHPLHVFTHNKQNTVGETLRSN-PPPSLAITPT 959
Query: 1030 FMKDTRPPFTNSGQP--ESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGA 1087
+K N + + + P +E T +TT AL ++RP N
Sbjct: 960 ILKSVNLRSINKSEEVKQKEENNTDLPYLEEST-------LTTAALSPSKIRPHTANKSV 1012
Query: 1088 EAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQ 1147
+E T A + + P +NST ++++ P ++TS+
Sbjct: 1013 SRQYSTEDTILSFLDSSAVE--MGPDKLHLEKNSTFDVKNRCDPETITSA---------- 1060
Query: 1148 GDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSS---------PSRKPPPISKK 1198
G + S E P P TP + + + +P + K
Sbjct: 1061 ---------GSSLLDSNVTKDQVRTETEPIPENTPTKNCAFPTEGFQRVSAARPNDLDGK 1111
Query: 1199 PKLFLVVPPPQKDFAVEPAENVSEA-LRAVPSPTTGEEGSVHSREAKESSAAQAGSHATH 1257
++ P D +E + A L V P + + + S+ + A + H
Sbjct: 1112 ----IIQYGPGPDETLEQVQKAPSAGLEEVAQPESVDV--ITSQSDSPTRATDVSNQFKH 1165
Query: 1258 PGT-SVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAEN-SADTGGDGESCLSQQD 1315
S G++S E+ + V KQE A SA + D Q
Sbjct: 1166 QFVMSRHHDKVPGTIS---YESEITSVNSFPEKCSKQENIASGISAKSASDNSKAEETQG 1222
Query: 1316 GAAGVPETNAAGSSSEACDFLKEDGNDEV----MTPSRPRTTEDLFAAIHRSKRKVLGRR 1371
++ S L ED E ++P++PRTTEDLFA IHRSKRKVLGR+
Sbjct: 1223 NVDEASLKESSPSDDSIISPLSEDSQAEAEGVFVSPNKPRTTEDLFAVIHRSKRKVLGRK 1282
Query: 1372 DSDDDHSRNHSPSPPVTPTGAAPSLASP----------KQVGSIQRSIRKSSTSSDNFKA 1421
DS D R+ S +P + + +A S+ SP + G I R+ +KS+TS++ FK
Sbjct: 1283 DSGDMSVRSKSRAPLSSSSSSASSITSPSSNVTTPNSQRSPGLIYRNAKKSNTSNEEFKL 1342
Query: 1422 LLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPSPDAPESP----------------S 1465
LLLKKGSRSD+S RMSA E+LK+ P + E + ++P+S S
Sbjct: 1343 LLLKKGSRSDSSYRMSATEILKS--PILPKPPGELTAESPQSTDDAHQGSQGAEALSPLS 1400
Query: 1466 SCSPSKNRRAQEEWAKNEGLMPRSLSFS-GPRYGRSRTPPSAASSRYSMRNRIQSSPMTV 1524
CSP N EG +S + S R GRSR PP+A+SSRYS+R R+ ++PM
Sbjct: 1401 PCSPRVNA---------EGFSSKSFATSASARVGRSRAPPAASSSRYSVRCRLYNTPMQA 1451
Query: 1525 ISEGEGE 1531
ISEGE E
Sbjct: 1452 ISEGETE 1458
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 120 bits (301), Expect = 1e-26
Identities = 190/754 (25%), Positives = 274/754 (36%), Gaps = 136/754 (18%)
Query: 569 HLATPGYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGNLCNSSDG 628
H A+P SS S Q ++ + S D + S +D+ G+ +S G
Sbjct: 383 HSASPASVRSLGRFSSVSSPQPRSRHPSSS-----SDTWSHSQSSDTIVSDGSTLSSKGG 437
Query: 629 F-GNPRHSVINVFV--------GRAQKNQGDRSNYQD--------KSLSRNISLKKAKKP 671
G P S + V GR + G + D + R++SL+K K+P
Sbjct: 438 SEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRP 497
Query: 672 PLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLP-GKSGSSPSQSPCSDLEE 730
P PP RT SL H L++P G G P ++
Sbjct: 498 PPPPRRTHSL------------------------HQRGLAVPDGPLGLPPKPER---KQQ 530
Query: 731 PWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYT-DPWGYYIDYTGM 789
P LPR + + P + G +P S E T P Y +G
Sbjct: 531 PQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590
Query: 790 QEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPS 849
P G S G P R T + PG SV + S S +PS
Sbjct: 591 PTLPPKGLAGPPASPGKAQPPKP-------ERVTSLRSPGASVSSSLTSLCSSSSDPAPS 643
Query: 850 SGYSSQSNTPTA----LTPVPVFLKSVSPANGKGK-PKPKVPERKSSLISSVSISSSSTS 904
Q TP + P P SP K + P P P + + +S++ S
Sbjct: 644 DRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDAS 703
Query: 905 LSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSP 964
S + + + T + P + +PPP P PS P P + P + P + P
Sbjct: 704 PQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEP 763
Query: 965 LPHSPVFPPPPPEA-------LIPFCSPPDWCLS-----PPRPALSPILPDSP------- 1005
L P +PPPPP A + F P + S P P+ SP L SP
Sbjct: 764 L-QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSA 822
Query: 1006 VSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPP- 1064
+L + PP S +PPPAPP P +S ++ + P + PP
Sbjct: 823 TALQIQPP--GSPDPPPAPP---------APAPASSAPGHVAKLPQKEPVGCSKGGGPPR 871
Query: 1065 ----MPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQE--------QRTPV-APQYHLK 1111
PL+T LQMV+LR V GA L Q+ + +PV AP L
Sbjct: 872 EDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLH 931
Query: 1112 PSAFLKSRN-STNEMESESQPASVTSSLPTPAKSS--------SQGDHGSAAERGGPVSR 1162
+ LK+ + + +E S +QP + P P +S S+G ER PVS
Sbjct: 932 AAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLER--PVSP 989
Query: 1163 SPGAPSAGE--AEARPSPSTTP--LPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAE 1218
A AE R P P SP + PPP+++KP + VPPP P+
Sbjct: 990 ETQADLQRNLVAELRSISEQRPPQAPKKSP-KAPPPVARKPS--VGVPPP-----ASPSY 1041
Query: 1219 NVSEALRAVPSPTTGEEGSVHSREAKESSAAQAG 1252
+E L A P+ G H+++ + A+ G
Sbjct: 1042 PRAEPLTAPPT-----NGLPHTQDRTKRELAENG 1070
Score = 85.5 bits (210), Expect = 4e-16
Identities = 209/907 (23%), Positives = 313/907 (34%), Gaps = 148/907 (16%)
Query: 329 GARANIQSLEPRLGALGPAGDMNGTFLYQRGHPQADENLGHLGGASGTGT--LLRPKSQE 386
GAR ++Q+LE A AG L QR + + +G ++GT L RP S
Sbjct: 270 GARVSLQALE----AEAEAGAETEAML-QRHIDRVYRDDTFVGRSTGTRAPPLTRPMSLA 324
Query: 387 LRHFES----ENIMSPACVVSPHATYSTSIIPNATLSSSSEVIAIPTAQSAGQRESKSSG 442
+ +SPA +SP ATY + +IP+A L + +V+A+
Sbjct: 325 VPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHS 384
Query: 443 SSHARIKSRDHLISRHAVKGDPQSPGRHWNEGHATILSQDLDPHSPGEPALLSLCDSAVP 502
+S A ++S + R + PQ RH + S D HS D+ V
Sbjct: 385 ASPASVRS----LGRFSSVSSPQPRSRHPSS------SSDTWSHSQSS-------DTIVS 427
Query: 503 LNAPANRENGSQAMPYNCRNNLAFPAHPQDVDGKSESSYSGGGGHSSSEPWEYKSSG--N 560
+ + + GS+ P + + + PQ G S SGG +S+ +SSG +
Sbjct: 428 DGSTLSSKGGSEGQPESSTASNSVVPPPQ--GGSGRGSPSGGSTAEASDTLSIRSSGQLS 485
Query: 561 GRASPLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSG-HGS 619
GR+ L+ P T ++ L T G G+
Sbjct: 486 GRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGA 545
Query: 620 G------NLCN------SSDGFGNPRHSVINVFVGRAQKNQGDRSNYQDKSLSRNISLKK 667
G N N S G P S ++ S Y +S + + K
Sbjct: 546 GAAPCPPNPANSWVPGLSPGGSRRPPRS--------PERTLSPSSGYSSQSGTPTLPPKG 597
Query: 668 AKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQSPCSD 727
PP P + P K + L PG S SS S CS
Sbjct: 598 LAGPPASPGKAQ-----PPKPERVT----------------SLRSPGASVSSSLTSLCSS 636
Query: 728 LEEPWLPRSRS--QSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYID 785
+P P RS Q G P V + PS K +P +
Sbjct: 637 SSDP-APSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPS-------KPRSPNPAAPALA 688
Query: 786 YTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHR- 844
+ PG + ++ PT + +QE + Q P S P P +
Sbjct: 689 APAVV--PGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKK 746
Query: 845 ----VISPSSGYSSQS-----NTPTALTPVP----VFLKSVSPAN----GKGKPKPKVPE 887
V +PS+ +++ N P P P + + P P+P P
Sbjct: 747 PEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPS 806
Query: 888 RKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRS 947
L+SS + SSS S T ++ P GSP PP PP P+P P +
Sbjct: 807 GSPELVSSPAASSS------------SATALQIQPP-GSPDPPPAPPAPAPASSAPGHVA 853
Query: 948 PFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVS 1007
LP PV CS+G P V P +L+ + P A +P L S
Sbjct: 854 K-LPQKEPV-GCSKGGGPPREDVGAPLVTPSLLQMVRLRS--VGAPGGAPTPALGPSAPQ 909
Query: 1008 LPLPPPLLPSSEPPPAP------PLDPKFMKDTRPPFTNSGQPES-SRGSLRPPSTKEET 1060
PL L + P PAP + K +S QP RPP + T
Sbjct: 910 KPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPAST 969
Query: 1061 SRPPMPLITTEALQMVQL-RPVRKNSGAEAAQ---LSERTAQEQRTPVAPQ--------Y 1108
+ I ++ + +QL RPV + A+ + R+ EQR P AP+
Sbjct: 970 A----SFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPV 1025
Query: 1109 HLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQ--GDHGSAAERGGPVSRS--P 1164
KPS + S + +E A T+ LP + + ++G + GP + P
Sbjct: 1026 ARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEEKMGLP 1085
Query: 1165 GAPSAGE 1171
G+ S E
Sbjct: 1086 GSDSQKE 1092
Score = 72.0 bits (175), Expect = 4e-12
Identities = 117/504 (23%), Positives = 185/504 (36%), Gaps = 93/504 (18%)
Query: 836 IMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPK------VPERK 889
+ SP+ R PSS + S++ ++ T V S +G+P+ VP +
Sbjct: 399 VSSPQPRSR--HPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQ 456
Query: 890 SSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPP------------VPS 937
S+ S + S SG + ++ PPPPP VP
Sbjct: 457 GGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPD 516
Query: 938 PPF---PCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPR 994
P P P + P PP T S+G+ + PP P + +P SP PPR
Sbjct: 517 GPLGLPPKPERKQQPQLPRPPTTGGSEGAG---AAPCPPNPANSWVPGLSPGG-SRRPPR 572
Query: 995 PALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPP 1054
+ P S S P LP PK + P +S G +PP
Sbjct: 573 SPERTLSPSSGYSSQSGTPTLP-----------PKGLAG----------PPASPGKAQPP 611
Query: 1055 STKEETS-RPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPS 1113
+ TS R P +++ + +S ++ A S+R+ + TP+ ++ + P
Sbjct: 612 KPERVTSLRSPGASVSSSLTSLC-------SSSSDPAP-SDRSGPQILTPLGDRFVIPPH 663
Query: 1114 AFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAE 1173
+ + S S+P S + P A + A GPVS + +P +
Sbjct: 664 PKVPAPFSP----PPSKPRSPNPAAPALA---------APAVVPGPVSTTDASP-----Q 705
Query: 1174 ARPSPSTT---------------PLPDSSPS-RKPPPISKKPKLFLVVPPPQKDFAVEPA 1217
+ P+P TT P P PS PPP +KKP++ +V P + A EP
Sbjct: 706 SPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEV-VVEAPSASETAEEPL 764
Query: 1218 ENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHP-GTSVLEGGAAGSMSPSRV 1276
++ + P+P + +E+ + A P G+ L A S S +
Sbjct: 765 QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATA 824
Query: 1277 EANVPMVQPDVSPAPKQEEPAENS 1300
P PD PAP PA ++
Sbjct: 825 LQIQPPGSPDPPPAPPAPAPASSA 848
Score = 43.9 bits (102), Expect = 0.001
Identities = 242/1122 (21%), Positives = 374/1122 (33%), Gaps = 238/1122 (21%)
Query: 41 QENVFLPTTRPPCVEDLHRQAKLNLKSVL-RECDKLRHDGYRSSQYYSQGPTFAANASPF 99
Q+NVF P+ RPP +E+LH QA+ L+S+ +E KL G + G T + +S
Sbjct: 105 QDNVFFPSGRPPHLEELHTQAQEGLRSLQHQEKQKLNKGG------WDHGDTQSIQSS-- 156
Query: 100 CDDYQDEDEETDQKCSLSSSEEERFISIRRPKTPASSDFSDLNTQTNWTKSLPLPTPEEK 159
DE+ CS ++S E
Sbjct: 157 ---RTGPDEDNISFCSQTTSY----------------------------------VAESS 179
Query: 160 MRQQAQTVQADVVPINITGENFDRQASLRRSLIYTDTLVRRPKKVKRRKTITGVPDNIQK 219
+ A ++++++ I G F S +S RR + +RR T+ G+P ++QK
Sbjct: 180 TAEDALSIRSEM--IQRKGSTFRPHDSFPKS----GKSGRRRR--ERRSTVLGLPQHVQK 231
Query: 220 EL-------ASGT----GQDDA------DGHSVYTPDHYS--TLGRFNSCRSAGQRSET- 259
EL A GT G DA DG T + +L + AG +E
Sbjct: 232 ELGLRNEREAPGTPRAPGARDAVRIPTVDGRPRGTSGMGARVSLQALEAEAEAGAETEAM 291
Query: 260 ---------RDSSCQTEDVKVVPPSMRRIRAQKGQGIAAQMGHFSGSSGNMSVLSDSAGI 310
RD + P + R + G+ G S MS+ + +
Sbjct: 292 LQRHIDRVYRDDTFVGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYL 351
Query: 311 -------VFPSRLDSDAGFHSLPRSGARANIQSLEP-RLGALGPAGDMNGTFLYQRGHPQ 362
V P +D A R+ +R ++ S P + +LG ++ R HP
Sbjct: 352 SKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSR-HPS 410
Query: 363 ADENLGHLGGASGT----GTLLRPKSQELRHFESENIMSPACVVSPHATYSTSIIPNATL 418
+ + +S T G+ L K ES +T S S++P
Sbjct: 411 SSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPES-------------STASNSVVPPPQG 457
Query: 419 SSSSEVIAIPTAQSAGQRESKSSGSSHARIKSRDHLISRHAVKGDPQSPGRHWNEGHATI 478
S P+ S + S S ++ R +S +K P P R + +
Sbjct: 458 GSGR---GSPSGGSTAEASDTLSIRSSGQLSGRS--VSLRKLKRPPPPPRRTHSLHQRGL 512
Query: 479 LSQDLDPHSPGEPALLSLCDSAVPLNAPANRENGSQAMPYNCRNNLA---FPAHPQDVDG 535
D P +P P + G+ P N N+ P +
Sbjct: 513 AVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPR 572
Query: 536 KSESSYSGGGGHSSS--------EPWEYKSSGNGRASPLKPH----LATPGYSTPTSNMS 583
E + S G+SS + + G+A P KP L +PG S +S S
Sbjct: 573 SPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTS 632
Query: 584 SCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGNLCNSSDGFGNPRHSVINVFVGR 643
CS S+ + A S S G L D F P H
Sbjct: 633 LCS----SSSDPAPSDRS----------------GPQILTPLGDRFVIPPH--------- 663
Query: 644 AQKNQGDRSNYQDKSLSRNISLKKAKKP---PLPPSRTDSLRRIPKKSSQCNGQVLNESL 700
K S K S N + P P P S TD+ + P ++
Sbjct: 664 -PKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTP---------QTT 713
Query: 701 IATLQHSLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSA----TTPNV 756
+ LQ S +S SP SP P P + + V A S+ +A PN
Sbjct: 714 LTPLQESPVIS----KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNW 769
Query: 757 YSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHV 816
P + D S +++ P + ++ +P P+G S + +
Sbjct: 770 PPPPPPAPEEQDLS--MADFPPPEEAF--FSVASPEPAGPSGSPELVSSPAASSSSATAL 825
Query: 817 Q---EGSRATMPQVPG---GSVKPKIMS--PEKSHRVISPSSGYSSQSNTPTALTP---V 865
Q GS P P S P ++ P+K S G + +TP
Sbjct: 826 QIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQ 885
Query: 866 PVFLKSV-----SPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKL 920
V L+SV +P G P+ P R++ + + + S+ L ++ + ++
Sbjct: 886 MVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKAC-SLAAS 944
Query: 921 DPAVGSPPAPPPPPVPSPPFPCPADRSPFL-----------PPPPPVT--DCSQGSPLPH 967
+ + P PP P PP PA + F+ P P T D +
Sbjct: 945 EGLSSAQPNGPPEAEPRPP-QSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAEL 1003
Query: 968 SPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPS---SEPPPAP 1024
+ PP+A P SP +PP A P S+ +PPP PS +EP AP
Sbjct: 1004 RSISEQRPPQA--PKKSPK----APPPVARKP-------SVGVPPPASPSYPRAEPLTAP 1050
Query: 1025 PLD--PKFMKDTRPPFTNSG------QPESSRGSLRPPSTKE 1058
P + P T+ +G PE G S KE
Sbjct: 1051 PTNGLPHTQDRTKRELAENGGVLQLVGPEEKMGLPGSDSQKE 1092
Score = 39.7 bits (91), Expect = 0.024
Identities = 96/403 (23%), Positives = 142/403 (35%), Gaps = 46/403 (11%)
Query: 1023 APPLDPKFMKDTRPPFTNSG---QPESSRGSLRPPSTKEETSRPPM---PLITTEALQMV 1076
APPL + M P T +P S S+ P +T P P + AL
Sbjct: 314 APPLT-RPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRC 372
Query: 1077 QLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTS 1136
LR + + S A+ S R+ + +PQ P + S +S S+S V+
Sbjct: 373 SLRTLSRCSLHSASPASVRSLGRFSSVSSPQ----PRSRHPSSSSDTWSHSQSSDTIVSD 428
Query: 1137 SLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSP-STTPLPDSSPSRKPPPI 1195
+K S+G S+ V P G PS ST D+ R +
Sbjct: 429 GSTLSSKGGSEGQPESSTASNSVVP----PPQGGSGRGSPSGGSTAEASDTLSIRSSGQL 484
Query: 1196 SKKP----KLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQA 1251
S + KL PPP++ ++ + AVP G G E K+
Sbjct: 485 SGRSVSLRKLKRPPPPPRR------THSLHQRGLAVPD---GPLGLPPKPERKQQPQLPR 535
Query: 1252 GSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCL 1311
P T EG A P+ + VP + P S P + S +G +S
Sbjct: 536 P-----PTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590
Query: 1312 SQ--QDGAAGVPET--NAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKV 1367
G AG P + A E L+ G + + ++ A RS ++
Sbjct: 591 PTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQI 650
Query: 1368 L---GRRDSDDDHSR-----NHSPSPPVTPTGAAPSLASPKQV 1402
L G R H + + PS P +P AAP+LA+P V
Sbjct: 651 LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVV 693
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 101 bits (252), Expect = 5e-21
Identities = 184/794 (23%), Positives = 275/794 (34%), Gaps = 118/794 (14%)
Query: 714 GKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYS--LCGATPSQSDTSS 771
G + SP +P P P+ + G+ T A TP L P + T+
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1152
Query: 772 VKSEYTDPWGYYIDY-----TGMQEDPGNPAGGCSTSS--GVPTGNGPVRHVQEGSRATM 824
+ + G T P +P GG +T S G PT +G AT
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT- 1211
Query: 825 PQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPK 884
P G P P + +PS TP A P P + P KG P P
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSP--KGAPTTPAATPPSPKGGPATPPP--KGAPTPP 1267
Query: 885 V---PERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFP 941
P K L + + + ++ + S +G A P A PP P SP P
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 942 CP--ADRSPFLPPPPP--------VTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLS 991
P A P + PP P T S+G P S P PP A P ++
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP--AMT 1385
Query: 992 PPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSL 1051
PP P P +P SP P P ++P S P AP P T G S+G L
Sbjct: 1386 PPSPKRGPAIP-SPKGDPTSPAVIPLS-PKKAPAT----------PVTREGAATPSKGDL 1433
Query: 1052 RPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLK 1111
PP+ P+ L A + P +S + L T + P AP+
Sbjct: 1434 TPPAVT------PVSLKKAPATSAPKGGPATPSSKGDPT-LPAVTPPSPKEPPAPKQVAT 1486
Query: 1112 PSAFLKSRNSTNEMESESQPASVTSS-LPTPAKSSSQGDH----GSAAERGGPVSRSPGA 1166
S+ K+ + M + + PA + SS PA SS+ D + + P + +P
Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546
Query: 1167 PSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRA 1226
A PSP TP + P SK+ V P A P E +
Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVT 1606
Query: 1227 VPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPD 1286
PSP +EA A S P T +G +P+ P
Sbjct: 1607 SPSP----------KEAPTPPAVTPPSPEKGPATPAPKG------TPT---------SPP 1641
Query: 1287 VSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMT 1346
V+P+ ++ P ++ T G A VP+ + + + LK EV+
Sbjct: 1642 VTPSSLKDSPTSPASVTCKMG----------ATVPQASKGLPAKKGPTALK-----EVLV 1686
Query: 1347 PSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAP-------SLASP 1399
P +T + A + + ++ + SPP+ P +A S +P
Sbjct: 1687 APAPESTPIITAPTRKGPQT-----------KKSSATSPPICPDPSAKNGSKGPLSTVAP 1735
Query: 1400 KQVGSIQRSIRKSSTSSD---NFKALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEP 1456
+ +Q+ K++ D + K L S++ T +A E + P+ + +
Sbjct: 1736 APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL---PKPESASVSA 1792
Query: 1457 SPDAPES-PSSCSP 1469
+P P S P + SP
Sbjct: 1793 APSPPVSLPLAPSP 1806
Score = 90.5 bits (223), Expect = 1e-17
Identities = 218/958 (22%), Positives = 324/958 (33%), Gaps = 146/958 (15%)
Query: 669 KKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQSPCSDL 728
K P+ +L +P S C ++ A L + KS SPS P
Sbjct: 686 KNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTP 745
Query: 729 EEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTG 788
S ++ A + + P S AT S T + ++ P G + +
Sbjct: 746 PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLG--VSVSP 803
Query: 789 MQEDPGNPAGGCSTSSGVPTGNGPVRHVQ-----------EGSR-------ATMPQVPGG 830
+ P G + + + PV V+ +GS+ + P P G
Sbjct: 804 QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG 863
Query: 831 SVKPKIMSPEKSHRVISPSSGYSSQS--NTPTA----LTPVP-----VFLKSVSPANGKG 879
+ P ++P V P + S N P TP P + + S SP +
Sbjct: 864 APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARA 923
Query: 880 KPKPK----VPERKSSLISSVSISSSSTSLSSSTSTEGSGT-------MKKLDPAVGSPP 928
P PK P K + + S ++ S + + T K PA SP
Sbjct: 924 TPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK 983
Query: 929 APPPPPVPSPPFP--CPADRSP-FLPPPPPVTDCS-QGSP--------LPHSPVFPPPPP 976
P PP +PP P PA SP P PP VT S +GSP P PP P
Sbjct: 984 GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043
Query: 977 EAL-----IPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSE------------ 1019
+ +P +P + P P P P S P PP P S
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATP-SLKGAPTPPAATPPSPKGGPATPSPKGA 1102
Query: 1020 --PPPAPPLDPKFMKDTRP----PFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEAL 1073
PP A P PK T P P T + P S +G L P K P P T +
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK---GAPTTPAATPPSP 1159
Query: 1074 QMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPAS 1133
+ P K + A TP P+A S + + S +
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS--PKGGLATPSPKGA 1217
Query: 1134 VTSSLPTPAKSSSQGDHGSAAERGGPV--SRSPGAPSAGEAEARPSPSTTPLPDSSPSRK 1191
T+ TP S +G + + +G P + +P +P G A P + TP + PS K
Sbjct: 1218 PTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275
Query: 1192 ----PPPISKKPKLFLVVPP-PQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKES 1246
PP P +V PP P+ A P + A P G G+ + A
Sbjct: 1276 GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP 1335
Query: 1247 SAAQAGS---HATHPGTSVLEGGAAGSMSPSRVEANVPMVQ-------PDVSPAPKQEEP 1296
A S T P T+ G G +PS E P P ++P + P
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKG--GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP 1393
Query: 1297 AENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTT--- 1353
A S + + A G+++ + L V P T+
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453
Query: 1354 -----------EDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPV---TPTGAAPSLASP 1399
L A S ++ + S +P+ P PT A +SP
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513
Query: 1400 KQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEML---KNTDPRFQRSRSEP 1456
K+V + S R + A LL K T A ++ E L T P +++ + P
Sbjct: 1514 KEVPATPSSRRDPIAPT----ATLLSK----KTPATLAPKEALIPPAMTVPSPKKTPAIP 1565
Query: 1457 SP-DAPESPSS--------CSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRSRTPPS 1505
+P +AP +PSS +PS + A + E L+P +++ P+ + TPP+
Sbjct: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAP---SPKELLIPPAVTSPSPK--EAPTPPA 1618
Score = 81.3 bits (199), Expect = 7e-15
Identities = 130/527 (24%), Positives = 190/527 (36%), Gaps = 84/527 (15%)
Query: 711 SLPGKSG--SSPSQSPCSDLEEPWLPRSRS-QSTVSAGSSMTSATTPNVYSLCGATPSQS 767
++P G +SP+ P S + P P +R +T S G A TP AT +
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453
Query: 768 DTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTS-SGVPTGNGPVRHVQEGSRATMPQ 826
+ S DP + +E P S+S P P+ T+P
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM------GAPTLPA 1507
Query: 827 VPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPK--PK 884
V S K +P I+P++ S+ TP L P + PA PK P
Sbjct: 1508 VIPSSPKEVPATPSSRRDPIAPTATLLSKK-TPATLAPKEAL---IPPAMTVPSPKKTPA 1563
Query: 885 VPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKL--DPAVGSPPAP--PPPPVPSPPF 940
+P K + + S +SS + ++ +G+ + K+L PAV SP P PP +PP
Sbjct: 1564 IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS 1623
Query: 941 PCPADRSPFLPPP------PPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPP-------- 986
P ++ P P P PPVT S P SP A +P S
Sbjct: 1624 P---EKGPATPAPKGTPTSPPVTPSSLKDS-PTSPASVTCKMGATVPQASKGLPAKKGPT 1679
Query: 987 --DWCLSPPRPALSPIL-------PDSPVSLPLPPPLLPS-----------SEPPPAPPL 1026
L P P +PI+ P + S PP+ P S PAP L
Sbjct: 1680 ALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLL 1739
Query: 1027 DPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSG 1086
+ KD+ S +G L PP +K T +T A + V +P
Sbjct: 1740 PVQ--KDSSKTAKGKDASHSPKGPLAPPESKASTP------LTAAAFEKVLPKP------ 1785
Query: 1087 AEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSS 1146
E+A +S + P+AP S T + + P+S L +P+K +
Sbjct: 1786 -ESASVSAAPSPPVSLPLAP-----------SPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833
Query: 1147 QGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPP 1193
D P S G P P+P + +P +PS K P
Sbjct: 1834 PADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQP 1880
Score = 75.1 bits (183), Expect = 5e-13
Identities = 123/538 (22%), Positives = 192/538 (35%), Gaps = 60/538 (11%)
Query: 713 PGKSGSSPSQSPCSDLEEPWLPRSRSQS-------TVSAGSSMTSATTPNVYSLCGATPS 765
P + + P+ +P S P LP + S + G + +AT + PS
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS 1388
Query: 766 QSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPA---GGCSTSSG---------VPTGNGPV 813
++ S DP + ++ P P G + S G V P
Sbjct: 1389 PKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448
Query: 814 RHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVS 873
+G AT P G P + P +P +S S TP P+ ++
Sbjct: 1449 TSAPKGGPAT-PSSKGDPTLPAVTPPSPKEPP-APKQVATSSSPKKAPATPAPMGAPTL- 1505
Query: 874 PANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPP 933
PA PK +VP SS I+ ++T LS T + + PA+ P P
Sbjct: 1506 PAVIPSSPK-EVPATPSSRRDP--IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP 1562
Query: 934 PVPSPPFPCPADRSPFLPPPPPVTDCS-QGSPLPHSPVFPP----PPPEALIPFCSPPDW 988
+P+P S PP VT + +G+P P + PP P P+ +P
Sbjct: 1563 AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE-----APTPP 1617
Query: 989 CLSPPRPALSPILPDSPVSLPLPPPLLPSS-EPPPAPPLDPKFMKDTRPPFTNSGQPESS 1047
++PP P P P +P P PP+ PSS + P P P + G P
Sbjct: 1618 AVTPPSPEKGPATP-APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLP--- 1673
Query: 1048 RGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQ 1107
+ + P+ +E P P T + P K S A + + + + + P
Sbjct: 1674 --AKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK-GPL 1730
Query: 1108 YHLKPSAFLK-SRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGP------V 1160
+ P+ L ++S+ + + S L P +S +A E+ P V
Sbjct: 1731 STVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV 1790
Query: 1161 SRSPGAPSAGEAEARPSPSTTP----LPDS------SPSRKPPPISKKPKLFLVVPPP 1208
S +P P + P P+ P LP S SPS+ P + L L+ P P
Sbjct: 1791 SAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848
Score = 61.6 bits (148), Expect = 6e-09
Identities = 149/693 (21%), Positives = 228/693 (32%), Gaps = 87/693 (12%)
Query: 502 PLNAPANRENGSQAMPYNCRNNLAFPAHPQDVDGKSESSYSGGGGHSSSEPWEYKSSGNG 561
P P + + G P+ N A P G + S G ++ P K S
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG- 1325
Query: 562 RASPLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGN 621
+P TP TP S + +L T+ G +G T S G
Sbjct: 1326 --TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA 1383
Query: 622 LCNSSDGFG----NPRHSVINVFV----------------GRAQKNQGDRSNYQDKSLSR 661
+ S G +P+ + V G A ++GD +
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT----PPAVT 1439
Query: 662 NISLKKAKK-------PPLPPSRTD-SLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLP 713
+SLKKA P P S+ D +L + S + + ++ + + P
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 714 GKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVK 773
+ + P+ P S E P P SR + ++ T + P S K
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPK 1559
Query: 774 SEYTDPWGYYIDYTGMQEDPGNP-AGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSV 832
P T ++ +P A ST G P+ + + T P
Sbjct: 1560 KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP----KELLIPPAVTSPSPKEAPT 1615
Query: 833 KPKIM--SPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVS-------PANGKGKPKP 883
P + SPEK +P +S TP++L P SV+ P KG P
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675
Query: 884 KVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSP---PF 940
K P ++ V+ + ST + ++ + +G T K + SPP P P + P
Sbjct: 1676 KGPTALKEVL--VAPAPESTPIITAPTRKGPQTKKS---SATSPPICPDPSAKNGSKGPL 1730
Query: 941 PCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALI---------------PFCSP 985
A +P LP + ++G HSP P PPE+ P +
Sbjct: 1731 STVAP-APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESAS 1789
Query: 986 PDWCLSPP-----RPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTN 1040
SPP P+ P LP LP P L+ S P P D + PP
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPI 1849
Query: 1041 SGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEA---AQLSERTA 1097
SG + P+ K +P+ T A Q V K SG E+ + E
Sbjct: 1850 SGGVPFQSVLVNMPTPKS----AGIPVPTPSAKQPVTKN--NKGSGTESDSDESVPELEE 1903
Query: 1098 QEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQ 1130
Q+ Q L +A + + +S S+
Sbjct: 1904 QDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSE 1936
Score = 50.4 bits (119), Expect = 1e-05
Identities = 146/696 (20%), Positives = 231/696 (33%), Gaps = 112/696 (16%)
Query: 717 GSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATT------PNVYSLCGATPSQSDTS 770
G + P ++ E LP+ ++++ V SS S T P + C P Q S
Sbjct: 3 GEATETVPATEQE---LPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLS 59
Query: 771 SVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGG 830
+ P I T ++ P S+ + +P G P + +P + G
Sbjct: 60 AANQASPFPSPSTIASTPLEV----PFPQSSSGTALPLGTAPE------APTFLPNLIGP 109
Query: 831 SVKPKIMSPEKSHRVISPSSGYSSQSNTP---TALTPVPVFLKSVSPANGKGKPKPKVPE 887
+ P ++ + +I+P+ + S+ P AL P V S P N P P V
Sbjct: 110 PISPAALA--LASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP-PSVAV 166
Query: 888 RKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPP--VPSPPFPCPAD 945
+S + ++S + + ++ + K V +P P PP V + P+ C
Sbjct: 167 AESGSVITLSAPIAPSEPKTNLN-------KVPSEVVPNPKGTPSPPCIVSTVPYHCVTP 219
Query: 946 RSPF------LPPPPPVTDCSQGSP------LPHSPVFPPPPPEALIPFCSPPDWCLSPP 993
+ LP P T + SP + + P P + P LS
Sbjct: 220 MASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLS 279
Query: 994 RPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLD--------------PKFMKDTRPPFT 1039
+L + + P PP P S PL P + D P
Sbjct: 280 TQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSD--PTVK 337
Query: 1040 NSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEA-AQLSERTAQ 1098
SS G+ P + + PP+P V PV S + + +S T
Sbjct: 338 TISVDHSSTGASYP---SQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCS 394
Query: 1099 EQRT-PVAPQYHLKPSAFLKSRNSTNEMES----ESQPASVTSSLP-----------TPA 1142
+ VA + L P+ L ++S N P S + P P
Sbjct: 395 PSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPT 454
Query: 1143 KSSSQGDHGSAAERGGPVSR----SPGA----PSAGEAEARPSPSTTPLPDSSPSRKPPP 1194
+ S GP+S SP A P A + + +T +P S P P
Sbjct: 455 TTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPED 514
Query: 1195 ISKKPKLFLVVPPPQKDFAVEPAE-------------------NVSEALRAVPSPTTGEE 1235
+ P LV P QKD PA V ++A P + +
Sbjct: 515 LKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQ 574
Query: 1236 GSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSM-SPSRVEANVPMVQPDVSPAPKQE 1294
+ S E S A + G + G A SM SP V ++ +++ D P
Sbjct: 575 STSSSPEIPLSPEATLAKKSL--GEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSA 632
Query: 1295 EPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSS 1330
P S+ + + AGV T A G+S+
Sbjct: 633 GPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTST 668
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 95.5 bits (236), Expect = 4e-19
Identities = 137/516 (26%), Positives = 204/516 (39%), Gaps = 81/516 (15%)
Query: 854 SQSNTPTA-----LTPVPVFLKSVSPAN-GKGKPKPKVPE--RKSSLISSVSISSSSTSL 905
S+S T T + P+ FL + N G P P VP+ + + S+ + + L
Sbjct: 62 SESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRL 121
Query: 906 SSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPC--PADRSPFLPPPPPVTDCSQGS 963
SS G + D + P PPP P P PP P SP P PP T +
Sbjct: 122 YSSVGDLRPGQYGQ-DLLI---PPPPPGPAPGPPQDISEPPGGSPL--PSPPST-----A 170
Query: 964 PLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLL-----PSS 1018
P P + PPPP ++ P P LSPP SP +P P +P PPL P
Sbjct: 171 PPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPP 230
Query: 1019 EPPPAPPLDPK-FMKDTR--PP----------FTNSGQPESSRGS-LRPPSTKEETSRPP 1064
P PAPP TR PP N Q E++R S R P+ + ++ P
Sbjct: 231 VPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP 290
Query: 1065 MP---LITTEALQMVQLRPVRKNS----GAEAAQLSERTAQEQ---RTPVAPQYHLKPSA 1114
P L + ++ PVR +S A+ A E A ++ R P+ P +H++P++
Sbjct: 291 NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
Query: 1115 FLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEA 1174
+ + E + + + + P +S SQ D ER G +P P
Sbjct: 351 QVYP-DRAPEPDCPGELKATAPASPRLGQSQSQAD-----ERAGTPPPAPPLPPPAPPLP 404
Query: 1175 RPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGE 1234
P+P PLP ++P P P ++K P F P ++ S AL+ P+P
Sbjct: 405 PPAP---PLPPAAP---PLPCAQK------AAHPPAGFTKTP-KSSSPALKPKPNP---- 447
Query: 1235 EGSVHSREAKESSAAQAGSHATHPG-TSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQ 1293
+ E++A+ A P L A + SR E +P + AP+
Sbjct: 448 -------PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500
Query: 1294 EEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSS 1329
+E + + L +D GVPE + GSS
Sbjct: 501 KEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSS 536
Score = 68.6 bits (166), Expect = 5e-11
Identities = 122/463 (26%), Positives = 155/463 (33%), Gaps = 112/463 (24%)
Query: 811 GPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLK 870
G +R Q G +P P G P P+ IS G S + P+ P P L
Sbjct: 126 GDLRPGQYGQDLLIPPPPPG---PAPGPPQD----ISEPPGGSPLPSPPSTAPPPPPLLL 178
Query: 871 SVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPP-- 928
P P P V E ++S T S S T D +PP
Sbjct: 179 EPPPPPSMAPPPPPVLE---------ALSPPHTLSSPSIPTPP-------DFIPPAPPLA 222
Query: 929 --APPPPPVPSPPFPCPADRSPF-----LPPPPPVT-------------DCSQGSPLPHS 968
APPPPPVP+P P PA SP L PP VT + ++ SP P S
Sbjct: 223 FLAPPPPPVPAPAPPAPA--SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASP-PRS 279
Query: 969 PVFPP-----PPPEALIPFCSPPDWCLSPPRPALSPILP----------------DSPVS 1007
P P P PE + F P + + PP P + +P +P
Sbjct: 280 PAEPKGSALGPNPEPHLTF--PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337
Query: 1008 LPLPPP--LLPSSE--PPPAPPLD-PKFMKDTRPPFTNSGQPESSRGS------------ 1050
LPLPP + P+S+ P AP D P +K T P GQ +S
Sbjct: 338 LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLP 397
Query: 1051 -----LRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVA 1105
L PP+ + PP+P A K+S + E A
Sbjct: 398 PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSA 457
Query: 1106 PQYHLKPSAFLKSRNSTNEMESESQPASVTSSL---PTPAKSSSQGDHGSAAER------ 1156
P PS K RN S+ S PT A S +G G
Sbjct: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLS 517
Query: 1157 -------GGPVSRSPGAPSAGEAEARPS---PSTTPLPDSSPS 1189
G +S G S E EA PS PS +P SP+
Sbjct: 518 LPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPT 560
Score = 67.0 bits (162), Expect = 1e-10
Identities = 215/960 (22%), Positives = 307/960 (31%), Gaps = 260/960 (27%)
Query: 818 EGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANG 877
E +RA+ P+ P K + P + P S + TP + +PV +P
Sbjct: 270 EATRASPPRSPA-EPKGSALGPNPEPHLTFPRS-FKVPPPTPVRTSSIPVQEAQEAPRKE 327
Query: 878 KGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPA-------------- 923
+G K K P R S +S + + G +K PA
Sbjct: 328 EGATK-KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADER 386
Query: 924 VGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGS----------PLPHSPVFPP 973
G+PP PP P P+PP P PA P LPP P C+Q + P SP P
Sbjct: 387 AGTPPPAPPLPPPAPPLPPPA---PPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKP 443
Query: 974 ---PPPEALIPFCSPPDW-----------------CLSP---------PRPALSPI---- 1000
PP +P DW C S P P ++P
Sbjct: 444 KPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEG 503
Query: 1001 -----LPDSPVSLPLP----PPLLPS--------SEPPPAPPLDPKFM----KDTRPP-- 1037
LP+ L LP PP +P +E AP L + +D+ P
Sbjct: 504 KKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSV 563
Query: 1038 ----------FTNSGQPES--SRGSLRPPSTKEETSR-------------------PPMP 1066
+++ + E+ S GSL PP + E R PP
Sbjct: 564 RQIRNELEARLSSAAEKEAKPSIGSL-PPKPRLEGGRICENGADDDKLSKPVAKNLPPQS 622
Query: 1067 --LITTEALQ-MVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNS-T 1122
L+ T +LQ L P + + TP P+ L P+ LK+ + T
Sbjct: 623 TTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATP--PKATLGPATPLKATSGPT 680
Query: 1123 NEMESESQPASVTSSLPTPAKSS---SQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPS 1179
+++ S PA +++ P +S ++ D G A + P S+ PS E PS +
Sbjct: 681 TPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEA 740
Query: 1180 TTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVH 1239
T R P ++ F PP+ SP GE ++
Sbjct: 741 T---------RLPTQGARSSAAF----PPK------------------TSPGGGEVPCLY 769
Query: 1240 SREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQ------ 1293
+SS ++ + ++ GGAAG P VE P P PA Q
Sbjct: 770 KPHCHQSSLSREVAVVM---PTLARGGAAGPGEP--VEVKEPPGLPAKPPASAQPTDELL 824
Query: 1294 EEPAENSADTGGDGESCL------SQQDGAAGV------------PETNAAGSSSEACDF 1335
P G + L +Q+ + G ++ A +SS++
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFH 884
Query: 1336 LKEDGNDEVMTPSRPRTTE---DLFAAIHRSKRKVLGRRDSDDDHSRNHS-----PSPPV 1387
+ N + P P+ E L I LGR + SR H+ P PV
Sbjct: 885 SQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPV 944
Query: 1388 TPTGAAPSLAS-----PKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEML 1442
APS PK S K + F ++
Sbjct: 945 AWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP----------------- 987
Query: 1443 KNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGL-MPRSLSFS----GPRY 1497
P F P+P SP +N + N G P +L FS G RY
Sbjct: 988 --PPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARY 1045
Query: 1498 ------------GRS--------RTPPSAASSRYSMRNRIQSSPMTVISEGEGEAVEPVD 1537
GRS P + R SSP + G + V+
Sbjct: 1046 AGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVN 1105
Query: 1538 SIARGALGA--AEGCSLDGLAREEMDEGGLLCGEGPAASLQPQAPGPVD-GTASAEGREP 1594
S R G A SL+G AR AA + +APG D G A A GR P
Sbjct: 1106 SAGRAPPGGLHAPRLSLEGAAR-------------GAAEAKHKAPGSADYGFAPAAGRSP 1152
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 95.5 bits (236), Expect = 4e-19
Identities = 137/516 (26%), Positives = 204/516 (39%), Gaps = 81/516 (15%)
Query: 854 SQSNTPTA-----LTPVPVFLKSVSPAN-GKGKPKPKVPE--RKSSLISSVSISSSSTSL 905
S+S T T + P+ FL + N G P P VP+ + + S+ + + L
Sbjct: 62 SESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRL 121
Query: 906 SSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPC--PADRSPFLPPPPPVTDCSQGS 963
SS G + D + P PPP P P PP P SP P PP T +
Sbjct: 122 YSSVGDLRPGQYGQ-DLLI---PPPPPGPAPGPPQDISEPPGGSPL--PSPPST-----A 170
Query: 964 PLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLL-----PSS 1018
P P + PPPP ++ P P LSPP SP +P P +P PPL P
Sbjct: 171 PPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPP 230
Query: 1019 EPPPAPPLDPK-FMKDTR--PP----------FTNSGQPESSRGS-LRPPSTKEETSRPP 1064
P PAPP TR PP N Q E++R S R P+ + ++ P
Sbjct: 231 VPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP 290
Query: 1065 MP---LITTEALQMVQLRPVRKNS----GAEAAQLSERTAQEQ---RTPVAPQYHLKPSA 1114
P L + ++ PVR +S A+ A E A ++ R P+ P +H++P++
Sbjct: 291 NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
Query: 1115 FLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEA 1174
+ + E + + + + P +S SQ D ER G +P P
Sbjct: 351 QVYP-DRAPEPDCPGELKATAPASPRLGQSQSQAD-----ERAGTPPPAPPLPPPAPPLP 404
Query: 1175 RPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGE 1234
P+P PLP ++P P P ++K P F P ++ S AL+ P+P
Sbjct: 405 PPAP---PLPPAAP---PLPCAQK------AAHPPAGFTKTP-KSSSPALKPKPNP---- 447
Query: 1235 EGSVHSREAKESSAAQAGSHATHPG-TSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQ 1293
+ E++A+ A P L A + SR E +P + AP+
Sbjct: 448 -------PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500
Query: 1294 EEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSS 1329
+E + + L +D GVPE + GSS
Sbjct: 501 KEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSS 536
Score = 68.6 bits (166), Expect = 5e-11
Identities = 122/463 (26%), Positives = 155/463 (33%), Gaps = 112/463 (24%)
Query: 811 GPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLK 870
G +R Q G +P P G P P+ IS G S + P+ P P L
Sbjct: 126 GDLRPGQYGQDLLIPPPPPG---PAPGPPQD----ISEPPGGSPLPSPPSTAPPPPPLLL 178
Query: 871 SVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPP-- 928
P P P V E ++S T S S T D +PP
Sbjct: 179 EPPPPPSMAPPPPPVLE---------ALSPPHTLSSPSIPTPP-------DFIPPAPPLA 222
Query: 929 --APPPPPVPSPPFPCPADRSPF-----LPPPPPVT-------------DCSQGSPLPHS 968
APPPPPVP+P P PA SP L PP VT + ++ SP P S
Sbjct: 223 FLAPPPPPVPAPAPPAPA--SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASP-PRS 279
Query: 969 PVFPP-----PPPEALIPFCSPPDWCLSPPRPALSPILP----------------DSPVS 1007
P P P PE + F P + + PP P + +P +P
Sbjct: 280 PAEPKGSALGPNPEPHLTF--PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337
Query: 1008 LPLPPP--LLPSSE--PPPAPPLD-PKFMKDTRPPFTNSGQPESSRGS------------ 1050
LPLPP + P+S+ P AP D P +K T P GQ +S
Sbjct: 338 LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLP 397
Query: 1051 -----LRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVA 1105
L PP+ + PP+P A K+S + E A
Sbjct: 398 PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSA 457
Query: 1106 PQYHLKPSAFLKSRNSTNEMESESQPASVTSSL---PTPAKSSSQGDHGSAAER------ 1156
P PS K RN S+ S PT A S +G G
Sbjct: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLS 517
Query: 1157 -------GGPVSRSPGAPSAGEAEARPS---PSTTPLPDSSPS 1189
G +S G S E EA PS PS +P SP+
Sbjct: 518 LPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPT 560
Score = 67.0 bits (162), Expect = 1e-10
Identities = 215/960 (22%), Positives = 307/960 (31%), Gaps = 260/960 (27%)
Query: 818 EGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANG 877
E +RA+ P+ P K + P + P S + TP + +PV +P
Sbjct: 270 EATRASPPRSPA-EPKGSALGPNPEPHLTFPRS-FKVPPPTPVRTSSIPVQEAQEAPRKE 327
Query: 878 KGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPA-------------- 923
+G K K P R S +S + + G +K PA
Sbjct: 328 EGATK-KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADER 386
Query: 924 VGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGS----------PLPHSPVFPP 973
G+PP PP P P+PP P PA P LPP P C+Q + P SP P
Sbjct: 387 AGTPPPAPPLPPPAPPLPPPA---PPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKP 443
Query: 974 ---PPPEALIPFCSPPDW-----------------CLSP---------PRPALSPI---- 1000
PP +P DW C S P P ++P
Sbjct: 444 KPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEG 503
Query: 1001 -----LPDSPVSLPLP----PPLLPS--------SEPPPAPPLDPKFM----KDTRPP-- 1037
LP+ L LP PP +P +E AP L + +D+ P
Sbjct: 504 KKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSV 563
Query: 1038 ----------FTNSGQPES--SRGSLRPPSTKEETSR-------------------PPMP 1066
+++ + E+ S GSL PP + E R PP
Sbjct: 564 RQIRNELEARLSSAAEKEAKPSIGSL-PPKPRLEGGRICENGADDDKLSKPVAKNLPPQS 622
Query: 1067 --LITTEALQ-MVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNS-T 1122
L+ T +LQ L P + + TP P+ L P+ LK+ + T
Sbjct: 623 TTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATP--PKATLGPATPLKATSGPT 680
Query: 1123 NEMESESQPASVTSSLPTPAKSS---SQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPS 1179
+++ S PA +++ P +S ++ D G A + P S+ PS E PS +
Sbjct: 681 TPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEA 740
Query: 1180 TTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVH 1239
T R P ++ F PP+ SP GE ++
Sbjct: 741 T---------RLPTQGARSSAAF----PPK------------------TSPGGGEVPCLY 769
Query: 1240 SREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQ------ 1293
+SS ++ + ++ GGAAG P VE P P PA Q
Sbjct: 770 KPHCHQSSLSREVAVVM---PTLARGGAAGPGEP--VEVKEPPGLPAKPPASAQPTDELL 824
Query: 1294 EEPAENSADTGGDGESCL------SQQDGAAGV------------PETNAAGSSSEACDF 1335
P G + L +Q+ + G ++ A +SS++
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFH 884
Query: 1336 LKEDGNDEVMTPSRPRTTE---DLFAAIHRSKRKVLGRRDSDDDHSRNHS-----PSPPV 1387
+ N + P P+ E L I LGR + SR H+ P PV
Sbjct: 885 SQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPV 944
Query: 1388 TPTGAAPSLAS-----PKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEML 1442
APS PK S K + F ++
Sbjct: 945 AWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP----------------- 987
Query: 1443 KNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGL-MPRSLSFS----GPRY 1497
P F P+P SP +N + N G P +L FS G RY
Sbjct: 988 --PPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARY 1045
Query: 1498 ------------GRS--------RTPPSAASSRYSMRNRIQSSPMTVISEGEGEAVEPVD 1537
GRS P + R SSP + G + V+
Sbjct: 1046 AGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVN 1105
Query: 1538 SIARGALGA--AEGCSLDGLAREEMDEGGLLCGEGPAASLQPQAPGPVD-GTASAEGREP 1594
S R G A SL+G AR AA + +APG D G A A GR P
Sbjct: 1106 SAGRAPPGGLHAPRLSLEGAAR-------------GAAEAKHKAPGSADYGFAPAAGRSP 1152
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 95.5 bits (236), Expect = 4e-19
Identities = 137/516 (26%), Positives = 204/516 (39%), Gaps = 81/516 (15%)
Query: 854 SQSNTPTA-----LTPVPVFLKSVSPAN-GKGKPKPKVPE--RKSSLISSVSISSSSTSL 905
S+S T T + P+ FL + N G P P VP+ + + S+ + + L
Sbjct: 62 SESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRL 121
Query: 906 SSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPC--PADRSPFLPPPPPVTDCSQGS 963
SS G + D + P PPP P P PP P SP P PP T +
Sbjct: 122 YSSVGDLRPGQYGQ-DLLI---PPPPPGPAPGPPQDISEPPGGSPL--PSPPST-----A 170
Query: 964 PLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLL-----PSS 1018
P P + PPPP ++ P P LSPP SP +P P +P PPL P
Sbjct: 171 PPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPP 230
Query: 1019 EPPPAPPLDPK-FMKDTR--PP----------FTNSGQPESSRGS-LRPPSTKEETSRPP 1064
P PAPP TR PP N Q E++R S R P+ + ++ P
Sbjct: 231 VPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP 290
Query: 1065 MP---LITTEALQMVQLRPVRKNS----GAEAAQLSERTAQEQ---RTPVAPQYHLKPSA 1114
P L + ++ PVR +S A+ A E A ++ R P+ P +H++P++
Sbjct: 291 NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
Query: 1115 FLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEA 1174
+ + E + + + + P +S SQ D ER G +P P
Sbjct: 351 QVYP-DRAPEPDCPGELKATAPASPRLGQSQSQAD-----ERAGTPPPAPPLPPPAPPLP 404
Query: 1175 RPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGE 1234
P+P PLP ++P P P ++K P F P ++ S AL+ P+P
Sbjct: 405 PPAP---PLPPAAP---PLPCAQK------AAHPPAGFTKTP-KSSSPALKPKPNP---- 447
Query: 1235 EGSVHSREAKESSAAQAGSHATHPG-TSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQ 1293
+ E++A+ A P L A + SR E +P + AP+
Sbjct: 448 -------PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500
Query: 1294 EEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSS 1329
+E + + L +D GVPE + GSS
Sbjct: 501 KEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSS 536
Score = 68.6 bits (166), Expect = 5e-11
Identities = 122/463 (26%), Positives = 155/463 (33%), Gaps = 112/463 (24%)
Query: 811 GPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLK 870
G +R Q G +P P G P P+ IS G S + P+ P P L
Sbjct: 126 GDLRPGQYGQDLLIPPPPPG---PAPGPPQD----ISEPPGGSPLPSPPSTAPPPPPLLL 178
Query: 871 SVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPP-- 928
P P P V E ++S T S S T D +PP
Sbjct: 179 EPPPPPSMAPPPPPVLE---------ALSPPHTLSSPSIPTPP-------DFIPPAPPLA 222
Query: 929 --APPPPPVPSPPFPCPADRSPF-----LPPPPPVT-------------DCSQGSPLPHS 968
APPPPPVP+P P PA SP L PP VT + ++ SP P S
Sbjct: 223 FLAPPPPPVPAPAPPAPA--SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASP-PRS 279
Query: 969 PVFPP-----PPPEALIPFCSPPDWCLSPPRPALSPILP----------------DSPVS 1007
P P P PE + F P + + PP P + +P +P
Sbjct: 280 PAEPKGSALGPNPEPHLTF--PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337
Query: 1008 LPLPPP--LLPSSE--PPPAPPLD-PKFMKDTRPPFTNSGQPESSRGS------------ 1050
LPLPP + P+S+ P AP D P +K T P GQ +S
Sbjct: 338 LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLP 397
Query: 1051 -----LRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVA 1105
L PP+ + PP+P A K+S + E A
Sbjct: 398 PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSA 457
Query: 1106 PQYHLKPSAFLKSRNSTNEMESESQPASVTSSL---PTPAKSSSQGDHGSAAER------ 1156
P PS K RN S+ S PT A S +G G
Sbjct: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLS 517
Query: 1157 -------GGPVSRSPGAPSAGEAEARPS---PSTTPLPDSSPS 1189
G +S G S E EA PS PS +P SP+
Sbjct: 518 LPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPT 560
Score = 67.0 bits (162), Expect = 1e-10
Identities = 215/960 (22%), Positives = 307/960 (31%), Gaps = 260/960 (27%)
Query: 818 EGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANG 877
E +RA+ P+ P K + P + P S + TP + +PV +P
Sbjct: 270 EATRASPPRSPA-EPKGSALGPNPEPHLTFPRS-FKVPPPTPVRTSSIPVQEAQEAPRKE 327
Query: 878 KGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPA-------------- 923
+G K K P R S +S + + G +K PA
Sbjct: 328 EGATK-KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADER 386
Query: 924 VGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGS----------PLPHSPVFPP 973
G+PP PP P P+PP P PA P LPP P C+Q + P SP P
Sbjct: 387 AGTPPPAPPLPPPAPPLPPPA---PPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKP 443
Query: 974 ---PPPEALIPFCSPPDW-----------------CLSP---------PRPALSPI---- 1000
PP +P DW C S P P ++P
Sbjct: 444 KPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEG 503
Query: 1001 -----LPDSPVSLPLP----PPLLPS--------SEPPPAPPLDPKFM----KDTRPP-- 1037
LP+ L LP PP +P +E AP L + +D+ P
Sbjct: 504 KKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSV 563
Query: 1038 ----------FTNSGQPES--SRGSLRPPSTKEETSR-------------------PPMP 1066
+++ + E+ S GSL PP + E R PP
Sbjct: 564 RQIRNELEARLSSAAEKEAKPSIGSL-PPKPRLEGGRICENGADDDKLSKPVAKNLPPQS 622
Query: 1067 --LITTEALQ-MVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNS-T 1122
L+ T +LQ L P + + TP P+ L P+ LK+ + T
Sbjct: 623 TTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATP--PKATLGPATPLKATSGPT 680
Query: 1123 NEMESESQPASVTSSLPTPAKSS---SQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPS 1179
+++ S PA +++ P +S ++ D G A + P S+ PS E PS +
Sbjct: 681 TPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEA 740
Query: 1180 TTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVH 1239
T R P ++ F PP+ SP GE ++
Sbjct: 741 T---------RLPTQGARSSAAF----PPK------------------TSPGGGEVPCLY 769
Query: 1240 SREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQ------ 1293
+SS ++ + ++ GGAAG P VE P P PA Q
Sbjct: 770 KPHCHQSSLSREVAVVM---PTLARGGAAGPGEP--VEVKEPPGLPAKPPASAQPTDELL 824
Query: 1294 EEPAENSADTGGDGESCL------SQQDGAAGV------------PETNAAGSSSEACDF 1335
P G + L +Q+ + G ++ A +SS++
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFH 884
Query: 1336 LKEDGNDEVMTPSRPRTTE---DLFAAIHRSKRKVLGRRDSDDDHSRNHS-----PSPPV 1387
+ N + P P+ E L I LGR + SR H+ P PV
Sbjct: 885 SQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPV 944
Query: 1388 TPTGAAPSLAS-----PKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEML 1442
APS PK S K + F ++
Sbjct: 945 AWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP----------------- 987
Query: 1443 KNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGL-MPRSLSFS----GPRY 1497
P F P+P SP +N + N G P +L FS G RY
Sbjct: 988 --PPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARY 1045
Query: 1498 ------------GRS--------RTPPSAASSRYSMRNRIQSSPMTVISEGEGEAVEPVD 1537
GRS P + R SSP + G + V+
Sbjct: 1046 AGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVN 1105
Query: 1538 SIARGALGA--AEGCSLDGLAREEMDEGGLLCGEGPAASLQPQAPGPVD-GTASAEGREP 1594
S R G A SL+G AR AA + +APG D G A A GR P
Sbjct: 1106 SAGRAPPGGLHAPRLSLEGAAR-------------GAAEAKHKAPGSADYGFAPAAGRSP 1152
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 93.6 bits (231), Expect = 1e-18
Identities = 133/526 (25%), Positives = 200/526 (38%), Gaps = 63/526 (11%)
Query: 795 NPAGGCSTSSGVPTGNG-PVRHVQEGSRATMPQ--VPGGSVKPKIMSPEKSHRVISPSSG 851
+PA ++ G P P + +G +A P P + P S + +PS
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 310
Query: 852 YSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSS-STSLSSSTS 910
+ QS P L P S S P P P S+ S ++ S +T S +T+
Sbjct: 311 AALQSQAPPTLPATP---HSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367
Query: 911 TEGSGTMKKLDPAVGSPPAPP---PPPVPSPPFPCPADRSPFLPPP-PPVTDCSQGSP-- 964
+ GS T++ + SPP P PPP P P ++P PP PP++ + SP
Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 427
Query: 965 -------LPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPS 1017
L +P PPP P PF SPP SPP + +P SL PP +P
Sbjct: 428 PNALAVHLLQAPFSPPPSPPVQAPF-SPP---ASPPVSPSATPPSQAPPSLAAPPLQVPP 483
Query: 1018 SEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQ 1077
S PP +PP+ P + P + P + + PP + PP+ + +
Sbjct: 484 S-PPASPPMSPSATPPPQAPPPLAAPP--LQLAKPPPQAPPALATPPLQALPSPPASFPG 540
Query: 1078 LRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSS 1137
P ++ + L+ Q AP + PS ++ +++ +P
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP-----PASPTLQAPRRP------ 589
Query: 1138 LPTPAKSSS-QGDHGSAAERGG---PVSRSPGAPSAGEAEARPSPSTTPLP------DSS 1187
PTP +S G + A G P SRSP + +G A S S T P DS
Sbjct: 590 -PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 648
Query: 1188 P----SRKPPPISK----KPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVH 1239
P + PPP ++ P + P P F P + P G +++
Sbjct: 649 PEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG-LCTIY 707
Query: 1240 SREAKESSAAQAGS--HATHPGTS---VLEGGAAGSMSPSRVEANV 1280
E ES+ G+ PGTS G AG+ S S +A +
Sbjct: 708 ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 753
Score = 89.7 bits (221), Expect = 2e-17
Identities = 152/609 (24%), Positives = 220/609 (36%), Gaps = 116/609 (19%)
Query: 702 ATLQHSLQLSLPGKSGSSPSQSPCSDL------EEPWLPRSRSQSTVSAGSSMTSATTPN 755
AT+ S + P +S + S++P S E ++ S VS+ + T P
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 756 VYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRH 815
G S +T + + + T+ G + D P + G P+ R
Sbjct: 128 PLGQKGLRISAEETVA-RGKATEAPKRSALSAGARRDTSGP------TPGTPSPAMARRS 180
Query: 816 VQEGSRATMPQ-VPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSP 874
G+ +P+ P +P P KS +S +S +S+ +P A P
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKS---VSSASEHSTTEPSPAARR---------RP 228
Query: 875 ANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPP 934
+ G G +P +S S+SSS+T LSS + S A G+P AP P
Sbjct: 229 SAGGGLQRP----------ASRSLSSSATPLSSPARSGPS--------ARGTPRAPAHPS 270
Query: 935 VPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPR 994
P P A R P + PP + G PL SP+ P P AL +
Sbjct: 271 QPKPK-GLQALRPPQVTPPRKDAAPALG-PLSSSPLATPSPSAAL--------------Q 314
Query: 995 PALSPILPDSPVSLPLPPPL-LPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRP 1053
P LP +P S L L P PP+P P PP T Q +S GS
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 374
Query: 1054 PSTKEETSRPPM-PLIT--TEALQMVQLRPVRKNSGAEAA-QLSERTAQEQRTPVAPQYH 1109
+T PP+ PL T +A + L P++ A+ LS + P A H
Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434
Query: 1110 LKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSA 1169
L + F S P S P +S + P S++P + +A
Sbjct: 435 LLQAPF-------------SPPPSPPVQAPFSPPASP-----PVSPSATPPSQAPPSLAA 476
Query: 1170 GEAEARPSPSTTP--LPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAV 1227
+ PSP +P P ++P + PP P L L PPPQ P + L+A+
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ-----APPALATPPLQAL 531
Query: 1228 PSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDV 1287
PSP A+ PG + A+ MSP A P P V
Sbjct: 532 PSPP-----------------------ASFPGQAPFSPSASLPMSPL---ATPPPQAPPV 565
Query: 1288 SPAPKQEEP 1296
AP + P
Sbjct: 566 LAAPLLQVP 574
Score = 52.4 bits (124), Expect = 4e-06
Identities = 97/388 (25%), Positives = 135/388 (34%), Gaps = 60/388 (15%)
Query: 943 PADRSP-FLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPI- 1000
PA R+P L P PP GSP P PP P AL + P I
Sbjct: 17 PAARAPGLLTPRPP------GSPRPP----PPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 1001 ---LPDS-PVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPST 1056
+P+S P + P S P PP + + PP N+ S G + P
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGR--GERAPPAKNT-----SPGPVSSPGR 119
Query: 1057 KEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQR-----TPVAPQYHLK 1111
T+RP + + L++ V + EA + S +A +R TP P
Sbjct: 120 ASGTTRPGP--LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS---- 173
Query: 1112 PSAFLKSRNSTNEMESESQPASVTSSLPT--PAKSSSQGDHGSAAERGGPVSRSPGAPSA 1169
P+ +SR + E+ S PT P KS S S E R P A
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233
Query: 1170 GEAEARPSPSTTPLPDSSPSRKPP-----------PISKKPKLFLVVPPPQKDFAVEPAE 1218
+ A S S++ P SSP+R P P KPK + PPQ V P
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ----VTPP- 288
Query: 1219 NVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEA 1278
R +P G S S+A Q+ + T P T +P +
Sbjct: 289 ------RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
Query: 1279 NVPMVQPDVS--PAPKQEEPAENSADTG 1304
P P + P+P P++ + G
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLG 370
Score = 35.8 bits (81), Expect = 0.34
Identities = 63/266 (23%), Positives = 95/266 (35%), Gaps = 42/266 (15%)
Query: 1156 RGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVV---------P 1206
+ G +R+P A + G TP P SP R PPP++ P V+ P
Sbjct: 9 KAGAAARTPAARAPG--------LLTPRPPGSP-RPPPPVT--PAALRVLGAAGAVGRKP 57
Query: 1207 PPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHA-----THPGTS 1261
++ + A A RA P T G+ A A+ G A T PG
Sbjct: 58 LAERAGGIGGATIPESAPRAGP---TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPV 114
Query: 1262 VLEGGAAGSMSPS-------RVEANVPMVQPDVSPAPKQEEPA-----ENSADTGGDGES 1309
G A+G+ P R+ A + + + APK+ + + S T G
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
Query: 1310 CLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLG 1369
++++ AAG + S E V + S TTE AA R + G
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA--RRRPSAGG 232
Query: 1370 RRDSDDDHSRNHSPSPPVTPTGAAPS 1395
S + S +P +P + PS
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPS 258
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 93.2 bits (230), Expect = 2e-18
Identities = 96/406 (23%), Positives = 144/406 (35%), Gaps = 59/406 (14%)
Query: 845 VISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTS 904
+ +PS ++ S PT+ T +P P P P + S I++++T
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPP-------TTTPSPPITTTTTP 1448
Query: 905 LSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVT------D 958
++T + P + + PPP PSPP P+ P P PP T
Sbjct: 1449 PPTTTPS----------PPISTTTTPPPTTTPSPPTTTPS--PPTTTPSPPTTTTTTPPP 1496
Query: 959 CSQGSPLPHSPVFPPPPPEALIPFC--SPPDWCLSPPRPALSPILPDSPVSLPLPPPLLP 1016
+ SP +P+ PP L P SPP + P P + P P + P+ PP
Sbjct: 1497 TTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTT---PSPPTTTPITPPTST 1553
Query: 1017 SSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRP---PMPLITTEAL 1073
++ PP P P T PP T P ++ S PP+ T P P P TT
Sbjct: 1554 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS--PPTITTTTPPPTTTPSPPTTTTTT 1611
Query: 1074 QMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPAS 1133
P + S T TP P +T + P+
Sbjct: 1612 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP------------TTTTTPPPTTTPSP 1659
Query: 1134 VTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTP--------LPD 1185
T++ P+P +++ + P++ +P P+ PSP+TTP P
Sbjct: 1660 PTTTTPSPPITTTTTPPPTTTP-SSPITTTPSPPTT--TMTTPSPTTTPSSPITTTTTPS 1716
Query: 1186 SSPSRKPPPIS-KKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSP 1230
S+ + PPP + P PP P S L P P
Sbjct: 1717 STTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLP 1762
Score = 67.4 bits (163), Expect = 1e-10
Identities = 90/438 (20%), Positives = 142/438 (32%), Gaps = 51/438 (11%)
Query: 752 TTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNG 811
TTP+ + + P S T+ + P P P +T T +
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 812 PVRHVQEGSRATMPQVPGGSVKPKIMSPEK-SHRVISPSSGYSSQSNTPTALTPVPVFLK 870
P+ T P P + P +P + +P + T T +TP P
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-PASTT 1515
Query: 871 SVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAP 930
++ P P + S ++ T +S+T+ + T +PP
Sbjct: 1516 TLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1575
Query: 931 PPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCL 990
P P+ P P + PPP +P P + PPP
Sbjct: 1576 TTPSPPTTTTPSPPTITTTTPPPTT-------TPSPPTTTTTTPPPTT------------ 1616
Query: 991 SPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGS 1050
+P P +PI P + + LPP PS PPP P PP T + P + +
Sbjct: 1617 TPSPPTTTPITPPTSTT-TLPPTTTPS--PPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673
Query: 1051 LRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHL 1110
PP T+ P P+ TT + + + + + T TP P
Sbjct: 1674 TPPP-----TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPP---- 1724
Query: 1111 KPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAG 1170
P+ +T + S P + ++LP SS P++ +P PS
Sbjct: 1725 -PTTMTTPSPTT----TPSPPTTTMTTLPPTTTSS-------------PLTTTPLPPSIT 1766
Query: 1171 EAEARPSPSTTPLPDSSP 1188
P +TTP P
Sbjct: 1767 PPTFSPFSTTTPTTPCVP 1784
Score = 65.9 bits (159), Expect = 3e-10
Identities = 78/365 (21%), Positives = 114/365 (31%), Gaps = 32/365 (8%)
Query: 943 PADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSP---------- 992
P D+ P PP T + P P P PP SP
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450
Query: 993 ---PRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRG 1049
P P +S P + P PP PS PP P P T PP T P ++
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPS--PPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508
Query: 1050 SLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAP--Q 1107
+ +T + P P TT P + S T TP P
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568
Query: 1108 YHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAP 1167
P S +T + P ++T++ P P + S + P + +P P
Sbjct: 1569 TTTPPPTTTPSPPTT----TTPSPPTITTTTPPPTTTPSP---PTTTTTTPPPTTTPSPP 1621
Query: 1168 SAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAV 1227
+ P STT LP ++ PP + P PP P +
Sbjct: 1622 TT--TPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT-----T 1674
Query: 1228 PSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGS-MSPSRVEANVPMVQPD 1286
P PTT + + + ++ S T P + + S +PS + P
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734
Query: 1287 VSPAP 1291
+P+P
Sbjct: 1735 TTPSP 1739
Score = 65.1 bits (157), Expect = 5e-10
Identities = 78/336 (23%), Positives = 122/336 (36%), Gaps = 26/336 (7%)
Query: 734 PRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDP 793
P + +S ++ TTP+ + + P+ + + + T P + P
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP--PTTTPSPPTTTP 1507
Query: 794 GNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYS 853
P +T T + P T P P + P ++P S + P++ S
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP--TTTP--ITPPTSTTTLPPTTTPS 1563
Query: 854 SQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEG 913
T T TP P + SP P + ++ S +++T+ T+T
Sbjct: 1564 PPPTTTT--TPPPT--TTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS 1619
Query: 914 SGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPP 973
T + P S PP PSPP P P PP T + SP + PP
Sbjct: 1620 PPTTTPITPPT-STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTT--TTPSPPITTTTTPP 1676
Query: 974 P---PPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKF 1030
P P + SPP ++ P P +P S P+ PSS P+PP P
Sbjct: 1677 PTTTPSSPITTTPSPPTTTMTTPSPTTTP-------SSPITTTTTPSSTTTPSPP--PTT 1727
Query: 1031 MKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMP 1066
M T P T P ++ +L P +T + P+P
Sbjct: 1728 M-TTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLP 1762
Score = 63.2 bits (152), Expect = 2e-09
Identities = 67/272 (24%), Positives = 93/272 (34%), Gaps = 27/272 (9%)
Query: 983 CSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPS------SEPPPAPPLDPKFMKDTRP 1036
C P D C++ P P + P + LPP PS + PPP P T P
Sbjct: 1389 CWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448
Query: 1037 PFTNSGQPESSRGSLRPPST--KEETSRP------PMPLITTEALQMVQLRPVRKNSGAE 1088
P T + P S + PP+T T+ P P P TT P +
Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508
Query: 1089 AAQLSERTAQEQRTPVAP--QYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKS-- 1144
S T TP P P S +T + + P S T+ PT S
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI---TPPTSTTTLPPTTTPSPP 1565
Query: 1145 -SSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPP-ISKKPKLF 1202
++ P + +P P+ P P+TTP P ++ + PPP + P
Sbjct: 1566 PTTTTTPPPTTTPSPPTTTTPSPPTI--TTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTT 1623
Query: 1203 LVVPPPQKDFAVEPAENVS--EALRAVPSPTT 1232
+ PP + P S P PTT
Sbjct: 1624 TPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1655
Score = 58.5 bits (140), Expect = 5e-08
Identities = 108/495 (21%), Positives = 174/495 (35%), Gaps = 78/495 (15%)
Query: 738 SQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPA 797
+Q+ + + T+ TP TP+ + ++ + P TG Q P
Sbjct: 3963 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPI 4017
Query: 798 GGCSTSSGVPTGNGP----VRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPS---S 850
+T + PT G + + T P G+ P +P + ++P+ +
Sbjct: 4018 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPT 4076
Query: 851 GYSSQSNTP----TALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLS 906
G + + TP T +TP P + +P V + + ++ T+ +
Sbjct: 4077 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4136
Query: 907 SSTSTEG-SGTMKKLDPAVGSPPAPPPPPVPS---PPFPCPADRSPFLPPPPPVTDCSQG 962
+ T T +GT + + P P P+ P P + + P P T G
Sbjct: 4137 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG 4196
Query: 963 SPLPHSPVFP-------PPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLL 1015
P H+ P PPPE+ P S R SP+ + + LPP +
Sbjct: 4197 PPT-HTSTAPIAELTTSNPPPESSTPQTS---------RSTSSPLTESTTLLSTLPPAIE 4246
Query: 1016 PSSEPPPAPP-----------LDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSR-- 1062
+S PP+ P L P T PP T + + S PST + T+
Sbjct: 4247 MTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 4306
Query: 1063 ---PPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLK-S 1118
P PL T ++ LRP S + T V + F+ S
Sbjct: 4307 WTPTPTPLSTPSIIRTTGLRPY--PSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 4364
Query: 1119 RNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSP 1178
+ T E + S P S S PTP+KS+ +P PS+ ++P+P
Sbjct: 4365 LSCTLEFYNWSCP-STPSPTPTPSKSTP----------------TPSKPSS--TPSKPTP 4405
Query: 1179 STTP--LPDSSPSRK 1191
T P PD P R+
Sbjct: 4406 GTKPPECPDFDPPRQ 4420
Score = 52.0 bits (123), Expect = 5e-06
Identities = 95/521 (18%), Positives = 174/521 (33%), Gaps = 50/521 (9%)
Query: 738 SQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPA 797
+Q+ + + T+ TP TP+ + ++ + P TG Q P
Sbjct: 3802 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPI 3856
Query: 798 GGCSTSSGVPTGNGP----VRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPS---S 850
+T + PT G + + T P G+ P +P + ++P+ +
Sbjct: 3857 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPT 3915
Query: 851 GYSSQSNTP----TALTPVPVFLKSVSPANGK------GKPKPKVPERKSSLISSVSISS 900
G + + TP T +TP P + +P P P ++ + ++ ++
Sbjct: 3916 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3975
Query: 901 SSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPV-TDC 959
+ T + T T+ + T + P P P +P + P P P T
Sbjct: 3976 TVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4034
Query: 960 SQGSPLPHSP-VFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSS 1018
+P+ + V P P P + P + P +P +P + P+ +
Sbjct: 4035 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4094
Query: 1019 EPPPAPPLDPKFMKDTRPPFTNSGQ---PESSRGSLRPPSTKEETSRPPMPLITTEALQM 1075
P P P T P T + + G+ P +T T+ P T Q
Sbjct: 4095 TPTPTGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4149
Query: 1076 VQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQP-ASV 1134
P+ + T TP+ + P+ + + + P A +
Sbjct: 4150 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAEL 4209
Query: 1135 TSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSP---SRK 1191
T+S P P S+ Q +++ + P A E + PST P ++ +
Sbjct: 4210 TTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269
Query: 1192 PPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTT 1232
PPP + PP P + + P+P+T
Sbjct: 4270 PPPST-------TTSPPG-----TPTRGTTTGSSSAPTPST 4298
Score = 50.4 bits (119), Expect = 1e-05
Identities = 97/482 (20%), Positives = 159/482 (32%), Gaps = 87/482 (18%)
Query: 738 SQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPA 797
+Q+ + + T+ TP TP+ + ++ + P TG Q P
Sbjct: 3894 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPI 3948
Query: 798 GGCSTSSGVPTGNGP----VRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPS---S 850
+T + PT G + + T P G+ P +P + ++P+ +
Sbjct: 3949 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPT 4007
Query: 851 GYSSQSNTP----TALTPVPVFLKSVSPANGK------GKPKPKVPERKSSLISSVSISS 900
G + + TP T +TP P + +P P P ++ + ++ ++
Sbjct: 4008 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4067
Query: 901 SSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSP------------PFPCPADRSP 948
+ T + T T+ + T + P P P +P P P P
Sbjct: 4068 TVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4126
Query: 949 FLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSL 1008
P T +P P P P +P P +PI + V+
Sbjct: 4127 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT- 4185
Query: 1009 PLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLI 1068
P P P + PP P T P S P++SR S P T+ T +P
Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSR-STSSPLTESTTLLSTLP-- 4242
Query: 1069 TTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESE 1128
A++M P TP AP +T+ +
Sbjct: 4243 --PAIEMTSTAP-------------------PSTPTAP-------------TTTSGGHTL 4268
Query: 1129 SQPASVTSSLP-TPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSS 1187
S P S T+S P TP + ++ G S S PS + + + TP P S+
Sbjct: 4269 SPPPSTTTSPPGTPTRGTTTG------------SSSAPTPSTVQTTTTSAWTPTPTPLST 4316
Query: 1188 PS 1189
PS
Sbjct: 4317 PS 4318
Score = 37.7 bits (86), Expect = 0.090
Identities = 60/331 (18%), Positives = 100/331 (30%), Gaps = 38/331 (11%)
Query: 926 SPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLP---------------HSPV 970
+PP P + P P P P+T + +P P + V
Sbjct: 1894 TPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1953
Query: 971 FPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKF 1030
P P P + P + P +P +P + P+ + P P P
Sbjct: 1954 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-- 2011
Query: 1031 MKDTRPPFTNS---GQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGA 1087
T P T + + G+ P +T T+ P T Q P+ +
Sbjct: 2012 ---TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2068
Query: 1088 EAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSL-PTPAKSSS 1146
T TP+ + P+ T + P + T+++ PTP + +
Sbjct: 2069 TPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGT 2123
Query: 1147 QGDHGSAAERGGPVSRSPGAPSAGEAEARPSPST-----TPLPDSSPSRKPPPISKKPKL 1201
Q + V+ +P P +T TP P + + PI+
Sbjct: 2124 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-- 2181
Query: 1202 FLVVPPPQKDFAVEPAEN-VSEALRAVPSPT 1231
V P P P ++ P+PT
Sbjct: 2182 -TVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2211
Score = 31.6 bits (70), Expect = 6.5
Identities = 18/52 (34%), Positives = 21/52 (40%), Gaps = 8/52 (15%)
Query: 926 SPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPE 977
S P+P P P S P P +P P P G+ P P F PP E
Sbjct: 4378 STPSPTPTPSKSTPTPSKPSSTPSKPTP--------GTKPPECPDFDPPRQE 4421
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 92.4 bits (228), Expect = 3e-18
Identities = 133/530 (25%), Positives = 201/530 (37%), Gaps = 76/530 (14%)
Query: 788 GMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVIS 847
G+Q +T P +GP +R T P+ P +PK K + +
Sbjct: 224 GLQRPASRSLSSSATPLSSPARSGP------SARGT-PRAPAHPSQPK----PKGLQALR 272
Query: 848 PSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSS-STSLS 906
P + + AL P+ S SP P P P S+ S ++ S +T S
Sbjct: 273 PPQVTPPRKDAAPALGPL-----SSSPL---ATPSPSAPPSPSAPPSLQTLPSPPATPPS 324
Query: 907 SSTSTEGSGTMKKLDPAVGSPPAPP---PPPVPSPPFPCPADRSPFLPPP-PPVTDCSQG 962
+T++ GS T++ + SPP P PPP P P ++P PP PP++ +
Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384
Query: 963 SP---------LPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPP 1013
SP L +P PPP P PF SPP SPP + +P SL PP
Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPF-SPP---ASPPVSPSATPPSQAPPSLAAPPL 440
Query: 1014 LLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEAL 1073
+P S PP +PP+ P + P + P + + PP + PP+ + +
Sbjct: 441 QVPPS-PPASPPMSPSATPPPQAPPPLAAPP--LQLAKPPPQAPPALATPPLQALPSPPA 497
Query: 1074 QMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPAS 1133
P ++ + L+ Q AP + PS ++ +++ +P
Sbjct: 498 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP-----PASPTLQAPRRP-- 550
Query: 1134 VTSSLPTPAKSSS-QGDHGSAAERGG---PVSRSPGAPSAGEAEARPSPSTTPLP----- 1184
PTP +S G + A G P SRSP + +G A S S T P
Sbjct: 551 -----PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 605
Query: 1185 -DSSP----SRKPPPISK----KPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEE 1235
DS P + PPP ++ P + P P F P + P G
Sbjct: 606 YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG-L 664
Query: 1236 GSVHSREAKESSAAQAGS--HATHPGTS---VLEGGAAGSMSPSRVEANV 1280
+++ E ES+ G+ PGTS G AG+ S S +A +
Sbjct: 665 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 714
Score = 78.2 bits (191), Expect = 6e-14
Identities = 135/562 (24%), Positives = 196/562 (34%), Gaps = 110/562 (19%)
Query: 751 ATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGN 810
AT P G T + +S + E P PG P +SG T
Sbjct: 68 ATIPESAPRAGPTRTSRPPASGRGERAPP--------AKNTSPG-PVSSPGRASGT-TRP 117
Query: 811 GPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLK 870
GP+ Q+G R + + + +P++S + S+G ++ PT TP P +
Sbjct: 118 GPLG--QKGLRISAEETVARGKATE--APKRS----ALSAGARRDTSGPTPGTPSPAMAR 169
Query: 871 SVSPAN---GKGKPKPKVPERKSSLISSVSISSSSTSLSSSTS-------TEGSGTMKKL 920
A G +P P R + S+SS+S ++ S + G G +
Sbjct: 170 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 229
Query: 921 DPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALI 980
++ S P P S P R+P P P +G P PP +A
Sbjct: 230 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK----PKGLQALRPPQVTPPRKDA-- 283
Query: 981 PFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTN 1040
PAL P L SP++ P P PP+P P PP T
Sbjct: 284 -------------APALGP-LSSSPLATPSP-------SAPPSPSAPPSLQTLPSPPATP 322
Query: 1041 SGQPESSRGSLRPPSTKEETSRPPM-PLIT--TEALQMVQLRPVRKNSGAEAA-QLSERT 1096
Q +S GS +T PP+ PL T +A + L P++ A+ LS
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 382
Query: 1097 AQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAER 1156
+ P A HL + F S P S P +S +
Sbjct: 383 TPSPQAPNALAVHLLQAPF-------------SPPPSPPVQAPFSPPASP-----PVSPS 424
Query: 1157 GGPVSRSPGAPSAGEAEARPSPSTTP--LPDSSPSRKPPPISKKPKLFLVVPPPQKDFAV 1214
P S++P + +A + PSP +P P ++P + PP P L L PPPQ
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ----- 479
Query: 1215 EPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPS 1274
P + L+A+PSP A+ PG + A+ MSP
Sbjct: 480 APPALATPPLQALPSPP-----------------------ASFPGQAPFSPSASLPMSPL 516
Query: 1275 RVEANVPMVQPDVSPAPKQEEP 1296
A P P V AP + P
Sbjct: 517 ---ATPPPQAPPVLAAPLLQVP 535
Score = 52.4 bits (124), Expect = 4e-06
Identities = 96/387 (24%), Positives = 138/387 (35%), Gaps = 64/387 (16%)
Query: 943 PADRSP-FLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPIL 1001
PA R+P L P PP GSP P PPP A + P + +
Sbjct: 17 PAARAPGLLTPRPP------GSPRP-----PPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 1002 PDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQ-----PESSRGSLRPPST 1056
+ + P S P P + +RPP + G+ +S G + P
Sbjct: 66 GGATI---------PESAPRAGPT------RTSRPPASGRGERAPPAKNTSPGPVSSPGR 110
Query: 1057 KEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQR-----TPVAPQYHLK 1111
T+RP + + L++ V + EA + S +A +R TP P
Sbjct: 111 ASGTTRPGP--LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS---- 164
Query: 1112 PSAFLKSRNSTNEMESESQPASVTSSLPT--PAKSSSQGDHGSAAERGGPVSRSPGAPSA 1169
P+ +SR + E+ S PT P KS S S E R P A
Sbjct: 165 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 224
Query: 1170 GEAEARPSPSTTPLPDSSPSRKPP-----------PISKKPKLFLVVPPPQ----KDFAV 1214
+ A S S++ P SSP+R P P KPK + PPQ + A
Sbjct: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284
Query: 1215 EPAENVSEALRAVPSPTTGEEGSV-HSREAKESSAAQAGSHATHP-GTSVLEGGAAGSMS 1272
+S + A PSP+ S S + S A S AT G+ L+ + S
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 1273 P--SRVEANVPMVQPDVSPAPKQEEPA 1297
P S + P P ++ P Q P+
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPS 371
Score = 40.4 bits (93), Expect = 0.014
Identities = 78/332 (23%), Positives = 116/332 (34%), Gaps = 53/332 (15%)
Query: 1156 RGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVV---------P 1206
+ G +R+P A + G TP P SP R PPP++ P V+ P
Sbjct: 9 KAGAAARTPAARAPG--------LLTPRPPGSP-RPPPPVT--PAALRVLGAAGAVGRKP 57
Query: 1207 PPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGG 1266
++ + A A RA P+ T+ S A + T PG G
Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAK-------NTSPGPVSSPGR 110
Query: 1267 AAGSMSPS-------RVEANVPMVQPDVSPAPKQEEPA-----ENSADTGGDGESCLSQQ 1314
A+G+ P R+ A + + + APK+ + + S T G ++++
Sbjct: 111 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 170
Query: 1315 DGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSD 1374
AAG + S E V + S TTE AA R + G
Sbjct: 171 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA--RRRPSAGGGLQRP 228
Query: 1375 DDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSA 1434
S + S +P +P + PS G+ + S +AL T
Sbjct: 229 ASRSLSSSATPLSSPARSGPSAR-----GTPRAPAHPSQPKPKGLQAL----RPPQVTPP 279
Query: 1435 RMSAAEMLKNTDPRFQRSRSEPSPDAPESPSS 1466
R AA L P + PSP AP SPS+
Sbjct: 280 RKDAAPAL---GPLSSSPLATPSPSAPPSPSA 308
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 90.5 bits (223), Expect = 1e-17
Identities = 141/550 (25%), Positives = 193/550 (35%), Gaps = 118/550 (21%)
Query: 712 LPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSM-------TSATTPNVYSLCGA-- 762
LP P P P LP SQS SAGS+ T N GA
Sbjct: 628 LPPPPPPPPPPPPPPPPPPPPLP---SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684
Query: 763 ---TPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEG 819
TP + SVK + P + P P + P
Sbjct: 685 KPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA---------- 734
Query: 820 SRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKG 879
P +P S P P K H+V + +Q PT P P+ +P +
Sbjct: 735 -----PSLPQFSAPPP---PLKIHQV-----QHITQVAPPTPPPPPPI----PAPLPPQA 777
Query: 880 KPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLD--PAVGSPPAPPPPPVPS 937
PKP V + S+ +++ T + T T KK PA PP+PP PPVP
Sbjct: 778 PPKPLVTIPAPT--STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPV 835
Query: 938 PPFPCPADRSPFLPPPPPVTDCSQGSPLPH-----SPVFPPPPPEALIPFCSPPDWCLSP 992
PP P +S PPP S SP+P + FPPPP +PP P
Sbjct: 836 PPPTLPKQQSFCAKPPP-----SPLSPVPSVVKQIASQFPPPP--------TPPAMESQP 882
Query: 993 PRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLR 1052
+P + + P SP ++ P PSS P P+P P PP PESS
Sbjct: 883 LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPP-------PP------PESSLVFPP 929
Query: 1053 PPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQ-EQRTPVAPQYH-- 1109
PP + PP P + P SG+ + S+ ++ ++ P PQ +
Sbjct: 930 PPPSPVPAPPPPPPPTAS---------PTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS 980
Query: 1110 LKPSAFLK----SRNSTNEMESESQPASVTSS-----LPTPAKSSSQGD----------- 1149
+K S+ + R S + + S+ P + + S LP PA G
Sbjct: 981 IKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGV 1040
Query: 1150 -HGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPI--------SKKPK 1200
PV G S E + PS S P P PPI + PK
Sbjct: 1041 LQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPK 1100
Query: 1201 LFLVVPPPQK 1210
+ +V P PQ+
Sbjct: 1101 VAVVNPQPQQ 1110
Score = 87.8 bits (216), Expect = 8e-17
Identities = 143/572 (25%), Positives = 201/572 (35%), Gaps = 86/572 (15%)
Query: 836 IMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKP--KPKVPERKSSLI 893
I S S + S +S+QS++ + T ++S S + K +SS
Sbjct: 534 IKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKA 593
Query: 894 SSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPP 953
S++ TSL S + K + P S P+PP PP P PP P P P PPP
Sbjct: 594 RMESMNRPYTSLVPPLSPQP----KIVTPYTASQPSPPLPPPPPPPPPPP---PPPPPPP 646
Query: 954 PPVTDCSQGSPLPHSPVF---------------------PPPPP----EALIP-FCSPPD 987
PP+ S S +P+F PP PP +++ P PP+
Sbjct: 647 PPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPN 706
Query: 988 WCLSPPRPALSPILPDSPVSLPLPPPLLPS----SEPPP-------------APPLDPKF 1030
+ PP P P P S ++ P P PS S PPP APP P
Sbjct: 707 GVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP-- 764
Query: 1031 MKDTRPPFTNSGQPESSRGSL--RPPSTKEETSRPPMPLITTEALQMVQLRPV--RKNSG 1086
PP P++ L P T +T P + T+A PV K
Sbjct: 765 ---PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP----VVTQAAPPTPTPPVPPAKKQP 817
Query: 1087 AEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSS 1146
A A + PV P K +F + S + S P P +
Sbjct: 818 AFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPA 877
Query: 1147 QGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVP 1206
S + P + +P +P A +A+ + PS+ P+P SP PPP P+ LV P
Sbjct: 878 M---ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP--SPDFPPPP----PESSLVFP 928
Query: 1207 PPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHAT-HPGTSVLEG 1265
PP P SPT + GS + +K SS T +S+
Sbjct: 929 PPPP----SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSS 984
Query: 1266 GAAGSMSPSR--VEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPET 1323
A P R V++ V P +E A G+ LS +P
Sbjct: 985 SGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLS----GVNLPGV 1040
Query: 1324 NAAGSSSEACDFLKEDGNDEVMT-PSRPRTTE 1354
G S L G D V+ PS P ++
Sbjct: 1041 LQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSD 1072
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 90.1 bits (222), Expect = 2e-17
Identities = 120/486 (24%), Positives = 171/486 (35%), Gaps = 105/486 (21%)
Query: 859 PTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMK 918
P A P P L + AN G P+P + E K
Sbjct: 1426 PAAAVPGPPPLPGLPSANSNGTPEPPLLEEKP---------------------------- 1457
Query: 919 KLDPAVGSPPAPPPPPVPSP-PFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPE 977
PP PPP P P P P P P P LP PPP+ + SP P P PPPPP
Sbjct: 1458 --------PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPP--PPLPPPPPP 1507
Query: 978 ALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPP 1037
A+ SPP PP PA +P+ + P P PS E P P P + +
Sbjct: 1508 AM---PSPP----PPPPPAAAPL------AAPPEEPAAPSPEDPELPDTRPLHLAKKQET 1554
Query: 1038 FTNSGQPESSRGS--------------LRP---PSTK--EETSRPPMPLITTEALQMVQL 1078
G+ + G +R PS K +T R P P+ + + +
Sbjct: 1555 AAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKF 1614
Query: 1079 RPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSL 1138
P K+ + S +Y FL++ N + + ++
Sbjct: 1615 TPEIKDGQRQFCATSNYLG--YFGDAKNRYQRLYVKFLENVNKKDYVRVCAR--KPWHRP 1670
Query: 1139 PTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKK 1198
P P + S Q + +A GG + P AP+ P P T P+ + S KPP +
Sbjct: 1671 PVPVRRSGQAKNPVSA--GGSSAPPPKAPA-----PPPKPET---PEKTTSEKPP--EQT 1718
Query: 1199 PKLFLVVPP-PQKDFAVEPAENVSEALRAV--PSPTTGEEGSVHSREAKESSAAQAGSHA 1255
P+ + PP P+K + P E E + P GE + + E S A
Sbjct: 1719 PETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATG---- 1774
Query: 1256 THPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQD 1315
P TS L P++V+A +P K + A +A GG S +
Sbjct: 1775 -QPATSRLP-----KARPTKVKA-----EPPPKKRKKWLKEAGGNATAGGGPPGSSSDSE 1823
Query: 1316 GAAGVP 1321
+ G P
Sbjct: 1824 SSPGAP 1829
Score = 59.3 bits (142), Expect = 3e-08
Identities = 67/250 (26%), Positives = 88/250 (35%), Gaps = 34/250 (13%)
Query: 837 MSPEKSHRVISPSSGYSSQSN-TPTALTPVP--------VFLKSVSPANGKGKPKP--KV 885
+SP KS P+ G Q TP P P + S G G P P ++
Sbjct: 1307 LSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRL 1366
Query: 886 PERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFP--CP 943
E + ++ SS S + + + ++ A+ PP P +P P P
Sbjct: 1367 DEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAP 1426
Query: 944 ADRSPFLPPPPPVTDCSQGSPLPHSPVF----PPPPPEALIPFCSPPDWCLSPPRPALSP 999
A P PPP P + + P P+ PP PP A P PP PP P P
Sbjct: 1427 AAAVPG-PPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP-----PPPPPPQP 1480
Query: 1000 ILPDSPV------SLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRP 1053
LP P S P PPPL PPP PP P P P + P
Sbjct: 1481 ALPSPPPLVAPTPSSPPPPPL-----PPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535
Query: 1054 PSTKEETSRP 1063
+ +RP
Sbjct: 1536 EDPELPDTRP 1545
Score = 45.4 bits (106), Expect = 4e-04
Identities = 69/230 (30%), Positives = 79/230 (34%), Gaps = 61/230 (26%)
Query: 962 GSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPP-LLPS--S 1018
G+ L SP PPPPP A +P L P D P+ LP PPP LLPS S
Sbjct: 757 GAFLQKSP--PPPPPTAQSTQPTPHGLLLEAGGP-------DLPLVLPPPPPQLLPSVLS 807
Query: 1019 EPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQL 1078
P P K P T G P+ PP PPMPL QL
Sbjct: 808 HAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP--------PPMPL---------QL 850
Query: 1079 RPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSL 1138
++ G E P AP L+P L + E+ +P
Sbjct: 851 EAHLRSHGLE--------------PAAPSPRLRPEESLDPPGAMQELLGALEPLP----- 891
Query: 1139 PTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSP 1188
P P GD G GP S G AG A PSP T P P
Sbjct: 892 PAP------GDTGV-----GP-PNSEGKDPAG-AYRSPSPQGTKAPRFVP 928
Score = 44.7 bits (104), Expect = 7e-04
Identities = 36/124 (29%), Positives = 51/124 (41%), Gaps = 21/124 (16%)
Query: 951 PPPPPVTDCSQGSPL--------PHSPVFPPPPPEALIP--FCSPPDWCLSPPRPALSPI 1000
PPPPP +Q +P P P+ PPPP L+P P S + + +
Sbjct: 765 PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLL 824
Query: 1001 LPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEET 1060
P + P PPP PPP PP+ + R ++ +P + LRP EE+
Sbjct: 825 EPATRDGAPQPPP----PPPPPPPPMPLQLEAHLR---SHGLEPAAPSPRLRP----EES 873
Query: 1061 SRPP 1064
PP
Sbjct: 874 LDPP 877
Score = 43.9 bits (102), Expect = 0.001
Identities = 55/178 (30%), Positives = 67/178 (37%), Gaps = 41/178 (23%)
Query: 897 SISSSSTSLSSSTSTEGSGTMKKLDPAV--GSPPAPPPPPVPSPPFPC------------ 942
S+ S + S S S S G + L+PA G+P PPPPP P PP P
Sbjct: 804 SVLSHAPSPSPSASKVG---VHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLE 860
Query: 943 PADRSPFLPP-----PPPVTDCSQGS--PLPHSP---VFPPPPPEALIP---FCSPPDWC 989
PA SP L P PP G+ PLP +P PP E P + SP
Sbjct: 861 PAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQG 920
Query: 990 LSPPR--PALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPE 1045
PR P S PDS LL E P ++ F + +G PE
Sbjct: 921 TKAPRFVPLTSICFPDS---------LLQDEERSFFPTMEEMFGGGAADDYGKAGPPE 969
Score = 43.9 bits (102), Expect = 0.001
Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 9/113 (7%)
Query: 954 PPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPP 1013
P T G PL + P PPP +P + P P P+L + P P P P
Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSN----GTPEP---PLLEEKPPPTPPPAP 1465
Query: 1014 LLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMP 1066
P +PPP PP P+ + PP L PP S PP P
Sbjct: 1466 T-PQPQPPP-PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP 1516
Score = 42.4 bits (98), Expect = 0.004
Identities = 90/376 (23%), Positives = 124/376 (32%), Gaps = 74/376 (19%)
Query: 877 GKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVP 936
G+ K K K PER + L++S G+G + SPP PPP
Sbjct: 723 GRLKEKKKGPERGGE---------TPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQS 773
Query: 937 SPPFP-------CPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPP--D 987
+ P P D LPPPPP S L H+P P + + P D
Sbjct: 774 TQPTPHGLLLEAGGPDLPLVLPPPPPQL---LPSVLSHAPSPSPSASKVGVHLLEPATRD 830
Query: 988 WCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPP--PAPPLDPKFMKDTRPPFTNSGQPE 1045
PP P P P P+ L L L P P+P L P+ D PP G +
Sbjct: 831 GAPQPPPP---PPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD--PP----GAMQ 881
Query: 1046 SSRGSLR--PPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTA------ 1097
G+L PP+ + PP +E G +A + T+
Sbjct: 882 ELLGALEPLPPAPGDTGVGPP----NSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDS 937
Query: 1098 ---QEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDH---- 1150
E+R+ + E E P + P P G +
Sbjct: 938 LLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGR 997
Query: 1151 --GSAAERGG---PVSRSPGAPS-----------AGEAEARPSPSTTPLPDSSPSRKP-- 1192
G+ E G ++ P PS +G +A P P P P +P+ +P
Sbjct: 998 ASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKG 1057
Query: 1193 ---PPI--SKKPKLFL 1203
PI S KPK L
Sbjct: 1058 GLTSPIFCSTKPKKLL 1073
Score = 41.6 bits (96), Expect = 0.006
Identities = 164/741 (22%), Positives = 228/741 (30%), Gaps = 196/741 (26%)
Query: 714 GKSGSSPSQSPC---SDLEEPWLPRSR-SQSTVSAGSSMTSA----TTPNVYSLCGATPS 765
G +G P+Q+P + P PR +Q + A SS +A ++P +Y+ GA P
Sbjct: 215 GPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPG 274
Query: 766 QSDTS-------SVKSEYTDPWG--------------YYIDYTGMQEDPGN-------PA 797
+V Y P +Y+ G G+ P
Sbjct: 275 PPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPL 334
Query: 798 GGCSTSSGV--PTGNGPVRHVQEGS-RATMPQVPGGS--------VKPKIMSPEKSHRVI 846
GG S G P+ GP S RAT P+ GG +P I SP
Sbjct: 335 GGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYK---- 390
Query: 847 SPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTS-- 904
+ GY + + T P P + G P K+S + S
Sbjct: 391 TGKGGYGAAAGGATR--PPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQP 448
Query: 905 ---LSSSTSTEGSG-----TMKKLDPAVGSPPAPP--PPP-------------------- 934
L +G G + K G PP PP PPP
Sbjct: 449 QGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYG 508
Query: 935 VPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVF----------------PPPPPEA 978
V P+P PA S LP P S G HSP P
Sbjct: 509 VQGEPYPGPAAHSQGLPTASPSLSYSTG----HSPALSGHGGGWGPSSLGGGGEASPSHI 564
Query: 979 LIPFCSPPDWCLSP-------PRPALSPILPDSPVSLPLPPP------------------ 1013
+ P SPP P P LS +L +P L PP
Sbjct: 565 IRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPF---LAPPGAGSYAAGAGGYKGKGDG 621
Query: 1014 --LLPSSEPPPAPPLDPK------FMKDTRPPFTN--------SGQPESSR------GSL 1051
LL PPA + + ++ PP T+ G ++S+ G+
Sbjct: 622 SELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAG 681
Query: 1052 RPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAA------QLSERTAQEQRTPVA 1105
PP T E ++ LQ V + GA AA +L E+ +R
Sbjct: 682 GPPGTPYELAKEDP---QRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGET 738
Query: 1106 PQ----YHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGP-- 1159
P+ + A K + + P + S+ PTP HG E GGP
Sbjct: 739 PEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTP--------HGLLLEAGGPDL 790
Query: 1160 --VSRSPG---APSAGEAEARPSPSTTPL---------PDSSPSRKPPPISKKPKLFLVV 1205
V P PS PSPS + + D +P PPP P + L +
Sbjct: 791 PLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQL 850
Query: 1206 PPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHS-REAKESSAAQAGSHATHPGTSVLE 1264
+ +EPA + + R P + G++ A E G P S +
Sbjct: 851 EAHLRSHGLEPA---APSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGK 907
Query: 1265 GGAAGSMSPSRVEANVPMVQP 1285
A SPS P P
Sbjct: 908 DPAGAYRSPSPQGTKAPRFVP 928
Score = 39.7 bits (91), Expect = 0.024
Identities = 67/304 (22%), Positives = 104/304 (34%), Gaps = 35/304 (11%)
Query: 1012 PPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTE 1071
PPL + PP P PK + + P QP ++ PP + + +E
Sbjct: 1296 PPLYQAGLTPPLSP--PKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESE 1353
Query: 1072 ALQMVQLRPVRKNSGAEAAQLSERTA--QEQRTPVAPQYHLKPSAFLKSRNSTNEMESES 1129
L + P ++ L + ++ VA L+ S + S S + +
Sbjct: 1354 GLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQES--ISSAISALDDPPLA 1411
Query: 1130 QPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPS 1189
P TS+ P + + G G P + S G P E +P P+ P P P
Sbjct: 1412 GPKD-TSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQ 1470
Query: 1190 RKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAA 1249
PPP +P L P P A P+ L P P A
Sbjct: 1471 PPPPPPPPQPAL----PSPPPLVAPTPSSPPPPPLPPPPPP-----------------AM 1509
Query: 1250 QAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQE------EPAENSADT 1303
+ P + L +PS + +P +P + A KQE E E + ++
Sbjct: 1510 PSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRP-LHLAKKQETAAVCGETDEEAGES 1568
Query: 1304 GGDG 1307
GG+G
Sbjct: 1569 GGEG 1572
Score = 38.5 bits (88), Expect = 0.053
Identities = 60/245 (24%), Positives = 85/245 (34%), Gaps = 37/245 (15%)
Query: 966 PHSPVFPPPPPEALIPF---CSPPDWCLSPPRPALS------PILPDS----PVSLPLPP 1012
P + PPP P A P+ C P P L P LP + P+ L
Sbjct: 974 PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSG 1033
Query: 1013 PLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEA 1072
P + PPP PP PP + +P +G L P S P L+ T +
Sbjct: 1034 PHQAAPPPPPPPP----------PPPAPASEP---KGGLTSPIF---CSTKPKKLLKTSS 1077
Query: 1073 LQMVQLR-PVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQP 1131
+++ R P + AQ E A E + V L P +S + S
Sbjct: 1078 FHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPL 1137
Query: 1132 ASVTSSLPTPAKSS--SQGDHGSAAERGGPVSRSPGAPSAGEAE----ARPSPSTTPLPD 1185
+ P P +G + A+R GP R G P E A P+ ++TP
Sbjct: 1138 GDIDFCPPNPGPDGPRRRGRKPTKAKRDGP-PRPRGRPRIRPLEVPTTAGPASASTPTDG 1196
Query: 1186 SSPSR 1190
+ R
Sbjct: 1197 AKKPR 1201
Score = 37.0 bits (84), Expect = 0.15
Identities = 50/177 (28%), Positives = 62/177 (35%), Gaps = 39/177 (22%)
Query: 905 LSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSP 964
L S+ + E G ++ G A PPPP P PP P PA P +T
Sbjct: 1018 LPSTVNAEPLGLIQS-----GPHQAAPPPPPPPPPPPAPASE-----PKGGLT------- 1060
Query: 965 LPHSPVFPPPPPEALI-------------PFCSPPDWCLSPPRPALSPILPDSPVSLPLP 1011
SP+F P+ L+ PF +P D P + L
Sbjct: 1061 ---SPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLN 1117
Query: 1012 PPLLPS--SEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMP 1066
P LP S P L P D PP N G P+ R R P TK + PP P
Sbjct: 1118 PRRLPDLVSSCRSRPALSPLGDIDFCPP--NPG-PDGPRRRGRKP-TKAKRDGPPRP 1170
Score = 33.9 bits (76), Expect = 1.3
Identities = 125/544 (22%), Positives = 169/544 (31%), Gaps = 73/544 (13%)
Query: 847 SPSSGYSSQSNTPTALTPVPVFLKSVSP-----ANGKGKPKPKVPERKSSLISSVSISSS 901
S S Y ++ + PVP L P ANG P V K S +V S
Sbjct: 146 SALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHD-VLHLKPSQAPTVPSSLG 204
Query: 902 STSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQ 961
L+ +G L PA P P PP P PP P + Q
Sbjct: 205 FERLAGGGVLGPAG----LGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQ 260
Query: 962 GSPLPH--SPVFP-PPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSS 1018
SP + S P PPPPE + PR P S PPP
Sbjct: 261 SSPQLYNFSGAAPGPPPPERAL------------PRQDTVIKHYQRPASAQPPPP----- 303
Query: 1019 EPPPAPPLDPKFMKDTRPPFT--NSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMV 1076
PPPA L P + S G P E S+ T A
Sbjct: 304 -PPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRA 362
Query: 1077 QLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAF-LKSRNSTNEMESESQPASVT 1135
GA R + +P Y + + +T S
Sbjct: 363 TGPEAAGGGGAGGGGGGYRPIIQ-----SPGYKTGKGGYGAAAGGATRPPPPRSTATPKC 417
Query: 1136 SSLPTPAKSSSQGDHGSAAERGGPVSRSPGAP-------------SAGEA-EARPSPSTT 1181
SL PA + + G A GG + SPG P G+A + +PS +
Sbjct: 418 QSLGGPAAAYATGKASGAGGAGGQ-AYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYS 476
Query: 1182 PLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSR 1241
P PS PPP + + + + V+ A + PT S +
Sbjct: 477 GGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTG 536
Query: 1242 EAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSA 1301
+ S H G S L GG G SPS + ++P SP P S
Sbjct: 537 HSPALS-----GHGGGWGPSSLGGG--GEASPSHI------IRPLQSPPATGRPPGVGS- 582
Query: 1302 DTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFL-KEDGNDEVMTPSRP---RTTEDLF 1357
G G+ S A + A ++ A + K DG++ + P P RT ++ F
Sbjct: 583 -PGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEF 641
Query: 1358 AAIH 1361
H
Sbjct: 642 LIQH 645
Score = 31.6 bits (70), Expect = 6.5
Identities = 46/174 (26%), Positives = 60/174 (34%), Gaps = 16/174 (9%)
Query: 983 CSPPDWCLSPPRPALSPILPDSPVSL---PLPPPLLPSSEPPPAPPLDPKFMKDTRPPFT 1039
C+ W PP P +PVS PPP P+ PPP P K + P T
Sbjct: 1662 CARKPWH-RPPVPVRRSGQAKNPVSAGGSSAPPPKAPA--PPPKPETPEKTTSEKPPEQT 1718
Query: 1040 -NSGQPE----SSRGSLRP---PSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQ 1091
+ PE LRP KE+ +R PL A Q RP R + + A
Sbjct: 1719 PETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPAT 1778
Query: 1092 LSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSS 1145
A+ + P K +LK N P S + S +P S
Sbjct: 1779 SRLPKARPTKVKAEPP-PKKRKKWLKEAGG-NATAGGGPPGSSSDSESSPGAPS 1830
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 86.7 bits (213), Expect = 2e-16
Identities = 113/424 (26%), Positives = 160/424 (37%), Gaps = 74/424 (17%)
Query: 922 PAVGSPPAPPPPPVPSPPFP------CPADRSPFLPPPP-----PVTDCSQGSPLPHSPV 970
P S +PPP +P+ P P P + SP PPP P + S SPL SP+
Sbjct: 461 PPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPL 520
Query: 971 FPP---PPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLD 1027
PP PP AL SPP P LSP +SP+S PP LP+S PP A L
Sbjct: 521 SPPEESPPSPALETPLSPP-----PEASPLSPPFEESPLS--PPPEELPTSPPPEASRLS 573
Query: 1028 PKFMKD--TRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNS 1085
P + + PP + P L PP + S PP + L P
Sbjct: 574 PPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP---------EESPLSP----- 619
Query: 1086 GAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSS 1145
EA++LS +P + + P + SR S + S P S L P + S
Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPPEV-SRLSPLPVVSRLSPPPEESPLSPPPEES 678
Query: 1146 SQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTT------------PLPDS---SPSR 1190
A+ P SP +P ++ A P P + PLP+ P
Sbjct: 679 PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
Query: 1191 KPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQ 1250
+ P +S +P+ + P P++ AE P P EE + + + + Q
Sbjct: 739 EGPHLSPRPEEPHLSPRPEEPHLSPQAEEP----HLSPQP---EEPCLCAVPEEPHLSPQ 791
Query: 1251 AGSHATHPGTSVLEGGAAGSMSPSRVEANVPMV--QPDVSPAPKQEEPAENSADTGGDGE 1308
A P L +SP E ++ V +P +SP P++ + S E
Sbjct: 792 AEGPHLSPQPEELH------LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE------E 839
Query: 1309 SCLS 1312
CLS
Sbjct: 840 PCLS 843
Score = 74.7 bits (182), Expect = 7e-13
Identities = 90/331 (27%), Positives = 124/331 (37%), Gaps = 50/331 (15%)
Query: 919 KLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEA 978
+L+P + +P P +P P + SP PPP SP PPP
Sbjct: 425 QLEPQLEAPLNEEMPLLPPP------EESPLSPPPE------------ESPTSPPPEASR 466
Query: 979 LIPFCSPPDWCLSPPRPA---LSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTR 1035
L P PP+ + P P LS L +SP+S PP P S PP + P P
Sbjct: 467 LSP---PPEELPASPLPEALHLSRPLEESPLS--PPPEESPLSPPPESSPFSPLEESPLS 521
Query: 1036 PPFTN----------SGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNS 1085
PP + S PE+S L PP + S PP L T+ + +L P
Sbjct: 522 PPEESPPSPALETPLSPPPEAS--PLSPPFEESPLSPPPEELPTSPPPEASRLSP----- 574
Query: 1086 GAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSS 1145
E + +S + +P L P F +S S ES P S L P + S
Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFP-PFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633
Query: 1146 SQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPL---PDSSPSRKPPP---ISKKP 1199
+ P S +P + P P +PL P+ SP+ PP +S P
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP 693
Query: 1200 KLFLVVPPPQKDFAVEPAENVSEALRAVPSP 1230
+ PPP+ A P E+ +L SP
Sbjct: 694 EDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724
Score = 73.2 bits (178), Expect = 2e-12
Identities = 125/492 (25%), Positives = 174/492 (35%), Gaps = 65/492 (13%)
Query: 839 PEKSHRVISPSSGYSSQSNTPTALTPV-PVFLKSVSPANGKGKPKPKVPERKSSLISSVS 897
PE+S PS + + P +P+ P F +S P + + P P ++S +S
Sbjct: 523 PEES----PPSPALETPLSPPPEASPLSPPFEES--PLSPPPEELPTSPPPEASRLSPPP 576
Query: 898 ISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPP---PVPSPP----FPCPADRSPFL 950
S + + +L P P PPP P+ PP P + SP
Sbjct: 577 EESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMS 636
Query: 951 PPP-----PPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRP---ALSPILP 1002
PPP P + S+ SPLP PPP E+ P PP+ + P P LSP
Sbjct: 637 PPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES--PLSPPPEESPTSPPPEASRLSPPPE 694
Query: 1003 DSPVSLP------LPPP-----LLPSSEPPPAP-PLDPKFMKDTRPPFTNSGQPESSRGS 1050
DSP S P PPP LP E P P P +P+ + P S +PE S
Sbjct: 695 DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL-SPRPEEPHLS 753
Query: 1051 LRP--PSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQY 1108
RP P + P + E + AE LS + + +P +
Sbjct: 754 PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813
Query: 1109 HLKPSAFLKSRNSTNEMESESQPASVTSSL-PTPAKSSSQGDHGSAAERGGPVSRSPGAP 1167
HL P + E ES P S L P P +S H S P+S P P
Sbjct: 814 HLSPVPEEPCLSPQPE-ESHLSPQSEEPCLSPRPEES-----HLSPELEKPPLSPRPEKP 867
Query: 1168 SAGEAEARPSPSTTPL--PDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALR 1225
+ P+P PL P PS P L+ P + P + E L
Sbjct: 868 PEEPGQC-PAPEELPLFPPPGEPSLSP----------LLGEPALSEPGEPPLSPLPEELP 916
Query: 1226 AVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVL-----EGGAAGSMSPSRVEANV 1280
PS + + + + A P S L GA G P A
Sbjct: 917 LSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLA-A 975
Query: 1281 PMVQPDVSPAPK 1292
P+++ +SP P+
Sbjct: 976 PILETPISPPPE 987
Score = 70.5 bits (171), Expect = 1e-11
Identities = 109/441 (24%), Positives = 155/441 (35%), Gaps = 79/441 (17%)
Query: 923 AVGSPPAPPPPPV----PSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSP--VFPPPPP 976
A+GSPP P + P+ P FL PP + P P SP +F PP
Sbjct: 2112 ALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPP------AGSVPGPDSPGELFLKLPP 2165
Query: 977 EALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRP 1036
+ S + L+P P L P P +P + P P P AP P +RP
Sbjct: 2166 QVPAQVPSQDPFGLAPAYP-LEPRFPTAPPTYP------PYPSPTGAPAQPPMLGASSRP 2218
Query: 1037 PFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERT 1096
+GQP + PP T P P + + L V ++ G + SE
Sbjct: 2219 ---GAGQPGEFHTT--PPGTPRHQPSTPDPFLKPRCPSLDNL-AVPESPGVGGGKASEPL 2272
Query: 1097 AQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTP---AKSSSQGDHGSA 1153
L P F +SR + E++ E AS S P S S G H
Sbjct: 2273 -------------LSPPPFGESRKAL-EVKKEELGASSPSYGPPNLGFVDSPSSGTHLGG 2318
Query: 1154 AERGGP-VSRSPGAPSAGEAEAR------------PSPSTTPLPDSSPS----------R 1190
E P V ++P P A + E + P+ + P P S P
Sbjct: 2319 LELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPY 2378
Query: 1191 KPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQ 1250
PP++ +P+ PPP+ A+ P S+ VP+ + S + SA
Sbjct: 2379 AQPPLTPRPQ----PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAE- 2433
Query: 1251 AGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESC 1310
+ P T + S PSR ++ P P P +P E + G +
Sbjct: 2434 --AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP---QPPEVAFKAGSLAHTS 2488
Query: 1311 LSQQDGAAGVPETNAAGSSSE 1331
L GA G P AG + E
Sbjct: 2489 L----GAGGFPAALPAGPAGE 2505
Score = 65.5 bits (158), Expect = 4e-10
Identities = 159/642 (24%), Positives = 218/642 (33%), Gaps = 119/642 (18%)
Query: 672 PLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQSPCSDLEEP 731
P P DSL +P L ES + L QL P G S P EEP
Sbjct: 706 PASPPPEDSLMSLP----------LEESPLLPLPEEPQLC-PRSEGPHLSPRP----EEP 750
Query: 732 WL-PRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQ 790
L PR + P LC + + + P + +
Sbjct: 751 HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQT 810
Query: 791 EDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSS 850
E+P P P Q PQ + P+ PE+SH +SP
Sbjct: 811 EEPHLS----------PVPEEPCLSPQPEESHLSPQSEEPCLSPR---PEESH--LSPEL 855
Query: 851 GYSSQSNTPT------ALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTS 904
S P P P L + P G+ P + E S +S
Sbjct: 856 EKPPLSPRPEKPPEEPGQCPAPEELP-LFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEE 914
Query: 905 LSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSP 964
L S S E S SP PP P+P P P +P P + G+
Sbjct: 915 LPLSPSGEPSL----------SPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAK 964
Query: 965 LPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPP--PLLPSSEPPP 1022
P P P P PP+ + P P ILP SP S P+ P P+L PP
Sbjct: 965 GDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS-PVGPASPILMEPLPPQ 1023
Query: 1023 APPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVR 1082
PL +S P++S PPS + S P +PL L P+
Sbjct: 1024 CSPL-----------LQHSLVPQNS-----PPS---QCSPPALPLSVPSPLS-----PIG 1059
Query: 1083 KNSG-AEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTP 1141
K G ++ A+L E ++ P P L+PSA T+ + S S + P P
Sbjct: 1060 KVVGVSDEAELHEMETEKVSEPECPA--LEPSA-------TSPLPSPMGDLSCPAPSPAP 1110
Query: 1142 AKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKL 1201
A G A G +PG ++P P TP +S + P + +L
Sbjct: 1111 ALDDFSGLGEDTAPLDG--IDAPG--------SQPEPGQTPGSLASELKGSPVLLDPEEL 1160
Query: 1202 FLVVP----PPQKDFAVE--PAENVSEALRAV-PSPTTGEEGSVHSREAKESSAAQAGSH 1254
V P P K A + P E E V P+P T + + + + S+ +Q +
Sbjct: 1161 APVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVN---EISNLSQGDAS 1217
Query: 1255 ATHPGTSVL------EGGAAGSMSPSRVEANVPMVQPDVSPA 1290
A+ PG+ L EGG + SM V DVSPA
Sbjct: 1218 ASFPGSEPLLGSPDPEGGGSLSMELG--------VSTDVSPA 1251
Score = 60.1 bits (144), Expect = 2e-08
Identities = 166/715 (23%), Positives = 238/715 (33%), Gaps = 104/715 (14%)
Query: 783 YIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKS 842
Y TG P +G P G G+ P P +KP+ P
Sbjct: 2199 YPSPTGAPAQPPMLGASSRPGAGQP---GEFHTTPPGTPRHQPSTPDPFLKPRC--PSLD 2253
Query: 843 HRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGK----GKPKPKVPERKSSLISSVSI 898
+ + S G + L+P P F +S K G P + S S
Sbjct: 2254 NLAVPESPGVGGGKASEPLLSPPP-FGESRKALEVKKEELGASSPSYGPPNLGFVDSPSS 2312
Query: 899 SSSSTSLSSSTS-------TEGSGTMKKLDPAVGSPPAPPPPP---VPSPPFPCPADRSP 948
+ L T T + ++ P +G P PPP PSPP P
Sbjct: 2313 GTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPP------SHP 2366
Query: 949 FLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVS- 1007
+ P TD PL P PPPPE+ C PPR LP P S
Sbjct: 2367 DIFRPGSYTDPYAQPPLTPRP--QPPPPESC---------CALPPRS-----LPSDPFSR 2410
Query: 1008 LPLPPPLLPSSEPP--PAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETS---- 1061
+P P SS+ P P P F P S P S RPPS +
Sbjct: 2411 VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS-----RPPSRPQSRDPFAP 2465
Query: 1062 --RPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSR 1119
+PP P A + L +G A L A E V +P F++S
Sbjct: 2466 LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSG---QPPNFVRSP 2522
Query: 1120 NSTNEMESES-------QPASVTSSLPTPAKSSSQGDHGSAAERG-GPVSRSPGAPSAGE 1171
+ + + S Q S P + HG + G GP P + +
Sbjct: 2523 GTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTV 2582
Query: 1172 AEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPT 1231
A PS +PL SS S + V+PPP D ++ + + + SP
Sbjct: 2583 ATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSP- 2641
Query: 1232 TGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAP 1291
V RE + + + A PGT + G +G S+ E + +
Sbjct: 2642 ------VEKREDPGTGMGSSLATAELPGTQ--DPGMSGL---SQTELEKQRQRQRLRELL 2690
Query: 1292 KQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPR 1351
+++ N T + + GA G P + A SS A + L TP
Sbjct: 2691 IRQQIQRN---TLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRG-----QTPFAGT 2742
Query: 1352 TTEDLFAAIHRSKRK--VLGRRD--SDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQR 1407
+ + SK +LG SDD SR P PP TP ++ + S + VG Q
Sbjct: 2743 QDKSSLVGLPPSKLSGPILGPGSFPSDDRLSR---PPPPATP--SSMDVNSRQLVGGSQA 2797
Query: 1408 SIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPSPDAPE 1462
+++ +L L++ + + + A T RF S PS PE
Sbjct: 2798 FYQRAPYPG----SLPLQQQQQQLWQQQQATAA----TSMRFAMSARFPSTPGPE 2844
Score = 58.9 bits (141), Expect = 4e-08
Identities = 69/280 (24%), Positives = 96/280 (34%), Gaps = 28/280 (10%)
Query: 959 CSQGSPLPHSPVFPPPPPEALIPFCSPPD-----WCLSP--PRPALSPILPDSPVSLPLP 1011
CS+ SP P P P+AL C + P P P P + L
Sbjct: 369 CSRFSP-PEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLE 427
Query: 1012 PPL-------LPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPP 1064
P L +P PP PL P PP + P L PP + S P
Sbjct: 428 PQLEAPLNEEMPLLPPPEESPLSP-------PPEESPTSPPPEASRLSPPPEELPASPLP 480
Query: 1065 MPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNE 1124
L + L+ L P + S S + + +P++P PS L++ S
Sbjct: 481 EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP 540
Query: 1125 MESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTT--- 1181
S P S L P + A+ P SP +P E+ P P +
Sbjct: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF 600
Query: 1182 PLPDSSPSRKPP---PISKKPKLFLVVPPPQKDFAVEPAE 1218
P + SP PP P+S P+ + PPP+ P E
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE 640
Score = 55.1 bits (131), Expect = 5e-07
Identities = 130/549 (23%), Positives = 181/549 (32%), Gaps = 127/549 (23%)
Query: 826 QVPGGSVKP---KIMSPEKSHRVISPSSGYSSQSNTPTAL------TPVPVFLKSVSPAN 876
+VP P K +HR+ SQ N T + T P + P
Sbjct: 2051 KVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQP 2110
Query: 877 GK-GKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPP---- 931
G G P P + ++ I S +T STS +G L P GS P P
Sbjct: 2111 GALGSPPP-------AAAPTIFIGSPTTPAGLSTSADGF-----LKPPAGSVPGPDSPGE 2158
Query: 932 -----PPPVP---------------------------SPPFPCPADRSPFLPPPPPVTDC 959
PP VP PP+P P P PP+
Sbjct: 2159 LFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTG----APAQPPMLGA 2214
Query: 960 SQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPI-LPDSP------VSLPL-- 1010
S F PP S PD L P P+L + +P+SP S PL
Sbjct: 2215 SSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLS 2274
Query: 1011 PPPL-------------LPSSEPPPAPPLDPKFMKDTRPPFTNSG-----QPESSRGSLR 1052
PPP L +S P PP + F+ D+ T+ G P+ + L
Sbjct: 2275 PPPFGESRKALEVKKEELGASSPSYGPP-NLGFV-DSPSSGTHLGGLELKTPDVFKAPLT 2332
Query: 1053 PPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKP 1112
P +++ E P + L E L P S + + T + P+ P+ P
Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAP-SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
Query: 1113 SAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEA 1172
S + S P+ S +P +S S S+SP P A
Sbjct: 2392 P------ESCCALPPRSLPSDPFSRVPASPQSQSS-------------SQSPLTPRPLSA 2432
Query: 1173 EA-RPSPSTTPLPDSSPSRKPP--PISKKPKLFLVVP----PPQKDFAVEPAENVSEALR 1225
EA PSP T P +PP P S+ P L P PP+ F + S
Sbjct: 2433 EAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAG 2492
Query: 1226 AVPSP-TTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQ 1284
P+ G G +H++ + Q + PGT G G+ SP R + +
Sbjct: 2493 GFPAALPAGPAGELHAK----VPSGQPPNFVRSPGT----GAFVGTPSPMRFTFPQAVGE 2544
Query: 1285 PDVSPAPKQ 1293
P + P Q
Sbjct: 2545 PSLKPPVPQ 2553
Score = 48.5 bits (114), Expect = 5e-05
Identities = 166/770 (21%), Positives = 254/770 (32%), Gaps = 131/770 (17%)
Query: 797 AGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQS 856
+G S +S VP H+ ++ PG S+ ++ P++ P Q+
Sbjct: 4121 SGSSSEASSVP-------HLLAQPSVSLGDQPG-SMTQNLLGPQQ------PMLERPMQN 4166
Query: 857 NT-PTALTPVPVFLKSVSPANGKGKP----KPKVPERKSSLISSVSISSSSTSLSSSTST 911
NT P P PV +G+G P P V + ++ L ++ + LS
Sbjct: 4167 NTGPQPPKPGPVL------QSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQ 4220
Query: 912 EGSGTMKKLD----PAVGSPPAPPPPPVPSPPFPCPADRSPFL-----PPPPPVTDCSQG 962
+ + + AV P P + P P L P P+ + G
Sbjct: 4221 QLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAG 4280
Query: 963 SPLPHSPVFPPPPPEALI--PFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPS-SE 1019
P P P P PP AL P P + P P SP P P LP P LP+ ++
Sbjct: 4281 -PRPQGPPRLPAPPGALSTGPVLGP----VHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQ 4335
Query: 1020 PPPAPPLDPKFMKDTRPPFTNSGQPESSR----------GSLRPPSTKEETSRPPMPLIT 1069
PP P PK T P P +++ G PP ET +P +
Sbjct: 4336 LPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLV 4395
Query: 1070 TEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAF---LKSRNSTNEM- 1125
L V + V EA+QLS + + +K A + + ++N +
Sbjct: 4396 PGHLDQVNGQVV-----PEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLL 4450
Query: 1126 --ESESQPASVTSSLPTPAK----SSSQGDHGSAAERGGPV--------SRSPGAPSAGE 1171
S+ + AK S+ +G G AE G + + G PS E
Sbjct: 4451 LAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKE 4510
Query: 1172 AEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPT 1231
A P TP P +S + KL +K+ V +E + + L+ S
Sbjct: 4511 DAAARKP-LTPKPKRVQKASDRLVSSRKKL-------RKEDGVRASEALLKQLKQELSLL 4562
Query: 1232 TGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVE-----------ANV 1280
E ++ A S A GS G S L G P+ + +N
Sbjct: 4563 PLTEPAI---TANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNP 4619
Query: 1281 PMVQPDVSPAP------KQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGS------ 1328
P + P P K S + G + S +D + +T+ S
Sbjct: 4620 PTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAA 4679
Query: 1329 -----SSEACDFLKE-----DGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHS 1378
++ D E D D ++ S P + L R GR + +D
Sbjct: 4680 LPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESI--LGEEAPRFPHLGSGRWEQED--- 4734
Query: 1379 RNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMS- 1437
R SP P+ P + P K G++ + +KG S+ S ++
Sbjct: 4735 RALSPVIPLIPRASIPVFPDTKPYGALGLEV------PGKLPVTTWEKGKGSEVSVMLTV 4788
Query: 1438 AAEMLKNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMP 1487
+A KN + S P S P RA E K E P
Sbjct: 4789 SAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGP 4838
Score = 41.2 bits (95), Expect = 0.008
Identities = 33/110 (30%), Positives = 40/110 (36%), Gaps = 16/110 (14%)
Query: 928 PAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPD 987
PAP PP S + L PPP SPL SP PP P +P
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELP------ 4937
Query: 988 WCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPP 1037
+ L + PV PLP P S P P+ +D+RPP
Sbjct: 4938 ----------TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
Score = 37.0 bits (84), Expect = 0.15
Identities = 48/171 (28%), Positives = 65/171 (38%), Gaps = 41/171 (23%)
Query: 951 PPPPPVTDCSQGSPLPHSPV--FPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSL 1008
P P P T S + + V PPPE P P SP+ P SP S
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEE--------------PSPPPSPLAP-SPASP 4928
Query: 1009 PLPP----PLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPP 1064
P P P P +EPP PL P +S + + RPP E+ SRPP
Sbjct: 4929 PTEPLVELPTEPLAEPPVPSPL----------PLASSPESARPKPRARPPEEGED-SRPP 4977
Query: 1065 MPLITTEALQMVQLR---PVRKNSG-----AEAAQLSERTAQEQRTPVAPQ 1107
L + ++ +LR ++K SG E A+ E+ R P+
Sbjct: 4978 R-LKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRPDKVPR 5027
Score = 35.0 bits (79), Expect = 0.58
Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 16/104 (15%)
Query: 891 SLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFL 950
SL+ S + + S T + +++L P+PPP P+ SP
Sbjct: 4877 SLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAP---------SPAS 4927
Query: 951 PPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPR 994
PP P+ + LP P+ PP P L P S P+ PR
Sbjct: 4928 PPTEPLVE------LPTEPLAEPPVPSPL-PLASSPESARPKPR 4964
Score = 32.0 bits (71), Expect = 5.0
Identities = 76/325 (23%), Positives = 108/325 (33%), Gaps = 52/325 (16%)
Query: 1011 PPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITT 1070
P PL P PPPA D P S PE ++P EE R P P T
Sbjct: 3091 PGPLGPEERPPPA--------ADASEPRLASVLPE-----VKP--KVEEGGRHPSPCQFT 3135
Query: 1071 EALQMVQLRPVRKNSGAEAAQ-LSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESES 1129
A V+ P + G S +++ R P S T E S
Sbjct: 3136 IATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGP---------FSSSGHTAEKASFG 3186
Query: 1130 QPASVTSSLPTPAKSSSQGDHG--SAAERGGPVSRSPGAPSAGEAEARPSPST---TPLP 1184
+ L TP+ S G E PG P+A E S+ + LP
Sbjct: 3187 ATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELP 3246
Query: 1185 ---DSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSR 1241
+ + + KK +L + P Q+ + + +L + P P S
Sbjct: 3247 LLIEDLLEHEKKELQKKQQLSAQLQPAQQ----QQQQQQQHSLLSAPGP-----AQAMSL 3297
Query: 1242 EAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSA 1301
+ SS + AGS L G AG+ P + +P P Q+ A + A
Sbjct: 3298 PHEGSSPSLAGSQ------QQLSLGLAGARQPGLPQPLMPTQPP---AHALQQRLAPSMA 3348
Query: 1302 DTGGDGESCLSQQDGAAG-VPETNA 1325
G Q G AG VP+ ++
Sbjct: 3349 MVSNQGHMLSGQHGGQAGLVPQQSS 3373
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 84.7 bits (208), Expect = 6e-16
Identities = 137/653 (20%), Positives = 212/653 (32%), Gaps = 64/653 (9%)
Query: 664 SLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQ- 722
S++K L P+ + PK + G L T + + + ++P +
Sbjct: 178 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-----TPKEPTPTTPKEPASTTPKEP 232
Query: 723 SPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGY 782
+P + P P+ + +T + + P T + + E
Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 292
Query: 783 YIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKS 842
T + P P T+ P P + T P+ P + K + K
Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-----KEPTPTTPKEPAPTTKEPAPTTPKE 347
Query: 843 HRVISPSSGYSSQSNTPTALTP---VPVFLKSVSPANGKGKPKPKVPERKSSLISSVSIS 899
+P + P TP P K SP K +P KS+ ++ +
Sbjct: 348 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPA 404
Query: 900 SSSTSLSSSTSTEGSGTMKKLDPAVGSP--PAPPPPPVPSPPFPC-PADRSPFLPPPPPV 956
++T + +T E S T K +PA +P PAP P P+P P PA +P P P
Sbjct: 405 PTTTKSAPTTPKEPSPTTTK-EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463
Query: 957 TDCSQGSPLPHSPVFP----PPPPEALIPFCSPPDWCLSPPRPA------LSPILPDSPV 1006
+ +P +P P P P+ L P +P +PA L+P P+ P
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523
Query: 1007 SLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMP 1066
P P + P A P PK T P P+ P T T + P
Sbjct: 524 --PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKGTAP 580
Query: 1067 LITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEME 1126
E +P K + T ++ P P K +A +
Sbjct: 581 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP----KGTAPTTPKEPAPTTP 636
Query: 1127 SESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDS 1186
E P + + PT K P +P P+ E +P+TT P S
Sbjct: 637 KEPAPTTPKGTAPTTLKE--------------PAPTTPKKPAPKEL----APTTTKGPTS 678
Query: 1187 SPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKES 1246
+ S KP P + K P +PA E P PTT E + KE
Sbjct: 679 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE----TPPPTTSEVST--PTTTKEP 732
Query: 1247 SAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAEN 1299
+ + P S A SP E VP + + P+ A++
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPK--EPGVPTTKTPAATKPEMTTTAKD 783
Score = 49.7 bits (117), Expect = 2e-05
Identities = 95/470 (20%), Positives = 164/470 (34%), Gaps = 77/470 (16%)
Query: 1032 KDTRPPFTNSGQPESSRGSLRPPS-TKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAA 1090
K + P + +P + R SL P S T +ETS T E + G E
Sbjct: 111 KVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKT 170
Query: 1091 QLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDH 1150
++ T ++T L P++ + ++ + + PA T PTP
Sbjct: 171 TSAKETQSIEKTSAKD---LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE---- 223
Query: 1151 GSAAERGGPVSRSPGAP------SAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLV 1204
P S +P P SA P+P+TT ++P P +K+P
Sbjct: 224 --------PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP----- 270
Query: 1205 VPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLE 1264
P K EPA ++ P+PTT + +E ++ + T P
Sbjct: 271 APTTPK----EPAPTTTKE----PAPTTTKSAPTTPKEPAPTTPKKPAP--TTP------ 314
Query: 1265 GGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENS----ADTGGDGESCLSQQDGAAGV 1320
P+ P PAP +EPA + A T + + ++ A
Sbjct: 315 ------KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368
Query: 1321 PETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRN 1380
P+ A ++ E ++ T S P TT++ A +K ++ ++
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTT-TKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKE 425
Query: 1381 HSPSPPVTP---TGAAPSLASPKQVGSIQ------RSIRKSSTSSDNFKALLLKKGSRSD 1431
+P+ P P T P+ +PK+ + +K + ++ A K +
Sbjct: 426 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 485
Query: 1432 TSARMSAA--EMLKNTDPR----------FQRSRSEPSPDAPESPSSCSP 1469
T +++ E L T P + EP+P PE P+ +P
Sbjct: 486 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 535
Score = 40.4 bits (93), Expect = 0.014
Identities = 73/400 (18%), Positives = 135/400 (33%), Gaps = 37/400 (9%)
Query: 1103 PVAPQYHLKPSAFLKSRNS----------TNEMESESQPASVTSSLPTPAKSSSQGDHGS 1152
P+ P+ L P++ S T E + ++ S T + +Q +
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182
Query: 1153 AAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDF 1212
+A+ P S+ P+ P+ T + +P+ P S PK P K
Sbjct: 183 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK--EPTPTTIKSA 240
Query: 1213 AVEPAENVSEALRAV------PSPTTGEEGSVHSRE------AKESSAAQAGSHATHP-- 1258
P E ++ P+PTT +E + + + KE + S T P
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300
Query: 1259 --GTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPA----ENSADTGGDGESCLS 1312
T+ + P+ P PAP +EPA + A T + +
Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 360
Query: 1313 QQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRD 1372
++ A P+ A ++ E ++ T S P TT++ A +K ++
Sbjct: 361 PKEPAPTTPKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKE--PAPTTTKSAPTTPKE 417
Query: 1373 SDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDT 1432
++ +P+ P P P +P + K + K + T
Sbjct: 418 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477
Query: 1433 SARMSAAEMLKNTDPRFQRSRSEPSPD--APESPSSCSPS 1470
+ + +A K P + +P+ AP +P +P+
Sbjct: 478 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 517
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 84.7 bits (208), Expect = 6e-16
Identities = 137/653 (20%), Positives = 212/653 (32%), Gaps = 64/653 (9%)
Query: 664 SLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQ- 722
S++K L P+ + PK + G L T + + + ++P +
Sbjct: 219 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-----TPKEPTPTTPKEPASTTPKEP 273
Query: 723 SPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGY 782
+P + P P+ + +T + + P T + + E
Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 333
Query: 783 YIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKS 842
T + P P T+ P P + T P+ P + K + K
Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-----KEPTPTTPKEPAPTTKEPAPTTPKE 388
Query: 843 HRVISPSSGYSSQSNTPTALTP---VPVFLKSVSPANGKGKPKPKVPERKSSLISSVSIS 899
+P + P TP P K SP K +P KS+ ++ +
Sbjct: 389 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPA 445
Query: 900 SSSTSLSSSTSTEGSGTMKKLDPAVGSP--PAPPPPPVPSPPFPC-PADRSPFLPPPPPV 956
++T + +T E S T K +PA +P PAP P P+P P PA +P P P
Sbjct: 446 PTTTKSAPTTPKEPSPTTTK-EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504
Query: 957 TDCSQGSPLPHSPVFP----PPPPEALIPFCSPPDWCLSPPRPA------LSPILPDSPV 1006
+ +P +P P P P+ L P +P +PA L+P P+ P
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564
Query: 1007 SLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMP 1066
P P + P A P PK T P P+ P T T + P
Sbjct: 565 --PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKGTAP 621
Query: 1067 LITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEME 1126
E +P K + T ++ P P K +A +
Sbjct: 622 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP----KGTAPTTPKEPAPTTP 677
Query: 1127 SESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDS 1186
E P + + PT K P +P P+ E +P+TT P S
Sbjct: 678 KEPAPTTPKGTAPTTLKE--------------PAPTTPKKPAPKEL----APTTTKGPTS 719
Query: 1187 SPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKES 1246
+ S KP P + K P +PA E P PTT E + KE
Sbjct: 720 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE----TPPPTTSEVST--PTTTKEP 773
Query: 1247 SAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAEN 1299
+ + P S A SP E VP + + P+ A++
Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSPK--EPGVPTTKTPAATKPEMTTTAKD 824
Score = 49.7 bits (117), Expect = 2e-05
Identities = 95/470 (20%), Positives = 164/470 (34%), Gaps = 77/470 (16%)
Query: 1032 KDTRPPFTNSGQPESSRGSLRPPS-TKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAA 1090
K + P + +P + R SL P S T +ETS T E + G E
Sbjct: 152 KVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKT 211
Query: 1091 QLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDH 1150
++ T ++T L P++ + ++ + + PA T PTP
Sbjct: 212 TSAKETQSIEKTSAKD---LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE---- 264
Query: 1151 GSAAERGGPVSRSPGAP------SAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLV 1204
P S +P P SA P+P+TT ++P P +K+P
Sbjct: 265 --------PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP----- 311
Query: 1205 VPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLE 1264
P K EPA ++ P+PTT + +E ++ + T P
Sbjct: 312 APTTPK----EPAPTTTKE----PAPTTTKSAPTTPKEPAPTTPKKPAP--TTP------ 355
Query: 1265 GGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENS----ADTGGDGESCLSQQDGAAGV 1320
P+ P PAP +EPA + A T + + ++ A
Sbjct: 356 ------KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409
Query: 1321 PETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRN 1380
P+ A ++ E ++ T S P TT++ A +K ++ ++
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTT-TKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKE 466
Query: 1381 HSPSPPVTP---TGAAPSLASPKQVGSIQ------RSIRKSSTSSDNFKALLLKKGSRSD 1431
+P+ P P T P+ +PK+ + +K + ++ A K +
Sbjct: 467 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 526
Query: 1432 TSARMSAA--EMLKNTDPR----------FQRSRSEPSPDAPESPSSCSP 1469
T +++ E L T P + EP+P PE P+ +P
Sbjct: 527 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 576
Score = 40.4 bits (93), Expect = 0.014
Identities = 73/400 (18%), Positives = 135/400 (33%), Gaps = 37/400 (9%)
Query: 1103 PVAPQYHLKPSAFLKSRNS----------TNEMESESQPASVTSSLPTPAKSSSQGDHGS 1152
P+ P+ L P++ S T E + ++ S T + +Q +
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 223
Query: 1153 AAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDF 1212
+A+ P S+ P+ P+ T + +P+ P S PK P K
Sbjct: 224 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK--EPTPTTIKSA 281
Query: 1213 AVEPAENVSEALRAV------PSPTTGEEGSVHSRE------AKESSAAQAGSHATHP-- 1258
P E ++ P+PTT +E + + + KE + S T P
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341
Query: 1259 --GTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPA----ENSADTGGDGESCLS 1312
T+ + P+ P PAP +EPA + A T + +
Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 401
Query: 1313 QQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRD 1372
++ A P+ A ++ E ++ T S P TT++ A +K ++
Sbjct: 402 PKEPAPTTPKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKE--PAPTTTKSAPTTPKE 458
Query: 1373 SDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDT 1432
++ +P+ P P P +P + K + K + T
Sbjct: 459 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518
Query: 1433 SARMSAAEMLKNTDPRFQRSRSEPSPD--APESPSSCSPS 1470
+ + +A K P + +P+ AP +P +P+
Sbjct: 519 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 558
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 84.7 bits (208), Expect = 6e-16
Identities = 137/653 (20%), Positives = 212/653 (32%), Gaps = 64/653 (9%)
Query: 664 SLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQ- 722
S++K L P+ + PK + G L T + + + ++P +
Sbjct: 271 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-----TPKEPTPTTPKEPASTTPKEP 325
Query: 723 SPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGY 782
+P + P P+ + +T + + P T + + E
Sbjct: 326 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385
Query: 783 YIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKS 842
T + P P T+ P P + T P+ P + K + K
Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-----KEPTPTTPKEPAPTTKEPAPTTPKE 440
Query: 843 HRVISPSSGYSSQSNTPTALTP---VPVFLKSVSPANGKGKPKPKVPERKSSLISSVSIS 899
+P + P TP P K SP K +P KS+ ++ +
Sbjct: 441 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPA 497
Query: 900 SSSTSLSSSTSTEGSGTMKKLDPAVGSP--PAPPPPPVPSPPFPC-PADRSPFLPPPPPV 956
++T + +T E S T K +PA +P PAP P P+P P PA +P P P
Sbjct: 498 PTTTKSAPTTPKEPSPTTTK-EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556
Query: 957 TDCSQGSPLPHSPVFP----PPPPEALIPFCSPPDWCLSPPRPA------LSPILPDSPV 1006
+ +P +P P P P+ L P +P +PA L+P P+ P
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616
Query: 1007 SLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMP 1066
P P + P A P PK T P P+ P T T + P
Sbjct: 617 --PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKGTAP 673
Query: 1067 LITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEME 1126
E +P K + T ++ P P K +A +
Sbjct: 674 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP----KGTAPTTPKEPAPTTP 729
Query: 1127 SESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDS 1186
E P + + PT K P +P P+ E +P+TT P S
Sbjct: 730 KEPAPTTPKGTAPTTLKE--------------PAPTTPKKPAPKEL----APTTTKGPTS 771
Query: 1187 SPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKES 1246
+ S KP P + K P +PA E P PTT E + KE
Sbjct: 772 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE----TPPPTTSEVST--PTTTKEP 825
Query: 1247 SAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAEN 1299
+ + P S A SP E VP + + P+ A++
Sbjct: 826 TTIHKSPDESTPELSAEPTPKALENSPK--EPGVPTTKTPAATKPEMTTTAKD 876
Score = 52.8 bits (125), Expect = 3e-06
Identities = 120/658 (18%), Positives = 210/658 (31%), Gaps = 71/658 (10%)
Query: 843 HRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSS 902
H SP S + + + T +S P N K K K + S+S +
Sbjct: 67 HNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPN---KKKTKKVIESEEITEEHSVSENQ 123
Query: 903 TSLSSSTSTEGSGTMKKLDPAVGSPP----------------APPPPPVPSPPFPCPA-- 944
S SSS+S+ S T++K+ + S P P PP A
Sbjct: 124 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 183
Query: 945 --DRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILP 1002
D F P T +Q + + SP P PRP+L P
Sbjct: 184 GLDNGDFKVTTPD-TSTTQHNKVSTSPKITTAKP--------------INPRPSLPP-NS 227
Query: 1003 DSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPES---SRGSLRPPSTKEE 1059
D+ L + E + + D + T++ + +S + P++K
Sbjct: 228 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 287
Query: 1060 TSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSR 1119
P TT+ + + + E A + + AP +P+
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 347
Query: 1120 NSTNEME----SESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPS--AGEAE 1173
T E + +PA T P P + + + P +P P A
Sbjct: 348 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 407
Query: 1174 ARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPP----PQKDFAVEPAENVSEALRAVPS 1229
P+P+T P + ++P P +K+P P P+K P E + P+
Sbjct: 408 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE-PA 466
Query: 1230 PTTGEEGS-VHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVS 1288
PTT +E S +E ++ A + P + + PS P
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526
Query: 1289 PAP-KQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTP 1347
PAP ++PA + ++ A P+ A ++ + ++
Sbjct: 527 PAPTTPKKPAPT------------TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 574
Query: 1348 SRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQR 1407
+ P T + L + + +P+ P PT P +P +
Sbjct: 575 TAPTTPKKLTPTTPEKLAPTTPEKPAPTT-PEELAPTTPEEPTPTTPEEPAPTTPKAAAP 633
Query: 1408 SIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPSPDAPESPS 1465
+ K + + + T+ + +A K T P + EP+P P+ P+
Sbjct: 634 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP---TTLKEPAPTTPKKPA 688
Score = 49.7 bits (117), Expect = 2e-05
Identities = 95/470 (20%), Positives = 164/470 (34%), Gaps = 77/470 (16%)
Query: 1032 KDTRPPFTNSGQPESSRGSLRPPS-TKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAA 1090
K + P + +P + R SL P S T +ETS T E + G E
Sbjct: 204 KVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKT 263
Query: 1091 QLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDH 1150
++ T ++T L P++ + ++ + + PA T PTP
Sbjct: 264 TSAKETQSIEKTSAKD---LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE---- 316
Query: 1151 GSAAERGGPVSRSPGAP------SAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLV 1204
P S +P P SA P+P+TT ++P P +K+P
Sbjct: 317 --------PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP----- 363
Query: 1205 VPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLE 1264
P K EPA ++ P+PTT + +E ++ + T P
Sbjct: 364 APTTPK----EPAPTTTKE----PAPTTTKSAPTTPKEPAPTTPKKPAP--TTP------ 407
Query: 1265 GGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENS----ADTGGDGESCLSQQDGAAGV 1320
P+ P PAP +EPA + A T + + ++ A
Sbjct: 408 ------KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461
Query: 1321 PETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRN 1380
P+ A ++ E ++ T S P TT++ A +K ++ ++
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTT-TKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKE 518
Query: 1381 HSPSPPVTP---TGAAPSLASPKQVGSIQ------RSIRKSSTSSDNFKALLLKKGSRSD 1431
+P+ P P T P+ +PK+ + +K + ++ A K +
Sbjct: 519 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 578
Query: 1432 TSARMSAA--EMLKNTDPR----------FQRSRSEPSPDAPESPSSCSP 1469
T +++ E L T P + EP+P PE P+ +P
Sbjct: 579 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 628
Score = 37.7 bits (86), Expect = 0.090
Identities = 84/446 (18%), Positives = 148/446 (33%), Gaps = 75/446 (16%)
Query: 1034 TRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLS 1093
T PP + P S + K T R P P + ++++ + + Q S
Sbjct: 70 TSPPSSKKAPPPSGASQ----TIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQES 125
Query: 1094 ERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSA 1153
++ + + +R +++ + + T PTP K + GS
Sbjct: 126 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP-KPPVVDEAGSG 184
Query: 1154 AERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFA 1213
+ G +P + + SP T PI+ +P L PP D +
Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAK---------PINPRPSL-----PPNSDTS 230
Query: 1214 VEPAENVSE--ALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSM 1271
E + V++ + + TT ++ S +E K +SA + T +E +A +
Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKE-KTTSAKE---------TQSIEKTSAKDL 280
Query: 1272 SP-SRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSS 1330
+P S+V A P PK E + A T + + ++ A+ P+ +
Sbjct: 281 APTSKVLAK---------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 331
Query: 1331 EACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVT-- 1388
A KE T S P T ++ P+P T
Sbjct: 332 SAPTTPKEPA--PTTTKSAPTTPKE---------------------------PAPTTTKE 362
Query: 1389 PTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTS---ARMSAAEMLKNT 1445
P P +P + KS+ ++ A K T A + E T
Sbjct: 363 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422
Query: 1446 DPRFQRSRSEPSPDAPESPSSCSPSK 1471
+ EP+P P+ P+ +P K
Sbjct: 423 PKEPAPTTKEPAPTTPKEPAPTAPKK 448
Score = 32.3 bits (72), Expect = 3.8
Identities = 56/290 (19%), Positives = 99/290 (34%), Gaps = 36/290 (12%)
Query: 1184 PDSSPSRK--PPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSR 1241
P S PS K PPP + K N + + + S EE SV
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKRSPKP------PNKKKTKKVIESEEITEEHSVSEN 122
Query: 1242 EAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSA 1301
+ SS++ + S +T + AA ++ + + + K+ P
Sbjct: 123 QESSSSSSSSSSSSTIRKIKSSKNSAANR----ELQKKLKVKDNKKNRTKKKPTPKPPVV 178
Query: 1302 DTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIH 1361
D G G L D P+T+ + + PS P ++
Sbjct: 179 DEAGSG---LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT------ 229
Query: 1362 RSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKA 1421
SK L ++ + + T T S K+ SI+++ K +
Sbjct: 230 -SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK--- 285
Query: 1422 LLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPSPDAPESPSSCSPSK 1471
+L K +++T+ + A T P+ EP+P P+ P+S +P +
Sbjct: 286 VLAKPTPKAETTTKGPAL-----TTPK------EPTPTTPKEPASTTPKE 324
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 84.7 bits (208), Expect = 6e-16
Identities = 137/653 (20%), Positives = 212/653 (32%), Gaps = 64/653 (9%)
Query: 664 SLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQ- 722
S++K L P+ + PK + G L T + + + ++P +
Sbjct: 312 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-----TPKEPTPTTPKEPASTTPKEP 366
Query: 723 SPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGY 782
+P + P P+ + +T + + P T + + E
Sbjct: 367 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426
Query: 783 YIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKS 842
T + P P T+ P P + T P+ P + K + K
Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-----KEPTPTTPKEPAPTTKEPAPTTPKE 481
Query: 843 HRVISPSSGYSSQSNTPTALTP---VPVFLKSVSPANGKGKPKPKVPERKSSLISSVSIS 899
+P + P TP P K SP K +P KS+ ++ +
Sbjct: 482 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPA 538
Query: 900 SSSTSLSSSTSTEGSGTMKKLDPAVGSP--PAPPPPPVPSPPFPC-PADRSPFLPPPPPV 956
++T + +T E S T K +PA +P PAP P P+P P PA +P P P
Sbjct: 539 PTTTKSAPTTPKEPSPTTTK-EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597
Query: 957 TDCSQGSPLPHSPVFP----PPPPEALIPFCSPPDWCLSPPRPA------LSPILPDSPV 1006
+ +P +P P P P+ L P +P +PA L+P P+ P
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657
Query: 1007 SLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMP 1066
P P + P A P PK T P P+ P T T + P
Sbjct: 658 --PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKGTAP 714
Query: 1067 LITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEME 1126
E +P K + T ++ P P K +A +
Sbjct: 715 TTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP----KGTAPTTPKEPAPTTP 770
Query: 1127 SESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDS 1186
E P + + PT K P +P P+ E +P+TT P S
Sbjct: 771 KEPAPTTPKGTAPTTLKE--------------PAPTTPKKPAPKEL----APTTTKGPTS 812
Query: 1187 SPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKES 1246
+ S KP P + K P +PA E P PTT E + KE
Sbjct: 813 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE----TPPPTTSEVST--PTTTKEP 866
Query: 1247 SAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAEN 1299
+ + P S A SP E VP + + P+ A++
Sbjct: 867 TTIHKSPDESTPELSAEPTPKALENSPK--EPGVPTTKTPAATKPEMTTTAKD 917
Score = 52.8 bits (125), Expect = 3e-06
Identities = 120/658 (18%), Positives = 210/658 (31%), Gaps = 71/658 (10%)
Query: 843 HRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSS 902
H SP S + + + T +S P N K K K + S+S +
Sbjct: 108 HNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPN---KKKTKKVIESEEITEEHSVSENQ 164
Query: 903 TSLSSSTSTEGSGTMKKLDPAVGSPP----------------APPPPPVPSPPFPCPA-- 944
S SSS+S+ S T++K+ + S P P PP A
Sbjct: 165 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 224
Query: 945 --DRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILP 1002
D F P T +Q + + SP P PRP+L P
Sbjct: 225 GLDNGDFKVTTPD-TSTTQHNKVSTSPKITTAKP--------------INPRPSLPP-NS 268
Query: 1003 DSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPES---SRGSLRPPSTKEE 1059
D+ L + E + + D + T++ + +S + P++K
Sbjct: 269 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 328
Query: 1060 TSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSR 1119
P TT+ + + + E A + + AP +P+
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 388
Query: 1120 NSTNEME----SESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPS--AGEAE 1173
T E + +PA T P P + + + P +P P A
Sbjct: 389 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 448
Query: 1174 ARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPP----PQKDFAVEPAENVSEALRAVPS 1229
P+P+T P + ++P P +K+P P P+K P E + P+
Sbjct: 449 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE-PA 507
Query: 1230 PTTGEEGS-VHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVS 1288
PTT +E S +E ++ A + P + + PS P
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567
Query: 1289 PAP-KQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTP 1347
PAP ++PA + ++ A P+ A ++ + ++
Sbjct: 568 PAPTTPKKPAPT------------TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 615
Query: 1348 SRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQR 1407
+ P T + L + + +P+ P PT P +P +
Sbjct: 616 TAPTTPKKLTPTTPEKLAPTTPEKPAPTT-PEELAPTTPEEPTPTTPEEPAPTTPKAAAP 674
Query: 1408 SIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPSPDAPESPS 1465
+ K + + + T+ + +A K T P + EP+P P+ P+
Sbjct: 675 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP---TTLKEPAPTTPKKPA 729
Score = 49.7 bits (117), Expect = 2e-05
Identities = 95/470 (20%), Positives = 164/470 (34%), Gaps = 77/470 (16%)
Query: 1032 KDTRPPFTNSGQPESSRGSLRPPS-TKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAA 1090
K + P + +P + R SL P S T +ETS T E + G E
Sbjct: 245 KVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKT 304
Query: 1091 QLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDH 1150
++ T ++T L P++ + ++ + + PA T PTP
Sbjct: 305 TSAKETQSIEKTSAKD---LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE---- 357
Query: 1151 GSAAERGGPVSRSPGAP------SAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLV 1204
P S +P P SA P+P+TT ++P P +K+P
Sbjct: 358 --------PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP----- 404
Query: 1205 VPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLE 1264
P K EPA ++ P+PTT + +E ++ + T P
Sbjct: 405 APTTPK----EPAPTTTKE----PAPTTTKSAPTTPKEPAPTTPKKPAP--TTP------ 448
Query: 1265 GGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENS----ADTGGDGESCLSQQDGAAGV 1320
P+ P PAP +EPA + A T + + ++ A
Sbjct: 449 ------KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502
Query: 1321 PETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRN 1380
P+ A ++ E ++ T S P TT++ A +K ++ ++
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTT-TKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKE 559
Query: 1381 HSPSPPVTP---TGAAPSLASPKQVGSIQ------RSIRKSSTSSDNFKALLLKKGSRSD 1431
+P+ P P T P+ +PK+ + +K + ++ A K +
Sbjct: 560 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 619
Query: 1432 TSARMSAA--EMLKNTDPR----------FQRSRSEPSPDAPESPSSCSP 1469
T +++ E L T P + EP+P PE P+ +P
Sbjct: 620 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP 669
Score = 37.7 bits (86), Expect = 0.090
Identities = 84/446 (18%), Positives = 148/446 (33%), Gaps = 75/446 (16%)
Query: 1034 TRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLS 1093
T PP + P S + K T R P P + ++++ + + Q S
Sbjct: 111 TSPPSSKKAPPPSGASQ----TIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQES 166
Query: 1094 ERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSA 1153
++ + + +R +++ + + T PTP K + GS
Sbjct: 167 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP-KPPVVDEAGSG 225
Query: 1154 AERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFA 1213
+ G +P + + SP T PI+ +P L PP D +
Sbjct: 226 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAK---------PINPRPSL-----PPNSDTS 271
Query: 1214 VEPAENVSE--ALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSM 1271
E + V++ + + TT ++ S +E K +SA + T +E +A +
Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKE-KTTSAKE---------TQSIEKTSAKDL 321
Query: 1272 SP-SRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSS 1330
+P S+V A P PK E + A T + + ++ A+ P+ +
Sbjct: 322 APTSKVLAK---------PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK 372
Query: 1331 EACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVT-- 1388
A KE T S P T ++ P+P T
Sbjct: 373 SAPTTPKEPA--PTTTKSAPTTPKE---------------------------PAPTTTKE 403
Query: 1389 PTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTS---ARMSAAEMLKNT 1445
P P +P + KS+ ++ A K T A + E T
Sbjct: 404 PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463
Query: 1446 DPRFQRSRSEPSPDAPESPSSCSPSK 1471
+ EP+P P+ P+ +P K
Sbjct: 464 PKEPAPTTKEPAPTTPKEPAPTAPKK 489
Score = 32.3 bits (72), Expect = 3.8
Identities = 56/290 (19%), Positives = 99/290 (34%), Gaps = 36/290 (12%)
Query: 1184 PDSSPSRK--PPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSR 1241
P S PS K PPP + K N + + + S EE SV
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKP------PNKKKTKKVIESEEITEEHSVSEN 163
Query: 1242 EAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSA 1301
+ SS++ + S +T + AA ++ + + + K+ P
Sbjct: 164 QESSSSSSSSSSSSTIRKIKSSKNSAANR----ELQKKLKVKDNKKNRTKKKPTPKPPVV 219
Query: 1302 DTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIH 1361
D G G L D P+T+ + + PS P ++
Sbjct: 220 DEAGSG---LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT------ 270
Query: 1362 RSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKA 1421
SK L ++ + + T T S K+ SI+++ K +
Sbjct: 271 -SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK--- 326
Query: 1422 LLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPSPDAPESPSSCSPSK 1471
+L K +++T+ + A T P+ EP+P P+ P+S +P +
Sbjct: 327 VLAKPTPKAETTTKGPAL-----TTPK------EPTPTTPKEPASTTPKE 365
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 83.6 bits (205), Expect = 1e-15
Identities = 74/213 (34%), Positives = 96/213 (45%), Gaps = 51/213 (23%)
Query: 913 GSGTMKKLDPAVGSPPAPPP-PPVPSPPFPCPADRSP------------FLPPPPPVTDC 959
GSG +V SP PPP PP+ SPP P P P PPPPPV
Sbjct: 283 GSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFG 342
Query: 960 SQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALS-PILPDSPVSLP---LPPPLL 1015
S G+P P SP PP P+ F +PP PP PA P LP P+S P PPP
Sbjct: 343 SPGTPPPPSPPSFPPHPD----FAAPPP---PPPPPAADYPTLPPPPLSQPTGGAPPP-- 393
Query: 1016 PSSEPPPAPPLDPKFMKDTRPPFTNS-GQPESSRGSLRPP---STKEETSRPPMPLITTE 1071
P PPP PP PPFT + GQP ++ PP +TK ++S P + ++
Sbjct: 394 PPPPPPPGPP---------PPPFTGADGQP-----AIPPPLSDTTKPKSSLPAVSDARSD 439
Query: 1072 ALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPV 1104
L ++ G + ++ E+ QE+R V
Sbjct: 440 LLSAIR-------QGFQLRRVEEQREQEKRDVV 465
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 83.2 bits (204), Expect = 2e-15
Identities = 153/690 (22%), Positives = 239/690 (34%), Gaps = 102/690 (14%)
Query: 736 SRSQSTVSAGSSMTSAT-----TPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQ 790
+RS T S G+SM ++T TP TP S +S S P T
Sbjct: 1727 ARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS--ATPIDTSTPVTTST 1784
Query: 791 EDPGNPAGGCSTS--------SGVPTGNGPVRH--VQEGSRATMPQVPGGSVKPKIMSPE 840
E +P TS P + PV H V +T+ P S P + S
Sbjct: 1785 EATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTA 1844
Query: 841 KSHRVISPSSGYSSQSNTP----TALTPVPVFLKSV------------------------ 872
S +P+ G S ++TP TALT +PV +V
Sbjct: 1845 VSSSP-TPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQ 1903
Query: 873 ---SPANGKGKPKPKVPERK------SSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPA 923
SP G P R+ S +S+ +++SS + S+T + + A
Sbjct: 1904 VSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQA 1963
Query: 924 VGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFC 983
SP +P+P + + +P + S+ S L +PV P
Sbjct: 1964 SSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGS 2023
Query: 984 SPPDWCLSPPRPALSPILPDSPVS-LPLPPPLLPSSE--PPPAPPLDPKFMKDTRPPFTN 1040
S P +P +P++ +P+ L+ SSE P+D K ++
Sbjct: 2024 SSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASS 2083
Query: 1041 SGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQ 1100
S E S ++ PS PL+T+ L + + EA+ LS T +
Sbjct: 2084 SATAEGSSMTISAPSEGS-------PLLTSIPLSTTPV------ASPEASTLS-TTPVDS 2129
Query: 1101 RTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPV 1160
+PV + S E S S S TP S A+ +
Sbjct: 2130 NSPVITSTEVSSSPI--------PTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTL 2181
Query: 1161 SRSP---GAPSAGEAEARPSPST---TPLPDSSPSRKPPPISKKP-KLFLVVPPPQKDFA 1213
S +P P EAR SP+T T +P S+PS P + P VV +
Sbjct: 2182 STTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLS 2241
Query: 1214 VEPAEN---VSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGS 1270
P + V+ + A SPTT E S+ + E + +H +++ +
Sbjct: 2242 ATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSH---TLVANSEVST 2298
Query: 1271 MSPSRVEANVPM-VQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSS 1329
+S + V++N P + S P E T +G + L++ V T A
Sbjct: 2299 LSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMP----VSTTMVASFE 2354
Query: 1330 SEACDFLKEDGNDEVMTPSR----PRTTED 1355
+ D + V T S+ P T +D
Sbjct: 2355 TSTLSTTPADTSTPVTTYSQAGSSPTTADD 2384
Score = 82.0 bits (201), Expect = 4e-15
Identities = 170/752 (22%), Positives = 269/752 (35%), Gaps = 121/752 (16%)
Query: 715 KSGSSPSQS-----PCSDLEEPWLPRSR---SQSTVSAGSSMTSATTPNVYSLCGATPSQ 766
++GSSP+ + P S E P + S V + + T +TTP S T ++
Sbjct: 2374 QAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTE 2433
Query: 767 SDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMP- 825
+ +S +E G P+ G + + +P PV + G+ +T P
Sbjct: 2434 ASSSPTTAE------------GTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPV 2481
Query: 826 --QVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKP 883
P + SP + ++ P S S S T LT +PV V+
Sbjct: 2482 DTSTPMTTSTEASSSPTTAEDIVVPISTASEGS---TLLTSIPVSTTPVASPEASTLSTT 2538
Query: 884 KV----PERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPP 939
V P S+ ISS + S+ TS+ +ST +EGS ++ + PV + P
Sbjct: 2539 PVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSM-------------PVSTKP 2585
Query: 940 FPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSP 999
S+ S L +PV P S P P +P
Sbjct: 2586 LA-----------------SSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTP 2628
Query: 1000 I-LPDSPVSLPLPPPLLPSSEPP--PAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPST 1056
+ S S+ + + SSE P+D + + T S P ++ GS P ST
Sbjct: 2629 SEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTST--GTSSSPTTAEGSSMPTST 2686
Query: 1057 KEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFL 1116
E S P ++ + L + +EA+ LS T + TPV +
Sbjct: 2687 PGERSTPLTNILVSTTLL----------ANSEASTLS-TTPVDTSTPV--------TTSA 2727
Query: 1117 KSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRS---PGAPSAGEAE 1173
++ +S E S S S TP S A+ VS + P E
Sbjct: 2728 EASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTE 2787
Query: 1174 ARPSPST---TPLPDSSPSRKPPPISKKPKLFLVVPPPQ----KDFAVEPAENVSEALRA 1226
A SP+T T +P S+PS P++ P V + V+ + V+ + +A
Sbjct: 2788 ASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKA 2847
Query: 1227 VPSPTTGE----------EGSVHSREAKESSAAQAGSHATHPGTSVLE------GGAAGS 1270
SPTT E EGS S+ A S A+ T+ ++ GS
Sbjct: 2848 SSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGS 2907
Query: 1271 MSPSRVE-ANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSS 1329
SP+ E ++P+ P P ++ G S LS P T +A +S
Sbjct: 2908 SSPTTAEGTSMPISTPSEVSTP-LTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEAS 2966
Query: 1330 SEACDFLKEDGNDEVMTPSRPRTTEDLFAA----IHRSKRKVLGRRDSDDD---HSRNHS 1382
S E + + TP RT + + S+ L R +D + +
Sbjct: 2967 SSPT--TAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEA 3024
Query: 1383 PSPPVTPTGAAPSLASPKQVGSIQRSIRKSST 1414
S P T G +++P + + SI S+T
Sbjct: 3025 SSSPTTAEGTGIPISTPSEGSTPLTSIPVSTT 3056
Score = 75.5 bits (184), Expect = 4e-13
Identities = 172/760 (22%), Positives = 275/760 (36%), Gaps = 117/760 (15%)
Query: 675 PSRTDSLRRIPKKSSQCNG----QVLNESLIATLQHSLQLSLPGKSGSSPSQSPCSDLEE 730
P + S+ +P SS+ + V + + T + S + S P+ +P S+
Sbjct: 512 PLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTP-SEGST 570
Query: 731 PWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTD-PWGYYID---- 785
P S V + + T++TTP + T S++ +SS +E T P Y +
Sbjct: 571 PLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTT 630
Query: 786 YTGMQEDPGNPAGG-CSTSSGVPT-GNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSH 843
T M A ST S P N PV E + ++ G+ P E S
Sbjct: 631 ITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSST--TAEGTSMPTSTYTEGST 688
Query: 844 RVIS--------PSSGYSSQSNTPT-ALTPVPVFLK-SVSPANGKGKPKP-KVPERKSSL 892
+ S SS S+ S TP TPV + S SP G P P S+
Sbjct: 689 PLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTP 748
Query: 893 ISSVSISSS--STSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFL 950
++S+ +S + ++S +S+ ST T + + + +P S P P++ SP L
Sbjct: 749 LTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLL 808
Query: 951 PPPP----PVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPV 1006
P PVT P + P ++ P + + S P PA +P S
Sbjct: 809 TSIPVSITPVTS-------PEASTLSTTPVDSNSPVTTSTE-VSSSPTPAEGTSMPTSTY 860
Query: 1007 SLPLPP----PLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQ----PESSRGSLRPPSTKE 1058
S P P+ + A DT P TNS + P +S G+ P ST
Sbjct: 861 SEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPG 920
Query: 1059 ETSRP-------PMPLITTEALQMVQLRPVRKNSG-------------AEAAQLSERTAQ 1098
E S P P++++EA + + PV ++ AE + T
Sbjct: 921 EGSTPLTSMPDSTTPVVSSEA-RTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPS 979
Query: 1099 EQRTPVA--PQYHLKPSAFLKSRNSTNEMESESQ-PASVTSSLPTPAKSSSQGDHGSAAE 1155
E TP+ P H + S ST ++S + S +S P P + + +E
Sbjct: 980 EGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSE 1039
Query: 1156 RGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSP------------------------SRK 1191
P++R P + + + + STTP S+P S
Sbjct: 1040 GSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEG 1099
Query: 1192 PPPISKKP-KLFLVVPPPQKDFAVEPAEN---VSEALRAVPSPTTGEEGSVHSREAKESS 1247
P++ P LVV + P + V+ + A SPTT E S+ + E +
Sbjct: 1100 STPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGT 1159
Query: 1248 --------------AAQAGSHATHP---GTSVLEGGAAGSMSPSRVEANVPMVQPDVSPA 1290
+++A + +T P T V A S P+ ++P P
Sbjct: 1160 TPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERST 1219
Query: 1291 PKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSS 1330
P P ++ + S LS P T +A +SS
Sbjct: 1220 PLTSMPVRHTPVASSEA-STLSTSPVDTSTPVTTSAETSS 1258
Score = 72.4 bits (176), Expect = 3e-12
Identities = 152/680 (22%), Positives = 238/680 (35%), Gaps = 94/680 (13%)
Query: 685 PKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSA 744
P+ S+ V + S + T +P + G+S S SD P S + V++
Sbjct: 2117 PEASTLSTTPVDSNSPVITSTEVSSSPIPTE-GTSMQTSTYSDRRTPLTSMPVSTTVVAS 2175
Query: 745 GSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSS 804
+ T +TTP + +TP + T + S T G P+ G + +
Sbjct: 2176 SAISTLSTTP----VDTSTPVTNSTEARSSPTTS--------EGTSMPTSTPSEGSTPFT 2223
Query: 805 GVPTGNGPVRHVQEGSRATMP---QVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTA 861
+P PV + + + P P + SP + P+S S+ TP
Sbjct: 2224 SMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTL-SEGTTPLT 2282
Query: 862 LTPVPVFLKSVSPAN--GKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKK 919
PV L + S + P S+ SS ++ TS+ +STS+EG+ + +
Sbjct: 2283 SIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTR 2342
Query: 920 L-----------DPAVGSPPAPPPPPV----PSPPFPCPADRSPFLPPPPPVTDCSQGS- 963
+ + + PA PV + P AD + P + S+GS
Sbjct: 2343 MPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSM-----PTSTYSEGST 2397
Query: 964 PLPHSPV--FPPPPPEALIPFCSPPDW---------CLSPPRPALSPILPDSP------- 1005
PL PV P EA +P D S P A +P SP
Sbjct: 2398 PLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP 2457
Query: 1006 -VSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPP 1064
S+P+ + SSE DT P T S + SS P+T E+
Sbjct: 2458 LASMPVSTTPVVSSEAGTLSTTP----VDTSTPMTTSTEASSS------PTTAEDI---V 2504
Query: 1065 MPLIT-TEALQMVQLRPVRKN--SGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNS 1121
+P+ T +E ++ PV + EA+ LS T + +PV + SA
Sbjct: 2505 VPISTASEGSTLLTSIPVSTTPVASPEASTLS-TTPVDSNSPVVTSTEISSSA------- 2556
Query: 1122 TNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSP---GAPSAGEAEARPSP 1178
E S P S S TP +S A+ +S +P P E SP
Sbjct: 2557 -TSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSP 2615
Query: 1179 STTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSV 1238
TT S P P +S LV P R + + +TG S
Sbjct: 2616 -TTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSP 2674
Query: 1239 HSREAKESSAAQAGSHATH-----PGTSVLEGGAAGSMSPSRVEANVPM-VQPDVSPAPK 1292
+ E + G +T T++L A ++S + V+ + P+ + S +P
Sbjct: 2675 TTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPT 2734
Query: 1293 QEEPAENSADTGGDGESCLS 1312
E T DG + L+
Sbjct: 2735 TAEGTSMRISTPSDGSTPLT 2754
Score = 65.5 bits (158), Expect = 4e-10
Identities = 235/1249 (18%), Positives = 410/1249 (32%), Gaps = 194/1249 (15%)
Query: 403 SPHATYSTSIIPNATLSSSSEVIAIPTAQSAGQRESKSSGSSHARIKSRDHLISRHAVKG 462
SP TSI + S+ + ++P + + S++S S + S+ + +
Sbjct: 433 SPTTAEDTSIATSTPSEGSTPLTSMPVSTTP-VASSEASNLSTTPVDSKTQVTTSTEASS 491
Query: 463 DPQSPGRHWNEGHATILSQDLDPHSPGEPALLSLCDSAVPLNAPANRENGSQAMPYNCRN 522
P + A + S S G L S+ S +P+ ++ + P +
Sbjct: 492 SPPT---------AEVNSMPTSTPSEGSTPLTSMSVSTMPV--ASSEASTLSTTPVDTST 540
Query: 523 NLAFPAHPQDVDGKSESSYSGGGGHSSSEPWEYKSSGNGRAS--PLKPHLATPGYSTPTS 580
V SE+S S +S P S G+ + P+ L ++ TS
Sbjct: 541 ---------PVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTS 591
Query: 581 NMSSCSLD-QTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGNLCNSSDGFGNPRHSVINV 639
+ S T++ E + S + + S +++ G ++ S+ + S ++
Sbjct: 592 TTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLST 651
Query: 640 FVGRAQKNQGDRSNYQDKSLSRNISLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNES 699
D + S S A+ +P S T + P S N ++ S
Sbjct: 652 -------TPVDSNTPVTTSTEATSSSTTAEGTSMPTS-TYTEGSTPLTSMPVNTTLVASS 703
Query: 700 LIATLQHS-LQLSLPGKSGSSPSQSPC------------SDLEEPWLPRSRSQSTVSAGS 746
+TL + + S P + + S SP S+ P S++ +++
Sbjct: 704 EASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSE 763
Query: 747 SMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGV 806
+ T +TTP S T +++ S +E G P+ G + +
Sbjct: 764 ASTLSTTPLDTSTHITTSTEASCSPTTTE------------GTSMPISTPSEGSPLLTSI 811
Query: 807 PTGNGPVRHVQEGSRATMPQVPGGSVKPKI---MSPEKSHRVISPSSGYSSQSNTPTALT 863
P PV + + +T P V SP + P+S YS + TP
Sbjct: 812 PVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYS-EGRTPLTSM 870
Query: 864 PVPVFLKSVSPANGKGKPK--PKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLD 921
PV L + S + P S+ S +S TS+ +ST EGS + +
Sbjct: 871 PVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMP 930
Query: 922 -----------------PAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDC----- 959
P S P S P P P T
Sbjct: 931 DSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPV 990
Query: 960 -------SQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVS-LPLP 1011
S+ S L +PV P SPP P +P +P++ +P+
Sbjct: 991 SHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVS 1050
Query: 1012 PPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSR----GSLRPPSTKEETSRP---- 1063
++ SSE DT P T Q SS G+ P ST E S P
Sbjct: 1051 TTMVASSETSTLSTTPA----DTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSV 1106
Query: 1064 --PMPLITTEALQMVQLRPVRKN-------------SGAEAAQLSERTAQEQRTPVAPQY 1108
L+ + + PV + + AE + E TP+A
Sbjct: 1107 PVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMP 1166
Query: 1109 HLKPSAFLKSRN--STNEMESESQPASVT-SSLPTPAKSSSQGDHGSAAERGGPVSRSPG 1165
N ST ++S++Q A+ T +S P P + + ER P++ P
Sbjct: 1167 VSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPV 1226
Query: 1166 APSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALR 1225
+ + + ST+P+ S+P V+ +
Sbjct: 1227 RHTPVASSEASTLSTSPVDTSTP-------------------------------VTTSAE 1255
Query: 1226 AVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMV-Q 1284
SPTT E S+ + E S + T+++ A ++ + V+ P+V
Sbjct: 1256 TSSSPTTAEGTSLPTSTTSEGSTLLTSIPVS---TTLVTSPEASTLLTTPVDTKGPVVTS 1312
Query: 1285 PDVSPAPKQEEPAENSADTGGDGESCLSQQD--------------GAAGVPETNAAGSSS 1330
+VS +P E T +G + L+ V + +S+
Sbjct: 1313 NEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTST 1372
Query: 1331 EACD--------FLKEDGNDEVMTP--SRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRN 1380
EAC + E TP S P +T + ++ S S +
Sbjct: 1373 EACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSS-EASTLSATPVDTSTPGTTSA 1431
Query: 1381 HSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAE 1440
+ S P T G + ++P + + +SI S+T N +A L S +++
Sbjct: 1432 EATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTA 1491
Query: 1441 MLKNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRS 1500
+ + P S + +P + + P + P S Y ++
Sbjct: 1492 VSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQA 1551
Query: 1501 RTPPSAA------SSRYS-----MRNRIQSSPMTVISEGEGEAVEPVDS 1538
+ P+ A +S YS + + S+ + V SE + P+DS
Sbjct: 1552 SSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDS 1600
Score = 65.1 bits (157), Expect = 5e-10
Identities = 152/677 (22%), Positives = 263/677 (38%), Gaps = 100/677 (14%)
Query: 647 NQGDRSNYQDKSLSRNISLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQH 706
+QGD N Q + LS+++ A + T+ + P+ C+ + +++
Sbjct: 43 SQGDVLNRQCQQLSQHVRTGSAANTATGTTSTNVVE--PRMYLSCS----TNPEMTSIES 96
Query: 707 SLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTV---SAGSSMTSATTPNVYSLCGAT 763
S+ PG S + + + E S S ST S+ +S TTP + +T
Sbjct: 97 SVTSDTPGVSSTRMTPTESRTTSE-----STSDSTTLFPSSTEDTSSPTTPEGTDVPMST 151
Query: 764 PSQSDTSSVKSEY-TDPWGYYIDYTGM--QEDPGNPAGGCSTSSGVPTGNG----PVRHV 816
PS+ SS + T P + YT + + D P + +S PT P
Sbjct: 152 PSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTN 211
Query: 817 QEGSRATMPQVPGGSVKPKIMSPEKSHRVISP---SSGYSSQSNTPTALTPVPVFLKSVS 873
EGS + +P ++K + S E + +P S+ + + ++ T S S
Sbjct: 212 SEGS-TPLTSMPASTMK--VASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNS 268
Query: 874 PANGKGKPKPKVPERKSSLISS----VSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPA 929
+G P ++P ++SS +S + ++T++ TSTE S + P +
Sbjct: 269 APSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSS-----PTTAEGTS 323
Query: 930 PPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWC 989
P P + + +P +P+ S + + +P +
Sbjct: 324 IPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSM 383
Query: 990 LSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAP--PLDPKFMKDTRPPFTNSGQPESS 1047
L+ S L + PVS L + SSE P+D K T ++S P ++
Sbjct: 384 LTSTLSEGSTPLTNMPVSTIL----VASSEASTTSTIPVDSKTFVTTASEASSS--PTTA 437
Query: 1048 RGSLRPPSTKEETSRP--PMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVA 1105
+ ST E S P MP+ TT PV + +EA+ LS TPV
Sbjct: 438 EDTSIATSTPSEGSTPLTSMPVSTT---------PV---ASSEASNLST-------TPVD 478
Query: 1106 PQYHLKPSAFLKSRNSTNEMESESQPASVTSSLP--------TPAKSSSQGDHGSAAERG 1157
K++ +T+ S S P + +S+P TP S S A+
Sbjct: 479 S----------KTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEA 528
Query: 1158 GPVSRSP---GAPSAGEAEARPS---PSTTPLPDSSPSRKPPPISKKP-KLFLVVPPPQK 1210
+S +P P +EA S P T +P S+PS P++ P LVV
Sbjct: 529 STLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEAS 588
Query: 1211 DFAVEPAEN---VSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHAT--HPGTSVLEG 1265
+ PA++ V+ + A S TT E S+ + S+ ++ G+ T T+++
Sbjct: 589 TTSTTPADSNTFVTTSSEASSSSTTAEGTSMPT-----STYSERGTTITSMSVSTTLVAS 643
Query: 1266 GAAGSMSPSRVEANVPM 1282
A ++S + V++N P+
Sbjct: 644 SEASTLSTTPVDSNTPV 660
Score = 62.0 bits (149), Expect = 4e-09
Identities = 161/789 (20%), Positives = 269/789 (34%), Gaps = 125/789 (15%)
Query: 675 PSRTDSLRRIPKKSSQCNGQVLNESLIATLQHS-LQLSLPGKSGSSPSQSPC-------- 725
P+ T R P + + +L S +TL + + S P + + S SP
Sbjct: 2683 PTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMR 2742
Query: 726 ----SDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWG 781
SD P S V++ + T +TT S+ T +++ +S +E T
Sbjct: 2743 ISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSM-- 2800
Query: 782 YYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMP---QVPGGSVKPKIMS 838
P+ + + +P + PV + G+ +T P P + S
Sbjct: 2801 ----------PTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSS 2850
Query: 839 PEKSHRVISP----SSGYSSQSNTPTALTPV-----------------PVFLK---SVSP 874
P + ++ P S G + ++ P + TPV PV S SP
Sbjct: 2851 PTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSP 2910
Query: 875 ANGKGKPKP-KVPERKSSLISSVSISSSST--SLSSSTSTEGSGTMKKLDPAVGSPPAPP 931
+G P P S+ ++S+ +S+ S +S+ ST T + + + +P
Sbjct: 2911 TTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPT 2970
Query: 932 PPPVPSPPFPCPADRSPFLPPPPPVT---DCSQGSPLPHSPVFPPPPPEALIPFCSPPDW 988
S P P +R L T S+ S L +P P S P
Sbjct: 2971 TAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTT 3030
Query: 989 CLSPPRPALSPILPDSPV-SLPLP--PPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPE 1045
P +P +P+ S+P+ P +P + P+D T ++S P
Sbjct: 3031 AEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSS--PT 3088
Query: 1046 SSRGSLRPPSTKEETSRP--PMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTP 1103
+ G+ P ST E S P +P+ TT PV + A T + TP
Sbjct: 3089 PAEGTSMPISTYSEGSTPLTGVPVSTT---------PVTSS----AISTLSTTPVDTSTP 3135
Query: 1104 VAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKS---------SSQGDHGSAA 1154
V ++ +S E S P S S TP SS+ SA
Sbjct: 3136 VTTS--------TEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSAT 3187
Query: 1155 ERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDF-- 1212
PV S ++ EA + + T +P S+PS P++ P V +
Sbjct: 3188 ----PVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILS 3243
Query: 1213 --AVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGS 1270
V+ ++ + A SP T E S+ + E S + T+ + +
Sbjct: 3244 TTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVS---TTTVASSETST 3300
Query: 1271 MSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSS 1330
+S + + + P+ + +S+ DG S + P TN + S++
Sbjct: 3301 LSTTPADTSTPVTTYSQA----------SSSPPIADGTSMPTSTYSEGSTPLTNMSFSTT 3350
Query: 1331 EACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPT 1390
+ E T S T D + S L ++ SPS TP
Sbjct: 3351 PVV-------SSEASTLS--TTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPL 3401
Query: 1391 GAAPSLASP 1399
+ P +P
Sbjct: 3402 ASMPVSTTP 3410
Score = 61.6 bits (148), Expect = 6e-09
Identities = 193/872 (22%), Positives = 303/872 (34%), Gaps = 111/872 (12%)
Query: 675 PSRTDSLRRIPKKSSQCNGQVLNESLIATLQHS-LQLSLPGKSGSSPSQSPCSDLEEPWL 733
P+ T S P S + +++ S +TL + + S+P + + S SP + E +
Sbjct: 1092 PTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTT-AEGTSI 1150
Query: 734 PRSRSQSTVSAGSSMTSATTPNVYS---LCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQ 790
P S + +SM +TT V S TP S T S + T M
Sbjct: 1151 PTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSM- 1209
Query: 791 EDPGNPAGGCSTSSGVPTGNGPVRH--VQEGSRATMPQVPGGSVKPKIMSPEKSHRVISP 848
P + G ST P + PVRH V +T+ P + P S E S +
Sbjct: 1210 --PTSTPGERST----PLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTA 1263
Query: 849 ---SSGYSSQSNTPTALTPVPVFL-----------------------------KSVSPAN 876
S S+ S T LT +PV S +PA
Sbjct: 1264 EGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAE 1323
Query: 877 GKGKPKPKVPERKSSL----ISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPP 932
G P E ++ L +++ ++SS+ S+ S+T + S + A SP
Sbjct: 1324 GTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEG 1383
Query: 933 PPVPSPPFPCPADRSPFLPPPPPVTD---CSQGSPLPHSPVFPPPPPEALIPFCSPPDWC 989
+P+ P++ + L P T S+ S L +PV P S P
Sbjct: 1384 TSMPNSN---PSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTA 1440
Query: 990 LSPPRPALSPILPDSPV-SLPLPPPLLPSSEPPP--APPLDPKFMKDTRPPFTNSGQPES 1046
P +P +P+ S+P+ + +SE P+D T ++S P
Sbjct: 1441 EGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE 1500
Query: 1047 ---------SRGSLR----PPSTKEETSRPPMPLITTEALQMVQLRPVRKNSG----AEA 1089
S GS P ST S L TT A+ + + S A+
Sbjct: 1501 GTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADG 1560
Query: 1090 AQLSERTAQEQRTPVA--PQYHLKPSAFLKSRNSTNEMESESQ-PASVTSSLPTPAKSSS 1146
+ T E TP+ P + + + ST ++S++Q AS +S T A+ SS
Sbjct: 1561 TSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSS 1620
Query: 1147 QG----DHGSAAERGGPVSRSPGA-PSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKL 1201
GS PVS +P A P A STTP+ +SP +S P
Sbjct: 1621 MTISTPSEGSPLLTSIPVSTTPVASPEASTL------STTPVDSNSPVITSTEVSSSPTP 1674
Query: 1202 FLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTS 1261
P + S +R +P S S ++S S +
Sbjct: 1675 AEGTSMPTSTYTEGRTPLTSITVRT--TPVASSAISTLSTTPVDNSTPVTTSTEARSSPT 1732
Query: 1262 VLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVP 1321
EG + + +PS E P+ VS P A + T D + ++ A P
Sbjct: 1733 TSEGTSMPNSTPS--EGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSP 1790
Query: 1322 ETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNH 1381
T A G+S + E MTP +T + S+ L D
Sbjct: 1791 -TTAEGTS------IPTSTLSEGMTPL--TSTPVSHTLVANSEASTLSTTPVD------- 1834
Query: 1382 SPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEM 1441
S SP VT T A S +P + SI S +++ + + S+T+ + +
Sbjct: 1835 SNSPVVTST-AVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAV 1893
Query: 1442 LKNTDPRFQRSRSEPSPDAPESPSSCSPSKNR 1473
+ + S P+ S + +P + R
Sbjct: 1894 TSTPVTTYAQVSSSPTTADGSSMPTSTPREGR 1925
Score = 52.8 bits (125), Expect = 3e-06
Identities = 152/766 (19%), Positives = 266/766 (34%), Gaps = 121/766 (15%)
Query: 711 SLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTS 770
S P G+S S S+ P S +TV++ + T +TTP S T SQ+ +S
Sbjct: 3262 SPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSS 3321
Query: 771 SVKSEYTD-PWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMP---Q 826
++ T P Y + G + + + PV + + +T P
Sbjct: 3322 PPIADGTSMPTSTYSE-------------GSTPLTNMSFSTTPVVSSEASTLSTTPVDTS 3368
Query: 827 VPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPV---PVFLKSVSPANGKGKPKP 883
P + +SP + P+S S+ TP A PV PV V+ +
Sbjct: 3369 TPVTTSTEASLSPTTAEGTSIPTSS-PSEGTTPLASMPVSTTPVVSSEVNTLS------- 3420
Query: 884 KVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCP 943
P ++L+++ + +SSS +++ TS S T + GS P P +P
Sbjct: 3421 TTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSE------GSTPLSIMPLSTTP----- 3469
Query: 944 ADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPD 1003
S+ S L +PV P P S P P +
Sbjct: 3470 -------------VASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGS 3516
Query: 1004 SPV-SLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSR 1062
+P+ ++P+ + SSE T P +N+ SS+ S P + + T R
Sbjct: 3517 TPLTNMPVSTTPVASSEASTL---------STTPVDSNTFVTSSSQASSSPATLQVTTMR 3567
Query: 1063 PPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNST 1122
P + +L + L S A + ++ TPV ST
Sbjct: 3568 MSTPSEGSSSLTTMLLSSTYVTS--SEASTPSTPSVDRSTPVT--------------TST 3611
Query: 1123 NEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTP 1182
+ + P +T + TP++ S+ P++ P + ++ + ST P
Sbjct: 3612 QSNSTPTPPEVITLPMSTPSEVST------------PLTIMPVSTTSVTISEAGTASTLP 3659
Query: 1183 LPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPT---TGEEGSVH 1239
+ S+P +S P V P + S L +P T T EGS
Sbjct: 3660 VDTSTPVITSTQVSSSP-----VTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTL 3714
Query: 1240 SREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAEN 1299
S + +S S ++ L+ P + + +P + E +
Sbjct: 3715 STPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTP 3774
Query: 1300 SADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAA 1359
S + S + +G++ T G+++ M+ + R+T L
Sbjct: 3775 SIPSVYTSMSMTTASEGSSS--PTTLEGTTTMP------------MSTTSERST--LLTT 3818
Query: 1360 IHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNF 1419
+ S V+ ++ + S P+ + A S + P +V +I+ SI +S S
Sbjct: 3819 VLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISI--TSERSTPL 3876
Query: 1420 KALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPSPDAPESPS 1465
LL+ S T + +T P + PS D +P+
Sbjct: 3877 TTLLV-----STTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPT 3917
Score = 40.0 bits (92), Expect = 0.018
Identities = 109/535 (20%), Positives = 188/535 (35%), Gaps = 66/535 (12%)
Query: 749 TSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPT 808
+ A+TP+ S+ +TP + T S S T P + + P+ + + +P
Sbjct: 3591 SEASTPSTPSVDRSTPVTTSTQS-NSTPTPPEVITLPMS-------TPSEVSTPLTIMPV 3642
Query: 809 GNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYS---SQSNTPTALTPV 865
V + G+ +T+P + P I S + S ++P + S T LT +
Sbjct: 3643 STTSVTISEAGTASTLPV---DTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTM 3699
Query: 866 PVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSST--------SLSSSTSTEGSGTM 917
PV V+ + G P V S+ +ISSS+T S+ ST G+ +
Sbjct: 3700 PVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTIL 3759
Query: 918 KKLDPAVGSPPAPPP--PPVPSPPFPCPADRSPFLP------PPPPVTDCSQGSPLPHSP 969
P P + P P V + A P P++ S+ S L +
Sbjct: 3760 VSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTV 3819
Query: 970 VFPPPPPEALIPFCSPPD--WCLSPPRPALSPILPDSPV-SLPLPPPLLP---SSEPPPA 1023
+ P I SP + +PP +P+L + S +P + S +
Sbjct: 3820 LISP------ISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERS 3873
Query: 1024 PPLDPKFMKDTRPP----FTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLR 1079
PL + T P + + P + PST + S P +P+ TT ++ ++
Sbjct: 3874 TPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPST-DTASTPTIPVATTISVSVITEG 3932
Query: 1080 PVRKNS--------GAEAAQLSERTAQEQRTPVAPQYHLK-PSAFLKSRNSTNEMESESQ 1130
+ + A + T TPV L PS S ++ E
Sbjct: 3933 STPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFT 3992
Query: 1131 PASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSR 1190
++T++ P + S G + + + S +T P+ SS S
Sbjct: 3993 TPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESS 4052
Query: 1191 KPPPISKKPKLFLVVPP--PQKDFAVEPAENVSEAL---RAVPSPTTGEEGSVHS 1240
+P I+ +PP P + P + S AV + TT + S +
Sbjct: 4053 RPSTITSH-----TIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRT 4102
Score = 39.7 bits (91), Expect = 0.024
Identities = 72/339 (21%), Positives = 125/339 (36%), Gaps = 34/339 (10%)
Query: 658 SLSRNISLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSG 717
S+ ++S+ A + P+ + +P ++ +L LI+ + S+ S
Sbjct: 3778 SVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPI------SVMSPSE 3831
Query: 718 SSPSQSPCSDLEEPWLPRSRSQS-------TVSAGSSMTSATTPNVYSLCGAT-PSQSDT 769
+S +P D P L +++ S T S + +TP L T P+
Sbjct: 3832 ASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPG 3891
Query: 770 SSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTS---SGVPTGNGP-------VRHVQEG 819
+S+ S T P +T + P +T+ S + G+ P V
Sbjct: 3892 ASIAS--TPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSS 3949
Query: 820 SRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNT-----PTALTPVPVFLKSVSP 874
+ P G P I S E + S SS +S S T P T P+ ++S
Sbjct: 3950 TADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMST 4009
Query: 875 ANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPP-P 933
A + + +S +S+ S +STS+++ T S + + + S PP P
Sbjct: 4010 APSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSR--PSTITSHTIPPTFP 4067
Query: 934 PVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFP 972
P S P + S + P T ++ P + FP
Sbjct: 4068 PAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFP 4106
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 82.4 bits (202), Expect = 3e-15
Identities = 160/708 (22%), Positives = 244/708 (34%), Gaps = 84/708 (11%)
Query: 835 KIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLIS 894
K S +K HR S S +S TP + KS + + P+ + + S
Sbjct: 210 KKSSKKKKHRSESESKKRKHRSPTPKSKR------KSKDKKRKRSRSTTPAPKSRRAHRS 263
Query: 895 SVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSP-PAPPPPPVPSPPFPCPADRSPFLPPP 953
+ + S+SS+ S S S + A SP PA PF P S P
Sbjct: 264 TSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSS 323
Query: 954 PPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPP 1013
P SP A P SP P PA +P+L + P P
Sbjct: 324 PETATKQPSSPYEDKDK-DKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLA 382
Query: 1014 LLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPS------TKEETSRP--PM 1065
P S+ P PP + +D PP + P+SS PPS ++ +S P P
Sbjct: 383 TTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPK 442
Query: 1066 PLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEM 1125
P + + + P KN A +R TP + A K S +
Sbjct: 443 PAPAPGSHREISSSPTSKNRSHGRA---KRDKSHSHTPSRRMGRSRSPATAKRGRSRSRT 499
Query: 1126 ESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAP--SAGEAEARPSPSTTPL 1183
++ + S ++S+ + + +R G SRSP P S R S +
Sbjct: 500 PTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGR-SRSPQRPGWSRSRNTQRRGRSRSAR 558
Query: 1184 PDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSR-E 1242
S SR P + S T G SR
Sbjct: 559 RGRSHSRSPATRGRS-----------------------------RSRTPARRGRSRSRTP 589
Query: 1243 AKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSAD 1302
A+ S ++ + + G + S +P+R + + V + PA S
Sbjct: 590 ARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR---TRSPVRRRSRSRSPARRS-- 644
Query: 1303 TGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHR 1362
G S + G + T A S + + G TP+R + R
Sbjct: 645 --GRSRSRTPARRGRSR-SRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGR 701
Query: 1363 SKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKAL 1422
S+ + L RR R+HS +P + S K S +RS +S++S + K+
Sbjct: 702 SRSRSLVRR------GRSHSRTPQRRGRSGSSSERKNKSRTSQRRS--RSNSSPEMKKSR 753
Query: 1423 LLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKN 1482
+ + SRS +S R A L +RS S SP P+ S P ++R +
Sbjct: 754 ISSRRSRSLSSPRSKAKSRLS-----LRRSLSGSSP-CPKQKSQTPPRRSRSGSSQ---- 803
Query: 1483 EGLMPRSLSFSGPRYGRSRT--PPSAASSRYSMRNRIQSSPMTVISEG 1528
P++ S + PR RS + PP S S ++ SSP + G
Sbjct: 804 ----PKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSG 847
Score = 65.9 bits (159), Expect = 3e-10
Identities = 87/309 (28%), Positives = 114/309 (36%), Gaps = 66/309 (21%)
Query: 731 PWLPRSRSQSTVSAGSS--MTSATTPNVYSLCGATPSQS--------DTSSVKSEYTDPW 780
P L R+RS++ SA S MTS P+ S G PSQS S V S ++D
Sbjct: 2400 PLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQS 2459
Query: 781 GYYIDYT----GMQEDPGNPAGGCSTSSG-------VPTGNGPVRHVQEGSRATMPQVPG 829
I T G Q ++S+G VP P V E +T Q P
Sbjct: 2460 RCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPS 2519
Query: 830 GSVKPKIMSPEKSHRVISPSSGYSSQSNTPT---------------------------AL 862
+ P K R S SS SS S++ + AL
Sbjct: 2520 ALAA---LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL 2576
Query: 863 TPVPVFLKSVSPANGKGKPKPKVP---ERKSSLISSVSISSSSTSLSSSTSTEGSGTMKK 919
VP + A +G+P P +R+SS SS S SSSS+S SSS+S+ S +
Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636
Query: 920 LDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPP---------PPVTDCSQGSPLPHSPV 970
+ S + P P P P SP PPP P+ L +SPV
Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPV 2696
Query: 971 ---FPPPPP 976
P P P
Sbjct: 2697 ERRRPSPQP 2705
Score = 63.2 bits (152), Expect = 2e-09
Identities = 213/976 (21%), Positives = 326/976 (33%), Gaps = 194/976 (19%)
Query: 711 SLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSS--MTSATTPNVYSLCGATPSQSD 768
S P + S S SP ++ PR RS S S+ S +TS TTP + S S
Sbjct: 902 STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR------RSRSVSP 955
Query: 769 TSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQV- 827
S+V+S + + G S+ P R GS + P+V
Sbjct: 956 CSNVESRLLPRYSH---------------SGSSSPDTKVKPETPPRQSHSGSISPYPKVK 1000
Query: 828 ----PG----GSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKG 879
PG GS P K V S S + ++ P + VS KG
Sbjct: 1001 AQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYF-GVSSLQLKG 1059
Query: 880 KPKPKVPERKSSLISSVSIS-SSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSP 938
+ + R + V S S S SL S + T G G + P +
Sbjct: 1060 QSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKG---------GRSRSSSPVTELAS 1110
Query: 939 PFPCPADRSPFLPPPPPVTDCS--QGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPA 996
P DR F P + S Q S +P +L L R
Sbjct: 1111 RSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSL----------LGQSRLE 1160
Query: 997 LSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESS--------- 1047
+ +S + LPP ++ PP KD PF +PESS
Sbjct: 1161 TA----ESKEKMALPPQEDATASPPR--------QKDKFSPFPVQDRPESSLVFKDTLRT 1208
Query: 1048 -----RGSLRPPSTKEETSRPPMPLITTEALQMVQL--RPVRKNSGAEAAQLSERTAQEQ 1100
G+ P TKE+ S P E +++V+ P + +++L E +
Sbjct: 1209 PPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNF 1268
Query: 1101 RTPVAPQYHLKPSAFLKSRNSTNE--MESESQPASVTS---------------------S 1137
+ +P+ +P+ L S ++ +E+ P+ +S S
Sbjct: 1269 ES--SPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENS 1326
Query: 1138 LPTPAKSSSQGDHGSAAERG--GPVSRSPGAPSAGEAEARPS-----PSTTPLPDSSPSR 1190
+P + + G G+ G V P + E PS ST SS
Sbjct: 1327 FGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSEL 1386
Query: 1191 KPPPISKKPKLFLVVPPPQKDFAVEPAENVSE-ALRAVPSPTTGEEGSVHSREAKESSAA 1249
P + K + +++S L AVP + E S S +
Sbjct: 1387 SPDAVEKA--------------GMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLP 1432
Query: 1250 QAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGES 1309
+ S + G+S G GS +PSR ++ P + P+ + D+ + ++
Sbjct: 1433 RTPSRRSRSGSS--PGLRDGSGTPSR--HSLSGSSPGMKDIPRTPSRGRSECDSSPEPKA 1488
Query: 1310 CLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLG 1369
+P+T S S + L N++ +TP R R+ + R LG
Sbjct: 1489 ----------LPQTPRPRSRSPSSPEL----NNKCLTPQRERSGSESSVDQKTVARTPLG 1534
Query: 1370 RRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDN----FKALLLK 1425
+R S S+ P +P + S +SP + +R+ S S + K+ L
Sbjct: 1535 QR-SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSP 1593
Query: 1426 KGSRSDTSARMSAAEMLKNTDPRFQR-SRSEPSPDAPESPS------SCSPSKNRRAQEE 1478
+ SRS +S + PR Q S S P P AP + S S SK R E
Sbjct: 1594 RRSRSGSSPEVKDKP---RAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
Query: 1479 WAKNEGLMP---------RSLSFSGPR-YGRSRTPPSAASSRYS----MRNRIQSSPMTV 1524
+ + P R S S P +SRTPP SSR S + R+ +
Sbjct: 1651 GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSA 1710
Query: 1525 ISEGEGEAVEPVDSIARGALGAAEGCSLDGLAREEMDEGGLLCGEGPAASLQPQAPGPVD 1584
S E + P ++ + E +R A P
Sbjct: 1711 SSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS-----------------ASSPRT 1753
Query: 1585 GTASAEGREPSPQCGG 1600
T S GR PSP+ G
Sbjct: 1754 KTTSRRGRSPSPKPRG 1769
Score = 62.4 bits (150), Expect = 3e-09
Identities = 169/739 (22%), Positives = 246/739 (33%), Gaps = 89/739 (12%)
Query: 503 LNAPANRENGSQAMPYNCRNNLAFPAHPQD-----VDGKSESSYSGGGGHSSSEPWEYKS 557
L P +G+ + P N A P QD V KSE H SSE E +
Sbjct: 1206 LRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMST 1265
Query: 558 SGNGRASPLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGH 617
S N +SP S +LDQ+ ++ ++ H H
Sbjct: 1266 S-NFESSP----------EVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEH 1314
Query: 618 GSGNLCNS---SDGFGNPRHSVINVFVGRAQKNQGDRSNYQDKSLSRNISLKKAKKPPLP 674
L NS + FG+P +N G + S + + P L
Sbjct: 1315 KE--LSNSPLRENSFGSPLEF----------RNSGPLGTEMNTGFSSEVK-EDLNGPFLN 1361
Query: 675 PSRTDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQSPCSDLEEPWLP 734
TD + ++S++ +G +E ++ + G S + SP D
Sbjct: 1362 QLETDPSLDMKEQSTRSSGHSSSELSPDAVEKA------GMSSNQSISSPVLDAVPRTPS 1415
Query: 735 RSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPG 794
R RS S S TP+ S G++P D S S ++ GM++ P
Sbjct: 1416 RERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSS----PGMKDIPR 1471
Query: 795 NPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHR---------- 844
P+ G S P + + SR+ P P + K ++P++
Sbjct: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRS--PSSP--ELNNKCLTPQRERSGSESSVDQKT 1527
Query: 845 VISPSSGYSSQSNTPTALTPVPVFL---KSVSPANGKGKPKPKVPERKSSLISSVSISSS 901
V G S+S + L P +S S ++ K K + P R+ S S S
Sbjct: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS 1587
Query: 902 STSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQ 961
+ LS S GS K P P P P P LP S+
Sbjct: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR----ALPRRSRSGSSSK 1643
Query: 962 G-SPLPH-------SPVFPPPPPEALIPFCSPPD---WCLSPPRPALSPILPDSPVSLPL 1010
G P P SP PP A S P+ +PPR S P+ L
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703
Query: 1011 PPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQP-ESSRGSLR-----PPSTKEETSRPP 1064
+S P P + R P +S +P E SR S R P TK + R
Sbjct: 1704 SRRSRSASSSPETRSRTPP--RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR 1761
Query: 1065 MPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNE 1124
P LQ + R R+ + + +R+ Q T Q S + R +
Sbjct: 1762 SPSPKPRGLQRSRSRSRREKT--RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSG 1819
Query: 1125 MESES---QPASVTSSLPTPAKS-SSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPST 1180
S S Q +S TSS +S + + R P A A R S S
Sbjct: 1820 YHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSR 1879
Query: 1181 TPLPDSSPSR-KPPPISKK 1198
TPL SR + P+S++
Sbjct: 1880 TPLISRRRSRSRTSPVSRR 1898
Score = 60.1 bits (144), Expect = 2e-08
Identities = 120/537 (22%), Positives = 192/537 (35%), Gaps = 68/537 (12%)
Query: 1031 MKDT-RPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEA 1089
MKD R P + +SS P T SR P ++ L L P R+ SG+E+
Sbjct: 1466 MKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSP----SSPELNNKCLTPQRERSGSES 1521
Query: 1090 AQLSERTA-----QEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQP---ASVTSSLPTP 1141
+ + A Q R+ + + +KPSA + R+ ES+S P A + L
Sbjct: 1522 SVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERS-----ESDSSPDSKAKTRTPLRQR 1576
Query: 1142 AKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKL 1201
++S S + S + SRS +P + + R +P DSSP K P P+
Sbjct: 1577 SRSGSSPEVDSKSRLSPRRSRSGSSPEVKD-KPRAAPRAQSGSDSSPEPKAPAPRALPRR 1635
Query: 1202 FLVV-------PPPQKDFAVEPA-------ENVSEALRAVPSPTTGEEGSVHSREAKESS 1247
P P+ + E + R+ P P T R ++ S
Sbjct: 1636 SRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSP 1695
Query: 1248 AAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEP----AENSADT 1303
+ + S S +P R + + P+ PA K + +S T
Sbjct: 1696 ELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPE--PAEKSRSSRRRRSASSPRT 1753
Query: 1304 GGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRS 1363
S G+ + + + + D + + SR R + + R
Sbjct: 1754 KTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRR 1813
Query: 1364 KRKVLG-------RRDSDDDHSRNH---SPSPPVTPTGAAPSLASPKQVGSIQRSIRKSS 1413
+R G R++S SR S +PP + + + S R+ +
Sbjct: 1814 RRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATH 1873
Query: 1414 TSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPSPDAPESPSSCSPSKNR 1473
S + L+ ++ SRS TS +S T +RSRS SP + S +P R
Sbjct: 1874 RRSRSRTPLISRRRSRSRTSP-VSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
Query: 1474 RAQEEWAKNEGLMPRSLSFSGPRYGRSRTPPSAASSRYS-------MRNRIQSSPMT 1523
R RS + + R RSRTPP S R+R ++SP+T
Sbjct: 1933 RRS-----------RSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPIT 1978
Score = 58.2 bits (139), Expect = 6e-08
Identities = 224/1010 (22%), Positives = 340/1010 (33%), Gaps = 148/1010 (14%)
Query: 651 RSNYQDKSLSRNISLKKAKKPPLPPSRTDS---LRRIPKKSSQCNGQVLN----ESLIAT 703
RSN + IS ++++ P S+ S LRR SS C Q S +
Sbjct: 742 RSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGS 801
Query: 704 LQHSLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCGAT 763
Q + P + S S P + P +S S+ S + S T P S+ T
Sbjct: 802 SQPKAKSRTPPRRSRSSSSPPPKQKSKT--PSRQSHSSSSPHPKVKSGTPPRQGSI---T 856
Query: 764 PSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRAT 823
Q++ SV + + D P + S+ V + P Q SR++
Sbjct: 857 SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPR---QSPSRSS 913
Query: 824 MPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKP 883
PQ VK I ++SH SG SS S + P +SVSP +
Sbjct: 914 SPQP---KVKAIISPRQRSH------SGSSSPSPSRVTSRTTPRRSRSVSPCSN------ 958
Query: 884 KVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCP 943
V R S SS T + T S + PP P + PCP
Sbjct: 959 -VESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCP 1017
Query: 944 ADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCS---------PPDWCLSPPR 994
++S V C L PP E+ S PD
Sbjct: 1018 QEKS----KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSS 1073
Query: 995 PAL------SPILPDSPVSLP---LPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSG-QP 1044
P + SP L + P P +E P+ + + P SG P
Sbjct: 1074 PEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSP 1133
Query: 1045 ESSR---GSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQR 1101
E SR S P+ + L T E+ + + L P E A S +++
Sbjct: 1134 EQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPP------QEDATASPPRQKDKF 1187
Query: 1102 TPVAPQYHLKPSAFLKSRNSTNEME-----SESQPASVTSSLPTPAKSSSQGDHGSAAER 1156
+P Q + S K T E S + S+LPT SS + E+
Sbjct: 1188 SPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPT---SSQDEELMEVVEK 1244
Query: 1157 GGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEP 1216
S P + +T +SSP + ++P + L + Q ++E
Sbjct: 1245 ----SEEPAGQILSHLSSELKEMSTSNFESSPE-----VEERPAVSLTLDQSQSQASLEA 1295
Query: 1217 AENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGS------ 1270
E VPS + G S E KE S + ++ G G+
Sbjct: 1296 VE--------VPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGF 1347
Query: 1271 MSPSRVEANVPMV-QPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSS 1329
S + + N P + Q + P+ +E + S+ G S LS D ++ S
Sbjct: 1348 SSEVKEDLNGPFLNQLETDPSLDMKEQSTRSS---GHSSSELS-PDAVEKAGMSSNQSIS 1403
Query: 1330 SEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTP 1389
S D + TPSR R++ + + RR SR+ S SP +
Sbjct: 1404 SPVLDAVPR-------TPSRERSSSASSPEMKDGLPRTPSRR------SRSGS-SPGLRD 1449
Query: 1390 TGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRF 1449
PS + S+ SS + + S D+S A P+
Sbjct: 1450 GSGTPS----------RHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKAL-------PQT 1492
Query: 1450 QRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRSRTPPSAASS 1509
R RS SP +PE + C + R+ E + ++ + R+ R G S+ S+
Sbjct: 1493 PRPRSR-SPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSA 1551
Query: 1510 RYSMRNRIQSSP------MTVISEGEGEAVEP-VDSIARGALGAAEGCSLDGLAREEMDE 1562
R+ SSP T + + P VDS +R L S ++
Sbjct: 1552 SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR--LSPRRSRSGSSPEVKDKPR 1609
Query: 1563 GGLLCGEGPAASLQPQAPGP------VDGTASAEGREPSPQCGGSLSEES 1606
G +S +P+AP P +S++GR PSP+ GS S ES
Sbjct: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE--GSSSTES 1657
Score = 54.7 bits (130), Expect = 7e-07
Identities = 115/507 (22%), Positives = 175/507 (34%), Gaps = 79/507 (15%)
Query: 1054 PSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSE-----------RTAQEQRT 1102
P KEET P TE Q+ +L + A +S+ R A+E +
Sbjct: 105 PGGKEET--PGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQ 162
Query: 1103 PVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSR 1162
P AP+ KP + ++ +S+ S P K + D G +E P R
Sbjct: 163 P-APEPP-KPYSLVRESSSSR------------SPTPKQKKKKKKKDRGRRSESSSP--R 206
Query: 1163 SPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSE 1222
S+ + + R + SP+ K SK K ++ + PA
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKR-------KRSRSTTPAPKSRR 259
Query: 1223 ALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPM 1282
A R+ S S + ++S +++ S A T+ L G + S R E + P
Sbjct: 260 AHRST---------SADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPF 310
Query: 1283 VQPDV-------SPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDF 1335
+P SP ++P+ D D + + + + PE ++ G A
Sbjct: 311 SEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPS--PERSSTGPEPPAPTP 368
Query: 1336 LKED--------------GNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNH 1381
L + + V PS T D + +S K+ S S
Sbjct: 369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRD--RSPPKSPEKL---PQSSSSESSPP 423
Query: 1382 SPSPPVTPTGAAPSLASPKQVGS--IQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAA 1439
SP P A+ S SPK + R I S TS + + S S T +R
Sbjct: 424 SPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGR 483
Query: 1440 EMLKNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFS--GPRY 1497
T R RSRS S S + R+ + W ++ R S S P +
Sbjct: 484 SRSPATAKR-GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGW 542
Query: 1498 GRSRTPPSAASSRYSMRNRIQS-SPMT 1523
RSR SR + R R S SP T
Sbjct: 543 SRSRNTQRRGRSRSARRGRSHSRSPAT 569
Score = 53.1 bits (126), Expect = 2e-06
Identities = 100/509 (19%), Positives = 169/509 (33%), Gaps = 49/509 (9%)
Query: 1034 TRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLS 1093
T P + +S S T SR T AL P G A S
Sbjct: 252 TPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFS 311
Query: 1094 ERTAQEQRTPVAPQYHLK-PSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGS 1152
E + P +P+ K PS+ + ++ + +S ++P+ P+P +SS+ + +
Sbjct: 312 EPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPS------PSPERSSTGPEPPA 365
Query: 1153 A----AERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPP 1208
AER G + + P +P D SP + P + + P P
Sbjct: 366 PTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425
Query: 1209 QKDFAVEPAENVSEALRAVPSPTTGEE--GSVHSREAKESSAAQAGSHATHPGTSVLEGG 1266
Q A + E+ + P+P + E S S+ A + SH+ P +
Sbjct: 426 QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR 485
Query: 1267 AAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAA 1326
+ + R + P + Q + ++ Q+ G + P+
Sbjct: 486 SPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSA------------QRWGRSRSPQRRGR 533
Query: 1327 GSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPP 1386
S + + SR R T+ RS+ GR S +R S S
Sbjct: 534 SRSPQRPGW------------SRSRNTQRR----GRSRSARRGRSHSRSPATRGRSRSRT 577
Query: 1387 VTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTD 1446
G + S ++ + R+ S S + + SRS T AR + +
Sbjct: 578 PARRGRSRSRTPARRRSRSRTPTRRRSRSRTPAR----RGRSRSRTPARRRS----RTRS 629
Query: 1447 PRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRSRTPPSA 1506
P +RSRS S +P++ R++ G RSRTP
Sbjct: 630 PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARR 689
Query: 1507 ASSRYSMRNRIQSSPMTVISEGEGEAVEP 1535
SR R +S +++ G + P
Sbjct: 690 GRSRSRTPRRGRSRSRSLVRRGRSHSRTP 718
Score = 52.8 bits (125), Expect = 3e-06
Identities = 155/726 (21%), Positives = 237/726 (32%), Gaps = 83/726 (11%)
Query: 816 VQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPA 875
++ SR+ P+ G P R S SS S+S TP A
Sbjct: 2050 IRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATR------------ 2097
Query: 876 NGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTST---EGSGT----MKKLDPAVGSPP 928
N G P V S + S S T L S E G+ M L A GS
Sbjct: 2098 NHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMM 2157
Query: 929 APPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPP---------PPPEAL 979
P P +P + +T S G+ P + P P L
Sbjct: 2158 DGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPL 2217
Query: 980 IPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFT 1039
+ + P L+ PA S + L S+ P P + D+R P
Sbjct: 2218 MSLRTAPAANLASRIPAASAAAMN-----------LASARTPAIPTAVN--LADSRTPAA 2264
Query: 1040 NSGQPESSRGSLRPPSTKE--ETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTA 1097
+ +S + PS + P P + + +G+ +
Sbjct: 2265 AAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYP 2324
Query: 1098 QEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERG 1157
RTP AP SA L S + + S T++ PA +S A
Sbjct: 2325 SSSRTPQAPA-----SANLVGPRSAHATAPVNIAGSRTAAALAPASLTSAR---MAPALS 2376
Query: 1158 GPVSRSPGAPSAG--EAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLV-VPPPQKDFAV 1214
G SP P + R SP PL D + SR PP + ++ P P
Sbjct: 2377 GANLTSPRVPLSAYERVSGRTSP---PLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQ 2433
Query: 1215 EPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPS 1274
P++++ + P S SR + AGS + L GA + + S
Sbjct: 2434 APSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQS-------LSSGAVATTTSS 2486
Query: 1275 RVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACD 1334
+ N + P +P + E A TG S L+ A E ++ SSS +
Sbjct: 2487 AGDHNGMLSVP--APGVPHSDVGEPPASTGAQQPSALAALQPAK---ERRSSSSSSSSSS 2541
Query: 1335 FLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAP 1394
+ + S ++ D + + +V +R PSP P A
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR----------VPSPTPAPKEAVR 2591
Query: 1395 SLASPKQV-GSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSR 1453
P+ +R SS+SS + + S S +S+ S++ ++ S
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
Query: 1454 SEPSPDAPESPSSCS--PSKNRRAQEEWAKNEGLM-PRSLSFSGPRYGRSRTPPSAASSR 1510
++P P A P+S P RR++ + L RSLS+S R PS +
Sbjct: 2652 AKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQ 2711
Query: 1511 YSMRNR 1516
S R
Sbjct: 2712 SSSSER 2717
Score = 52.8 bits (125), Expect = 3e-06
Identities = 110/534 (20%), Positives = 191/534 (35%), Gaps = 50/534 (9%)
Query: 848 PSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLS- 906
P++ + S TP A + + SP + + ++ +V+++ + T +
Sbjct: 2251 PTAVNLADSRTPAAAAAMNL----ASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAAL 2306
Query: 907 SSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLP 966
++ S GSGT P + P+ P RS P + + L
Sbjct: 2307 AALSLTGSGT----PPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALA 2362
Query: 967 HSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPS--SEPPPAP 1024
+ + + P S + L+ PR LS VS PPLL S PP+
Sbjct: 2363 PASL----TSARMAPALSGAN--LTSPRVPLSAY---ERVSGRTSPPLLDRARSRTPPSA 2413
Query: 1025 PLDPKFMKDTRP-PFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRK 1083
P + + P P + GQ S SL PP+ + S P + Q PV
Sbjct: 2414 PSQSRMTSERAPSPSSRMGQAPSQ--SLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471
Query: 1084 N----SGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLP 1139
+ SGA A S V P + S + ST QP+++ + P
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSV-PAPGVPHSDVGEPPASTGAQ----QPSALAALQP 2526
Query: 1140 TPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPL-PDSSPSRKPPPISKK 1198
+ SS S++ S S + S+G + + S+ P+ P+ + R P P
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP---- 2582
Query: 1199 PKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHP 1258
P P++ + A R S ++ S S + SS++ + S ++
Sbjct: 2583 ------TPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636
Query: 1259 GTSVLEGGAAGSMSPSRVEAN-VPMVQPDVSPAPKQ------EEPAENSADTGGDGESCL 1311
+S ++ S SP++ +P P P + +P ++ D+ S +
Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPV 2696
Query: 1312 SQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKR 1365
++ + + SSSE + G+ + R R T HRS R
Sbjct: 2697 ERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750
Score = 51.2 bits (121), Expect = 8e-06
Identities = 275/1301 (21%), Positives = 425/1301 (32%), Gaps = 193/1301 (14%)
Query: 402 VSPHATYSTSIIPNATLSSSSEVIAIPTAQSAGQRESKSSGSSHARIKSRDHLISRHAVK 461
VSP + + ++P + S SS ++ ++ S S + ++K+
Sbjct: 953 VSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKA----------- 1001
Query: 462 GDPQSPGRHWNEGHATILSQDLDPHSPGE--PALLSLCDSAVPLNAPANRENGSQAMPYN 519
Q+P G + Q+ S + P LSLC P G ++
Sbjct: 1002 ---QTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLK 1058
Query: 520 CRNNLAFPAHPQD---------------VDGKSESSYSGGGGHSSSEPWEYKSSGNGRAS 564
++ + P H D + KS++S GG SSS E S S
Sbjct: 1059 GQSQTS-PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASR-----S 1112
Query: 565 PLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGNLC- 623
P++ +S S S +Q+ + D+ S + D + ++ +
Sbjct: 1113 PIRQDRGE--FSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMAL 1170
Query: 624 -NSSDGFGNPRHSVINVFVGRAQKNQGDRSNYQDKSLSRNISLKKAKKPPLPPSRTDSLR 682
D +P QK++ QD+ S + + PP S S
Sbjct: 1171 PPQEDATASPPR----------QKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSP 1220
Query: 683 RIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTV 742
+++S +E L+ ++ S + P + + ST
Sbjct: 1221 ETKEQNSALPTSSQDEELMEVVEKS--------------EEPAGQILSHLSSELKEMSTS 1266
Query: 743 SAGSSMTSATTPNVYSLCGATPSQSDTSSVK-SEYTDPWGYYIDYTGMQEDPGNPAGGCS 801
+ SS P V + SQ+ +V+ WG +E +P S
Sbjct: 1267 NFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENS 1326
Query: 802 TSSGVPTGN-GPV-RHVQEGSRATMPQVPGG------SVKPKIMSPEKSHRVISPSSGYS 853
S + N GP+ + G + + + G P + E+S R SSG+S
Sbjct: 1327 FGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTR----SSGHS 1382
Query: 854 SQSNTPTALTPVPVFL-KSVSPANGKGKPKPKVPERKSSLISSV-------SISSSSTSL 905
S +P A+ + +S+S P+ ER SS S + S S S
Sbjct: 1383 SSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSG 1442
Query: 906 SSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPL 965
SS +GSGT + + SP P PS D SP P P T P
Sbjct: 1443 SSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRG-RSECDSSPE-PKALPQT------PR 1494
Query: 966 PHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPP--PLLPSSEPPPA 1023
P S P PE + CL+P R +S V PL S +
Sbjct: 1495 PRSR--SPSSPEL-------NNKCLTPQRERSGS---ESSVDQKTVARTPLGQRSRSGSS 1542
Query: 1024 PPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRK 1083
LD K + + P+S + P + + P E +L P R
Sbjct: 1543 QELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP------EVDSKSRLSPRRS 1596
Query: 1084 NSGAE--------AAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVT 1135
SG+ AA ++ + P AP P +S S +S
Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE 1656
Query: 1136 SSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSP-SRKPPP 1194
SS P KS + A RG S P S R S S+ L + SR+
Sbjct: 1657 SSPEHPPKSRT-------ARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709
Query: 1195 ISKKPKLFLVVPPPQKDF----AVEPAENV--SEALRAVPSP---TTGEEGSVHSREAKE 1245
S P+ PP + + EPAE S R+ SP TT G S + +
Sbjct: 1710 ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRG 1769
Query: 1246 SSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDV------------SPAPKQ 1293
+++ S T+ + S S SR SPA ++
Sbjct: 1770 LQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQE 1829
Query: 1294 EEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRT- 1352
+ G S++ + S S A SR R+
Sbjct: 1830 SSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSR 1889
Query: 1353 --TEDLFAAIHRSKRKVLGRRD----SDDDHSRNHSPSPPVT--------PTGAAPSLAS 1398
T + RS+ V RR S R+ S +PPVT PT S +
Sbjct: 1890 SRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSR 1949
Query: 1399 PKQVG---SIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSE 1455
V S R+ + S + + + ++ SRS TS + + +RSRS
Sbjct: 1950 TPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSR 2009
Query: 1456 PSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGP-----RYGRSRTPPSAASSR 1510
SP S +P RR L+PR S S R RSRTP +A R
Sbjct: 2010 TSPVTRRRSRSRTPPAIRRRSR---SRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKR 2066
Query: 1511 YSMRNRIQSSPMTVISEGEGEAVEPVDSIARGALGAAEGCSLDGLAREEMDEGGLLCGEG 1570
R S P G + + S A G +A ++ + C
Sbjct: 2067 SLTR----SPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVA---LNSSRMSCFSR 2119
Query: 1571 PAASLQP----QAPGPVDGTASAEGREPS---PQCGGSLSE 1604
P+ S P ++PG ++ S+ R P Q GGS+ +
Sbjct: 2120 PSMSPTPLDRCRSPGMLEPLGSS--RTPMSVLQQAGGSMMD 2158
Score = 51.2 bits (121), Expect = 8e-06
Identities = 117/560 (20%), Positives = 177/560 (31%), Gaps = 105/560 (18%)
Query: 990 LSPPRPALSPILPD--SPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESS 1047
L+ PR A++P + P + P L + P A L + + P T + P SS
Sbjct: 2270 LASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAA--LAALSLTGSGTPPTAANYPSSS 2327
Query: 1048 RGSLRPPSTK---EETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPV 1104
R P S ++ P+ + L P S A LS R P+
Sbjct: 2328 RTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPL 2387
Query: 1105 APQYHLKPSA---FLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVS 1161
+ + L S + SQ + P+P+ Q S
Sbjct: 2388 SAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQP 2447
Query: 1162 RSPGAPSAGEAEARPS-PSTTPLPDSSPSRKPPPISKKPKL-----FLVVPPP---QKDF 1212
RSP PSA ++R TTP+ S + L VP P D
Sbjct: 2448 RSP-VPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDV 2506
Query: 1213 AVEPAENVSEALRAVPS--PTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGS 1270
PA ++ A+ + P S S + SS++ + S ++ + + GS
Sbjct: 2507 GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGS 2566
Query: 1271 MSPSRVEANVPMVQPDVSPAPKQE---------EPAENSADTGGDGESCLSQQDGAAGVP 1321
P + E + V P +PAPK+ PA+ + S S ++
Sbjct: 2567 SLPVQPEVALKRV-PSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS 2625
Query: 1322 ETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNH 1381
++++ SSS + S S +
Sbjct: 2626 SSSSSSSSSSSSS--------------------------------------SSSSSSSSS 2647
Query: 1382 SPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEM 1441
SPSP A P ASPK+ +R R D+ R S S E
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL---------RDSRSLSYSPVE- 2697
Query: 1442 LKNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRSR 1501
R R P P + SS S +RR Q +++ P + R R
Sbjct: 2698 ---------RRRPSPQPSPRDQQSSSSERGSRRGQRGDSRS------------PSHKRRR 2736
Query: 1502 TPPSAASSRYSMRNRIQSSP 1521
PS MR+R SP
Sbjct: 2737 ETPSPR----PMRHRSSRSP 2752
Score = 43.9 bits (102), Expect = 0.001
Identities = 141/709 (19%), Positives = 229/709 (32%), Gaps = 92/709 (12%)
Query: 841 KSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISS 900
+S SP + S+S TP A+ P +P ++S S ++I
Sbjct: 2005 RSRSRTSPVTRRRSRSRTPPAIR------------RRSRSRTPLLPRKRSRSRSPLAIRR 2052
Query: 901 SSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVT-DC 959
S S + T+ G ++ + PA+ A S PA R+ PPV +
Sbjct: 2053 RSRSRTPRTA-RGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNS 2111
Query: 960 SQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSE 1019
S+ S + P P P P L R +S + + P P +P +
Sbjct: 2112 SRMSCFSRPSMSPTPLDRCRSPGMLEP---LGSSRTPMSVLQQAGGSMMDGPGPRIPDHQ 2168
Query: 1020 PPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLR 1079
P N Q SR +L + T+RPP +
Sbjct: 2169 RTSVPE--------------NHAQ---SRIALALTAISLGTARPPPSM------------ 2199
Query: 1080 PVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLP 1139
AA L+ R +Q P+A L SR + + ++ T ++P
Sbjct: 2200 --------SAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIP 2251
Query: 1140 TPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKP 1199
T + +AA R+ APSA A P T P + + +R P ++
Sbjct: 2252 TAVNLADSRTPAAAAAMNLASPRTAVAPSAVNL-ADPRTPTAPAVNLAGARTPAALAALS 2310
Query: 1200 KLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPG 1259
PP ++ + A + P + + + ++AA A + T
Sbjct: 2311 LTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSAR 2370
Query: 1260 TSVLEGGA---------------AGSMSP---SRVEANVPMVQPDVSPAPKQEEPAENSA 1301
+ GA +G SP R + P P S + P+ +S
Sbjct: 2371 MAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSR 2430
Query: 1302 DTGGDGESCL--SQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAA 1359
+S L +Q + VP + S G+ + + + TT A
Sbjct: 2431 MGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS--AG 2488
Query: 1360 IHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNF 1419
H V D PP + PS + Q +RS SS+SS +
Sbjct: 2489 DHNGMLSVPAPGVPHSDVG-----EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSS 2543
Query: 1420 KALLLKKGSRSDTSARMSAAE-MLKNTDPRFQRSRSEPSPDAPES------PSSCSPSKN 1472
+ S S + + S +E P R AP+ P +P+K
Sbjct: 2544 SSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKR 2603
Query: 1473 RRAQEEWAKNEGLMPRSLSFSGPRYGRSRTPPSAASSRYSMRNRIQSSP 1521
+R + + S S S S + S++SS S + SSP
Sbjct: 2604 KRRSSSSSSSSS---SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649
Score = 38.1 bits (87), Expect = 0.069
Identities = 72/340 (21%), Positives = 131/340 (38%), Gaps = 35/340 (10%)
Query: 1282 MVQPDVSPAPKQEEPAENSADTGGDGESCLSQQD-----GAAGVPETNAAGSSSEACDFL 1336
+++ DV+P K+E P + A T + L+++ A G+ ++ GSS +
Sbjct: 98 LLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRA 157
Query: 1337 KEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSL 1396
+E P +P + ++ K ++ D R+ S SP ++
Sbjct: 158 RE-AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKK 216
Query: 1397 ASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSA-------RMSAAEMLKNTDPRF 1449
+ S +R R + S +K SRS T A R ++A+ ++D
Sbjct: 217 KHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSR 276
Query: 1450 QRSRSEPSPDAPESPS--SCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRSRTPPSAA 1507
RSRS + + + S SP+ RR + + +E P + S P T
Sbjct: 277 SRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE---PGTTSTQRP--SSPETATKQP 331
Query: 1508 SSRYSMRNR-------IQSSPMTVISEGEGEAVEPVDSIARGALGAAEGCSLDGLAREEM 1560
SS Y +++ + SP S E P +A G+ + + L++E +
Sbjct: 332 SSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPV 391
Query: 1561 D---EGGLLCGEGPAASLQPQAPGPVDGTASAEGREPSPQ 1597
+ E P P++P + ++S+E PSPQ
Sbjct: 392 NPPSEASPTRDRSP-----PKSPEKLPQSSSSESSPPSPQ 426
Score = 36.6 bits (83), Expect = 0.20
Identities = 266/1324 (20%), Positives = 427/1324 (32%), Gaps = 155/1324 (11%)
Query: 349 DMNGTFLYQ-RGHPQADENLGHLGGASGTGTLLRPKSQELRHFES-ENIMSPACVVSPHA 406
D+NG FL Q P D + + + L P + E S ++I SP P
Sbjct: 1354 DLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPR- 1412
Query: 407 TYSTSIIPNATLSSSSEVIAIPTAQSAGQRESKSSGSSHARIKSRDHLISRHAVKGD--- 463
+ S +++ SS +P S R S G ++ SRH++ G
Sbjct: 1413 --TPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPG-----LRDGSGTPSRHSLSGSSPG 1465
Query: 464 ----PQSPGRHWNEGHAT----ILSQDLDPHS--PGEPALLSLCDSAVPLNAPANRENGS 513
P++P R +E ++ L Q P S P P L + C + P +GS
Sbjct: 1466 MKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLT------PQRERSGS 1519
Query: 514 QAMPYNCRNNLAFPAHPQDVDGKSESSYSGGGGHSSSEPWEYKSSGNGRASPLKPHLATP 573
++ + + P + G S+ S+ P E S + S K
Sbjct: 1520 ESS-VDQKTVARTPLGQRSRSGSSQEL----DVKPSASPQERSESDSSPDSKAKTRTPLR 1574
Query: 574 GYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGNLCNSSDGFGNPR 633
S S+ S + S + E D A+ SG S + PR
Sbjct: 1575 QRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPR 1634
Query: 634 HSVI-NVFVGRAQKNQGDRSNYQDKSLSRNISLKKAKKPPLPPSRTDSLRRIPKKSSQCN 692
S + GR +G S + P +T S ++SS+ +
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694
Query: 693 GQVLNESLIATLQHSLQLSLPGKSGSSPS--QSPCSDLEEPWLPRSRSQSTVSAGSSMTS 750
++ ++ ++ S S +S + P +SP EP +SRS + SS +
Sbjct: 1695 PELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP-AEKSRSSRRRRSASSPRT 1753
Query: 751 ATTPNVYSLCGATPS------QSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSS 804
TT S G +PS Q S + E T T + D + S
Sbjct: 1754 KTT----SRRGRSPSPKPRGLQRSRSRSRREKTR--------TTRRRDRSGSSQSTSRRR 1801
Query: 805 GVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTP 864
V + G + P + S + R +P + +S + T+ P
Sbjct: 1802 QRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTS-RKRSRSRTSPAP 1860
Query: 865 VPVFLKSVSPANGKGKPK--PKVPERKS-SLISSVSI--SSSSTSLSSSTSTEGSGTMKK 919
SPA + P + R+S S S VS S S TS++ S + + +
Sbjct: 1861 WKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSR 1920
Query: 920 LDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEAL 979
+PP P RS PPVT S P PV
Sbjct: 1921 RRSRSRTPPVTRRRSRSRTPTTRRRSRSR----TPPVTRRRSRSRTP--PVTRRRSRSRT 1974
Query: 980 IPFCSPPDWCLSPP------RPALSPILPDSPVSLPLPPPLLPS-SEPPPA--------P 1024
P + P R SP+ S P S S PPA
Sbjct: 1975 SPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRT 2034
Query: 1025 PLDPKFMKDTRPPF-----TNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLR 1079
PL P+ +R P + S P ++RG + T PP
Sbjct: 2035 PLLPRKRSRSRSPLAIRRRSRSRTPRTARGK------RSLTRSPPA-------------- 2074
Query: 1080 PVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLP 1139
+R+ S + ++ R+A TP A + H + NS+ M S+P+ + L
Sbjct: 2075 -IRRRSASGSSSDRSRSA----TPPATRNHSGSRTPPVALNSSR-MSCFSRPSMSPTPLD 2128
Query: 1140 TPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKP 1199
GS+ + ++ G+ G P T +P++ +
Sbjct: 2129 RCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAI 2188
Query: 1200 KLFLVVPPPQKDFAVEPAENVSEALRAVP--SPTTGEEGSVHSREAKESSAAQAGSHATH 1257
L PPP A A +S+ VP S T ++ SR S+AA + A
Sbjct: 2189 SLGTARPPPSMS-AAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASART 2247
Query: 1258 PGTSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGA 1317
P A S +P+ A + + P + AP A+ T ++ A
Sbjct: 2248 PAIPTAVN-LADSRTPAAAAA-MNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAA 2305
Query: 1318 AGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDH 1377
+G+ A ++ PS RT + +A R +
Sbjct: 2306 LAALSLTGSGTPPTAANY-----------PSSSRTPQAPASANLVGPRSAHATAPVNIAG 2354
Query: 1378 SRNHSPSPPVTPTGA--APSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSAR 1435
SR + P + T A AP+L+ S LL + SR+ SA
Sbjct: 2355 SRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAP 2414
Query: 1436 MSA---AEMLKNTDPRFQRSRSE----PSPDAPESP--------SSCSPSKNRRAQEEWA 1480
+ +E + R ++ S+ P+ D P SP S C ++ +
Sbjct: 2415 SQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQS 2474
Query: 1481 KNEGLMPRSLSFSGPRYGRSRTPP-----SAASSRYSMRNRIQSSPMTVIS---EGEGEA 1532
+ G + + S +G G P S + Q S + + E +
Sbjct: 2475 LSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSS 2534
Query: 1533 VEPVDSIARGALGAAEGCSLDGLAREEMDEGGLLCGEGPAASLQPQAPGPVDGTASAEGR 1592
S + + ++ S + EG L + A + +P P A EGR
Sbjct: 2535 SSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR 2594
Query: 1593 EPSP 1596
P P
Sbjct: 2595 PPEP 2598
Score = 34.3 bits (77), Expect = 1.00
Identities = 54/254 (21%), Positives = 88/254 (34%), Gaps = 15/254 (5%)
Query: 645 QKNQGDRSNYQDKSLSRNISLKKAKKPPLPPSRTDSLRRIPKKSSQCNGQ---VLNESLI 701
+ + RS D + S + S +++ T R P +S G+ +E
Sbjct: 256 KSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGT 315
Query: 702 ATLQHSLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNVYSLCG 761
+ Q K SSP + D +E R S+ A TP + G
Sbjct: 316 TSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHG 375
Query: 762 ATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNP--AGGCSTSSGVPTGNGPV---RHV 816
+P T+ + E +P T + P +P S+S P P RH
Sbjct: 376 GSPQPLATTPLSQEPVNP-PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHA 434
Query: 817 QEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPAN 876
+ P GS + SP +R + S S+TP+ +S SPA
Sbjct: 435 SSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMG-----RSRSPAT 489
Query: 877 GK-GKPKPKVPERK 889
K G+ + + P ++
Sbjct: 490 AKRGRSRSRTPTKR 503
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 82.0 bits (201), Expect = 4e-15
Identities = 191/856 (22%), Positives = 287/856 (33%), Gaps = 131/856 (15%)
Query: 666 KKAKKPPLPPSR-TDSLRRIPKKSSQCNGQVLNESLIATLQHSLQLS----LPGKSGSSP 720
+K K PLPP R D PK ++ G+ E ++ L L+ + P P
Sbjct: 154 RKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEP 213
Query: 721 SQSPCSDLEEPWLP----RSRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEY 776
S S P P R + Q+ V A +++ T P P + T S K +
Sbjct: 214 STPRRSRGRPPGRPAGPCRRKQQAVVVAEAAV---TIPKPEPPPPVVPVKHQTGSWKCK- 269
Query: 777 TDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNG---------PVRHVQEGSRATMPQV 827
G PG P G +S G G G ++ V + M Q+
Sbjct: 270 ----------EGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQL 319
Query: 828 PGGSVKPKIMSP-EKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVP 886
G + E+S + + S Q + P + K + + + K +
Sbjct: 320 SLGLESGQGQGQHEESWQDVPQRRVGSGQGGS-------PCWKKQEQKLDDEEEEKKEEE 372
Query: 887 ERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFP-CPAD 945
E+ + + + ++ E L P SPP P PPP SPP P CP
Sbjct: 373 EKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCP-- 430
Query: 946 RSPFLPPPPPVTDCSQGSPLPHSPVFPPP--------PPEALIPFCS-----PPDWCLSP 992
PPPPPV+ PLP P PPP PP + CS PP L+P
Sbjct: 431 -----PPPPPVSP----PPLPSPP--PPPAQEEQEESPPPVVPATCSRKRGRPP---LTP 476
Query: 993 PRPALSPILPDSP--VSLPLPPPLLPSSEPP-PAPPLDPK---FMKDTRPPFTNSGQPES 1046
+ A P S P P P + PP +P + PK F+K+ R S
Sbjct: 477 SQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARS 536
Query: 1047 SRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAP 1106
SR P +E PP P V++ PV + + + + A P AP
Sbjct: 537 SRVIKTPRRFMDED--PPKP-------PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP 587
Query: 1107 QYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGA 1166
P + R S E + S+T LP P P P A
Sbjct: 588 TPPSTPVPLPEKRRSILR-EPTFRWTSLTRELPPPP----------------PAPPPPPA 630
Query: 1167 PSAGEAEARPS--PSTTPLPDSSPSR----------KPPPISKKPKLFLVVPPPQKDFAV 1214
PS A A S P P +PS PPP+ P+ PPP D
Sbjct: 631 PSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLG-APEAPEPEPPPADDSPA 689
Query: 1215 EPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPS 1274
EP + P + + A A S+ +L+ ++
Sbjct: 690 EPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQ--PLQALQTQ 747
Query: 1275 RVEANVPMVQPDVSPAPK-QEEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEAC 1333
+ +P QP + P P Q+ P A G G LS GV E +
Sbjct: 748 LLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLS------GVEEKMFSLLKRAKV 801
Query: 1334 DFLKEDGNDE-----VMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVT 1388
K D + M S E++ A+ + + R + + ++ PS P +
Sbjct: 802 QLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPES 861
Query: 1389 PTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSAR-MSAAEMLKNTDP 1447
P P + + ++ ++ D + L R D + S+A ++
Sbjct: 862 PV-QGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPS 920
Query: 1448 RFQRSRSEPSPDAPES 1463
R +R + E + ES
Sbjct: 921 RSRRGKVEAAGPGGES 936
Score = 54.7 bits (130), Expect = 7e-07
Identities = 157/758 (20%), Positives = 248/758 (32%), Gaps = 142/758 (18%)
Query: 836 IMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVS---PANGKGKPKPKVPERKSSL 892
++S S + +P P + PV ++ P + P P P +
Sbjct: 531 VVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPP 590
Query: 893 ISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPP-VPSPPFPCPADRSPFLP 951
+ V + S+ + + ++L P PPAPPPPP PP P + R P L
Sbjct: 591 STPVPLPEKRRSILREPTFRWTSLTRELPPP---PPAPPPPPAPSPPPAPATSSRRPLLL 647
Query: 952 PPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLP-- 1009
P T + S + PPP P PP SP P + + +SLP
Sbjct: 648 RAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRF 707
Query: 1010 ---LPPPLLPSSEPPPAPPLD--PKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPP 1064
+ P+ P AP L P+ P + Q + +L PP + + P
Sbjct: 708 APVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPL-QALQTQLLPQALPPPQPQLQPPPSP 766
Query: 1065 --MPLITTEALQMVQLRPVRKNSGAEAAQLS---------ERTAQEQRTPVAPQYHLKP- 1112
MP + + V P+ SG E S + Q+Q+ VA L P
Sbjct: 767 QQMPPLEKARIAGVGSLPL---SGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPG 823
Query: 1113 ------SAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGA 1166
+ +K + + SE + P+ +S QG R V+ G
Sbjct: 824 GQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVAL--GQ 881
Query: 1167 PSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRA 1226
A E P S PL D ++D A E + SE +
Sbjct: 882 ARAMVPEDVPRLSALPLRD-----------------------RQDLATEDTSSASET-ES 917
Query: 1227 VPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPD 1286
VPS SR K +A PG G+ G+++ +
Sbjct: 918 VPS---------RSRRGKVEAAG--------PGGESEPTGSGGTLAHT------------ 948
Query: 1287 VSPAPKQEEPAENSADTG----GDGESCLSQQDGAAGV-----PETNAAGSSSEACDFLK 1337
P++ P+ + G CL QD + V P+ + + C + K
Sbjct: 949 ----PRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRK 1004
Query: 1338 EDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLA 1397
D R E L A R+ K L DSD+ S SP PP GA
Sbjct: 1005 CD-------KIEARKMERL-AKKGRTIVKTLLPWDSDE--SPEASPGPPGPRRGAGAGGP 1054
Query: 1398 SPKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPS 1457
+ V + + +LL +K +R R S ++ +++D +
Sbjct: 1055 REEVV---------AHPGPEEQDSLLQRKSARRCVKQRPS-YDIFEDSD--------DSE 1096
Query: 1458 PDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRSRTPPSAASSRYSMRNRI 1517
P P +P +P +NE +P S PR + + R ++ +
Sbjct: 1097 PGGPPAPRRRTP----------RENELPLPEPEEQSRPRKPTLQPVLQLKARRRLDKDAL 1146
Query: 1518 QSSPMTVISEGEGEAVEPVDSIARGALGAAEGCSLDGL 1555
P G + D + R + E C L+ +
Sbjct: 1147 APGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENV 1184
Score = 52.4 bits (124), Expect = 4e-06
Identities = 114/452 (25%), Positives = 151/452 (33%), Gaps = 97/452 (21%)
Query: 922 PAVGSPPAPPP--PPVPSPPFPCPADRS----PFLPPPPPVTDCSQGSPLPHSPVFPPPP 975
P+ GSP + P V P FP P RS P P PPP S PL SP PP
Sbjct: 1886 PSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASP--PLKTSPQLRVPP 1943
Query: 976 PEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPP------PAPPLDPK 1029
P +++ +P L+PP PA SP P P L P E A LD
Sbjct: 1944 PTSVVTALTPTSGELAPPGPAPSP---------PPPEDLGPDFEDMEVVSGLSAADLDFA 1994
Query: 1030 FMKDTRPPFTN----SGQPESSRGSLRPPSTKEETSRPP----------------MPLIT 1069
PF +G SS G P + EE S P P T
Sbjct: 1995 ASLLGTEPFQEEIVAAGAMGSSHGG--PGDSSEEESSPTSRYIHFPVTVVSAPGLAPSAT 2052
Query: 1070 TEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPV------------APQYHLKPSAFLK 1117
A ++ QL V + +EA + + + Q TP A +P L
Sbjct: 2053 PGAPRIEQLDGVDDGTDSEAEAVQQ--PRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLP 2110
Query: 1118 S-------RNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPV---SRSPGAP 1167
S +N + + P + P + SQ G A P + PGAP
Sbjct: 2111 SEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAP 2170
Query: 1168 SAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFL-------VVPPPQKDFAVEPAENV 1220
P+P P + K ++K ++F+ VPPP K + P +
Sbjct: 2171 GVRVLSLGPAPE----PPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISP 2226
Query: 1221 SEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANV 1280
+ P+ T G + A P T VL G A SP R V
Sbjct: 2227 T-----APTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPA---SPPRQAIRV 2278
Query: 1281 PMVQ---------PDVSPAPKQEEPAENSADT 1303
V P AP+ +E E S DT
Sbjct: 2279 KRVSTFSGRSPPAPPPYKAPRLDEDGEASEDT 2310
Score = 41.2 bits (95), Expect = 0.008
Identities = 46/150 (30%), Positives = 59/150 (39%), Gaps = 22/150 (14%)
Query: 925 GSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQ--GSPLPHSPVFPPPPPEALIPF 982
G P PP P PP P + + PP P+ G P P PPPPP L+
Sbjct: 2208 GEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPP--PPPPPLTLVLS 2265
Query: 983 CSPPDWCLSPPRPAL--SPILPDSPVSLPLPPPLLPSSEPPPAPPLDP--KFMKDTRPPF 1038
P SPPR A+ + S S P PPP AP LD + +DT P
Sbjct: 2266 SGP----ASPPRQAIRVKRVSTFSGRSPPAPPPY-------KAPRLDEDGEASEDT-PQV 2313
Query: 1039 TNSGQPESSRGSLRPPSTKE--ETSRPPMP 1066
G SR ++ P+ + + RP P
Sbjct: 2314 PGLGSGGFSRVRMKTPTVRGVLDLDRPGEP 2343
Score = 39.7 bits (91), Expect = 0.024
Identities = 48/149 (32%), Positives = 58/149 (38%), Gaps = 26/149 (17%)
Query: 912 EGSGTMKKLDPAV--GSPPAPPPPP---------VPS-PPFPCPADRSPFLPPPPPVTDC 959
E ++ LDP + S APPP P VP+ P P F P P P +
Sbjct: 1833 ERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPS 1892
Query: 960 SQGSPLPH--SPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPP---- 1013
S +P P FP PP + P P PP SP L SP L +PPP
Sbjct: 1893 SLTHHIPTVGDPDFPAPPRRSRRPSPLAPR---PPPSRWASPPLKTSP-QLRVPPPTSVV 1948
Query: 1014 --LLPSSE--PPPAPPLDPKFMKDTRPPF 1038
L P+S PP P P +D P F
Sbjct: 1949 TALTPTSGELAPPGPAPSPPPPEDLGPDF 1977
Score = 39.3 bits (90), Expect = 0.031
Identities = 88/391 (22%), Positives = 131/391 (33%), Gaps = 74/391 (18%)
Query: 840 EKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSIS 899
+ S SP+S Y + P + P S +P + + V + S +V
Sbjct: 2022 DSSEEESSPTSRYI---HFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQ-- 2076
Query: 900 SSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPS------------PPFPCPADRS 947
T G G ++ A PP +PS P R
Sbjct: 2077 ---QPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPRE 2133
Query: 948 PFLPPPPPVTDCSQGSP-LPHSPVFP-------PPPPEALIPFCSPPDWCLSPPRPALSP 999
LPP PP+ + SQ S L SP P P P + P PP+PA S
Sbjct: 2134 ESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAP---EPPKPATSK 2190
Query: 1000 ILPDSPVSL----------PLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRG 1049
I+ + + P+PPP+ +PP P + P T P T+ P
Sbjct: 2191 IILVNKLGQVFVKMAGEGEPVPPPV---KQPPLPPTISP-----TAP--TSWTLPPGPLL 2240
Query: 1050 SLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYH 1109
+ P + PP P T L P R +A ++ + R+P AP +
Sbjct: 2241 GVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPR-----QAIRVKRVSTFSGRSPPAPPPY 2295
Query: 1110 LKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSS-SQGDHGSAAERGGPVSRSPGAPS 1168
P ++ + + + T +P S+ + RG PG P
Sbjct: 2296 KAP-----------RLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEP- 2343
Query: 1169 AGEAEARPSPSTT---PLPDSSPSRKP--PP 1194
AGE P + PLP+ P + P PP
Sbjct: 2344 AGEESPGPLQERSPLLPLPEDGPPQVPDGPP 2374
Score = 33.1 bits (74), Expect = 2.2
Identities = 69/281 (24%), Positives = 96/281 (34%), Gaps = 50/281 (17%)
Query: 1151 GSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKP------PPISKKPKLFLV 1204
G G P S + P+ G+ + P + P R P PP+ P+L V
Sbjct: 1883 GPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQL-RV 1941
Query: 1205 VPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSRE---AKESSAAQAGSHATHPGT- 1260
PP A+ P PSP E+ + SAA A+ GT
Sbjct: 1942 PPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTE 2001
Query: 1261 ----SVLEGGAAGS------------MSPSR-------VEANVPMVQPDVSP-APKQEEP 1296
++ GA GS SP+ + P + P +P AP+ E+
Sbjct: 2002 PFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQ- 2060
Query: 1297 AENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDL 1356
+ D G D E+ QQ G P +G L G+ R R EDL
Sbjct: 2061 -LDGVDDGTDSEAEAVQQPRGQGTP---PSGPGVVRAGVLGAAGD-------RARPPEDL 2109
Query: 1357 FAAIHRSKRKVLGRRDSDDDHSRNHS--PSPPVTPTGAAPS 1395
+ I K LG R S P+PP+ G+ PS
Sbjct: 2110 PSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLA-NGSQPS 2149
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 81.6 bits (200), Expect = 5e-15
Identities = 95/331 (28%), Positives = 126/331 (38%), Gaps = 75/331 (22%)
Query: 796 PAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQ 855
PAG + G TG GP GSRA P++P ++ ++ P SP G +S+
Sbjct: 111 PAGQRDVAGG-KTGQGP------GSRAPSPRLPNKTISGPLIPPA------SPRLGNTSE 157
Query: 856 SNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSG 915
++ P + + P P P P SS S T L S G
Sbjct: 158 AHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSS-------SPIKTPLVSPPGPLTKG 210
Query: 916 TMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCS---QGSPLPHSPVFP 972
+ P V APP P P PP P P P LPP ++D + Q +PL H P P
Sbjct: 211 NL----PVV----APPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPL-HLPPIP 261
Query: 973 PPPPEALIPFCSPPDWCLSP------------PRPALSPILPDSP-VSLPLPPPLLP--- 1016
PP P L+P C P P P P L P SP SLP PP LP
Sbjct: 262 PPLP--LLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPP--LPGVN 317
Query: 1017 --SSEPPPAPPLDPKFMKDTR------------PPFT-------NSGQPESSRGSLRPPS 1055
S PPP PP P F + PP + G+P + G L PP
Sbjct: 318 SSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPP 377
Query: 1056 TKEETSRPPMPLITTEALQMVQLRPVRKNSG 1086
+R P +++++ Q P ++ G
Sbjct: 378 A--PPARSPTTELSSKSQQATAWTPTQQPGG 406
Score = 63.2 bits (152), Expect = 2e-09
Identities = 92/383 (24%), Positives = 131/383 (34%), Gaps = 135/383 (35%)
Query: 877 GKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVP 936
G P P++P + IS I +S L +++ G+ APP P VP
Sbjct: 127 GSRAPSPRLPNKT---ISGPLIPPASPRLGNTSEAHGAART-----------APPRPNVP 172
Query: 937 SPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPA 996
+PP P P PPPPP P PPP +P SP P
Sbjct: 173 APPPPTP-------PPPPP----------------PLPPP---LPSSSPIK------TPL 200
Query: 997 LSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPST 1056
+SP P + +LP+ P +P + PPP PP P T PP
Sbjct: 201 VSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPP-----TPPPL------------------ 237
Query: 1057 KEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFL 1116
PP +++ +A++ QL P+ P+ P L P
Sbjct: 238 ------PPASVLSDKAVKP-QLAPLHL------------------PPIPPPLPLLPPCGY 272
Query: 1117 KSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARP 1176
+++PAS PA+ + + P + P P R
Sbjct: 273 PGL--------KAEPAS-------PAQDAQE-----------PPAPPPPLPPYASCSPRA 306
Query: 1177 SPSTTPLPD-SSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEE 1235
S PLP +S S PPP+ PP F P + ++AL A P+P
Sbjct: 307 SLPAPPLPGVNSSSETPPPL----------PPKSPSFQAPPQKAGAQALPAPPAP----P 352
Query: 1236 GSVHSREAKESSAAQAGSHATHP 1258
GS + K AG +P
Sbjct: 353 GSQPFLQKKRHGRPGAGGGKLNP 375
Score = 43.5 bits (101), Expect = 0.002
Identities = 59/214 (27%), Positives = 76/214 (35%), Gaps = 16/214 (7%)
Query: 999 PILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKE 1058
P+ P P LP PPP P PPP PP P DT P+ R +L +
Sbjct: 2 PVPPPPPPPLPPPPP--PLGAPPPPPPSAPPVSTDTSS--LRRADPK-GRSALLADIQQG 56
Query: 1059 ETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYH-LKPSAFLK 1117
R + A Q+ + K G A T A + L+P+
Sbjct: 57 TRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA---- 112
Query: 1118 SRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPS 1177
+ ++ P S S P K+ S A+ R G S + GA A A RP+
Sbjct: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGA--ARTAPPRPN 170
Query: 1178 ----PSTTPLPDSSPSRKPPPISKKPKLFLVVPP 1207
P TP P P P P S K LV PP
Sbjct: 171 VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP 204
Score = 38.9 bits (89), Expect = 0.040
Identities = 72/285 (25%), Positives = 97/285 (34%), Gaps = 73/285 (25%)
Query: 928 PAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPD 987
P PPPPP P P PPPPP+ G+P PPPPP A P S
Sbjct: 2 PVPPPPPPPLP------------PPPPPL-----GAP-------PPPPPSA--PPVSTDT 35
Query: 988 WCLSPPRP-ALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPES 1046
L P S +L D L + P ++ ++ G +
Sbjct: 36 SSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQ-------IESSKGTNKEGGGSAN 88
Query: 1047 SRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAP 1106
+RG+ PP T + P+ LRP +R +T P
Sbjct: 89 TRGASTPP-TLGDLFAGGFPV----------LRPA-----------GQRDVAGGKTGQGP 126
Query: 1107 QYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGA 1166
PS L ++ + + PAS P ++ HG+A R P + A
Sbjct: 127 GSR-APSPRLPNKTISGPL---IPPAS-------PRLGNTSEAHGAA--RTAPPRPNVPA 173
Query: 1167 PSAGEAEARPSPSTTPLPDSSPSR----KPPPISKKPKLFLVVPP 1207
P P P PLP SSP + PP K L +V PP
Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPP 218
Score = 34.7 bits (78), Expect = 0.76
Identities = 15/29 (51%), Positives = 15/29 (51%), Gaps = 7/29 (24%)
Query: 927 PPAPPPPPVPSPPFPCPADRSPFLPPPPP 955
PP PPP P P PP P PPPPP
Sbjct: 5 PPPPPPLPPPPPPLGAP-------PPPPP 26
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 80.5 bits (197), Expect = 1e-14
Identities = 64/174 (36%), Positives = 72/174 (41%), Gaps = 38/174 (21%)
Query: 922 PAVGSPPAPPPP-PVPSPPFPCPADRSPFLPPPPPVTDCSQG------SPLPHSPVFPPP 974
P PP PPPP V PP P +R PPPPV Q PLP P PPP
Sbjct: 244 PGPPGPPGPPPPGQVLPPPLAGPPNRGD--RPPPPVLFPGQPFGQPPLGPLPPGP--PPP 299
Query: 975 PPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPL---PPPLLPS---SEPPPAPPLDP 1028
P P PP PP P P P P+ PL PPP LP PPPAP ++P
Sbjct: 300 VPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNP 359
Query: 1029 KFMKDTRPPFTNSGQPESS-----------------RGSLRPPSTKEETSRPPM 1065
F PP TNSG P S RG PP + +T+R P+
Sbjct: 360 AFF----PPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPL 409
Score = 67.8 bits (164), Expect = 8e-11
Identities = 67/196 (34%), Positives = 73/196 (37%), Gaps = 54/196 (27%)
Query: 913 GSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFP 972
G G P P P P P PPFP A ++P PP P P P V P
Sbjct: 203 GRGRFPGAVPGGDRFPGPAGPGGPPPPFP--AGQTPPRPPLGPPGPPGPPGPPPPGQVLP 260
Query: 973 P-----------PPPEALI---PFCSPPDWCL-----------------------SPPRP 995
P PPP L PF PP L PP P
Sbjct: 261 PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPP 320
Query: 996 ALSPILPDSPVSLPL---PPPLLPS---SEPPPAPPLDPKFMKDTRPPFTNSGQPES-SR 1048
P P P+ PL PPP LP PPPAP ++P F PP TNSG P S SR
Sbjct: 321 GPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFF----PPPTNSGMPTSDSR 376
Query: 1049 GSLRPPSTKEETSRPP 1064
G PP T + RPP
Sbjct: 377 G---PPPT-DPYGRPP 388
Score = 32.0 bits (71), Expect = 5.0
Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 10/86 (11%)
Query: 1158 GPVSRSPG---APSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAV 1214
GP PG P + P P P P P PP++ P L PPP A
Sbjct: 295 GPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPG---AP 351
Query: 1215 EPAENVSEALRAVPS----PTTGEEG 1236
PA +V+ A P+ PT+ G
Sbjct: 352 PPAPHVNPAFFPPPTNSGMPTSDSRG 377
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 80.1 bits (196), Expect = 2e-14
Identities = 158/684 (23%), Positives = 235/684 (34%), Gaps = 141/684 (20%)
Query: 702 ATLQHSLQLSLPGKSGSSPSQSPCSDL------EEPWLPRSRSQSTVSAGSSMTSATTPN 755
AT+ S + P +S + S++P S E ++ S VS+ + T P
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 756 VYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRH 815
G S +T + + + T+ G + D P + G P+ R
Sbjct: 128 PLGQKGLRISAEETVA-RGKATEAPKRSALSAGARRDTSGP------TPGTPSPAMARRS 180
Query: 816 VQEGSRATMPQ-VPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTA------------- 861
G+ +P+ P +P P KS +S +S +S+ +P A
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKS---VSSASEHSTTEPSPAARRRPSAGGGLQRP 237
Query: 862 --------LTPVPVFLKSVSPANGK-------GKPKPK----------VPERKSSLISSV 896
TP+ +S A G +PKPK P RK + +
Sbjct: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
Query: 897 SISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPP--- 953
+SSS + S + T+ + A P PP P + P P A SP PP
Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPL-APPSPSAPPSLQT 356
Query: 954 ---PPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLS-----PPRP-ALSPILPDS 1004
PP T SQ P +P PP IP P S PP P ALS + +
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416
Query: 1005 PVSLP-------------------LPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPE 1045
+ P L P P+S PP +PPL PP S P
Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSP- 475
Query: 1046 SSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVA 1105
++ P S+ P+ + +AL + S + A LS P+
Sbjct: 476 ----AVSPLSS-------PLTIHPLQALSSLA-------SHSPQAPLSSLI----MPPLE 513
Query: 1106 PQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPG 1165
Q L P + S E+ P S P P +++S A P +P
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLP----SLAPPPLQTAS-------APLTTPHLETPP 562
Query: 1166 APSAGEAEARPSPSTTPLPD-----SSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAEN- 1219
P+ +A PSP TTP P+ ++P + PP P L + PP A P +
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP 622
Query: 1220 ---VSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRV 1276
L+A PSP S + + ++ A A +L+ + SP
Sbjct: 623 PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALA--------VHLLQAPFSPPPSPPVQ 674
Query: 1277 EANVPMVQPDVSPA---PKQEEPA 1297
P P VSP+ P Q P+
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPS 698
Score = 79.3 bits (194), Expect = 3e-14
Identities = 208/912 (22%), Positives = 308/912 (33%), Gaps = 139/912 (15%)
Query: 414 PNATLSSSSEVIAIPTAQSAGQRESKSSGSSHARIKSRDHLI--------SRHAVKGDPQ 465
P ++SS+SE + +A +R S G +S S + +G P+
Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Query: 466 SPGRHWNEGHATILS-----QDLDPHSPGEPALLSLCDSAVPLNAPANRENGSQAMPYNC 520
+P H ++ L Q P PAL L S PL P+ +G++A P
Sbjct: 265 APA-HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS--PLATPS--PSGTKARPVPP 319
Query: 521 RNNLAFPAHPQDVDGKSESSYSGGGGHSSSEPWEYKSSGNGRASP---LKPHLATPGYST 577
+N A P ++ S S P ++ + A+P P + TP
Sbjct: 320 PDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA 379
Query: 578 PTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGNLCNSSDGFGNPRHSVI 637
P S + + Q + + SL + +S+ + GS L HS +
Sbjct: 380 PPS-LQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL--------QATHSFL 430
Query: 638 NVFVGRAQKNQGDRSNYQDKSLSRNISLKKAKKPPLPPSRTD-SLRRIPKKSSQCNGQVL 696
+ S Q ++ + S + P PP + SL P + + V
Sbjct: 431 TM------------SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478
Query: 697 NESLIATLQHSLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSSMTSATTPNV 756
S T+ H LQ +L + SP Q+P S L P L S + S + S TTP +
Sbjct: 479 PLSSPLTI-HPLQ-ALSSLASHSP-QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL 535
Query: 757 YSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHV 816
+L P T+S T E P PA C + P
Sbjct: 536 ENLPSLAPPPLQTASAPLT-----------TPHLETPPCPAP-CPLQAPPSPLTTPPPET 583
Query: 817 QEGSRATMPQVPGGSVKPKIM---SPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVS 873
PQ P P + SP S P + P P P +S
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643
Query: 874 PANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPP 933
P P P+ P + V + + S S + + P SP A PP
Sbjct: 644 PL---ATPSPQAPNALA-----VHLLQAPFSPPPSPPVQAPFSPPASPPV--SPSATPPS 693
Query: 934 PVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPP 993
P P P + P PP P P SP PPP+A P +PP PP
Sbjct: 694 QAP-PSLAAPPLQVPPSPPASP----------PMSP-SATPPPQAPPPLAAPP--LQVPP 739
Query: 994 RPALSPILPDSPVSLPLPPPLL--PSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSL 1051
P SP + S P PPLL P + PP+PP +P
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP--------------- 784
Query: 1052 RPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLK 1111
PP + PP+ + + P ++ + L+ Q AP +
Sbjct: 785 -PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843
Query: 1112 PSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSS-QGDHGSAAERGG---PVSRSPGAP 1167
PS ++ +++ +P PTP +S G + A G P SRSP +
Sbjct: 844 PSP-----PASPTLQAPRRP-------PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891
Query: 1168 SAGEAEARPSPSTTPLP------DSSP----SRKPPPISK----KPKLFLVVPPPQKDFA 1213
+G A S S T P DS P + PPP ++ P + P P F
Sbjct: 892 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 951
Query: 1214 VEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGS--HATHPGTS---VLEGGAA 1268
P + P G +++ E ES+ G+ PGTS G A
Sbjct: 952 GAPGAPLPWPPATGPGSADG-LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA 1010
Query: 1269 GSMSPSRVEANV 1280
G+ S S +A +
Sbjct: 1011 GASSRSPKQARL 1022
Score = 49.7 bits (117), Expect = 2e-05
Identities = 94/379 (24%), Positives = 130/379 (34%), Gaps = 48/379 (12%)
Query: 943 PADRSP-FLPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPI- 1000
PA R+P L P PP GSP P PP P AL + P I
Sbjct: 17 PAARAPGLLTPRPP------GSPRPP----PPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 1001 ---LPDS-PVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPST 1056
+P+S P + P S P PP + + PP N +S G + P
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGR--GERAPPAKN-----TSPGPVSSPGR 119
Query: 1057 KEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQR-----TPVAPQYHLK 1111
T+RP + + L++ V + EA + S +A +R TP P
Sbjct: 120 ASGTTRPGP--LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP----S 173
Query: 1112 PSAFLKSRNSTNEMESESQPASVTSSLPT--PAKSSSQGDHGSAAERGGPVSRSPGAPSA 1169
P+ +SR + E+ S PT P KS S S E R P A
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233
Query: 1170 GEAEARPSPSTTPLPDSSPSRKPP-----------PISKKPKLFLVVPPPQKDFAVEPAE 1218
+ A S S++ P SSP+R P P KPK + PPQ + A
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293
Query: 1219 NVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEA 1278
L + P T G+ +AA P + SPS +
Sbjct: 294 PALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353
Query: 1279 NVPMVQPDVSPAPKQEEPA 1297
+ P +P P Q P+
Sbjct: 354 LQTLPSPPATP-PSQAPPS 371
Score = 41.6 bits (96), Expect = 0.006
Identities = 93/376 (24%), Positives = 125/376 (33%), Gaps = 78/376 (20%)
Query: 920 LDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPEA- 978
L P P PPPP P+ A + P G+ +P S P A
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
Query: 979 ---LIPFCSPP---DWCLSPPRPALSPILPDSPVSLP-------LPPPL----------- 1014
P PP +PP SP PVS P P PL
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSP----GPVSSPGRASGTTRPGPLGQKGLRISAEE 140
Query: 1015 ----LPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRP-----PM 1065
++E P L +DT P + P +R S R T+ RP P
Sbjct: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS-RAAGTEVGLPRPAPSARPR 199
Query: 1066 PLI--------------TTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLK 1111
P TTE + RP ++G + + R+ TP++
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRP---SAGGGLQRPASRSLSSSATPLSSPARSG 256
Query: 1112 PSAFLKSRNSTNEMESESQP-ASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSP-GAPSA 1169
PSA R + SQP +L P + + D AA GP+S SP PS
Sbjct: 257 PSA----RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD---AAPALGPLSSSPLATPSP 309
Query: 1170 GEAEARPSP----STTPLPDSSPSR---------KPPPISKKPKLFLVVPPPQKDFAVEP 1216
+ARP P + TPLP + P PP S P L + PP + P
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Query: 1217 AENVSEALRAVPSPTT 1232
+ ++A PS T
Sbjct: 370 PSMTTPPMQAPPSLQT 385
Score = 41.2 bits (95), Expect = 0.008
Identities = 91/400 (22%), Positives = 140/400 (35%), Gaps = 55/400 (13%)
Query: 1156 RGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVV---------P 1206
+ G +R+P A + G TP P SP R PPP++ P V+ P
Sbjct: 9 KAGAAARTPAARAPG--------LLTPRPPGSP-RPPPPVT--PAALRVLGAAGAVGRKP 57
Query: 1207 PPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHA-----THPGTS 1261
++ + A A RA P T G+ A A+ G A T PG
Sbjct: 58 LAERAGGIGGATIPESAPRAGP---TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPV 114
Query: 1262 VLEGGAAGSMSPS-------RVEANVPMVQPDVSPAPKQEEPA-----ENSADTGGDGES 1309
G A+G+ P R+ A + + + APK+ + + S T G
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
Query: 1310 CLSQQDGAAGVPETNAAGSSSEACDFLKEDGNDEVMTPSRPRTTEDLFAAIHRSKRKVLG 1369
++++ AAG + S E V + S TTE AA R + G
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA--RRRPSAGG 232
Query: 1370 RRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQVGSIQRSIRKSSTSSDNFKALLLKKGS- 1428
S + S +P +P + PS G+ + S +AL + +
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSAR-----GTPRAPAHPSQPKPKGLQALRPPQVTP 287
Query: 1429 -RSDTSARMS--AAEMLKNTDPRFQRSRSEPSPD--APESPSSCSPSKNRRAQEEWAKNE 1483
R D + + ++ L P ++R P PD A P++ PS A
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS 347
Query: 1484 GLMPRSLSF--SGPRYGRSRTPPSAASSRYSMRNRIQSSP 1521
P SL S P S+ PPS + +Q+ P
Sbjct: 348 PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo
sapiens]
Length = 1125
Score = 80.1 bits (196), Expect = 2e-14
Identities = 87/315 (27%), Positives = 110/315 (34%), Gaps = 50/315 (15%)
Query: 928 PAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHS---PVFPPP---PPEALIP 981
P P P PVP PP P PA P PPP V G P+ + P F PP PP P
Sbjct: 657 PIPKPLPVPVPPIPVPA---PITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGP 713
Query: 982 FCSPPDWCLSPPRPALSPILPDSPVSLPL-------PPPLLP--SSEPPPAPPLD-PKFM 1031
PP PP P L P +P+ LP PPP+ P S PP PP+ P +
Sbjct: 714 GVPPPP----PPPPFLRPGF--NPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLV 767
Query: 1032 KDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPL-ITTEALQMVQLRPVRKNSGAEAA 1090
R SG GS PP+ PP+ ++ Q V PV
Sbjct: 768 SGARGN-AESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTG 826
Query: 1091 QLSERTA--QEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTS-SLPTP------ 1141
L R QR P P HL+ + R M P ++P P
Sbjct: 827 LLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGP 886
Query: 1142 --------AKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSS------ 1187
G G GGP R + + +P P P
Sbjct: 887 FPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPP 946
Query: 1188 PSRKPPPISKKPKLF 1202
PS++PPP ++P+ F
Sbjct: 947 PSQQPPPTQQQPQQF 961
Score = 48.1 bits (113), Expect = 7e-05
Identities = 92/409 (22%), Positives = 135/409 (33%), Gaps = 70/409 (17%)
Query: 825 PQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPK 884
P P S+ P P ++S + G + ++ V ++ +V PA P P
Sbjct: 746 PITPPVSIPPPHTPPISIPNLVSGARGNAESGDS------VKMYGSAVPPAAPTNLPTPP 799
Query: 885 VPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPP--------PPVP 936
V + SL+ + ++ + ST G L P P PPP PP P
Sbjct: 800 VTQ-PVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRP 858
Query: 937 SPPF-----PCPADRSPFLPPPPPVTDCSQGSPLPHSP-VFP------------PPPPEA 978
PP P P +PPP + +G PH P V P P PE
Sbjct: 859 MPPHMMHRGPPPGPGGFAMPPPHGM----KGPFPPHGPFVRPGGMPGLGGPGPGPGGPED 914
Query: 979 LIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPF 1038
PP P+P P P P PS +PPP +F D R F
Sbjct: 915 RDGRQQPPQQPQQQPQPQA----PQQPQQQQQQQPP-PSQQPPPTQQQPQQFRNDNRQQF 969
Query: 1039 TNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQ 1098
NSG+ + R R + E R + R NS + + R+
Sbjct: 970 -NSGR-DQERFGRRSFGNRVENDRE----------RYGNRNDDRDNSNRDRREWGRRSPD 1017
Query: 1099 EQRTPVAPQYHLKPSAF---------LKSRNSTNEMESESQP-----ASVTSSLPTPAKS 1144
R + + + S +SR E + +P A ++ P
Sbjct: 1018 RDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQ 1077
Query: 1145 SSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPP 1193
D S E+G VS + + E A + S P DS + + P
Sbjct: 1078 VGNVDTASELEKG--VSEAAVLKPSEELPAEATSSVEPEKDSGSAAEAP 1124
Score = 33.1 bits (74), Expect = 2.2
Identities = 67/293 (22%), Positives = 102/293 (34%), Gaps = 66/293 (22%)
Query: 918 KKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPPE 977
KK D + AP P+P PA +P PPPP+
Sbjct: 278 KKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAA--------------------SPPPPQ 317
Query: 978 ALIPFCSPPDWCLSPP----------RPALSPILPDSPV--SLPLPP-------PLLPSS 1018
A PF P D P +P + I D P+ +PLPP LLP+
Sbjct: 318 A--PFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQD-PMHHQVPLPPNGQMPGFGLLPT- 373
Query: 1019 EPPPAPPLDPKFMKDTRP---PFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQM 1075
PP PP+ + T P PF S Q ++ + +P + E +P + +
Sbjct: 374 --PPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDN 431
Query: 1076 VQLR-------PVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMES- 1127
+ R P R+ S + + R + + + H S + R+ E E
Sbjct: 432 RKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERR 491
Query: 1128 -------ESQPASVTSS---LPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAG 1170
+ + ASV S+ + K ++Q D S E GP+ P G
Sbjct: 492 QKGLPQVKPETASVCSTTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPRG 544
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 79.0 bits (193), Expect = 4e-14
Identities = 105/443 (23%), Positives = 152/443 (34%), Gaps = 53/443 (11%)
Query: 915 GTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPP 974
G M P V PPP P PP P+ P +PP P T G P PV PP
Sbjct: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMP---PPVMPPS 568
Query: 975 PPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLP-LPPPLLPSSEPPPAPPLDPKFMKD 1033
P ++ P PP + P P L P S P LPPP L S+ PPP PL P
Sbjct: 569 LPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSAT 628
Query: 1034 TRPPFTNSGQPESSRGSLR----PPSTKEETSR---PPMPLITTEALQMVQLRPVRKNSG 1086
P G P+ L PP++ ++S+ P P + + P +
Sbjct: 629 PPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPP 688
Query: 1087 AEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSS 1146
++A SE+ + P++ + L S+F + + SQP + +P
Sbjct: 689 LQSAGPSEQV--NSKAPLS-KSALPYSSFSSDQGLGESSAAPSQPITAVKDMPV------ 739
Query: 1147 QGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVP 1206
R G + P S E+ P + SR P K P+ P
Sbjct: 740 ---------RSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRP 790
Query: 1207 P-PQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEG 1265
P+ + PAE +P G + + S Q+G P
Sbjct: 791 DGPRPRYEGHPAEGTKSKWGMIP---RGPASQFYITPSTSLSPRQSGPQWKGP------- 840
Query: 1266 GAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDG----AAGVP 1321
P+ + + + P +EP ADT + + Q AA V
Sbjct: 841 ------KPAFGQQHQQQPKSQAEPLSGNKEPL---ADTSSNQQKNFKMQSAAFSIAADVK 891
Query: 1322 ETNAAGSSSEACDFLKEDGNDEV 1344
+ AA S+ D +E EV
Sbjct: 892 DVKAAQSNENLSDSQQEPPKSEV 914
Score = 61.2 bits (147), Expect = 8e-09
Identities = 98/385 (25%), Positives = 122/385 (31%), Gaps = 61/385 (15%)
Query: 851 GYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTS 910
G SS P P PV L SP G G P SS S +S L+
Sbjct: 9 GGSSHYPPPPVPPPPPVALPEASP--GPGYSSSTTPAAPSS---SGFMSFREQHLAQLQQ 63
Query: 911 TEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVT------------- 957
+ +K V P PPPP+P PP + PPPPP+
Sbjct: 64 LQQMH--QKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQ 121
Query: 958 --------DCSQGSP------LPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPD 1003
G P L P PP PP + +P P + PP+P S P
Sbjct: 122 QYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMP---PSQSYMPPPQPPPSYYPPT 178
Query: 1004 SPVSLPLPPPLLPS-SEPPP-----APPLDPKFMKDTRPPFTNSGQ---PESSRGSLRPP 1054
S S P PP PS S+ PP AP + + + Q P S RP
Sbjct: 179 S--SQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPS 236
Query: 1055 S--TKEETSRPPMPLITTEALQMVQLRPVR---KNSGAEAAQLSERTAQEQRTPVAPQYH 1109
+K + PP P VQ P+ KN E Q + TP Q +
Sbjct: 237 QGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQY 296
Query: 1110 LKPSAFLKSRNSTN-EMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPS 1168
L + T + + V P P K S P S P P
Sbjct: 297 WYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPE-SPSSEEPPLPP 355
Query: 1169 AGEAEARPSPSTTPLPDSSPSRKPP 1193
E E P PLP P + P
Sbjct: 356 PNE-EVPP-----PLPPEEPQSEDP 374
Score = 57.0 bits (136), Expect = 1e-07
Identities = 62/225 (27%), Positives = 83/225 (36%), Gaps = 28/225 (12%)
Query: 854 SQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEG 913
SQ P P PV S+ P P +P + + + S TS
Sbjct: 524 SQMPPPLPTMPPPVLPPSLPP--------PVMPPALPATVPPPGMPPPVMPPSLPTSVPP 575
Query: 914 SGTMKKLDPAVGSPPAPPP---PPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPV 970
G L A P PPP P P P P+ S PP P+ S +P P P
Sbjct: 576 PGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIP- 634
Query: 971 FPPPPPEALIPFCSPPDWCLSPPRPA---LSPILPDSPVSLPLPPPLLPSSEPPPA--PP 1025
PP P+ + PP +P PA S +P+ P LP P+ S PP PP
Sbjct: 635 -PPGVPQGI-----PPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPP 688
Query: 1026 LD---PKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPL 1067
L P +++ P + S P SS S E ++ P P+
Sbjct: 689 LQSAGPSEQVNSKAPLSKSALPYSSFSS--DQGLGESSAAPSQPI 731
Score = 47.4 bits (111), Expect = 1e-04
Identities = 84/355 (23%), Positives = 116/355 (32%), Gaps = 131/355 (36%)
Query: 922 PAVGSPP-------APPP--------PPVPSPPFPCPADRSPFLPPPPPV---------- 956
P +G PP APP PPVP PP P P P LPPPPPV
Sbjct: 1516 PPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP----PPLPPPPPVIKPQTSAVEQ 1571
Query: 957 -------------TDCSQG---------SPLPHSPVFPPPPPEALIPFCSPPDWCLSPPR 994
T+ QG + +P +PV PPPP + IP PP
Sbjct: 1572 ERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIP----------PPG 1621
Query: 995 PALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPP 1054
P P+ +P P S+PPP Q G R
Sbjct: 1622 PV--------PMGMP------PMSKPPPV-------------------QQTVDYGHGRDI 1648
Query: 1055 STKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSA 1114
ST + P IT ++ P+ + S E +R ++ P + + +
Sbjct: 1649 STNKVEQIPYGERIT------LRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNV 1702
Query: 1115 FLKSRNSTNEMESE------------SQPASVTSSLPTPAKSSSQGD--HGSAAERGG-- 1158
R+ + E+ + P ++ S D S++ RGG
Sbjct: 1703 IADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGFD 1762
Query: 1159 ----------PVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPP---ISKKPK 1200
PV P + GE P PLP S S +PPP + KKP+
Sbjct: 1763 RPSYDRKSDRPVYEGP-SMFGGERRTYPE-ERMPLPAPSLSHQPPPAPRVEKKPE 1815
Score = 44.3 bits (103), Expect = 0.001
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 7/131 (5%)
Query: 828 PGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPE 887
P GS +P + ++ PS+ ++S+ P PVP+ P P P +
Sbjct: 1508 PPGSYRPPPPMGKPPGSIVRPSAP-PARSSVPVTRPPVPI--PPPPPPPPLPPPPPVIKP 1564
Query: 888 RKSSLISSVSISSSSTSLSSSTSTEG-SGTMKKLDPAVGSPPAPPPPPVPS---PPFPCP 943
+ S++ S L + +G + K A+ S P PPPPV S PP P P
Sbjct: 1565 QTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVP 1624
Query: 944 ADRSPFLPPPP 954
P PPP
Sbjct: 1625 MGMPPMSKPPP 1635
Score = 41.6 bits (96), Expect = 0.006
Identities = 107/490 (21%), Positives = 161/490 (32%), Gaps = 91/490 (18%)
Query: 853 SSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTE 912
S S P + P+P + P G P P VP+ +++ + +S+S SS +
Sbjct: 609 SLSSTAPPPVMPLPPLSSATPPP---GIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEK 665
Query: 913 GSGTMKKLDPAVGS-PPAPPPPPVPSP-PFPCPADRSPFLPPPPPVTDCSQGSPLPHSPV 970
+ + GS PP PP+ S P ++P P + S L S
Sbjct: 666 PRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSA 725
Query: 971 FPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLD-PK 1029
P P A+ P R +LPD P S L E P P D P+
Sbjct: 726 APSQPITAVKDM---------PVRS--GGLLPDPPRSSYL--------ESPRGPRFDGPR 766
Query: 1030 FMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEA 1089
+D S RP + E +RP P RP + G A
Sbjct: 767 RFEDL----------GSRCEGPRPKGPRFEGNRPDGP------------RP--RYEGHPA 802
Query: 1090 AQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNE---------MESESQPASVTSSLPT 1140
+ R P A Q+++ PS L R S + + + QP S + P
Sbjct: 803 EGTKSKWGMIPRGP-ASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKS--QAEPL 859
Query: 1141 PAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPK 1200
D S ++ + + + +A + + + S L DS +S+ P
Sbjct: 860 SGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGP- 918
Query: 1201 LFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGT 1260
V P D V+ E + +AV P V ++ S T
Sbjct: 919 ----VEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPSK------------T 962
Query: 1261 SVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQEEPAENSADTGGDGESCLSQQDGAAGV 1320
+EGG A + S + D P +EN+ D G L + D
Sbjct: 963 GGMEGGTAVATSSLTAD-------NDFKPVGIGLPHSENNQDKG------LPRPDNRDNR 1009
Query: 1321 PETNAAGSSS 1330
E N SSS
Sbjct: 1010 LEGNRGNSSS 1019
Score = 39.3 bits (90), Expect = 0.031
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 7/64 (10%)
Query: 970 VFPPP----PPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPP 1025
++PPP PP P PP + P P +P + +P+PPP P PPP P
Sbjct: 1505 MYPPPGSYRPPP---PMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPV 1561
Query: 1026 LDPK 1029
+ P+
Sbjct: 1562 IKPQ 1565
Score = 38.5 bits (88), Expect = 0.053
Identities = 57/230 (24%), Positives = 81/230 (35%), Gaps = 34/230 (14%)
Query: 825 PQVPGGSVKPKIMSPEKSHRVI-SPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKP 883
P VP GS P P +S+ P Y +++ L P P+ P P
Sbjct: 150 PPVPPGSYMP----PSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTP 205
Query: 884 KVPERKSSLISSVSISSS---STSLSSSTSTEGSGTMKKLDPAVGSPPAPPP-------- 932
SS S +S S S S+ S S ++G + L P PP+ PP
Sbjct: 206 SYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPP---PPSAPPGNKTTVQQ 262
Query: 933 PPVPSPPFPCPADRSPFLPPPPPVTDCSQG-----------SPLPHSPVFPPPPPEALIP 981
P+ S ++ P P P T Q S + V P + +
Sbjct: 263 EPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVV 322
Query: 982 FCSPPDWCLSPPRPALSPILPDSPVS--LPLPPPLLPSSEPPPAPPLDPK 1029
P+ + +P+SP S PLPPP PPP PP +P+
Sbjct: 323 AKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPP--NEEVPPPLPPEEPQ 370
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 78.6 bits (192), Expect = 5e-14
Identities = 194/847 (22%), Positives = 294/847 (34%), Gaps = 183/847 (21%)
Query: 845 VISPSSGYSSQ---SNTPTALTPVPVFLKSVSPANG----KGKPKPKVPERKSSLISSVS 897
V++P SG S S P + +F VS A G + +P P P ++++ V+
Sbjct: 529 VLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAA-TTVLQGVT 587
Query: 898 ISSSSTSLSSST------STEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPC-----PADR 946
+ S+ ++ ++ +T + T + P + PAP PP S P P A +
Sbjct: 588 LPPSAVAMLNTPDGLVQPATPAAATGEAA-PVLTVQPAPQAPPAVSTPLPLGLQQPQAQQ 646
Query: 947 SPFLPPP----PPVTDCSQGSP----LPHSPVFPPPP----------------------- 975
P P P PP Q SP P V PP
Sbjct: 647 PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ 706
Query: 976 ------------PEALIPFCSPPDWCLSPPRP-----ALSPILPDSPVSLPLPPPLLPSS 1018
P ++I PP +P P L P PDS S P P P +P++
Sbjct: 707 QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQAS-PAPAPQIPAA 765
Query: 1019 EPPPAPPLDPKFMKDTRPPFTNS---GQPESSRGSLRPPSTKEETSRPPM--PL------ 1067
P P + P +S P +R RPPS + SRPP PL
Sbjct: 766 APLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPP 825
Query: 1068 ---ITTEALQMVQ----LRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRN 1120
T + ++Q + P N A + + Q P P+ L P+ L +
Sbjct: 826 QAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQP--PEGPLPPAPHLPPSS 883
Query: 1121 STNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPST 1180
+++ + S S+ +S LP P S Q P S+ P P P+
Sbjct: 884 TSSAVASSSE---TSSRLPAPTPSDFQLQF--------PPSQGP------HKSPTPPPTL 926
Query: 1181 TPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHS 1240
+P+ P+ PPP P+ F +V P A+ + + E VPS G +
Sbjct: 927 HLVPE--PAAPPPP---PPRTFQMVTTPFP--ALPQPKALLERFHQVPS------GIILQ 973
Query: 1241 REAKESSAAQAGSHA----THPGTSVLEGGAAGS---MSPSRVEANVPMVQPDVSPAPKQ 1293
+A + AA S + T P SVL G A S +PS A PM + P
Sbjct: 974 NKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPA 1033
Query: 1294 EEPA----------ENSADTGGDGESCLSQQDGAAGVPETNAAGSSSEACDFLK--EDGN 1341
E A +A +G S L + +G+ + S EAC FL+
Sbjct: 1034 ENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEAC-FLEHLHKHQ 1092
Query: 1342 DEVMTPSRPRTTEDLFAAIHRSKRKVLGRRDSDDDHSRNHSPSPPVTPTGAAPSLASPKQ 1401
V+ P A+HR P GA PS + +
Sbjct: 1093 GSVLHPDYKTAFPSFEDALHRL--------------------LPYHVYQGALPSPSDYHK 1132
Query: 1402 VGS-----IQRSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEML----KNTDPRFQRS 1452
V + ++++ + ++ LLL++ R SA M + + + T +
Sbjct: 1133 VDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQ 1192
Query: 1453 RSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGP--------------RYG 1498
++ PD S SS S A E + G P S S G R+G
Sbjct: 1193 LAKEKPDEYVS-SSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHG 1251
Query: 1499 RSRTPPSAASSRYSMRNRIQSSPMTVISEGEGEAVEPVDSIARGALGAAEGCSLDGLARE 1558
+ PS +R S SS + S + + P+ S R + E S GL +
Sbjct: 1252 GAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLK 1311
Query: 1559 EMDEGGL 1565
E GL
Sbjct: 1312 IKQEAGL 1318
Score = 63.9 bits (154), Expect = 1e-09
Identities = 118/472 (25%), Positives = 172/472 (36%), Gaps = 70/472 (14%)
Query: 796 PAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPG--GSVKPKIMSPEKSHRVIS-PSSGY 852
P + S+ +P G +Q+ PQ P + P+ +P+ S + S P
Sbjct: 625 PQAPPAVSTPLPLG------LQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIV 678
Query: 853 SSQ--SNTPTALTP---VPVFL---KSVSPANGKGKPKPKVPERKSSLISSVSISSSSTS 904
Q S TPTA+ + +FL +S P + +G P VP +SV +S+ +
Sbjct: 679 LGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEG-PHLSVP-------ASVIVSAPPPA 730
Query: 905 LSSSTST---EGSGTMKKLDPAVGSP-PAPPPPPV-----------PSPPFPCPADRSPF 949
+ +T +G+G + + SP PAP P PS P P SP
Sbjct: 731 QDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPH 790
Query: 950 LPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLP 1009
LP P P S+ P S PP P P C P P P + L
Sbjct: 791 LPSPHPTRPPSRPPSRPQSVSRPPSEP--------PLHPCPPPQAPPTLPGIFVIQNQLG 842
Query: 1010 LPPPL---LPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMP 1066
+PPP P++ PP PPL P+ P P SS S S+ E +SR P P
Sbjct: 843 VPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSS-AVASSSETSSRLPAP 901
Query: 1067 LITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEME 1126
+ LQ + G + T P AP P + T
Sbjct: 902 TPSDFQLQF------PPSQGPHKSPTPPPTLHLVPEPAAP----PPPPPRTFQMVTTPFP 951
Query: 1127 SESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPG---APSAGEAEARPSPSTTP- 1182
+ QP ++ + A S S G +P+A + +PS TP
Sbjct: 952 ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT 1011
Query: 1183 LPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVE-PAENVSEALRAVPSPTTG 1233
P +P+ P + P L +P K FA P NV++A + P +G
Sbjct: 1012 APSHAPAPAPMAATGLPPL---LPAENKAFASNLPTLNVAKAASSGPGKPSG 1060
Score = 48.1 bits (113), Expect = 7e-05
Identities = 118/529 (22%), Positives = 184/529 (34%), Gaps = 79/529 (14%)
Query: 848 PSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSS 907
P SGY + + P+ PV + VSP + + ++ ++ S+ + + S+
Sbjct: 258 PVSGYLASAAGPSE--PVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASA 315
Query: 908 STSTEGSGTMKKLDPAVGSPPAPPPPPV-----PSPPFPCPA----------DRSPFLPP 952
T T SG + P +GS P P P V P+P P PA PF P
Sbjct: 316 PTGTP-SGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPA 374
Query: 953 PPPVTDCSQGSPLPHSPV---------------------FPPPPPEALIPFCSPPDWCLS 991
+T + LP P FP P +A + F PP
Sbjct: 375 GATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANV-FKQPP----- 428
Query: 992 PPRPALSPILPDSPVSLPLPPPLL--PSSEPPPAPPLDP---KFMKDTRP----PFTNSG 1042
+P P +S P+ LL SS PA + P +F+ P P S
Sbjct: 429 ATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSA 488
Query: 1043 QPESSRGSLRPPSTKEETSR-PPMPLITTEALQ-MVQLRPV-RKNSGAEAAQLSERTAQE 1099
P + G + + + P++T + L + L PV +SGA +A + +
Sbjct: 489 LPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQ 548
Query: 1100 QRTPVAPQYHLKPSAFLKSRNS---------TNEMESESQPASVTSSLPTPAKSSSQGDH 1150
P Q + +A S T ++ + P S + L TP
Sbjct: 549 VGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATP 608
Query: 1151 GSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDS-SPSRKPPPISKKPKLFLVVPPPQ 1209
+A PV AP A A + P P P + P + P P + P P P
Sbjct: 609 AAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQ-ATTPQPS 667
Query: 1210 KDFAVEPAENV-SEALRAVPSPTTGEEG--SVHSREAKESSAAQAGSHATHPGTSVLEGG 1266
A P + V + A P+ ++ +E + + G H + P + ++
Sbjct: 668 PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAP 727
Query: 1267 AAGS----MSPSRVEANVPMVQPD--VSPAPKQEEPAENSADTGGDGES 1309
+P A + PD SPAP + PA +A G G S
Sbjct: 728 PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPA--AAPLKGPGPS 774
Score = 46.2 bits (108), Expect = 3e-04
Identities = 85/367 (23%), Positives = 128/367 (34%), Gaps = 41/367 (11%)
Query: 836 IMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISS 895
I + + HR+ P G S S + P P + +G P V ++S SS
Sbjct: 1212 IAASSEGHRL--PGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARAS--SS 1267
Query: 896 VSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPP 955
+S SSSS+S +SS + G M P+ PP+ + +
Sbjct: 1268 LSSSSSSSSAASSLDADEDGPM----------PSRNRPPIKTYEARSRIGLKLKIKQEAG 1317
Query: 956 VTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLL 1015
++ + L PV PPPP A + PP P P P ++ PPP
Sbjct: 1318 LSKVVHNTAL--DPVHQPPPPPATLKVAEPP-----PRPPPPPPPTGQMNGTVDHPPPAA 1370
Query: 1016 PSSEPPPAPPLDPK--FMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEA- 1072
P +P P P+ K R G PE + P S P+P EA
Sbjct: 1371 PERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGT-----PAGRARGGSPAPLPAKVDEAT 1425
Query: 1073 ------LQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNEME 1126
L V+ ++ + + AQ P L P+ KS + +
Sbjct: 1426 SGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQA 1485
Query: 1127 SESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDS 1186
S S + +L +S+ S R+P APS A + +P++ P P
Sbjct: 1486 SFSSDSPQDDTLTEHLQSAID----SILNLQQAPGRTP-APSYPHAASAGTPASPP-PLH 1539
Query: 1187 SPSRKPP 1193
P PP
Sbjct: 1540 RPEAYPP 1546
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 78.6 bits (192), Expect = 5e-14
Identities = 155/674 (22%), Positives = 231/674 (34%), Gaps = 114/674 (16%)
Query: 625 SSDGFGNPRHSVINVFVGRAQKNQGDRSNYQDKSLSRNISLKKAKKPPLPPSRTDSLRRI 684
S DG +P + I GR + S+ K+ + S KK K+ P +++ +R
Sbjct: 40 SPDGRTSPINEDIRSS-GRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQR- 97
Query: 685 PKKSSQCNGQVLNESLIATLQHSLQLSLP----GKSGSSPS-----QSPCSDLEE----- 730
K +S S Q + + P G+S S S S D+++
Sbjct: 98 EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRST 157
Query: 731 -PWLPR---SRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDY 786
P +P + S S SA M A P + + G TP+ S + P G
Sbjct: 158 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTP-GPTPSA 216
Query: 787 TGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVI 846
T + A PT P H+Q+ A PQ P P SP H +
Sbjct: 217 TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP-ALHPQRPPSPHPPPHPSP---HPPL 272
Query: 847 SPSSGYSSQSNTPTALTPV--------PVFLKSVSPANGKGKPKP-----KVPERKSSLI 893
P +G + Q + P+ P P L++ G P+P + + ++ L
Sbjct: 273 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 332
Query: 894 SSVSISSSSTSLS-----SSTSTEGSGTMKKLDPA-VGSPPAPPPPPVPSPPFPCP---- 943
+S + + TSL S+ ++ + L PA + P PPP P P P P
Sbjct: 333 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 392
Query: 944 -----ADRSPF-----LPPPPPVTDCS-------------------QGSPLPHSPVFPP- 973
+ SPF LPPPP + S Q PLP SP PP
Sbjct: 393 HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPG 452
Query: 974 -------PPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPL 1026
PPP A P PP A P +P P P+ PP PS+ PPA P
Sbjct: 453 LTQSQNLPPPPASHPPTGLHQVAPQPPF-AQHPFVPGGPP--PITPPTCPSTSTPPAGP- 508
Query: 1027 DPKFMKDTRPPFTNSGQPESS--RGSLRPPST----------KEETSRPPMPLITTEALQ 1074
+PP + + S GS P T EE PP P +
Sbjct: 509 ----GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP 564
Query: 1075 MVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNE-MESESQPAS 1133
V P + +++A+ + + + + P A K E +E + A
Sbjct: 565 TVVDTP---SHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAE 621
Query: 1134 VTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPP 1193
+ + + + ER R+ A S+ P + PS +PP
Sbjct: 622 QKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPP 681
Query: 1194 PISKKPKLFLVVPP 1207
P + VPP
Sbjct: 682 PTT-----IAAVPP 690
Score = 66.6 bits (161), Expect = 2e-10
Identities = 135/572 (23%), Positives = 205/572 (35%), Gaps = 89/572 (15%)
Query: 787 TGMQEDPGNPAGGCST------SSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPE 840
+G ++ P +P G S SSG + + + S+A + VK + SP
Sbjct: 32 SGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSND-SKAETVKKSAKKVKEEASSPL 90
Query: 841 KSHRVISP--SSGYSSQSNTPTALTPVPVFLKSVSPANGKGK--------------PKPK 884
KS++ +S T + T + SP+ G+G+ PK
Sbjct: 91 KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI 150
Query: 885 VPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPA 944
+ +S+ S SI S + S S S+ ++ PA+ +P P P +PP
Sbjct: 151 DQDNRST---SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP----- 202
Query: 945 DRSPFLPPPPPVTDCS----QGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPI 1000
+P LP P P + QGSP P P A +P PAL P
Sbjct: 203 -GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ------APALHPQ 255
Query: 1001 LPDSPVSLPLP---PPLLP---SSEPPPAPPLDPKFMKDTRPPFTNS---GQPESSRGSL 1051
P SP P P PPL P S+ P AP + PP +S G G
Sbjct: 256 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP 315
Query: 1052 RPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAP--QYH 1109
+P + S+ PL T+ A + +++A S++ +EQ P AP H
Sbjct: 316 QPFGLPPQASQGQAPLGTSPAAAYPHTS--LQLPASQSALQSQQPPREQPLPPAPLAMPH 373
Query: 1110 LKPSAFLK-------SRNSTNEMESESQPASVTSSLPTPAKS---SSQGDHGSAAERGGP 1159
+KP + S P S+ ++LP P SS H + P
Sbjct: 374 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 433
Query: 1160 VSRSPGAPSAGEAEARPSPSTTPLPD--SSPSRKPPPISKKPKLFLVVPPPQKDFAVE-- 1215
+ P +++P PS+ P + PPP + P L PQ FA
Sbjct: 434 LQLMP--------QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPF 485
Query: 1216 -PAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPS 1274
P PS +T G S + S AA +G + GG++ +
Sbjct: 486 VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGS--------IAGGSSCPLPTV 537
Query: 1275 RV--EANVPMVQPD-VSPAPKQEEPAENSADT 1303
++ EA +P+ P P+ P DT
Sbjct: 538 QIKEEALDDAEEPESPPPPPRSPSPEPTVVDT 569
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 78.6 bits (192), Expect = 5e-14
Identities = 155/674 (22%), Positives = 231/674 (34%), Gaps = 114/674 (16%)
Query: 625 SSDGFGNPRHSVINVFVGRAQKNQGDRSNYQDKSLSRNISLKKAKKPPLPPSRTDSLRRI 684
S DG +P + I GR + S+ K+ + S KK K+ P +++ +R
Sbjct: 594 SPDGRTSPINEDIRSS-GRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQR- 651
Query: 685 PKKSSQCNGQVLNESLIATLQHSLQLSLP----GKSGSSPS-----QSPCSDLEE----- 730
K +S S Q + + P G+S S S S D+++
Sbjct: 652 EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRST 711
Query: 731 -PWLPR---SRSQSTVSAGSSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDY 786
P +P + S S SA M A P + + G TP+ S + P G
Sbjct: 712 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTP-GPTPSA 770
Query: 787 TGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVI 846
T + A PT P H+Q+ A PQ P P SP H +
Sbjct: 771 TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP-ALHPQRPPSPHPPPHPSP---HPPL 826
Query: 847 SPSSGYSSQSNTPTALTPV--------PVFLKSVSPANGKGKPKP-----KVPERKSSLI 893
P +G + Q + P+ P P L++ G P+P + + ++ L
Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLG 886
Query: 894 SSVSISSSSTSLS-----SSTSTEGSGTMKKLDPA-VGSPPAPPPPPVPSPPFPCP---- 943
+S + + TSL S+ ++ + L PA + P PPP P P P P
Sbjct: 887 TSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHK 946
Query: 944 -----ADRSPF-----LPPPPPVTDCS-------------------QGSPLPHSPVFPP- 973
+ SPF LPPPP + S Q PLP SP PP
Sbjct: 947 HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPG 1006
Query: 974 -------PPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPL 1026
PPP A P PP A P +P P P+ PP PS+ PPA P
Sbjct: 1007 LTQSQNLPPPPASHPPTGLHQVAPQPPF-AQHPFVPGGPP--PITPPTCPSTSTPPAGP- 1062
Query: 1027 DPKFMKDTRPPFTNSGQPESS--RGSLRPPST----------KEETSRPPMPLITTEALQ 1074
+PP + + S GS P T EE PP P +
Sbjct: 1063 ----GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP 1118
Query: 1075 MVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPSAFLKSRNSTNE-MESESQPAS 1133
V P + +++A+ + + + + P A K E +E + A
Sbjct: 1119 TVVDTP---SHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAE 1175
Query: 1134 VTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPP 1193
+ + + + ER R+ A S+ P + PS +PP
Sbjct: 1176 QKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPP 1235
Query: 1194 PISKKPKLFLVVPP 1207
P + VPP
Sbjct: 1236 PTT-----IAAVPP 1244
Score = 66.6 bits (161), Expect = 2e-10
Identities = 135/572 (23%), Positives = 205/572 (35%), Gaps = 89/572 (15%)
Query: 787 TGMQEDPGNPAGGCST------SSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPE 840
+G ++ P +P G S SSG + + + S+A + VK + SP
Sbjct: 586 SGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSND-SKAETVKKSAKKVKEEASSPL 644
Query: 841 KSHRVISP--SSGYSSQSNTPTALTPVPVFLKSVSPANGKGK--------------PKPK 884
KS++ +S T + T + SP+ G+G+ PK
Sbjct: 645 KSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI 704
Query: 885 VPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPCPA 944
+ +S+ S SI S + S S S+ ++ PA+ +P P P +PP
Sbjct: 705 DQDNRST---SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP----- 756
Query: 945 DRSPFLPPPPPVTDCS----QGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPI 1000
+P LP P P + QGSP P P A +P PAL P
Sbjct: 757 -GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQ------APALHPQ 809
Query: 1001 LPDSPVSLPLP---PPLLP---SSEPPPAPPLDPKFMKDTRPPFTNS---GQPESSRGSL 1051
P SP P P PPL P S+ P AP + PP +S G G
Sbjct: 810 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP 869
Query: 1052 RPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAP--QYH 1109
+P + S+ PL T+ A + +++A S++ +EQ P AP H
Sbjct: 870 QPFGLPPQASQGQAPLGTSPAAAYPHTS--LQLPASQSALQSQQPPREQPLPPAPLAMPH 927
Query: 1110 LKPSAFLK-------SRNSTNEMESESQPASVTSSLPTPAKS---SSQGDHGSAAERGGP 1159
+KP + S P S+ ++LP P SS H + P
Sbjct: 928 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 987
Query: 1160 VSRSPGAPSAGEAEARPSPSTTPLPD--SSPSRKPPPISKKPKLFLVVPPPQKDFAVE-- 1215
+ P +++P PS+ P + PPP + P L PQ FA
Sbjct: 988 LQLMP--------QSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPF 1039
Query: 1216 -PAENVSEALRAVPSPTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPS 1274
P PS +T G S + S AA +G + GG++ +
Sbjct: 1040 VPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGS--------IAGGSSCPLPTV 1091
Query: 1275 RV--EANVPMVQPD-VSPAPKQEEPAENSADT 1303
++ EA +P+ P P+ P DT
Sbjct: 1092 QIKEEALDDAEEPESPPPPPRSPSPEPTVVDT 1123
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,082,694
Number of Sequences: 37866
Number of extensions: 5159740
Number of successful extensions: 70057
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 608
Number of HSP's successfully gapped in prelim test: 2121
Number of HSP's that attempted gapping in prelim test: 26114
Number of HSP's gapped (non-prelim): 20827
length of query: 1606
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1490
effective length of database: 13,855,062
effective search space: 20644042380
effective search space used: 20644042380
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.