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Search of human proteins with 114155140
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
(285 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 534 e-152
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 495 e-140
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 475 e-134
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 466 e-131
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 449 e-126
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 443 e-125
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 421 e-118
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 418 e-117
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 407 e-114
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 379 e-105
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 357 9e-99
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 352 2e-97
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 337 7e-93
gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens] 331 4e-91
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 330 9e-91
gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens] 327 7e-90
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 253 1e-67
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 88 7e-18
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 86 3e-17
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 86 3e-17
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 85 6e-17
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 84 1e-16
gi|221219020 NYD-SP11 protein [Homo sapiens] 83 3e-16
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 82 5e-16
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 79 6e-15
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 79 6e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 78 8e-15
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 78 8e-15
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 78 8e-15
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 78 8e-15
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 534 bits (1375), Expect = e-152
Identities = 285/285 (100%), Positives = 285/285 (100%)
Query: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK 60
MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK
Sbjct: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK 60
Query: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 120
YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA
Sbjct: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 120
Query: 121 ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERT 180
ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERT
Sbjct: 121 ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERT 180
Query: 181 EERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRA 240
EERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRA
Sbjct: 181 EERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRA 240
Query: 241 EFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
EFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI
Sbjct: 241 EFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 495 bits (1275), Expect = e-140
Identities = 259/284 (91%), Positives = 275/284 (96%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLEDEL ++QKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
SEALKDAQEKLELAEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
ERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
FAERSV KLEK+IDDLEDELYAQKLKYKAISEELDHALNDMTSI
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI 284
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 475 bits (1223), Expect = e-134
Identities = 245/284 (86%), Positives = 275/284 (96%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
M+AIKKKMQMLKLDKENA+DRAEQAEA++KQAE+R KQLE+E A+QKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
SE++K+AQEKLE AEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
DESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYEEVARKLVI+EG+LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
ERAE+AESKC +LEEELK VTNNLKSLEAQA+KYS KEDKYEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
FAERSVAKLEKTIDDLEDE+YAQK+KYKAISEELD+ALND+TS+
Sbjct: 241 FAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL 284
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 466 bits (1199), Expect = e-131
Identities = 244/284 (85%), Positives = 267/284 (94%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLEDEL ++QKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
SEALKDAQEKLELAEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
ERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
FAERSV KLEK+IDDLEDELYAQKLKYKAISEELDHALNDMTS+
Sbjct: 241 FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM 284
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 449 bits (1156), Expect = e-126
Identities = 236/284 (83%), Positives = 263/284 (92%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLEDEL ++QKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
SEALKDAQEKLELAEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
ERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
FAERSV KLEK+IDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 443 bits (1139), Expect = e-125
Identities = 229/284 (80%), Positives = 260/284 (91%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
MEAIKKKMQMLKLDKENA+DRAEQAEA++K AE++ KQ+E+EL +QKKLKGTEDELDKY
Sbjct: 1 MEAIKKKMQMLKLDKENAIDRAEQAEADKKAAEDKCKQVEEELTHLQKKLKGTEDELDKY 60
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
SE LKDAQEKLEL EKKA+DAE +VA+LNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
DESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADRKYEEVARKLVI+EG+LER E
Sbjct: 121 DESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
ERAE++E KC +LEEELKNVTNNLKSLEA +EKYS+KEDKYEEEIK+L+DKLKEAETRAE
Sbjct: 181 ERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAE 240
Query: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
FAER+VAKLEKTIDDLE++L K + + + LD LN++ I
Sbjct: 241 FAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI 284
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 421 bits (1083), Expect = e-118
Identities = 222/284 (78%), Positives = 255/284 (89%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLEDEL ++QKKLKGTEDELDKY
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY 60
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
SEALKDAQEKLELAEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
ERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
FAERSV KLEK+IDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 418 bits (1075), Expect = e-117
Identities = 219/284 (77%), Positives = 255/284 (89%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
M+AIKKKMQMLKLDKENA+DRAEQAEA++KQAE+R KQLE+E A+QKKLKGTEDE++KY
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
SE++K+AQEKLE AEKKA DAEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 SESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
DESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYEEVARKLVI+EG+LER+E
Sbjct: 121 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 180
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
ERAE+AES+ +LEEEL+ + LKSL A E+YS KEDKYEEEIK+L +KLKEAETRAE
Sbjct: 181 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 240
Query: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
FAERSVAKLEKTIDDLE+ L + K + I + LD L ++ ++
Sbjct: 241 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 284
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 407 bits (1047), Expect = e-114
Identities = 216/284 (76%), Positives = 251/284 (88%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLE+++AA +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
E L A++ L AE+ AA AEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
ERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 181 ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
FAERSV KLEK+IDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 379 bits (974), Expect = e-105
Identities = 202/284 (71%), Positives = 243/284 (85%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
M+AIKKKMQMLKLDKENALDRAEQAEA++K AE+RSKQLE+++AA +K L+ +EDE D+
Sbjct: 1 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV 60
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
E L A++ L AE+ AA AEA+VASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
Sbjct: 61 LEELHKAEDSLLAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 120
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
DESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKYEEVARKLVIIE DLER E
Sbjct: 121 DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE 180
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
ERAEL+E + +LEE+L+ + LK+L A +KYSQKED+YEEEIK+L+DKLKEAETRAE
Sbjct: 181 ERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAE 240
Query: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
FAERSV KLEK+IDDLE+++ K + ++ + LD L ++ ++
Sbjct: 241 FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM 284
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 357 bits (915), Expect = 9e-99
Identities = 191/239 (79%), Positives = 210/239 (87%)
Query: 44 LAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRA 103
+ A+++K++ + + D E + Q ++E + AEAEVASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 104 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 163
QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 164 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 223
EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 224 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 282
EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE+ LY+Q + + +S EL L+D+
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 352 bits (904), Expect = 2e-97
Identities = 190/242 (78%), Positives = 207/242 (85%)
Query: 44 LAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRA 103
+ A+++K++ + + D E + Q ++E + AEAEVASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 104 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 163
QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 164 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 223
EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 186
Query: 224 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMT 283
EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLED+L K ++ LD L D+
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLN 246
Query: 284 SI 285
+
Sbjct: 247 EM 248
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 337 bits (864), Expect = 7e-93
Identities = 178/238 (74%), Positives = 204/238 (85%)
Query: 44 LAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRA 103
L A+++K++ +++ D E Q +L+ K AEA+VASLNRRIQLVEEELDRA
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 104 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 163
QERLATALQKLEEAEKAADESERGMKVIE+RA KDEEKME+QEIQLKEAKHIAE+ADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 164 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 223
EEVARKLVIIE DLER EERAEL+E KC+ELEEELK VTNNLKSLEAQAEKYSQKED+YE
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 224 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALND 281
EEIK+L+DKLKEAETRAEFAERSV KLEK+IDDLED+LY Q + + ++ EL ALN+
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
Score = 70.9 bits (172), Expect = 1e-12
Identities = 54/237 (22%), Positives = 106/237 (44%), Gaps = 35/237 (14%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
+EA+++K++ L+ + A +RA + E + + E ++A++ ++++ E+ELD+
Sbjct: 7 LEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRA 66
Query: 62 SEALKDAQEKLELAEKKA-----------------------------------ADAEAEV 86
E L A +KLE AEK A DA+ +
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKY 126
Query: 87 ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQE 146
+ R++ ++E +L+RA+ER + K E E+ +K +E +A K +K + E
Sbjct: 127 EEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYE 186
Query: 147 IQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTN 203
++K +EA+ + E R + +E ++ E++ + L ELK N
Sbjct: 187 EEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALN 243
Score = 45.1 bits (105), Expect = 7e-05
Identities = 42/167 (25%), Positives = 76/167 (45%), Gaps = 37/167 (22%)
Query: 17 ENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGT----EDELDKYSEA-------- 64
E A A+++E K E R+++ E+++ + +LK ED KY E
Sbjct: 78 EEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIE 137
Query: 65 --LKDAQEKLELAEKKAADAEAEVASLNRRIQLVE--------------EELDRAQERLA 108
L+ A+E+ EL+E K A+ E E+ ++ ++ +E EE+ ++L
Sbjct: 138 SDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLK 197
Query: 109 TALQKLEEAEKAADESERGMKVIE---------NRALKDEEKMELQE 146
A + E AE++ + E+ + +E NR L +E K+ L E
Sbjct: 198 EAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNE 244
>gi|114155146 tropomyosin 3 isoform 3 [Homo sapiens]
Length = 247
Score = 331 bits (849), Expect = 4e-91
Identities = 176/239 (73%), Positives = 202/239 (84%)
Query: 44 LAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRA 103
+ A+++K++ + + D E + Q ++E + AEAEVASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 104 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 163
QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 164 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 223
EEVARKLVIIEGDLERTEERAELAES+C E++E+++ + NLK L A EKYSQKEDKYE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 224 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 282
EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE+ LY+Q + + +S EL L+D+
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLERNRLLSNELKLTLHDL 245
Score = 54.7 bits (130), Expect = 9e-08
Identities = 32/104 (30%), Positives = 56/104 (53%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
E + +K+ +++ D E +RAE AE+ ++ +E+ + ++ L + + + DKY
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQER 106
E +K +KL+ AE +A AE VA L + I +EE L ER
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEERLYSQLER 230
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 330 bits (846), Expect = 9e-91
Identities = 170/244 (69%), Positives = 207/244 (84%)
Query: 42 DELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELD 101
+ L A+++K++ + + D+ + + Q +L+ ++ AE +VA+LNRRIQLVEEELD
Sbjct: 5 NSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELD 64
Query: 102 RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 161
RAQERLATALQKLEEAEKAADESERGMKVIENRA+KDEEKME+QE+QLKEAKHIAEEADR
Sbjct: 65 RAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADR 124
Query: 162 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK 221
KYEEVARKLVI+EG+LER EERAE++E KC +LEEELKNVTNNLKSLEA +EKYS+KEDK
Sbjct: 125 KYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDK 184
Query: 222 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALND 281
YEEEIK+L+DKLKEAETRAEFAER+VAKLEKTIDDLE++L K + + + LD LN+
Sbjct: 185 YEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNE 244
Query: 282 MTSI 285
+ I
Sbjct: 245 LNCI 248
>gi|24119203 tropomyosin 3 isoform 2 [Homo sapiens]
Length = 248
Score = 327 bits (838), Expect = 7e-90
Identities = 175/242 (72%), Positives = 199/242 (82%)
Query: 44 LAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRA 103
+ A+++K++ + + D E + Q ++E + AEAEVASLNRRIQLVEEELDRA
Sbjct: 7 IEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRA 66
Query: 104 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 163
QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY
Sbjct: 67 QERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 126
Query: 164 EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE 223
EEVARKLVIIEGDLERTEERAELAES+C E++E+++ + NLK L A EKYSQKEDKYE
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 224 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMT 283
EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLED+L K ++ LD L D+
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQTLLDLN 246
Query: 284 SI 285
+
Sbjct: 247 EM 248
Score = 53.9 bits (128), Expect = 2e-07
Identities = 31/114 (27%), Positives = 61/114 (53%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
E + +K+ +++ D E +RAE AE+ ++ +E+ + ++ L + + + DKY
Sbjct: 127 EEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQKEDKYE 186
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEE 116
E +K +KL+ AE +A AE VA L + I +E++L +E + L++
Sbjct: 187 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ 240
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 253 bits (646), Expect = 1e-67
Identities = 148/284 (52%), Positives = 188/284 (66%), Gaps = 53/284 (18%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
M+AIKKKMQMLKLDK E+ +D+
Sbjct: 1 MDAIKKKMQMLKLDK--------------------------------------ENAIDRA 22
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
+A D ++ AE + E E +L ++++ E+E++ K E+EKAA
Sbjct: 23 EQAEADKKQ----AEDRCKQLEEEQQALQKKLKGTEDEVE-----------KYSESEKAA 67
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
DESERGMKVIENRA+KDEEKMELQE+QLKEAKHIAE++DRKYEEVARKLVI+EG+LER+E
Sbjct: 68 DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSE 127
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAE 241
ERAE+AES+ +LEEEL+ + LKSL A E+YS KEDKYEEEIK+L +KLKEAETRAE
Sbjct: 128 ERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAE 187
Query: 242 FAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
FAERSVAKLEKTIDDLE+ L + K + I + LD L ++ ++
Sbjct: 188 FAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL 231
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 88.2 bits (217), Expect = 7e-18
Identities = 68/282 (24%), Positives = 132/282 (46%), Gaps = 15/282 (5%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
M+ +++ + +E L +A++ E + K E QL++ELAA ++ + + E D+
Sbjct: 1647 MKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDEL 1706
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
++ + ++ K LA ++ EA +A L EEEL+ Q +L++A
Sbjct: 1707 ADEIANSSGKGALALEEKRRLEARIAQL-------EEELEEEQGNTELINDRLKKANLQI 1759
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD----RKYE----EVARKLVII 173
D+ + + + A K+E + E Q KE K +E + KY+ + K+ +
Sbjct: 1760 DQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL 1819
Query: 174 EGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKL 233
E L+ + + A + E++LK+V + AE+Y + DK +K L +L
Sbjct: 1820 EEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQL 1879
Query: 234 KEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
+EAE A+ A S KL++ ++D + A + ++ +L
Sbjct: 1880 EEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 73.6 bits (179), Expect = 2e-13
Identities = 63/271 (23%), Positives = 125/271 (46%), Gaps = 17/271 (6%)
Query: 7 KKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALK 66
KK++ L+ + E A + +AE++ + L +EL A++ +L+ T D E
Sbjct: 1104 KKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS 1163
Query: 67 DAQEKLELAEK----KAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 122
++++ + +K +A EA++ + ++ EEL E+ LE+A++
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL- 1222
Query: 123 ESERG-----MKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDL 177
E+ERG +KV+ E K + E QL+E + E +R E+A K+ ++ +L
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 178 ERTEERAELAESKCSE-------LEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILT 230
+ ++SK S+ LE +L++ L+ Q S K + E+E
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 231 DKLKEAETRAEFAERSVAKLEKTIDDLEDEL 261
++L+E E E+ +A L + D++ ++
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKKM 1373
Score = 71.6 bits (174), Expect = 7e-13
Identities = 67/278 (24%), Positives = 137/278 (49%), Gaps = 29/278 (10%)
Query: 8 KMQMLKLDKENALDRAE----QAEAEQKQAEERSKQLEDELAA----MQKKLKGTEDELD 59
K++ +L EN L E Q AE+ Q +E+ Q E EL A ++ +L + EL+
Sbjct: 856 KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQL-QAETELCAEAEELRARLTAKKQELE 914
Query: 60 KYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEK 119
E D + ++E E++ +AE + + IQ +EE+L+ + +A QKL + EK
Sbjct: 915 ---EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE----SARQKL-QLEK 966
Query: 120 AADES-----ERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVAR------ 168
E+ E ++E++ K ++ +L E ++ E E + K + +A+
Sbjct: 967 VTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHE 1026
Query: 169 -KLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIK 227
+ +E L R E++ + E +LE + ++++ + L+AQ + + K EEE++
Sbjct: 1027 AMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQ 1086
Query: 228 ILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
+++E + A + + +LE I +L+++L +++
Sbjct: 1087 AALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Score = 70.5 bits (171), Expect = 2e-12
Identities = 57/244 (23%), Positives = 120/244 (49%), Gaps = 10/244 (4%)
Query: 27 EAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEV 86
+ +Q+EE+ KQL ++ M+ +L EDE + S A+ A++KLE+ K D EA +
Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAEL---EDERKQRSMAVA-ARKKLEMDLK---DLEAHI 1626
Query: 87 ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQE 146
S N+ ++L + Q ++ +++L++ + +E K E + E +M +
Sbjct: 1627 DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 147 IQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLK 206
+L A+ +A ++ +E+A ++ G E E++ ++LEEEL+ N +
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1746
Query: 207 SLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKL 266
+ + +K + + D+ ++ + ++ E + ER +L+ + ++E + K
Sbjct: 1747 LINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTV---KS 1803
Query: 267 KYKA 270
KYKA
Sbjct: 1804 KYKA 1807
Score = 67.8 bits (164), Expect = 1e-11
Identities = 60/284 (21%), Positives = 140/284 (49%), Gaps = 23/284 (8%)
Query: 3 EAIKKKMQMLKLDK------ENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTED 56
EA+++K ++ +L+K E+ + + + E+ + LE ++ M+ +L+ ED
Sbjct: 1487 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELED 1546
Query: 57 ELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEE 116
EL +A +DA+ +LE+ + +A A R +Q +E+ + +++L ++++E
Sbjct: 1547 EL----QATEDAKLRLEV------NLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME- 1595
Query: 117 AEKAADESERGMKVIENRALKDEEKMELQEIQ--LKEAKHIAEEADRKYEEVARKLVIIE 174
AE + +R M V + L+ M+L++++ + A +EA ++ ++ ++
Sbjct: 1596 AELEDERKQRSMAVAARKKLE----MDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCM 1651
Query: 175 GDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLK 234
+L+ T E ++ E E++LK++ + L+ + + + + ++E L D++
Sbjct: 1652 RELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIA 1711
Query: 235 EAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHA 278
+ + A +LE I LE+EL ++ + I++ L A
Sbjct: 1712 NSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
Score = 67.0 bits (162), Expect = 2e-11
Identities = 62/283 (21%), Positives = 126/283 (44%), Gaps = 38/283 (13%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEA-----------EQKQAEERSKQLEDELAAMQKKL 51
E+ ++K+Q+ K+ E L + E+ + E+K E+R + L ++K
Sbjct: 956 ESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS 1015
Query: 52 KGTEDELDKYSEALKDAQEKLELAEKK--------------AADAEAEVASLNRRIQLVE 97
K +K+ + D +E+L EK+ + D ++A L +I ++
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELK 1075
Query: 98 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 157
+L + +E L AL ++EE + + + ++ +E++ + +E +E + +A+
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKR 1135
Query: 158 EADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQ 217
+ + E + +L E L+ T + EL + E+ K + K+ EAQ ++ Q
Sbjct: 1136 DLGEELEALKTEL---EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQ 1192
Query: 218 KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDE 260
K + EE L ++L++ +R A LEK LE+E
Sbjct: 1193 KHSQAVEE---LAEQLEQ-------TKRVKANLEKAKQTLENE 1225
Score = 65.5 bits (158), Expect = 5e-11
Identities = 67/273 (24%), Positives = 127/273 (46%), Gaps = 25/273 (9%)
Query: 16 KENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELA 75
K L + + E E EE ++ ++ A + +L E++ L EKL+L
Sbjct: 833 KVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRL----TEMETLQSQL--MAEKLQLQ 886
Query: 76 EKKAADAE--AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIEN 133
E+ A+ E AE L R+ ++EL+ L ++EE E+ + K ++
Sbjct: 887 EQLQAETELCAEAEELRARLTAKKQELEEICHDLEA---RVEEEEERCQHLQAEKKKMQQ 943
Query: 134 RALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSE 193
+ EE++E +E ++ + + K +++ + +I+E ++ +LA+ K
Sbjct: 944 NIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE------DQNCKLAKEK-KL 996
Query: 194 LEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKT 253
LE+ + T NL E +++ ++ ++K+E I L ++L+ E + + E++ KLE
Sbjct: 997 LEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGD 1056
Query: 254 IDDLED---ELYAQ----KLKYKAISEELDHAL 279
DL D EL AQ K++ EEL AL
Sbjct: 1057 STDLSDQIAELQAQIAELKMQLAKKEEELQAAL 1089
Score = 62.8 bits (151), Expect = 3e-10
Identities = 80/292 (27%), Positives = 138/292 (47%), Gaps = 44/292 (15%)
Query: 5 IKKKMQMLKLDKENALDRAEQAEAE-QKQAEERSKQLEDELAA---MQKKLKGTEDELDK 60
+KKKM+ D L+ AE+ + + QK E S++ E+++AA ++K + ELD
Sbjct: 1369 MKKKME----DSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDD 1424
Query: 61 YSEALKDAQEK---LELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEA 117
L ++ LE +KK AE +++ + EE DRA+ A A +K +A
Sbjct: 1425 LLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYA---EERDRAE---AEAREKETKA 1478
Query: 118 EKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDL 177
A E M E+K EL+ + K+ + E+ ++V + + +E
Sbjct: 1479 LSLARALEEAM----------EQKAELERLN-KQFRTEMEDLMSSKDDVGKSVHELEKSK 1527
Query: 178 ERTEERAELAESKCSELEEELKNVTN-------NLKSLEAQAEKYSQKEDKYEEEIK--- 227
E++ E +++ ELE+EL+ + NL++++AQ E+ Q D+ EE K
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQL 1587
Query: 228 ILTDKLKEAETRAEFAERSVA-----KLEKTIDDLEDEL-YAQKLKYKAISE 273
+ + EAE E +RS+A KLE + DLE + A K + +AI +
Sbjct: 1588 VRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ 1639
Score = 62.8 bits (151), Expect = 3e-10
Identities = 55/302 (18%), Positives = 142/302 (47%), Gaps = 19/302 (6%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
+E K ++Q D LD Q+ ++ +++ QL E + K D +
Sbjct: 1411 LEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAE 1470
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
+ + L A ++A + +AE+ LN++ + E+L +++ + ++ +LE++++A
Sbjct: 1471 AREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRAL 1530
Query: 122 DESERGMK-----------VIENRALKDEEKMELQEIQL-KEAKHIAEEADRKYEEVARK 169
++ MK E+ L+ E ++ + Q ++ + E+++ K +++ R+
Sbjct: 1531 EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQ 1590
Query: 170 LVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKIL 229
+ +E +LE ++ +A + +LE +LK++ ++ S ++ ++ K + ++K
Sbjct: 1591 VREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDC 1650
Query: 230 TDKL-------KEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDM 282
+L +E +A+ E+ + +E + L++EL A + + +E D +++
Sbjct: 1651 MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1710
Query: 283 TS 284
+
Sbjct: 1711 AN 1712
Score = 61.6 bits (148), Expect = 8e-10
Identities = 57/259 (22%), Positives = 113/259 (43%), Gaps = 14/259 (5%)
Query: 13 KLDKE-NALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEK 71
KL K+ +AL+ Q E Q E R K ++ KLK EDE + + E L++ +E
Sbjct: 1298 KLTKDFSALESQLQDTQELLQEENRQK------LSLSTKLKQVEDEKNSFREQLEEEEEA 1351
Query: 72 LELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 131
EK+ A A+VA + ++++ L+ A+E + LE + +E +
Sbjct: 1352 KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKL 1411
Query: 132 ENRALKDEEKMELQEIQLKEAKHIA---EEADRKYEEVARKLVIIEG----DLERTEERA 184
E + +++++ + L + A E+ +K++++ + I + +R E A
Sbjct: 1412 EKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEA 1471
Query: 185 ELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAE 244
E+K L L+ LE +++ + + + + E E E
Sbjct: 1472 REKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALE 1531
Query: 245 RSVAKLEKTIDDLEDELYA 263
+ V +++ +++LEDEL A
Sbjct: 1532 QQVEEMKTQLEELEDELQA 1550
Score = 59.3 bits (142), Expect = 4e-09
Identities = 69/281 (24%), Positives = 125/281 (44%), Gaps = 37/281 (13%)
Query: 17 ENALDRAEQAEAEQKQ----AEERSKQLEDELAAMQK---KLKGTEDELDKYSE---ALK 66
E +R + +AE+K+ +E +QLE+E +A QK + TE +L K E L+
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 67 DAQEKLELAEKKAADAEAEVASLNRRIQLVEEE--------LDRAQERLATAL-QKLEEA 117
D KL +K D AE + L EEE L E + T L ++L
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTT-----NLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE 1039
Query: 118 EKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDL 177
EK E E+ + +E + +++ + Q+ E K ++A+K ++ L
Sbjct: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELK----------MQLAKKEEELQAAL 1089
Query: 178 ERTEERA---ELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLK 234
R EE A +A K ELE ++ + +L+S A K +++ EE++ L +L+
Sbjct: 1090 ARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELE 1149
Query: 235 EAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
+ + +K E+ ++ L+ L + ++A +E+
Sbjct: 1150 DTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM 1190
Score = 58.9 bits (141), Expect = 5e-09
Identities = 48/257 (18%), Positives = 119/257 (46%), Gaps = 28/257 (10%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELA--------AMQKKLKGTEDE 57
+KK++ ++ + + AE ++QA++ +L DE+A A+++K + E
Sbjct: 1672 EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRR-LEAR 1730
Query: 58 LDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQL----------VEEELDRAQERL 107
+ + E L++ Q EL + A ++ +N + L ++L+R + L
Sbjct: 1731 IAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKEL 1790
Query: 108 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 167
LQ++E K+ + + + +E + + EE+++ + + + A ++K ++V
Sbjct: 1791 KVKLQEMEGTVKS--KYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVL 1848
Query: 168 RKLVIIEGDLERTEERAELAESKCSEL-------EEELKNVTNNLKSLEAQAEKYSQKED 220
++ + E+ +++A+ A ++ +L EEE + + + L+ + E ++ D
Sbjct: 1849 LQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETAD 1908
Query: 221 KYEEEIKILTDKLKEAE 237
E+ L +KL+ +
Sbjct: 1909 AMNREVSSLKNKLRRGD 1925
Score = 55.1 bits (131), Expect = 7e-08
Identities = 65/310 (20%), Positives = 131/310 (42%), Gaps = 36/310 (11%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
E K+ Q + + K+ + A+ EA+ ++ ++ Q +ELA ++ K + L+K
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELD---RAQERLATAL-QKLEEAE 118
+ L++ + +L K + + ++++ +EL ER+ T L K+ + +
Sbjct: 1220 QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQ 1279
Query: 119 KAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGD-- 176
D + ++++ K + E QL++ + + +E +R+ ++ KL +E +
Sbjct: 1280 VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339
Query: 177 -----LERTEE------------RAELAESK--------CSELEEELKNVTNNLKSLEAQ 211
LE EE A++A+ K C E EE+K K LE
Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQ--KDLEGL 1397
Query: 212 AEKYSQKE---DKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKY 268
++++ +K DK E+ L +L + + +S LEK + L +K
Sbjct: 1398 SQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTIS 1457
Query: 269 KAISEELDHA 278
+EE D A
Sbjct: 1458 AKYAEERDRA 1467
Score = 53.1 bits (126), Expect = 3e-07
Identities = 46/208 (22%), Positives = 98/208 (47%), Gaps = 21/208 (10%)
Query: 6 KKKMQMLKLDKENALDR--AEQAEAEQKQAEERSKQLEDEL---------------AAMQ 48
K +Q+ +++ + L+R A++ E ++Q E ++K+L+ +L A++
Sbjct: 1754 KANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALE 1813
Query: 49 KKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLA 108
K+ E++LD ++ + A +++ EKK D +V R + +++ D+A RL
Sbjct: 1814 AKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLK 1873
Query: 109 TALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY---EE 165
++LEEAE+ A + + ++ E + ++ K+ D +
Sbjct: 1874 QLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVPRR 1933
Query: 166 VARKLVIIEGDLERTEERAELAESKCSE 193
+ARK +G E + +A+ AE+K +E
Sbjct: 1934 MARK-GAGDGSDEEVDGKADGAEAKPAE 1960
Score = 43.5 bits (101), Expect = 2e-04
Identities = 44/187 (23%), Positives = 86/187 (45%), Gaps = 21/187 (11%)
Query: 97 EEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIA 156
EEE+ +E L K+ E + AA+ M+ ++++ + EK++LQE QL+ +
Sbjct: 844 EEEMMAKEEELV----KVREKQLAAENRLTEMETLQSQLMA--EKLQLQE-QLQAETELC 896
Query: 157 EEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYS 216
EA EE+ +L T ++ EL E C +LE ++ + L+A+ +K
Sbjct: 897 AEA----EELRARL---------TAKKQELEEI-CHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 217 QKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELD 276
Q + EE+++ ++ + E + KLE+ LED+ + K + + +
Sbjct: 943 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 277 HALNDMT 283
++T
Sbjct: 1003 EFTTNLT 1009
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 86.3 bits (212), Expect = 3e-17
Identities = 60/265 (22%), Positives = 134/265 (50%), Gaps = 4/265 (1%)
Query: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK 60
++E+ K ++Q+ D + L+RA Q Q+Q + + +L EL ++ KL+ +E +
Sbjct: 229 LVESEKSEIQLNVKDLKRKLERA-QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENEL 287
Query: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 120
++ + +EK+ E+K + E ++ +I+ EE++ R +E++ +K+ E E
Sbjct: 288 WNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 121 ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERT 180
E ++ E + + EEKM QE +++E E+ + EE+ R+ I E+
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKIREQEEKR 404
Query: 181 EERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRA 240
+E+ E K E +E+++ + E + + + EE+++ + +K++E E +
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 241 EFAERSVAKLEKTIDDLEDELYAQK 265
+ E + + E+ I + E++ + Q+
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQE 489
Score = 84.3 bits (207), Expect = 1e-16
Identities = 65/297 (21%), Positives = 148/297 (49%), Gaps = 29/297 (9%)
Query: 2 MEAIKKKMQMLKLDKE--NALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELD 59
++++ K+Q + E N L+ +Q E + + EE+ ++ E+++ + K++ E+++
Sbjct: 271 LQSVSAKLQAQVEENELWNLLN--QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
Query: 60 KYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEE--- 116
+ E + + +EK+ E K E ++ +I+ EE++ R +E++ +K++E
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
Query: 117 -----AEKAADE----------SERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 161
EK ++ E+ M+ + + + EE+M QE +++E + + ++ +
Sbjct: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
Query: 162 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK 221
K EV K+ E ++ EE+ + E K E EE+ T + L Q EK ++E+K
Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK----TWRQEKLLKQEEKIWEQEEK 504
Query: 222 ---YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
EE++ +K++E E + + E + + E + E+++ Q+++ + + E L
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 75.1 bits (183), Expect = 7e-14
Identities = 59/276 (21%), Positives = 132/276 (47%), Gaps = 23/276 (8%)
Query: 15 DKENALDRAEQAEAEQ----KQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDA-- 68
++E+ + R E+ EQ ++ EE+ + E+++ +K++ E+E+ + E +++
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 69 --QEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 126
QEK+ EKK + + ++ + EE++ +E + +KL E E+ E E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 127 GMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAEL 186
M+ E + + EEK++ QE + + + ++ ++ +E+ E + R EE+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ--------EEKMWRQEEKMWE 514
Query: 187 AESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEF---- 242
E K E EE+++ ++ E + + +K + E ++ L ++L + +AE
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGA 574
Query: 243 -AERSVAKLEKTIDDLEDELYAQKLKYKAISEELDH 277
E +L L+ EL +Q+ +++ ++ DH
Sbjct: 575 GRESGSQRLPTLTPILQVELKSQEA--QSLQQQQDH 608
Score = 70.9 bits (172), Expect = 1e-12
Identities = 54/236 (22%), Positives = 117/236 (49%), Gaps = 13/236 (5%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
E I+++ + + +E ++ E+ + + + E++ ++ ++++ ++++ E+++ +
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDR------AQERLATALQKLEE 116
E ++D +EKL E+K + E ++ +IQ EE++ QE+L +K+ E
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500
Query: 117 AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGD 176
E+ E M E + + EEKM+ QE +++E + + + K +E +L +E
Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560
Query: 177 LERTEERAEL-----AESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIK 227
L + ++AEL ES L + LKS EAQ+ Q++D Y ++
Sbjct: 561 LGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS--LQQQQDHYRGHLQ 614
Score = 56.6 bits (135), Expect = 2e-08
Identities = 60/279 (21%), Positives = 119/279 (42%), Gaps = 43/279 (15%)
Query: 8 KMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDEL-------DK 60
K L+L + A R E + E+ + + ++ + + K+ EL ++
Sbjct: 156 KKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEE 215
Query: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQ-----LVEEELDRAQERLATALQKLE 115
E + QEKL L E + ++ + V L R+++ L +++L +RL LQ +
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
Query: 116 EAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEG 175
+A E ++ + EEKM QE +++E + E + K E
Sbjct: 276 AKLQAQVEENELWNLLNQQ---QEEKMWRQEEKIQEQEEKMCEQELKIRE---------- 322
Query: 176 DLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKE 235
EE+ E K E EE+++ Q +K ++E+K E+ +K++E
Sbjct: 323 ----QEEKMWRQEEKMHEQEEKIRE----------QEDKMWRQEEKIREQ----EEKIRE 364
Query: 236 AETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEE 274
E + E + + ++ I + E+E++ Q+ K + E+
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
Score = 52.4 bits (124), Expect = 5e-07
Identities = 70/317 (22%), Positives = 140/317 (44%), Gaps = 42/317 (13%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEAL 65
+K+ + D+++ L+ +E ++ ++ + + L D+ A + + D+ +
Sbjct: 76 RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSF 135
Query: 66 KDAQEKLE---------LAEKKAADAEAEVASLNR-RIQLVEEEL--DRAQERLATALQK 113
K QEK+ + KK EV + R L+EE L D A R+ T ++K
Sbjct: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAV-RMGTYIEK 194
Query: 114 LEEAEKAADESERGMKVIENRALKD-----EEKMELQEIQLKEAKHIAEEADRKYEE--- 165
L + E+ A E I + LK+ +EK+ L E + E + ++ RK E
Sbjct: 195 LTK-ERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQL 253
Query: 166 -VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKS--LEAQAEKYSQKEDKY 222
+ ++ + +E D E ++ A+ + E EL N+ N + + Q EK ++E+K
Sbjct: 254 LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKM 313
Query: 223 -EEEIKILT----------------DKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
E+E+KI +K++E E + E + + E+ I + E++++ Q+
Sbjct: 314 CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQE 373
Query: 266 LKYKAISEELDHALNDM 282
K + E++ +M
Sbjct: 374 EKIREQDEKIQEQEEEM 390
Score = 42.7 bits (99), Expect = 4e-04
Identities = 37/174 (21%), Positives = 79/174 (45%), Gaps = 17/174 (9%)
Query: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLK-------- 52
MM+ ++K++ ++ + ++ ++ E + ++ EE+ ++ E++ +K LK
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 53 -----GTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERL 107
E+++ + E +++ +EK++ E+K + E + ++Q E L +ERL
Sbjct: 502 EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Query: 108 ATALQKLEEAEKAADESER----GMKVIENRALKDEEKMELQEIQLKEAKHIAE 157
QK E A ES + I LK +E LQ+ Q H+ +
Sbjct: 562 GKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQ 615
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 86.3 bits (212), Expect = 3e-17
Identities = 60/265 (22%), Positives = 134/265 (50%), Gaps = 4/265 (1%)
Query: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK 60
++E+ K ++Q+ D + L+RA Q Q+Q + + +L EL ++ KL+ +E +
Sbjct: 229 LVESEKSEIQLNVKDLKRKLERA-QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENEL 287
Query: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 120
++ + +EK+ E+K + E ++ +I+ EE++ R +E++ +K+ E E
Sbjct: 288 WNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347
Query: 121 ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERT 180
E ++ E + + EEKM QE +++E E+ + EE+ R+ I E+
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWRQEEKIREQEEKR 404
Query: 181 EERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRA 240
+E+ E K E +E+++ + E + + + EE+++ + +K++E E +
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464
Query: 241 EFAERSVAKLEKTIDDLEDELYAQK 265
+ E + + E+ I + E++ + Q+
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKTWRQE 489
Score = 84.3 bits (207), Expect = 1e-16
Identities = 65/297 (21%), Positives = 148/297 (49%), Gaps = 29/297 (9%)
Query: 2 MEAIKKKMQMLKLDKE--NALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELD 59
++++ K+Q + E N L+ +Q E + + EE+ ++ E+++ + K++ E+++
Sbjct: 271 LQSVSAKLQAQVEENELWNLLN--QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMW 328
Query: 60 KYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEE--- 116
+ E + + +EK+ E K E ++ +I+ EE++ R +E++ +K++E
Sbjct: 329 RQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
Query: 117 -----AEKAADE----------SERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR 161
EK ++ E+ M+ + + + EE+M QE +++E + + ++ +
Sbjct: 389 EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE 448
Query: 162 KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK 221
K EV K+ E ++ EE+ + E K E EE+ T + L Q EK ++E+K
Sbjct: 449 KLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK----TWRQEKLLKQEEKIWEQEEK 504
Query: 222 ---YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
EE++ +K++E E + + E + + E + E+++ Q+++ + + E L
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Score = 75.1 bits (183), Expect = 7e-14
Identities = 59/276 (21%), Positives = 132/276 (47%), Gaps = 23/276 (8%)
Query: 15 DKENALDRAEQAEAEQ----KQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDA-- 68
++E+ + R E+ EQ ++ EE+ + E+++ +K++ E+E+ + E +++
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 69 --QEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 126
QEK+ EKK + + ++ + EE++ +E + +KL E E+ E E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 127 GMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAEL 186
M+ E + + EEK++ QE + + + ++ ++ +E+ E + R EE+
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ--------EEKMWRQEEKMWE 514
Query: 187 AESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEF---- 242
E K E EE+++ ++ E + + +K + E ++ L ++L + +AE
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGA 574
Query: 243 -AERSVAKLEKTIDDLEDELYAQKLKYKAISEELDH 277
E +L L+ EL +Q+ +++ ++ DH
Sbjct: 575 GRESGSQRLPTLTPILQVELKSQEA--QSLQQQQDH 608
Score = 70.9 bits (172), Expect = 1e-12
Identities = 54/236 (22%), Positives = 117/236 (49%), Gaps = 13/236 (5%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
E I+++ + + +E ++ E+ + + + E++ ++ ++++ ++++ E+++ +
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDR------AQERLATALQKLEE 116
E ++D +EKL E+K + E ++ +IQ EE++ QE+L +K+ E
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500
Query: 117 AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGD 176
E+ E M E + + EEKM+ QE +++E + + + K +E +L +E
Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560
Query: 177 LERTEERAEL-----AESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIK 227
L + ++AEL ES L + LKS EAQ+ Q++D Y ++
Sbjct: 561 LGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQS--LQQQQDHYRGHLQ 614
Score = 56.6 bits (135), Expect = 2e-08
Identities = 60/279 (21%), Positives = 119/279 (42%), Gaps = 43/279 (15%)
Query: 8 KMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDEL-------DK 60
K L+L + A R E + E+ + + ++ + + K+ EL ++
Sbjct: 156 KKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEE 215
Query: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQ-----LVEEELDRAQERLATALQKLE 115
E + QEKL L E + ++ + V L R+++ L +++L +RL LQ +
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVS 275
Query: 116 EAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEG 175
+A E ++ + EEKM QE +++E + E + K E
Sbjct: 276 AKLQAQVEENELWNLLNQQ---QEEKMWRQEEKIQEQEEKMCEQELKIRE---------- 322
Query: 176 DLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKE 235
EE+ E K E EE+++ Q +K ++E+K E+ +K++E
Sbjct: 323 ----QEEKMWRQEEKMHEQEEKIRE----------QEDKMWRQEEKIREQ----EEKIRE 364
Query: 236 AETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEE 274
E + E + + ++ I + E+E++ Q+ K + E+
Sbjct: 365 QEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403
Score = 52.0 bits (123), Expect = 6e-07
Identities = 74/324 (22%), Positives = 142/324 (43%), Gaps = 56/324 (17%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEAL 65
+K+ + D+++ L+ +E ++ ++ + + L D+ A + + D+ +
Sbjct: 76 RKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSF 135
Query: 66 KDAQEKLE---------LAEKKAADAEAEVASLNR-RIQLVEEEL--DRAQERLATALQK 113
K QEK+ + KK EV + R L+EE L D A R+ T ++K
Sbjct: 136 KKRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAV-RMGTYIEK 194
Query: 114 LEEAEKA----------ADES--ERGMKVIENRALKDEEKMELQEIQLKEAKHIAE---- 157
L + A DE E+ ++ E L + EK E+Q + +K+ K E
Sbjct: 195 LTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ-LNVKDLKRKLERAQL 253
Query: 158 ---------EADR---KYEEVARKLV--IIEGDL-----ERTEERAELAESKCSELEEEL 198
EADR + + V+ KL + E +L ++ EE+ E K E EE++
Sbjct: 254 LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKM 313
Query: 199 KNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 258
LK E + + + Q+E +E+E +K++E E + E + + E+ I + E
Sbjct: 314 --CEQELKIREQEEKMWRQEEKMHEQE-----EKIREQEDKMWRQEEKIREQEEKIREQE 366
Query: 259 DELYAQKLKYKAISEELDHALNDM 282
++++ Q+ K + E++ +M
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEM 390
Score = 42.7 bits (99), Expect = 4e-04
Identities = 37/174 (21%), Positives = 79/174 (45%), Gaps = 17/174 (9%)
Query: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLK-------- 52
MM+ ++K++ ++ + ++ ++ E + ++ EE+ ++ E++ +K LK
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501
Query: 53 -----GTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERL 107
E+++ + E +++ +EK++ E+K + E + ++Q E L +ERL
Sbjct: 502 EEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Query: 108 ATALQKLEEAEKAADESER----GMKVIENRALKDEEKMELQEIQLKEAKHIAE 157
QK E A ES + I LK +E LQ+ Q H+ +
Sbjct: 562 GKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQQ 615
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 85.1 bits (209), Expect = 6e-17
Identities = 57/250 (22%), Positives = 125/250 (50%), Gaps = 19/250 (7%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTED------ 56
E I+++ + ++ +E + E+ ++K EE +Q ++E+ ++K++ E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 57 ELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEE 116
++ + E ++ +EK+ E+K D E ++ ++ EE++ +E++ +K+ E
Sbjct: 544 KIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603
Query: 117 AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGD 176
E+ E E M E + + EEKM+ QE +++ + E ++K E K+ E
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663
Query: 177 LERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK-YEEEIKI--LTDKL 233
++ EE+ E K E EE+ ++ Q EK ++E+K +E+E+++ +K+
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEK----------MQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Query: 234 KEAETRAEFA 243
+E + E A
Sbjct: 714 QEHQEHLEAA 723
Score = 82.4 bits (202), Expect = 4e-16
Identities = 63/282 (22%), Positives = 138/282 (48%), Gaps = 15/282 (5%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
E ++++ +M+ +E + E+ ++K E+ K+ E+E Q+K + E ++ +
Sbjct: 424 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 483
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA-- 120
E +++ +EK+ E+K E ++ + + ++ EEE + QE + +K+ E E+
Sbjct: 484 EKIREQEEKIREQEEKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 121 ----ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGD 176
E E ++ E + + EEKM QE +++E + + K E K+ E
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Query: 177 LERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK---YEEEIKILTDKL 233
+ EE + E K E EE++ + ++ Q EK ++E+K E++I+ +K+
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKM---CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657
Query: 234 KEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
+E E + E + + E+ + + E+++ Q+ K + E++
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Score = 74.7 bits (182), Expect = 9e-14
Identities = 67/289 (23%), Positives = 138/289 (47%), Gaps = 24/289 (8%)
Query: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQK---QAEERSKQLEDELAAMQKKLKGTEDE 57
++E+ K ++Q+ + + L+RA+ +Q+ +A+ K+L+ A +Q +++ E+E
Sbjct: 293 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE--ENE 350
Query: 58 L-----DKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQ 112
L + E + +EK++ E+K + E ++ +I+ EE++ R +E + +
Sbjct: 351 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 410
Query: 113 KLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE----VAR 168
K+ E+ E E M+ E + EEK+ E ++ E + I E+ +++ EE
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 470
Query: 169 KLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLE--AQAEKYSQKEDKYEEEI 226
K E + R EE+ E K E EE++ + E + EK ++E+ + +E
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530
Query: 227 KI--------LTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLK 267
KI +K+ E E + E + + E+ + D E+++ Q+ K
Sbjct: 531 KIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK 579
Score = 73.6 bits (179), Expect = 2e-13
Identities = 54/271 (19%), Positives = 127/271 (46%), Gaps = 7/271 (2%)
Query: 15 DKENALDRAEQAEAEQKQAEERSK--QLEDELAAMQKKLKGTEDELDKYSEALKDAQEKL 72
++E E+ ++K+ E+ +K + E+++ ++K++ E+++ + E + + QEK+
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE-QEKI 513
Query: 73 ELAEKKAADAEA----EVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 128
EK+ E E I +E++ +E++ +K+ E+ + E +
Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKI 573
Query: 129 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAE 188
+ E + + EEK+ QE +++E + E + +E K+ E + EE+ + E
Sbjct: 574 REQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 633
Query: 189 SKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVA 248
K EE+++ ++ E + + + + EE++ +K+ E E + + E +
Sbjct: 634 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 693
Query: 249 KLEKTIDDLEDELYAQKLKYKAISEELDHAL 279
+ E+ + + E L Q+ K + E L+ A+
Sbjct: 694 RQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 72.0 bits (175), Expect = 6e-13
Identities = 57/258 (22%), Positives = 120/258 (46%), Gaps = 16/258 (6%)
Query: 27 EAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEV 86
E E+K E+ K E +K E+++ + E + + +EK+ E+ + E ++
Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEK-----EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 440
Query: 87 ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADE------SERGMKVIENRALKDEE 140
L ++ E+E R QE +K+ E EK ++ E ++ E + + EE
Sbjct: 441 RELEEKMH--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 498
Query: 141 KMELQEIQLKEAKHIAEEADRKYEEV---ARKLVIIEGDLERTEERAELAESKCSELEEE 197
KM QE ++ E + I EE R+ +E + + + ++ R +E+ E K + EE+
Sbjct: 499 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEK 558
Query: 198 LKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDL 257
+ + E + + +K + EE+I+ +K++E E + E + E+ + +
Sbjct: 559 MWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQ 618
Query: 258 EDELYAQKLKYKAISEEL 275
E+++ Q+ K + E++
Sbjct: 619 EEKMCEQEEKMQEQEEKM 636
Score = 50.8 bits (120), Expect = 1e-06
Identities = 62/277 (22%), Positives = 123/277 (44%), Gaps = 42/277 (15%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEER-------SKQLEDELAAMQKKLKGTEDEL 58
K ++QM ++A+ +Q E E + R + +LE L+A+ + K +
Sbjct: 200 KTELQMALYYSQHAV---KQLEGEARDLISRLHDSWKFAGELEQALSAVATQKK----KA 252
Query: 59 DKYSEALKDAQE--KLELAEKKAADAEAEV--ASLNRRIQLVEEELDRAQERLATALQKL 114
D+Y E L ++ LEL D E + A L ++QLVE E Q + +KL
Sbjct: 253 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKL 312
Query: 115 EEA------EKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVAR 168
E A ++ E++ K +++ + K + ++E E+ + ++ + K
Sbjct: 313 ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW----NRLNQQQEEKMWRQEE 368
Query: 169 KLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKI 228
K+ E ++ EE+ E K E EE+++ Q E +KE+K + ++
Sbjct: 369 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRR----------QEEMMWEKEEKMRRQEEM 418
Query: 229 LTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
+ +K E + E + + E+ I +LE++++ Q+
Sbjct: 419 MWEK----EEKMRRQEEMMWEKEEKIRELEEKMHEQE 451
Score = 47.0 bits (110), Expect = 2e-05
Identities = 57/282 (20%), Positives = 117/282 (41%), Gaps = 36/282 (12%)
Query: 27 EAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAAD----- 81
E EQK + + + L EL A ++ + + AL +Q ++ E +A D
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 82 ------------AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMK 129
A + VA+ ++ EEL + ER A +L+ + E+ K
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTK--ERDALSLELYRNTITDEELKEKNAK 286
Query: 130 VIENRALKDEEKMELQEIQLKEAKHIAEEA---------DRKYEEVARKLVIIEGDLERT 180
+ E L + EK E+Q + +KE K E A + + + ++L + L+
Sbjct: 287 LQEKLQLVESEKSEIQ-LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 345
Query: 181 EERAEL-------AESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKL 233
E EL E K EE+++ ++ E + + +K + EE+++ + +
Sbjct: 346 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 405
Query: 234 KEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
E E + E + + E+ + E+ ++ ++ K + + E++
Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 447
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 84.3 bits (207), Expect = 1e-16
Identities = 60/275 (21%), Positives = 137/275 (49%), Gaps = 4/275 (1%)
Query: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK 60
++E+ K ++Q+ + + L+RA+ Q+Q + + L EL ++ KL+ +E +
Sbjct: 220 LVESEKSEIQLNVKELKRKLERAKLL-LPQQQLQAEADHLGKELQSVSAKLQAQVEENEL 278
Query: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 120
++ + +EK+ E+K + E ++ +I+ EE++ R +E + +K+ E+
Sbjct: 279 WNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 338
Query: 121 ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERT 180
E E ++ +E + + ++EK+ QE + +E + I E+ R+ +E K+ E +
Sbjct: 339 MWEKEEKIRELEEK-MHEQEKIREQEEKRQEEEKIREQEKRQEQEA--KMWRQEEKIREQ 395
Query: 181 EERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRA 240
EE+ E E EE++ + E + ++ +K + EE+I+ K++E E +
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455
Query: 241 EFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
E + + E+ + + E ++ Q+ K + E++
Sbjct: 456 REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM 490
Score = 80.5 bits (197), Expect = 2e-15
Identities = 58/252 (23%), Positives = 119/252 (47%), Gaps = 21/252 (8%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
E ++++ +M+ +E + E+ ++K E+ K+ E+E Q+K + E ++ +
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 122
E +++ +EK+ E+ + E ++ ++ EEE+ +E++ +K+ E EK
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 123 ESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEE 182
E E ++ E + EEKM QE ++ E + +E + K + R EE
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK--------------MRRQEE 495
Query: 183 RAELAESKCSELEEELKNVTNNLKSLE----AQAEKYSQKEDK---YEEEIKILTDKLKE 235
+ E K E EE+++ ++ E Q EK ++E+K EE+++ +K++E
Sbjct: 496 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 236 AETRAEFAERSV 247
E R E +
Sbjct: 556 QEVRLRQQEEKM 567
Score = 77.0 bits (188), Expect = 2e-14
Identities = 53/236 (22%), Positives = 118/236 (50%), Gaps = 4/236 (1%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
E + +K + ++ +E ++ + E E+K+ EE + +++ + K+ E+++ +
Sbjct: 337 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 396
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 122
E +++ +E ++ E+K + E ++ +Q EE++ R +E++ +K+ E E+
Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456
Query: 123 ESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEE 182
E E M+ E + + E KM QE +++E + + K E +K+ E + EE
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 183 RAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKY-EEEIKILTDKLKEAE 237
+ E K E EE++ + ++ Q EK ++E+K E+E+++ + K E
Sbjct: 517 MMQEQEEKMWEQEEKM---CEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 73.2 bits (178), Expect = 2e-13
Identities = 54/235 (22%), Positives = 116/235 (49%), Gaps = 14/235 (5%)
Query: 1 MMEAIKKKMQML--KLDKENALDRAEQAEAEQKQAEERSKQLEDE--LAAMQKKLKGTED 56
MM ++K++ L K+ ++ + E+ E+++ E+ K+ E E + ++K++ E+
Sbjct: 338 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 57 ELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEE 116
++ + E +++ +EK+ E+K + E E+ +++ EE++ ++++ +K+ E
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 117 AEKAADESERGM-----KVIENRAL--KDEEKMELQEIQLKEAKHIAEEADRKYEEVARK 169
E+ E E M K+ E A + EEKM QE +++E + E + K E
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517
Query: 170 LVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEE 224
+ E + EE+ E K E EE+++ ++ E + Q+E+K +E
Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV---RLRQQEEKMQE 569
Score = 72.4 bits (176), Expect = 4e-13
Identities = 56/281 (19%), Positives = 138/281 (49%), Gaps = 16/281 (5%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQK---QAEERSKQLEDELAAMQKKLKGTEDELD 59
E I+++ + ++ +E ++ E+ +++ + EE+ ++ E+ + ++K++ E+++
Sbjct: 295 EKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354
Query: 60 KYSEALKDAQEKLELAEK-----KAADAEAEVASLNRRIQLVEEELDRAQERLATALQKL 114
+ E +++ +EK + EK K + EA++ +I+ EE++ +E + +K+
Sbjct: 355 E-QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 115 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIE 174
E E+ E E M+ + EEKM QE +++E + E + K E + E
Sbjct: 414 GEQEEKMWEQEEEMQ-------EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 466
Query: 175 GDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLK 234
+ E + E+K E EE+++ ++ E + + +K + EE ++ +K+
Sbjct: 467 EKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 526
Query: 235 EAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
E E + E + + E+ + E+++ Q+++ + E++
Sbjct: 527 EQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKM 567
Score = 72.4 bits (176), Expect = 4e-13
Identities = 46/218 (21%), Positives = 109/218 (50%), Gaps = 3/218 (1%)
Query: 1 MMEAIKKKMQMLKLDKENAL---DRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDE 57
M E K + Q K +E + ++ ++ EA+ + EE+ ++ E+++ ++ ++ E++
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412
Query: 58 LDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEA 117
+ + E + + +E+++ E+K E ++ ++I+ EE++ +E + +K+ E
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
Query: 118 EKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDL 177
E E E M+ E + + EEK+ QE +++E + E + +E K+ E +
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 532
Query: 178 ERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKY 215
EE+ + E K EE+++ L+ E + +++
Sbjct: 533 CEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 70.5 bits (171), Expect = 2e-12
Identities = 66/264 (25%), Positives = 126/264 (47%), Gaps = 34/264 (12%)
Query: 38 KQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAE----KKAADAEA-----EVAS 88
++L+++ A +Q+KL+ E E + +K+ + KLE A+ ++ AEA E+ S
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 89 L--------------NRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENR 134
+ NR Q EE++ R +E++ +K++E E+ E E M+ E
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEM 324
Query: 135 ALKDEEKMELQE---------IQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAE 185
+ EEKM QE I+ E K +E R+ EE ++ I +R E+ A+
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Query: 186 L--AESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 243
+ E K E EE+++ ++ E + + +K + EEE++ +K++ E +
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444
Query: 244 ERSVAKLEKTIDDLEDELYAQKLK 267
E+ + + E+ I + E+ + Q+ K
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEK 468
Score = 31.6 bits (70), Expect = 0.83
Identities = 44/224 (19%), Positives = 95/224 (42%), Gaps = 32/224 (14%)
Query: 83 EAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRA------L 136
E E + ++ + + EL+ + + + E + A S+ +K +E A L
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 137 KDEEKM--ELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERT-------------- 180
D K EL++ L ++ADR EE+ ++ + +L R
Sbjct: 156 HDSWKFAGELEQA-LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 214
Query: 181 EERAELAESKCSELEEELKNVTNNLK--SLEAQAEKYSQKEDKYEEEIKILTDKLKEAET 238
+E+ +L ES+ SE++ +K + L+ L ++ + D +E++ ++ KL+
Sbjct: 215 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 274
Query: 239 RAEF-------AERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
E E + + E+ I + E+++ Q+ K + E++
Sbjct: 275 ENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKM 318
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 82.8 bits (203), Expect = 3e-16
Identities = 81/305 (26%), Positives = 151/305 (49%), Gaps = 28/305 (9%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQA----EERSKQLEDELAAMQKKL-----K 52
M + K K Q K ++E L+ E E+K+ E+R Q E + A + +K K
Sbjct: 1528 MLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKK 1587
Query: 53 GTEDELDKYSEALKDAQEKLELA--EKKAADAEAEVASLNRRIQLVEEELDRAQERLATA 110
++E E K AQE+ +LA E+K A A ++ +R + E + + +E LA
Sbjct: 1588 RAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQR 1647
Query: 111 LQKL-EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHI-----------AEE 158
+KL +EAEK A + ++ K E + ++EEK+ + +L E K+I +
Sbjct: 1648 GEKLSQEAEKLAQKRKKLAKKWE-KVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQN 1706
Query: 159 ADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK 218
D + +E+A++L +E D+E + E + +L EE K + ++L Q EK S++
Sbjct: 1707 LDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEE 1766
Query: 219 EDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHA 278
E K +E ++L ++E E A+ E+ + + E+ + ++L +K+K E ++
Sbjct: 1767 ETKLAQEEELL---IQEKEKLAQHKEK-MPEEEERLGRKREQLIEKKMKLAQKRERWINS 1822
Query: 279 LNDMT 283
+ ++T
Sbjct: 1823 MEELT 1827
Score = 67.4 bits (163), Expect = 1e-11
Identities = 61/275 (22%), Positives = 126/275 (45%), Gaps = 26/275 (9%)
Query: 19 ALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKK 78
AL + + E + Q E + +++ L +++L + +LD + + +L EKK
Sbjct: 2079 ALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKK 2138
Query: 79 AADAEAEVASLNRRIQLVEEELDRAQERLATALQK--LEEAEKAADESERGMKVIENR-- 134
A + ++A+ RR+ EE++ + +LA + L++ E+ E E + ++ R
Sbjct: 2139 LARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWR 2198
Query: 135 -------ALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELA 187
K +EK Q +++ +H +EE + +E+ ++ + + E EE E
Sbjct: 2199 KRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258
Query: 188 ESKCSELEEELK-------------NVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLK 234
E + E EEE K K E + E+ +KE+ +EE+ +I++++
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEET 2318
Query: 235 EAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYK 269
E+ + E E S + E+ D E E+ ++ ++K
Sbjct: 2319 ESLSDEEEEEESCSLEEEV--DREKEILKKEKQFK 2351
Score = 62.0 bits (149), Expect = 6e-10
Identities = 67/285 (23%), Positives = 135/285 (47%), Gaps = 10/285 (3%)
Query: 5 IKKKMQMLKLDKENALDRAEQAEAEQ-KQAEERSKQLEDE--LAAMQKKLKGTEDELDKY 61
+ ++++ L+ D E + E+ E+ K EE+ K E+E LA ++KL E +L +
Sbjct: 1714 LAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQE 1773
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQ--ERLATALQKLEEAEK 119
E L QEK +LA+ K E E +R QL+E+++ AQ ER ++++L + +
Sbjct: 1774 EELL--IQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKM 1831
Query: 120 AADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLER 179
+ + + +N A +++EK+ ++ L K + ++ +V KL + L +
Sbjct: 1832 ILYQKKNLAQEKKNLA-QEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQ 1890
Query: 180 TEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETR 239
EE+ L + K + ++++ K K ++ + ++E +E++K+ +K +
Sbjct: 1891 VEEK--LTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKK 1948
Query: 240 AEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTS 284
E +AK EK ++ L +K++ E L TS
Sbjct: 1949 RLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETS 1993
Score = 58.9 bits (141), Expect = 5e-09
Identities = 64/295 (21%), Positives = 133/295 (45%), Gaps = 28/295 (9%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
+ I+KKM++ + +E ++ E+ + K + K L E +K L +++L +
Sbjct: 1804 QLIEKKMKLAQ-KRERWINSMEEL-TKNKMILYQKKNLAQE----KKNLAQEKEKLAQRK 1857
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 122
E L +E+L ++K+ + ++ N+ + VEE+L + +E + +KL E EK
Sbjct: 1858 ENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLV 1917
Query: 123 ESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLER-TE 181
+ E + + + +++ K+ L++ ++ K + E D EE A L +++R E
Sbjct: 1918 QVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNL-----EMKRLAE 1972
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKL------KE 235
E+ L E K + + E + K + + E + +K EE+I + D++ +
Sbjct: 1973 EKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKL-SLEEKILLHEDRILAMEESEI 2031
Query: 236 AETRAEF---------AERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALND 281
A+ + EF +R +AK + + + L + K I + L D
Sbjct: 2032 AKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRD 2086
Score = 52.8 bits (125), Expect = 3e-07
Identities = 65/292 (22%), Positives = 130/292 (44%), Gaps = 38/292 (13%)
Query: 21 DRAEQAEAEQK--QAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKL-----E 73
D E A+AE K Q EE Q ++L+ +KL +L K E + +EKL +
Sbjct: 1626 DDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGK 1685
Query: 74 LAEKK--AADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 131
LAE K A E+ + + E+EL + E L +++L E+ ++ E G V
Sbjct: 1686 LAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQ-EEGKLVE 1744
Query: 132 ENRALKDEEK----------------MELQEIQLKEAKHIAEEADRKYEEVARKLVIIEG 175
E + L +EE+ + +E+ ++E + +A+ ++ EE R E
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQ 1804
Query: 176 DLERTEERAELAESKCSELEE---------ELKNVTNNLKSLEAQAEKYSQKEDKY---E 223
+E+ + A+ E + +EE + KN+ K+L + EK +Q+++ +
Sbjct: 1805 LIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNK 1864
Query: 224 EEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
E + +L + + + + +A++E+ + ++ + +K K ++L
Sbjct: 1865 ERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKL 1916
Score = 49.7 bits (117), Expect = 3e-06
Identities = 65/273 (23%), Positives = 130/273 (47%), Gaps = 25/273 (9%)
Query: 14 LDKENALDRAEQAEAEQKQ--AEERSK---------QLEDELAAMQKKLKGTEDELDKYS 62
++++ L E+A A Q++ +EE +K Q +++LA ++K+ E+ L +
Sbjct: 1743 VEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKR 1802
Query: 63 EALKDAQEKLELAEKKAADAEAEVAS----LNRRIQLVEEELDRAQ--ERLATALQKLEE 116
E L + + KL ++ ++ E+ L ++ L +E+ + AQ E+LA + L
Sbjct: 1803 EQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLY 1862
Query: 117 AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGD 176
++ S++ + ++N+ + + E +L + K + K E +KLV +E
Sbjct: 1863 NKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDS 1922
Query: 177 LERTEERAELAESKCS-ELEEELKNVTNNLK-SLE-AQAEKYSQKEDKYEEEIKILTDKL 233
L + +E+ LA+ K LE+ + L+ L+ A+ EK E K E K+ +
Sbjct: 1923 LAKKQEK--LAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEG 1980
Query: 234 KEAETRAEFAERSVAKLEKTIDDLEDELYAQKL 266
KE ++ E E S ++ + +E EL+ +KL
Sbjct: 1981 KETLSKGETPETS---RQRKMTQVEQELFERKL 2010
Score = 49.7 bits (117), Expect = 3e-06
Identities = 74/328 (22%), Positives = 144/328 (43%), Gaps = 58/328 (17%)
Query: 3 EAIKKKMQMLKLDKENALDRAE---QAEAEQKQAEERSKQLEDEL----AAMQKKLKGTE 55
+A+ +M+ L +K ++ E + E + + + Q+E EL ++++K+ E
Sbjct: 1961 KALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHE 2020
Query: 56 DELDKYSEALKDAQEKLELA--EKKAADAEAEVASLNRRIQLVEEELDRAQERL---ATA 110
D + E+ + A+ KLE ++ + ++A +R++ E L + +L A
Sbjct: 2021 DRILAMEES-EIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKA 2079
Query: 111 LQKLEEAEKAADESE-------RGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY 163
LQKL E+ + E R + V E R ++ K++++E E + + ++K
Sbjct: 2080 LQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKL 2139
Query: 164 EEVARKLV-----IIEGDLERTEERAELAESKCSE----------LEEE-----LKNVTN 203
RKL +I + + TEE ++LA K SE +EEE LK
Sbjct: 2140 ARKQRKLANKMRRMINKEEKMTEEESKLAR-KHSEVILDDEEEGGIEEEEVIPFLKRRWR 2198
Query: 204 NLKSL---EAQAEKYS------QKEDKYEEEIKILTDKL--------KEAETRAEFAERS 246
K + EK+S + E+ + EE++ L D+L +E E R E ER
Sbjct: 2199 KRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258
Query: 247 VAKLEKTIDDLEDELYAQKLKYKAISEE 274
++ + ++ ++E ++ + + EE
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKEEEE 2286
Score = 49.3 bits (116), Expect = 4e-06
Identities = 70/334 (20%), Positives = 134/334 (40%), Gaps = 73/334 (21%)
Query: 5 IKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEA 64
+KK +++ L+ N E ++ E+K+ ++S + + ++K+ + E+ K
Sbjct: 1367 LKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERD 1426
Query: 65 LKDAQEKLELAEKKAADAEAEVASLNR--------------------------------- 91
+ + E++ E+K E ++ + R
Sbjct: 1427 MSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWE 1486
Query: 92 -RIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIEN--------RALKDEEKM 142
R+ EE+L +A E+L+ + L+E +K + E +V EN + KDEE++
Sbjct: 1487 KRLLQEEEKLHQAGEKLSPEEEMLQEDKKL--KWEEWKQVWENMLSSKSKEQQYKDEEEV 1544
Query: 143 ELQEIQLKEA-----------KHIAEE-----ADRKYEEVARKLVIIEGDLERTEERAEL 186
L+E +E +HI EE RK +K E L + EE+
Sbjct: 1545 TLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQ 1604
Query: 187 AESKCSELEEELK----NVTNNLKSLEAQAEKYSQKE-------DKYEEEIKILTDKLKE 235
E + ++ E +L +T + + + K++QKE +K +E + L K K+
Sbjct: 1605 EERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKK 1664
Query: 236 AETRAEFAERSVAKLEKTIDDLED--ELYAQKLK 267
+ E R KL K L + + AQK++
Sbjct: 1665 LAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVE 1698
Score = 42.4 bits (98), Expect = 5e-04
Identities = 34/120 (28%), Positives = 61/120 (50%), Gaps = 7/120 (5%)
Query: 7 KKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALK 66
+K + L ++E + E+ E E+ + EE ++ E+E Q + + E + K + +
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKE 2297
Query: 67 DAQEKLEL-AEKKAADAEAEVASLNRRIQ-----LVEEELDRAQERLATALQ-KLEEAEK 119
+ QEK E+ EK+ +E E SL+ + +EEE+DR +E L Q KL+E +
Sbjct: 2298 EVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRR 2357
Score = 41.2 bits (95), Expect = 0.001
Identities = 67/292 (22%), Positives = 121/292 (41%), Gaps = 50/292 (17%)
Query: 3 EAIKKKMQML--KLDKENAL--DRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDEL 58
E ++M+ L +L+K+ +L + E+ E E+++ EE ++ E+E +++ +G E ++
Sbjct: 2224 EHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEE---RKEEEEGEEKQV 2280
Query: 59 DKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAE 118
+K E ++K + EKK +Q EE + +E + EE E
Sbjct: 2281 EKEEE-----EKKKKKKEKK-----------KEEVQEKEEVFEEKEE-----IMSEEETE 2319
Query: 119 KAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLE 178
+DE E E +EE +EI KE + +E RK +++ I +
Sbjct: 2320 SLSDEEEE-----EESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVP 2374
Query: 179 RTEERAELAESKCSELEEELKNVTNNLKSLEAQA-----EKYSQKEDKYEEEIKI----- 228
+ RA + L+ LK + + ++ + EK EDK ++I
Sbjct: 2375 HGKGRA----IRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWEDKKATVVEIPRKFL 2430
Query: 229 -LTDKLKEAETRAEFAERSV--AKLEKTIDDLEDELYAQKLKYKAISEELDH 277
DK +E + E V LE DL+ + L+ +EEL H
Sbjct: 2431 GTMDKEREVMGKYEPIPPHVLGTVLESQAQDLKTPFMSHILRRTVEAEELQH 2482
Score = 37.4 bits (85), Expect = 0.015
Identities = 43/191 (22%), Positives = 87/191 (45%), Gaps = 26/191 (13%)
Query: 14 LDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK---YSEALKDAQE 70
+++E + ++ ++K+A+ K E K DE++ +SE ++ +
Sbjct: 2184 IEEEEVIPFLKRRWRKRKEAKRGDKPKE--------KFSSQVDEVESEEHFSEEMESLLD 2235
Query: 71 KLELAEKKAADAEAEVASLNRRIQ--LVEEELDRAQERLATALQKLEEAEKAADESERGM 128
+LE E +++ E E R + + EEE +R +E EE E+ E E
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEE---------EEGEEKQVEKEEEE 2286
Query: 129 KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKY--EEVARKLVIIEGDLERTEERAEL 186
K + + K EE E +E+ ++ + ++EE EE + +E +++R E+ L
Sbjct: 2287 KKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDR--EKEIL 2344
Query: 187 AESKCSELEEE 197
+ K +L+E+
Sbjct: 2345 KKEKQFKLQEQ 2355
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 82.0 bits (201), Expect = 5e-16
Identities = 70/272 (25%), Positives = 129/272 (47%), Gaps = 23/272 (8%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
++A + QML L +R + E ++ EER ++ E+ L +++L+ E+ L +
Sbjct: 180 LQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQ 239
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA 121
E L + +E+L E++ + E + R++ EE L +ERL ++L E E+
Sbjct: 240 EERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERL 299
Query: 122 DESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTE 181
E E ++ E R + EE++ QE +L E + + + +R EEV + ++E + + E
Sbjct: 300 CEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQ-ERLLEEVEK---LLEQERRQEE 355
Query: 182 ERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYE-EEIKILTDKL------- 233
+ L + E EEL + L Q E+ Q+E E E ++ L L
Sbjct: 356 QERLLERERLLEEVEELL----EQERLRQQDERLWQQETLQELERLRELERMLELGWEAL 411
Query: 234 --KEAETRAEFAE-----RSVAKLEKTIDDLE 258
+ AE R+ F E +S +LE+ + +L+
Sbjct: 412 YEQRAEPRSGFEELNNENKSTLQLEQQVKELK 443
Score = 76.6 bits (187), Expect = 2e-14
Identities = 72/284 (25%), Positives = 135/284 (47%), Gaps = 23/284 (8%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQA--------EERSKQLEDELAAMQKKLKG 53
+E ++ + L+ + E+ + R QAE E Q EER ++ E+ L +++L+
Sbjct: 159 VEQLQDETNHLRKELES-VGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLRE 217
Query: 54 TEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQK 113
E+ L + E L++ +E+L E++ + E + R+ EE L +ERL ++
Sbjct: 218 QEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEER 277
Query: 114 LEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVII 173
L E E+ E E ++ E R + EE++ QE +L E EE R+ EE + +
Sbjct: 278 LHEQEERLCEQEERLREQEERLCEQEERLREQEERLCE----QEERLREQEERLCEQEKL 333
Query: 174 EGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKL 233
G EE +L E + +EE + + + LE E Q+ + ++E +L
Sbjct: 334 PGQERLLEEVEKLLEQE--RRQEEQERLLERERLLEEVEELLEQERLRQQDE------RL 385
Query: 234 KEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDH 277
+ ET E + +LE+ ++ + LY Q+ + ++ EEL++
Sbjct: 386 WQQETLQEL--ERLRELERMLELGWEALYEQRAEPRSGFEELNN 427
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 78.6 bits (192), Expect = 6e-15
Identities = 70/325 (21%), Positives = 150/325 (46%), Gaps = 47/325 (14%)
Query: 2 MEAIKKKMQMLKLDKEN---ALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDEL 58
M ++K++++ L+ D N AL E+A AE+++ ER K+ D + + ++E+
Sbjct: 594 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEI 647
Query: 59 DKYSEALKDAQEKLELAEKKAADAEAEVASL--------------NRRIQLVEEELDRAQ 104
D Y + LKD +EK+ L + ++ EA + L + R++ +E L++ +
Sbjct: 648 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 707
Query: 105 ERLATALQKLEEAEKAADESERGMKVI--------ENRALKDEEKMELQEIQ-----LKE 151
E +L++A +AA E+ ++ E KDE E+ LKE
Sbjct: 708 EECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKE 767
Query: 152 AKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLK----- 206
++ + D+K E+ R++ + + + ++ + K +++ EE + +NL
Sbjct: 768 VENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQ 827
Query: 207 ---SLEAQAEKYSQKEDKYEEEIKILTDK---LKEAETRAEFAERSVAKLEKTIDDLEDE 260
SL + ++ + E+ E ++I ++ L + E+ AE+ V +L ++ ++ E
Sbjct: 828 LQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQE 887
Query: 261 LYAQKLKYKAISEELDHALNDMTSI 285
L + K K + + L +T++
Sbjct: 888 LESMKAKLSSTQQSLAEKETHLTNL 912
Score = 73.9 bits (180), Expect = 1e-13
Identities = 70/292 (23%), Positives = 142/292 (48%), Gaps = 25/292 (8%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERS---KQLEDELAAMQKKLKGTEDELDKYS 62
+KK + LK+ E+ L +A +A E + + E S + LE E+ + + + E+D+
Sbjct: 705 QKKEECLKM--ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 762
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 122
E LK+ + + +KK A+ E +V N+++ ++ + +++ A Q LEEA + D
Sbjct: 763 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRRED 819
Query: 123 ESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR--KYEEVAR-----KLVIIEG 175
+ +++ K ++++E E L+E+ I E + EE AR ++ +
Sbjct: 820 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 879
Query: 176 DLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK--EDKYEEEIKILTDK- 232
+E+ ++ E ++K S ++ L +L +L A+ K+ ++ E K E + +++K
Sbjct: 880 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD 939
Query: 233 ----LKEAETRAEFAERSVAKLEKTIDDLEDELYAQ---KLKYKAISEELDH 277
L E + + + VA L++ D L +L Q ++K A + E DH
Sbjct: 940 ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDH 991
Score = 71.2 bits (173), Expect = 9e-13
Identities = 54/281 (19%), Positives = 132/281 (46%), Gaps = 24/281 (8%)
Query: 5 IKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEA 64
+++++QMLK N E+ E E KQ E + K ++++++ E
Sbjct: 401 LEEEIQMLK---SNGALSTEEREEEMKQME-----------VYRSHSKFMKNKVEQLKEE 446
Query: 65 LKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 124
L + + E +KKAA +AE+ + + + + EL Q +L T + ++++ +
Sbjct: 447 LSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVL 506
Query: 125 ERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERA 184
+ + E RA + +++ ++L+E + + + ++ +++A + G++ ++
Sbjct: 507 KESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML 566
Query: 185 ELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAE 244
++ E K + L+++++N+ L+ E Q +E +K L +T E
Sbjct: 567 DVKERKVNVLQKKIENLQEQLRDKEKQM-------SSLKERVKSLQADTTNTDTALTTLE 619
Query: 245 RSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
++A+ E+TI+ L+++ + + EE+D+ D+ +
Sbjct: 620 EALAEKERTIERLKEQ---RDRDEREKQEEIDNYKKDLKDL 657
Score = 63.2 bits (152), Expect = 3e-10
Identities = 74/337 (21%), Positives = 147/337 (43%), Gaps = 59/337 (17%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKY 61
+E +K+++ + E +A +AE Q ++ + + EL A+Q KL+ ++
Sbjct: 440 VEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDS 499
Query: 62 SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEEL--------DRAQERLATALQK 113
+ ++ +E L E++AA + EV +L R++ E L D A+E+ T +
Sbjct: 500 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEK-GTQAGE 558
Query: 114 LEEAEKAADESERGMKVIENR------ALKDEEKM------ELQEIQ------------L 149
+ + + D ER + V++ + L+D+EK ++ +Q L
Sbjct: 559 IHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL 618
Query: 150 KEA--------KHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNV 201
+EA + + E+ DR E ++ + DL+ +E+ L + SE E L ++
Sbjct: 619 EEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDL 678
Query: 202 --------------TNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSV 247
+ LK+LE E+ ++ K E ++K + EA E ++R +
Sbjct: 679 KEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDR-I 737
Query: 248 AKLEKTIDDLEDE---LYAQKLKYKAISEELDHALND 281
LE+ I +DE A+ + I +E+++ ND
Sbjct: 738 QHLEREITRYKDESSKAQAEVDRLLEILKEVENEKND 774
Score = 55.1 bits (131), Expect = 7e-08
Identities = 56/319 (17%), Positives = 138/319 (43%), Gaps = 43/319 (13%)
Query: 3 EAIKKKMQML-------KLDKENALDRAEQAEAEQ---------KQAEERSKQLEDEL-- 44
E+IKK ++ML K +E+ AEAE +Q E+ + L +E+
Sbjct: 307 ESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHR 366
Query: 45 -----------AAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRI 93
A+Q ++ + ++ L+D +E++++ + A +++ R
Sbjct: 367 RFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGA-----LSTEEREE 421
Query: 94 QLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRA--LKDEEKMELQEIQLKE 151
++ + E+ R+ + K+E+ ++ E + ++ +A L+ E QE+ K+
Sbjct: 422 EMKQMEVYRSHSKFMK--NKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKD 479
Query: 152 AKHIA-----EEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLK 206
+ +A E ++ + + + +++ L E+RA + +++ L L+ L
Sbjct: 480 TELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLN 539
Query: 207 SLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKL 266
Q + ++++ EI L D L E + ++ + L++ + D E ++ + K
Sbjct: 540 KKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKE 599
Query: 267 KYKAISEELDHALNDMTSI 285
+ K++ + + +T++
Sbjct: 600 RVKSLQADTTNTDTALTTL 618
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 78.6 bits (192), Expect = 6e-15
Identities = 70/325 (21%), Positives = 150/325 (46%), Gaps = 47/325 (14%)
Query: 2 MEAIKKKMQMLKLDKEN---ALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDEL 58
M ++K++++ L+ D N AL E+A AE+++ ER K+ D + + ++E+
Sbjct: 566 MSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRD------RDEREKQEEI 619
Query: 59 DKYSEALKDAQEKLELAEKKAADAEAEVASL--------------NRRIQLVEEELDRAQ 104
D Y + LKD +EK+ L + ++ EA + L + R++ +E L++ +
Sbjct: 620 DNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKK 679
Query: 105 ERLATALQKLEEAEKAADESERGMKVI--------ENRALKDEEKMELQEIQ-----LKE 151
E +L++A +AA E+ ++ E KDE E+ LKE
Sbjct: 680 EECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKE 739
Query: 152 AKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLK----- 206
++ + D+K E+ R++ + + + ++ + K +++ EE + +NL
Sbjct: 740 VENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQ 799
Query: 207 ---SLEAQAEKYSQKEDKYEEEIKILTDK---LKEAETRAEFAERSVAKLEKTIDDLEDE 260
SL + ++ + E+ E ++I ++ L + E+ AE+ V +L ++ ++ E
Sbjct: 800 LQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQE 859
Query: 261 LYAQKLKYKAISEELDHALNDMTSI 285
L + K K + + L +T++
Sbjct: 860 LESMKAKLSSTQQSLAEKETHLTNL 884
Score = 73.9 bits (180), Expect = 1e-13
Identities = 70/292 (23%), Positives = 142/292 (48%), Gaps = 25/292 (8%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERS---KQLEDELAAMQKKLKGTEDELDKYS 62
+KK + LK+ E+ L +A +A E + + E S + LE E+ + + + E+D+
Sbjct: 677 QKKEECLKM--ESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 734
Query: 63 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAAD 122
E LK+ + + +KK A+ E +V N+++ ++ + +++ A Q LEEA + D
Sbjct: 735 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA---QMLEEARRRED 791
Query: 123 ESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADR--KYEEVAR-----KLVIIEG 175
+ +++ K ++++E E L+E+ I E + EE AR ++ +
Sbjct: 792 NLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLM 851
Query: 176 DLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQK--EDKYEEEIKILTDK- 232
+E+ ++ E ++K S ++ L +L +L A+ K+ ++ E K E + +++K
Sbjct: 852 AMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKD 911
Query: 233 ----LKEAETRAEFAERSVAKLEKTIDDLEDELYAQ---KLKYKAISEELDH 277
L E + + + VA L++ D L +L Q ++K A + E DH
Sbjct: 912 ANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDH 963
Score = 64.7 bits (156), Expect = 9e-11
Identities = 54/294 (18%), Positives = 141/294 (47%), Gaps = 22/294 (7%)
Query: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELD- 59
++E +K+ ML+ + + A + A+ K + + + ++++M++ L+ E+E+
Sbjct: 349 LLEQKEKENSMLREEMHRRFENAPDS-AKTKALQTVIEMKDSKISSMERGLRDLEEEIQM 407
Query: 60 -KYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAE 118
K + AL + + E+ + + + ++ + +I V++EL R L KLE
Sbjct: 408 LKSNGALSTEEREEEMKQMEVYRSHSKF--MKNKIGQVKQELSRKDTELLALQTKLETLT 465
Query: 119 KAADESERGMKVI-------ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLV 171
+S++ ++V+ E RA + +++ ++L+E + + + ++ +++A +
Sbjct: 466 NQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKG 525
Query: 172 IIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTD 231
G++ ++ ++ E K + L+++++N+ L+ E Q +E +K L
Sbjct: 526 TQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQM-------SSLKERVKSLQA 578
Query: 232 KLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
+T E ++A+ E+TI+ L+++ + + EE+D+ D+ +
Sbjct: 579 DTTNTDTALTTLEEALAEKERTIERLKEQ---RDRDEREKQEEIDNYKKDLKDL 629
Score = 44.3 bits (103), Expect = 1e-04
Identities = 57/271 (21%), Positives = 109/271 (40%), Gaps = 38/271 (14%)
Query: 13 KLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKL 72
+L KE AL + E ++ + + R Q E++ MQ ++ +DEL ++ +L
Sbjct: 193 ELKKERALRKDEASKITIWKEQYRVVQEENQ--HMQMTIQALQDEL-----RIQRDLNQL 245
Query: 73 ELAEKKAADAEAEVASLNRR-IQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVI 131
+ + E VA L Q + E +R + L + LEE E + ++ +
Sbjct: 246 FQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNA- 304
Query: 132 ENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKC 191
+DE +L +++ ++K ++ +A + E R+L E + E E E +
Sbjct: 305 -----RDESIKKL--LEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKEN 357
Query: 192 SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE 251
S L EE+ N + K K +T E + ++ +E
Sbjct: 358 SMLREEMHRRFENAPD----------------------SAKTKALQTVIEMKDSKISSME 395
Query: 252 KTIDDLEDELYAQKLKYKAISEELDHALNDM 282
+ + DLE+E+ K +EE + + M
Sbjct: 396 RGLRDLEEEIQMLKSNGALSTEEREEEMKQM 426
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 78.2 bits (191), Expect = 8e-15
Identities = 58/282 (20%), Positives = 136/282 (48%), Gaps = 20/282 (7%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 62
E ++++ +M+ +E + E+ ++K E+ K+ E+E Q+K + E ++ +
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 63 EALKDAQEKLELAEKK---------------AADAEAEVASLNRRIQLV--EEELDRAQE 105
E +++ +EK+ EKK + E + R+ + + +EE+ R +E
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
Query: 106 RLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEE 165
++ +K+ + E+ E ++ E + + EEKM QE +++E + + E ++ +E+
Sbjct: 497 KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQ 556
Query: 166 VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 225
+ + E + E++ E K E EE++ ++ E + ++ +K K EE+
Sbjct: 557 ---EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEK 613
Query: 226 IKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLK 267
I+ +K++E E + E + + E+ + E+++ Q+ K
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Score = 76.6 bits (187), Expect = 2e-14
Identities = 58/228 (25%), Positives = 115/228 (50%), Gaps = 20/228 (8%)
Query: 13 KLDKENALDRAEQAEAEQKQA--EERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQE 70
K+ ++ + R E+ EQ++ EE+ ++ ED++ ++K++ E+++ + E +++ +E
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 71 KLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKV 130
K + E+K E ++ +IQ EE++ R QE +K+ E E+ E E M
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQEEKI-REQE------EKIREQEEMTQEQEEKMGE 651
Query: 131 IENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESK 190
E + + EEKM+ QE + + E ++K E K+ E ++ EE+ E K
Sbjct: 652 QEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 711
Query: 191 CSELEEELKNVTNNLKSLEAQAEKYSQKEDK-YEEEIKILTDKLKEAE 237
E EE+ ++ Q EK ++E+K +E+E+++ + K E
Sbjct: 712 MCEQEEK----------MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 75.9 bits (185), Expect = 4e-14
Identities = 61/272 (22%), Positives = 136/272 (50%), Gaps = 11/272 (4%)
Query: 1 MMEAIKKKMQMLKLDKENAL---DRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDE 57
M E K + Q K +E + ++ ++ EA+ + EE+ ++ E+++ +KK+ E++
Sbjct: 400 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
Query: 58 LDKY----SEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQK 113
+ + E + QE++ E+K + E E+ ++ EE++ + +E++ +K
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQE-EIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Query: 114 LEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVII 173
+ E E+ E E M E + ++++E+M +E ++ E + I EE R+ +E K+
Sbjct: 519 IREQEEKIREQEEKMWRQEEK-IREQEEMWREEEKMHEQEKIWEEEKRQEQE--DKMWRQ 575
Query: 174 EGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKL 233
E + EE+ E K E EE+ + + E + + +K + EE+I+ +K+
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Query: 234 KEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
+E E + E + + E+ + + E+++ Q+
Sbjct: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Score = 75.1 bits (183), Expect = 7e-14
Identities = 53/249 (21%), Positives = 122/249 (48%), Gaps = 12/249 (4%)
Query: 24 EQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEK------ 77
EQ E +KQ E+ +Q E+++ ++K++ E+++ + E +++ +E EK
Sbjct: 500 EQEEKIRKQEEKVWRQ-EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 78 -----KAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIE 132
K + E ++ +I+ EE++ R +E++ +K +E E+ + E ++ E
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 133 NRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCS 192
+ + EEK+ QE +++E + + +E + K E K+ E ++ EE E K
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 193 ELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEK 252
E E++++ ++ E ++ +K + EE++ +K++E E + E + + E
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 253 TIDDLEDEL 261
+ E+++
Sbjct: 739 RLRQQEEKM 747
Score = 72.4 bits (176), Expect = 4e-13
Identities = 66/280 (23%), Positives = 138/280 (49%), Gaps = 11/280 (3%)
Query: 1 MMEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDK 60
++E+ K ++Q+ + + L+RA+ Q+Q + + L EL ++ KL+ +E +
Sbjct: 232 LVESEKSEIQLNVKELKRKLERAKLL-LPQQQLQAEADHLGKELQSVSAKLQAQVEENEL 290
Query: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 120
++ + +EK+ E+K + E ++ +I+ EE++ +E++ + + E E+
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350
Query: 121 ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERT 180
E M E + + EE M +E +++ + + E + K E+ K+ E E+
Sbjct: 351 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 410
Query: 181 EERAELAESKCSELE---EELKNVTNNLKSLEAQAEKYSQKEDK-YEEEIKI-LTDKLKE 235
E+R E E K E E E+ + + + Q EK ++E K + +E KI +K++E
Sbjct: 411 EKRQE--EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
Query: 236 AETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
E R E + + + E+ I + ++E++ QK K E++
Sbjct: 469 EEKRQE--QEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKI 505
Score = 69.3 bits (168), Expect = 4e-12
Identities = 66/250 (26%), Positives = 123/250 (49%), Gaps = 27/250 (10%)
Query: 38 KQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAE----KKAADAEA-----EVAS 88
++L+++ A +Q+KL+ E E + +K+ + KLE A+ ++ AEA E+ S
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 89 LNRRIQLVEEELD-------RAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEK 141
++ ++Q EE + + +E++ +K++E E+ E E ++ E + + EEK
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 142 MELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNV 201
M QE + E EE R+ EE+ + E + R EE E K EE +
Sbjct: 337 MRRQEEMMWE----KEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKMRRQEEMMWEK 389
Query: 202 TNNLKSLEA---QAEKYSQKEDKYEEEIKIL-TDKLKEAETRAEFAERSVAKLEKTIDDL 257
++ LE + EK ++E+K +EE KI +K +E E + E + + E+ I +
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449
Query: 258 EDELYAQKLK 267
E +++ Q+ K
Sbjct: 450 EKKMWRQEEK 459
Score = 67.8 bits (164), Expect = 1e-11
Identities = 47/215 (21%), Positives = 105/215 (48%), Gaps = 4/215 (1%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSK--QLEDELAAMQKKLKGTEDELDK 60
E I+++ +M + +E + E+ E+K+ E+ K + E+++ ++K+ E+++ +
Sbjct: 538 EKIREQEEMWR--EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595
Query: 61 YSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKA 120
E ++ +EK+ E+K + E ++ +I+ EE++ +E +K+ E E+
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 121 ADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERT 180
E E M+ E + EEK+ QE +++E + E + +E K+ E +
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 715
Query: 181 EERAELAESKCSELEEELKNVTNNLKSLEAQAEKY 215
EE+ + E K EE++ L+ E + +++
Sbjct: 716 EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 67.4 bits (163), Expect = 1e-11
Identities = 58/298 (19%), Positives = 144/298 (48%), Gaps = 29/298 (9%)
Query: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQK---QAEERSKQLEDELAAMQKKLKGTEDELD 59
E I+++ + ++ +E ++ E+ +++ + EE+ ++ E+ + ++K++ E+ +
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 60 KYSEALKDAQEKLELAEK-----KAADAEAEVASLNRRIQLV------EEELDRAQERLA 108
+ E +++ +EK+ EK + E ++ +R + EE++ +E++
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
Query: 109 TALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVAR 168
+K+ E+ E E K+ E +++E+M QE ++ E + I + ++ +E+
Sbjct: 448 EQEKKMWRQEEKIHEQE---KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ-EE 503
Query: 169 KLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEA---------QAEKYSQKE 219
K+ E + R EE+ E K E EE++ ++ E + EK ++E
Sbjct: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
Query: 220 DKYEEEIKI--LTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
+ E+E K+ +K++E E + E + + E+ + E++++ Q+ K + E++
Sbjct: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Score = 31.2 bits (69), Expect = 1.1
Identities = 46/235 (19%), Positives = 98/235 (41%), Gaps = 53/235 (22%)
Query: 83 EAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRA------L 136
E E + ++ + + EL+ + + E + A S+ +K +E A L
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 137 KDEEKM--ELQEIQLKEAKHIAEEADRKYEEVAR-------------------------- 168
D K EL++ L ++ADR EE+ +
Sbjct: 168 HDSWKFAGELEQA-LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKL 226
Query: 169 --KLVIIEG----------DLERTEERAEL------AESKCSELEEELKNVTNNLKSLEA 210
KL ++E +L+R ERA+L +++ L +EL++V+ L++
Sbjct: 227 QEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 286
Query: 211 QAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
+ E +++ + EE++ +K++E E + + E + + E+ I + E+++ Q+
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 78.2 bits (191), Expect = 8e-15
Identities = 72/294 (24%), Positives = 138/294 (46%), Gaps = 28/294 (9%)
Query: 3 EAIK--KKMQMLKLDKENALDRAEQAEAE----QKQAEERSKQLEDELAAMQKKLKGTED 56
EAIK +K+Q D + L+ A + E K+ E+++K LE +L +Q+ L E
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE- 1700
Query: 57 ELDKYSEALKDAQ-EKLELAEKKAAD------AEAEVASLNRRIQLVEEELDRAQERLAT 109
A K A EK ELAE+ A+ + E L RI +EEEL+ Q +
Sbjct: 1701 ------RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1754
Query: 110 ALQKLEEAEKAADESERGMKVIENRALKDE---EKMELQEIQLKEAKHIAEEADR-KYEE 165
++ +A + A++ + + A K+E +++E Q +L+ H E A + K++
Sbjct: 1755 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS 1814
Query: 166 ----VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK 221
+ K+ +E +E+ + A + +++LK + ++ AE+Y ++ +K
Sbjct: 1815 TIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1874
Query: 222 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
+K L +L+EAE ++ + KL++ +D+ + A + A+ +L
Sbjct: 1875 GNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Score = 75.5 bits (184), Expect = 5e-14
Identities = 62/252 (24%), Positives = 122/252 (48%), Gaps = 16/252 (6%)
Query: 43 ELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDR 102
++ +++++ EDEL K E + A+ +L+ E+K + E L ++Q E
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 103 AQE---RLATALQKLEE-----AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKH 154
A+E RLA Q+LEE + +E +RG ++ R ++ ++L+E QL+E +
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEA 964
Query: 155 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 214
++ + K+ +E ++ +++ + LEE + ++T NL E +A+
Sbjct: 965 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1024
Query: 215 YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE-------KTIDDLEDELYAQKLK 267
++ ++K+E I L +LK+ E + E+ KLE + I DL+ ++ K++
Sbjct: 1025 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1084
Query: 268 YKAISEELDHAL 279
EEL AL
Sbjct: 1085 LAKKEEELQAAL 1096
Score = 70.1 bits (170), Expect = 2e-12
Identities = 68/273 (24%), Positives = 131/273 (47%), Gaps = 18/273 (6%)
Query: 5 IKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEA 64
++ MQ LK E L +A +Q EE+ +QL+ +L + +L EDE + A
Sbjct: 1565 LEVNMQALKGQFERDL------QARDEQNEEKRRQLQRQLHEYETEL---EDE--RKQRA 1613
Query: 65 LKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 124
L A +K + K + +A+ A R + ++L + Q ++ ++LE+A + DE
Sbjct: 1614 LAAAAKKKLEGDLKDLELQADSAIKGREEAI--KQLRKLQAQMKDFQRELEDARASRDEI 1671
Query: 125 ERGMKVIENRALKDE-EKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEER 183
K E +A E + M+LQE L A+ ++AD + EE+A +L ++
Sbjct: 1672 FATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDE 1730
Query: 184 AELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 243
E++ ++LEEEL+ N++++ + K +Q+ ++ E+ ++ E+ +
Sbjct: 1731 KRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL 1790
Query: 244 ERSVAKLEKTIDDLEDELYAQKLKYKAISEELD 276
ER +L + ++E A K K+K+ L+
Sbjct: 1791 ERQNKELRSKLHEMEG---AVKSKFKSTIAALE 1820
Score = 65.1 bits (157), Expect = 7e-11
Identities = 64/289 (22%), Positives = 142/289 (49%), Gaps = 37/289 (12%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEA- 64
+++MQ + + + +R ++AE E K+ E++ QL +E +Q++L+ E + Y+EA
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 907
Query: 65 ----------------LKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLA 108
L + + +LE E + +AE + +++ +EE+L+ +E A
Sbjct: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE--EEEAA 965
Query: 109 TALQKLEE--AEKAADESERGMKVIENRALKDEEKMELQEIQLKE-AKHIAEEADR---- 161
+LE+ AE + E + V++++ K ++ +L E ++ + ++AEE ++
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 162 -----KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYS 216
K+E + +L E L++ E+ + E +LE + + + L+AQ +
Sbjct: 1026 TKLKNKHESMISEL---EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1082
Query: 217 QKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
+ K EEE++ +L + + A + + +LE I DL+++L +++
Sbjct: 1083 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1131
Score = 65.1 bits (157), Expect = 7e-11
Identities = 70/304 (23%), Positives = 143/304 (47%), Gaps = 37/304 (12%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEER----SKQLEDELAAMQK-------- 49
+E I +M+ +L++E DR +Q +AE+K+ ++ +QLE+E AA QK
Sbjct: 920 LEEILHEMEA-RLEEEE--DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 976
Query: 50 --KLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERL 107
K+K EDE+ + ++ +L E++ +D +A + + + + ++ + +
Sbjct: 977 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1036
Query: 108 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 167
+ +L++ EK+ E E+ + +E A E++ + Q+ E K + +K EE+
Sbjct: 1037 SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK---MQLAKKEEELQ 1093
Query: 168 RKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIK 227
L ++ ++ + A K ELE + ++ +L S A K +++ EE++
Sbjct: 1094 AALARLDDEIAQKNN----ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 228 ILTDKLKEA--------ETRAEFAERSVAKLEKTIDD----LEDELYAQKLKYKAISEEL 275
L +L++ E RA+ E+ V L+K +D+ E ++ + K+ EEL
Sbjct: 1150 ALKTELEDTLDSTATQQELRAK-REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1208
Query: 276 DHAL 279
L
Sbjct: 1209 TEQL 1212
Score = 64.3 bits (155), Expect = 1e-10
Identities = 54/256 (21%), Positives = 117/256 (45%), Gaps = 32/256 (12%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELA-------AMQKKLKGTEDEL 58
+KK + L+ D + AE +KQA+ ++L +ELA A+Q + + E +
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
Query: 59 DKYSEALKDAQEKLELAEKKAADAEAEVASLNRRI----------QLVEEELDRAQERLA 108
+ E L++ Q +E + A + L+ + + ++L+R + L
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
Query: 109 TALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVAR 168
+ L ++E A K+ +S + +E + + EE++E + + + A ++ D+K +E+
Sbjct: 1799 SKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI-- 1854
Query: 169 KLVIIEGDLERTEERAELAES----------KCSELEEELKNVTNNLKSLEAQAEKYSQK 218
L+ +E + + E+ E AE + E EEE + + N + L+ + ++ ++
Sbjct: 1855 -LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1913
Query: 219 EDKYEEEIKILTDKLK 234
+ E+ L KL+
Sbjct: 1914 NEAMGREVNALKSKLR 1929
Score = 62.4 bits (150), Expect = 4e-10
Identities = 61/285 (21%), Positives = 130/285 (45%), Gaps = 21/285 (7%)
Query: 7 KKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALK 66
KK++ L+ + + + A + +AE++ + L +EL A++ +L+ T D E L+
Sbjct: 1111 KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE-LR 1169
Query: 67 DAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 126
+E+ KKA D E S ++Q + ++ +A E L L++ + A+ D++++
Sbjct: 1170 AKREQEVTVLKKALDEETR--SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
Query: 127 GM-----------KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEG 175
+ +V+ + E K + E Q++E + + +R E+ K+ ++
Sbjct: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 176 DLERTEERAELAESKCSELEEELKNVTNNLKSLEA-------QAEKYSQKEDKYEEEIKI 228
++E AE K +L +++ ++++ L+ + Q S K + EEE
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 229 LTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISE 273
L D+L E + ER ++ L + D + +L +A+ E
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392
Score = 62.4 bits (150), Expect = 4e-10
Identities = 65/298 (21%), Positives = 136/298 (45%), Gaps = 42/298 (14%)
Query: 7 KKMQMLKLDKENALDR-AEQAEAEQKQAEERS---KQLEDELAAMQKKLKGTEDELDKYS 62
++++ LK + E+ LD A Q E K+ +E + K L++E + + ++ ++ K++
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV---QEMRQKHA 1202
Query: 63 EALKDAQEKLE--------------LAEKKAADAEAEVASLNRRIQLVEEELDRAQERLA 108
+A+++ E+LE EK+ AD E+ L + Q VE + + + ++
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
Query: 109 TALQKLEEAEKAAD-------------ESERGM-KVIENRALKDEEKMELQEIQLKEAKH 154
K + E+A ES GM E +A+K + + QL++ +
Sbjct: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Query: 155 IAEEADRKYEEVARKLVIIEGD-------LERTEERAELAESKCSELEEELKNVTNNLKS 207
+ +E R+ V+ KL +E + L+ E + E S L +L + L+
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Query: 208 LEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
+ E + + ++++EI+ LT + +E + E++ +L++ +DDL +L Q+
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Score = 58.9 bits (141), Expect = 5e-09
Identities = 66/334 (19%), Positives = 139/334 (41%), Gaps = 55/334 (16%)
Query: 3 EAIKKKMQMLKLDKENALDRAE-----------QAEAEQKQAEERSKQLEDELAAMQKKL 51
EA ++K+Q+ K+ E + + E + E+K EER L LA ++K
Sbjct: 963 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1022
Query: 52 KGTEDELDKYSEALKDAQEKLELAEKK--------------AADAEAEVASLNRRIQLVE 97
K +K+ + + + +L+ EK A+D ++A L +I ++
Sbjct: 1023 KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1082
Query: 98 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 157
+L + +E L AL +L++ + + + ++ +E +E ++ + + A++ AE
Sbjct: 1083 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE----RAARNKAE 1138
Query: 158 EADRKY-EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYS 216
+ R EE+ +E L+ T + EL + E+ K + +S EAQ ++
Sbjct: 1139 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1198
Query: 217 QKEDKYEEEIKILTDKLKEAETR------------AEFA-------------ERSVAKLE 251
QK + EE+ ++ K A+ A+ A E KLE
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 252 KTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
+ +L+ + + +++++ N++ S+
Sbjct: 1259 AQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1292
Score = 48.5 bits (114), Expect = 7e-06
Identities = 76/340 (22%), Positives = 135/340 (39%), Gaps = 81/340 (23%)
Query: 16 KENALDRAEQAEAEQKQAEERSKQLEDELAAMQ-----------------KKLKGTEDEL 58
K N + Q E E+ ++ QL++E+ A Q KKL+ +
Sbjct: 1331 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1387
Query: 59 DKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRA------QERLATALQ 112
+ E K Q+++E ++ + A L + +++ELD Q +L + L+
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
Query: 113 KLEE------------AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 160
K + + K ADE +R E A + E K L+EA EE +
Sbjct: 1448 KKQRKFDQLLAEEKNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELE 1503
Query: 161 R--------------KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTN--- 203
R ++V + + +E E + E +++ ELE+EL+ +
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1563
Query: 204 ----NLKSLEAQAEKYSQ-KEDKYEEEIKILTDKLKEAETRAE-------FAERSVAKLE 251
N+++L+ Q E+ Q ++++ EE+ + L +L E ET E A + KLE
Sbjct: 1564 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623
Query: 252 KTIDDLE----------DELYAQKLKYKAISEELDHALND 281
+ DLE +E Q K +A ++ L D
Sbjct: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663
Score = 46.2 bits (108), Expect = 3e-05
Identities = 42/189 (22%), Positives = 91/189 (48%), Gaps = 17/189 (8%)
Query: 1 MMEAIKKKMQMLK-LDKENALDR--AEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDE 57
M + ++K Q + L E A +R A++ E+ ++Q E ++K+L +L M+ +K
Sbjct: 1755 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS---- 1810
Query: 58 LDKYSEALKDAQEKL----ELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQK 113
K+ + + K+ E E++A + +A SL ++ + ++E L + ++ A Q
Sbjct: 1811 --KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1868
Query: 114 LEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVII 173
E+AEK +K ++ + + EE+ + ++ + +EA E + R++ +
Sbjct: 1869 KEQAEKG----NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
Query: 174 EGDLERTEE 182
+ L R E
Sbjct: 1925 KSKLRRGNE 1933
Score = 45.8 bits (107), Expect = 4e-05
Identities = 63/306 (20%), Positives = 130/306 (42%), Gaps = 39/306 (12%)
Query: 2 MEAIKKKMQMLKLDKENAL----DRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDE 57
+EA +++Q D E A D+ + + E + + E + + K + +
Sbjct: 1257 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1316
Query: 58 LDKYSEAL-KDAQEKLELAEK------------KAADAEAEV-ASLNRRIQLVEEELDRA 103
L E L ++ ++KL ++ K D E E +L R I + +L +
Sbjct: 1317 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS 1376
Query: 104 QERL---ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 160
+++L A+ ++ LEE +K R K IEN + EEK + K + +E D
Sbjct: 1377 KKKLQDFASTVEALEEGKK------RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 161 RKYEEVARKLVIIEGDLERTEERAE--LAESK---------CSELEEELKNVTNNLKSLE 209
++ + ++ +LE+ + + + LAE K E E + SL
Sbjct: 1431 DLVVDLDNQRQLV-SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1489
Query: 210 AQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYK 269
E+ + +++ E K+L ++++ + + ++V +LEK+ LE ++ K + +
Sbjct: 1490 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549
Query: 270 AISEEL 275
+ +EL
Sbjct: 1550 ELEDEL 1555
Score = 45.1 bits (105), Expect = 7e-05
Identities = 33/139 (23%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Query: 27 EAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEV 86
EA+ Q EE+ +Q E A K LK + +L + ++D ++ E +++A A V
Sbjct: 1820 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARV 1879
Query: 87 ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQE 146
L R+++ EEE R ++L+EA ++ + R + ++++ + E +
Sbjct: 1880 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPS 1939
Query: 147 IQLKEAKHIAEEADRKYEE 165
+ + + E AD EE
Sbjct: 1940 -RRSGGRRVIENADGSEEE 1957
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 78.2 bits (191), Expect = 8e-15
Identities = 72/294 (24%), Positives = 138/294 (46%), Gaps = 28/294 (9%)
Query: 3 EAIK--KKMQMLKLDKENALDRAEQAEAE----QKQAEERSKQLEDELAAMQKKLKGTED 56
EAIK +K+Q D + L+ A + E K+ E+++K LE +L +Q+ L E
Sbjct: 1649 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE- 1707
Query: 57 ELDKYSEALKDAQ-EKLELAEKKAAD------AEAEVASLNRRIQLVEEELDRAQERLAT 109
A K A EK ELAE+ A+ + E L RI +EEEL+ Q +
Sbjct: 1708 ------RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1761
Query: 110 ALQKLEEAEKAADESERGMKVIENRALKDE---EKMELQEIQLKEAKHIAEEADR-KYEE 165
++ +A + A++ + + A K+E +++E Q +L+ H E A + K++
Sbjct: 1762 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS 1821
Query: 166 ----VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK 221
+ K+ +E +E+ + A + +++LK + ++ AE+Y ++ +K
Sbjct: 1822 TIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1881
Query: 222 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
+K L +L+EAE ++ + KL++ +D+ + A + A+ +L
Sbjct: 1882 GNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Score = 75.5 bits (184), Expect = 5e-14
Identities = 62/252 (24%), Positives = 122/252 (48%), Gaps = 16/252 (6%)
Query: 43 ELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDR 102
++ +++++ EDEL K E + A+ +L+ E+K + E L ++Q E
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 103 AQE---RLATALQKLEE-----AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKH 154
A+E RLA Q+LEE + +E +RG ++ R ++ ++L+E QL+E +
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEA 971
Query: 155 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 214
++ + K+ +E ++ +++ + LEE + ++T NL E +A+
Sbjct: 972 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1031
Query: 215 YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE-------KTIDDLEDELYAQKLK 267
++ ++K+E I L +LK+ E + E+ KLE + I DL+ ++ K++
Sbjct: 1032 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1091
Query: 268 YKAISEELDHAL 279
EEL AL
Sbjct: 1092 LAKKEEELQAAL 1103
Score = 70.1 bits (170), Expect = 2e-12
Identities = 68/273 (24%), Positives = 131/273 (47%), Gaps = 18/273 (6%)
Query: 5 IKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEA 64
++ MQ LK E L +A +Q EE+ +QL+ +L + +L EDE + A
Sbjct: 1572 LEVNMQALKGQFERDL------QARDEQNEEKRRQLQRQLHEYETEL---EDE--RKQRA 1620
Query: 65 LKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 124
L A +K + K + +A+ A R + ++L + Q ++ ++LE+A + DE
Sbjct: 1621 LAAAAKKKLEGDLKDLELQADSAIKGREEAI--KQLRKLQAQMKDFQRELEDARASRDEI 1678
Query: 125 ERGMKVIENRALKDE-EKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEER 183
K E +A E + M+LQE L A+ ++AD + EE+A +L ++
Sbjct: 1679 FATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDE 1737
Query: 184 AELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 243
E++ ++LEEEL+ N++++ + K +Q+ ++ E+ ++ E+ +
Sbjct: 1738 KRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL 1797
Query: 244 ERSVAKLEKTIDDLEDELYAQKLKYKAISEELD 276
ER +L + ++E A K K+K+ L+
Sbjct: 1798 ERQNKELRSKLHEMEG---AVKSKFKSTIAALE 1827
Score = 65.1 bits (157), Expect = 7e-11
Identities = 64/289 (22%), Positives = 142/289 (49%), Gaps = 37/289 (12%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEA- 64
+++MQ + + + +R ++AE E K+ E++ QL +E +Q++L+ E + Y+EA
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 914
Query: 65 ----------------LKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLA 108
L + + +LE E + +AE + +++ +EE+L+ +E A
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE--EEEAA 972
Query: 109 TALQKLEE--AEKAADESERGMKVIENRALKDEEKMELQEIQLKE-AKHIAEEADR---- 161
+LE+ AE + E + V++++ K ++ +L E ++ + ++AEE ++
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 162 -----KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYS 216
K+E + +L E L++ E+ + E +LE + + + L+AQ +
Sbjct: 1033 TKLKNKHESMISEL---EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1089
Query: 217 QKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
+ K EEE++ +L + + A + + +LE I DL+++L +++
Sbjct: 1090 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1138
Score = 65.1 bits (157), Expect = 7e-11
Identities = 70/304 (23%), Positives = 143/304 (47%), Gaps = 37/304 (12%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEER----SKQLEDELAAMQK-------- 49
+E I +M+ +L++E DR +Q +AE+K+ ++ +QLE+E AA QK
Sbjct: 927 LEEILHEMEA-RLEEEE--DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 983
Query: 50 --KLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERL 107
K+K EDE+ + ++ +L E++ +D +A + + + + ++ + +
Sbjct: 984 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1043
Query: 108 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 167
+ +L++ EK+ E E+ + +E A E++ + Q+ E K + +K EE+
Sbjct: 1044 SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK---MQLAKKEEELQ 1100
Query: 168 RKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIK 227
L ++ ++ + A K ELE + ++ +L S A K +++ EE++
Sbjct: 1101 AALARLDDEIAQKNN----ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 228 ILTDKLKEA--------ETRAEFAERSVAKLEKTIDD----LEDELYAQKLKYKAISEEL 275
L +L++ E RA+ E+ V L+K +D+ E ++ + K+ EEL
Sbjct: 1157 ALKTELEDTLDSTATQQELRAK-REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1215
Query: 276 DHAL 279
L
Sbjct: 1216 TEQL 1219
Score = 64.3 bits (155), Expect = 1e-10
Identities = 54/256 (21%), Positives = 117/256 (45%), Gaps = 32/256 (12%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELA-------AMQKKLKGTEDEL 58
+KK + L+ D + AE +KQA+ ++L +ELA A+Q + + E +
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745
Query: 59 DKYSEALKDAQEKLELAEKKAADAEAEVASLNRRI----------QLVEEELDRAQERLA 108
+ E L++ Q +E + A + L+ + + ++L+R + L
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805
Query: 109 TALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVAR 168
+ L ++E A K+ +S + +E + + EE++E + + + A ++ D+K +E+
Sbjct: 1806 SKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI-- 1861
Query: 169 KLVIIEGDLERTEERAELAES----------KCSELEEELKNVTNNLKSLEAQAEKYSQK 218
L+ +E + + E+ E AE + E EEE + + N + L+ + ++ ++
Sbjct: 1862 -LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1920
Query: 219 EDKYEEEIKILTDKLK 234
+ E+ L KL+
Sbjct: 1921 NEAMGREVNALKSKLR 1936
Score = 62.4 bits (150), Expect = 4e-10
Identities = 61/285 (21%), Positives = 130/285 (45%), Gaps = 21/285 (7%)
Query: 7 KKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALK 66
KK++ L+ + + + A + +AE++ + L +EL A++ +L+ T D E L+
Sbjct: 1118 KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE-LR 1176
Query: 67 DAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 126
+E+ KKA D E S ++Q + ++ +A E L L++ + A+ D++++
Sbjct: 1177 AKREQEVTVLKKALDEETR--SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1234
Query: 127 GM-----------KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEG 175
+ +V+ + E K + E Q++E + + +R E+ K+ ++
Sbjct: 1235 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 176 DLERTEERAELAESKCSELEEELKNVTNNLKSLEA-------QAEKYSQKEDKYEEEIKI 228
++E AE K +L +++ ++++ L+ + Q S K + EEE
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 229 LTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISE 273
L D+L E + ER ++ L + D + +L +A+ E
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399
Score = 62.4 bits (150), Expect = 4e-10
Identities = 65/298 (21%), Positives = 136/298 (45%), Gaps = 42/298 (14%)
Query: 7 KKMQMLKLDKENALDR-AEQAEAEQKQAEERS---KQLEDELAAMQKKLKGTEDELDKYS 62
++++ LK + E+ LD A Q E K+ +E + K L++E + + ++ ++ K++
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV---QEMRQKHA 1209
Query: 63 EALKDAQEKLE--------------LAEKKAADAEAEVASLNRRIQLVEEELDRAQERLA 108
+A+++ E+LE EK+ AD E+ L + Q VE + + + ++
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1269
Query: 109 TALQKLEEAEKAAD-------------ESERGM-KVIENRALKDEEKMELQEIQLKEAKH 154
K + E+A ES GM E +A+K + + QL++ +
Sbjct: 1270 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329
Query: 155 IAEEADRKYEEVARKLVIIEGD-------LERTEERAELAESKCSELEEELKNVTNNLKS 207
+ +E R+ V+ KL +E + L+ E + E S L +L + L+
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Query: 208 LEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
+ E + + ++++EI+ LT + +E + E++ +L++ +DDL +L Q+
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1447
Score = 58.9 bits (141), Expect = 5e-09
Identities = 66/334 (19%), Positives = 139/334 (41%), Gaps = 55/334 (16%)
Query: 3 EAIKKKMQMLKLDKENALDRAE-----------QAEAEQKQAEERSKQLEDELAAMQKKL 51
EA ++K+Q+ K+ E + + E + E+K EER L LA ++K
Sbjct: 970 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1029
Query: 52 KGTEDELDKYSEALKDAQEKLELAEKK--------------AADAEAEVASLNRRIQLVE 97
K +K+ + + + +L+ EK A+D ++A L +I ++
Sbjct: 1030 KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1089
Query: 98 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 157
+L + +E L AL +L++ + + + ++ +E +E ++ + + A++ AE
Sbjct: 1090 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE----RAARNKAE 1145
Query: 158 EADRKY-EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYS 216
+ R EE+ +E L+ T + EL + E+ K + +S EAQ ++
Sbjct: 1146 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1205
Query: 217 QKEDKYEEEIKILTDKLKEAETR------------AEFA-------------ERSVAKLE 251
QK + EE+ ++ K A+ A+ A E KLE
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 252 KTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
+ +L+ + + +++++ N++ S+
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Score = 48.5 bits (114), Expect = 7e-06
Identities = 76/340 (22%), Positives = 135/340 (39%), Gaps = 81/340 (23%)
Query: 16 KENALDRAEQAEAEQKQAEERSKQLEDELAAMQ-----------------KKLKGTEDEL 58
K N + Q E E+ ++ QL++E+ A Q KKL+ +
Sbjct: 1338 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1394
Query: 59 DKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRA------QERLATALQ 112
+ E K Q+++E ++ + A L + +++ELD Q +L + L+
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1454
Query: 113 KLEE------------AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 160
K + + K ADE +R E A + E K L+EA EE +
Sbjct: 1455 KKQRKFDQLLAEEKNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELE 1510
Query: 161 R--------------KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTN--- 203
R ++V + + +E E + E +++ ELE+EL+ +
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1570
Query: 204 ----NLKSLEAQAEKYSQ-KEDKYEEEIKILTDKLKEAETRAE-------FAERSVAKLE 251
N+++L+ Q E+ Q ++++ EE+ + L +L E ET E A + KLE
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630
Query: 252 KTIDDLE----------DELYAQKLKYKAISEELDHALND 281
+ DLE +E Q K +A ++ L D
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670
Score = 46.2 bits (108), Expect = 3e-05
Identities = 42/189 (22%), Positives = 91/189 (48%), Gaps = 17/189 (8%)
Query: 1 MMEAIKKKMQMLK-LDKENALDR--AEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDE 57
M + ++K Q + L E A +R A++ E+ ++Q E ++K+L +L M+ +K
Sbjct: 1762 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS---- 1817
Query: 58 LDKYSEALKDAQEKL----ELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQK 113
K+ + + K+ E E++A + +A SL ++ + ++E L + ++ A Q
Sbjct: 1818 --KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1875
Query: 114 LEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVII 173
E+AEK +K ++ + + EE+ + ++ + +EA E + R++ +
Sbjct: 1876 KEQAEKG----NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1931
Query: 174 EGDLERTEE 182
+ L R E
Sbjct: 1932 KSKLRRGNE 1940
Score = 45.8 bits (107), Expect = 4e-05
Identities = 63/306 (20%), Positives = 130/306 (42%), Gaps = 39/306 (12%)
Query: 2 MEAIKKKMQMLKLDKENAL----DRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDE 57
+EA +++Q D E A D+ + + E + + E + + K + +
Sbjct: 1264 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1323
Query: 58 LDKYSEAL-KDAQEKLELAEK------------KAADAEAEV-ASLNRRIQLVEEELDRA 103
L E L ++ ++KL ++ K D E E +L R I + +L +
Sbjct: 1324 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS 1383
Query: 104 QERL---ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 160
+++L A+ ++ LEE +K R K IEN + EEK + K + +E D
Sbjct: 1384 KKKLQDFASTVEALEEGKK------RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 161 RKYEEVARKLVIIEGDLERTEERAE--LAESK---------CSELEEELKNVTNNLKSLE 209
++ + ++ +LE+ + + + LAE K E E + SL
Sbjct: 1438 DLVVDLDNQRQLV-SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1496
Query: 210 AQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYK 269
E+ + +++ E K+L ++++ + + ++V +LEK+ LE ++ K + +
Sbjct: 1497 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
Query: 270 AISEEL 275
+ +EL
Sbjct: 1557 ELEDEL 1562
Score = 45.1 bits (105), Expect = 7e-05
Identities = 33/139 (23%), Positives = 65/139 (46%), Gaps = 1/139 (0%)
Query: 27 EAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEV 86
EA+ Q EE+ +Q E A K LK + +L + ++D ++ E +++A A V
Sbjct: 1827 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARV 1886
Query: 87 ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQE 146
L R+++ EEE R ++L+EA ++ + R + ++++ + E +
Sbjct: 1887 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPS 1946
Query: 147 IQLKEAKHIAEEADRKYEE 165
+ + + E AD EE
Sbjct: 1947 -RRSGGRRVIENADGSEEE 1964
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 78.2 bits (191), Expect = 8e-15
Identities = 72/294 (24%), Positives = 138/294 (46%), Gaps = 28/294 (9%)
Query: 3 EAIK--KKMQMLKLDKENALDRAEQAEAE----QKQAEERSKQLEDELAAMQKKLKGTED 56
EAIK +K+Q D + L+ A + E K+ E+++K LE +L +Q+ L E
Sbjct: 1649 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE- 1707
Query: 57 ELDKYSEALKDAQ-EKLELAEKKAAD------AEAEVASLNRRIQLVEEELDRAQERLAT 109
A K A EK ELAE+ A+ + E L RI +EEEL+ Q +
Sbjct: 1708 ------RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1761
Query: 110 ALQKLEEAEKAADESERGMKVIENRALKDE---EKMELQEIQLKEAKHIAEEADR-KYEE 165
++ +A + A++ + + A K+E +++E Q +L+ H E A + K++
Sbjct: 1762 MSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS 1821
Query: 166 ----VARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDK 221
+ K+ +E +E+ + A + +++LK + ++ AE+Y ++ +K
Sbjct: 1822 TIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEK 1881
Query: 222 YEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEEL 275
+K L +L+EAE ++ + KL++ +D+ + A + A+ +L
Sbjct: 1882 GNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Score = 75.5 bits (184), Expect = 5e-14
Identities = 62/252 (24%), Positives = 122/252 (48%), Gaps = 16/252 (6%)
Query: 43 ELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDR 102
++ +++++ EDEL K E + A+ +L+ E+K + E L ++Q E
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 103 AQE---RLATALQKLEE-----AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKH 154
A+E RLA Q+LEE + +E +RG ++ R ++ ++L+E QL+E +
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE-QLEEEEA 971
Query: 155 IAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEK 214
++ + K+ +E ++ +++ + LEE + ++T NL E +A+
Sbjct: 972 ARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN 1031
Query: 215 YSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLE-------KTIDDLEDELYAQKLK 267
++ ++K+E I L +LK+ E + E+ KLE + I DL+ ++ K++
Sbjct: 1032 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1091
Query: 268 YKAISEELDHAL 279
EEL AL
Sbjct: 1092 LAKKEEELQAAL 1103
Score = 70.1 bits (170), Expect = 2e-12
Identities = 68/273 (24%), Positives = 131/273 (47%), Gaps = 18/273 (6%)
Query: 5 IKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEA 64
++ MQ LK E L +A +Q EE+ +QL+ +L + +L EDE + A
Sbjct: 1572 LEVNMQALKGQFERDL------QARDEQNEEKRRQLQRQLHEYETEL---EDE--RKQRA 1620
Query: 65 LKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES 124
L A +K + K + +A+ A R + ++L + Q ++ ++LE+A + DE
Sbjct: 1621 LAAAAKKKLEGDLKDLELQADSAIKGREEAI--KQLRKLQAQMKDFQRELEDARASRDEI 1678
Query: 125 ERGMKVIENRALKDE-EKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEER 183
K E +A E + M+LQE L A+ ++AD + EE+A +L ++
Sbjct: 1679 FATAKENEKKAKSLEADLMQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDE 1737
Query: 184 AELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFA 243
E++ ++LEEEL+ N++++ + K +Q+ ++ E+ ++ E+ +
Sbjct: 1738 KRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL 1797
Query: 244 ERSVAKLEKTIDDLEDELYAQKLKYKAISEELD 276
ER +L + ++E A K K+K+ L+
Sbjct: 1798 ERQNKELRSKLHEMEG---AVKSKFKSTIAALE 1827
Score = 65.1 bits (157), Expect = 7e-11
Identities = 64/289 (22%), Positives = 142/289 (49%), Gaps = 37/289 (12%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEA- 64
+++MQ + + + +R ++AE E K+ E++ QL +E +Q++L+ E + Y+EA
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA---ETELYAEAE 914
Query: 65 ----------------LKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLA 108
L + + +LE E + +AE + +++ +EE+L+ +E A
Sbjct: 915 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE--EEEAA 972
Query: 109 TALQKLEE--AEKAADESERGMKVIENRALKDEEKMELQEIQLKE-AKHIAEEADR---- 161
+LE+ AE + E + V++++ K ++ +L E ++ + ++AEE ++
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032
Query: 162 -----KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYS 216
K+E + +L E L++ E+ + E +LE + + + L+AQ +
Sbjct: 1033 TKLKNKHESMISEL---EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1089
Query: 217 QKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
+ K EEE++ +L + + A + + +LE I DL+++L +++
Sbjct: 1090 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1138
Score = 65.1 bits (157), Expect = 7e-11
Identities = 70/304 (23%), Positives = 143/304 (47%), Gaps = 37/304 (12%)
Query: 2 MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEER----SKQLEDELAAMQK-------- 49
+E I +M+ +L++E DR +Q +AE+K+ ++ +QLE+E AA QK
Sbjct: 927 LEEILHEMEA-RLEEEE--DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 983
Query: 50 --KLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERL 107
K+K EDE+ + ++ +L E++ +D +A + + + + ++ + +
Sbjct: 984 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1043
Query: 108 ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVA 167
+ +L++ EK+ E E+ + +E A E++ + Q+ E K + +K EE+
Sbjct: 1044 SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK---MQLAKKEEELQ 1100
Query: 168 RKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIK 227
L ++ ++ + A K ELE + ++ +L S A K +++ EE++
Sbjct: 1101 AALARLDDEIAQKNN----ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 228 ILTDKLKEA--------ETRAEFAERSVAKLEKTIDD----LEDELYAQKLKYKAISEEL 275
L +L++ E RA+ E+ V L+K +D+ E ++ + K+ EEL
Sbjct: 1157 ALKTELEDTLDSTATQQELRAK-REQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1215
Query: 276 DHAL 279
L
Sbjct: 1216 TEQL 1219
Score = 64.3 bits (155), Expect = 1e-10
Identities = 54/256 (21%), Positives = 117/256 (45%), Gaps = 32/256 (12%)
Query: 6 KKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELA-------AMQKKLKGTEDEL 58
+KK + L+ D + AE +KQA+ ++L +ELA A+Q + + E +
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745
Query: 59 DKYSEALKDAQEKLELAEKKAADAEAEVASLNRRI----------QLVEEELDRAQERLA 108
+ E L++ Q +E + A + L+ + + ++L+R + L
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805
Query: 109 TALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVAR 168
+ L ++E A K+ +S + +E + + EE++E + + + A ++ D+K +E+
Sbjct: 1806 SKLHEMEGAVKSKFKST--IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEI-- 1861
Query: 169 KLVIIEGDLERTEERAELAES----------KCSELEEELKNVTNNLKSLEAQAEKYSQK 218
L+ +E + + E+ E AE + E EEE + + N + L+ + ++ ++
Sbjct: 1862 -LLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1920
Query: 219 EDKYEEEIKILTDKLK 234
+ E+ L KL+
Sbjct: 1921 NEAMGREVNALKSKLR 1936
Score = 62.4 bits (150), Expect = 4e-10
Identities = 61/285 (21%), Positives = 130/285 (45%), Gaps = 21/285 (7%)
Query: 7 KKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALK 66
KK++ L+ + + + A + +AE++ + L +EL A++ +L+ T D E L+
Sbjct: 1118 KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE-LR 1176
Query: 67 DAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESER 126
+E+ KKA D E S ++Q + ++ +A E L L++ + A+ D++++
Sbjct: 1177 AKREQEVTVLKKALDEETR--SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1234
Query: 127 GM-----------KVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEG 175
+ +V+ + E K + E Q++E + + +R E+ K+ ++
Sbjct: 1235 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 176 DLERTEERAELAESKCSELEEELKNVTNNLKSLEA-------QAEKYSQKEDKYEEEIKI 228
++E AE K +L +++ ++++ L+ + Q S K + EEE
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 229 LTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISE 273
L D+L E + ER ++ L + D + +L +A+ E
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399
Score = 62.4 bits (150), Expect = 4e-10
Identities = 65/298 (21%), Positives = 136/298 (45%), Gaps = 42/298 (14%)
Query: 7 KKMQMLKLDKENALDR-AEQAEAEQKQAEERS---KQLEDELAAMQKKLKGTEDELDKYS 62
++++ LK + E+ LD A Q E K+ +E + K L++E + + ++ ++ K++
Sbjct: 1153 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV---QEMRQKHA 1209
Query: 63 EALKDAQEKLE--------------LAEKKAADAEAEVASLNRRIQLVEEELDRAQERLA 108
+A+++ E+LE EK+ AD E+ L + Q VE + + + ++
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1269
Query: 109 TALQKLEEAEKAAD-------------ESERGM-KVIENRALKDEEKMELQEIQLKEAKH 154
K + E+A ES GM E +A+K + + QL++ +
Sbjct: 1270 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329
Query: 155 IAEEADRKYEEVARKLVIIEGD-------LERTEERAELAESKCSELEEELKNVTNNLKS 207
+ +E R+ V+ KL +E + L+ E + E S L +L + L+
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Query: 208 LEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQK 265
+ E + + ++++EI+ LT + +E + E++ +L++ +DDL +L Q+
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1447
Score = 58.9 bits (141), Expect = 5e-09
Identities = 66/334 (19%), Positives = 139/334 (41%), Gaps = 55/334 (16%)
Query: 3 EAIKKKMQMLKLDKENALDRAE-----------QAEAEQKQAEERSKQLEDELAAMQKKL 51
EA ++K+Q+ K+ E + + E + E+K EER L LA ++K
Sbjct: 970 EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA 1029
Query: 52 KGTEDELDKYSEALKDAQEKLELAEKK--------------AADAEAEVASLNRRIQLVE 97
K +K+ + + + +L+ EK A+D ++A L +I ++
Sbjct: 1030 KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1089
Query: 98 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE 157
+L + +E L AL +L++ + + + ++ +E +E ++ + + A++ AE
Sbjct: 1090 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE----RAARNKAE 1145
Query: 158 EADRKY-EEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYS 216
+ R EE+ +E L+ T + EL + E+ K + +S EAQ ++
Sbjct: 1146 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1205
Query: 217 QKEDKYEEEIKILTDKLKEAETR------------AEFA-------------ERSVAKLE 251
QK + EE+ ++ K A+ A+ A E KLE
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 252 KTIDDLEDELYAQKLKYKAISEELDHALNDMTSI 285
+ +L+ + + +++++ N++ S+
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHKLQNEVESV 1299
Score = 48.5 bits (114), Expect = 7e-06
Identities = 76/340 (22%), Positives = 135/340 (39%), Gaps = 81/340 (23%)
Query: 16 KENALDRAEQAEAEQKQAEERSKQLEDELAAMQ-----------------KKLKGTEDEL 58
K N + Q E E+ ++ QL++E+ A Q KKL+ +
Sbjct: 1338 KLNVSTKLRQLEEERNSLQD---QLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1394
Query: 59 DKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRA------QERLATALQ 112
+ E K Q+++E ++ + A L + +++ELD Q +L + L+
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1454
Query: 113 KLEE------------AEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 160
K + + K ADE +R E A + E K L+EA EE +
Sbjct: 1455 KKQRKFDQLLAEEKNISSKYADERDRA----EAEAREKETKALSLARALEEALEAKEELE 1510
Query: 161 R--------------KYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTN--- 203
R ++V + + +E E + E +++ ELE+EL+ +
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKL 1570
Query: 204 ----NLKSLEAQAEKYSQ-KEDKYEEEIKILTDKLKEAETRAE-------FAERSVAKLE 251
N+++L+ Q E+ Q ++++ EE+ + L +L E ET E A + KLE
Sbjct: 1571 RLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1630
Query: 252 KTIDDLE----------DELYAQKLKYKAISEELDHALND 281
+ DLE +E Q K +A ++ L D
Sbjct: 1631 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670
Score = 45.8 bits (107), Expect = 4e-05
Identities = 63/306 (20%), Positives = 130/306 (42%), Gaps = 39/306 (12%)
Query: 2 MEAIKKKMQMLKLDKENAL----DRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDE 57
+EA +++Q D E A D+ + + E + + E + + K + +
Sbjct: 1264 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1323
Query: 58 LDKYSEAL-KDAQEKLELAEK------------KAADAEAEV-ASLNRRIQLVEEELDRA 103
L E L ++ ++KL ++ K D E E +L R I + +L +
Sbjct: 1324 LQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS 1383
Query: 104 QERL---ATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 160
+++L A+ ++ LEE +K R K IEN + EEK + K + +E D
Sbjct: 1384 KKKLQDFASTVEALEEGKK------RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 161 RKYEEVARKLVIIEGDLERTEERAE--LAESK---------CSELEEELKNVTNNLKSLE 209
++ + ++ +LE+ + + + LAE K E E + SL
Sbjct: 1438 DLVVDLDNQRQLV-SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLA 1496
Query: 210 AQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYK 269
E+ + +++ E K+L ++++ + + ++V +LEK+ LE ++ K + +
Sbjct: 1497 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
Query: 270 AISEEL 275
+ +EL
Sbjct: 1557 ELEDEL 1562
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.120 0.289
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,469,114
Number of Sequences: 37866
Number of extensions: 396926
Number of successful extensions: 18677
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 882
Number of HSP's successfully gapped in prelim test: 1126
Number of HSP's that attempted gapping in prelim test: 3542
Number of HSP's gapped (non-prelim): 7564
length of query: 285
length of database: 18,247,518
effective HSP length: 101
effective length of query: 184
effective length of database: 14,423,052
effective search space: 2653841568
effective search space used: 2653841568
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.