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Search of human proteins with 22027618
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22027618 TNF receptor-associated factor 3 isoform 1 [Homo
sapiens]
(568 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22027616 TNF receptor-associated factor 3 isoform 1 [Homo sap... 1163 0.0
gi|22027618 TNF receptor-associated factor 3 isoform 1 [Homo sap... 1163 0.0
gi|22027620 TNF receptor-associated factor 3 isoform 2 [Homo sap... 1096 0.0
gi|22027627 TNF receptor-associated factor 5 [Homo sapiens] 457 e-128
gi|77404348 TNF receptor-associated factor 5 [Homo sapiens] 457 e-128
gi|11321603 TNF receptor-associated factor 5 [Homo sapiens] 457 e-128
gi|22027612 TNF receptor-associated factor 2 [Homo sapiens] 291 1e-78
gi|5032193 TNF receptor-associated factor 1 [Homo sapiens] 231 1e-60
gi|22027630 TNF receptor-associated factor 6 [Homo sapiens] 194 2e-49
gi|4759254 TNF receptor-associated factor 6 [Homo sapiens] 194 2e-49
gi|22027622 TNF receptor-associated factor 4 [Homo sapiens] 157 2e-38
gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens] 72 1e-12
gi|87241872 ring finger protein 151 [Homo sapiens] 71 3e-12
gi|45594312 TNF receptor-associated factor 7 [Homo sapiens] 64 3e-10
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 59 2e-08
gi|34577114 cytomatrix protein p110 [Homo sapiens] 54 3e-07
gi|37595555 ring finger protein 125 [Homo sapiens] 52 1e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 9e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 2e-05
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 48 3e-05
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 48 3e-05
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 47 5e-05
gi|30520320 ring finger protein 166 [Homo sapiens] 47 5e-05
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 46 8e-05
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 46 1e-04
gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens] 46 1e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 45 2e-04
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 45 2e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 44 3e-04
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 44 4e-04
>gi|22027616 TNF receptor-associated factor 3 isoform 1 [Homo
sapiens]
Length = 568
Score = 1163 bits (3008), Expect = 0.0
Identities = 568/568 (100%), Positives = 568/568 (100%)
Query: 1 MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60
MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL
Sbjct: 1 MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60
Query: 61 CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120
CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE
Sbjct: 61 CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120
Query: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180
SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC
Sbjct: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180
Query: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV 240
KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV
Sbjct: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV 240
Query: 241 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI 300
FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
Sbjct: 241 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI 300
Query: 301 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR 360
EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
Sbjct: 301 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR 360
Query: 361 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW 420
VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
Sbjct: 361 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW 420
Query: 421 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG 480
KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG
Sbjct: 421 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG 480
Query: 481 EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ 540
EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ
Sbjct: 481 EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ 540
Query: 541 TVLENGTYIKDDTIFIKVIVDTSDLPDP 568
TVLENGTYIKDDTIFIKVIVDTSDLPDP
Sbjct: 541 TVLENGTYIKDDTIFIKVIVDTSDLPDP 568
>gi|22027618 TNF receptor-associated factor 3 isoform 1 [Homo
sapiens]
Length = 568
Score = 1163 bits (3008), Expect = 0.0
Identities = 568/568 (100%), Positives = 568/568 (100%)
Query: 1 MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60
MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL
Sbjct: 1 MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60
Query: 61 CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120
CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE
Sbjct: 61 CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120
Query: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180
SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC
Sbjct: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180
Query: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV 240
KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV
Sbjct: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV 240
Query: 241 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI 300
FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
Sbjct: 241 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI 300
Query: 301 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR 360
EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
Sbjct: 301 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR 360
Query: 361 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW 420
VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
Sbjct: 361 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW 420
Query: 421 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG 480
KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG
Sbjct: 421 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG 480
Query: 481 EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ 540
EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ
Sbjct: 481 EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ 540
Query: 541 TVLENGTYIKDDTIFIKVIVDTSDLPDP 568
TVLENGTYIKDDTIFIKVIVDTSDLPDP
Sbjct: 541 TVLENGTYIKDDTIFIKVIVDTSDLPDP 568
>gi|22027620 TNF receptor-associated factor 3 isoform 2 [Homo
sapiens]
Length = 543
Score = 1096 bits (2834), Expect = 0.0
Identities = 543/568 (95%), Positives = 543/568 (95%), Gaps = 25/568 (4%)
Query: 1 MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60
MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL
Sbjct: 1 MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60
Query: 61 CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120
CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE
Sbjct: 61 CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120
Query: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180
SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC
Sbjct: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180
Query: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV 240
KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSE
Sbjct: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSE----------------------- 217
Query: 241 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI 300
GTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
Sbjct: 218 --GTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI 275
Query: 301 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR 360
EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
Sbjct: 276 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR 335
Query: 361 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW 420
VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
Sbjct: 336 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW 395
Query: 421 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG 480
KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG
Sbjct: 396 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG 455
Query: 481 EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ 540
EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ
Sbjct: 456 EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ 515
Query: 541 TVLENGTYIKDDTIFIKVIVDTSDLPDP 568
TVLENGTYIKDDTIFIKVIVDTSDLPDP
Sbjct: 516 TVLENGTYIKDDTIFIKVIVDTSDLPDP 543
>gi|22027627 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 457 bits (1175), Expect = e-128
Identities = 232/552 (42%), Positives = 354/552 (64%), Gaps = 21/552 (3%)
Query: 25 RSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSS 84
+++G + + + + +FV+ +E++YKC CH VL +P QT CGHRFC+ C+ +L +
Sbjct: 17 QNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELN 76
Query: 85 S-PKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHF 143
+ P C +E I +VFKDNCCKRE+L L +YC N + GC +++LG HL+ C F
Sbjct: 77 TVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSN-APGCNAKVILGRYQDHLQQ-CLF 134
Query: 144 EELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVS 203
+ + C C+E VLRKDL++H+ +C++R+ C +CK V +I LQ HE+ CP V
Sbjct: 135 QPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVF 194
Query: 204 CPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLL 263
CP+ C+ + +L++E+ HL+ C A C FK YGC + ++ HE S+ +H+ L+
Sbjct: 195 CPNNCA-KIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLV 253
Query: 264 KEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVI 323
E + LE+++S L +K IQ L I E E ++ ++ N S + ++Q V
Sbjct: 254 LEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQ-VF 312
Query: 324 DSQAEKLKELDKEIRPF------RQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARN 377
S +K L+ ++ +QN + + +V++++ ++T LE+ D+
Sbjct: 313 ASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQ-------R 365
Query: 378 TGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKT 437
+LE + ++HD +++H +L+ + RF++LE YNG LIWK+ DYK +K+EAV G T
Sbjct: 366 LAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHT 425
Query: 438 LSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLM 497
+S++SQ FYT GY++CAR YLNGDG G+G+HLSL+FV+MRGE+D+LL WPF+Q+VTLM
Sbjct: 426 VSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLM 485
Query: 498 LMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLEN--GTYIKDDTIF 555
L+DQ S ++++ + FKPDPNSSSFK+P GEMNIASGCP FVA +VLEN YIKDDT+F
Sbjct: 486 LLDQ-SGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLF 544
Query: 556 IKVIVDTSDLPD 567
+KV VD +DL D
Sbjct: 545 LKVAVDLTDLED 556
>gi|77404348 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 457 bits (1175), Expect = e-128
Identities = 232/552 (42%), Positives = 354/552 (64%), Gaps = 21/552 (3%)
Query: 25 RSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSS 84
+++G + + + + +FV+ +E++YKC CH VL +P QT CGHRFC+ C+ +L +
Sbjct: 17 QNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELN 76
Query: 85 S-PKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHF 143
+ P C +E I +VFKDNCCKRE+L L +YC N + GC +++LG HL+ C F
Sbjct: 77 TVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSN-APGCNAKVILGRYQDHLQQ-CLF 134
Query: 144 EELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVS 203
+ + C C+E VLRKDL++H+ +C++R+ C +CK V +I LQ HE+ CP V
Sbjct: 135 QPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVF 194
Query: 204 CPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLL 263
CP+ C+ + +L++E+ HL+ C A C FK YGC + ++ HE S+ +H+ L+
Sbjct: 195 CPNNCA-KIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLV 253
Query: 264 KEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVI 323
E + LE+++S L +K IQ L I E E ++ ++ N S + ++Q V
Sbjct: 254 LEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQ-VF 312
Query: 324 DSQAEKLKELDKEIRPF------RQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARN 377
S +K L+ ++ +QN + + +V++++ ++T LE+ D+
Sbjct: 313 ASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQ-------R 365
Query: 378 TGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKT 437
+LE + ++HD +++H +L+ + RF++LE YNG LIWK+ DYK +K+EAV G T
Sbjct: 366 LAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHT 425
Query: 438 LSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLM 497
+S++SQ FYT GY++CAR YLNGDG G+G+HLSL+FV+MRGE+D+LL WPF+Q+VTLM
Sbjct: 426 VSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLM 485
Query: 498 LMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLEN--GTYIKDDTIF 555
L+DQ S ++++ + FKPDPNSSSFK+P GEMNIASGCP FVA +VLEN YIKDDT+F
Sbjct: 486 LLDQ-SGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLF 544
Query: 556 IKVIVDTSDLPD 567
+KV VD +DL D
Sbjct: 545 LKVAVDLTDLED 556
>gi|11321603 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 457 bits (1175), Expect = e-128
Identities = 232/552 (42%), Positives = 354/552 (64%), Gaps = 21/552 (3%)
Query: 25 RSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSS 84
+++G + + + + +FV+ +E++YKC CH VL +P QT CGHRFC+ C+ +L +
Sbjct: 17 QNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELN 76
Query: 85 S-PKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHF 143
+ P C +E I +VFKDNCCKRE+L L +YC N + GC +++LG HL+ C F
Sbjct: 77 TVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSN-APGCNAKVILGRYQDHLQQ-CLF 134
Query: 144 EELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVS 203
+ + C C+E VLRKDL++H+ +C++R+ C +CK V +I LQ HE+ CP V
Sbjct: 135 QPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVF 194
Query: 204 CPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLL 263
CP+ C+ + +L++E+ HL+ C A C FK YGC + ++ HE S+ +H+ L+
Sbjct: 195 CPNNCA-KIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLV 253
Query: 264 KEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVI 323
E + LE+++S L +K IQ L I E E ++ ++ N S + ++Q V
Sbjct: 254 LEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQ-VF 312
Query: 324 DSQAEKLKELDKEIRPF------RQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARN 377
S +K L+ ++ +QN + + +V++++ ++T LE+ D+
Sbjct: 313 ASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQ-------R 365
Query: 378 TGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKT 437
+LE + ++HD +++H +L+ + RF++LE YNG LIWK+ DYK +K+EAV G T
Sbjct: 366 LAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHT 425
Query: 438 LSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLM 497
+S++SQ FYT GY++CAR YLNGDG G+G+HLSL+FV+MRGE+D+LL WPF+Q+VTLM
Sbjct: 426 VSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLM 485
Query: 498 LMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLEN--GTYIKDDTIF 555
L+DQ S ++++ + FKPDPNSSSFK+P GEMNIASGCP FVA +VLEN YIKDDT+F
Sbjct: 486 LLDQ-SGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLF 544
Query: 556 IKVIVDTSDLPD 567
+KV VD +DL D
Sbjct: 545 LKVAVDLTDLED 556
>gi|22027612 TNF receptor-associated factor 2 [Homo sapiens]
Length = 501
Score = 291 bits (744), Expect = 1e-78
Identities = 185/549 (33%), Positives = 286/549 (52%), Gaps = 82/549 (14%)
Query: 36 QGGYKEKFVKT-VEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTAC-QE 93
Q G+ + + T +E KY C C VL P Q +CGHR+C C+A++LSS C AC E
Sbjct: 16 QPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHE 75
Query: 94 SIVKDKV--------FKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEE 145
I ++ + F DN +RE+ +L C ++ GC + L CH
Sbjct: 76 GIYEEGISILESSSAFPDNAARREVESLPAVCPSD--GCTWKGTLKEY-----ESCHEGR 128
Query: 146 LPCVR---PDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVV 202
P + P CK V + H+E C R +C HC++ ++ H + CP +
Sbjct: 129 CPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEV-CPKFPL 187
Query: 203 SCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNL 262
+C C + + R + H+ C C F GC+ ++ + HE +H+ +
Sbjct: 188 TCDG-CGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAM 246
Query: 263 LKEWSNSLEKKVSLLQNESVEKNKSIQ---SLHNQICSFEIEIERQKEMLRNNESKILHL 319
L S+ LE K LL ++S ++ +Q SL + +FE ++
Sbjct: 247 LL--SSVLEAK-PLLGDQSHAGSELLQRCESLEKKTATFE------------------NI 285
Query: 320 QRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTE--LESVDKSAGQVARN 377
V++ + E++ +M + S Q+R+ + +E++ Q+ R+
Sbjct: 286 VCVLNREVERV------------------AMTAEACSRQHRLDQDKIEALSSKVQQLERS 327
Query: 378 TGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKT 437
GL D+ +AD++ + +E ++Y+GV IWKI D+ R++QEAV G+
Sbjct: 328 IGL--------------KDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRI 373
Query: 438 LSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLM 497
+++S FYT +GYKMC R+YLNGDG G+GTHLSLFFV+M+G DALL WPF QKVTLM
Sbjct: 374 PAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLM 433
Query: 498 LMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFI 556
L+DQ ++R H+ DAF+PD SSSF++P +MNIASGCP+F + +E +Y++DD IFI
Sbjct: 434 LLDQ-NNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFI 492
Query: 557 KVIVDTSDL 565
K IVD + L
Sbjct: 493 KAIVDLTGL 501
>gi|5032193 TNF receptor-associated factor 1 [Homo sapiens]
Length = 416
Score = 231 bits (589), Expect = 1e-60
Identities = 150/414 (36%), Positives = 219/414 (52%), Gaps = 55/414 (13%)
Query: 173 REATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTC 232
R C+ C S+ P + ED CP S + LR++ AH E A C
Sbjct: 34 RALCCAGCLSENP----RNGEDQICPKCRGEDLQSISPGSRLRTQEKAH-PEVAEAGIGC 88
Query: 233 SFKRYGCVFQGTNQQIKAHEASSAVQHVNLL----KEWSNSL-----EKKVSLLQNESVE 283
F GC F+G+ Q ++ HE +S H+NLL K+W L ++L QN S
Sbjct: 89 PFAGVGCSFKGSPQSVQEHEVTSQTSHLNLLLGFMKQWKARLGCGLESGPMALEQNLS-- 146
Query: 284 KNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN 343
+ +Q+ E++ R E + H + + L EL+ ++R F
Sbjct: 147 -DLQLQAAVEVAGDLEVDCYRAPCSESQEELALQHFMK-----EKLLAELEGKLRVFE-- 198
Query: 344 WEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRH------------DQM 391
++ ++ N+ E A +A T + +SQL R Q
Sbjct: 199 ---------NIVAVLNKEVE-------ASHLALATSIHQSQLDRERILSLEQRVVELQQT 242
Query: 392 LSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFG 451
L+ D L ++ +++E AS++G +WKI + RR E+ G+T+SL+S FYT +G
Sbjct: 243 LAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAKYG 302
Query: 452 YKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDA 511
YK+C R+YLNGDG GK THLSLF VIMRGEYDALLPWPF+ KVT ML+DQ ++R H DA
Sbjct: 303 YKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQ-NNREHAIDA 361
Query: 512 FKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLEN--GTYIKDDTIFIKVIVDTS 563
F+PD +S+SF++P E N+ASGCP+F + L++ Y+KDDT+F+K IV+TS
Sbjct: 362 FRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETS 415
>gi|22027630 TNF receptor-associated factor 6 [Homo sapiens]
Length = 522
Score = 194 bits (492), Expect = 2e-49
Identities = 142/536 (26%), Positives = 241/536 (44%), Gaps = 88/536 (16%)
Query: 32 FVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTAC 91
F+ E GY +F +E KY+C C + L QT CGHRFC++C+ + + KC
Sbjct: 49 FMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD 108
Query: 92 QESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRP 151
E ++++++F DN KREIL+L + C NE GC ++ L HL H + C F + C P
Sbjct: 109 NEILLENQLFPDNFAKREILSLMVKCPNE--GCLHKMELRHLEDH-QAHCEFALMDC--P 163
Query: 152 DCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQ 211
C+ + + H+ K C R+ +C +C + + + H D +CP V C + C+
Sbjct: 164 QCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIH-DQNCPLANVICEY-CNT- 220
Query: 212 TLLRSELSAHLS-ECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSL 270
L+R ++ H +C AP C+F +GC + + H + H+ +L + +SL
Sbjct: 221 ILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSL 280
Query: 271 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 330
SV + S ++ +F+ I + + L + +I L +++Q+ +
Sbjct: 281 ----------SVIPDSGYIS---EVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYV 327
Query: 331 KELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQ 390
EL + IR +L+++V E+E+
Sbjct: 328 SELKRTIR-----------------TLEDKVAEIEA------------------------ 346
Query: 391 MLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYF 450
NG+ IWKI ++ + K + ++S FYTG
Sbjct: 347 ---------------------QQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKP 385
Query: 451 GYKMCARVYLN-GDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSS--RRH 507
GYK+C R++L ++SLF M+GEYD+ LPWPF+ + L ++DQ + R++
Sbjct: 386 GYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQN 445
Query: 508 LGDAFKPDPNSSSFKKPTGEMNIAS-GCPVFVAQTVLENGTYIKDDTIFIKVIVDT 562
+ P +F++PT N G F+ L T+IKDDT+ ++ V T
Sbjct: 446 HEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST 501
>gi|4759254 TNF receptor-associated factor 6 [Homo sapiens]
Length = 522
Score = 194 bits (492), Expect = 2e-49
Identities = 142/536 (26%), Positives = 241/536 (44%), Gaps = 88/536 (16%)
Query: 32 FVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTAC 91
F+ E GY +F +E KY+C C + L QT CGHRFC++C+ + + KC
Sbjct: 49 FMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD 108
Query: 92 QESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRP 151
E ++++++F DN KREIL+L + C NE GC ++ L HL H + C F + C P
Sbjct: 109 NEILLENQLFPDNFAKREILSLMVKCPNE--GCLHKMELRHLEDH-QAHCEFALMDC--P 163
Query: 152 DCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQ 211
C+ + + H+ K C R+ +C +C + + + H D +CP V C + C+
Sbjct: 164 QCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIH-DQNCPLANVICEY-CNT- 220
Query: 212 TLLRSELSAHLS-ECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSL 270
L+R ++ H +C AP C+F +GC + + H + H+ +L + +SL
Sbjct: 221 ILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSL 280
Query: 271 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 330
SV + S ++ +F+ I + + L + +I L +++Q+ +
Sbjct: 281 ----------SVIPDSGYIS---EVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYV 327
Query: 331 KELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQ 390
EL + IR +L+++V E+E+
Sbjct: 328 SELKRTIR-----------------TLEDKVAEIEA------------------------ 346
Query: 391 MLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYF 450
NG+ IWKI ++ + K + ++S FYTG
Sbjct: 347 ---------------------QQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKP 385
Query: 451 GYKMCARVYLN-GDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSS--RRH 507
GYK+C R++L ++SLF M+GEYD+ LPWPF+ + L ++DQ + R++
Sbjct: 386 GYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQN 445
Query: 508 LGDAFKPDPNSSSFKKPTGEMNIAS-GCPVFVAQTVLENGTYIKDDTIFIKVIVDT 562
+ P +F++PT N G F+ L T+IKDDT+ ++ V T
Sbjct: 446 HEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST 501
>gi|22027622 TNF receptor-associated factor 4 [Homo sapiens]
Length = 470
Score = 157 bits (398), Expect = 2e-38
Identities = 140/544 (25%), Positives = 235/544 (43%), Gaps = 103/544 (18%)
Query: 38 GYKEKFVKTVEDKYKCEKCHLVLCSPKQTE-CGHRFCESCMAALLSSSSPKCTACQESIV 96
G+ KF++ + + C C + P Q CGHRFC++C+ LS KC Q +
Sbjct: 3 GFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLD 62
Query: 97 KDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEK 156
K++ D + ++L L I C
Sbjct: 63 YAKIYPDPELEVQVLGLPIRCI-------------------------------------- 84
Query: 157 VLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRS 216
H E+ C++ P+ LQ H +T C V+ CP++C ++ L R
Sbjct: 85 --------HSEEGCRWSG----------PLRHLQGHLNT-CSFNVIPCPNRCPMK-LSRR 124
Query: 217 ELSAHLS-ECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVS 275
+L AHL +C C F GC F G + ++HE + V + + +++
Sbjct: 125 DLPAHLQHDCPKRRLKCEF--CGCDFSG--EAYESHEGMCPQESVYCENKCGARMMRRL- 179
Query: 276 LLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDK 335
L Q+ + E K Q C+ E + +++++ + L +Q + + +
Sbjct: 180 LAQHATSECPKRTQPC--TYCTKEFVFDT----IQSHQYQCPRLPVACPNQCG-VGTVAR 232
Query: 336 EIRPFRQNWEEADSMKSSV-------ESLQNRVTELESVDKSAGQVARNTGLLESQLSRH 388
E P DS +++ ++R +L V + ++ + +SR
Sbjct: 233 EDLPGHLK----DSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQ 288
Query: 389 DQMLSVHDIRLADMDLRFQVLE-TASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYT 447
Q L +LR ++ E + +GVLIWKI Y RR QEA L +S FYT
Sbjct: 289 RQELQ---------ELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYT 339
Query: 448 GYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQG----S 503
+GYK+ +LNG+G G+GTHLSL+ ++ G +D LL WPF ++VT L+DQ +
Sbjct: 340 HKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLA 399
Query: 504 SRRHLGDAFKPDPNSSSFKKP------TGEMNIASGCPVFVAQTVLENGTYIKDDTIFIK 557
+H+ + F PDPN +F+KP E ++ G P F++ + Y++DD +FI+
Sbjct: 400 KPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIR 459
Query: 558 VIVD 561
V+
Sbjct: 460 AAVE 463
>gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens]
Length = 1066
Score = 72.0 bits (175), Expect = 1e-12
Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 1/133 (0%)
Query: 41 EKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKV 100
++F V+ KC CH VL P T CGH FC C+ + C+ + ++
Sbjct: 6 DRFDGDVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRLSAKEL 65
Query: 101 FKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRK 160
KR IL L I C +RGC + L L HL+ C F C C + +LR+
Sbjct: 66 NHVLPLKRLILKLDIKCAYATRGCGRVVKLQQLPEHLER-CDFAPARCRHAGCGQVLLRR 124
Query: 161 DLRDHVEKACKYR 173
D+ H+ AC R
Sbjct: 125 DVEAHMRDACDAR 137
>gi|87241872 ring finger protein 151 [Homo sapiens]
Length = 245
Score = 70.9 bits (172), Expect = 3e-12
Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 3/142 (2%)
Query: 37 GGYK-EKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESI 95
GGY F + + C CH VL P + C H FC+ C+ L+ C C++ +
Sbjct: 3 GGYDLNLFASPPDSNFVCSVCHGVLKRPARLPCSHIFCKKCILRWLARQK-TCPCCRKEV 61
Query: 96 VKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKE 155
+ KV N ++ I L++ C+N GC L H H ++ C FE C C
Sbjct: 62 KRKKVVHMNKLRKTIGRLEVKCKNADAGCIVTCPLAHRKGH-QDSCPFELTACPNEGCTS 120
Query: 156 KVLRKDLRDHVEKACKYREATC 177
+V R L +H + + + C
Sbjct: 121 QVPRGTLAEHRQHCQQGSQQRC 142
>gi|45594312 TNF receptor-associated factor 7 [Homo sapiens]
Length = 670
Score = 64.3 bits (155), Expect = 3e-10
Identities = 72/307 (23%), Positives = 109/307 (35%), Gaps = 65/307 (21%)
Query: 21 LHTDRSAG--TPVFVPEQGGYKEKFVKTVEDKYK--CEKCHLVLCSPKQTECGHRFCESC 76
LH++ S + +PE+ E V + K C+ C V P T CGH FC C
Sbjct: 95 LHSESSMSLRSTFSLPEEEEEPEPLVFAEQPSVKLCCQLCCSVFKDPVITTCGHTFCRRC 154
Query: 77 MAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVH 136
K C VK V +N E +G L +H
Sbjct: 155 AL--------KSEKCPVDNVKLTVVVNNIAVAE-------------------QIGELFIH 187
Query: 137 LKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTD 196
++ C V K + D R C + + A + HE +
Sbjct: 188 CRHGCR------VAGSGKPPIFEVDPRG---------------CPFTIKLSARKDHEGS- 225
Query: 197 CPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSA 256
C V CP+ S LLR L AHL EC + C +YGC F G + H +
Sbjct: 226 CDYRPVRCPNNPSCPPLLRMNLEAHLKECEHI--KCPHSKYGCTFIGNQDTYETHLETCR 283
Query: 257 VQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQ-------SLHNQICSFEIEIERQKEML 309
+ LKE+ + + + +K++ I L +I E +E + ++L
Sbjct: 284 FEG---LKEFLQQTDDRFHEMHVALAQKDQEIAFLRSMLGKLSEKIDQLEKSLELKFDVL 340
Query: 310 RNNESKI 316
N+SK+
Sbjct: 341 DENQSKL 347
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 58.5 bits (140), Expect = 2e-08
Identities = 49/207 (23%), Positives = 97/207 (46%), Gaps = 32/207 (15%)
Query: 263 LKEWSNSLEKKVSLLQNESVEKNKSIQSLHN-------QICSFEIEIERQKEMLRNNESK 315
L+ + +L++++S L N+ E K++ + + ++ +E + L NESK
Sbjct: 1510 LRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESK 1569
Query: 316 ILHLQ-RVIDSQAE---KLKELDKEIRPFRQNWE-EADSMKSSVES-------------- 356
ILH Q +++++AE KL E D+EI FR+ + DS++SS++S
Sbjct: 1570 ILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKK 1629
Query: 357 ----LQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETA 412
L +L ++ + ++ G L+ Q+ D + + D + DL+ QV
Sbjct: 1630 MEEDLNEMELQLSCANRQVSEATKSLGQLQIQIK--DLQMQLDDSTQLNSDLKEQVAVAE 1687
Query: 413 SYNGVLIWKIRDYKRRKQEAVMGKTLS 439
N +L ++ D + +++ G+ LS
Sbjct: 1688 RRNSLLQSELEDLRSLQEQTERGRRLS 1714
Score = 41.2 bits (95), Expect = 0.003
Identities = 33/144 (22%), Positives = 64/144 (44%), Gaps = 21/144 (14%)
Query: 246 QQIKAHEASSAVQHVNLLKEWSNSL-------EKKVSLLQNESVEKNKSIQSLHNQICSF 298
+++ E A + +NL + SL E V+ +Q E+ E + Q+ +
Sbjct: 1711 RRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKA 1770
Query: 299 EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSM-----KSS 353
IE E L+ + I HL+R ++ + + +L K + EA+ M +
Sbjct: 1771 AIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRL-------AEAEQMALMGSRKQ 1823
Query: 354 VESLQNRVTELESVDKSAGQVARN 377
++ L++RV ELE + G++ R+
Sbjct: 1824 IQKLESRVRELEG--ELEGEIRRS 1845
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 54.3 bits (129), Expect = 3e-07
Identities = 45/181 (24%), Positives = 84/181 (46%), Gaps = 22/181 (12%)
Query: 244 TNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESV--------------EKNKSIQ 289
T + +++ S QH+ +LKE + E++ ++LQ E +K K +Q
Sbjct: 455 TKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQ 514
Query: 290 SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADS 349
L + + EI K+ML E KI LQ+ I++ E+L++ DK++ + D
Sbjct: 515 DLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLK------DR 568
Query: 350 MKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHD--QMLSVHDIRLADMDLRFQ 407
+KS N T L +++++ + R L+ Q R D ++ + R + DL+ +
Sbjct: 569 VKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEK 628
Query: 408 V 408
V
Sbjct: 629 V 629
Score = 32.7 bits (73), Expect = 0.92
Identities = 30/155 (19%), Positives = 67/155 (43%), Gaps = 14/155 (9%)
Query: 257 VQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKI 316
++ + ++ + L++KV+ LQ E EK S+ L S ++ +SK+
Sbjct: 612 LEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKR-------DSKL 664
Query: 317 LHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVAR 376
L+ I+ + E+ +L+ +++ N E+ M +++ +DK A
Sbjct: 665 KSLEIAIEQKKEECSKLEAQLKK-AHNIEDDSRMNPEFAD------QIKQLDKEASYYRD 717
Query: 377 NTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLET 411
G ++++ R ++L + D D + LE+
Sbjct: 718 ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELES 752
>gi|37595555 ring finger protein 125 [Homo sapiens]
Length = 232
Score = 52.0 bits (123), Expect = 1e-06
Identities = 43/179 (24%), Positives = 69/179 (38%), Gaps = 27/179 (15%)
Query: 21 LHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAAL 80
L TD P + + + + + C C VL P +T CGH FC SC+A
Sbjct: 5 LSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSCIATS 64
Query: 81 LSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAE---QLMLGHLLVHL 137
L ++ C C+ + + V + KR ++E + CAE + L + H+
Sbjct: 65 LKNNKWTCPYCRAYLPSEGVPATDVAKR--------MKSEYKNCAECDTLVCLSEMRAHI 116
Query: 138 KNDCH--------FEELP-----CVRPDCKEKVLRKDLRDH--VEKACKYREATCSHCK 181
+ C +EL CV P C+ ++ L DH + R C C+
Sbjct: 117 RT-CQKYIDKYGPLQELEETAARCVCPFCQRELYEDSLLDHCITHHRSERRPVFCPLCR 174
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 49.3 bits (116), Expect = 9e-06
Identities = 31/169 (18%), Positives = 80/169 (47%), Gaps = 4/169 (2%)
Query: 267 SNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQ 326
+N+L++++ + E E+ K I+ ++ E + Q+ +R E K+ ++ + Q
Sbjct: 267 TNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQ 326
Query: 327 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLS 386
++L+E +KE+R ++ E+ + M+ E + + ++ ++ + E Q+
Sbjct: 327 EKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 386
Query: 387 RHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW----KIRDYKRRKQE 431
+Q + + R+ + D R + E +W K+R+ K+ +++
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQ 435
Score = 32.3 bits (72), Expect = 1.2
Identities = 22/105 (20%), Positives = 52/105 (49%), Gaps = 6/105 (5%)
Query: 264 KEWSNS--LEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQR 321
K W +EKK + ++ ++ + ++ ++ E ++ ++EM+R E K+ +
Sbjct: 559 KMWDQEERMEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 322 VIDSQAEKLKELDKEIRPFRQN-WEEADSMKSSVESL--QNRVTE 363
+ Q EK+ E +++++ + WE+ + M E + Q R+ E
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662
Score = 32.0 bits (71), Expect = 1.6
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
Query: 271 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 330
E+K L ++E +++ + I ++ E ++ Q+E +R E K+ + + Q EK+
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 331 -KELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQ 373
+ +K + W + + M+ ++ + ++ E E +K GQ
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQE--EKMRGQ 873
Score = 30.8 bits (68), Expect = 3.5
Identities = 28/164 (17%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 246 QQIKAHEASSAVQHVNLLKEWSNSLEKKV----SLLQNESV-EKNKSIQSLHNQICSFEI 300
+Q K E + +++ + EKK + + ES+ E+ K ++ + E
Sbjct: 675 EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEE 734
Query: 301 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDK------------EIRPFRQNWEEAD 348
+++ Q+E ++ E ++ + + Q EK+ E + +++ + WE+ +
Sbjct: 735 KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEE 794
Query: 349 SMKSSVESLQNRVTELE-SVDKSAGQVARNTGLLESQLSRHDQM 391
M+ E ++ + ++ +K GQ + G E + ++M
Sbjct: 795 KMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKM 838
Score = 30.0 bits (66), Expect = 5.9
Identities = 21/109 (19%), Positives = 49/109 (44%), Gaps = 1/109 (0%)
Query: 271 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 330
EKK+ + E+ + +Q ++ E ++ Q+E ++ E K+ + + Q EK+
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Query: 331 KELDKEIRPFRQNWE-EADSMKSSVESLQNRVTELESVDKSAGQVARNT 378
E + + WE E + ++ + ++ E E ++K + + T
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Score = 29.6 bits (65), Expect = 7.8
Identities = 28/163 (17%), Positives = 68/163 (41%), Gaps = 23/163 (14%)
Query: 246 QQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQ 305
Q+ K + +Q ++E + ++ ++ + + K +++ Q E E Q
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE-----EKEWQ 489
Query: 306 KEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNW-------------EEADSMKS 352
++ L + K+ Q + Q EK+ E +++IR + W E+ D M
Sbjct: 490 QQRLPEQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 548
Query: 353 SVESLQNRVTEL----ESVDKSAGQVARNTGLLESQLSRHDQM 391
E ++++ ++ E ++K + + T E ++ ++M
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM 591
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/167 (17%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Query: 267 SNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQ 326
+N+L++++ + E E+ K I+ ++ E + Q+ +R E K+ ++ + Q
Sbjct: 229 TNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQ 288
Query: 327 AEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLS 386
++L+E +KE+R ++ E+ + M+ E + + ++ ++ + E Q+
Sbjct: 289 EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 348
Query: 387 RHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAV 433
+Q + + R+ + D R + E +W+ ++ K +++E +
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWE-QEEKMQEEERI 394
Score = 33.5 bits (75), Expect = 0.54
Identities = 33/176 (18%), Positives = 78/176 (44%), Gaps = 12/176 (6%)
Query: 263 LKEWSNSLEKKVSLLQNESV-EKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQR 321
++E E++ + + E + E+ K ++ + E ++++Q+E + E K QR
Sbjct: 375 MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434
Query: 322 VIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVE--SLQNRVTELESVDKSAGQVARNTG 379
+ Q EKL E +K + WE+ + ++ E + ++ E + + Q+
Sbjct: 435 -LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ-- 491
Query: 380 LLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW----KIRDYKRRKQE 431
E ++ +Q + + R+ + D R + E +W K+R+ K+ +++
Sbjct: 492 --EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
Score = 32.7 bits (73), Expect = 0.92
Identities = 20/145 (13%), Positives = 67/145 (46%), Gaps = 8/145 (5%)
Query: 299 EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQ 358
E ++ Q+E +R+ E K+ + + Q E+L+E ++ +R ++ W++ + M+ ++ +
Sbjct: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQE 544
Query: 359 NRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVL 418
+ +K + E ++ ++M+ + ++ + + + + E
Sbjct: 545 QEKKTWDQEEKMREEERMRE--REKKMREEEEMMREQEEKMQEQEEKMREQEEK------ 596
Query: 419 IWKIRDYKRRKQEAVMGKTLSLYSQ 443
+W+ + + ++E + + ++ Q
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQ 621
Score = 32.7 bits (73), Expect = 0.92
Identities = 19/125 (15%), Positives = 56/125 (44%), Gaps = 4/125 (3%)
Query: 283 EKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQ 342
E+ K ++ + E +++ Q+E +R E K+ + + Q EK+ E ++++
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM----W 619
Query: 343 NWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADM 402
EE D M+ E + + +++ ++ + E ++ ++ + + ++ +
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Query: 403 DLRFQ 407
+ + Q
Sbjct: 680 EEKMQ 684
Score = 32.3 bits (72), Expect = 1.2
Identities = 24/138 (17%), Positives = 57/138 (41%), Gaps = 12/138 (8%)
Query: 264 KEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVI 323
K W E K+ + E+ + +Q ++ E ++ Q+E +R E K+ + +
Sbjct: 617 KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 676
Query: 324 DSQAEKLKELDKEIRPFRQN--------WEEADSMKSSVESLQNRVTELESVDKSAGQVA 375
Q EK++ ++++R + W + + M E + + E ++ Q
Sbjct: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE 736
Query: 376 RNTGLLESQLSRHDQMLS 393
+ ++ +L H++ S
Sbjct: 737 K----MQERLPEHEERCS 750
Score = 31.6 bits (70), Expect = 2.0
Identities = 24/136 (17%), Positives = 60/136 (44%), Gaps = 2/136 (1%)
Query: 271 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 330
E K+ + + + K ++ ++ E E+ QK+ LR E ++ + + Q EK+
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK-LREQEEQMQEQEEKMWEQEEKM 326
Query: 331 KELDKEI-RPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHD 389
+E ++++ R + WE+ M+ + ++++ + D+ + E + +
Sbjct: 327 REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEE 386
Query: 390 QMLSVHDIRLADMDLR 405
+M IR + +R
Sbjct: 387 KMQEEERIREREKKMR 402
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 47.8 bits (112), Expect = 3e-05
Identities = 41/165 (24%), Positives = 78/165 (47%), Gaps = 28/165 (16%)
Query: 244 TNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESV--------------EKNKSIQ 289
T + ++ S + QH+ +LKE + E++ ++LQ E +K K IQ
Sbjct: 487 TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ 546
Query: 290 SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADS 349
+ + + EI K+ML E K+ LQ+ I++ E+L++ +K++ S
Sbjct: 547 DMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQM----------SS 596
Query: 350 MKSSVESLQ----NRVTELESVDKSAGQVARNTGLLESQLSRHDQ 390
+K V+SLQ N T L +++++ + R L+ Q R ++
Sbjct: 597 LKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER 641
Score = 34.7 bits (78), Expect = 0.24
Identities = 50/269 (18%), Positives = 120/269 (44%), Gaps = 30/269 (11%)
Query: 152 DCKEKV--LRKDLRDHVEKACKYREATCSHCKSQVPM--------IALQKHEDTDCPCVV 201
D KEKV L+ DL + +E S S + IAL++ ++ C+
Sbjct: 656 DLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEE---CLK 712
Query: 202 VSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVN 261
+ K + + L + S +S+ + +R ++ + + +A E ++ +
Sbjct: 713 MESQLKKAHEAALEARASPEMSDRIQ-----HLEREITRYKDESSKAQA-EVDRLLEILK 766
Query: 262 LLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLR-------NNES 314
++ N +KK++ L+ + ++NK + +L ++ ++E ++ +ML N
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHK---EQVEKKKSAQMLEEARRREDNLND 823
Query: 315 KILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQ-NRVTELESVDKSAGQ 373
LQ + + ++++EL++ +R Q E + + + ES + N ++E + + +
Sbjct: 824 SSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEK 883
Query: 374 VARNTGLLESQLSRHDQMLSVHDIRLADM 402
V + ++++LS Q L+ + L ++
Sbjct: 884 VKQELESMKAKLSSTQQSLAEKETHLTNL 912
Score = 33.9 bits (76), Expect = 0.41
Identities = 28/129 (21%), Positives = 62/129 (48%), Gaps = 23/129 (17%)
Query: 258 QHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSL--------------HNQICSFEIEIE 303
+ ++ K+ L++KVSLLQ + EK S+ L +++ + EI +E
Sbjct: 645 EEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALE 704
Query: 304 RQKEMLRNNESKILHLQ------RVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESL 357
++KE ES++ R +++++ L++EI ++ +E+ ++ V+ L
Sbjct: 705 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK---DESSKAQAEVDRL 761
Query: 358 QNRVTELES 366
+ E+E+
Sbjct: 762 LEILKEVEN 770
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 47.8 bits (112), Expect = 3e-05
Identities = 41/165 (24%), Positives = 78/165 (47%), Gaps = 28/165 (16%)
Query: 244 TNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESV--------------EKNKSIQ 289
T + ++ S + QH+ +LKE + E++ ++LQ E +K K IQ
Sbjct: 459 TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ 518
Query: 290 SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADS 349
+ + + EI K+ML E K+ LQ+ I++ E+L++ +K++ S
Sbjct: 519 DMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQM----------SS 568
Query: 350 MKSSVESLQ----NRVTELESVDKSAGQVARNTGLLESQLSRHDQ 390
+K V+SLQ N T L +++++ + R L+ Q R ++
Sbjct: 569 LKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER 613
Score = 34.7 bits (78), Expect = 0.24
Identities = 50/269 (18%), Positives = 120/269 (44%), Gaps = 30/269 (11%)
Query: 152 DCKEKV--LRKDLRDHVEKACKYREATCSHCKSQVPM--------IALQKHEDTDCPCVV 201
D KEKV L+ DL + +E S S + IAL++ ++ C+
Sbjct: 628 DLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEE---CLK 684
Query: 202 VSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVN 261
+ K + + L + S +S+ + +R ++ + + +A E ++ +
Sbjct: 685 MESQLKKAHEAALEARASPEMSDRIQ-----HLEREITRYKDESSKAQA-EVDRLLEILK 738
Query: 262 LLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLR-------NNES 314
++ N +KK++ L+ + ++NK + +L ++ ++E ++ +ML N
Sbjct: 739 EVENEKNDKDKKIAELERQVKDQNKKVANLKHK---EQVEKKKSAQMLEEARRREDNLND 795
Query: 315 KILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQ-NRVTELESVDKSAGQ 373
LQ + + ++++EL++ +R Q E + + + ES + N ++E + + +
Sbjct: 796 SSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEK 855
Query: 374 VARNTGLLESQLSRHDQMLSVHDIRLADM 402
V + ++++LS Q L+ + L ++
Sbjct: 856 VKQELESMKAKLSSTQQSLAEKETHLTNL 884
Score = 33.9 bits (76), Expect = 0.41
Identities = 28/129 (21%), Positives = 62/129 (48%), Gaps = 23/129 (17%)
Query: 258 QHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSL--------------HNQICSFEIEIE 303
+ ++ K+ L++KVSLLQ + EK S+ L +++ + EI +E
Sbjct: 617 EEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALE 676
Query: 304 RQKEMLRNNESKILHLQ------RVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESL 357
++KE ES++ R +++++ L++EI ++ +E+ ++ V+ L
Sbjct: 677 QKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYK---DESSKAQAEVDRL 733
Query: 358 QNRVTELES 366
+ E+E+
Sbjct: 734 LEILKEVEN 742
>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
sapiens]
Length = 773
Score = 47.0 bits (110), Expect = 5e-05
Identities = 47/196 (23%), Positives = 77/196 (39%), Gaps = 45/196 (22%)
Query: 51 YKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREI 110
++C C + P T CGH FC++C+ L +P C C+ES+ +E
Sbjct: 477 FECSLCMRLFFEPVTTPCGHSFCKNCLERCL-DHAPYCPLCKESL------------KEY 523
Query: 111 LALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKAC 170
LA + YC + E+L++ +L PD E RK + D
Sbjct: 524 LADRRYCVTQ---LLEELIVKYL-----------------PD--ELSERKKIYDE----- 556
Query: 171 KYREATCSHCKSQVPM-IALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAP 229
A SH VP+ + + CP V ++ ++ +++ + CV+
Sbjct: 557 --ETAELSHLTKNVPIFVCTMAYPTVPCPLHVFEPRYRLMIRRSIQTG-TKQFGMCVSDT 613
Query: 230 STCSFKRYGCVFQGTN 245
SF YGC+ Q N
Sbjct: 614 QN-SFADYGCMLQIRN 628
Score = 30.4 bits (67), Expect = 4.5
Identities = 12/44 (27%), Positives = 20/44 (45%), Gaps = 3/44 (6%)
Query: 52 KCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESI 95
+C C L P CGH +C C+ L + +C C++ +
Sbjct: 122 RCLGCRGFLSEPVTVPCGHSYCRRCLRRELRA---RCRLCRDRL 162
>gi|30520320 ring finger protein 166 [Homo sapiens]
Length = 237
Score = 47.0 bits (110), Expect = 5e-05
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 5/100 (5%)
Query: 47 VEDKYKCEKCHLVLCSPKQT-ECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNC 105
+E +Y C C V P CGH FC C+ L SP C C+ KV K
Sbjct: 27 LEAQYTCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKATH 86
Query: 106 CKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEE 145
++++ + + C RGC +++ L + VH+ + +E
Sbjct: 87 VEKQLSSYKAPC----RGCNKKVTLAKMRVHISSCLKVQE 122
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 46.2 bits (108), Expect = 8e-05
Identities = 36/161 (22%), Positives = 80/161 (49%), Gaps = 16/161 (9%)
Query: 252 EASSAVQHVNL-LKEWSNSLEKKVSLLQN-------ESVEKNKSIQSLHNQICSFEIEIE 303
+ ++ V H+++ ++E +E+K+ L+ E E NK I+SL++++ + + ++
Sbjct: 1141 QRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLR 1200
Query: 304 RQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQ----NWEEA----DSMKSSVE 355
++ ++ NE +I L++ I+ +++KE++ ++ Q ++EA ++ + E
Sbjct: 1201 EKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTRE 1260
Query: 356 SLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHD 396
+QN TEL Q R L S+L Q+ D
Sbjct: 1261 QVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKD 1301
Score = 41.2 bits (95), Expect = 0.003
Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 18/125 (14%)
Query: 246 QQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQ 305
Q+++ SSA E +E+K +E+ K + + L +IE+++
Sbjct: 944 QELQKQRESSA--------EKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQY 995
Query: 306 KEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE 365
KE L E +I+HL+R +++A L +LD + D K+ +E N V ELE
Sbjct: 996 KEELSKMEKEIMHLKRDGENKAMHLSQLDMIL----------DQTKTELEKKTNAVKELE 1045
Query: 366 SVDKS 370
+ S
Sbjct: 1046 KLQHS 1050
Score = 34.3 bits (77), Expect = 0.31
Identities = 39/172 (22%), Positives = 75/172 (43%), Gaps = 26/172 (15%)
Query: 242 QGTNQQIKAHEASSAVQ--------HVNLLK----EWSNSLEKK---VSLLQNESVEKNK 286
Q + + IK + SA++ H+N L+ ++ L+KK V LQ E KN
Sbjct: 836 QVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNH 895
Query: 287 SIQSLHNQICSFEIEIERQKEMLRN---NESKILHLQRVIDSQAEKL-----KELDKEIR 338
S+Q Q + +++Q++ML+ ++ Q ++ Q KL K+ +
Sbjct: 896 SLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAE 955
Query: 339 PFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQ 390
R+ E+ +S + + +V EL +A QV + +LS+ ++
Sbjct: 956 KLRKMEEKCESAAHEADLKRQKVIELTG---TARQVKIEMDQYKEELSKMEK 1004
Score = 33.1 bits (74), Expect = 0.70
Identities = 42/206 (20%), Positives = 81/206 (39%), Gaps = 48/206 (23%)
Query: 258 QHVNLLKEWSNSLEK----------------------------KVSLLQNESVEKNKSIQ 289
Q + L+E N L + KVS+L++ + ++ S+
Sbjct: 229 QEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLES-AQQQAASVP 287
Query: 290 SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEI------------ 337
L QI + E E+ Q ++LR E+K+ Q+++ + + L+E +E
Sbjct: 288 ILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTK 347
Query: 338 ---RPFRQNWE---EADSMKSSVESLQNRVTE-LESVDKSAGQVARNTGLLESQLSRHDQ 390
R RQ E A+ + + + + +V E LE V + RN E + R +
Sbjct: 348 QGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQE 407
Query: 391 MLSVHDIRLADMDLRFQVLETASYNG 416
++ L + + + L+ + NG
Sbjct: 408 RCGLYKSELEILKEKLRQLKEENNNG 433
Score = 29.6 bits (65), Expect = 7.8
Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 7/84 (8%)
Query: 263 LKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRN-----NESKIL 317
LKE +N+ ++K+ ++ ++ E + I E E+E + E+LR+ NE++ L
Sbjct: 426 LKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENREL 485
Query: 318 HLQRVIDSQAEKLKELDKEIRPFR 341
++ + +Q E+L +EI R
Sbjct: 486 KVR--VAAQNERLDLCQQEIESSR 507
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 45.8 bits (107), Expect = 1e-04
Identities = 50/212 (23%), Positives = 92/212 (43%), Gaps = 12/212 (5%)
Query: 211 QTLLRSELSAHLSECVNAPSTCSFKRYGCVFQGTNQQIKAH--EASSAVQHVNLLKEWSN 268
Q L E + EC N CS + V Q K S++V+ V L++ +
Sbjct: 336 QEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALS 395
Query: 269 SLEKKV----SLLQNESVEKNKSIQSLHNQICSFEIEI-ERQKEMLRNNESKILHLQRVI 323
E ++ SL Q+ S+ ++ + ++ E + ++KE L+ + K+ + VI
Sbjct: 396 DAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVI 455
Query: 324 DSQAEKLKELDKEIRPFRQNWE-EADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLE 382
S A + LD E+ R N E + + S+ + + E+E +D+ + ++ L++
Sbjct: 456 KSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIK 515
Query: 383 SQLSRH----DQMLSVHDIRLADMDLRFQVLE 410
QLS+ D ++S L D R LE
Sbjct: 516 DQLSKQQNEGDSIISKLKQDLNDEKKRVHQLE 547
Score = 35.0 bits (79), Expect = 0.18
Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 6/115 (5%)
Query: 246 QQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQ---NESVEKNKSIQSLHNQICSFEIEI 302
Q+ K ++ A+ ++L K+ LE KV L N+S E N SIQ + ++ +
Sbjct: 560 QKEKLIQSEVALNDLHLTKQ---KLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQN 616
Query: 303 ERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESL 357
E + +RN + L+ + + LKE + E+R +QN E + + +++ +
Sbjct: 617 EEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKV 671
Score = 34.7 bits (78), Expect = 0.24
Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 10/130 (7%)
Query: 262 LLKEWSNSLEKKVSLLQNESVEKNKSIQSL----HNQICSFEIEIERQKEMLRNNESKIL 317
+L E S L++++ L+ EK+ +I++L H S E +++ +S+I
Sbjct: 1337 VLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIK 1396
Query: 318 HLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARN 377
L+ D + LKE D I+ ++D + SS E+ N+V E E + ++ +
Sbjct: 1397 QLKEKQDVLQKLLKEKDLLIKA------KSDQLLSSNENFTNKVNENELLRQAVTNLKER 1450
Query: 378 TGLLESQLSR 387
+LE + +
Sbjct: 1451 ILILEMDIGK 1460
Score = 33.5 bits (75), Expect = 0.54
Identities = 36/178 (20%), Positives = 79/178 (44%), Gaps = 16/178 (8%)
Query: 252 EASSAVQHVNLLKEWSNSLEKKV----SLLQNESVEKNKSIQSLHNQICSFE-------I 300
EA +A L++ LE+K+ + ++N S + + ++SL Q+ +
Sbjct: 1598 EALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETAL 1657
Query: 301 EIERQKEMLRNNESKILHLQRVID--SQAEKLK---ELDKEIRPFRQNWEEADSMKSSVE 355
++ +E ++ + +LQ V++ Q EK EL+K+ + + + A++++ V
Sbjct: 1658 QLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVI 1717
Query: 356 SLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETAS 413
SLQ + E + SA ++ + E Q+ + + L D+ + L +S
Sbjct: 1718 SLQECLDEANAALDSASRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMSLANSS 1775
Score = 33.1 bits (74), Expect = 0.70
Identities = 30/177 (16%), Positives = 77/177 (43%), Gaps = 7/177 (3%)
Query: 260 VNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHL 319
++ LK+ N +K+V L+++ ++ K + ++ E+ + + E K+ +L
Sbjct: 529 ISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENL 588
Query: 320 QRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTEL-ESVDKSAGQVARNT 378
++ E + KE N E + ++ + E L EL +S+++ + ++T
Sbjct: 589 VDQLNKSQESNVSIQKE------NLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDT 642
Query: 379 GLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMG 435
L E + + ++ ++ + +L+ + N L+ D + + +E + G
Sbjct: 643 LLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAG 699
Score = 31.2 bits (69), Expect = 2.7
Identities = 47/237 (19%), Positives = 95/237 (40%), Gaps = 59/237 (24%)
Query: 252 EASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEI---ERQKEM 308
+ S V +L K + ++K + +LQ E VE K ++ L ++I ++ E +++
Sbjct: 274 QGGSGVIETDLSKIYE--MQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDI 331
Query: 309 LRNNESKILHLQRVIDSQAEKLKELDKEIRPFR-----------------QNWEEADSMK 351
LR + ++ +R I + E LK +++P + EE ++
Sbjct: 332 LRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQ 391
Query: 352 SSVESLQNRVTELESVDKSAGQVARNTGLL---------ESQLSRHDQMLSV-------- 394
++ +N + L S+++ N L +S LS+ + L +
Sbjct: 392 QALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNE 451
Query: 395 ------------------HDIRLADMDLRFQVL-ETASYNGVLIWKIRDYKRRKQEA 432
HD+RL +++ + Q L ++ S LI +I + R+ QEA
Sbjct: 452 YEVIKSTATRDISLDSELHDLRL-NLEAKEQELNQSISEKETLIAEIEELDRQNQEA 507
>gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens]
Length = 245
Score = 45.8 bits (107), Expect = 1e-04
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 8/96 (8%)
Query: 48 EDKYKCEKCHLVLCSP-KQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCC 106
ED + C C VL +P + T C H FC C + S C C+ ++ + ++ C
Sbjct: 13 EDDFYCPVCQEVLKTPVRTTACQHVFCRKCFLTAMRESGAHCPLCRGNVTR----RERAC 68
Query: 107 KREILALQIYCRNES---RGCAEQLMLGHLLVHLKN 139
L L+ R S R CA+Q+ + H K+
Sbjct: 69 PERALDLENIMRKFSGSCRCCAKQIKFYRMRHHYKS 104
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 44.7 bits (104), Expect = 2e-04
Identities = 24/123 (19%), Positives = 59/123 (47%), Gaps = 1/123 (0%)
Query: 271 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 330
E+K+ + + E+ + + ++C E +++ Q+E +R E KI ++ I Q EK+
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657
Query: 331 KELDKEIRPFRQN-WEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHD 389
+E ++ ++ + WE+ + M E +Q + ++ ++ + E ++ H
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717
Query: 390 QML 392
+ L
Sbjct: 718 EHL 720
Score = 39.3 bits (90), Expect = 0.010
Identities = 39/201 (19%), Positives = 84/201 (41%), Gaps = 22/201 (10%)
Query: 263 LKEWSNSLEKKVSLL-----QNESVEKNKSIQSLHNQICSFEIEIE-------RQKEMLR 310
+KE LE+ LL Q E+ K +QS+ ++ + E E +Q+E +
Sbjct: 305 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 364
Query: 311 NNESKILHLQRVIDSQAEKLKELDKEIRPFRQN--------WEEADSMKSSVESLQNRVT 362
E KI + I Q EK++E +++IR + WE+ + M+ E + +
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424
Query: 363 ELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKI 422
++ ++ + LE ++ +++ + R + +R Q E +W+
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKMWRQ 482
Query: 423 RDYKRRKQEAVMGKTLSLYSQ 443
+ R ++E + + ++ Q
Sbjct: 483 EEKIREQEEKIREQEEKMWRQ 503
Score = 36.6 bits (83), Expect = 0.063
Identities = 27/168 (16%), Positives = 73/168 (43%), Gaps = 9/168 (5%)
Query: 245 NQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESV-EKNKSIQSLHNQICSFEIEIE 303
++Q K E + + ++ E++ Q E + E+ + I+ ++ E ++
Sbjct: 508 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567
Query: 304 RQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQ--------NWEEADSMKSSVE 355
Q+E +R E K+ + I Q EK++E +++IR + E+ + M E
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 356 SLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMD 403
+Q + ++ ++ + + E ++ ++M+ + ++ + +
Sbjct: 628 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
Score = 35.4 bits (80), Expect = 0.14
Identities = 26/117 (22%), Positives = 51/117 (43%), Gaps = 7/117 (5%)
Query: 246 QQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSI----QSLHNQ---ICSF 298
Q+ K + ++E E++ Q E + + + I + +H Q I
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555
Query: 299 EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVE 355
E ++ RQ+E + + E KI + + Q EK++E +++IR + E + M E
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQE 612
Score = 33.1 bits (74), Expect = 0.70
Identities = 34/197 (17%), Positives = 86/197 (43%), Gaps = 8/197 (4%)
Query: 243 GTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEI 302
G Q + + + V+ L + E+K+ + + E + IQ +I E +I
Sbjct: 332 GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 391
Query: 303 ERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQ-NWEEADSMKSSVESL--QN 359
Q+E +R E + + + Q E + E ++++R + WE+ + ++ E + Q
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 451
Query: 360 RVTELESVDKSAGQVARNTGL--LESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGV 417
++ E E + ++ E+++ R ++ + + ++ + + + E +
Sbjct: 452 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQE 511
Query: 418 LIWKIRDYKRRKQEAVM 434
KIR+ ++R+++ M
Sbjct: 512 ---KIREEEKRQEQEEM 525
>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
Length = 1194
Score = 44.7 bits (104), Expect = 2e-04
Identities = 36/147 (24%), Positives = 64/147 (43%), Gaps = 15/147 (10%)
Query: 249 KAHEASSAVQHVNLLKE---WSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQ 305
KA EA+S +Q LKE +E++++ L+ + + SLH+ E E+ +
Sbjct: 279 KAEEANSKLQRD--LKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASK 336
Query: 306 KEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE 365
+ + R +E K L +D +KL +Q ++A+++ L RV L
Sbjct: 337 ESLYRQSEEKSRQLAEWLDDAKQKL----------QQTLQKAETLPEIEAQLAQRVAALN 386
Query: 366 SVDKSAGQVARNTGLLESQLSRHDQML 392
++ G LE+QL +Q L
Sbjct: 387 KAEERHGNFEERLRQLEAQLEEKNQEL 413
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 44.3 bits (103), Expect = 3e-04
Identities = 33/149 (22%), Positives = 69/149 (46%), Gaps = 14/149 (9%)
Query: 269 SLEKKVSLLQNESVEKNKSIQSLHNQICSFE---IEIERQKEMLRNNESKILHLQRVIDS 325
+L +K LLQ EK +++ S C ++ I++E + ++S I HLQ
Sbjct: 1744 NLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQ----- 1798
Query: 326 QAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQL 385
E+L+E +K+ E + K+++++ QN + V K+ + +LE ++
Sbjct: 1799 --EELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKI 1856
Query: 386 SRHDQML----SVHDIRLADMDLRFQVLE 410
D L VH + + ++ +++ L+
Sbjct: 1857 KELDSCLVRQKEVHRVEMEELTSKYEKLQ 1885
Score = 42.7 bits (99), Expect = 9e-04
Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 35/168 (20%)
Query: 247 QIKAHEASSAVQHVNLLKEW------------------SNSLEKKVSLLQNESVEKNKSI 288
++K+ EA + +NLLKE + +EKK S L+ E + I
Sbjct: 1468 ELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARI 1527
Query: 289 QSLHNQICSFEIEIERQKEMLRNNE-----------SKILHLQRVIDSQAEKLKELDKEI 337
L + I IEIE E+L+N K+ H Q + + + ++KE +++I
Sbjct: 1528 MELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1587
Query: 338 RPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQL 385
+ SMK+ +E+ + ELE V+ S LE +L
Sbjct: 1588 LTLE---NQVYSMKAELET---KKKELEHVNLSVKSKEEELKALEDRL 1629
Score = 33.1 bits (74), Expect = 0.70
Identities = 47/195 (24%), Positives = 79/195 (40%), Gaps = 41/195 (21%)
Query: 249 KAHEASSAVQHVNLLKEWSNSLEKK----------VSLLQNESVEKNKSIQSLHNQI--- 295
K S QH N +KE LE K ++LL+ E ++NK L ++
Sbjct: 1446 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1505
Query: 296 --------CSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL-----------KELDKE 336
+ E E++ Q + E I I+S E L KEL ++
Sbjct: 1506 KSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQK 1565
Query: 337 IRPFRQNWEEADSMKSSVE----SLQNRV----TELESVDKSAGQVARNTGLLESQL-SR 387
++ F++ EE D+ E +L+N+V ELE+ K V + E +L +
Sbjct: 1566 LQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1625
Query: 388 HDQMLSVHDIRLADM 402
D++ S +LA++
Sbjct: 1626 EDRLESESAAKLAEL 1640
Score = 32.3 bits (72), Expect = 1.2
Identities = 41/176 (23%), Positives = 77/176 (43%), Gaps = 28/176 (15%)
Query: 271 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 330
+ + LQ E EKNK ++ I + +E KE +NN +L+ V D + L
Sbjct: 1791 QSMIGHLQEELEEKNKK----YSLIVAQHVE----KEGGKNNIQAKQNLENVFDDVQKTL 1842
Query: 331 KELDKEIRPFRQNWEEADSM--------KSSVESLQNRVTELESVDKSAGQVARNTGLLE 382
+E + + Q +E DS + +E L ++ +L+++ + G+ + T LLE
Sbjct: 1843 QEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGR-NKPTELLE 1901
Query: 383 SQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTL 438
+ V L++M+ + LE +K+ +R KQ+ +GK +
Sbjct: 1902 ENTEEKSKSHLVQPKLLSNMEAQHNDLE---------FKLAGAEREKQK--LGKEI 1946
Score = 29.6 bits (65), Expect = 7.8
Identities = 30/143 (20%), Positives = 55/143 (38%), Gaps = 3/143 (2%)
Query: 248 IKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKE 307
IK S + L E N+L ++ EK I+S+ I S E E ++
Sbjct: 1266 IKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQK 1325
Query: 308 MLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESV 367
N + + I + KEL + I EE K + SL ++T+L
Sbjct: 1326 EGGNQQQAASEKESCI---TQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQ 1382
Query: 368 DKSAGQVARNTGLLESQLSRHDQ 390
+++ ++ + S ++D+
Sbjct: 1383 LQNSISLSEKEAAISSLRKQYDE 1405
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 43.9 bits (102), Expect = 4e-04
Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 8/139 (5%)
Query: 259 HVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILH 318
H LL +E KV++LQ E E + L +Q +E E+ + L E K
Sbjct: 745 HCELLTVKIKKMEDKVNVLQRELSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEK--- 801
Query: 319 LQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVE-SLQNRVTELESVDKSAGQVARN 377
+R D+ EK++E ++R + + + +K +E SLQ EL +V + QV +
Sbjct: 802 -RRNADTLYEKIRE---QLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQVVQE 857
Query: 378 TGLLESQLSRHDQMLSVHD 396
+ QLSR + D
Sbjct: 858 RNDAQRQLSREQNARMLQD 876
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,055,001
Number of Sequences: 37866
Number of extensions: 1013878
Number of successful extensions: 6885
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 438
Number of HSP's that attempted gapping in prelim test: 5408
Number of HSP's gapped (non-prelim): 1545
length of query: 568
length of database: 18,247,518
effective HSP length: 108
effective length of query: 460
effective length of database: 14,157,990
effective search space: 6512675400
effective search space used: 6512675400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.